CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 Gene3D G3DSA:3.90.110.10 150 311 2.9E-47 T 29-03-2018 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 3.3E-29 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 3.3E-29 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 3.3E-29 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 3.3E-29 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 3.3E-29 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 307 4.7E-27 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 3.0E-152 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 1.6E-43 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 Gene3D G3DSA:3.40.50.720 7 149 6.3E-39 T 29-03-2018 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 SUPERFAMILY SSF56327 151 309 1.73E-52 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 SUPERFAMILY SSF51735 7 147 5.08E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 PIRSF PIRSF000102 2 311 1.0E-103 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CB4_RS18385 e67a4cf6cf40ed1738297a64e7ad0938 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 46.301 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 Pfam PF01266 FAD dependent oxidoreductase 23 348 6.3E-51 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 406 534 2.8E-24 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 27 44 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 374 384 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 Gene3D G3DSA:3.50.50.60 2 420 4.1E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 339 345 5.4E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 369 381 5.4E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 96 108 5.4E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 22 34 5.4E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 35 45 5.4E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 51 63 5.4E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 SUPERFAMILY SSF54373 252 345 4.58E-11 T 29-03-2018 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 SUPERFAMILY SSF51905 22 286 9.72E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS04685 6044aaeaf368710e62fb27f36a6a4358 557 SUPERFAMILY SSF51905 338 397 9.72E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05800 5f61815b665a7fe77f667b16b75254bc 202 Hamap MF_00528 Septum formation protein Maf [maf]. 9 201 31.716 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CB4_RS05800 5f61815b665a7fe77f667b16b75254bc 202 Gene3D G3DSA:3.90.950.10 1 197 2.1E-69 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CB4_RS05800 5f61815b665a7fe77f667b16b75254bc 202 PIRSF PIRSF006305 1 202 2.5E-52 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CB4_RS05800 5f61815b665a7fe77f667b16b75254bc 202 TIGRFAM TIGR00172 maf: septum formation protein Maf 9 192 2.9E-49 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CB4_RS05800 5f61815b665a7fe77f667b16b75254bc 202 Pfam PF02545 Maf-like protein 10 196 6.2E-57 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CB4_RS05800 5f61815b665a7fe77f667b16b75254bc 202 SUPERFAMILY SSF52972 8 196 7.19E-59 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CB4_RS06025 0d199226597ea8b4a2d63116c25a1979 498 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 90 489 1.3E-148 T 29-03-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ CB4_RS06025 0d199226597ea8b4a2d63116c25a1979 498 Gene3D G3DSA:3.20.20.70 120 496 2.0E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS06025 0d199226597ea8b4a2d63116c25a1979 498 SMART SM00729 173 397 6.3E-47 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS06025 0d199226597ea8b4a2d63116c25a1979 498 Pfam PF04055 Radical SAM superfamily 181 352 1.3E-19 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS06025 0d199226597ea8b4a2d63116c25a1979 498 SUPERFAMILY SSF102114 168 484 3.66E-70 T 29-03-2018 CB4_RS11275 60c13c37b9430be31674394879d304b4 464 Gene3D G3DSA:3.30.70.260 282 373 2.9E-16 T 29-03-2018 CB4_RS11275 60c13c37b9430be31674394879d304b4 464 Gene3D G3DSA:3.40.1160.10 1 281 4.3E-59 T 29-03-2018 CB4_RS11275 60c13c37b9430be31674394879d304b4 464 SUPERFAMILY SSF53633 1 287 4.06E-68 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS11275 60c13c37b9430be31674394879d304b4 464 Pfam PF00696 Amino acid kinase family 2 276 4.5E-42 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS11275 60c13c37b9430be31674394879d304b4 464 Gene3D G3DSA:3.30.70.260 374 454 1.6E-20 T 29-03-2018 CB4_RS11275 60c13c37b9430be31674394879d304b4 464 SUPERFAMILY SSF55021 296 358 2.21E-8 T 29-03-2018 CB4_RS11275 60c13c37b9430be31674394879d304b4 464 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 449 9.6E-82 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS11275 60c13c37b9430be31674394879d304b4 464 PIRSF PIRSF000726 1 455 8.2E-77 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS11275 60c13c37b9430be31674394879d304b4 464 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS11275 60c13c37b9430be31674394879d304b4 464 SUPERFAMILY SSF55021 371 450 1.9E-20 T 29-03-2018 CB4_RS07565 24d0daa9bdc6213c89a305da6bac8014 351 Pfam PF01699 Sodium/calcium exchanger protein 32 180 3.6E-17 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CB4_RS07565 24d0daa9bdc6213c89a305da6bac8014 351 Pfam PF01699 Sodium/calcium exchanger protein 206 344 2.2E-16 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CB4_RS07565 24d0daa9bdc6213c89a305da6bac8014 351 TIGRFAM TIGR00378 cax: calcium/proton exchanger 12 349 8.7E-109 T 29-03-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 CB4_RS16785 a32286248b4e195d1b6c1e6ae88a50b4 133 SUPERFAMILY SSF55874 19 121 6.82E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16785 a32286248b4e195d1b6c1e6ae88a50b4 133 Gene3D G3DSA:3.30.565.10 7 120 2.6E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16785 a32286248b4e195d1b6c1e6ae88a50b4 133 Pfam PF13581 Histidine kinase-like ATPase domain 40 127 4.2E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15125 c383e274df738a304f1cc5c0506c112b 505 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 27 488 2.6E-170 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS15125 c383e274df738a304f1cc5c0506c112b 505 SUPERFAMILY SSF56322 16 493 1.44E-154 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CB4_RS15125 c383e274df738a304f1cc5c0506c112b 505 Pfam PF00425 chorismate binding enzyme 228 481 6.8E-97 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CB4_RS15125 c383e274df738a304f1cc5c0506c112b 505 Pfam PF04715 Anthranilate synthase component I, N terminal region 28 165 3.0E-34 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS15125 c383e274df738a304f1cc5c0506c112b 505 PRINTS PR00095 Anthranilate synthase component I signature 343 356 1.2E-22 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS15125 c383e274df738a304f1cc5c0506c112b 505 PRINTS PR00095 Anthranilate synthase component I signature 438 452 1.2E-22 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS15125 c383e274df738a304f1cc5c0506c112b 505 PRINTS PR00095 Anthranilate synthase component I signature 329 342 1.2E-22 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS15125 c383e274df738a304f1cc5c0506c112b 505 PRINTS PR00095 Anthranilate synthase component I signature 423 437 1.2E-22 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS15125 c383e274df738a304f1cc5c0506c112b 505 Gene3D G3DSA:3.60.120.10 15 491 1.9E-161 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CB4_RS02385 d3a746904e43bbb119d11af524fe71ff 323 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 10 161 3.8E-64 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CB4_RS02385 d3a746904e43bbb119d11af524fe71ff 323 Pfam PF01641 SelR domain 187 305 2.2E-50 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CB4_RS02385 d3a746904e43bbb119d11af524fe71ff 323 Gene3D G3DSA:3.30.1060.10 1 175 1.4E-65 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CB4_RS02385 d3a746904e43bbb119d11af524fe71ff 323 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 180 306 38.459 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CB4_RS02385 d3a746904e43bbb119d11af524fe71ff 323 Gene3D G3DSA:2.170.150.20 176 322 3.2E-58 T 29-03-2018 CB4_RS02385 d3a746904e43bbb119d11af524fe71ff 323 SUPERFAMILY SSF55068 9 173 2.22E-71 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CB4_RS02385 d3a746904e43bbb119d11af524fe71ff 323 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 182 314 5.6E-66 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CB4_RS02385 d3a746904e43bbb119d11af524fe71ff 323 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 9 168 36.524 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CB4_RS02385 d3a746904e43bbb119d11af524fe71ff 323 Pfam PF01625 Peptide methionine sulfoxide reductase 12 162 2.1E-60 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CB4_RS02385 d3a746904e43bbb119d11af524fe71ff 323 SUPERFAMILY SSF51316 181 322 3.56E-62 T 29-03-2018 IPR011057 Mss4-like CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 Pfam PF00395 S-layer homology domain 820 861 6.2E-6 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 Pfam PF00395 S-layer homology domain 747 789 4.4E-15 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 Pfam PF00395 S-layer homology domain 689 730 6.3E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 Pfam PF02368 Bacterial Ig-like domain (group 2) 350 428 5.7E-15 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 SMART SM00635 350 428 4.0E-19 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 SUPERFAMILY SSF49373 348 431 1.14E-21 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 1 63 1.5E-18 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 69 133 3.0E-20 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 279 343 8.2E-19 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 139 202 5.3E-19 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 209 273 3.6E-21 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 Gene3D G3DSA:2.60.40.1080 345 434 7.1E-26 T 29-03-2018 CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 238 277 1.5E-9 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 28 67 3.4E-7 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 98 137 2.4E-7 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 308 345 5.6E-6 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS04640 dec4bd56717ed37f55fe88771593c028 874 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 168 207 8.4E-8 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS18680 c5cc2d95f8f983e2d9c5ca00f5656891 513 Pfam PF01266 FAD dependent oxidoreductase 39 382 1.1E-37 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CB4_RS18680 c5cc2d95f8f983e2d9c5ca00f5656891 513 Gene3D G3DSA:3.50.50.60 25 417 5.0E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS18680 c5cc2d95f8f983e2d9c5ca00f5656891 513 PRINTS PR00162 Rieske 2Fe-2S subunit signature 483 495 1.3E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CB4_RS18680 c5cc2d95f8f983e2d9c5ca00f5656891 513 PRINTS PR00162 Rieske 2Fe-2S subunit signature 462 473 1.3E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CB4_RS18680 c5cc2d95f8f983e2d9c5ca00f5656891 513 PRINTS PR00162 Rieske 2Fe-2S subunit signature 495 507 1.3E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CB4_RS18680 c5cc2d95f8f983e2d9c5ca00f5656891 513 Pfam PF00355 Rieske [2Fe-2S] domain 430 510 9.3E-15 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CB4_RS18680 c5cc2d95f8f983e2d9c5ca00f5656891 513 SUPERFAMILY SSF50022 421 511 2.36E-26 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CB4_RS18680 c5cc2d95f8f983e2d9c5ca00f5656891 513 SUPERFAMILY SSF51971 328 390 2.47E-31 T 29-03-2018 CB4_RS18680 c5cc2d95f8f983e2d9c5ca00f5656891 513 SUPERFAMILY SSF51971 36 267 2.47E-31 T 29-03-2018 CB4_RS18680 c5cc2d95f8f983e2d9c5ca00f5656891 513 Gene3D G3DSA:2.102.10.10 418 513 4.0E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 SUPERFAMILY SSF52540 273 413 1.49E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 SUPERFAMILY SSF52540 440 559 1.49E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 Pfam PF04851 Type III restriction enzyme, res subunit 226 373 1.9E-30 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 SMART SM00487 224 397 4.0E-11 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 Gene3D G3DSA:3.40.50.300 215 388 3.0E-23 T 29-03-2018 CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 SMART SM00490 467 548 5.0E-13 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 Pfam PF00271 Helicase conserved C-terminal domain 449 546 3.8E-13 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 Gene3D G3DSA:3.40.50.300 432 760 6.4E-24 T 29-03-2018 CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 Pfam PF13091 PLD-like domain 18 140 4.3E-11 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 SUPERFAMILY SSF56024 10 151 2.25E-9 T 29-03-2018 CB4_RS12785 d027b3f90b3f2cafb97502afaf8ee387 817 Gene3D G3DSA:3.30.870.10 2 197 6.1E-15 T 29-03-2018 CB4_RS10055 df8f20a932a3eeff92afe100f62b0e27 452 SUPERFAMILY SSF56059 205 412 3.89E-14 T 29-03-2018 CB4_RS10055 df8f20a932a3eeff92afe100f62b0e27 452 Pfam PF14398 YheC/D like ATP-grasp 183 439 4.6E-71 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CB4_RS10055 df8f20a932a3eeff92afe100f62b0e27 452 Gene3D G3DSA:3.30.470.20 284 419 2.9E-14 T 29-03-2018 CB4_RS10055 df8f20a932a3eeff92afe100f62b0e27 452 Gene3D G3DSA:3.30.1490.20 212 283 2.7E-10 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS09710 39d011384e6d6c5c533bc92ebecc458e 239 Gene3D G3DSA:3.30.70.980 171 239 4.0E-10 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS09710 39d011384e6d6c5c533bc92ebecc458e 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 6.9E-71 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS09710 39d011384e6d6c5c533bc92ebecc458e 239 SUPERFAMILY SSF75625 1 239 1.96E-80 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS09710 39d011384e6d6c5c533bc92ebecc458e 239 Pfam PF01709 Transcriptional regulator 4 235 1.8E-81 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS09710 39d011384e6d6c5c533bc92ebecc458e 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 55.463 T 29-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN CB4_RS09710 39d011384e6d6c5c533bc92ebecc458e 239 Gene3D G3DSA:1.10.10.200 2 76 4.5E-26 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CB4_RS09710 39d011384e6d6c5c533bc92ebecc458e 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.437 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS09710 39d011384e6d6c5c533bc92ebecc458e 239 Gene3D G3DSA:3.30.70.980 80 170 1.2E-26 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS06510 bcdddb2a651280ea1e9170117459fc50 284 SUPERFAMILY SSF58104 119 282 1.83E-42 T 29-03-2018 CB4_RS06510 bcdddb2a651280ea1e9170117459fc50 284 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 133 279 3.9E-28 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS06510 bcdddb2a651280ea1e9170117459fc50 284 Gene3D G3DSA:1.10.287.950 66 284 3.2E-37 T 29-03-2018 CB4_RS06510 bcdddb2a651280ea1e9170117459fc50 284 SMART SM00283 75 283 1.1E-7 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 SUPERFAMILY SSF58104 226 260 7.85E-72 T 29-03-2018 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 SUPERFAMILY SSF58104 293 562 7.85E-72 T 29-03-2018 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 SMART SM00304 204 258 1.4E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 514 1.8E-42 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 SMART SM00283 287 562 5.6E-62 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 Gene3D G3DSA:1.20.120.30 19 171 5.2E-4 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 Gene3D G3DSA:1.10.287.950 320 563 7.0E-52 T 29-03-2018 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 Gene3D G3DSA:1.20.1480.30 212 319 0.0027 T 29-03-2018 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 385 412 1.8E-20 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 414 443 1.8E-20 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 13 1.8E-20 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 Pfam PF00672 HAMP domain 204 254 6.0E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS06975 fa9bbd30254810240411f56fe5309859 563 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 170 1.2E-11 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 SMART SM00387 633 742 6.4E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 Gene3D G3DSA:1.10.287.130 511 581 2.0E-17 T 29-03-2018 CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 635 728 1.1E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 SMART SM00388 521 587 4.6E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 PRINTS PR00344 Bacterial sensor protein C-terminal signature 688 698 4.0E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 PRINTS PR00344 Bacterial sensor protein C-terminal signature 703 721 4.0E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 Gene3D G3DSA:3.40.50.300 21 389 0.014 T 29-03-2018 CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 SUPERFAMILY SSF55874 576 726 9.47E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 Gene3D G3DSA:3.30.565.10 582 742 3.7E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 Pfam PF00512 His Kinase A (phospho-acceptor) domain 522 587 2.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS02230 e958b95f602330324e8487b7efb3d072 743 SUPERFAMILY SSF47384 510 588 1.9E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS05485 48fe823ba3e38afc9308fe365c5d50d1 254 Pfam PF01012 Electron transfer flavoprotein domain 23 205 2.0E-55 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CB4_RS05485 48fe823ba3e38afc9308fe365c5d50d1 254 SMART SM00893 21 209 1.1E-64 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CB4_RS05485 48fe823ba3e38afc9308fe365c5d50d1 254 PIRSF PIRSF000090 1 254 8.5E-83 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CB4_RS05485 48fe823ba3e38afc9308fe365c5d50d1 254 Gene3D G3DSA:3.40.50.620 1 254 2.5E-79 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS05485 48fe823ba3e38afc9308fe365c5d50d1 254 SUPERFAMILY SSF52402 1 248 1.33E-81 T 29-03-2018 CB4_RS05485 48fe823ba3e38afc9308fe365c5d50d1 254 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 153 173 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 230 2.8E-64 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 PRINTS PR00783 Major intrinsic protein family signature 2 21 1.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 PRINTS PR00783 Major intrinsic protein family signature 136 154 1.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 PRINTS PR00783 Major intrinsic protein family signature 166 188 1.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 PRINTS PR00783 Major intrinsic protein family signature 44 68 1.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 PRINTS PR00783 Major intrinsic protein family signature 81 100 1.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 PRINTS PR00783 Major intrinsic protein family signature 213 233 1.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 ProSitePatterns PS00221 MIP family signature. 62 70 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 Gene3D G3DSA:1.20.1080.10 1 240 1.3E-84 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 Pfam PF00230 Major intrinsic protein 3 230 5.2E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CB4_RS04675 61be26d5c27232cc377abdb46ae6d608 269 SUPERFAMILY SSF81338 2 235 2.49E-71 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 Pfam PF04998 RNA polymerase Rpb1, domain 5 772 1130 7.7E-68 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 665 3.0E-31 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 Gene3D G3DSA:2.40.50.100 912 1030 2.9E-40 T 29-03-2018 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 474 1.1E-37 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 1.7E-88 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 SUPERFAMILY SSF64484 5 1183 0.0 T 29-03-2018 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 Gene3D G3DSA:2.40.40.20 335 477 7.5E-40 T 29-03-2018 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1182 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 SMART SM00663 224 503 3.1E-183 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1196 18.574 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01125 cc146d5d38bcb4e08ced912eb128a2a7 1213 Pfam PF05000 RNA polymerase Rpb1, domain 4 694 762 1.4E-13 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS04355 e8e47aa270911e79288f6287492291cd 125 Gene3D G3DSA:2.60.40.420 20 125 1.6E-12 T 29-03-2018 IPR008972 Cupredoxin CB4_RS04355 e8e47aa270911e79288f6287492291cd 125 SUPERFAMILY SSF49503 30 124 1.79E-16 T 29-03-2018 IPR008972 Cupredoxin CB4_RS04355 e8e47aa270911e79288f6287492291cd 125 Pfam PF13473 Cupredoxin-like domain 14 112 3.8E-14 T 29-03-2018 IPR028096 EfeO-type cupredoxin-like domain CB4_RS09845 88bd8262d824ea4ac4c51b4659b98e96 381 Gene3D G3DSA:1.20.140.10 221 380 1.4E-49 T 29-03-2018 CB4_RS09845 88bd8262d824ea4ac4c51b4659b98e96 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 1.8E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS09845 88bd8262d824ea4ac4c51b4659b98e96 381 SUPERFAMILY SSF56645 5 243 2.62E-90 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CB4_RS09845 88bd8262d824ea4ac4c51b4659b98e96 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS09845 88bd8262d824ea4ac4c51b4659b98e96 381 SUPERFAMILY SSF47203 229 379 3.87E-47 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS09845 88bd8262d824ea4ac4c51b4659b98e96 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS09845 88bd8262d824ea4ac4c51b4659b98e96 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 1.6E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS09845 88bd8262d824ea4ac4c51b4659b98e96 381 Gene3D G3DSA:2.40.110.10 121 220 4.1E-40 T 29-03-2018 CB4_RS09845 88bd8262d824ea4ac4c51b4659b98e96 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 1.3E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CB4_RS09845 88bd8262d824ea4ac4c51b4659b98e96 381 Gene3D G3DSA:1.10.540.10 2 120 2.3E-35 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS18920 a18adf0ba5561093f4ccbed50964c25c 264 Pfam PF12671 Putative amidase domain 104 261 3.2E-36 T 29-03-2018 IPR024301 Putative amidase domain CB4_RS18920 a18adf0ba5561093f4ccbed50964c25c 264 Gene3D G3DSA:3.90.1720.10 94 263 1.1E-13 T 29-03-2018 CB4_RS12305 d1904c4eda9386fcadf7b4836a509848 262 Gene3D G3DSA:3.30.420.10 30 217 2.1E-28 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS12305 d1904c4eda9386fcadf7b4836a509848 262 SMART SM00479 31 211 2.2E-26 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS12305 d1904c4eda9386fcadf7b4836a509848 262 SUPERFAMILY SSF53098 29 229 2.32E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS12305 d1904c4eda9386fcadf7b4836a509848 262 Pfam PF00929 Exonuclease 33 202 2.2E-17 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS03320 47a241719eb939cefe8ffab6eb0e999e 157 Gene3D G3DSA:3.90.20.10 91 157 6.7E-4 T 29-03-2018 CB4_RS03320 47a241719eb939cefe8ffab6eb0e999e 157 Gene3D G3DSA:1.20.5.320 12 50 6.4E-11 T 29-03-2018 CB4_RS03320 47a241719eb939cefe8ffab6eb0e999e 157 Gene3D G3DSA:1.20.5.170 51 90 0.0011 T 29-03-2018 CB4_RS03320 47a241719eb939cefe8ffab6eb0e999e 157 SUPERFAMILY SSF58100 9 143 5.23E-7 T 29-03-2018 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Gene3D G3DSA:2.30.30.40 788 832 5.0E-19 T 29-03-2018 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SUPERFAMILY SSF50341 549 682 2.35E-33 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Gene3D G3DSA:2.30.30.40 551 586 0.0022 T 29-03-2018 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Gene3D G3DSA:2.30.30.40 629 667 4.3E-18 T 29-03-2018 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SMART SM00387 407 550 2.6E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SUPERFAMILY SSF55052 171 253 1.15E-19 T 29-03-2018 IPR015162 CheY binding CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 466 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 547 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 528 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Pfam PF01584 CheW-like domain 706 839 2.5E-35 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Pfam PF01584 CheW-like domain 556 684 2.3E-25 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Gene3D G3DSA:1.20.120.160 2 149 2.8E-29 T 29-03-2018 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SUPERFAMILY SSF47226 6 129 6.15E-31 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SMART SM00073 6 103 3.4E-31 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Pfam PF01627 Hpt domain 10 97 3.9E-17 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SUPERFAMILY SSF55874 364 548 2.88E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 411 549 1.3E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Gene3D G3DSA:3.30.565.10 364 550 8.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SUPERFAMILY SSF47384 296 363 3.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Gene3D G3DSA:1.10.287.560 294 363 8.1E-18 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Gene3D G3DSA:2.40.50.180 668 727 0.058 T 29-03-2018 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Gene3D G3DSA:3.30.70.1110 173 253 2.0E-22 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SMART SM01231 294 362 3.0E-17 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 296 362 3.3E-17 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SMART SM00260 542 682 1.0E-34 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SMART SM00260 702 838 1.1E-34 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Gene3D G3DSA:2.40.50.180 728 787 3.0E-19 T 29-03-2018 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Gene3D G3DSA:2.40.50.180 587 628 5.4E-11 T 29-03-2018 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 Pfam PF07194 P2 response regulator binding domain 176 254 5.4E-21 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CB4_RS20730 12d1c1578f6639cd1badeea14e81b08b 853 SUPERFAMILY SSF50341 700 841 7.98E-36 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS07990 f76dd50534cef1a8aa048a22e7754e8b 272 PIRSF PIRSF005578 1 267 1.1E-101 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CB4_RS07990 f76dd50534cef1a8aa048a22e7754e8b 272 SUPERFAMILY SSF55174 5 70 9.57E-13 T 29-03-2018 CB4_RS07990 f76dd50534cef1a8aa048a22e7754e8b 272 Gene3D G3DSA:3.40.50.150 64 272 1.4E-59 T 29-03-2018 CB4_RS07990 f76dd50534cef1a8aa048a22e7754e8b 272 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 238 1.3E-81 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CB4_RS07990 f76dd50534cef1a8aa048a22e7754e8b 272 SUPERFAMILY SSF53335 56 245 6.81E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS07990 f76dd50534cef1a8aa048a22e7754e8b 272 Pfam PF01728 FtsJ-like methyltransferase 61 241 8.5E-17 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CB4_RS07990 f76dd50534cef1a8aa048a22e7754e8b 272 SMART SM00363 5 70 4.7E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS07990 f76dd50534cef1a8aa048a22e7754e8b 272 Pfam PF01479 S4 domain 5 49 1.4E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS07990 f76dd50534cef1a8aa048a22e7754e8b 272 Gene3D G3DSA:3.10.290.10 1 63 4.4E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS02170 b5a4a2e05a281bfd884a5f4bc6daab2a 308 SUPERFAMILY SSF103481 52 143 2.48E-10 T 29-03-2018 CB4_RS02170 b5a4a2e05a281bfd884a5f4bc6daab2a 308 Pfam PF00892 EamA-like transporter family 9 142 1.3E-23 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS02170 b5a4a2e05a281bfd884a5f4bc6daab2a 308 Pfam PF00892 EamA-like transporter family 155 297 4.2E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS02170 b5a4a2e05a281bfd884a5f4bc6daab2a 308 SUPERFAMILY SSF103481 214 300 1.7E-13 T 29-03-2018 CB4_RS17095 be7e8239965381d3268e1e7c203716d1 396 PIRSF PIRSF005962 7 395 1.2E-131 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CB4_RS17095 be7e8239965381d3268e1e7c203716d1 396 SUPERFAMILY SSF53187 12 205 1.2E-81 T 29-03-2018 CB4_RS17095 be7e8239965381d3268e1e7c203716d1 396 SUPERFAMILY SSF53187 306 390 1.2E-81 T 29-03-2018 CB4_RS17095 be7e8239965381d3268e1e7c203716d1 396 Pfam PF01546 Peptidase family M20/M25/M40 80 386 5.6E-36 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CB4_RS17095 be7e8239965381d3268e1e7c203716d1 396 SUPERFAMILY SSF55031 190 299 1.96E-33 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CB4_RS17095 be7e8239965381d3268e1e7c203716d1 396 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 23 381 8.4E-122 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CB4_RS17095 be7e8239965381d3268e1e7c203716d1 396 Pfam PF07687 Peptidase dimerisation domain 190 284 5.8E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CB4_RS17095 be7e8239965381d3268e1e7c203716d1 396 Gene3D G3DSA:3.40.630.10 254 396 1.9E-27 T 29-03-2018 CB4_RS17095 be7e8239965381d3268e1e7c203716d1 396 Gene3D G3DSA:3.40.630.10 1 253 1.7E-49 T 29-03-2018 CB4_RS20360 f8460a176e46640d07489361383218a3 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 334 1.6E-144 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CB4_RS20360 f8460a176e46640d07489361383218a3 346 SUPERFAMILY SSF56042 168 337 8.67E-59 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20360 f8460a176e46640d07489361383218a3 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 53 161 5.9E-18 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20360 f8460a176e46640d07489361383218a3 346 Gene3D G3DSA:3.90.650.10 168 341 1.1E-62 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20360 f8460a176e46640d07489361383218a3 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 344 47.811 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CB4_RS20360 f8460a176e46640d07489361383218a3 346 Gene3D G3DSA:3.30.1330.10 32 158 4.6E-57 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20360 f8460a176e46640d07489361383218a3 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 337 1.8E-33 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20360 f8460a176e46640d07489361383218a3 346 SUPERFAMILY SSF55326 4 167 2.99E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS09775 b96fce5d90a5619e9ae70f9c4bda5787 262 Pfam PF02867 Ribonucleotide reductase, barrel domain 228 262 3.5E-6 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09775 b96fce5d90a5619e9ae70f9c4bda5787 262 Gene3D G3DSA:3.20.70.20 127 262 6.7E-38 T 29-03-2018 CB4_RS09775 b96fce5d90a5619e9ae70f9c4bda5787 262 SUPERFAMILY SSF48168 8 223 1.27E-53 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09775 b96fce5d90a5619e9ae70f9c4bda5787 262 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 147 224 6.1E-19 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09775 b96fce5d90a5619e9ae70f9c4bda5787 262 SUPERFAMILY SSF51998 227 262 2.98E-8 T 29-03-2018 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 Gene3D G3DSA:3.50.50.60 203 323 5.2E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.1E-17 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 284 302 1.1E-17 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 1.1E-17 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 131 1.1E-17 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 293 9.0E-90 T 29-03-2018 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 Gene3D G3DSA:3.50.50.60 3 149 1.7E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 4 322 8.5E-135 T 29-03-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 261 2.2E-13 T 29-03-2018 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 2.2E-13 T 29-03-2018 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 2.2E-13 T 29-03-2018 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.2E-13 T 29-03-2018 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 SUPERFAMILY SSF51905 3 322 1.64E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15295 964077e9c4b12e9284170a688b67a990 323 Gene3D G3DSA:3.50.50.60 150 202 1.4E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 SUPERFAMILY SSF51905 2 201 1.05E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Pfam PF01206 Sulfurtransferase TusA 588 655 1.6E-17 T 29-03-2018 IPR001455 TusA-like domain CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 SUPERFAMILY SSF55424 326 450 2.41E-34 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Pfam PF13686 DsrE/DsrF/DrsH-like family 671 825 2.5E-61 T 29-03-2018 IPR032836 DsrE2-like family CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 SUPERFAMILY SSF75169 768 814 8.64E-19 T 29-03-2018 IPR027396 DsrEFH-like CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 SUPERFAMILY SSF75169 673 718 8.64E-19 T 29-03-2018 IPR027396 DsrEFH-like CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 SUPERFAMILY SSF64307 573 655 4.97E-20 T 29-03-2018 IPR001455 TusA-like domain CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 333 434 3.7E-16 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Gene3D G3DSA:3.30.110.40 563 656 1.5E-23 T 29-03-2018 IPR001455 TusA-like domain CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Pfam PF00581 Rhodanese-like domain 466 546 9.7E-12 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 309 2.4E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 SUPERFAMILY SSF52821 437 550 2.1E-29 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 SUPERFAMILY SSF51905 156 320 1.79E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 5.1E-21 T 29-03-2018 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 5.1E-21 T 29-03-2018 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.1E-21 T 29-03-2018 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 5.1E-21 T 29-03-2018 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 254 5.1E-21 T 29-03-2018 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Gene3D G3DSA:3.40.250.10 457 558 3.4E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Gene3D G3DSA:3.30.390.30 330 456 7.4E-30 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.3E-15 T 29-03-2018 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 280 287 1.3E-15 T 29-03-2018 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 1.3E-15 T 29-03-2018 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 239 253 1.3E-15 T 29-03-2018 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 588 612 - T 29-03-2018 IPR001455 TusA-like domain CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Gene3D G3DSA:3.50.50.60 1 144 1.7E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 SMART SM00450 454 550 2.8E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Gene3D G3DSA:3.40.1260.10 668 826 3.3E-55 T 29-03-2018 CB4_RS13025 bd3579a8f65d1383212aaf72936af6c5 826 Gene3D G3DSA:3.50.50.60 149 329 3.9E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS12680 b092faa0122cd41e0dc1563e7db343b0 603 SUPERFAMILY SSF49503 316 454 7.55E-30 T 29-03-2018 IPR008972 Cupredoxin CB4_RS12680 b092faa0122cd41e0dc1563e7db343b0 603 SUPERFAMILY SSF49503 473 577 8.3E-34 T 29-03-2018 IPR008972 Cupredoxin CB4_RS12680 b092faa0122cd41e0dc1563e7db343b0 603 Pfam PF02535 ZIP Zinc transporter 106 225 1.9E-9 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CB4_RS12680 b092faa0122cd41e0dc1563e7db343b0 603 Pfam PF07732 Multicopper oxidase 337 455 6.9E-24 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CB4_RS12680 b092faa0122cd41e0dc1563e7db343b0 603 Gene3D G3DSA:2.60.40.420 296 451 6.5E-32 T 29-03-2018 IPR008972 Cupredoxin CB4_RS12680 b092faa0122cd41e0dc1563e7db343b0 603 Pfam PF07731 Multicopper oxidase 481 576 1.5E-24 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CB4_RS12680 b092faa0122cd41e0dc1563e7db343b0 603 Gene3D G3DSA:2.60.40.420 452 580 4.2E-36 T 29-03-2018 IPR008972 Cupredoxin CB4_RS08300 d9a1959a301dfda6a426b963b9ad18c1 200 PIRSF PIRSF020606 1 199 7.0E-76 T 29-03-2018 IPR014509 Uncharacterised conserved protein UCP020606 CB4_RS08300 d9a1959a301dfda6a426b963b9ad18c1 200 Pfam PF09997 Predicted membrane protein (DUF2238) 37 177 7.0E-56 T 29-03-2018 IPR014509 Uncharacterised conserved protein UCP020606 CB4_RS12205 fba9763bfb532b0ea07c23cd97c0064d 364 Gene3D G3DSA:3.90.1200.10 43 344 2.1E-14 T 29-03-2018 CB4_RS12205 fba9763bfb532b0ea07c23cd97c0064d 364 SUPERFAMILY SSF56112 56 335 4.34E-23 T 29-03-2018 IPR011009 Protein kinase-like domain CB4_RS12205 fba9763bfb532b0ea07c23cd97c0064d 364 Pfam PF01636 Phosphotransferase enzyme family 66 274 5.1E-11 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CB4_RS18460 eae80bbdd497f01809cf7653e893accc 367 Pfam PF13378 Enolase C-terminal domain-like 143 355 6.7E-52 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CB4_RS18460 eae80bbdd497f01809cf7653e893accc 367 Gene3D G3DSA:3.20.20.120 129 357 2.4E-63 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CB4_RS18460 eae80bbdd497f01809cf7653e893accc 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 6 124 5.0E-21 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CB4_RS18460 eae80bbdd497f01809cf7653e893accc 367 SMART SM00922 141 240 4.5E-26 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CB4_RS18460 eae80bbdd497f01809cf7653e893accc 367 Gene3D G3DSA:3.30.390.10 1 128 3.2E-31 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS18460 eae80bbdd497f01809cf7653e893accc 367 SUPERFAMILY SSF54826 1 125 1.98E-32 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS18460 eae80bbdd497f01809cf7653e893accc 367 SUPERFAMILY SSF51604 112 355 9.96E-66 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CB4_RS03130 f9cba53fa6bd6ef10c4fd08c23480974 184 PIRSF PIRSF019083 18 183 2.6E-41 T 29-03-2018 IPR016747 Phosphotransbutyrylase CB4_RS03130 f9cba53fa6bd6ef10c4fd08c23480974 184 Pfam PF04892 VanZ like family 30 171 9.8E-16 T 29-03-2018 IPR006976 VanZ-like CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 1.2E-51 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 Gene3D G3DSA:1.10.540.10 1 120 1.9E-44 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 SUPERFAMILY SSF56645 1 242 6.28E-94 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 5.6E-43 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 Gene3D G3DSA:1.20.140.10 218 380 2.4E-67 T 29-03-2018 CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 1.4E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 PIRSF PIRSF016578 4 370 1.1E-20 T 29-03-2018 CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 Gene3D G3DSA:2.40.110.10 121 217 2.2E-39 T 29-03-2018 CB4_RS02770 2dcee5524fc38017ca67b25db2f32454 380 SUPERFAMILY SSF47203 227 379 7.09E-61 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 SUPERFAMILY SSF55785 9 109 2.79E-15 T 29-03-2018 IPR000014 PAS domain CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 SMART SM00382 162 306 1.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 Pfam PF02954 Bacterial regulatory protein, Fis family 421 461 1.2E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 SMART SM00091 10 75 2.0E-7 T 29-03-2018 IPR000014 PAS domain CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 Pfam PF00989 PAS fold 11 113 4.5E-13 T 29-03-2018 IPR013767 PAS fold GO:0006355 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 Pfam PF00158 Sigma-54 interaction domain 142 309 3.2E-71 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 SUPERFAMILY SSF46689 356 463 2.28E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 427 444 9.6E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 444 463 9.6E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 Gene3D G3DSA:1.10.10.60 421 463 1.6E-14 T 29-03-2018 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 SUPERFAMILY SSF52540 141 378 4.82E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 Gene3D G3DSA:3.40.50.300 137 315 4.2E-28 T 29-03-2018 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 Gene3D G3DSA:1.10.8.60 316 420 3.3E-19 T 29-03-2018 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 Gene3D G3DSA:3.30.450.20 2 134 1.9E-18 T 29-03-2018 CB4_RS16395 d64a3222f0b69ced05826a73d309f604 463 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 123 7.7E-17 T 29-03-2018 IPR000014 PAS domain CB4_RS18020 7be3522092e7243363ebb7f6bea1f917 217 SUPERFAMILY SSF51182 17 185 6.58E-28 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS18020 7be3522092e7243363ebb7f6bea1f917 217 SMART SM00835 17 159 4.6E-20 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CB4_RS18020 7be3522092e7243363ebb7f6bea1f917 217 Gene3D G3DSA:2.60.120.10 7 171 2.2E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS18020 7be3522092e7243363ebb7f6bea1f917 217 Pfam PF00190 Cupin 33 158 7.2E-11 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CB4_RS04935 afa71d93982f8954fd6b6315aa3e0167 846 Gene3D G3DSA:2.60.40.10 385 485 4.9E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS04935 afa71d93982f8954fd6b6315aa3e0167 846 Gene3D G3DSA:2.60.40.1260 694 798 1.0E-5 T 29-03-2018 IPR001322 Lamin Tail Domain CB4_RS04935 afa71d93982f8954fd6b6315aa3e0167 846 Pfam PF00395 S-layer homology domain 185 228 2.8E-10 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS04935 afa71d93982f8954fd6b6315aa3e0167 846 Pfam PF00395 S-layer homology domain 123 166 4.2E-10 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS04935 afa71d93982f8954fd6b6315aa3e0167 846 Pfam PF00395 S-layer homology domain 62 104 5.5E-12 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS04935 afa71d93982f8954fd6b6315aa3e0167 846 Gene3D G3DSA:2.60.40.10 595 683 7.4E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS04935 afa71d93982f8954fd6b6315aa3e0167 846 SUPERFAMILY SSF48726 595 675 9.34E-7 T 29-03-2018 IPR007110 Immunoglobulin-like domain CB4_RS04935 afa71d93982f8954fd6b6315aa3e0167 846 Gene3D G3DSA:2.60.40.10 488 579 9.9E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS04935 afa71d93982f8954fd6b6315aa3e0167 846 SUPERFAMILY SSF48726 491 571 3.14E-7 T 29-03-2018 IPR007110 Immunoglobulin-like domain CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 SUPERFAMILY SSF118116 488 678 6.28E-56 T 29-03-2018 CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 SMART SM00853 492 636 6.8E-51 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 126 9.5E-10 T 29-03-2018 CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 8.7E-37 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 Gene3D G3DSA:3.30.565.10 4 199 3.9E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 Gene3D G3DSA:3.30.230.10 214 326 4.1E-28 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 SMART SM01340 209 327 3.0E-53 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 SUPERFAMILY SSF54211 190 327 4.55E-35 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 676 27.432 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 Pfam PF08676 MutL C terminal dimerisation domain 493 636 5.4E-45 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 307 5.2E-96 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CB4_RS14665 6b6881e5fb63e31ebd6f65941c436105 680 SUPERFAMILY SSF55874 2 214 2.36E-56 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02085 3b3a39dd77bd8cf25240e0ea99c6e08c 218 Gene3D G3DSA:1.10.10.60 15 78 5.0E-11 T 29-03-2018 CB4_RS02085 3b3a39dd77bd8cf25240e0ea99c6e08c 218 SUPERFAMILY SSF48498 103 209 2.88E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS02085 3b3a39dd77bd8cf25240e0ea99c6e08c 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 78 5.4E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS02085 3b3a39dd77bd8cf25240e0ea99c6e08c 218 Pfam PF13305 WHG domain 106 192 3.6E-12 T 29-03-2018 IPR025996 WHG domain CB4_RS02085 3b3a39dd77bd8cf25240e0ea99c6e08c 218 SUPERFAMILY SSF46689 27 92 2.57E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS02085 3b3a39dd77bd8cf25240e0ea99c6e08c 218 Gene3D G3DSA:1.10.357.10 79 214 3.7E-20 T 29-03-2018 CB4_RS20440 9e7e61b1b20587ab67197f9279d5dad6 94 SMART SM00883 1 93 2.7E-54 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CB4_RS20440 9e7e61b1b20587ab67197f9279d5dad6 94 PRINTS PR00297 10kDa chaperonin signature 80 93 7.2E-31 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CB4_RS20440 9e7e61b1b20587ab67197f9279d5dad6 94 PRINTS PR00297 10kDa chaperonin signature 59 71 7.2E-31 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CB4_RS20440 9e7e61b1b20587ab67197f9279d5dad6 94 PRINTS PR00297 10kDa chaperonin signature 2 17 7.2E-31 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CB4_RS20440 9e7e61b1b20587ab67197f9279d5dad6 94 PRINTS PR00297 10kDa chaperonin signature 24 45 7.2E-31 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CB4_RS20440 9e7e61b1b20587ab67197f9279d5dad6 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 2.4E-36 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CB4_RS20440 9e7e61b1b20587ab67197f9279d5dad6 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 26.027 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CB4_RS20440 9e7e61b1b20587ab67197f9279d5dad6 94 Gene3D G3DSA:2.30.33.40 1 94 2.1E-39 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CB4_RS20440 9e7e61b1b20587ab67197f9279d5dad6 94 SUPERFAMILY SSF50129 2 93 4.1E-34 T 29-03-2018 IPR011032 GroES-like CB4_RS20440 9e7e61b1b20587ab67197f9279d5dad6 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CB4_RS06420 9f474bb77747ba1c2651e1eeb78961ca 314 Hamap MF_00323 Ferrochelatase [hemH]. 4 307 31.393 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CB4_RS06420 9f474bb77747ba1c2651e1eeb78961ca 314 TIGRFAM TIGR00109 hemH: ferrochelatase 2 306 4.0E-88 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CB4_RS06420 9f474bb77747ba1c2651e1eeb78961ca 314 ProSitePatterns PS00534 Ferrochelatase signature. 178 196 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CB4_RS06420 9f474bb77747ba1c2651e1eeb78961ca 314 SUPERFAMILY SSF53800 3 307 1.18E-88 T 29-03-2018 CB4_RS06420 9f474bb77747ba1c2651e1eeb78961ca 314 Pfam PF00762 Ferrochelatase 6 305 5.3E-83 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CB4_RS06420 9f474bb77747ba1c2651e1eeb78961ca 314 Gene3D G3DSA:3.40.50.1400 2 162 2.8E-26 T 29-03-2018 CB4_RS06420 9f474bb77747ba1c2651e1eeb78961ca 314 Gene3D G3DSA:3.40.50.1400 163 288 1.5E-44 T 29-03-2018 CB4_RS09910 f70991002d5e5aab34cb3a9918945e31 483 Gene3D G3DSA:3.40.309.10 266 460 9.5E-71 T 29-03-2018 CB4_RS09910 f70991002d5e5aab34cb3a9918945e31 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CB4_RS09910 f70991002d5e5aab34cb3a9918945e31 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CB4_RS09910 f70991002d5e5aab34cb3a9918945e31 483 Gene3D G3DSA:3.40.605.10 4 265 5.3E-87 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS09910 f70991002d5e5aab34cb3a9918945e31 483 Pfam PF00171 Aldehyde dehydrogenase family 21 471 3.1E-161 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS09910 f70991002d5e5aab34cb3a9918945e31 483 SUPERFAMILY SSF53720 8 475 1.7E-152 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 87 100 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 SUPERFAMILY SSF56655 8 264 1.19E-76 T 29-03-2018 CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 Gene3D G3DSA:3.30.540.10 1 152 5.8E-45 T 29-03-2018 CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 65 81 1.4E-40 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 87 103 1.4E-40 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 136 159 1.4E-40 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 43 63 1.4E-40 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 214 238 1.4E-40 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 183 204 1.4E-40 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 Pfam PF00459 Inositol monophosphatase family 8 253 1.0E-59 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CB4_RS17790 cb5261881316d833fe29e87a01344f9a 269 Gene3D G3DSA:3.40.190.80 153 268 3.2E-28 T 29-03-2018 CB4_RS04220 bceb9b3fcedee47c6a4f196a9012e144 403 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 227 389 1.0E-44 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS04220 bceb9b3fcedee47c6a4f196a9012e144 403 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 6 391 8.7E-103 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 Gene3D G3DSA:3.30.450.20 129 233 2.4E-10 T 29-03-2018 CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 Pfam PF00158 Sigma-54 interaction domain 398 563 1.3E-68 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 SMART SM00382 415 559 1.4E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 Gene3D G3DSA:3.10.580.10 7 128 1.4E-5 T 29-03-2018 CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 Gene3D G3DSA:1.10.10.60 665 702 1.3E-8 T 29-03-2018 CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 608 617 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 SUPERFAMILY SSF46689 608 701 1.03E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 Pfam PF13426 PAS domain 314 360 0.039 T 29-03-2018 IPR000014 PAS domain CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 SUPERFAMILY SSF52540 395 638 4.44E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 SUPERFAMILY SSF55785 131 227 8.19E-8 T 29-03-2018 IPR000014 PAS domain CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 SUPERFAMILY SSF54631 9 124 9.1E-7 T 29-03-2018 CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 SMART SM00091 131 197 0.0057 T 29-03-2018 IPR000014 PAS domain CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 Pfam PF13188 PAS domain 132 167 2.2E-5 T 29-03-2018 IPR000014 PAS domain CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 419 432 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 Gene3D G3DSA:1.10.8.60 568 664 6.0E-25 T 29-03-2018 CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 Gene3D G3DSA:3.30.450.20 244 396 8.8E-10 T 29-03-2018 CB4_RS00215 3a118b95b6c110d46c251e268f09f122 711 Gene3D G3DSA:3.40.50.300 397 567 9.4E-26 T 29-03-2018 CB4_RS05015 0721798e7214297ca9087a56727a5772 405 PIRSF PIRSF031134 1 400 2.7E-166 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CB4_RS05015 0721798e7214297ca9087a56727a5772 405 Gene3D G3DSA:3.30.200.20 1 111 7.2E-39 T 29-03-2018 CB4_RS05015 0721798e7214297ca9087a56727a5772 405 Gene3D G3DSA:3.90.1200.10 112 369 1.3E-15 T 29-03-2018 CB4_RS05015 0721798e7214297ca9087a56727a5772 405 SUPERFAMILY SSF56112 2 396 3.21E-96 T 29-03-2018 IPR011009 Protein kinase-like domain CB4_RS05015 0721798e7214297ca9087a56727a5772 405 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 405 199.265 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CB4_RS05015 0721798e7214297ca9087a56727a5772 405 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 32 396 9.9E-149 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CB4_RS05015 0721798e7214297ca9087a56727a5772 405 Pfam PF01636 Phosphotransferase enzyme family 32 272 1.2E-13 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CB4_RS10165 24afe2b178db0d7e07af6575c6527572 114 SUPERFAMILY SSF103481 5 102 3.27E-19 T 29-03-2018 CB4_RS10165 24afe2b178db0d7e07af6575c6527572 114 Pfam PF00893 Small Multidrug Resistance protein 1 92 1.1E-29 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 PRINTS PR00116 Arginase signature 122 149 1.1E-42 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 PRINTS PR00116 Arginase signature 99 114 1.1E-42 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 PRINTS PR00116 Arginase signature 260 274 1.1E-42 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 PRINTS PR00116 Arginase signature 225 254 1.1E-42 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 PRINTS PR00116 Arginase signature 176 194 1.1E-42 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 Pfam PF00491 Arginase family 8 297 1.4E-76 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 SUPERFAMILY SSF52768 8 300 4.32E-90 T 29-03-2018 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 TIGRFAM TIGR01229 rocF_arginase: arginase 10 303 5.5E-97 T 29-03-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 ProSitePatterns PS01053 Arginase family signature. 228 249 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 PIRSF PIRSF036979 3 299 4.4E-35 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00635 a300bc79f0af7c865482512d5282efed 303 Gene3D G3DSA:3.40.800.10 4 299 3.9E-90 T 29-03-2018 CB4_RS17620 59a66c96b59bebc6f86a35b068477b66 167 SUPERFAMILY SSF55040 13 155 7.06E-57 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CB4_RS17620 59a66c96b59bebc6f86a35b068477b66 167 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 3 158 35.647 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CB4_RS17620 59a66c96b59bebc6f86a35b068477b66 167 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 5 152 4.3E-64 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CB4_RS17620 59a66c96b59bebc6f86a35b068477b66 167 Pfam PF01967 MoaC family 16 150 1.8E-53 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CB4_RS17620 59a66c96b59bebc6f86a35b068477b66 167 Gene3D G3DSA:3.30.70.640 3 158 5.6E-66 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1210 1342 3.5E-31 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 707 967 4.2E-42 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 Pfam PF00702 haloacid dehalogenase-like hydrolase 943 1266 2.6E-21 T 29-03-2018 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 Gene3D G3DSA:3.40.1110.10 1001 1150 1.3E-32 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 Gene3D G3DSA:1.20.1110.10 1279 1499 3.2E-48 T 29-03-2018 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1110 1128 2.9E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1224 1240 2.9E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1252 1268 2.9E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1284 1309 2.9E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 Pfam PF00690 Cation transporter/ATPase, N-terminus 627 695 2.9E-11 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1150 1161 3.2E-36 T 29-03-2018 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 785 799 3.2E-36 T 29-03-2018 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 946 960 3.2E-36 T 29-03-2018 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1276 1288 3.2E-36 T 29-03-2018 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1252 1271 3.2E-36 T 29-03-2018 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1172 1182 3.2E-36 T 29-03-2018 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 SUPERFAMILY SSF56784 1107 1357 2.46E-55 T 29-03-2018 IPR023214 HAD-like domain CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 SUPERFAMILY SSF56784 944 964 2.46E-55 T 29-03-2018 IPR023214 HAD-like domain CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 948 954 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 SUPERFAMILY SSF81660 343 451 2.84E-5 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 Gene3D G3DSA:3.40.50.1000 1151 1278 2.9E-26 T 29-03-2018 IPR023214 HAD-like domain CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 SMART SM00831 626 700 4.1E-12 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 Pfam PF00122 E1-E2 ATPase 735 926 2.5E-49 T 29-03-2018 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 Gene3D G3DSA:3.40.50.1000 915 1000 3.0E-12 T 29-03-2018 IPR023214 HAD-like domain CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 Pfam PF00689 Cation transporting ATPase, C-terminus 1336 1494 7.5E-31 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 Gene3D G3DSA:3.40.1110.10 339 453 2.0E-10 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 Gene3D G3DSA:2.70.150.10 635 848 4.6E-42 T 29-03-2018 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 SUPERFAMILY SSF81653 736 845 6.67E-29 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 SUPERFAMILY SSF81665 626 738 2.75E-91 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 SUPERFAMILY SSF81665 1302 1494 2.75E-91 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 SUPERFAMILY SSF81665 847 940 2.75E-91 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS14355 e963b48f8d9efb04c51252052d22ead9 1518 SUPERFAMILY SSF81660 953 1154 2.18E-49 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS19440 2ee5f13853fa13bc292d749ceb8a4bea 228 Gene3D G3DSA:3.30.70.580 58 137 1.6E-16 T 29-03-2018 CB4_RS19440 2ee5f13853fa13bc292d749ceb8a4bea 228 Gene3D G3DSA:3.10.290.10 1 57 3.5E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS19440 2ee5f13853fa13bc292d749ceb8a4bea 228 Gene3D G3DSA:3.30.70.1560 138 204 2.0E-26 T 29-03-2018 CB4_RS19440 2ee5f13853fa13bc292d749ceb8a4bea 228 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 96 110 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CB4_RS19440 2ee5f13853fa13bc292d749ceb8a4bea 228 SUPERFAMILY SSF55120 60 221 6.96E-41 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS19440 2ee5f13853fa13bc292d749ceb8a4bea 228 SMART SM00363 1 59 1.7E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS19440 2ee5f13853fa13bc292d749ceb8a4bea 228 Pfam PF01479 S4 domain 1 46 1.2E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS19440 2ee5f13853fa13bc292d749ceb8a4bea 228 Pfam PF00849 RNA pseudouridylate synthase 61 187 7.6E-16 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS19440 2ee5f13853fa13bc292d749ceb8a4bea 228 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 217 1.4E-47 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CB4_RS19440 2ee5f13853fa13bc292d749ceb8a4bea 228 SUPERFAMILY SSF55174 1 53 2.36E-13 T 29-03-2018 CB4_RS17075 3023c0d80befdcdd74c0be9f1369a6ef 401 Gene3D G3DSA:3.30.70.1510 5 82 1.6E-26 T 29-03-2018 CB4_RS17075 3023c0d80befdcdd74c0be9f1369a6ef 401 Gene3D G3DSA:3.30.2300.10 87 165 2.4E-21 T 29-03-2018 CB4_RS17075 3023c0d80befdcdd74c0be9f1369a6ef 401 SUPERFAMILY SSF143437 3 175 1.26E-52 T 29-03-2018 CB4_RS17075 3023c0d80befdcdd74c0be9f1369a6ef 401 Pfam PF02926 THUMP domain 40 166 2.1E-23 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CB4_RS17075 3023c0d80befdcdd74c0be9f1369a6ef 401 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 377 6.3E-120 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CB4_RS17075 3023c0d80befdcdd74c0be9f1369a6ef 401 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 401 162.743 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CB4_RS17075 3023c0d80befdcdd74c0be9f1369a6ef 401 SUPERFAMILY SSF52402 177 389 9.04E-56 T 29-03-2018 CB4_RS17075 3023c0d80befdcdd74c0be9f1369a6ef 401 SMART SM00981 75 167 7.3E-23 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CB4_RS17075 3023c0d80befdcdd74c0be9f1369a6ef 401 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 366 7.5E-68 T 29-03-2018 IPR020536 Thil, AANH domain GO:0004810 CB4_RS17075 3023c0d80befdcdd74c0be9f1369a6ef 401 Gene3D G3DSA:3.40.50.620 177 399 5.0E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS09825 7f0172b846e9b34caa469ebe74d86993 231 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 203 2.1E-79 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CB4_RS09825 7f0172b846e9b34caa469ebe74d86993 231 SUPERFAMILY SSF50891 89 219 2.96E-51 T 29-03-2018 IPR029000 Cyclophilin-like domain CB4_RS09825 7f0172b846e9b34caa469ebe74d86993 231 Gene3D G3DSA:2.40.100.10 87 221 3.1E-55 T 29-03-2018 IPR029000 Cyclophilin-like domain CB4_RS09825 7f0172b846e9b34caa469ebe74d86993 231 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 211 6.7E-79 T 29-03-2018 IPR010016 KipI family CB4_RS09825 7f0172b846e9b34caa469ebe74d86993 231 SUPERFAMILY SSF160467 2 94 5.1E-18 T 29-03-2018 CB4_RS09825 7f0172b846e9b34caa469ebe74d86993 231 Gene3D G3DSA:3.30.1360.40 1 83 1.2E-21 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CB4_RS09825 7f0172b846e9b34caa469ebe74d86993 231 SMART SM00796 1 203 6.7E-104 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CB4_RS09755 5428e041db42cdbbac8b4c6a7d1c76f1 494 Gene3D G3DSA:3.90.1150.10 396 491 1.1E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS09755 5428e041db42cdbbac8b4c6a7d1c76f1 494 SMART SM00345 17 76 3.5E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS09755 5428e041db42cdbbac8b4c6a7d1c76f1 494 Gene3D G3DSA:1.10.10.10 2 78 4.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09755 5428e041db42cdbbac8b4c6a7d1c76f1 494 Gene3D G3DSA:3.40.640.10 143 395 2.2E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS09755 5428e041db42cdbbac8b4c6a7d1c76f1 494 Pfam PF00155 Aminotransferase class I and II 143 483 4.2E-26 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS09755 5428e041db42cdbbac8b4c6a7d1c76f1 494 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 5.6E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS09755 5428e041db42cdbbac8b4c6a7d1c76f1 494 SUPERFAMILY SSF46785 7 79 1.49E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09755 5428e041db42cdbbac8b4c6a7d1c76f1 494 SUPERFAMILY SSF53383 123 490 1.85E-76 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS16295 91970aee420024a26a5c9439554c05e3 295 SUPERFAMILY SSF56349 2 288 2.77E-58 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS16295 91970aee420024a26a5c9439554c05e3 295 Gene3D G3DSA:1.10.150.130 1 109 6.8E-24 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CB4_RS16295 91970aee420024a26a5c9439554c05e3 295 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 295 58.314 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CB4_RS16295 91970aee420024a26a5c9439554c05e3 295 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 295 8.1E-123 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CB4_RS16295 91970aee420024a26a5c9439554c05e3 295 Gene3D G3DSA:1.10.443.10 110 289 4.1E-49 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS16295 91970aee420024a26a5c9439554c05e3 295 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 88 3.4E-19 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CB4_RS16295 91970aee420024a26a5c9439554c05e3 295 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 295 60.765 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CB4_RS16295 91970aee420024a26a5c9439554c05e3 295 Pfam PF00589 Phage integrase family 110 281 8.0E-53 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS08520 a019485521a95a1071e30ccf9a3a5cd2 222 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 202 3.0E-85 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CB4_RS08520 a019485521a95a1071e30ccf9a3a5cd2 222 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CB4_RS08520 a019485521a95a1071e30ccf9a3a5cd2 222 PIRSF PIRSF001461 1 222 4.2E-95 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CB4_RS08520 a019485521a95a1071e30ccf9a3a5cd2 222 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 215 3.1E-91 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CB4_RS08520 a019485521a95a1071e30ccf9a3a5cd2 222 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CB4_RS08520 a019485521a95a1071e30ccf9a3a5cd2 222 Gene3D G3DSA:3.20.20.70 1 219 1.4E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS08520 a019485521a95a1071e30ccf9a3a5cd2 222 SUPERFAMILY SSF51366 1 215 4.44E-70 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CB4_RS11095 ad2f015850311d45c9942805975bd5a2 324 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 147 308 2.1E-54 T 29-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal CB4_RS11095 ad2f015850311d45c9942805975bd5a2 324 Pfam PF06081 Aromatic acid exporter family member 1 1 141 4.1E-48 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 CB4_RS12945 ca55e4ad816cc0d535cf79d2a21d3f03 323 SUPERFAMILY SSF47823 25 123 2.35E-31 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CB4_RS12945 ca55e4ad816cc0d535cf79d2a21d3f03 323 Gene3D G3DSA:1.10.150.130 19 126 8.7E-14 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CB4_RS12945 ca55e4ad816cc0d535cf79d2a21d3f03 323 Gene3D G3DSA:1.10.443.10 127 310 3.1E-28 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS12945 ca55e4ad816cc0d535cf79d2a21d3f03 323 SUPERFAMILY SSF56349 127 308 1.06E-38 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS12945 ca55e4ad816cc0d535cf79d2a21d3f03 323 Pfam PF00589 Phage integrase family 140 307 1.8E-16 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS12085 b89671e56142628cfa79d7b16cd72b79 299 SMART SM00859 5 118 1.9E-5 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CB4_RS12085 b89671e56142628cfa79d7b16cd72b79 299 PIRSF PIRSF015689 1 293 9.3E-136 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CB4_RS12085 b89671e56142628cfa79d7b16cd72b79 299 Gene3D G3DSA:3.40.50.720 4 139 1.4E-13 T 29-03-2018 CB4_RS12085 b89671e56142628cfa79d7b16cd72b79 299 SUPERFAMILY SSF55347 126 262 3.01E-62 T 29-03-2018 CB4_RS12085 b89671e56142628cfa79d7b16cd72b79 299 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 126 262 1.4E-65 T 29-03-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CB4_RS12085 b89671e56142628cfa79d7b16cd72b79 299 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 3 287 4.8E-143 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CB4_RS12085 b89671e56142628cfa79d7b16cd72b79 299 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 102 1.0E-9 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CB4_RS12085 b89671e56142628cfa79d7b16cd72b79 299 Gene3D G3DSA:3.30.360.10 140 262 1.8E-66 T 29-03-2018 CB4_RS12085 b89671e56142628cfa79d7b16cd72b79 299 SUPERFAMILY SSF51735 3 150 1.4E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS12085 b89671e56142628cfa79d7b16cd72b79 299 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 299 128.718 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 Gene3D G3DSA:3.30.1360.120 132 236 2.2E-30 T 29-03-2018 CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 267 357 9.4E-30 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 259 2.7E-93 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 PIRSF PIRSF006487 1 366 3.1E-100 T 29-03-2018 CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 Gene3D G3DSA:3.30.1360.120 4 131 3.5E-32 T 29-03-2018 CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 Gene3D G3DSA:2.40.30.110 282 366 8.7E-29 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 363 1.0E-141 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 363 47.932 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 SUPERFAMILY SSF103025 3 282 6.59E-96 T 29-03-2018 CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 SUPERFAMILY SSF101790 275 364 1.29E-27 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CB4_RS07695 041f9a77316fbfb4ccbc6a4840713233 366 Gene3D G3DSA:4.10.1250.10 239 279 3.1E-17 T 29-03-2018 CB4_RS16355 5032a54a680af283ab329e24c64747c5 515 Gene3D G3DSA:3.90.226.10 242 510 1.2E-77 T 29-03-2018 CB4_RS16355 5032a54a680af283ab329e24c64747c5 515 SUPERFAMILY SSF52096 269 515 6.69E-91 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS16355 5032a54a680af283ab329e24c64747c5 515 Gene3D G3DSA:3.90.226.10 1 241 1.7E-82 T 29-03-2018 CB4_RS16355 5032a54a680af283ab329e24c64747c5 515 SUPERFAMILY SSF52096 1 254 7.54E-81 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS16355 5032a54a680af283ab329e24c64747c5 515 Pfam PF01039 Carboxyl transferase domain 27 513 1.2E-195 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CB4_RS08555 cfe24962e8bcbb83e6879d127c64c690 171 Pfam PF02308 MgtC family 25 152 2.2E-28 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CB4_RS08555 cfe24962e8bcbb83e6879d127c64c690 171 PRINTS PR01837 MgtC/SapB protein signature 107 131 1.8E-34 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CB4_RS08555 cfe24962e8bcbb83e6879d127c64c690 171 PRINTS PR01837 MgtC/SapB protein signature 46 64 1.8E-34 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CB4_RS08555 cfe24962e8bcbb83e6879d127c64c690 171 PRINTS PR01837 MgtC/SapB protein signature 80 102 1.8E-34 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CB4_RS08555 cfe24962e8bcbb83e6879d127c64c690 171 PRINTS PR01837 MgtC/SapB protein signature 27 46 1.8E-34 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CB4_RS08575 b47982284cc4a0aa707dee3806bf6d40 266 Gene3D G3DSA:3.40.1090.10 1 258 6.4E-43 T 29-03-2018 CB4_RS08575 b47982284cc4a0aa707dee3806bf6d40 266 SUPERFAMILY SSF52151 11 257 6.28E-53 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CB4_RS08575 b47982284cc4a0aa707dee3806bf6d40 266 Pfam PF01734 Patatin-like phospholipase 13 170 4.9E-20 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CB4_RS14475 8a8ee3f00ba403b750ebb261c7d860b8 138 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 131 2.5E-15 T 29-03-2018 IPR028973 PhnB-like CB4_RS14475 8a8ee3f00ba403b750ebb261c7d860b8 138 Gene3D G3DSA:3.10.180.10 1 138 5.0E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS14475 8a8ee3f00ba403b750ebb261c7d860b8 138 SUPERFAMILY SSF54593 4 135 2.02E-33 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS18935 f85b828a0ef1b18abcb60f7c5f6f89d8 144 Gene3D G3DSA:3.30.420.10 1 144 1.4E-48 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS18935 f85b828a0ef1b18abcb60f7c5f6f89d8 144 Pfam PF00075 RNase H 2 141 1.4E-41 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CB4_RS18935 f85b828a0ef1b18abcb60f7c5f6f89d8 144 Hamap MF_00042 Ribonuclease H [rnhA]. 1 144 28.485 T 29-03-2018 IPR022892 Ribonuclease HI GO:0004523 CB4_RS18935 f85b828a0ef1b18abcb60f7c5f6f89d8 144 SUPERFAMILY SSF53098 1 142 4.43E-53 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 SUPERFAMILY SSF52518 16 202 4.24E-66 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 Gene3D G3DSA:3.40.50.1220 217 365 1.9E-49 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 24 189 1.6E-58 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 213 347 1.2E-44 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 Gene3D G3DSA:3.40.50.970 18 216 1.8E-64 T 29-03-2018 CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 SUPERFAMILY SSF52518 383 578 1.27E-72 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 Gene3D G3DSA:3.40.50.970 366 575 2.3E-57 T 29-03-2018 CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 24 576 5.6E-250 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 406 553 1.4E-51 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 443 462 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CB4_RS05305 5c06f92888d3bfdf7eca82a423afd135 581 SUPERFAMILY SSF52467 205 372 5.58E-56 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CB4_RS14615 c917cde12d924272aa84bf395c02313e 55 Pfam PF13518 Helix-turn-helix domain 9 47 5.7E-8 T 29-03-2018 CB4_RS14615 c917cde12d924272aa84bf395c02313e 55 Gene3D G3DSA:1.10.10.10 1 53 4.7E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14615 c917cde12d924272aa84bf395c02313e 55 SUPERFAMILY SSF46689 1 52 1.0E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS07225 df4d743dec6c347431c4d81c9b3c26ea 101 Gene3D G3DSA:3.40.1440.10 1 82 2.1E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS07225 df4d743dec6c347431c4d81c9b3c26ea 101 Pfam PF01541 GIY-YIG catalytic domain 1 73 5.8E-17 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS07225 df4d743dec6c347431c4d81c9b3c26ea 101 SUPERFAMILY SSF82771 1 72 1.19E-14 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS20365 d5e1723e668ba970d51be3d8e5b9d3d6 474 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 15 460 47.931 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CB4_RS20365 d5e1723e668ba970d51be3d8e5b9d3d6 474 SUPERFAMILY SSF53271 250 468 2.1E-72 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CB4_RS20365 d5e1723e668ba970d51be3d8e5b9d3d6 474 PIRSF PIRSF000485 12 474 4.6E-183 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CB4_RS20365 d5e1723e668ba970d51be3d8e5b9d3d6 474 Gene3D G3DSA:3.40.50.2020 242 442 2.4E-32 T 29-03-2018 CB4_RS20365 d5e1723e668ba970d51be3d8e5b9d3d6 474 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 16 461 3.0E-167 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CB4_RS20365 d5e1723e668ba970d51be3d8e5b9d3d6 474 SUPERFAMILY SSF56235 16 256 1.2E-71 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS20365 d5e1723e668ba970d51be3d8e5b9d3d6 474 Gene3D G3DSA:3.60.20.10 16 241 3.0E-62 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS20365 d5e1723e668ba970d51be3d8e5b9d3d6 474 Pfam PF13522 Glutamine amidotransferase domain 78 208 1.2E-21 T 29-03-2018 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 3.4E-69 T 29-03-2018 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 PRINTS PR00145 Argininosuccinate lyase family signature 275 291 3.4E-69 T 29-03-2018 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 PRINTS PR00145 Argininosuccinate lyase family signature 310 329 3.4E-69 T 29-03-2018 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 PRINTS PR00145 Argininosuccinate lyase family signature 193 209 3.4E-69 T 29-03-2018 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 3.4E-69 T 29-03-2018 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 PRINTS PR00145 Argininosuccinate lyase family signature 231 255 3.4E-69 T 29-03-2018 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 Gene3D G3DSA:1.10.275.10 2 106 1.8E-38 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 Pfam PF00206 Lyase 6 300 2.1E-78 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 Gene3D G3DSA:1.20.200.10 107 374 2.0E-97 T 29-03-2018 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 2.5E-29 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 PRINTS PR00149 Fumarate lyase superfamily signature 275 291 2.5E-29 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 2.5E-29 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 2.5E-29 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 452 7.2E-206 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 SUPERFAMILY SSF48557 3 451 2.04E-155 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 Gene3D G3DSA:1.10.40.30 375 432 5.2E-25 T 29-03-2018 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 453 44.227 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 Pfam PF14698 Argininosuccinate lyase C-terminal 363 431 3.8E-25 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03590 400754cb0f155d849e4ddebc6205cb5e 474 ProSitePatterns PS00163 Fumarate lyases signature. 275 284 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CB4_RS00045 87a2cea84573de83010660cc24403038 869 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CB4_RS00045 87a2cea84573de83010660cc24403038 869 SMART SM00382 203 349 1.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS00045 87a2cea84573de83010660cc24403038 869 SMART SM00382 605 758 1.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS00045 87a2cea84573de83010660cc24403038 869 Gene3D G3DSA:3.40.50.300 162 347 1.6E-25 T 29-03-2018 CB4_RS00045 87a2cea84573de83010660cc24403038 869 SUPERFAMILY SSF81923 4 161 4.05E-38 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CB4_RS00045 87a2cea84573de83010660cc24403038 869 Pfam PF07724 AAA domain (Cdc48 subfamily) 604 770 1.7E-56 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS00045 87a2cea84573de83010660cc24403038 869 Gene3D G3DSA:1.10.1780.10 1 156 2.2E-37 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CB4_RS00045 87a2cea84573de83010660cc24403038 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 609 627 1.3E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS00045 87a2cea84573de83010660cc24403038 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 683 701 1.3E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS00045 87a2cea84573de83010660cc24403038 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 716 730 1.3E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS00045 87a2cea84573de83010660cc24403038 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 672 1.3E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS00045 87a2cea84573de83010660cc24403038 869 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 208 325 1.8E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS00045 87a2cea84573de83010660cc24403038 869 Gene3D G3DSA:1.10.8.60 776 869 1.9E-22 T 29-03-2018 CB4_RS00045 87a2cea84573de83010660cc24403038 869 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 639 657 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CB4_RS00045 87a2cea84573de83010660cc24403038 869 Gene3D G3DSA:1.10.8.60 348 555 1.8E-44 T 29-03-2018 CB4_RS00045 87a2cea84573de83010660cc24403038 869 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 776 856 1.0E-24 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CB4_RS00045 87a2cea84573de83010660cc24403038 869 SMART SM01086 776 865 4.7E-33 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CB4_RS00045 87a2cea84573de83010660cc24403038 869 SUPERFAMILY SSF52540 162 553 8.56E-97 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00045 87a2cea84573de83010660cc24403038 869 SUPERFAMILY SSF52540 554 854 3.76E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00045 87a2cea84573de83010660cc24403038 869 Gene3D G3DSA:3.40.50.300 560 775 7.4E-56 T 29-03-2018 CB4_RS00045 87a2cea84573de83010660cc24403038 869 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 865 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CB4_RS00045 87a2cea84573de83010660cc24403038 869 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 150 7.9E-10 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CB4_RS00045 87a2cea84573de83010660cc24403038 869 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 2.8E-13 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 SMART SM00316 618 688 1.4E-25 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 SUPERFAMILY SSF54211 6 143 1.87E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 318 1.5E-15 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 691 31.039 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Pfam PF03725 3' exoribonuclease family, domain 2 146 209 8.0E-13 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Pfam PF03725 3' exoribonuclease family, domain 2 457 526 6.0E-8 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Gene3D G3DSA:1.10.10.400 251 309 1.6E-23 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Gene3D G3DSA:3.30.1370.10 553 623 1.0E-13 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Pfam PF01138 3' exoribonuclease family, domain 1 321 454 1.8E-17 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Pfam PF01138 3' exoribonuclease family, domain 1 13 143 4.6E-21 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 SUPERFAMILY SSF55666 144 234 3.23E-29 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 SUPERFAMILY SSF54211 290 486 5.06E-50 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 SUPERFAMILY SSF54791 553 638 6.07E-24 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 SMART SM00322 550 615 3.1E-11 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Gene3D G3DSA:3.30.230.70 310 552 3.8E-59 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 SUPERFAMILY SSF55666 448 547 4.58E-28 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 PIRSF PIRSF005499 1 704 1.5E-299 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Gene3D G3DSA:3.30.230.70 11 250 4.7E-57 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Pfam PF00013 KH domain 555 611 2.5E-8 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 SUPERFAMILY SSF50249 618 696 2.91E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Pfam PF00575 S1 RNA binding domain 617 688 1.0E-19 T 29-03-2018 IPR003029 S1 domain GO:0003676 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 Gene3D G3DSA:2.40.50.140 624 694 3.0E-23 T 29-03-2018 CB4_RS09360 b793d2e03c45720c82e1a9eccbfcd9d4 704 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 689 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CB4_RS01295 49c7d3f58b009596cd3137bffffdd940 447 Pfam PF00672 HAMP domain 89 138 8.0E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS01295 49c7d3f58b009596cd3137bffffdd940 447 Gene3D G3DSA:1.10.287.950 383 443 1.6E-5 T 29-03-2018 CB4_RS01295 49c7d3f58b009596cd3137bffffdd940 447 Gene3D G3DSA:1.10.287.950 197 382 5.8E-48 T 29-03-2018 CB4_RS01295 49c7d3f58b009596cd3137bffffdd940 447 SUPERFAMILY SSF58104 114 144 7.19E-71 T 29-03-2018 CB4_RS01295 49c7d3f58b009596cd3137bffffdd940 447 SUPERFAMILY SSF58104 177 446 7.19E-71 T 29-03-2018 CB4_RS01295 49c7d3f58b009596cd3137bffffdd940 447 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 116 442 0.008 T 29-03-2018 CB4_RS01295 49c7d3f58b009596cd3137bffffdd940 447 Gene3D G3DSA:1.10.287.950 5 196 1.6E-11 T 29-03-2018 CB4_RS01295 49c7d3f58b009596cd3137bffffdd940 447 SMART SM00304 89 142 5.7E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS01295 49c7d3f58b009596cd3137bffffdd940 447 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 216 399 3.1E-45 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS01295 49c7d3f58b009596cd3137bffffdd940 447 SMART SM00283 171 446 2.6E-75 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 Gene3D G3DSA:3.30.565.10 388 531 1.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 SUPERFAMILY SSF103190 38 167 4.32E-30 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 Pfam PF00989 PAS fold 215 274 1.2E-5 T 29-03-2018 IPR013767 PAS fold GO:0006355 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 Gene3D G3DSA:3.30.450.20 37 159 6.8E-19 T 29-03-2018 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 SMART SM00091 212 277 4.5E-5 T 29-03-2018 IPR000014 PAS domain CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 Pfam PF17203 Single cache domain 3 40 163 5.9E-20 T 29-03-2018 IPR033463 Single cache domain 3 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 SUPERFAMILY SSF55785 215 287 2.72E-8 T 29-03-2018 IPR000014 PAS domain CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 SMART SM00387 416 527 5.6E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 485 7.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 7.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 471 7.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 7.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 Gene3D G3DSA:3.30.450.20 199 315 1.7E-10 T 29-03-2018 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 421 526 1.7E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 SUPERFAMILY SSF55874 393 524 1.83E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 SUPERFAMILY SSF55890 319 370 8.5E-11 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 Gene3D G3DSA:1.10.287.130 316 373 2.0E-17 T 29-03-2018 CB4_RS06715 4590b8bc3676a8e16ac586dbb71557ef 531 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 319 369 1.2E-8 T 29-03-2018 CB4_RS04940 3e69494755281794634376049976b21f 173 Pfam PF14172 Domain of unknown function (DUF4309) 44 168 1.4E-14 T 29-03-2018 IPR025453 Protein of unknown function DUF4309 CB4_RS09065 512a7b88e60742d9eb49e0e25475987c 465 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 357 427 2.4E-7 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CB4_RS09065 512a7b88e60742d9eb49e0e25475987c 465 Gene3D G3DSA:1.10.8.60 372 453 9.3E-31 T 29-03-2018 CB4_RS09065 512a7b88e60742d9eb49e0e25475987c 465 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 8 465 2.7E-205 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CB4_RS09065 512a7b88e60742d9eb49e0e25475987c 465 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 56 115 1.1E-6 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS09065 512a7b88e60742d9eb49e0e25475987c 465 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 4 465 42.967 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CB4_RS09065 512a7b88e60742d9eb49e0e25475987c 465 Gene3D G3DSA:3.40.50.300 2 371 7.0E-52 T 29-03-2018 CB4_RS09065 512a7b88e60742d9eb49e0e25475987c 465 SMART SM00382 52 354 6.4E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS09065 512a7b88e60742d9eb49e0e25475987c 465 SUPERFAMILY SSF52540 5 463 1.58E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09065 512a7b88e60742d9eb49e0e25475987c 465 Pfam PF07724 AAA domain (Cdc48 subfamily) 215 351 6.9E-38 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS09065 512a7b88e60742d9eb49e0e25475987c 465 SMART SM01086 357 451 1.3E-22 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CB4_RS10865 a49c9aa554786e53af44efe4e5659cb1 316 Pfam PF00248 Aldo/keto reductase family 15 314 7.8E-82 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CB4_RS10865 a49c9aa554786e53af44efe4e5659cb1 316 SUPERFAMILY SSF51430 2 315 3.14E-105 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CB4_RS10865 a49c9aa554786e53af44efe4e5659cb1 316 Gene3D G3DSA:3.20.20.100 3 316 2.0E-106 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CB4_RS10865 a49c9aa554786e53af44efe4e5659cb1 316 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 204 210 4.6E-6 T 29-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 CB4_RS10865 a49c9aa554786e53af44efe4e5659cb1 316 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 257 269 4.6E-6 T 29-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 CB4_RS10865 a49c9aa554786e53af44efe4e5659cb1 316 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 109 119 4.6E-6 T 29-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 CB4_RS10865 a49c9aa554786e53af44efe4e5659cb1 316 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 270 283 4.6E-6 T 29-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 Pfam PF03572 Peptidase family S41 216 375 6.8E-48 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 114 181 1.1E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 71 391 4.2E-112 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 SUPERFAMILY SSF52096 209 381 2.65E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 SUPERFAMILY SSF52096 53 132 2.65E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 SUPERFAMILY SSF47090 392 457 1.46E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 Gene3D G3DSA:2.30.42.10 114 194 2.3E-20 T 29-03-2018 CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 SUPERFAMILY SSF50156 87 205 2.8E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 SMART SM00228 114 185 2.2E-19 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 Pfam PF01471 Putative peptidoglycan binding domain 398 453 1.7E-14 T 29-03-2018 IPR002477 Peptidoglycan binding-like CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 Gene3D G3DSA:3.30.750.44 37 113 4.5E-14 T 29-03-2018 CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 Gene3D G3DSA:1.10.101.10 389 464 1.4E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 SMART SM00245 187 376 2.0E-64 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CB4_RS03610 e3a152da2c86b87a29cb4de45e43f95d 482 Gene3D G3DSA:3.90.226.10 195 388 1.2E-55 T 29-03-2018 CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 229 249 3.5E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 37 63 3.5E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 275 301 3.5E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 8 24 3.5E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 198 223 3.5E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 117 140 3.5E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 251 271 3.5E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 Pfam PF14841 FliG middle domain 118 191 1.4E-30 T 29-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 Gene3D G3DSA:1.10.220.30 86 196 3.3E-21 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 Gene3D G3DSA:1.10.220.30 198 337 1.3E-37 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 Gene3D G3DSA:1.10.220.30 5 85 4.2E-16 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 SUPERFAMILY SSF48029 9 104 1.96E-22 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 PIRSF PIRSF003161 2 337 3.5E-121 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 SUPERFAMILY SSF48029 117 328 2.75E-69 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 4 337 7.5E-144 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 Pfam PF01706 FliG C-terminal domain 221 327 3.3E-43 T 29-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal CB4_RS09095 48c196786ec8c5a5dbb3a0f5d674b192 337 Pfam PF14842 FliG N-terminal domain 7 110 3.5E-38 T 29-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 Pfam PF13432 Tetratricopeptide repeat 147 188 0.0021 T 29-03-2018 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 Pfam PF13432 Tetratricopeptide repeat 201 258 9.4E-6 T 29-03-2018 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 SUPERFAMILY SSF48452 103 290 2.02E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 Gene3D G3DSA:1.20.58.280 150 177 1.3E-4 T 29-03-2018 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 Gene3D G3DSA:1.25.40.10 214 254 3.1E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 Gene3D G3DSA:1.25.40.10 178 213 1.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 Gene3D G3DSA:1.25.40.10 16 149 8.5E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 Pfam PF13176 Tetratricopeptide repeat 268 297 0.0048 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 Gene3D G3DSA:1.25.20.10 313 375 9.8E-8 T 29-03-2018 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 SMART SM00028 263 296 41.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 SMART SM00028 163 196 230.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 SMART SM00028 129 162 0.12 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 SMART SM00028 229 262 1.4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 SMART SM00028 331 364 24.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 Pfam PF13181 Tetratricopeptide repeat 333 357 0.16 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 SUPERFAMILY SSF48452 280 363 3.16E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS15055 cdb140e621972c33b24621dd02eb7463 379 Gene3D G3DSA:1.25.40.10 255 312 5.4E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS20180 362dbcc9a44bc2468b0dba4123d93df0 194 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CB4_RS20180 362dbcc9a44bc2468b0dba4123d93df0 194 SMART SM00072 7 174 5.5E-9 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CB4_RS20180 362dbcc9a44bc2468b0dba4123d93df0 194 Pfam PF00625 Guanylate kinase 10 177 6.8E-24 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CB4_RS20180 362dbcc9a44bc2468b0dba4123d93df0 194 Gene3D G3DSA:3.40.50.300 3 187 7.8E-37 T 29-03-2018 CB4_RS20180 362dbcc9a44bc2468b0dba4123d93df0 194 SUPERFAMILY SSF52540 7 185 5.74E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05225 63c9d9a3fe672a8eb7705519abd5d431 527 Pfam PF00990 Diguanylate cyclase, GGDEF domain 365 514 2.9E-43 T 29-03-2018 IPR000160 GGDEF domain CB4_RS05225 63c9d9a3fe672a8eb7705519abd5d431 527 SUPERFAMILY SSF103190 185 261 2.35E-11 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS05225 63c9d9a3fe672a8eb7705519abd5d431 527 SUPERFAMILY SSF103190 64 175 7.59E-11 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS05225 63c9d9a3fe672a8eb7705519abd5d431 527 SMART SM00267 350 518 7.7E-52 T 29-03-2018 IPR000160 GGDEF domain CB4_RS05225 63c9d9a3fe672a8eb7705519abd5d431 527 SUPERFAMILY SSF55073 369 519 1.88E-44 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS05225 63c9d9a3fe672a8eb7705519abd5d431 527 Gene3D G3DSA:3.30.70.270 355 519 1.8E-49 T 29-03-2018 CB4_RS05225 63c9d9a3fe672a8eb7705519abd5d431 527 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 363 517 1.3E-47 T 29-03-2018 IPR000160 GGDEF domain CB4_RS05225 63c9d9a3fe672a8eb7705519abd5d431 527 Gene3D G3DSA:3.30.450.20 165 283 3.4E-22 T 29-03-2018 CB4_RS05225 63c9d9a3fe672a8eb7705519abd5d431 527 Pfam PF02743 Cache domain 48 266 6.4E-25 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS05225 63c9d9a3fe672a8eb7705519abd5d431 527 Gene3D G3DSA:3.30.450.20 81 164 4.7E-14 T 29-03-2018 CB4_RS12465 3e9e61410b2aac0b4955c9b1d2359d49 111 Gene3D G3DSA:1.10.10.10 2 111 3.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12465 3e9e61410b2aac0b4955c9b1d2359d49 111 Pfam PF03551 Transcriptional regulator PadR-like family 16 90 1.7E-25 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CB4_RS12465 3e9e61410b2aac0b4955c9b1d2359d49 111 SUPERFAMILY SSF46785 4 100 1.87E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS01365 116bc729d969096c194124087fe8f653 493 Gene3D G3DSA:3.60.120.10 49 493 4.8E-156 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CB4_RS01365 116bc729d969096c194124087fe8f653 493 PRINTS PR00095 Anthranilate synthase component I signature 337 350 1.3E-13 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS01365 116bc729d969096c194124087fe8f653 493 PRINTS PR00095 Anthranilate synthase component I signature 417 431 1.3E-13 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS01365 116bc729d969096c194124087fe8f653 493 PRINTS PR00095 Anthranilate synthase component I signature 432 446 1.3E-13 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS01365 116bc729d969096c194124087fe8f653 493 PRINTS PR00095 Anthranilate synthase component I signature 323 336 1.3E-13 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS01365 116bc729d969096c194124087fe8f653 493 Pfam PF04715 Anthranilate synthase component I, N terminal region 31 168 8.0E-31 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS01365 116bc729d969096c194124087fe8f653 493 Pfam PF00425 chorismate binding enzyme 222 475 9.1E-95 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CB4_RS01365 116bc729d969096c194124087fe8f653 493 SUPERFAMILY SSF56322 18 484 1.57E-144 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CB4_RS10580 77a955e4dedcd0027e567c80047f8a8f 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 1.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS10580 77a955e4dedcd0027e567c80047f8a8f 199 Gene3D G3DSA:1.10.10.60 3 56 1.3E-11 T 29-03-2018 CB4_RS10580 77a955e4dedcd0027e567c80047f8a8f 199 SUPERFAMILY SSF48498 89 196 1.45E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS10580 77a955e4dedcd0027e567c80047f8a8f 199 Gene3D G3DSA:1.10.357.10 57 199 2.3E-12 T 29-03-2018 CB4_RS10580 77a955e4dedcd0027e567c80047f8a8f 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 5.7E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS10580 77a955e4dedcd0027e567c80047f8a8f 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 5.7E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS10580 77a955e4dedcd0027e567c80047f8a8f 199 SUPERFAMILY SSF46689 5 75 5.13E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS09580 c40025d2e57a59140723f49a05672cc5 109 Pfam PF01588 Putative tRNA binding domain 12 106 1.4E-16 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CB4_RS09580 c40025d2e57a59140723f49a05672cc5 109 SUPERFAMILY SSF50249 2 108 1.54E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS09580 c40025d2e57a59140723f49a05672cc5 109 Gene3D G3DSA:2.40.50.140 1 109 7.4E-20 T 29-03-2018 CB4_RS09580 c40025d2e57a59140723f49a05672cc5 109 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 4 108 1.1E-47 T 29-03-2018 IPR008231 Probable chaperone CsaA CB4_RS12870 e2503346248a644433b4ae5fb822ee44 166 Gene3D G3DSA:3.40.430.10 1 164 2.9E-55 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CB4_RS12870 e2503346248a644433b4ae5fb822ee44 166 PIRSF PIRSF000194 1 163 1.6E-56 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS12870 e2503346248a644433b4ae5fb822ee44 166 SUPERFAMILY SSF53597 1 160 1.15E-56 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CB4_RS12870 e2503346248a644433b4ae5fb822ee44 166 Pfam PF00186 Dihydrofolate reductase 1 160 5.6E-59 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS12870 e2503346248a644433b4ae5fb822ee44 166 PRINTS PR00070 Dihydrofolate reductase signature 13 23 2.3E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS12870 e2503346248a644433b4ae5fb822ee44 166 PRINTS PR00070 Dihydrofolate reductase signature 27 35 2.3E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS12870 e2503346248a644433b4ae5fb822ee44 166 PRINTS PR00070 Dihydrofolate reductase signature 94 108 2.3E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS12870 e2503346248a644433b4ae5fb822ee44 166 PRINTS PR00070 Dihydrofolate reductase signature 40 51 2.3E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS04905 a15afe1376d0772f12172fe443e006fa 496 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 6.4E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS04905 a15afe1376d0772f12172fe443e006fa 496 SMART SM00345 17 76 2.5E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS04905 a15afe1376d0772f12172fe443e006fa 496 Gene3D G3DSA:1.10.10.10 4 77 9.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04905 a15afe1376d0772f12172fe443e006fa 496 SUPERFAMILY SSF46785 6 80 2.14E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04905 a15afe1376d0772f12172fe443e006fa 496 Gene3D G3DSA:3.90.1150.10 361 484 3.2E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS04905 a15afe1376d0772f12172fe443e006fa 496 Gene3D G3DSA:3.40.640.10 154 360 3.5E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS04905 a15afe1376d0772f12172fe443e006fa 496 SUPERFAMILY SSF53383 120 481 1.21E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS04905 a15afe1376d0772f12172fe443e006fa 496 Pfam PF00155 Aminotransferase class I and II 151 474 1.2E-38 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS04365 fab2ca479d7cc8d320fa2b7b3c7628ac 214 Pfam PF08486 Stage II sporulation protein 64 143 1.8E-9 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 SUPERFAMILY SSF53901 270 391 2.02E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 390 9.3E-145 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 Gene3D G3DSA:3.40.47.10 265 389 1.5E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 PIRSF PIRSF000429 1 393 2.8E-133 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 Pfam PF02803 Thiolase, C-terminal domain 269 390 1.7E-48 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 Gene3D G3DSA:3.40.47.10 1 264 3.1E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 SUPERFAMILY SSF53901 1 265 1.05E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 Pfam PF00108 Thiolase, N-terminal domain 5 262 1.4E-76 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CB4_RS10410 e79f66cf702e2c2a52a14d65920c2e7c 393 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CB4_RS06705 82dae271b07e3f98961180e3234a4640 446 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 429 5.0E-146 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CB4_RS06705 82dae271b07e3f98961180e3234a4640 446 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CB4_RS06705 82dae271b07e3f98961180e3234a4640 446 SUPERFAMILY SSF102114 117 364 6.28E-59 T 29-03-2018 CB4_RS06705 82dae271b07e3f98961180e3234a4640 446 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 2.2E-26 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CB4_RS06705 82dae271b07e3f98961180e3234a4640 446 Gene3D G3DSA:3.80.30.20 140 375 2.0E-52 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CB4_RS06705 82dae271b07e3f98961180e3234a4640 446 SMART SM00729 143 361 4.4E-57 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS06705 82dae271b07e3f98961180e3234a4640 446 Pfam PF04055 Radical SAM superfamily 149 318 1.3E-28 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS06705 82dae271b07e3f98961180e3234a4640 446 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 423 3.9E-143 T 29-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 CB4_RS07955 9b3fa1174d4668d0ec00869eff47820d 144 Gene3D G3DSA:1.10.940.10 1 141 1.5E-48 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CB4_RS07955 9b3fa1174d4668d0ec00869eff47820d 144 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 138 25.0 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CB4_RS07955 9b3fa1174d4668d0ec00869eff47820d 144 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 136 3.6E-46 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CB4_RS07955 9b3fa1174d4668d0ec00869eff47820d 144 Pfam PF01029 NusB family 4 135 2.1E-40 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CB4_RS07955 9b3fa1174d4668d0ec00869eff47820d 144 SUPERFAMILY SSF48013 2 137 3.92E-41 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CB4_RS04600 9a7033083805135e318b9ec6b7c95eef 157 Pfam PF00583 Acetyltransferase (GNAT) family 56 141 1.7E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS04600 9a7033083805135e318b9ec6b7c95eef 157 SUPERFAMILY SSF55729 6 149 1.7E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS04600 9a7033083805135e318b9ec6b7c95eef 157 Gene3D G3DSA:3.40.630.30 2 154 2.2E-18 T 29-03-2018 CB4_RS10280 6042efea04b9d1a001e8428f61d8e247 858 SMART SM00382 537 713 0.0016 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS10280 6042efea04b9d1a001e8428f61d8e247 858 SMART SM00843 788 853 3.1E-38 T 29-03-2018 IPR018541 FtsK gamma domain CB4_RS10280 6042efea04b9d1a001e8428f61d8e247 858 SUPERFAMILY SSF52540 475 765 1.52E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10280 6042efea04b9d1a001e8428f61d8e247 858 SUPERFAMILY SSF46785 789 854 7.07E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS10280 6042efea04b9d1a001e8428f61d8e247 858 Pfam PF09397 Ftsk gamma domain 790 850 3.8E-29 T 29-03-2018 IPR018541 FtsK gamma domain CB4_RS10280 6042efea04b9d1a001e8428f61d8e247 858 Gene3D G3DSA:3.40.50.300 223 733 3.4E-53 T 29-03-2018 CB4_RS10280 6042efea04b9d1a001e8428f61d8e247 858 Gene3D G3DSA:1.10.10.10 790 844 1.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS10280 6042efea04b9d1a001e8428f61d8e247 858 Pfam PF01580 FtsK/SpoIIIE family 641 692 1.3E-16 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CB4_RS10280 6042efea04b9d1a001e8428f61d8e247 858 Pfam PF01580 FtsK/SpoIIIE family 502 638 7.8E-48 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CB4_RS01515 0f30cbc7688b060340be0d3904efc6d2 59 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 54 5.2E-8 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CB4_RS01515 0f30cbc7688b060340be0d3904efc6d2 59 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS16120 ae069aa6abaee6eac3d56d7df784321c 482 Pfam PF00171 Aldehyde dehydrogenase family 20 476 7.2E-164 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS16120 ae069aa6abaee6eac3d56d7df784321c 482 Gene3D G3DSA:3.40.605.10 1 265 1.5E-88 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS16120 ae069aa6abaee6eac3d56d7df784321c 482 SUPERFAMILY SSF53720 2 479 3.67E-159 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS16120 ae069aa6abaee6eac3d56d7df784321c 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CB4_RS16120 ae069aa6abaee6eac3d56d7df784321c 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CB4_RS16120 ae069aa6abaee6eac3d56d7df784321c 482 Gene3D G3DSA:3.40.309.10 266 460 1.3E-65 T 29-03-2018 CB4_RS10360 b03ec087b57f938b7d170aed048a16b4 289 Gene3D G3DSA:2.40.50.140 153 220 1.8E-10 T 29-03-2018 CB4_RS10360 b03ec087b57f938b7d170aed048a16b4 289 Gene3D G3DSA:2.40.50.140 1 63 6.1E-5 T 29-03-2018 CB4_RS10360 b03ec087b57f938b7d170aed048a16b4 289 SUPERFAMILY SSF50249 154 215 8.58E-8 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS10360 b03ec087b57f938b7d170aed048a16b4 289 PIRSF PIRSF012524 1 283 3.3E-94 T 29-03-2018 IPR014464 Conserved virulence factor B CB4_RS10360 b03ec087b57f938b7d170aed048a16b4 289 SMART SM00316 151 213 4.9E-4 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS10360 b03ec087b57f938b7d170aed048a16b4 289 SMART SM00316 4 73 0.61 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS10360 b03ec087b57f938b7d170aed048a16b4 289 Gene3D G3DSA:1.10.10.10 223 282 1.7E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS10360 b03ec087b57f938b7d170aed048a16b4 289 Pfam PF13509 S1 domain 6 63 4.0E-16 T 29-03-2018 CB4_RS10360 b03ec087b57f938b7d170aed048a16b4 289 Gene3D G3DSA:2.40.50.140 64 148 1.8E-4 T 29-03-2018 CB4_RS06665 ddfb52e1cdd6ff7da48dc1a0f82798e2 384 SUPERFAMILY SSF102114 3 378 1.83E-122 T 29-03-2018 CB4_RS06665 ddfb52e1cdd6ff7da48dc1a0f82798e2 384 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 363 3.4E-115 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CB4_RS06665 ddfb52e1cdd6ff7da48dc1a0f82798e2 384 SMART SM00729 2 224 3.9E-58 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS06665 ddfb52e1cdd6ff7da48dc1a0f82798e2 384 Pfam PF06969 HemN C-terminal domain 304 367 9.0E-13 T 29-03-2018 IPR010723 HemN, C-terminal CB4_RS06665 ddfb52e1cdd6ff7da48dc1a0f82798e2 384 Gene3D G3DSA:3.20.20.70 1 319 6.6E-50 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS06665 ddfb52e1cdd6ff7da48dc1a0f82798e2 384 Pfam PF04055 Radical SAM superfamily 7 178 9.6E-25 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS05360 e9aaa4919ca363da933b34ae828fae73 218 SUPERFAMILY SSF116726 132 216 6.93E-22 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CB4_RS05360 e9aaa4919ca363da933b34ae828fae73 218 Pfam PF02254 TrkA-N domain 6 121 2.0E-29 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CB4_RS05360 e9aaa4919ca363da933b34ae828fae73 218 Gene3D G3DSA:3.40.50.720 4 136 8.1E-25 T 29-03-2018 CB4_RS05360 e9aaa4919ca363da933b34ae828fae73 218 Gene3D G3DSA:3.30.70.1450 137 218 1.3E-21 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CB4_RS05360 e9aaa4919ca363da933b34ae828fae73 218 Pfam PF02080 TrkA-C domain 151 217 7.6E-14 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CB4_RS05360 e9aaa4919ca363da933b34ae828fae73 218 SUPERFAMILY SSF51735 5 137 2.79E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS14290 a762397cdb53b360136257a469daeb76 237 Pfam PF13462 Thioredoxin 55 220 1.6E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS14290 a762397cdb53b360136257a469daeb76 237 Gene3D G3DSA:3.40.30.10 55 237 1.3E-37 T 29-03-2018 CB4_RS14290 a762397cdb53b360136257a469daeb76 237 SUPERFAMILY SSF52833 49 219 1.12E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS20295 8cf60a1b61c9c2b86dac499177f455f3 157 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 29-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CB4_RS20295 8cf60a1b61c9c2b86dac499177f455f3 157 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 29-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CB4_RS20295 8cf60a1b61c9c2b86dac499177f455f3 157 PIRSF PIRSF000303 1 157 6.1E-69 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CB4_RS20295 8cf60a1b61c9c2b86dac499177f455f3 157 Gene3D G3DSA:3.40.30.10 1 157 1.3E-51 T 29-03-2018 CB4_RS20295 8cf60a1b61c9c2b86dac499177f455f3 157 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.7E-19 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CB4_RS20295 8cf60a1b61c9c2b86dac499177f455f3 157 PRINTS PR01011 Glutathione peroxidase family signature 121 130 1.7E-19 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CB4_RS20295 8cf60a1b61c9c2b86dac499177f455f3 157 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.7E-19 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CB4_RS20295 8cf60a1b61c9c2b86dac499177f455f3 157 SUPERFAMILY SSF52833 1 157 5.07E-64 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS20295 8cf60a1b61c9c2b86dac499177f455f3 157 Pfam PF00255 Glutathione peroxidase 3 109 4.5E-41 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 Pfam PF00702 haloacid dehalogenase-like hydrolase 493 710 7.5E-45 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 Gene3D G3DSA:3.40.1110.10 513 621 1.7E-32 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 268 775 1.5E-93 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 Gene3D G3DSA:1.20.1110.10 136 512 2.3E-46 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 499 505 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 SUPERFAMILY SSF55008 4 70 3.27E-20 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 227 798 1.1E-204 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 Gene3D G3DSA:3.30.70.100 1 72 1.0E-22 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00942 Copper-transporting ATPase 1 signature 31 54 1.6E-14 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00942 Copper-transporting ATPase 1 signature 210 235 1.6E-14 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00942 Copper-transporting ATPase 1 signature 5 30 1.6E-14 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 Pfam PF00403 Heavy-metal-associated domain 7 67 1.4E-16 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 Pfam PF00403 Heavy-metal-associated domain 76 135 3.1E-16 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 SUPERFAMILY SSF81665 745 766 1.7E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 SUPERFAMILY SSF81665 396 491 1.7E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 SUPERFAMILY SSF81665 261 299 1.7E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 719 731 2.7E-29 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 696 715 2.7E-29 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 497 511 2.7E-29 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 643 653 2.7E-29 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 621 632 2.7E-29 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 345 359 2.7E-29 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 SUPERFAMILY SSF81653 299 395 9.94E-31 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 208 799 3.2E-188 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 Pfam PF00122 E1-E2 ATPase 296 476 2.5E-59 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 Gene3D G3DSA:3.30.70.100 73 135 9.1E-24 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 ProSitePatterns PS01047 Heavy-metal-associated domain. 78 107 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 Gene3D G3DSA:3.40.50.1000 622 761 2.4E-45 T 29-03-2018 IPR023214 HAD-like domain CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 5 68 1.3E-11 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 74 137 5.5E-12 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 SUPERFAMILY SSF56784 495 515 3.09E-64 T 29-03-2018 IPR023214 HAD-like domain CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 SUPERFAMILY SSF56784 554 796 3.09E-64 T 29-03-2018 IPR023214 HAD-like domain CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 SUPERFAMILY SSF55008 73 141 1.06E-20 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00943 Copper-transporting ATPase signature 117 137 8.7E-19 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00943 Copper-transporting ATPase signature 88 102 8.7E-19 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00943 Copper-transporting ATPase signature 212 231 8.7E-19 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00943 Copper-transporting ATPase signature 480 495 8.7E-19 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00943 Copper-transporting ATPase signature 265 284 8.7E-19 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00943 Copper-transporting ATPase signature 673 690 8.7E-19 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00943 Copper-transporting ATPase signature 418 432 8.7E-19 T 29-03-2018 CB4_RS09960 3c1cc000d21f5a9e9192d865d2ddfead 804 PRINTS PR00943 Copper-transporting ATPase signature 285 303 8.7E-19 T 29-03-2018 CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 Pfam PF07694 5TMR of 5TMR-LYT 26 187 1.7E-9 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 SMART SM00388 206 272 4.3E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 SMART SM00387 313 419 1.2E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 SUPERFAMILY SSF55874 269 417 3.67E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 SUPERFAMILY SSF47384 199 271 3.53E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 417 1.5E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 Gene3D G3DSA:3.30.565.10 272 423 1.1E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 2.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 2.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 2.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 2.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 271 8.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS15735 90d2328ddfefe904be4cbb19a4811853 425 Gene3D G3DSA:1.10.287.130 194 268 1.4E-13 T 29-03-2018 CB4_RS20530 f9231e52f2a0248253889c0f5305eca5 116 PIRSF PIRSF033490 1 113 6.5E-38 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CB4_RS20530 f9231e52f2a0248253889c0f5305eca5 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 2.2E-33 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CB4_RS20530 f9231e52f2a0248253889c0f5305eca5 116 Gene3D G3DSA:2.30.30.110 1 116 2.2E-38 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CB4_RS20530 f9231e52f2a0248253889c0f5305eca5 116 SUPERFAMILY SSF50118 2 113 4.74E-41 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CB4_RS10895 5d1087fc2fd8b2f733c02833c27d9ef9 300 Pfam PF00892 EamA-like transporter family 150 282 2.0E-28 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS10895 5d1087fc2fd8b2f733c02833c27d9ef9 300 Pfam PF00892 EamA-like transporter family 3 134 2.5E-26 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS10895 5d1087fc2fd8b2f733c02833c27d9ef9 300 SUPERFAMILY SSF103481 36 138 1.7E-19 T 29-03-2018 CB4_RS10895 5d1087fc2fd8b2f733c02833c27d9ef9 300 SUPERFAMILY SSF103481 186 283 6.41E-16 T 29-03-2018 CB4_RS09040 c64afff0162d0a5fdef0bb12c0be80bf 368 Gene3D G3DSA:3.40.50.450 115 265 9.5E-39 T 29-03-2018 CB4_RS09040 c64afff0162d0a5fdef0bb12c0be80bf 368 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 74 286 1.1E-81 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CB4_RS09040 c64afff0162d0a5fdef0bb12c0be80bf 368 Pfam PF02481 DNA recombination-mediator protein A 74 280 1.8E-82 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CB4_RS09040 c64afff0162d0a5fdef0bb12c0be80bf 368 SUPERFAMILY SSF102405 83 286 2.29E-45 T 29-03-2018 CB4_RS12915 99f912e0adab8b0ee21f49f09438fa21 575 Gene3D G3DSA:1.10.3720.10 248 573 3.0E-25 T 29-03-2018 CB4_RS12915 99f912e0adab8b0ee21f49f09438fa21 575 Gene3D G3DSA:1.10.3720.10 15 247 1.4E-13 T 29-03-2018 CB4_RS12915 99f912e0adab8b0ee21f49f09438fa21 575 SUPERFAMILY SSF161098 370 560 8.63E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS12915 99f912e0adab8b0ee21f49f09438fa21 575 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 389 571 2.3E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS12915 99f912e0adab8b0ee21f49f09438fa21 575 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 252 5.0E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS12915 99f912e0adab8b0ee21f49f09438fa21 575 SUPERFAMILY SSF161098 58 257 2.22E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS03285 580f2947137b5898aeb29d9c3e0b4554 490 SUPERFAMILY SSF56954 171 236 3.14E-5 T 29-03-2018 CB4_RS03285 580f2947137b5898aeb29d9c3e0b4554 490 SUPERFAMILY SSF111369 52 161 5.75E-10 T 29-03-2018 CB4_RS03285 580f2947137b5898aeb29d9c3e0b4554 490 Gene3D G3DSA:1.20.1600.10 131 230 1.7E-12 T 29-03-2018 CB4_RS03285 580f2947137b5898aeb29d9c3e0b4554 490 Gene3D G3DSA:1.20.1600.10 231 489 4.0E-11 T 29-03-2018 CB4_RS03285 580f2947137b5898aeb29d9c3e0b4554 490 Pfam PF02321 Outer membrane efflux protein 155 237 1.2E-5 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CB4_RS03285 580f2947137b5898aeb29d9c3e0b4554 490 Pfam PF13437 HlyD family secretion protein 304 404 4.4E-12 T 29-03-2018 CB4_RS03285 580f2947137b5898aeb29d9c3e0b4554 490 Gene3D G3DSA:2.40.50.100 60 130 1.5E-13 T 29-03-2018 CB4_RS03285 580f2947137b5898aeb29d9c3e0b4554 490 Pfam PF13533 Biotin-lipoyl like 61 108 2.4E-9 T 29-03-2018 CB4_RS03285 580f2947137b5898aeb29d9c3e0b4554 490 SUPERFAMILY SSF111369 248 405 2.22E-9 T 29-03-2018 CB4_RS03285 580f2947137b5898aeb29d9c3e0b4554 490 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 233 488 2.4E-37 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 Pfam PF00571 CBS domain 226 275 3.0E-9 T 29-03-2018 IPR000644 CBS domain CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 Pfam PF00571 CBS domain 162 216 6.3E-9 T 29-03-2018 IPR000644 CBS domain CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 Pfam PF00027 Cyclic nucleotide-binding domain 33 119 4.2E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 Gene3D G3DSA:3.30.460.10 326 423 0.0013 T 29-03-2018 CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 490 628 1.9E-31 T 29-03-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 Gene3D G3DSA:2.60.120.10 1 147 3.5E-26 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 SUPERFAMILY SSF81301 309 411 4.9E-5 T 29-03-2018 CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 SUPERFAMILY SSF51206 7 141 9.3E-27 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 SMART SM00116 233 280 4.5E-6 T 29-03-2018 IPR000644 CBS domain CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 SMART SM00116 169 216 1.3E-6 T 29-03-2018 IPR000644 CBS domain CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 SMART SM00100 14 132 6.0E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 SUPERFAMILY SSF54631 161 278 8.72E-28 T 29-03-2018 CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 Gene3D G3DSA:3.10.580.10 154 325 2.2E-26 T 29-03-2018 CB4_RS17195 f3a2317b9bac886e38038a5f27cf058f 635 Pfam PF03445 Putative nucleotidyltransferase DUF294 305 448 2.3E-47 T 29-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 CB4_RS17665 5bba28d786b15d56e40f1e23036b6a86 169 SUPERFAMILY SSF52242 49 136 4.32E-5 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CB4_RS17665 5bba28d786b15d56e40f1e23036b6a86 169 Gene3D G3DSA:3.40.50.280 48 164 2.4E-4 T 29-03-2018 CB4_RS16265 806d0f416b195b81d4da01b4d2991c05 550 SUPERFAMILY SSF53850 36 542 3.8E-119 T 29-03-2018 CB4_RS16265 806d0f416b195b81d4da01b4d2991c05 550 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 472 4.0E-77 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CB4_RS16265 806d0f416b195b81d4da01b4d2991c05 550 Gene3D G3DSA:3.10.105.10 318 522 5.5E-49 T 29-03-2018 CB4_RS16265 806d0f416b195b81d4da01b4d2991c05 550 Gene3D G3DSA:3.40.190.10 182 317 5.7E-33 T 29-03-2018 CB4_RS16265 806d0f416b195b81d4da01b4d2991c05 550 PIRSF PIRSF002741 2 549 3.9E-106 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CB4_RS16265 806d0f416b195b81d4da01b4d2991c05 550 Gene3D G3DSA:3.90.76.10 64 181 2.7E-31 T 29-03-2018 CB4_RS05270 a3d314b3d745707274e216fd8533d47f 397 Gene3D G3DSA:3.50.50.60 4 141 2.0E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05270 a3d314b3d745707274e216fd8533d47f 397 SUPERFAMILY SSF51905 152 332 1.08E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05270 a3d314b3d745707274e216fd8533d47f 397 SUPERFAMILY SSF51905 4 208 4.76E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05270 a3d314b3d745707274e216fd8533d47f 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 8.7E-8 T 29-03-2018 CB4_RS05270 a3d314b3d745707274e216fd8533d47f 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.7E-8 T 29-03-2018 CB4_RS05270 a3d314b3d745707274e216fd8533d47f 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 8.7E-8 T 29-03-2018 CB4_RS05270 a3d314b3d745707274e216fd8533d47f 397 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 320 1.2E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05270 a3d314b3d745707274e216fd8533d47f 397 Gene3D G3DSA:3.50.50.60 146 353 6.3E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16445 1d6d9184d03273b1974b44c64f8378b0 342 SUPERFAMILY SSF55785 5 109 9.33E-7 T 29-03-2018 IPR000014 PAS domain CB4_RS16445 1d6d9184d03273b1974b44c64f8378b0 342 Gene3D G3DSA:3.30.565.10 197 339 3.4E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16445 1d6d9184d03273b1974b44c64f8378b0 342 Pfam PF07730 Histidine kinase 135 199 1.2E-14 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CB4_RS16445 1d6d9184d03273b1974b44c64f8378b0 342 PIRSF PIRSF037432 1 332 1.7E-48 T 29-03-2018 IPR017203 Signal transduction histidine kinase, NreB GO:0000155|GO:0004673|GO:0005506|GO:0005524|GO:0005737|GO:0018106 CB4_RS16445 1d6d9184d03273b1974b44c64f8378b0 342 Gene3D G3DSA:3.30.450.20 3 143 5.6E-10 T 29-03-2018 CB4_RS16445 1d6d9184d03273b1974b44c64f8378b0 342 Pfam PF13188 PAS domain 5 37 4.3E-4 T 29-03-2018 IPR000014 PAS domain CB4_RS16445 1d6d9184d03273b1974b44c64f8378b0 342 SMART SM00387 238 334 1.5E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16445 1d6d9184d03273b1974b44c64f8378b0 342 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 242 332 8.0E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16445 1d6d9184d03273b1974b44c64f8378b0 342 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 117 3.3E-6 T 29-03-2018 IPR000014 PAS domain CB4_RS16445 1d6d9184d03273b1974b44c64f8378b0 342 SUPERFAMILY SSF55874 204 332 1.38E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12400 85183e242713707593a48575b30189a3 229 Pfam PF02080 TrkA-C domain 151 216 1.4E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CB4_RS12400 85183e242713707593a48575b30189a3 229 SUPERFAMILY SSF116726 133 216 2.09E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CB4_RS12400 85183e242713707593a48575b30189a3 229 Gene3D G3DSA:3.30.70.1450 135 220 6.0E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CB4_RS20215 703461144ab98976698d1b6ad603b1c9 183 Gene3D G3DSA:1.10.260.40 1 77 1.7E-18 T 29-03-2018 CB4_RS20215 703461144ab98976698d1b6ad603b1c9 183 Pfam PF07883 Cupin domain 112 171 1.4E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CB4_RS20215 703461144ab98976698d1b6ad603b1c9 183 SUPERFAMILY SSF51182 54 176 5.3E-26 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS20215 703461144ab98976698d1b6ad603b1c9 183 Gene3D G3DSA:2.60.120.10 78 183 1.8E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS20215 703461144ab98976698d1b6ad603b1c9 183 SUPERFAMILY SSF47413 1 65 2.67E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS20215 703461144ab98976698d1b6ad603b1c9 183 SMART SM00530 6 61 1.5E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS20215 703461144ab98976698d1b6ad603b1c9 183 Pfam PF01381 Helix-turn-helix 7 61 1.2E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS02025 6a562217bc86ed9cd72e04b9dbd7b039 147 SUPERFAMILY SSF55653 56 147 1.31E-27 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CB4_RS02025 6a562217bc86ed9cd72e04b9dbd7b039 147 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02025 6a562217bc86ed9cd72e04b9dbd7b039 147 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 25.72 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS02025 6a562217bc86ed9cd72e04b9dbd7b039 147 Gene3D G3DSA:3.10.430.100 63 146 1.3E-29 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CB4_RS02025 6a562217bc86ed9cd72e04b9dbd7b039 147 SUPERFAMILY SSF55658 1 57 1.73E-18 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CB4_RS02025 6a562217bc86ed9cd72e04b9dbd7b039 147 Gene3D G3DSA:3.40.5.10 1 49 3.7E-23 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02025 6a562217bc86ed9cd72e04b9dbd7b039 147 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 8.0E-48 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS02025 6a562217bc86ed9cd72e04b9dbd7b039 147 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 1.2E-28 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CB4_RS02025 6a562217bc86ed9cd72e04b9dbd7b039 147 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 2.0E-23 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05005 930641ca83f127fe9405e5447a825f76 134 Pfam PF13411 MerR HTH family regulatory protein 2 62 2.1E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS05005 930641ca83f127fe9405e5447a825f76 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 9.5E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS05005 930641ca83f127fe9405e5447a825f76 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 9.5E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS05005 930641ca83f127fe9405e5447a825f76 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 9.5E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS05005 930641ca83f127fe9405e5447a825f76 134 Gene3D G3DSA:1.10.1660.10 1 56 3.6E-22 T 29-03-2018 CB4_RS05005 930641ca83f127fe9405e5447a825f76 134 SMART SM00422 2 70 1.6E-23 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS05005 930641ca83f127fe9405e5447a825f76 134 SUPERFAMILY SSF46955 2 122 1.47E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS05005 930641ca83f127fe9405e5447a825f76 134 Gene3D G3DSA:1.10.1660.10 57 133 1.0E-10 T 29-03-2018 CB4_RS04200 8ae526975012ae0b715ec77c10613393 244 Pfam PF02754 Cysteine-rich domain 3 83 5.1E-15 T 29-03-2018 IPR004017 Cysteine-rich domain CB4_RS04200 8ae526975012ae0b715ec77c10613393 244 Pfam PF02754 Cysteine-rich domain 132 216 5.4E-14 T 29-03-2018 IPR004017 Cysteine-rich domain CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 SUPERFAMILY SSF53613 4 300 1.71E-82 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 40 64 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 6 298 1.1E-103 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 Hamap MF_01987 Ribokinase [rbsK]. 4 299 25.859 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 Pfam PF00294 pfkB family carbohydrate kinase 5 292 3.3E-67 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 PRINTS PR00990 Ribokinase signature 8 29 5.5E-32 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 PRINTS PR00990 Ribokinase signature 35 54 5.5E-32 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 PRINTS PR00990 Ribokinase signature 106 119 5.5E-32 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 PRINTS PR00990 Ribokinase signature 174 189 5.5E-32 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 PRINTS PR00990 Ribokinase signature 214 225 5.5E-32 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 Gene3D G3DSA:3.40.1190.20 2 305 2.6E-83 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS18175 0ef9e17f3148678df1fb0ca987e0fe0a 305 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 244 257 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CB4_RS06760 62a03ec4c8922e81ceebcf1c4eabc935 147 SUPERFAMILY SSF46565 1 71 2.75E-28 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06760 62a03ec4c8922e81ceebcf1c4eabc935 147 Pfam PF00226 DnaJ domain 3 65 1.5E-25 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06760 62a03ec4c8922e81ceebcf1c4eabc935 147 SMART SM00271 2 60 2.9E-28 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06760 62a03ec4c8922e81ceebcf1c4eabc935 147 PRINTS PR00625 DnaJ domain signature 40 60 3.7E-19 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06760 62a03ec4c8922e81ceebcf1c4eabc935 147 PRINTS PR00625 DnaJ domain signature 5 23 3.7E-19 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06760 62a03ec4c8922e81ceebcf1c4eabc935 147 PRINTS PR00625 DnaJ domain signature 23 38 3.7E-19 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06760 62a03ec4c8922e81ceebcf1c4eabc935 147 Gene3D G3DSA:1.10.287.110 1 147 6.8E-29 T 29-03-2018 IPR001623 DnaJ domain CB4_RS11105 17def46ed84a173716e1cfb3fec0e7b6 377 Gene3D G3DSA:3.60.15.10 120 367 6.8E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS11105 17def46ed84a173716e1cfb3fec0e7b6 377 Pfam PF00753 Metallo-beta-lactamase superfamily 129 294 3.7E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS11105 17def46ed84a173716e1cfb3fec0e7b6 377 SUPERFAMILY SSF52821 3 109 1.31E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS11105 17def46ed84a173716e1cfb3fec0e7b6 377 Gene3D G3DSA:3.40.250.10 1 119 2.2E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS11105 17def46ed84a173716e1cfb3fec0e7b6 377 Pfam PF00581 Rhodanese-like domain 7 104 3.7E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS11105 17def46ed84a173716e1cfb3fec0e7b6 377 SUPERFAMILY SSF56281 118 332 3.01E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS11105 17def46ed84a173716e1cfb3fec0e7b6 377 SMART SM00450 7 109 2.0E-12 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS11105 17def46ed84a173716e1cfb3fec0e7b6 377 SMART SM00849 129 294 2.0E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS08430 491c23c006bea5d9b0904c99d8592ecc 659 Gene3D G3DSA:3.30.457.10 241 306 7.3E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS08430 491c23c006bea5d9b0904c99d8592ecc 659 Gene3D G3DSA:3.30.457.10 307 377 1.7E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS08430 491c23c006bea5d9b0904c99d8592ecc 659 Pfam PF01943 Polysaccharide biosynthesis protein 6 305 8.3E-31 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CB4_RS08430 491c23c006bea5d9b0904c99d8592ecc 659 Pfam PF07833 Copper amine oxidase N-terminal domain 298 376 2.4E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS08430 491c23c006bea5d9b0904c99d8592ecc 659 Pfam PF07833 Copper amine oxidase N-terminal domain 264 324 3.8E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS08430 491c23c006bea5d9b0904c99d8592ecc 659 SUPERFAMILY SSF55383 254 322 3.01E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS08430 491c23c006bea5d9b0904c99d8592ecc 659 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 475 620 2.0E-22 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CB4_RS15315 dc529d623191e741585827c8aa614cb3 767 Gene3D G3DSA:3.40.50.920 271 399 8.6E-23 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS15315 dc529d623191e741585827c8aa614cb3 767 Gene3D G3DSA:3.40.50.970 18 270 5.0E-39 T 29-03-2018 CB4_RS15315 dc529d623191e741585827c8aa614cb3 767 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 33 258 6.9E-54 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CB4_RS15315 dc529d623191e741585827c8aa614cb3 767 Gene3D G3DSA:3.40.50.970 454 548 4.6E-19 T 29-03-2018 CB4_RS15315 dc529d623191e741585827c8aa614cb3 767 Gene3D G3DSA:3.40.50.970 549 765 3.6E-25 T 29-03-2018 CB4_RS15315 dc529d623191e741585827c8aa614cb3 767 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 281 385 2.6E-19 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CB4_RS15315 dc529d623191e741585827c8aa614cb3 767 SUPERFAMILY SSF52922 273 396 2.57E-26 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS15315 dc529d623191e741585827c8aa614cb3 767 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 499 660 3.5E-10 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CB4_RS15315 dc529d623191e741585827c8aa614cb3 767 SUPERFAMILY SSF52518 20 270 3.39E-55 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS15315 dc529d623191e741585827c8aa614cb3 767 SUPERFAMILY SSF52518 401 766 1.57E-57 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS17710 17b362102227e71142846d7568c2c6bf 670 Gene3D G3DSA:3.40.50.300 1 288 7.5E-23 T 29-03-2018 CB4_RS17710 17b362102227e71142846d7568c2c6bf 670 Pfam PF02421 Ferrous iron transport protein B 2 152 1.1E-59 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CB4_RS17710 17b362102227e71142846d7568c2c6bf 670 Pfam PF07670 Nucleoside recognition 514 638 7.5E-34 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CB4_RS17710 17b362102227e71142846d7568c2c6bf 670 Pfam PF07670 Nucleoside recognition 353 446 1.0E-14 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CB4_RS17710 17b362102227e71142846d7568c2c6bf 670 SUPERFAMILY SSF52540 1 165 4.5E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS17710 17b362102227e71142846d7568c2c6bf 670 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 635 4.2E-193 T 29-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CB4_RS17710 17b362102227e71142846d7568c2c6bf 670 Pfam PF07664 Ferrous iron transport protein B C terminus 457 509 6.4E-20 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CB4_RS01425 1c4cd28909cff6bade30dc7bfcb1e34c 827 SUPERFAMILY SSF81606 603 803 1.24E-20 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS01425 1c4cd28909cff6bade30dc7bfcb1e34c 827 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 45 802 4.7E-236 T 29-03-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS01425 1c4cd28909cff6bade30dc7bfcb1e34c 827 Gene3D G3DSA:3.60.40.10 584 807 1.7E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS01425 1c4cd28909cff6bade30dc7bfcb1e34c 827 SMART SM00331 590 802 1.2E-41 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS01425 1c4cd28909cff6bade30dc7bfcb1e34c 827 SMART SM00332 582 800 0.0011 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS01425 1c4cd28909cff6bade30dc7bfcb1e34c 827 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 617 803 1.7E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS10795 94e874b08e54c6abdc1475ca7bfa623b 370 Pfam PF01590 GAF domain 29 157 6.6E-14 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS10795 94e874b08e54c6abdc1475ca7bfa623b 370 SUPERFAMILY SSF55781 12 179 9.81E-36 T 29-03-2018 IPR029016 GAF domain-like CB4_RS10795 94e874b08e54c6abdc1475ca7bfa623b 370 Pfam PF01966 HD domain 196 318 2.2E-20 T 29-03-2018 IPR006674 HD domain CB4_RS10795 94e874b08e54c6abdc1475ca7bfa623b 370 Gene3D G3DSA:3.30.450.40 9 169 1.4E-31 T 29-03-2018 IPR029016 GAF domain-like CB4_RS10795 94e874b08e54c6abdc1475ca7bfa623b 370 SUPERFAMILY SSF109604 183 359 1.22E-40 T 29-03-2018 CB4_RS10795 94e874b08e54c6abdc1475ca7bfa623b 370 Gene3D G3DSA:1.10.3210.10 170 368 8.2E-50 T 29-03-2018 CB4_RS10795 94e874b08e54c6abdc1475ca7bfa623b 370 SMART SM00471 191 328 4.0E-10 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS10795 94e874b08e54c6abdc1475ca7bfa623b 370 SMART SM00065 24 174 5.9E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS00495 875372b4469ea6035835d0c6556009e9 433 Pfam PF01979 Amidohydrolase family 77 418 4.0E-22 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CB4_RS00495 875372b4469ea6035835d0c6556009e9 433 SUPERFAMILY SSF51556 80 379 3.13E-88 T 29-03-2018 IPR032466 Metal-dependent hydrolase CB4_RS00495 875372b4469ea6035835d0c6556009e9 433 Hamap MF_00372 Imidazolonepropionase [hutI]. 5 418 43.375 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00495 875372b4469ea6035835d0c6556009e9 433 Gene3D G3DSA:2.30.40.10 358 423 3.1E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS00495 875372b4469ea6035835d0c6556009e9 433 Gene3D G3DSA:3.20.20.140 96 357 9.2E-45 T 29-03-2018 CB4_RS00495 875372b4469ea6035835d0c6556009e9 433 TIGRFAM TIGR01224 hutI: imidazolonepropionase 36 417 5.2E-151 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00495 875372b4469ea6035835d0c6556009e9 433 SUPERFAMILY SSF51338 36 81 8.53E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS00495 875372b4469ea6035835d0c6556009e9 433 SUPERFAMILY SSF51338 378 425 8.53E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS00495 875372b4469ea6035835d0c6556009e9 433 Gene3D G3DSA:2.30.40.10 5 95 8.5E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS12895 89ef20f8de54ba17ef93621c5591688a 143 Gene3D G3DSA:3.40.630.30 2 143 9.1E-17 T 29-03-2018 CB4_RS12895 89ef20f8de54ba17ef93621c5591688a 143 Pfam PF00583 Acetyltransferase (GNAT) family 27 130 9.5E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS12895 89ef20f8de54ba17ef93621c5591688a 143 SUPERFAMILY SSF55729 5 127 5.15E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS15685 b89484c589a43c54a11a2723857d0a14 376 Pfam PF00589 Phage integrase family 172 354 6.1E-28 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS15685 b89484c589a43c54a11a2723857d0a14 376 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 65 120 9.7E-16 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CB4_RS15685 b89484c589a43c54a11a2723857d0a14 376 Gene3D G3DSA:1.10.443.10 173 363 1.1E-42 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS15685 b89484c589a43c54a11a2723857d0a14 376 Gene3D G3DSA:1.10.150.130 59 172 3.2E-22 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CB4_RS15685 b89484c589a43c54a11a2723857d0a14 376 SUPERFAMILY SSF56349 64 363 2.59E-71 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS15685 b89484c589a43c54a11a2723857d0a14 376 Pfam PF14657 Arm DNA-binding domain 11 56 7.7E-17 T 29-03-2018 IPR028259 AP2-like integrase, N-terminal domain CB4_RS20290 1a869e8a8b26b5c6a0352f1f1e75347c 387 SUPERFAMILY SSF159774 92 380 9.81E-94 T 29-03-2018 IPR023158 YerB-like CB4_RS20290 1a869e8a8b26b5c6a0352f1f1e75347c 387 Gene3D G3DSA:3.50.90.10 79 387 2.6E-103 T 29-03-2018 IPR023158 YerB-like CB4_RS20290 1a869e8a8b26b5c6a0352f1f1e75347c 387 Pfam PF11258 Protein of unknown function (DUF3048) N-terminal domain 96 236 9.8E-48 T 29-03-2018 IPR021416 Protein of unknown function DUF3048, N-terminal CB4_RS20290 1a869e8a8b26b5c6a0352f1f1e75347c 387 Pfam PF17479 Protein of unknown function (DUF3048) C-terminal domain 262 371 4.1E-30 T 29-03-2018 IPR035328 Protein of unknown function DUF3048, C-terminal domain CB4_RS12405 c5be7586151b401102d7a6d97997eec1 385 SUPERFAMILY SSF56112 6 134 5.6E-6 T 29-03-2018 IPR011009 Protein kinase-like domain CB4_RS12405 c5be7586151b401102d7a6d97997eec1 385 Pfam PF03793 PASTA domain 324 385 1.2E-13 T 29-03-2018 IPR005543 PASTA domain CB4_RS12405 c5be7586151b401102d7a6d97997eec1 385 SUPERFAMILY SSF54184 324 383 7.98E-5 T 29-03-2018 CB4_RS12405 c5be7586151b401102d7a6d97997eec1 385 SMART SM00740 320 385 2.2E-7 T 29-03-2018 IPR005543 PASTA domain CB4_RS03985 896ac860848203db170c11e0146f68dd 682 Pfam PF13426 PAS domain 249 344 4.2E-4 T 29-03-2018 IPR000014 PAS domain CB4_RS03985 896ac860848203db170c11e0146f68dd 682 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 455 470 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CB4_RS03985 896ac860848203db170c11e0146f68dd 682 Gene3D G3DSA:3.30.450.20 219 352 1.4E-8 T 29-03-2018 CB4_RS03985 896ac860848203db170c11e0146f68dd 682 Gene3D G3DSA:3.40.50.300 361 540 2.1E-29 T 29-03-2018 CB4_RS03985 896ac860848203db170c11e0146f68dd 682 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 119 174 1.2E-5 T 29-03-2018 IPR000014 PAS domain CB4_RS03985 896ac860848203db170c11e0146f68dd 682 Gene3D G3DSA:1.10.10.60 637 677 1.6E-9 T 29-03-2018 CB4_RS03985 896ac860848203db170c11e0146f68dd 682 SMART SM00382 388 538 4.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS03985 896ac860848203db170c11e0146f68dd 682 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 392 405 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CB4_RS03985 896ac860848203db170c11e0146f68dd 682 SUPERFAMILY SSF55785 118 212 2.66E-9 T 29-03-2018 IPR000014 PAS domain CB4_RS03985 896ac860848203db170c11e0146f68dd 682 SUPERFAMILY SSF52540 368 606 7.46E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03985 896ac860848203db170c11e0146f68dd 682 Pfam PF13188 PAS domain 120 160 2.8E-5 T 29-03-2018 IPR000014 PAS domain CB4_RS03985 896ac860848203db170c11e0146f68dd 682 Gene3D G3DSA:3.30.450.20 117 216 2.8E-10 T 29-03-2018 CB4_RS03985 896ac860848203db170c11e0146f68dd 682 SUPERFAMILY SSF55785 231 343 3.66E-5 T 29-03-2018 IPR000014 PAS domain CB4_RS03985 896ac860848203db170c11e0146f68dd 682 Pfam PF02954 Bacterial regulatory protein, Fis family 637 676 1.4E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS03985 896ac860848203db170c11e0146f68dd 682 Pfam PF00158 Sigma-54 interaction domain 368 535 4.7E-71 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS03985 896ac860848203db170c11e0146f68dd 682 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 581 590 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CB4_RS03985 896ac860848203db170c11e0146f68dd 682 SMART SM00091 236 306 270.0 T 29-03-2018 IPR000014 PAS domain CB4_RS03985 896ac860848203db170c11e0146f68dd 682 SMART SM00091 119 186 1.9E-4 T 29-03-2018 IPR000014 PAS domain CB4_RS03985 896ac860848203db170c11e0146f68dd 682 Gene3D G3DSA:1.10.8.60 541 636 1.6E-20 T 29-03-2018 CB4_RS03985 896ac860848203db170c11e0146f68dd 682 SUPERFAMILY SSF46689 629 676 6.09E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 Pfam PF00842 Alanine racemase, C-terminal domain 248 375 5.2E-49 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 PRINTS PR00992 Alanine racemase signature 69 87 1.7E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 PRINTS PR00992 Alanine racemase signature 33 49 1.7E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 PRINTS PR00992 Alanine racemase signature 281 296 1.7E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 PRINTS PR00992 Alanine racemase signature 164 175 1.7E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 PRINTS PR00992 Alanine racemase signature 264 279 1.7E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 PRINTS PR00992 Alanine racemase signature 302 319 1.7E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 PRINTS PR00992 Alanine racemase signature 130 142 1.7E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 PRINTS PR00992 Alanine racemase signature 207 234 1.7E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 PRINTS PR00992 Alanine racemase signature 358 371 1.7E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 TIGRFAM TIGR00492 alr: alanine racemase 8 377 4.6E-120 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 Gene3D G3DSA:3.20.20.10 5 232 3.1E-49 T 29-03-2018 IPR029066 PLP-binding barrel CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 Gene3D G3DSA:2.40.37.10 233 385 1.6E-65 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 SMART SM01005 248 376 1.9E-75 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 SUPERFAMILY SSF50621 242 379 3.07E-54 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 Pfam PF01168 Alanine racemase, N-terminal domain 14 234 1.3E-65 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 SUPERFAMILY SSF51419 14 249 3.2E-62 T 29-03-2018 IPR029066 PLP-binding barrel CB4_RS20540 5d4281ee7d44ae7ebc617147e0b27da0 395 Hamap MF_01201 Alanine racemase. 7 376 34.778 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 223 3.7E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 4 228 1.9E-110 T 29-03-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 SUPERFAMILY SSF88659 137 225 6.54E-20 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 Gene3D G3DSA:1.10.601.10 18 121 4.7E-28 T 29-03-2018 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 Pfam PF04545 Sigma-70, region 4 175 224 1.0E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 SUPERFAMILY SSF88946 7 122 1.44E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 Gene3D G3DSA:1.10.1270.10 143 236 9.6E-20 T 29-03-2018 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 197 223 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 PRINTS PR00046 Major sigma-70 factor signature 78 91 1.4E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 PRINTS PR00046 Major sigma-70 factor signature 176 188 1.4E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 PRINTS PR00046 Major sigma-70 factor signature 197 212 1.4E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 PRINTS PR00046 Major sigma-70 factor signature 212 223 1.4E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 Pfam PF04542 Sigma-70 region 2 54 123 2.3E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06365 dde5c72358a9a60d88935ed155f49930 237 PIRSF PIRSF000770 1 237 7.5E-86 T 29-03-2018 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 Gene3D G3DSA:3.40.50.2300 423 552 1.0E-34 T 29-03-2018 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 SUPERFAMILY SSF52172 120 254 1.21E-37 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 Pfam PF01627 Hpt domain 34 66 4.0E-5 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 Gene3D G3DSA:3.30.70.270 250 422 3.0E-51 T 29-03-2018 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 SMART SM00267 241 415 3.1E-48 T 29-03-2018 IPR000160 GGDEF domain CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 Gene3D G3DSA:3.40.50.2300 132 249 1.0E-31 T 29-03-2018 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 SUPERFAMILY SSF55073 257 415 1.8E-48 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 Pfam PF00072 Response regulator receiver domain 127 238 1.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 Pfam PF00072 Response regulator receiver domain 431 543 4.0E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 Pfam PF00990 Diguanylate cyclase, GGDEF domain 253 411 2.9E-45 T 29-03-2018 IPR000160 GGDEF domain CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 Gene3D G3DSA:1.20.120.160 3 131 2.6E-8 T 29-03-2018 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 SMART SM00448 125 238 2.1E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 SMART SM00448 429 542 2.8E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 251 414 1.4E-47 T 29-03-2018 IPR000160 GGDEF domain CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 SUPERFAMILY SSF47226 8 66 3.93E-7 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CB4_RS16995 12422ea68bef9c0a9238e6e7a99380bd 552 SUPERFAMILY SSF52172 427 546 7.83E-35 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 Gene3D G3DSA:3.40.50.10380 4 158 4.7E-42 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 SUPERFAMILY SSF51735 161 403 3.56E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 SMART SM00919 161 385 9.9E-136 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 Pfam PF03949 Malic enzyme, NAD binding domain 163 385 8.1E-25 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 Gene3D G3DSA:3.40.50.720 159 407 2.7E-88 T 29-03-2018 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 SUPERFAMILY SSF53223 7 159 4.82E-57 T 29-03-2018 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 Pfam PF00390 Malic enzyme, N-terminal domain 18 149 7.0E-30 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 PRINTS PR00072 Malic enzyme signature 78 100 5.5E-8 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 PRINTS PR00072 Malic enzyme signature 157 173 5.5E-8 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 PRINTS PR00072 Malic enzyme signature 277 293 5.5E-8 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 SMART SM01274 16 149 1.7E-87 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 PIRSF PIRSF000106 42 408 1.3E-89 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CB4_RS18435 8303b928f69b643134220b893ecf32e8 409 ProSitePatterns PS00331 Malic enzymes signature. 157 173 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CB4_RS05675 ab1d3f171a535582abfa5f8a3c39fb23 261 Gene3D G3DSA:3.40.50.10090 163 260 1.2E-25 T 29-03-2018 CB4_RS05675 ab1d3f171a535582abfa5f8a3c39fb23 261 Pfam PF02602 Uroporphyrinogen-III synthase HemD 23 250 4.7E-59 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05675 ab1d3f171a535582abfa5f8a3c39fb23 261 SUPERFAMILY SSF69618 9 257 3.92E-69 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05675 ab1d3f171a535582abfa5f8a3c39fb23 261 Gene3D G3DSA:3.40.50.10090 41 162 6.3E-31 T 29-03-2018 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 SMART SM00532 5 445 5.1E-274 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 405 431 5.9E-11 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Gene3D G3DSA:3.30.1490.70 237 319 1.2E-28 T 29-03-2018 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Pfam PF14520 Helix-hairpin-helix domain 445 498 1.3E-8 T 29-03-2018 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 SUPERFAMILY SSF47781 402 581 1.67E-64 T 29-03-2018 IPR010994 RuvA domain 2-like CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Gene3D G3DSA:3.40.50.10190 569 669 1.4E-23 T 29-03-2018 IPR001357 BRCT domain CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 320 396 5.9E-33 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 7 316 1.9E-128 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 PIRSF PIRSF001604 1 669 1.8E-260 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Gene3D G3DSA:1.10.150.20 503 568 3.0E-24 T 29-03-2018 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Gene3D G3DSA:3.30.470.30 121 236 2.1E-48 T 29-03-2018 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Gene3D G3DSA:1.10.150.20 429 502 2.3E-30 T 29-03-2018 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 117 146 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 592 664 8.5E-16 T 29-03-2018 IPR001357 BRCT domain CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Gene3D G3DSA:2.40.50.140 320 388 1.1E-31 T 29-03-2018 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Pfam PF12826 Helix-hairpin-helix motif 507 569 1.4E-22 T 29-03-2018 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 SUPERFAMILY SSF50249 315 399 1.11E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 SUPERFAMILY SSF52113 593 668 4.3E-20 T 29-03-2018 IPR001357 BRCT domain CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 329 344 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 SUPERFAMILY SSF56091 2 314 1.03E-120 T 29-03-2018 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Hamap MF_01588 DNA ligase [ligA]. 4 667 53.308 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 SMART SM00292 593 669 8.7E-11 T 29-03-2018 IPR001357 BRCT domain CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 Gene3D G3DSA:1.10.287.610 1 69 2.0E-25 T 29-03-2018 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 663 5.8E-268 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 SMART SM00278 477 496 5.8 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 SMART SM00278 541 560 82.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CB4_RS20270 1e783a1640469a83438a27de345f17aa 669 SMART SM00278 443 462 2.1 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CB4_RS14590 4f06340f1736babebc246369aa98a95d 283 Pfam PF03466 LysR substrate binding domain 90 282 2.7E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CB4_RS14590 4f06340f1736babebc246369aa98a95d 283 Gene3D G3DSA:1.10.10.10 1 84 2.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14590 4f06340f1736babebc246369aa98a95d 283 SUPERFAMILY SSF46785 1 109 2.84E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14590 4f06340f1736babebc246369aa98a95d 283 Gene3D G3DSA:3.40.190.10 173 260 3.7E-21 T 29-03-2018 CB4_RS14590 4f06340f1736babebc246369aa98a95d 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS14590 4f06340f1736babebc246369aa98a95d 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS14590 4f06340f1736babebc246369aa98a95d 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS14590 4f06340f1736babebc246369aa98a95d 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 1.9E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS14590 4f06340f1736babebc246369aa98a95d 283 Gene3D G3DSA:3.40.190.10 87 172 1.6E-12 T 29-03-2018 CB4_RS14590 4f06340f1736babebc246369aa98a95d 283 SUPERFAMILY SSF53850 90 276 5.97E-30 T 29-03-2018 CB4_RS00780 30d9629a5f2a5851581ca235933da5e9 657 Pfam PF07730 Histidine kinase 457 517 1.0E-13 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CB4_RS00780 30d9629a5f2a5851581ca235933da5e9 657 Gene3D G3DSA:3.30.565.10 530 656 8.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00780 30d9629a5f2a5851581ca235933da5e9 657 SUPERFAMILY SSF49785 48 191 5.38E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS00780 30d9629a5f2a5851581ca235933da5e9 657 Pfam PF07695 7TM diverse intracellular signalling 208 397 4.6E-22 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 CB4_RS00780 30d9629a5f2a5851581ca235933da5e9 657 Gene3D G3DSA:2.60.120.260 43 209 1.7E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS00780 30d9629a5f2a5851581ca235933da5e9 657 SUPERFAMILY SSF55874 535 647 7.92E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00780 30d9629a5f2a5851581ca235933da5e9 657 Gene3D G3DSA:1.10.287.370 407 529 1.4E-4 T 29-03-2018 CB4_RS00780 30d9629a5f2a5851581ca235933da5e9 657 SMART SM00387 560 650 0.008 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS20195 7aa001bf256eda14a9bcab59776af853 477 Pfam PF02637 GatB domain 327 474 8.5E-58 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CB4_RS20195 7aa001bf256eda14a9bcab59776af853 477 Pfam PF02934 GatB/GatE catalytic domain 5 288 1.1E-114 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CB4_RS20195 7aa001bf256eda14a9bcab59776af853 477 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 474 5.9E-186 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CB4_RS20195 7aa001bf256eda14a9bcab59776af853 477 SUPERFAMILY SSF89095 296 402 1.36E-37 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CB4_RS20195 7aa001bf256eda14a9bcab59776af853 477 SUPERFAMILY SSF55931 4 295 3.66E-123 T 29-03-2018 CB4_RS20195 7aa001bf256eda14a9bcab59776af853 477 Gene3D G3DSA:1.10.10.410 414 475 1.1E-24 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CB4_RS20195 7aa001bf256eda14a9bcab59776af853 477 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 143 157 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CB4_RS20195 7aa001bf256eda14a9bcab59776af853 477 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 475 40.356 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CB4_RS20195 7aa001bf256eda14a9bcab59776af853 477 SMART SM00845 327 474 8.7E-83 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CB4_RS13510 8a668a11702338eca9f244a03c6af648 229 SUPERFAMILY SSF46894 126 227 1.81E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS13510 8a668a11702338eca9f244a03c6af648 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 1.1E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS13510 8a668a11702338eca9f244a03c6af648 229 Pfam PF00072 Response regulator receiver domain 6 115 5.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13510 8a668a11702338eca9f244a03c6af648 229 Gene3D G3DSA:1.10.10.10 124 228 9.5E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13510 8a668a11702338eca9f244a03c6af648 229 SMART SM00448 4 114 1.4E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13510 8a668a11702338eca9f244a03c6af648 229 SMART SM00862 151 226 1.7E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS13510 8a668a11702338eca9f244a03c6af648 229 Gene3D G3DSA:3.40.50.2300 1 123 2.9E-37 T 29-03-2018 CB4_RS13510 8a668a11702338eca9f244a03c6af648 229 SUPERFAMILY SSF52172 2 125 9.68E-42 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 Gene3D G3DSA:1.10.510.10 86 495 4.9E-58 T 29-03-2018 CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 SUPERFAMILY SSF54184 529 589 6.8E-6 T 29-03-2018 CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 SMART SM00220 17 277 5.8E-71 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 Pfam PF00069 Protein kinase domain 17 270 6.6E-56 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 SMART SM00740 458 524 1.1E-11 T 29-03-2018 IPR005543 PASTA domain CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 SMART SM00740 391 457 8.9E-13 T 29-03-2018 IPR005543 PASTA domain CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 SMART SM00740 526 590 5.5E-10 T 29-03-2018 IPR005543 PASTA domain CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 Gene3D G3DSA:3.30.200.20 5 85 2.0E-23 T 29-03-2018 CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 Pfam PF03793 PASTA domain 465 524 1.2E-11 T 29-03-2018 IPR005543 PASTA domain CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 Pfam PF03793 PASTA domain 530 589 1.2E-11 T 29-03-2018 IPR005543 PASTA domain CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 Pfam PF03793 PASTA domain 395 457 5.0E-12 T 29-03-2018 IPR005543 PASTA domain CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 46 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CB4_RS08510 406c773fd987363c5e2e5e04ff96203b 674 SUPERFAMILY SSF56112 13 278 2.02E-85 T 29-03-2018 IPR011009 Protein kinase-like domain CB4_RS17890 4ea987273d23236ec84691d8c3ff4768 508 Pfam PF00270 DEAD/DEAH box helicase 26 192 1.9E-51 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS17890 4ea987273d23236ec84691d8c3ff4768 508 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 2 505 43.589 T 29-03-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 CB4_RS17890 4ea987273d23236ec84691d8c3ff4768 508 Pfam PF00271 Helicase conserved C-terminal domain 227 335 1.5E-29 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS17890 4ea987273d23236ec84691d8c3ff4768 508 SUPERFAMILY SSF52540 72 356 5.29E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS17890 4ea987273d23236ec84691d8c3ff4768 508 Gene3D G3DSA:3.40.50.300 6 218 5.6E-61 T 29-03-2018 CB4_RS17890 4ea987273d23236ec84691d8c3ff4768 508 SMART SM00490 254 335 4.2E-34 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS17890 4ea987273d23236ec84691d8c3ff4768 508 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CB4_RS17890 4ea987273d23236ec84691d8c3ff4768 508 Gene3D G3DSA:3.40.50.300 219 502 3.3E-46 T 29-03-2018 CB4_RS17890 4ea987273d23236ec84691d8c3ff4768 508 SMART SM00487 21 218 2.5E-64 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS16045 094cfcb9672c70e778c1eaac2d871716 145 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CB4_RS16045 094cfcb9672c70e778c1eaac2d871716 145 SUPERFAMILY SSF50891 4 138 2.63E-49 T 29-03-2018 IPR029000 Cyclophilin-like domain CB4_RS16045 094cfcb9672c70e778c1eaac2d871716 145 Gene3D G3DSA:2.40.100.10 1 145 4.0E-52 T 29-03-2018 IPR029000 Cyclophilin-like domain CB4_RS16045 094cfcb9672c70e778c1eaac2d871716 145 PIRSF PIRSF001467 1 145 2.5E-40 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CB4_RS16045 094cfcb9672c70e778c1eaac2d871716 145 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 138 7.8E-43 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CB4_RS16045 094cfcb9672c70e778c1eaac2d871716 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 100 112 5.4E-26 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CB4_RS16045 094cfcb9672c70e778c1eaac2d871716 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 113 128 5.4E-26 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CB4_RS16045 094cfcb9672c70e778c1eaac2d871716 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 5.4E-26 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CB4_RS16045 094cfcb9672c70e778c1eaac2d871716 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 5.4E-26 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CB4_RS16045 094cfcb9672c70e778c1eaac2d871716 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 5.4E-26 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 45.285 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 1.1E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 1.1E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 1.1E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 1.1E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 1.1E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 Gene3D G3DSA:3.90.226.10 2 194 7.8E-48 T 29-03-2018 CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 29-03-2018 IPR018215 ClpP, Ser active site CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 2 191 3.1E-107 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 SUPERFAMILY SSF52096 10 193 7.07E-75 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 29-03-2018 IPR033135 ClpP, histidine active site CB4_RS03820 670f8feab310e60bb08b164feabc2178 201 Pfam PF00574 Clp protease 13 191 3.8E-89 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 Pfam PF00005 ABC transporter 336 469 9.3E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 Pfam PF00005 ABC transporter 20 187 1.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 Gene3D G3DSA:3.40.50.300 314 623 1.6E-54 T 29-03-2018 CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 Gene3D G3DSA:3.40.50.300 1 268 5.6E-58 T 29-03-2018 CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 SUPERFAMILY SSF52540 310 516 2.98E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 Pfam PF12848 ABC transporter 226 298 7.6E-14 T 29-03-2018 IPR032781 ABC-transporter extension domain CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 Pfam PF16326 ABC transporter C-terminal domain 559 624 4.9E-16 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 SUPERFAMILY SSF52540 4 240 2.67E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 SMART SM00382 343 524 4.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS12705 77ffe8df9c55d2478694f9adfc52ee47 637 SMART SM00382 28 232 1.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS06465 1eba6f156c50705570ed0fd36a5e8c8c 578 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 347 528 1.3E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS06465 1eba6f156c50705570ed0fd36a5e8c8c 578 Gene3D G3DSA:1.10.287.1060 249 335 0.01 T 29-03-2018 CB4_RS06465 1eba6f156c50705570ed0fd36a5e8c8c 578 SUPERFAMILY SSF58104 308 576 2.49E-78 T 29-03-2018 CB4_RS06465 1eba6f156c50705570ed0fd36a5e8c8c 578 SUPERFAMILY SSF58104 241 275 2.49E-78 T 29-03-2018 CB4_RS06465 1eba6f156c50705570ed0fd36a5e8c8c 578 Gene3D G3DSA:1.20.120.30 34 193 6.6E-15 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CB4_RS06465 1eba6f156c50705570ed0fd36a5e8c8c 578 SMART SM00283 302 577 2.2E-92 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS06465 1eba6f156c50705570ed0fd36a5e8c8c 578 SMART SM00304 221 273 1.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS06465 1eba6f156c50705570ed0fd36a5e8c8c 578 Gene3D G3DSA:1.10.287.950 336 578 9.1E-60 T 29-03-2018 CB4_RS06465 1eba6f156c50705570ed0fd36a5e8c8c 578 Pfam PF12729 Four helix bundle sensory module for signal transduction 14 193 2.1E-38 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS06465 1eba6f156c50705570ed0fd36a5e8c8c 578 Pfam PF00672 HAMP domain 223 268 8.6E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 PIRSF PIRSF001587 31 766 0.0 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 Gene3D G3DSA:3.30.1330.10 443 591 5.9E-50 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 Gene3D G3DSA:3.30.1330.10 46 222 4.8E-57 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 SUPERFAMILY SSF55326 41 224 9.12E-54 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 46 764 0.0 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 SUPERFAMILY SSF56042 596 765 7.03E-44 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 Pfam PF02769 AIR synthase related protein, C-terminal domain 600 735 3.4E-22 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 Pfam PF02769 AIR synthase related protein, C-terminal domain 230 382 6.0E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 SUPERFAMILY SSF56042 228 454 4.78E-60 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 Gene3D G3DSA:3.90.650.10 227 401 2.4E-30 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 Gene3D G3DSA:3.90.650.10 593 766 6.1E-40 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 Pfam PF00586 AIR synthase related protein, N-terminal domain 112 217 1.6E-25 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 Pfam PF00586 AIR synthase related protein, N-terminal domain 469 586 1.7E-24 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 SUPERFAMILY SSF55326 427 594 8.5E-58 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20370 b57f7e8782a4c3df689084cf243eb377 766 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 766 333.661 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 SUPERFAMILY SSF103190 57 181 1.05E-9 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 Gene3D G3DSA:1.10.287.950 329 408 7.3E-7 T 29-03-2018 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 SMART SM00283 382 657 3.9E-66 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 Gene3D G3DSA:3.30.450.20 158 280 4.5E-26 T 29-03-2018 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 Pfam PF02743 Cache domain 51 263 6.1E-28 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 Gene3D G3DSA:1.10.287.950 409 660 1.4E-54 T 29-03-2018 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 Gene3D G3DSA:3.30.450.20 52 157 3.6E-19 T 29-03-2018 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 Pfam PF00672 HAMP domain 302 349 5.0E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 SMART SM00304 301 353 3.3E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 SUPERFAMILY SSF58104 388 657 4.05E-69 T 29-03-2018 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 SUPERFAMILY SSF58104 321 355 4.05E-69 T 29-03-2018 CB4_RS01180 a213a38926e0ac8f0a4005d2a5c12b79 660 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 439 586 3.2E-39 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 418 8.4E-24 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 488 1.7E-176 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 Gene3D G3DSA:3.40.1190.10 97 336 6.9E-69 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 SUPERFAMILY SSF53244 332 490 9.03E-50 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 Gene3D G3DSA:3.90.190.20 337 493 1.0E-51 T 29-03-2018 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 488 37.124 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 SUPERFAMILY SSF63418 3 97 2.22E-28 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 104 127 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 Pfam PF08245 Mur ligase middle domain 106 312 1.2E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 Gene3D G3DSA:3.40.1390.10 2 96 1.4E-30 T 29-03-2018 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 Pfam PF01225 Mur ligase family, catalytic domain 22 94 1.9E-17 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CB4_RS08235 ae16a20157c3b8fa252f144ff3988c59 493 SUPERFAMILY SSF53623 97 331 2.49E-75 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Gene3D G3DSA:3.10.580.10 2 124 1.3E-17 T 29-03-2018 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 SMART SM00382 405 549 9.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 SUPERFAMILY SSF55785 128 197 2.09E-12 T 29-03-2018 IPR000014 PAS domain CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 472 487 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Gene3D G3DSA:1.10.10.60 628 694 3.9E-19 T 29-03-2018 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 SUPERFAMILY SSF52540 385 630 8.16E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Pfam PF00571 CBS domain 5 52 8.8E-5 T 29-03-2018 IPR000644 CBS domain CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Gene3D G3DSA:1.10.8.60 574 627 1.4E-20 T 29-03-2018 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Pfam PF02954 Bacterial regulatory protein, Fis family 652 691 4.7E-15 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 SUPERFAMILY SSF55785 228 341 9.99E-9 T 29-03-2018 IPR000014 PAS domain CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 674 694 5.2E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 657 674 5.2E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 409 422 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 131 238 6.2E-11 T 29-03-2018 IPR000014 PAS domain CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 SUPERFAMILY SSF46689 599 693 2.09E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Pfam PF00158 Sigma-54 interaction domain 385 551 2.8E-70 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Gene3D G3DSA:3.40.50.300 363 573 8.6E-30 T 29-03-2018 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 SMART SM00091 131 197 6.4E-11 T 29-03-2018 IPR000014 PAS domain CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 SMART SM00091 247 314 2.9E-4 T 29-03-2018 IPR000014 PAS domain CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Pfam PF00989 PAS fold 131 209 2.2E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Pfam PF00989 PAS fold 248 297 2.0E-5 T 29-03-2018 IPR013767 PAS fold GO:0006355 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 SUPERFAMILY SSF54631 3 124 9.18E-20 T 29-03-2018 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Gene3D G3DSA:3.30.450.20 125 236 1.2E-13 T 29-03-2018 CB4_RS09840 8267e1e3eb92b3780f4193d8edc3a97c 696 Gene3D G3DSA:3.30.450.20 237 354 1.4E-6 T 29-03-2018 CB4_RS01280 1864399970e9ad1718876f5ed4c3baa7 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 289 1.1E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS01280 1864399970e9ad1718876f5ed4c3baa7 292 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 28 291 2.7E-90 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CB4_RS01280 1864399970e9ad1718876f5ed4c3baa7 292 SUPERFAMILY SSF161098 35 284 1.07E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS01280 1864399970e9ad1718876f5ed4c3baa7 292 Gene3D G3DSA:1.10.3720.10 17 286 3.9E-36 T 29-03-2018 CB4_RS02855 71c97323d294ac347b116fe2a6dce373 405 Gene3D G3DSA:1.10.150.280 254 336 0.0016 T 29-03-2018 CB4_RS02855 71c97323d294ac347b116fe2a6dce373 405 Pfam PF01548 Transposase 5 160 6.8E-21 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CB4_RS02855 71c97323d294ac347b116fe2a6dce373 405 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 349 2.4E-23 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CB4_RS10375 71c97323d294ac347b116fe2a6dce373 405 Gene3D G3DSA:1.10.150.280 254 336 0.0016 T 29-03-2018 CB4_RS10375 71c97323d294ac347b116fe2a6dce373 405 Pfam PF01548 Transposase 5 160 6.8E-21 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CB4_RS10375 71c97323d294ac347b116fe2a6dce373 405 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 349 2.4E-23 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CB4_RS07325 71c97323d294ac347b116fe2a6dce373 405 Gene3D G3DSA:1.10.150.280 254 336 0.0016 T 29-03-2018 CB4_RS07325 71c97323d294ac347b116fe2a6dce373 405 Pfam PF01548 Transposase 5 160 6.8E-21 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CB4_RS07325 71c97323d294ac347b116fe2a6dce373 405 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 349 2.4E-23 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CB4_RS14705 71c97323d294ac347b116fe2a6dce373 405 Gene3D G3DSA:1.10.150.280 254 336 0.0016 T 29-03-2018 CB4_RS14705 71c97323d294ac347b116fe2a6dce373 405 Pfam PF01548 Transposase 5 160 6.8E-21 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CB4_RS14705 71c97323d294ac347b116fe2a6dce373 405 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 349 2.4E-23 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CB4_RS18285 71c97323d294ac347b116fe2a6dce373 405 Gene3D G3DSA:1.10.150.280 254 336 0.0016 T 29-03-2018 CB4_RS18285 71c97323d294ac347b116fe2a6dce373 405 Pfam PF01548 Transposase 5 160 6.8E-21 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CB4_RS18285 71c97323d294ac347b116fe2a6dce373 405 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 349 2.4E-23 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CB4_RS18255 71c97323d294ac347b116fe2a6dce373 405 Gene3D G3DSA:1.10.150.280 254 336 0.0016 T 29-03-2018 CB4_RS18255 71c97323d294ac347b116fe2a6dce373 405 Pfam PF01548 Transposase 5 160 6.8E-21 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CB4_RS18255 71c97323d294ac347b116fe2a6dce373 405 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 349 2.4E-23 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CB4_RS05190 71c97323d294ac347b116fe2a6dce373 405 Gene3D G3DSA:1.10.150.280 254 336 0.0016 T 29-03-2018 CB4_RS05190 71c97323d294ac347b116fe2a6dce373 405 Pfam PF01548 Transposase 5 160 6.8E-21 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CB4_RS05190 71c97323d294ac347b116fe2a6dce373 405 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 349 2.4E-23 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 SUPERFAMILY SSF89372 30 232 4.18E-9 T 29-03-2018 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Gene3D G3DSA:2.120.10.10 94 296 1.5E-7 T 29-03-2018 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Gene3D G3DSA:2.60.40.1080 642 728 9.5E-26 T 29-03-2018 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Gene3D G3DSA:2.60.40.1080 554 641 3.7E-26 T 29-03-2018 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Gene3D G3DSA:2.60.40.1080 376 463 1.7E-25 T 29-03-2018 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 SUPERFAMILY SSF49373 557 639 1.22E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 SMART SM00635 644 722 4.2E-21 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 SMART SM00635 379 457 2.0E-19 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 SMART SM00635 558 636 1.6E-21 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 SUPERFAMILY SSF49373 643 725 3.41E-20 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Pfam PF02368 Bacterial Ig-like domain (group 2) 559 637 1.7E-15 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Pfam PF02368 Bacterial Ig-like domain (group 2) 379 458 3.8E-15 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Pfam PF02368 Bacterial Ig-like domain (group 2) 645 723 2.6E-15 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Pfam PF00395 S-layer homology domain 985 1025 8.2E-16 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Pfam PF00395 S-layer homology domain 1103 1146 1.3E-14 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Pfam PF00395 S-layer homology domain 1045 1086 1.5E-13 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 SUPERFAMILY SSF49373 378 460 6.67E-20 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 Pfam PF12733 Cadherin-like beta sandwich domain 464 555 2.9E-15 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain CB4_RS04340 7b69449aa4dc899493aee36e1d5f918f 1157 SUPERFAMILY SSF89372 199 451 1.2E-12 T 29-03-2018 CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 113 419 7.8E-86 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 SMART SM00245 228 414 5.9E-47 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 Pfam PF13180 PDZ domain 158 232 3.6E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 Pfam PF03572 Peptidase family S41 253 411 4.6E-47 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 Gene3D G3DSA:3.30.750.44 76 161 6.2E-12 T 29-03-2018 CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 SUPERFAMILY SSF50156 144 239 4.66E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 SUPERFAMILY SSF52096 89 175 1.09E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 SUPERFAMILY SSF52096 247 418 1.09E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 Gene3D G3DSA:3.90.226.10 240 428 5.2E-56 T 29-03-2018 CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 SMART SM00228 157 228 4.9E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS03335 babfa825ea8e4e24efbbb6e3cf7d5b50 539 Gene3D G3DSA:2.30.42.10 162 239 8.6E-18 T 29-03-2018 CB4_RS05310 e1cbe875ce7633ff0dcbc69283919f31 165 Pfam PF10369 Small subunit of acetolactate synthase 86 158 3.7E-29 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CB4_RS05310 e1cbe875ce7633ff0dcbc69283919f31 165 Gene3D G3DSA:3.30.70.1150 90 161 1.0E-29 T 29-03-2018 CB4_RS05310 e1cbe875ce7633ff0dcbc69283919f31 165 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 4 78 2.0E-20 T 29-03-2018 CB4_RS05310 e1cbe875ce7633ff0dcbc69283919f31 165 Pfam PF01842 ACT domain 5 70 6.3E-17 T 29-03-2018 IPR002912 ACT domain CB4_RS05310 e1cbe875ce7633ff0dcbc69283919f31 165 Gene3D G3DSA:3.30.70.260 1 89 1.0E-27 T 29-03-2018 CB4_RS05310 e1cbe875ce7633ff0dcbc69283919f31 165 SUPERFAMILY SSF55021 3 77 3.14E-22 T 29-03-2018 CB4_RS05310 e1cbe875ce7633ff0dcbc69283919f31 165 SUPERFAMILY SSF55021 81 160 3.66E-25 T 29-03-2018 CB4_RS05310 e1cbe875ce7633ff0dcbc69283919f31 165 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 159 3.5E-61 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 Gene3D G3DSA:2.120.10.10 170 417 0.17 T 29-03-2018 CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 Pfam PF00395 S-layer homology domain 973 1015 4.4E-15 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 Pfam PF00395 S-layer homology domain 914 957 1.4E-10 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 Pfam PF00395 S-layer homology domain 873 896 6.4E-7 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 Pfam PF12733 Cadherin-like beta sandwich domain 320 408 2.5E-20 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 Pfam PF12733 Cadherin-like beta sandwich domain 419 507 2.7E-22 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 Pfam PF12733 Cadherin-like beta sandwich domain 518 607 6.5E-22 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 Gene3D G3DSA:2.60.420.10 428 492 0.43 T 29-03-2018 CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 SUPERFAMILY SSF110296 63 309 1.7E-13 T 29-03-2018 CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 Gene3D G3DSA:2.130.10.10 25 169 1.0E-9 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS02125 8142f59700320f5a12d757d7bf14685b 1055 Gene3D G3DSA:2.60.120.260 550 640 0.17 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS19180 d6c68e018dadc79965c8d0256c3df02a 335 SMART SM00382 49 233 1.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS19180 d6c68e018dadc79965c8d0256c3df02a 335 Gene3D G3DSA:3.40.50.300 3 261 1.9E-52 T 29-03-2018 CB4_RS19180 d6c68e018dadc79965c8d0256c3df02a 335 SUPERFAMILY SSF52540 33 252 1.43E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19180 d6c68e018dadc79965c8d0256c3df02a 335 Pfam PF00005 ABC transporter 41 184 1.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS02370 619369cd17b920ea973da5ecc1626b89 274 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 1.1E-88 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS02370 619369cd17b920ea973da5ecc1626b89 274 SUPERFAMILY SSF53613 5 271 5.46E-75 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS02370 619369cd17b920ea973da5ecc1626b89 274 Gene3D G3DSA:3.40.1190.20 3 272 5.6E-56 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS02370 619369cd17b920ea973da5ecc1626b89 274 Pfam PF08543 Phosphomethylpyrimidine kinase 13 261 1.2E-90 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CB4_RS10950 c9aedcf268f752a861c3e52d8a7ec344 310 SUPERFAMILY SSF52172 5 131 5.41E-22 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS10950 c9aedcf268f752a861c3e52d8a7ec344 310 SMART SM00448 1 114 9.5E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS10950 c9aedcf268f752a861c3e52d8a7ec344 310 Pfam PF00072 Response regulator receiver domain 5 110 4.1E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS10950 c9aedcf268f752a861c3e52d8a7ec344 310 Gene3D G3DSA:3.40.50.2300 1 248 5.2E-22 T 29-03-2018 CB4_RS10950 c9aedcf268f752a861c3e52d8a7ec344 310 Pfam PF08664 YcbB domain 160 299 6.3E-50 T 29-03-2018 IPR013972 YcbB domain CB4_RS13760 9442ef4b05bd0cda4cc040e46696a4a2 223 SUPERFAMILY SSF46894 125 222 4.25E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS13760 9442ef4b05bd0cda4cc040e46696a4a2 223 Gene3D G3DSA:1.10.10.10 120 223 2.3E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13760 9442ef4b05bd0cda4cc040e46696a4a2 223 SUPERFAMILY SSF52172 1 118 1.08E-36 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS13760 9442ef4b05bd0cda4cc040e46696a4a2 223 SMART SM00448 1 112 2.2E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13760 9442ef4b05bd0cda4cc040e46696a4a2 223 Gene3D G3DSA:3.40.50.2300 1 119 4.0E-32 T 29-03-2018 CB4_RS13760 9442ef4b05bd0cda4cc040e46696a4a2 223 Pfam PF00072 Response regulator receiver domain 3 113 6.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13760 9442ef4b05bd0cda4cc040e46696a4a2 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 6.2E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS13760 9442ef4b05bd0cda4cc040e46696a4a2 223 SMART SM00862 146 221 4.5E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS17575 da7c2bf80fd517432053d900931e6ffb 242 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 219 236 1.4E-5 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CB4_RS17575 da7c2bf80fd517432053d900931e6ffb 242 Gene3D G3DSA:3.40.50.300 1 238 5.4E-58 T 29-03-2018 CB4_RS17575 da7c2bf80fd517432053d900931e6ffb 242 SUPERFAMILY SSF52540 2 236 2.09E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS17575 da7c2bf80fd517432053d900931e6ffb 242 SMART SM00382 26 223 1.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS17575 da7c2bf80fd517432053d900931e6ffb 242 Pfam PF00005 ABC transporter 17 164 2.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS17575 da7c2bf80fd517432053d900931e6ffb 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS16760 ad6ca6568b3718e3271fe14cd9c06907 322 Gene3D G3DSA:3.30.420.40 1 122 2.6E-29 T 29-03-2018 CB4_RS16760 ad6ca6568b3718e3271fe14cd9c06907 322 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 7 317 3.3E-81 T 29-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CB4_RS16760 ad6ca6568b3718e3271fe14cd9c06907 322 Pfam PF00480 ROK family 5 317 2.6E-66 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CB4_RS16760 ad6ca6568b3718e3271fe14cd9c06907 322 Gene3D G3DSA:3.30.420.40 123 318 1.1E-51 T 29-03-2018 CB4_RS16760 ad6ca6568b3718e3271fe14cd9c06907 322 SUPERFAMILY SSF53067 1 314 6.79E-61 T 29-03-2018 CB4_RS17750 e3b29ea0674a23a1b1917d7e3f18858f 243 Gene3D G3DSA:3.30.70.1560 142 212 6.2E-23 T 29-03-2018 CB4_RS17750 e3b29ea0674a23a1b1917d7e3f18858f 243 Gene3D G3DSA:3.10.290.10 1 55 1.9E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS17750 e3b29ea0674a23a1b1917d7e3f18858f 243 SMART SM00363 1 60 1.2E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS17750 e3b29ea0674a23a1b1917d7e3f18858f 243 Pfam PF00849 RNA pseudouridylate synthase 62 195 8.0E-21 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS17750 e3b29ea0674a23a1b1917d7e3f18858f 243 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CB4_RS17750 e3b29ea0674a23a1b1917d7e3f18858f 243 SUPERFAMILY SSF55120 47 230 9.54E-46 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS17750 e3b29ea0674a23a1b1917d7e3f18858f 243 Pfam PF01479 S4 domain 1 46 2.6E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS17750 e3b29ea0674a23a1b1917d7e3f18858f 243 SUPERFAMILY SSF55174 1 59 1.06E-13 T 29-03-2018 CB4_RS17750 e3b29ea0674a23a1b1917d7e3f18858f 243 Gene3D G3DSA:3.30.70.580 56 141 2.3E-20 T 29-03-2018 CB4_RS17750 e3b29ea0674a23a1b1917d7e3f18858f 243 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 227 6.0E-47 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CB4_RS02610 0ebecce7101fff1de620162d2b3f013a 401 Pfam PF12698 ABC-2 family transporter protein 17 385 1.0E-18 T 29-03-2018 CB4_RS02610 0ebecce7101fff1de620162d2b3f013a 401 Gene3D G3DSA:3.40.1710.10 43 182 4.0E-11 T 29-03-2018 CB4_RS03545 c467b81dff89b6bf14ec781ff4f7e5d7 344 Gene3D G3DSA:3.30.360.10 159 312 3.7E-61 T 29-03-2018 CB4_RS03545 c467b81dff89b6bf14ec781ff4f7e5d7 344 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 158 315 4.9E-22 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CB4_RS03545 c467b81dff89b6bf14ec781ff4f7e5d7 344 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 140 2.8E-31 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CB4_RS03545 c467b81dff89b6bf14ec781ff4f7e5d7 344 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CB4_RS03545 c467b81dff89b6bf14ec781ff4f7e5d7 344 SUPERFAMILY SSF55347 149 312 5.18E-56 T 29-03-2018 CB4_RS03545 c467b81dff89b6bf14ec781ff4f7e5d7 344 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 344 1.2E-137 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CB4_RS03545 c467b81dff89b6bf14ec781ff4f7e5d7 344 SUPERFAMILY SSF51735 2 175 7.8E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS03545 c467b81dff89b6bf14ec781ff4f7e5d7 344 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 338 43.755 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CB4_RS03545 c467b81dff89b6bf14ec781ff4f7e5d7 344 SMART SM00859 2 141 3.7E-43 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CB4_RS03545 c467b81dff89b6bf14ec781ff4f7e5d7 344 Gene3D G3DSA:3.40.50.720 1 158 7.8E-38 T 29-03-2018 CB4_RS10295 7b15781433d0bb6cc0427ad38f4e6cc7 635 Pfam PF08439 Oligopeptidase F 150 217 1.9E-19 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CB4_RS10295 7b15781433d0bb6cc0427ad38f4e6cc7 635 Gene3D G3DSA:1.10.1370.10 114 630 3.9E-46 T 29-03-2018 CB4_RS10295 7b15781433d0bb6cc0427ad38f4e6cc7 635 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 43 630 2.4E-178 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CB4_RS10295 7b15781433d0bb6cc0427ad38f4e6cc7 635 SUPERFAMILY SSF55486 43 615 1.36E-121 T 29-03-2018 CB4_RS10295 7b15781433d0bb6cc0427ad38f4e6cc7 635 Pfam PF01432 Peptidase family M3 238 619 5.7E-71 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CB4_RS01395 b881c91657ff3db5f8af7b4c8a80b833 315 Gene3D G3DSA:3.40.50.10800 104 189 7.6E-25 T 29-03-2018 CB4_RS01395 b881c91657ff3db5f8af7b4c8a80b833 315 Gene3D G3DSA:3.40.50.10800 190 293 6.2E-34 T 29-03-2018 CB4_RS01395 b881c91657ff3db5f8af7b4c8a80b833 315 Gene3D G3DSA:3.40.50.10800 14 103 4.1E-21 T 29-03-2018 CB4_RS01395 b881c91657ff3db5f8af7b4c8a80b833 315 Pfam PF02445 Quinolinate synthetase A protein 19 309 7.3E-123 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CB4_RS01395 b881c91657ff3db5f8af7b4c8a80b833 315 Hamap MF_00568 Quinolinate synthase A [nadA]. 14 311 44.374 T 29-03-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CB4_RS01395 b881c91657ff3db5f8af7b4c8a80b833 315 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 13 311 4.8E-115 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CB4_RS01395 b881c91657ff3db5f8af7b4c8a80b833 315 SUPERFAMILY SSF142754 15 310 1.7E-120 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 Gene3D G3DSA:4.10.320.10 117 169 5.1E-19 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 Gene3D G3DSA:3.90.1170.30 1 46 8.7E-17 T 29-03-2018 CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 SUPERFAMILY SSF51230 1 94 5.89E-29 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 Gene3D G3DSA:3.90.1170.30 47 103 0.017 T 29-03-2018 CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 Gene3D G3DSA:3.30.559.10 202 445 1.0E-86 T 29-03-2018 CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 SUPERFAMILY SSF47005 122 162 4.45E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 Pfam PF00364 Biotin-requiring enzyme 4 76 1.3E-22 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 SUPERFAMILY SSF52777 211 442 3.74E-84 T 29-03-2018 CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 Pfam PF02817 e3 binding domain 124 157 3.5E-14 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS16370 02a0e7943eefd520fe7048fe4067ac8b 450 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 221 443 1.4E-80 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Pfam PF00072 Response regulator receiver domain 838 950 3.2E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SMART SM00387 693 808 6.4E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SUPERFAMILY SSF47384 571 652 1.26E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Gene3D G3DSA:3.30.450.40 296 460 3.7E-13 T 29-03-2018 IPR029016 GAF domain-like CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SUPERFAMILY SSF158472 209 258 2.75E-8 T 29-03-2018 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Pfam PF13426 PAS domain 470 577 2.3E-7 T 29-03-2018 IPR000014 PAS domain CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SMART SM00304 209 261 1.1E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SMART SM00065 313 455 4.0E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Gene3D G3DSA:3.40.50.2300 831 972 1.8E-23 T 29-03-2018 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Gene3D G3DSA:3.30.565.10 646 808 7.2E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Pfam PF00512 His Kinase A (phospho-acceptor) domain 585 651 9.5E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 PRINTS PR00344 Bacterial sensor protein C-terminal signature 733 747 1.6E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 PRINTS PR00344 Bacterial sensor protein C-terminal signature 768 786 1.6E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 PRINTS PR00344 Bacterial sensor protein C-terminal signature 792 805 1.6E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 PRINTS PR00344 Bacterial sensor protein C-terminal signature 751 761 1.6E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 463 582 1.5E-5 T 29-03-2018 IPR000014 PAS domain CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 694 806 1.2E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SUPERFAMILY SSF55781 301 466 1.02E-15 T 29-03-2018 IPR029016 GAF domain-like CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Pfam PF13185 GAF domain 313 446 1.3E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SUPERFAMILY SSF52172 837 961 6.97E-24 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SMART SM00091 459 525 0.0022 T 29-03-2018 IPR000014 PAS domain CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SMART SM00448 836 951 2.6E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Gene3D G3DSA:3.30.450.20 461 581 3.1E-16 T 29-03-2018 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Gene3D G3DSA:1.20.120.330 31 295 2.3E-5 T 29-03-2018 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Gene3D G3DSA:1.10.287.130 582 645 1.5E-20 T 29-03-2018 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 Pfam PF00672 HAMP domain 211 257 1.3E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SMART SM00388 585 651 3.1E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SUPERFAMILY SSF55785 453 577 7.15E-12 T 29-03-2018 IPR000014 PAS domain CB4_RS16990 c56c86db22d4cac6b64756bdd09e1caa 973 SUPERFAMILY SSF55874 640 810 7.99E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS17175 d5d5788f482f4891fd9ae8004edb7e1d 394 SUPERFAMILY SSF56796 4 385 4.84E-126 T 29-03-2018 CB4_RS17175 d5d5788f482f4891fd9ae8004edb7e1d 394 Gene3D G3DSA:1.20.1090.10 183 393 1.7E-61 T 29-03-2018 CB4_RS17175 d5d5788f482f4891fd9ae8004edb7e1d 394 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CB4_RS17175 d5d5788f482f4891fd9ae8004edb7e1d 394 Gene3D G3DSA:3.40.50.1970 9 182 1.3E-50 T 29-03-2018 CB4_RS17175 d5d5788f482f4891fd9ae8004edb7e1d 394 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 377 4.8E-125 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CB4_RS17255 75d7f364180626f124ff2f8854fb6f63 148 Gene3D G3DSA:1.10.1660.10 1 58 1.1E-21 T 29-03-2018 CB4_RS17255 75d7f364180626f124ff2f8854fb6f63 148 SMART SM00422 3 73 1.6E-26 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS17255 75d7f364180626f124ff2f8854fb6f63 148 SUPERFAMILY SSF46955 3 127 2.6E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS17255 75d7f364180626f124ff2f8854fb6f63 148 Pfam PF13411 MerR HTH family regulatory protein 3 71 3.5E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS17255 75d7f364180626f124ff2f8854fb6f63 148 Gene3D G3DSA:1.10.1660.10 59 147 4.1E-8 T 29-03-2018 CB4_RS17815 fff153c8722b1af1b7a282fd8c673a4d 529 SUPERFAMILY SSF55486 3 527 2.75E-72 T 29-03-2018 CB4_RS17815 fff153c8722b1af1b7a282fd8c673a4d 529 Gene3D G3DSA:1.10.1370.10 317 527 2.2E-27 T 29-03-2018 CB4_RS17815 fff153c8722b1af1b7a282fd8c673a4d 529 Gene3D G3DSA:1.10.1370.10 5 256 6.3E-14 T 29-03-2018 CB4_RS17815 fff153c8722b1af1b7a282fd8c673a4d 529 Pfam PF01401 Angiotensin-converting enzyme 4 474 8.4E-15 T 29-03-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 CB4_RS11030 6e58f2b6790239ae2c6086e3ac70fa43 244 PIRSF PIRSF031509 4 244 4.4E-56 T 29-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 CB4_RS11030 6e58f2b6790239ae2c6086e3ac70fa43 244 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 128 241 1.8E-36 T 29-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CB4_RS05565 d79ec4cbc73c2eb8436d820af86dd80d 73 SUPERFAMILY SSF46894 6 70 1.29E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS05565 d79ec4cbc73c2eb8436d820af86dd80d 73 ProSitePatterns PS00622 LuxR-type HTH domain signature. 25 52 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS05565 d79ec4cbc73c2eb8436d820af86dd80d 73 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 41 53 2.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS05565 d79ec4cbc73c2eb8436d820af86dd80d 73 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 11 25 2.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS05565 d79ec4cbc73c2eb8436d820af86dd80d 73 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 25 41 2.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS05565 d79ec4cbc73c2eb8436d820af86dd80d 73 SMART SM00421 8 65 9.0E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS05565 d79ec4cbc73c2eb8436d820af86dd80d 73 Gene3D G3DSA:1.10.10.10 1 73 8.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS05565 d79ec4cbc73c2eb8436d820af86dd80d 73 Pfam PF00196 Bacterial regulatory proteins, luxR family 11 63 1.6E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS04145 ea2579cac6d83f62ded37abf97eec93c 346 Gene3D G3DSA:3.40.50.2300 165 304 1.1E-16 T 29-03-2018 CB4_RS04145 ea2579cac6d83f62ded37abf97eec93c 346 SUPERFAMILY SSF53822 51 305 1.81E-12 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS04145 ea2579cac6d83f62ded37abf97eec93c 346 Pfam PF04392 ABC transporter substrate binding protein 44 325 3.3E-88 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein CB4_RS04145 ea2579cac6d83f62ded37abf97eec93c 346 Gene3D G3DSA:3.40.50.2300 40 164 6.8E-19 T 29-03-2018 CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 Pfam PF00994 Probable molybdopterin binding domain 190 326 2.1E-21 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 176 9.7E-41 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 SUPERFAMILY SSF63882 7 184 1.57E-51 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 Gene3D G3DSA:2.170.190.11 50 150 4.7E-24 T 29-03-2018 CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 Gene3D G3DSA:3.40.980.10 159 334 1.6E-49 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 SMART SM00852 189 327 1.2E-36 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 SUPERFAMILY SSF53218 186 331 9.29E-36 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 Gene3D G3DSA:2.40.340.10 338 412 1.1E-15 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 Pfam PF03454 MoeA C-terminal region (domain IV) 340 411 3.6E-17 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 SUPERFAMILY SSF63867 338 411 6.67E-15 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CB4_RS12550 20f25461a3aa33dc51dafa422cc5e775 417 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 323 6.4E-26 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS18130 680da0572e729f1968c1cdb4c5c650a5 355 Gene3D G3DSA:1.10.3210.10 108 303 6.3E-34 T 29-03-2018 CB4_RS18130 680da0572e729f1968c1cdb4c5c650a5 355 SUPERFAMILY SSF109604 133 295 8.7E-26 T 29-03-2018 CB4_RS18130 680da0572e729f1968c1cdb4c5c650a5 355 Pfam PF13487 HD domain 191 251 6.4E-17 T 29-03-2018 CB4_RS18130 680da0572e729f1968c1cdb4c5c650a5 355 TIGRFAM TIGR00277 HDIG: HDIG domain 137 229 4.5E-8 T 29-03-2018 IPR006675 HDIG domain CB4_RS02090 60d09aae545133623deab1f660e0e375 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02090 60d09aae545133623deab1f660e0e375 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02090 60d09aae545133623deab1f660e0e375 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02090 60d09aae545133623deab1f660e0e375 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02090 60d09aae545133623deab1f660e0e375 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02090 60d09aae545133623deab1f660e0e375 281 SUPERFAMILY SSF51735 2 247 8.74E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS02090 60d09aae545133623deab1f660e0e375 281 Pfam PF00106 short chain dehydrogenase 6 196 1.3E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02090 60d09aae545133623deab1f660e0e375 281 PIRSF PIRSF000126 1 260 3.4E-79 T 29-03-2018 CB4_RS02090 60d09aae545133623deab1f660e0e375 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02090 60d09aae545133623deab1f660e0e375 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02090 60d09aae545133623deab1f660e0e375 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02090 60d09aae545133623deab1f660e0e375 281 Gene3D G3DSA:3.40.50.720 2 278 8.8E-52 T 29-03-2018 CB4_RS14570 870b9011a1ed36b0bcdd27e349f5e88d 288 Pfam PF05368 NmrA-like family 2 221 4.3E-24 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CB4_RS14570 870b9011a1ed36b0bcdd27e349f5e88d 288 SUPERFAMILY SSF51735 2 249 3.54E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS14570 870b9011a1ed36b0bcdd27e349f5e88d 288 Gene3D G3DSA:3.40.50.720 1 288 2.1E-24 T 29-03-2018 CB4_RS09320 cfae3c84d0787a4d7d128b0863e875cc 91 Pfam PF04296 Protein of unknown function (DUF448) 9 83 1.7E-26 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CB4_RS09320 cfae3c84d0787a4d7d128b0863e875cc 91 SUPERFAMILY SSF64376 4 88 4.05E-27 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CB4_RS09320 cfae3c84d0787a4d7d128b0863e875cc 91 Gene3D G3DSA:3.30.1230.10 1 91 2.6E-29 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CB4_RS02845 82ad26ee78baa990bbb1c21e4c3197b2 66 PRINTS PR01249 Ribosomal protein L31 signature 45 63 7.6E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS02845 82ad26ee78baa990bbb1c21e4c3197b2 66 PRINTS PR01249 Ribosomal protein L31 signature 30 45 7.6E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS02845 82ad26ee78baa990bbb1c21e4c3197b2 66 PRINTS PR01249 Ribosomal protein L31 signature 2 19 7.6E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS02845 82ad26ee78baa990bbb1c21e4c3197b2 66 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS02845 82ad26ee78baa990bbb1c21e4c3197b2 66 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 2.3E-32 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS02845 82ad26ee78baa990bbb1c21e4c3197b2 66 SUPERFAMILY SSF143800 1 65 2.86E-26 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02845 82ad26ee78baa990bbb1c21e4c3197b2 66 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 66 29.036 T 29-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS02845 82ad26ee78baa990bbb1c21e4c3197b2 66 Pfam PF01197 Ribosomal protein L31 1 64 8.8E-32 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS19605 dfe8d84be68cb2271c5491e27bf0eaf5 338 Gene3D G3DSA:2.40.10.10 72 216 1.3E-8 T 29-03-2018 CB4_RS19605 dfe8d84be68cb2271c5491e27bf0eaf5 338 SUPERFAMILY SSF50494 149 325 3.04E-23 T 29-03-2018 IPR009003 Peptidase S1, PA clan CB4_RS19605 dfe8d84be68cb2271c5491e27bf0eaf5 338 Gene3D G3DSA:2.40.10.10 223 329 1.6E-10 T 29-03-2018 CB4_RS19605 dfe8d84be68cb2271c5491e27bf0eaf5 338 Pfam PF13365 Trypsin-like peptidase domain 159 292 2.6E-13 T 29-03-2018 CB4_RS19605 dfe8d84be68cb2271c5491e27bf0eaf5 338 PRINTS PR00839 V8 serine protease family signature 159 176 1.5E-7 T 29-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CB4_RS19605 dfe8d84be68cb2271c5491e27bf0eaf5 338 PRINTS PR00839 V8 serine protease family signature 267 283 1.5E-7 T 29-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CB4_RS04390 c2b4849a15d7dcc034088123aaf93e87 277 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 268 1.5E-36 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CB4_RS04390 c2b4849a15d7dcc034088123aaf93e87 277 SUPERFAMILY SSF48179 164 270 3.23E-35 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS04390 c2b4849a15d7dcc034088123aaf93e87 277 SUPERFAMILY SSF51735 5 162 1.2E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS04390 c2b4849a15d7dcc034088123aaf93e87 277 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 101 1.1E-17 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CB4_RS04390 c2b4849a15d7dcc034088123aaf93e87 277 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 268 25.732 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CB4_RS04390 c2b4849a15d7dcc034088123aaf93e87 277 PIRSF PIRSF000193 4 271 3.5E-74 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CB4_RS04390 c2b4849a15d7dcc034088123aaf93e87 277 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 268 5.4E-81 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CB4_RS04390 c2b4849a15d7dcc034088123aaf93e87 277 Gene3D G3DSA:1.10.3730.10 167 273 2.3E-40 T 29-03-2018 CB4_RS04390 c2b4849a15d7dcc034088123aaf93e87 277 Gene3D G3DSA:3.40.50.720 2 166 9.1E-24 T 29-03-2018 CB4_RS04840 6779f92747e2bb8084bb97cf24e4963a 556 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 2 554 1.0E-224 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CB4_RS04840 6779f92747e2bb8084bb97cf24e4963a 556 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 555 34.101 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CB4_RS04840 6779f92747e2bb8084bb97cf24e4963a 556 PIRSF PIRSF001294 1 556 2.9E-247 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CB4_RS04840 6779f92747e2bb8084bb97cf24e4963a 556 Pfam PF03814 Potassium-transporting ATPase A subunit 9 553 7.9E-246 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CB4_RS20755 0ef3dc2788a852bada2b0d85896ff1bc 444 Gene3D G3DSA:3.90.1150.10 9 159 1.7E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS20755 0ef3dc2788a852bada2b0d85896ff1bc 444 SUPERFAMILY SSF53383 17 438 1.16E-121 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS20755 0ef3dc2788a852bada2b0d85896ff1bc 444 Gene3D G3DSA:3.90.1150.10 254 441 6.8E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS20755 0ef3dc2788a852bada2b0d85896ff1bc 444 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS20755 0ef3dc2788a852bada2b0d85896ff1bc 444 Gene3D G3DSA:3.90.1150.10 184 253 0.1 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS20755 0ef3dc2788a852bada2b0d85896ff1bc 444 Pfam PF00202 Aminotransferase class-III 22 437 7.7E-103 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS20755 0ef3dc2788a852bada2b0d85896ff1bc 444 PIRSF PIRSF000521 19 440 4.0E-42 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS01085 85ead56d81f77e8fe3632d2ccaa8f517 75 Pfam PF00462 Glutaredoxin 3 61 2.0E-11 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CB4_RS01085 85ead56d81f77e8fe3632d2ccaa8f517 75 Gene3D G3DSA:3.40.30.10 1 75 9.6E-19 T 29-03-2018 CB4_RS01085 85ead56d81f77e8fe3632d2ccaa8f517 75 SUPERFAMILY SSF52833 1 73 3.9E-17 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS06265 9f6ff726113c7a628eb6496d4a0bda76 220 Gene3D G3DSA:2.30.110.10 3 96 3.0E-11 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS06265 9f6ff726113c7a628eb6496d4a0bda76 220 Gene3D G3DSA:2.40.10.220 97 217 9.6E-21 T 29-03-2018 CB4_RS06265 9f6ff726113c7a628eb6496d4a0bda76 220 Pfam PF07238 PilZ domain 97 207 8.4E-13 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CB4_RS06265 9f6ff726113c7a628eb6496d4a0bda76 220 SUPERFAMILY SSF141371 123 207 3.92E-7 T 29-03-2018 CB4_RS06265 9f6ff726113c7a628eb6496d4a0bda76 220 Pfam PF12945 Flagellar protein YcgR 9 88 9.0E-11 T 29-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal CB4_RS09350 67f420aec2051e9027234efc450c8094 314 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 20 308 5.9E-92 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CB4_RS09350 67f420aec2051e9027234efc450c8094 314 Pfam PF06574 FAD synthetase 17 166 4.7E-46 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CB4_RS09350 67f420aec2051e9027234efc450c8094 314 Gene3D G3DSA:2.40.30.30 180 313 5.7E-43 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CB4_RS09350 67f420aec2051e9027234efc450c8094 314 PIRSF PIRSF004491 5 313 4.7E-102 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CB4_RS09350 67f420aec2051e9027234efc450c8094 314 SUPERFAMILY SSF52374 18 176 2.82E-31 T 29-03-2018 CB4_RS09350 67f420aec2051e9027234efc450c8094 314 SUPERFAMILY SSF82114 174 309 3.49E-45 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CB4_RS09350 67f420aec2051e9027234efc450c8094 314 SMART SM00904 183 309 3.5E-61 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CB4_RS09350 67f420aec2051e9027234efc450c8094 314 Pfam PF01687 Riboflavin kinase 184 308 4.4E-39 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CB4_RS09350 67f420aec2051e9027234efc450c8094 314 Gene3D G3DSA:3.40.50.620 11 179 2.0E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS00500 c4c652783035610f8db6286d7a150653 556 Pfam PF17392 Urocanase C-terminal domain 351 545 1.1E-95 T 29-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00500 c4c652783035610f8db6286d7a150653 556 Hamap MF_00577 Urocanate hydratase [hutU]. 5 555 50.519 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00500 c4c652783035610f8db6286d7a150653 556 SUPERFAMILY SSF111326 7 554 1.7E-260 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00500 c4c652783035610f8db6286d7a150653 556 Gene3D G3DSA:3.40.1770.10 195 554 1.5E-165 T 29-03-2018 CB4_RS00500 c4c652783035610f8db6286d7a150653 556 Gene3D G3DSA:3.40.1770.10 10 152 1.9E-28 T 29-03-2018 CB4_RS00500 c4c652783035610f8db6286d7a150653 556 PIRSF PIRSF001423 2 556 3.1E-296 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00500 c4c652783035610f8db6286d7a150653 556 TIGRFAM TIGR01228 hutU: urocanate hydratase 10 553 5.6E-303 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00500 c4c652783035610f8db6286d7a150653 556 ProSitePatterns PS01233 Urocanase signature. 441 456 - T 29-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00500 c4c652783035610f8db6286d7a150653 556 Pfam PF01175 Urocanase Rossmann-like domain 140 348 5.5E-90 T 29-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00500 c4c652783035610f8db6286d7a150653 556 Pfam PF17391 Urocanase N-terminal domain 12 137 4.0E-61 T 29-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS16640 84b20584f5b04d067e464a709d9901ef 497 Gene3D G3DSA:2.30.38.10 316 397 3.5E-29 T 29-03-2018 CB4_RS16640 84b20584f5b04d067e464a709d9901ef 497 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 488 9.0E-23 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS16640 84b20584f5b04d067e464a709d9901ef 497 Pfam PF00501 AMP-binding enzyme 14 405 2.7E-114 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS16640 84b20584f5b04d067e464a709d9901ef 497 ProSitePatterns PS00455 Putative AMP-binding domain signature. 159 170 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS16640 84b20584f5b04d067e464a709d9901ef 497 SUPERFAMILY SSF56801 14 496 2.49E-160 T 29-03-2018 CB4_RS16640 84b20584f5b04d067e464a709d9901ef 497 Gene3D G3DSA:3.40.50.980 11 163 1.1E-40 T 29-03-2018 CB4_RS16640 84b20584f5b04d067e464a709d9901ef 497 Gene3D G3DSA:3.40.50.980 164 315 7.9E-51 T 29-03-2018 CB4_RS16640 84b20584f5b04d067e464a709d9901ef 497 Gene3D G3DSA:3.30.300.30 398 497 1.0E-28 T 29-03-2018 CB4_RS05815 d5aefd96e3d6799eb68b7a751f1e5853 306 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 8 279 5.3E-48 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CB4_RS05815 d5aefd96e3d6799eb68b7a751f1e5853 306 Gene3D G3DSA:1.20.5.340 65 190 5.3E-4 T 29-03-2018 CB4_RS05815 d5aefd96e3d6799eb68b7a751f1e5853 306 Pfam PF04085 rod shape-determining protein MreC 124 277 1.2E-41 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CB4_RS05815 d5aefd96e3d6799eb68b7a751f1e5853 306 PIRSF PIRSF038471 2 291 1.9E-62 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CB4_RS10945 b414581c0bc24454e1ced4552ec41c55 419 SUPERFAMILY SSF55874 265 411 4.32E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10945 b414581c0bc24454e1ced4552ec41c55 419 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 413 6.2E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10945 b414581c0bc24454e1ced4552ec41c55 419 Gene3D G3DSA:3.30.565.10 159 413 5.8E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10945 b414581c0bc24454e1ced4552ec41c55 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 353 2.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10945 b414581c0bc24454e1ced4552ec41c55 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 367 2.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10945 b414581c0bc24454e1ced4552ec41c55 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 2.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10945 b414581c0bc24454e1ced4552ec41c55 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 2.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10945 b414581c0bc24454e1ced4552ec41c55 419 SMART SM00387 302 414 1.9E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 SMART SM00420 8 60 1.6E-19 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 Gene3D G3DSA:3.40.50.1360 75 246 8.3E-40 T 29-03-2018 CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 Pfam PF00455 DeoR C terminal sensor domain 77 240 3.2E-49 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 SUPERFAMILY SSF46785 6 72 1.59E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 4.5E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 4.5E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 Pfam PF08220 DeoR-like helix-turn-helix domain 8 59 1.2E-17 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 SMART SM01134 75 241 1.6E-66 T 29-03-2018 CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 SUPERFAMILY SSF100950 77 241 5.96E-33 T 29-03-2018 CB4_RS10155 f1074380b0203359a6be6550fa9f7d1e 260 Gene3D G3DSA:1.10.10.10 5 64 4.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 SUPERFAMILY SSF118215 6 402 3.27E-128 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 Gene3D G3DSA:1.10.3860.10 1 408 3.6E-132 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 1.1E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 1.1E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.1E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 1.1E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 1.1E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 1.1E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 1.1E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 2.1E-126 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS12395 b0e0917f6208fd093e2de53aa1c645fc 424 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 SUPERFAMILY SSF110296 28 232 1.46E-11 T 29-03-2018 CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 SUPERFAMILY SSF110296 357 641 9.68E-15 T 29-03-2018 CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 Gene3D G3DSA:2.130.10.10 401 598 1.4E-10 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 Gene3D G3DSA:2.130.10.10 199 400 4.3E-8 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 SUPERFAMILY SSF110296 169 431 2.75E-14 T 29-03-2018 CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 Gene3D G3DSA:2.130.10.10 23 191 7.3E-9 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 582 657 1.4E-15 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 746 821 3.6E-12 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 665 739 1.7E-13 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 619 661 8.2E-9 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 784 824 5.5E-6 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 701 743 8.1E-7 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 Pfam PF00395 S-layer homology domain 1069 1110 4.1E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 Pfam PF00395 S-layer homology domain 1127 1169 1.3E-13 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02120 c651e9de1454dfef0cd14a85c76524a2 1260 Pfam PF00395 S-layer homology domain 1202 1239 4.6E-5 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.2E-28 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 2.2E-28 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.2E-28 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 2.2E-28 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 2.0E-19 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 70.538 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 SUPERFAMILY SSF46785 3 78 1.27E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 Gene3D G3DSA:1.10.10.10 3 66 8.6E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 148 1.2E-54 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 4.5E-31 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 SUPERFAMILY SSF55252 80 149 3.14E-22 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 Pfam PF02863 Arginine repressor, C-terminal domain 82 145 5.4E-27 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CB4_RS08000 9cf08065bde9a2bf2e206f44267663c1 149 Gene3D G3DSA:3.30.1360.40 74 146 3.1E-29 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 TIGRFAM TIGR01083 nth: endonuclease III 6 196 1.7E-85 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 1.4E-5 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 PIRSF PIRSF001435 2 214 1.3E-56 T 29-03-2018 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 Pfam PF00633 Helix-hairpin-helix motif 100 128 3.8E-6 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 170 1.6E-26 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 Hamap MF_00942 Endonuclease III [nth]. 1 211 39.943 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 SUPERFAMILY SSF48150 3 212 2.51E-74 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 SMART SM00525 188 208 0.0023 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 SMART SM00478 39 187 2.1E-68 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 Gene3D G3DSA:1.10.340.30 22 118 3.2E-28 T 29-03-2018 CB4_RS10430 eca713fa1c61686685d3dabcf20836b1 219 Gene3D G3DSA:1.10.1670.10 119 219 3.0E-33 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 7.4E-56 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 SMART SM01382 124 253 2.5E-91 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 Gene3D G3DSA:2.30.30.30 119 195 2.0E-33 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 PIRSF PIRSF002158 3 276 1.7E-99 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 SMART SM01383 42 118 5.2E-49 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 Gene3D G3DSA:4.10.950.10 197 275 9.8E-34 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.1E-35 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 8.2E-138 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 49.574 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 SUPERFAMILY SSF50249 2 125 8.57E-53 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 Gene3D G3DSA:2.40.50.140 1 114 5.8E-52 T 29-03-2018 CB4_RS00940 9299b13ec2a3fe00c05b131ac41252d8 276 SUPERFAMILY SSF50104 126 272 2.71E-59 T 29-03-2018 IPR008991 Translation protein SH3-like domain CB4_RS04960 a22c0ddd0054e43e656c6bc02d3970e4 341 SUPERFAMILY SSF51261 151 324 1.83E-33 T 29-03-2018 IPR011055 Duplicated hybrid motif CB4_RS04960 a22c0ddd0054e43e656c6bc02d3970e4 341 Pfam PF01551 Peptidase family M23 213 310 2.1E-21 T 29-03-2018 IPR016047 Peptidase M23 CB4_RS04960 a22c0ddd0054e43e656c6bc02d3970e4 341 SUPERFAMILY SSF53955 33 182 7.87E-7 T 29-03-2018 IPR023346 Lysozyme-like domain CB4_RS04960 a22c0ddd0054e43e656c6bc02d3970e4 341 Gene3D G3DSA:2.70.70.10 193 341 1.5E-30 T 29-03-2018 CB4_RS04960 a22c0ddd0054e43e656c6bc02d3970e4 341 Gene3D G3DSA:1.10.530.10 24 192 7.1E-7 T 29-03-2018 CB4_RS09885 5c70992f996ee837e24cb4b1f32e998d 488 PIRSF PIRSF000331 1 487 1.0E-137 T 29-03-2018 IPR004925 HpaB/PvcC/4-BUDH CB4_RS09885 5c70992f996ee837e24cb4b1f32e998d 488 Gene3D G3DSA:1.20.140.10 284 478 5.6E-54 T 29-03-2018 CB4_RS09885 5c70992f996ee837e24cb4b1f32e998d 488 SUPERFAMILY SSF47203 262 478 6.7E-45 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS09885 5c70992f996ee837e24cb4b1f32e998d 488 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 271 5.0E-96 T 29-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal CB4_RS09885 5c70992f996ee837e24cb4b1f32e998d 488 SUPERFAMILY SSF56645 3 271 8.33E-78 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CB4_RS09885 5c70992f996ee837e24cb4b1f32e998d 488 Gene3D G3DSA:2.40.110.10 145 273 7.0E-19 T 29-03-2018 CB4_RS09885 5c70992f996ee837e24cb4b1f32e998d 488 Gene3D G3DSA:1.10.3140.10 3 144 1.0E-44 T 29-03-2018 CB4_RS09885 5c70992f996ee837e24cb4b1f32e998d 488 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 292 477 1.5E-49 T 29-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal CB4_RS02630 d4aa921e039fcda938acee89175a0890 283 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 13 275 2.4E-52 T 29-03-2018 IPR017039 Virulence factor BrkB CB4_RS02630 d4aa921e039fcda938acee89175a0890 283 PIRSF PIRSF035875 3 283 9.1E-77 T 29-03-2018 IPR017039 Virulence factor BrkB CB4_RS02630 d4aa921e039fcda938acee89175a0890 283 Pfam PF03631 Virulence factor BrkB 23 274 2.8E-68 T 29-03-2018 IPR017039 Virulence factor BrkB CB4_RS17335 2633b50c68ff438651dd7d898127b295 718 Gene3D G3DSA:3.10.20.30 388 475 0.018 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS17335 2633b50c68ff438651dd7d898127b295 718 Gene3D G3DSA:3.10.20.30 537 600 0.058 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS17335 2633b50c68ff438651dd7d898127b295 718 Gene3D G3DSA:3.10.20.30 476 536 0.0048 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS17335 2633b50c68ff438651dd7d898127b295 718 SUPERFAMILY SSF53067 9 204 7.92E-27 T 29-03-2018 CB4_RS17335 2633b50c68ff438651dd7d898127b295 718 SUPERFAMILY SSF53067 215 385 8.87E-28 T 29-03-2018 CB4_RS17335 2633b50c68ff438651dd7d898127b295 718 Gene3D G3DSA:3.30.420.40 1 199 4.3E-25 T 29-03-2018 CB4_RS17335 2633b50c68ff438651dd7d898127b295 718 Pfam PF14450 Cell division protein FtsA 219 380 2.6E-12 T 29-03-2018 CB4_RS17335 2633b50c68ff438651dd7d898127b295 718 Gene3D G3DSA:3.30.420.40 215 353 4.6E-19 T 29-03-2018 CB4_RS17335 2633b50c68ff438651dd7d898127b295 718 SMART SM00842 9 208 1.4E-51 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CB4_RS18600 f8cf2b50daa11af31b715b4c6d23c643 316 Gene3D G3DSA:3.40.50.1820 2 313 9.5E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS18600 f8cf2b50daa11af31b715b4c6d23c643 316 Pfam PF12146 Serine aminopeptidase, S33 54 273 1.8E-17 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CB4_RS18600 f8cf2b50daa11af31b715b4c6d23c643 316 SUPERFAMILY SSF53474 3 146 1.07E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS18600 f8cf2b50daa11af31b715b4c6d23c643 316 SUPERFAMILY SSF53474 192 313 1.07E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 SUPERFAMILY SSF50965 78 287 6.93E-9 T 29-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 973 1016 5.9E-7 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 801 843 3.3E-7 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 887 929 4.0E-7 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Gene3D G3DSA:2.60.40.10 588 676 2.2E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Pfam PF00041 Fibronectin type III domain 596 669 3.4E-7 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Pfam PF00395 S-layer homology domain 1305 1347 4.7E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Pfam PF00395 S-layer homology domain 1242 1286 1.8E-15 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Pfam PF00395 S-layer homology domain 1183 1225 5.9E-16 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Gene3D G3DSA:2.130.10.10 60 154 9.7E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 SUPERFAMILY SSF50978 342 595 1.1E-12 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 936 1011 1.6E-13 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 850 925 1.6E-13 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 764 839 1.2E-13 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Gene3D G3DSA:2.120.10.30 383 586 1.2E-9 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 SMART SM00060 594 666 9.7E-11 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 Gene3D G3DSA:2.130.10.10 171 329 7.3E-7 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS20135 3f981602963fa8826cf5f912c4269962 1362 SUPERFAMILY SSF49265 595 678 2.27E-14 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CB4_RS19710 a8812111b6d48ced6aad686a67eac359 260 Pfam PF00561 alpha/beta hydrolase fold 22 246 7.2E-26 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS19710 a8812111b6d48ced6aad686a67eac359 260 Gene3D G3DSA:3.40.50.1820 1 260 1.2E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS19710 a8812111b6d48ced6aad686a67eac359 260 SUPERFAMILY SSF53474 3 259 2.03E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS19710 a8812111b6d48ced6aad686a67eac359 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 3.7E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS19710 a8812111b6d48ced6aad686a67eac359 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 3.7E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS19710 a8812111b6d48ced6aad686a67eac359 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 3.7E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS19710 a8812111b6d48ced6aad686a67eac359 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 3.7E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS08665 3db3c0f48c9f5d3ea7bcb6daec23add9 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 3.1E-35 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08665 3db3c0f48c9f5d3ea7bcb6daec23add9 90 Pfam PF00886 Ribosomal protein S16 9 67 6.7E-27 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08665 3db3c0f48c9f5d3ea7bcb6daec23add9 90 SUPERFAMILY SSF54565 2 86 1.07E-35 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08665 3db3c0f48c9f5d3ea7bcb6daec23add9 90 Gene3D G3DSA:3.30.1320.10 2 85 5.2E-35 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08665 3db3c0f48c9f5d3ea7bcb6daec23add9 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.567 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 Gene3D G3DSA:1.20.120.140 1 113 4.9E-20 T 29-03-2018 CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 Pfam PF02881 SRP54-type protein, helical bundle domain 34 98 5.1E-13 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 SMART SM00962 118 319 5.3E-126 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 292 305 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 SUPERFAMILY SSF47364 19 95 2.49E-17 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 Gene3D G3DSA:3.40.50.300 114 320 1.6E-42 T 29-03-2018 CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 318 1.6E-117 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 Pfam PF00448 SRP54-type protein, GTPase domain 119 318 5.2E-83 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 SMART SM00382 117 318 1.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 SUPERFAMILY SSF52540 109 318 7.99E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 SMART SM00963 22 102 5.4E-19 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08650 269b775f07c83c322fca960bdbbb8a4a 332 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 45 319 63.716 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CB4_RS14375 38e228176a1f751f8108fdbf3fb93acc 161 Pfam PF14526 Integron-associated effector binding protein 5 160 2.2E-31 T 29-03-2018 IPR029441 Integron-associated effector binding protein CB4_RS14375 38e228176a1f751f8108fdbf3fb93acc 161 Gene3D G3DSA:3.20.80.10 1 161 1.8E-45 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CB4_RS14375 38e228176a1f751f8108fdbf3fb93acc 161 SUPERFAMILY SSF55136 4 160 1.78E-23 T 29-03-2018 CB4_RS14375 38e228176a1f751f8108fdbf3fb93acc 161 SMART SM00871 2 161 8.5E-31 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CB4_RS07730 8a4cb11f7d820e0cc7466ed806f8ebdb 500 SUPERFAMILY SSF51905 6 67 6.73E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS07730 8a4cb11f7d820e0cc7466ed806f8ebdb 500 SUPERFAMILY SSF51905 116 325 6.73E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS07730 8a4cb11f7d820e0cc7466ed806f8ebdb 500 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 491 54.489 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CB4_RS07730 8a4cb11f7d820e0cc7466ed806f8ebdb 500 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 489 2.3E-220 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CB4_RS07730 8a4cb11f7d820e0cc7466ed806f8ebdb 500 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 491 7.9E-241 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CB4_RS07730 8a4cb11f7d820e0cc7466ed806f8ebdb 500 Gene3D G3DSA:3.50.50.60 1 441 2.0E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS08380 1476c777e104f82632c65c18f798cb0d 456 Pfam PF00860 Permease family 17 403 1.2E-91 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CB4_RS08380 1476c777e104f82632c65c18f798cb0d 456 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 351 371 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CB4_RS08380 1476c777e104f82632c65c18f798cb0d 456 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 14 436 7.5E-110 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 Gene3D G3DSA:3.30.70.260 336 407 3.1E-12 T 29-03-2018 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 Gene3D G3DSA:3.40.1160.10 1 239 1.3E-63 T 29-03-2018 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 Gene3D G3DSA:3.30.70.260 240 335 2.3E-17 T 29-03-2018 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 SUPERFAMILY SSF55021 261 347 6.79E-14 T 29-03-2018 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 Pfam PF13840 ACT domain 338 399 4.6E-20 T 29-03-2018 IPR027795 GATS-like ACT domain CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 SUPERFAMILY SSF55021 337 405 1.37E-15 T 29-03-2018 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 SUPERFAMILY SSF53633 4 246 2.49E-68 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 PIRSF PIRSF000726 58 407 4.0E-88 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 PIRSF PIRSF000726 1 65 3.6E-8 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 403 2.5E-127 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 61 401 6.0E-94 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS09445 9d3bdee55c7bd6997643d479e1b7d275 408 Pfam PF00696 Amino acid kinase family 3 235 1.7E-47 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS05770 c4e947a954cdd48f99dbe91d4af2d1ac 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 47 65 3.3E-8 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CB4_RS05770 c4e947a954cdd48f99dbe91d4af2d1ac 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 11 36 3.3E-8 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CB4_RS05770 c4e947a954cdd48f99dbe91d4af2d1ac 147 SUPERFAMILY SSF54523 13 122 1.52E-16 T 29-03-2018 CB4_RS05770 c4e947a954cdd48f99dbe91d4af2d1ac 147 Gene3D G3DSA:3.30.700.10 13 144 3.5E-17 T 29-03-2018 CB4_RS05770 c4e947a954cdd48f99dbe91d4af2d1ac 147 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 32 1.7E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS05770 c4e947a954cdd48f99dbe91d4af2d1ac 147 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS05770 c4e947a954cdd48f99dbe91d4af2d1ac 147 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 31 9.2E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS17720 b97fe259d5223d4dab8142e8e1a47249 295 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CB4_RS17720 b97fe259d5223d4dab8142e8e1a47249 295 Gene3D G3DSA:3.40.50.720 2 164 1.1E-33 T 29-03-2018 CB4_RS17720 b97fe259d5223d4dab8142e8e1a47249 295 PIRSF PIRSF000103 1 295 3.7E-87 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CB4_RS17720 b97fe259d5223d4dab8142e8e1a47249 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 281 6.3E-24 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CB4_RS17720 b97fe259d5223d4dab8142e8e1a47249 295 Gene3D G3DSA:1.10.1040.10 165 292 1.3E-27 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CB4_RS17720 b97fe259d5223d4dab8142e8e1a47249 295 SUPERFAMILY SSF51735 3 164 3.13E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS17720 b97fe259d5223d4dab8142e8e1a47249 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 160 6.8E-46 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CB4_RS17720 b97fe259d5223d4dab8142e8e1a47249 295 SUPERFAMILY SSF48179 165 292 1.25E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS03555 e82336009222c67624e474d7b4f928b9 391 Gene3D G3DSA:3.40.640.10 47 277 4.3E-80 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS03555 e82336009222c67624e474d7b4f928b9 391 PIRSF PIRSF000521 11 151 1.9E-11 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS03555 e82336009222c67624e474d7b4f928b9 391 PIRSF PIRSF000521 160 387 9.6E-41 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS03555 e82336009222c67624e474d7b4f928b9 391 Pfam PF00202 Aminotransferase class-III 10 384 3.0E-124 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS03555 e82336009222c67624e474d7b4f928b9 391 SUPERFAMILY SSF53383 4 385 9.38E-133 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS03555 e82336009222c67624e474d7b4f928b9 391 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 384 9.9E-155 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CB4_RS03555 e82336009222c67624e474d7b4f928b9 391 Gene3D G3DSA:3.90.1150.10 278 391 1.1E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS03555 e82336009222c67624e474d7b4f928b9 391 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 210 247 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS03555 e82336009222c67624e474d7b4f928b9 391 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 385 46.982 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Pfam PF08238 Sel1 repeat 114 147 5.2E-9 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Pfam PF08238 Sel1 repeat 293 327 3.3E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Pfam PF08238 Sel1 repeat 222 256 3.0E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Pfam PF08238 Sel1 repeat 257 290 7.3E-7 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Pfam PF08238 Sel1 repeat 186 220 1.7E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Pfam PF08238 Sel1 repeat 150 183 1.3E-5 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Pfam PF08238 Sel1 repeat 330 364 1.2E-11 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Pfam PF08238 Sel1 repeat 78 112 2.2E-7 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 SUPERFAMILY SSF81901 204 368 2.35E-56 T 29-03-2018 CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Gene3D G3DSA:2.60.40.1180 54 144 3.3E-25 T 29-03-2018 CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Gene3D G3DSA:2.60.40.1180 145 210 2.2E-24 T 29-03-2018 CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Gene3D G3DSA:2.60.40.1180 211 284 5.0E-31 T 29-03-2018 CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 Gene3D G3DSA:2.60.40.1180 285 377 4.5E-30 T 29-03-2018 CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 SUPERFAMILY SSF81901 62 228 3.84E-48 T 29-03-2018 CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 SMART SM00671 221 256 1.8E-12 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 SMART SM00671 77 112 1.6E-8 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 SMART SM00671 293 328 1.1E-12 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 SMART SM00671 329 364 2.4E-13 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 SMART SM00671 185 220 3.0E-12 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 SMART SM00671 149 184 3.7E-7 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 SMART SM00671 113 148 9.7E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS18885 c5767304b796d48c003c656e6c8a1d40 377 SMART SM00671 257 292 1.8E-7 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS12980 8470d000c31758242b8773b37ab23c19 108 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 105 5.9E-27 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CB4_RS11075 0bfae1df71799bd4a80e6a12decb60b2 477 Pfam PF00155 Aminotransferase class I and II 118 466 2.7E-37 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS11075 0bfae1df71799bd4a80e6a12decb60b2 477 Gene3D G3DSA:3.40.640.10 151 357 8.6E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS11075 0bfae1df71799bd4a80e6a12decb60b2 477 SUPERFAMILY SSF46785 6 80 1.58E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS11075 0bfae1df71799bd4a80e6a12decb60b2 477 SUPERFAMILY SSF53383 106 473 1.71E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS11075 0bfae1df71799bd4a80e6a12decb60b2 477 SMART SM00345 17 76 1.1E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS11075 0bfae1df71799bd4a80e6a12decb60b2 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 4.1E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS11075 0bfae1df71799bd4a80e6a12decb60b2 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 4.1E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS11075 0bfae1df71799bd4a80e6a12decb60b2 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 9.2E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS11075 0bfae1df71799bd4a80e6a12decb60b2 477 Gene3D G3DSA:1.10.10.10 2 78 2.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS11075 0bfae1df71799bd4a80e6a12decb60b2 477 Gene3D G3DSA:3.90.1150.10 358 474 7.9E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS13210 e460da4f54e84e10997cfc3d15a97177 230 Pfam PF08241 Methyltransferase domain 44 138 3.6E-29 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CB4_RS13210 e460da4f54e84e10997cfc3d15a97177 230 SUPERFAMILY SSF53335 3 181 1.44E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS13210 e460da4f54e84e10997cfc3d15a97177 230 Gene3D G3DSA:3.40.50.150 1 189 2.4E-37 T 29-03-2018 CB4_RS19870 f3a88ec74609c7fe46e79bc1dfc75cdc 349 SUPERFAMILY SSF56042 165 346 4.78E-54 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS19870 f3a88ec74609c7fe46e79bc1dfc75cdc 349 Gene3D G3DSA:3.90.650.10 165 347 6.5E-48 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS19870 f3a88ec74609c7fe46e79bc1dfc75cdc 349 Pfam PF00586 AIR synthase related protein, N-terminal domain 52 158 5.2E-21 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS19870 f3a88ec74609c7fe46e79bc1dfc75cdc 349 PIRSF PIRSF036407 1 349 4.8E-129 T 29-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CB4_RS19870 f3a88ec74609c7fe46e79bc1dfc75cdc 349 TIGRFAM TIGR00476 selD: selenide, water dikinase 8 317 6.7E-132 T 29-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CB4_RS19870 f3a88ec74609c7fe46e79bc1dfc75cdc 349 Pfam PF02769 AIR synthase related protein, C-terminal domain 170 346 2.7E-31 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS19870 f3a88ec74609c7fe46e79bc1dfc75cdc 349 SUPERFAMILY SSF55326 9 162 1.27E-42 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS19870 f3a88ec74609c7fe46e79bc1dfc75cdc 349 Gene3D G3DSA:3.30.1330.10 1 163 5.1E-36 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS19870 f3a88ec74609c7fe46e79bc1dfc75cdc 349 Hamap MF_00625 Selenide, water dikinase [selD]. 6 349 43.572 T 29-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CB4_RS02785 c91e8590f40fd6af03bca941f826e563 1084 SUPERFAMILY SSF52540 149 461 2.41E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02785 c91e8590f40fd6af03bca941f826e563 1084 Gene3D G3DSA:3.40.50.300 196 405 1.2E-28 T 29-03-2018 CB4_RS02785 c91e8590f40fd6af03bca941f826e563 1084 Pfam PF03308 ArgK protein 166 367 3.9E-42 T 29-03-2018 CB4_RS02785 c91e8590f40fd6af03bca941f826e563 1084 SUPERFAMILY SSF52242 4 143 1.44E-41 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CB4_RS02785 c91e8590f40fd6af03bca941f826e563 1084 Gene3D G3DSA:3.20.20.240 538 1080 8.3E-196 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CB4_RS02785 c91e8590f40fd6af03bca941f826e563 1084 Pfam PF02310 B12 binding domain 14 118 4.5E-14 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CB4_RS02785 c91e8590f40fd6af03bca941f826e563 1084 SUPERFAMILY SSF51703 504 1080 4.45E-153 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CB4_RS02785 c91e8590f40fd6af03bca941f826e563 1084 Pfam PF01642 Methylmalonyl-CoA mutase 561 1078 3.2E-141 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CB4_RS02785 c91e8590f40fd6af03bca941f826e563 1084 Gene3D G3DSA:3.40.50.280 8 161 5.2E-28 T 29-03-2018 CB4_RS02785 c91e8590f40fd6af03bca941f826e563 1084 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 11 1084 17.054 T 29-03-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 CB4_RS12230 dcc775b974508d2689d6aaa4e2800652 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 3.3E-24 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CB4_RS12230 dcc775b974508d2689d6aaa4e2800652 104 SUPERFAMILY SSF103481 5 102 8.11E-16 T 29-03-2018 CB4_RS13465 d60eced9c46edfef59f4a715480ebaa0 411 Pfam PF13641 Glycosyltransferase like family 2 43 270 3.9E-33 T 29-03-2018 CB4_RS13465 d60eced9c46edfef59f4a715480ebaa0 411 SUPERFAMILY SSF53448 35 315 3.82E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS13465 d60eced9c46edfef59f4a715480ebaa0 411 Gene3D G3DSA:3.90.550.10 32 303 4.5E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS14065 e7c03b4ad2db9f2c9b8cdbdbe448ca1f 247 PIRSF PIRSF004848 3 237 1.6E-77 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CB4_RS14065 e7c03b4ad2db9f2c9b8cdbdbe448ca1f 247 SUPERFAMILY SSF51419 6 229 1.96E-69 T 29-03-2018 IPR029066 PLP-binding barrel CB4_RS14065 e7c03b4ad2db9f2c9b8cdbdbe448ca1f 247 Pfam PF01168 Alanine racemase, N-terminal domain 13 231 3.4E-20 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS14065 e7c03b4ad2db9f2c9b8cdbdbe448ca1f 247 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 7 231 3.6E-60 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CB4_RS14065 e7c03b4ad2db9f2c9b8cdbdbe448ca1f 247 Gene3D G3DSA:3.20.20.10 2 237 2.7E-58 T 29-03-2018 IPR029066 PLP-binding barrel CB4_RS14065 e7c03b4ad2db9f2c9b8cdbdbe448ca1f 247 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 78 92 - T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 3.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 3.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 3.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 3.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 Gene3D G3DSA:3.30.450.20 96 247 0.0037 T 29-03-2018 CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 SMART SM00387 355 466 3.5E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 SMART SM00388 243 310 2.6E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 Gene3D G3DSA:3.30.565.10 317 466 1.8E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 463 1.2E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 SUPERFAMILY SSF55874 299 463 1.83E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 SUPERFAMILY SSF47384 226 310 5.69E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 SMART SM00304 189 242 1.3E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 Gene3D G3DSA:1.10.287.130 248 306 7.3E-17 T 29-03-2018 CB4_RS06220 a88b891bbf660937a1d529c69edf3424 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 310 3.5E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS05080 4748ad570fe8434f869dd6cfb60fc427 441 Pfam PF14535 AMP-binding enzyme C-terminal domain 335 436 9.0E-25 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal CB4_RS05080 4748ad570fe8434f869dd6cfb60fc427 441 PIRSF PIRSF006444 1 438 3.0E-198 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CB4_RS05080 4748ad570fe8434f869dd6cfb60fc427 441 Pfam PF00501 AMP-binding enzyme 77 334 5.0E-15 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS05080 4748ad570fe8434f869dd6cfb60fc427 441 Gene3D G3DSA:3.40.50.980 76 247 9.3E-18 T 29-03-2018 CB4_RS05080 4748ad570fe8434f869dd6cfb60fc427 441 Gene3D G3DSA:3.30.300.30 325 439 7.7E-8 T 29-03-2018 CB4_RS05080 4748ad570fe8434f869dd6cfb60fc427 441 SUPERFAMILY SSF56801 21 377 2.22E-60 T 29-03-2018 CB4_RS19250 061148a53a512a5754804370064a219a 582 Gene3D G3DSA:1.20.1560.10 1 328 7.9E-69 T 29-03-2018 CB4_RS19250 061148a53a512a5754804370064a219a 582 Gene3D G3DSA:3.40.50.300 329 582 1.6E-77 T 29-03-2018 CB4_RS19250 061148a53a512a5754804370064a219a 582 SMART SM00382 367 559 1.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS19250 061148a53a512a5754804370064a219a 582 Pfam PF00664 ABC transporter transmembrane region 23 289 7.4E-43 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS19250 061148a53a512a5754804370064a219a 582 Pfam PF00005 ABC transporter 358 507 2.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS19250 061148a53a512a5754804370064a219a 582 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS19250 061148a53a512a5754804370064a219a 582 SUPERFAMILY SSF90123 5 327 4.05E-77 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS19250 061148a53a512a5754804370064a219a 582 SUPERFAMILY SSF52540 330 577 7.03E-96 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03090 f3487d928474cea339213b036a0a392d 338 SUPERFAMILY SSF53067 142 326 6.48E-48 T 29-03-2018 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 3.4E-57 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 3.4E-57 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 3.4E-57 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 3.4E-57 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 3.4E-57 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 Gene3D G3DSA:3.30.420.40 245 309 1.3E-8 T 29-03-2018 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 4 326 1.3E-131 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 Gene3D G3DSA:3.90.640.10 189 244 2.1E-27 T 29-03-2018 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 Gene3D G3DSA:3.30.420.40 152 188 0.0013 T 29-03-2018 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 Pfam PF06723 MreB/Mbl protein 4 326 6.6E-144 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 SUPERFAMILY SSF53067 3 140 4.09E-37 T 29-03-2018 CB4_RS03090 f3487d928474cea339213b036a0a392d 338 Gene3D G3DSA:3.30.420.40 2 151 1.1E-34 T 29-03-2018 CB4_RS17840 df9ff7f227f81eda961ab5283643efcb 255 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 248 2.7E-110 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CB4_RS17840 df9ff7f227f81eda961ab5283643efcb 255 Gene3D G3DSA:3.20.20.70 1 255 6.6E-54 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS17840 df9ff7f227f81eda961ab5283643efcb 255 SUPERFAMILY SSF110399 1 240 2.75E-81 T 29-03-2018 CB4_RS17840 df9ff7f227f81eda961ab5283643efcb 255 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 42.651 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CB4_RS02330 f10c539ad6e372f8dd2a35a2a8d8d9e5 234 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 210 232 3.6E-6 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CB4_RS02330 f10c539ad6e372f8dd2a35a2a8d8d9e5 234 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS02330 f10c539ad6e372f8dd2a35a2a8d8d9e5 234 PIRSF PIRSF039137 1 234 1.8E-107 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CB4_RS02330 f10c539ad6e372f8dd2a35a2a8d8d9e5 234 SMART SM00382 26 227 1.4E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS02330 f10c539ad6e372f8dd2a35a2a8d8d9e5 234 SUPERFAMILY SSF52540 2 231 3.48E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02330 f10c539ad6e372f8dd2a35a2a8d8d9e5 234 Gene3D G3DSA:3.40.50.300 1 234 2.6E-61 T 29-03-2018 CB4_RS02330 f10c539ad6e372f8dd2a35a2a8d8d9e5 234 Pfam PF00005 ABC transporter 17 161 1.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS07970 a48d6f031b683ca9842510cc194d22f4 454 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 446 29.995 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CB4_RS07970 a48d6f031b683ca9842510cc194d22f4 454 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 9 359 2.2E-141 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CB4_RS07970 a48d6f031b683ca9842510cc194d22f4 454 Pfam PF02601 Exonuclease VII, large subunit 126 443 2.9E-100 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CB4_RS07970 a48d6f031b683ca9842510cc194d22f4 454 Pfam PF13742 OB-fold nucleic acid binding domain 8 103 1.7E-29 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CB4_RS07970 a48d6f031b683ca9842510cc194d22f4 454 Gene3D G3DSA:2.40.50.140 1 104 5.5E-8 T 29-03-2018 CB4_RS07555 ba5ae19fcdf5396a9a342b7d088ade02 529 Gene3D G3DSA:3.30.300.30 421 527 1.1E-27 T 29-03-2018 CB4_RS07555 ba5ae19fcdf5396a9a342b7d088ade02 529 Gene3D G3DSA:3.40.50.980 5 175 1.5E-45 T 29-03-2018 CB4_RS07555 ba5ae19fcdf5396a9a342b7d088ade02 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS07555 ba5ae19fcdf5396a9a342b7d088ade02 529 Gene3D G3DSA:3.40.50.980 176 334 3.2E-42 T 29-03-2018 CB4_RS07555 ba5ae19fcdf5396a9a342b7d088ade02 529 Pfam PF00501 AMP-binding enzyme 12 427 1.2E-101 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS07555 ba5ae19fcdf5396a9a342b7d088ade02 529 SUPERFAMILY SSF56801 5 523 2.35E-153 T 29-03-2018 CB4_RS07555 ba5ae19fcdf5396a9a342b7d088ade02 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 511 2.2E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS07555 ba5ae19fcdf5396a9a342b7d088ade02 529 Gene3D G3DSA:2.30.38.10 344 420 5.8E-21 T 29-03-2018 CB4_RS05295 3e790fe6725206d3cdb2a5ad88fd14e0 195 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 191 3.4E-79 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CB4_RS05295 3e790fe6725206d3cdb2a5ad88fd14e0 195 SUPERFAMILY SSF53271 1 186 2.97E-42 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CB4_RS05295 3e790fe6725206d3cdb2a5ad88fd14e0 195 Gene3D G3DSA:3.40.50.2020 3 188 2.7E-21 T 29-03-2018 CB4_RS05295 3e790fe6725206d3cdb2a5ad88fd14e0 195 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 41.172 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CB4_RS05295 3e790fe6725206d3cdb2a5ad88fd14e0 195 Pfam PF00156 Phosphoribosyl transferase domain 38 156 2.2E-6 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CB4_RS11120 9d7b1614c5fc41382fa71bf6c11d852c 562 Gene3D G3DSA:3.30.450.90 152 285 2.8E-43 T 29-03-2018 CB4_RS11120 9d7b1614c5fc41382fa71bf6c11d852c 562 SUPERFAMILY SSF160246 9 145 1.03E-29 T 29-03-2018 CB4_RS11120 9d7b1614c5fc41382fa71bf6c11d852c 562 Gene3D G3DSA:3.40.50.300 286 562 1.6E-59 T 29-03-2018 CB4_RS11120 9d7b1614c5fc41382fa71bf6c11d852c 562 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 49 147 1.6E-17 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 CB4_RS11120 9d7b1614c5fc41382fa71bf6c11d852c 562 Pfam PF00437 Type II/IV secretion system protein 190 452 2.1E-81 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CB4_RS11120 9d7b1614c5fc41382fa71bf6c11d852c 562 SMART SM00382 313 455 1.8E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS11120 9d7b1614c5fc41382fa71bf6c11d852c 562 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 380 394 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CB4_RS11120 9d7b1614c5fc41382fa71bf6c11d852c 562 SUPERFAMILY SSF52540 168 561 6.81E-97 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 8 468 1.2E-232 T 29-03-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 SUPERFAMILY SSF48557 6 462 4.87E-148 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 PRINTS PR00145 Argininosuccinate lyase family signature 177 197 1.0E-7 T 29-03-2018 CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 PRINTS PR00145 Argininosuccinate lyase family signature 136 158 1.0E-7 T 29-03-2018 CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 PRINTS PR00145 Argininosuccinate lyase family signature 319 335 1.0E-7 T 29-03-2018 CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 Gene3D G3DSA:1.10.275.10 5 140 2.9E-52 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 Gene3D G3DSA:1.20.200.10 141 417 5.8E-82 T 29-03-2018 CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 Pfam PF00206 Lyase 15 344 3.5E-111 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 Gene3D G3DSA:1.10.40.30 418 467 1.6E-19 T 29-03-2018 CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 2.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 2.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 2.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 2.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CB4_RS06405 8f8c5f1a337b9f37d5606810cc9a9d65 475 Pfam PF10415 Fumarase C C-terminus 411 463 1.2E-18 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS00835 25bd4334392f75eb574dc10510c2528a 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.483 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00835 25bd4334392f75eb574dc10510c2528a 37 SUPERFAMILY SSF57840 2 37 1.83E-16 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00835 25bd4334392f75eb574dc10510c2528a 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 3.0E-8 T 29-03-2018 CB4_RS00835 25bd4334392f75eb574dc10510c2528a 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00835 25bd4334392f75eb574dc10510c2528a 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 1.6E-22 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00835 25bd4334392f75eb574dc10510c2528a 37 Pfam PF00444 Ribosomal protein L36 2 37 1.7E-18 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 SUPERFAMILY SSF53067 1 158 3.72E-63 T 29-03-2018 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 Pfam PF00012 Hsp70 protein 80 573 1.8E-221 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 Pfam PF00012 Hsp70 protein 4 78 8.1E-32 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 Gene3D G3DSA:2.60.34.10 360 501 2.4E-67 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 1.2E-287 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 SUPERFAMILY SSF53067 160 352 2.41E-66 T 29-03-2018 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 Gene3D G3DSA:3.30.420.40 171 336 1.2E-48 T 29-03-2018 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 SUPERFAMILY SSF100920 354 510 6.8E-64 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 Gene3D G3DSA:1.20.1270.10 502 588 2.5E-20 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 Gene3D G3DSA:3.30.420.40 1 170 1.4E-73 T 29-03-2018 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 SUPERFAMILY SSF100934 477 580 6.02E-15 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 PRINTS PR00301 70kDa heat shock protein signature 53 61 3.5E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 PRINTS PR00301 70kDa heat shock protein signature 172 182 3.5E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 PRINTS PR00301 70kDa heat shock protein signature 304 320 3.5E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 PRINTS PR00301 70kDa heat shock protein signature 439 455 3.5E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.5E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 PRINTS PR00301 70kDa heat shock protein signature 335 355 3.5E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 PRINTS PR00301 70kDa heat shock protein signature 113 133 3.5E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 PRINTS PR00301 70kDa heat shock protein signature 358 377 3.5E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 PRINTS PR00301 70kDa heat shock protein signature 31 43 3.5E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CB4_RS06685 e0ee619200eaa76ea5d3bb72f9e689ef 610 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 604 37.384 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CB4_RS05765 c2fe93b5b413beb12131d3c7ae54ce46 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 366 380 2.0E-19 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS05765 c2fe93b5b413beb12131d3c7ae54ce46 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 64 76 2.0E-19 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS05765 c2fe93b5b413beb12131d3c7ae54ce46 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 163 191 2.0E-19 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS05765 c2fe93b5b413beb12131d3c7ae54ce46 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 382 401 2.0E-19 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS05765 c2fe93b5b413beb12131d3c7ae54ce46 404 Gene3D G3DSA:3.30.70.1120 80 166 0.065 T 29-03-2018 CB4_RS05765 c2fe93b5b413beb12131d3c7ae54ce46 404 Gene3D G3DSA:3.30.70.1120 309 371 0.38 T 29-03-2018 CB4_RS05765 c2fe93b5b413beb12131d3c7ae54ce46 404 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 163 191 - T 29-03-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 CB4_RS05765 c2fe93b5b413beb12131d3c7ae54ce46 404 Pfam PF00482 Type II secretion system (T2SS), protein F 68 191 1.6E-26 T 29-03-2018 IPR018076 Type II secretion system F domain CB4_RS05765 c2fe93b5b413beb12131d3c7ae54ce46 404 Pfam PF00482 Type II secretion system (T2SS), protein F 272 393 5.5E-30 T 29-03-2018 IPR018076 Type II secretion system F domain CB4_RS17455 6515bd1109c83eb8b55dfd44a48ba36b 86 PIRSF PIRSF010606 1 86 2.5E-35 T 29-03-2018 IPR016571 Spore coat assembly protein CotJB CB4_RS17455 6515bd1109c83eb8b55dfd44a48ba36b 86 Pfam PF12652 CotJB protein 10 85 5.3E-27 T 29-03-2018 IPR024207 Spore coat assembly protein CotJB, domain CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 SMART SM00490 429 506 1.3E-8 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 462 480 1.1E-16 T 29-03-2018 CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 3 23 1.1E-16 T 29-03-2018 CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 481 506 1.1E-16 T 29-03-2018 CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 416 438 1.1E-16 T 29-03-2018 CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 Gene3D G3DSA:3.40.50.300 174 360 1.1E-25 T 29-03-2018 CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 Gene3D G3DSA:3.40.50.300 384 521 3.9E-17 T 29-03-2018 CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 SUPERFAMILY SSF52540 399 517 1.5E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 SUPERFAMILY SSF52540 296 366 1.5E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 SUPERFAMILY SSF52540 126 351 8.12E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 SMART SM00487 177 354 1.1E-19 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 Pfam PF13625 Helicase conserved C-terminal domain 5 130 3.3E-37 T 29-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 358 543 1.1E-49 T 29-03-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CB4_RS15330 a2b5341cfdfcd534f78a7d6ba749497e 551 Pfam PF04851 Type III restriction enzyme, res subunit 178 332 3.2E-12 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CB4_RS17450 741b8014ed8c87fb115da7cd4f9e8905 76 Pfam PF11007 Spore coat associated protein JA (CotJA) 28 63 1.7E-10 T 29-03-2018 IPR020256 Spore coat protein CotJA CB4_RS17450 741b8014ed8c87fb115da7cd4f9e8905 76 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 6 71 1.0E-15 T 29-03-2018 IPR020256 Spore coat protein CotJA CB4_RS02700 f46a5a12ffc9bfa9ddce99eaca42602d 307 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 132 146 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS02700 f46a5a12ffc9bfa9ddce99eaca42602d 307 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 304 1.0E-70 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS02700 f46a5a12ffc9bfa9ddce99eaca42602d 307 Gene3D G3DSA:3.10.290.10 1 72 1.7E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS02700 f46a5a12ffc9bfa9ddce99eaca42602d 307 Gene3D G3DSA:3.30.2350.10 80 307 1.5E-64 T 29-03-2018 CB4_RS02700 f46a5a12ffc9bfa9ddce99eaca42602d 307 SUPERFAMILY SSF55120 74 305 8.48E-68 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS02700 f46a5a12ffc9bfa9ddce99eaca42602d 307 Pfam PF00849 RNA pseudouridylate synthase 90 250 5.9E-31 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS15085 6085381418381b971c5674556ae09d64 431 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 425 2.5E-135 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CB4_RS15085 6085381418381b971c5674556ae09d64 431 ProSitePatterns PS00885 EPSP synthase signature 2. 339 357 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CB4_RS15085 6085381418381b971c5674556ae09d64 431 Gene3D G3DSA:3.65.10.10 217 428 1.5E-53 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS15085 6085381418381b971c5674556ae09d64 431 Gene3D G3DSA:3.65.10.10 19 216 1.6E-53 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS15085 6085381418381b971c5674556ae09d64 431 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 420 7.4E-126 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS15085 6085381418381b971c5674556ae09d64 431 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CB4_RS15085 6085381418381b971c5674556ae09d64 431 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 428 34.618 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CB4_RS15085 6085381418381b971c5674556ae09d64 431 SUPERFAMILY SSF55205 4 424 2.94E-137 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CB4_RS15085 6085381418381b971c5674556ae09d64 431 PIRSF PIRSF000505 1 428 1.5E-119 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CB4_RS08605 39722d352907116dc9041c6c9340af33 334 Gene3D G3DSA:3.40.718.10 1 330 8.4E-107 T 29-03-2018 CB4_RS08605 39722d352907116dc9041c6c9340af33 334 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 333 143.244 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CB4_RS08605 39722d352907116dc9041c6c9340af33 334 PIRSF PIRSF002465 1 332 4.0E-126 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CB4_RS08605 39722d352907116dc9041c6c9340af33 334 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 2 327 2.9E-123 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CB4_RS08605 39722d352907116dc9041c6c9340af33 334 SUPERFAMILY SSF53659 1 327 2.3E-101 T 29-03-2018 CB4_RS08605 39722d352907116dc9041c6c9340af33 334 Pfam PF02504 Fatty acid synthesis protein 1 318 7.7E-117 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CB4_RS03015 a122b7da06886cc2a1591dce8e19b71e 333 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 13 333 25.167 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03015 a122b7da06886cc2a1591dce8e19b71e 333 Pfam PF00146 NADH dehydrogenase 22 327 5.8E-124 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03015 a122b7da06886cc2a1591dce8e19b71e 333 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 216 229 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03885 b5962720704caf03b8de6fa29dbb96cf 76 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 6.5E-15 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CB4_RS03885 b5962720704caf03b8de6fa29dbb96cf 76 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 6.5E-15 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CB4_RS03885 b5962720704caf03b8de6fa29dbb96cf 76 PRINTS PR01651 Protein-export SecG membrane protein signature 55 76 6.5E-15 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CB4_RS03885 b5962720704caf03b8de6fa29dbb96cf 76 ProDom PD350688 MEMBRANE SECG PROTEIN-EXPORT TRANSMEMBRANE PROBABLE TRANSLOCATION UNIQUE PREDICTED 8 67 0.002 T 29-03-2018 CB4_RS03885 b5962720704caf03b8de6fa29dbb96cf 76 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 4 74 2.6E-22 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CB4_RS03885 b5962720704caf03b8de6fa29dbb96cf 76 Pfam PF03840 Preprotein translocase SecG subunit 5 74 3.0E-22 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 SUPERFAMILY SSF64496 162 191 1.07E-7 T 29-03-2018 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 TIGRFAM TIGR01453 grpIintron_endo: group I intron endonuclease 3 190 4.8E-24 T 29-03-2018 IPR006350 Intron endonuclease, group I GO:0004519 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 SUPERFAMILY SSF82771 2 98 2.48E-16 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 SMART SM00465 1 100 3.8E-8 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 Gene3D G3DSA:1.10.10.10 225 283 1.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 Pfam PF07460 NUMOD3 motif (2 copies) 209 234 0.38 T 29-03-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 Pfam PF07460 NUMOD3 motif (2 copies) 139 156 0.0055 T 29-03-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 Pfam PF07460 NUMOD3 motif (2 copies) 176 212 4.8E-12 T 29-03-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 Pfam PF07460 NUMOD3 motif (2 copies) 163 185 9.6E-7 T 29-03-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 Pfam PF01541 GIY-YIG catalytic domain 2 88 5.8E-9 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 Gene3D G3DSA:3.40.1440.10 1 102 1.2E-14 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 SUPERFAMILY SSF64496 192 275 1.57E-13 T 29-03-2018 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 SMART SM00496 172 188 0.0015 T 29-03-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 SMART SM00496 200 216 0.059 T 29-03-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 SMART SM00496 146 162 410.0 T 29-03-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 CB4_RS09780 9b0425dfba43a9fd8a130332395441f3 284 SMART SM00496 221 237 55.0 T 29-03-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 Gene3D G3DSA:3.40.50.1000 442 570 1.4E-34 T 29-03-2018 IPR023214 HAD-like domain CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 537 549 1.2E-25 T 29-03-2018 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 514 533 1.2E-25 T 29-03-2018 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 439 450 1.2E-25 T 29-03-2018 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 152 166 1.2E-25 T 29-03-2018 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 303 317 1.2E-25 T 29-03-2018 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 461 471 1.2E-25 T 29-03-2018 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 Pfam PF00122 E1-E2 ATPase 106 280 2.5E-34 T 29-03-2018 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 SUPERFAMILY SSF81665 31 104 1.57E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 SUPERFAMILY SSF81665 206 297 1.57E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 6 674 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 73 342 8.8E-34 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 369 598 1.2E-45 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 SUPERFAMILY SSF81653 109 205 2.48E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 Gene3D G3DSA:2.70.150.10 5 206 2.7E-27 T 29-03-2018 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 305 311 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 SUPERFAMILY SSF56784 291 315 5.43E-40 T 29-03-2018 IPR023214 HAD-like domain CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 SUPERFAMILY SSF56784 350 402 5.43E-40 T 29-03-2018 IPR023214 HAD-like domain CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 SUPERFAMILY SSF56784 433 557 5.43E-40 T 29-03-2018 IPR023214 HAD-like domain CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 Gene3D G3DSA:3.40.1110.10 314 441 2.4E-20 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 8 678 40.443 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CB4_RS04835 37f3fee884968a1cfaea525c66f9894d 678 Pfam PF00702 haloacid dehalogenase-like hydrolase 299 528 3.7E-38 T 29-03-2018 CB4_RS03425 669d8620e93678c8baa92fbfb572a474 90 SUPERFAMILY SSF117130 1 55 2.22E-20 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CB4_RS03425 669d8620e93678c8baa92fbfb572a474 90 Hamap MF_00167 Carbon storage regulator [csrA]. 1 68 20.985 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CB4_RS03425 669d8620e93678c8baa92fbfb572a474 90 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 58 3.8E-28 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CB4_RS03425 669d8620e93678c8baa92fbfb572a474 90 Pfam PF02599 Global regulator protein family 1 53 7.0E-26 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CB4_RS03425 669d8620e93678c8baa92fbfb572a474 90 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 4.0E-13 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CB4_RS10050 f635f6fe0b21f20da8529bf597f25cb8 552 Gene3D G3DSA:3.30.470.20 391 528 5.9E-10 T 29-03-2018 CB4_RS10050 f635f6fe0b21f20da8529bf597f25cb8 552 SUPERFAMILY SSF56059 312 514 9.06E-13 T 29-03-2018 CB4_RS10050 f635f6fe0b21f20da8529bf597f25cb8 552 Gene3D G3DSA:3.30.1490.20 318 390 4.6E-9 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS10050 f635f6fe0b21f20da8529bf597f25cb8 552 Pfam PF14398 YheC/D like ATP-grasp 290 545 1.7E-65 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CB4_RS01945 dc7a9118b1564757102d0c55683276f6 238 Pfam PF02527 rRNA small subunit methyltransferase G 21 205 2.0E-58 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CB4_RS01945 dc7a9118b1564757102d0c55683276f6 238 SUPERFAMILY SSF53335 6 237 1.31E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS01945 dc7a9118b1564757102d0c55683276f6 238 Gene3D G3DSA:3.40.50.150 4 238 2.0E-38 T 29-03-2018 CB4_RS01945 dc7a9118b1564757102d0c55683276f6 238 PIRSF PIRSF003078 1 220 2.6E-61 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CB4_RS01945 dc7a9118b1564757102d0c55683276f6 238 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 214 2.9E-55 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CB4_RS01945 dc7a9118b1564757102d0c55683276f6 238 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 29.635 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CB4_RS02200 97986f3cd5b2f0d2dcca09aa3987abab 293 SUPERFAMILY SSF53850 90 292 5.55E-46 T 29-03-2018 CB4_RS02200 97986f3cd5b2f0d2dcca09aa3987abab 293 SUPERFAMILY SSF46785 1 84 6.86E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02200 97986f3cd5b2f0d2dcca09aa3987abab 293 Gene3D G3DSA:3.40.190.10 177 264 4.4E-24 T 29-03-2018 CB4_RS02200 97986f3cd5b2f0d2dcca09aa3987abab 293 Gene3D G3DSA:1.10.10.10 1 83 1.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02200 97986f3cd5b2f0d2dcca09aa3987abab 293 Gene3D G3DSA:3.40.190.10 88 176 1.0E-22 T 29-03-2018 CB4_RS02200 97986f3cd5b2f0d2dcca09aa3987abab 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.9E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS02200 97986f3cd5b2f0d2dcca09aa3987abab 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS02200 97986f3cd5b2f0d2dcca09aa3987abab 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS02200 97986f3cd5b2f0d2dcca09aa3987abab 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS02200 97986f3cd5b2f0d2dcca09aa3987abab 293 Pfam PF03466 LysR substrate binding domain 90 290 1.2E-50 T 29-03-2018 IPR005119 LysR, substrate-binding CB4_RS06540 83ad25de23e47e783507f7396ed03e59 97 SMART SM01103 2 85 1.1E-44 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CB4_RS06540 83ad25de23e47e783507f7396ed03e59 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 4.0E-32 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CB4_RS06540 83ad25de23e47e783507f7396ed03e59 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 1.7E-23 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CB4_RS06540 83ad25de23e47e783507f7396ed03e59 97 SUPERFAMILY SSF75471 2 94 2.88E-32 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CB4_RS06540 83ad25de23e47e783507f7396ed03e59 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 97 1.8E-41 T 29-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 CB4_RS06540 83ad25de23e47e783507f7396ed03e59 97 Gene3D G3DSA:3.30.110.60 1 97 5.8E-30 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CB4_RS11165 f06b334ba334fc6e202779ccbdb95fa8 633 SUPERFAMILY SSF51735 285 548 2.96E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS11165 f06b334ba334fc6e202779ccbdb95fa8 633 Pfam PF02719 Polysaccharide biosynthesis protein 287 570 4.9E-121 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CB4_RS11165 f06b334ba334fc6e202779ccbdb95fa8 633 Pfam PF13727 CoA-binding domain 70 240 1.4E-14 T 29-03-2018 CB4_RS11165 f06b334ba334fc6e202779ccbdb95fa8 633 Gene3D G3DSA:3.40.50.720 141 268 2.5E-25 T 29-03-2018 CB4_RS11165 f06b334ba334fc6e202779ccbdb95fa8 633 SUPERFAMILY SSF53335 106 311 6.81E-17 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS11165 f06b334ba334fc6e202779ccbdb95fa8 633 Gene3D G3DSA:3.40.50.720 281 605 1.8E-64 T 29-03-2018 CB4_RS09080 86fbd0877fdabb5c8073ba82dd8cebc3 153 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 100 149 3.2E-12 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CB4_RS09080 86fbd0877fdabb5c8073ba82dd8cebc3 153 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 7 152 2.9E-45 T 29-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 CB4_RS09080 86fbd0877fdabb5c8073ba82dd8cebc3 153 Pfam PF00460 Flagella basal body rod protein 7 35 7.4E-9 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CB4_RS16885 48d848d4ce560821d75865d8fdc8d3f9 351 SUPERFAMILY SSF53822 60 266 7.07E-16 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS16885 48d848d4ce560821d75865d8fdc8d3f9 351 Gene3D G3DSA:3.40.50.2300 171 307 1.9E-17 T 29-03-2018 CB4_RS16885 48d848d4ce560821d75865d8fdc8d3f9 351 Pfam PF04392 ABC transporter substrate binding protein 46 331 1.1E-91 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein CB4_RS16885 48d848d4ce560821d75865d8fdc8d3f9 351 Gene3D G3DSA:3.40.50.2300 43 170 6.7E-23 T 29-03-2018 CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 Pfam PF00563 EAL domain 189 420 2.7E-53 T 29-03-2018 IPR001633 EAL domain CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 Pfam PF00571 CBS domain 454 507 2.4E-4 T 29-03-2018 IPR000644 CBS domain CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 Pfam PF00571 CBS domain 521 579 3.3E-5 T 29-03-2018 IPR000644 CBS domain CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 SMART SM00267 576 749 4.5E-14 T 29-03-2018 IPR000160 GGDEF domain CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 Gene3D G3DSA:3.10.580.10 437 584 2.1E-13 T 29-03-2018 CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 SUPERFAMILY SSF55073 592 745 2.04E-20 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 SUPERFAMILY SSF54631 448 580 1.64E-12 T 29-03-2018 CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 Gene3D G3DSA:3.30.70.270 27 192 5.4E-7 T 29-03-2018 CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 Pfam PF00990 Diguanylate cyclase, GGDEF domain 591 741 1.5E-16 T 29-03-2018 IPR000160 GGDEF domain CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 SMART SM00116 528 579 19.0 T 29-03-2018 IPR000644 CBS domain CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 SMART SM00116 460 508 0.29 T 29-03-2018 IPR000644 CBS domain CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 SUPERFAMILY SSF141868 189 421 2.48E-64 T 29-03-2018 IPR001633 EAL domain CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 583 740 1.1E-14 T 29-03-2018 IPR000160 GGDEF domain CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 Gene3D G3DSA:3.20.20.450 193 434 5.9E-67 T 29-03-2018 IPR001633 EAL domain CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 Gene3D G3DSA:3.30.70.270 585 750 5.5E-24 T 29-03-2018 CB4_RS18245 ad3fe24dc9207c6845770c2765583e0f 759 SMART SM00052 183 425 7.4E-48 T 29-03-2018 IPR001633 EAL domain CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 60.576 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 Gene3D G3DSA:3.30.930.10 1 204 4.1E-86 T 29-03-2018 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 SUPERFAMILY SSF55681 1 280 1.49E-136 T 29-03-2018 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 279 2.2E-154 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 Gene3D G3DSA:1.20.58.180 206 282 9.1E-37 T 29-03-2018 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 289 5.0E-167 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 2.5E-69 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 2.5E-69 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 2.5E-69 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 2.5E-69 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 2.5E-69 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07130 3ab4e6333d4980369e52fa0adb697a2f 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 2.5E-69 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS10235 b40652c5420839aeca5be473ef876a4b 69 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 2 68 5.5E-28 T 29-03-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like CB4_RS10235 b40652c5420839aeca5be473ef876a4b 69 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 69 26.214 T 29-03-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like CB4_RS06535 074826f6de7ceb6d693a2d3f3108821c 285 Gene3D G3DSA:3.40.50.10860 1 114 1.8E-45 T 29-03-2018 CB4_RS06535 074826f6de7ceb6d693a2d3f3108821c 285 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 8 281 1.1E-81 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CB4_RS06535 074826f6de7ceb6d693a2d3f3108821c 285 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 120 195 1.4E-8 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CB4_RS06535 074826f6de7ceb6d693a2d3f3108821c 285 SUPERFAMILY SSF51735 105 281 1.9E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS06535 074826f6de7ceb6d693a2d3f3108821c 285 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 5 279 35.563 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CB4_RS06535 074826f6de7ceb6d693a2d3f3108821c 285 Gene3D G3DSA:3.40.50.720 115 284 7.6E-33 T 29-03-2018 CB4_RS06535 074826f6de7ceb6d693a2d3f3108821c 285 SUPERFAMILY SSF53223 3 104 9.21E-37 T 29-03-2018 CB4_RS06535 074826f6de7ceb6d693a2d3f3108821c 285 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 92 8.5E-31 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CB4_RS06485 7a7686f39388e801756f04476d184543 240 Gene3D G3DSA:3.40.50.1820 2 240 4.3E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS06485 7a7686f39388e801756f04476d184543 240 SUPERFAMILY SSF53474 9 236 1.18E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS06485 7a7686f39388e801756f04476d184543 240 Pfam PF00756 Putative esterase 17 232 4.1E-34 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CB4_RS05475 74b251a61a5b337b70ad9ed02780f2af 194 SUPERFAMILY SSF46689 3 82 4.09E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS05475 74b251a61a5b337b70ad9ed02780f2af 194 Pfam PF08359 YsiA-like protein, C-terminal region 59 191 1.4E-46 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal CB4_RS05475 74b251a61a5b337b70ad9ed02780f2af 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS05475 74b251a61a5b337b70ad9ed02780f2af 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS05475 74b251a61a5b337b70ad9ed02780f2af 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 1.1E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS05475 74b251a61a5b337b70ad9ed02780f2af 194 SUPERFAMILY SSF48498 81 193 1.02E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS05475 74b251a61a5b337b70ad9ed02780f2af 194 Gene3D G3DSA:1.10.357.10 57 193 1.5E-14 T 29-03-2018 CB4_RS05475 74b251a61a5b337b70ad9ed02780f2af 194 Gene3D G3DSA:1.10.10.60 2 56 7.1E-15 T 29-03-2018 CB4_RS16875 4e64f88742861ed8bd13ce21bfa5abc3 264 SMART SM00382 31 235 8.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS16875 4e64f88742861ed8bd13ce21bfa5abc3 264 Pfam PF00005 ABC transporter 22 177 1.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS16875 4e64f88742861ed8bd13ce21bfa5abc3 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS16875 4e64f88742861ed8bd13ce21bfa5abc3 264 Gene3D G3DSA:3.40.50.300 1 260 1.6E-53 T 29-03-2018 CB4_RS16875 4e64f88742861ed8bd13ce21bfa5abc3 264 SUPERFAMILY SSF52540 2 236 2.25E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00785 e1be518fbe6b022888443c22ebd6a77f 283 Gene3D G3DSA:1.10.287.950 61 282 2.2E-35 T 29-03-2018 CB4_RS00785 e1be518fbe6b022888443c22ebd6a77f 283 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 135 279 5.3E-29 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS00785 e1be518fbe6b022888443c22ebd6a77f 283 SUPERFAMILY SSF58104 118 279 2.22E-40 T 29-03-2018 CB4_RS00785 e1be518fbe6b022888443c22ebd6a77f 283 SMART SM00283 78 282 2.9E-12 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS10060 55b5f4e3b773c2dee87d9f967ba141fd 494 Pfam PF02875 Mur ligase family, glutamate ligase domain 351 427 2.8E-11 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS10060 55b5f4e3b773c2dee87d9f967ba141fd 494 SUPERFAMILY SSF53623 133 344 6.41E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS10060 55b5f4e3b773c2dee87d9f967ba141fd 494 SUPERFAMILY SSF53244 348 474 1.03E-19 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS10060 55b5f4e3b773c2dee87d9f967ba141fd 494 Pfam PF08245 Mur ligase middle domain 139 325 2.2E-42 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS10060 55b5f4e3b773c2dee87d9f967ba141fd 494 Gene3D G3DSA:3.40.1190.10 115 342 8.3E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS10060 55b5f4e3b773c2dee87d9f967ba141fd 494 Gene3D G3DSA:3.90.190.20 346 492 4.4E-26 T 29-03-2018 CB4_RS18910 843062c1481477c86fca862809d870c3 245 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 205 6.2E-11 T 29-03-2018 IPR023214 HAD-like domain CB4_RS18910 843062c1481477c86fca862809d870c3 245 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 29-03-2018 CB4_RS18910 843062c1481477c86fca862809d870c3 245 Gene3D G3DSA:3.40.50.1000 1 225 9.2E-24 T 29-03-2018 IPR023214 HAD-like domain CB4_RS18910 843062c1481477c86fca862809d870c3 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 195 208 2.0E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS18910 843062c1481477c86fca862809d870c3 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 2.0E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS18910 843062c1481477c86fca862809d870c3 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 166 2.0E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS18910 843062c1481477c86fca862809d870c3 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 116 129 2.0E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS18910 843062c1481477c86fca862809d870c3 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 168 188 2.0E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS18910 843062c1481477c86fca862809d870c3 245 SUPERFAMILY SSF56784 5 209 3.41E-27 T 29-03-2018 IPR023214 HAD-like domain CB4_RS17385 7b54a861abc1a1cb14deae830582a48b 237 PRINTS PR00834 HtrA/DegQ protease family signature 103 123 1.4E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS17385 7b54a861abc1a1cb14deae830582a48b 237 PRINTS PR00834 HtrA/DegQ protease family signature 202 219 1.4E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS17385 7b54a861abc1a1cb14deae830582a48b 237 PRINTS PR00834 HtrA/DegQ protease family signature 82 94 1.4E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS17385 7b54a861abc1a1cb14deae830582a48b 237 PRINTS PR00834 HtrA/DegQ protease family signature 144 168 1.4E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS17385 7b54a861abc1a1cb14deae830582a48b 237 PRINTS PR00834 HtrA/DegQ protease family signature 180 197 1.4E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS17385 7b54a861abc1a1cb14deae830582a48b 237 Gene3D G3DSA:2.40.10.10 141 235 4.8E-36 T 29-03-2018 CB4_RS17385 7b54a861abc1a1cb14deae830582a48b 237 Pfam PF13365 Trypsin-like peptidase domain 73 209 1.1E-30 T 29-03-2018 CB4_RS17385 7b54a861abc1a1cb14deae830582a48b 237 SUPERFAMILY SSF50494 21 236 4.18E-57 T 29-03-2018 IPR009003 Peptidase S1, PA clan CB4_RS17385 7b54a861abc1a1cb14deae830582a48b 237 Gene3D G3DSA:2.40.10.10 19 140 3.3E-30 T 29-03-2018 CB4_RS18440 6c789adb3a98bba1d218af71c6432e31 1142 Gene3D G3DSA:3.20.20.140 5 257 2.5E-40 T 29-03-2018 CB4_RS18440 6c789adb3a98bba1d218af71c6432e31 1142 Pfam PF01336 OB-fold nucleic acid binding domain 974 1047 4.8E-7 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CB4_RS18440 6c789adb3a98bba1d218af71c6432e31 1142 Gene3D G3DSA:2.40.50.140 954 1052 2.0E-12 T 29-03-2018 CB4_RS18440 6c789adb3a98bba1d218af71c6432e31 1142 Gene3D G3DSA:1.10.150.280 767 873 1.3E-7 T 29-03-2018 CB4_RS18440 6c789adb3a98bba1d218af71c6432e31 1142 SUPERFAMILY SSF89550 6 264 6.08E-23 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CB4_RS18440 6c789adb3a98bba1d218af71c6432e31 1142 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1011 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18440 6c789adb3a98bba1d218af71c6432e31 1142 Pfam PF14579 Helix-hairpin-helix motif 790 877 6.4E-27 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18440 6c789adb3a98bba1d218af71c6432e31 1142 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 292 716 7.1E-176 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18440 6c789adb3a98bba1d218af71c6432e31 1142 Pfam PF02811 PHP domain 8 174 1.9E-38 T 29-03-2018 IPR004013 PHP domain GO:0003824 CB4_RS18440 6c789adb3a98bba1d218af71c6432e31 1142 SMART SM00481 7 74 7.4E-28 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CB4_RS00765 59540513f1fadc98efa4bdeaff99d3e3 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 7.3E-47 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CB4_RS00765 59540513f1fadc98efa4bdeaff99d3e3 130 SUPERFAMILY SSF54211 6 130 6.07E-49 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS00765 59540513f1fadc98efa4bdeaff99d3e3 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CB4_RS00765 59540513f1fadc98efa4bdeaff99d3e3 130 Gene3D G3DSA:3.30.230.10 3 130 4.6E-52 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS00765 59540513f1fadc98efa4bdeaff99d3e3 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.591 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CB4_RS17655 6f406be545703a9c05f7a9a79afc4629 637 Gene3D G3DSA:3.40.50.300 185 560 3.6E-57 T 29-03-2018 CB4_RS17655 6f406be545703a9c05f7a9a79afc4629 637 Pfam PF01580 FtsK/SpoIIIE family 272 408 8.1E-48 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CB4_RS17655 6f406be545703a9c05f7a9a79afc4629 637 Pfam PF01580 FtsK/SpoIIIE family 417 466 2.7E-15 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CB4_RS17655 6f406be545703a9c05f7a9a79afc4629 637 SUPERFAMILY SSF46785 560 626 2.46E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS17655 6f406be545703a9c05f7a9a79afc4629 637 SMART SM00382 307 487 2.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS17655 6f406be545703a9c05f7a9a79afc4629 637 Pfam PF09397 Ftsk gamma domain 561 622 2.9E-25 T 29-03-2018 IPR018541 FtsK gamma domain CB4_RS17655 6f406be545703a9c05f7a9a79afc4629 637 SMART SM00843 559 625 2.1E-31 T 29-03-2018 IPR018541 FtsK gamma domain CB4_RS17655 6f406be545703a9c05f7a9a79afc4629 637 SUPERFAMILY SSF52540 246 536 1.33E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS17655 6f406be545703a9c05f7a9a79afc4629 637 Gene3D G3DSA:1.10.10.10 561 615 1.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 314 488 3.7E-39 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 Pfam PF00672 HAMP domain 183 227 1.2E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 217 530 7.0E-4 T 29-03-2018 CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 Gene3D G3DSA:1.10.287.950 299 540 3.3E-56 T 29-03-2018 CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 Pfam PF08269 Cache domain 38 146 5.2E-7 T 29-03-2018 IPR004010 Double Cache domain 2 CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 SMART SM00304 182 234 4.1E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 SUPERFAMILY SSF103190 70 142 5.89E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 SUPERFAMILY SSF58104 202 236 1.96E-70 T 29-03-2018 CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 SUPERFAMILY SSF58104 269 538 1.96E-70 T 29-03-2018 CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 Gene3D G3DSA:1.10.287.1060 195 298 8.7E-4 T 29-03-2018 CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 Gene3D G3DSA:3.30.450.20 13 165 3.9E-18 T 29-03-2018 CB4_RS07490 95f278e055d6a139bbaf2625e0b3d8ee 540 SMART SM00283 263 538 1.1E-75 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS01915 7d0980d32acfa4c278d22441c01b5fe0 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.8E-19 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01915 7d0980d32acfa4c278d22441c01b5fe0 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 2 42 4.0E-13 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01915 7d0980d32acfa4c278d22441c01b5fe0 44 Pfam PF00468 Ribosomal protein L34 1 44 1.4E-22 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01915 7d0980d32acfa4c278d22441c01b5fe0 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.439 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS11535 236fef8c9b905cca08640326f25f76ad 1204 SUPERFAMILY SSF55846 732 896 4.71E-41 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CB4_RS11535 236fef8c9b905cca08640326f25f76ad 1204 Gene3D G3DSA:3.40.80.10 730 900 2.1E-44 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CB4_RS11535 236fef8c9b905cca08640326f25f76ad 1204 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 752 880 2.0E-23 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CB4_RS11535 236fef8c9b905cca08640326f25f76ad 1204 Pfam PF01551 Peptidase family M23 101 192 1.1E-31 T 29-03-2018 IPR016047 Peptidase M23 CB4_RS11535 236fef8c9b905cca08640326f25f76ad 1204 Gene3D G3DSA:2.70.70.10 54 212 1.0E-43 T 29-03-2018 CB4_RS11535 236fef8c9b905cca08640326f25f76ad 1204 SMART SM00644 742 886 6.1E-24 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CB4_RS11535 236fef8c9b905cca08640326f25f76ad 1204 SUPERFAMILY SSF51261 82 207 2.25E-50 T 29-03-2018 IPR011055 Duplicated hybrid motif CB4_RS07785 7b24605892614f7d653b482039d934c3 468 Pfam PF01565 FAD binding domain 41 180 1.3E-39 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CB4_RS07785 7b24605892614f7d653b482039d934c3 468 SUPERFAMILY SSF56176 6 217 9.35E-68 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CB4_RS07785 7b24605892614f7d653b482039d934c3 468 SUPERFAMILY SSF55103 221 461 5.4E-70 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CB4_RS07785 7b24605892614f7d653b482039d934c3 468 Gene3D G3DSA:3.30.465.10 94 237 8.2E-41 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CB4_RS07785 7b24605892614f7d653b482039d934c3 468 Gene3D G3DSA:1.10.45.10 418 457 3.4E-18 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CB4_RS07785 7b24605892614f7d653b482039d934c3 468 Gene3D G3DSA:3.30.43.10 2 93 5.5E-21 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CB4_RS07785 7b24605892614f7d653b482039d934c3 468 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 457 9.0E-73 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CB4_RS15120 d2b9abdee696edeeb2a7217fe40eebc2 341 Gene3D G3DSA:3.40.1030.10 70 341 2.9E-107 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS15120 d2b9abdee696edeeb2a7217fe40eebc2 341 Gene3D G3DSA:1.20.970.10 1 68 5.3E-20 T 29-03-2018 CB4_RS15120 d2b9abdee696edeeb2a7217fe40eebc2 341 SUPERFAMILY SSF52418 74 337 1.15E-96 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS15120 d2b9abdee696edeeb2a7217fe40eebc2 341 Pfam PF00591 Glycosyl transferase family, a/b domain 74 322 1.6E-96 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS15120 d2b9abdee696edeeb2a7217fe40eebc2 341 SUPERFAMILY SSF47648 1 68 9.42E-20 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS15120 d2b9abdee696edeeb2a7217fe40eebc2 341 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 332 1.6E-129 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CB4_RS15120 d2b9abdee696edeeb2a7217fe40eebc2 341 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 333 39.326 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CB4_RS15120 d2b9abdee696edeeb2a7217fe40eebc2 341 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 64 4.3E-19 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 Gene3D G3DSA:3.30.450.20 4 124 4.2E-17 T 29-03-2018 CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 SUPERFAMILY SSF52540 143 381 4.09E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 Gene3D G3DSA:1.10.10.60 380 450 1.9E-13 T 29-03-2018 CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 Pfam PF08448 PAS fold 11 110 1.0E-9 T 29-03-2018 IPR013656 PAS fold-4 CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 Gene3D G3DSA:3.40.50.300 125 311 2.9E-25 T 29-03-2018 CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 SMART SM00091 5 71 1.5E-6 T 29-03-2018 IPR000014 PAS domain CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 162 175 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 SUPERFAMILY SSF55785 5 102 2.27E-13 T 29-03-2018 IPR000014 PAS domain CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 Gene3D G3DSA:1.10.8.60 312 379 7.1E-20 T 29-03-2018 CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 351 360 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 115 1.9E-9 T 29-03-2018 IPR000014 PAS domain CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 SMART SM00382 158 302 4.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 Pfam PF02954 Bacterial regulatory protein, Fis family 409 448 1.3E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 225 240 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 Pfam PF00158 Sigma-54 interaction domain 142 306 3.4E-64 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS01735 3f413e54e44254f8c4307ec0a7631b59 451 SUPERFAMILY SSF46689 402 450 1.3E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS18940 65ad255b49977660aace2baeeed08a02 377 Gene3D G3DSA:1.20.1250.20 1 192 2.1E-24 T 29-03-2018 CB4_RS18940 65ad255b49977660aace2baeeed08a02 377 SUPERFAMILY SSF103473 4 375 6.41E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS18940 65ad255b49977660aace2baeeed08a02 377 Pfam PF07690 Major Facilitator Superfamily 204 373 4.7E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS18940 65ad255b49977660aace2baeeed08a02 377 Pfam PF07690 Major Facilitator Superfamily 7 191 1.4E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS18940 65ad255b49977660aace2baeeed08a02 377 Gene3D G3DSA:1.20.1250.20 194 376 2.2E-20 T 29-03-2018 CB4_RS13635 8a97020bc71f958b331e7b6b26bd0799 384 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 10 278 9.9E-74 T 29-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 CB4_RS13635 8a97020bc71f958b331e7b6b26bd0799 384 Gene3D G3DSA:1.20.91.10 222 305 5.7E-15 T 29-03-2018 CB4_RS13635 8a97020bc71f958b331e7b6b26bd0799 384 Pfam PF00999 Sodium/hydrogen exchanger family 8 369 8.8E-75 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CB4_RS03950 4a62b64b1ae7cc125487a5186c6a16cc 378 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 6 375 62.081 T 29-03-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 CB4_RS03950 4a62b64b1ae7cc125487a5186c6a16cc 378 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 10 364 4.4E-85 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CB4_RS03950 4a62b64b1ae7cc125487a5186c6a16cc 378 Pfam PF01546 Peptidase family M20/M25/M40 70 373 4.5E-26 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CB4_RS03950 4a62b64b1ae7cc125487a5186c6a16cc 378 PIRSF PIRSF005962 2 377 1.4E-106 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CB4_RS03950 4a62b64b1ae7cc125487a5186c6a16cc 378 SUPERFAMILY SSF53187 7 192 7.07E-67 T 29-03-2018 CB4_RS03950 4a62b64b1ae7cc125487a5186c6a16cc 378 SUPERFAMILY SSF53187 293 372 7.07E-67 T 29-03-2018 CB4_RS03950 4a62b64b1ae7cc125487a5186c6a16cc 378 Pfam PF07687 Peptidase dimerisation domain 183 271 1.0E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CB4_RS03950 4a62b64b1ae7cc125487a5186c6a16cc 378 Gene3D G3DSA:3.40.630.10 2 275 2.6E-55 T 29-03-2018 CB4_RS03950 4a62b64b1ae7cc125487a5186c6a16cc 378 SUPERFAMILY SSF55031 181 286 8.64E-28 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 Gene3D G3DSA:3.30.450.20 196 322 1.5E-23 T 29-03-2018 CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 481 655 6.0E-43 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 Pfam PF02743 Cache domain 36 305 2.2E-26 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 SMART SM00304 343 398 4.2E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 SMART SM00304 419 472 35.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 SUPERFAMILY SSF58104 372 400 3.79E-71 T 29-03-2018 CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 SUPERFAMILY SSF58104 433 702 3.79E-71 T 29-03-2018 CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 Gene3D G3DSA:1.10.287.950 374 454 7.6E-6 T 29-03-2018 CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 Gene3D G3DSA:1.10.287.950 455 653 5.7E-52 T 29-03-2018 CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 SMART SM00283 427 702 2.6E-75 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS18015 1622897a9d0b0f4ed477d2200203a3a3 704 Gene3D G3DSA:3.30.450.20 62 195 2.9E-19 T 29-03-2018 CB4_RS07630 40bdc36939734345c7f15ec605983a9c 351 PRINTS PR00812 Bacterial general secretion pathway protein F signature 115 143 5.7E-8 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS07630 40bdc36939734345c7f15ec605983a9c 351 PRINTS PR00812 Bacterial general secretion pathway protein F signature 314 328 5.7E-8 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS07630 40bdc36939734345c7f15ec605983a9c 351 PRINTS PR00812 Bacterial general secretion pathway protein F signature 330 349 5.7E-8 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS07630 40bdc36939734345c7f15ec605983a9c 351 Pfam PF00482 Type II secretion system (T2SS), protein F 219 341 6.2E-19 T 29-03-2018 IPR018076 Type II secretion system F domain CB4_RS07630 40bdc36939734345c7f15ec605983a9c 351 Pfam PF00482 Type II secretion system (T2SS), protein F 24 143 1.7E-18 T 29-03-2018 IPR018076 Type II secretion system F domain CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 SUPERFAMILY SSF47384 231 303 7.65E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 Pfam PF13426 PAS domain 123 221 7.8E-5 T 29-03-2018 IPR000014 PAS domain CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 Pfam PF13426 PAS domain 6 76 0.0059 T 29-03-2018 IPR000014 PAS domain CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 SMART SM00388 238 306 2.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 SMART SM00387 348 451 1.4E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 Gene3D G3DSA:1.10.287.130 232 302 2.7E-14 T 29-03-2018 CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 303 2.3E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 Gene3D G3DSA:3.30.565.10 306 452 1.7E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 Gene3D G3DSA:3.30.450.20 112 231 7.5E-11 T 29-03-2018 CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 Gene3D G3DSA:3.30.450.20 1 108 7.1E-4 T 29-03-2018 CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 SUPERFAMILY SSF55785 2 84 6.66E-6 T 29-03-2018 IPR000014 PAS domain CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 113 229 2.5E-7 T 29-03-2018 IPR000014 PAS domain CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 SUPERFAMILY SSF55874 297 450 3.14E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 7.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 7.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 7.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 7.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 SUPERFAMILY SSF55785 113 216 7.99E-8 T 29-03-2018 IPR000014 PAS domain CB4_RS01655 9a8e77eafb04612b06a206b3e75a8060 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 450 6.1E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS11395 3943638885291dbf9639e2ec88da3731 262 Gene3D G3DSA:2.40.50.140 12 97 0.0017 T 29-03-2018 CB4_RS11395 3943638885291dbf9639e2ec88da3731 262 SMART SM00316 89 159 1.1E-11 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS11395 3943638885291dbf9639e2ec88da3731 262 SUPERFAMILY SSF50249 85 163 3.71E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS11395 3943638885291dbf9639e2ec88da3731 262 Gene3D G3DSA:2.40.50.140 98 190 5.2E-14 T 29-03-2018 CB4_RS11395 3943638885291dbf9639e2ec88da3731 262 Pfam PF00575 S1 RNA binding domain 88 152 6.7E-7 T 29-03-2018 IPR003029 S1 domain GO:0003676 CB4_RS03665 ae14ee6e9ac081f70004c7ad8c42a76c 388 Gene3D G3DSA:3.30.930.10 3 332 1.2E-69 T 29-03-2018 CB4_RS03665 ae14ee6e9ac081f70004c7ad8c42a76c 388 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 14 324 2.2E-102 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CB4_RS03665 ae14ee6e9ac081f70004c7ad8c42a76c 388 SUPERFAMILY SSF55681 9 326 8.36E-69 T 29-03-2018 CB4_RS03665 ae14ee6e9ac081f70004c7ad8c42a76c 388 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 19 374 31.255 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CB4_RS03665 ae14ee6e9ac081f70004c7ad8c42a76c 388 PIRSF PIRSF001549 5 379 2.2E-83 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CB4_RS03665 ae14ee6e9ac081f70004c7ad8c42a76c 388 Pfam PF13393 Histidyl-tRNA synthetase 12 320 7.6E-84 T 29-03-2018 CB4_RS08885 1ea90810e46c6b466cc39049fcb11045 100 Gene3D G3DSA:1.20.58.130 7 99 2.3E-4 T 29-03-2018 CB4_RS13055 6689b41b951beab11db92cbffb09d282 140 Gene3D G3DSA:2.170.270.10 1 119 6.6E-20 T 29-03-2018 CB4_RS13055 6689b41b951beab11db92cbffb09d282 140 SUPERFAMILY SSF82199 12 114 6.41E-22 T 29-03-2018 CB4_RS13055 6689b41b951beab11db92cbffb09d282 140 SMART SM00317 2 117 6.5E-6 T 29-03-2018 IPR001214 SET domain GO:0005515 CB4_RS13055 6689b41b951beab11db92cbffb09d282 140 Pfam PF00856 SET domain 60 111 1.3E-9 T 29-03-2018 IPR001214 SET domain GO:0005515 CB4_RS13055 6689b41b951beab11db92cbffb09d282 140 PIRSF PIRSF022536 1 130 2.4E-32 T 29-03-2018 IPR009207 Histone methyltransferase, PBCV type putative KEGG: 00310+2.1.1.43 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 Pfam PF00403 Heavy-metal-associated domain 73 130 1.0E-9 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 SUPERFAMILY SSF81653 259 356 3.66E-24 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 Gene3D G3DSA:3.40.1110.10 479 580 5.3E-24 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00941 Cadmium-transporting ATPase signature 84 105 9.8E-28 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00941 Cadmium-transporting ATPase signature 322 338 9.8E-28 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00941 Cadmium-transporting ATPase signature 241 261 9.8E-28 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00941 Cadmium-transporting ATPase signature 73 82 9.8E-28 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00941 Cadmium-transporting ATPase signature 341 355 9.8E-28 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00941 Cadmium-transporting ATPase signature 170 187 9.8E-28 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 SUPERFAMILY SSF55008 66 136 6.28E-16 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 Gene3D G3DSA:3.30.70.100 69 136 1.3E-16 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 206 759 8.5E-192 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 SUPERFAMILY SSF56784 455 475 1.12E-56 T 29-03-2018 IPR023214 HAD-like domain CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 SUPERFAMILY SSF56784 513 757 1.12E-56 T 29-03-2018 IPR023214 HAD-like domain CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 Pfam PF00702 haloacid dehalogenase-like hydrolase 454 670 9.9E-42 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 Gene3D G3DSA:1.20.1110.10 150 478 6.3E-44 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 194 759 5.1E-127 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 459 465 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 207 523 1.4E-101 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 603 613 3.3E-24 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 306 320 3.3E-24 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 675 3.3E-24 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 580 591 3.3E-24 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 680 692 3.3E-24 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 457 471 3.3E-24 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 Gene3D G3DSA:3.40.50.1000 581 723 1.0E-40 T 29-03-2018 IPR023214 HAD-like domain CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 SUPERFAMILY SSF81665 206 260 8.5E-18 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 SUPERFAMILY SSF81665 357 451 8.5E-18 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 SUPERFAMILY SSF81665 706 749 8.5E-18 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 Pfam PF00122 E1-E2 ATPase 257 437 5.9E-55 T 29-03-2018 CB4_RS13200 55be018d466640dad2ebe24e38d59ecb 764 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 228 736 8.8E-91 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS00035 6c862f39dc143848d12b6262481a4bfc 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 1.2E-22 T 29-03-2018 IPR012452 Protein of unknown function DUF1657 CB4_RS00035 6c862f39dc143848d12b6262481a4bfc 68 Gene3D G3DSA:1.20.1260.10 2 67 4.0E-4 T 29-03-2018 IPR012347 Ferritin-related CB4_RS00530 9638f22215049f3e1349612e26847663 160 Pfam PF05163 DinB family 5 154 1.8E-13 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CB4_RS00530 9638f22215049f3e1349612e26847663 160 Gene3D G3DSA:1.20.120.450 1 151 1.2E-22 T 29-03-2018 CB4_RS00530 9638f22215049f3e1349612e26847663 160 SUPERFAMILY SSF109854 1 152 1.01E-29 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 293 1.3E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 SUPERFAMILY SSF51905 2 301 4.25E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 1.1E-74 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 1.1E-74 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 1.1E-74 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 233 254 1.1E-74 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 285 1.1E-74 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.1E-74 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.1E-74 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 1.1E-74 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 1.1E-74 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 Gene3D G3DSA:3.50.50.60 1 128 1.2E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 Gene3D G3DSA:3.50.50.60 129 181 2.9E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 304 9.4E-122 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.8E-37 T 29-03-2018 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.8E-37 T 29-03-2018 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 1.8E-37 T 29-03-2018 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.8E-37 T 29-03-2018 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.8E-37 T 29-03-2018 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CB4_RS03795 d9147c87be27fce5f8943dc6226ba3b7 318 Gene3D G3DSA:3.50.50.60 182 310 3.3E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS12535 d3d4b7fa197f8ec7fefcb802687cadcc 185 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 74 163 1.6E-26 T 29-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 CB4_RS19240 13336f182b35adb5fef5a13e2aa59127 229 SUPERFAMILY SSF52540 2 218 6.82E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19240 13336f182b35adb5fef5a13e2aa59127 229 SMART SM00382 26 202 1.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS19240 13336f182b35adb5fef5a13e2aa59127 229 Pfam PF00005 ABC transporter 17 152 8.9E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS19240 13336f182b35adb5fef5a13e2aa59127 229 Gene3D G3DSA:3.40.50.300 1 229 6.7E-55 T 29-03-2018 CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 SUPERFAMILY SSF55383 417 506 7.85E-15 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 190 266 6.1E-9 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Gene3D G3DSA:2.120.10.30 283 391 1.8E-12 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Gene3D G3DSA:2.120.10.30 220 282 1.9E-8 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Gene3D G3DSA:2.120.10.30 113 164 1.3E-7 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Gene3D G3DSA:2.120.10.30 35 112 1.2E-4 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Pfam PF07833 Copper amine oxidase N-terminal domain 411 510 3.9E-21 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Pfam PF07833 Copper amine oxidase N-terminal domain 394 441 1.5E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Gene3D G3DSA:2.120.10.30 165 219 2.7E-8 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 SUPERFAMILY SSF101898 59 381 2.43E-46 T 29-03-2018 CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Pfam PF01436 NHL repeat 296 322 3.7E-4 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Pfam PF01436 NHL repeat 123 149 3.3E-4 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Gene3D G3DSA:3.30.457.10 491 513 3.6E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS18610 c0c6db0befe2299307ad8b550a21045a 513 Gene3D G3DSA:3.30.457.10 415 490 1.2E-15 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Gene3D G3DSA:3.90.1800.10 1070 1114 8.0E-12 T 29-03-2018 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Pfam PF04563 RNA polymerase beta subunit 29 452 7.2E-30 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Pfam PF04560 RNA polymerase Rpb2, domain 7 1069 1143 2.2E-27 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 SUPERFAMILY SSF64484 14 286 0.0 T 29-03-2018 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 SUPERFAMILY SSF64484 376 1153 0.0 T 29-03-2018 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Pfam PF10385 RNA polymerase beta subunit external 1 domain 546 612 2.0E-23 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Pfam PF04565 RNA polymerase Rpb2, domain 3 467 535 7.2E-31 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Gene3D G3DSA:2.40.50.100 670 749 9.1E-27 T 29-03-2018 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Gene3D G3DSA:2.40.270.10 750 848 6.2E-12 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 894 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Pfam PF00562 RNA polymerase Rpb2, domain 6 675 1067 5.7E-169 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Pfam PF04561 RNA polymerase Rpb2, domain 2 371 408 2.4E-7 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 9.1E-28 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Gene3D G3DSA:3.90.1100.10 273 601 7.0E-83 T 29-03-2018 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Gene3D G3DSA:3.90.1100.10 602 669 2.6E-13 T 29-03-2018 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Gene3D G3DSA:3.90.1100.10 20 243 2.0E-58 T 29-03-2018 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 ProSitePatterns PS01166 RNA polymerases beta chain signature. 920 932 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1145 12.678 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS01130 423ac2d6e5cd0e58642c6b8fb631b80c 1175 Gene3D G3DSA:2.40.270.10 849 1053 2.5E-81 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 SMART SM00448 688 802 2.8E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Gene3D G3DSA:2.60.120.260 47 224 6.6E-11 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Pfam PF00072 Response regulator receiver domain 690 802 4.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 SUPERFAMILY SSF55874 874 1009 6.42E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Gene3D G3DSA:3.40.50.2300 680 884 2.0E-35 T 29-03-2018 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 SUPERFAMILY SSF55874 486 655 4.58E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Gene3D G3DSA:3.30.565.10 885 1010 6.0E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 SMART SM00387 912 1013 0.033 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 SMART SM00387 543 654 6.4E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Pfam PF06580 Histidine kinase 819 898 1.3E-21 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Pfam PF00512 His Kinase A (phospho-acceptor) domain 430 497 9.8E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 SUPERFAMILY SSF49785 49 193 3.06E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 607 5.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 PRINTS PR00344 Bacterial sensor protein C-terminal signature 614 632 5.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 PRINTS PR00344 Bacterial sensor protein C-terminal signature 579 593 5.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 PRINTS PR00344 Bacterial sensor protein C-terminal signature 638 651 5.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Gene3D G3DSA:3.30.565.10 503 663 9.4E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 SMART SM00388 429 497 1.6E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Pfam PF07695 7TM diverse intracellular signalling 210 406 7.1E-16 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 SUPERFAMILY SSF52172 689 833 1.71E-36 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 544 652 6.2E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 917 1010 2.8E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 Gene3D G3DSA:1.10.287.130 419 493 9.0E-16 T 29-03-2018 CB4_RS13865 ae56d2813130e9e8dd358234fdf989c3 1015 SUPERFAMILY SSF47384 419 498 1.02E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS20170 e4b42d7ad4c2c09a6492d15b45ac5f96 230 SUPERFAMILY SSF46785 7 74 1.81E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS20170 e4b42d7ad4c2c09a6492d15b45ac5f96 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 7.3E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS20170 e4b42d7ad4c2c09a6492d15b45ac5f96 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 6.8E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS20170 e4b42d7ad4c2c09a6492d15b45ac5f96 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 6.8E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS20170 e4b42d7ad4c2c09a6492d15b45ac5f96 230 Gene3D G3DSA:1.10.10.10 3 77 2.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS20170 e4b42d7ad4c2c09a6492d15b45ac5f96 230 SMART SM00895 94 221 1.5E-18 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS20170 e4b42d7ad4c2c09a6492d15b45ac5f96 230 SMART SM00345 11 70 9.6E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS20170 e4b42d7ad4c2c09a6492d15b45ac5f96 230 SUPERFAMILY SSF48008 90 226 1.23E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS20170 e4b42d7ad4c2c09a6492d15b45ac5f96 230 Pfam PF07729 FCD domain 95 219 4.8E-23 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS20170 e4b42d7ad4c2c09a6492d15b45ac5f96 230 Gene3D G3DSA:1.20.120.530 87 230 5.4E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 PIRSF PIRSF001438 1 308 1.5E-123 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 293 39.012 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 293 7.7E-110 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 291 2.0E-17 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 SUPERFAMILY SSF53850 2 216 2.44E-82 T 29-03-2018 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 1.6E-81 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 8.4E-50 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 8.4E-50 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 8.4E-50 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 8.4E-50 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 PRINTS PR00151 Porphobilinogen deaminase signature 228 245 8.4E-50 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 Gene3D G3DSA:3.40.190.10 1 104 2.2E-42 T 29-03-2018 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 Gene3D G3DSA:3.40.190.10 105 197 9.3E-38 T 29-03-2018 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 229 245 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 Gene3D G3DSA:3.30.160.40 218 302 1.3E-21 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS05670 0e15fdb58424b16cecc23c408ce4fd83 308 SUPERFAMILY SSF54782 218 303 3.53E-22 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS18790 0b2e82ee17d56a2cdfa9abaa3b4b67bf 493 SUPERFAMILY SSF53041 1 153 5.75E-25 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18790 0b2e82ee17d56a2cdfa9abaa3b4b67bf 493 SMART SM00857 3 153 4.1E-32 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18790 0b2e82ee17d56a2cdfa9abaa3b4b67bf 493 Gene3D G3DSA:3.40.50.1390 1 159 9.7E-29 T 29-03-2018 CB4_RS18790 0b2e82ee17d56a2cdfa9abaa3b4b67bf 493 Pfam PF00239 Resolvase, N terminal domain 3 152 6.5E-27 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18790 0b2e82ee17d56a2cdfa9abaa3b4b67bf 493 Pfam PF07508 Recombinase 174 262 2.1E-17 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 SUPERFAMILY SSF54637 302 430 5.34E-19 T 29-03-2018 IPR029069 HotDog domain CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 SMART SM00116 200 248 5.1 T 29-03-2018 IPR000644 CBS domain CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 SMART SM00116 259 307 1.0E-5 T 29-03-2018 IPR000644 CBS domain CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 Gene3D G3DSA:3.10.129.10 301 436 2.2E-25 T 29-03-2018 CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 59 3.9E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 Gene3D G3DSA:1.10.10.10 3 69 2.8E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 Pfam PF00571 CBS domain 203 244 2.4E-4 T 29-03-2018 IPR000644 CBS domain CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 Pfam PF00571 CBS domain 253 307 4.1E-7 T 29-03-2018 IPR000644 CBS domain CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 Pfam PF03061 Thioesterase superfamily 351 424 2.0E-8 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 SUPERFAMILY SSF46785 4 59 8.44E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 SUPERFAMILY SSF54631 182 307 3.41E-29 T 29-03-2018 CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 Gene3D G3DSA:3.40.1390.20 70 190 3.2E-27 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 SUPERFAMILY SSF75138 72 185 4.97E-29 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 Gene3D G3DSA:3.10.580.10 191 300 2.6E-23 T 29-03-2018 CB4_RS18495 8424f298d0936ec36a9e6e0c4b88d1ca 436 Pfam PF07085 DRTGG domain 76 178 7.9E-29 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CB4_RS06325 5a70a6e4cbf22100349c202ce8429cce 450 Pfam PF04286 Protein of unknown function (DUF445) 43 435 1.9E-68 T 29-03-2018 IPR007383 Protein of unknown function DUF445 CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 Pfam PF00106 short chain dehydrogenase 6 201 1.6E-56 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 SUPERFAMILY SSF51735 4 246 5.63E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 Gene3D G3DSA:3.40.50.720 39 246 2.7E-56 T 29-03-2018 CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 Gene3D G3DSA:3.40.50.720 1 38 8.5E-9 T 29-03-2018 CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 9.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 9.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 9.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS07045 c3029c5239eaef2b41797cdd22e481c5 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CB4_RS04915 11e4f223cb345e55148276fb4e00895e 151 Gene3D G3DSA:3.40.630.30 90 144 1.8E-9 T 29-03-2018 CB4_RS04915 11e4f223cb345e55148276fb4e00895e 151 Gene3D G3DSA:3.40.630.30 1 89 1.2E-15 T 29-03-2018 CB4_RS04915 11e4f223cb345e55148276fb4e00895e 151 SUPERFAMILY SSF55729 4 143 8.1E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS04915 11e4f223cb345e55148276fb4e00895e 151 Pfam PF00583 Acetyltransferase (GNAT) family 33 139 6.5E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 Gene3D G3DSA:1.10.1160.10 271 347 4.8E-35 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 10 560 51.829 T 29-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 PRINTS PR00987 Glutamyl-tRNA synthetase signature 220 230 4.5E-9 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 PRINTS PR00987 Glutamyl-tRNA synthetase signature 71 84 4.5E-9 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 PRINTS PR00987 Glutamyl-tRNA synthetase signature 42 54 4.5E-9 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 39 347 1.2E-115 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 39 560 3.4E-229 T 29-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 Gene3D G3DSA:2.40.240.10 475 558 3.1E-34 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 56 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 SUPERFAMILY SSF50715 350 558 2.25E-75 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 Gene3D G3DSA:3.40.50.620 166 270 5.9E-23 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 Gene3D G3DSA:3.40.50.620 52 163 7.0E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 Gene3D G3DSA:2.40.240.10 354 474 3.3E-50 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 Gene3D G3DSA:3.40.50.620 19 51 0.015 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 SUPERFAMILY SSF52374 22 346 5.12E-101 T 29-03-2018 CB4_RS19245 74d94b60cfac5b55849de80f458c1509 565 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 351 539 1.5E-59 T 29-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 Gene3D G3DSA:3.40.47.10 264 389 4.5E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 4.6E-141 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 SUPERFAMILY SSF53901 5 268 1.27E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 Pfam PF00108 Thiolase, N-terminal domain 5 262 7.9E-102 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 SUPERFAMILY SSF53901 270 391 2.45E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 Pfam PF02803 Thiolase, C-terminal domain 270 390 6.4E-44 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 Gene3D G3DSA:3.40.47.10 161 263 1.1E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 Gene3D G3DSA:3.40.47.10 1 160 6.4E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 PIRSF PIRSF000429 1 393 5.6E-122 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS02755 545ece6945a703f1ceec34066c337f21 394 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CB4_RS08410 ccd0b2aeece0f998b5306e6eec012c71 240 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 230 4.2E-47 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS08410 ccd0b2aeece0f998b5306e6eec012c71 240 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 4 236 39.192 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS08410 ccd0b2aeece0f998b5306e6eec012c71 240 SUPERFAMILY SSF51366 1 236 3.83E-70 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CB4_RS08410 ccd0b2aeece0f998b5306e6eec012c71 240 Gene3D G3DSA:3.20.20.70 2 236 8.3E-64 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS08410 ccd0b2aeece0f998b5306e6eec012c71 240 SMART SM00934 6 231 3.4E-86 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS08410 ccd0b2aeece0f998b5306e6eec012c71 240 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 8 231 4.1E-57 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS08410 ccd0b2aeece0f998b5306e6eec012c71 240 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 58 71 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS10275 889f67822a4d1f57815d12fa917ad0d8 312 SUPERFAMILY SSF54001 120 234 1.57E-21 T 29-03-2018 CB4_RS10275 889f67822a4d1f57815d12fa917ad0d8 312 Pfam PF01841 Transglutaminase-like superfamily 127 225 1.1E-11 T 29-03-2018 IPR002931 Transglutaminase-like CB4_RS10275 889f67822a4d1f57815d12fa917ad0d8 312 SMART SM00460 167 228 7.2E-9 T 29-03-2018 IPR002931 Transglutaminase-like CB4_RS19260 2b21ff124b543acb1e99d698d3ac8fe6 142 Gene3D G3DSA:3.40.630.30 1 73 4.9E-12 T 29-03-2018 CB4_RS19260 2b21ff124b543acb1e99d698d3ac8fe6 142 PIRSF PIRSF037663 1 138 3.0E-12 T 29-03-2018 IPR017255 Acetyltransferase, GNAT, predicted CB4_RS19260 2b21ff124b543acb1e99d698d3ac8fe6 142 SUPERFAMILY SSF55729 2 127 1.36E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS19260 2b21ff124b543acb1e99d698d3ac8fe6 142 Pfam PF00583 Acetyltransferase (GNAT) family 18 123 1.1E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS19260 2b21ff124b543acb1e99d698d3ac8fe6 142 Gene3D G3DSA:3.40.630.30 74 128 2.1E-16 T 29-03-2018 CB4_RS02480 eaa35ccaa7022a8b3ce1289162486d12 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 263 3.3E-62 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CB4_RS02480 eaa35ccaa7022a8b3ce1289162486d12 264 SUPERFAMILY SSF52096 9 263 3.61E-79 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS02480 eaa35ccaa7022a8b3ce1289162486d12 264 Gene3D G3DSA:3.90.226.10 1 205 5.9E-63 T 29-03-2018 CB4_RS02480 eaa35ccaa7022a8b3ce1289162486d12 264 Gene3D G3DSA:1.10.12.10 208 264 7.0E-12 T 29-03-2018 IPR014748 Crontonase, C-terminal CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 SMART SM00091 321 390 3.1E-7 T 29-03-2018 IPR000014 PAS domain CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 SMART SM00091 196 261 6.7E-6 T 29-03-2018 IPR000014 PAS domain CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 SUPERFAMILY SSF47384 447 513 2.94E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 SUPERFAMILY SSF55785 207 317 4.94E-20 T 29-03-2018 IPR000014 PAS domain CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 SMART SM00388 453 515 1.1E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 Pfam PF00512 His Kinase A (phospho-acceptor) domain 455 512 1.4E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 558 660 8.0E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 Gene3D G3DSA:3.30.450.20 315 445 7.4E-37 T 29-03-2018 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 Gene3D G3DSA:1.10.287.130 446 511 2.7E-12 T 29-03-2018 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 Gene3D G3DSA:3.30.450.20 181 314 2.4E-24 T 29-03-2018 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 SMART SM00387 556 662 6.9E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 Pfam PF13426 PAS domain 207 307 4.9E-11 T 29-03-2018 IPR000014 PAS domain CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 Pfam PF08447 PAS fold 344 428 3.2E-16 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 593 607 7.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 646 659 7.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 622 640 7.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 611 621 7.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 SMART SM00086 396 438 2.0E-9 T 29-03-2018 IPR001610 PAC motif CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 SMART SM00086 267 309 1.5 T 29-03-2018 IPR001610 PAC motif CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 Gene3D G3DSA:3.30.565.10 515 664 1.1E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 319 444 3.0E-20 T 29-03-2018 IPR000014 PAS domain CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 199 316 8.6E-21 T 29-03-2018 IPR000014 PAS domain CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 SUPERFAMILY SSF55874 505 660 5.76E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00390 ecf9dbb823e681277c3a8011cce1784c 664 SUPERFAMILY SSF55785 306 436 1.65E-25 T 29-03-2018 IPR000014 PAS domain CB4_RS14885 b2c7a502acfe3a4cb76e8e113d0a6225 278 SMART SM00450 153 270 3.9E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS14885 b2c7a502acfe3a4cb76e8e113d0a6225 278 SMART SM00450 5 131 8.6E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS14885 b2c7a502acfe3a4cb76e8e113d0a6225 278 Pfam PF00581 Rhodanese-like domain 155 265 1.2E-14 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS14885 b2c7a502acfe3a4cb76e8e113d0a6225 278 Pfam PF00581 Rhodanese-like domain 6 128 2.4E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS14885 b2c7a502acfe3a4cb76e8e113d0a6225 278 SUPERFAMILY SSF52821 3 151 5.76E-38 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS14885 b2c7a502acfe3a4cb76e8e113d0a6225 278 Gene3D G3DSA:3.40.250.10 147 278 1.0E-27 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS14885 b2c7a502acfe3a4cb76e8e113d0a6225 278 Gene3D G3DSA:3.40.250.10 1 146 3.5E-30 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS14885 b2c7a502acfe3a4cb76e8e113d0a6225 278 SUPERFAMILY SSF52821 150 272 6.55E-34 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS08255 80d7208f19b64b4f96b730015100d40a 365 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 355 5.8E-98 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CB4_RS08255 80d7208f19b64b4f96b730015100d40a 365 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 361 34.285 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CB4_RS08255 80d7208f19b64b4f96b730015100d40a 365 Gene3D G3DSA:3.40.50.2000 178 345 1.6E-27 T 29-03-2018 CB4_RS08255 80d7208f19b64b4f96b730015100d40a 365 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 4.2E-46 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CB4_RS08255 80d7208f19b64b4f96b730015100d40a 365 SUPERFAMILY SSF53756 1 361 8.8E-107 T 29-03-2018 CB4_RS08255 80d7208f19b64b4f96b730015100d40a 365 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 349 5.3E-36 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CB4_RS08255 80d7208f19b64b4f96b730015100d40a 365 Gene3D G3DSA:3.40.50.2000 1 177 4.8E-39 T 29-03-2018 CB4_RS10610 96151d234242376aa88407dfa2fee0d9 216 SUPERFAMILY SSF69118 12 106 2.36E-27 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CB4_RS10610 96151d234242376aa88407dfa2fee0d9 216 SUPERFAMILY SSF69118 132 214 1.57E-22 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CB4_RS10610 96151d234242376aa88407dfa2fee0d9 216 Gene3D G3DSA:1.20.1290.10 116 216 9.5E-22 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CB4_RS10610 96151d234242376aa88407dfa2fee0d9 216 Gene3D G3DSA:1.20.1290.10 3 115 8.4E-25 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CB4_RS10610 96151d234242376aa88407dfa2fee0d9 216 Pfam PF02627 Carboxymuconolactone decarboxylase family 133 214 7.6E-19 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CB4_RS10610 96151d234242376aa88407dfa2fee0d9 216 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 106 2.8E-22 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CB4_RS10610 96151d234242376aa88407dfa2fee0d9 216 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 41 89 2.1E-17 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CB4_RS10610 96151d234242376aa88407dfa2fee0d9 216 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 153 200 2.3E-15 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CB4_RS16105 f57819b907b9e653799ac99cc1a606e7 407 Gene3D G3DSA:3.30.9.10 86 158 4.5E-5 T 29-03-2018 CB4_RS16105 f57819b907b9e653799ac99cc1a606e7 407 SUPERFAMILY SSF51905 1 283 1.21E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16105 f57819b907b9e653799ac99cc1a606e7 407 SUPERFAMILY SSF51905 327 346 1.21E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16105 f57819b907b9e653799ac99cc1a606e7 407 Gene3D G3DSA:3.30.9.10 159 347 5.1E-34 T 29-03-2018 CB4_RS16105 f57819b907b9e653799ac99cc1a606e7 407 Pfam PF01266 FAD dependent oxidoreductase 3 390 5.8E-67 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CB4_RS20310 5e187f171a57ae55368a196352882f5e 330 SUPERFAMILY SSF53901 5 328 1.25E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS20310 5e187f171a57ae55368a196352882f5e 330 Gene3D G3DSA:3.40.47.10 6 166 3.2E-36 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS20310 5e187f171a57ae55368a196352882f5e 330 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 8 328 2.7E-109 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS20310 5e187f171a57ae55368a196352882f5e 330 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 7 328 65.455 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS20310 5e187f171a57ae55368a196352882f5e 330 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 240 328 4.4E-30 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS20310 5e187f171a57ae55368a196352882f5e 330 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 112 190 3.8E-31 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS20310 5e187f171a57ae55368a196352882f5e 330 Gene3D G3DSA:3.40.47.10 167 327 1.2E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS00285 816ae86b75b46ef2f059247a9f98fbd8 266 SUPERFAMILY SSF53927 7 263 5.72E-77 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CB4_RS00285 816ae86b75b46ef2f059247a9f98fbd8 266 Gene3D G3DSA:3.40.140.10 128 266 2.9E-47 T 29-03-2018 CB4_RS00285 816ae86b75b46ef2f059247a9f98fbd8 266 Gene3D G3DSA:3.10.20.10 29 110 1.9E-19 T 29-03-2018 CB4_RS00285 816ae86b75b46ef2f059247a9f98fbd8 266 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 3 263 31.29 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CB4_RS00285 816ae86b75b46ef2f059247a9f98fbd8 266 Pfam PF02634 FdhD/NarQ family 27 262 1.1E-77 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CB4_RS00285 816ae86b75b46ef2f059247a9f98fbd8 266 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 23 262 2.4E-73 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CB4_RS00285 816ae86b75b46ef2f059247a9f98fbd8 266 PIRSF PIRSF015626 1 266 1.4E-80 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Pfam PF00384 Molybdopterin oxidoreductase 317 737 3.0E-70 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 SMART SM00929 86 127 2.8E-12 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 193 204 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 SUPERFAMILY SSF54862 131 217 1.23E-17 T 29-03-2018 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 PIRSF PIRSF036643 2 968 0.0 T 29-03-2018 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Gene3D G3DSA:3.40.50.740 319 515 2.8E-44 T 29-03-2018 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 5 78 8.9E-17 T 29-03-2018 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 261 314 9.8E-19 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 SUPERFAMILY SSF53706 255 777 8.25E-190 T 29-03-2018 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 SUPERFAMILY SSF50692 788 935 7.25E-37 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Gene3D G3DSA:3.10.20.30 1 126 2.8E-16 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Gene3D G3DSA:2.40.40.20 784 936 3.6E-30 T 29-03-2018 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Gene3D G3DSA:3.40.50.740 516 783 1.0E-78 T 29-03-2018 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Gene3D G3DSA:3.30.70.20 198 265 0.036 T 29-03-2018 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Gene3D G3DSA:2.20.25.90 266 318 3.1E-19 T 29-03-2018 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 125 7.0E-10 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 265 934 1.5E-251 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Pfam PF12838 4Fe-4S dicluster domain 149 207 9.2E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Gene3D G3DSA:3.30.70.20 131 197 6.4E-13 T 29-03-2018 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 Pfam PF01568 Molydopterin dinucleotide binding domain 825 930 5.3E-22 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 SUPERFAMILY SSF54292 7 129 4.5E-31 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CB4_RS00275 cef710bffa2681e2d85313e74bdc616d 984 SMART SM00926 260 314 1.7E-19 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS10315 7dc2eb51163e687b84fc109a856efdec 222 SMART SM00862 147 220 7.3E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS10315 7dc2eb51163e687b84fc109a856efdec 222 Gene3D G3DSA:1.10.10.10 121 222 5.8E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS10315 7dc2eb51163e687b84fc109a856efdec 222 Pfam PF00072 Response regulator receiver domain 6 115 1.1E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS10315 7dc2eb51163e687b84fc109a856efdec 222 SMART SM00448 4 114 3.5E-46 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS10315 7dc2eb51163e687b84fc109a856efdec 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 220 4.8E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS10315 7dc2eb51163e687b84fc109a856efdec 222 Gene3D G3DSA:3.40.50.2300 2 120 3.6E-40 T 29-03-2018 CB4_RS10315 7dc2eb51163e687b84fc109a856efdec 222 SUPERFAMILY SSF52172 3 182 2.99E-47 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS06445 b314733cef2dc316699e0805fd333150 410 SMART SM00257 4 48 2.0E-8 T 29-03-2018 IPR018392 LysM domain CB4_RS06445 b314733cef2dc316699e0805fd333150 410 SMART SM00257 53 97 4.8E-5 T 29-03-2018 IPR018392 LysM domain CB4_RS06445 b314733cef2dc316699e0805fd333150 410 SUPERFAMILY SSF54106 52 97 8.76E-6 T 29-03-2018 IPR018392 LysM domain CB4_RS06445 b314733cef2dc316699e0805fd333150 410 Pfam PF01476 LysM domain 5 47 2.0E-11 T 29-03-2018 IPR018392 LysM domain CB4_RS06445 b314733cef2dc316699e0805fd333150 410 Pfam PF01476 LysM domain 54 97 1.7E-7 T 29-03-2018 IPR018392 LysM domain CB4_RS06445 b314733cef2dc316699e0805fd333150 410 SMART SM00631 111 388 8.2E-36 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CB4_RS06445 b314733cef2dc316699e0805fd333150 410 Gene3D G3DSA:3.40.630.10 107 398 2.3E-48 T 29-03-2018 CB4_RS06445 b314733cef2dc316699e0805fd333150 410 SUPERFAMILY SSF53187 111 393 9.26E-55 T 29-03-2018 CB4_RS06445 b314733cef2dc316699e0805fd333150 410 Gene3D G3DSA:3.10.350.10 51 102 1.2E-8 T 29-03-2018 CB4_RS06445 b314733cef2dc316699e0805fd333150 410 SUPERFAMILY SSF54106 3 47 3.79E-8 T 29-03-2018 IPR018392 LysM domain CB4_RS06445 b314733cef2dc316699e0805fd333150 410 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 251 259 7.4E-7 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CB4_RS06445 b314733cef2dc316699e0805fd333150 410 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 305 318 7.4E-7 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CB4_RS06445 b314733cef2dc316699e0805fd333150 410 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 135 147 7.4E-7 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CB4_RS06445 b314733cef2dc316699e0805fd333150 410 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 154 168 7.4E-7 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CB4_RS06445 b314733cef2dc316699e0805fd333150 410 Pfam PF00246 Zinc carboxypeptidase 120 335 8.2E-38 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CB4_RS06445 b314733cef2dc316699e0805fd333150 410 Gene3D G3DSA:3.10.350.10 2 49 4.7E-11 T 29-03-2018 CB4_RS20220 c8dad2a00cd0c9b9abbbf38c7ba0c347 256 PIRSF PIRSF006157 1 256 1.6E-94 T 29-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 CB4_RS20220 c8dad2a00cd0c9b9abbbf38c7ba0c347 256 Gene3D G3DSA:3.40.830.10 1 256 8.0E-90 T 29-03-2018 CB4_RS20220 c8dad2a00cd0c9b9abbbf38c7ba0c347 256 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 20 249 1.7E-47 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CB4_RS20220 c8dad2a00cd0c9b9abbbf38c7ba0c347 256 SUPERFAMILY SSF53213 1 256 1.44E-92 T 29-03-2018 CB4_RS15000 5e1509a80b73ef74a85f45c497f06a7f 267 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 129 2.7E-31 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS15000 5e1509a80b73ef74a85f45c497f06a7f 267 Gene3D G3DSA:3.30.360.10 131 235 1.3E-36 T 29-03-2018 CB4_RS15000 5e1509a80b73ef74a85f45c497f06a7f 267 Gene3D G3DSA:3.40.50.720 1 125 1.3E-30 T 29-03-2018 CB4_RS15000 5e1509a80b73ef74a85f45c497f06a7f 267 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 132 265 5.5E-32 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS15000 5e1509a80b73ef74a85f45c497f06a7f 267 SUPERFAMILY SSF51735 3 154 1.92E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS15000 5e1509a80b73ef74a85f45c497f06a7f 267 PIRSF PIRSF000161 2 267 2.9E-66 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS15000 5e1509a80b73ef74a85f45c497f06a7f 267 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 151 168 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS15000 5e1509a80b73ef74a85f45c497f06a7f 267 SUPERFAMILY SSF55347 130 238 1.74E-37 T 29-03-2018 CB4_RS15000 5e1509a80b73ef74a85f45c497f06a7f 267 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 267 29.266 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS15000 5e1509a80b73ef74a85f45c497f06a7f 267 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 266 1.8E-86 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS06905 b52c04d0ef973cf0f31328a1e035b9d9 531 Pfam PF14107 Domain of unknown function (DUF4280) 16 116 9.2E-19 T 29-03-2018 IPR025460 Protein of unknown function DUF4280 CB4_RS12335 b204041d1b673e1dbf17a5c9048f9d2b 494 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 18 484 6.3E-190 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS12335 b204041d1b673e1dbf17a5c9048f9d2b 494 PIRSF PIRSF005690 5 494 1.5E-188 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 SMART SM00283 379 654 9.3E-81 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 Gene3D G3DSA:1.10.287.950 325 412 3.6E-7 T 29-03-2018 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 Gene3D G3DSA:1.10.287.950 413 655 1.7E-54 T 29-03-2018 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 506 535 3.9E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 3.9E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 Gene3D G3DSA:3.30.450.20 28 157 1.5E-10 T 29-03-2018 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 SMART SM00304 298 350 3.9E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 SUPERFAMILY SSF58104 318 352 1.31E-73 T 29-03-2018 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 SUPERFAMILY SSF58104 385 654 1.31E-73 T 29-03-2018 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 Pfam PF02743 Cache domain 35 260 5.3E-21 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 Pfam PF00672 HAMP domain 299 340 2.6E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 423 607 8.9E-48 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS12885 8a11b7cad3cbfc5a4a690de0dbe7f452 655 Gene3D G3DSA:3.30.450.20 158 277 1.6E-20 T 29-03-2018 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 SMART SM00283 302 577 8.8E-90 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 SUPERFAMILY SSF58104 308 576 2.49E-72 T 29-03-2018 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 SUPERFAMILY SSF58104 247 275 2.49E-72 T 29-03-2018 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 Pfam PF00672 HAMP domain 220 269 3.9E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 Gene3D G3DSA:3.30.450.20 30 190 3.0E-8 T 29-03-2018 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 427 1.0E-22 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 429 458 1.0E-22 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 10 35 1.0E-22 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 347 530 9.2E-50 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 Gene3D G3DSA:1.10.287.950 526 577 0.21 T 29-03-2018 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 Gene3D G3DSA:1.10.287.950 325 525 5.7E-53 T 29-03-2018 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 Gene3D G3DSA:1.10.287.950 247 324 3.9E-4 T 29-03-2018 CB4_RS14415 98ce73e05f7f234c9e5fd8a76054c12a 578 SMART SM00304 220 273 1.9E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS03270 08b91c56f451970b9e50b5d6b6f52106 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 1.4E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS03270 08b91c56f451970b9e50b5d6b6f52106 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 1.4E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS03270 08b91c56f451970b9e50b5d6b6f52106 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 1.4E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS03270 08b91c56f451970b9e50b5d6b6f52106 147 Gene3D G3DSA:1.10.10.10 1 134 2.2E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03270 08b91c56f451970b9e50b5d6b6f52106 147 SUPERFAMILY SSF46785 5 139 3.37E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03270 08b91c56f451970b9e50b5d6b6f52106 147 SMART SM00347 25 125 4.8E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS03270 08b91c56f451970b9e50b5d6b6f52106 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 59 78 2.7E-5 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS03270 08b91c56f451970b9e50b5d6b6f52106 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 48 59 2.7E-5 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS03270 08b91c56f451970b9e50b5d6b6f52106 147 Pfam PF01047 MarR family 32 90 5.3E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS14695 641877a855b2fafe6649f925644d4eba 367 Pfam PF01385 Probable transposase 169 275 2.3E-23 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS14695 641877a855b2fafe6649f925644d4eba 367 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 316 2.1E-13 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS14695 641877a855b2fafe6649f925644d4eba 367 Pfam PF12323 Helix-turn-helix domain 1 48 5.7E-20 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CB4_RS14695 641877a855b2fafe6649f925644d4eba 367 Pfam PF07282 Putative transposase DNA-binding domain 289 359 2.6E-23 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS14695 641877a855b2fafe6649f925644d4eba 367 Gene3D G3DSA:1.20.1270.60 191 295 0.0019 T 29-03-2018 CB4_RS20375 25aaaa2136f2fee1981eaba78ab70263 230 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 206 3.5E-46 T 29-03-2018 CB4_RS20375 25aaaa2136f2fee1981eaba78ab70263 230 SUPERFAMILY SSF52317 1 218 8.03E-77 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS20375 25aaaa2136f2fee1981eaba78ab70263 230 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 44.196 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS20375 25aaaa2136f2fee1981eaba78ab70263 230 PIRSF PIRSF001586 1 223 3.2E-88 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS20375 25aaaa2136f2fee1981eaba78ab70263 230 SMART SM01211 1 220 1.3E-132 T 29-03-2018 CB4_RS20375 25aaaa2136f2fee1981eaba78ab70263 230 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 219 5.2E-96 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS20375 25aaaa2136f2fee1981eaba78ab70263 230 Gene3D G3DSA:3.40.50.880 1 222 2.2E-37 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS19320 59531d9dcb6c5b87e68a0f52bee133fb 371 Pfam PF00188 Cysteine-rich secretory protein family 261 365 2.1E-15 T 29-03-2018 IPR014044 CAP domain CB4_RS19320 59531d9dcb6c5b87e68a0f52bee133fb 371 SUPERFAMILY SSF55797 259 369 1.57E-20 T 29-03-2018 IPR014044 CAP domain CB4_RS19320 59531d9dcb6c5b87e68a0f52bee133fb 371 Gene3D G3DSA:3.40.33.10 244 370 6.8E-15 T 29-03-2018 IPR014044 CAP domain CB4_RS19320 59531d9dcb6c5b87e68a0f52bee133fb 371 Pfam PF14504 CAP-associated N-terminal 94 225 1.0E-15 T 29-03-2018 IPR029410 CAP-associated domain CB4_RS07200 9d620d3e4cdb5dd6b0c12b2d83837b68 396 Gene3D G3DSA:3.60.21.10 165 392 1.1E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS07200 9d620d3e4cdb5dd6b0c12b2d83837b68 396 Gene3D G3DSA:1.10.260.40 1 85 3.3E-11 T 29-03-2018 CB4_RS07200 9d620d3e4cdb5dd6b0c12b2d83837b68 396 SMART SM00530 11 66 1.1E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS07200 9d620d3e4cdb5dd6b0c12b2d83837b68 396 SMART SM00854 160 371 1.5E-10 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CB4_RS07200 9d620d3e4cdb5dd6b0c12b2d83837b68 396 SUPERFAMILY SSF47413 3 68 9.29E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS07200 9d620d3e4cdb5dd6b0c12b2d83837b68 396 SUPERFAMILY SSF56300 238 378 4.48E-15 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS07200 9d620d3e4cdb5dd6b0c12b2d83837b68 396 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 227 366 7.7E-30 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CB4_RS07200 9d620d3e4cdb5dd6b0c12b2d83837b68 396 Pfam PF01381 Helix-turn-helix 12 65 2.7E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 Gene3D G3DSA:3.40.50.150 237 613 4.1E-40 T 29-03-2018 CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 476 482 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 Pfam PF02384 N-6 DNA Methylase 470 579 1.2E-9 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 SUPERFAMILY SSF53335 127 259 1.56E-64 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 SUPERFAMILY SSF53335 294 358 1.56E-64 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 SUPERFAMILY SSF53335 467 635 1.56E-64 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 SUPERFAMILY SSF53335 74 100 1.56E-64 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 298 312 2.5E-12 T 29-03-2018 CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 240 256 2.5E-12 T 29-03-2018 CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 504 528 2.5E-12 T 29-03-2018 CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 473 485 2.5E-12 T 29-03-2018 CB4_RS19630 ce796682abae6fd7b588386d7cc088db 1158 Gene3D G3DSA:3.90.220.10 630 820 1.4E-20 T 29-03-2018 CB4_RS09820 0dd761a3833e27c7b9dbb75003ec8797 69 Pfam PF01614 Bacterial transcriptional regulator 7 62 4.6E-11 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CB4_RS09820 0dd761a3833e27c7b9dbb75003ec8797 69 SUPERFAMILY SSF55781 6 67 7.19E-14 T 29-03-2018 IPR029016 GAF domain-like CB4_RS09820 0dd761a3833e27c7b9dbb75003ec8797 69 Gene3D G3DSA:3.30.450.40 4 69 3.7E-15 T 29-03-2018 IPR029016 GAF domain-like CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 SUPERFAMILY SSF88659 273 374 5.42E-30 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 Pfam PF03979 Sigma-70 factor, region 1.1 16 89 3.4E-18 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 Pfam PF04542 Sigma-70 region 2 143 212 3.8E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 SUPERFAMILY SSF88946 104 213 1.44E-54 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 139 364 1.7E-39 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 Pfam PF04539 Sigma-70 region 3 222 298 2.2E-32 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 PRINTS PR00046 Major sigma-70 factor signature 167 180 2.4E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 PRINTS PR00046 Major sigma-70 factor signature 191 199 2.4E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 PRINTS PR00046 Major sigma-70 factor signature 315 327 2.4E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 PRINTS PR00046 Major sigma-70 factor signature 336 351 2.4E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 PRINTS PR00046 Major sigma-70 factor signature 351 362 2.4E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 336 362 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 Pfam PF00140 Sigma-70 factor, region 1.2 105 138 2.2E-18 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 Gene3D G3DSA:1.10.10.10 213 263 2.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 Gene3D G3DSA:1.10.10.10 305 376 5.2E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 SUPERFAMILY SSF88659 216 289 5.23E-24 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 167 180 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 Pfam PF04545 Sigma-70, region 4 311 364 5.7E-20 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 5 376 34.751 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 139 375 2.7E-125 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CB4_RS07155 dafae89c466780ce2f919f4b69ceffdc 376 Gene3D G3DSA:1.10.601.10 1 212 2.2E-79 T 29-03-2018 CB4_RS18925 93011bdf64e9364c3fd213189b853e15 178 Gene3D G3DSA:1.10.10.10 84 170 1.6E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18925 93011bdf64e9364c3fd213189b853e15 178 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 138 144 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CB4_RS18925 93011bdf64e9364c3fd213189b853e15 178 Gene3D G3DSA:3.30.160.70 2 83 7.7E-22 T 29-03-2018 CB4_RS18925 93011bdf64e9364c3fd213189b853e15 178 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 89 169 5.5E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CB4_RS18925 93011bdf64e9364c3fd213189b853e15 178 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 9 168 39.759 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CB4_RS18925 93011bdf64e9364c3fd213189b853e15 178 SUPERFAMILY SSF53155 4 92 5.49E-20 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CB4_RS18925 93011bdf64e9364c3fd213189b853e15 178 SUPERFAMILY SSF46767 87 169 8.63E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CB4_RS18925 93011bdf64e9364c3fd213189b853e15 178 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 4 84 3.7E-11 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CB4_RS18925 93011bdf64e9364c3fd213189b853e15 178 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 88 167 1.6E-33 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CB4_RS12605 7ba29e02bb50ffd1611cdbc3bbbc629b 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.3E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12605 7ba29e02bb50ffd1611cdbc3bbbc629b 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.3E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12605 7ba29e02bb50ffd1611cdbc3bbbc629b 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.3E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12605 7ba29e02bb50ffd1611cdbc3bbbc629b 111 SMART SM00418 3 84 5.3E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12605 7ba29e02bb50ffd1611cdbc3bbbc629b 111 SUPERFAMILY SSF46785 5 94 1.07E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12605 7ba29e02bb50ffd1611cdbc3bbbc629b 111 Gene3D G3DSA:1.10.10.10 1 104 6.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12605 7ba29e02bb50ffd1611cdbc3bbbc629b 111 Pfam PF12840 Helix-turn-helix domain 6 57 4.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02615 543db16a61a5e9b073577beb1f138f52 126 Pfam PF04241 Protein of unknown function (DUF423) 19 106 3.4E-28 T 29-03-2018 IPR006696 Protein of unknown function DUF423 CB4_RS00805 2fb8defa3c13fb3f37ac856b5c56426a 297 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS00805 2fb8defa3c13fb3f37ac856b5c56426a 297 Pfam PF00005 ABC transporter 23 174 2.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS00805 2fb8defa3c13fb3f37ac856b5c56426a 297 SUPERFAMILY SSF52540 3 240 6.3E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00805 2fb8defa3c13fb3f37ac856b5c56426a 297 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 260 6.8E-106 T 29-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 CB4_RS00805 2fb8defa3c13fb3f37ac856b5c56426a 297 SMART SM00382 32 222 3.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS00805 2fb8defa3c13fb3f37ac856b5c56426a 297 Gene3D G3DSA:3.40.50.300 1 248 3.3E-58 T 29-03-2018 CB4_RS15650 447281d1233de90b2aa21dc18134dcb4 234 SUPERFAMILY SSF52833 48 223 8.41E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS15650 447281d1233de90b2aa21dc18134dcb4 234 Pfam PF13462 Thioredoxin 51 222 1.4E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS15650 447281d1233de90b2aa21dc18134dcb4 234 Gene3D G3DSA:3.40.30.10 51 231 1.1E-37 T 29-03-2018 CB4_RS01175 937c01caaf0c8000a04f4910f0b2ef0a 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01175 937c01caaf0c8000a04f4910f0b2ef0a 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 1.1E-19 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01175 937c01caaf0c8000a04f4910f0b2ef0a 49 Pfam PF00471 Ribosomal protein L33 3 49 4.6E-22 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01175 937c01caaf0c8000a04f4910f0b2ef0a 49 SUPERFAMILY SSF57829 1 49 1.1E-18 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CB4_RS01175 937c01caaf0c8000a04f4910f0b2ef0a 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.663 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS13945 18f749924e4c35c99ff07245a8c8c132 774 Gene3D G3DSA:3.30.470.20 140 241 2.8E-23 T 29-03-2018 CB4_RS13945 18f749924e4c35c99ff07245a8c8c132 774 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 64 187 5.5E-26 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CB4_RS13945 18f749924e4c35c99ff07245a8c8c132 774 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 203 243 5.8E-8 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CB4_RS13945 18f749924e4c35c99ff07245a8c8c132 774 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 63 2.2E-5 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CB4_RS13945 18f749924e4c35c99ff07245a8c8c132 774 SUPERFAMILY SSF52009 666 772 8.37E-30 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CB4_RS13945 18f749924e4c35c99ff07245a8c8c132 774 Pfam PF00391 PEP-utilising enzyme, mobile domain 698 769 3.8E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CB4_RS13945 18f749924e4c35c99ff07245a8c8c132 774 Gene3D G3DSA:3.50.30.10 671 774 5.1E-34 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CB4_RS13945 18f749924e4c35c99ff07245a8c8c132 774 Gene3D G3DSA:3.30.1490.20 1 53 1.2E-8 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS13945 18f749924e4c35c99ff07245a8c8c132 774 Gene3D G3DSA:3.30.1490.20 54 139 2.4E-16 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS13945 18f749924e4c35c99ff07245a8c8c132 774 SUPERFAMILY SSF56059 1 282 2.35E-54 T 29-03-2018 CB4_RS04665 b6e8f4535a4d67fa897ecad7a3bc1f73 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 40.727 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CB4_RS04665 b6e8f4535a4d67fa897ecad7a3bc1f73 126 SUPERFAMILY SSF51230 3 125 4.84E-47 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS04665 b6e8f4535a4d67fa897ecad7a3bc1f73 126 Pfam PF01597 Glycine cleavage H-protein 7 126 4.1E-50 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CB4_RS04665 b6e8f4535a4d67fa897ecad7a3bc1f73 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 125 4.7E-57 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CB4_RS04665 b6e8f4535a4d67fa897ecad7a3bc1f73 126 Gene3D G3DSA:2.40.50.100 5 126 1.6E-51 T 29-03-2018 CB4_RS04665 b6e8f4535a4d67fa897ecad7a3bc1f73 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CB4_RS01910 58b532ca8318068a713e828804af99c3 451 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 361 427 1.2E-29 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CB4_RS01910 58b532ca8318068a713e828804af99c3 451 Pfam PF00308 Bacterial dnaA protein 114 330 6.8E-107 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CB4_RS01910 58b532ca8318068a713e828804af99c3 451 SUPERFAMILY SSF48295 345 449 1.15E-35 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CB4_RS01910 58b532ca8318068a713e828804af99c3 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 211 225 3.2E-52 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CB4_RS01910 58b532ca8318068a713e828804af99c3 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 245 272 3.2E-52 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CB4_RS01910 58b532ca8318068a713e828804af99c3 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 179 193 3.2E-52 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CB4_RS01910 58b532ca8318068a713e828804af99c3 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 408 427 3.2E-52 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CB4_RS01910 58b532ca8318068a713e828804af99c3 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 147 167 3.2E-52 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CB4_RS01910 58b532ca8318068a713e828804af99c3 451 Gene3D G3DSA:3.40.50.300 111 278 1.9E-22 T 29-03-2018 CB4_RS01910 58b532ca8318068a713e828804af99c3 451 Gene3D G3DSA:1.10.1750.10 352 449 3.1E-33 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CB4_RS01910 58b532ca8318068a713e828804af99c3 451 SMART SM00760 358 427 3.9E-40 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CB4_RS01910 58b532ca8318068a713e828804af99c3 451 SUPERFAMILY SSF52540 114 326 7.89E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01910 58b532ca8318068a713e828804af99c3 451 ProSitePatterns PS01008 DnaA protein signature. 408 427 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CB4_RS01910 58b532ca8318068a713e828804af99c3 451 Gene3D G3DSA:1.10.8.60 280 351 1.3E-28 T 29-03-2018 CB4_RS01910 58b532ca8318068a713e828804af99c3 451 Pfam PF11638 DnaA N-terminal domain 7 68 4.9E-19 T 29-03-2018 IPR024633 DnaA N-terminal domain CB4_RS01910 58b532ca8318068a713e828804af99c3 451 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 9 448 6.8E-185 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CB4_RS01910 58b532ca8318068a713e828804af99c3 451 SMART SM00382 146 274 2.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS01910 58b532ca8318068a713e828804af99c3 451 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 6 449 34.91 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CB4_RS07520 e8a3f2ddce2668277fae5981a01440ed 399 Gene3D G3DSA:1.20.1540.10 180 361 7.1E-38 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CB4_RS07520 e8a3f2ddce2668277fae5981a01440ed 399 Pfam PF01694 Rhomboid family 224 360 1.6E-34 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CB4_RS07520 e8a3f2ddce2668277fae5981a01440ed 399 SUPERFAMILY SSF144091 180 362 3.14E-42 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 Gene3D G3DSA:1.20.5.50 271 420 1.3E-4 T 29-03-2018 CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 SUPERFAMILY SSF52540 988 1180 3.61E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 SUPERFAMILY SSF52540 1 207 3.61E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 636 1.1E-27 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 SMART SM00968 519 638 1.2E-37 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 Gene3D G3DSA:1.20.5.340 171 270 0.014 T 29-03-2018 CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1179 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1181 24.282 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 SUPERFAMILY SSF75553 481 685 1.26E-54 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 Gene3D G3DSA:3.40.50.300 1 170 1.6E-41 T 29-03-2018 CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 Gene3D G3DSA:1.20.1000.10 487 772 3.2E-4 T 29-03-2018 CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 664 5.9E-43 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 Pfam PF02463 RecF/RecN/SMC N terminal domain 863 1172 4.2E-34 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 PIRSF PIRSF005719 1 1185 0.0 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein CB4_RS08645 0e230654b9b48fb6fbbca2e83f6a62f0 1185 Gene3D G3DSA:3.40.50.300 843 1185 9.7E-29 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:2.60.120.640 319 417 3.6E-16 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:2.60.40.10 421 502 0.17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 197 207 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF00395 S-layer homology domain 1207 1248 2.5E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF00395 S-layer homology domain 1269 1308 3.1E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF00395 S-layer homology domain 1148 1187 5.8E-15 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 119 129 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:3.10.100.10 187 226 9.1E-15 T 29-03-2018 IPR016186 C-type lectin-like/link domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:3.10.100.10 227 265 2.7E-13 T 29-03-2018 IPR016186 C-type lectin-like/link domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:3.10.100.10 149 186 3.8E-13 T 29-03-2018 IPR016186 C-type lectin-like/link domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:3.10.100.10 70 109 1.3E-13 T 29-03-2018 IPR016186 C-type lectin-like/link domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:3.10.100.10 266 307 3.0E-9 T 29-03-2018 IPR016186 C-type lectin-like/link domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:3.10.100.10 110 148 2.3E-13 T 29-03-2018 IPR016186 C-type lectin-like/link domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:3.10.100.10 22 69 1.5E-8 T 29-03-2018 IPR016186 C-type lectin-like/link domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 273 302 6.5E-7 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 155 184 5.5E-11 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 77 106 5.2E-10 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 42 68 3.4E-6 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 116 145 2.5E-9 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 194 223 1.4E-11 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 233 262 4.0E-11 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 236 246 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:2.60.40.1080 701 791 0.0055 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Gene3D G3DSA:2.60.40.1080 503 597 7.3E-4 T 29-03-2018 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 SUPERFAMILY SSF50985 41 148 1.83E-30 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF12733 Cadherin-like beta sandwich domain 411 500 2.2E-19 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 Pfam PF12733 Cadherin-like beta sandwich domain 810 888 3.7E-18 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 SUPERFAMILY SSF50985 113 303 1.77E-49 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 158 168 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CB4_RS09595 f3d5d91f98a1bc255c7c8fb0b30f720b 1319 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 80 90 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CB4_RS13915 e2c3f2fd5a56bed470fad1d6096f985c 275 SUPERFAMILY SSF89550 10 269 2.35E-51 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CB4_RS13915 e2c3f2fd5a56bed470fad1d6096f985c 275 Gene3D G3DSA:3.20.20.140 8 272 1.4E-42 T 29-03-2018 CB4_RS13915 e2c3f2fd5a56bed470fad1d6096f985c 275 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 10 251 3.2E-51 T 29-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 CB4_RS13915 e2c3f2fd5a56bed470fad1d6096f985c 275 Pfam PF02811 PHP domain 11 205 2.4E-12 T 29-03-2018 IPR004013 PHP domain GO:0003824 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 SUPERFAMILY SSF52374 4 225 8.23E-155 T 29-03-2018 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 SUPERFAMILY SSF52374 420 628 8.23E-155 T 29-03-2018 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 Gene3D G3DSA:1.10.730.10 610 755 4.7E-37 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 818 23.244 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 421 621 2.1E-23 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 171 1.8E-26 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 Gene3D G3DSA:3.90.740.10 231 406 3.3E-54 T 29-03-2018 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 SUPERFAMILY SSF47323 624 818 2.43E-39 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 220 407 5.2E-74 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 8.6E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 563 573 8.6E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 8.6E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 491 509 8.6E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 8.6E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 530 552 8.6E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 214 233 8.6E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 SUPERFAMILY SSF50677 225 419 1.36E-52 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 Gene3D G3DSA:3.40.50.620 407 609 1.6E-71 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS06565 c633448fb89196929731eee287a92cdb 819 Gene3D G3DSA:3.40.50.620 1 230 2.3E-79 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS06565 c633448fb89196929731eee287a92cdb 819 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 52 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 Pfam PF08264 Anticodon-binding domain of tRNA 660 781 1.7E-22 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CB4_RS06565 c633448fb89196929731eee287a92cdb 819 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 818 0.0 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Pfam PF14579 Helix-hairpin-helix motif 1351 1431 2.2E-10 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 235 1438 0.0 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Pfam PF14480 DNA polymerase III polC-type N-terminus I 12 83 9.9E-20 T 29-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Pfam PF11490 DNA polymerase III polC-type N-terminus II 98 206 2.9E-7 T 29-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1438 411.004 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 SUPERFAMILY SSF50249 254 316 3.94E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Gene3D G3DSA:3.20.20.140 598 797 6.3E-21 T 29-03-2018 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 418 635 2.2E-44 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Gene3D G3DSA:1.20.5.140 566 593 1.4E-8 T 29-03-2018 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Gene3D G3DSA:2.40.50.140 224 325 1.7E-20 T 29-03-2018 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Gene3D G3DSA:3.30.420.10 412 562 2.2E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 826 1244 3.5E-99 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 SMART SM00479 424 590 1.3E-49 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Gene3D G3DSA:1.10.150.280 1376 1426 0.0026 T 29-03-2018 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Pfam PF01336 OB-fold nucleic acid binding domain 255 321 1.5E-6 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 SUPERFAMILY SSF53098 424 878 1.18E-100 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Pfam PF02811 PHP domain 340 695 5.2E-47 T 29-03-2018 IPR004013 PHP domain GO:0003824 CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 SMART SM00481 339 406 2.0E-27 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CB4_RS09305 eb2b8cd1f51c502625d80a99d9eb09fa 1438 Pfam PF00929 Exonuclease 426 581 1.5E-35 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 Gene3D G3DSA:3.30.450.20 66 207 6.7E-4 T 29-03-2018 CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 1.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 429 1.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 410 1.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 385 1.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 Gene3D G3DSA:1.10.287.130 208 267 2.9E-13 T 29-03-2018 CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 SMART SM00388 203 271 3.0E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 SUPERFAMILY SSF47384 188 271 1.26E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 SMART SM00387 316 432 2.4E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 SUPERFAMILY SSF55874 261 431 5.76E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 Pfam PF00512 His Kinase A (phospho-acceptor) domain 204 271 1.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 Gene3D G3DSA:3.30.565.10 275 440 3.7E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13755 469aac79ee27e4e57f3324d2f07f84f3 440 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 431 6.8E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS07720 a05a610505511a83bec5a5523575d532 229 Gene3D G3DSA:3.20.70.20 2 228 1.9E-43 T 29-03-2018 CB4_RS07720 a05a610505511a83bec5a5523575d532 229 SUPERFAMILY SSF51998 87 226 1.71E-32 T 29-03-2018 CB4_RS07720 a05a610505511a83bec5a5523575d532 229 Pfam PF02867 Ribonucleotide reductase, barrel domain 149 226 2.1E-15 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 Gene3D G3DSA:3.80.30.20 208 443 4.9E-55 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 215 235 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 Pfam PF04055 Radical SAM superfamily 215 387 2.0E-33 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 66 503 72.407 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 67 501 2.1E-188 T 29-03-2018 CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 SMART SM00729 211 429 1.1E-64 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 67 499 7.0E-156 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 Gene3D G3DSA:2.40.50.140 444 504 3.2E-4 T 29-03-2018 CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 Pfam PF00919 Uncharacterized protein family UPF0004 68 168 1.1E-26 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 SUPERFAMILY SSF102114 200 439 7.72E-64 T 29-03-2018 CB4_RS14725 a94852057038d02de1a71b957ad9bd00 507 Pfam PF01938 TRAM domain 442 501 1.7E-9 T 29-03-2018 IPR002792 TRAM domain CB4_RS18105 7ffc9d7b32e67ead45633408f6521f83 136 Gene3D G3DSA:3.10.129.10 1 131 5.6E-17 T 29-03-2018 CB4_RS18105 7ffc9d7b32e67ead45633408f6521f83 136 Pfam PF03061 Thioesterase superfamily 38 105 3.6E-5 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS18105 7ffc9d7b32e67ead45633408f6521f83 136 SUPERFAMILY SSF54637 2 128 9.26E-32 T 29-03-2018 IPR029069 HotDog domain CB4_RS00165 67f67c92d3fdf03d37c8d2a1ba55de59 140 SUPERFAMILY SSF46785 4 134 1.36E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00165 67f67c92d3fdf03d37c8d2a1ba55de59 140 Gene3D G3DSA:1.10.10.10 6 92 2.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00165 67f67c92d3fdf03d37c8d2a1ba55de59 140 Pfam PF01475 Ferric uptake regulator family 12 129 5.8E-29 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CB4_RS08405 b3534fba63035188905d4123851d5bd0 305 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 5 304 1.3E-122 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CB4_RS08405 b3534fba63035188905d4123851d5bd0 305 Pfam PF01180 Dihydroorotate dehydrogenase 5 288 4.9E-93 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CB4_RS08405 b3534fba63035188905d4123851d5bd0 305 Gene3D G3DSA:3.20.20.70 1 305 6.7E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS08405 b3534fba63035188905d4123851d5bd0 305 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 5 303 41.7 T 29-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CB4_RS08405 b3534fba63035188905d4123851d5bd0 305 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 241 261 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CB4_RS08405 b3534fba63035188905d4123851d5bd0 305 SUPERFAMILY SSF51395 4 304 1.94E-86 T 29-03-2018 CB4_RS08405 b3534fba63035188905d4123851d5bd0 305 PIRSF PIRSF000164 1 305 1.6E-86 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CB4_RS08405 b3534fba63035188905d4123851d5bd0 305 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 41 60 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 Gene3D G3DSA:3.40.120.10 339 457 3.1E-38 T 29-03-2018 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 512 553 8.6E-9 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 Gene3D G3DSA:3.30.310.50 474 580 1.6E-20 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 Gene3D G3DSA:3.40.120.10 15 213 1.0E-54 T 29-03-2018 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 SUPERFAMILY SSF55957 515 569 2.35E-14 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 SUPERFAMILY SSF55957 446 483 2.35E-14 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 SUPERFAMILY SSF53738 208 317 2.18E-17 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 42 177 1.8E-40 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 314 7.9E-21 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 SUPERFAMILY SSF53738 28 237 1.73E-46 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 Gene3D G3DSA:3.40.120.10 214 338 1.3E-28 T 29-03-2018 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 5.3E-5 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 5.3E-5 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 327 453 1.9E-23 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS16750 1d4e7dea7e641fc05a12a07f765bfb98 582 SUPERFAMILY SSF53738 306 456 9.81E-33 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS02980 959211160d984fd9201dfc66833ad370 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 58.518 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CB4_RS02980 959211160d984fd9201dfc66833ad370 466 SUPERFAMILY SSF50615 3 80 3.92E-27 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS02980 959211160d984fd9201dfc66833ad370 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS02980 959211160d984fd9201dfc66833ad370 466 SMART SM00382 147 387 1.3E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS02980 959211160d984fd9201dfc66833ad370 466 Gene3D G3DSA:3.40.50.300 81 354 1.3E-94 T 29-03-2018 CB4_RS02980 959211160d984fd9201dfc66833ad370 466 SUPERFAMILY SSF47917 351 465 8.11E-53 T 29-03-2018 CB4_RS02980 959211160d984fd9201dfc66833ad370 466 Gene3D G3DSA:1.10.1140.10 355 464 7.5E-44 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS02980 959211160d984fd9201dfc66833ad370 466 SUPERFAMILY SSF52540 82 354 3.21E-93 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02980 959211160d984fd9201dfc66833ad370 466 Gene3D G3DSA:2.40.10.170 1 80 1.4E-31 T 29-03-2018 CB4_RS02980 959211160d984fd9201dfc66833ad370 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 348 6.3E-67 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS02980 959211160d984fd9201dfc66833ad370 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 78 1.8E-22 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS02980 959211160d984fd9201dfc66833ad370 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 1.5E-260 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CB4_RS01930 8552fd63a1c523e84f72e2d7106551df 252 Pfam PF13083 KH domain 110 176 1.9E-13 T 29-03-2018 CB4_RS01930 8552fd63a1c523e84f72e2d7106551df 252 Gene3D G3DSA:3.30.30.80 3 54 2.7E-20 T 29-03-2018 CB4_RS01930 8552fd63a1c523e84f72e2d7106551df 252 Gene3D G3DSA:3.30.300.20 102 179 2.7E-21 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CB4_RS01930 8552fd63a1c523e84f72e2d7106551df 252 SUPERFAMILY SSF82708 192 247 2.94E-9 T 29-03-2018 IPR001374 R3H domain GO:0003676 CB4_RS01930 8552fd63a1c523e84f72e2d7106551df 252 SMART SM01245 5 57 1.8E-22 T 29-03-2018 IPR032782 Jag, N-terminal CB4_RS01930 8552fd63a1c523e84f72e2d7106551df 252 Gene3D G3DSA:3.30.1370.50 181 252 1.2E-19 T 29-03-2018 IPR001374 R3H domain GO:0003676 CB4_RS01930 8552fd63a1c523e84f72e2d7106551df 252 SMART SM00393 170 249 1.6E-20 T 29-03-2018 IPR001374 R3H domain GO:0003676 CB4_RS01930 8552fd63a1c523e84f72e2d7106551df 252 Pfam PF01424 R3H domain 189 247 5.6E-15 T 29-03-2018 IPR001374 R3H domain GO:0003676 CB4_RS01930 8552fd63a1c523e84f72e2d7106551df 252 Pfam PF14804 Jag N-terminus 6 55 1.1E-20 T 29-03-2018 IPR032782 Jag, N-terminal CB4_RS12595 5afff676423db875d9d391080557d4f9 309 SUPERFAMILY SSF88659 102 182 1.03E-8 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS12595 5afff676423db875d9d391080557d4f9 309 Gene3D G3DSA:1.10.1740.10 18 87 2.8E-12 T 29-03-2018 CB4_RS12595 5afff676423db875d9d391080557d4f9 309 Gene3D G3DSA:1.10.10.10 88 167 4.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12595 5afff676423db875d9d391080557d4f9 309 SUPERFAMILY SSF88946 20 101 6.67E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS12595 5afff676423db875d9d391080557d4f9 309 Gene3D G3DSA:3.10.450.50 168 308 4.5E-6 T 29-03-2018 CB4_RS12595 5afff676423db875d9d391080557d4f9 309 SUPERFAMILY SSF54427 184 301 2.07E-6 T 29-03-2018 IPR032710 NTF2-like domain CB4_RS12595 5afff676423db875d9d391080557d4f9 309 Pfam PF08281 Sigma-70, region 4 127 174 2.4E-8 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS12595 5afff676423db875d9d391080557d4f9 309 Pfam PF04542 Sigma-70 region 2 23 87 1.9E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS12595 5afff676423db875d9d391080557d4f9 309 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 176 4.0E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS04780 0929a609bf0a025bbe4c85e36e8579be 100 Gene3D G3DSA:3.30.1980.10 1 99 4.4E-39 T 29-03-2018 CB4_RS04780 0929a609bf0a025bbe4c85e36e8579be 100 Pfam PF08827 Domain of unknown function (DUF1805) 37 99 5.6E-24 T 29-03-2018 IPR014931 Protein of unknown function DUF1805 CB4_RS04780 0929a609bf0a025bbe4c85e36e8579be 100 SUPERFAMILY SSF102891 1 99 2.75E-33 T 29-03-2018 IPR014931 Protein of unknown function DUF1805 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 SMART SM00480 17 374 6.2E-152 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 PIRSF PIRSF000804 1 379 1.4E-116 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 SUPERFAMILY SSF55979 1 127 5.94E-27 T 29-03-2018 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 Gene3D G3DSA:3.10.150.10 130 257 2.9E-31 T 29-03-2018 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 SUPERFAMILY SSF55979 135 252 4.99E-26 T 29-03-2018 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 255 377 7.8E-33 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 Gene3D G3DSA:3.10.150.10 258 379 2.2E-23 T 29-03-2018 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 Gene3D G3DSA:3.10.150.10 1 129 1.7E-30 T 29-03-2018 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 SUPERFAMILY SSF55979 255 378 5.07E-31 T 29-03-2018 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 7.7E-36 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 252 5.9E-33 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS01905 6bebb377da787439fff1b5a84ffce326 380 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 378 1.7E-111 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS00160 bebbf54a3b8cb1f6ffac665097d0c84e 234 Gene3D G3DSA:3.10.450.40 178 234 1.5E-9 T 29-03-2018 CB4_RS00160 bebbf54a3b8cb1f6ffac665097d0c84e 234 Gene3D G3DSA:3.10.450.40 114 169 2.5E-4 T 29-03-2018 CB4_RS00160 bebbf54a3b8cb1f6ffac665097d0c84e 234 Gene3D G3DSA:3.10.450.40 48 105 4.3E-9 T 29-03-2018 CB4_RS09455 03fea7f93c303e701838a1ce0d3e8138 554 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 361 407 1.6E-9 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CB4_RS09455 03fea7f93c303e701838a1ce0d3e8138 554 SMART SM00849 21 216 1.7E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS09455 03fea7f93c303e701838a1ce0d3e8138 554 Hamap MF_01491 Ribonuclease J [rnj]. 4 554 47.835 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CB4_RS09455 03fea7f93c303e701838a1ce0d3e8138 554 SUPERFAMILY SSF56281 10 423 1.18E-100 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS09455 03fea7f93c303e701838a1ce0d3e8138 554 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 6.1E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS09455 03fea7f93c303e701838a1ce0d3e8138 554 Gene3D G3DSA:3.60.15.10 2 447 1.8E-65 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS09455 03fea7f93c303e701838a1ce0d3e8138 554 PIRSF PIRSF004803 1 554 7.7E-246 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CB4_RS09455 03fea7f93c303e701838a1ce0d3e8138 554 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 363 391 - T 29-03-2018 IPR001587 Ribonuclease J, conserved site CB4_RS09455 03fea7f93c303e701838a1ce0d3e8138 554 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 552 5.3E-207 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CB4_RS08335 8fffd02e8b6219dff4415dfc7c6c6a4f 230 Gene3D G3DSA:3.20.20.10 1 229 3.6E-62 T 29-03-2018 IPR029066 PLP-binding barrel CB4_RS08335 8fffd02e8b6219dff4415dfc7c6c6a4f 230 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 227 4.1E-57 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CB4_RS08335 8fffd02e8b6219dff4415dfc7c6c6a4f 230 PIRSF PIRSF004848 1 230 1.9E-72 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CB4_RS08335 8fffd02e8b6219dff4415dfc7c6c6a4f 230 SUPERFAMILY SSF51419 1 226 3.01E-75 T 29-03-2018 IPR029066 PLP-binding barrel CB4_RS08335 8fffd02e8b6219dff4415dfc7c6c6a4f 230 Pfam PF01168 Alanine racemase, N-terminal domain 10 227 3.2E-21 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CB4_RS16865 3704d5e687a7227903ae6e1ad51771b0 189 Pfam PF06803 Protein of unknown function (DUF1232) 98 130 4.9E-9 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 350 535 4.1E-32 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 6 535 5.0E-266 T 29-03-2018 IPR014251 Sporulation protease LonB CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 265 2.0E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 Gene3D G3DSA:1.10.8.60 256 335 4.3E-12 T 29-03-2018 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 Gene3D G3DSA:3.40.50.300 48 255 3.8E-33 T 29-03-2018 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 SUPERFAMILY SSF54211 352 535 6.07E-39 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 494 512 1.1E-33 T 29-03-2018 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 471 490 1.1E-33 T 29-03-2018 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 441 460 1.1E-33 T 29-03-2018 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 97 116 1.1E-33 T 29-03-2018 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 368 1.1E-33 T 29-03-2018 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 SUPERFAMILY SSF52540 55 204 5.35E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 SUPERFAMILY SSF52540 235 328 5.35E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 Gene3D G3DSA:3.30.230.10 348 553 7.5E-51 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 444 452 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 173 188 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CB4_RS05625 21cdbf2c2aa986943ef8281b82bfb061 560 SMART SM00382 89 267 2.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS01210 e4a1060e0a9ffac221182e7df2e6acc1 219 Gene3D G3DSA:2.160.10.10 53 218 5.5E-40 T 29-03-2018 CB4_RS01210 e4a1060e0a9ffac221182e7df2e6acc1 219 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 2.5E-4 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CB4_RS01210 e4a1060e0a9ffac221182e7df2e6acc1 219 Gene3D G3DSA:1.10.3130.10 1 52 1.2E-27 T 29-03-2018 CB4_RS01210 e4a1060e0a9ffac221182e7df2e6acc1 219 SUPERFAMILY SSF51161 5 168 1.16E-57 T 29-03-2018 IPR011004 Trimeric LpxA-like CB4_RS01210 e4a1060e0a9ffac221182e7df2e6acc1 219 PIRSF PIRSF000441 1 218 2.5E-85 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CB4_RS01210 e4a1060e0a9ffac221182e7df2e6acc1 219 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 5.0E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS01210 e4a1060e0a9ffac221182e7df2e6acc1 219 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 108 1.3E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS01210 e4a1060e0a9ffac221182e7df2e6acc1 219 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 165 3.2E-78 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CB4_RS14000 0784752b4cf6cb061374084bb0b70605 214 Gene3D G3DSA:3.40.50.1390 1 157 4.1E-34 T 29-03-2018 CB4_RS14000 0784752b4cf6cb061374084bb0b70605 214 SMART SM00857 3 149 6.3E-36 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS14000 0784752b4cf6cb061374084bb0b70605 214 SUPERFAMILY SSF53041 1 149 1.57E-27 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS14000 0784752b4cf6cb061374084bb0b70605 214 Pfam PF00239 Resolvase, N terminal domain 3 147 1.9E-29 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS04825 da7241747950806d167be25f2fddb5b3 381 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 19 227 1.9E-90 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CB4_RS04825 da7241747950806d167be25f2fddb5b3 381 SUPERFAMILY SSF52402 248 373 4.1E-15 T 29-03-2018 CB4_RS04825 da7241747950806d167be25f2fddb5b3 381 Pfam PF00582 Universal stress protein family 247 367 2.9E-8 T 29-03-2018 IPR006016 UspA GO:0006950 CB4_RS04825 da7241747950806d167be25f2fddb5b3 381 Gene3D G3DSA:3.40.50.620 224 373 7.9E-15 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS04825 da7241747950806d167be25f2fddb5b3 381 Gene3D G3DSA:3.40.50.300 18 148 4.1E-21 T 29-03-2018 CB4_RS04825 da7241747950806d167be25f2fddb5b3 381 SUPERFAMILY SSF52540 24 131 3.47E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03225 75519a700d3a6c811609c554b4cdb998 339 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 3.8E-96 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS03225 75519a700d3a6c811609c554b4cdb998 339 SUPERFAMILY SSF51735 2 332 9.84E-99 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS03225 75519a700d3a6c811609c554b4cdb998 339 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 319 1.0E-150 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CB4_RS03225 75519a700d3a6c811609c554b4cdb998 339 Gene3D G3DSA:3.40.50.720 2 183 1.1E-38 T 29-03-2018 CB4_RS03225 75519a700d3a6c811609c554b4cdb998 339 Gene3D G3DSA:3.90.25.10 184 335 5.7E-51 T 29-03-2018 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 SUPERFAMILY SSF54849 136 203 8.47E-28 T 29-03-2018 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 3.1E-261 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.0E-101 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 SUPERFAMILY SSF52029 183 374 1.24E-84 T 29-03-2018 IPR027409 GroEL-like apical domain CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 Gene3D G3DSA:1.10.560.10 372 513 1.7E-25 T 29-03-2018 IPR027413 GroEL-like equatorial domain CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 Gene3D G3DSA:1.10.560.10 61 177 2.9E-28 T 29-03-2018 IPR027413 GroEL-like equatorial domain CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 Gene3D G3DSA:3.50.7.10 178 371 7.0E-99 T 29-03-2018 IPR027409 GroEL-like apical domain CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 Hamap MF_00600 60 kDa chaperonin [groL]. 1 541 43.023 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 PRINTS PR00298 60kDa chaperonin signature 82 109 6.8E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 PRINTS PR00298 60kDa chaperonin signature 26 52 6.8E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 PRINTS PR00298 60kDa chaperonin signature 266 289 6.8E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 PRINTS PR00298 60kDa chaperonin signature 348 373 6.8E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 PRINTS PR00298 60kDa chaperonin signature 396 417 6.8E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 SUPERFAMILY SSF48592 6 133 1.22E-79 T 29-03-2018 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 SUPERFAMILY SSF48592 404 518 1.22E-79 T 29-03-2018 CB4_RS20435 5521bd0c8b7b487f3aff4d5a59dddc06 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CB4_RS01275 d4cff2e818b5f18130275f98b48784d5 249 SUPERFAMILY SSF52540 1 236 1.14E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01275 d4cff2e818b5f18130275f98b48784d5 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS01275 d4cff2e818b5f18130275f98b48784d5 249 Pfam PF00005 ABC transporter 17 174 4.0E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS01275 d4cff2e818b5f18130275f98b48784d5 249 SMART SM00382 26 230 1.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS01275 d4cff2e818b5f18130275f98b48784d5 249 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 2 249 9.4E-127 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CB4_RS01275 d4cff2e818b5f18130275f98b48784d5 249 Gene3D G3DSA:3.40.50.300 1 247 3.4E-66 T 29-03-2018 CB4_RS13690 8d2cada8171a5088645014192adaa21c 66 Gene3D G3DSA:1.10.3100.10 1 65 5.4E-16 T 29-03-2018 IPR027910 YdiL-like domain CB4_RS13690 8d2cada8171a5088645014192adaa21c 66 Pfam PF01381 Helix-turn-helix 5 59 8.2E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS13690 8d2cada8171a5088645014192adaa21c 66 SMART SM00530 4 59 3.9E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS13690 8d2cada8171a5088645014192adaa21c 66 SUPERFAMILY SSF47413 2 63 8.58E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS08320 6be4f796f91edddbc5bb32b673828360 256 SMART SM00062 33 256 1.9E-69 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CB4_RS08320 6be4f796f91edddbc5bb32b673828360 256 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 255 9.2E-68 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CB4_RS08320 6be4f796f91edddbc5bb32b673828360 256 SMART SM00079 33 256 5.1E-4 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CB4_RS08320 6be4f796f91edddbc5bb32b673828360 256 Gene3D G3DSA:3.40.190.10 27 178 1.7E-43 T 29-03-2018 CB4_RS08320 6be4f796f91edddbc5bb32b673828360 256 SUPERFAMILY SSF53850 1 255 1.86E-70 T 29-03-2018 CB4_RS08320 6be4f796f91edddbc5bb32b673828360 256 Gene3D G3DSA:3.40.190.10 179 254 1.6E-18 T 29-03-2018 CB4_RS12970 be67793c86b2503ad788dacab1351343 184 SUPERFAMILY SSF47413 3 70 4.56E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS12970 be67793c86b2503ad788dacab1351343 184 SUPERFAMILY SSF51182 59 183 3.57E-25 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS12970 be67793c86b2503ad788dacab1351343 184 Gene3D G3DSA:2.60.120.10 91 184 3.1E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS12970 be67793c86b2503ad788dacab1351343 184 SMART SM00530 11 66 2.4E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS12970 be67793c86b2503ad788dacab1351343 184 Pfam PF07883 Cupin domain 112 178 4.4E-12 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CB4_RS12970 be67793c86b2503ad788dacab1351343 184 Gene3D G3DSA:1.10.260.40 2 73 3.2E-16 T 29-03-2018 CB4_RS12970 be67793c86b2503ad788dacab1351343 184 Pfam PF01381 Helix-turn-helix 13 64 7.8E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 Gene3D G3DSA:3.30.70.260 451 526 2.4E-19 T 29-03-2018 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 528 6.6E-213 T 29-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 Gene3D G3DSA:3.40.50.720 1 107 6.3E-34 T 29-03-2018 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 Gene3D G3DSA:3.30.1330.90 317 450 3.6E-35 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 SUPERFAMILY SSF55021 445 526 1.55E-19 T 29-03-2018 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 SUPERFAMILY SSF51735 101 282 8.78E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 313 3.2E-34 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 Gene3D G3DSA:3.40.50.720 108 283 1.2E-59 T 29-03-2018 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 SUPERFAMILY SSF52283 1 135 3.4E-35 T 29-03-2018 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 SUPERFAMILY SSF143548 319 450 2.14E-34 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 1.9E-64 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 Pfam PF01842 ACT domain 455 518 1.1E-11 T 29-03-2018 IPR002912 ACT domain CB4_RS15890 2c588cbfd874a9c1e1368b79dd3a260e 528 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 192 214 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CB4_RS16735 1fd0ceb9889cdc2a8f1fb2119743ce93 310 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS16735 1fd0ceb9889cdc2a8f1fb2119743ce93 310 SMART SM00382 31 211 7.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS16735 1fd0ceb9889cdc2a8f1fb2119743ce93 310 SUPERFAMILY SSF52540 7 230 8.2E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS16735 1fd0ceb9889cdc2a8f1fb2119743ce93 310 Gene3D G3DSA:3.40.50.300 4 242 7.5E-63 T 29-03-2018 CB4_RS16735 1fd0ceb9889cdc2a8f1fb2119743ce93 310 Pfam PF00005 ABC transporter 23 163 1.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS19235 34a392ce9f32607bbdd53be4267924c4 127 SMART SM00345 14 73 5.2E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS19235 34a392ce9f32607bbdd53be4267924c4 127 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 2.9E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS19235 34a392ce9f32607bbdd53be4267924c4 127 Gene3D G3DSA:1.10.10.10 1 75 1.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19235 34a392ce9f32607bbdd53be4267924c4 127 SUPERFAMILY SSF46785 3 76 2.99E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14535 63adbca5bea5b12f63a7f2290b511192 71 PRINTS PR00352 3Fe-4S ferredoxin signature 6 17 1.1E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CB4_RS14535 63adbca5bea5b12f63a7f2290b511192 71 PRINTS PR00352 3Fe-4S ferredoxin signature 17 27 1.1E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CB4_RS14535 63adbca5bea5b12f63a7f2290b511192 71 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 1.1E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CB4_RS14535 63adbca5bea5b12f63a7f2290b511192 71 Gene3D G3DSA:3.30.70.20 18 69 1.5E-5 T 29-03-2018 CB4_RS14535 63adbca5bea5b12f63a7f2290b511192 71 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 6 69 1.2E-16 T 29-03-2018 CB4_RS14535 63adbca5bea5b12f63a7f2290b511192 71 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 11 22 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS14535 63adbca5bea5b12f63a7f2290b511192 71 SUPERFAMILY SSF54862 3 70 2.18E-12 T 29-03-2018 CB4_RS14535 63adbca5bea5b12f63a7f2290b511192 71 Gene3D G3DSA:3.30.70.20 1 17 3.2E-4 T 29-03-2018 CB4_RS17920 31bdb87f805b98c77645c7ff44c9986a 526 SUPERFAMILY SSF68923 12 210 3.66E-85 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CB4_RS17920 31bdb87f805b98c77645c7ff44c9986a 526 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 11 525 58.32 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CB4_RS17920 31bdb87f805b98c77645c7ff44c9986a 526 Pfam PF01293 Phosphoenolpyruvate carboxykinase 17 478 9.6E-233 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CB4_RS17920 31bdb87f805b98c77645c7ff44c9986a 526 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 248 263 - T 29-03-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CB4_RS17920 31bdb87f805b98c77645c7ff44c9986a 526 Gene3D G3DSA:3.90.228.20 211 290 3.4E-30 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CB4_RS17920 31bdb87f805b98c77645c7ff44c9986a 526 Gene3D G3DSA:3.90.228.20 291 523 8.8E-102 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CB4_RS17920 31bdb87f805b98c77645c7ff44c9986a 526 PIRSF PIRSF006294 1 525 4.4E-253 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CB4_RS17920 31bdb87f805b98c77645c7ff44c9986a 526 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 4 523 9.5E-249 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CB4_RS17920 31bdb87f805b98c77645c7ff44c9986a 526 SUPERFAMILY SSF53795 211 524 2.98E-142 T 29-03-2018 CB4_RS17920 31bdb87f805b98c77645c7ff44c9986a 526 Gene3D G3DSA:3.40.449.10 18 210 1.3E-80 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CB4_RS03230 5eeb8c6e0f29de9fea99047cbdf5e3d3 282 Gene3D G3DSA:3.40.50.720 1 197 6.0E-39 T 29-03-2018 CB4_RS03230 5eeb8c6e0f29de9fea99047cbdf5e3d3 282 Gene3D G3DSA:3.90.25.10 198 266 7.7E-27 T 29-03-2018 CB4_RS03230 5eeb8c6e0f29de9fea99047cbdf5e3d3 282 Pfam PF04321 RmlD substrate binding domain 3 280 6.3E-110 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CB4_RS03230 5eeb8c6e0f29de9fea99047cbdf5e3d3 282 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 280 1.5E-106 T 29-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CB4_RS03230 5eeb8c6e0f29de9fea99047cbdf5e3d3 282 SUPERFAMILY SSF51735 1 279 3.88E-97 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS14285 d81bcf12ea66d169757a10ae815d8a0f 139 SUPERFAMILY SSF158442 11 132 1.09E-28 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CB4_RS14285 d81bcf12ea66d169757a10ae815d8a0f 139 PIRSF PIRSF036659 1 138 9.3E-54 T 29-03-2018 IPR012187 Disulphide bond formation protein BdbC CB4_RS14285 d81bcf12ea66d169757a10ae815d8a0f 139 Pfam PF02600 Disulfide bond formation protein DsbB 12 114 1.4E-9 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CB4_RS14285 d81bcf12ea66d169757a10ae815d8a0f 139 Gene3D G3DSA:1.20.1550.10 4 134 4.8E-22 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CB4_RS14285 d81bcf12ea66d169757a10ae815d8a0f 139 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 3 138 23.337 T 29-03-2018 IPR012187 Disulphide bond formation protein BdbC CB4_RS15155 b6498c909c0817027209fd02749c764f 149 SUPERFAMILY SSF54919 1 148 1.83E-61 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS15155 b6498c909c0817027209fd02749c764f 149 SMART SM00562 3 140 1.6E-88 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS15155 b6498c909c0817027209fd02749c764f 149 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 29-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS15155 b6498c909c0817027209fd02749c764f 149 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 36.359 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS15155 b6498c909c0817027209fd02749c764f 149 Gene3D G3DSA:3.30.70.141 1 149 2.7E-58 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS15155 b6498c909c0817027209fd02749c764f 149 Pfam PF00334 Nucleoside diphosphate kinase 4 137 4.1E-58 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS15155 b6498c909c0817027209fd02749c764f 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 4.2E-51 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS15155 b6498c909c0817027209fd02749c764f 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 4.2E-51 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS15155 b6498c909c0817027209fd02749c764f 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 4.2E-51 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS15155 b6498c909c0817027209fd02749c764f 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 4.2E-51 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS15155 b6498c909c0817027209fd02749c764f 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 4.2E-51 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS14040 db232f84d40aba7962f2f0a688977799 412 Gene3D G3DSA:1.10.3860.10 2 403 4.1E-78 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS14040 db232f84d40aba7962f2f0a688977799 412 PRINTS PR00173 Glutamate-aspartate symporter signature 183 202 1.7E-14 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS14040 db232f84d40aba7962f2f0a688977799 412 PRINTS PR00173 Glutamate-aspartate symporter signature 320 339 1.7E-14 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS14040 db232f84d40aba7962f2f0a688977799 412 PRINTS PR00173 Glutamate-aspartate symporter signature 11 31 1.7E-14 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS14040 db232f84d40aba7962f2f0a688977799 412 PRINTS PR00173 Glutamate-aspartate symporter signature 218 237 1.7E-14 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS14040 db232f84d40aba7962f2f0a688977799 412 PRINTS PR00173 Glutamate-aspartate symporter signature 347 367 1.7E-14 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS14040 db232f84d40aba7962f2f0a688977799 412 PRINTS PR00173 Glutamate-aspartate symporter signature 285 311 1.7E-14 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS14040 db232f84d40aba7962f2f0a688977799 412 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 1 402 35.983 T 29-03-2018 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 CB4_RS14040 db232f84d40aba7962f2f0a688977799 412 Pfam PF00375 Sodium:dicarboxylate symporter family 13 393 2.9E-66 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS14040 db232f84d40aba7962f2f0a688977799 412 SUPERFAMILY SSF118215 13 395 2.48E-96 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 Gene3D G3DSA:1.10.287.950 425 670 3.4E-56 T 29-03-2018 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 Pfam PF02743 Cache domain 44 270 1.0E-22 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 Gene3D G3DSA:1.10.287.950 338 424 8.8E-9 T 29-03-2018 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 436 615 4.4E-49 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 Gene3D G3DSA:3.30.450.20 59 164 2.6E-8 T 29-03-2018 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 SMART SM00283 391 666 4.8E-88 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 SMART SM00304 309 362 9.7E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 SUPERFAMILY SSF58104 334 364 5.75E-76 T 29-03-2018 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 SUPERFAMILY SSF58104 397 666 5.75E-76 T 29-03-2018 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 Pfam PF00672 HAMP domain 312 359 3.4E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18075 eec9399424c5560a74094827dc2214fe 671 Gene3D G3DSA:3.30.450.20 165 286 2.1E-22 T 29-03-2018 CB4_RS10835 0b018affc0e5fc40cfba1a74c68fd93a 158 SUPERFAMILY SSF46689 9 40 1.5E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS10835 0b018affc0e5fc40cfba1a74c68fd93a 158 Gene3D G3DSA:1.10.357.10 36 158 8.7E-17 T 29-03-2018 CB4_RS10835 0b018affc0e5fc40cfba1a74c68fd93a 158 Gene3D G3DSA:1.10.10.60 6 35 2.5E-6 T 29-03-2018 CB4_RS10835 0b018affc0e5fc40cfba1a74c68fd93a 158 SUPERFAMILY SSF48498 49 157 5.4E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS10835 0b018affc0e5fc40cfba1a74c68fd93a 158 Pfam PF16859 Bacterial transcriptional repressor C-terminal 45 154 1.7E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 Gene3D G3DSA:1.10.150.20 119 171 0.05 T 29-03-2018 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 Pfam PF07499 RuvA, C-terminal domain 163 207 3.4E-12 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 SUPERFAMILY SSF50249 1 62 1.2E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 209 30.591 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 SMART SM00278 72 91 1.3 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 SMART SM00278 107 126 0.031 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 207 3.1E-55 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 Pfam PF01330 RuvA N terminal domain 1 61 2.3E-20 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 Gene3D G3DSA:1.10.8.10 172 208 1.6E-10 T 29-03-2018 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 SUPERFAMILY SSF46929 163 208 4.05E-8 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 Gene3D G3DSA:2.40.50.140 1 65 8.8E-23 T 29-03-2018 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 Gene3D G3DSA:1.10.150.20 66 118 4.2E-13 T 29-03-2018 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 Pfam PF14520 Helix-hairpin-helix domain 71 129 9.3E-20 T 29-03-2018 CB4_RS05930 e7175e903be0600f1066f6246ae77345 211 SUPERFAMILY SSF47781 64 133 5.56E-22 T 29-03-2018 IPR010994 RuvA domain 2-like CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 PIRSF PIRSF006809 4 419 3.7E-153 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 SUPERFAMILY SSF52540 201 363 4.84E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 11 360 1.4E-144 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 Gene3D G3DSA:3.40.50.300 184 234 6.9E-14 T 29-03-2018 CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 Pfam PF01926 50S ribosome-binding GTPase 203 322 2.2E-18 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 Pfam PF13167 GTP-binding GTPase N-terminal 30 116 3.2E-33 T 29-03-2018 IPR025121 GTPase HflX, N-terminal CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 204 224 3.2E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 271 289 3.2E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 Pfam PF16360 GTP-binding GTPase Middle Region 118 196 2.2E-31 T 29-03-2018 IPR032305 GTP-binding protein, middle domain CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 Hamap MF_00900 GTPase HflX [hflX]. 31 389 48.246 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 Gene3D G3DSA:1.20.5.170 25 183 0.0011 T 29-03-2018 CB4_RS14100 9a62b0541ead47c0d38f31d19bed1321 421 Gene3D G3DSA:3.40.50.300 235 388 3.9E-17 T 29-03-2018 CB4_RS02310 c927725c657e5651912c27bb9dc6e617 387 Pfam PF13458 Periplasmic binding protein 44 381 3.4E-70 T 29-03-2018 IPR028081 Leucine-binding protein domain CB4_RS02310 c927725c657e5651912c27bb9dc6e617 387 Gene3D G3DSA:3.40.50.2300 37 173 1.1E-25 T 29-03-2018 CB4_RS02310 c927725c657e5651912c27bb9dc6e617 387 SUPERFAMILY SSF53822 45 386 1.29E-86 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS02310 c927725c657e5651912c27bb9dc6e617 387 Gene3D G3DSA:3.40.50.2300 174 327 4.0E-43 T 29-03-2018 CB4_RS08085 0e058ce8a72a0232a2d4ed9032b8b912 326 Pfam PF03060 Nitronate monooxygenase 3 73 1.4E-18 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CB4_RS08085 0e058ce8a72a0232a2d4ed9032b8b912 326 Pfam PF03060 Nitronate monooxygenase 77 305 6.4E-50 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CB4_RS08085 0e058ce8a72a0232a2d4ed9032b8b912 326 SUPERFAMILY SSF51412 1 315 3.51E-64 T 29-03-2018 CB4_RS08085 0e058ce8a72a0232a2d4ed9032b8b912 326 Gene3D G3DSA:3.20.20.70 1 318 1.6E-56 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS15105 27411c99a3dc4a71f85c34d57b23dd6d 401 Gene3D G3DSA:3.40.50.1100 201 399 5.1E-39 T 29-03-2018 CB4_RS15105 27411c99a3dc4a71f85c34d57b23dd6d 401 SUPERFAMILY SSF53686 10 392 2.49E-147 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS15105 27411c99a3dc4a71f85c34d57b23dd6d 401 Gene3D G3DSA:3.40.50.1100 74 200 2.3E-37 T 29-03-2018 CB4_RS15105 27411c99a3dc4a71f85c34d57b23dd6d 401 Gene3D G3DSA:3.40.50.1100 13 73 1.5E-8 T 29-03-2018 CB4_RS15105 27411c99a3dc4a71f85c34d57b23dd6d 401 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 11 393 8.1E-195 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS15105 27411c99a3dc4a71f85c34d57b23dd6d 401 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 381 7.7E-48 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS15105 27411c99a3dc4a71f85c34d57b23dd6d 401 PIRSF PIRSF001413 1 400 7.4E-169 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS15105 27411c99a3dc4a71f85c34d57b23dd6d 401 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 85 99 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS15105 27411c99a3dc4a71f85c34d57b23dd6d 401 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 6 395 53.016 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS14145 9b251b707b2f09560741dae297a15661 464 SUPERFAMILY SSF111369 224 384 9.15E-8 T 29-03-2018 CB4_RS14145 9b251b707b2f09560741dae297a15661 464 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 380 3.3E-12 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CB4_RS14145 9b251b707b2f09560741dae297a15661 464 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 211 460 3.8E-37 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CB4_RS14145 9b251b707b2f09560741dae297a15661 464 Gene3D G3DSA:1.10.287.470 159 217 2.1E-11 T 29-03-2018 CB4_RS14145 9b251b707b2f09560741dae297a15661 464 Gene3D G3DSA:2.40.50.100 64 136 1.4E-14 T 29-03-2018 CB4_RS14145 9b251b707b2f09560741dae297a15661 464 Gene3D G3DSA:1.20.1600.10 226 379 2.0E-10 T 29-03-2018 CB4_RS14145 9b251b707b2f09560741dae297a15661 464 SUPERFAMILY SSF111369 56 159 2.48E-10 T 29-03-2018 CB4_RS13775 c66625812f5e4f4d1c69fc82ee338c0e 131 TIGRFAM TIGR00494 crcB: protein CrcB 5 118 1.4E-27 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CB4_RS13775 c66625812f5e4f4d1c69fc82ee338c0e 131 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 19.946 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CB4_RS13775 c66625812f5e4f4d1c69fc82ee338c0e 131 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 115 1.1E-24 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 Gene3D G3DSA:3.30.470.20 209 443 3.4E-97 T 29-03-2018 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 SUPERFAMILY SSF56059 82 351 1.17E-69 T 29-03-2018 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 SMART SM00878 335 440 1.8E-51 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 Pfam PF02785 Biotin carboxylase C-terminal domain 335 440 3.3E-36 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 SUPERFAMILY SSF51246 330 442 7.85E-39 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 1.1E-42 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 SUPERFAMILY SSF52440 1 112 6.04E-45 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 321 1.7E-76 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 Gene3D G3DSA:3.30.1490.20 123 208 1.7E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS08180 32b9d19856194f280abb4154ff692fcb 448 Gene3D G3DSA:3.40.50.20 1 122 9.5E-51 T 29-03-2018 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 Gene3D G3DSA:3.40.50.300 2 74 2.9E-11 T 29-03-2018 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 SUPERFAMILY SSF50447 206 303 2.55E-32 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 Pfam PF03144 Elongation factor Tu domain 2 226 295 3.2E-18 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 SUPERFAMILY SSF52540 6 220 3.07E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 1.9E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 4.2E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.2E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.2E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.2E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.2E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 5.2E-34 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.063 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 Gene3D G3DSA:2.40.30.10 302 394 6.5E-32 T 29-03-2018 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 Gene3D G3DSA:2.40.30.10 207 301 1.8E-31 T 29-03-2018 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 SUPERFAMILY SSF50465 304 394 1.76E-35 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 Gene3D G3DSA:3.40.50.300 75 204 1.5E-31 T 29-03-2018 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 3.0E-59 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01100 81b1d66e7e46381612a84cc8b6f6fa27 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 2.3E-227 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS01555 5b1f84bec5203ab4eca99e495193e1cd 83 Gene3D G3DSA:2.10.260.10 1 48 1.0E-19 T 29-03-2018 CB4_RS01555 5b1f84bec5203ab4eca99e495193e1cd 83 SUPERFAMILY SSF89447 1 53 6.28E-17 T 29-03-2018 CB4_RS01555 5b1f84bec5203ab4eca99e495193e1cd 83 SMART SM00966 8 51 1.7E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS01555 5b1f84bec5203ab4eca99e495193e1cd 83 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 6.2E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS01555 5b1f84bec5203ab4eca99e495193e1cd 83 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 4.1E-11 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS08765 df86404007964e624808c1c23002a6d2 82 Gene3D G3DSA:1.10.3100.10 1 81 3.0E-11 T 29-03-2018 IPR027910 YdiL-like domain CB4_RS08765 df86404007964e624808c1c23002a6d2 82 SUPERFAMILY SSF47413 4 66 2.11E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS08765 df86404007964e624808c1c23002a6d2 82 Pfam PF01381 Helix-turn-helix 7 61 3.3E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS08765 df86404007964e624808c1c23002a6d2 82 SMART SM00530 5 61 3.9E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS12815 32fcc6e9d88e8dc4cc0245d5882b5627 171 Gene3D G3DSA:1.10.1660.10 7 66 2.4E-24 T 29-03-2018 CB4_RS12815 32fcc6e9d88e8dc4cc0245d5882b5627 171 Gene3D G3DSA:1.10.1660.10 67 144 4.2E-10 T 29-03-2018 CB4_RS12815 32fcc6e9d88e8dc4cc0245d5882b5627 171 SUPERFAMILY SSF46955 11 117 2.97E-27 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS12815 32fcc6e9d88e8dc4cc0245d5882b5627 171 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 8.4E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS12815 32fcc6e9d88e8dc4cc0245d5882b5627 171 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 8.4E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS12815 32fcc6e9d88e8dc4cc0245d5882b5627 171 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 8.4E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS12815 32fcc6e9d88e8dc4cc0245d5882b5627 171 Pfam PF13411 MerR HTH family regulatory protein 13 78 4.1E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS12815 32fcc6e9d88e8dc4cc0245d5882b5627 171 SMART SM00422 11 80 1.5E-28 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS13855 e6193b245363beec4237ca9d1d813534 274 Gene3D G3DSA:1.10.600.10 7 265 8.0E-45 T 29-03-2018 IPR008949 Isoprenoid synthase domain CB4_RS13855 e6193b245363beec4237ca9d1d813534 274 Pfam PF00494 Squalene/phytoene synthase 17 206 6.4E-18 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CB4_RS13855 e6193b245363beec4237ca9d1d813534 274 SUPERFAMILY SSF48576 11 262 4.46E-40 T 29-03-2018 IPR008949 Isoprenoid synthase domain CB4_RS06120 9d960a31e5e0f663eaf2c6136fc1f12d 340 Gene3D G3DSA:3.30.160.60 306 340 9.0E-13 T 29-03-2018 CB4_RS06120 9d960a31e5e0f663eaf2c6136fc1f12d 340 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 4 340 33.95 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CB4_RS06120 9d960a31e5e0f663eaf2c6136fc1f12d 340 Gene3D G3DSA:3.30.160.60 73 102 1.3E-4 T 29-03-2018 CB4_RS06120 9d960a31e5e0f663eaf2c6136fc1f12d 340 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 4 333 8.3E-83 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CB4_RS06120 9d960a31e5e0f663eaf2c6136fc1f12d 340 Pfam PF02618 YceG-like family 36 333 1.2E-86 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CB4_RS15720 37d36aa74d832b3046dfa03b19549a98 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 231 3.0E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS15720 37d36aa74d832b3046dfa03b19549a98 260 SUPERFAMILY SSF161098 53 236 3.27E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS15720 37d36aa74d832b3046dfa03b19549a98 260 Gene3D G3DSA:1.10.3720.10 13 246 5.2E-19 T 29-03-2018 CB4_RS15930 08679b1cb38bedf8976bc9ff8de31487 130 PIRSF PIRSF003230 1 130 8.6E-22 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CB4_RS15930 08679b1cb38bedf8976bc9ff8de31487 130 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 116 3.6E-22 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CB4_RS15930 08679b1cb38bedf8976bc9ff8de31487 130 Gene3D G3DSA:3.10.129.10 2 130 7.7E-33 T 29-03-2018 CB4_RS15930 08679b1cb38bedf8976bc9ff8de31487 130 Pfam PF13279 Thioesterase-like superfamily 9 127 9.9E-17 T 29-03-2018 CB4_RS15930 08679b1cb38bedf8976bc9ff8de31487 130 SUPERFAMILY SSF54637 4 129 1.38E-35 T 29-03-2018 IPR029069 HotDog domain CB4_RS00830 b4aaa850f7376af88cbcfee1df9a3908 122 SUPERFAMILY SSF46946 2 121 2.09E-46 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CB4_RS00830 b4aaa850f7376af88cbcfee1df9a3908 122 Pfam PF00416 Ribosomal protein S13/S18 3 109 3.2E-34 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00830 b4aaa850f7376af88cbcfee1df9a3908 122 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00830 b4aaa850f7376af88cbcfee1df9a3908 122 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 28.613 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00830 b4aaa850f7376af88cbcfee1df9a3908 122 Gene3D G3DSA:1.10.8.50 1 67 6.6E-25 T 29-03-2018 CB4_RS00830 b4aaa850f7376af88cbcfee1df9a3908 122 Gene3D G3DSA:4.10.910.10 87 122 7.8E-27 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00830 b4aaa850f7376af88cbcfee1df9a3908 122 PIRSF PIRSF002134 1 122 1.4E-43 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00830 b4aaa850f7376af88cbcfee1df9a3908 122 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 9.6E-55 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00830 b4aaa850f7376af88cbcfee1df9a3908 122 Gene3D G3DSA:4.10.910.10 68 86 3.1E-16 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PIRSF PIRSF000350 1 470 8.1E-86 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 SUPERFAMILY SSF51905 1 344 8.89E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 Gene3D G3DSA:3.30.390.30 366 473 3.6E-40 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 Gene3D G3DSA:3.50.50.60 183 365 1.6E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 472 1.3E-174 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 3.1E-35 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 3.1E-35 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.1E-35 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 3.1E-35 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 3.1E-35 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 6.6E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 SUPERFAMILY SSF55424 350 472 1.37E-40 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 7.1E-36 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 Gene3D G3DSA:3.50.50.60 1 178 4.0E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 6.5E-70 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 6.5E-70 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 6.5E-70 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 155 6.5E-70 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 6.5E-70 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 6.5E-70 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 182 207 6.5E-70 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 6.5E-70 T 29-03-2018 CB4_RS16385 8d0ed869b749055cee7181a34ca9941f 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.5E-70 T 29-03-2018 CB4_RS19600 58e74ce6b4b2d99da51373f4a67720b4 209 Gene3D G3DSA:1.20.5.40 121 137 1.8E-14 T 29-03-2018 CB4_RS19600 58e74ce6b4b2d99da51373f4a67720b4 209 SUPERFAMILY SSF53041 4 150 2.88E-33 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS19600 58e74ce6b4b2d99da51373f4a67720b4 209 Gene3D G3DSA:1.10.10.60 138 205 8.3E-5 T 29-03-2018 CB4_RS19600 58e74ce6b4b2d99da51373f4a67720b4 209 Gene3D G3DSA:3.40.50.1390 1 120 1.8E-27 T 29-03-2018 CB4_RS19600 58e74ce6b4b2d99da51373f4a67720b4 209 SMART SM00857 5 150 4.2E-30 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS19600 58e74ce6b4b2d99da51373f4a67720b4 209 Pfam PF00239 Resolvase, N terminal domain 6 150 1.6E-25 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS00620 93d615549ab8120c026b704df6814b61 272 Hamap MF_01499 Diadenylate cyclase [dacA]. 8 254 34.233 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CB4_RS00620 93d615549ab8120c026b704df6814b61 272 SUPERFAMILY SSF143597 40 240 1.57E-70 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CB4_RS00620 93d615549ab8120c026b704df6814b61 272 PIRSF PIRSF004793 4 268 9.5E-92 T 29-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CB4_RS00620 93d615549ab8120c026b704df6814b61 272 Gene3D G3DSA:3.40.1700.10 111 238 1.2E-39 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CB4_RS00620 93d615549ab8120c026b704df6814b61 272 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 235 1.2E-43 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CB4_RS00620 93d615549ab8120c026b704df6814b61 272 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 7 254 1.6E-89 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CB4_RS02155 3920aa53a163d699b06fa7ab6c4813b4 292 Gene3D G3DSA:3.30.565.40 73 188 6.7E-11 T 29-03-2018 CB4_RS02155 3920aa53a163d699b06fa7ab6c4813b4 292 Pfam PF11738 Protein of unknown function (DUF3298) 193 278 2.4E-19 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CB4_RS02155 3920aa53a163d699b06fa7ab6c4813b4 292 Gene3D G3DSA:3.90.640.20 189 292 1.8E-25 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CB4_RS12860 26e4978c4f3a640c4936bbced3d2393f 222 PIRSF PIRSF036692 1 221 3.1E-76 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CB4_RS12860 26e4978c4f3a640c4936bbced3d2393f 222 Pfam PF03315 Serine dehydratase beta chain 5 87 3.1E-13 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CB4_RS12860 26e4978c4f3a640c4936bbced3d2393f 222 Gene3D G3DSA:3.30.70.260 137 215 3.3E-7 T 29-03-2018 CB4_RS12860 26e4978c4f3a640c4936bbced3d2393f 222 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 204 1.4E-60 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CB4_RS12860 26e4978c4f3a640c4936bbced3d2393f 222 SUPERFAMILY SSF143548 19 135 1.44E-26 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CB4_RS12860 26e4978c4f3a640c4936bbced3d2393f 222 Gene3D G3DSA:3.30.1330.90 13 136 4.9E-21 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CB4_RS12860 26e4978c4f3a640c4936bbced3d2393f 222 SUPERFAMILY SSF55021 138 210 1.03E-11 T 29-03-2018 CB4_RS01140 6370731f05a6a4151cdc4f98937019f3 119 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 53 119 3.6E-31 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01140 6370731f05a6a4151cdc4f98937019f3 119 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 119 1.9E-48 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01140 6370731f05a6a4151cdc4f98937019f3 119 Gene3D G3DSA:1.20.5.710 1 48 5.4E-18 T 29-03-2018 CB4_RS01140 6370731f05a6a4151cdc4f98937019f3 119 SUPERFAMILY SSF54736 49 119 8.2E-25 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CB4_RS01140 6370731f05a6a4151cdc4f98937019f3 119 Gene3D G3DSA:3.30.1390.10 49 119 1.8E-30 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CB4_RS01140 6370731f05a6a4151cdc4f98937019f3 119 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 119 24.725 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01140 6370731f05a6a4151cdc4f98937019f3 119 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 48 8.1E-22 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01140 6370731f05a6a4151cdc4f98937019f3 119 SUPERFAMILY SSF48300 1 55 4.19E-16 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01140 6370731f05a6a4151cdc4f98937019f3 119 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 57 119 3.0E-21 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 Pfam PF00027 Cyclic nucleotide-binding domain 612 698 2.5E-21 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 SUPERFAMILY SSF52540 325 569 1.77E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 SUPERFAMILY SSF90123 6 319 7.98E-56 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 Gene3D G3DSA:2.60.120.10 580 709 2.9E-34 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 PRINTS PR00103 cAMP-dependent protein kinase signature 629 643 5.3E-8 T 29-03-2018 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 PRINTS PR00103 cAMP-dependent protein kinase signature 614 628 5.3E-8 T 29-03-2018 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 PRINTS PR00103 cAMP-dependent protein kinase signature 671 682 5.3E-8 T 29-03-2018 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 PRINTS PR00103 cAMP-dependent protein kinase signature 659 668 5.3E-8 T 29-03-2018 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 SMART SM00100 593 709 1.3E-23 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 Gene3D G3DSA:1.20.1560.10 2 317 1.6E-46 T 29-03-2018 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 Pfam PF00005 ABC transporter 349 498 6.9E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 661 678 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 Gene3D G3DSA:3.40.50.300 320 575 4.9E-77 T 29-03-2018 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 SMART SM00382 358 544 6.1E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 Pfam PF00664 ABC transporter transmembrane region 20 284 4.9E-27 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS19795 1eb2e0bffad8f92c9e6cb37525e6461e 709 SUPERFAMILY SSF51206 587 707 4.32E-33 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 Pfam PF00476 DNA polymerase family A 505 880 1.5E-160 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 SUPERFAMILY SSF47807 171 286 4.49E-31 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 Gene3D G3DSA:3.30.70.370 796 882 7.9E-27 T 29-03-2018 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 Gene3D G3DSA:1.10.150.20 185 263 1.5E-29 T 29-03-2018 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 Gene3D G3DSA:3.30.70.370 610 697 1.1E-17 T 29-03-2018 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 SMART SM00279 173 208 1.4E-17 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 Gene3D G3DSA:1.10.150.20 698 795 8.8E-37 T 29-03-2018 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 Gene3D G3DSA:3.30.420.10 300 496 5.0E-26 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 172 262 2.1E-32 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 169 5.1E-53 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 SMART SM00475 3 262 1.3E-137 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 SUPERFAMILY SSF88723 2 169 6.87E-53 T 29-03-2018 IPR029060 PIN domain-like CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 TIGRFAM TIGR00593 pola: DNA polymerase I 5 882 0.0 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 ProSitePatterns PS00447 DNA polymerase family A signature. 708 727 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 799 815 3.7E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 684 697 3.7E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 745 756 3.7E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 708 733 3.7E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 767 778 3.7E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 654 677 3.7E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 631 646 3.7E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 608 630 3.7E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 829 842 3.7E-83 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 SUPERFAMILY SSF53098 322 473 5.16E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 Gene3D G3DSA:1.20.1060.10 497 609 1.2E-31 T 29-03-2018 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 Gene3D G3DSA:3.40.50.1010 3 184 1.2E-65 T 29-03-2018 IPR029060 PIN domain-like CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 SMART SM00482 639 846 1.3E-122 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 SMART SM00474 305 472 3.8E-17 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CB4_RS18365 b237f7d2cd2fc008fd373c134c9bab8a 882 SUPERFAMILY SSF56672 477 882 8.01E-159 T 29-03-2018 CB4_RS17820 96857cc6f30462cf4ffbf51b4cc5a81b 457 Pfam PF00270 DEAD/DEAH box helicase 26 192 6.0E-50 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS17820 96857cc6f30462cf4ffbf51b4cc5a81b 457 SMART SM00487 21 218 1.2E-58 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS17820 96857cc6f30462cf4ffbf51b4cc5a81b 457 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CB4_RS17820 96857cc6f30462cf4ffbf51b4cc5a81b 457 Gene3D G3DSA:3.40.50.300 220 457 2.2E-48 T 29-03-2018 CB4_RS17820 96857cc6f30462cf4ffbf51b4cc5a81b 457 SUPERFAMILY SSF52540 70 351 3.14E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS17820 96857cc6f30462cf4ffbf51b4cc5a81b 457 Gene3D G3DSA:3.40.50.300 2 219 1.5E-59 T 29-03-2018 CB4_RS17820 96857cc6f30462cf4ffbf51b4cc5a81b 457 SMART SM00490 254 335 1.3E-34 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS17820 96857cc6f30462cf4ffbf51b4cc5a81b 457 Pfam PF00271 Helicase conserved C-terminal domain 226 335 8.2E-32 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 SUPERFAMILY SSF48371 298 366 2.3E-10 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 Gene3D G3DSA:1.25.40.70 268 345 3.5E-9 T 29-03-2018 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 Gene3D G3DSA:3.30.70.20 196 267 4.3E-8 T 29-03-2018 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 Pfam PF13484 4Fe-4S double cluster binding domain 188 250 1.6E-15 T 29-03-2018 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 2.8E-19 T 29-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 42.565 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 Pfam PF13646 HEAT repeats 300 365 1.1E-11 T 29-03-2018 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 SUPERFAMILY SSF54862 164 257 1.67E-14 T 29-03-2018 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 SMART SM00567 E-Z type HEAT repeats 298 327 5.2 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 SMART SM00567 E-Z type HEAT repeats 330 359 1.3E-4 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 Gene3D G3DSA:3.30.70.20 78 195 2.9E-4 T 29-03-2018 CB4_RS18930 deac1d5df6a47b9d6083c8780736c0d9 379 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 342 1.7E-123 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CB4_RS20275 533009bef8ea6ad9e0cc5bab23fcde54 759 Gene3D G3DSA:3.40.50.300 5 142 9.4E-29 T 29-03-2018 CB4_RS20275 533009bef8ea6ad9e0cc5bab23fcde54 759 Gene3D G3DSA:3.40.50.300 144 286 5.9E-37 T 29-03-2018 CB4_RS20275 533009bef8ea6ad9e0cc5bab23fcde54 759 SUPERFAMILY SSF52540 6 647 4.37E-188 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS20275 533009bef8ea6ad9e0cc5bab23fcde54 759 Gene3D G3DSA:3.40.50.300 287 389 1.4E-29 T 29-03-2018 CB4_RS20275 533009bef8ea6ad9e0cc5bab23fcde54 759 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 11 757 0.0 T 29-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CB4_RS20275 533009bef8ea6ad9e0cc5bab23fcde54 759 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 277 5.1E-84 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CB4_RS20275 533009bef8ea6ad9e0cc5bab23fcde54 759 Pfam PF13361 UvrD-like helicase C-terminal domain 282 618 2.3E-75 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CB4_RS20275 533009bef8ea6ad9e0cc5bab23fcde54 759 Gene3D G3DSA:3.40.50.300 427 663 6.2E-50 T 29-03-2018 CB4_RS09175 887e585da1c5cf79bc66b0fab9ba2f89 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 7.1E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CB4_RS09175 887e585da1c5cf79bc66b0fab9ba2f89 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 7.1E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CB4_RS09175 887e585da1c5cf79bc66b0fab9ba2f89 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 7.1E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CB4_RS09175 887e585da1c5cf79bc66b0fab9ba2f89 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 2.4E-32 T 29-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 CB4_RS09175 887e585da1c5cf79bc66b0fab9ba2f89 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.8E-30 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CB4_RS09175 887e585da1c5cf79bc66b0fab9ba2f89 89 PIRSF PIRSF004669 1 89 3.9E-33 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 Gene3D G3DSA:3.40.1830.10 5 175 1.6E-62 T 29-03-2018 IPR035097 Peptidase M29, N-terminal CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 5.5E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 5.5E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 363 385 5.5E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 5.5E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 5.5E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 5.5E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 389 408 5.5E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 5.5E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 Pfam PF02073 Thermophilic metalloprotease (M29) 5 408 2.4E-177 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CB4_RS18660 60a6e5df210e042b305aeed52c05ebd0 411 SUPERFAMILY SSF144052 5 409 5.49E-147 T 29-03-2018 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 PIRSF PIRSF001553 1 292 3.3E-128 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 153 182 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 Pfam PF00549 CoA-ligase 152 269 4.3E-19 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 SUPERFAMILY SSF52210 124 287 8.77E-56 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 289 42.948 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 Pfam PF02629 CoA binding domain 6 100 2.5E-26 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 237 250 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 Gene3D G3DSA:3.40.50.720 1 120 5.2E-42 T 29-03-2018 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 PRINTS PR01798 Succinyl-CoA synthase signature 209 222 2.9E-41 T 29-03-2018 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 PRINTS PR01798 Succinyl-CoA synthase signature 83 100 2.9E-41 T 29-03-2018 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 PRINTS PR01798 Succinyl-CoA synthase signature 178 196 2.9E-41 T 29-03-2018 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 PRINTS PR01798 Succinyl-CoA synthase signature 241 258 2.9E-41 T 29-03-2018 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 Gene3D G3DSA:3.40.50.261 121 301 4.6E-58 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 289 2.4E-141 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 SUPERFAMILY SSF51735 1 123 1.49E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS09035 032bdbc7d2c2f0cf01349527572bbf13 302 SMART SM00881 4 101 8.3E-31 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 184 4.7E-40 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 SMART SM00304 213 265 1.1E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 Gene3D G3DSA:1.10.287.850 239 312 0.015 T 29-03-2018 CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 Gene3D G3DSA:1.10.287.950 313 528 1.7E-55 T 29-03-2018 CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 SMART SM00283 280 527 6.4E-79 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 Gene3D G3DSA:1.20.120.30 26 185 1.1E-18 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 495 8.6E-46 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 SUPERFAMILY SSF58104 233 528 3.4E-75 T 29-03-2018 CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 371 398 3.3E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 429 3.3E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS20725 a83442bcf1e5bd7c15351cd8db2ac1b6 528 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 3.3E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS15345 f3b59e2a3a24bf8b6ae60e32be3e0613 524 SMART SM00490 247 328 6.4E-21 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS15345 f3b59e2a3a24bf8b6ae60e32be3e0613 524 Gene3D G3DSA:3.40.50.300 204 485 2.5E-41 T 29-03-2018 CB4_RS15345 f3b59e2a3a24bf8b6ae60e32be3e0613 524 SUPERFAMILY SSF52540 26 339 2.67E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15345 f3b59e2a3a24bf8b6ae60e32be3e0613 524 Gene3D G3DSA:3.40.50.300 2 202 3.5E-33 T 29-03-2018 CB4_RS15345 f3b59e2a3a24bf8b6ae60e32be3e0613 524 Pfam PF00270 DEAD/DEAH box helicase 22 183 6.4E-21 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS15345 f3b59e2a3a24bf8b6ae60e32be3e0613 524 SMART SM00487 15 212 2.3E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS15345 f3b59e2a3a24bf8b6ae60e32be3e0613 524 Pfam PF00271 Helicase conserved C-terminal domain 227 327 3.4E-15 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS15345 f3b59e2a3a24bf8b6ae60e32be3e0613 524 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 358 2.7E-112 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CB4_RS15345 f3b59e2a3a24bf8b6ae60e32be3e0613 524 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 135 144 - T 29-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 Gene3D G3DSA:3.40.50.300 2 80 8.1E-8 T 29-03-2018 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 368 46.273 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 SUPERFAMILY SSF52540 5 306 3.94E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 PIRSF PIRSF006641 1 368 1.2E-163 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 SUPERFAMILY SSF81271 284 365 9.81E-36 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 9.8E-37 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 9.8E-37 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 9.8E-37 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 9.8E-37 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 Pfam PF06071 Protein of unknown function (DUF933) 284 367 3.4E-40 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 Gene3D G3DSA:1.10.150.300 110 200 1.3E-29 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 Pfam PF01926 50S ribosome-binding GTPase 5 121 4.0E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 368 4.5E-161 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CB4_RS01995 b56ca2bde14962fce0e5f5d60c39b504 368 Gene3D G3DSA:3.10.20.30 268 367 4.1E-47 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 Gene3D G3DSA:3.50.50.60 117 307 4.6E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 120 402 5.8E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 243 255 9.5E-46 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 309 325 9.5E-46 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 121 143 9.5E-46 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 347 368 9.5E-46 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 169 9.5E-46 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 258 282 9.5E-46 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 381 399 9.5E-46 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 175 185 9.5E-46 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 221 229 9.5E-46 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 SUPERFAMILY SSF51905 120 420 4.45E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 ProSitePatterns PS00195 Glutaredoxin active site. 7 23 - T 29-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 Gene3D G3DSA:3.40.30.10 2 78 1.5E-16 T 29-03-2018 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 Pfam PF00462 Glutaredoxin 5 63 6.1E-14 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 371 393 1.4E-21 T 29-03-2018 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 345 361 1.4E-21 T 29-03-2018 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 280 1.4E-21 T 29-03-2018 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 220 238 1.4E-21 T 29-03-2018 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 122 141 1.4E-21 T 29-03-2018 CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 SUPERFAMILY SSF52833 4 74 3.32E-15 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS17480 11ac6d986dc668ac4f9f11263d583d6f 429 Gene3D G3DSA:3.50.50.60 308 428 2.5E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS01090 9977a04b8569b339ecacb93388f62c19 217 Pfam PF01895 PhoU domain 120 204 1.7E-15 T 29-03-2018 IPR026022 PhoU domain CB4_RS01090 9977a04b8569b339ecacb93388f62c19 217 Pfam PF01895 PhoU domain 17 103 4.7E-16 T 29-03-2018 IPR026022 PhoU domain CB4_RS01090 9977a04b8569b339ecacb93388f62c19 217 PIRSF PIRSF003107 1 217 1.4E-49 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CB4_RS01090 9977a04b8569b339ecacb93388f62c19 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 212 5.2E-49 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CB4_RS01090 9977a04b8569b339ecacb93388f62c19 217 Gene3D G3DSA:1.20.58.220 112 217 5.5E-21 T 29-03-2018 CB4_RS01090 9977a04b8569b339ecacb93388f62c19 217 SUPERFAMILY SSF109755 7 215 3.35E-53 T 29-03-2018 CB4_RS01090 9977a04b8569b339ecacb93388f62c19 217 Gene3D G3DSA:1.20.58.220 1 111 1.5E-20 T 29-03-2018 CB4_RS08625 570ef80d4084491cd18f6e6742f204e2 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 23.072 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CB4_RS08625 570ef80d4084491cd18f6e6742f204e2 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 2.4E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CB4_RS08625 570ef80d4084491cd18f6e6742f204e2 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 55 76 0.001 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CB4_RS08625 570ef80d4084491cd18f6e6742f204e2 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 77 4.4E-34 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CB4_RS08625 570ef80d4084491cd18f6e6742f204e2 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CB4_RS08625 570ef80d4084491cd18f6e6742f204e2 77 SUPERFAMILY SSF47336 2 76 3.53E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CB4_RS08625 570ef80d4084491cd18f6e6742f204e2 77 Gene3D G3DSA:1.10.1200.10 1 77 5.5E-26 T 29-03-2018 CB4_RS07975 8536a0772647c2ea3817241c4dc9c397 82 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 11 49 1.0E-9 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CB4_RS07975 8536a0772647c2ea3817241c4dc9c397 82 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 11 66 8.3E-24 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CB4_RS07975 8536a0772647c2ea3817241c4dc9c397 82 Pfam PF02609 Exonuclease VII small subunit 11 61 4.4E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CB4_RS07975 8536a0772647c2ea3817241c4dc9c397 82 SUPERFAMILY SSF116842 3 73 1.83E-22 T 29-03-2018 CB4_RS07975 8536a0772647c2ea3817241c4dc9c397 82 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 10 70 15.61 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CB4_RS07975 8536a0772647c2ea3817241c4dc9c397 82 PIRSF PIRSF006488 1 75 1.6E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CB4_RS07975 8536a0772647c2ea3817241c4dc9c397 82 Gene3D G3DSA:1.10.287.1040 8 73 1.2E-24 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CB4_RS09490 31fd14d9f26bbac8ec0d23dab38bc2fd 388 Pfam PF10720 Protein of unknown function (DUF2515) 55 378 5.5E-123 T 29-03-2018 IPR019658 Protein of unknown function DUF2515 CB4_RS12740 94caf10c921c51e4581f8692fc4e8a74 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.4E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS12740 94caf10c921c51e4581f8692fc4e8a74 290 Gene3D G3DSA:3.40.190.10 88 175 1.1E-23 T 29-03-2018 CB4_RS12740 94caf10c921c51e4581f8692fc4e8a74 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS12740 94caf10c921c51e4581f8692fc4e8a74 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS12740 94caf10c921c51e4581f8692fc4e8a74 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS12740 94caf10c921c51e4581f8692fc4e8a74 290 SUPERFAMILY SSF46785 1 111 2.49E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12740 94caf10c921c51e4581f8692fc4e8a74 290 SUPERFAMILY SSF53850 89 289 4.54E-41 T 29-03-2018 CB4_RS12740 94caf10c921c51e4581f8692fc4e8a74 290 Gene3D G3DSA:3.40.190.10 176 263 1.1E-19 T 29-03-2018 CB4_RS12740 94caf10c921c51e4581f8692fc4e8a74 290 Pfam PF03466 LysR substrate binding domain 89 287 6.3E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CB4_RS12740 94caf10c921c51e4581f8692fc4e8a74 290 Gene3D G3DSA:1.10.10.10 1 83 8.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02955 18432ecd206224d8a13cca3f99d87dc8 73 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 14 68 3.9E-20 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CB4_RS02955 18432ecd206224d8a13cca3f99d87dc8 73 PRINTS PR00124 ATP synthase C subunit signature 6 25 2.3E-16 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02955 18432ecd206224d8a13cca3f99d87dc8 73 PRINTS PR00124 ATP synthase C subunit signature 27 42 2.3E-16 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02955 18432ecd206224d8a13cca3f99d87dc8 73 PRINTS PR00124 ATP synthase C subunit signature 44 69 2.3E-16 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02955 18432ecd206224d8a13cca3f99d87dc8 73 SUPERFAMILY SSF81333 4 69 1.57E-17 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CB4_RS02955 18432ecd206224d8a13cca3f99d87dc8 73 ProSitePatterns PS00605 ATP synthase c subunit signature. 34 55 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02955 18432ecd206224d8a13cca3f99d87dc8 73 Gene3D G3DSA:1.20.20.10 3 70 4.8E-16 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CB4_RS02955 18432ecd206224d8a13cca3f99d87dc8 73 Hamap MF_01396 ATP synthase subunit c [atpH]. 4 69 14.644 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02955 18432ecd206224d8a13cca3f99d87dc8 73 Pfam PF00137 ATP synthase subunit C 5 68 1.2E-10 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Gene3D G3DSA:3.30.420.110 128 260 7.0E-21 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 SUPERFAMILY SSF48334 265 567 1.83E-89 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 SUPERFAMILY SSF55271 2 111 2.62E-43 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Gene3D G3DSA:3.40.1170.10 1 127 9.7E-49 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 SUPERFAMILY SSF52540 569 801 1.17E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 3 894 0.0 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Pfam PF05192 MutS domain III 268 561 2.8E-43 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Gene3D G3DSA:3.40.50.300 569 802 2.2E-40 T 29-03-2018 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 SMART SM00533 282 593 7.8E-104 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Pfam PF00488 MutS domain V 614 797 1.2E-79 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 3 888 25.124 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Pfam PF05188 MutS domain II 124 250 1.2E-10 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 691 707 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Gene3D G3DSA:1.10.1420.10 409 537 5.1E-32 T 29-03-2018 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Pfam PF01624 MutS domain I 4 114 9.9E-47 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 SUPERFAMILY SSF53150 113 278 6.93E-34 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Gene3D G3DSA:1.10.1420.10 261 408 7.7E-39 T 29-03-2018 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 SMART SM00534 610 797 6.1E-113 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 PIRSF PIRSF037677 1 184 1.9E-35 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 PIRSF PIRSF037677 200 850 1.8E-139 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CB4_RS14670 1e15c7c80093d7820ded2f30c85be63a 896 Pfam PF05190 MutS family domain IV 429 520 1.0E-29 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CB4_RS18240 210d53f83fce98ae0566eb95a9d453db 192 Gene3D G3DSA:3.30.110.10 100 192 7.1E-35 T 29-03-2018 CB4_RS18240 210d53f83fce98ae0566eb95a9d453db 192 SUPERFAMILY SSF54364 26 99 1.7E-30 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CB4_RS18240 210d53f83fce98ae0566eb95a9d453db 192 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 28 96 2.1E-35 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CB4_RS18240 210d53f83fce98ae0566eb95a9d453db 192 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 104 189 2.4E-38 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CB4_RS18240 210d53f83fce98ae0566eb95a9d453db 192 Gene3D G3DSA:3.10.20.80 23 99 2.0E-35 T 29-03-2018 CB4_RS18240 210d53f83fce98ae0566eb95a9d453db 192 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 28 190 9.6E-72 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CB4_RS18240 210d53f83fce98ae0566eb95a9d453db 192 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 22 191 31.596 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CB4_RS18240 210d53f83fce98ae0566eb95a9d453db 192 SUPERFAMILY SSF55200 103 191 3.92E-33 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CB4_RS18240 210d53f83fce98ae0566eb95a9d453db 192 ProSitePatterns PS00938 Initiation factor 3 signature. 79 92 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CB4_RS14335 b6e4b5d57dcdd20568adcf33eb2aa65f 229 Pfam PF02659 Putative manganese efflux pump 130 225 1.4E-12 T 29-03-2018 IPR003810 Putative manganese efflux pump CB4_RS14335 b6e4b5d57dcdd20568adcf33eb2aa65f 229 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 4 228 2.0E-58 T 29-03-2018 IPR014205 Sporulation protein YtaF CB4_RS12080 ea5d3f2209359f8329ee6da3f771196f 261 Gene3D G3DSA:3.90.850.10 1 261 7.8E-53 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS12080 ea5d3f2209359f8329ee6da3f771196f 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 88 256 1.7E-10 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS12080 ea5d3f2209359f8329ee6da3f771196f 261 SUPERFAMILY SSF56529 4 260 3.4E-80 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 Gene3D G3DSA:3.40.50.720 49 260 8.1E-56 T 29-03-2018 CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 1.1E-56 T 29-03-2018 CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 SUPERFAMILY SSF51735 7 257 3.51E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.4E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS18060 eb58ca5e3400ddf01ab36083e245818e 261 Gene3D G3DSA:3.40.50.10090 1 48 9.1E-11 T 29-03-2018 CB4_RS14460 4ef26ae0ea64683ad2963008f73cfc7e 224 Gene3D G3DSA:3.40.50.2300 1 125 2.3E-29 T 29-03-2018 CB4_RS14460 4ef26ae0ea64683ad2963008f73cfc7e 224 SMART SM00448 2 112 2.4E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS14460 4ef26ae0ea64683ad2963008f73cfc7e 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 1.5E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS14460 4ef26ae0ea64683ad2963008f73cfc7e 224 SMART SM00862 148 223 1.0E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS14460 4ef26ae0ea64683ad2963008f73cfc7e 224 Gene3D G3DSA:1.10.10.10 126 224 2.5E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14460 4ef26ae0ea64683ad2963008f73cfc7e 224 SUPERFAMILY SSF52172 1 128 1.71E-33 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS14460 4ef26ae0ea64683ad2963008f73cfc7e 224 SUPERFAMILY SSF46894 124 223 1.76E-26 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS14460 4ef26ae0ea64683ad2963008f73cfc7e 224 Pfam PF00072 Response regulator receiver domain 4 113 4.9E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 194 318 2.7E-15 T 29-03-2018 IPR000014 PAS domain CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 Pfam PF00990 Diguanylate cyclase, GGDEF domain 330 490 7.1E-53 T 29-03-2018 IPR000160 GGDEF domain CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 Gene3D G3DSA:3.30.450.20 180 326 8.5E-22 T 29-03-2018 CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 328 492 2.9E-53 T 29-03-2018 IPR000160 GGDEF domain CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 SMART SM00267 318 493 8.7E-65 T 29-03-2018 IPR000160 GGDEF domain CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 SMART SM00091 198 264 2.0E-7 T 29-03-2018 IPR000014 PAS domain CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 SUPERFAMILY SSF55785 188 309 1.55E-13 T 29-03-2018 IPR000014 PAS domain CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 Pfam PF00989 PAS fold 198 308 8.7E-6 T 29-03-2018 IPR013767 PAS fold GO:0006355 CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 Pfam PF07694 5TMR of 5TMR-LYT 22 152 1.8E-13 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 SUPERFAMILY SSF55073 334 492 6.98E-52 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS12570 f9440e6e6867730f536a1959d58261cd 493 Gene3D G3DSA:3.30.70.270 327 493 1.6E-54 T 29-03-2018 CB4_RS17945 921c2435477235dbc725a4af16a939a4 422 Pfam PF00534 Glycosyl transferases group 1 213 379 5.4E-35 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CB4_RS17945 921c2435477235dbc725a4af16a939a4 422 SUPERFAMILY SSF53756 4 402 8.64E-81 T 29-03-2018 CB4_RS17945 921c2435477235dbc725a4af16a939a4 422 Pfam PF13439 Glycosyltransferase Family 4 23 192 2.5E-26 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CB4_RS17945 921c2435477235dbc725a4af16a939a4 422 Gene3D G3DSA:3.40.50.2000 203 385 5.3E-44 T 29-03-2018 CB4_RS17945 921c2435477235dbc725a4af16a939a4 422 Gene3D G3DSA:3.40.50.2000 17 202 7.5E-14 T 29-03-2018 CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 Pfam PF00072 Response regulator receiver domain 5 113 3.1E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 153 180 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 SMART SM00448 2 113 5.4E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 138 192 1.6E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 Gene3D G3DSA:3.40.50.2300 1 145 6.8E-25 T 29-03-2018 CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 181 1.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 153 1.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 169 1.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 Gene3D G3DSA:1.10.10.10 146 199 3.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 SUPERFAMILY SSF52172 1 124 9.39E-27 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 SMART SM00421 136 193 3.7E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS19945 448b41f6979e47a8a3d849ea2515eb6b 200 SUPERFAMILY SSF46894 128 198 2.89E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS03585 2c8b5a50511cf9ce90a2389acc568fcd 417 SUPERFAMILY SSF69864 171 398 1.57E-90 T 29-03-2018 CB4_RS03585 2c8b5a50511cf9ce90a2389acc568fcd 417 Gene3D G3DSA:3.40.50.620 4 158 7.0E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS03585 2c8b5a50511cf9ce90a2389acc568fcd 417 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 394 2.0E-166 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03585 2c8b5a50511cf9ce90a2389acc568fcd 417 Gene3D G3DSA:1.20.5.470 363 395 4.3E-7 T 29-03-2018 CB4_RS03585 2c8b5a50511cf9ce90a2389acc568fcd 417 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03585 2c8b5a50511cf9ce90a2389acc568fcd 417 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03585 2c8b5a50511cf9ce90a2389acc568fcd 417 SUPERFAMILY SSF52402 3 165 7.06E-47 T 29-03-2018 CB4_RS03585 2c8b5a50511cf9ce90a2389acc568fcd 417 Gene3D G3DSA:3.90.1260.10 159 353 2.0E-83 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03585 2c8b5a50511cf9ce90a2389acc568fcd 417 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 397 54.299 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03585 2c8b5a50511cf9ce90a2389acc568fcd 417 Pfam PF00764 Arginosuccinate synthase 7 392 2.1E-176 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS16215 51c7b6362b07e587d243d6cd3f9354a5 397 SMART SM00936 288 379 2.6E-19 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CB4_RS16215 51c7b6362b07e587d243d6cd3f9354a5 397 Gene3D G3DSA:2.60.410.10 305 379 4.8E-19 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CB4_RS16215 51c7b6362b07e587d243d6cd3f9354a5 397 SUPERFAMILY SSF56601 3 288 3.66E-79 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS16215 51c7b6362b07e587d243d6cd3f9354a5 397 SUPERFAMILY SSF69189 280 378 3.92E-18 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CB4_RS16215 51c7b6362b07e587d243d6cd3f9354a5 397 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 288 379 2.6E-18 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CB4_RS16215 51c7b6362b07e587d243d6cd3f9354a5 397 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 41 267 1.3E-79 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CB4_RS16215 51c7b6362b07e587d243d6cd3f9354a5 397 Gene3D G3DSA:3.40.710.10 19 304 4.0E-62 T 29-03-2018 CB4_RS16215 51c7b6362b07e587d243d6cd3f9354a5 397 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 8.0E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS16215 51c7b6362b07e587d243d6cd3f9354a5 397 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 71 82 8.0E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS16215 51c7b6362b07e587d243d6cd3f9354a5 397 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 8.0E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS03865 a39aa2bf233a55908a80e848568452a4 254 SUPERFAMILY SSF51351 2 248 1.44E-93 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03865 a39aa2bf233a55908a80e848568452a4 254 Gene3D G3DSA:3.20.20.70 1 252 9.4E-104 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS03865 a39aa2bf233a55908a80e848568452a4 254 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03865 a39aa2bf233a55908a80e848568452a4 254 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 241 5.6E-60 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03865 a39aa2bf233a55908a80e848568452a4 254 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 250 40.752 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03865 a39aa2bf233a55908a80e848568452a4 254 Pfam PF00121 Triosephosphate isomerase 6 247 3.4E-94 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18390 884e276c571fdd6bf5729119a2cf36f2 424 SMART SM01329 23 420 4.3E-184 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CB4_RS18390 884e276c571fdd6bf5729119a2cf36f2 424 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 24 419 3.4E-119 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CB4_RS18390 884e276c571fdd6bf5729119a2cf36f2 424 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 424 1.2E-224 T 29-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CB4_RS18390 884e276c571fdd6bf5729119a2cf36f2 424 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 309 328 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CB4_RS18390 884e276c571fdd6bf5729119a2cf36f2 424 SUPERFAMILY SSF53659 7 424 5.95E-141 T 29-03-2018 CB4_RS18390 884e276c571fdd6bf5729119a2cf36f2 424 Gene3D G3DSA:3.40.718.10 12 424 5.4E-137 T 29-03-2018 CB4_RS14500 c23958cbd7ad577c3733877ab2a08d67 379 SUPERFAMILY SSF53098 84 329 1.37E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS14500 c23958cbd7ad577c3733877ab2a08d67 379 Pfam PF01609 Transposase DDE domain 111 320 1.0E-31 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CB4_RS14500 c23958cbd7ad577c3733877ab2a08d67 379 Gene3D G3DSA:3.90.350.10 89 296 4.5E-22 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CB4_RS12825 78d0dfa59c4a6b316da6c730559bd3aa 186 Gene3D G3DSA:1.10.260.40 1 77 1.3E-18 T 29-03-2018 CB4_RS12825 78d0dfa59c4a6b316da6c730559bd3aa 186 SMART SM00530 9 64 5.4E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS12825 78d0dfa59c4a6b316da6c730559bd3aa 186 Pfam PF07883 Cupin domain 110 180 3.6E-13 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CB4_RS12825 78d0dfa59c4a6b316da6c730559bd3aa 186 SUPERFAMILY SSF51182 50 184 1.76E-23 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS12825 78d0dfa59c4a6b316da6c730559bd3aa 186 Gene3D G3DSA:2.60.120.10 78 184 4.3E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS12825 78d0dfa59c4a6b316da6c730559bd3aa 186 SUPERFAMILY SSF47413 2 68 4.02E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS12825 78d0dfa59c4a6b316da6c730559bd3aa 186 Pfam PF01381 Helix-turn-helix 13 61 3.8E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS17775 344e589b3a6ee0b5e8ca2f9d54048c1e 232 SUPERFAMILY SSF52402 5 230 1.17E-69 T 29-03-2018 CB4_RS17775 344e589b3a6ee0b5e8ca2f9d54048c1e 232 Gene3D G3DSA:3.40.50.620 4 232 1.7E-54 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS17775 344e589b3a6ee0b5e8ca2f9d54048c1e 232 PIRSF PIRSF006293 3 231 6.1E-82 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CB4_RS17775 344e589b3a6ee0b5e8ca2f9d54048c1e 232 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 5 226 56.197 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CB4_RS17775 344e589b3a6ee0b5e8ca2f9d54048c1e 232 Pfam PF06508 Queuosine biosynthesis protein QueC 6 220 1.0E-81 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CB4_RS17775 344e589b3a6ee0b5e8ca2f9d54048c1e 232 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 7 213 3.3E-70 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CB4_RS15370 e2a8848aa042824b9dfe49f8f163fd2e 181 PRINTS PR00138 Matrixin signature 129 154 9.9E-6 T 29-03-2018 IPR021190 Peptidase M10A GO:0004222|GO:0006508|GO:0008270|GO:0031012 CB4_RS15370 e2a8848aa042824b9dfe49f8f163fd2e 181 PRINTS PR00138 Matrixin signature 168 181 9.9E-6 T 29-03-2018 IPR021190 Peptidase M10A GO:0004222|GO:0006508|GO:0008270|GO:0031012 CB4_RS15370 e2a8848aa042824b9dfe49f8f163fd2e 181 SUPERFAMILY SSF55486 27 181 3.15E-23 T 29-03-2018 CB4_RS15370 e2a8848aa042824b9dfe49f8f163fd2e 181 Gene3D G3DSA:3.40.390.10 17 181 2.4E-22 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CB4_RS15370 e2a8848aa042824b9dfe49f8f163fd2e 181 SMART SM00235 27 181 1.5E-4 T 29-03-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 CB4_RS15370 e2a8848aa042824b9dfe49f8f163fd2e 181 Pfam PF00413 Matrixin 58 180 5.7E-11 T 29-03-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 CB4_RS09115 b5c12c8474bedd93e871b04362d8e862 301 Pfam PF03448 MgtE intracellular N domain 144 199 1.1E-7 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CB4_RS09115 b5c12c8474bedd93e871b04362d8e862 301 SUPERFAMILY SSF158791 127 199 4.05E-9 T 29-03-2018 CB4_RS09115 b5c12c8474bedd93e871b04362d8e862 301 Gene3D G3DSA:1.10.220.30 150 228 8.3E-11 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CB4_RS09115 b5c12c8474bedd93e871b04362d8e862 301 Gene3D G3DSA:1.10.220.30 229 297 1.4E-5 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CB4_RS09115 b5c12c8474bedd93e871b04362d8e862 301 Gene3D G3DSA:1.20.1000.10 32 149 4.2E-5 T 29-03-2018 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 1 176 19.155 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 4 173 2.9E-54 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 4 173 3.3E-48 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 PRINTS PR00125 ATP synthase delta subunit signature 4 23 4.2E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 PRINTS PR00125 ATP synthase delta subunit signature 134 149 4.2E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 PRINTS PR00125 ATP synthase delta subunit signature 73 84 4.2E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 PRINTS PR00125 ATP synthase delta subunit signature 84 98 4.2E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 PRINTS PR00125 ATP synthase delta subunit signature 149 167 4.2E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 136 155 - T 29-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 SUPERFAMILY SSF47928 2 104 1.44E-22 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02965 d00dec78bed4c7dcf5a0ef0604fdd24e 179 Gene3D G3DSA:1.10.520.20 1 105 9.1E-28 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 Gene3D G3DSA:1.20.5.140 166 182 2.8E-6 T 29-03-2018 CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 Pfam PF00929 Exonuclease 17 172 4.1E-34 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 14 956 1.9E-251 T 29-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 SUPERFAMILY SSF52540 696 710 2.49E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 SUPERFAMILY SSF52540 747 919 2.49E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 SUPERFAMILY SSF52540 432 502 2.49E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 SUPERFAMILY SSF52540 286 343 2.49E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 Gene3D G3DSA:3.30.420.10 6 165 3.9E-39 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 SMART SM00488 266 529 0.001 T 29-03-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 Pfam PF04851 Type III restriction enzyme, res subunit 273 487 7.0E-9 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 SMART SM00479 14 181 1.5E-47 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 Pfam PF13307 Helicase C-terminal domain 775 938 9.8E-39 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 SMART SM00491 791 925 1.9E-32 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 Gene3D G3DSA:3.40.50.300 272 720 8.4E-35 T 29-03-2018 CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 11 181 1.4E-28 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 SMART SM00487 271 536 3.3E-11 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 Gene3D G3DSA:3.40.50.300 754 938 1.3E-13 T 29-03-2018 CB4_RS14950 0afe39c02c00a7b6af40e612ae07b718 960 SUPERFAMILY SSF53098 11 192 1.64E-53 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS08080 09fb6522f52a8a6097c1207702ef3b16 489 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 368 4.4E-105 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CB4_RS08080 09fb6522f52a8a6097c1207702ef3b16 489 Gene3D G3DSA:3.40.640.10 6 284 1.2E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS08080 09fb6522f52a8a6097c1207702ef3b16 489 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 401 458 1.5E-11 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CB4_RS08080 09fb6522f52a8a6097c1207702ef3b16 489 Gene3D G3DSA:3.90.100.10 402 487 1.7E-27 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CB4_RS08080 09fb6522f52a8a6097c1207702ef3b16 489 SUPERFAMILY SSF53383 6 384 2.15E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS08080 09fb6522f52a8a6097c1207702ef3b16 489 SUPERFAMILY SSF55904 342 485 4.05E-39 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CB4_RS08080 09fb6522f52a8a6097c1207702ef3b16 489 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 221 235 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CB4_RS08080 09fb6522f52a8a6097c1207702ef3b16 489 Gene3D G3DSA:3.90.1150.10 309 401 2.1E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS01110 9373d9a031b66a5036edd6a3009d5e34 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.352 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CB4_RS01110 9373d9a031b66a5036edd6a3009d5e34 156 Gene3D G3DSA:1.10.455.10 6 156 2.0E-59 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CB4_RS01110 9373d9a031b66a5036edd6a3009d5e34 156 SUPERFAMILY SSF47973 1 149 3.27E-61 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CB4_RS01110 9373d9a031b66a5036edd6a3009d5e34 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS01110 9373d9a031b66a5036edd6a3009d5e34 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.7E-65 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CB4_RS01110 9373d9a031b66a5036edd6a3009d5e34 156 PIRSF PIRSF002122 5 156 8.4E-58 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CB4_RS01110 9373d9a031b66a5036edd6a3009d5e34 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 8.1E-70 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CB4_RS14995 9c4335caca763d3557313ee06a7b6dfe 139 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 2 122 1.7E-57 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CB4_RS14995 9c4335caca763d3557313ee06a7b6dfe 139 Pfam PF02142 MGS-like domain 14 107 8.1E-19 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS14995 9c4335caca763d3557313ee06a7b6dfe 139 PIRSF PIRSF006614 1 137 6.5E-60 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CB4_RS14995 9c4335caca763d3557313ee06a7b6dfe 139 Gene3D G3DSA:3.40.50.1380 1 133 2.9E-38 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS14995 9c4335caca763d3557313ee06a7b6dfe 139 SMART SM00851 14 107 1.2E-26 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS14995 9c4335caca763d3557313ee06a7b6dfe 139 SUPERFAMILY SSF52335 1 131 8.37E-55 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS14995 9c4335caca763d3557313ee06a7b6dfe 139 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 62 - T 29-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CB4_RS14995 9c4335caca763d3557313ee06a7b6dfe 139 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 36.209 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CB4_RS17240 11049492786ba84c524180ef7802d56b 398 PIRSF PIRSF001413 1 398 3.4E-168 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS17240 11049492786ba84c524180ef7802d56b 398 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 393 51.887 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS17240 11049492786ba84c524180ef7802d56b 398 Gene3D G3DSA:3.40.50.1100 11 70 9.0E-8 T 29-03-2018 CB4_RS17240 11049492786ba84c524180ef7802d56b 398 Gene3D G3DSA:3.40.50.1100 71 200 2.7E-37 T 29-03-2018 CB4_RS17240 11049492786ba84c524180ef7802d56b 398 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 9 392 1.3E-188 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS17240 11049492786ba84c524180ef7802d56b 398 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS17240 11049492786ba84c524180ef7802d56b 398 Gene3D G3DSA:3.40.50.1100 201 397 1.7E-37 T 29-03-2018 CB4_RS17240 11049492786ba84c524180ef7802d56b 398 SUPERFAMILY SSF53686 7 391 9.82E-146 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS17240 11049492786ba84c524180ef7802d56b 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 54 380 9.5E-50 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS12645 13441b39c6d87256ec51f9c54612a24a 364 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 358 7.9E-67 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS12645 13441b39c6d87256ec51f9c54612a24a 364 Pfam PF03845 Spore germination protein 6 315 5.5E-59 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS10665 2c6d0b805fea074e433911a86e62007f 193 SUPERFAMILY SSF46689 6 67 2.93E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS10665 2c6d0b805fea074e433911a86e62007f 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.6E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS10665 2c6d0b805fea074e433911a86e62007f 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.6E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS10665 2c6d0b805fea074e433911a86e62007f 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 53 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CB4_RS10665 2c6d0b805fea074e433911a86e62007f 193 Gene3D G3DSA:1.10.10.60 5 45 1.1E-18 T 29-03-2018 CB4_RS10665 2c6d0b805fea074e433911a86e62007f 193 Gene3D G3DSA:1.10.10.60 46 177 4.8E-9 T 29-03-2018 CB4_RS10665 2c6d0b805fea074e433911a86e62007f 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.8E-19 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 Gene3D G3DSA:3.90.226.10 5 312 4.4E-69 T 29-03-2018 CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 50.414 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 6.9E-66 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 7.4E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 7.4E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 7.4E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 7.4E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 7.4E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 7.4E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 SUPERFAMILY SSF52096 7 315 3.13E-104 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS18420 beef0f800d70385bf6eee3a53d3f0145 321 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 4 318 4.1E-153 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS20395 2c51f76f9aab7df2b13175cf7b1b6135 379 Gene3D G3DSA:3.30.1490.20 110 195 2.7E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS20395 2c51f76f9aab7df2b13175cf7b1b6135 379 SUPERFAMILY SSF56059 109 309 6.19E-65 T 29-03-2018 CB4_RS20395 2c51f76f9aab7df2b13175cf7b1b6135 379 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 13 365 43.804 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CB4_RS20395 2c51f76f9aab7df2b13175cf7b1b6135 379 SUPERFAMILY SSF51246 313 378 1.1E-14 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CB4_RS20395 2c51f76f9aab7df2b13175cf7b1b6135 379 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 13 367 1.1E-128 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CB4_RS20395 2c51f76f9aab7df2b13175cf7b1b6135 379 SUPERFAMILY SSF52440 9 101 3.31E-25 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS20395 2c51f76f9aab7df2b13175cf7b1b6135 379 Gene3D G3DSA:3.30.470.20 196 376 1.3E-45 T 29-03-2018 CB4_RS20395 2c51f76f9aab7df2b13175cf7b1b6135 379 Pfam PF02222 ATP-grasp domain 118 289 6.4E-61 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CB4_RS20395 2c51f76f9aab7df2b13175cf7b1b6135 379 Gene3D G3DSA:3.40.50.20 12 97 9.7E-21 T 29-03-2018 CB4_RS09750 5344025886622571921741294c09082b 394 Pfam PF00155 Aminotransferase class I and II 36 383 7.0E-72 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS09750 5344025886622571921741294c09082b 394 Gene3D G3DSA:3.90.1150.10 300 392 4.2E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS09750 5344025886622571921741294c09082b 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CB4_RS09750 5344025886622571921741294c09082b 394 SUPERFAMILY SSF53383 10 388 4.39E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS09750 5344025886622571921741294c09082b 394 Gene3D G3DSA:3.40.640.10 49 299 2.4E-66 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS07795 7b7db5b552b012011c9228b146d6c2cc 130 Gene3D G3DSA:1.10.1660.10 1 60 4.7E-21 T 29-03-2018 CB4_RS07795 7b7db5b552b012011c9228b146d6c2cc 130 SUPERFAMILY SSF46955 5 119 5.86E-29 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS07795 7b7db5b552b012011c9228b146d6c2cc 130 SMART SM00422 5 74 4.1E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS07795 7b7db5b552b012011c9228b146d6c2cc 130 Pfam PF13411 MerR HTH family regulatory protein 6 72 1.1E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS07795 7b7db5b552b012011c9228b146d6c2cc 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 2.1E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS07795 7b7db5b552b012011c9228b146d6c2cc 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 2.1E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS07795 7b7db5b552b012011c9228b146d6c2cc 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 2.1E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS07795 7b7db5b552b012011c9228b146d6c2cc 130 Gene3D G3DSA:1.10.1660.10 61 129 3.0E-14 T 29-03-2018 CB4_RS15960 305c9705df77a5bbf0294975c5dc622f 537 Pfam PF05140 ResB-like family 63 514 5.3E-87 T 29-03-2018 IPR007816 ResB-like domain CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 PIRSF PIRSF036480 1 278 3.4E-116 T 29-03-2018 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 2 277 1.3E-125 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 1 27 2.6E-62 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 34 46 2.6E-62 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 106 133 2.6E-62 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 229 251 2.6E-62 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 276 2.6E-62 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 84 106 2.6E-62 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 SUPERFAMILY SSF53328 83 278 3.27E-60 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 Gene3D G3DSA:3.30.70.260 1 84 3.1E-24 T 29-03-2018 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 277 45.337 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 Pfam PF01842 ACT domain 3 61 5.9E-8 T 29-03-2018 IPR002912 ACT domain CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 Pfam PF00551 Formyl transferase 83 259 1.1E-39 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 SUPERFAMILY SSF55021 2 80 6.66E-17 T 29-03-2018 CB4_RS17000 2d69f2c0eb0442c33eab15866a0b9bc6 278 Gene3D G3DSA:3.40.50.170 85 277 2.0E-55 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 PRINTS PR00397 Sirohaem Fe-binding site signature 436 454 4.5E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 PRINTS PR00397 Sirohaem Fe-binding site signature 392 410 4.5E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 62 128 2.5E-20 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 314 377 3.5E-17 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 SUPERFAMILY SSF56014 395 535 9.55E-34 T 29-03-2018 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 Gene3D G3DSA:3.30.413.10 391 534 7.5E-29 T 29-03-2018 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 Gene3D G3DSA:3.90.480.10 66 210 6.8E-20 T 29-03-2018 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 Gene3D G3DSA:3.90.480.10 234 384 2.3E-29 T 29-03-2018 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 SUPERFAMILY SSF55124 272 403 5.56E-22 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 SUPERFAMILY SSF55124 11 136 4.58E-33 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 SUPERFAMILY SSF56014 137 294 1.31E-44 T 29-03-2018 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 395 536 7.1E-13 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CB4_RS19365 5479d77d5611d9725ef0cb5b6a1b90d8 539 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 137 292 4.0E-38 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CB4_RS03810 00985398fdb8bd8af0d283095cf1da40 315 Gene3D G3DSA:3.10.28.10 13 100 5.5E-11 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CB4_RS03810 00985398fdb8bd8af0d283095cf1da40 315 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 33.848 T 29-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CB4_RS03810 00985398fdb8bd8af0d283095cf1da40 315 Gene3D G3DSA:3.10.28.10 122 202 8.8E-17 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CB4_RS03810 00985398fdb8bd8af0d283095cf1da40 315 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 103 4.7E-37 T 29-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CB4_RS03810 00985398fdb8bd8af0d283095cf1da40 315 Pfam PF14527 WhiA LAGLIDADG-like domain 124 216 1.5E-33 T 29-03-2018 CB4_RS03810 00985398fdb8bd8af0d283095cf1da40 315 SUPERFAMILY SSF55608 121 218 9.64E-16 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CB4_RS03810 00985398fdb8bd8af0d283095cf1da40 315 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 303 1.2E-118 T 29-03-2018 IPR033981 Sporulation regulator WhiA-like CB4_RS03810 00985398fdb8bd8af0d283095cf1da40 315 Pfam PF02650 WhiA C-terminal HTH domain 219 303 4.1E-33 T 29-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 Pfam PF00108 Thiolase, N-terminal domain 9 268 1.1E-85 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 Gene3D G3DSA:3.40.47.10 1 277 2.1E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 ProSitePatterns PS00737 Thiolases signature 2. 345 361 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 397 3.5E-146 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 Pfam PF02803 Thiolase, C-terminal domain 277 397 2.0E-49 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 SUPERFAMILY SSF53901 277 397 1.32E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 PIRSF PIRSF000429 2 399 2.4E-136 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 Gene3D G3DSA:3.40.47.10 278 396 3.1E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS05095 e2e51feb089dd92f1800627c1476bb94 399 SUPERFAMILY SSF53901 7 275 1.44E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09355 f63b935016f1cfebb9309b6fdb02d666 89 Pfam PF00312 Ribosomal protein S15 8 88 3.0E-38 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS09355 f63b935016f1cfebb9309b6fdb02d666 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS09355 f63b935016f1cfebb9309b6fdb02d666 89 SMART SM01387 8 88 1.3E-53 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS09355 f63b935016f1cfebb9309b6fdb02d666 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 5.0E-32 T 29-03-2018 CB4_RS09355 f63b935016f1cfebb9309b6fdb02d666 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 6.6E-42 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS09355 f63b935016f1cfebb9309b6fdb02d666 89 Gene3D G3DSA:1.10.287.10 2 89 5.2E-37 T 29-03-2018 CB4_RS09355 f63b935016f1cfebb9309b6fdb02d666 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.878 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS09355 f63b935016f1cfebb9309b6fdb02d666 89 SUPERFAMILY SSF47060 3 89 4.12E-37 T 29-03-2018 IPR009068 S15/NS1, RNA-binding CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 SUPERFAMILY SSF48179 182 333 1.5E-56 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 SUPERFAMILY SSF51735 5 180 6.06E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 6 162 2.9E-51 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 324 38.285 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 Gene3D G3DSA:1.10.1040.10 191 339 1.4E-54 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 190 211 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 PIRSF PIRSF000114 1 334 1.1E-103 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 182 322 5.6E-53 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 135 155 5.3E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 5.3E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 240 257 5.3E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 5.3E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 175 199 5.3E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 200 224 5.3E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CB4_RS15225 1a51793056a973b91f1bfc88a16a5e9c 345 Gene3D G3DSA:3.40.50.720 1 180 4.5E-42 T 29-03-2018 CB4_RS13585 3fa1144fdac0412b29c3d88f7fbfde57 331 Gene3D G3DSA:3.40.1090.10 1 285 2.5E-5 T 29-03-2018 CB4_RS11805 f6aa2ddfe3423b8fe302b1915a8a2490 194 Pfam PF04542 Sigma-70 region 2 41 101 1.4E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11805 f6aa2ddfe3423b8fe302b1915a8a2490 194 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 179 3.8E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS11805 f6aa2ddfe3423b8fe302b1915a8a2490 194 Gene3D G3DSA:1.10.1740.10 14 108 1.8E-10 T 29-03-2018 CB4_RS11805 f6aa2ddfe3423b8fe302b1915a8a2490 194 SUPERFAMILY SSF46894 128 181 4.08E-6 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS11805 f6aa2ddfe3423b8fe302b1915a8a2490 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 174 3.0E-15 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11805 f6aa2ddfe3423b8fe302b1915a8a2490 194 SUPERFAMILY SSF88946 18 119 9.1E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11805 f6aa2ddfe3423b8fe302b1915a8a2490 194 Gene3D G3DSA:1.10.10.10 109 182 4.2E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS01630 2a929aa702b82c3513cd11e8053c2dab 88 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 8 87 3.7E-22 T 29-03-2018 IPR010001 SigmaK-factor processing regulatory BofA CB4_RS01630 2a929aa702b82c3513cd11e8053c2dab 88 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 86 1.9E-20 T 29-03-2018 IPR010001 SigmaK-factor processing regulatory BofA CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 Pfam PF02464 Competence-damaged protein 257 407 2.3E-47 T 29-03-2018 IPR008136 CinA, C-terminal CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 SUPERFAMILY SSF53218 1 206 2.49E-40 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 163 3.8E-31 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 SMART SM00852 4 171 1.2E-38 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 Gene3D G3DSA:3.40.980.10 1 171 1.2E-43 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 410 8.2E-144 T 29-03-2018 IPR008135 Competence-induced protein CinA CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 PIRSF PIRSF006728 1 413 2.2E-152 T 29-03-2018 IPR008135 Competence-induced protein CinA CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 264 403 8.4E-36 T 29-03-2018 IPR008136 CinA, C-terminal CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 SUPERFAMILY SSF142433 250 408 1.57E-43 T 29-03-2018 IPR008136 CinA, C-terminal CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 Gene3D G3DSA:3.90.950.20 247 413 1.5E-52 T 29-03-2018 CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 Pfam PF00994 Probable molybdopterin binding domain 4 167 1.6E-32 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS14810 b2f8bd7509e5058413f19c9523143330 414 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 414 164.599 T 29-03-2018 IPR008135 Competence-induced protein CinA CB4_RS06185 0d97f7acff81c1b6d189b7eda3707b09 172 SUPERFAMILY SSF88874 1 166 4.45E-49 T 29-03-2018 CB4_RS06185 0d97f7acff81c1b6d189b7eda3707b09 172 Gene3D G3DSA:3.90.1340.10 1 54 2.6E-20 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS06185 0d97f7acff81c1b6d189b7eda3707b09 172 Gene3D G3DSA:4.10.1070.10 55 155 3.1E-7 T 29-03-2018 CB4_RS06185 0d97f7acff81c1b6d189b7eda3707b09 172 Pfam PF07484 Phage Tail Collar Domain 7 63 4.0E-26 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS05575 79759f47d642bf93527f17adbe6ae608 270 Gene3D G3DSA:3.40.50.1860 1 111 5.3E-25 T 29-03-2018 CB4_RS05575 79759f47d642bf93527f17adbe6ae608 270 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 214 3.1E-38 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS05575 79759f47d642bf93527f17adbe6ae608 270 SUPERFAMILY SSF53681 108 260 1.18E-38 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS05575 79759f47d642bf93527f17adbe6ae608 270 Gene3D G3DSA:3.40.50.1860 112 267 1.2E-43 T 29-03-2018 CB4_RS05575 79759f47d642bf93527f17adbe6ae608 270 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS05575 79759f47d642bf93527f17adbe6ae608 270 Hamap MF_00258 Glutamate racemase [murI]. 3 257 39.053 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS05575 79759f47d642bf93527f17adbe6ae608 270 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 254 2.7E-80 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS05575 79759f47d642bf93527f17adbe6ae608 270 SUPERFAMILY SSF53681 4 105 7.52E-34 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 SUPERFAMILY SSF52518 311 498 1.3E-62 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 1 620 46.309 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 ProSitePatterns PS00802 Transketolase signature 2. 419 435 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 SMART SM00861 313 477 2.3E-72 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 ProSitePatterns PS00801 Transketolase signature 1. 27 46 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 2 277 6.9E-123 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 Pfam PF02780 Transketolase, C-terminal domain 489 611 8.1E-32 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 3 615 2.7E-277 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 Gene3D G3DSA:3.40.50.920 489 619 5.8E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 SUPERFAMILY SSF52518 3 190 2.6E-80 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 SUPERFAMILY SSF52518 238 375 2.6E-80 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 Gene3D G3DSA:3.40.50.970 1 302 2.7E-84 T 29-03-2018 CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 SUPERFAMILY SSF52922 486 617 1.96E-36 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 Pfam PF02779 Transketolase, pyrimidine binding domain 313 473 1.5E-41 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CB4_RS07985 11dc7be9252ee5f33c42753170e679d7 626 Gene3D G3DSA:3.40.50.970 303 478 4.5E-47 T 29-03-2018 CB4_RS14765 8617a44a5c981c62091613dc05ae87be 578 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 175 8.7E-42 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CB4_RS14765 8617a44a5c981c62091613dc05ae87be 578 Gene3D G3DSA:3.40.920.10 2 181 5.3E-43 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CB4_RS14765 8617a44a5c981c62091613dc05ae87be 578 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 475 566 4.1E-15 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CB4_RS14765 8617a44a5c981c62091613dc05ae87be 578 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 573 1.3E-208 T 29-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CB4_RS14765 8617a44a5c981c62091613dc05ae87be 578 Gene3D G3DSA:3.40.50.970 195 544 3.5E-60 T 29-03-2018 CB4_RS14765 8617a44a5c981c62091613dc05ae87be 578 SUPERFAMILY SSF52518 197 458 6.73E-71 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS14765 8617a44a5c981c62091613dc05ae87be 578 SUPERFAMILY SSF52922 467 577 1.57E-23 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS14765 8617a44a5c981c62091613dc05ae87be 578 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 210 450 1.0E-59 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CB4_RS14765 8617a44a5c981c62091613dc05ae87be 578 SUPERFAMILY SSF53323 1 220 9.42E-45 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 Gene3D G3DSA:1.10.490.10 2 179 3.5E-27 T 29-03-2018 CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 Pfam PF13682 Chemoreceptor zinc-binding domain 471 537 7.3E-14 T 29-03-2018 IPR025991 Chemoreceptor zinc-binding domain CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 SUPERFAMILY SSF46458 26 171 9.82E-27 T 29-03-2018 IPR009050 Globin-like CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 Pfam PF11563 Protoglobin 24 176 4.8E-28 T 29-03-2018 CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 321 350 7.0E-15 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 215 244 7.0E-15 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 292 319 7.0E-15 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 SMART SM00283 191 457 8.4E-35 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 272 415 4.3E-34 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 Gene3D G3DSA:1.10.287.950 209 420 2.6E-46 T 29-03-2018 CB4_RS19680 04e8fd23fab385a10b78ff84a24177a1 584 SUPERFAMILY SSF58104 200 447 6.54E-55 T 29-03-2018 CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 PIRSF PIRSF000676 3 303 1.8E-93 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 Gene3D G3DSA:3.30.70.890 166 308 4.4E-31 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 SUPERFAMILY SSF55060 165 276 2.08E-32 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 Gene3D G3DSA:3.30.230.10 4 165 1.8E-35 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 Hamap MF_00384 Homoserine kinase [thrB]. 6 301 33.091 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 Pfam PF08544 GHMP kinases C terminal 204 275 3.9E-11 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 SUPERFAMILY SSF54211 5 151 2.43E-33 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 PRINTS PR00958 Homoserine kinase signature 247 262 1.9E-39 T 29-03-2018 CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 PRINTS PR00958 Homoserine kinase signature 168 185 1.9E-39 T 29-03-2018 CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 PRINTS PR00958 Homoserine kinase signature 95 110 1.9E-39 T 29-03-2018 CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 PRINTS PR00958 Homoserine kinase signature 13 28 1.9E-39 T 29-03-2018 CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 PRINTS PR00958 Homoserine kinase signature 129 142 1.9E-39 T 29-03-2018 CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 Pfam PF00288 GHMP kinases N terminal domain 82 142 6.9E-11 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 TIGRFAM TIGR00191 thrB: homoserine kinase 6 302 3.9E-88 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CB4_RS05905 ba857bfda0bf1b444dda5055ffc20bf9 310 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 88 99 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CB4_RS17320 e9670a54feabce04c85dd2ecb649522f 230 Gene3D G3DSA:3.40.50.1580 1 230 9.1E-55 T 29-03-2018 CB4_RS17320 e9670a54feabce04c85dd2ecb649522f 230 SUPERFAMILY SSF53167 1 229 4.32E-67 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CB4_RS17320 e9670a54feabce04c85dd2ecb649522f 230 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 229 9.4E-57 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CB4_RS17320 e9670a54feabce04c85dd2ecb649522f 230 Pfam PF01048 Phosphorylase superfamily 2 227 1.7E-55 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 7.6E-60 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 7.6E-60 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 7.6E-60 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 7.6E-60 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 7.6E-60 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 7.6E-60 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 PIRSF PIRSF001415 1 325 2.2E-157 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 SUPERFAMILY SSF51569 4 324 9.82E-146 T 29-03-2018 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 SMART SM01004 4 322 1.4E-239 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 321 1.0E-153 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CB4_RS05680 2d222bce5cd1ea32cdfeefc929606250 326 Gene3D G3DSA:3.20.20.70 1 326 3.8E-158 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS04040 d4e039cb3ce97fc84d7da13bdc1a20a1 459 Gene3D G3DSA:3.40.630.10 6 200 8.0E-43 T 29-03-2018 CB4_RS04040 d4e039cb3ce97fc84d7da13bdc1a20a1 459 Pfam PF01546 Peptidase family M20/M25/M40 83 451 5.8E-42 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CB4_RS04040 d4e039cb3ce97fc84d7da13bdc1a20a1 459 Gene3D G3DSA:3.30.70.360 201 365 1.3E-58 T 29-03-2018 CB4_RS04040 d4e039cb3ce97fc84d7da13bdc1a20a1 459 SUPERFAMILY SSF53187 2 197 3.83E-66 T 29-03-2018 CB4_RS04040 d4e039cb3ce97fc84d7da13bdc1a20a1 459 SUPERFAMILY SSF53187 368 454 3.83E-66 T 29-03-2018 CB4_RS04040 d4e039cb3ce97fc84d7da13bdc1a20a1 459 Pfam PF07687 Peptidase dimerisation domain 194 354 3.6E-23 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 Pfam PF00361 Proton-conducting membrane transporter 133 425 1.8E-93 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 65 120 1.3E-16 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 418 437 4.5E-62 T 29-03-2018 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 4.5E-62 T 29-03-2018 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 4.5E-62 T 29-03-2018 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 4.5E-62 T 29-03-2018 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 110 130 4.5E-62 T 29-03-2018 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 157 178 4.5E-62 T 29-03-2018 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 82 107 4.5E-62 T 29-03-2018 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 264 286 9.2E-18 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 359 381 9.2E-18 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 417 439 9.2E-18 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 84 104 9.2E-18 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 Pfam PF01010 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus 442 526 5.0E-7 T 29-03-2018 IPR002128 NADH:ubiquinone/plastoquinone oxidoreductase, chloroplast chain 5, C-terminal CB4_RS03035 6efd80ca93e47598fd70bab7544acc6f 635 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 616 1.3E-206 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS00490 9ef74f6062294722c3e7cbfddaf2d7b3 333 PRINTS PR00116 Arginase signature 248 277 8.5E-7 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00490 9ef74f6062294722c3e7cbfddaf2d7b3 333 PRINTS PR00116 Arginase signature 132 147 8.5E-7 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00490 9ef74f6062294722c3e7cbfddaf2d7b3 333 SUPERFAMILY SSF52768 33 327 4.14E-66 T 29-03-2018 CB4_RS00490 9ef74f6062294722c3e7cbfddaf2d7b3 333 PIRSF PIRSF036979 24 328 3.4E-48 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00490 9ef74f6062294722c3e7cbfddaf2d7b3 333 Pfam PF00491 Arginase family 45 320 6.0E-58 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS00490 9ef74f6062294722c3e7cbfddaf2d7b3 333 Gene3D G3DSA:3.40.800.10 10 333 1.6E-66 T 29-03-2018 CB4_RS13405 a6517644deb936ad3fc96416c9b014e7 182 Gene3D G3DSA:3.40.50.360 1 181 3.6E-28 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS13405 a6517644deb936ad3fc96416c9b014e7 182 SUPERFAMILY SSF52218 7 171 1.16E-37 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS13405 a6517644deb936ad3fc96416c9b014e7 182 Pfam PF03358 NADPH-dependent FMN reductase 7 149 1.0E-31 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 Gene3D G3DSA:3.30.450.40 239 306 6.6E-6 T 29-03-2018 IPR029016 GAF domain-like CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 SUPERFAMILY SSF55781 242 384 7.63E-13 T 29-03-2018 IPR029016 GAF domain-like CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 Gene3D G3DSA:1.10.287.130 393 450 2.5E-18 T 29-03-2018 CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 Gene3D G3DSA:3.30.565.10 451 612 8.5E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 SUPERFAMILY SSF47384 373 457 5.3E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 PRINTS PR00344 Bacterial sensor protein C-terminal signature 555 565 1.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 PRINTS PR00344 Bacterial sensor protein C-terminal signature 572 590 1.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 551 1.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 PRINTS PR00344 Bacterial sensor protein C-terminal signature 596 609 1.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 SMART SM00388 388 456 8.0E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 SMART SM00387 501 612 1.7E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 SUPERFAMILY SSF55874 445 610 1.27E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 501 610 3.4E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 Pfam PF00512 His Kinase A (phospho-acceptor) domain 389 456 2.2E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS20420 6e038ec7a415af1febd028a384b10a1e 627 Gene3D G3DSA:3.30.450.40 307 392 7.8E-13 T 29-03-2018 IPR029016 GAF domain-like CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 SUPERFAMILY SSF50692 811 959 3.84E-34 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 PIRSF PIRSF036643 1 965 0.0 T 29-03-2018 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Gene3D G3DSA:2.20.25.90 264 316 4.6E-18 T 29-03-2018 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 191 202 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 SMART SM00929 84 125 1.9E-8 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Gene3D G3DSA:3.10.20.30 1 116 8.2E-12 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Gene3D G3DSA:3.40.50.740 511 784 2.7E-81 T 29-03-2018 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Gene3D G3DSA:2.40.40.20 785 934 1.8E-28 T 29-03-2018 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Gene3D G3DSA:3.40.50.740 317 510 1.1E-41 T 29-03-2018 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 259 312 7.4E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 SUPERFAMILY SSF54292 7 75 7.68E-16 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Gene3D G3DSA:3.30.70.20 117 171 0.001 T 29-03-2018 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 SUPERFAMILY SSF54862 77 212 1.93E-28 T 29-03-2018 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 263 931 4.9E-238 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 SMART SM00926 258 312 4.8E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Gene3D G3DSA:1.10.1060.10 172 263 8.3E-8 T 29-03-2018 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 86 123 2.8E-9 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Pfam PF00384 Molybdopterin oxidoreductase 315 739 1.6E-80 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Pfam PF00037 4Fe-4S binding domain 186 206 2.1E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Pfam PF01568 Molydopterin dinucleotide binding domain 821 928 6.0E-21 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 76 6.5E-12 T 29-03-2018 CB4_RS13090 df78fe6e0d357c3c78146dbae5f77614 983 SUPERFAMILY SSF53706 254 816 5.5E-190 T 29-03-2018 CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 SMART SM00304 396 456 66.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 SMART SM00304 216 274 1.9E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 SUPERFAMILY SSF58104 309 578 1.28E-68 T 29-03-2018 CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 SUPERFAMILY SSF58104 247 276 1.28E-68 T 29-03-2018 CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 364 532 6.4E-44 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 Gene3D G3DSA:3.30.450.20 29 188 8.6E-12 T 29-03-2018 CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 SUPERFAMILY SSF103190 65 180 8.63E-6 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 Gene3D G3DSA:1.10.287.950 248 336 1.3E-5 T 29-03-2018 CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 Gene3D G3DSA:1.10.287.950 337 579 5.2E-54 T 29-03-2018 CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 Pfam PF00672 HAMP domain 217 269 2.8E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS17995 f79eff540a6e8015da2702b20b30f924 579 SMART SM00283 303 578 2.3E-73 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02350 4ea304b943ea9f566c820b7a1072b4bf 386 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 1 384 51.707 T 29-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CB4_RS02350 4ea304b943ea9f566c820b7a1072b4bf 386 SUPERFAMILY SSF56059 105 307 2.3E-59 T 29-03-2018 CB4_RS02350 4ea304b943ea9f566c820b7a1072b4bf 386 SUPERFAMILY SSF51246 312 382 5.65E-13 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CB4_RS02350 4ea304b943ea9f566c820b7a1072b4bf 386 SUPERFAMILY SSF52440 4 104 1.87E-32 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS02350 4ea304b943ea9f566c820b7a1072b4bf 386 Gene3D G3DSA:3.30.1490.20 94 189 6.8E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS02350 4ea304b943ea9f566c820b7a1072b4bf 386 Pfam PF02222 ATP-grasp domain 115 286 2.6E-61 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CB4_RS02350 4ea304b943ea9f566c820b7a1072b4bf 386 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 6 383 4.6E-187 T 29-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CB4_RS02350 4ea304b943ea9f566c820b7a1072b4bf 386 Gene3D G3DSA:3.40.50.20 7 93 1.3E-20 T 29-03-2018 CB4_RS02350 4ea304b943ea9f566c820b7a1072b4bf 386 Gene3D G3DSA:3.30.470.20 190 383 6.1E-40 T 29-03-2018 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 Gene3D G3DSA:3.40.50.150 248 466 7.8E-60 T 29-03-2018 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 SUPERFAMILY SSF48013 10 162 2.22E-38 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 SUPERFAMILY SSF53335 150 459 4.26E-70 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 13 459 2.8E-133 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 267 277 9.8E-29 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 442 459 9.8E-29 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 385 401 9.8E-29 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 238 252 9.8E-29 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 335 347 9.8E-29 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 Gene3D G3DSA:3.30.70.1170 178 247 1.4E-8 T 29-03-2018 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 Pfam PF01189 16S rRNA methyltransferase RsmB/F 257 458 1.6E-61 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 334 345 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 Pfam PF01029 NusB family 11 132 4.5E-33 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CB4_RS08495 e881b3cc662bddf69ade92d831d86226 466 Gene3D G3DSA:1.10.940.10 6 152 1.2E-32 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CB4_RS16495 2b0c6321ca6ca0cecf16a19f709c7b98 177 SUPERFAMILY SSF88659 112 175 5.05E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16495 2b0c6321ca6ca0cecf16a19f709c7b98 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 175 2.2E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16495 2b0c6321ca6ca0cecf16a19f709c7b98 177 Pfam PF08281 Sigma-70, region 4 120 171 6.7E-18 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16495 2b0c6321ca6ca0cecf16a19f709c7b98 177 SUPERFAMILY SSF88946 3 102 3.53E-25 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16495 2b0c6321ca6ca0cecf16a19f709c7b98 177 Pfam PF04542 Sigma-70 region 2 23 90 4.2E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16495 2b0c6321ca6ca0cecf16a19f709c7b98 177 Gene3D G3DSA:1.10.1740.10 2 94 4.0E-23 T 29-03-2018 CB4_RS16495 2b0c6321ca6ca0cecf16a19f709c7b98 177 Gene3D G3DSA:1.10.10.10 95 177 2.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 918 21.123 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 Pfam PF06827 Zinc finger found in FPG and IleRS 887 916 1.4E-9 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 Gene3D G3DSA:1.10.730.10 633 805 2.4E-46 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 4.0E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 554 563 4.0E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 229 252 4.0E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 520 533 4.0E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 4.0E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 SUPERFAMILY SSF52374 1 201 3.58E-156 T 29-03-2018 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 SUPERFAMILY SSF52374 393 641 3.58E-156 T 29-03-2018 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 832 0.0 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 Pfam PF08264 Anticodon-binding domain of tRNA 678 833 2.1E-30 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 SUPERFAMILY SSF50677 202 393 4.5E-63 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 Gene3D G3DSA:3.90.740.10 218 376 3.4E-53 T 29-03-2018 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 26 634 7.2E-220 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 SUPERFAMILY SSF47323 645 918 3.55E-78 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 Gene3D G3DSA:3.30.2320.20 806 885 1.2E-22 T 29-03-2018 CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 Gene3D G3DSA:3.40.50.620 377 631 1.1E-79 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS08360 e9254f6b74bd6df51a27f8a183619747 922 Gene3D G3DSA:3.40.50.620 27 217 4.3E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS02175 e0061f73fcbfe775ac47e996f337bcc0 449 Gene3D G3DSA:3.40.640.10 105 319 3.1E-29 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS02175 e0061f73fcbfe775ac47e996f337bcc0 449 Gene3D G3DSA:1.10.10.10 1 68 4.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02175 e0061f73fcbfe775ac47e996f337bcc0 449 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS02175 e0061f73fcbfe775ac47e996f337bcc0 449 Pfam PF00155 Aminotransferase class I and II 94 440 4.8E-22 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS02175 e0061f73fcbfe775ac47e996f337bcc0 449 SUPERFAMILY SSF46785 2 69 1.58E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02175 e0061f73fcbfe775ac47e996f337bcc0 449 SUPERFAMILY SSF53383 63 446 1.18E-69 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS02175 e0061f73fcbfe775ac47e996f337bcc0 449 Gene3D G3DSA:3.90.1150.10 320 448 1.1E-9 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS02175 e0061f73fcbfe775ac47e996f337bcc0 449 SMART SM00345 7 66 1.4E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 Gene3D G3DSA:1.20.58.280 70 93 1.3E-9 T 29-03-2018 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 Pfam PF13414 TPR repeat 46 87 8.8E-8 T 29-03-2018 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 Gene3D G3DSA:1.25.40.10 186 221 4.6E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 Gene3D G3DSA:1.25.40.10 5 56 2.7E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 Gene3D G3DSA:1.25.40.10 155 185 2.2E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 Gene3D G3DSA:1.10.287.1110 57 69 2.0E-6 T 29-03-2018 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 SUPERFAMILY SSF48452 4 210 4.17E-40 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 Gene3D G3DSA:1.25.40.10 94 142 2.2E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 SMART SM00028 5 38 0.12 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 SMART SM00028 141 174 1.9E-7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 SMART SM00028 175 208 9.3E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 SMART SM00028 39 72 7.0E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 SMART SM00028 107 140 16.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 SMART SM00028 73 106 0.27 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 Pfam PF13371 Tetratricopeptide repeat 116 177 2.2E-9 T 29-03-2018 CB4_RS06065 bf0dcc4666d78bb8d110d7b35903ae57 221 Gene3D G3DSA:1.10.8.10 143 154 9.9E-4 T 29-03-2018 CB4_RS08905 daa37fae4fbed06c387fab6ed5b18af1 248 Pfam PF00574 Clp protease 43 184 1.5E-33 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CB4_RS08905 daa37fae4fbed06c387fab6ed5b18af1 248 PRINTS PR00127 Clp protease catalytic subunit P signature 51 71 1.3E-13 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS08905 daa37fae4fbed06c387fab6ed5b18af1 248 PRINTS PR00127 Clp protease catalytic subunit P signature 160 179 1.3E-13 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS08905 daa37fae4fbed06c387fab6ed5b18af1 248 PRINTS PR00127 Clp protease catalytic subunit P signature 82 99 1.3E-13 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS08905 daa37fae4fbed06c387fab6ed5b18af1 248 Gene3D G3DSA:3.90.226.10 8 195 2.6E-29 T 29-03-2018 CB4_RS08905 daa37fae4fbed06c387fab6ed5b18af1 248 SUPERFAMILY SSF52096 5 187 2.69E-47 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS15425 890cf665f052eaca782aaa69ea61bd50 281 Pfam PF04865 Baseplate J-like protein 104 232 1.3E-12 T 29-03-2018 IPR006949 Baseplate protein J-like CB4_RS17680 bc7dc80d6ac62d426559d8c433478e18 368 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 247 320 1.3E-10 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS17680 bc7dc80d6ac62d426559d8c433478e18 368 Pfam PF01385 Probable transposase 166 279 1.5E-25 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS17680 bc7dc80d6ac62d426559d8c433478e18 368 Pfam PF07282 Putative transposase DNA-binding domain 293 361 2.1E-23 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS17680 bc7dc80d6ac62d426559d8c433478e18 368 Pfam PF12323 Helix-turn-helix domain 1 45 6.8E-23 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CB4_RS05890 86fd7c03bb52718c939549f432350ecc 148 Hamap MF_00707 UPF0735 ACT domain-containing protein . 4 148 32.302 T 29-03-2018 IPR008310 UPF0735 ACT domain-containing protein CB4_RS05890 86fd7c03bb52718c939549f432350ecc 148 Gene3D G3DSA:3.30.70.260 67 146 1.4E-10 T 29-03-2018 CB4_RS05890 86fd7c03bb52718c939549f432350ecc 148 SUPERFAMILY SSF55021 71 144 1.22E-9 T 29-03-2018 CB4_RS05890 86fd7c03bb52718c939549f432350ecc 148 PIRSF PIRSF025624 1 148 5.9E-55 T 29-03-2018 IPR008310 UPF0735 ACT domain-containing protein CB4_RS13990 041dd6012cc250a32291331b22f68e66 244 SMART SM00257 23 66 2.2E-12 T 29-03-2018 IPR018392 LysM domain CB4_RS13990 041dd6012cc250a32291331b22f68e66 244 Gene3D G3DSA:3.90.1720.10 115 244 2.7E-36 T 29-03-2018 CB4_RS13990 041dd6012cc250a32291331b22f68e66 244 Pfam PF00877 NlpC/P60 family 137 229 7.0E-28 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CB4_RS13990 041dd6012cc250a32291331b22f68e66 244 Pfam PF01476 LysM domain 24 66 5.6E-13 T 29-03-2018 IPR018392 LysM domain CB4_RS13990 041dd6012cc250a32291331b22f68e66 244 Gene3D G3DSA:3.10.350.10 14 85 1.4E-13 T 29-03-2018 CB4_RS13990 041dd6012cc250a32291331b22f68e66 244 SUPERFAMILY SSF54001 130 243 2.35E-36 T 29-03-2018 CB4_RS13990 041dd6012cc250a32291331b22f68e66 244 SUPERFAMILY SSF54106 23 66 4.58E-10 T 29-03-2018 IPR018392 LysM domain CB4_RS18295 32e5643e6ea3cde2f0a0dbbeb3a56041 372 Gene3D G3DSA:2.20.25.10 316 352 6.8E-4 T 29-03-2018 CB4_RS18295 32e5643e6ea3cde2f0a0dbbeb3a56041 372 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 238 317 3.2E-17 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS18295 32e5643e6ea3cde2f0a0dbbeb3a56041 372 Pfam PF01385 Probable transposase 168 267 8.7E-13 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS18295 32e5643e6ea3cde2f0a0dbbeb3a56041 372 Pfam PF07282 Putative transposase DNA-binding domain 290 359 3.2E-21 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS20325 e04fc883d99954a9229fd80744d3cedc 320 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 285 9.0E-44 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS20325 e04fc883d99954a9229fd80744d3cedc 320 Gene3D G3DSA:1.10.3470.10 27 288 4.8E-38 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 Pfam PF00072 Response regulator receiver domain 8 120 1.4E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 SUPERFAMILY SSF52172 5 136 3.56E-37 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 174 228 4.1E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 SUPERFAMILY SSF46894 171 235 1.84E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 205 217 1.8E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 189 1.8E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 205 1.8E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 ProSitePatterns PS00622 LuxR-type HTH domain signature. 189 216 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 SMART SM00448 6 119 7.0E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 Gene3D G3DSA:1.10.10.10 131 238 2.4E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 Gene3D G3DSA:3.40.50.2300 5 130 3.0E-37 T 29-03-2018 CB4_RS03355 3fc7ac977db515efc10f1a1e3b5a16be 238 SMART SM00421 172 229 5.3E-28 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS14775 3221c557294491595b98b86dbb3be783 513 SUPERFAMILY SSF54791 201 297 8.32E-18 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CB4_RS14775 3221c557294491595b98b86dbb3be783 513 Pfam PF00013 KH domain 206 264 9.9E-7 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CB4_RS14775 3221c557294491595b98b86dbb3be783 513 Gene3D G3DSA:1.10.3210.10 236 455 2.1E-36 T 29-03-2018 CB4_RS14775 3221c557294491595b98b86dbb3be783 513 Gene3D G3DSA:3.30.300.20 93 235 1.0E-8 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CB4_RS14775 3221c557294491595b98b86dbb3be783 513 Hamap MF_00335 Ribonuclease Y [rny]. 5 513 26.16 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CB4_RS14775 3221c557294491595b98b86dbb3be783 513 SUPERFAMILY SSF109604 309 460 5.39E-31 T 29-03-2018 CB4_RS14775 3221c557294491595b98b86dbb3be783 513 Pfam PF12072 Domain of unknown function (DUF3552) 6 198 4.6E-69 T 29-03-2018 IPR022711 Ribonuclease Y, N-terminal CB4_RS14775 3221c557294491595b98b86dbb3be783 513 SMART SM00471 325 431 1.6E-13 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS14775 3221c557294491595b98b86dbb3be783 513 Pfam PF01966 HD domain 330 421 5.1E-18 T 29-03-2018 IPR006674 HD domain CB4_RS14775 3221c557294491595b98b86dbb3be783 513 TIGRFAM TIGR00277 HDIG: HDIG domain 325 402 4.4E-25 T 29-03-2018 IPR006675 HDIG domain CB4_RS14775 3221c557294491595b98b86dbb3be783 513 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 8 513 7.8E-246 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CB4_RS14775 3221c557294491595b98b86dbb3be783 513 SMART SM00322 201 268 9.9E-8 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 Gene3D G3DSA:1.10.601.10 7 104 2.5E-31 T 29-03-2018 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 Pfam PF04545 Sigma-70, region 4 198 246 7.3E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 PRINTS PR00046 Major sigma-70 factor signature 219 234 5.6E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 PRINTS PR00046 Major sigma-70 factor signature 202 214 5.6E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 PRINTS PR00046 Major sigma-70 factor signature 234 245 5.6E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 PRINTS PR00046 Major sigma-70 factor signature 60 73 5.6E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 PRINTS PR00046 Major sigma-70 factor signature 84 92 5.6E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 30 249 2.0E-88 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 SUPERFAMILY SSF88659 108 183 6.54E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 Pfam PF04539 Sigma-70 region 3 116 183 4.9E-13 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 Pfam PF04542 Sigma-70 region 2 36 103 6.0E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 Gene3D G3DSA:1.10.10.10 105 157 3.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 248 1.2E-37 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 SUPERFAMILY SSF88946 10 104 1.57E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 SUPERFAMILY SSF88659 170 250 8.97E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 219 245 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 PIRSF PIRSF000770 4 251 2.5E-36 T 29-03-2018 CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 Gene3D G3DSA:1.10.10.10 166 251 5.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16200 c8e1f9450ca4ce1cd986d44ee31278cd 251 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 21 249 3.2E-112 T 29-03-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09210 23bcb4542b53e1036ab85334b997e6ca 216 Pfam PF01339 CheB methylesterase 29 210 2.3E-59 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CB4_RS09210 23bcb4542b53e1036ab85334b997e6ca 216 Gene3D G3DSA:3.40.50.180 23 216 1.2E-72 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CB4_RS09210 23bcb4542b53e1036ab85334b997e6ca 216 SUPERFAMILY SSF52738 26 214 3.66E-63 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 21 519 34.078 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 Gene3D G3DSA:3.40.220.10 8 187 7.0E-35 T 29-03-2018 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 SUPERFAMILY SSF52949 19 198 1.0E-31 T 29-03-2018 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 205 511 1.6E-113 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 42 167 1.4E-23 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 Gene3D G3DSA:3.40.630.10 191 517 9.2E-124 T 29-03-2018 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 SUPERFAMILY SSF53187 202 515 6.28E-109 T 29-03-2018 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 PRINTS PR00481 Cytosol aminopeptidase signature 282 299 2.9E-46 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 PRINTS PR00481 Cytosol aminopeptidase signature 391 406 2.9E-46 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 PRINTS PR00481 Cytosol aminopeptidase signature 304 325 2.9E-46 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 PRINTS PR00481 Cytosol aminopeptidase signature 363 383 2.9E-46 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CB4_RS08100 1082a2e966bbd7c334ec558b5e15abd8 520 PRINTS PR00481 Cytosol aminopeptidase signature 341 362 2.9E-46 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CB4_RS02705 29540f82857c02abd5f7f0d2d4e2382e 431 SMART SM00471 54 185 1.1E-13 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS02705 29540f82857c02abd5f7f0d2d4e2382e 431 SUPERFAMILY SSF109604 4 413 4.89E-116 T 29-03-2018 CB4_RS02705 29540f82857c02abd5f7f0d2d4e2382e 431 Pfam PF01966 HD domain 58 177 1.5E-14 T 29-03-2018 IPR006674 HD domain CB4_RS02705 29540f82857c02abd5f7f0d2d4e2382e 431 Gene3D G3DSA:1.10.3210.10 7 310 1.3E-77 T 29-03-2018 CB4_RS01650 6a48f97541465892742f06190fb026a1 574 SMART SM00382 37 179 2.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS01650 6a48f97541465892742f06190fb026a1 574 SUPERFAMILY SSF48019 247 360 1.45E-20 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CB4_RS01650 6a48f97541465892742f06190fb026a1 574 Pfam PF13177 DNA polymerase III, delta subunit 20 177 2.7E-48 T 29-03-2018 CB4_RS01650 6a48f97541465892742f06190fb026a1 574 SUPERFAMILY SSF52540 32 222 9.42E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01650 6a48f97541465892742f06190fb026a1 574 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 359 3.9E-10 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CB4_RS01650 6a48f97541465892742f06190fb026a1 574 Gene3D G3DSA:1.20.272.10 243 363 2.4E-18 T 29-03-2018 CB4_RS01650 6a48f97541465892742f06190fb026a1 574 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 4.9E-6 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS01650 6a48f97541465892742f06190fb026a1 574 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 4.9E-6 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS01650 6a48f97541465892742f06190fb026a1 574 Gene3D G3DSA:3.40.50.300 1 166 1.8E-42 T 29-03-2018 CB4_RS01650 6a48f97541465892742f06190fb026a1 574 Gene3D G3DSA:1.10.8.60 167 242 1.5E-21 T 29-03-2018 CB4_RS01650 6a48f97541465892742f06190fb026a1 574 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 2.3E-140 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CB4_RS10130 a6f05a942e91e9ccb793fbabcb97a83a 370 SUPERFAMILY SSF53850 56 363 1.99E-45 T 29-03-2018 CB4_RS10130 a6f05a942e91e9ccb793fbabcb97a83a 370 Pfam PF13343 Bacterial extracellular solute-binding protein 107 330 1.3E-31 T 29-03-2018 CB4_RS10130 a6f05a942e91e9ccb793fbabcb97a83a 370 Gene3D G3DSA:3.40.190.10 11 192 3.2E-14 T 29-03-2018 CB4_RS10130 a6f05a942e91e9ccb793fbabcb97a83a 370 Gene3D G3DSA:3.40.190.10 193 344 1.2E-16 T 29-03-2018 CB4_RS07275 6c9d1ec176ec8b878d967e5c1efbff27 424 Pfam PF00324 Amino acid permease 11 382 3.4E-37 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CB4_RS07275 6c9d1ec176ec8b878d967e5c1efbff27 424 PIRSF PIRSF006060 1 417 5.3E-64 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS19425 bd486bc3b93475a3c22bd98a60aa189a 389 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 6 381 1.1E-69 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS19425 bd486bc3b93475a3c22bd98a60aa189a 389 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 224 380 4.3E-24 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 289 296 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Pfam PF02436 Conserved carboxylase domain 829 1029 1.6E-75 T 29-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 6 1145 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Gene3D G3DSA:3.10.600.10 464 530 4.9E-18 T 29-03-2018 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 SUPERFAMILY SSF52440 2 115 3.02E-45 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS16895 10588b1961498db2367596132cd5c442 1148 PIRSF PIRSF001594 1 1147 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Gene3D G3DSA:3.30.1490.20 127 212 1.5E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 SMART SM00878 345 452 1.2E-51 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Gene3D G3DSA:3.10.600.10 992 1062 2.2E-19 T 29-03-2018 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 SUPERFAMILY SSF89000 834 1011 8.63E-57 T 29-03-2018 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 SUPERFAMILY SSF51246 340 458 2.3E-36 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Gene3D G3DSA:2.40.50.100 1075 1147 2.0E-18 T 29-03-2018 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 SUPERFAMILY SSF51569 526 837 6.41E-85 T 29-03-2018 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 118 325 4.6E-81 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 113 3.1E-43 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Gene3D G3DSA:1.10.10.60 945 991 1.9E-20 T 29-03-2018 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Gene3D G3DSA:3.40.50.20 3 126 4.2E-51 T 29-03-2018 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Pfam PF02785 Biotin carboxylase C-terminal domain 345 452 1.8E-31 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Pfam PF00682 HMGL-like 536 806 5.1E-29 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Pfam PF00364 Biotin-requiring enzyme 1079 1145 3.9E-18 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CB4_RS16895 10588b1961498db2367596132cd5c442 1148 SUPERFAMILY SSF56059 86 332 7.25E-67 T 29-03-2018 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Gene3D G3DSA:3.30.470.20 213 454 5.7E-94 T 29-03-2018 CB4_RS16895 10588b1961498db2367596132cd5c442 1148 SUPERFAMILY SSF51230 1069 1145 3.53E-21 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS16895 10588b1961498db2367596132cd5c442 1148 Gene3D G3DSA:3.20.20.70 531 833 7.9E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS14945 acaaba2f50e1630b631e94e9133edd07 217 SUPERFAMILY SSF46785 20 91 1.97E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14945 acaaba2f50e1630b631e94e9133edd07 217 Gene3D G3DSA:1.10.10.10 16 86 1.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14945 acaaba2f50e1630b631e94e9133edd07 217 SMART SM00881 92 192 1.4E-23 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CB4_RS14945 acaaba2f50e1630b631e94e9133edd07 217 Pfam PF02629 CoA binding domain 93 191 1.2E-23 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CB4_RS14945 acaaba2f50e1630b631e94e9133edd07 217 Gene3D G3DSA:3.40.50.720 89 217 9.4E-19 T 29-03-2018 CB4_RS14945 acaaba2f50e1630b631e94e9133edd07 217 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 13 217 32.297 T 29-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CB4_RS14945 acaaba2f50e1630b631e94e9133edd07 217 Pfam PF06971 Putative DNA-binding protein N-terminus 18 64 5.3E-20 T 29-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CB4_RS14945 acaaba2f50e1630b631e94e9133edd07 217 SUPERFAMILY SSF51735 93 216 1.84E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS13940 0cb072af04c19d5f388a278b4988742f 112 Pfam PF00589 Phage integrase family 27 86 3.2E-10 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS13940 0cb072af04c19d5f388a278b4988742f 112 SUPERFAMILY SSF56349 6 95 7.36E-19 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS13940 0cb072af04c19d5f388a278b4988742f 112 Gene3D G3DSA:1.10.443.10 2 101 1.8E-16 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS14880 8829dc9038a97d7d360512d63044f893 381 Gene3D G3DSA:2.40.50.100 58 144 1.1E-13 T 29-03-2018 CB4_RS14880 8829dc9038a97d7d360512d63044f893 381 Gene3D G3DSA:2.40.50.100 225 303 2.6E-7 T 29-03-2018 CB4_RS14880 8829dc9038a97d7d360512d63044f893 381 Gene3D G3DSA:1.10.287.470 150 207 2.0E-7 T 29-03-2018 CB4_RS14880 8829dc9038a97d7d360512d63044f893 381 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 59 372 4.4E-22 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CB4_RS14880 8829dc9038a97d7d360512d63044f893 381 SUPERFAMILY SSF111369 46 137 2.48E-10 T 29-03-2018 CB4_RS14880 8829dc9038a97d7d360512d63044f893 381 SUPERFAMILY SSF111369 225 372 8.63E-16 T 29-03-2018 CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 161 240 4.5E-14 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 3.8E-43 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 SUPERFAMILY SSF54534 89 244 2.95E-34 T 29-03-2018 CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 PIRSF PIRSF003095 1 428 8.7E-134 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 Hamap MF_00303 Trigger factor [tig]. 1 428 23.221 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 424 3.0E-46 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 TIGRFAM TIGR00115 tig: trigger factor 12 424 5.8E-143 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 Gene3D G3DSA:3.30.70.1050 1 119 4.2E-38 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 SUPERFAMILY SSF102735 1 128 1.28E-38 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 SUPERFAMILY SSF109998 251 428 1.31E-45 T 29-03-2018 IPR027304 Trigger factor/SurA domain CB4_RS05605 c11db162502b2bdb5dbca8d4538abe8e 428 Gene3D G3DSA:1.10.3120.10 214 401 3.0E-56 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 622 665 1.9E-9 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 517 562 6.5E-14 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 669 715 1.9E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 771 816 6.9E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 566 615 9.2E-14 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 720 767 2.1E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Gene3D G3DSA:1.10.268.10 343 498 2.4E-44 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 483 4.3E-156 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Gene3D G3DSA:3.90.199.10 34 215 5.4E-87 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Gene3D G3DSA:2.120.10.90 510 835 5.5E-128 T 29-03-2018 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 5 818 24.386 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 SMART SM00434 11 476 2.8E-277 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 Gene3D G3DSA:3.30.1360.40 236 331 7.7E-39 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 SUPERFAMILY SSF101904 510 827 1.31E-112 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 SUPERFAMILY SSF56719 30 498 6.67E-178 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CB4_RS01880 859bedaf590b0c26d50b652405a43d54 851 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 816 0.0 T 29-03-2018 CB4_RS15575 046429531e6adc24761a62a4e968f72f 442 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 235 1.1E-12 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15575 046429531e6adc24761a62a4e968f72f 442 SUPERFAMILY SSF88946 21 95 3.77E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15575 046429531e6adc24761a62a4e968f72f 442 Gene3D G3DSA:1.10.10.60 305 333 0.0013 T 29-03-2018 CB4_RS15575 046429531e6adc24761a62a4e968f72f 442 Pfam PF04542 Sigma-70 region 2 25 95 8.1E-7 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15575 046429531e6adc24761a62a4e968f72f 442 Gene3D G3DSA:1.10.10.10 176 244 4.5E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15575 046429531e6adc24761a62a4e968f72f 442 Gene3D G3DSA:1.10.1740.10 20 95 2.3E-13 T 29-03-2018 CB4_RS15575 046429531e6adc24761a62a4e968f72f 442 SUPERFAMILY SSF46689 321 411 2.24E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS15575 046429531e6adc24761a62a4e968f72f 442 Gene3D G3DSA:1.10.10.10 334 416 5.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS01135 97dca98a5a456126fc4fa40e10b19c6f 199 Pfam PF05175 Methyltransferase small domain 27 194 1.4E-47 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CB4_RS01135 97dca98a5a456126fc4fa40e10b19c6f 199 Gene3D G3DSA:3.40.50.150 11 199 6.4E-38 T 29-03-2018 CB4_RS01135 97dca98a5a456126fc4fa40e10b19c6f 199 SUPERFAMILY SSF53335 14 196 9.65E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 SUPERFAMILY SSF53901 5 272 1.14E-93 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 Gene3D G3DSA:3.40.47.10 1 185 2.4E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 Gene3D G3DSA:3.40.47.10 186 267 3.0E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 PIRSF PIRSF000429 1 395 3.0E-140 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 393 6.5E-153 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 Pfam PF02803 Thiolase, C-terminal domain 273 393 1.6E-52 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 Gene3D G3DSA:3.40.47.10 268 392 1.1E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 SUPERFAMILY SSF53901 273 394 9.8E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS02935 4fa464e03c002f695ecd1412daf1dcbf 395 Pfam PF00108 Thiolase, N-terminal domain 6 265 3.3E-109 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CB4_RS10460 502ad3e96a254fd0d2e8d52624f88f28 294 PIRSF PIRSF006483 4 286 1.6E-86 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS10460 502ad3e96a254fd0d2e8d52624f88f28 294 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 225 279 1.2E-16 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CB4_RS10460 502ad3e96a254fd0d2e8d52624f88f28 294 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 15 219 4.9E-63 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS11810 523325d91439d220128a538e539c2c85 295 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 92 9.4E-13 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11810 523325d91439d220128a538e539c2c85 295 Gene3D G3DSA:1.10.10.10 87 139 0.0019 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS11810 523325d91439d220128a538e539c2c85 295 Gene3D G3DSA:1.10.10.60 242 282 6.3E-6 T 29-03-2018 CB4_RS11810 523325d91439d220128a538e539c2c85 295 Gene3D G3DSA:1.10.1740.10 7 86 4.2E-18 T 29-03-2018 CB4_RS11810 523325d91439d220128a538e539c2c85 295 SUPERFAMILY SSF88659 176 225 1.28E-7 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11810 523325d91439d220128a538e539c2c85 295 Pfam PF04545 Sigma-70, region 4 181 222 6.3E-7 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11810 523325d91439d220128a538e539c2c85 295 SUPERFAMILY SSF88659 98 165 3.14E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11810 523325d91439d220128a538e539c2c85 295 SUPERFAMILY SSF88946 11 92 5.65E-16 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11810 523325d91439d220128a538e539c2c85 295 Pfam PF04542 Sigma-70 region 2 19 92 1.4E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11810 523325d91439d220128a538e539c2c85 295 Gene3D G3DSA:1.10.10.10 177 229 5.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19775 7c81a5a0e6f351c28794f55a69fbf317 233 Pfam PF04647 Accessory gene regulator B 35 211 4.1E-27 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CB4_RS19775 7c81a5a0e6f351c28794f55a69fbf317 233 SMART SM00793 32 222 5.0E-5 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CB4_RS07850 5afbfda53b32a692e942ddd4efd795c0 304 Pfam PF01734 Patatin-like phospholipase 7 195 4.1E-29 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CB4_RS07850 5afbfda53b32a692e942ddd4efd795c0 304 SUPERFAMILY SSF52151 7 287 9.68E-38 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CB4_RS07850 5afbfda53b32a692e942ddd4efd795c0 304 Gene3D G3DSA:3.40.1090.10 3 213 6.0E-41 T 29-03-2018 CB4_RS05350 8e4e15f582356912c9ee7526c7a10cb7 362 Gene3D G3DSA:2.40.30.40 73 164 1.4E-34 T 29-03-2018 IPR023367 Peptidase M42, domain 2 CB4_RS05350 8e4e15f582356912c9ee7526c7a10cb7 362 SUPERFAMILY SSF53187 175 357 7.74E-73 T 29-03-2018 CB4_RS05350 8e4e15f582356912c9ee7526c7a10cb7 362 SUPERFAMILY SSF53187 10 84 7.74E-73 T 29-03-2018 CB4_RS05350 8e4e15f582356912c9ee7526c7a10cb7 362 Pfam PF05343 M42 glutamyl aminopeptidase 51 343 1.0E-113 T 29-03-2018 IPR008007 Peptidase M42 CB4_RS05350 8e4e15f582356912c9ee7526c7a10cb7 362 SUPERFAMILY SSF101821 74 183 1.68E-32 T 29-03-2018 CB4_RS05350 8e4e15f582356912c9ee7526c7a10cb7 362 PIRSF PIRSF001123 7 362 9.3E-145 T 29-03-2018 IPR008007 Peptidase M42 CB4_RS05350 8e4e15f582356912c9ee7526c7a10cb7 362 Gene3D G3DSA:3.40.630.10 166 359 1.0E-45 T 29-03-2018 CB4_RS09725 c366be9cfcb5ffd13ead081092c47acc 168 SUPERFAMILY SSF54106 120 166 1.57E-9 T 29-03-2018 IPR018392 LysM domain CB4_RS09725 c366be9cfcb5ffd13ead081092c47acc 168 Gene3D G3DSA:3.10.350.10 108 168 2.9E-14 T 29-03-2018 CB4_RS09725 c366be9cfcb5ffd13ead081092c47acc 168 SUPERFAMILY SSF54106 34 78 5.1E-11 T 29-03-2018 IPR018392 LysM domain CB4_RS09725 c366be9cfcb5ffd13ead081092c47acc 168 Gene3D G3DSA:3.10.350.10 32 80 9.9E-15 T 29-03-2018 CB4_RS09725 c366be9cfcb5ffd13ead081092c47acc 168 SMART SM00257 35 78 1.5E-14 T 29-03-2018 IPR018392 LysM domain CB4_RS09725 c366be9cfcb5ffd13ead081092c47acc 168 SMART SM00257 121 166 2.3E-12 T 29-03-2018 IPR018392 LysM domain CB4_RS09725 c366be9cfcb5ffd13ead081092c47acc 168 Pfam PF01476 LysM domain 122 166 7.7E-12 T 29-03-2018 IPR018392 LysM domain CB4_RS09725 c366be9cfcb5ffd13ead081092c47acc 168 Pfam PF01476 LysM domain 36 78 3.8E-13 T 29-03-2018 IPR018392 LysM domain CB4_RS06980 e9c3c5ab3f1cb85362d5c1b71a258dde 417 Gene3D G3DSA:3.90.1150.10 271 411 1.2E-55 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS06980 e9c3c5ab3f1cb85362d5c1b71a258dde 417 SUPERFAMILY SSF53383 2 413 8.93E-175 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS06980 e9c3c5ab3f1cb85362d5c1b71a258dde 417 PIRSF PIRSF000412 1 417 5.1E-166 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CB4_RS06980 e9c3c5ab3f1cb85362d5c1b71a258dde 417 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 219 235 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CB4_RS06980 e9c3c5ab3f1cb85362d5c1b71a258dde 417 Pfam PF00464 Serine hydroxymethyltransferase 6 380 2.0E-171 T 29-03-2018 CB4_RS06980 e9c3c5ab3f1cb85362d5c1b71a258dde 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 412 52.104 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CB4_RS06980 e9c3c5ab3f1cb85362d5c1b71a258dde 417 Gene3D G3DSA:3.40.640.10 34 270 1.1E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS02585 26efffb4abaaee7ac030d3b7325d8f7b 306 Pfam PF00892 EamA-like transporter family 155 290 7.9E-26 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS02585 26efffb4abaaee7ac030d3b7325d8f7b 306 Pfam PF00892 EamA-like transporter family 8 140 4.1E-25 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS02585 26efffb4abaaee7ac030d3b7325d8f7b 306 SUPERFAMILY SSF103481 41 143 3.27E-15 T 29-03-2018 CB4_RS02585 26efffb4abaaee7ac030d3b7325d8f7b 306 SUPERFAMILY SSF103481 191 292 5.75E-14 T 29-03-2018 CB4_RS18090 9fd9cbc4b1329767d20966b1292d4603 262 Gene3D G3DSA:1.10.12.10 220 262 4.6E-14 T 29-03-2018 IPR014748 Crontonase, C-terminal CB4_RS18090 9fd9cbc4b1329767d20966b1292d4603 262 Gene3D G3DSA:3.90.226.10 6 219 7.5E-71 T 29-03-2018 CB4_RS18090 9fd9cbc4b1329767d20966b1292d4603 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CB4_RS18090 9fd9cbc4b1329767d20966b1292d4603 262 SUPERFAMILY SSF52096 3 260 5.13E-80 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS18090 9fd9cbc4b1329767d20966b1292d4603 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 259 1.8E-60 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CB4_RS11080 535a47dbf86486f08dac26fecb2bf96b 393 Gene3D G3DSA:3.40.50.1970 2 184 4.6E-51 T 29-03-2018 CB4_RS11080 535a47dbf86486f08dac26fecb2bf96b 393 Gene3D G3DSA:1.20.1090.10 185 393 1.7E-42 T 29-03-2018 CB4_RS11080 535a47dbf86486f08dac26fecb2bf96b 393 Pfam PF00465 Iron-containing alcohol dehydrogenase 2 364 3.9E-106 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CB4_RS11080 535a47dbf86486f08dac26fecb2bf96b 393 SUPERFAMILY SSF56796 1 392 1.57E-104 T 29-03-2018 CB4_RS11080 535a47dbf86486f08dac26fecb2bf96b 393 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CB4_RS20250 2846022b8240b5517b821658957d2682 559 SMART SM00304 198 250 1.2E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS20250 2846022b8240b5517b821658957d2682 559 Gene3D G3DSA:1.20.1170.10 24 234 0.0096 T 29-03-2018 CB4_RS20250 2846022b8240b5517b821658957d2682 559 Gene3D G3DSA:1.10.287.950 302 558 7.4E-57 T 29-03-2018 CB4_RS20250 2846022b8240b5517b821658957d2682 559 Gene3D G3DSA:1.10.287.950 235 301 6.3E-6 T 29-03-2018 CB4_RS20250 2846022b8240b5517b821658957d2682 559 SMART SM00283 279 554 9.3E-73 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS20250 2846022b8240b5517b821658957d2682 559 Pfam PF00672 HAMP domain 198 246 1.4E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS20250 2846022b8240b5517b821658957d2682 559 SUPERFAMILY SSF58104 218 252 9.02E-70 T 29-03-2018 CB4_RS20250 2846022b8240b5517b821658957d2682 559 SUPERFAMILY SSF58104 285 554 9.02E-70 T 29-03-2018 CB4_RS20250 2846022b8240b5517b821658957d2682 559 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 508 4.7E-43 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 Gene3D G3DSA:1.20.5.170 198 220 1.4E-10 T 29-03-2018 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 PIRSF PIRSF500136 1 426 1.7E-146 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 414 8.8E-21 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 SUPERFAMILY SSF51735 4 189 3.76E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 PIRSF PIRSF000124 4 415 1.9E-54 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 SMART SM00984 314 415 3.7E-27 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 406 5.6E-117 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 177 2.8E-33 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 SUPERFAMILY SSF48179 198 289 3.23E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 287 9.2E-24 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 Gene3D G3DSA:3.40.50.720 221 421 2.1E-54 T 29-03-2018 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 SUPERFAMILY SSF52413 298 414 6.54E-25 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CB4_RS11225 3459d6ca615f61d21a07c489ce7a5da8 427 Gene3D G3DSA:3.40.50.720 1 195 3.6E-40 T 29-03-2018 CB4_RS11200 ab6adaede205ee8ea7cff29314ad8e54 375 Gene3D G3DSA:3.40.50.2000 185 357 1.4E-37 T 29-03-2018 CB4_RS11200 ab6adaede205ee8ea7cff29314ad8e54 375 Pfam PF13439 Glycosyltransferase Family 4 14 181 3.5E-17 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CB4_RS11200 ab6adaede205ee8ea7cff29314ad8e54 375 SUPERFAMILY SSF53756 11 374 5.14E-69 T 29-03-2018 CB4_RS11200 ab6adaede205ee8ea7cff29314ad8e54 375 Gene3D G3DSA:3.40.50.2000 1 184 1.4E-7 T 29-03-2018 CB4_RS11200 ab6adaede205ee8ea7cff29314ad8e54 375 Pfam PF00534 Glycosyl transferases group 1 191 350 2.8E-33 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 Gene3D G3DSA:1.10.275.10 1 135 8.9E-65 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 458 3.1E-239 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 Pfam PF10415 Fumarase C C-terminus 406 459 1.4E-26 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 PRINTS PR00145 Argininosuccinate lyase family signature 173 193 1.6E-5 T 29-03-2018 CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 1.6E-5 T 29-03-2018 CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 SUPERFAMILY SSF48557 3 457 6.6E-157 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 460 91.247 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 Gene3D G3DSA:1.10.40.30 413 460 1.5E-27 T 29-03-2018 CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 Pfam PF00206 Lyase 11 340 1.6E-115 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 Gene3D G3DSA:1.20.200.10 136 412 5.1E-86 T 29-03-2018 CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 9.2E-35 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 9.2E-35 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 9.2E-35 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS13960 8d8ec03934e6f823f03b2fdf124271ac 461 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 9.2E-35 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS02225 ea0a2ba63ab5eea0506c807c6625a777 230 SUPERFAMILY SSF52172 2 124 5.55E-41 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS02225 ea0a2ba63ab5eea0506c807c6625a777 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 5.9E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS02225 ea0a2ba63ab5eea0506c807c6625a777 230 SMART SM00448 4 114 1.7E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS02225 ea0a2ba63ab5eea0506c807c6625a777 230 Gene3D G3DSA:3.40.50.2300 1 121 9.5E-38 T 29-03-2018 CB4_RS02225 ea0a2ba63ab5eea0506c807c6625a777 230 Gene3D G3DSA:1.10.10.10 122 230 2.1E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02225 ea0a2ba63ab5eea0506c807c6625a777 230 Pfam PF00072 Response regulator receiver domain 6 115 2.4E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS02225 ea0a2ba63ab5eea0506c807c6625a777 230 SMART SM00862 152 228 3.1E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS02225 ea0a2ba63ab5eea0506c807c6625a777 230 SUPERFAMILY SSF46894 129 228 8.22E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS01840 48c2283dd22c5d2cdb687af4948b9bed 195 Gene3D G3DSA:3.40.50.880 1 195 3.4E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS01840 48c2283dd22c5d2cdb687af4948b9bed 195 PIRSF PIRSF005639 1 190 2.7E-75 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CB4_RS01840 48c2283dd22c5d2cdb687af4948b9bed 195 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 185 38.305 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CB4_RS01840 48c2283dd22c5d2cdb687af4948b9bed 195 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 183 6.2E-76 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CB4_RS01840 48c2283dd22c5d2cdb687af4948b9bed 195 Pfam PF01174 SNO glutamine amidotransferase family 5 187 1.6E-72 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CB4_RS01840 48c2283dd22c5d2cdb687af4948b9bed 195 SUPERFAMILY SSF52317 2 187 7.55E-54 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS01840 48c2283dd22c5d2cdb687af4948b9bed 195 ProSitePatterns PS01236 PdxT/SNO family family signature. 40 50 - T 29-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CB4_RS09945 5738dc32373f84b48f4186806a0f629f 523 SUPERFAMILY SSF55073 369 520 3.53E-45 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS09945 5738dc32373f84b48f4186806a0f629f 523 Pfam PF00990 Diguanylate cyclase, GGDEF domain 365 513 5.9E-44 T 29-03-2018 IPR000160 GGDEF domain CB4_RS09945 5738dc32373f84b48f4186806a0f629f 523 SMART SM00267 350 518 4.3E-54 T 29-03-2018 IPR000160 GGDEF domain CB4_RS09945 5738dc32373f84b48f4186806a0f629f 523 SUPERFAMILY SSF103190 186 263 8.63E-11 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS09945 5738dc32373f84b48f4186806a0f629f 523 Gene3D G3DSA:3.30.70.270 359 523 3.6E-50 T 29-03-2018 CB4_RS09945 5738dc32373f84b48f4186806a0f629f 523 Gene3D G3DSA:3.30.450.20 163 283 2.2E-20 T 29-03-2018 CB4_RS09945 5738dc32373f84b48f4186806a0f629f 523 Pfam PF02743 Cache domain 46 266 5.0E-25 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS09945 5738dc32373f84b48f4186806a0f629f 523 SUPERFAMILY SSF103190 66 181 5.23E-9 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS09945 5738dc32373f84b48f4186806a0f629f 523 Gene3D G3DSA:3.30.450.20 35 162 2.1E-13 T 29-03-2018 CB4_RS09945 5738dc32373f84b48f4186806a0f629f 523 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 363 517 5.1E-49 T 29-03-2018 IPR000160 GGDEF domain CB4_RS13240 c7998ec423b860770bf7b938cb325d1c 515 Gene3D G3DSA:1.10.287.950 370 466 3.2E-6 T 29-03-2018 CB4_RS13240 c7998ec423b860770bf7b938cb325d1c 515 Pfam PF14827 Double sensory domain of two-component sensor kinase 51 309 4.3E-10 T 29-03-2018 IPR029150 Double Cache domain 3 CB4_RS13240 c7998ec423b860770bf7b938cb325d1c 515 Pfam PF00672 HAMP domain 353 401 2.7E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS13240 c7998ec423b860770bf7b938cb325d1c 515 Gene3D G3DSA:3.30.450.20 183 311 6.2E-5 T 29-03-2018 CB4_RS13240 c7998ec423b860770bf7b938cb325d1c 515 SUPERFAMILY SSF103190 59 193 2.98E-9 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS13240 c7998ec423b860770bf7b938cb325d1c 515 Gene3D G3DSA:3.30.450.20 47 182 8.1E-12 T 29-03-2018 CB4_RS13240 c7998ec423b860770bf7b938cb325d1c 515 SMART SM00304 353 405 9.5E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS13240 c7998ec423b860770bf7b938cb325d1c 515 SUPERFAMILY SSF158472 353 404 2.88E-12 T 29-03-2018 CB4_RS00995 e7325b10f45e2f207aadd63a98c9802d 140 SMART SM01298 26 139 5.3E-50 T 29-03-2018 IPR014916 Kinase associated protein B CB4_RS00995 e7325b10f45e2f207aadd63a98c9802d 140 SUPERFAMILY SSF141251 16 138 9.02E-42 T 29-03-2018 CB4_RS00995 e7325b10f45e2f207aadd63a98c9802d 140 Pfam PF08810 Kinase associated protein B 26 137 2.0E-39 T 29-03-2018 IPR014916 Kinase associated protein B CB4_RS12245 4128533ba035d8da18255260bd36e555 509 PIRSF PIRSF001221 1 494 2.0E-79 T 29-03-2018 CB4_RS12245 4128533ba035d8da18255260bd36e555 509 Pfam PF01425 Amidase 24 483 1.3E-98 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS12245 4128533ba035d8da18255260bd36e555 509 SUPERFAMILY SSF75304 2 491 3.53E-117 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS12245 4128533ba035d8da18255260bd36e555 509 ProSitePatterns PS00571 Amidases signature. 151 182 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CB4_RS12245 4128533ba035d8da18255260bd36e555 509 Gene3D G3DSA:3.90.1300.10 1 499 1.3E-129 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR01159 DNA gyrase subunit B signature 277 295 2.6E-46 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR01159 DNA gyrase subunit B signature 347 363 2.6E-46 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR01159 DNA gyrase subunit B signature 230 243 2.6E-46 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR01159 DNA gyrase subunit B signature 647 663 2.6E-46 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR01159 DNA gyrase subunit B signature 395 409 2.6E-46 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR01159 DNA gyrase subunit B signature 512 521 2.6E-46 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR01159 DNA gyrase subunit B signature 631 643 2.6E-46 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR01159 DNA gyrase subunit B signature 30 40 2.6E-46 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR01159 DNA gyrase subunit B signature 215 230 2.6E-46 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR01159 DNA gyrase subunit B signature 409 429 2.6E-46 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 Pfam PF01751 Toprim domain 458 567 8.1E-16 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 Gene3D G3DSA:3.30.230.10 257 427 5.1E-56 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR00418 DNA topoisomerase II family signature 94 107 1.5E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR00418 DNA topoisomerase II family signature 566 578 1.5E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR00418 DNA topoisomerase II family signature 59 74 1.5E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR00418 DNA topoisomerase II family signature 610 626 1.5E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR00418 DNA topoisomerase II family signature 459 473 1.5E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR00418 DNA topoisomerase II family signature 138 152 1.5E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR00418 DNA topoisomerase II family signature 303 316 1.5E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR00418 DNA topoisomerase II family signature 528 544 1.5E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 PRINTS PR00418 DNA topoisomerase II family signature 546 563 1.5E-62 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 607 667 1.6E-28 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 ProSitePatterns PS00177 DNA topoisomerase II signature. 461 469 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 SUPERFAMILY SSF55874 30 245 3.27E-61 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 SUPERFAMILY SSF54211 257 425 1.9E-54 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 Gene3D G3DSA:3.40.50.670 440 675 5.3E-82 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 Gene3D G3DSA:3.30.565.10 42 256 1.4E-66 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 SMART SM00433 59 671 1.9E-291 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 57 207 4.8E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 SMART SM00387 55 210 1.2E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 Pfam PF00204 DNA gyrase B 257 425 9.5E-57 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10645 0470bf2cd316e9f2dcee0d8138af20ea 677 SUPERFAMILY SSF56719 438 672 5.75E-75 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CB4_RS02045 b455f757b15d2ebaf468fa3475f314a8 239 SUPERFAMILY SSF46894 131 232 5.39E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS02045 b455f757b15d2ebaf468fa3475f314a8 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 2.2E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS02045 b455f757b15d2ebaf468fa3475f314a8 239 SMART SM00862 155 231 8.6E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS02045 b455f757b15d2ebaf468fa3475f314a8 239 SUPERFAMILY SSF52172 2 125 4.7E-45 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS02045 b455f757b15d2ebaf468fa3475f314a8 239 Pfam PF00072 Response regulator receiver domain 5 114 2.0E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS02045 b455f757b15d2ebaf468fa3475f314a8 239 Gene3D G3DSA:3.40.50.2300 1 127 1.3E-39 T 29-03-2018 CB4_RS02045 b455f757b15d2ebaf468fa3475f314a8 239 SMART SM00448 3 113 1.1E-48 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS02045 b455f757b15d2ebaf468fa3475f314a8 239 Gene3D G3DSA:1.10.10.10 128 238 1.1E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS06610 ea6143c65df7d524a2632e7c6e29b96a 797 SMART SM00849 534 745 2.9E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS06610 ea6143c65df7d524a2632e7c6e29b96a 797 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 250 423 3.0E-32 T 29-03-2018 IPR004477 ComEC/Rec2-related protein CB4_RS06610 ea6143c65df7d524a2632e7c6e29b96a 797 Gene3D G3DSA:3.60.15.10 515 785 4.8E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS06610 ea6143c65df7d524a2632e7c6e29b96a 797 SUPERFAMILY SSF56281 524 788 4.06E-54 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS06610 ea6143c65df7d524a2632e7c6e29b96a 797 Pfam PF00753 Metallo-beta-lactamase superfamily 531 744 6.5E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS06610 ea6143c65df7d524a2632e7c6e29b96a 797 Pfam PF13567 Domain of unknown function (DUF4131) 30 185 7.5E-21 T 29-03-2018 IPR025405 Domain of unknown function DUF4131 CB4_RS06610 ea6143c65df7d524a2632e7c6e29b96a 797 Pfam PF03772 Competence protein 229 493 7.7E-59 T 29-03-2018 IPR004477 ComEC/Rec2-related protein CB4_RS06610 ea6143c65df7d524a2632e7c6e29b96a 797 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 136 774 1.5E-110 T 29-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CB4_RS17205 acb37c15a707c03eb342f5c6caf88420 510 Pfam PF00474 Sodium:solute symporter family 33 434 1.2E-121 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CB4_RS17205 acb37c15a707c03eb342f5c6caf88420 510 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 434 1.0E-88 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CB4_RS17205 acb37c15a707c03eb342f5c6caf88420 510 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 148 173 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CB4_RS02325 cf38c9bcf75987329610e61be7c67610 254 SMART SM00382 27 235 4.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS02325 cf38c9bcf75987329610e61be7c67610 254 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS02325 cf38c9bcf75987329610e61be7c67610 254 Gene3D G3DSA:3.40.50.300 1 254 5.7E-58 T 29-03-2018 CB4_RS02325 cf38c9bcf75987329610e61be7c67610 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 249 6.1E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CB4_RS02325 cf38c9bcf75987329610e61be7c67610 254 Pfam PF00005 ABC transporter 18 178 9.8E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS02325 cf38c9bcf75987329610e61be7c67610 254 SUPERFAMILY SSF52540 3 250 1.52E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS17940 62de44dc2104956b3b2bd74068dcc2b0 252 SUPERFAMILY SSF56784 8 214 4.37E-28 T 29-03-2018 IPR023214 HAD-like domain CB4_RS17940 62de44dc2104956b3b2bd74068dcc2b0 252 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 10 217 1.0E-31 T 29-03-2018 CB4_RS17940 62de44dc2104956b3b2bd74068dcc2b0 252 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 8 197 6.7E-17 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CB4_RS17940 62de44dc2104956b3b2bd74068dcc2b0 252 Gene3D G3DSA:3.40.50.1000 4 240 3.9E-21 T 29-03-2018 IPR023214 HAD-like domain CB4_RS17940 62de44dc2104956b3b2bd74068dcc2b0 252 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 7 237 7.3E-62 T 29-03-2018 IPR006380 Sucrose-phosphatase-like, N-terminal CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 Pfam PF00248 Aldo/keto reductase family 21 262 1.3E-54 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 SUPERFAMILY SSF51430 10 270 3.4E-98 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 Gene3D G3DSA:3.20.20.100 2 275 4.6E-105 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 PRINTS PR00069 Aldo-keto reductase signature 197 221 1.2E-48 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 PRINTS PR00069 Aldo-keto reductase signature 161 190 1.2E-48 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 PRINTS PR00069 Aldo-keto reductase signature 127 144 1.2E-48 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 PRINTS PR00069 Aldo-keto reductase signature 41 65 1.2E-48 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 PRINTS PR00069 Aldo-keto reductase signature 97 115 1.2E-48 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 PIRSF PIRSF000097 3 122 8.3E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 PIRSF PIRSF000097 117 273 2.6E-50 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 45 62 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CB4_RS12770 d70f40d4b4c60748dd2ddd37666fb31e 276 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CB4_RS08375 38af6da5ef3ce301b58260dc05224d55 182 Pfam PF00156 Phosphoribosyl transferase domain 10 153 8.9E-23 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CB4_RS08375 38af6da5ef3ce301b58260dc05224d55 182 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 7 180 38.563 T 29-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CB4_RS08375 38af6da5ef3ce301b58260dc05224d55 182 SUPERFAMILY SSF53271 7 175 1.31E-42 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CB4_RS08375 38af6da5ef3ce301b58260dc05224d55 182 Gene3D G3DSA:3.40.50.2020 3 182 1.0E-39 T 29-03-2018 CB4_RS18320 080b8711fe4939b99b49738ee7e6c1c7 314 Gene3D G3DSA:3.40.50.300 104 300 1.3E-20 T 29-03-2018 CB4_RS18320 080b8711fe4939b99b49738ee7e6c1c7 314 SUPERFAMILY SSF52540 127 271 7.06E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS18320 080b8711fe4939b99b49738ee7e6c1c7 314 SMART SM00382 157 283 0.0031 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS18320 080b8711fe4939b99b49738ee7e6c1c7 314 Pfam PF01695 IstB-like ATP binding protein 159 272 7.3E-15 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CB4_RS18320 080b8711fe4939b99b49738ee7e6c1c7 314 Pfam PF07319 Primosomal protein DnaI N-terminus 1 93 1.6E-8 T 29-03-2018 IPR009928 Primosomal DnaI, N-terminal CB4_RS20150 7c9525595ae53c37ffd27f64ad5a9deb 462 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 437 447 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CB4_RS20150 7c9525595ae53c37ffd27f64ad5a9deb 462 SUPERFAMILY SSF53335 71 454 2.55E-94 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS20150 7c9525595ae53c37ffd27f64ad5a9deb 462 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 276 454 2.7E-20 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CB4_RS20150 7c9525595ae53c37ffd27f64ad5a9deb 462 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 385 416 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site CB4_RS20150 7c9525595ae53c37ffd27f64ad5a9deb 462 Gene3D G3DSA:3.40.50.150 78 147 7.7E-11 T 29-03-2018 CB4_RS20150 7c9525595ae53c37ffd27f64ad5a9deb 462 Gene3D G3DSA:3.40.50.150 151 453 6.0E-53 T 29-03-2018 CB4_RS20150 7c9525595ae53c37ffd27f64ad5a9deb 462 Pfam PF01938 TRAM domain 7 62 7.2E-13 T 29-03-2018 IPR002792 TRAM domain CB4_RS20150 7c9525595ae53c37ffd27f64ad5a9deb 462 Gene3D G3DSA:2.40.50.140 2 77 7.0E-26 T 29-03-2018 CB4_RS20150 7c9525595ae53c37ffd27f64ad5a9deb 462 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 447 1.6E-174 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CB4_RS20150 7c9525595ae53c37ffd27f64ad5a9deb 462 SUPERFAMILY SSF50249 4 63 4.06E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS07220 fe362b9d31b8bdeaa894e54accf71791 461 Gene3D G3DSA:3.30.2290.10 6 222 1.0E-43 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CB4_RS07220 fe362b9d31b8bdeaa894e54accf71791 461 Pfam PF01523 Putative modulator of DNA gyrase 21 314 7.9E-66 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CB4_RS07220 fe362b9d31b8bdeaa894e54accf71791 461 PIRSF PIRSF004919 1 461 1.3E-123 T 29-03-2018 IPR025502 TldD CB4_RS07220 fe362b9d31b8bdeaa894e54accf71791 461 SUPERFAMILY SSF111283 7 459 2.75E-119 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CB4_RS05195 36257987a40ccf0192d39f74b0b6718f 368 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 15 368 49.84 T 29-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CB4_RS05195 36257987a40ccf0192d39f74b0b6718f 368 Gene3D G3DSA:3.20.20.70 7 367 3.1E-46 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS05195 36257987a40ccf0192d39f74b0b6718f 368 SUPERFAMILY SSF102114 24 355 7.46E-47 T 29-03-2018 CB4_RS05195 36257987a40ccf0192d39f74b0b6718f 368 SMART SM00729 64 290 0.007 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS05195 36257987a40ccf0192d39f74b0b6718f 368 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 60 365 2.4E-103 T 29-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CB4_RS05195 36257987a40ccf0192d39f74b0b6718f 368 Pfam PF04055 Radical SAM superfamily 68 230 5.6E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS05195 36257987a40ccf0192d39f74b0b6718f 368 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 17 365 6.6E-140 T 29-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CB4_RS05195 36257987a40ccf0192d39f74b0b6718f 368 PIRSF PIRSF004762 3 368 7.4E-106 T 29-03-2018 CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 SUPERFAMILY SSF52402 11 241 4.19E-58 T 29-03-2018 CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 393 438 3.0E-18 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 Pfam PF01171 PP-loop family 25 208 4.2E-60 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 SUPERFAMILY SSF56037 340 463 8.63E-22 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 Pfam PF11734 TilS substrate C-terminal domain 395 456 7.0E-15 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 SUPERFAMILY SSF82829 219 328 1.28E-14 T 29-03-2018 CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 Gene3D G3DSA:3.40.50.620 21 262 3.5E-43 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 25 212 1.3E-60 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 Gene3D G3DSA:3.50.40.10 370 465 3.8E-11 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 9 323 25.442 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CB4_RS01410 59ccc2addfb38a251bb9cf98c9aa0ff4 468 SMART SM00977 393 465 3.9E-24 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 TIGRFAM TIGR01069 mutS2: MutS2 family protein 4 786 2.4E-249 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 PIRSF PIRSF005814 1 786 1.4E-266 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 Pfam PF00488 MutS domain V 330 511 3.9E-36 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 SUPERFAMILY SSF160443 709 785 2.22E-7 T 29-03-2018 IPR002625 Smr domain CB4_RS05400 45dd931409da7dd7926248e737d959be 786 Gene3D G3DSA:1.10.1420.10 14 288 4.4E-5 T 29-03-2018 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 785 21.724 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 SMART SM00533 9 314 2.2E-35 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 SUPERFAMILY SSF52540 292 515 1.08E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05400 45dd931409da7dd7926248e737d959be 786 SMART SM00534 327 512 3.8E-75 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 409 425 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 SMART SM00463 708 786 5.2E-13 T 29-03-2018 IPR002625 Smr domain CB4_RS05400 45dd931409da7dd7926248e737d959be 786 Gene3D G3DSA:1.20.1420.10 509 705 2.4E-4 T 29-03-2018 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 Pfam PF01713 Smr domain 711 786 2.7E-15 T 29-03-2018 IPR002625 Smr domain CB4_RS05400 45dd931409da7dd7926248e737d959be 786 Gene3D G3DSA:3.40.50.300 290 508 2.0E-35 T 29-03-2018 CB4_RS05400 45dd931409da7dd7926248e737d959be 786 SUPERFAMILY SSF48334 20 287 3.27E-29 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CB4_RS20255 ff13412a518e589da3bee044e6c94901 383 SUPERFAMILY SSF81606 174 382 2.62E-10 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS20255 ff13412a518e589da3bee044e6c94901 383 SUPERFAMILY SSF52172 11 144 7.32E-12 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS20255 ff13412a518e589da3bee044e6c94901 383 SMART SM00331 169 383 2.3E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS20255 ff13412a518e589da3bee044e6c94901 383 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 196 382 7.3E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS20255 ff13412a518e589da3bee044e6c94901 383 Gene3D G3DSA:3.40.50.2300 2 143 5.4E-11 T 29-03-2018 CB4_RS20255 ff13412a518e589da3bee044e6c94901 383 Gene3D G3DSA:3.60.40.10 144 383 6.1E-26 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 Pfam PF04539 Sigma-70 region 3 124 176 2.0E-7 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 SUPERFAMILY SSF88946 8 110 1.57E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 Pfam PF04545 Sigma-70, region 4 206 253 6.4E-14 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 Gene3D G3DSA:1.10.601.10 4 110 4.0E-34 T 29-03-2018 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 5.4E-154 T 29-03-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 SUPERFAMILY SSF88659 175 257 7.66E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 257 1.6E-85 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 Gene3D G3DSA:1.10.10.10 111 163 6.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 PRINTS PR00046 Major sigma-70 factor signature 242 253 1.2E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 PRINTS PR00046 Major sigma-70 factor signature 90 98 1.2E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 PRINTS PR00046 Major sigma-70 factor signature 227 242 1.2E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 PRINTS PR00046 Major sigma-70 factor signature 66 79 1.2E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 PRINTS PR00046 Major sigma-70 factor signature 210 222 1.2E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 255 8.4E-37 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 Gene3D G3DSA:1.10.10.10 195 258 1.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 Pfam PF04542 Sigma-70 region 2 42 110 9.0E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 PIRSF PIRSF000770 9 258 2.5E-34 T 29-03-2018 CB4_RS08315 0d246ef877a4a5b6d16d72ea2615cfc0 258 SUPERFAMILY SSF88659 114 190 9.59E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS02365 2876bdb3191db970c80e5906e6363a3e 283 Gene3D G3DSA:3.20.20.410 1 283 8.0E-78 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CB4_RS02365 2876bdb3191db970c80e5906e6363a3e 283 SUPERFAMILY SSF117396 1 270 2.22E-79 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CB4_RS02365 2876bdb3191db970c80e5906e6363a3e 283 Pfam PF01904 Protein of unknown function DUF72 20 266 2.0E-57 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 1.6E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 Gene3D G3DSA:1.10.10.10 123 217 1.0E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 SUPERFAMILY SSF52172 3 131 8.54E-34 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 SMART SM00421 150 207 3.1E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 Gene3D G3DSA:3.40.50.2300 1 122 2.1E-31 T 29-03-2018 CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 SUPERFAMILY SSF46894 137 214 5.44E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 SMART SM00448 4 118 9.5E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16450 b65a2f6cc314fd75ffc306c2ae394fa4 219 Pfam PF00072 Response regulator receiver domain 6 118 6.1E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS03710 34b02907377d533097bbb0209c21c051 252 SUPERFAMILY SSF56281 1 224 2.66E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS03710 34b02907377d533097bbb0209c21c051 252 Gene3D G3DSA:3.60.15.10 1 252 8.4E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS03710 34b02907377d533097bbb0209c21c051 252 Pfam PF12706 Beta-lactamase superfamily domain 33 213 2.2E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS00405 de60a61c7853c34e5e421f3ed890b945 419 Gene3D G3DSA:3.40.50.1100 15 177 2.0E-42 T 29-03-2018 CB4_RS00405 de60a61c7853c34e5e421f3ed890b945 419 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 326 417 4.2E-28 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CB4_RS00405 de60a61c7853c34e5e421f3ed890b945 419 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 22 313 9.0E-78 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS00405 de60a61c7853c34e5e421f3ed890b945 419 SUPERFAMILY SSF53686 10 362 4.58E-101 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS00405 de60a61c7853c34e5e421f3ed890b945 419 Gene3D G3DSA:3.40.1020.10 229 419 2.1E-38 T 29-03-2018 CB4_RS00405 de60a61c7853c34e5e421f3ed890b945 419 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 48 61 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CB4_RS00405 de60a61c7853c34e5e421f3ed890b945 419 SUPERFAMILY SSF55021 336 413 1.46E-11 T 29-03-2018 CB4_RS00405 de60a61c7853c34e5e421f3ed890b945 419 TIGRFAM TIGR02079 THD1: threonine dehydratase 12 419 5.6E-201 T 29-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CB4_RS00870 9a0de32886a79820424d433106120d27 165 Pfam PF00333 Ribosomal protein S5, N-terminal domain 10 74 2.1E-33 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CB4_RS00870 9a0de32886a79820424d433106120d27 165 ProSitePatterns PS00585 Ribosomal protein S5 signature. 27 59 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CB4_RS00870 9a0de32886a79820424d433106120d27 165 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 161 1.6E-71 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CB4_RS00870 9a0de32886a79820424d433106120d27 165 Gene3D G3DSA:3.30.160.20 9 71 7.3E-32 T 29-03-2018 CB4_RS00870 9a0de32886a79820424d433106120d27 165 Pfam PF03719 Ribosomal protein S5, C-terminal domain 85 156 5.3E-32 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CB4_RS00870 9a0de32886a79820424d433106120d27 165 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 162 36.887 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CB4_RS00870 9a0de32886a79820424d433106120d27 165 SUPERFAMILY SSF54768 8 75 1.26E-25 T 29-03-2018 CB4_RS00870 9a0de32886a79820424d433106120d27 165 Gene3D G3DSA:3.30.230.10 75 165 7.8E-33 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS00870 9a0de32886a79820424d433106120d27 165 SUPERFAMILY SSF54211 79 158 2.78E-27 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS10205 3c6605b61404ed412475556da6c1080b 451 Pfam PF00395 S-layer homology domain 146 190 4.8E-15 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS10205 3c6605b61404ed412475556da6c1080b 451 Pfam PF00395 S-layer homology domain 85 128 2.1E-12 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS10205 3c6605b61404ed412475556da6c1080b 451 Pfam PF00395 S-layer homology domain 32 68 2.0E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS10205 3c6605b61404ed412475556da6c1080b 451 Gene3D G3DSA:2.60.40.1120 297 422 3.9E-5 T 29-03-2018 CB4_RS10205 3c6605b61404ed412475556da6c1080b 451 Gene3D G3DSA:2.60.40.1120 214 296 3.5E-8 T 29-03-2018 CB4_RS10205 3c6605b61404ed412475556da6c1080b 451 SUPERFAMILY SSF49452 215 292 2.55E-5 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CB4_RS10205 3c6605b61404ed412475556da6c1080b 451 Pfam PF13620 Carboxypeptidase regulatory-like domain 217 292 4.0E-7 T 29-03-2018 CB4_RS10205 3c6605b61404ed412475556da6c1080b 451 SUPERFAMILY SSF49464 298 353 7.06E-6 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CB4_RS16675 48c1082f115e3bd02c3c62c90b3117ba 178 SUPERFAMILY SSF46689 130 176 6.45E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS16675 48c1082f115e3bd02c3c62c90b3117ba 178 Gene3D G3DSA:3.40.50.2300 1 124 4.4E-35 T 29-03-2018 CB4_RS16675 48c1082f115e3bd02c3c62c90b3117ba 178 SUPERFAMILY SSF52172 4 145 1.99E-40 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS16675 48c1082f115e3bd02c3c62c90b3117ba 178 SMART SM00448 5 116 3.9E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16675 48c1082f115e3bd02c3c62c90b3117ba 178 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 156 176 7.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS16675 48c1082f115e3bd02c3c62c90b3117ba 178 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 139 156 7.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS16675 48c1082f115e3bd02c3c62c90b3117ba 178 Pfam PF02954 Bacterial regulatory protein, Fis family 132 173 3.8E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS16675 48c1082f115e3bd02c3c62c90b3117ba 178 Gene3D G3DSA:1.10.10.60 125 177 2.4E-18 T 29-03-2018 CB4_RS16675 48c1082f115e3bd02c3c62c90b3117ba 178 Pfam PF00072 Response regulator receiver domain 7 116 1.0E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS05490 82c489481d467c647b77435591601f2c 324 SMART SM00893 5 194 1.7E-43 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CB4_RS05490 82c489481d467c647b77435591601f2c 324 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 261 287 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CB4_RS05490 82c489481d467c647b77435591601f2c 324 SUPERFAMILY SSF52467 197 316 7.82E-48 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CB4_RS05490 82c489481d467c647b77435591601f2c 324 PIRSF PIRSF000089 1 321 7.9E-110 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CB4_RS05490 82c489481d467c647b77435591601f2c 324 SUPERFAMILY SSF52402 3 189 6.14E-48 T 29-03-2018 CB4_RS05490 82c489481d467c647b77435591601f2c 324 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 197 280 2.7E-34 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CB4_RS05490 82c489481d467c647b77435591601f2c 324 Gene3D G3DSA:3.40.50.620 3 190 1.4E-46 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS05490 82c489481d467c647b77435591601f2c 324 Gene3D G3DSA:3.40.50.1220 193 322 6.2E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CB4_RS05490 82c489481d467c647b77435591601f2c 324 Pfam PF01012 Electron transfer flavoprotein domain 6 172 2.4E-44 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CB4_RS06425 90aabab57cd05da4e13aa1bdf6eee142 345 Gene3D G3DSA:3.20.20.210 6 344 5.0E-97 T 29-03-2018 CB4_RS06425 90aabab57cd05da4e13aa1bdf6eee142 345 SUPERFAMILY SSF51726 6 343 2.27E-104 T 29-03-2018 CB4_RS06425 90aabab57cd05da4e13aa1bdf6eee142 345 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 7 342 47.752 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CB4_RS06425 90aabab57cd05da4e13aa1bdf6eee142 345 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 140 156 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CB4_RS06425 90aabab57cd05da4e13aa1bdf6eee142 345 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 7 341 2.5E-126 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CB4_RS06425 90aabab57cd05da4e13aa1bdf6eee142 345 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 10 340 4.8E-129 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CB4_RS06425 90aabab57cd05da4e13aa1bdf6eee142 345 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 23 32 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CB4_RS03695 46f66bb2985b3b31b40009a7f7e8d0dc 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 50.49 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CB4_RS03695 46f66bb2985b3b31b40009a7f7e8d0dc 257 SUPERFAMILY SSF51366 1 253 1.88E-84 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CB4_RS03695 46f66bb2985b3b31b40009a7f7e8d0dc 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 252 1.9E-123 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CB4_RS03695 46f66bb2985b3b31b40009a7f7e8d0dc 257 Gene3D G3DSA:3.20.20.70 4 248 2.1E-69 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS03695 46f66bb2985b3b31b40009a7f7e8d0dc 257 Pfam PF00977 Histidine biosynthesis protein 5 235 4.0E-91 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CB4_RS12375 446a380633108fd0b3fb02c7f620e1c1 424 Gene3D G3DSA:3.40.1080.10 1 176 8.6E-25 T 29-03-2018 CB4_RS12375 446a380633108fd0b3fb02c7f620e1c1 424 Gene3D G3DSA:3.40.1080.10 183 419 2.6E-59 T 29-03-2018 CB4_RS12375 446a380633108fd0b3fb02c7f620e1c1 424 SUPERFAMILY SSF100950 182 419 1.51E-62 T 29-03-2018 CB4_RS12375 446a380633108fd0b3fb02c7f620e1c1 424 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 16 172 7.5E-7 T 29-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 CB4_RS12375 446a380633108fd0b3fb02c7f620e1c1 424 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 264 417 3.4E-59 T 29-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain CB4_RS12375 446a380633108fd0b3fb02c7f620e1c1 424 SUPERFAMILY SSF100950 4 214 2.38E-29 T 29-03-2018 CB4_RS14770 718abd33ea0d123bd2aef13b902804a6 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 4.0E-40 T 29-03-2018 IPR007347 Sporulation stage V, protein S CB4_RS14770 718abd33ea0d123bd2aef13b902804a6 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 1.0E-38 T 29-03-2018 IPR007347 Sporulation stage V, protein S CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 PRINTS PR00662 Glucose-6-phosphate isomerase signature 395 409 9.1E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 PRINTS PR00662 Glucose-6-phosphate isomerase signature 409 422 9.1E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 PRINTS PR00662 Glucose-6-phosphate isomerase signature 377 395 9.1E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 PRINTS PR00662 Glucose-6-phosphate isomerase signature 274 295 9.1E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 9.1E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 9.1E-25 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 409 426 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 Gene3D G3DSA:3.40.50.10490 226 418 4.0E-52 T 29-03-2018 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 Gene3D G3DSA:3.40.50.10490 1 50 8.7E-8 T 29-03-2018 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 Pfam PF00342 Phosphoglucose isomerase 77 296 1.2E-12 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 Pfam PF00342 Phosphoglucose isomerase 374 435 4.0E-5 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 2 436 23.919 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 Gene3D G3DSA:3.40.50.10490 51 225 9.1E-50 T 29-03-2018 CB4_RS03135 790cb950300ad93f50f00ea147dfe720 442 SUPERFAMILY SSF53697 6 436 1.44E-124 T 29-03-2018 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 Pfam PF00154 recA bacterial DNA recombination protein 7 268 4.1E-146 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 Gene3D G3DSA:3.30.250.10 269 326 1.1E-25 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 SMART SM00382 57 228 2.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 SUPERFAMILY SSF52540 4 267 4.3E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 ProSitePatterns PS00321 recA signature. 213 221 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 324 7.8E-174 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 PRINTS PR00142 RecA protein signature 93 122 7.4E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 PRINTS PR00142 RecA protein signature 297 314 7.4E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 PRINTS PR00142 RecA protein signature 210 238 7.4E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 PRINTS PR00142 RecA protein signature 127 156 7.4E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 PRINTS PR00142 RecA protein signature 243 272 7.4E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 PRINTS PR00142 RecA protein signature 165 194 7.4E-86 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 Hamap MF_00268 Protein RecA [recA]. 4 329 53.139 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 SUPERFAMILY SSF54752 268 326 6.67E-22 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CB4_RS14785 8a033a6952212d6806b670fc5c118489 351 Gene3D G3DSA:3.40.50.300 25 268 1.6E-44 T 29-03-2018 CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 Pfam PF00483 Nucleotidyl transferase 6 212 2.3E-25 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 393 426 3.5E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 282 310 7.5E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 252 280 1.3E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 349 2.3E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 SUPERFAMILY SSF53448 6 305 2.48E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 Gene3D G3DSA:2.160.10.10 309 439 5.8E-36 T 29-03-2018 CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 SUPERFAMILY SSF51161 252 438 2.65E-49 T 29-03-2018 IPR011004 Trimeric LpxA-like CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 Gene3D G3DSA:2.160.10.10 244 308 3.7E-18 T 29-03-2018 CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 450 41.128 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 Gene3D G3DSA:3.90.550.10 2 243 3.6E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 451 1.8E-181 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CB4_RS01490 c79b641ff1c8289054477cc10fa1b8ee 454 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 401 429 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CB4_RS08850 ab58317c822376c98c5027cbf9fde32a 122 SUPERFAMILY SSF159006 2 120 1.44E-25 T 29-03-2018 CB4_RS08850 ab58317c822376c98c5027cbf9fde32a 122 Gene3D G3DSA:2.30.30.290 55 122 4.3E-16 T 29-03-2018 IPR023385 YopX-like domain, beta barrel type CB4_RS08850 ab58317c822376c98c5027cbf9fde32a 122 Pfam PF09643 YopX protein 38 120 7.7E-17 T 29-03-2018 IPR019096 YopX protein CB4_RS19345 c1c0864eb04b9b3e499ccf6fa32685a0 385 SUPERFAMILY SSF52374 163 373 2.34E-87 T 29-03-2018 CB4_RS19345 c1c0864eb04b9b3e499ccf6fa32685a0 385 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 21 377 51.294 T 29-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CB4_RS19345 c1c0864eb04b9b3e499ccf6fa32685a0 385 Pfam PF14306 PUA-like domain 5 155 1.1E-50 T 29-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CB4_RS19345 c1c0864eb04b9b3e499ccf6fa32685a0 385 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 6 372 3.4E-137 T 29-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CB4_RS19345 c1c0864eb04b9b3e499ccf6fa32685a0 385 Gene3D G3DSA:3.10.400.10 4 171 6.6E-61 T 29-03-2018 CB4_RS19345 c1c0864eb04b9b3e499ccf6fa32685a0 385 SUPERFAMILY SSF88697 5 159 4.67E-49 T 29-03-2018 IPR015947 PUA-like domain CB4_RS19345 c1c0864eb04b9b3e499ccf6fa32685a0 385 Gene3D G3DSA:3.40.50.620 172 373 2.4E-91 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS19345 c1c0864eb04b9b3e499ccf6fa32685a0 385 Pfam PF01747 ATP-sulfurylase 164 373 9.3E-95 T 29-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CB4_RS09050 7744873c187937c40af570f5e76edd1d 435 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 335 358 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CB4_RS09050 7744873c187937c40af570f5e76edd1d 435 Pfam PF01134 Glucose inhibited division protein A 3 365 2.1E-115 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CB4_RS09050 7744873c187937c40af570f5e76edd1d 435 Gene3D G3DSA:3.50.50.60 2 376 2.5E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS09050 7744873c187937c40af570f5e76edd1d 435 SUPERFAMILY SSF51905 3 364 3.02E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS09050 7744873c187937c40af570f5e76edd1d 435 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 2 430 6.4E-235 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CB4_RS09050 7744873c187937c40af570f5e76edd1d 435 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 4 432 37.321 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CB4_RS18380 682316978c26f0470f252f89fc398d6f 232 Pfam PF00072 Response regulator receiver domain 5 114 4.5E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS18380 682316978c26f0470f252f89fc398d6f 232 Gene3D G3DSA:3.40.50.2300 2 127 1.1E-36 T 29-03-2018 CB4_RS18380 682316978c26f0470f252f89fc398d6f 232 SUPERFAMILY SSF52172 3 125 1.08E-41 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS18380 682316978c26f0470f252f89fc398d6f 232 SMART SM00448 2 113 9.0E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS18380 682316978c26f0470f252f89fc398d6f 232 Gene3D G3DSA:1.10.10.10 128 232 1.0E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18380 682316978c26f0470f252f89fc398d6f 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 3.1E-31 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS18380 682316978c26f0470f252f89fc398d6f 232 SMART SM00862 154 230 3.4E-32 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS18380 682316978c26f0470f252f89fc398d6f 232 SUPERFAMILY SSF46894 132 231 1.98E-33 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 SUPERFAMILY SSF55785 227 340 6.98E-15 T 29-03-2018 IPR000014 PAS domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 664 703 4.4E-8 T 29-03-2018 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 SMART SM00116 10 58 2.9E-10 T 29-03-2018 IPR000644 CBS domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 SMART SM00116 74 120 0.012 T 29-03-2018 IPR000644 CBS domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 413 426 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 SUPERFAMILY SSF52540 389 633 8.75E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 SUPERFAMILY SSF46689 661 703 2.82E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Gene3D G3DSA:3.30.450.20 235 373 4.9E-18 T 29-03-2018 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Gene3D G3DSA:3.10.580.10 1 123 2.8E-25 T 29-03-2018 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 SUPERFAMILY SSF55785 117 229 3.14E-14 T 29-03-2018 IPR000014 PAS domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 SMART SM00382 409 553 5.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Gene3D G3DSA:1.10.10.60 658 704 2.8E-7 T 29-03-2018 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Pfam PF00158 Sigma-54 interaction domain 389 557 4.9E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Pfam PF00989 PAS fold 129 228 2.4E-13 T 29-03-2018 IPR013767 PAS fold GO:0006355 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Pfam PF00989 PAS fold 247 318 1.2E-10 T 29-03-2018 IPR013767 PAS fold GO:0006355 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 SMART SM00091 128 194 2.1E-9 T 29-03-2018 IPR000014 PAS domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 SMART SM00091 246 313 1.5E-9 T 29-03-2018 IPR000014 PAS domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Pfam PF00571 CBS domain 3 56 1.2E-12 T 29-03-2018 IPR000644 CBS domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Pfam PF00571 CBS domain 67 119 3.2E-7 T 29-03-2018 IPR000644 CBS domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 602 611 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 129 234 2.8E-10 T 29-03-2018 IPR000014 PAS domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 248 362 1.7E-12 T 29-03-2018 IPR000014 PAS domain CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Gene3D G3DSA:3.40.50.300 383 561 2.6E-25 T 29-03-2018 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Gene3D G3DSA:3.30.450.20 124 234 1.9E-17 T 29-03-2018 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 Gene3D G3DSA:1.10.8.60 563 634 2.0E-20 T 29-03-2018 CB4_RS08120 6116d455b7a3aa694e9955d7d07fa287 710 SUPERFAMILY SSF54631 1 119 9.73E-26 T 29-03-2018 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 SUPERFAMILY SSF53850 35 353 1.24E-95 T 29-03-2018 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 Pfam PF13416 Bacterial extracellular solute-binding protein 49 316 3.9E-39 T 29-03-2018 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 Gene3D G3DSA:3.40.190.10 152 307 8.3E-42 T 29-03-2018 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 Gene3D G3DSA:3.40.190.10 22 151 1.8E-29 T 29-03-2018 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PIRSF PIRSF019574 1 356 6.3E-132 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 2.9E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 2.9E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 2.9E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 56 77 2.9E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 56 2.9E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 211 230 2.9E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 2.9E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 2.9E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 2.9E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS13725 c06c4f9d5201149a9b02b31fcc078701 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 2.9E-56 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CB4_RS02580 f78ffb47001ba2431e86c94e34ecd96a 93 Gene3D G3DSA:2.60.300.12 1 93 5.3E-12 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CB4_RS02580 f78ffb47001ba2431e86c94e34ecd96a 93 SUPERFAMILY SSF89360 1 76 2.75E-9 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CB4_RS02580 f78ffb47001ba2431e86c94e34ecd96a 93 PIRSF PIRSF034852 1 93 9.1E-33 T 29-03-2018 IPR008326 Uncharacterised conserved protein UCP034852 CB4_RS02580 f78ffb47001ba2431e86c94e34ecd96a 93 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 92 1.2E-7 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CB4_RS07905 2fd313feae471cbb18e675edfc5aec02 129 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 28 127 4.3E-38 T 29-03-2018 IPR014211 Stage III sporulation protein AD CB4_RS07905 2fd313feae471cbb18e675edfc5aec02 129 Pfam PF06686 Stage III sporulation protein AC/AD protein family 71 126 2.9E-19 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CB4_RS07905 2fd313feae471cbb18e675edfc5aec02 129 Pfam PF06686 Stage III sporulation protein AC/AD protein family 3 57 9.6E-13 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CB4_RS00840 f596f6da23b20ab64c08e642e9b27b56 72 Gene3D G3DSA:2.40.50.140 1 72 4.5E-39 T 29-03-2018 CB4_RS00840 f596f6da23b20ab64c08e642e9b27b56 72 SMART SM00316 4 72 4.9E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS00840 f596f6da23b20ab64c08e642e9b27b56 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.678 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CB4_RS00840 f596f6da23b20ab64c08e642e9b27b56 72 SUPERFAMILY SSF50249 1 71 1.59E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS00840 f596f6da23b20ab64c08e642e9b27b56 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 3.1E-29 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CB4_RS00840 f596f6da23b20ab64c08e642e9b27b56 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 5.6E-40 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CB4_RS04270 5fde556cb4d15cfa222801defea90adb 182 PIRSF PIRSF015617 1 182 3.1E-62 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CB4_RS04270 5fde556cb4d15cfa222801defea90adb 182 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 182 9.1E-59 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CB4_RS04270 5fde556cb4d15cfa222801defea90adb 182 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 6 182 7.2E-51 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CB4_RS04270 5fde556cb4d15cfa222801defea90adb 182 SUPERFAMILY SSF52540 5 182 7.12E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS04270 5fde556cb4d15cfa222801defea90adb 182 Gene3D G3DSA:3.40.50.300 1 182 1.3E-64 T 29-03-2018 CB4_RS01475 eef67da89d1fb995e355eda80b1f4ff0 73 ProDom PD057826 YABK 5 67 1.0E-8 T 29-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 CB4_RS01475 eef67da89d1fb995e355eda80b1f4ff0 73 Pfam PF10955 Protein of unknown function (DUF2757) 1 68 2.3E-18 T 29-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 CB4_RS01705 42f04c324ab9540c72c05637a13eed7a 320 Gene3D G3DSA:2.60.120.10 155 293 2.3E-10 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS01705 42f04c324ab9540c72c05637a13eed7a 320 SUPERFAMILY SSF51182 169 242 3.71E-10 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS14220 cc73e16c38d9fed4bd397e6fcdd910e1 261 SUPERFAMILY SSF53335 2 247 1.18E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS14220 cc73e16c38d9fed4bd397e6fcdd910e1 261 Gene3D G3DSA:3.40.50.150 67 249 3.3E-22 T 29-03-2018 CB4_RS14220 cc73e16c38d9fed4bd397e6fcdd910e1 261 Pfam PF04445 Putative SAM-dependent methyltransferase 78 231 2.0E-12 T 29-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 CB4_RS00860 a6bbd4464aefaca1829f09305ec62dd2 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 2.5E-38 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CB4_RS00860 a6bbd4464aefaca1829f09305ec62dd2 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.586 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CB4_RS00860 a6bbd4464aefaca1829f09305ec62dd2 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00860 a6bbd4464aefaca1829f09305ec62dd2 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 1.1E-54 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00860 a6bbd4464aefaca1829f09305ec62dd2 146 Gene3D G3DSA:3.100.10.10 42 146 6.3E-31 T 29-03-2018 CB4_RS00860 a6bbd4464aefaca1829f09305ec62dd2 146 SUPERFAMILY SSF52080 4 143 4.32E-51 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CB4_RS02505 61ef312ec37beaed3b10d678e59c7c1f 117 Gene3D G3DSA:2.60.120.10 10 113 1.1E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS02505 61ef312ec37beaed3b10d678e59c7c1f 117 Pfam PF07883 Cupin domain 44 106 1.0E-8 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CB4_RS02505 61ef312ec37beaed3b10d678e59c7c1f 117 SUPERFAMILY SSF51182 10 107 3.0E-13 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS08910 19a482fdeaac1196fc201d2aeaec3693 379 Gene3D G3DSA:3.30.2400.10 145 320 7.4E-6 T 29-03-2018 CB4_RS08910 19a482fdeaac1196fc201d2aeaec3693 379 SUPERFAMILY SSF56563 115 376 2.48E-31 T 29-03-2018 CB4_RS08910 19a482fdeaac1196fc201d2aeaec3693 379 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 7 374 5.8E-30 T 29-03-2018 IPR024455 Phage capsid CB4_RS08910 19a482fdeaac1196fc201d2aeaec3693 379 Pfam PF05065 Phage capsid family 123 374 2.0E-13 T 29-03-2018 IPR024455 Phage capsid CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 Pfam PF00072 Response regulator receiver domain 7 118 1.3E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 SUPERFAMILY SSF52172 4 132 2.85E-34 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 Gene3D G3DSA:3.40.50.2300 4 129 3.3E-34 T 29-03-2018 CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 Gene3D G3DSA:1.10.10.10 130 227 3.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 216 7.8E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 SMART SM00448 5 118 1.9E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 3.1E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 3.1E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 3.1E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 SMART SM00421 160 217 5.5E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS01810 5805f591a4d2d80504e5a95142158a6d 228 SUPERFAMILY SSF46894 151 222 7.14E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 2.1E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 2.1E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 163 180 2.1E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 2.1E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 2.1E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 2.1E-43 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 Pfam PF02110 Hydroxyethylthiazole kinase family 11 254 6.1E-94 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 PIRSF PIRSF000513 4 266 1.2E-96 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 11 257 4.1E-97 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 Gene3D G3DSA:3.40.1190.20 1 266 1.4E-55 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 SUPERFAMILY SSF53613 6 261 2.36E-59 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS10635 690df5d5adc521fe5aa644a841979ce5 266 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 258 33.917 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS12035 57adfdfc6da803008b250d79fc0b2260 350 SUPERFAMILY SSF47240 12 310 7.03E-71 T 29-03-2018 IPR009078 Ferritin-like superfamily CB4_RS12035 57adfdfc6da803008b250d79fc0b2260 350 Gene3D G3DSA:1.10.620.20 9 327 6.0E-78 T 29-03-2018 CB4_RS12035 57adfdfc6da803008b250d79fc0b2260 350 Pfam PF02332 Methane/Phenol/Toluene Hydroxylase 52 275 1.6E-53 T 29-03-2018 IPR003430 Methane/phenol/toluene hydroxylase GO:0006725|GO:0055114 CB4_RS12035 57adfdfc6da803008b250d79fc0b2260 350 PIRSF PIRSF000040 2 337 4.6E-66 T 29-03-2018 IPR012078 Methane/phenol monooxygenase, hydroxylase component GO:0016709|GO:0055114 CB4_RS02000 7a1ceb9d7bd60081dfc04949e1c1e97c 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 29-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 CB4_RS02000 7a1ceb9d7bd60081dfc04949e1c1e97c 96 Pfam PF01250 Ribosomal protein S6 3 92 1.0E-33 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02000 7a1ceb9d7bd60081dfc04949e1c1e97c 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 24.352 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CB4_RS02000 7a1ceb9d7bd60081dfc04949e1c1e97c 96 SUPERFAMILY SSF54995 1 95 1.57E-36 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02000 7a1ceb9d7bd60081dfc04949e1c1e97c 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 5.0E-35 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02000 7a1ceb9d7bd60081dfc04949e1c1e97c 96 Gene3D G3DSA:3.30.70.60 2 96 1.2E-34 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CB4_RS18150 832a9ca573121adf31c93410a2d62519 587 Pfam PF13667 ThiC-associated domain 11 87 9.0E-32 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CB4_RS18150 832a9ca573121adf31c93410a2d62519 587 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 129 553 1.8E-222 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CB4_RS18150 832a9ca573121adf31c93410a2d62519 587 Pfam PF01964 Radical SAM ThiC family 130 550 2.9E-205 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CB4_RS18150 832a9ca573121adf31c93410a2d62519 587 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 129 556 57.108 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CB4_RS00060 f25904bd19a0abafbc2841c293b89c75 115 Gene3D G3DSA:3.30.429.10 2 101 1.2E-22 T 29-03-2018 CB4_RS00060 f25904bd19a0abafbc2841c293b89c75 115 Pfam PF08921 Domain of unknown function (DUF1904) 1 101 2.4E-21 T 29-03-2018 IPR015017 Protein of unknown function DUF1904 CB4_RS00060 f25904bd19a0abafbc2841c293b89c75 115 SUPERFAMILY SSF55331 1 100 1.28E-17 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CB4_RS17795 e75ef158f10d3863554865e30aed498a 235 SUPERFAMILY SSF53335 16 204 2.71E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS17795 e75ef158f10d3863554865e30aed498a 235 Gene3D G3DSA:3.40.50.150 31 223 8.6E-31 T 29-03-2018 CB4_RS17795 e75ef158f10d3863554865e30aed498a 235 Pfam PF08241 Methyltransferase domain 58 149 3.2E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CB4_RS08365 75be71f4805908f70a7e1c51e905f3cf 154 Pfam PF01252 Signal peptidase (SPase) II 6 142 1.8E-42 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CB4_RS08365 75be71f4805908f70a7e1c51e905f3cf 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 4.1E-18 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CB4_RS08365 75be71f4805908f70a7e1c51e905f3cf 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 123 139 4.1E-18 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CB4_RS08365 75be71f4805908f70a7e1c51e905f3cf 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 4.1E-18 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CB4_RS08365 75be71f4805908f70a7e1c51e905f3cf 154 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 148 16.716 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CB4_RS08365 75be71f4805908f70a7e1c51e905f3cf 154 TIGRFAM TIGR00077 lspA: signal peptidase II 2 144 3.4E-45 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CB4_RS08365 75be71f4805908f70a7e1c51e905f3cf 154 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CB4_RS01480 1dea9f93dabb4dfebe17449da2cf06e0 187 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CB4_RS01480 1dea9f93dabb4dfebe17449da2cf06e0 187 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 186 5.4E-68 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CB4_RS01480 1dea9f93dabb4dfebe17449da2cf06e0 187 Gene3D G3DSA:3.40.50.1470 1 187 6.6E-73 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CB4_RS01480 1dea9f93dabb4dfebe17449da2cf06e0 187 SUPERFAMILY SSF53178 1 186 2.22E-67 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CB4_RS01480 1dea9f93dabb4dfebe17449da2cf06e0 187 Pfam PF01195 Peptidyl-tRNA hydrolase 3 186 2.5E-60 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CB4_RS01480 1dea9f93dabb4dfebe17449da2cf06e0 187 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 179 36.814 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CB4_RS01480 1dea9f93dabb4dfebe17449da2cf06e0 187 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 108 118 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CB4_RS14895 9b6c217e0e6fb66b8c7efbe2c9e9460d 373 Pfam PF02163 Peptidase family M50 137 175 6.0E-7 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CB4_RS10975 2702b5aa4db2aace5c40242174f26660 192 Gene3D G3DSA:2.30.110.10 1 134 6.4E-15 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS10975 2702b5aa4db2aace5c40242174f26660 192 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 99 8.4E-8 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CB4_RS10975 2702b5aa4db2aace5c40242174f26660 192 SUPERFAMILY SSF50475 8 130 1.05E-7 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS00420 64118257cef59f09c262aca0d3d3e82c 258 Pfam PF13531 Bacterial extracellular solute-binding protein 37 258 4.1E-54 T 29-03-2018 CB4_RS00420 64118257cef59f09c262aca0d3d3e82c 258 Gene3D G3DSA:3.40.190.10 29 128 9.6E-20 T 29-03-2018 CB4_RS00420 64118257cef59f09c262aca0d3d3e82c 258 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 40 257 3.2E-69 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CB4_RS00420 64118257cef59f09c262aca0d3d3e82c 258 PIRSF PIRSF004846 1 258 1.6E-86 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CB4_RS00420 64118257cef59f09c262aca0d3d3e82c 258 SUPERFAMILY SSF53850 34 258 1.73E-68 T 29-03-2018 CB4_RS00420 64118257cef59f09c262aca0d3d3e82c 258 Gene3D G3DSA:3.40.190.10 129 221 9.1E-36 T 29-03-2018 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 10 312 1.5E-138 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 55 74 4.7E-28 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 4.7E-28 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 277 300 4.7E-28 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 137 148 4.7E-28 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 SUPERFAMILY SSF53671 7 313 2.62E-114 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 86 99 1.2E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 53 67 1.2E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 126 140 1.2E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 1.2E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 291 302 1.2E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 55 62 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 9 313 83.784 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 Gene3D G3DSA:3.40.50.1370 1 149 6.6E-58 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 Gene3D G3DSA:3.40.50.1370 150 312 1.8E-64 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 10 150 4.6E-51 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CB4_RS03570 83f27f972f82402fddcef5c49fde2671 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 310 1.8E-63 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 SMART SM00859 8 123 1.2E-44 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 Gene3D G3DSA:3.30.360.10 143 325 6.4E-75 T 29-03-2018 CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 8 343 3.4E-150 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 SUPERFAMILY SSF51735 7 158 1.77E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 142 328 2.9E-57 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 6 342 38.769 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 Gene3D G3DSA:3.40.50.720 3 142 1.8E-34 T 29-03-2018 CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 122 6.5E-34 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 239 253 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 SUPERFAMILY SSF55347 131 329 1.62E-75 T 29-03-2018 CB4_RS09440 c6fabf4931bb68554491e7a72849948b 347 PIRSF PIRSF000148 6 347 1.1E-133 T 29-03-2018 CB4_RS05065 60f9ff30cf4ee27f13c8563327389074 162 ProSitePatterns PS00893 Nudix box signature. 58 79 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CB4_RS05065 60f9ff30cf4ee27f13c8563327389074 162 Gene3D G3DSA:3.90.79.10 16 133 2.5E-19 T 29-03-2018 CB4_RS05065 60f9ff30cf4ee27f13c8563327389074 162 PRINTS PR00502 NUDIX hydrolase family signature 53 67 1.3E-9 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CB4_RS05065 60f9ff30cf4ee27f13c8563327389074 162 PRINTS PR00502 NUDIX hydrolase family signature 67 82 1.3E-9 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CB4_RS05065 60f9ff30cf4ee27f13c8563327389074 162 Pfam PF00293 NUDIX domain 30 84 1.7E-14 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CB4_RS05065 60f9ff30cf4ee27f13c8563327389074 162 SUPERFAMILY SSF55811 20 91 3.66E-21 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CB4_RS09270 7e1a830062c7aacba9d6a013b93a1b4c 240 SUPERFAMILY SSF53633 5 238 2.36E-72 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS09270 7e1a830062c7aacba9d6a013b93a1b4c 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.124 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CB4_RS09270 7e1a830062c7aacba9d6a013b93a1b4c 240 Gene3D G3DSA:3.40.1160.10 1 239 1.9E-45 T 29-03-2018 CB4_RS09270 7e1a830062c7aacba9d6a013b93a1b4c 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 238 1.8E-101 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CB4_RS09270 7e1a830062c7aacba9d6a013b93a1b4c 240 PIRSF PIRSF005650 1 240 8.9E-96 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CB4_RS09270 7e1a830062c7aacba9d6a013b93a1b4c 240 Pfam PF00696 Amino acid kinase family 7 217 7.6E-28 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS18625 a8ca8919e676df379b97698b6557d401 232 SUPERFAMILY SSF51206 16 152 6.42E-38 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CB4_RS18625 a8ca8919e676df379b97698b6557d401 232 Gene3D G3DSA:2.60.120.10 11 154 3.5E-39 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS18625 a8ca8919e676df379b97698b6557d401 232 SUPERFAMILY SSF46785 156 224 4.41E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18625 a8ca8919e676df379b97698b6557d401 232 SMART SM00100 22 139 9.1E-27 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS18625 a8ca8919e676df379b97698b6557d401 232 Pfam PF00027 Cyclic nucleotide-binding domain 41 125 8.1E-25 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS18625 a8ca8919e676df379b97698b6557d401 232 Gene3D G3DSA:1.10.10.10 155 232 7.3E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 SUPERFAMILY SSF55931 107 442 4.22E-126 T 29-03-2018 CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 99 6.6E-32 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 SUPERFAMILY SSF54368 5 104 9.16E-35 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 Gene3D G3DSA:3.10.20.70 2 104 2.4E-37 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 Gene3D G3DSA:3.30.590.10 105 443 5.5E-126 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 SMART SM01230 105 354 2.0E-138 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 2.6E-137 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 442 3.3E-178 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS14085 d171544c0cf29e0fec11e071c110f24d 443 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 Pfam PF00364 Biotin-requiring enzyme 3 75 1.2E-22 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 Gene3D G3DSA:4.10.320.10 120 171 5.0E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 197 427 4.3E-89 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 Gene3D G3DSA:3.30.559.10 184 427 9.9E-92 T 29-03-2018 CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 SUPERFAMILY SSF47005 112 156 9.68E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 Gene3D G3DSA:2.40.50.100 46 119 3.6E-9 T 29-03-2018 CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 SUPERFAMILY SSF52777 189 427 1.87E-89 T 29-03-2018 CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 SUPERFAMILY SSF51230 2 89 3.01E-25 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 Gene3D G3DSA:3.90.1170.30 1 45 1.2E-12 T 29-03-2018 CB4_RS19740 27c643a05c4cfb8ad459f805b2358a09 430 Pfam PF02817 e3 binding domain 118 151 7.2E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS06630 28d4ec852a2fa55faddffef6e69030f7 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 15 88 2.0E-13 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS06630 28d4ec852a2fa55faddffef6e69030f7 88 Gene3D G3DSA:1.20.58.110 1 88 1.0E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS06630 28d4ec852a2fa55faddffef6e69030f7 88 SUPERFAMILY SSF46992 3 86 2.35E-29 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS06630 28d4ec852a2fa55faddffef6e69030f7 88 Pfam PF01649 Ribosomal protein S20 2 84 2.7E-26 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS06630 28d4ec852a2fa55faddffef6e69030f7 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.519 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS06630 28d4ec852a2fa55faddffef6e69030f7 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 4.9E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01405 2067b47b61ae779fe0824860a7f91636 178 Pfam PF00156 Phosphoribosyl transferase domain 9 159 2.0E-29 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CB4_RS01405 2067b47b61ae779fe0824860a7f91636 178 Gene3D G3DSA:3.40.50.2020 1 178 8.9E-48 T 29-03-2018 CB4_RS01405 2067b47b61ae779fe0824860a7f91636 178 SUPERFAMILY SSF53271 2 177 1.84E-59 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CB4_RS01405 2067b47b61ae779fe0824860a7f91636 178 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 4.0E-67 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CB4_RS13815 8eaa0c0a425a512faa2f8a0beaa33cce 238 SUPERFAMILY SSF50685 162 214 3.84E-5 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CB4_RS13815 8eaa0c0a425a512faa2f8a0beaa33cce 238 Pfam PF06725 3D domain 171 228 3.2E-12 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CB4_RS13815 8eaa0c0a425a512faa2f8a0beaa33cce 238 Gene3D G3DSA:2.40.40.10 68 230 1.1E-29 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CB4_RS10215 921ce12dc2528f149ee621aecce4ca87 327 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 20 192 5.4E-39 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CB4_RS10215 921ce12dc2528f149ee621aecce4ca87 327 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 244 318 2.3E-13 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CB4_RS10215 921ce12dc2528f149ee621aecce4ca87 327 SUPERFAMILY SSF90002 242 317 3.79E-13 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CB4_RS10215 921ce12dc2528f149ee621aecce4ca87 327 SMART SM00833 233 320 8.5E-11 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CB4_RS10215 921ce12dc2528f149ee621aecce4ca87 327 SUPERFAMILY SSF52540 16 192 5.57E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10215 921ce12dc2528f149ee621aecce4ca87 327 Gene3D G3DSA:3.40.50.300 14 213 1.6E-27 T 29-03-2018 CB4_RS10215 921ce12dc2528f149ee621aecce4ca87 327 Gene3D G3DSA:3.30.1220.10 215 321 7.3E-12 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CB4_RS07770 fa072cfc42c6aa16d7a03a0e0eacc949 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 241 1.7E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS07770 fa072cfc42c6aa16d7a03a0e0eacc949 256 SUPERFAMILY SSF161098 3 254 1.4E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS07770 fa072cfc42c6aa16d7a03a0e0eacc949 256 Gene3D G3DSA:1.10.3720.10 1 244 6.0E-41 T 29-03-2018 CB4_RS06145 c810e4ee82fe4a9147706d853370b555 231 Gene3D G3DSA:1.20.144.10 37 230 1.1E-31 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS06145 c810e4ee82fe4a9147706d853370b555 231 SUPERFAMILY SSF48317 31 217 7.85E-40 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS06145 c810e4ee82fe4a9147706d853370b555 231 SMART SM00014 103 216 9.2E-24 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS06145 c810e4ee82fe4a9147706d853370b555 231 Pfam PF01569 PAP2 superfamily 104 216 2.1E-20 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS15585 64f374568f84df43a7ad31044215d656 292 Pfam PF09681 N-terminal phage replisome organiser (Phage_rep_org_N) 6 126 3.5E-41 T 29-03-2018 IPR010056 Phage replisome organiser, N-terminal domain CB4_RS15585 64f374568f84df43a7ad31044215d656 292 TIGRFAM TIGR01714 phage_rep_org_N: phage replisome organizer, putative, N-terminal region 6 126 3.6E-36 T 29-03-2018 IPR010056 Phage replisome organiser, N-terminal domain CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 Pfam PF02589 LUD domain 71 294 2.5E-55 T 29-03-2018 IPR003741 LUD domain CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 Gene3D G3DSA:1.10.1060.10 289 397 6.5E-15 T 29-03-2018 CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 Pfam PF11870 Domain of unknown function (DUF3390) 394 467 1.1E-7 T 29-03-2018 IPR024569 4Fe-4S binding protein, C-terminal CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 SUPERFAMILY SSF100950 135 295 1.13E-41 T 29-03-2018 CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 SUPERFAMILY SSF100950 64 89 1.13E-41 T 29-03-2018 CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 Gene3D G3DSA:3.40.50.10420 138 288 2.1E-47 T 29-03-2018 CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 Gene3D G3DSA:3.40.50.10420 63 137 2.7E-6 T 29-03-2018 CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 455 2.8E-168 T 29-03-2018 IPR004452 4Fe-4S binding protein GO:0019516 CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 Pfam PF13183 4Fe-4S dicluster domain 310 378 1.3E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 313 324 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS04205 b586e1cf263295e73a2d123bbc99304f 499 SUPERFAMILY SSF46548 270 396 4.71E-18 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CB4_RS12220 298bb4a1a35791e5e42c4933eff33825 654 Gene3D G3DSA:3.40.50.980 273 430 9.1E-20 T 29-03-2018 CB4_RS12220 298bb4a1a35791e5e42c4933eff33825 654 Gene3D G3DSA:3.30.300.30 519 623 1.4E-8 T 29-03-2018 CB4_RS12220 298bb4a1a35791e5e42c4933eff33825 654 Pfam PF00501 AMP-binding enzyme 106 525 2.3E-46 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS12220 298bb4a1a35791e5e42c4933eff33825 654 Gene3D G3DSA:3.40.50.980 92 272 1.0E-33 T 29-03-2018 CB4_RS12220 298bb4a1a35791e5e42c4933eff33825 654 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS12220 298bb4a1a35791e5e42c4933eff33825 654 SUPERFAMILY SSF56801 25 625 8.5E-120 T 29-03-2018 CB4_RS12220 298bb4a1a35791e5e42c4933eff33825 654 Pfam PF13193 AMP-binding enzyme C-terminal domain 559 612 2.6E-5 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS12220 298bb4a1a35791e5e42c4933eff33825 654 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 41 96 3.5E-10 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CB4_RS12220 298bb4a1a35791e5e42c4933eff33825 654 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 9 650 1.5E-249 T 29-03-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 CB4_RS12920 9853be015baac930a9d094d9611e546e 431 SMART SM00382 35 218 6.5E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS12920 9853be015baac930a9d094d9611e546e 431 Gene3D G3DSA:3.40.50.300 2 430 3.8E-61 T 29-03-2018 CB4_RS12920 9853be015baac930a9d094d9611e546e 431 Pfam PF00005 ABC transporter 26 165 6.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS12920 9853be015baac930a9d094d9611e546e 431 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS12920 9853be015baac930a9d094d9611e546e 431 Pfam PF09821 C-terminal AAA-associated domain 297 414 5.2E-40 T 29-03-2018 IPR018632 C-terminal AAA-associated domain CB4_RS12920 9853be015baac930a9d094d9611e546e 431 SUPERFAMILY SSF52540 6 243 4.32E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15210 a7cc58b2a93c77456f5b03481797cad3 119 Gene3D G3DSA:3.10.20.30 1 115 1.0E-25 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS15210 a7cc58b2a93c77456f5b03481797cad3 119 SUPERFAMILY SSF54292 2 91 1.21E-21 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CB4_RS15210 a7cc58b2a93c77456f5b03481797cad3 119 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 83 9.1E-13 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 309 466 1.5E-38 T 29-03-2018 IPR000160 GGDEF domain CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 SMART SM00086 91 133 8.8E-9 T 29-03-2018 IPR001610 PAC motif CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 Pfam PF00563 EAL domain 486 720 3.1E-74 T 29-03-2018 IPR001633 EAL domain CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 SMART SM00267 301 469 4.6E-49 T 29-03-2018 IPR000160 GGDEF domain CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 SMART SM00052 479 725 1.4E-113 T 29-03-2018 IPR001633 EAL domain CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 SMART SM00065 155 309 3.7E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 PIRSF PIRSF005925 9 737 5.8E-176 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 Gene3D G3DSA:3.20.20.450 477 738 1.6E-97 T 29-03-2018 IPR001633 EAL domain CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 SUPERFAMILY SSF55073 318 470 1.26E-44 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 Gene3D G3DSA:3.30.450.20 15 138 1.1E-24 T 29-03-2018 CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 38 140 1.3E-18 T 29-03-2018 IPR000014 PAS domain CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 SUPERFAMILY SSF141868 485 730 6.54E-88 T 29-03-2018 IPR001633 EAL domain CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 Pfam PF13185 GAF domain 155 300 1.5E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 Gene3D G3DSA:3.30.70.270 318 476 7.5E-54 T 29-03-2018 CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 SUPERFAMILY SSF55785 23 133 9.42E-27 T 29-03-2018 IPR000014 PAS domain CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 SUPERFAMILY SSF55781 126 300 2.4E-16 T 29-03-2018 IPR029016 GAF domain-like CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 Gene3D G3DSA:3.30.450.40 139 317 5.9E-20 T 29-03-2018 IPR029016 GAF domain-like CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 Pfam PF13426 PAS domain 29 131 4.7E-23 T 29-03-2018 IPR000014 PAS domain CB4_RS14295 7e54cd8c2106f080c6cd6f2997057e67 739 Pfam PF00990 Diguanylate cyclase, GGDEF domain 312 465 2.8E-42 T 29-03-2018 IPR000160 GGDEF domain CB4_RS02815 63df2856d02c1bee89fc5fc22e04fe17 422 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 414 2.7E-161 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS02815 63df2856d02c1bee89fc5fc22e04fe17 422 SUPERFAMILY SSF55205 2 415 5.72E-131 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CB4_RS02815 63df2856d02c1bee89fc5fc22e04fe17 422 Gene3D G3DSA:3.65.10.10 217 418 4.6E-47 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS02815 63df2856d02c1bee89fc5fc22e04fe17 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 405 2.9E-89 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS02815 63df2856d02c1bee89fc5fc22e04fe17 422 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 415 41.294 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS02815 63df2856d02c1bee89fc5fc22e04fe17 422 Gene3D G3DSA:3.65.10.10 21 216 5.2E-43 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS14380 c8109c8438baee51044b6570c32bad7b 182 Pfam PF12867 DinB superfamily 9 167 2.8E-11 T 29-03-2018 IPR024775 DinB-like domain CB4_RS14380 c8109c8438baee51044b6570c32bad7b 182 SUPERFAMILY SSF109854 4 65 3.4E-19 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CB4_RS14380 c8109c8438baee51044b6570c32bad7b 182 SUPERFAMILY SSF109854 97 167 3.4E-19 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CB4_RS14380 c8109c8438baee51044b6570c32bad7b 182 Gene3D G3DSA:1.20.120.450 1 179 9.2E-27 T 29-03-2018 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 8.9E-259 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 SUPERFAMILY SSF56712 4 589 2.35E-199 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 SMART SM00436 104 192 3.6E-53 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Gene3D G3DSA:3.40.50.140 2 129 2.1E-39 T 29-03-2018 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Pfam PF01131 DNA topoisomerase 127 547 8.0E-133 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 577 613 5.2E-15 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 617 655 7.1E-15 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 658 675 0.18 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 2.5E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 2.5E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 2.5E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 2.5E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 2.5E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Gene3D G3DSA:2.20.25.10 657 692 0.035 T 29-03-2018 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 633 55.278 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Gene3D G3DSA:1.10.460.10 135 327 5.1E-48 T 29-03-2018 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Gene3D G3DSA:1.10.460.10 446 564 4.9E-25 T 29-03-2018 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 SMART SM00437 242 510 1.7E-116 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Gene3D G3DSA:3.30.65.10 615 656 8.1E-10 T 29-03-2018 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Gene3D G3DSA:3.30.65.10 565 614 5.2E-17 T 29-03-2018 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 SUPERFAMILY SSF57783 573 613 1.21E-13 T 29-03-2018 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Gene3D G3DSA:2.70.20.10 328 445 1.6E-41 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 Pfam PF01751 Toprim domain 5 113 7.0E-28 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS09045 da9b4ce0b84eed52d8bba653cfa5c042 693 SMART SM00493 3 103 4.6E-32 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS07215 de4568a540c4e5a7e019c291018ce62d 433 Pfam PF01523 Putative modulator of DNA gyrase 18 295 7.1E-44 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CB4_RS07215 de4568a540c4e5a7e019c291018ce62d 433 SUPERFAMILY SSF111283 2 432 7.72E-88 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CB4_RS07215 de4568a540c4e5a7e019c291018ce62d 433 Gene3D G3DSA:3.30.2290.10 1 201 4.1E-30 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CB4_RS05085 9bd0d9d67c987840677acdd45785cb92 285 SUPERFAMILY SSF48179 185 285 3.66E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS05085 9bd0d9d67c987840677acdd45785cb92 285 SUPERFAMILY SSF51735 3 185 1.87E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS05085 9bd0d9d67c987840677acdd45785cb92 285 Gene3D G3DSA:3.40.50.720 1 184 1.2E-52 T 29-03-2018 CB4_RS05085 9bd0d9d67c987840677acdd45785cb92 285 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 283 8.5E-31 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS05085 9bd0d9d67c987840677acdd45785cb92 285 PIRSF PIRSF000105 1 285 4.8E-91 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CB4_RS05085 9bd0d9d67c987840677acdd45785cb92 285 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 184 1.9E-62 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS05085 9bd0d9d67c987840677acdd45785cb92 285 Gene3D G3DSA:1.10.1040.10 185 285 5.5E-29 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CB4_RS14210 2d4f8e00e8f839096809dd5752e3be2b 80 SUPERFAMILY SSF50182 6 64 1.08E-24 T 29-03-2018 IPR010920 LSM domain CB4_RS14210 2d4f8e00e8f839096809dd5752e3be2b 80 Pfam PF17209 Hfq protein 7 70 8.4E-34 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CB4_RS14210 2d4f8e00e8f839096809dd5752e3be2b 80 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 9.2E-33 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CB4_RS14210 2d4f8e00e8f839096809dd5752e3be2b 80 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 30.155 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CB4_RS14210 2d4f8e00e8f839096809dd5752e3be2b 80 Gene3D G3DSA:2.30.30.100 4 74 2.5E-33 T 29-03-2018 CB4_RS14965 722286597f0c6272d5664d5a4247aded 289 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 278 1.2E-107 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CB4_RS14965 722286597f0c6272d5664d5a4247aded 289 Gene3D G3DSA:3.30.1300.10 173 288 4.2E-34 T 29-03-2018 CB4_RS14965 722286597f0c6272d5664d5a4247aded 289 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 24 71 2.9E-8 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CB4_RS14965 722286597f0c6272d5664d5a4247aded 289 Hamap MF_00158 Pantothenate synthetase [panC]. 2 277 41.126 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CB4_RS14965 722286597f0c6272d5664d5a4247aded 289 SUPERFAMILY SSF52374 1 279 6.17E-109 T 29-03-2018 CB4_RS14965 722286597f0c6272d5664d5a4247aded 289 Gene3D G3DSA:3.40.50.620 1 172 1.8E-79 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS14965 722286597f0c6272d5664d5a4247aded 289 Pfam PF02569 Pantoate-beta-alanine ligase 3 275 5.5E-106 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CB4_RS04325 5de84db42f9886c26ad4acbb40004ef7 222 SUPERFAMILY SSF54211 2 132 9.1E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS04325 5de84db42f9886c26ad4acbb40004ef7 222 Pfam PF01205 Uncharacterized protein family UPF0029 19 121 7.2E-32 T 29-03-2018 IPR001498 Impact, N-terminal CB4_RS04325 5de84db42f9886c26ad4acbb40004ef7 222 Gene3D G3DSA:3.30.70.240 136 198 4.6E-16 T 29-03-2018 CB4_RS04325 5de84db42f9886c26ad4acbb40004ef7 222 SUPERFAMILY SSF54980 139 200 2.37E-10 T 29-03-2018 IPR035647 EF-G domain III/V-like CB4_RS04325 5de84db42f9886c26ad4acbb40004ef7 222 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 1.2E-15 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CB4_RS04325 5de84db42f9886c26ad4acbb40004ef7 222 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 29-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CB4_RS04325 5de84db42f9886c26ad4acbb40004ef7 222 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 196 1.5E-64 T 29-03-2018 IPR015796 Impact family, bacterial/archaeal CB4_RS04325 5de84db42f9886c26ad4acbb40004ef7 222 Gene3D G3DSA:3.30.230.30 4 133 7.7E-45 T 29-03-2018 IPR001498 Impact, N-terminal CB4_RS08015 7712b2353b5adeffe29f7b5dd2cb5a64 262 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 2 262 2.4E-123 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 CB4_RS08015 7712b2353b5adeffe29f7b5dd2cb5a64 262 SUPERFAMILY SSF52172 2 130 1.29E-33 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS08015 7712b2353b5adeffe29f7b5dd2cb5a64 262 Gene3D G3DSA:1.10.10.10 148 258 2.2E-54 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08015 7712b2353b5adeffe29f7b5dd2cb5a64 262 Gene3D G3DSA:3.40.50.2300 3 137 3.0E-33 T 29-03-2018 CB4_RS08015 7712b2353b5adeffe29f7b5dd2cb5a64 262 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 151 259 7.0E-53 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 CB4_RS08015 7712b2353b5adeffe29f7b5dd2cb5a64 262 Pfam PF00072 Response regulator receiver domain 6 119 1.4E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS08015 7712b2353b5adeffe29f7b5dd2cb5a64 262 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 152 255 1.2E-45 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 CB4_RS08015 7712b2353b5adeffe29f7b5dd2cb5a64 262 SMART SM00448 4 119 6.9E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS08015 7712b2353b5adeffe29f7b5dd2cb5a64 262 PIRSF PIRSF002937 1 262 3.1E-128 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 CB4_RS08015 7712b2353b5adeffe29f7b5dd2cb5a64 262 SUPERFAMILY SSF46894 146 260 1.11E-48 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS20085 24c1ea3e68313a1b21f8642403b6276f 182 Gene3D G3DSA:3.40.1000.10 32 182 1.2E-7 T 29-03-2018 CB4_RS06865 1b195a846c6f4ac515b1fdd7e3bf75b3 379 SUPERFAMILY SSF53098 84 356 5.16E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS06865 1b195a846c6f4ac515b1fdd7e3bf75b3 379 Gene3D G3DSA:3.90.350.10 89 296 7.4E-22 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CB4_RS06865 1b195a846c6f4ac515b1fdd7e3bf75b3 379 Pfam PF01609 Transposase DDE domain 111 320 1.3E-31 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CB4_RS17120 1b195a846c6f4ac515b1fdd7e3bf75b3 379 SUPERFAMILY SSF53098 84 356 5.16E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS17120 1b195a846c6f4ac515b1fdd7e3bf75b3 379 Gene3D G3DSA:3.90.350.10 89 296 7.4E-22 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CB4_RS17120 1b195a846c6f4ac515b1fdd7e3bf75b3 379 Pfam PF01609 Transposase DDE domain 111 320 1.3E-31 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CB4_RS17960 1b195a846c6f4ac515b1fdd7e3bf75b3 379 SUPERFAMILY SSF53098 84 356 5.16E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS17960 1b195a846c6f4ac515b1fdd7e3bf75b3 379 Gene3D G3DSA:3.90.350.10 89 296 7.4E-22 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CB4_RS17960 1b195a846c6f4ac515b1fdd7e3bf75b3 379 Pfam PF01609 Transposase DDE domain 111 320 1.3E-31 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CB4_RS20105 0575bd3cb760afcbeb6eb58b8bd22330 230 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS20105 0575bd3cb760afcbeb6eb58b8bd22330 230 Gene3D G3DSA:3.40.50.1860 118 214 4.3E-27 T 29-03-2018 CB4_RS20105 0575bd3cb760afcbeb6eb58b8bd22330 230 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 223 5.0E-62 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS20105 0575bd3cb760afcbeb6eb58b8bd22330 230 SUPERFAMILY SSF53681 104 214 8.18E-34 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS20105 0575bd3cb760afcbeb6eb58b8bd22330 230 Gene3D G3DSA:3.40.50.1860 1 117 7.1E-33 T 29-03-2018 CB4_RS20105 0575bd3cb760afcbeb6eb58b8bd22330 230 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 230 5.7E-78 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CB4_RS20105 0575bd3cb760afcbeb6eb58b8bd22330 230 SUPERFAMILY SSF53681 1 116 7.85E-38 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS20105 0575bd3cb760afcbeb6eb58b8bd22330 230 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 192 202 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS01445 7b97775c93d1a7f52602ebc34e291493 97 Pfam PF01479 S4 domain 1 47 3.8E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS01445 7b97775c93d1a7f52602ebc34e291493 97 PIRSF PIRSF038881 1 89 1.2E-32 T 29-03-2018 IPR025490 RNA-binding protein, HP1423 type CB4_RS01445 7b97775c93d1a7f52602ebc34e291493 97 Gene3D G3DSA:3.10.290.10 1 94 1.7E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS01445 7b97775c93d1a7f52602ebc34e291493 97 SMART SM00363 1 64 2.4E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS01445 7b97775c93d1a7f52602ebc34e291493 97 SUPERFAMILY SSF55174 1 80 3.66E-22 T 29-03-2018 CB4_RS11340 349f4a39684d9dd142e5564f12becf54 586 SUPERFAMILY SSF52540 399 580 2.18E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11340 349f4a39684d9dd142e5564f12becf54 586 SUPERFAMILY SSF52540 234 273 2.18E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11340 349f4a39684d9dd142e5564f12becf54 586 SMART SM00487 111 297 4.3E-19 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS11340 349f4a39684d9dd142e5564f12becf54 586 Pfam PF00271 Helicase conserved C-terminal domain 411 542 2.7E-10 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS11340 349f4a39684d9dd142e5564f12becf54 586 Gene3D G3DSA:3.40.50.10810 101 363 1.1E-35 T 29-03-2018 CB4_RS11340 349f4a39684d9dd142e5564f12becf54 586 Gene3D G3DSA:3.40.50.300 396 580 4.3E-27 T 29-03-2018 CB4_RS11340 349f4a39684d9dd142e5564f12becf54 586 SMART SM00490 438 542 0.0016 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS11340 349f4a39684d9dd142e5564f12becf54 586 Pfam PF00176 SNF2 family N-terminal domain 133 391 9.1E-31 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CB4_RS11340 349f4a39684d9dd142e5564f12becf54 586 SUPERFAMILY SSF52540 114 331 2.37E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05780 b72a11d3ff2cf37a575b193ad72baa32 333 Gene3D G3DSA:3.30.420.40 5 181 1.0E-16 T 29-03-2018 CB4_RS05780 b72a11d3ff2cf37a575b193ad72baa32 333 SUPERFAMILY SSF53067 72 185 8.42E-8 T 29-03-2018 CB4_RS05780 b72a11d3ff2cf37a575b193ad72baa32 333 Pfam PF11104 Type IV pilus assembly protein PilM; 23 218 7.0E-10 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM CB4_RS05915 f52987d04121258b05f57c0ef44a91ba 335 Pfam PF01636 Phosphotransferase enzyme family 26 260 6.4E-12 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CB4_RS05915 f52987d04121258b05f57c0ef44a91ba 335 SUPERFAMILY SSF56112 24 292 4.08E-33 T 29-03-2018 IPR011009 Protein kinase-like domain CB4_RS05915 f52987d04121258b05f57c0ef44a91ba 335 Gene3D G3DSA:3.90.1200.10 93 322 7.2E-21 T 29-03-2018 CB4_RS05915 f52987d04121258b05f57c0ef44a91ba 335 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 201 213 - T 29-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 CB4_RS05915 f52987d04121258b05f57c0ef44a91ba 335 Gene3D G3DSA:3.30.200.20 1 90 1.5E-4 T 29-03-2018 CB4_RS16085 8abd9b2eb34fcebd399f2b2268db633f 286 SUPERFAMILY SSF110857 141 262 8.5E-19 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CB4_RS16085 8abd9b2eb34fcebd399f2b2268db633f 286 SUPERFAMILY SSF110857 6 133 1.09E-23 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CB4_RS16085 8abd9b2eb34fcebd399f2b2268db633f 286 Gene3D G3DSA:3.10.490.10 140 286 3.5E-29 T 29-03-2018 CB4_RS16085 8abd9b2eb34fcebd399f2b2268db633f 286 Gene3D G3DSA:3.10.490.10 5 139 1.8E-25 T 29-03-2018 CB4_RS16085 8abd9b2eb34fcebd399f2b2268db633f 286 Pfam PF13772 AIG2-like family 200 278 2.6E-17 T 29-03-2018 CB4_RS16085 8abd9b2eb34fcebd399f2b2268db633f 286 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 7 131 6.4E-23 T 29-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CB4_RS06515 3759a8fe8300c50b01edc33d2ab853a6 474 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 151 339 4.0E-7 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CB4_RS06515 3759a8fe8300c50b01edc33d2ab853a6 474 Gene3D G3DSA:3.20.140.10 1 382 1.2E-124 T 29-03-2018 CB4_RS06515 3759a8fe8300c50b01edc33d2ab853a6 474 SUPERFAMILY SSF51690 134 471 4.71E-119 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CB4_RS06515 3759a8fe8300c50b01edc33d2ab853a6 474 PIRSF PIRSF000484 1 474 7.4E-149 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CB4_RS06515 3759a8fe8300c50b01edc33d2ab853a6 474 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 5 461 2.5E-171 T 29-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CB4_RS06515 3759a8fe8300c50b01edc33d2ab853a6 474 SUPERFAMILY SSF54675 3 133 1.43E-46 T 29-03-2018 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 SMART SM00387 485 597 1.4E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 Gene3D G3DSA:3.30.450.20 35 171 3.8E-24 T 29-03-2018 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 Pfam PF00989 PAS fold 257 361 3.1E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 575 1.8E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 581 594 1.8E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 550 1.8E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 536 1.8E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 Pfam PF00512 His Kinase A (phospho-acceptor) domain 372 437 1.2E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 SUPERFAMILY SSF55874 427 595 7.53E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 253 370 3.7E-8 T 29-03-2018 IPR000014 PAS domain CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 Pfam PF00672 HAMP domain 197 246 2.9E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 Gene3D G3DSA:3.30.450.20 253 376 1.0E-18 T 29-03-2018 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 Gene3D G3DSA:3.30.565.10 442 604 7.8E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 SMART SM00304 197 249 2.1E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 SUPERFAMILY SSF158472 197 247 6.15E-10 T 29-03-2018 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 SMART SM00388 371 438 3.6E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 SMART SM00091 256 322 7.4E-6 T 29-03-2018 IPR000014 PAS domain CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 SUPERFAMILY SSF55785 243 363 3.14E-12 T 29-03-2018 IPR000014 PAS domain CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 SUPERFAMILY SSF47384 356 438 8.83E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 Gene3D G3DSA:1.10.287.130 377 434 8.7E-18 T 29-03-2018 CB4_RS02050 dcfbc38edb40168a38261182e8febc8b 604 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 596 2.8E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 Gene3D G3DSA:3.40.50.10420 62 136 2.4E-8 T 29-03-2018 CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 Gene3D G3DSA:3.40.50.10420 137 290 4.5E-49 T 29-03-2018 CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 451 3.9E-176 T 29-03-2018 IPR004452 4Fe-4S binding protein GO:0019516 CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 Pfam PF11870 Domain of unknown function (DUF3390) 394 466 6.5E-14 T 29-03-2018 IPR024569 4Fe-4S binding protein, C-terminal CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 SUPERFAMILY SSF46548 267 397 3.31E-18 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 Pfam PF13183 4Fe-4S dicluster domain 307 374 2.2E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 310 321 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 SUPERFAMILY SSF100950 62 87 3.1E-44 T 29-03-2018 CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 SUPERFAMILY SSF100950 133 293 3.1E-44 T 29-03-2018 CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 Gene3D G3DSA:3.30.70.20 318 364 2.9E-8 T 29-03-2018 CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 Pfam PF02589 LUD domain 68 292 3.1E-57 T 29-03-2018 IPR003741 LUD domain CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 Gene3D G3DSA:3.30.70.20 365 389 0.25 T 29-03-2018 CB4_RS18040 94ed3eb86d83ce4cd09555ab6ef25819 470 Gene3D G3DSA:3.30.70.20 291 317 0.0013 T 29-03-2018 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 522 658 4.5E-47 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 Pfam PF08264 Anticodon-binding domain of tRNA 399 545 6.3E-8 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 SUPERFAMILY SSF52374 2 350 1.21E-113 T 29-03-2018 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 SUPERFAMILY SSF47323 353 572 1.36E-45 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 512 50.272 T 29-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 SUPERFAMILY SSF50249 558 656 6.37E-36 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 259 274 1.4E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 351 362 1.4E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.4E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 226 237 1.4E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 1.4E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.4E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 Gene3D G3DSA:3.40.50.620 2 347 4.1E-99 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 514 1.7E-169 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 Pfam PF09334 tRNA synthetases class I (M) 5 363 7.2E-117 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 Gene3D G3DSA:1.10.730.10 348 513 2.1E-40 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 Pfam PF01588 Putative tRNA binding domain 565 656 2.6E-30 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 Gene3D G3DSA:2.40.50.140 558 659 1.1E-32 T 29-03-2018 CB4_RS01550 5486a0dcac52c988d2b283ba507afa49 659 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 23 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS15485 095a62ca7fb7838daee834c864a86690 197 Pfam PF05521 Phage head-tail joining protein 43 85 1.8E-7 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CB4_RS09575 71f647bb7c3546eb2388c8c9b111c3b7 1649 SUPERFAMILY SSF52540 1204 1522 2.5E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09575 71f647bb7c3546eb2388c8c9b111c3b7 1649 SUPERFAMILY SSF52540 298 364 2.5E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09575 71f647bb7c3546eb2388c8c9b111c3b7 1649 Pfam PF13087 AAA domain 1308 1490 6.2E-16 T 29-03-2018 CB4_RS09575 71f647bb7c3546eb2388c8c9b111c3b7 1649 Pfam PF13195 Protein of unknown function (DUF4011) 22 186 1.6E-30 T 29-03-2018 IPR025103 Protein of unknown function DUF4011 CB4_RS09575 71f647bb7c3546eb2388c8c9b111c3b7 1649 Gene3D G3DSA:3.40.960.10 1536 1647 2.0E-28 T 29-03-2018 CB4_RS09575 71f647bb7c3546eb2388c8c9b111c3b7 1649 Gene3D G3DSA:3.40.50.300 1311 1516 3.8E-19 T 29-03-2018 CB4_RS09575 71f647bb7c3546eb2388c8c9b111c3b7 1649 SMART SM00952 1582 1635 8.4E-5 T 29-03-2018 IPR013584 RAP domain CB4_RS09575 71f647bb7c3546eb2388c8c9b111c3b7 1649 SUPERFAMILY SSF52980 1533 1640 3.59E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CB4_RS09575 71f647bb7c3546eb2388c8c9b111c3b7 1649 Gene3D G3DSA:3.40.50.300 291 1289 2.3E-34 T 29-03-2018 CB4_RS02140 ec92d32c3b68fdb6ea681e2705a44502 373 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 372 8.9E-75 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS02140 ec92d32c3b68fdb6ea681e2705a44502 373 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 201 370 1.5E-26 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 Gene3D G3DSA:1.10.150.80 507 593 6.4E-28 T 29-03-2018 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 SMART SM00956 405 508 5.3E-38 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 SUPERFAMILY SSF52540 58 346 1.48E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 Pfam PF09382 RQC domain 401 512 1.5E-31 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 Gene3D G3DSA:3.40.50.300 205 346 6.0E-32 T 29-03-2018 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 7 586 1.9E-236 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 Pfam PF16124 RecQ zinc-binding 335 397 2.5E-19 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 Pfam PF00270 DEAD/DEAH box helicase 21 182 3.3E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 SMART SM00341 513 593 1.4E-21 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 SUPERFAMILY SSF46785 397 539 2.18E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 Gene3D G3DSA:1.10.10.10 347 506 1.1E-49 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 454 1.3E-141 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 Pfam PF00570 HRDC domain 517 583 1.0E-23 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 SMART SM00490 243 324 2.1E-24 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 Pfam PF00271 Helicase conserved C-terminal domain 218 323 8.6E-18 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 SUPERFAMILY SSF47819 515 587 5.98E-25 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 SMART SM00487 14 211 3.2E-26 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS00775 278f1dbbf5b78dabe1a71d9e915c472c 593 Gene3D G3DSA:3.40.50.300 2 201 1.6E-30 T 29-03-2018 CB4_RS12325 bcfd7388a790c0dad4ce3318bb4ab2e7 282 Gene3D G3DSA:3.20.80.10 129 272 1.8E-23 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CB4_RS12325 bcfd7388a790c0dad4ce3318bb4ab2e7 282 SMART SM00871 122 271 4.6E-9 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CB4_RS12325 bcfd7388a790c0dad4ce3318bb4ab2e7 282 Pfam PF06445 GyrI-like small molecule binding domain 124 271 1.6E-12 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CB4_RS12325 bcfd7388a790c0dad4ce3318bb4ab2e7 282 Gene3D G3DSA:1.10.1660.10 1 61 8.4E-20 T 29-03-2018 CB4_RS12325 bcfd7388a790c0dad4ce3318bb4ab2e7 282 SUPERFAMILY SSF46955 5 109 5.49E-28 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS12325 bcfd7388a790c0dad4ce3318bb4ab2e7 282 SUPERFAMILY SSF55136 122 270 8.2E-32 T 29-03-2018 CB4_RS12325 bcfd7388a790c0dad4ce3318bb4ab2e7 282 Gene3D G3DSA:1.10.1660.10 62 128 3.7E-11 T 29-03-2018 CB4_RS12325 bcfd7388a790c0dad4ce3318bb4ab2e7 282 Pfam PF13411 MerR HTH family regulatory protein 5 73 4.2E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS12325 bcfd7388a790c0dad4ce3318bb4ab2e7 282 SMART SM00422 5 75 5.6E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS03215 5e0be25374e7d146691eaa6acc4d6944 262 Gene3D G3DSA:3.40.50.150 11 243 2.6E-15 T 29-03-2018 CB4_RS03215 5e0be25374e7d146691eaa6acc4d6944 262 SUPERFAMILY SSF53335 49 181 4.85E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS03215 5e0be25374e7d146691eaa6acc4d6944 262 SUPERFAMILY SSF53335 210 241 4.85E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS03215 5e0be25374e7d146691eaa6acc4d6944 262 Pfam PF13847 Methyltransferase domain 74 170 4.1E-11 T 29-03-2018 IPR025714 Methyltransferase domain CB4_RS04755 055da0e947ea82154c4c8b320c424521 305 SUPERFAMILY SSF103481 41 141 2.22E-12 T 29-03-2018 CB4_RS04755 055da0e947ea82154c4c8b320c424521 305 SUPERFAMILY SSF103481 189 286 1.83E-12 T 29-03-2018 CB4_RS04755 055da0e947ea82154c4c8b320c424521 305 Pfam PF00892 EamA-like transporter family 150 286 2.1E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS04755 055da0e947ea82154c4c8b320c424521 305 Pfam PF00892 EamA-like transporter family 7 139 1.1E-23 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS16250 122cedb510adba26817803a81d749839 333 Gene3D G3DSA:3.40.50.300 1 332 1.2E-77 T 29-03-2018 CB4_RS16250 122cedb510adba26817803a81d749839 333 SUPERFAMILY SSF52540 3 253 4.42E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS16250 122cedb510adba26817803a81d749839 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 2.2E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CB4_RS16250 122cedb510adba26817803a81d749839 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 319 1.1E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CB4_RS16250 122cedb510adba26817803a81d749839 333 SMART SM00382 32 240 7.0E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS16250 122cedb510adba26817803a81d749839 333 Pfam PF00005 ABC transporter 24 182 1.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS16250 122cedb510adba26817803a81d749839 333 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS04760 82a702d53317806862b238435b9518d0 139 PIRSF PIRSF033736 1 139 1.1E-45 T 29-03-2018 IPR017021 Uncharacterised conserved protein UCP033763 CB4_RS04760 82a702d53317806862b238435b9518d0 139 Pfam PF09391 Protein of unknown function (DUF2000) 6 139 8.1E-46 T 29-03-2018 IPR018988 Protein of unknown function DUF2000 CB4_RS04760 82a702d53317806862b238435b9518d0 139 Gene3D G3DSA:3.40.1490.10 6 137 1.6E-44 T 29-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CB4_RS04760 82a702d53317806862b238435b9518d0 139 SUPERFAMILY SSF102462 4 139 7.32E-40 T 29-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CB4_RS10630 95ba975a4d00eac6065da803fddb4a93 100 Gene3D G3DSA:2.60.300.12 1 97 2.4E-15 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CB4_RS10630 95ba975a4d00eac6065da803fddb4a93 100 SUPERFAMILY SSF89360 3 93 1.53E-12 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CB4_RS08895 45ac84713ee4b8bb73f39d8279cd1631 593 Pfam PF03354 Phage Terminase 111 568 1.0E-78 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CB4_RS03100 3e053d468c297669a34d055f4ed982f9 287 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 147 2.4E-26 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CB4_RS03100 3e053d468c297669a34d055f4ed982f9 287 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 229 283 1.2E-12 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CB4_RS03100 3e053d468c297669a34d055f4ed982f9 287 Pfam PF00460 Flagella basal body rod protein 7 35 2.9E-9 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CB4_RS03100 3e053d468c297669a34d055f4ed982f9 287 SUPERFAMILY SSF117143 93 210 1.2E-11 T 29-03-2018 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 8.4E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 8.4E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 SMART SM00354 2 72 1.4E-39 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 SUPERFAMILY SSF47413 3 60 7.6E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 TIGRFAM TIGR01481 ccpA: catabolite control protein A 3 332 4.5E-150 T 29-03-2018 IPR006377 Catabolite control protein A GO:0006355 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 Pfam PF13377 Periplasmic binding protein-like domain 170 331 5.9E-38 T 29-03-2018 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 29-03-2018 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.7E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 Gene3D G3DSA:3.40.50.2300 59 167 5.0E-31 T 29-03-2018 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 Gene3D G3DSA:3.40.50.2300 168 334 5.7E-51 T 29-03-2018 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 Gene3D G3DSA:1.10.260.40 3 58 1.3E-26 T 29-03-2018 CB4_RS17325 7b4ccf64abe2833e568b062a1060ec38 342 SUPERFAMILY SSF53822 62 333 1.27E-90 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS09665 256469447ce4a22e7bba3e42ba209506 113 Gene3D G3DSA:3.30.457.10 1 29 3.0E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS09665 256469447ce4a22e7bba3e42ba209506 113 Gene3D G3DSA:3.30.457.10 30 88 1.2E-29 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS09665 256469447ce4a22e7bba3e42ba209506 113 Gene3D G3DSA:3.30.457.10 89 113 3.2E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS09665 256469447ce4a22e7bba3e42ba209506 113 SUPERFAMILY SSF55383 20 104 2.42E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS09665 256469447ce4a22e7bba3e42ba209506 113 Pfam PF07833 Copper amine oxidase N-terminal domain 2 33 1.9E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS09665 256469447ce4a22e7bba3e42ba209506 113 Pfam PF07833 Copper amine oxidase N-terminal domain 18 109 6.5E-35 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS11240 9e5c0c1761ef1956634a02e761b8d54d 354 Gene3D G3DSA:3.50.50.60 1 60 9.8E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS11240 9e5c0c1761ef1956634a02e761b8d54d 354 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 63 3.4E-13 T 29-03-2018 CB4_RS11240 9e5c0c1761ef1956634a02e761b8d54d 354 Gene3D G3DSA:3.90.660.10 61 299 7.1E-35 T 29-03-2018 CB4_RS11240 9e5c0c1761ef1956634a02e761b8d54d 354 SUPERFAMILY SSF51905 300 349 7.59E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS11240 9e5c0c1761ef1956634a02e761b8d54d 354 SUPERFAMILY SSF51905 1 212 7.59E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS11240 9e5c0c1761ef1956634a02e761b8d54d 354 Pfam PF01593 Flavin containing amine oxidoreductase 95 347 3.5E-10 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CB4_RS18110 5758aeba5fa13d77d97266739be3136f 259 SUPERFAMILY SSF52096 1 258 8.76E-89 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS18110 5758aeba5fa13d77d97266739be3136f 259 Gene3D G3DSA:1.10.12.10 220 257 1.3E-14 T 29-03-2018 IPR014748 Crontonase, C-terminal CB4_RS18110 5758aeba5fa13d77d97266739be3136f 259 Gene3D G3DSA:3.90.226.10 1 219 1.2E-71 T 29-03-2018 CB4_RS18110 5758aeba5fa13d77d97266739be3136f 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 258 3.6E-68 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CB4_RS18110 5758aeba5fa13d77d97266739be3136f 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CB4_RS05860 303e0acc15f999d26ec279421cbb82b4 112 SUPERFAMILY SSF118010 1 107 7.06E-28 T 29-03-2018 IPR007422 Cysteine protease Prp CB4_RS05860 303e0acc15f999d26ec279421cbb82b4 112 Gene3D G3DSA:3.30.70.1490 2 110 1.2E-30 T 29-03-2018 IPR007422 Cysteine protease Prp CB4_RS05860 303e0acc15f999d26ec279421cbb82b4 112 Pfam PF04327 Cysteine protease Prp 1 104 6.3E-25 T 29-03-2018 IPR007422 Cysteine protease Prp CB4_RS11915 c929bbeba07333912a5666a4c1dfe61e 69 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 16 63 1.5E-19 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CB4_RS11915 c929bbeba07333912a5666a4c1dfe61e 69 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 24 33 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS11915 c929bbeba07333912a5666a4c1dfe61e 69 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 42 56 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 34 388 1.4E-18 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 Gene3D G3DSA:2.40.37.10 283 436 2.5E-45 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 Gene3D G3DSA:3.20.20.10 38 282 2.5E-63 T 29-03-2018 IPR029066 PLP-binding barrel CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 SUPERFAMILY SSF51419 30 299 2.33E-81 T 29-03-2018 IPR029066 PLP-binding barrel CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 2.0E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 2.0E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 2.0E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 2.0E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 SUPERFAMILY SSF50621 274 431 3.35E-56 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 237 250 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 430 4.0E-158 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 41 297 2.5E-67 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 1.7E-16 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 1.7E-16 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 1.7E-16 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 81 1.7E-16 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 1.7E-16 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CB4_RS16165 01f0467f2193f2c1a791c81d71bd99c6 439 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 41.385 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS14740 e6e07c5f2f9eb7d4c5da31cae4bbaed0 120 Pfam PF00072 Response regulator receiver domain 5 116 1.4E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS14740 e6e07c5f2f9eb7d4c5da31cae4bbaed0 120 SMART SM00448 3 115 5.5E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS14740 e6e07c5f2f9eb7d4c5da31cae4bbaed0 120 SUPERFAMILY SSF52172 3 120 3.42E-40 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS14740 e6e07c5f2f9eb7d4c5da31cae4bbaed0 120 Gene3D G3DSA:3.40.50.2300 1 120 1.7E-41 T 29-03-2018 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 Gene3D G3DSA:3.30.450.20 183 304 1.2E-27 T 29-03-2018 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 Gene3D G3DSA:1.10.287.950 323 423 5.4E-9 T 29-03-2018 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 SUPERFAMILY SSF58104 412 681 1.57E-73 T 29-03-2018 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 SUPERFAMILY SSF58104 345 379 1.57E-73 T 29-03-2018 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 Gene3D G3DSA:3.30.450.20 62 182 1.1E-19 T 29-03-2018 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 SUPERFAMILY SSF103190 119 206 8.37E-6 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 SMART SM00283 406 681 1.6E-80 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 Gene3D G3DSA:1.10.287.950 624 682 2.9E-8 T 29-03-2018 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 Gene3D G3DSA:1.10.287.950 431 623 1.9E-53 T 29-03-2018 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 Pfam PF02743 Cache domain 38 287 2.8E-30 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 SMART SM00304 325 377 6.2E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 453 632 4.8E-45 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS19395 20601cc654f810c287b00bd6b14572b1 682 Pfam PF00672 HAMP domain 325 373 2.8E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14325 a83d5c530a721d78c7767b7fe28d50b2 189 Gene3D G3DSA:1.10.10.60 1 46 1.9E-14 T 29-03-2018 CB4_RS14325 a83d5c530a721d78c7767b7fe28d50b2 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 46 4.6E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS14325 a83d5c530a721d78c7767b7fe28d50b2 189 Gene3D G3DSA:1.10.357.10 47 186 1.1E-18 T 29-03-2018 CB4_RS14325 a83d5c530a721d78c7767b7fe28d50b2 189 SUPERFAMILY SSF46689 2 65 5.64E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS14325 a83d5c530a721d78c7767b7fe28d50b2 189 SUPERFAMILY SSF48498 69 184 2.1E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS18545 eb9149589d5dd20f520f0a04a03f0831 633 Gene3D G3DSA:3.30.70.270 190 363 1.1E-59 T 29-03-2018 CB4_RS18545 eb9149589d5dd20f520f0a04a03f0831 633 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 198 360 7.7E-41 T 29-03-2018 IPR000160 GGDEF domain CB4_RS18545 eb9149589d5dd20f520f0a04a03f0831 633 SMART SM00052 372 619 5.8E-122 T 29-03-2018 IPR001633 EAL domain CB4_RS18545 eb9149589d5dd20f520f0a04a03f0831 633 SMART SM00267 191 362 2.7E-62 T 29-03-2018 IPR000160 GGDEF domain CB4_RS18545 eb9149589d5dd20f520f0a04a03f0831 633 Pfam PF00563 EAL domain 378 614 4.9E-72 T 29-03-2018 IPR001633 EAL domain CB4_RS18545 eb9149589d5dd20f520f0a04a03f0831 633 Gene3D G3DSA:3.20.20.450 364 633 3.1E-105 T 29-03-2018 IPR001633 EAL domain CB4_RS18545 eb9149589d5dd20f520f0a04a03f0831 633 SUPERFAMILY SSF55073 207 364 2.59E-50 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS18545 eb9149589d5dd20f520f0a04a03f0831 633 Pfam PF00990 Diguanylate cyclase, GGDEF domain 202 358 2.0E-47 T 29-03-2018 IPR000160 GGDEF domain CB4_RS18545 eb9149589d5dd20f520f0a04a03f0831 633 SUPERFAMILY SSF141868 377 627 4.97E-91 T 29-03-2018 IPR001633 EAL domain CB4_RS11090 52801cfceea1b518da3a85af0316754e 402 Gene3D G3DSA:3.30.70.260 325 399 7.5E-7 T 29-03-2018 CB4_RS11090 52801cfceea1b518da3a85af0316754e 402 Gene3D G3DSA:3.40.50.1100 132 324 1.5E-49 T 29-03-2018 CB4_RS11090 52801cfceea1b518da3a85af0316754e 402 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 398 8.2E-155 T 29-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CB4_RS11090 52801cfceea1b518da3a85af0316754e 402 SUPERFAMILY SSF55021 325 393 2.52E-6 T 29-03-2018 CB4_RS11090 52801cfceea1b518da3a85af0316754e 402 SUPERFAMILY SSF53686 4 314 1.96E-101 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS11090 52801cfceea1b518da3a85af0316754e 402 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 303 1.8E-86 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS11090 52801cfceea1b518da3a85af0316754e 402 Gene3D G3DSA:3.40.50.1100 29 131 2.6E-33 T 29-03-2018 CB4_RS16910 67f4a9bfeab31fdf57e9ed01b7dd189d 710 SUPERFAMILY SSF56349 392 574 1.74E-11 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS16910 67f4a9bfeab31fdf57e9ed01b7dd189d 710 Pfam PF00589 Phage integrase family 393 566 1.1E-7 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS16910 67f4a9bfeab31fdf57e9ed01b7dd189d 710 Gene3D G3DSA:1.10.443.10 383 584 3.2E-15 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS13365 67f4a9bfeab31fdf57e9ed01b7dd189d 710 SUPERFAMILY SSF56349 392 574 1.74E-11 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS13365 67f4a9bfeab31fdf57e9ed01b7dd189d 710 Pfam PF00589 Phage integrase family 393 566 1.1E-7 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS13365 67f4a9bfeab31fdf57e9ed01b7dd189d 710 Gene3D G3DSA:1.10.443.10 383 584 3.2E-15 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS10900 f5fbe528d08dcae0c1e7708b646d76ae 411 Gene3D G3DSA:1.20.1250.20 222 411 1.7E-20 T 29-03-2018 CB4_RS10900 f5fbe528d08dcae0c1e7708b646d76ae 411 SUPERFAMILY SSF103473 24 407 5.1E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS10900 f5fbe528d08dcae0c1e7708b646d76ae 411 ProSitePatterns PS00216 Sugar transport proteins signature 1. 291 307 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CB4_RS10900 f5fbe528d08dcae0c1e7708b646d76ae 411 Gene3D G3DSA:1.20.1250.20 26 220 6.8E-18 T 29-03-2018 CB4_RS10900 f5fbe528d08dcae0c1e7708b646d76ae 411 Pfam PF07690 Major Facilitator Superfamily 40 375 6.5E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS19500 461a9ed78ad29dfa7ecec2e6a42f1c3e 288 Pfam PF11959 Domain of unknown function (DUF3473) 143 271 3.1E-35 T 29-03-2018 IPR022560 Domain of unknown function DUF3473 CB4_RS19500 461a9ed78ad29dfa7ecec2e6a42f1c3e 288 Gene3D G3DSA:3.20.20.370 1 275 9.1E-39 T 29-03-2018 CB4_RS19500 461a9ed78ad29dfa7ecec2e6a42f1c3e 288 Pfam PF01522 Polysaccharide deacetylase 27 132 3.1E-20 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS19500 461a9ed78ad29dfa7ecec2e6a42f1c3e 288 SUPERFAMILY SSF88713 7 244 4.45E-40 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 Gene3D G3DSA:1.25.40.20 20 123 1.2E-22 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 PRINTS PR01415 Ankyrin repeat signature 151 165 7.8E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 PRINTS PR01415 Ankyrin repeat signature 70 85 7.8E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 SMART SM00248 36 65 520.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 SMART SM00248 168 197 0.0049 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 SMART SM00248 200 231 2500.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 SMART SM00248 135 164 3.1E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 SMART SM00248 69 98 0.097 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 SMART SM00248 102 132 1.7 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 SUPERFAMILY SSF48403 38 225 2.26E-42 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 Pfam PF12796 Ankyrin repeats (3 copies) 107 197 8.1E-16 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 Pfam PF12796 Ankyrin repeats (3 copies) 36 100 2.5E-8 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 Gene3D G3DSA:1.25.40.20 124 180 1.6E-19 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 SUPERFAMILY SSF49785 262 348 1.06E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 Gene3D G3DSA:1.25.40.20 181 242 5.1E-8 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CB4_RS06360 d8f0ecea521a09ce6eeaa38205e5cbbf 362 Pfam PF08305 NPCBM/NEW2 domain 264 353 2.7E-7 T 29-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 1.1E-44 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 Gene3D G3DSA:3.30.1490.20 124 209 5.9E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 SUPERFAMILY SSF56059 83 348 2.12E-73 T 29-03-2018 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 SMART SM00878 336 442 9.4E-70 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 SUPERFAMILY SSF51246 331 442 8.89E-47 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 5.4E-48 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 Gene3D G3DSA:3.30.470.20 210 444 2.4E-108 T 29-03-2018 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 3.1E-236 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 SUPERFAMILY SSF52440 1 113 1.87E-51 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 Gene3D G3DSA:3.40.50.20 1 123 6.5E-55 T 29-03-2018 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS07935 2fbc9ec3823811f4d1ce358b5100e5ac 451 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 1.8E-85 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 Gene3D G3DSA:3.30.70.870 386 462 3.4E-14 T 29-03-2018 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 525 49.032 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 SUPERFAMILY SSF52540 4 272 3.86E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 SUPERFAMILY SSF54980 389 461 2.41E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 146 1.5E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 Pfam PF00009 Elongation factor Tu GTP binding domain 9 272 7.8E-52 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 Gene3D G3DSA:2.40.30.10 271 385 8.1E-21 T 29-03-2018 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 SUPERFAMILY SSF50447 256 381 5.3E-26 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 Pfam PF16658 Class II release factor RF3, C-terminal domain 383 512 6.4E-45 T 29-03-2018 IPR032090 Peptide chain release factor 3, C-terminal CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 6 524 6.3E-203 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CB4_RS17390 10e26e41e168b3869322b8acc3e0422f 527 Gene3D G3DSA:3.40.50.300 2 270 9.0E-38 T 29-03-2018 CB4_RS10150 ab0d7ad94a7f5d241fcde4da373f5800 337 SMART SM00382 28 209 7.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS10150 ab0d7ad94a7f5d241fcde4da373f5800 337 Pfam PF08402 TOBE domain 257 337 5.9E-6 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CB4_RS10150 ab0d7ad94a7f5d241fcde4da373f5800 337 Gene3D G3DSA:3.40.50.300 1 236 4.2E-75 T 29-03-2018 CB4_RS10150 ab0d7ad94a7f5d241fcde4da373f5800 337 Pfam PF00005 ABC transporter 19 159 1.3E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS10150 ab0d7ad94a7f5d241fcde4da373f5800 337 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS10150 ab0d7ad94a7f5d241fcde4da373f5800 337 SUPERFAMILY SSF50331 225 335 4.7E-5 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CB4_RS10150 ab0d7ad94a7f5d241fcde4da373f5800 337 SUPERFAMILY SSF52540 4 242 3.28E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12460 8374577099ad20bbe91cd741d87d0a76 148 Pfam PF13027 Protein of unknown function (DUF3888) 44 127 3.0E-14 T 29-03-2018 IPR024984 Protein of unknown function DUF3888 CB4_RS08630 0f32153e08da7a3fcb0f268ce9480b0e 413 SUPERFAMILY SSF53901 214 410 7.57E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS08630 0f32153e08da7a3fcb0f268ce9480b0e 413 PIRSF PIRSF000447 1 413 1.4E-192 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CB4_RS08630 0f32153e08da7a3fcb0f268ce9480b0e 413 Gene3D G3DSA:3.40.47.10 5 259 8.0E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS08630 0f32153e08da7a3fcb0f268ce9480b0e 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CB4_RS08630 0f32153e08da7a3fcb0f268ce9480b0e 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 246 2.2E-61 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CB4_RS08630 0f32153e08da7a3fcb0f268ce9480b0e 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 409 9.9E-206 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CB4_RS08630 0f32153e08da7a3fcb0f268ce9480b0e 413 SUPERFAMILY SSF53901 3 251 1.98E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS08630 0f32153e08da7a3fcb0f268ce9480b0e 413 SMART SM00825 Beta-ketoacyl synthase 5 413 8.7E-15 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CB4_RS08630 0f32153e08da7a3fcb0f268ce9480b0e 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 1.1E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CB4_RS08630 0f32153e08da7a3fcb0f268ce9480b0e 413 Gene3D G3DSA:3.40.47.10 260 411 1.4E-53 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS12350 c21e7eee4af0875baccd651ea6e644de 355 Gene3D G3DSA:3.20.10.10 175 338 3.6E-54 T 29-03-2018 CB4_RS12350 c21e7eee4af0875baccd651ea6e644de 355 SUPERFAMILY SSF56752 7 352 3.01E-118 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CB4_RS12350 c21e7eee4af0875baccd651ea6e644de 355 Gene3D G3DSA:3.30.470.10 1 174 1.8E-69 T 29-03-2018 CB4_RS12350 c21e7eee4af0875baccd651ea6e644de 355 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 43 355 3.5E-127 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CB4_RS12350 c21e7eee4af0875baccd651ea6e644de 355 PIRSF PIRSF006468 1 355 1.2E-135 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CB4_RS12350 c21e7eee4af0875baccd651ea6e644de 355 ProSitePatterns PS00770 Aminotransferases class-IV signature. 232 261 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CB4_RS12350 c21e7eee4af0875baccd651ea6e644de 355 Pfam PF01063 Amino-transferase class IV 68 311 7.1E-37 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CB4_RS17615 386254e1ceb0f5d2ec39d14a2fcbe75b 228 SMART SM00895 80 206 7.9E-10 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS17615 386254e1ceb0f5d2ec39d14a2fcbe75b 228 Pfam PF07729 FCD domain 83 202 5.1E-19 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS17615 386254e1ceb0f5d2ec39d14a2fcbe75b 228 SUPERFAMILY SSF48008 76 209 5.75E-18 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS17615 386254e1ceb0f5d2ec39d14a2fcbe75b 228 SUPERFAMILY SSF46785 4 74 2.01E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS17615 386254e1ceb0f5d2ec39d14a2fcbe75b 228 Gene3D G3DSA:1.20.120.530 73 224 2.5E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS17615 386254e1ceb0f5d2ec39d14a2fcbe75b 228 SMART SM00345 12 70 1.7E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS17615 386254e1ceb0f5d2ec39d14a2fcbe75b 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 3.7E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS17615 386254e1ceb0f5d2ec39d14a2fcbe75b 228 Gene3D G3DSA:1.10.10.10 1 72 7.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 Gene3D G3DSA:3.40.50.1380 1 193 1.1E-71 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 PIRSF PIRSF000414 1 513 1.5E-214 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 Gene3D G3DSA:3.40.140.20 362 503 1.3E-51 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 513 44.77 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 Pfam PF02142 MGS-like domain 15 130 2.1E-28 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 SMART SM00798 135 448 3.5E-199 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 447 1.5E-120 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 SUPERFAMILY SSF52335 3 195 5.49E-68 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 513 7.3E-225 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 Gene3D G3DSA:3.40.140.20 226 360 3.7E-54 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 SMART SM00851 15 130 1.2E-52 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS20350 d5e11b1692a28cf9cedd02de7f064dab 513 SUPERFAMILY SSF53927 208 513 1.91E-127 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CB4_RS06765 51c9c462dfb81485cb5dbc1842d80356 194 SUPERFAMILY SSF49879 95 192 4.78E-15 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CB4_RS06765 51c9c462dfb81485cb5dbc1842d80356 194 Gene3D G3DSA:2.60.200.20 73 194 9.4E-17 T 29-03-2018 CB4_RS06765 51c9c462dfb81485cb5dbc1842d80356 194 Pfam PF00498 FHA domain 110 186 3.7E-10 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 Gene3D G3DSA:3.40.50.1980 19 217 3.8E-93 T 29-03-2018 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 PRINTS PR00083 Histidinol dehydrogenase signature 221 242 1.6E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 PRINTS PR00083 Histidinol dehydrogenase signature 312 337 1.6E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 PRINTS PR00083 Histidinol dehydrogenase signature 162 188 1.6E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 PRINTS PR00083 Histidinol dehydrogenase signature 127 153 1.6E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 PRINTS PR00083 Histidinol dehydrogenase signature 243 262 1.6E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 PRINTS PR00083 Histidinol dehydrogenase signature 192 217 1.6E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 PRINTS PR00083 Histidinol dehydrogenase signature 26 50 1.6E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 PRINTS PR00083 Histidinol dehydrogenase signature 353 371 1.6E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 Pfam PF00815 Histidinol dehydrogenase 20 419 3.7E-179 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 SUPERFAMILY SSF53720 19 421 1.71E-90 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 Gene3D G3DSA:3.40.50.1980 218 363 5.5E-69 T 29-03-2018 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 26 418 2.3E-175 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 PIRSF PIRSF000099 4 422 1.2E-178 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 221 253 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS03675 f5842fbe6e900d29e2f2d69454284a3d 424 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 4 419 44.085 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 SUPERFAMILY SSF55874 402 571 4.45E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 Gene3D G3DSA:1.10.287.130 352 395 8.9E-18 T 29-03-2018 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 SUPERFAMILY SSF47384 330 414 2.94E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 460 568 1.1E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 Gene3D G3DSA:3.30.450.20 228 351 1.8E-14 T 29-03-2018 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 SMART SM00388 346 413 1.1E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 SMART SM00091 231 298 0.0011 T 29-03-2018 IPR000014 PAS domain CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 PRINTS PR00344 Bacterial sensor protein C-terminal signature 555 568 5.4E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 524 5.4E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 549 5.4E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 510 5.4E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 SUPERFAMILY SSF158472 173 222 4.05E-12 T 29-03-2018 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 Gene3D G3DSA:3.30.450.20 2 145 0.012 T 29-03-2018 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 SMART SM00387 459 571 1.3E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 Pfam PF00512 His Kinase A (phospho-acceptor) domain 347 413 2.9E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 Pfam PF00672 HAMP domain 173 220 7.5E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 Gene3D G3DSA:3.30.565.10 396 571 7.4E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 SUPERFAMILY SSF55785 224 338 1.67E-8 T 29-03-2018 IPR000014 PAS domain CB4_RS15940 8b4c88e0af8bc043b964aea0793c399a 577 SMART SM00304 172 224 4.2E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 SUPERFAMILY SSF58104 233 528 2.62E-74 T 29-03-2018 CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 8.5E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 429 8.5E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 371 398 8.5E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 SMART SM00304 213 265 1.6E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 182 1.6E-37 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 Gene3D G3DSA:1.20.120.30 26 184 2.2E-17 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 495 1.3E-44 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 Pfam PF00672 HAMP domain 213 257 2.7E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 Gene3D G3DSA:1.10.287.950 308 528 8.1E-55 T 29-03-2018 CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 Gene3D G3DSA:1.10.287.500 233 307 0.051 T 29-03-2018 CB4_RS16270 e07f76aa6cf0295fb63ab731846ac877 528 SMART SM00283 280 527 6.3E-79 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 SUPERFAMILY SSF53901 5 276 1.77E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 397 2.8E-147 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 ProSitePatterns PS00737 Thiolases signature 2. 345 361 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 Gene3D G3DSA:3.40.47.10 276 396 8.1E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 Pfam PF02803 Thiolase, C-terminal domain 276 398 2.6E-50 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 Gene3D G3DSA:3.40.47.10 1 275 2.4E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 SUPERFAMILY SSF53901 277 398 3.06E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 Pfam PF00108 Thiolase, N-terminal domain 5 268 1.4E-85 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CB4_RS05100 43f7cc7e2951a6489e830ff0a342abe7 399 PIRSF PIRSF000429 1 399 6.7E-137 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS11700 67112d20756acd2dda6eac51dea63536 84 Pfam PF11417 Loader and inhibitor of phage G40P 1 62 2.2E-9 T 29-03-2018 IPR024424 Replicative helicase inhibitor G39P, N-terminal CB4_RS11700 67112d20756acd2dda6eac51dea63536 84 Gene3D G3DSA:1.10.8.200 4 63 2.3E-18 T 29-03-2018 CB4_RS14245 668b2c8dd971a21c8dc8149693c6870a 138 Pfam PF06146 Phosphate-starvation-inducible E 59 123 2.3E-16 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like CB4_RS14245 668b2c8dd971a21c8dc8149693c6870a 138 PIRSF PIRSF029598 4 138 1.3E-38 T 29-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 CB4_RS05110 061e87323dee1c5d24751800cb18c894 336 Gene3D G3DSA:1.10.3470.10 15 305 1.0E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS05110 061e87323dee1c5d24751800cb18c894 336 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 300 4.6E-38 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS12545 09ee169d1d064bc7eab57bcf7aa61626 218 Pfam PF12804 MobA-like NTP transferase domain 24 184 6.8E-33 T 29-03-2018 IPR025877 MobA-like NTP transferase CB4_RS12545 09ee169d1d064bc7eab57bcf7aa61626 218 SUPERFAMILY SSF53448 21 210 1.96E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS12545 09ee169d1d064bc7eab57bcf7aa61626 218 Gene3D G3DSA:3.90.550.10 9 214 1.3E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS12545 09ee169d1d064bc7eab57bcf7aa61626 218 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 20 212 24.404 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CB4_RS00955 fe7e0912cb22d106fdd5a00f86d839e4 210 SUPERFAMILY SSF50447 1 207 6.71E-79 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CB4_RS00955 fe7e0912cb22d106fdd5a00f86d839e4 210 Pfam PF00297 Ribosomal protein L3 99 181 1.8E-14 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00955 fe7e0912cb22d106fdd5a00f86d839e4 210 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 2.0E-85 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00955 fe7e0912cb22d106fdd5a00f86d839e4 210 Gene3D G3DSA:4.10.960.10 58 164 2.8E-32 T 29-03-2018 CB4_RS00955 fe7e0912cb22d106fdd5a00f86d839e4 210 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site CB4_RS00955 fe7e0912cb22d106fdd5a00f86d839e4 210 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 38.388 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 Gene3D G3DSA:3.30.450.40 175 342 1.3E-27 T 29-03-2018 IPR029016 GAF domain-like CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 Pfam PF00990 Diguanylate cyclase, GGDEF domain 346 498 1.7E-45 T 29-03-2018 IPR000160 GGDEF domain CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 Gene3D G3DSA:3.30.450.40 3 174 2.9E-17 T 29-03-2018 IPR029016 GAF domain-like CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 SMART SM00065 191 343 5.8E-15 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 SMART SM00065 15 173 0.0055 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 Pfam PF13185 GAF domain 194 333 2.7E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 Gene3D G3DSA:3.30.70.270 343 503 2.6E-56 T 29-03-2018 CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 SMART SM00267 335 502 5.8E-63 T 29-03-2018 IPR000160 GGDEF domain CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 343 501 1.4E-51 T 29-03-2018 IPR000160 GGDEF domain CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 SUPERFAMILY SSF55781 12 171 3.49E-12 T 29-03-2018 IPR029016 GAF domain-like CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 SUPERFAMILY SSF55781 197 346 6.54E-24 T 29-03-2018 IPR029016 GAF domain-like CB4_RS08145 1cf057cd389c2613c0595307f5fbda09 503 SUPERFAMILY SSF55073 351 501 1.49E-48 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 SUPERFAMILY SSF53223 87 236 1.37E-56 T 29-03-2018 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 SMART SM00919 238 460 5.5E-109 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 Gene3D G3DSA:3.40.50.10380 89 235 8.3E-40 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 PIRSF PIRSF000106 26 478 2.1E-92 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 ProSitePatterns PS00331 Malic enzymes signature. 234 250 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 Pfam PF03949 Malic enzyme, NAD binding domain 240 444 1.6E-22 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 Gene3D G3DSA:3.30.70.260 6 88 5.8E-4 T 29-03-2018 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 Gene3D G3DSA:3.40.50.720 236 478 1.6E-76 T 29-03-2018 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 PRINTS PR00072 Malic enzyme signature 234 250 2.6E-7 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 PRINTS PR00072 Malic enzyme signature 265 281 2.6E-7 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 PRINTS PR00072 Malic enzyme signature 155 177 2.6E-7 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 SMART SM01274 93 226 1.4E-83 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 SUPERFAMILY SSF51735 238 474 2.54E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS03960 3ba0db0d97be300afe7970d2745f6823 478 Pfam PF00390 Malic enzyme, N-terminal domain 94 226 3.5E-30 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CB4_RS05985 c18ce3eca498011f756ab63d0a00ec7d 76 Pfam PF13797 Post-transcriptional regulator 7 74 1.9E-19 T 29-03-2018 IPR025716 Post-transcriptional regulator CB4_RS05840 0b65ae5ff689fd7380e32ca29de240ba 328 Gene3D G3DSA:2.70.70.10 32 327 6.3E-19 T 29-03-2018 CB4_RS05840 0b65ae5ff689fd7380e32ca29de240ba 328 Pfam PF01551 Peptidase family M23 234 321 9.2E-17 T 29-03-2018 IPR016047 Peptidase M23 CB4_RS05840 0b65ae5ff689fd7380e32ca29de240ba 328 SUPERFAMILY SSF51261 203 322 6.8E-17 T 29-03-2018 IPR011055 Duplicated hybrid motif CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Pfam PF07993 Male sterility protein 877 1119 1.3E-54 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 SUPERFAMILY SSF47336 763 834 7.59E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 268 682 3.8E-123 T 29-03-2018 IPR010071 Amino acid adenylation domain CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Gene3D G3DSA:1.10.1200.10 775 849 4.0E-17 T 29-03-2018 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Gene3D G3DSA:3.40.50.980 398 569 1.6E-38 T 29-03-2018 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 SUPERFAMILY SSF51735 873 1157 4.52E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 PIRSF PIRSF001617 702 1185 2.7E-54 T 29-03-2018 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 PIRSF PIRSF001617 8 357 1.7E-21 T 29-03-2018 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 PIRSF PIRSF001617 385 710 7.5E-20 T 29-03-2018 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Pfam PF00550 Phosphopantetheine attachment site 773 833 3.7E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Gene3D G3DSA:3.40.50.980 238 397 6.7E-47 T 29-03-2018 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 874 1237 2.1E-67 T 29-03-2018 IPR010080 Thioester reductase-like domain CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Pfam PF00668 Condensation domain 174 223 3.2E-5 T 29-03-2018 IPR001242 Condensation domain CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Pfam PF00668 Condensation domain 6 136 1.5E-11 T 29-03-2018 IPR001242 Condensation domain CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 ProSitePatterns PS00455 Putative AMP-binding domain signature. 393 404 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Gene3D G3DSA:3.30.300.30 653 774 6.1E-33 T 29-03-2018 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 SUPERFAMILY SSF52777 8 211 1.89E-19 T 29-03-2018 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Pfam PF13193 AMP-binding enzyme C-terminal domain 666 741 1.8E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Pfam PF00501 AMP-binding enzyme 249 658 2.2E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 SUPERFAMILY SSF56801 208 782 3.66E-147 T 29-03-2018 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Gene3D G3DSA:2.30.38.10 570 648 1.7E-22 T 29-03-2018 CB4_RS14410 819a21d4bf033a3b660b336f36423cc9 1248 Gene3D G3DSA:3.40.50.720 869 1215 2.0E-40 T 29-03-2018 CB4_RS17770 a8d2128bb8bc043ce107e949dc07cd4b 142 Gene3D G3DSA:3.30.1130.10 6 141 2.1E-28 T 29-03-2018 CB4_RS17770 a8d2128bb8bc043ce107e949dc07cd4b 142 PIRSF PIRSF027377 4 141 6.3E-45 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CB4_RS17770 a8d2128bb8bc043ce107e949dc07cd4b 142 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 142 38.544 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CB4_RS17770 a8d2128bb8bc043ce107e949dc07cd4b 142 SUPERFAMILY SSF55620 21 131 9.64E-24 T 29-03-2018 CB4_RS17770 a8d2128bb8bc043ce107e949dc07cd4b 142 Pfam PF14489 QueF-like protein 60 138 2.1E-29 T 29-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CB4_RS17770 a8d2128bb8bc043ce107e949dc07cd4b 142 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 27 137 2.3E-40 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 475 9.0E-168 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 Pfam PF00571 CBS domain 151 206 1.1E-9 T 29-03-2018 IPR000644 CBS domain CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 Pfam PF00571 CBS domain 97 142 2.7E-10 T 29-03-2018 IPR000644 CBS domain CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 SUPERFAMILY SSF54631 65 206 5.65E-32 T 29-03-2018 CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 9.1E-201 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 296 308 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 Gene3D G3DSA:3.20.20.70 3 485 1.6E-118 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 SMART SM00116 159 207 6.5E-10 T 29-03-2018 IPR000644 CBS domain CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 SMART SM00116 98 146 1.1E-9 T 29-03-2018 IPR000644 CBS domain CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 SUPERFAMILY SSF51412 218 479 2.49E-129 T 29-03-2018 CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 SUPERFAMILY SSF51412 6 92 2.49E-129 T 29-03-2018 CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 PIRSF PIRSF000130 1 489 1.5E-215 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 SMART SM01240 9 475 0.0 T 29-03-2018 CB4_RS01855 6bd4b7763a7e04dbca327ca4943c160a 489 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 488 86.29 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Gene3D G3DSA:3.30.450.20 467 609 2.3E-29 T 29-03-2018 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SUPERFAMILY SSF55785 222 349 9.42E-20 T 29-03-2018 IPR000014 PAS domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Pfam PF08448 PAS fold 369 473 5.5E-9 T 29-03-2018 IPR013656 PAS fold-4 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 719 823 1.4E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 481 604 1.9E-18 T 29-03-2018 IPR000014 PAS domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 233 358 3.6E-17 T 29-03-2018 IPR000014 PAS domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SUPERFAMILY SSF55874 667 824 7.33E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 PRINTS PR00344 Bacterial sensor protein C-terminal signature 774 784 3.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 PRINTS PR00344 Bacterial sensor protein C-terminal signature 809 822 3.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 PRINTS PR00344 Bacterial sensor protein C-terminal signature 756 770 3.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 PRINTS PR00344 Bacterial sensor protein C-terminal signature 785 803 3.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Pfam PF10114 Sensory domain found in PocR 20 180 3.2E-46 T 29-03-2018 IPR018771 PocR domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Gene3D G3DSA:3.30.450.40 105 227 7.2E-4 T 29-03-2018 IPR029016 GAF domain-like CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SUPERFAMILY SSF55785 347 446 1.21E-14 T 29-03-2018 IPR000014 PAS domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SUPERFAMILY SSF55785 468 594 2.9E-23 T 29-03-2018 IPR000014 PAS domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Pfam PF08447 PAS fold 506 591 2.9E-11 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Gene3D G3DSA:3.30.450.20 355 466 1.5E-16 T 29-03-2018 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Gene3D G3DSA:1.10.287.130 610 672 8.2E-14 T 29-03-2018 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Pfam PF00512 His Kinase A (phospho-acceptor) domain 614 674 3.0E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Pfam PF00989 PAS fold 237 324 5.1E-11 T 29-03-2018 IPR013767 PAS fold GO:0006355 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SMART SM00388 613 676 1.6E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SMART SM00086 556 598 0.0026 T 29-03-2018 IPR001610 PAC motif CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Gene3D G3DSA:3.30.565.10 676 832 4.6E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SUPERFAMILY SSF47384 606 674 9.42E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SMART SM00091 237 306 1.0E-7 T 29-03-2018 IPR000014 PAS domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SMART SM00091 483 550 3.7E-8 T 29-03-2018 IPR000014 PAS domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SMART SM00091 363 429 0.95 T 29-03-2018 IPR000014 PAS domain CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 Gene3D G3DSA:3.30.450.20 228 354 3.4E-22 T 29-03-2018 CB4_RS12695 bc2d1e2fa2966c4790b1715dfb23fbb4 833 SMART SM00387 718 825 3.7E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS08240 f999dce240cd555841807fa7f148ccca 320 Pfam PF00953 Glycosyl transferase family 4 78 244 3.5E-38 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CB4_RS08240 f999dce240cd555841807fa7f148ccca 320 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 1.1E-5 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CB4_RS08240 f999dce240cd555841807fa7f148ccca 320 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CB4_RS08240 f999dce240cd555841807fa7f148ccca 320 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 318 24.022 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CB4_RS08240 f999dce240cd555841807fa7f148ccca 320 ProSitePatterns PS01348 MraY family signature 2. 164 175 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CB4_RS08240 f999dce240cd555841807fa7f148ccca 320 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 18 314 1.1E-115 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CB4_RS16630 360308aa95bceb63f6c83dfad14e7291 135 Gene3D G3DSA:1.10.490.10 1 130 2.8E-33 T 29-03-2018 CB4_RS16630 360308aa95bceb63f6c83dfad14e7291 135 SUPERFAMILY SSF46458 5 122 2.26E-38 T 29-03-2018 IPR009050 Globin-like CB4_RS16630 360308aa95bceb63f6c83dfad14e7291 135 Pfam PF01152 Bacterial-like globin 7 121 3.5E-32 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CB4_RS07690 0cbb0aa5046fdd622d76960623946c68 60 Gene3D G3DSA:2.10.260.10 1 44 1.6E-5 T 29-03-2018 CB4_RS07690 0cbb0aa5046fdd622d76960623946c68 60 SUPERFAMILY SSF89447 5 48 6.28E-7 T 29-03-2018 CB4_RS06125 d5409d0e02f5ed35f65ec5a160e198ec 215 Pfam PF01596 O-methyltransferase 22 210 1.2E-34 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CB4_RS06125 d5409d0e02f5ed35f65ec5a160e198ec 215 Gene3D G3DSA:3.40.50.150 4 212 3.2E-45 T 29-03-2018 CB4_RS06125 d5409d0e02f5ed35f65ec5a160e198ec 215 SUPERFAMILY SSF53335 2 212 3.04E-49 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 SUPERFAMILY SSF52540 574 844 1.23E-115 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 SUPERFAMILY SSF52540 5 179 1.23E-115 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 SUPERFAMILY SSF52540 342 540 1.23E-115 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 SUPERFAMILY SSF52540 884 910 1.23E-115 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 Gene3D G3DSA:3.40.50.300 1 476 6.3E-56 T 29-03-2018 CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 SUPERFAMILY SSF52980 1041 1262 3.75E-31 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1085 1260 9.9E-11 T 29-03-2018 CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 10 1260 0.0 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 464 4.4E-82 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 Pfam PF13361 UvrD-like helicase C-terminal domain 474 907 1.5E-29 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 Gene3D G3DSA:3.90.320.10 1031 1262 6.1E-42 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 Gene3D G3DSA:1.10.486.10 643 796 5.5E-38 T 29-03-2018 CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 8 1262 19.178 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CB4_RS13830 e08ed0c26283df0e1c24470926f81597 1263 Gene3D G3DSA:3.40.50.300 477 642 4.2E-20 T 29-03-2018 CB4_RS03295 72513f5ed985f8a95ac7e5d1619c8820 179 Gene3D G3DSA:1.10.1740.10 1 91 2.4E-9 T 29-03-2018 CB4_RS03295 72513f5ed985f8a95ac7e5d1619c8820 179 Pfam PF04542 Sigma-70 region 2 10 75 2.1E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS03295 72513f5ed985f8a95ac7e5d1619c8820 179 SUPERFAMILY SSF88659 105 174 1.68E-8 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS03295 72513f5ed985f8a95ac7e5d1619c8820 179 SUPERFAMILY SSF88946 6 84 5.65E-10 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS03295 72513f5ed985f8a95ac7e5d1619c8820 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 166 4.4E-12 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS03295 72513f5ed985f8a95ac7e5d1619c8820 179 Gene3D G3DSA:1.10.10.10 94 177 9.2E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15945 b18cd836ddfc71ed0fd01eeff9d8208b 237 Gene3D G3DSA:3.40.50.2300 1 126 2.0E-39 T 29-03-2018 CB4_RS15945 b18cd836ddfc71ed0fd01eeff9d8208b 237 SUPERFAMILY SSF46894 131 235 4.68E-32 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS15945 b18cd836ddfc71ed0fd01eeff9d8208b 237 SUPERFAMILY SSF52172 3 125 2.28E-43 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS15945 b18cd836ddfc71ed0fd01eeff9d8208b 237 SMART SM00448 5 115 2.2E-47 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS15945 b18cd836ddfc71ed0fd01eeff9d8208b 237 Pfam PF00072 Response regulator receiver domain 7 115 2.6E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS15945 b18cd836ddfc71ed0fd01eeff9d8208b 237 Gene3D G3DSA:1.10.10.10 127 237 2.7E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15945 b18cd836ddfc71ed0fd01eeff9d8208b 237 SMART SM00862 156 233 1.8E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS15945 b18cd836ddfc71ed0fd01eeff9d8208b 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 233 1.2E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS03890 edf8c09b99828d87bb9f3604c4b1ce84 239 SUPERFAMILY SSF53474 5 229 3.99E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS03890 edf8c09b99828d87bb9f3604c4b1ce84 239 Gene3D G3DSA:3.40.50.1820 4 231 1.2E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS03890 edf8c09b99828d87bb9f3604c4b1ce84 239 Pfam PF12146 Serine aminopeptidase, S33 4 213 2.8E-18 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CB4_RS03890 edf8c09b99828d87bb9f3604c4b1ce84 239 PIRSF PIRSF017388 1 231 1.9E-62 T 29-03-2018 IPR012354 Esterase/lipase GO:0052689 CB4_RS03495 6acd3404b5fe15de55932ad7309bd839 225 SUPERFAMILY SSF161098 14 207 6.8E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS03495 6acd3404b5fe15de55932ad7309bd839 225 Gene3D G3DSA:1.10.3720.10 2 225 2.0E-47 T 29-03-2018 CB4_RS03495 6acd3404b5fe15de55932ad7309bd839 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 222 9.5E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS03495 6acd3404b5fe15de55932ad7309bd839 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 116 1.6E-19 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 Gene3D G3DSA:1.20.1640.10 815 1033 5.9E-41 T 29-03-2018 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 Pfam PF00873 AcrB/AcrD/AcrF family 4 1017 7.8E-188 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 Gene3D G3DSA:3.30.2090.10 183 264 2.0E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 Gene3D G3DSA:3.30.2090.10 701 801 6.5E-6 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 Gene3D G3DSA:3.30.70.1430 41 141 1.6E-12 T 29-03-2018 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 SUPERFAMILY SSF82693 548 653 2.35E-6 T 29-03-2018 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 Gene3D G3DSA:3.30.70.1430 547 694 2.9E-13 T 29-03-2018 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 SUPERFAMILY SSF82714 185 263 9.02E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 Gene3D G3DSA:1.20.1640.10 265 490 3.3E-39 T 29-03-2018 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 SUPERFAMILY SSF82693 267 322 4.19E-17 T 29-03-2018 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 SUPERFAMILY SSF82693 135 181 4.19E-17 T 29-03-2018 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 SUPERFAMILY SSF82693 41 131 1.23E-10 T 29-03-2018 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 5.3E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 5.3E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 5.3E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 5.3E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 5.3E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 5.3E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 5.3E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 SUPERFAMILY SSF82866 801 1022 1.24E-45 T 29-03-2018 CB4_RS12615 2b17c9467ab4075145794a3a4326be82 1040 SUPERFAMILY SSF82866 290 488 2.35E-37 T 29-03-2018 CB4_RS03245 2a134ab2415cd9039b7ebe4931b3bbb2 166 Gene3D G3DSA:1.25.40.10 95 165 9.1E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS03245 2a134ab2415cd9039b7ebe4931b3bbb2 166 SUPERFAMILY SSF48452 46 162 9.87E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS03245 2a134ab2415cd9039b7ebe4931b3bbb2 166 Gene3D G3DSA:1.25.40.10 16 94 9.2E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS03245 2a134ab2415cd9039b7ebe4931b3bbb2 166 Pfam PF13432 Tetratricopeptide repeat 52 108 2.8E-8 T 29-03-2018 CB4_RS13575 9911328c871a18a48ebf1477429d385f 428 Pfam PF09335 SNARE associated Golgi protein 29 155 2.9E-20 T 29-03-2018 IPR032816 SNARE associated Golgi protein CB4_RS13575 9911328c871a18a48ebf1477429d385f 428 Gene3D G3DSA:1.20.144.10 248 425 2.0E-6 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS13575 9911328c871a18a48ebf1477429d385f 428 Pfam PF01569 PAP2 superfamily 337 412 5.7E-8 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS13575 9911328c871a18a48ebf1477429d385f 428 SUPERFAMILY SSF48317 153 413 8.5E-5 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS15020 74c24b89abebdefb10ec16cc954bf068 285 Pfam PF08281 Sigma-70, region 4 104 154 1.6E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15020 74c24b89abebdefb10ec16cc954bf068 285 Gene3D G3DSA:1.10.1740.10 1 68 1.0E-14 T 29-03-2018 CB4_RS15020 74c24b89abebdefb10ec16cc954bf068 285 Gene3D G3DSA:1.10.10.10 69 152 2.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15020 74c24b89abebdefb10ec16cc954bf068 285 SUPERFAMILY SSF88946 2 87 4.71E-16 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15020 74c24b89abebdefb10ec16cc954bf068 285 Pfam PF04542 Sigma-70 region 2 4 69 1.6E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15020 74c24b89abebdefb10ec16cc954bf068 285 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 3 285 2.2E-97 T 29-03-2018 IPR014303 RNA polymerase sigma-70, ECF type CB4_RS15020 74c24b89abebdefb10ec16cc954bf068 285 SUPERFAMILY SSF54427 169 284 1.59E-12 T 29-03-2018 IPR032710 NTF2-like domain CB4_RS15020 74c24b89abebdefb10ec16cc954bf068 285 Gene3D G3DSA:3.10.450.50 153 285 1.1E-11 T 29-03-2018 CB4_RS15020 74c24b89abebdefb10ec16cc954bf068 285 SUPERFAMILY SSF88659 78 155 4.91E-8 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15020 74c24b89abebdefb10ec16cc954bf068 285 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 154 3.1E-15 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 Gene3D G3DSA:1.10.860.10 469 565 3.0E-9 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 TIGRFAM TIGR01391 dnaG: DNA primase 4 419 3.0E-147 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 PIRSF PIRSF002811 2 606 6.8E-176 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 Pfam PF10410 DnaB-helicase binding domain of primase 370 423 5.8E-12 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 Pfam PF01807 CHC2 zinc finger 6 101 7.9E-38 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 Gene3D G3DSA:1.20.50.20 369 421 1.1E-4 T 29-03-2018 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 SMART SM00493 261 332 3.5E-11 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 3.9E-41 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 Gene3D G3DSA:3.40.1360.10 243 365 2.9E-35 T 29-03-2018 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 Gene3D G3DSA:3.90.580.10 1 102 2.3E-36 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 Hamap MF_00974 DNA primase [dnaG]. 4 596 28.649 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 SMART SM00400 36 90 2.0E-28 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 SUPERFAMILY SSF48024 465 566 2.88E-8 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 Gene3D G3DSA:3.90.980.10 109 242 8.6E-44 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 SUPERFAMILY SSF56731 116 424 7.59E-99 T 29-03-2018 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 SUPERFAMILY SSF57783 4 100 1.34E-35 T 29-03-2018 CB4_RS07150 55e1870a0cf3dae2272f792d20019b19 606 Pfam PF13155 Toprim-like 264 349 6.4E-21 T 29-03-2018 CB4_RS19885 d8928f8cf4eafdf8619369d4a2a75391 324 Gene3D G3DSA:3.20.20.100 3 311 1.2E-98 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CB4_RS19885 d8928f8cf4eafdf8619369d4a2a75391 324 PRINTS PR00069 Aldo-keto reductase signature 103 121 9.0E-10 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS19885 d8928f8cf4eafdf8619369d4a2a75391 324 PRINTS PR00069 Aldo-keto reductase signature 148 165 9.0E-10 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS19885 d8928f8cf4eafdf8619369d4a2a75391 324 PRINTS PR00069 Aldo-keto reductase signature 242 266 9.0E-10 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS19885 d8928f8cf4eafdf8619369d4a2a75391 324 PRINTS PR00069 Aldo-keto reductase signature 39 63 9.0E-10 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CB4_RS19885 d8928f8cf4eafdf8619369d4a2a75391 324 SUPERFAMILY SSF51430 1 314 6.94E-102 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CB4_RS19885 d8928f8cf4eafdf8619369d4a2a75391 324 Pfam PF00248 Aldo/keto reductase family 16 309 7.5E-81 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CB4_RS09105 f47d7eabd36af3e7b6d8983a145a2fe6 434 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 21 433 1.4E-203 T 29-03-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS09105 f47d7eabd36af3e7b6d8983a145a2fe6 434 Gene3D G3DSA:3.40.50.300 90 361 1.1E-84 T 29-03-2018 CB4_RS09105 f47d7eabd36af3e7b6d8983a145a2fe6 434 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 23 88 5.3E-7 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS09105 f47d7eabd36af3e7b6d8983a145a2fe6 434 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 354 8.1E-77 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS09105 f47d7eabd36af3e7b6d8983a145a2fe6 434 SUPERFAMILY SSF52540 92 359 7.43E-97 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09105 f47d7eabd36af3e7b6d8983a145a2fe6 434 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 4 432 4.4E-190 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS09105 f47d7eabd36af3e7b6d8983a145a2fe6 434 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS09105 f47d7eabd36af3e7b6d8983a145a2fe6 434 SMART SM00382 157 338 9.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13300 8ca9424740d7db4a1ff269a60f7ba27f 621 ProSitePatterns PS01074 Terpene synthases signature. 474 488 - T 29-03-2018 IPR002365 Terpene synthase, conserved site GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CB4_RS13300 8ca9424740d7db4a1ff269a60f7ba27f 621 SUPERFAMILY SSF48239 296 615 7.53E-88 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CB4_RS13300 8ca9424740d7db4a1ff269a60f7ba27f 621 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 13 288 1.3E-75 T 29-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CB4_RS13300 8ca9424740d7db4a1ff269a60f7ba27f 621 Gene3D G3DSA:1.50.10.20 287 621 3.8E-90 T 29-03-2018 CB4_RS13300 8ca9424740d7db4a1ff269a60f7ba27f 621 Gene3D G3DSA:1.50.10.20 29 286 6.7E-52 T 29-03-2018 CB4_RS13300 8ca9424740d7db4a1ff269a60f7ba27f 621 SUPERFAMILY SSF48239 31 285 1.54E-47 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CB4_RS13300 8ca9424740d7db4a1ff269a60f7ba27f 621 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 10 618 2.2E-139 T 29-03-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 CB4_RS13300 8ca9424740d7db4a1ff269a60f7ba27f 621 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 300 616 4.9E-96 T 29-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CB4_RS13300 8ca9424740d7db4a1ff269a60f7ba27f 621 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 14 616 4.3E-127 T 29-03-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CB4_RS02255 5ce775c01210a6c9cc97a66e383601f0 301 SUPERFAMILY SSF53850 88 294 2.11E-43 T 29-03-2018 CB4_RS02255 5ce775c01210a6c9cc97a66e383601f0 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.6E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS02255 5ce775c01210a6c9cc97a66e383601f0 301 Gene3D G3DSA:3.40.190.10 181 267 2.8E-24 T 29-03-2018 CB4_RS02255 5ce775c01210a6c9cc97a66e383601f0 301 Pfam PF03466 LysR substrate binding domain 88 292 8.1E-50 T 29-03-2018 IPR005119 LysR, substrate-binding CB4_RS02255 5ce775c01210a6c9cc97a66e383601f0 301 Gene3D G3DSA:3.40.190.10 90 180 1.9E-23 T 29-03-2018 CB4_RS02255 5ce775c01210a6c9cc97a66e383601f0 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS02255 5ce775c01210a6c9cc97a66e383601f0 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS02255 5ce775c01210a6c9cc97a66e383601f0 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS02255 5ce775c01210a6c9cc97a66e383601f0 301 SUPERFAMILY SSF46785 2 84 2.73E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02255 5ce775c01210a6c9cc97a66e383601f0 301 Gene3D G3DSA:1.10.10.10 1 83 1.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14820 f4d9f496812e50e429eaec106ef6a52a 457 SUPERFAMILY SSF102114 160 385 1.05E-55 T 29-03-2018 CB4_RS14820 f4d9f496812e50e429eaec106ef6a52a 457 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 19 456 64.181 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CB4_RS14820 f4d9f496812e50e429eaec106ef6a52a 457 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 166 186 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CB4_RS14820 f4d9f496812e50e429eaec106ef6a52a 457 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 20 454 1.4E-137 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CB4_RS14820 f4d9f496812e50e429eaec106ef6a52a 457 Gene3D G3DSA:2.40.50.140 395 457 3.4E-18 T 29-03-2018 CB4_RS14820 f4d9f496812e50e429eaec106ef6a52a 457 Gene3D G3DSA:3.80.30.20 160 394 9.7E-49 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CB4_RS14820 f4d9f496812e50e429eaec106ef6a52a 457 SMART SM00729 162 380 4.6E-54 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS14820 f4d9f496812e50e429eaec106ef6a52a 457 Pfam PF04055 Radical SAM superfamily 168 335 1.5E-24 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS14820 f4d9f496812e50e429eaec106ef6a52a 457 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 20 454 6.2E-156 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CB4_RS14820 f4d9f496812e50e429eaec106ef6a52a 457 Pfam PF00919 Uncharacterized protein family UPF0004 20 119 7.1E-29 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CB4_RS01460 ca65ab4926fe315ce2ada958711806d3 180 Gene3D G3DSA:3.30.450.40 36 180 1.8E-5 T 29-03-2018 IPR029016 GAF domain-like CB4_RS01460 ca65ab4926fe315ce2ada958711806d3 180 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS01460 ca65ab4926fe315ce2ada958711806d3 180 SUPERFAMILY SSF89447 1 51 1.12E-14 T 29-03-2018 CB4_RS01460 ca65ab4926fe315ce2ada958711806d3 180 PIRSF PIRSF026579 1 180 7.7E-93 T 29-03-2018 IPR014213 Sporulation stage V, protein T CB4_RS01460 ca65ab4926fe315ce2ada958711806d3 180 Gene3D G3DSA:2.10.260.10 1 35 2.5E-20 T 29-03-2018 CB4_RS01460 ca65ab4926fe315ce2ada958711806d3 180 SUPERFAMILY SSF55781 75 179 1.45E-5 T 29-03-2018 IPR029016 GAF domain-like CB4_RS01460 ca65ab4926fe315ce2ada958711806d3 180 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 179 2.6E-49 T 29-03-2018 CB4_RS01460 ca65ab4926fe315ce2ada958711806d3 180 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.3E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS01460 ca65ab4926fe315ce2ada958711806d3 180 SMART SM00966 8 52 1.1E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS01460 ca65ab4926fe315ce2ada958711806d3 180 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 179 9.6E-89 T 29-03-2018 IPR014213 Sporulation stage V, protein T CB4_RS01850 a2fd5e738912a2b54b3f17dbd4b76905 442 SUPERFAMILY SSF56601 18 309 1.82E-75 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS01850 a2fd5e738912a2b54b3f17dbd4b76905 442 Gene3D G3DSA:3.40.710.10 31 308 7.2E-48 T 29-03-2018 CB4_RS01850 a2fd5e738912a2b54b3f17dbd4b76905 442 SUPERFAMILY SSF69189 301 382 7.65E-15 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CB4_RS01850 a2fd5e738912a2b54b3f17dbd4b76905 442 SMART SM00936 309 412 2.6E-11 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CB4_RS01850 a2fd5e738912a2b54b3f17dbd4b76905 442 Gene3D G3DSA:2.60.410.10 309 412 5.8E-14 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CB4_RS01850 a2fd5e738912a2b54b3f17dbd4b76905 442 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 155 168 1.0E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS01850 a2fd5e738912a2b54b3f17dbd4b76905 442 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 72 83 1.0E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS01850 a2fd5e738912a2b54b3f17dbd4b76905 442 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 128 145 1.0E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS01850 a2fd5e738912a2b54b3f17dbd4b76905 442 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 36 289 1.4E-74 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CB4_RS01850 a2fd5e738912a2b54b3f17dbd4b76905 442 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 309 411 1.2E-14 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CB4_RS08350 e88a13de8cbedc3fb56751210907ddaa 257 SMART SM00363 181 238 2.3E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS08350 e88a13de8cbedc3fb56751210907ddaa 257 Gene3D G3DSA:3.10.290.10 178 232 8.0E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS08350 e88a13de8cbedc3fb56751210907ddaa 257 Pfam PF01479 S4 domain 194 227 7.5E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS08350 e88a13de8cbedc3fb56751210907ddaa 257 SUPERFAMILY SSF55174 35 126 9.55E-29 T 29-03-2018 CB4_RS08350 e88a13de8cbedc3fb56751210907ddaa 257 SUPERFAMILY SSF55174 178 251 9.55E-29 T 29-03-2018 CB4_RS14370 1487d77f1ff724e336a0ed54dedd5c97 530 SMART SM00304 171 225 1.9E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14370 1487d77f1ff724e336a0ed54dedd5c97 530 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 268 297 7.1E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS14370 1487d77f1ff724e336a0ed54dedd5c97 530 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 381 410 7.1E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS14370 1487d77f1ff724e336a0ed54dedd5c97 530 SUPERFAMILY SSF58104 260 529 9.29E-82 T 29-03-2018 CB4_RS14370 1487d77f1ff724e336a0ed54dedd5c97 530 SUPERFAMILY SSF58104 193 227 9.29E-82 T 29-03-2018 CB4_RS14370 1487d77f1ff724e336a0ed54dedd5c97 530 Gene3D G3DSA:1.10.287.950 286 530 5.0E-57 T 29-03-2018 CB4_RS14370 1487d77f1ff724e336a0ed54dedd5c97 530 SMART SM00283 254 529 4.9E-88 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14370 1487d77f1ff724e336a0ed54dedd5c97 530 Gene3D G3DSA:1.10.287.950 175 285 3.8E-9 T 29-03-2018 CB4_RS14370 1487d77f1ff724e336a0ed54dedd5c97 530 Pfam PF00672 HAMP domain 174 221 3.9E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14370 1487d77f1ff724e336a0ed54dedd5c97 530 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 298 482 3.4E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS13125 a4d5720bf4948613a8468740ad32acb9 546 Gene3D G3DSA:3.90.76.10 68 166 5.7E-26 T 29-03-2018 CB4_RS13125 a4d5720bf4948613a8468740ad32acb9 546 Gene3D G3DSA:3.40.190.10 167 306 2.5E-35 T 29-03-2018 CB4_RS13125 a4d5720bf4948613a8468740ad32acb9 546 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 96 118 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CB4_RS13125 a4d5720bf4948613a8468740ad32acb9 546 Gene3D G3DSA:3.10.105.10 307 516 2.7E-45 T 29-03-2018 CB4_RS13125 a4d5720bf4948613a8468740ad32acb9 546 TIGRFAM TIGR02294 nickel_nikA: nickel ABC transporter, nickel/metallophore periplasmic binding protein 46 542 5.0E-207 T 29-03-2018 IPR011980 Nickel ABC transporter, substrate-binding protein NikA GO:0015675|GO:0016151|GO:0020037 CB4_RS13125 a4d5720bf4948613a8468740ad32acb9 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 459 1.0E-86 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CB4_RS13125 a4d5720bf4948613a8468740ad32acb9 546 PIRSF PIRSF002741 4 542 1.2E-94 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CB4_RS13125 a4d5720bf4948613a8468740ad32acb9 546 SUPERFAMILY SSF53850 45 534 6.33E-118 T 29-03-2018 CB4_RS14710 1d1438ec09b7946b5090d2af59d3fc62 577 SUPERFAMILY SSF103190 52 176 2.2E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS14710 1d1438ec09b7946b5090d2af59d3fc62 577 SUPERFAMILY SSF58104 306 574 5.75E-62 T 29-03-2018 CB4_RS14710 1d1438ec09b7946b5090d2af59d3fc62 577 SUPERFAMILY SSF58104 243 273 5.75E-62 T 29-03-2018 CB4_RS14710 1d1438ec09b7946b5090d2af59d3fc62 577 Gene3D G3DSA:1.10.287.950 329 577 5.1E-50 T 29-03-2018 CB4_RS14710 1d1438ec09b7946b5090d2af59d3fc62 577 Pfam PF00672 HAMP domain 213 262 1.3E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14710 1d1438ec09b7946b5090d2af59d3fc62 577 Gene3D G3DSA:3.30.450.20 27 185 8.6E-14 T 29-03-2018 CB4_RS14710 1d1438ec09b7946b5090d2af59d3fc62 577 Gene3D G3DSA:1.10.287.950 220 328 3.5E-4 T 29-03-2018 CB4_RS14710 1d1438ec09b7946b5090d2af59d3fc62 577 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 346 527 3.6E-39 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14710 1d1438ec09b7946b5090d2af59d3fc62 577 SMART SM00283 286 575 1.4E-57 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14710 1d1438ec09b7946b5090d2af59d3fc62 577 SMART SM00304 213 271 6.4E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS17685 dc20ec5036e5724b2f07f9cc14a0fec0 558 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 557 47.832 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CB4_RS17685 dc20ec5036e5724b2f07f9cc14a0fec0 558 Gene3D G3DSA:3.40.50.2300 37 267 1.6E-6 T 29-03-2018 CB4_RS17685 dc20ec5036e5724b2f07f9cc14a0fec0 558 SUPERFAMILY SSF52016 377 556 1.41E-61 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CB4_RS17685 dc20ec5036e5724b2f07f9cc14a0fec0 558 Pfam PF00920 Dehydratase family 34 553 2.8E-230 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CB4_RS17685 dc20ec5036e5724b2f07f9cc14a0fec0 558 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CB4_RS17685 dc20ec5036e5724b2f07f9cc14a0fec0 558 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CB4_RS17685 dc20ec5036e5724b2f07f9cc14a0fec0 558 SUPERFAMILY SSF143975 4 376 2.09E-142 T 29-03-2018 CB4_RS17685 dc20ec5036e5724b2f07f9cc14a0fec0 558 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 17 557 6.4E-264 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 Gene3D G3DSA:3.30.230.10 1 79 1.1E-6 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 Gene3D G3DSA:3.30.230.10 80 204 6.5E-23 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 Pfam PF00288 GHMP kinases N terminal domain 101 168 1.6E-14 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 SUPERFAMILY SSF54211 2 187 7.59E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 Gene3D G3DSA:3.30.70.890 205 338 1.1E-21 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 PRINTS PR00960 LmbP protein signature 257 281 2.9E-43 T 29-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 PRINTS PR00960 LmbP protein signature 106 127 2.9E-43 T 29-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 PRINTS PR00960 LmbP protein signature 148 167 2.9E-43 T 29-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 PRINTS PR00960 LmbP protein signature 285 304 2.9E-43 T 29-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 PRINTS PR00960 LmbP protein signature 7 22 2.9E-43 T 29-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 SUPERFAMILY SSF55060 194 339 3.2E-29 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 PIRSF PIRSF036406 1 341 4.0E-149 T 29-03-2018 IPR014606 D,D-heptose 7-phosphate kinase KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CB4_RS03160 6b60b1beeaf13b0ce1905b2617acddac 341 Pfam PF08544 GHMP kinases C terminal 242 321 2.3E-11 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 2.2E-26 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 Gene3D G3DSA:2.40.110.10 120 210 4.9E-38 T 29-03-2018 CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 PIRSF PIRSF016578 2 93 4.5E-7 T 29-03-2018 CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 PIRSF PIRSF016578 134 367 1.7E-16 T 29-03-2018 CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 Gene3D G3DSA:1.10.540.10 1 119 1.6E-32 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 223 377 2.3E-51 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 SUPERFAMILY SSF47203 221 377 2.42E-60 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 211 1.3E-26 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 SUPERFAMILY SSF56645 2 234 1.44E-78 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS01720 68a51e5d81cb0c35424fa99a250f573b 378 Gene3D G3DSA:1.20.140.10 211 378 3.2E-64 T 29-03-2018 CB4_RS02940 61c78a90ff6419b80e333b0a00a4b283 51 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 1 42 1.3E-12 T 29-03-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter CB4_RS05040 4ab1e141fdb793ccdfaa03a5f65a6f30 263 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 10 237 1.6E-41 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CB4_RS05040 4ab1e141fdb793ccdfaa03a5f65a6f30 263 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 187 228 1.3E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS05040 4ab1e141fdb793ccdfaa03a5f65a6f30 263 PIRSF PIRSF000915 3 262 2.9E-59 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CB4_RS05040 4ab1e141fdb793ccdfaa03a5f65a6f30 263 Gene3D G3DSA:3.40.50.1000 1 262 6.2E-36 T 29-03-2018 IPR023214 HAD-like domain CB4_RS05040 4ab1e141fdb793ccdfaa03a5f65a6f30 263 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 114 2.6E-25 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CB4_RS05040 4ab1e141fdb793ccdfaa03a5f65a6f30 263 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 6 261 6.2E-93 T 29-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 CB4_RS05040 4ab1e141fdb793ccdfaa03a5f65a6f30 263 SUPERFAMILY SSF56784 6 261 4.52E-68 T 29-03-2018 IPR023214 HAD-like domain CB4_RS05040 4ab1e141fdb793ccdfaa03a5f65a6f30 263 Pfam PF13242 HAD-hyrolase-like 188 260 4.3E-19 T 29-03-2018 CB4_RS19805 53bc69dc1713628a3c4167fea904227a 266 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 73 137 2.2E-19 T 29-03-2018 CB4_RS19805 53bc69dc1713628a3c4167fea904227a 266 Gene3D G3DSA:3.30.1380.10 8 137 2.2E-32 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS19805 53bc69dc1713628a3c4167fea904227a 266 SUPERFAMILY SSF55166 9 137 9.42E-33 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS19805 53bc69dc1713628a3c4167fea904227a 266 Gene3D G3DSA:3.30.457.10 239 266 0.0063 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS14430 5523f66c50096a1c4f0e35820970dbdb 240 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 221 1.8E-60 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 SUPERFAMILY SSF81653 194 291 9.55E-28 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 Gene3D G3DSA:3.40.50.1000 520 662 2.4E-40 T 29-03-2018 IPR023214 HAD-like domain CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 Pfam PF00403 Heavy-metal-associated domain 5 55 2.2E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 SUPERFAMILY SSF81665 141 195 4.32E-19 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 SUPERFAMILY SSF81665 292 386 4.32E-19 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 SUPERFAMILY SSF81665 644 685 4.32E-19 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 141 697 2.4E-189 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 SUPERFAMILY SSF56784 449 694 2.06E-54 T 29-03-2018 IPR023214 HAD-like domain CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 SUPERFAMILY SSF56784 390 410 2.06E-54 T 29-03-2018 IPR023214 HAD-like domain CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 142 480 7.5E-99 T 29-03-2018 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 Pfam PF00122 E1-E2 ATPase 192 372 4.1E-56 T 29-03-2018 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 392 406 4.1E-22 T 29-03-2018 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 241 255 4.1E-22 T 29-03-2018 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 594 613 4.1E-22 T 29-03-2018 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 618 630 4.1E-22 T 29-03-2018 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 541 551 4.1E-22 T 29-03-2018 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 164 677 1.7E-92 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 123 696 3.6E-123 T 29-03-2018 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 SUPERFAMILY SSF55008 1 56 2.49E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00941 Cadmium-transporting ATPase signature 17 38 2.5E-73 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00941 Cadmium-transporting ATPase signature 276 290 2.5E-73 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00941 Cadmium-transporting ATPase signature 105 122 2.5E-73 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00941 Cadmium-transporting ATPase signature 6 15 2.5E-73 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00941 Cadmium-transporting ATPase signature 122 134 2.5E-73 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00941 Cadmium-transporting ATPase signature 196 212 2.5E-73 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00941 Cadmium-transporting ATPase signature 176 196 2.5E-73 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00941 Cadmium-transporting ATPase signature 257 273 2.5E-73 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 PRINTS PR00941 Cadmium-transporting ATPase signature 39 62 2.5E-73 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 394 400 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 Pfam PF00702 haloacid dehalogenase-like hydrolase 390 607 1.1E-46 T 29-03-2018 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 Gene3D G3DSA:3.40.1110.10 409 519 4.7E-31 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 Gene3D G3DSA:1.20.1110.10 131 408 1.0E-36 T 29-03-2018 CB4_RS12675 0a3bf7b402fbc140c508a141774ea381 702 Gene3D G3DSA:3.30.70.100 1 63 1.1E-12 T 29-03-2018 CB4_RS10465 266c1b8939366116446d5e1b50bd3d3c 218 Gene3D G3DSA:1.20.144.10 8 177 7.2E-31 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS10465 266c1b8939366116446d5e1b50bd3d3c 218 Pfam PF01569 PAP2 superfamily 61 172 2.8E-25 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS10465 266c1b8939366116446d5e1b50bd3d3c 218 SMART SM00014 62 168 2.2E-22 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS10465 266c1b8939366116446d5e1b50bd3d3c 218 SUPERFAMILY SSF48317 4 174 8.5E-43 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS14735 b14bc23cb4140aaa3a0ae8ee243bd065 153 Gene3D G3DSA:3.40.1550.10 1 153 2.0E-24 T 29-03-2018 IPR028976 CheC-like domain CB4_RS14735 b14bc23cb4140aaa3a0ae8ee243bd065 153 SUPERFAMILY SSF103039 4 133 2.75E-26 T 29-03-2018 IPR028976 CheC-like domain CB4_RS14735 b14bc23cb4140aaa3a0ae8ee243bd065 153 Pfam PF13690 Chemotaxis phosphatase CheX 42 137 1.6E-10 T 29-03-2018 IPR028051 Chemotaxis phosphatase CheX-like domain CB4_RS03990 f797bbe70b913ae264ee088256be4e78 296 SUPERFAMILY SSF50891 130 253 1.06E-20 T 29-03-2018 IPR029000 Cyclophilin-like domain CB4_RS03990 f797bbe70b913ae264ee088256be4e78 296 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 8 226 7.1E-46 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CB4_RS03990 f797bbe70b913ae264ee088256be4e78 296 SUPERFAMILY SSF160467 8 100 1.31E-16 T 29-03-2018 CB4_RS03990 f797bbe70b913ae264ee088256be4e78 296 Gene3D G3DSA:2.40.100.10 94 255 1.7E-31 T 29-03-2018 IPR029000 Cyclophilin-like domain CB4_RS03990 f797bbe70b913ae264ee088256be4e78 296 Gene3D G3DSA:3.30.1360.40 3 86 1.6E-14 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CB4_RS03990 f797bbe70b913ae264ee088256be4e78 296 SMART SM00796 7 237 8.5E-45 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CB4_RS02985 11ff1f4f9cf057fbcea244818f7a3799 134 SUPERFAMILY SSF46604 87 132 7.32E-8 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02985 11ff1f4f9cf057fbcea244818f7a3799 134 Gene3D G3DSA:2.60.15.10 1 89 1.7E-27 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02985 11ff1f4f9cf057fbcea244818f7a3799 134 Gene3D G3DSA:1.20.5.440 90 132 2.9E-17 T 29-03-2018 CB4_RS02985 11ff1f4f9cf057fbcea244818f7a3799 134 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 87 132 2.0E-18 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02985 11ff1f4f9cf057fbcea244818f7a3799 134 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 83 9.0E-19 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02985 11ff1f4f9cf057fbcea244818f7a3799 134 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 131 23.306 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02985 11ff1f4f9cf057fbcea244818f7a3799 134 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 132 1.7E-36 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02985 11ff1f4f9cf057fbcea244818f7a3799 134 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 6.5E-29 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02985 11ff1f4f9cf057fbcea244818f7a3799 134 SUPERFAMILY SSF51344 3 85 2.49E-24 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS00525 974733a2b0246fc2419693c0d1cf6476 151 SUPERFAMILY SSF111064 7 151 4.18E-52 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP CB4_RS00525 974733a2b0246fc2419693c0d1cf6476 151 Gene3D G3DSA:3.40.1510.10 6 151 1.1E-44 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP CB4_RS00525 974733a2b0246fc2419693c0d1cf6476 151 Pfam PF09021 HutP 9 149 1.7E-34 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP CB4_RS10815 66d30132ddce0027b1130a49b05222a8 276 SUPERFAMILY SSF52402 5 275 9.95E-82 T 29-03-2018 CB4_RS10815 66d30132ddce0027b1130a49b05222a8 276 Pfam PF02540 NAD synthase 25 267 6.4E-68 T 29-03-2018 IPR022310 NAD/GMP synthase CB4_RS10815 66d30132ddce0027b1130a49b05222a8 276 TIGRFAM TIGR00552 nadE: NAD+ synthetase 20 276 9.9E-72 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CB4_RS10815 66d30132ddce0027b1130a49b05222a8 276 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 19 270 31.794 T 29-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CB4_RS10815 66d30132ddce0027b1130a49b05222a8 276 Gene3D G3DSA:3.40.50.620 4 276 3.6E-63 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS03520 eaac4d3013d0f4d6ea5e4355d18fe8b2 283 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 15 217 7.7E-67 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS03520 eaac4d3013d0f4d6ea5e4355d18fe8b2 283 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 223 277 1.6E-23 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CB4_RS03520 eaac4d3013d0f4d6ea5e4355d18fe8b2 283 PIRSF PIRSF006483 6 283 4.9E-94 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 SUPERFAMILY SSF158472 195 244 4.05E-11 T 29-03-2018 CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 480 1.0E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 SMART SM00387 369 482 1.8E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 320 2.8E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 SUPERFAMILY SSF55874 312 483 1.96E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 Gene3D G3DSA:3.30.565.10 326 491 4.0E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 Gene3D G3DSA:1.10.287.130 238 318 4.0E-15 T 29-03-2018 CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 460 6.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 421 6.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 435 6.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 479 6.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 SUPERFAMILY SSF47384 241 322 7.85E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 Pfam PF00672 HAMP domain 195 243 1.2E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 SMART SM00304 195 247 1.3E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS13520 d8e3712234518ab7ece328124bcad0fb 496 SMART SM00388 255 322 4.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS07865 4973a33ea2b4c2fd60528a2d248e7ef7 104 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 35 100 1.3E-8 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CB4_RS07865 4973a33ea2b4c2fd60528a2d248e7ef7 104 Gene3D G3DSA:1.10.760.10 22 104 2.6E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CB4_RS07865 4973a33ea2b4c2fd60528a2d248e7ef7 104 SUPERFAMILY SSF46626 8 103 1.08E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CB4_RS14260 e9b650948e8c8852dc4291f959898918 242 SUPERFAMILY SSF88713 38 238 5.56E-66 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS14260 e9b650948e8c8852dc4291f959898918 242 Gene3D G3DSA:3.20.20.370 20 241 5.8E-62 T 29-03-2018 CB4_RS14260 e9b650948e8c8852dc4291f959898918 242 Pfam PF01522 Polysaccharide deacetylase 44 163 2.0E-36 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS01375 9f5a95466d30b09f49d9d8e78d5d1af9 291 Gene3D G3DSA:3.55.30.10 2 234 2.6E-73 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CB4_RS01375 9f5a95466d30b09f49d9d8e78d5d1af9 291 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 38.193 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CB4_RS01375 9f5a95466d30b09f49d9d8e78d5d1af9 291 SUPERFAMILY SSF118352 233 288 8.11E-19 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CB4_RS01375 9f5a95466d30b09f49d9d8e78d5d1af9 291 PIRSF PIRSF005261 1 290 6.1E-73 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CB4_RS01375 9f5a95466d30b09f49d9d8e78d5d1af9 291 SUPERFAMILY SSF64397 2 240 2.49E-73 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CB4_RS01375 9f5a95466d30b09f49d9d8e78d5d1af9 291 Pfam PF01430 Hsp33 protein 3 280 1.6E-86 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CB4_RS01375 9f5a95466d30b09f49d9d8e78d5d1af9 291 Gene3D G3DSA:3.90.1280.10 235 288 1.4E-21 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CB4_RS07460 61b190569dede6bc800fe383833d0b40 248 Gene3D G3DSA:3.40.50.300 1 213 6.5E-60 T 29-03-2018 CB4_RS07460 61b190569dede6bc800fe383833d0b40 248 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS07460 61b190569dede6bc800fe383833d0b40 248 SUPERFAMILY SSF52540 2 209 6.29E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07460 61b190569dede6bc800fe383833d0b40 248 SMART SM00382 28 208 1.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS07460 61b190569dede6bc800fe383833d0b40 248 Pfam PF00005 ABC transporter 19 158 5.7E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS08480 9f07c278013c2297bd9c55ca615cb759 809 Pfam PF00271 Helicase conserved C-terminal domain 565 666 1.8E-8 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS08480 9f07c278013c2297bd9c55ca615cb759 809 Gene3D G3DSA:3.40.50.300 269 437 2.4E-26 T 29-03-2018 CB4_RS08480 9f07c278013c2297bd9c55ca615cb759 809 SUPERFAMILY SSF52540 269 455 2.04E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08480 9f07c278013c2297bd9c55ca615cb759 809 SMART SM00487 268 464 1.5E-20 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS08480 9f07c278013c2297bd9c55ca615cb759 809 SUPERFAMILY SSF52540 534 713 7.79E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08480 9f07c278013c2297bd9c55ca615cb759 809 SMART SM00490 570 667 3.5E-11 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS08480 9f07c278013c2297bd9c55ca615cb759 809 Gene3D G3DSA:3.40.50.300 476 709 1.4E-22 T 29-03-2018 CB4_RS08480 9f07c278013c2297bd9c55ca615cb759 809 TIGRFAM TIGR00595 priA: primosomal protein N' 296 805 3.6E-210 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CB4_RS08480 9f07c278013c2297bd9c55ca615cb759 809 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 808 25.127 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CB4_RS08480 9f07c278013c2297bd9c55ca615cb759 809 Pfam PF00270 DEAD/DEAH box helicase 275 438 4.3E-14 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS02875 627dd2f9f99d9c182f7ada2677655daf 348 SUPERFAMILY SSF55821 20 215 3.36E-64 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CB4_RS02875 627dd2f9f99d9c182f7ada2677655daf 348 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 20 213 1.0E-59 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CB4_RS02875 627dd2f9f99d9c182f7ada2677655daf 348 Gene3D G3DSA:3.90.870.10 11 218 1.7E-75 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CB4_RS02875 627dd2f9f99d9c182f7ada2677655daf 348 Pfam PF01300 Telomere recombination 27 202 1.6E-53 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CB4_RS02875 627dd2f9f99d9c182f7ada2677655daf 348 Pfam PF03481 Putative GTP-binding controlling metal-binding 204 344 1.6E-26 T 29-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CB4_RS02875 627dd2f9f99d9c182f7ada2677655daf 348 Gene3D G3DSA:3.40.50.2000 256 342 3.7E-4 T 29-03-2018 CB4_RS02875 627dd2f9f99d9c182f7ada2677655daf 348 PIRSF PIRSF004930 1 348 5.2E-119 T 29-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 Gene3D G3DSA:3.40.50.10860 1 144 1.6E-52 T 29-03-2018 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 SMART SM00839 144 351 1.5E-74 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 PIRSF PIRSF000188 1 353 5.2E-165 T 29-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 Gene3D G3DSA:3.40.50.720 145 362 5.1E-40 T 29-03-2018 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 148 200 3.1E-6 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 219 298 4.7E-9 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 SUPERFAMILY SSF53223 4 143 3.84E-47 T 29-03-2018 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 SUPERFAMILY SSF51735 141 349 2.93E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 24 130 3.2E-25 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 8.2E-21 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 8.2E-21 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 8.2E-21 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS16390 3dd763727619c217d538eb19d5e58871 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 8.2E-21 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS00425 0db87056cfc5ea122f50d7e8f8d899c3 310 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 53 6.0E-16 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CB4_RS00425 0db87056cfc5ea122f50d7e8f8d899c3 310 Pfam PF12727 PBP superfamily domain 98 282 1.2E-60 T 29-03-2018 IPR024370 PBP domain CB4_RS00425 0db87056cfc5ea122f50d7e8f8d899c3 310 Gene3D G3DSA:1.10.10.10 8 62 2.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00425 0db87056cfc5ea122f50d7e8f8d899c3 310 Gene3D G3DSA:3.40.190.10 161 249 2.6E-5 T 29-03-2018 CB4_RS00425 0db87056cfc5ea122f50d7e8f8d899c3 310 Pfam PF12728 Helix-turn-helix domain 7 55 2.5E-14 T 29-03-2018 CB4_RS00425 0db87056cfc5ea122f50d7e8f8d899c3 310 SUPERFAMILY SSF53850 86 297 2.95E-14 T 29-03-2018 CB4_RS17850 73403e17a199be9dd9738ac40cc793a3 541 SUPERFAMILY SSF51569 2 293 1.52E-86 T 29-03-2018 CB4_RS17850 73403e17a199be9dd9738ac40cc793a3 541 SMART SM00917 375 518 3.4E-42 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS17850 73403e17a199be9dd9738ac40cc793a3 541 Pfam PF08502 LeuA allosteric (dimerisation) domain 376 517 1.6E-29 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS17850 73403e17a199be9dd9738ac40cc793a3 541 Pfam PF00682 HMGL-like 5 275 3.5E-46 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CB4_RS17850 73403e17a199be9dd9738ac40cc793a3 541 SUPERFAMILY SSF110921 398 514 4.97E-23 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS17850 73403e17a199be9dd9738ac40cc793a3 541 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS17850 73403e17a199be9dd9738ac40cc793a3 541 Gene3D G3DSA:3.20.20.70 1 349 9.4E-107 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS17850 73403e17a199be9dd9738ac40cc793a3 541 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 5 524 2.0E-237 T 29-03-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 CB4_RS15180 778a2f86df0bed0c649da11b8a24ddca 244 Gene3D G3DSA:3.40.50.150 2 237 6.2E-38 T 29-03-2018 CB4_RS15180 778a2f86df0bed0c649da11b8a24ddca 244 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 14 238 2.2E-73 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CB4_RS15180 778a2f86df0bed0c649da11b8a24ddca 244 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 146 160 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CB4_RS15180 778a2f86df0bed0c649da11b8a24ddca 244 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 5 238 34.311 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CB4_RS15180 778a2f86df0bed0c649da11b8a24ddca 244 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 25 40 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CB4_RS15180 778a2f86df0bed0c649da11b8a24ddca 244 SUPERFAMILY SSF53335 4 230 2.13E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS15180 778a2f86df0bed0c649da11b8a24ddca 244 Pfam PF01209 ubiE/COQ5 methyltransferase family 9 238 3.7E-82 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CB4_RS13795 127d294d07a120e3049e90c3c31261d4 624 SUPERFAMILY SSF69318 339 606 2.44E-26 T 29-03-2018 CB4_RS13795 127d294d07a120e3049e90c3c31261d4 624 Gene3D G3DSA:2.130.10.130 474 615 7.0E-13 T 29-03-2018 CB4_RS13795 127d294d07a120e3049e90c3c31261d4 624 Gene3D G3DSA:2.60.40.680 334 419 0.39 T 29-03-2018 CB4_RS13795 127d294d07a120e3049e90c3c31261d4 624 SUPERFAMILY SSF88713 58 217 4.45E-6 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS13795 127d294d07a120e3049e90c3c31261d4 624 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 35 281 3.2E-46 T 29-03-2018 IPR018763 Protein of unknown function DUF2334 CB4_RS13795 127d294d07a120e3049e90c3c31261d4 624 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 400 460 1.4E-10 T 29-03-2018 CB4_RS13795 127d294d07a120e3049e90c3c31261d4 624 Gene3D G3DSA:3.20.20.370 31 333 7.0E-11 T 29-03-2018 CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 401 3.6E-139 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 Gene3D G3DSA:3.30.70.260 244 324 8.5E-19 T 29-03-2018 CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 PIRSF PIRSF000726 53 409 6.2E-125 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 PIRSF PIRSF000726 1 61 5.3E-21 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 Gene3D G3DSA:3.40.1160.10 1 243 1.2E-73 T 29-03-2018 CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 Pfam PF00696 Amino acid kinase family 3 230 4.8E-56 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 Gene3D G3DSA:3.30.70.260 325 401 1.3E-18 T 29-03-2018 CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 SUPERFAMILY SSF55021 329 403 2.26E-21 T 29-03-2018 CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 401 2.6E-118 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 SUPERFAMILY SSF53633 4 242 7.99E-76 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 Pfam PF13840 ACT domain 335 397 1.0E-16 T 29-03-2018 IPR027795 GATS-like ACT domain CB4_RS05520 6b4635b537f0749d6edeb2ad72df724a 414 SUPERFAMILY SSF55021 249 325 1.14E-15 T 29-03-2018 CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 SUPERFAMILY SSF69742 1 158 3.27E-49 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 2.0E-44 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 29.993 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 PIRSF PIRSF000445 1 434 1.6E-155 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 323 419 3.3E-18 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 2.1E-49 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 SUPERFAMILY SSF51735 162 314 1.16E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 Gene3D G3DSA:1.10.1200.70 332 420 1.1E-18 T 29-03-2018 CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 SUPERFAMILY SSF69075 317 420 1.44E-16 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 419 1.3E-146 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CB4_RS05660 43acd39a50c9e6910adcdda3ca18d084 452 Gene3D G3DSA:3.40.50.720 161 313 3.4E-28 T 29-03-2018 CB4_RS03925 d1d861b634260edff2d884dcbc91ecc6 343 SUPERFAMILY SSF141868 102 338 4.18E-56 T 29-03-2018 IPR001633 EAL domain CB4_RS03925 d1d861b634260edff2d884dcbc91ecc6 343 Pfam PF00563 EAL domain 107 335 5.9E-49 T 29-03-2018 IPR001633 EAL domain CB4_RS03925 d1d861b634260edff2d884dcbc91ecc6 343 SMART SM00052 95 340 4.3E-26 T 29-03-2018 IPR001633 EAL domain CB4_RS03925 d1d861b634260edff2d884dcbc91ecc6 343 Gene3D G3DSA:3.20.20.450 92 340 2.5E-56 T 29-03-2018 IPR001633 EAL domain CB4_RS19825 5cd7ad47dc38d465ee02da4c80c9ffa1 1168 SUPERFAMILY SSF49265 938 1025 2.73E-7 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CB4_RS19825 5cd7ad47dc38d465ee02da4c80c9ffa1 1168 Gene3D G3DSA:2.60.40.10 842 939 3.3E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS19825 5cd7ad47dc38d465ee02da4c80c9ffa1 1168 SUPERFAMILY SSF49265 848 915 5.78E-5 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CB4_RS19825 5cd7ad47dc38d465ee02da4c80c9ffa1 1168 Gene3D G3DSA:2.60.40.10 940 1033 6.3E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS20415 0c8ca92adbb1890d99cdf14a3decfc87 365 SUPERFAMILY SSF52172 17 185 2.56E-44 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS20415 0c8ca92adbb1890d99cdf14a3decfc87 365 Pfam PF00072 Response regulator receiver domain 20 130 5.4E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS20415 0c8ca92adbb1890d99cdf14a3decfc87 365 Pfam PF13487 HD domain 241 304 3.6E-18 T 29-03-2018 CB4_RS20415 0c8ca92adbb1890d99cdf14a3decfc87 365 SMART SM00471 186 323 5.5E-5 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS20415 0c8ca92adbb1890d99cdf14a3decfc87 365 Gene3D G3DSA:3.40.50.2300 10 173 1.3E-42 T 29-03-2018 CB4_RS20415 0c8ca92adbb1890d99cdf14a3decfc87 365 SMART SM00448 18 130 1.3E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS20415 0c8ca92adbb1890d99cdf14a3decfc87 365 SUPERFAMILY SSF109604 178 353 2.54E-40 T 29-03-2018 CB4_RS20415 0c8ca92adbb1890d99cdf14a3decfc87 365 Gene3D G3DSA:1.10.3210.10 174 364 1.0E-50 T 29-03-2018 CB4_RS09570 da17d6d2aaa152cc61f438136ffcef0b 250 Gene3D G3DSA:1.10.1270.10 86 143 0.0031 T 29-03-2018 CB4_RS09570 da17d6d2aaa152cc61f438136ffcef0b 250 Gene3D G3DSA:3.90.1530.10 3 85 0.0017 T 29-03-2018 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 465 2.2E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 SMART SM00304 189 241 1.9E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 SMART SM00387 354 467 4.9E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 Pfam PF00672 HAMP domain 190 237 1.1E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 SMART SM00388 242 309 2.8E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 Gene3D G3DSA:3.30.450.20 33 162 2.3E-11 T 29-03-2018 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 Gene3D G3DSA:3.30.565.10 313 473 2.6E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 SUPERFAMILY SSF55874 299 469 3.14E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 SUPERFAMILY SSF158472 190 238 1.06E-9 T 29-03-2018 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 2.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 464 2.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 420 2.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 2.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 SUPERFAMILY SSF47384 225 308 2.35E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 308 1.6E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS10320 a58c04d08fb1110679e70ab32ef9258f 473 Gene3D G3DSA:1.10.287.130 232 305 1.8E-22 T 29-03-2018 CB4_RS19890 9a0ce6dce6ce4b8055ee277478499f37 208 Gene3D G3DSA:3.40.109.10 2 208 1.3E-35 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS19890 9a0ce6dce6ce4b8055ee277478499f37 208 SUPERFAMILY SSF55469 1 202 1.24E-41 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS19890 9a0ce6dce6ce4b8055ee277478499f37 208 Pfam PF00881 Nitroreductase family 8 185 2.8E-25 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CB4_RS05315 e62ae6f08afa592c7bcb3a169a97e231 329 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 5.6E-78 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CB4_RS05315 e62ae6f08afa592c7bcb3a169a97e231 329 Gene3D G3DSA:1.10.1040.10 70 329 1.0E-115 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CB4_RS05315 e62ae6f08afa592c7bcb3a169a97e231 329 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 44.846 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CB4_RS05315 e62ae6f08afa592c7bcb3a169a97e231 329 PIRSF PIRSF000116 201 329 7.9E-14 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CB4_RS05315 e62ae6f08afa592c7bcb3a169a97e231 329 PIRSF PIRSF000116 3 205 2.4E-47 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CB4_RS05315 e62ae6f08afa592c7bcb3a169a97e231 329 Gene3D G3DSA:3.40.50.720 2 69 2.9E-4 T 29-03-2018 CB4_RS05315 e62ae6f08afa592c7bcb3a169a97e231 329 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 7.8E-144 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CB4_RS05315 e62ae6f08afa592c7bcb3a169a97e231 329 SUPERFAMILY SSF48179 183 327 2.72E-67 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS05315 e62ae6f08afa592c7bcb3a169a97e231 329 SUPERFAMILY SSF51735 3 182 1.75E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS05315 e62ae6f08afa592c7bcb3a169a97e231 329 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 8.9E-65 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 7.4E-83 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 SUPERFAMILY SSF142695 203 374 1.11E-75 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 37.866 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 9.0E-76 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 397 42.79 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 Gene3D G3DSA:3.90.870.10 1 210 2.8E-92 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 SUPERFAMILY SSF55821 2 204 8.7E-83 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 PIRSF PIRSF001259 1 397 6.1E-187 T 29-03-2018 CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 Pfam PF00925 GTP cyclohydrolase II 206 371 5.2E-78 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 206 395 1.7E-83 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CB4_RS16030 9eaf2e9eee2e2f8d4fe767cf6192bba1 397 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 393 55.733 T 29-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CB4_RS02345 ca470d0917e0d36b4c316d1c54f6cf62 161 Gene3D G3DSA:3.10.20.80 1 70 8.9E-20 T 29-03-2018 CB4_RS02345 ca470d0917e0d36b4c316d1c54f6cf62 161 SUPERFAMILY SSF54364 2 70 5.23E-15 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CB4_RS02345 ca470d0917e0d36b4c316d1c54f6cf62 161 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 80 160 3.3E-15 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CB4_RS02345 ca470d0917e0d36b4c316d1c54f6cf62 161 Gene3D G3DSA:3.30.110.10 71 161 2.2E-17 T 29-03-2018 CB4_RS02345 ca470d0917e0d36b4c316d1c54f6cf62 161 SUPERFAMILY SSF55200 80 160 2.22E-14 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CB4_RS02345 ca470d0917e0d36b4c316d1c54f6cf62 161 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 3 68 1.3E-17 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CB4_RS02345 ca470d0917e0d36b4c316d1c54f6cf62 161 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 3 161 7.9E-33 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CB4_RS12505 2a4895d7a12880c8b166dc158ef2bb0f 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 220 7.6E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS12505 2a4895d7a12880c8b166dc158ef2bb0f 225 Gene3D G3DSA:3.40.50.2300 1 124 4.0E-35 T 29-03-2018 CB4_RS12505 2a4895d7a12880c8b166dc158ef2bb0f 225 SUPERFAMILY SSF52172 1 166 1.03E-41 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS12505 2a4895d7a12880c8b166dc158ef2bb0f 225 Pfam PF00072 Response regulator receiver domain 4 109 2.6E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS12505 2a4895d7a12880c8b166dc158ef2bb0f 225 SMART SM00862 145 220 4.9E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS12505 2a4895d7a12880c8b166dc158ef2bb0f 225 Gene3D G3DSA:1.10.10.10 125 225 5.8E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12505 2a4895d7a12880c8b166dc158ef2bb0f 225 SMART SM00448 2 112 3.5E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS00025 ef896f1254243c78dce053109ba65825 335 Gene3D G3DSA:3.40.47.10 49 247 3.2E-10 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS00025 ef896f1254243c78dce053109ba65825 335 PIRSF PIRSF011570 1 335 1.3E-159 T 29-03-2018 IPR010894 Stage V sporulation AD CB4_RS00025 ef896f1254243c78dce053109ba65825 335 SUPERFAMILY SSF53901 56 250 4.37E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS00025 ef896f1254243c78dce053109ba65825 335 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 333 5.1E-156 T 29-03-2018 IPR010894 Stage V sporulation AD CB4_RS00025 ef896f1254243c78dce053109ba65825 335 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 333 9.6E-155 T 29-03-2018 IPR010894 Stage V sporulation AD CB4_RS08330 ae0875fbf1019a8adf81fb4dc4b149ef 274 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 30 269 3.8E-76 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CB4_RS08330 ae0875fbf1019a8adf81fb4dc4b149ef 274 SUPERFAMILY SSF64438 21 272 4.03E-81 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CB4_RS08330 ae0875fbf1019a8adf81fb4dc4b149ef 274 Gene3D G3DSA:3.60.140.10 5 274 7.4E-85 T 29-03-2018 CB4_RS08330 ae0875fbf1019a8adf81fb4dc4b149ef 274 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 37 271 2.2E-58 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 191 0.0058 T 29-03-2018 CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 Gene3D G3DSA:3.40.50.720 7 231 5.4E-63 T 29-03-2018 CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 SUPERFAMILY SSF51735 4 229 3.27E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.9E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.9E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.9E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.9E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.9E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 2.9E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 Pfam PF00106 short chain dehydrogenase 10 194 2.7E-61 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS15905 6165d5574ac374d37f67d05dcb5830ab 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS19835 6d629c32f808f051e2776824337e4d5f 105 SUPERFAMILY SSF52833 7 101 1.11E-15 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS19835 6d629c32f808f051e2776824337e4d5f 105 Gene3D G3DSA:3.40.30.10 1 104 1.0E-11 T 29-03-2018 CB4_RS19835 6d629c32f808f051e2776824337e4d5f 105 Pfam PF00085 Thioredoxin 14 87 1.5E-6 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 SMART SM00304 299 351 2.1E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 SMART SM00304 596 652 24.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 SUPERFAMILY SSF58104 386 654 1.22E-72 T 29-03-2018 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 SUPERFAMILY SSF58104 319 353 1.22E-72 T 29-03-2018 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 Pfam PF02743 Cache domain 49 261 1.1E-27 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 Gene3D G3DSA:3.30.450.20 167 275 3.0E-18 T 29-03-2018 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 428 607 6.8E-44 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 SUPERFAMILY SSF103190 94 188 6.83E-13 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 Gene3D G3DSA:1.20.1480.30 296 412 0.057 T 29-03-2018 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 Pfam PF00672 HAMP domain 299 347 1.4E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 Gene3D G3DSA:1.10.287.950 413 656 4.0E-54 T 29-03-2018 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 SMART SM00283 380 655 6.3E-73 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14270 887018c1dce2fc13031764ced052d4ef 656 Gene3D G3DSA:3.30.450.20 35 166 1.6E-19 T 29-03-2018 CB4_RS08355 7cc5750c74478dbb3706e058cf19119e 164 Pfam PF05103 DivIVA protein 3 133 4.4E-48 T 29-03-2018 IPR007793 DivIVA family CB4_RS08355 7cc5750c74478dbb3706e058cf19119e 164 Gene3D G3DSA:1.20.5.620 84 142 0.0022 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CB4_RS08355 7cc5750c74478dbb3706e058cf19119e 164 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 3.9E-17 T 29-03-2018 IPR019933 DivIVA domain CB4_RS02100 61e7b6fcdab42ba564e1890906ec75bb 383 SUPERFAMILY SSF63829 328 372 7.41E-53 T 29-03-2018 CB4_RS02100 61e7b6fcdab42ba564e1890906ec75bb 383 SUPERFAMILY SSF63829 42 292 7.41E-53 T 29-03-2018 CB4_RS02100 61e7b6fcdab42ba564e1890906ec75bb 383 Gene3D G3DSA:2.120.10.30 51 157 3.5E-9 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS02100 61e7b6fcdab42ba564e1890906ec75bb 383 Gene3D G3DSA:2.120.10.30 158 373 5.7E-30 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS02100 61e7b6fcdab42ba564e1890906ec75bb 383 Pfam PF03088 Strictosidine synthase 174 259 3.1E-24 T 29-03-2018 IPR018119 Strictosidine synthase, conserved region GO:0009058|GO:0016844 CB4_RS02095 6b1cc59292658352632889030d95fd99 337 SUPERFAMILY SSF50129 1 161 2.13E-39 T 29-03-2018 IPR011032 GroES-like CB4_RS02095 6b1cc59292658352632889030d95fd99 337 SUPERFAMILY SSF51735 136 311 2.19E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS02095 6b1cc59292658352632889030d95fd99 337 Gene3D G3DSA:3.90.180.10 1 337 6.0E-83 T 29-03-2018 CB4_RS02095 6b1cc59292658352632889030d95fd99 337 SMART SM00829 11 335 9.5E-15 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CB4_RS02095 6b1cc59292658352632889030d95fd99 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 128 1.0E-11 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CB4_RS02095 6b1cc59292658352632889030d95fd99 337 Pfam PF00107 Zinc-binding dehydrogenase 171 299 9.2E-26 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 334 171.51 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 SMART SM00382 53 181 3.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 11 237 1.8E-117 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 Gene3D G3DSA:1.10.10.10 259 329 4.4E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 Gene3D G3DSA:1.10.8.60 186 256 3.4E-31 T 29-03-2018 CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 SUPERFAMILY SSF52540 22 256 2.89E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 255 328 4.7E-32 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 Gene3D G3DSA:3.40.50.300 20 183 2.8E-28 T 29-03-2018 CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 SUPERFAMILY SSF46785 258 332 1.02E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 26 328 2.1E-146 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CB4_RS05935 f5eb89b10a379d9fbbdeda57fbcb0f92 334 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 333 7.0E-30 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CB4_RS06740 d314fdf8cced8f504716ab16eaf24b1d 222 Pfam PF01791 DeoC/LacD family aldolase 6 212 2.8E-21 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CB4_RS06740 d314fdf8cced8f504716ab16eaf24b1d 222 PIRSF PIRSF001357 1 220 7.6E-79 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CB4_RS06740 d314fdf8cced8f504716ab16eaf24b1d 222 SUPERFAMILY SSF51569 3 214 1.67E-83 T 29-03-2018 CB4_RS06740 d314fdf8cced8f504716ab16eaf24b1d 222 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 3 217 37.408 T 29-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CB4_RS06740 d314fdf8cced8f504716ab16eaf24b1d 222 Gene3D G3DSA:3.20.20.70 1 221 3.9E-99 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS06740 d314fdf8cced8f504716ab16eaf24b1d 222 SMART SM01133 4 215 3.8E-104 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CB4_RS06740 d314fdf8cced8f504716ab16eaf24b1d 222 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 5 213 1.3E-88 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 467 60.191 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 Gene3D G3DSA:3.30.499.10 1 155 5.5E-42 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 Gene3D G3DSA:3.40.1060.10 156 289 4.6E-44 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 465 5.6E-240 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 SUPERFAMILY SSF53732 2 472 9.42E-167 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 PRINTS PR00415 Aconitase family signature 196 209 4.7E-44 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 PRINTS PR00415 Aconitase family signature 210 223 4.7E-44 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 PRINTS PR00415 Aconitase family signature 400 413 4.7E-44 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 PRINTS PR00415 Aconitase family signature 287 301 4.7E-44 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 PRINTS PR00415 Aconitase family signature 109 117 4.7E-44 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 PRINTS PR00415 Aconitase family signature 134 149 4.7E-44 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 PRINTS PR00415 Aconitase family signature 83 96 4.7E-44 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 PRINTS PR00415 Aconitase family signature 120 133 4.7E-44 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 PRINTS PR00415 Aconitase family signature 344 355 4.7E-44 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 Pfam PF00330 Aconitase family (aconitate hydratase) 8 458 2.8E-159 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10750 c5bfe24ee5b96387a1ba68d9e1da1971 479 Gene3D G3DSA:3.30.499.10 308 478 1.7E-52 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS11670 2a9102d3e853fb037106e449f7232430 635 Gene3D G3DSA:3.40.50.300 1 204 2.3E-15 T 29-03-2018 CB4_RS11670 2a9102d3e853fb037106e449f7232430 635 Gene3D G3DSA:1.20.1170.10 288 520 9.3E-9 T 29-03-2018 CB4_RS11670 2a9102d3e853fb037106e449f7232430 635 SUPERFAMILY SSF75712 291 372 1.01E-7 T 29-03-2018 CB4_RS11670 2a9102d3e853fb037106e449f7232430 635 Pfam PF13476 AAA domain 6 183 1.2E-8 T 29-03-2018 CB4_RS11670 2a9102d3e853fb037106e449f7232430 635 SUPERFAMILY SSF52540 551 587 3.19E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11670 2a9102d3e853fb037106e449f7232430 635 SUPERFAMILY SSF52540 1 141 3.19E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13255 d8c581b63ae5107c9fa6f6fd9bb3b69a 619 SUPERFAMILY SSF52540 371 613 8.95E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13255 d8c581b63ae5107c9fa6f6fd9bb3b69a 619 Pfam PF00664 ABC transporter transmembrane region 50 332 1.1E-60 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS13255 d8c581b63ae5107c9fa6f6fd9bb3b69a 619 Gene3D G3DSA:1.20.1560.10 21 363 7.0E-101 T 29-03-2018 CB4_RS13255 d8c581b63ae5107c9fa6f6fd9bb3b69a 619 ProSitePatterns PS00211 ABC transporters family signature. 514 528 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS13255 d8c581b63ae5107c9fa6f6fd9bb3b69a 619 SUPERFAMILY SSF90123 33 361 1.44E-89 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS13255 d8c581b63ae5107c9fa6f6fd9bb3b69a 619 SMART SM00382 402 594 8.9E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13255 d8c581b63ae5107c9fa6f6fd9bb3b69a 619 Gene3D G3DSA:3.40.50.300 364 618 3.6E-75 T 29-03-2018 CB4_RS13255 d8c581b63ae5107c9fa6f6fd9bb3b69a 619 Pfam PF00005 ABC transporter 394 542 4.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS18310 7012963e219aef443f7949a9b2f71094 373 SMART SM00729 54 277 0.0063 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS18310 7012963e219aef443f7949a9b2f71094 373 PIRSF PIRSF004762 1 367 5.2E-98 T 29-03-2018 CB4_RS18310 7012963e219aef443f7949a9b2f71094 373 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 51 356 5.5E-100 T 29-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CB4_RS18310 7012963e219aef443f7949a9b2f71094 373 SUPERFAMILY SSF102114 13 348 8.11E-53 T 29-03-2018 CB4_RS18310 7012963e219aef443f7949a9b2f71094 373 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 13 359 49.568 T 29-03-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CB4_RS18310 7012963e219aef443f7949a9b2f71094 373 Gene3D G3DSA:3.20.20.70 1 358 1.7E-50 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS18310 7012963e219aef443f7949a9b2f71094 373 Pfam PF04055 Radical SAM superfamily 59 226 4.2E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS18310 7012963e219aef443f7949a9b2f71094 373 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 14 355 1.2E-144 T 29-03-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CB4_RS14685 5e2c424bdd86c9c002641e390140d837 490 SUPERFAMILY SSF53720 3 479 3.4E-177 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS14685 5e2c424bdd86c9c002641e390140d837 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CB4_RS14685 5e2c424bdd86c9c002641e390140d837 490 Gene3D G3DSA:3.40.309.10 265 462 5.1E-77 T 29-03-2018 CB4_RS14685 5e2c424bdd86c9c002641e390140d837 490 Gene3D G3DSA:3.40.605.10 1 264 2.9E-104 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS14685 5e2c424bdd86c9c002641e390140d837 490 Pfam PF00171 Aldehyde dehydrogenase family 12 476 1.0E-183 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS14685 5e2c424bdd86c9c002641e390140d837 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CB4_RS16225 5cde1631ed0f12c7de1833bbd58ede4a 402 Pfam PF14286 DHHW protein 37 100 1.2E-7 T 29-03-2018 IPR025945 DHHW protein CB4_RS16225 5cde1631ed0f12c7de1833bbd58ede4a 402 Pfam PF14286 DHHW protein 194 357 7.8E-14 T 29-03-2018 IPR025945 DHHW protein CB4_RS16225 5cde1631ed0f12c7de1833bbd58ede4a 402 Gene3D G3DSA:3.40.50.1110 16 226 2.8E-4 T 29-03-2018 CB4_RS20385 667c1884b494529f63e8529d8eb7826f 239 Gene3D G3DSA:3.30.470.20 94 221 5.5E-52 T 29-03-2018 CB4_RS20385 667c1884b494529f63e8529d8eb7826f 239 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20385 667c1884b494529f63e8529d8eb7826f 239 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 5 236 3.6E-80 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CB4_RS20385 667c1884b494529f63e8529d8eb7826f 239 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 235 35.166 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20385 667c1884b494529f63e8529d8eb7826f 239 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20385 667c1884b494529f63e8529d8eb7826f 239 Pfam PF01259 SAICAR synthetase 7 232 4.0E-69 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20385 667c1884b494529f63e8529d8eb7826f 239 SUPERFAMILY SSF56104 2 237 4.25E-87 T 29-03-2018 CB4_RS20385 667c1884b494529f63e8529d8eb7826f 239 Gene3D G3DSA:3.30.200.20 1 93 1.1E-27 T 29-03-2018 CB4_RS12585 d8e9757de9441cef18573e78174dbf79 171 Gene3D G3DSA:3.40.630.30 3 151 0.0014 T 29-03-2018 CB4_RS13875 d4f06dc79c3283334f1571baad05a609 538 SUPERFAMILY SSF52540 296 528 9.28E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13875 d4f06dc79c3283334f1571baad05a609 538 SMART SM00382 344 513 0.0068 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13875 d4f06dc79c3283334f1571baad05a609 538 SMART SM00382 26 238 2.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13875 d4f06dc79c3283334f1571baad05a609 538 SUPERFAMILY SSF52540 125 254 3.34E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13875 d4f06dc79c3283334f1571baad05a609 538 SUPERFAMILY SSF52540 2 92 3.34E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13875 d4f06dc79c3283334f1571baad05a609 538 Pfam PF00005 ABC transporter 18 184 8.3E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS13875 d4f06dc79c3283334f1571baad05a609 538 Pfam PF00005 ABC transporter 335 467 3.5E-15 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS13875 d4f06dc79c3283334f1571baad05a609 538 Gene3D G3DSA:3.40.50.300 285 537 8.1E-40 T 29-03-2018 CB4_RS13875 d4f06dc79c3283334f1571baad05a609 538 Pfam PF12848 ABC transporter 224 309 2.0E-20 T 29-03-2018 IPR032781 ABC-transporter extension domain CB4_RS13875 d4f06dc79c3283334f1571baad05a609 538 Gene3D G3DSA:3.40.50.300 1 284 2.4E-56 T 29-03-2018 CB4_RS05955 f8789a01082cbddcf446a56de8ba2707 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.338 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CB4_RS05955 f8789a01082cbddcf446a56de8ba2707 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2 342 1.0E-139 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CB4_RS05955 f8789a01082cbddcf446a56de8ba2707 342 SUPERFAMILY SSF111337 2 342 4.45E-137 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CB4_RS05955 f8789a01082cbddcf446a56de8ba2707 342 Pfam PF02547 Queuosine biosynthesis protein 3 341 1.2E-139 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CB4_RS05955 f8789a01082cbddcf446a56de8ba2707 342 Gene3D G3DSA:3.40.1780.10 173 342 6.5E-66 T 29-03-2018 CB4_RS05955 f8789a01082cbddcf446a56de8ba2707 342 Gene3D G3DSA:3.40.1780.10 1 133 2.4E-37 T 29-03-2018 CB4_RS09390 f616d9d9db0729722b7a08fb5cae1fe4 391 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 273 280 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS09390 f616d9d9db0729722b7a08fb5cae1fe4 391 Pfam PF02655 ATP-grasp domain 115 282 1.2E-9 T 29-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 CB4_RS09390 f616d9d9db0729722b7a08fb5cae1fe4 391 SUPERFAMILY SSF56059 97 290 1.16E-21 T 29-03-2018 CB4_RS09390 f616d9d9db0729722b7a08fb5cae1fe4 391 Gene3D G3DSA:3.30.470.20 117 367 4.6E-25 T 29-03-2018 CB4_RS09390 f616d9d9db0729722b7a08fb5cae1fe4 391 Gene3D G3DSA:3.40.50.20 1 116 1.0E-13 T 29-03-2018 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 Pfam PF06130 Phosphate propanoyltransferase 113 178 9.4E-16 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 Pfam PF06130 Phosphate propanoyltransferase 4 83 2.5E-30 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 SUPERFAMILY SSF53067 202 362 1.1E-58 T 29-03-2018 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 374 391 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 Hamap MF_00020 Acetate kinase [ackA]. 201 570 143.613 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 TIGRFAM TIGR00016 ackA: acetate kinase 251 567 5.0E-124 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 Gene3D G3DSA:3.30.420.40 202 366 2.8E-59 T 29-03-2018 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 PRINTS PR00471 Acetate kinase family signature 494 510 4.7E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 PRINTS PR00471 Acetate kinase family signature 203 214 4.7E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 PRINTS PR00471 Acetate kinase family signature 472 485 4.7E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 PRINTS PR00471 Acetate kinase family signature 548 560 4.7E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 PRINTS PR00471 Acetate kinase family signature 374 395 4.7E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 PRINTS PR00471 Acetate kinase family signature 344 357 4.7E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 Gene3D G3DSA:3.30.420.40 368 573 4.8E-71 T 29-03-2018 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 SUPERFAMILY SSF53067 329 567 1.01E-80 T 29-03-2018 CB4_RS10735 7dc853224a8dab1271ffdab1ee267724 573 Pfam PF00871 Acetokinase family 241 561 8.2E-121 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 SUPERFAMILY SSF46689 463 510 2.55E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 Gene3D G3DSA:3.30.450.20 51 186 1.3E-19 T 29-03-2018 CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 292 307 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 SUPERFAMILY SSF52540 208 448 6.26E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 SMART SM00091 65 133 5.9E-4 T 29-03-2018 IPR000014 PAS domain CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 Gene3D G3DSA:1.10.8.60 378 470 2.3E-18 T 29-03-2018 CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 SMART SM00382 225 369 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 Pfam PF13426 PAS domain 78 172 1.7E-10 T 29-03-2018 IPR000014 PAS domain CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 Pfam PF00158 Sigma-54 interaction domain 207 373 2.4E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 229 242 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 Gene3D G3DSA:1.10.10.60 471 511 6.2E-5 T 29-03-2018 CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 SUPERFAMILY SSF55785 51 165 2.09E-16 T 29-03-2018 IPR000014 PAS domain CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 67 180 3.0E-12 T 29-03-2018 IPR000014 PAS domain CB4_RS19385 2da67824462455facd5d95776f6f0d66 514 Gene3D G3DSA:3.40.50.300 187 377 8.9E-30 T 29-03-2018 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 PRINTS PR00690 Adhesin family signature 53 66 4.9E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 PRINTS PR00690 Adhesin family signature 196 217 4.9E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 PRINTS PR00690 Adhesin family signature 22 40 4.9E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 PRINTS PR00690 Adhesin family signature 249 267 4.9E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 Gene3D G3DSA:3.40.50.1980 22 190 1.8E-61 T 29-03-2018 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 Gene3D G3DSA:3.40.50.1980 191 311 3.0E-35 T 29-03-2018 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 Pfam PF01297 Zinc-uptake complex component A periplasmic 25 308 2.9E-83 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 PRINTS PR00691 Adhesin B signature 245 262 9.0E-12 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 PRINTS PR00691 Adhesin B signature 22 43 9.0E-12 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 PRINTS PR00691 Adhesin B signature 47 65 9.0E-12 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 PRINTS PR00691 Adhesin B signature 289 307 9.0E-12 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 PRINTS PR00691 Adhesin B signature 66 85 9.0E-12 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CB4_RS00180 544331fa7ea6f459a5ec6474a1fe4668 313 SUPERFAMILY SSF53807 2 310 3.43E-90 T 29-03-2018 CB4_RS04250 757a069db2c55d8edaa781312a910659 494 Pfam PF07690 Major Facilitator Superfamily 11 399 3.6E-50 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS04250 757a069db2c55d8edaa781312a910659 494 Gene3D G3DSA:1.20.1250.20 1 193 2.4E-39 T 29-03-2018 CB4_RS04250 757a069db2c55d8edaa781312a910659 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 129 153 8.9E-8 T 29-03-2018 CB4_RS04250 757a069db2c55d8edaa781312a910659 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 99 119 8.9E-8 T 29-03-2018 CB4_RS04250 757a069db2c55d8edaa781312a910659 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 9 33 8.9E-8 T 29-03-2018 CB4_RS04250 757a069db2c55d8edaa781312a910659 494 PRINTS PR01036 Tetracycline resistance protein TetB signature 392 411 8.9E-8 T 29-03-2018 CB4_RS04250 757a069db2c55d8edaa781312a910659 494 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 6 412 4.1E-77 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CB4_RS04250 757a069db2c55d8edaa781312a910659 494 Gene3D G3DSA:1.20.1250.20 243 486 7.4E-31 T 29-03-2018 CB4_RS04250 757a069db2c55d8edaa781312a910659 494 SUPERFAMILY SSF103473 241 411 6.93E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS04250 757a069db2c55d8edaa781312a910659 494 SUPERFAMILY SSF103473 453 482 6.93E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS04250 757a069db2c55d8edaa781312a910659 494 SUPERFAMILY SSF103473 3 194 6.93E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS19205 3fc01d0e794222504056f861f605957f 225 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 178 6.6E-15 T 29-03-2018 CB4_RS19205 3fc01d0e794222504056f861f605957f 225 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 4 187 5.1E-40 T 29-03-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 CB4_RS19205 3fc01d0e794222504056f861f605957f 225 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 179 5.3E-24 T 29-03-2018 CB4_RS19205 3fc01d0e794222504056f861f605957f 225 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 3 218 40.792 T 29-03-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 CB4_RS19205 3fc01d0e794222504056f861f605957f 225 Gene3D G3DSA:3.40.50.1000 4 225 8.6E-12 T 29-03-2018 IPR023214 HAD-like domain CB4_RS19205 3fc01d0e794222504056f861f605957f 225 SUPERFAMILY SSF56784 1 215 2.99E-45 T 29-03-2018 IPR023214 HAD-like domain CB4_RS02780 e80ba249af57054cffd570c0df567c4f 208 Gene3D G3DSA:1.10.10.60 16 75 4.7E-17 T 29-03-2018 CB4_RS02780 e80ba249af57054cffd570c0df567c4f 208 Gene3D G3DSA:1.10.357.10 76 208 2.7E-12 T 29-03-2018 CB4_RS02780 e80ba249af57054cffd570c0df567c4f 208 SUPERFAMILY SSF46689 18 84 3.04E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS02780 e80ba249af57054cffd570c0df567c4f 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 4.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS02780 e80ba249af57054cffd570c0df567c4f 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 4.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS02780 e80ba249af57054cffd570c0df567c4f 208 SUPERFAMILY SSF48498 95 205 2.52E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS02780 e80ba249af57054cffd570c0df567c4f 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 67 2.9E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS05570 f2c18175ea197acf830a9767b4497840 251 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 61 226 9.6E-21 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS05570 f2c18175ea197acf830a9767b4497840 251 SMART SM00479 64 233 4.6E-26 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS05570 f2c18175ea197acf830a9767b4497840 251 Pfam PF00929 Exonuclease 68 223 1.2E-19 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS05570 f2c18175ea197acf830a9767b4497840 251 Gene3D G3DSA:3.30.420.10 57 239 4.5E-27 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS05570 f2c18175ea197acf830a9767b4497840 251 SUPERFAMILY SSF53098 57 237 2.1E-38 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 Pfam PF05191 Adenylate kinase, active site lid 127 162 1.1E-17 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 PRINTS PR00094 Adenylate kinase signature 81 97 6.9E-31 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 PRINTS PR00094 Adenylate kinase signature 32 46 6.9E-31 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 PRINTS PR00094 Adenylate kinase signature 160 175 6.9E-31 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 PRINTS PR00094 Adenylate kinase signature 4 17 6.9E-31 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 PRINTS PR00094 Adenylate kinase signature 177 191 6.9E-31 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 Gene3D G3DSA:3.40.50.300 1 217 5.7E-64 T 29-03-2018 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 Hamap MF_00235 Adenylate kinase [adk]. 1 213 52.929 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 SUPERFAMILY SSF52540 1 212 1.52E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 Pfam PF00406 Adenylate kinase 5 190 3.5E-58 T 29-03-2018 CB4_RS00850 75c723695f1d6ea3a606481c42cc1836 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 1.6E-78 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CB4_RS10850 9b413821665bfb0b059ff676ba8b455b 182 Pfam PF05573 NosL 44 166 2.2E-11 T 29-03-2018 IPR008719 Nitrous oxide reductase accessory protein NosL CB4_RS10850 9b413821665bfb0b059ff676ba8b455b 182 SUPERFAMILY SSF160387 73 174 5.75E-16 T 29-03-2018 CB4_RS06050 f1a2ef7c316fd47444fc8492f1782301 446 Gene3D G3DSA:1.10.3710.10 356 446 6.3E-31 T 29-03-2018 CB4_RS06050 f1a2ef7c316fd47444fc8492f1782301 446 Pfam PF12002 MgsA AAA+ ATPase C terminal 275 439 9.0E-75 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CB4_RS06050 f1a2ef7c316fd47444fc8492f1782301 446 SUPERFAMILY SSF52540 18 241 5.02E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS06050 f1a2ef7c316fd47444fc8492f1782301 446 Pfam PF16193 AAA C-terminal domain 196 274 4.1E-27 T 29-03-2018 IPR032423 AAA C-terminal domain CB4_RS06050 f1a2ef7c316fd47444fc8492f1782301 446 Gene3D G3DSA:1.20.272.10 259 353 4.2E-41 T 29-03-2018 CB4_RS06050 f1a2ef7c316fd47444fc8492f1782301 446 SUPERFAMILY SSF48019 260 442 1.7E-77 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CB4_RS06050 f1a2ef7c316fd47444fc8492f1782301 446 Gene3D G3DSA:3.40.50.300 7 160 1.1E-30 T 29-03-2018 CB4_RS06050 f1a2ef7c316fd47444fc8492f1782301 446 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 21 145 6.5E-16 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CB4_RS06050 f1a2ef7c316fd47444fc8492f1782301 446 Gene3D G3DSA:1.10.8.60 161 250 3.2E-19 T 29-03-2018 CB4_RS06050 f1a2ef7c316fd47444fc8492f1782301 446 SMART SM00382 55 172 2.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS04645 7182be1d2c88bd7f2548c3a796a3f66f 457 Pfam PF01965 DJ-1/PfpI family 61 226 2.9E-13 T 29-03-2018 IPR002818 DJ-1/PfpI CB4_RS04645 7182be1d2c88bd7f2548c3a796a3f66f 457 Gene3D G3DSA:3.40.50.880 54 254 4.9E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS04645 7182be1d2c88bd7f2548c3a796a3f66f 457 SUPERFAMILY SSF52317 61 245 3.08E-34 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS04645 7182be1d2c88bd7f2548c3a796a3f66f 457 Gene3D G3DSA:3.40.50.880 276 395 0.0037 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS03065 75bfba0bb05502f7fbe32c9f54810b5c 341 Pfam PF08486 Stage II sporulation protein 68 170 4.8E-24 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CB4_RS03065 75bfba0bb05502f7fbe32c9f54810b5c 341 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 70 335 2.5E-75 T 29-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CB4_RS03065 75bfba0bb05502f7fbe32c9f54810b5c 341 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 3 335 1.8E-114 T 29-03-2018 IPR014225 Sporulation stage II, protein D firmicutes CB4_RS16845 bf8c872c91b8b3b7bf0ec90af39d52ee 167 Gene3D G3DSA:1.20.120.450 1 150 1.4E-20 T 29-03-2018 CB4_RS16845 bf8c872c91b8b3b7bf0ec90af39d52ee 167 Pfam PF05163 DinB family 2 157 1.4E-21 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CB4_RS16845 bf8c872c91b8b3b7bf0ec90af39d52ee 167 SUPERFAMILY SSF109854 4 141 3.05E-23 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 SUPERFAMILY SSF51569 8 296 1.36E-99 T 29-03-2018 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 PIRSF PIRSF001365 5 306 3.2E-93 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 Gene3D G3DSA:3.20.20.70 1 300 9.1E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 8 295 56.538 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 140 171 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 42 63 2.5E-28 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 78 96 2.5E-28 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 110 126 2.5E-28 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 135 152 2.5E-28 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 SMART SM01130 8 297 1.2E-129 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 Pfam PF00701 Dihydrodipicolinate synthetase family 9 293 1.1E-90 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 12 293 3.4E-94 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS17610 0216dd0c8cf0ed8cabb9d7132f4267bc 306 TIGRFAM TIGR02313 HpaI-NOT-DapA: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 9 300 9.9E-146 T 29-03-2018 IPR012691 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase variant GO:0005737|GO:0008840|GO:0019877 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 Gene3D G3DSA:1.25.40.10 290 362 1.9E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 Pfam PF14559 Tetratricopeptide repeat 186 239 4.7E-6 T 29-03-2018 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 Gene3D G3DSA:1.25.40.10 363 426 2.4E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 Gene3D G3DSA:1.25.40.10 248 289 0.12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 Gene3D G3DSA:1.25.40.10 194 247 9.7E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 Gene3D G3DSA:1.25.40.10 427 466 0.38 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 SMART SM00028 412 445 59.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 SMART SM00028 275 308 370.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 SMART SM00028 309 342 5.3 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 SMART SM00028 102 135 100.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 SMART SM00028 173 206 27.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 Pfam PF13432 Tetratricopeptide repeat 282 343 4.6E-6 T 29-03-2018 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 Gene3D G3DSA:1.25.40.10 12 193 1.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 SUPERFAMILY SSF48452 336 438 7.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS14955 be7c4e51b1384cdddcfd5d2bebc09023 469 SUPERFAMILY SSF48452 178 368 1.23E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS11210 627660cfbce3884e1d2285c4bc365468 385 Gene3D G3DSA:3.40.50.2000 196 365 2.0E-41 T 29-03-2018 CB4_RS11210 627660cfbce3884e1d2285c4bc365468 385 SUPERFAMILY SSF53756 3 380 4.32E-72 T 29-03-2018 CB4_RS11210 627660cfbce3884e1d2285c4bc365468 385 Pfam PF00534 Glycosyl transferases group 1 207 359 5.0E-38 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CB4_RS11210 627660cfbce3884e1d2285c4bc365468 385 Pfam PF13439 Glycosyltransferase Family 4 13 180 4.9E-18 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CB4_RS11210 627660cfbce3884e1d2285c4bc365468 385 Gene3D G3DSA:3.40.50.2000 1 195 1.7E-12 T 29-03-2018 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 SUPERFAMILY SSF54814 181 298 1.5E-40 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 Hamap MF_00367 GTPase Era [era]. 6 298 39.386 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 8.6E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 78 96 8.6E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 Gene3D G3DSA:3.30.300.20 199 301 6.8E-43 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 Pfam PF07650 KH domain 208 287 4.9E-21 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 Gene3D G3DSA:3.40.50.300 4 24 0.01 T 29-03-2018 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 281 2.1E-101 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 Pfam PF01926 50S ribosome-binding GTPase 11 125 6.7E-26 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 Gene3D G3DSA:3.40.50.300 25 198 1.2E-37 T 29-03-2018 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 167 3.6E-32 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS07115 229ff1257498aa665d7c471d27c8b79a 303 SUPERFAMILY SSF52540 11 206 2.5E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 Gene3D G3DSA:3.30.479.20 57 158 3.6E-27 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 Pfam PF00889 Elongation factor TS 70 274 5.6E-76 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 Gene3D G3DSA:1.10.8.10 1 55 1.4E-25 T 29-03-2018 CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 1.5E-111 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 80.856 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 Gene3D G3DSA:3.30.479.20 159 290 2.0E-50 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 SUPERFAMILY SSF54713 55 146 5.63E-22 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 SUPERFAMILY SSF46934 3 54 2.84E-21 T 29-03-2018 IPR009060 UBA-like GO:0005515 CB4_RS09265 b0a32ff7399c68c76aec868a84414a4c 294 SUPERFAMILY SSF54713 152 293 2.09E-53 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 ProSitePatterns PS00211 ABC transporters family signature. 829 843 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 SUPERFAMILY SSF52540 431 570 5.17E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 SUPERFAMILY SSF52540 8 206 5.17E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 Gene3D G3DSA:1.10.8.280 284 406 2.9E-40 T 29-03-2018 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 Gene3D G3DSA:3.40.50.300 618 951 2.1E-57 T 29-03-2018 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 Gene3D G3DSA:3.40.50.300 426 617 6.5E-24 T 29-03-2018 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 Pfam PF00005 ABC transporter 623 859 8.8E-10 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 939 23.516 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 Gene3D G3DSA:3.40.50.300 4 35 0.015 T 29-03-2018 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 923 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 Gene3D G3DSA:3.40.50.300 36 118 2.1E-8 T 29-03-2018 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 SMART SM00382 25 565 16.0 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 SMART SM00382 632 907 1.5E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 Gene3D G3DSA:3.30.190.20 129 247 5.8E-47 T 29-03-2018 CB4_RS03635 a6284dc41f454caf2707fc04faa95e72 953 SUPERFAMILY SSF52540 613 909 1.01E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS06280 c2330aa60205eb58b61c7369b27817c5 282 SUPERFAMILY SSF51735 25 258 1.73E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS06280 c2330aa60205eb58b61c7369b27817c5 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 198 8.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS06280 c2330aa60205eb58b61c7369b27817c5 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 8.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS06280 c2330aa60205eb58b61c7369b27817c5 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 115 8.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS06280 c2330aa60205eb58b61c7369b27817c5 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 30 47 8.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS06280 c2330aa60205eb58b61c7369b27817c5 282 Gene3D G3DSA:3.40.50.720 22 255 1.6E-43 T 29-03-2018 CB4_RS06280 c2330aa60205eb58b61c7369b27817c5 282 Pfam PF00106 short chain dehydrogenase 29 218 4.0E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS06280 c2330aa60205eb58b61c7369b27817c5 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 104 115 4.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS06280 c2330aa60205eb58b61c7369b27817c5 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 166 4.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS06280 c2330aa60205eb58b61c7369b27817c5 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 179 198 4.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS16935 7df3d51f3d54c9d2ae9669954b6bde04 321 Pfam PF00395 S-layer homology domain 166 210 3.9E-5 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS16935 7df3d51f3d54c9d2ae9669954b6bde04 321 Pfam PF00395 S-layer homology domain 36 76 1.0E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS05635 11c4f4bd5d98175eec222eaaef97e095 211 SUPERFAMILY SSF52540 1 192 3.94E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05635 11c4f4bd5d98175eec222eaaef97e095 211 Pfam PF01926 50S ribosome-binding GTPase 26 143 2.7E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS05635 11c4f4bd5d98175eec222eaaef97e095 211 Gene3D G3DSA:3.40.50.300 10 72 2.2E-12 T 29-03-2018 CB4_RS05635 11c4f4bd5d98175eec222eaaef97e095 211 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.923 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CB4_RS05635 11c4f4bd5d98175eec222eaaef97e095 211 Gene3D G3DSA:3.40.50.300 73 211 1.9E-16 T 29-03-2018 CB4_RS05635 11c4f4bd5d98175eec222eaaef97e095 211 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 6 189 2.3E-73 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CB4_RS03220 702e01c8167875fb37b507fce70b46b0 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 177 7.0E-81 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CB4_RS03220 702e01c8167875fb37b507fce70b46b0 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 178 1.1E-69 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CB4_RS03220 702e01c8167875fb37b507fce70b46b0 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 7.3E-73 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CB4_RS03220 702e01c8167875fb37b507fce70b46b0 182 SUPERFAMILY SSF51182 1 178 1.48E-75 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS03220 702e01c8167875fb37b507fce70b46b0 182 Gene3D G3DSA:2.60.120.10 1 182 5.4E-74 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS04460 865f64598ab16be1e99c0a044591e95e 179 Gene3D G3DSA:3.40.30.10 3 155 1.3E-39 T 29-03-2018 CB4_RS04460 865f64598ab16be1e99c0a044591e95e 179 SUPERFAMILY SSF52833 5 177 1.65E-59 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS04460 865f64598ab16be1e99c0a044591e95e 179 Pfam PF00578 AhpC/TSA family 6 140 3.4E-40 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS04460 865f64598ab16be1e99c0a044591e95e 179 PIRSF PIRSF000239 1 179 3.7E-58 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS04460 865f64598ab16be1e99c0a044591e95e 179 Gene3D G3DSA:3.30.1020.10 156 179 1.7E-5 T 29-03-2018 CB4_RS02860 60574227cdf3a71c5865e14043da8d64 357 SUPERFAMILY SSF75620 8 351 3.79E-135 T 29-03-2018 CB4_RS02860 60574227cdf3a71c5865e14043da8d64 357 Pfam PF00472 RF-1 domain 210 319 1.2E-40 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CB4_RS02860 60574227cdf3a71c5865e14043da8d64 357 Gene3D G3DSA:1.20.58.410 1 94 2.9E-19 T 29-03-2018 CB4_RS02860 60574227cdf3a71c5865e14043da8d64 357 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 352 4.1E-167 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CB4_RS02860 60574227cdf3a71c5865e14043da8d64 357 SMART SM00937 63 177 3.1E-62 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CB4_RS02860 60574227cdf3a71c5865e14043da8d64 357 Gene3D G3DSA:3.30.160.20 207 289 7.9E-31 T 29-03-2018 CB4_RS02860 60574227cdf3a71c5865e14043da8d64 357 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.373 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CB4_RS02860 60574227cdf3a71c5865e14043da8d64 357 Pfam PF03462 PCRF domain 9 202 4.7E-72 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 SUPERFAMILY SSF88697 280 369 2.49E-15 T 29-03-2018 IPR015947 PUA-like domain CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 TIGRFAM TIGR01027 proB: glutamate 5-kinase 8 368 9.3E-136 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 PRINTS PR00474 Glutamate 5-kinase family signature 78 106 4.3E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 PRINTS PR00474 Glutamate 5-kinase family signature 44 58 4.3E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 PRINTS PR00474 Glutamate 5-kinase family signature 211 231 4.3E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 PRINTS PR00474 Glutamate 5-kinase family signature 118 139 4.3E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 PRINTS PR00474 Glutamate 5-kinase family signature 150 177 4.3E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 Gene3D G3DSA:3.40.1160.10 1 266 1.7E-64 T 29-03-2018 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 SMART SM00359 280 363 7.1E-12 T 29-03-2018 IPR002478 PUA domain GO:0003723 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 ProSitePatterns PS00902 Glutamate 5-kinase signature. 209 226 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 SUPERFAMILY SSF53633 8 259 4.97E-71 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 PIRSF PIRSF000729 2 372 4.4E-137 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 Pfam PF00696 Amino acid kinase family 7 235 1.4E-46 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 Hamap MF_00456 Glutamate 5-kinase [proB]. 7 263 37.312 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 Pfam PF01472 PUA domain 280 346 5.1E-17 T 29-03-2018 IPR002478 PUA domain GO:0003723 CB4_RS04400 adc8ccb20125a7ce8a6857adb185f5e8 385 Gene3D G3DSA:2.30.130.10 278 369 5.3E-20 T 29-03-2018 IPR002478 PUA domain GO:0003723 CB4_RS15715 7bb639f15da15ee8724bb98f2075dcba 241 SMART SM00382 26 207 1.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS15715 7bb639f15da15ee8724bb98f2075dcba 241 Pfam PF00005 ABC transporter 18 148 6.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS15715 7bb639f15da15ee8724bb98f2075dcba 241 SUPERFAMILY SSF52540 2 200 5.44E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15715 7bb639f15da15ee8724bb98f2075dcba 241 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS15715 7bb639f15da15ee8724bb98f2075dcba 241 Gene3D G3DSA:3.40.50.300 1 240 2.7E-52 T 29-03-2018 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 8 138 1.7E-28 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 143 415 5.7E-23 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 347 2.4E-53 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 9 419 2.8E-184 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 Gene3D G3DSA:3.40.50.1480 1 140 6.3E-45 T 29-03-2018 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 SUPERFAMILY SSF52283 5 187 1.08E-91 T 29-03-2018 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 SUPERFAMILY SSF52283 350 418 1.08E-91 T 29-03-2018 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 SMART SM00997 188 349 3.1E-105 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 420 45.872 T 29-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 Gene3D G3DSA:3.40.50.1480 207 402 9.3E-62 T 29-03-2018 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 Gene3D G3DSA:3.40.50.1480 141 206 4.9E-9 T 29-03-2018 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 SMART SM00996 6 418 1.1E-125 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 PIRSF PIRSF001109 1 420 1.2E-177 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CB4_RS08210 9e3f541ad701b907bd9deab083f3593b 420 SUPERFAMILY SSF51735 188 350 1.76E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS06010 2aa2f800a9130e619deaaf248080be15 147 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 2.7E-60 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CB4_RS06010 2aa2f800a9130e619deaaf248080be15 147 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 8.0E-62 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CB4_RS06010 2aa2f800a9130e619deaaf248080be15 147 Gene3D G3DSA:3.50.80.10 1 145 1.1E-61 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CB4_RS06010 2aa2f800a9130e619deaaf248080be15 147 SUPERFAMILY SSF69500 1 144 2.22E-59 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CB4_RS06010 2aa2f800a9130e619deaaf248080be15 147 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.769 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CB4_RS17745 7dc4f97409a981ee3de957b114ef7b57 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 83 5.0E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS17745 7dc4f97409a981ee3de957b114ef7b57 228 Gene3D G3DSA:1.10.10.60 32 95 6.4E-17 T 29-03-2018 CB4_RS17745 7dc4f97409a981ee3de957b114ef7b57 228 SUPERFAMILY SSF48498 113 227 1.34E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS17745 7dc4f97409a981ee3de957b114ef7b57 228 SUPERFAMILY SSF46689 31 92 7.77E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS17745 7dc4f97409a981ee3de957b114ef7b57 228 Gene3D G3DSA:1.10.357.10 96 228 1.9E-16 T 29-03-2018 CB4_RS17745 7dc4f97409a981ee3de957b114ef7b57 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 1.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS17745 7dc4f97409a981ee3de957b114ef7b57 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 1.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS17745 7dc4f97409a981ee3de957b114ef7b57 228 ProSitePatterns PS01081 TetR-type HTH domain signature. 50 81 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CB4_RS18505 c254c91b9a912899f4532f513fa511bb 224 Pfam PF02390 Putative methyltransferase 38 208 5.0E-46 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CB4_RS18505 c254c91b9a912899f4532f513fa511bb 224 Gene3D G3DSA:3.40.50.150 1 212 1.0E-28 T 29-03-2018 CB4_RS18505 c254c91b9a912899f4532f513fa511bb 224 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 213 29.162 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CB4_RS18505 c254c91b9a912899f4532f513fa511bb 224 SUPERFAMILY SSF53335 31 210 1.29E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS18505 c254c91b9a912899f4532f513fa511bb 224 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 27 210 2.1E-59 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CB4_RS07960 3361efec0fd5c3f0ba613804538db7bb 324 Gene3D G3DSA:3.30.420.40 145 291 4.6E-17 T 29-03-2018 CB4_RS07960 3361efec0fd5c3f0ba613804538db7bb 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 264 273 2.6E-13 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS07960 3361efec0fd5c3f0ba613804538db7bb 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 160 181 2.6E-13 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS07960 3361efec0fd5c3f0ba613804538db7bb 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 5 18 2.6E-13 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS07960 3361efec0fd5c3f0ba613804538db7bb 324 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 98 117 2.6E-13 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS07960 3361efec0fd5c3f0ba613804538db7bb 324 SUPERFAMILY SSF53067 4 308 8.82E-23 T 29-03-2018 CB4_RS07960 3361efec0fd5c3f0ba613804538db7bb 324 Gene3D G3DSA:3.30.420.40 2 144 6.4E-15 T 29-03-2018 CB4_RS07960 3361efec0fd5c3f0ba613804538db7bb 324 Pfam PF00814 Glycoprotease family 51 306 4.6E-31 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 371 528 4.0E-38 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 ProSitePatterns PS01176 Initiation factor 2 signature. 820 842 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Gene3D G3DSA:3.40.50.300 364 548 4.9E-40 T 29-03-2018 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Gene3D G3DSA:2.40.30.10 549 669 5.6E-35 T 29-03-2018 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Gene3D G3DSA:3.30.56.50 295 336 2.3E-8 T 29-03-2018 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Gene3D G3DSA:3.30.56.50 4 46 3.4E-9 T 29-03-2018 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 SUPERFAMILY SSF50447 541 624 4.32E-27 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 SUPERFAMILY SSF52540 359 542 1.87E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Pfam PF11987 Translation-initiation factor 2 655 759 6.0E-39 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 287 865 2.9E-277 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Pfam PF00009 Elongation factor Tu GTP binding domain 374 529 1.1E-35 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 867 17.825 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 SUPERFAMILY SSF52156 647 776 7.19E-40 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 294 342 2.3E-11 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 2.7E-11 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 SUPERFAMILY SSF50447 770 865 1.58E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Gene3D G3DSA:2.40.30.10 770 867 1.7E-30 T 29-03-2018 CB4_RS09330 c23d90aa039ebff40142ed8cdffb706b 867 Gene3D G3DSA:3.40.50.10050 670 748 9.5E-29 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 3.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 3.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 Gene3D G3DSA:1.20.120.530 85 219 6.6E-19 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 SMART SM00895 86 209 1.5E-4 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 Gene3D G3DSA:1.10.10.10 1 84 1.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 SUPERFAMILY SSF48008 82 207 9.68E-15 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 47 7.7E-7 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 47 66 7.7E-7 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 SUPERFAMILY SSF46785 6 88 3.01E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 2.0E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 Pfam PF07729 FCD domain 90 204 7.4E-16 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS12660 10e01e1f559848072a20bbe0d3729067 219 SMART SM00345 18 76 9.2E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS07620 d8db2f12369b74140aae5ea7c5b26244 223 Pfam PF01184 GPR1/FUN34/yaaH family 12 195 2.8E-18 T 29-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 CB4_RS12880 720fc28dc05e5b6a63447f84be87c785 128 Gene3D G3DSA:1.10.1660.10 57 128 2.3E-13 T 29-03-2018 CB4_RS12880 720fc28dc05e5b6a63447f84be87c785 128 Gene3D G3DSA:1.10.1660.10 1 56 7.0E-23 T 29-03-2018 CB4_RS12880 720fc28dc05e5b6a63447f84be87c785 128 SUPERFAMILY SSF46955 3 115 8.79E-30 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS12880 720fc28dc05e5b6a63447f84be87c785 128 SMART SM00422 2 70 2.1E-21 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS12880 720fc28dc05e5b6a63447f84be87c785 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 3.6E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS12880 720fc28dc05e5b6a63447f84be87c785 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 3.6E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS12880 720fc28dc05e5b6a63447f84be87c785 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.6E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS12880 720fc28dc05e5b6a63447f84be87c785 128 Pfam PF13411 MerR HTH family regulatory protein 3 67 1.2E-21 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS14985 aa81786f7d75452dda4a207c6f337e0a 380 Gene3D G3DSA:3.40.50.2000 186 351 2.0E-40 T 29-03-2018 CB4_RS14985 aa81786f7d75452dda4a207c6f337e0a 380 Gene3D G3DSA:3.40.50.2000 1 185 8.2E-16 T 29-03-2018 CB4_RS14985 aa81786f7d75452dda4a207c6f337e0a 380 Pfam PF00534 Glycosyl transferases group 1 191 346 1.6E-36 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CB4_RS14985 aa81786f7d75452dda4a207c6f337e0a 380 SUPERFAMILY SSF53756 6 372 2.2E-83 T 29-03-2018 CB4_RS14985 aa81786f7d75452dda4a207c6f337e0a 380 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 1 370 2.5E-164 T 29-03-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 CB4_RS14985 aa81786f7d75452dda4a207c6f337e0a 380 Pfam PF13439 Glycosyltransferase Family 4 11 175 6.4E-24 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 SMART SM00740 589 646 0.48 T 29-03-2018 IPR005543 PASTA domain CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 SMART SM00740 648 708 7.1E-10 T 29-03-2018 IPR005543 PASTA domain CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 Gene3D G3DSA:3.90.1310.10 23 226 2.4E-40 T 29-03-2018 CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 SUPERFAMILY SSF54184 652 706 2.62E-9 T 29-03-2018 CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 SUPERFAMILY SSF54184 592 648 2.22E-8 T 29-03-2018 CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 SUPERFAMILY SSF56601 182 589 2.15E-98 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 Gene3D G3DSA:3.40.710.10 227 577 6.7E-95 T 29-03-2018 CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 Pfam PF03793 PASTA domain 653 706 1.7E-9 T 29-03-2018 IPR005543 PASTA domain CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 SUPERFAMILY SSF56519 53 229 1.44E-40 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 Pfam PF03717 Penicillin-binding Protein dimerisation domain 54 211 8.3E-18 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CB4_RS08225 c41ae8f929372fcbbd36e0433c3b50e4 732 Pfam PF00905 Penicillin binding protein transpeptidase domain 256 569 2.3E-85 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CB4_RS10935 67c467f0a159c41bb2dc769f2ee93fb4 475 PRINTS PR00175 Sodium/alanine symporter signature 300 318 1.0E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS10935 67c467f0a159c41bb2dc769f2ee93fb4 475 PRINTS PR00175 Sodium/alanine symporter signature 345 367 1.0E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS10935 67c467f0a159c41bb2dc769f2ee93fb4 475 PRINTS PR00175 Sodium/alanine symporter signature 181 199 1.0E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS10935 67c467f0a159c41bb2dc769f2ee93fb4 475 PRINTS PR00175 Sodium/alanine symporter signature 405 425 1.0E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS10935 67c467f0a159c41bb2dc769f2ee93fb4 475 PRINTS PR00175 Sodium/alanine symporter signature 209 228 1.0E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS10935 67c467f0a159c41bb2dc769f2ee93fb4 475 PRINTS PR00175 Sodium/alanine symporter signature 91 113 1.0E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS10935 67c467f0a159c41bb2dc769f2ee93fb4 475 Pfam PF01235 Sodium:alanine symporter family 52 448 9.3E-158 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS10935 67c467f0a159c41bb2dc769f2ee93fb4 475 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 436 3.4E-151 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS19550 cfcd0e6c916e08258b5e519bd67601f6 401 SMART SM00530 11 66 4.4E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS19550 cfcd0e6c916e08258b5e519bd67601f6 401 SUPERFAMILY SSF47413 4 70 1.55E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS19550 cfcd0e6c916e08258b5e519bd67601f6 401 Pfam PF06114 IrrE N-terminal-like domain 189 297 2.0E-14 T 29-03-2018 IPR010359 IrrE N-terminal-like domain CB4_RS19550 cfcd0e6c916e08258b5e519bd67601f6 401 Gene3D G3DSA:1.10.3100.10 1 156 2.3E-17 T 29-03-2018 IPR027910 YdiL-like domain CB4_RS19550 cfcd0e6c916e08258b5e519bd67601f6 401 Pfam PF01381 Helix-turn-helix 13 65 6.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS04445 e3d65ccba2b8e85e4b166b9ef43119ac 257 SUPERFAMILY SSF52540 4 228 4.02E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS04445 e3d65ccba2b8e85e4b166b9ef43119ac 257 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS04445 e3d65ccba2b8e85e4b166b9ef43119ac 257 Gene3D G3DSA:3.40.50.300 1 232 2.7E-61 T 29-03-2018 CB4_RS04445 e3d65ccba2b8e85e4b166b9ef43119ac 257 Pfam PF00005 ABC transporter 17 165 6.5E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS04445 e3d65ccba2b8e85e4b166b9ef43119ac 257 SMART SM00382 26 214 3.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 Gene3D G3DSA:2.40.50.140 634 716 8.2E-23 T 29-03-2018 CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 Pfam PF09371 Tex-like protein N-terminal domain 10 192 6.2E-71 T 29-03-2018 IPR018974 Tex-like protein, N-terminal CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 SUPERFAMILY SSF47781 461 549 8.0E-26 T 29-03-2018 IPR010994 RuvA domain 2-like CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 Pfam PF16921 Tex protein YqgF-like domain 318 442 2.2E-56 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 Gene3D G3DSA:1.10.3500.10 351 489 9.3E-42 T 29-03-2018 IPR023323 Tex-like domain CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 Pfam PF12836 Helix-hairpin-helix motif 482 546 4.6E-25 T 29-03-2018 CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 SUPERFAMILY SSF47781 551 626 1.31E-15 T 29-03-2018 IPR010994 RuvA domain 2-like CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 SUPERFAMILY SSF53098 313 460 2.12E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 Pfam PF00575 S1 RNA binding domain 643 713 1.9E-16 T 29-03-2018 IPR003029 S1 domain GO:0003676 CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 SUPERFAMILY SSF158832 6 312 2.09E-113 T 29-03-2018 CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 Gene3D G3DSA:1.10.10.650 3 102 2.4E-34 T 29-03-2018 IPR023319 Tex-like protein, HTH domain CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 Gene3D G3DSA:1.10.3500.10 103 350 3.0E-83 T 29-03-2018 IPR023323 Tex-like domain CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 SMART SM00732 317 415 4.6E-36 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 Gene3D G3DSA:1.10.150.310 490 624 1.6E-43 T 29-03-2018 CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 SMART SM00316 643 714 1.1E-20 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS20525 792c3425f43dcced02cc8f37e5afca7f 717 SUPERFAMILY SSF50249 628 714 1.12E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 Gene3D G3DSA:1.10.730.10 588 812 3.9E-62 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 1.6E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 549 558 1.6E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 220 243 1.6E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 382 397 1.6E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 509 522 1.6E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 620 4.6E-198 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 SUPERFAMILY SSF52374 384 637 2.29E-139 T 29-03-2018 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 SUPERFAMILY SSF52374 13 197 2.29E-139 T 29-03-2018 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 SUPERFAMILY SSF47323 948 1025 3.47E-5 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 Gene3D G3DSA:3.40.50.620 374 587 3.0E-61 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1026 13.843 T 29-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 Gene3D G3DSA:3.90.740.10 211 373 8.6E-64 T 29-03-2018 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 Pfam PF08264 Anticodon-binding domain of tRNA 675 817 5.2E-33 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 SUPERFAMILY SSF47323 647 878 7.48E-53 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 SUPERFAMILY SSF50677 199 384 4.32E-51 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 11 822 7.2E-293 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CB4_RS13740 ba46e12287abddedfbe51fe4ab5335e7 1033 Gene3D G3DSA:3.40.50.620 26 210 3.7E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 Pfam PF07690 Major Facilitator Superfamily 25 418 6.3E-51 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 23 47 4.0E-10 T 29-03-2018 CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 4.0E-10 T 29-03-2018 CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 169 193 4.0E-10 T 29-03-2018 CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 4.0E-10 T 29-03-2018 CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 308 332 4.0E-10 T 29-03-2018 CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 Gene3D G3DSA:1.20.1250.20 15 206 1.5E-36 T 29-03-2018 CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 491 1.8E-115 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 Gene3D G3DSA:1.20.1250.20 265 513 9.8E-26 T 29-03-2018 CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 SUPERFAMILY SSF103473 472 507 2.35E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 SUPERFAMILY SSF103473 255 428 2.35E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS03280 988833570d1bdce9cbcad6f92e7c7b0b 515 SUPERFAMILY SSF103473 17 209 2.35E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS15025 fd664c3edddb728f125488eaee4c07fc 390 Gene3D G3DSA:3.50.50.60 150 349 3.8E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15025 fd664c3edddb728f125488eaee4c07fc 390 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 322 1.3E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15025 fd664c3edddb728f125488eaee4c07fc 390 Gene3D G3DSA:3.50.50.60 4 149 5.3E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15025 fd664c3edddb728f125488eaee4c07fc 390 SUPERFAMILY SSF51905 1 119 3.82E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15025 fd664c3edddb728f125488eaee4c07fc 390 SUPERFAMILY SSF51905 216 336 3.82E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15025 fd664c3edddb728f125488eaee4c07fc 390 SUPERFAMILY SSF51905 157 175 3.82E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15025 fd664c3edddb728f125488eaee4c07fc 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.5E-6 T 29-03-2018 CB4_RS15025 fd664c3edddb728f125488eaee4c07fc 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 2.5E-6 T 29-03-2018 CB4_RS15025 fd664c3edddb728f125488eaee4c07fc 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 2.5E-6 T 29-03-2018 CB4_RS08655 1b92b78825bde98cff5499049b5bdfab 114 Gene3D G3DSA:1.10.10.10 1 110 6.1E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08655 1b92b78825bde98cff5499049b5bdfab 114 SUPERFAMILY SSF88659 1 89 2.06E-27 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08655 1b92b78825bde98cff5499049b5bdfab 114 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 89 3.2E-31 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CB4_RS08655 1b92b78825bde98cff5499049b5bdfab 114 Hamap MF_00245 UPF0122 protein . 2 107 19.037 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 SUPERFAMILY SSF52540 808 857 8.21E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 SMART SM00306 383 480 2.4E-23 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 SUPERFAMILY SSF52540 183 389 1.21E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 Pfam PF14528 LAGLIDADG-like domain 603 680 1.6E-17 T 29-03-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 788 810 9.8E-8 T 29-03-2018 IPR030934 Intein C-terminal splicing region CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 866 1.3E-180 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 SUPERFAMILY SSF51294 384 509 3.34E-40 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 SUPERFAMILY SSF51294 745 809 3.34E-40 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 Pfam PF14890 Intein splicing domain 396 809 8.0E-38 T 29-03-2018 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 Gene3D G3DSA:3.40.50.300 167 389 8.7E-52 T 29-03-2018 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 Pfam PF03796 DnaB-like helicase C terminal domain 185 864 1.8E-111 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 PRINTS PR00379 Intein signature 633 648 2.7E-21 T 29-03-2018 IPR006142 Intein GO:0016539 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 PRINTS PR00379 Intein signature 804 813 2.7E-21 T 29-03-2018 IPR006142 Intein GO:0016539 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 PRINTS PR00379 Intein signature 786 803 2.7E-21 T 29-03-2018 IPR006142 Intein GO:0016539 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 PRINTS PR00379 Intein signature 602 614 2.7E-21 T 29-03-2018 IPR006142 Intein GO:0016539 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 PRINTS PR00379 Intein signature 498 510 2.7E-21 T 29-03-2018 IPR006142 Intein GO:0016539 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 PRINTS PR00379 Intein signature 447 460 2.7E-21 T 29-03-2018 IPR006142 Intein GO:0016539 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 SMART SM00305 770 815 3.6E-14 T 29-03-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 Gene3D G3DSA:3.40.50.300 798 871 1.4E-5 T 29-03-2018 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 385 460 7.4E-11 T 29-03-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 SUPERFAMILY SSF48024 8 119 1.31E-37 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 Gene3D G3DSA:1.10.860.10 5 151 4.2E-47 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 Gene3D G3DSA:2.170.16.10 390 797 1.8E-46 T 29-03-2018 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 1.5E-35 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CB4_RS02030 ea52ef365a68601a64374b42eebc057c 872 SUPERFAMILY SSF55608 588 685 1.08E-14 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CB4_RS17855 728be7e25517c45e0038c16ce2c39546 273 Pfam PF11307 Protein of unknown function (DUF3109) 75 195 1.6E-8 T 29-03-2018 IPR021458 Protein of unknown function DUF3109 CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 SUPERFAMILY SSF56024 292 491 2.06E-49 T 29-03-2018 CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 Gene3D G3DSA:3.30.870.10 121 311 9.3E-34 T 29-03-2018 CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 Pfam PF13396 Phospholipase_D-nuclease N-terminal 38 79 3.7E-10 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 SMART SM00155 240 267 1.2E-6 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 SMART SM00155 417 444 2.3E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 Hamap MF_01916 Cardiolipin synthase. 32 504 42.53 T 29-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 SUPERFAMILY SSF56024 116 334 8.79E-55 T 29-03-2018 CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 Gene3D G3DSA:3.30.870.10 335 499 1.0E-30 T 29-03-2018 CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 31 504 1.0E-169 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 Pfam PF13091 PLD-like domain 158 300 2.3E-15 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CB4_RS04320 b9d92b9ef0556aac1105f44c183236d9 504 Pfam PF13091 PLD-like domain 347 468 1.4E-25 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 SMART SM00851 960 1044 8.5E-8 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Gene3D G3DSA:1.10.1030.10 404 534 7.4E-49 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 543 1.3E-38 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Gene3D G3DSA:3.40.50.1380 944 1069 5.7E-19 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Gene3D G3DSA:3.30.1490.20 661 749 8.0E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 SUPERFAMILY SSF52440 555 672 4.03E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 SUPERFAMILY SSF48108 395 548 6.41E-46 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 SMART SM01096 420 543 1.3E-59 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Gene3D G3DSA:3.40.50.20 5 117 5.5E-39 T 29-03-2018 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 SUPERFAMILY SSF52335 949 1058 1.7E-15 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Gene3D G3DSA:3.40.50.20 535 659 1.2E-59 T 29-03-2018 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 1.5E-82 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 670 874 2.9E-37 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Gene3D G3DSA:3.30.470.20 120 401 2.2E-64 T 29-03-2018 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 SUPERFAMILY SSF56059 670 934 4.6E-82 T 29-03-2018 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 SMART SM01209 676 845 0.0045 T 29-03-2018 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1052 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 SUPERFAMILY SSF52440 1 126 4.32E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Gene3D G3DSA:3.30.470.20 750 934 1.5E-34 T 29-03-2018 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.1E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.1E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.1E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.1E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.1E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.1E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.1E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Pfam PF02142 MGS-like domain 962 1044 1.7E-9 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 706 720 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1065 12.537 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03565 7d8cff152894222b21c7ac0ffab2a1b0 1080 SUPERFAMILY SSF56059 128 399 5.3E-109 T 29-03-2018 CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 SMART SM00419 172 220 2.2E-12 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 Gene3D G3DSA:2.60.120.10 6 148 5.1E-37 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 178 194 4.8E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 194 209 4.8E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 Pfam PF00027 Cyclic nucleotide-binding domain 34 121 1.5E-22 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 Pfam PF13545 Crp-like helix-turn-helix domain 154 226 2.2E-16 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 SUPERFAMILY SSF51206 8 146 4.84E-36 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 SMART SM00100 15 133 3.5E-27 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 Gene3D G3DSA:1.10.10.10 149 229 6.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 SUPERFAMILY SSF46785 150 229 3.85E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18260 c4cf5134c18098c68a2f7c6cc33a520c 231 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 82 100 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CB4_RS00290 de9da5aa611fe61eb164fb5d2df3aa10 479 SUPERFAMILY SSF46689 424 473 2.73E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS00290 de9da5aa611fe61eb164fb5d2df3aa10 479 SMART SM00342 388 471 3.3E-34 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CB4_RS00290 de9da5aa611fe61eb164fb5d2df3aa10 479 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 425 467 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CB4_RS00290 de9da5aa611fe61eb164fb5d2df3aa10 479 SUPERFAMILY SSF46689 371 421 2.85E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS00290 de9da5aa611fe61eb164fb5d2df3aa10 479 Gene3D G3DSA:2.60.120.10 249 427 3.3E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS00290 de9da5aa611fe61eb164fb5d2df3aa10 479 Gene3D G3DSA:1.10.10.60 428 475 6.9E-15 T 29-03-2018 CB4_RS00290 de9da5aa611fe61eb164fb5d2df3aa10 479 Pfam PF12833 Helix-turn-helix domain 395 472 6.9E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CB4_RS00290 de9da5aa611fe61eb164fb5d2df3aa10 479 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 440 455 6.9E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CB4_RS00290 de9da5aa611fe61eb164fb5d2df3aa10 479 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 455 471 6.9E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CB4_RS09500 3dd23ef98981fa7ab65daeb607ca7d7f 112 Gene3D G3DSA:3.60.15.10 1 100 1.9E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS09500 3dd23ef98981fa7ab65daeb607ca7d7f 112 SUPERFAMILY SSF56281 2 110 4.06E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS00915 ea276fc769afc01eb7324307bb161ee2 65 SUPERFAMILY SSF46561 1 63 1.57E-23 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00915 ea276fc769afc01eb7324307bb161ee2 65 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00915 ea276fc769afc01eb7324307bb161ee2 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.115 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00915 ea276fc769afc01eb7324307bb161ee2 65 Pfam PF00831 Ribosomal L29 protein 4 60 2.8E-25 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00915 ea276fc769afc01eb7324307bb161ee2 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 9.6E-23 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00915 ea276fc769afc01eb7324307bb161ee2 65 Gene3D G3DSA:1.10.287.310 1 64 1.7E-24 T 29-03-2018 CB4_RS01780 4fb6ecbfbfcf74b39ee12e199adfe5a8 402 Gene3D G3DSA:3.40.50.150 213 402 4.5E-26 T 29-03-2018 CB4_RS01780 4fb6ecbfbfcf74b39ee12e199adfe5a8 402 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 228 348 3.1E-37 T 29-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CB4_RS01780 4fb6ecbfbfcf74b39ee12e199adfe5a8 402 PIRSF PIRSF036428 1 400 4.2E-119 T 29-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CB4_RS01780 4fb6ecbfbfcf74b39ee12e199adfe5a8 402 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 238 345 2.0E-7 T 29-03-2018 CB4_RS01780 4fb6ecbfbfcf74b39ee12e199adfe5a8 402 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 187 4.3E-16 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01780 4fb6ecbfbfcf74b39ee12e199adfe5a8 402 SUPERFAMILY SSF53790 5 201 2.09E-36 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01780 4fb6ecbfbfcf74b39ee12e199adfe5a8 402 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 7 199 2.2E-57 T 29-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CB4_RS01780 4fb6ecbfbfcf74b39ee12e199adfe5a8 402 Gene3D G3DSA:3.40.1010.10 3 109 4.9E-9 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01780 4fb6ecbfbfcf74b39ee12e199adfe5a8 402 Gene3D G3DSA:3.30.950.10 110 206 1.6E-31 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01780 4fb6ecbfbfcf74b39ee12e199adfe5a8 402 SUPERFAMILY SSF53335 188 364 1.3E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS09985 7a5c4ec3787637d72dbedce1589d43e3 226 SMART SM00862 152 223 2.4E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS09985 7a5c4ec3787637d72dbedce1589d43e3 226 Gene3D G3DSA:1.10.10.10 125 225 1.3E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09985 7a5c4ec3787637d72dbedce1589d43e3 226 SUPERFAMILY SSF46894 130 224 1.96E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS09985 7a5c4ec3787637d72dbedce1589d43e3 226 Gene3D G3DSA:3.40.50.2300 1 124 4.7E-30 T 29-03-2018 CB4_RS09985 7a5c4ec3787637d72dbedce1589d43e3 226 Pfam PF00072 Response regulator receiver domain 5 113 5.3E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS09985 7a5c4ec3787637d72dbedce1589d43e3 226 SMART SM00448 3 113 6.9E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS09985 7a5c4ec3787637d72dbedce1589d43e3 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 223 1.1E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS09985 7a5c4ec3787637d72dbedce1589d43e3 226 SUPERFAMILY SSF52172 2 130 6.55E-35 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS09430 d8c35ccf9116a297016d7689de286874 303 SUPERFAMILY SSF51735 149 248 7.65E-19 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS09430 d8c35ccf9116a297016d7689de286874 303 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 5 288 9.5E-119 T 29-03-2018 IPR014215 Dipicolinic acid synthetase subunit A CB4_RS09430 d8c35ccf9116a297016d7689de286874 303 Gene3D G3DSA:3.40.50.720 1 137 2.0E-4 T 29-03-2018 CB4_RS09430 d8c35ccf9116a297016d7689de286874 303 Gene3D G3DSA:3.40.50.720 138 272 2.0E-22 T 29-03-2018 CB4_RS09430 d8c35ccf9116a297016d7689de286874 303 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 7 123 1.0E-27 T 29-03-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal CB4_RS09430 d8c35ccf9116a297016d7689de286874 303 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 152 288 6.8E-8 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CB4_RS16955 9a8136ba95d0054da153b6c84d83bc11 530 Pfam PF00501 AMP-binding enzyme 20 425 2.5E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS16955 9a8136ba95d0054da153b6c84d83bc11 530 Pfam PF13193 AMP-binding enzyme C-terminal domain 434 512 3.1E-24 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS16955 9a8136ba95d0054da153b6c84d83bc11 530 Gene3D G3DSA:3.40.50.980 10 182 3.1E-36 T 29-03-2018 CB4_RS16955 9a8136ba95d0054da153b6c84d83bc11 530 Gene3D G3DSA:3.40.50.980 183 330 2.2E-37 T 29-03-2018 CB4_RS16955 9a8136ba95d0054da153b6c84d83bc11 530 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS16955 9a8136ba95d0054da153b6c84d83bc11 530 Gene3D G3DSA:3.30.300.30 420 530 1.5E-29 T 29-03-2018 CB4_RS16955 9a8136ba95d0054da153b6c84d83bc11 530 Gene3D G3DSA:2.30.38.10 331 418 8.2E-26 T 29-03-2018 CB4_RS16955 9a8136ba95d0054da153b6c84d83bc11 530 SUPERFAMILY SSF56801 19 523 1.13E-151 T 29-03-2018 CB4_RS00890 4e33c75169ddb64221f87354f62ef556 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00890 4e33c75169ddb64221f87354f62ef556 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 3.4E-24 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00890 4e33c75169ddb64221f87354f62ef556 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.148 T 29-03-2018 IPR023053 Ribosomal protein S14, type Z CB4_RS00890 4e33c75169ddb64221f87354f62ef556 61 SUPERFAMILY SSF57716 3 61 3.49E-21 T 29-03-2018 CB4_RS00890 4e33c75169ddb64221f87354f62ef556 61 Gene3D G3DSA:4.10.830.10 1 61 4.5E-21 T 29-03-2018 CB4_RS13040 868a1e9a82b4700f304395ed981862ac 146 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 16 145 1.8E-41 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 CB4_RS13040 868a1e9a82b4700f304395ed981862ac 146 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 146 28.682 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 CB4_RS01355 4b96197ebbb0330537e9a76e046488f2 280 SUPERFAMILY SSF56752 1 277 4.71E-75 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CB4_RS01355 4b96197ebbb0330537e9a76e046488f2 280 Gene3D G3DSA:3.30.470.10 1 132 1.1E-29 T 29-03-2018 CB4_RS01355 4b96197ebbb0330537e9a76e046488f2 280 Gene3D G3DSA:3.20.10.10 133 280 1.4E-37 T 29-03-2018 CB4_RS01355 4b96197ebbb0330537e9a76e046488f2 280 Pfam PF01063 Amino-transferase class IV 29 255 2.4E-47 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CB4_RS11145 1c425f2f5158a4cc2ac77695a9ee6255 161 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 32 3.6E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS11145 1c425f2f5158a4cc2ac77695a9ee6255 161 Pfam PF08334 Type II secretion system (T2SS), protein G 36 133 1.4E-8 T 29-03-2018 IPR013545 Type II secretion system protein G CB4_RS11145 1c425f2f5158a4cc2ac77695a9ee6255 161 Gene3D G3DSA:3.30.700.10 13 159 2.0E-17 T 29-03-2018 CB4_RS11145 1c425f2f5158a4cc2ac77695a9ee6255 161 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 31 2.0E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS11145 1c425f2f5158a4cc2ac77695a9ee6255 161 SUPERFAMILY SSF54523 12 148 1.31E-18 T 29-03-2018 CB4_RS11145 1c425f2f5158a4cc2ac77695a9ee6255 161 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS11145 1c425f2f5158a4cc2ac77695a9ee6255 161 PRINTS PR00813 Bacterial general secretion pathway protein G signature 11 36 2.2E-5 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CB4_RS11145 1c425f2f5158a4cc2ac77695a9ee6255 161 PRINTS PR00813 Bacterial general secretion pathway protein G signature 47 65 2.2E-5 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 Pfam PF00067 Cytochrome P450 12 428 6.4E-86 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 Pfam PF00175 Oxidoreductase NAD-binding domain 912 1020 2.1E-18 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PIRSF PIRSF000209 1 1060 0.0 T 29-03-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 Gene3D G3DSA:1.10.630.10 4 459 1.7E-112 T 29-03-2018 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00369 Flavodoxin signature 571 581 2.9E-7 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00369 Flavodoxin signature 493 506 2.9E-7 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00369 Flavodoxin signature 596 615 2.9E-7 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 Gene3D G3DSA:2.40.30.10 661 892 9.9E-53 T 29-03-2018 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 Pfam PF00667 FAD binding domain 673 879 6.4E-39 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 Gene3D G3DSA:3.40.50.360 460 653 3.6E-42 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 Gene3D G3DSA:3.40.50.80 897 1056 3.5E-35 T 29-03-2018 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 SUPERFAMILY SSF63380 672 895 2.84E-64 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 911 930 6.4E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 952 963 6.4E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 874 883 6.4E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 940 949 6.4E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 983 999 6.4E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1006 1014 6.4E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 705 715 6.4E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 839 846 6.4E-31 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 SUPERFAMILY SSF48264 7 454 1.14E-107 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 Pfam PF00258 Flavodoxin 494 626 1.9E-25 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 SUPERFAMILY SSF52218 488 643 4.4E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS10670 13f31b66066fa507072b022c1a098a1a 1060 SUPERFAMILY SSF52343 899 1057 9.56E-46 T 29-03-2018 CB4_RS00480 d7ef461e14e87fdc08ac9dac4bff88d8 519 Gene3D G3DSA:1.10.275.10 13 205 8.0E-63 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CB4_RS00480 d7ef461e14e87fdc08ac9dac4bff88d8 519 Pfam PF00221 Aromatic amino acid lyase 23 479 5.5E-172 T 29-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CB4_RS00480 d7ef461e14e87fdc08ac9dac4bff88d8 519 Gene3D G3DSA:1.20.200.10 207 518 1.5E-110 T 29-03-2018 CB4_RS00480 d7ef461e14e87fdc08ac9dac4bff88d8 519 SUPERFAMILY SSF48557 14 510 3.37E-170 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CB4_RS00480 d7ef461e14e87fdc08ac9dac4bff88d8 519 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 15 512 1.3E-174 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS13135 c0574022ee29e648ad55914114ac68b3 246 Gene3D G3DSA:1.10.3290.10 2 246 3.2E-71 T 29-03-2018 IPR003812 Fido domain CB4_RS13135 c0574022ee29e648ad55914114ac68b3 246 SUPERFAMILY SSF140931 68 243 1.57E-43 T 29-03-2018 IPR003812 Fido domain CB4_RS13135 c0574022ee29e648ad55914114ac68b3 246 Pfam PF02661 Fic/DOC family 93 190 6.3E-27 T 29-03-2018 IPR003812 Fido domain CB4_RS03450 cc6bf8ae67f6fa50e24d78c2c5ca2574 131 Pfam PF03646 FlaG protein 38 129 1.4E-15 T 29-03-2018 IPR005186 FlaG protein CB4_RS03450 cc6bf8ae67f6fa50e24d78c2c5ca2574 131 Gene3D G3DSA:3.30.160.170 33 127 1.3E-16 T 29-03-2018 IPR005186 FlaG protein CB4_RS03450 cc6bf8ae67f6fa50e24d78c2c5ca2574 131 SUPERFAMILY SSF160214 39 130 1.12E-18 T 29-03-2018 IPR005186 FlaG protein CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 SUPERFAMILY SSF46609 40 127 3.8E-33 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 45 126 1.0E-28 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 Gene3D G3DSA:1.10.287.990 63 126 2.3E-20 T 29-03-2018 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 135 235 3.6E-39 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 202 209 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 SUPERFAMILY SSF54719 125 239 9.69E-45 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 PIRSF PIRSF000349 16 244 8.5E-91 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 PRINTS PR01703 Manganese superoxide dismutase signature 200 212 1.8E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 PRINTS PR01703 Manganese superoxide dismutase signature 49 60 1.8E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 PRINTS PR01703 Manganese superoxide dismutase signature 109 122 1.8E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 PRINTS PR01703 Manganese superoxide dismutase signature 70 83 1.8E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS05250 9e4fe164a8ebf9f068863c93f660ff72 244 PRINTS PR01703 Manganese superoxide dismutase signature 162 170 1.8E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS06720 d262951660bedae8877db7371f822037 235 Pfam PF08279 HTH domain 172 211 2.2E-6 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CB4_RS06720 d262951660bedae8877db7371f822037 235 Gene3D G3DSA:3.40.50.2300 4 151 1.9E-35 T 29-03-2018 CB4_RS06720 d262951660bedae8877db7371f822037 235 SMART SM00448 5 118 1.2E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS06720 d262951660bedae8877db7371f822037 235 SUPERFAMILY SSF52172 4 134 8.25E-39 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS06720 d262951660bedae8877db7371f822037 235 Pfam PF00072 Response regulator receiver domain 7 117 2.1E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS06720 d262951660bedae8877db7371f822037 235 Gene3D G3DSA:1.10.10.10 168 231 3.1E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS06720 d262951660bedae8877db7371f822037 235 PIRSF PIRSF006171 3 235 1.1E-74 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CB4_RS06720 d262951660bedae8877db7371f822037 235 SUPERFAMILY SSF46785 172 219 3.99E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19865 fe354ff184d1f4490175d20653f05066 345 Gene3D G3DSA:3.40.50.300 136 341 5.3E-11 T 29-03-2018 CB4_RS19865 fe354ff184d1f4490175d20653f05066 345 SUPERFAMILY SSF52540 140 308 2.66E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19865 fe354ff184d1f4490175d20653f05066 345 SMART SM00450 5 131 4.7E-15 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS19865 fe354ff184d1f4490175d20653f05066 345 Gene3D G3DSA:3.40.250.10 1 135 1.1E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS19865 fe354ff184d1f4490175d20653f05066 345 Pfam PF00581 Rhodanese-like domain 9 126 6.3E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS19865 fe354ff184d1f4490175d20653f05066 345 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 20 316 9.8E-95 T 29-03-2018 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 CB4_RS19865 fe354ff184d1f4490175d20653f05066 345 SUPERFAMILY SSF52821 5 131 3.4E-23 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS00600 fc9a9967051c723659d3a6c7236ae7df 596 Pfam PF10592 AIPR protein 267 539 2.7E-42 T 29-03-2018 IPR018891 Abortive bacteriophage infection, resistance CB4_RS07030 8763c0fe3c94de572f2fd1a019685b60 298 Gene3D G3DSA:3.40.50.2300 1 149 2.0E-24 T 29-03-2018 CB4_RS07030 8763c0fe3c94de572f2fd1a019685b60 298 SUPERFAMILY SSF52172 4 140 1.05E-24 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS07030 8763c0fe3c94de572f2fd1a019685b60 298 SMART SM00448 3 116 1.5E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS07030 8763c0fe3c94de572f2fd1a019685b60 298 Pfam PF08664 YcbB domain 160 289 6.1E-45 T 29-03-2018 IPR013972 YcbB domain CB4_RS07030 8763c0fe3c94de572f2fd1a019685b60 298 Pfam PF00072 Response regulator receiver domain 6 116 4.7E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 Pfam PF00117 Glutamine amidotransferase class-I 175 351 1.1E-46 T 29-03-2018 IPR017926 Glutamine amidotransferase CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 8.5E-54 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 Gene3D G3DSA:3.50.30.20 2 142 8.3E-62 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 215 224 3.5E-12 T 29-03-2018 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 328 341 3.5E-12 T 29-03-2018 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 253 3.5E-12 T 29-03-2018 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 173 187 2.8E-36 T 29-03-2018 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 284 295 2.8E-36 T 29-03-2018 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 276 2.8E-36 T 29-03-2018 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 242 258 2.8E-36 T 29-03-2018 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 212 226 2.8E-36 T 29-03-2018 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 354 5.0E-146 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 SUPERFAMILY SSF52021 4 146 4.18E-59 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 SMART SM01097 3 133 2.0E-91 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 357 48.779 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 Gene3D G3DSA:3.40.50.880 143 358 4.3E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 SUPERFAMILY SSF52317 152 354 4.77E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00097 Anthranilate synthase component II signature 242 253 4.9E-7 T 29-03-2018 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00097 Anthranilate synthase component II signature 215 224 4.9E-7 T 29-03-2018 CB4_RS08390 7fe227ec1108f51efa2172c884ee29a0 366 PRINTS PR00097 Anthranilate synthase component II signature 328 341 4.9E-7 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 SUPERFAMILY SSF82866 794 1016 2.09E-50 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 Gene3D G3DSA:1.20.1640.10 809 1028 4.6E-41 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 Gene3D G3DSA:3.30.70.1430 558 658 1.6E-22 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 SUPERFAMILY SSF82693 137 180 9.42E-21 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 SUPERFAMILY SSF82693 266 321 9.42E-21 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 Gene3D G3DSA:3.30.70.1430 40 141 1.5E-28 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 SUPERFAMILY SSF82866 289 488 4.58E-39 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 SUPERFAMILY SSF82693 41 134 2.33E-24 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 SUPERFAMILY SSF82693 557 653 1.94E-15 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 Gene3D G3DSA:3.30.2090.10 709 797 3.3E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 Gene3D G3DSA:1.20.1640.10 265 491 4.4E-40 T 29-03-2018 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 1.9E-43 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 PRINTS PR00702 Acriflavin resistance protein family signature 614 628 1.9E-43 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 1.9E-43 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 1.9E-43 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.9E-43 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.9E-43 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 1.9E-43 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.9E-43 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 1.9E-43 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 SUPERFAMILY SSF82714 710 795 1.31E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 SUPERFAMILY SSF82714 182 263 3.92E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 Gene3D G3DSA:3.30.2090.10 179 264 3.9E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS12935 59f4754695c88c5828ea0bb465103074 1037 Pfam PF00873 AcrB/AcrD/AcrF family 3 1014 3.1E-266 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 Gene3D G3DSA:3.40.50.300 418 592 1.5E-32 T 29-03-2018 CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 8 660 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 SMART SM00487 13 429 3.9E-26 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 SUPERFAMILY SSF52540 7 418 1.14E-135 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 SUPERFAMILY SSF46600 617 661 3.92E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 Gene3D G3DSA:4.10.860.10 599 663 5.3E-15 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 SMART SM00490 463 549 3.1E-21 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 Pfam PF04851 Type III restriction enzyme, res subunit 17 143 2.0E-13 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 Hamap MF_00204 UvrABC system protein B [uvrB]. 7 662 43.844 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 Pfam PF02151 UvrB/uvrC motif 627 661 1.4E-9 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 Gene3D G3DSA:3.40.50.300 12 416 4.9E-30 T 29-03-2018 CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 Pfam PF00271 Helicase conserved C-terminal domain 448 548 1.5E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 Pfam PF12344 Ultra-violet resistance protein B 555 597 2.8E-22 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 SUPERFAMILY SSF52540 36 84 1.73E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03630 b96a1186f64619420855bcdcbc25b112 663 SUPERFAMILY SSF52540 473 597 1.73E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02380 4248bff1d3b1d50389038d967b4570b4 487 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 412 432 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CB4_RS02380 4248bff1d3b1d50389038d967b4570b4 487 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 32 430 3.7E-97 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CB4_RS02380 4248bff1d3b1d50389038d967b4570b4 487 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 154 179 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CB4_RS02380 4248bff1d3b1d50389038d967b4570b4 487 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 4 486 2.6E-225 T 29-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 CB4_RS02380 4248bff1d3b1d50389038d967b4570b4 487 Pfam PF00474 Sodium:solute symporter family 32 430 6.3E-111 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 206 222 - T 29-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 SUPERFAMILY SSF48150 18 236 2.2E-75 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 SUPERFAMILY SSF55811 234 370 5.33E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 Pfam PF00633 Helix-hairpin-helix motif 113 142 5.2E-8 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 SMART SM00478 53 204 4.4E-54 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 Gene3D G3DSA:1.10.1670.10 132 239 2.6E-36 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 21 285 2.7E-103 T 29-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 49 179 1.4E-20 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 SMART SM00525 205 225 0.0037 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 Pfam PF14815 NUDIX domain 249 368 2.5E-21 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 Gene3D G3DSA:1.10.340.30 35 131 1.0E-33 T 29-03-2018 CB4_RS19300 392d1a38d177ef30a8283855a972e309 379 Gene3D G3DSA:3.90.79.10 240 377 6.1E-20 T 29-03-2018 CB4_RS08370 3176cb5a9cc939a0ea3469ccfc06d084 310 Pfam PF01479 S4 domain 21 68 4.1E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS08370 3176cb5a9cc939a0ea3469ccfc06d084 310 Pfam PF00849 RNA pseudouridylate synthase 95 249 1.7E-33 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS08370 3176cb5a9cc939a0ea3469ccfc06d084 310 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 19 306 3.8E-96 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS08370 3176cb5a9cc939a0ea3469ccfc06d084 310 Gene3D G3DSA:3.30.2350.10 86 310 2.5E-76 T 29-03-2018 CB4_RS08370 3176cb5a9cc939a0ea3469ccfc06d084 310 SMART SM00363 21 79 9.6E-4 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS08370 3176cb5a9cc939a0ea3469ccfc06d084 310 Gene3D G3DSA:3.10.290.10 6 79 5.5E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS08370 3176cb5a9cc939a0ea3469ccfc06d084 310 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 141 155 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS08370 3176cb5a9cc939a0ea3469ccfc06d084 310 SUPERFAMILY SSF55174 22 108 4.71E-9 T 29-03-2018 CB4_RS08370 3176cb5a9cc939a0ea3469ccfc06d084 310 SUPERFAMILY SSF55120 83 306 2.26E-79 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS08610 e759f4bfcab33d07b7e5bd6ca9191458 339 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 6 330 73.435 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS08610 e759f4bfcab33d07b7e5bd6ca9191458 339 SUPERFAMILY SSF53901 3 330 9.44E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS08610 e759f4bfcab33d07b7e5bd6ca9191458 339 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 111 189 3.5E-32 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS08610 e759f4bfcab33d07b7e5bd6ca9191458 339 Gene3D G3DSA:3.40.47.10 1 165 1.2E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS08610 e759f4bfcab33d07b7e5bd6ca9191458 339 Gene3D G3DSA:3.40.47.10 166 338 1.5E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS08610 e759f4bfcab33d07b7e5bd6ca9191458 339 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 330 4.2E-38 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS08610 e759f4bfcab33d07b7e5bd6ca9191458 339 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 8 330 2.6E-138 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 Pfam PF00890 FAD binding domain 6 392 1.9E-86 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 580 4.2E-275 T 29-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 SUPERFAMILY SSF56425 231 353 7.48E-31 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 9.3E-10 T 29-03-2018 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.3E-10 T 29-03-2018 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 Gene3D G3DSA:4.10.80.40 534 586 6.0E-7 T 29-03-2018 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 SUPERFAMILY SSF46977 445 586 8.63E-44 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 SUPERFAMILY SSF51905 357 429 3.86E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 SUPERFAMILY SSF51905 6 247 3.86E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 PIRSF PIRSF000171 2 240 1.4E-16 T 29-03-2018 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 PIRSF PIRSF000171 342 576 3.4E-15 T 29-03-2018 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 Gene3D G3DSA:3.50.50.60 4 417 4.0E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 Gene3D G3DSA:1.20.58.100 424 533 4.2E-26 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.9E-6 T 29-03-2018 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 1.9E-6 T 29-03-2018 CB4_RS05540 7a3cffaffb50ea44e1c506fb7f10ac18 594 Pfam PF02910 Fumarate reductase flavoprotein C-term 453 580 1.3E-42 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 SUPERFAMILY SSF54826 3 138 4.88E-59 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 Pfam PF03952 Enolase, N-terminal domain 4 134 2.7E-61 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 SMART SM01192 139 425 6.4E-229 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 PIRSF PIRSF001400 1 425 4.9E-196 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 Gene3D G3DSA:3.20.20.120 128 428 4.3E-106 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 Hamap MF_00318 Enolase [eno]. 2 411 46.089 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 SMART SM01193 4 134 4.8E-96 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 ProSitePatterns PS00164 Enolase signature. 334 347 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 PRINTS PR00148 Enolase signature 107 123 1.9E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 PRINTS PR00148 Enolase signature 37 51 1.9E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 PRINTS PR00148 Enolase signature 161 174 1.9E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 PRINTS PR00148 Enolase signature 311 322 1.9E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 PRINTS PR00148 Enolase signature 363 380 1.9E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 PRINTS PR00148 Enolase signature 334 348 1.9E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 SUPERFAMILY SSF51604 138 425 1.7E-130 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 6.7E-215 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 Gene3D G3DSA:3.30.390.10 3 127 3.9E-54 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03875 7c1b218d4c4a3deae797c9e8d126e159 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 424 1.0E-136 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS15550 b8302b37a564c83d88b71d89777f64e9 125 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 12 124 6.9E-16 T 29-03-2018 IPR006524 Transcription activator, ArpU family CB4_RS06140 53db4e0f1cfbe964c0321caeed45e04c 597 SUPERFAMILY SSF56601 200 408 1.13E-71 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS06140 53db4e0f1cfbe964c0321caeed45e04c 597 SUPERFAMILY SSF56601 443 590 1.13E-71 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS06140 53db4e0f1cfbe964c0321caeed45e04c 597 Gene3D G3DSA:3.90.1310.10 23 245 9.5E-18 T 29-03-2018 CB4_RS06140 53db4e0f1cfbe964c0321caeed45e04c 597 SUPERFAMILY SSF56519 55 235 6.28E-17 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CB4_RS06140 53db4e0f1cfbe964c0321caeed45e04c 597 Gene3D G3DSA:3.40.710.10 254 597 1.7E-80 T 29-03-2018 CB4_RS06140 53db4e0f1cfbe964c0321caeed45e04c 597 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 234 2.1E-10 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CB4_RS06140 53db4e0f1cfbe964c0321caeed45e04c 597 Pfam PF00905 Penicillin binding protein transpeptidase domain 275 587 2.0E-61 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CB4_RS15460 f0adc8412b66ee4a60afb7e17b4d1971 147 Pfam PF09393 Phage tail tube protein 16 140 2.8E-8 T 29-03-2018 IPR018989 Phage tail tube protein CB4_RS15460 f0adc8412b66ee4a60afb7e17b4d1971 147 SUPERFAMILY SSF69279 16 142 4.25E-8 T 29-03-2018 CB4_RS15135 b8b078f2a1fefa8f875da7139f8a4a0d 366 SUPERFAMILY SSF56796 4 357 3.4E-110 T 29-03-2018 CB4_RS15135 b8b078f2a1fefa8f875da7139f8a4a0d 366 Gene3D G3DSA:3.40.50.1970 7 174 3.7E-46 T 29-03-2018 CB4_RS15135 b8b078f2a1fefa8f875da7139f8a4a0d 366 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 359 41.768 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CB4_RS15135 b8b078f2a1fefa8f875da7139f8a4a0d 366 Pfam PF01761 3-dehydroquinate synthase 70 326 2.2E-101 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CB4_RS15135 b8b078f2a1fefa8f875da7139f8a4a0d 366 Gene3D G3DSA:1.20.1090.10 175 363 5.8E-69 T 29-03-2018 CB4_RS15135 b8b078f2a1fefa8f875da7139f8a4a0d 366 PIRSF PIRSF001455 6 364 1.1E-105 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CB4_RS15135 b8b078f2a1fefa8f875da7139f8a4a0d 366 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 354 3.9E-118 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 Pfam PF02743 Cache domain 30 280 3.7E-35 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 443 627 3.6E-43 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 SMART SM00304 318 370 1.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 Gene3D G3DSA:1.10.287.1060 317 395 0.033 T 29-03-2018 CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 Gene3D G3DSA:3.30.450.20 24 175 8.4E-17 T 29-03-2018 CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 Gene3D G3DSA:3.30.450.20 176 297 2.9E-28 T 29-03-2018 CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 SUPERFAMILY SSF103190 119 199 3.4E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 Gene3D G3DSA:1.10.287.950 424 675 9.0E-59 T 29-03-2018 CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 SMART SM00283 399 674 3.3E-77 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 SUPERFAMILY SSF58104 338 372 1.44E-72 T 29-03-2018 CB4_RS14625 740b87d87bb857fe5997a70e20e54dc3 675 SUPERFAMILY SSF58104 405 674 1.44E-72 T 29-03-2018 CB4_RS09060 24a91a5dea39b4faf3dab95dedbfa045 181 SUPERFAMILY SSF56235 4 180 5.29E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS09060 24a91a5dea39b4faf3dab95dedbfa045 181 Pfam PF00227 Proteasome subunit 5 179 1.3E-23 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CB4_RS09060 24a91a5dea39b4faf3dab95dedbfa045 181 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 8 180 1.6E-83 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CB4_RS09060 24a91a5dea39b4faf3dab95dedbfa045 181 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 7 180 41.352 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CB4_RS09060 24a91a5dea39b4faf3dab95dedbfa045 181 Gene3D G3DSA:3.60.20.10 8 181 9.3E-26 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS09060 24a91a5dea39b4faf3dab95dedbfa045 181 PIRSF PIRSF039093 1 181 6.7E-85 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CB4_RS12330 7d866bd161d422ba2fa7c51d5abd8cb5 402 SUPERFAMILY SSF103473 10 400 1.31E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS12330 7d866bd161d422ba2fa7c51d5abd8cb5 402 PRINTS PR01988 Putative bacilysin exporter bacE signature 382 402 6.2E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CB4_RS12330 7d866bd161d422ba2fa7c51d5abd8cb5 402 PRINTS PR01988 Putative bacilysin exporter bacE signature 317 340 6.2E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CB4_RS12330 7d866bd161d422ba2fa7c51d5abd8cb5 402 PRINTS PR01988 Putative bacilysin exporter bacE signature 92 110 6.2E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CB4_RS12330 7d866bd161d422ba2fa7c51d5abd8cb5 402 Pfam PF07690 Major Facilitator Superfamily 29 367 1.8E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS12330 7d866bd161d422ba2fa7c51d5abd8cb5 402 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 18 395 1.6E-104 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CB4_RS12330 7d866bd161d422ba2fa7c51d5abd8cb5 402 Gene3D G3DSA:1.20.1250.20 7 206 3.3E-31 T 29-03-2018 CB4_RS12330 7d866bd161d422ba2fa7c51d5abd8cb5 402 Gene3D G3DSA:1.20.1250.20 207 402 5.2E-13 T 29-03-2018 CB4_RS16245 d0bef22db4ce64d275bde7e89877ff21 321 SMART SM00382 40 232 1.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS16245 d0bef22db4ce64d275bde7e89877ff21 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 301 4.4E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CB4_RS16245 d0bef22db4ce64d275bde7e89877ff21 321 SUPERFAMILY SSF52540 11 254 1.3E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS16245 d0bef22db4ce64d275bde7e89877ff21 321 Pfam PF00005 ABC transporter 32 182 9.8E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS16245 d0bef22db4ce64d275bde7e89877ff21 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 321 4.1E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CB4_RS16245 d0bef22db4ce64d275bde7e89877ff21 321 Gene3D G3DSA:3.40.50.300 9 321 6.2E-82 T 29-03-2018 CB4_RS16245 d0bef22db4ce64d275bde7e89877ff21 321 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS12745 5a2da3f3b1b93aa195220fa14d0eb920 180 Gene3D G3DSA:1.20.120.570 1 178 2.8E-6 T 29-03-2018 CB4_RS09410 9edc0ff6fb0f4034844d4437a7281b7f 384 Pfam PF13480 Acetyltransferase (GNAT) domain 200 325 7.4E-8 T 29-03-2018 CB4_RS09410 9edc0ff6fb0f4034844d4437a7281b7f 384 Gene3D G3DSA:3.40.630.30 192 373 1.7E-8 T 29-03-2018 CB4_RS09410 9edc0ff6fb0f4034844d4437a7281b7f 384 SUPERFAMILY SSF55729 196 363 4.87E-8 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS02865 e11bc23f3240deb70edeee0029e54e7f 298 Gene3D G3DSA:3.40.50.150 91 297 4.2E-41 T 29-03-2018 CB4_RS02865 e11bc23f3240deb70edeee0029e54e7f 298 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 200 206 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CB4_RS02865 e11bc23f3240deb70edeee0029e54e7f 298 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 35 293 4.0E-79 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CB4_RS02865 e11bc23f3240deb70edeee0029e54e7f 298 SUPERFAMILY SSF53335 14 294 9.77E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS02865 e11bc23f3240deb70edeee0029e54e7f 298 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 10 296 1.7E-64 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CB4_RS02865 e11bc23f3240deb70edeee0029e54e7f 298 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 12 297 39.718 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CB4_RS02865 e11bc23f3240deb70edeee0029e54e7f 298 Gene3D G3DSA:1.10.8.10 10 90 2.6E-24 T 29-03-2018 CB4_RS02865 e11bc23f3240deb70edeee0029e54e7f 298 Pfam PF05175 Methyltransferase small domain 107 206 1.6E-10 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 SUPERFAMILY SSF55874 485 653 7.07E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Pfam PF07695 7TM diverse intracellular signalling 209 405 3.6E-12 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Gene3D G3DSA:3.30.565.10 830 1013 1.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Pfam PF06580 Histidine kinase 821 900 1.3E-21 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 SMART SM00387 914 1015 0.012 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 SMART SM00387 542 653 1.1E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 637 650 1.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 613 631 1.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 596 606 1.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 592 1.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Gene3D G3DSA:3.30.565.10 501 662 2.2E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 SUPERFAMILY SSF55874 876 1012 3.14E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Pfam PF00512 His Kinase A (phospho-acceptor) domain 429 496 3.5E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 SMART SM00448 690 804 3.5E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Pfam PF00072 Response regulator receiver domain 692 804 5.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 SUPERFAMILY SSF47384 418 497 1.49E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Gene3D G3DSA:2.60.120.260 47 206 1.4E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Gene3D G3DSA:1.10.287.130 419 492 2.7E-14 T 29-03-2018 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 SMART SM00388 428 496 2.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Gene3D G3DSA:3.40.50.2300 685 829 2.6E-38 T 29-03-2018 CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 SUPERFAMILY SSF49785 53 193 5.1E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 543 651 2.1E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 919 1014 1.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09880 c7a946f433f1a39973f20539a89c9f30 1017 SUPERFAMILY SSF52172 689 841 5.98E-40 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS02775 9910621e1886807bfe6d67811d289a22 314 Pfam PF03308 ArgK protein 17 278 5.3E-97 T 29-03-2018 CB4_RS02775 9910621e1886807bfe6d67811d289a22 314 Gene3D G3DSA:1.20.5.170 3 40 1.4E-13 T 29-03-2018 CB4_RS02775 9910621e1886807bfe6d67811d289a22 314 SUPERFAMILY SSF52540 2 305 4.94E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02775 9910621e1886807bfe6d67811d289a22 314 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 11 305 1.7E-106 T 29-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CB4_RS02775 9910621e1886807bfe6d67811d289a22 314 Gene3D G3DSA:3.40.50.300 42 248 2.0E-37 T 29-03-2018 CB4_RS19110 979c28c91540ebc3a498e1b9c1af4f9a 317 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CB4_RS19110 979c28c91540ebc3a498e1b9c1af4f9a 317 SUPERFAMILY SSF51735 98 279 4.86E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS19110 979c28c91540ebc3a498e1b9c1af4f9a 317 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 210 3.0E-13 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CB4_RS19110 979c28c91540ebc3a498e1b9c1af4f9a 317 Gene3D G3DSA:3.40.50.720 108 281 1.7E-53 T 29-03-2018 CB4_RS19110 979c28c91540ebc3a498e1b9c1af4f9a 317 Gene3D G3DSA:3.40.50.720 1 107 7.2E-23 T 29-03-2018 CB4_RS19110 979c28c91540ebc3a498e1b9c1af4f9a 317 SUPERFAMILY SSF52283 1 129 7.65E-17 T 29-03-2018 CB4_RS19110 979c28c91540ebc3a498e1b9c1af4f9a 317 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 278 2.5E-59 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CB4_RS10620 6d04c3aded2dc381027cb7c925587940 149 SUPERFAMILY SSF54631 21 145 8.21E-36 T 29-03-2018 CB4_RS10620 6d04c3aded2dc381027cb7c925587940 149 SMART SM00116 94 141 6.7E-12 T 29-03-2018 IPR000644 CBS domain CB4_RS10620 6d04c3aded2dc381027cb7c925587940 149 SMART SM00116 30 77 3.1E-12 T 29-03-2018 IPR000644 CBS domain CB4_RS10620 6d04c3aded2dc381027cb7c925587940 149 Gene3D G3DSA:3.20.20.70 4 149 5.2E-33 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS10620 6d04c3aded2dc381027cb7c925587940 149 Pfam PF00571 CBS domain 23 76 6.7E-15 T 29-03-2018 IPR000644 CBS domain CB4_RS10620 6d04c3aded2dc381027cb7c925587940 149 Pfam PF00571 CBS domain 90 140 2.1E-13 T 29-03-2018 IPR000644 CBS domain CB4_RS14190 613c853f6da94b48f7a039cda6d163a8 390 Pfam PF00155 Aminotransferase class I and II 33 383 1.6E-64 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS14190 613c853f6da94b48f7a039cda6d163a8 390 Gene3D G3DSA:3.40.640.10 47 299 4.9E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS14190 613c853f6da94b48f7a039cda6d163a8 390 SUPERFAMILY SSF53383 5 386 4.49E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS14190 613c853f6da94b48f7a039cda6d163a8 390 Gene3D G3DSA:3.90.1150.10 300 387 4.7E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS04035 5f90a794213a897a18379a8245950d98 616 SUPERFAMILY SSF82282 4 370 2.75E-93 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CB4_RS04035 5f90a794213a897a18379a8245950d98 616 Pfam PF02574 Homocysteine S-methyltransferase 15 285 9.1E-50 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CB4_RS04035 5f90a794213a897a18379a8245950d98 616 SUPERFAMILY SSF51730 326 609 2.35E-71 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CB4_RS04035 5f90a794213a897a18379a8245950d98 616 Gene3D G3DSA:3.20.20.330 1 305 1.9E-77 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CB4_RS04035 5f90a794213a897a18379a8245950d98 616 Pfam PF02219 Methylenetetrahydrofolate reductase 325 579 1.1E-27 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CB4_RS04035 5f90a794213a897a18379a8245950d98 616 Gene3D G3DSA:3.20.20.220 306 615 3.3E-69 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CB4_RS04805 f377f83536dba26575a2cbe343fe40a4 560 SMART SM00304 202 255 3.8E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS04805 f377f83536dba26575a2cbe343fe40a4 560 Gene3D G3DSA:1.20.120.30 19 176 1.6E-21 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CB4_RS04805 f377f83536dba26575a2cbe343fe40a4 560 Pfam PF00672 HAMP domain 204 251 1.9E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS04805 f377f83536dba26575a2cbe343fe40a4 560 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 175 1.3E-33 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS04805 f377f83536dba26575a2cbe343fe40a4 560 Gene3D G3DSA:1.10.287.950 314 560 1.4E-47 T 29-03-2018 CB4_RS04805 f377f83536dba26575a2cbe343fe40a4 560 Gene3D G3DSA:1.10.287.1060 226 313 2.7E-5 T 29-03-2018 CB4_RS04805 f377f83536dba26575a2cbe343fe40a4 560 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 329 511 3.7E-41 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS04805 f377f83536dba26575a2cbe343fe40a4 560 SUPERFAMILY SSF158472 203 253 6.93E-12 T 29-03-2018 CB4_RS04805 f377f83536dba26575a2cbe343fe40a4 560 SUPERFAMILY SSF58104 303 559 3.53E-57 T 29-03-2018 CB4_RS04805 f377f83536dba26575a2cbe343fe40a4 560 SMART SM00283 284 559 2.1E-59 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS17405 ab354248d5309898714de1e17a08acc7 385 Pfam PF01098 Cell cycle protein 19 377 7.2E-83 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CB4_RS17405 ab354248d5309898714de1e17a08acc7 385 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 335 359 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CB4_RS17405 ab354248d5309898714de1e17a08acc7 385 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 17 377 1.6E-102 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 CB4_RS09225 84bad949bb404ceb4d624fa852929bc9 205 Gene3D G3DSA:3.40.1550.10 3 204 1.6E-59 T 29-03-2018 IPR028976 CheC-like domain CB4_RS09225 84bad949bb404ceb4d624fa852929bc9 205 SUPERFAMILY SSF103039 4 202 9.29E-58 T 29-03-2018 IPR028976 CheC-like domain CB4_RS09225 84bad949bb404ceb4d624fa852929bc9 205 Pfam PF04509 CheC-like family 108 143 3.2E-12 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CB4_RS09225 84bad949bb404ceb4d624fa852929bc9 205 Pfam PF04509 CheC-like family 9 46 9.2E-14 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CB4_RS01145 8c3dbefdb592f5372653cd101daf3fa9 165 SUPERFAMILY SSF160369 3 159 1.44E-54 T 29-03-2018 CB4_RS01145 8c3dbefdb592f5372653cd101daf3fa9 165 Pfam PF00466 Ribosomal protein L10 4 100 2.2E-29 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CB4_RS01145 8c3dbefdb592f5372653cd101daf3fa9 165 ProSitePatterns PS01109 Ribosomal protein L10 signature. 7 41 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01145 8c3dbefdb592f5372653cd101daf3fa9 165 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 5 142 3.0E-4 T 29-03-2018 CB4_RS01145 8c3dbefdb592f5372653cd101daf3fa9 165 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 2 160 29.116 T 29-03-2018 IPR022973 Ribosomal protein L10 CB4_RS09640 fed538ec50891ed3e5a4f41a3ca6e9f4 397 SUPERFAMILY SSF53901 216 397 7.4E-36 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09640 fed538ec50891ed3e5a4f41a3ca6e9f4 397 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 151 167 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CB4_RS09640 fed538ec50891ed3e5a4f41a3ca6e9f4 397 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 242 1.2E-32 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CB4_RS09640 fed538ec50891ed3e5a4f41a3ca6e9f4 397 Gene3D G3DSA:3.40.47.10 268 397 3.0E-18 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09640 fed538ec50891ed3e5a4f41a3ca6e9f4 397 SUPERFAMILY SSF53901 4 249 5.76E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09640 fed538ec50891ed3e5a4f41a3ca6e9f4 397 SMART SM00825 Beta-ketoacyl synthase 6 397 4.3E-9 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CB4_RS09640 fed538ec50891ed3e5a4f41a3ca6e9f4 397 Gene3D G3DSA:3.40.47.10 1 253 6.2E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09640 fed538ec50891ed3e5a4f41a3ca6e9f4 397 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 250 355 1.4E-13 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CB4_RS03095 5b272c3808d03dbaf0907ba0f7035f3c 295 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CB4_RS03095 5b272c3808d03dbaf0907ba0f7035f3c 295 SUPERFAMILY SSF117143 119 254 1.02E-11 T 29-03-2018 CB4_RS03095 5b272c3808d03dbaf0907ba0f7035f3c 295 Pfam PF00460 Flagella basal body rod protein 5 35 1.6E-11 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CB4_RS03095 5b272c3808d03dbaf0907ba0f7035f3c 295 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 219 290 2.9E-17 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CB4_RS03095 5b272c3808d03dbaf0907ba0f7035f3c 295 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 5 173 5.3E-24 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CB4_RS03275 e94529a91ffb7e0f2a88d6fb7336f2ce 217 Gene3D G3DSA:2.40.50.100 104 200 0.29 T 29-03-2018 CB4_RS03275 e94529a91ffb7e0f2a88d6fb7336f2ce 217 Gene3D G3DSA:2.40.50.100 40 103 2.0E-11 T 29-03-2018 CB4_RS03275 e94529a91ffb7e0f2a88d6fb7336f2ce 217 Pfam PF13437 HlyD family secretion protein 91 204 1.4E-10 T 29-03-2018 CB4_RS03275 e94529a91ffb7e0f2a88d6fb7336f2ce 217 SUPERFAMILY SSF51230 39 116 1.19E-5 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS11060 e80738b14b43b84d25eea641c31efa75 173 Pfam PF03551 Transcriptional regulator PadR-like family 8 79 7.7E-17 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CB4_RS11060 e80738b14b43b84d25eea641c31efa75 173 Pfam PF10400 Virulence activator alpha C-term 102 168 5.7E-5 T 29-03-2018 IPR018309 Transcription regulator PadR, C-terminal CB4_RS11060 e80738b14b43b84d25eea641c31efa75 173 SUPERFAMILY SSF46785 6 170 5.64E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS11060 e80738b14b43b84d25eea641c31efa75 173 Gene3D G3DSA:1.10.10.10 3 93 9.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 Pfam PF00672 HAMP domain 213 261 3.8E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 SMART SM00304 213 265 2.0E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 Gene3D G3DSA:1.10.287.950 323 571 7.5E-58 T 29-03-2018 CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 184 1.8E-40 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 421 450 5.5E-7 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 469 498 5.5E-7 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 308 337 5.5E-7 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 339 521 3.9E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 Gene3D G3DSA:1.20.120.30 26 185 5.7E-13 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 SUPERFAMILY SSF58104 300 568 1.44E-76 T 29-03-2018 CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 SUPERFAMILY SSF58104 233 267 1.44E-76 T 29-03-2018 CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 SMART SM00283 294 569 1.3E-89 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02165 9b39dafc7a7f575f89c26a35fa15562d 571 Gene3D G3DSA:1.10.287.1060 241 322 0.0011 T 29-03-2018 CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 SUPERFAMILY SSF54862 248 315 1.56E-16 T 29-03-2018 CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 13 196 8.1E-32 T 29-03-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 Gene3D G3DSA:3.30.70.20 267 297 1.4E-9 T 29-03-2018 CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 SUPERFAMILY SSF53323 12 196 3.01E-36 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 Gene3D G3DSA:3.30.70.20 298 329 2.6E-4 T 29-03-2018 CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 295 306 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 238 316 3.7E-17 T 29-03-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 Gene3D G3DSA:3.30.70.20 228 266 2.1E-4 T 29-03-2018 CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 21 192 8.4E-28 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 Gene3D G3DSA:3.40.920.10 11 207 4.4E-41 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CB4_RS15320 58b98be13dcfcae690b1d5fc76c1e48c 334 Pfam PF12838 4Fe-4S dicluster domain 255 309 4.1E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 SUPERFAMILY SSF51735 136 303 1.29E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 SUPERFAMILY SSF52283 305 360 2.89E-66 T 29-03-2018 CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 SUPERFAMILY SSF52283 1 136 2.89E-66 T 29-03-2018 CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 PIRSF PIRSF000183 1 371 5.0E-184 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 SMART SM01002 148 297 1.9E-87 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 Gene3D G3DSA:3.40.50.720 1 188 1.3E-44 T 29-03-2018 CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 Gene3D G3DSA:3.40.50.720 189 371 1.4E-43 T 29-03-2018 CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 1.4E-47 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 29-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 SMART SM01003 4 136 7.9E-78 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 353 1.8E-82 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CB4_RS04100 e154eb3f0e32fb158d09fec16f79bc16 376 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 2.7E-177 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CB4_RS06885 10e40d8cbbbebf3bca49f973498252f1 515 Pfam PF05954 Phage late control gene D protein (GPD) 94 208 1.0E-9 T 29-03-2018 CB4_RS06885 10e40d8cbbbebf3bca49f973498252f1 515 Gene3D G3DSA:2.40.50.260 326 416 4.3E-6 T 29-03-2018 CB4_RS06885 10e40d8cbbbebf3bca49f973498252f1 515 Gene3D G3DSA:3.55.50.10 138 228 2.8E-13 T 29-03-2018 CB4_RS06885 10e40d8cbbbebf3bca49f973498252f1 515 SUPERFAMILY SSF69279 51 214 1.11E-23 T 29-03-2018 CB4_RS14925 1dbd3908418dfebc18faf53e0cd1e9ec 509 Pfam PF01434 Peptidase family M41 301 462 3.8E-33 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CB4_RS14925 1dbd3908418dfebc18faf53e0cd1e9ec 509 SMART SM00382 98 242 6.7E-22 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS14925 1dbd3908418dfebc18faf53e0cd1e9ec 509 SUPERFAMILY SSF52540 64 311 4.5E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14925 1dbd3908418dfebc18faf53e0cd1e9ec 509 Gene3D G3DSA:3.40.50.300 53 247 1.4E-52 T 29-03-2018 CB4_RS14925 1dbd3908418dfebc18faf53e0cd1e9ec 509 ProSitePatterns PS00674 AAA-protein family signature. 210 228 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CB4_RS14925 1dbd3908418dfebc18faf53e0cd1e9ec 509 SUPERFAMILY SSF140990 323 497 3.66E-41 T 29-03-2018 CB4_RS14925 1dbd3908418dfebc18faf53e0cd1e9ec 509 Gene3D G3DSA:1.10.8.60 248 315 2.5E-22 T 29-03-2018 CB4_RS14925 1dbd3908418dfebc18faf53e0cd1e9ec 509 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 102 239 5.9E-42 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 Gene3D G3DSA:3.30.70.870 294 373 9.2E-29 T 29-03-2018 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 SUPERFAMILY SSF54980 298 376 2.99E-19 T 29-03-2018 IPR035647 EF-G domain III/V-like CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 Gene3D G3DSA:3.30.70.240 396 556 1.1E-30 T 29-03-2018 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 SMART SM00838 404 492 1.0E-4 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 Gene3D G3DSA:3.40.50.300 5 191 1.6E-34 T 29-03-2018 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 Hamap MF_00071 Elongation factor 4 [lepA]. 1 604 312.915 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 Pfam PF03144 Elongation factor Tu domain 2 211 281 3.2E-10 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 SUPERFAMILY SSF54980 405 500 4.56E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 Pfam PF00009 Elongation factor Tu GTP binding domain 9 187 1.0E-52 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 Gene3D G3DSA:2.40.30.10 194 293 9.1E-26 T 29-03-2018 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 Pfam PF00679 Elongation factor G C-terminus 405 492 2.3E-23 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 SUPERFAMILY SSF52540 2 236 8.86E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.0E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 PRINTS PR00315 GTP-binding elongation factor signature 80 90 1.0E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 PRINTS PR00315 GTP-binding elongation factor signature 55 63 1.0E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 PRINTS PR00315 GTP-binding elongation factor signature 132 141 1.0E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 PRINTS PR00315 GTP-binding elongation factor signature 96 107 1.0E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 Pfam PF06421 GTP-binding protein LepA C-terminus 494 600 6.5E-54 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 178 8.1E-18 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS06660 c903c262f82d6f85ec5fbef3a65d7b83 604 TIGRFAM TIGR01393 lepA: elongation factor 4 9 602 0.0 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 SUPERFAMILY SSF51735 6 198 3.14E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 SMART SM00984 324 420 1.1E-22 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 6 416 1.5E-108 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 SUPERFAMILY SSF52413 311 421 1.24E-22 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 Gene3D G3DSA:3.40.50.720 231 429 5.0E-47 T 29-03-2018 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 Gene3D G3DSA:3.40.50.720 2 209 2.4E-37 T 29-03-2018 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 SUPERFAMILY SSF48179 207 297 7.99E-23 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 Gene3D G3DSA:1.20.5.170 210 230 5.4E-5 T 29-03-2018 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 297 1.7E-22 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 324 417 9.8E-19 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 6 189 2.1E-41 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 PIRSF PIRSF500136 1 430 6.9E-113 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CB4_RS05410 8ab28c546379c4fc792e0e6fb5873cf0 431 PIRSF PIRSF000124 5 427 4.0E-69 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CB4_RS18165 de74e380e9e50fd15b532cd1c91d7eab 495 SMART SM00382 29 217 2.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS18165 de74e380e9e50fd15b532cd1c91d7eab 495 SMART SM00382 278 472 7.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS18165 de74e380e9e50fd15b532cd1c91d7eab 495 Gene3D G3DSA:3.40.50.300 1 230 1.2E-60 T 29-03-2018 CB4_RS18165 de74e380e9e50fd15b532cd1c91d7eab 495 Gene3D G3DSA:3.40.50.300 258 488 1.6E-41 T 29-03-2018 CB4_RS18165 de74e380e9e50fd15b532cd1c91d7eab 495 SUPERFAMILY SSF52540 267 480 7.83E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS18165 de74e380e9e50fd15b532cd1c91d7eab 495 SUPERFAMILY SSF52540 3 221 3.33E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS18165 de74e380e9e50fd15b532cd1c91d7eab 495 Pfam PF00005 ABC transporter 20 170 1.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS18165 de74e380e9e50fd15b532cd1c91d7eab 495 Pfam PF00005 ABC transporter 269 423 8.7E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS18165 de74e380e9e50fd15b532cd1c91d7eab 495 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 Gene3D G3DSA:2.60.40.420 358 497 8.4E-34 T 29-03-2018 IPR008972 Cupredoxin CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 SUPERFAMILY SSF49503 86 215 2.45E-36 T 29-03-2018 IPR008972 Cupredoxin CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 ProSitePatterns PS00079 Multicopper oxidases signature 1. 476 496 - T 29-03-2018 IPR033138 Multicopper oxidases, conserved site CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 Gene3D G3DSA:2.60.40.420 227 350 1.4E-13 T 29-03-2018 IPR008972 Cupredoxin CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 Pfam PF07732 Multicopper oxidase 100 214 3.6E-37 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 SUPERFAMILY SSF49503 232 312 7.25E-11 T 29-03-2018 IPR008972 Cupredoxin CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 Gene3D G3DSA:2.60.40.420 57 215 6.5E-35 T 29-03-2018 IPR008972 Cupredoxin CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 PRINTS PR00695 Copper containing nitrite reductase signature 90 108 2.7E-5 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 PRINTS PR00695 Copper containing nitrite reductase signature 116 132 2.7E-5 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 PRINTS PR00695 Copper containing nitrite reductase signature 179 194 2.7E-5 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 ProSitePatterns PS00080 Multicopper oxidases signature 2. 481 492 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 Pfam PF07731 Multicopper oxidase 399 496 3.4E-25 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CB4_RS19220 57af29115b4ee83449d6be7a86cf9eca 516 SUPERFAMILY SSF49503 359 499 6.55E-33 T 29-03-2018 IPR008972 Cupredoxin CB4_RS12390 d34bc01824ad0ea6e03d258a480a2bae 368 SUPERFAMILY SSF51717 13 228 4.79E-15 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS12390 d34bc01824ad0ea6e03d258a480a2bae 368 Gene3D G3DSA:3.20.20.120 14 227 1.4E-22 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CB4_RS12390 d34bc01824ad0ea6e03d258a480a2bae 368 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 2 352 34.938 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CB4_RS12390 d34bc01824ad0ea6e03d258a480a2bae 368 PIRSF PIRSF004640 1 357 2.9E-155 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CB4_RS12390 d34bc01824ad0ea6e03d258a480a2bae 368 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 4 347 3.2E-134 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CB4_RS12390 d34bc01824ad0ea6e03d258a480a2bae 368 SUPERFAMILY SSF56014 261 352 9.6E-14 T 29-03-2018 CB4_RS12390 d34bc01824ad0ea6e03d258a480a2bae 368 Pfam PF04551 GcpE protein 7 348 8.9E-143 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 SUPERFAMILY SSF48163 317 484 4.84E-43 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 SUPERFAMILY SSF52374 4 316 2.68E-114 T 29-03-2018 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 Gene3D G3DSA:3.40.50.620 128 246 1.1E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 485 9.0E-176 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 Gene3D G3DSA:1.10.1160.10 247 333 9.3E-34 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 Gene3D G3DSA:1.10.8.70 336 384 5.2E-9 T 29-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 Gene3D G3DSA:3.40.50.620 5 127 1.7E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 484 33.424 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 Gene3D G3DSA:1.10.10.350 386 490 1.8E-24 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 8.0E-29 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 8.0E-29 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 8.0E-29 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 8.0E-29 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 8.0E-29 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CB4_RS01215 8facf583096f78ce3c62a82327d32292 492 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 7.1E-118 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CB4_RS08230 55fb031c3a1bcd09f86af91f031c72e3 637 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 14 636 1.7E-228 T 29-03-2018 IPR011927 Stage V sporulation protein D CB4_RS08230 55fb031c3a1bcd09f86af91f031c72e3 637 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 555 6.6E-83 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CB4_RS08230 55fb031c3a1bcd09f86af91f031c72e3 637 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 200 4.2E-25 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CB4_RS08230 55fb031c3a1bcd09f86af91f031c72e3 637 Gene3D G3DSA:3.90.1310.10 24 220 6.7E-50 T 29-03-2018 CB4_RS08230 55fb031c3a1bcd09f86af91f031c72e3 637 SMART SM00740 578 636 5.3E-8 T 29-03-2018 IPR005543 PASTA domain CB4_RS08230 55fb031c3a1bcd09f86af91f031c72e3 637 Gene3D G3DSA:3.40.710.10 221 586 6.7E-96 T 29-03-2018 CB4_RS08230 55fb031c3a1bcd09f86af91f031c72e3 637 SUPERFAMILY SSF54184 582 635 9.94E-8 T 29-03-2018 CB4_RS08230 55fb031c3a1bcd09f86af91f031c72e3 637 SUPERFAMILY SSF56601 170 567 2.82E-101 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS08230 55fb031c3a1bcd09f86af91f031c72e3 637 SUPERFAMILY SSF56519 53 219 9.03E-47 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CB4_RS08230 55fb031c3a1bcd09f86af91f031c72e3 637 Pfam PF03793 PASTA domain 582 635 5.6E-6 T 29-03-2018 IPR005543 PASTA domain CB4_RS19855 fce960ae00f68dd9bcb1cae0eef17ce1 183 SUPERFAMILY SSF54637 10 153 9.39E-43 T 29-03-2018 IPR029069 HotDog domain CB4_RS19855 fce960ae00f68dd9bcb1cae0eef17ce1 183 Gene3D G3DSA:3.10.129.10 142 179 0.084 T 29-03-2018 CB4_RS19855 fce960ae00f68dd9bcb1cae0eef17ce1 183 Gene3D G3DSA:3.10.129.10 1 141 1.6E-46 T 29-03-2018 CB4_RS19855 fce960ae00f68dd9bcb1cae0eef17ce1 183 Pfam PF03061 Thioesterase superfamily 27 98 8.5E-17 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS14960 09048dce96636d322174f166681934d9 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 121 4.6E-59 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CB4_RS14960 09048dce96636d322174f166681934d9 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 77.338 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CB4_RS14960 09048dce96636d322174f166681934d9 127 Pfam PF02261 Aspartate decarboxylase 1 114 2.1E-55 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CB4_RS14960 09048dce96636d322174f166681934d9 127 Gene3D G3DSA:2.40.40.20 1 117 2.6E-57 T 29-03-2018 CB4_RS14960 09048dce96636d322174f166681934d9 127 PIRSF PIRSF006246 1 126 5.6E-56 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CB4_RS14960 09048dce96636d322174f166681934d9 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 98 3.0E-39 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CB4_RS14960 09048dce96636d322174f166681934d9 127 SUPERFAMILY SSF50692 1 120 8.08E-53 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CB4_RS18355 51f122ee3e5ae0a374e09b3c51a6e257 222 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 6 221 1.5E-67 T 29-03-2018 IPR014205 Sporulation protein YtaF CB4_RS18355 51f122ee3e5ae0a374e09b3c51a6e257 222 Pfam PF02659 Putative manganese efflux pump 135 218 5.1E-11 T 29-03-2018 IPR003810 Putative manganese efflux pump CB4_RS18355 51f122ee3e5ae0a374e09b3c51a6e257 222 Pfam PF02659 Putative manganese efflux pump 4 81 2.9E-10 T 29-03-2018 IPR003810 Putative manganese efflux pump CB4_RS15705 b30962047471b3718853d57da118d0b8 361 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 5 123 8.7E-8 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CB4_RS15705 b30962047471b3718853d57da118d0b8 361 Gene3D G3DSA:3.40.50.720 3 140 1.4E-12 T 29-03-2018 CB4_RS15705 b30962047471b3718853d57da118d0b8 361 Gene3D G3DSA:3.30.360.10 141 320 9.8E-4 T 29-03-2018 CB4_RS15705 b30962047471b3718853d57da118d0b8 361 SUPERFAMILY SSF51735 3 138 2.5E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 SMART SM00283 381 656 3.4E-66 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 SUPERFAMILY SSF58104 320 354 2.22E-67 T 29-03-2018 CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 SUPERFAMILY SSF58104 387 655 2.22E-67 T 29-03-2018 CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 Gene3D G3DSA:3.30.450.20 34 179 4.0E-11 T 29-03-2018 CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 Pfam PF02743 Cache domain 40 261 9.5E-29 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 Pfam PF00672 HAMP domain 301 348 2.4E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 427 609 1.4E-41 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 Gene3D G3DSA:3.30.450.20 180 278 9.7E-23 T 29-03-2018 CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 Gene3D G3DSA:1.10.287.950 306 408 2.6E-10 T 29-03-2018 CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 Gene3D G3DSA:1.10.287.950 409 657 1.2E-51 T 29-03-2018 CB4_RS06085 c6cef2f13708be4d36a00bb026197bee 657 SMART SM00304 300 352 1.2E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS06390 fcee8e780730170f3bfab44c7ed754d4 421 Pfam PF01757 Acyltransferase family 63 388 2.5E-35 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CB4_RS14435 756c9e4e26696d059bc7eed88f155618 179 Pfam PF08534 Redoxin 35 152 4.2E-13 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CB4_RS14435 756c9e4e26696d059bc7eed88f155618 179 SUPERFAMILY SSF52833 1 171 6.09E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS14435 756c9e4e26696d059bc7eed88f155618 179 Gene3D G3DSA:3.40.30.10 21 179 4.4E-23 T 29-03-2018 CB4_RS14435 756c9e4e26696d059bc7eed88f155618 179 ProSitePatterns PS00194 Thioredoxin family active site. 61 79 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CB4_RS05830 17b3cb4b400731d5519866b3fc41bd2a 265 SUPERFAMILY SSF52540 4 246 1.25E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05830 17b3cb4b400731d5519866b3fc41bd2a 265 Gene3D G3DSA:3.40.50.300 1 244 7.2E-56 T 29-03-2018 CB4_RS05830 17b3cb4b400731d5519866b3fc41bd2a 265 PIRSF PIRSF003092 1 265 1.4E-93 T 29-03-2018 IPR025501 ATP binding protein MinD CB4_RS05830 17b3cb4b400731d5519866b3fc41bd2a 265 Pfam PF13614 AAA domain 4 158 2.2E-23 T 29-03-2018 IPR025669 AAA domain CB4_RS05830 17b3cb4b400731d5519866b3fc41bd2a 265 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 262 1.2E-119 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 CB4_RS00075 0bbb22213ca91830d2d2b7320fc0875c 243 Pfam PF01522 Polysaccharide deacetylase 41 158 6.1E-36 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS00075 0bbb22213ca91830d2d2b7320fc0875c 243 SUPERFAMILY SSF88713 7 233 3.78E-67 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS00075 0bbb22213ca91830d2d2b7320fc0875c 243 Gene3D G3DSA:3.20.20.370 20 242 1.3E-62 T 29-03-2018 CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 2.1E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 Gene3D G3DSA:1.10.10.10 127 210 1.1E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 SUPERFAMILY SSF46894 136 209 1.67E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 SUPERFAMILY SSF52172 1 133 1.71E-33 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 Gene3D G3DSA:3.40.50.2300 1 126 5.3E-34 T 29-03-2018 CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 SMART SM00448 2 115 8.8E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 SMART SM00421 146 203 6.6E-28 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS11040 30508c38010c2ef38844fd30ba71524a 210 Pfam PF00072 Response regulator receiver domain 4 115 7.8E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS18425 7f2f9880a1846502021756cb5dff327a 293 SUPERFAMILY SSF52096 36 287 3.91E-82 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS18425 7f2f9880a1846502021756cb5dff327a 293 Gene3D G3DSA:3.90.226.10 23 293 2.9E-69 T 29-03-2018 CB4_RS18425 7f2f9880a1846502021756cb5dff327a 293 Pfam PF01039 Carboxyl transferase domain 71 247 2.1E-17 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CB4_RS18425 7f2f9880a1846502021756cb5dff327a 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 171 189 1.0E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18425 7f2f9880a1846502021756cb5dff327a 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 237 248 1.0E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18425 7f2f9880a1846502021756cb5dff327a 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 208 225 1.0E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18425 7f2f9880a1846502021756cb5dff327a 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 259 268 1.0E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18425 7f2f9880a1846502021756cb5dff327a 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 137 151 1.0E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18425 7f2f9880a1846502021756cb5dff327a 293 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 23 289 1.2E-125 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS18425 7f2f9880a1846502021756cb5dff327a 293 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 289 39.658 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS01155 8b5fa6e9c353d841deef1bc9e4fd181f 234 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 4.6E-108 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CB4_RS01155 8b5fa6e9c353d841deef1bc9e4fd181f 234 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 45.251 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CB4_RS01155 8b5fa6e9c353d841deef1bc9e4fd181f 234 Pfam PF00687 Ribosomal protein L1p/L10e family 30 220 4.5E-60 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CB4_RS01155 8b5fa6e9c353d841deef1bc9e4fd181f 234 Gene3D G3DSA:3.40.50.790 68 148 2.2E-38 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CB4_RS01155 8b5fa6e9c353d841deef1bc9e4fd181f 234 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS01155 8b5fa6e9c353d841deef1bc9e4fd181f 234 PIRSF PIRSF002155 1 227 8.9E-82 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS01155 8b5fa6e9c353d841deef1bc9e4fd181f 234 SUPERFAMILY SSF56808 7 225 1.15E-85 T 29-03-2018 IPR023674 Ribosomal protein L1-like CB4_RS01155 8b5fa6e9c353d841deef1bc9e4fd181f 234 Gene3D G3DSA:3.30.190.20 149 228 4.7E-22 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 Gene3D G3DSA:3.40.50.300 72 283 2.0E-48 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 Pfam PF13481 AAA domain 74 223 3.3E-17 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 Pfam PF13541 Subunit ChlI of Mg-chelatase 347 431 6.8E-10 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 Gene3D G3DSA:3.30.230.10 284 458 7.7E-31 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 453 3.1E-208 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 PRINTS PR01874 DNA repair protein radA signature 214 242 5.2E-95 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 PRINTS PR01874 DNA repair protein radA signature 323 346 5.2E-95 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 PRINTS PR01874 DNA repair protein radA signature 249 275 5.2E-95 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 PRINTS PR01874 DNA repair protein radA signature 83 111 5.2E-95 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 PRINTS PR01874 DNA repair protein radA signature 125 142 5.2E-95 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 PRINTS PR01874 DNA repair protein radA signature 175 199 5.2E-95 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 PRINTS PR01874 DNA repair protein radA signature 10 34 5.2E-95 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 Hamap MF_01498 DNA repair protein RadA [radA]. 21 457 44.407 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 SMART SM00382 91 245 2.4E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 SUPERFAMILY SSF52540 70 294 2.77E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 Gene3D G3DSA:2.20.25.10 1 19 0.035 T 29-03-2018 CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 SUPERFAMILY SSF54211 256 270 2.31E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS01250 55c67cab55dcc5cef4fc3127e1decbbd 459 SUPERFAMILY SSF54211 304 455 2.31E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS04700 5b263d498085c971510f6864aaa5df6c 264 Gene3D G3DSA:1.10.1740.10 3 88 1.7E-10 T 29-03-2018 CB4_RS04700 5b263d498085c971510f6864aaa5df6c 264 SUPERFAMILY SSF88946 6 88 9.22E-16 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS04700 5b263d498085c971510f6864aaa5df6c 264 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 6 228 6.9E-74 T 29-03-2018 IPR014244 RNA polymerase sigma-I type CB4_RS04700 5b263d498085c971510f6864aaa5df6c 264 PIRSF PIRSF038953 1 242 1.1E-60 T 29-03-2018 IPR014244 RNA polymerase sigma-I type CB4_RS04700 5b263d498085c971510f6864aaa5df6c 264 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 3 230 27.028 T 29-03-2018 IPR014244 RNA polymerase sigma-I type CB4_RS04700 5b263d498085c971510f6864aaa5df6c 264 Pfam PF04542 Sigma-70 region 2 19 89 4.7E-6 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 SUPERFAMILY SSF52343 231 386 3.8E-51 T 29-03-2018 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 Gene3D G3DSA:3.40.50.80 229 385 2.4E-38 T 29-03-2018 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 Pfam PF00175 Oxidoreductase NAD-binding domain 244 350 6.8E-19 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 Gene3D G3DSA:2.40.30.10 2 225 7.1E-50 T 29-03-2018 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 SUPERFAMILY SSF63380 12 232 1.6E-63 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 312 328 1.6E-28 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 281 292 1.6E-28 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 268 277 1.6E-28 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 52 62 1.6E-28 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 243 262 1.6E-28 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 173 180 1.6E-28 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 335 343 1.6E-28 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CB4_RS09530 02fa722b3c480c709ad50fc3a46a654b 386 Pfam PF00667 FAD binding domain 13 209 1.4E-34 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CB4_RS04370 a6f3b5feec11cf8bbbf994afdbf6a1ff 117 SUPERFAMILY SSF101697 3 100 8.5E-27 T 29-03-2018 IPR014938 Protein of unknown function DUF1811 CB4_RS04370 a6f3b5feec11cf8bbbf994afdbf6a1ff 117 Gene3D G3DSA:1.10.287.880 2 49 9.8E-16 T 29-03-2018 CB4_RS04370 a6f3b5feec11cf8bbbf994afdbf6a1ff 117 Gene3D G3DSA:2.30.30.340 50 100 1.2E-16 T 29-03-2018 CB4_RS04370 a6f3b5feec11cf8bbbf994afdbf6a1ff 117 Pfam PF08838 Protein of unknown function (DUF1811) 3 98 2.2E-30 T 29-03-2018 IPR014938 Protein of unknown function DUF1811 CB4_RS05170 9f109c53865023fc9314d62b637469b7 307 Gene3D G3DSA:3.40.50.1100 41 138 1.6E-35 T 29-03-2018 CB4_RS05170 9f109c53865023fc9314d62b637469b7 307 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 303 4.7E-108 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CB4_RS05170 9f109c53865023fc9314d62b637469b7 307 Gene3D G3DSA:3.40.50.1100 139 307 1.0E-55 T 29-03-2018 CB4_RS05170 9f109c53865023fc9314d62b637469b7 307 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 303 7.1E-107 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CB4_RS05170 9f109c53865023fc9314d62b637469b7 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CB4_RS05170 9f109c53865023fc9314d62b637469b7 307 SUPERFAMILY SSF53686 2 301 7.07E-98 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS05170 9f109c53865023fc9314d62b637469b7 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 291 2.3E-69 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS16025 63d927271db4477fa74b7d141313680b 155 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 9 154 31.172 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16025 63d927271db4477fa74b7d141313680b 155 Gene3D G3DSA:3.40.50.960 2 69 5.7E-24 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16025 63d927271db4477fa74b7d141313680b 155 Gene3D G3DSA:3.40.50.960 70 155 3.4E-42 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16025 63d927271db4477fa74b7d141313680b 155 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 1.2E-60 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16025 63d927271db4477fa74b7d141313680b 155 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 1.9E-59 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16025 63d927271db4477fa74b7d141313680b 155 SUPERFAMILY SSF52121 4 154 9.68E-64 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS06380 62b2ab4b841b5b26c1c1539f9e03892b 100 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 86 2.1E-12 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06380 62b2ab4b841b5b26c1c1539f9e03892b 100 Gene3D G3DSA:1.10.1270.10 6 100 1.5E-20 T 29-03-2018 CB4_RS06380 62b2ab4b841b5b26c1c1539f9e03892b 100 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 60 86 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06380 62b2ab4b841b5b26c1c1539f9e03892b 100 SUPERFAMILY SSF88659 6 89 3.27E-20 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06380 62b2ab4b841b5b26c1c1539f9e03892b 100 PRINTS PR00046 Major sigma-70 factor signature 75 86 6.1E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06380 62b2ab4b841b5b26c1c1539f9e03892b 100 PRINTS PR00046 Major sigma-70 factor signature 60 75 6.1E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06380 62b2ab4b841b5b26c1c1539f9e03892b 100 PRINTS PR00046 Major sigma-70 factor signature 39 51 6.1E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06380 62b2ab4b841b5b26c1c1539f9e03892b 100 Pfam PF04545 Sigma-70, region 4 37 87 1.7E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 Gene3D G3DSA:3.30.70.250 3 76 2.6E-39 T 29-03-2018 CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 Gene3D G3DSA:2.160.10.10 77 128 3.3E-11 T 29-03-2018 CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 Gene3D G3DSA:2.160.10.10 129 235 1.7E-31 T 29-03-2018 CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 1.2E-118 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 2.7E-36 T 29-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 SUPERFAMILY SSF51161 89 225 3.47E-49 T 29-03-2018 IPR011004 Trimeric LpxA-like CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 166 198 1.7E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 92 118 8.0E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 2.0E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS03955 85a4ac5d1cf40a781e348d86b554bb6b 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 46.503 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CB4_RS07540 b9935efe790fa1bb650ef2076a8393c7 299 Pfam PF00892 EamA-like transporter family 151 282 6.9E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS07540 b9935efe790fa1bb650ef2076a8393c7 299 Pfam PF00892 EamA-like transporter family 6 136 1.1E-8 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS07540 b9935efe790fa1bb650ef2076a8393c7 299 SUPERFAMILY SSF103481 42 136 2.48E-7 T 29-03-2018 CB4_RS07540 b9935efe790fa1bb650ef2076a8393c7 299 SUPERFAMILY SSF103481 202 283 2.09E-8 T 29-03-2018 CB4_RS11895 bb22ee70cf0c7ca482d4e945c57b30f8 267 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 71 135 3.3E-18 T 29-03-2018 CB4_RS11895 bb22ee70cf0c7ca482d4e945c57b30f8 267 Pfam PF07833 Copper amine oxidase N-terminal domain 241 265 1.5E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS11895 bb22ee70cf0c7ca482d4e945c57b30f8 267 Gene3D G3DSA:3.30.1380.10 6 135 3.2E-31 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS11895 bb22ee70cf0c7ca482d4e945c57b30f8 267 SUPERFAMILY SSF55166 6 135 2.12E-32 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS11895 bb22ee70cf0c7ca482d4e945c57b30f8 267 Gene3D G3DSA:3.30.457.10 239 267 4.1E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS00570 f5c4b0d4a0496330ca3173cfa3e5c2df 277 SUPERFAMILY SSF47413 35 85 5.32E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS00570 f5c4b0d4a0496330ca3173cfa3e5c2df 277 Pfam PF13560 Helix-turn-helix domain 11 90 1.1E-17 T 29-03-2018 CB4_RS00570 f5c4b0d4a0496330ca3173cfa3e5c2df 277 SMART SM00530 15 87 1.7E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS00570 f5c4b0d4a0496330ca3173cfa3e5c2df 277 Gene3D G3DSA:1.10.260.40 2 106 4.2E-15 T 29-03-2018 CB4_RS02540 eddddbee9b09d5593d7f389623b9d3c6 159 PIRSF PIRSF006181 1 159 3.5E-56 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CB4_RS02540 eddddbee9b09d5593d7f389623b9d3c6 159 SUPERFAMILY SSF55826 5 154 4.06E-38 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CB4_RS02540 eddddbee9b09d5593d7f389623b9d3c6 159 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 5 155 3.4E-50 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CB4_RS02540 eddddbee9b09d5593d7f389623b9d3c6 159 Gene3D G3DSA:3.90.960.10 1 159 1.4E-34 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CB4_RS02540 eddddbee9b09d5593d7f389623b9d3c6 159 Pfam PF04073 Aminoacyl-tRNA editing domain 33 146 4.4E-22 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CB4_RS07380 9408cf89457af7f880aa012dca457fc3 251 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 10 234 1.1E-37 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CB4_RS07380 9408cf89457af7f880aa012dca457fc3 251 SUPERFAMILY SSF51695 4 241 1.36E-71 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CB4_RS07380 9408cf89457af7f880aa012dca457fc3 251 Gene3D G3DSA:3.20.20.190 2 251 1.3E-70 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CB4_RS12000 917a2c095fda458fc98b512e1fc2ba77 481 Pfam PF00324 Amino acid permease 20 463 3.2E-133 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CB4_RS12000 917a2c095fda458fc98b512e1fc2ba77 481 ProSitePatterns PS00218 Amino acid permeases signature. 45 76 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CB4_RS12000 917a2c095fda458fc98b512e1fc2ba77 481 PIRSF PIRSF006060 1 474 5.8E-80 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS13185 ed1571e0847781592a23e9994138b5a2 530 PIRSF PIRSF500060 1 529 5.8E-210 T 29-03-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria CB4_RS13185 ed1571e0847781592a23e9994138b5a2 530 SUPERFAMILY SSF51395 167 527 6.74E-110 T 29-03-2018 CB4_RS13185 ed1571e0847781592a23e9994138b5a2 530 SUPERFAMILY SSF51395 5 127 6.74E-110 T 29-03-2018 CB4_RS13185 ed1571e0847781592a23e9994138b5a2 530 PIRSF PIRSF006429 1 528 1.4E-156 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein CB4_RS13185 ed1571e0847781592a23e9994138b5a2 530 Pfam PF01645 Conserved region in glutamate synthase 122 496 8.6E-99 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CB4_RS13185 ed1571e0847781592a23e9994138b5a2 530 Gene3D G3DSA:3.20.20.70 96 527 2.2E-91 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS18305 92280ce6c31d1015030a276e2fa9be5c 212 Gene3D G3DSA:2.40.10.220 100 209 6.3E-17 T 29-03-2018 CB4_RS18305 92280ce6c31d1015030a276e2fa9be5c 212 SUPERFAMILY SSF141371 100 168 9.81E-6 T 29-03-2018 CB4_RS18305 92280ce6c31d1015030a276e2fa9be5c 212 Pfam PF12945 Flagellar protein YcgR 7 91 2.8E-16 T 29-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal CB4_RS18305 92280ce6c31d1015030a276e2fa9be5c 212 Pfam PF07238 PilZ domain 100 201 4.8E-11 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CB4_RS18305 92280ce6c31d1015030a276e2fa9be5c 212 Gene3D G3DSA:2.30.110.10 4 99 1.7E-18 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS18080 c025af73ce782bfdf226112cfa584a45 237 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 128 179 5.4E-7 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CB4_RS06070 726fef973b7d2a9c06354bb029bf8031 203 SUPERFAMILY SSF50346 22 88 5.34E-9 T 29-03-2018 IPR011033 PRC-barrel-like CB4_RS06070 726fef973b7d2a9c06354bb029bf8031 203 Pfam PF05239 PRC-barrel domain 24 88 8.1E-9 T 29-03-2018 IPR027275 PRC-barrel domain CB4_RS06070 726fef973b7d2a9c06354bb029bf8031 203 Pfam PF05239 PRC-barrel domain 112 179 1.4E-8 T 29-03-2018 IPR027275 PRC-barrel domain CB4_RS06070 726fef973b7d2a9c06354bb029bf8031 203 SUPERFAMILY SSF50346 112 178 2.2E-8 T 29-03-2018 IPR011033 PRC-barrel-like CB4_RS06070 726fef973b7d2a9c06354bb029bf8031 203 Gene3D G3DSA:2.30.30.240 109 180 4.6E-9 T 29-03-2018 CB4_RS06070 726fef973b7d2a9c06354bb029bf8031 203 Gene3D G3DSA:2.30.30.240 21 92 1.2E-9 T 29-03-2018 CB4_RS17260 54424d8533407b208906d4506f25f0df 385 Gene3D G3DSA:1.20.1250.20 4 195 8.2E-32 T 29-03-2018 CB4_RS17260 54424d8533407b208906d4506f25f0df 385 SUPERFAMILY SSF103473 11 383 1.09E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS17260 54424d8533407b208906d4506f25f0df 385 Pfam PF07690 Major Facilitator Superfamily 17 345 1.6E-41 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS17260 54424d8533407b208906d4506f25f0df 385 PRINTS PR01035 Tetracycline resistance protein signature 135 157 3.7E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS17260 54424d8533407b208906d4506f25f0df 385 PRINTS PR01035 Tetracycline resistance protein signature 163 183 3.7E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS17260 54424d8533407b208906d4506f25f0df 385 PRINTS PR01035 Tetracycline resistance protein signature 22 38 3.7E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS17260 54424d8533407b208906d4506f25f0df 385 Gene3D G3DSA:1.20.1250.20 196 383 3.1E-21 T 29-03-2018 CB4_RS07280 6d618bcda2b934e1c4cc52c26e4197c0 182 SUPERFAMILY SSF50475 3 163 1.01E-37 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS07280 6d618bcda2b934e1c4cc52c26e4197c0 182 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 13 162 1.8E-25 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CB4_RS07280 6d618bcda2b934e1c4cc52c26e4197c0 182 Gene3D G3DSA:2.30.110.10 4 168 1.5E-28 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS08540 ef1745c036ed14c08c9432e66d40c209 558 SMART SM01121 229 558 5.7E-164 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain CB4_RS08540 ef1745c036ed14c08c9432e66d40c209 558 SMART SM01120 23 186 1.3E-69 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CB4_RS08540 ef1745c036ed14c08c9432e66d40c209 558 SUPERFAMILY SSF101473 3 188 8.76E-43 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CB4_RS08540 ef1745c036ed14c08c9432e66d40c209 558 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 1 558 3.5E-202 T 29-03-2018 IPR019986 DAK2 domain-containing protein YloV CB4_RS08540 ef1745c036ed14c08c9432e66d40c209 558 Pfam PF02734 DAK2 domain 23 185 2.6E-41 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CB4_RS08540 ef1745c036ed14c08c9432e66d40c209 558 Gene3D G3DSA:3.20.20.70 86 441 1.7E-4 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS08540 ef1745c036ed14c08c9432e66d40c209 558 Pfam PF13684 Dihydroxyacetone kinase family 230 558 1.8E-117 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain CB4_RS15065 bfdacb792fbf4b14ada860afdd6ee57d 197 SUPERFAMILY SSF88659 118 182 3.18E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15065 bfdacb792fbf4b14ada860afdd6ee57d 197 SUPERFAMILY SSF88946 3 105 6.28E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15065 bfdacb792fbf4b14ada860afdd6ee57d 197 Pfam PF04542 Sigma-70 region 2 22 92 2.1E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15065 bfdacb792fbf4b14ada860afdd6ee57d 197 Pfam PF08281 Sigma-70, region 4 127 175 1.8E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15065 bfdacb792fbf4b14ada860afdd6ee57d 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 181 4.0E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS15065 bfdacb792fbf4b14ada860afdd6ee57d 197 Gene3D G3DSA:1.10.10.10 96 184 1.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15065 bfdacb792fbf4b14ada860afdd6ee57d 197 Gene3D G3DSA:1.10.1740.10 2 95 1.3E-22 T 29-03-2018 CB4_RS19375 0909721ddcc16e8d04576951b698726a 451 Gene3D G3DSA:3.90.1150.10 324 447 6.5E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS19375 0909721ddcc16e8d04576951b698726a 451 SUPERFAMILY SSF53383 33 441 2.08E-134 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS19375 0909721ddcc16e8d04576951b698726a 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS19375 0909721ddcc16e8d04576951b698726a 451 PIRSF PIRSF000521 138 444 1.7E-40 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS19375 0909721ddcc16e8d04576951b698726a 451 PIRSF PIRSF000521 2 143 8.0E-11 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS19375 0909721ddcc16e8d04576951b698726a 451 Pfam PF00202 Aminotransferase class-III 36 440 3.8E-130 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS19375 0909721ddcc16e8d04576951b698726a 451 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 23 442 4.5E-188 T 29-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CB4_RS19375 0909721ddcc16e8d04576951b698726a 451 Gene3D G3DSA:3.40.640.10 72 323 2.3E-77 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS06455 8a8eaf04112e5bc02ab585eca02dee20 425 Pfam PF03600 Citrate transporter 16 367 3.3E-60 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CB4_RS06455 8a8eaf04112e5bc02ab585eca02dee20 425 PRINTS PR00758 Arsenical pump membrane protein signature 276 300 2.9E-11 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS06455 8a8eaf04112e5bc02ab585eca02dee20 425 PRINTS PR00758 Arsenical pump membrane protein signature 321 343 2.9E-11 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS06455 8a8eaf04112e5bc02ab585eca02dee20 425 PRINTS PR00758 Arsenical pump membrane protein signature 218 243 2.9E-11 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS06455 8a8eaf04112e5bc02ab585eca02dee20 425 PRINTS PR00758 Arsenical pump membrane protein signature 363 388 2.9E-11 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS06455 8a8eaf04112e5bc02ab585eca02dee20 425 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 2.9E-11 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS03115 80b124959aabfc266cf9a331c468ef2c 391 Gene3D G3DSA:3.90.1150.10 300 391 4.7E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS03115 80b124959aabfc266cf9a331c468ef2c 391 Gene3D G3DSA:3.40.640.10 49 299 8.9E-69 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS03115 80b124959aabfc266cf9a331c468ef2c 391 SUPERFAMILY SSF53383 9 390 6.52E-124 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS03115 80b124959aabfc266cf9a331c468ef2c 391 Pfam PF00155 Aminotransferase class I and II 35 382 2.7E-71 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS03115 80b124959aabfc266cf9a331c468ef2c 391 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CB4_RS01790 f0063ce5b3d081031ffc1799a82ea3dc 216 Pfam PF02570 Precorrin-8X methylmutase 16 209 1.9E-79 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CB4_RS01790 f0063ce5b3d081031ffc1799a82ea3dc 216 SUPERFAMILY SSF63965 10 212 1.31E-73 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CB4_RS01790 f0063ce5b3d081031ffc1799a82ea3dc 216 Gene3D G3DSA:3.40.50.10230 10 216 4.0E-85 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CB4_RS00750 c9c81ddc00b84804ce96e08588668b1a 372 Gene3D G3DSA:3.40.50.300 119 334 5.2E-49 T 29-03-2018 CB4_RS00750 c9c81ddc00b84804ce96e08588668b1a 372 SUPERFAMILY SSF52540 125 367 2.49E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00750 c9c81ddc00b84804ce96e08588668b1a 372 Pfam PF01883 Iron-sulfur cluster assembly protein 4 69 2.5E-18 T 29-03-2018 IPR002744 MIP18 family-like CB4_RS00750 c9c81ddc00b84804ce96e08588668b1a 372 Gene3D G3DSA:3.30.300.130 1 94 1.3E-19 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CB4_RS00750 c9c81ddc00b84804ce96e08588668b1a 372 ProSitePatterns PS01215 Mrp family signature. 229 245 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 CB4_RS00750 c9c81ddc00b84804ce96e08588668b1a 372 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 126 364 2.9E-84 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CB4_RS00750 c9c81ddc00b84804ce96e08588668b1a 372 Hamap MF_02040 Iron-sulfur cluster carrier protein. 116 365 33.714 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CB4_RS00750 c9c81ddc00b84804ce96e08588668b1a 372 SUPERFAMILY SSF117916 2 86 1.28E-19 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 530 548 4.2E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 563 577 4.2E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 501 519 4.2E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 456 474 4.2E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 SMART SM01086 622 709 1.9E-25 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 SMART SM00382 452 598 5.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 SMART SM00382 124 266 1.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 SUPERFAMILY SSF52540 401 707 2.95E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 219 231 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 Gene3D G3DSA:3.40.50.300 85 266 5.4E-25 T 29-03-2018 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 Gene3D G3DSA:1.10.8.60 267 402 1.9E-37 T 29-03-2018 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 622 697 3.8E-22 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 Gene3D G3DSA:3.40.50.300 407 621 6.7E-49 T 29-03-2018 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 129 262 2.0E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 SUPERFAMILY SSF52540 86 399 1.39E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 Pfam PF02151 UvrB/uvrC motif 340 372 4.1E-5 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 Gene3D G3DSA:1.10.8.60 622 712 6.4E-20 T 29-03-2018 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 486 504 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CB4_RS13730 f57a3f358efc05bddf922965b431a5c0 713 Pfam PF07724 AAA domain (Cdc48 subfamily) 451 615 1.1E-50 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS16155 737fb26ecf8793569eee32dd215e6367 144 PRINTS PR00332 Histidine triad family signature 96 106 4.5E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CB4_RS16155 737fb26ecf8793569eee32dd215e6367 144 PRINTS PR00332 Histidine triad family signature 29 47 4.5E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CB4_RS16155 737fb26ecf8793569eee32dd215e6367 144 PRINTS PR00332 Histidine triad family signature 8 24 4.5E-18 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CB4_RS16155 737fb26ecf8793569eee32dd215e6367 144 ProSitePatterns PS00892 HIT domain signature. 89 107 - T 29-03-2018 IPR019808 Histidine triad, conserved site CB4_RS16155 737fb26ecf8793569eee32dd215e6367 144 SUPERFAMILY SSF54197 5 142 7.27E-49 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CB4_RS16155 737fb26ecf8793569eee32dd215e6367 144 Gene3D G3DSA:1.20.5.1170 120 141 4.9E-7 T 29-03-2018 CB4_RS16155 737fb26ecf8793569eee32dd215e6367 144 Gene3D G3DSA:3.30.428.10 1 116 3.9E-36 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CB4_RS16155 737fb26ecf8793569eee32dd215e6367 144 Pfam PF01230 HIT domain 15 109 4.7E-29 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 39.194 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 120 2.3E-40 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 3.5E-72 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 Gene3D G3DSA:3.40.50.720 140 263 7.2E-40 T 29-03-2018 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 SUPERFAMILY SSF51735 122 279 2.12E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 SUPERFAMILY SSF53223 1 121 1.53E-40 T 29-03-2018 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 Gene3D G3DSA:3.40.50.10860 11 139 2.3E-49 T 29-03-2018 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.1E-83 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.1E-83 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.1E-83 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.1E-83 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.1E-83 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.1E-83 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CB4_RS07965 e70871dec6826fa43750a3e61a5ec7c2 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.1E-83 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CB4_RS12145 3e1eadd7124908ba9f0e318b7d5f6185 298 Pfam PF03466 LysR substrate binding domain 87 290 6.5E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CB4_RS12145 3e1eadd7124908ba9f0e318b7d5f6185 298 SUPERFAMILY SSF53850 88 293 8.69E-39 T 29-03-2018 CB4_RS12145 3e1eadd7124908ba9f0e318b7d5f6185 298 Gene3D G3DSA:3.40.190.10 177 268 2.7E-18 T 29-03-2018 CB4_RS12145 3e1eadd7124908ba9f0e318b7d5f6185 298 SUPERFAMILY SSF46785 1 87 2.06E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12145 3e1eadd7124908ba9f0e318b7d5f6185 298 Gene3D G3DSA:3.40.190.10 91 176 6.8E-17 T 29-03-2018 CB4_RS12145 3e1eadd7124908ba9f0e318b7d5f6185 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.2E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS12145 3e1eadd7124908ba9f0e318b7d5f6185 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS12145 3e1eadd7124908ba9f0e318b7d5f6185 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS12145 3e1eadd7124908ba9f0e318b7d5f6185 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS12145 3e1eadd7124908ba9f0e318b7d5f6185 298 Gene3D G3DSA:1.10.10.10 1 90 2.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02390 90ffd58e7ccf16267b027d6aad98212b 221 Pfam PF00578 AhpC/TSA family 9 138 4.0E-31 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS02390 90ffd58e7ccf16267b027d6aad98212b 221 Gene3D G3DSA:3.30.1020.10 155 221 3.3E-19 T 29-03-2018 CB4_RS02390 90ffd58e7ccf16267b027d6aad98212b 221 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 159 198 5.9E-9 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS02390 90ffd58e7ccf16267b027d6aad98212b 221 Hamap MF_00401 Peroxiredoxin. 7 219 47.189 T 29-03-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CB4_RS02390 90ffd58e7ccf16267b027d6aad98212b 221 Gene3D G3DSA:3.40.30.10 2 154 1.5E-33 T 29-03-2018 CB4_RS02390 90ffd58e7ccf16267b027d6aad98212b 221 PIRSF PIRSF000239 2 218 5.2E-73 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS02390 90ffd58e7ccf16267b027d6aad98212b 221 SUPERFAMILY SSF52833 7 219 1.91E-63 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS19210 6f8b6d15de0a578e9ada10149e30cfb1 215 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 211 96.39 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CB4_RS19210 6f8b6d15de0a578e9ada10149e30cfb1 215 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 19 207 4.9E-64 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CB4_RS19210 6f8b6d15de0a578e9ada10149e30cfb1 215 Gene3D G3DSA:3.40.225.10 7 214 1.8E-39 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CB4_RS19210 6f8b6d15de0a578e9ada10149e30cfb1 215 SMART SM01007 14 203 8.3E-35 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CB4_RS19210 6f8b6d15de0a578e9ada10149e30cfb1 215 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 16 200 6.2E-35 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CB4_RS19210 6f8b6d15de0a578e9ada10149e30cfb1 215 SUPERFAMILY SSF53639 10 208 6.47E-42 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CB4_RS04945 0a87824b387bca9ee2532ed56ee00ba6 226 Gene3D G3DSA:3.40.190.10 1 213 6.0E-8 T 29-03-2018 CB4_RS00770 9185e435b8081893a9c74db2f6feb900 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 28.036 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CB4_RS00770 9185e435b8081893a9c74db2f6feb900 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 142 7.7E-64 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00770 9185e435b8081893a9c74db2f6feb900 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 29-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CB4_RS00770 9185e435b8081893a9c74db2f6feb900 145 PIRSF PIRSF002181 1 144 1.3E-50 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CB4_RS00770 9185e435b8081893a9c74db2f6feb900 145 Gene3D G3DSA:3.90.1180.10 1 145 3.4E-61 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CB4_RS00770 9185e435b8081893a9c74db2f6feb900 145 Pfam PF00572 Ribosomal protein L13 15 139 1.0E-57 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CB4_RS00770 9185e435b8081893a9c74db2f6feb900 145 SUPERFAMILY SSF52161 5 143 5.36E-60 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CB4_RS06175 9aa9ce026e8f1c8d4730142fc104e127 239 Pfam PF04326 Putative DNA-binding domain 33 164 9.2E-10 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 CB4_RS01640 5fd93e60deb6efadd6cccd622ca0fb51 198 TIGRFAM TIGR00615 recR: recombination protein RecR 3 196 5.3E-87 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CB4_RS01640 5fd93e60deb6efadd6cccd622ca0fb51 198 Pfam PF13662 Toprim domain 80 171 7.2E-25 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS01640 5fd93e60deb6efadd6cccd622ca0fb51 198 SUPERFAMILY SSF111304 2 198 4.58E-77 T 29-03-2018 IPR023627 Recombination protein RecR CB4_RS01640 5fd93e60deb6efadd6cccd622ca0fb51 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 29-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CB4_RS01640 5fd93e60deb6efadd6cccd622ca0fb51 198 Gene3D G3DSA:3.40.1360.10 77 170 9.2E-40 T 29-03-2018 CB4_RS01640 5fd93e60deb6efadd6cccd622ca0fb51 198 Pfam PF02132 RecR protein 40 78 6.2E-16 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CB4_RS01640 5fd93e60deb6efadd6cccd622ca0fb51 198 Gene3D G3DSA:1.10.150.20 9 32 0.13 T 29-03-2018 CB4_RS01640 5fd93e60deb6efadd6cccd622ca0fb51 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 109.55 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CB4_RS01640 5fd93e60deb6efadd6cccd622ca0fb51 198 SMART SM00493 80 165 3.4E-16 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS18765 b82338498e2d9e1409c73b21b4a30226 214 Pfam PF04293 SpoVR like protein 3 152 3.5E-56 T 29-03-2018 IPR007390 Sporulation stage V, protein R CB4_RS12150 e17e0345c6d6e6b3245202c4463aa8ee 491 SUPERFAMILY SSF56645 4 273 2.23E-81 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CB4_RS12150 e17e0345c6d6e6b3245202c4463aa8ee 491 SUPERFAMILY SSF47203 263 479 1.49E-58 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS12150 e17e0345c6d6e6b3245202c4463aa8ee 491 PIRSF PIRSF000331 1 488 9.6E-173 T 29-03-2018 IPR004925 HpaB/PvcC/4-BUDH CB4_RS12150 e17e0345c6d6e6b3245202c4463aa8ee 491 Gene3D G3DSA:2.40.110.10 144 274 1.5E-18 T 29-03-2018 CB4_RS12150 e17e0345c6d6e6b3245202c4463aa8ee 491 Gene3D G3DSA:1.10.3140.10 3 143 1.8E-51 T 29-03-2018 CB4_RS12150 e17e0345c6d6e6b3245202c4463aa8ee 491 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 279 478 1.3E-62 T 29-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal CB4_RS12150 e17e0345c6d6e6b3245202c4463aa8ee 491 TIGRFAM TIGR02309 HpaB-1: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 3 480 8.0E-225 T 29-03-2018 IPR012687 4-HPA 3-monooxygenase large component, Deinococcus-type GO:0010124|GO:0016712|GO:0050660 KEGG: 00350+1.14.14.9|MetaCyc: PWY-7431 CB4_RS12150 e17e0345c6d6e6b3245202c4463aa8ee 491 Gene3D G3DSA:1.20.140.10 283 479 4.5E-68 T 29-03-2018 CB4_RS12150 e17e0345c6d6e6b3245202c4463aa8ee 491 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 272 9.4E-103 T 29-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 305 364 8.7E-15 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 SUPERFAMILY SSF55874 367 551 3.67E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 SUPERFAMILY SSF50341 552 685 1.7E-34 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Pfam PF07194 P2 response regulator binding domain 177 255 3.5E-26 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 413 552 5.0E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Gene3D G3DSA:2.30.30.40 632 685 3.9E-22 T 29-03-2018 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 SUPERFAMILY SSF47226 3 125 1.7E-33 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 SMART SM01231 305 365 5.8E-19 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 SMART SM00073 3 100 8.2E-38 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Gene3D G3DSA:1.20.120.160 1 143 2.2E-34 T 29-03-2018 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Gene3D G3DSA:3.30.70.1110 176 255 9.6E-25 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 SUPERFAMILY SSF55052 174 255 2.28E-24 T 29-03-2018 IPR015162 CheY binding CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 SMART SM00260 545 685 3.7E-45 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Gene3D G3DSA:2.40.50.180 576 631 9.0E-13 T 29-03-2018 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Gene3D G3DSA:3.30.565.10 367 554 2.4E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Pfam PF01627 Hpt domain 5 100 2.2E-20 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 SMART SM00387 410 553 1.3E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Pfam PF01584 CheW-like domain 558 685 2.3E-28 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 Gene3D G3DSA:1.10.287.560 305 366 5.0E-19 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 SUPERFAMILY SSF47384 306 366 3.3E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 550 8.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 531 8.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09215 93d3891b4cdeac9614697faf887baaf9 686 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 469 8.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS03605 d6bdca1a61e9fd30711e4eb9de81d5cf 400 Pfam PF01551 Peptidase family M23 299 395 1.8E-31 T 29-03-2018 IPR016047 Peptidase M23 CB4_RS03605 d6bdca1a61e9fd30711e4eb9de81d5cf 400 SUPERFAMILY SSF51261 192 399 1.05E-57 T 29-03-2018 IPR011055 Duplicated hybrid motif CB4_RS03605 d6bdca1a61e9fd30711e4eb9de81d5cf 400 Gene3D G3DSA:1.20.5.50 20 131 2.8E-7 T 29-03-2018 CB4_RS03605 d6bdca1a61e9fd30711e4eb9de81d5cf 400 Gene3D G3DSA:2.70.70.10 174 400 1.7E-46 T 29-03-2018 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 SUPERFAMILY SSF52540 160 346 8.33E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 1.5E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 1.5E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 1.5E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 1.5E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 Pfam PF01018 GTP1/OBG 3 157 2.7E-59 T 29-03-2018 IPR006169 GTP1/OBG domain CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 PIRSF PIRSF002401 1 374 3.4E-140 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 327 9.1E-142 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 SUPERFAMILY SSF102741 357 426 3.14E-22 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 357 425 2.1E-26 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 Gene3D G3DSA:2.70.210.12 1 155 3.7E-57 T 29-03-2018 IPR006169 GTP1/OBG domain CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 Pfam PF01926 50S ribosome-binding GTPase 160 283 3.1E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 Gene3D G3DSA:3.40.50.300 158 331 3.2E-35 T 29-03-2018 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 Hamap MF_01454 GTPase Obg [obg]. 1 328 47.725 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 SUPERFAMILY SSF82051 1 157 3.92E-55 T 29-03-2018 IPR006169 GTP1/OBG domain CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 322 5.1E-13 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CB4_RS05875 e7d583f41b8f6c154f1789c41f1e2f39 426 Pfam PF09269 Domain of unknown function (DUF1967) 357 424 2.0E-26 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 SMART SM00100 595 715 4.8E-23 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 SUPERFAMILY SSF51206 588 717 3.54E-33 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 SUPERFAMILY SSF90123 6 316 1.96E-58 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 PRINTS PR00103 cAMP-dependent protein kinase signature 616 630 2.8E-9 T 29-03-2018 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 PRINTS PR00103 cAMP-dependent protein kinase signature 631 645 2.8E-9 T 29-03-2018 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 PRINTS PR00103 cAMP-dependent protein kinase signature 663 672 2.8E-9 T 29-03-2018 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 PRINTS PR00103 cAMP-dependent protein kinase signature 675 686 2.8E-9 T 29-03-2018 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 Gene3D G3DSA:3.40.50.300 327 576 3.7E-78 T 29-03-2018 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 665 682 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 Pfam PF00005 ABC transporter 352 501 2.9E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 Gene3D G3DSA:1.20.1560.10 3 317 6.1E-52 T 29-03-2018 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 SUPERFAMILY SSF52540 329 571 1.08E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 Pfam PF00664 ABC transporter transmembrane region 20 286 2.5E-35 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 SMART SM00382 361 547 2.0E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 Gene3D G3DSA:2.60.120.10 577 719 2.1E-35 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 622 638 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CB4_RS12580 8a4fba815fa0fbe06d99629dd4698fad 719 Pfam PF00027 Cyclic nucleotide-binding domain 614 703 8.5E-21 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS17600 0d89a9c6a8f22eec214aa135db1ca470 328 Gene3D G3DSA:3.10.180.10 1 135 1.1E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS17600 0d89a9c6a8f22eec214aa135db1ca470 328 Gene3D G3DSA:4.10.1270.10 294 328 7.0E-7 T 29-03-2018 CB4_RS17600 0d89a9c6a8f22eec214aa135db1ca470 328 SUPERFAMILY SSF54593 3 271 6.81E-46 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS17600 0d89a9c6a8f22eec214aa135db1ca470 328 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 241 262 - T 29-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CB4_RS17600 0d89a9c6a8f22eec214aa135db1ca470 328 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 5 303 5.1E-122 T 29-03-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type CB4_RS17600 0d89a9c6a8f22eec214aa135db1ca470 328 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 119 2.4E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CB4_RS17600 0d89a9c6a8f22eec214aa135db1ca470 328 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 143 263 2.9E-17 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CB4_RS17600 0d89a9c6a8f22eec214aa135db1ca470 328 Gene3D G3DSA:3.10.180.10 136 293 1.8E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 Pfam PF00672 HAMP domain 185 233 6.5E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 SUPERFAMILY SSF158472 185 235 2.75E-12 T 29-03-2018 CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 SMART SM00304 185 237 4.9E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 SUPERFAMILY SSF47384 221 303 9.81E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 Gene3D G3DSA:1.10.287.130 228 299 1.3E-16 T 29-03-2018 CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 459 8.6E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 SUPERFAMILY SSF55874 294 459 9.3E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 SMART SM00388 238 304 4.1E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 Gene3D G3DSA:3.30.565.10 308 460 1.6E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 7.1E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 7.1E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 7.1E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 7.1E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 SMART SM00387 348 460 2.2E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12500 fd696cb4c4c7db412a4a33a6228b2c23 460 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 303 8.4E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 Gene3D G3DSA:3.40.50.300 812 978 3.5E-25 T 29-03-2018 CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 SUPERFAMILY SSF52540 377 488 4.02E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 SMART SM01058 501 598 1.8E-49 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 SMART SM00490 848 932 1.0E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 Pfam PF00270 DEAD/DEAH box helicase 628 786 2.8E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 42 1164 29.796 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 SUPERFAMILY SSF52540 545 805 1.68E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 Pfam PF00271 Helicase conserved C-terminal domain 832 931 4.4E-16 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 SMART SM00487 622 812 2.1E-34 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 SMART SM00982 1026 1126 1.2E-33 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 SUPERFAMILY SSF141259 492 570 3.27E-26 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 Pfam PF03461 TRCF domain 1028 1118 3.2E-27 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 Pfam PF02559 CarD-like/TRCF domain 502 597 3.8E-32 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 SUPERFAMILY SSF52540 804 1012 6.83E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 Gene3D G3DSA:3.40.50.300 301 797 5.4E-40 T 29-03-2018 CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 SUPERFAMILY SSF52540 14 361 5.05E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 SUPERFAMILY SSF143517 1015 1162 1.02E-33 T 29-03-2018 CB4_RS01470 51c379dd9417c2ad6aeea99d526a321a 1185 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 158 1099 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CB4_RS08245 ec34219865483534b8e1c2ebfba994e3 471 Pfam PF08245 Mur ligase middle domain 118 308 1.6E-31 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS08245 ec34219865483534b8e1c2ebfba994e3 471 SUPERFAMILY SSF53623 104 325 2.09E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS08245 ec34219865483534b8e1c2ebfba994e3 471 Gene3D G3DSA:3.40.50.720 1 102 2.0E-19 T 29-03-2018 CB4_RS08245 ec34219865483534b8e1c2ebfba994e3 471 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 11 467 35.894 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS08245 ec34219865483534b8e1c2ebfba994e3 471 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 12 465 2.2E-133 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS08245 ec34219865483534b8e1c2ebfba994e3 471 SUPERFAMILY SSF51984 7 101 6.02E-17 T 29-03-2018 CB4_RS08245 ec34219865483534b8e1c2ebfba994e3 471 SUPERFAMILY SSF53244 327 467 1.74E-45 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS08245 ec34219865483534b8e1c2ebfba994e3 471 Gene3D G3DSA:3.40.1190.10 103 325 2.6E-54 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS08245 ec34219865483534b8e1c2ebfba994e3 471 Gene3D G3DSA:3.90.190.20 332 466 4.6E-40 T 29-03-2018 CB4_RS08245 ec34219865483534b8e1c2ebfba994e3 471 Pfam PF02875 Mur ligase family, glutamate ligase domain 328 396 1.3E-9 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 Gene3D G3DSA:3.90.1170.30 338 423 7.5E-27 T 29-03-2018 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 PIRSF PIRSF000478 1 431 9.0E-164 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 2.0E-45 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 29-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 Gene3D G3DSA:3.40.1030.10 68 337 7.3E-94 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 346 418 4.0E-24 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 Gene3D G3DSA:1.20.970.10 1 66 1.3E-26 T 29-03-2018 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 SUPERFAMILY SSF54680 332 430 1.44E-26 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 SUPERFAMILY SSF47648 1 69 9.81E-23 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 2.6E-177 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 SMART SM00941 345 418 4.9E-28 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 SUPERFAMILY SSF52418 69 329 1.09E-91 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS04885 8897b61db1271f29c2c1b4ad39d25d2a 431 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 2.9E-24 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CB4_RS18430 e5eccb1a7bf023f725ebd6c5d155d67c 223 SUPERFAMILY SSF46785 6 77 7.81E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18430 e5eccb1a7bf023f725ebd6c5d155d67c 223 SMART SM00345 14 73 7.3E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS18430 e5eccb1a7bf023f725ebd6c5d155d67c 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 2.5E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS18430 e5eccb1a7bf023f725ebd6c5d155d67c 223 Gene3D G3DSA:1.20.120.530 92 222 5.6E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS18430 e5eccb1a7bf023f725ebd6c5d155d67c 223 Gene3D G3DSA:1.10.10.10 5 75 9.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18430 e5eccb1a7bf023f725ebd6c5d155d67c 223 SUPERFAMILY SSF48008 97 221 2.88E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS18430 e5eccb1a7bf023f725ebd6c5d155d67c 223 Pfam PF07729 FCD domain 98 219 2.1E-26 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS18430 e5eccb1a7bf023f725ebd6c5d155d67c 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.4E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS18430 e5eccb1a7bf023f725ebd6c5d155d67c 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.4E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS18430 e5eccb1a7bf023f725ebd6c5d155d67c 223 SMART SM00895 98 220 2.2E-19 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS02040 c855da0fc036790fddb89917c678008d 243 Gene3D G3DSA:2.70.70.10 86 243 1.1E-50 T 29-03-2018 CB4_RS02040 c855da0fc036790fddb89917c678008d 243 SUPERFAMILY SSF51261 87 242 6.28E-57 T 29-03-2018 IPR011055 Duplicated hybrid motif CB4_RS02040 c855da0fc036790fddb89917c678008d 243 Pfam PF01551 Peptidase family M23 143 238 1.5E-35 T 29-03-2018 IPR016047 Peptidase M23 CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 Gene3D G3DSA:3.20.20.70 771 1201 1.1E-99 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 Pfam PF01645 Conserved region in glutamate synthase 803 1156 9.3E-100 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 SUPERFAMILY SSF69336 1225 1490 3.53E-40 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 Gene3D G3DSA:2.160.20.60 1205 1494 1.5E-53 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 Pfam PF04898 Glutamate synthase central domain 446 731 1.3E-64 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 Pfam PF01493 GXGXG motif 1254 1410 8.4E-19 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 SUPERFAMILY SSF56235 20 395 9.26E-80 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 Gene3D G3DSA:3.20.20.70 426 770 1.8E-61 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 Pfam PF00310 Glutamine amidotransferases class-II 20 393 2.1E-57 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 SUPERFAMILY SSF51395 446 1172 1.74E-154 T 29-03-2018 CB4_RS19190 bb423cb42c298705e0192bccca720438 1494 Gene3D G3DSA:3.60.20.10 20 411 2.4E-75 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS17830 c596960429a469363f0dc4ef14e5d22e 376 Pfam PF01266 FAD dependent oxidoreductase 7 351 4.5E-68 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CB4_RS17830 c596960429a469363f0dc4ef14e5d22e 376 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 9 356 1.3E-100 T 29-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CB4_RS17830 c596960429a469363f0dc4ef14e5d22e 376 SUPERFAMILY SSF51905 313 370 6.02E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17830 c596960429a469363f0dc4ef14e5d22e 376 SUPERFAMILY SSF51905 5 226 6.02E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17830 c596960429a469363f0dc4ef14e5d22e 376 SUPERFAMILY SSF54373 226 312 2.62E-14 T 29-03-2018 CB4_RS17830 c596960429a469363f0dc4ef14e5d22e 376 Gene3D G3DSA:3.40.50.720 2 80 1.2E-7 T 29-03-2018 CB4_RS17830 c596960429a469363f0dc4ef14e5d22e 376 Gene3D G3DSA:3.30.9.10 166 312 8.5E-27 T 29-03-2018 CB4_RS17830 c596960429a469363f0dc4ef14e5d22e 376 Gene3D G3DSA:3.30.9.10 94 165 7.2E-7 T 29-03-2018 CB4_RS18235 176c68545ac0bc773146ca5ac2b68b3f 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS18235 176c68545ac0bc773146ca5ac2b68b3f 65 Pfam PF01632 Ribosomal protein L35 2 62 2.8E-28 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS18235 176c68545ac0bc773146ca5ac2b68b3f 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 6.9E-30 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CB4_RS18235 176c68545ac0bc773146ca5ac2b68b3f 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 20.2 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CB4_RS18235 176c68545ac0bc773146ca5ac2b68b3f 65 SUPERFAMILY SSF143034 2 64 1.14E-24 T 29-03-2018 CB4_RS18235 176c68545ac0bc773146ca5ac2b68b3f 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.1E-23 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CB4_RS18235 176c68545ac0bc773146ca5ac2b68b3f 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.1E-23 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CB4_RS18235 176c68545ac0bc773146ca5ac2b68b3f 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.1E-23 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CB4_RS11740 8cf46c2e64ff36ed87c1396e6c1c94e5 172 PIRSF PIRSF037785 1 172 6.0E-61 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CB4_RS11740 8cf46c2e64ff36ed87c1396e6c1c94e5 172 SUPERFAMILY SSF52980 8 170 3.49E-48 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CB4_RS11740 8cf46c2e64ff36ed87c1396e6c1c94e5 172 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 172 55.36 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CB4_RS11740 8cf46c2e64ff36ed87c1396e6c1c94e5 172 Pfam PF03838 Recombination protein U 6 166 2.4E-48 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CB4_RS11740 8cf46c2e64ff36ed87c1396e6c1c94e5 172 Gene3D G3DSA:3.40.1350.10 7 169 1.4E-49 T 29-03-2018 CB4_RS02650 ad099b6c06b946f93f59a3ffbfacb786 248 SMART SM00382 30 215 2.5E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS02650 ad099b6c06b946f93f59a3ffbfacb786 248 Gene3D G3DSA:3.40.50.300 1 241 5.3E-56 T 29-03-2018 CB4_RS02650 ad099b6c06b946f93f59a3ffbfacb786 248 SUPERFAMILY SSF52540 3 228 7.56E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02650 ad099b6c06b946f93f59a3ffbfacb786 248 Pfam PF00005 ABC transporter 22 164 1.9E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS18520 123d157972621c61e5dd2efc6df00b3e 365 SUPERFAMILY SSF56059 111 333 3.89E-17 T 29-03-2018 CB4_RS18520 123d157972621c61e5dd2efc6df00b3e 365 Gene3D G3DSA:3.30.1490.20 132 204 7.8E-8 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS18520 123d157972621c61e5dd2efc6df00b3e 365 Pfam PF14398 YheC/D like ATP-grasp 102 356 9.3E-68 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CB4_RS18520 123d157972621c61e5dd2efc6df00b3e 365 Gene3D G3DSA:3.30.470.20 205 339 4.4E-14 T 29-03-2018 CB4_RS03600 3fa5c15de046c731f2ba26dc2c433e6e 297 PIRSF PIRSF003097 1 297 1.1E-89 T 29-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CB4_RS10575 a4644e5699131fc7384cdd1e4920c572 248 Gene3D G3DSA:3.90.1580.10 66 242 1.8E-46 T 29-03-2018 CB4_RS10575 a4644e5699131fc7384cdd1e4920c572 248 Gene3D G3DSA:3.90.1580.10 6 65 0.018 T 29-03-2018 CB4_RS10575 a4644e5699131fc7384cdd1e4920c572 248 Pfam PF03781 Sulfatase-modifying factor enzyme 1 51 245 1.4E-37 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CB4_RS10575 a4644e5699131fc7384cdd1e4920c572 248 SUPERFAMILY SSF56436 13 106 2.83E-51 T 29-03-2018 IPR016187 C-type lectin fold CB4_RS10575 a4644e5699131fc7384cdd1e4920c572 248 SUPERFAMILY SSF56436 133 246 2.83E-51 T 29-03-2018 IPR016187 C-type lectin fold CB4_RS06240 794d2475b8895849f1f7e9c16768e934 253 SUPERFAMILY SSF88713 40 234 3.61E-49 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS06240 794d2475b8895849f1f7e9c16768e934 253 Gene3D G3DSA:3.20.20.370 31 242 1.1E-42 T 29-03-2018 CB4_RS06240 794d2475b8895849f1f7e9c16768e934 253 Pfam PF01522 Polysaccharide deacetylase 38 140 9.5E-28 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS06810 a138ad7e078692b8858bcb851f36ca39 474 Pfam PF05954 Phage late control gene D protein (GPD) 75 167 2.7E-8 T 29-03-2018 CB4_RS06810 a138ad7e078692b8858bcb851f36ca39 474 Gene3D G3DSA:3.55.50.10 100 178 1.8E-10 T 29-03-2018 CB4_RS06810 a138ad7e078692b8858bcb851f36ca39 474 SUPERFAMILY SSF69279 20 169 2.0E-22 T 29-03-2018 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 Gene3D G3DSA:2.30.22.10 132 188 3.6E-20 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 Pfam PF01025 GrpE 31 187 2.0E-53 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 PRINTS PR00773 GrpE protein signature 58 74 1.4E-28 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 PRINTS PR00773 GrpE protein signature 140 155 1.4E-28 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 PRINTS PR00773 GrpE protein signature 167 186 1.4E-28 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 PRINTS PR00773 GrpE protein signature 86 101 1.4E-28 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 Hamap MF_01151 Protein GrpE [grpE]. 7 188 20.345 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 Gene3D G3DSA:3.90.20.20 6 130 6.6E-25 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 ProSitePatterns PS01071 grpE protein signature. 143 186 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 SUPERFAMILY SSF58014 39 132 5.89E-26 T 29-03-2018 CB4_RS06680 bb6bb501c1dca621469e569f61a98ba3 188 SUPERFAMILY SSF51064 134 187 4.45E-18 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CB4_RS06060 1e0dd0c9351c8056a52501f23f6ce128 376 Gene3D G3DSA:3.90.1150.10 264 376 4.2E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS06060 1e0dd0c9351c8056a52501f23f6ce128 376 Pfam PF00266 Aminotransferase class-V 4 364 1.8E-80 T 29-03-2018 IPR000192 Aminotransferase class V domain CB4_RS06060 1e0dd0c9351c8056a52501f23f6ce128 376 SUPERFAMILY SSF53383 2 375 6.19E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS06060 1e0dd0c9351c8056a52501f23f6ce128 376 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CB4_RS06060 1e0dd0c9351c8056a52501f23f6ce128 376 Gene3D G3DSA:3.40.640.10 12 256 1.2E-59 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS06060 1e0dd0c9351c8056a52501f23f6ce128 376 PIRSF PIRSF005572 1 376 4.3E-123 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Gene3D G3DSA:2.60.40.1080 413 501 4.7E-25 T 29-03-2018 CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Pfam PF12733 Cadherin-like beta sandwich domain 334 412 2.2E-15 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 SMART SM00135 229 270 0.073 T 29-03-2018 IPR000033 LDLR class B repeat CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 SMART SM00135 184 225 38.0 T 29-03-2018 IPR000033 LDLR class B repeat CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 SMART SM00135 41 85 92.0 T 29-03-2018 IPR000033 LDLR class B repeat CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 SMART SM00635 417 495 3.4E-21 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Gene3D G3DSA:2.120.10.30 141 224 2.0E-16 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Pfam PF00395 S-layer homology domain 883 926 2.1E-13 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Pfam PF00395 S-layer homology domain 825 866 2.9E-13 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Pfam PF00395 S-layer homology domain 765 805 2.0E-15 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 SUPERFAMILY SSF49373 416 498 3.06E-20 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Gene3D G3DSA:2.120.10.30 225 401 9.5E-14 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Pfam PF02368 Bacterial Ig-like domain (group 2) 421 495 3.7E-16 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Gene3D G3DSA:2.120.10.30 34 140 1.7E-14 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Pfam PF01436 NHL repeat 283 309 1.2E-5 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 SUPERFAMILY SSF101898 49 310 1.67E-53 T 29-03-2018 CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 58 179 6.5E-7 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CB4_RS18025 67a73941c2864f3a48355f0effd3ddf8 937 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 190 273 2.5E-10 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CB4_RS13630 6e6fe594fc411274b8e46805fb4e99b6 455 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 439 1.7E-158 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS13630 6e6fe594fc411274b8e46805fb4e99b6 455 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS13630 6e6fe594fc411274b8e46805fb4e99b6 455 PRINTS PR00175 Sodium/alanine symporter signature 92 114 2.4E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS13630 6e6fe594fc411274b8e46805fb4e99b6 455 PRINTS PR00175 Sodium/alanine symporter signature 183 201 2.4E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS13630 6e6fe594fc411274b8e46805fb4e99b6 455 PRINTS PR00175 Sodium/alanine symporter signature 306 324 2.4E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS13630 6e6fe594fc411274b8e46805fb4e99b6 455 PRINTS PR00175 Sodium/alanine symporter signature 409 429 2.4E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS13630 6e6fe594fc411274b8e46805fb4e99b6 455 PRINTS PR00175 Sodium/alanine symporter signature 350 372 2.4E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS13630 6e6fe594fc411274b8e46805fb4e99b6 455 PRINTS PR00175 Sodium/alanine symporter signature 211 230 2.4E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS13630 6e6fe594fc411274b8e46805fb4e99b6 455 Pfam PF01235 Sodium:alanine symporter family 56 448 2.0E-147 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CB4_RS01120 21bf95361fe86237c238e16e7c33f2b4 84 SUPERFAMILY SSF55315 6 82 5.62E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CB4_RS01120 21bf95361fe86237c238e16e7c33f2b4 84 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 83 4.5E-14 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CB4_RS01120 21bf95361fe86237c238e16e7c33f2b4 84 Gene3D G3DSA:3.30.1330.30 2 84 6.3E-17 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CB4_RS02530 127cbad12ebd6faab66f9a57567dab0a 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 42 174 1.1E-17 T 29-03-2018 IPR023214 HAD-like domain CB4_RS02530 127cbad12ebd6faab66f9a57567dab0a 210 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 84 169 6.3E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS02530 127cbad12ebd6faab66f9a57567dab0a 210 SUPERFAMILY SSF56784 1 204 1.17E-25 T 29-03-2018 IPR023214 HAD-like domain CB4_RS02530 127cbad12ebd6faab66f9a57567dab0a 210 Gene3D G3DSA:3.40.50.1000 58 208 1.1E-22 T 29-03-2018 IPR023214 HAD-like domain CB4_RS10345 38fbd0bee1304cb0c752bcbfe81ef746 223 SMART SM00850 123 222 4.9E-31 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CB4_RS10345 38fbd0bee1304cb0c752bcbfe81ef746 223 Gene3D G3DSA:2.20.25.10 184 222 1.8E-11 T 29-03-2018 CB4_RS10345 38fbd0bee1304cb0c752bcbfe81ef746 223 Pfam PF04397 LytTr DNA-binding domain 123 221 1.4E-25 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CB4_RS10345 38fbd0bee1304cb0c752bcbfe81ef746 223 Gene3D G3DSA:2.40.50.40 114 182 1.2E-16 T 29-03-2018 CB4_RS14200 8b89b3c924b50434f9cf511835398d6c 340 SMART SM00930 262 337 8.3E-24 T 29-03-2018 IPR018449 NIL domain CB4_RS14200 8b89b3c924b50434f9cf511835398d6c 340 SUPERFAMILY SSF55021 248 340 9.96E-23 T 29-03-2018 CB4_RS14200 8b89b3c924b50434f9cf511835398d6c 340 SMART SM00382 30 226 1.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS14200 8b89b3c924b50434f9cf511835398d6c 340 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS14200 8b89b3c924b50434f9cf511835398d6c 340 Pfam PF09383 NIL domain 264 336 1.4E-20 T 29-03-2018 IPR018449 NIL domain CB4_RS14200 8b89b3c924b50434f9cf511835398d6c 340 SUPERFAMILY SSF52540 1 240 1.16E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14200 8b89b3c924b50434f9cf511835398d6c 340 Pfam PF00005 ABC transporter 22 169 3.6E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS14200 8b89b3c924b50434f9cf511835398d6c 340 Gene3D G3DSA:3.40.50.300 1 252 1.1E-78 T 29-03-2018 CB4_RS14200 8b89b3c924b50434f9cf511835398d6c 340 Gene3D G3DSA:3.30.70.260 253 340 3.7E-25 T 29-03-2018 CB4_RS20740 022742519fdd5fecef808d8df0008da1 136 Pfam PF02082 Transcriptional regulator 2 80 2.3E-21 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CB4_RS20740 022742519fdd5fecef808d8df0008da1 136 Gene3D G3DSA:1.10.10.10 1 135 1.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS20740 022742519fdd5fecef808d8df0008da1 136 SUPERFAMILY SSF46785 5 131 1.29E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12670 3dfc74c9fc9212a0a8b1909a55b19312 123 Pfam PF01022 Bacterial regulatory protein, arsR family 44 90 6.5E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12670 3dfc74c9fc9212a0a8b1909a55b19312 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 2.6E-23 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12670 3dfc74c9fc9212a0a8b1909a55b19312 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 2.6E-23 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12670 3dfc74c9fc9212a0a8b1909a55b19312 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 2.6E-23 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12670 3dfc74c9fc9212a0a8b1909a55b19312 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 70 2.6E-23 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12670 3dfc74c9fc9212a0a8b1909a55b19312 123 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 61 79 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CB4_RS12670 3dfc74c9fc9212a0a8b1909a55b19312 123 Gene3D G3DSA:1.10.10.10 4 122 2.9E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12670 3dfc74c9fc9212a0a8b1909a55b19312 123 SUPERFAMILY SSF46785 23 114 1.73E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12670 3dfc74c9fc9212a0a8b1909a55b19312 123 SMART SM00418 37 116 1.4E-30 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS01380 e13a47c356b40c5a5b11427c3c793d34 255 SUPERFAMILY SSF53067 1 122 2.16E-38 T 29-03-2018 CB4_RS01380 e13a47c356b40c5a5b11427c3c793d34 255 SUPERFAMILY SSF53067 124 253 1.43E-39 T 29-03-2018 CB4_RS01380 e13a47c356b40c5a5b11427c3c793d34 255 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 37.52 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CB4_RS01380 e13a47c356b40c5a5b11427c3c793d34 255 Gene3D G3DSA:3.30.420.40 89 255 9.4E-62 T 29-03-2018 CB4_RS01380 e13a47c356b40c5a5b11427c3c793d34 255 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 249 6.3E-81 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CB4_RS01380 e13a47c356b40c5a5b11427c3c793d34 255 Pfam PF03309 Type III pantothenate kinase 3 206 5.4E-72 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CB4_RS07185 0f7baeb4ef02ab170af01f682aeca05c 371 Gene3D G3DSA:3.30.70.120 132 224 5.6E-40 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CB4_RS07185 0f7baeb4ef02ab170af01f682aeca05c 371 Gene3D G3DSA:3.40.1390.30 225 359 1.4E-21 T 29-03-2018 CB4_RS07185 0f7baeb4ef02ab170af01f682aeca05c 371 PIRSF PIRSF037489 2 371 3.7E-155 T 29-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CB4_RS07185 0f7baeb4ef02ab170af01f682aeca05c 371 Gene3D G3DSA:3.40.1390.30 2 124 2.1E-35 T 29-03-2018 CB4_RS07185 0f7baeb4ef02ab170af01f682aeca05c 371 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 350 3.2E-80 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CB4_RS07185 0f7baeb4ef02ab170af01f682aeca05c 371 SUPERFAMILY SSF102705 5 370 9.03E-131 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CB4_RS07185 0f7baeb4ef02ab170af01f682aeca05c 371 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 3 367 1.3E-82 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CB4_RS18565 2785c6ef045c09d2e3c2dd9b2c57b0ad 240 Pfam PF14256 YwiC-like protein 5 131 3.2E-38 T 29-03-2018 IPR025576 YwiC-like protein CB4_RS02680 a9d524f5e15956b80d76f9d2e12e5ff3 614 Pfam PF13537 Glutamine amidotransferase domain 48 169 6.9E-44 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CB4_RS02680 a9d524f5e15956b80d76f9d2e12e5ff3 614 PIRSF PIRSF001589 1 613 4.7E-136 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CB4_RS02680 a9d524f5e15956b80d76f9d2e12e5ff3 614 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 534 1.2E-156 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CB4_RS02680 a9d524f5e15956b80d76f9d2e12e5ff3 614 Pfam PF00733 Asparagine synthase 242 607 4.8E-94 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CB4_RS02680 a9d524f5e15956b80d76f9d2e12e5ff3 614 Gene3D G3DSA:3.60.20.10 1 223 5.6E-52 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS02680 a9d524f5e15956b80d76f9d2e12e5ff3 614 SUPERFAMILY SSF52402 454 579 4.45E-72 T 29-03-2018 CB4_RS02680 a9d524f5e15956b80d76f9d2e12e5ff3 614 SUPERFAMILY SSF52402 230 396 4.45E-72 T 29-03-2018 CB4_RS02680 a9d524f5e15956b80d76f9d2e12e5ff3 614 Gene3D G3DSA:3.40.50.620 224 613 7.7E-68 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS02680 a9d524f5e15956b80d76f9d2e12e5ff3 614 SUPERFAMILY SSF56235 1 226 1.12E-60 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 Gene3D G3DSA:3.30.450.20 33 181 2.0E-22 T 29-03-2018 CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 SMART SM00304 300 352 4.9E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 Pfam PF02743 Cache domain 40 262 5.0E-29 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 Gene3D G3DSA:1.10.287.950 409 657 2.8E-54 T 29-03-2018 CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 SUPERFAMILY SSF58104 320 354 2.62E-73 T 29-03-2018 CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 SUPERFAMILY SSF58104 387 656 2.62E-73 T 29-03-2018 CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 Pfam PF00672 HAMP domain 300 348 3.9E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 SMART SM00283 381 656 2.5E-87 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 428 610 2.3E-44 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 Gene3D G3DSA:1.10.287.950 298 408 1.5E-6 T 29-03-2018 CB4_RS10930 3db4861701138de6185eefd3dc4699a4 657 SUPERFAMILY SSF103190 98 190 4.79E-11 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS10540 19c00366787a54ac1be3c92e63c50596 380 Pfam PF01170 Putative RNA methylase family UPF0020 163 367 3.3E-55 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS10540 19c00366787a54ac1be3c92e63c50596 380 SUPERFAMILY SSF53335 255 373 4.22E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS10540 19c00366787a54ac1be3c92e63c50596 380 SUPERFAMILY SSF53335 144 218 4.22E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS10540 19c00366787a54ac1be3c92e63c50596 380 Pfam PF02926 THUMP domain 15 155 2.4E-15 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CB4_RS10540 19c00366787a54ac1be3c92e63c50596 380 SMART SM00981 58 155 1.7E-10 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CB4_RS10540 19c00366787a54ac1be3c92e63c50596 380 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 196 207 - T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS10540 19c00366787a54ac1be3c92e63c50596 380 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CB4_RS10540 19c00366787a54ac1be3c92e63c50596 380 Gene3D G3DSA:3.40.50.150 161 379 5.0E-32 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 SUPERFAMILY SSF50249 14 112 5.08E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 PRINTS PR00681 Ribosomal protein S1 signature 108 124 5.9E-55 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 PRINTS PR00681 Ribosomal protein S1 signature 328 346 5.9E-55 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 PRINTS PR00681 Ribosomal protein S1 signature 154 174 5.9E-55 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 PRINTS PR00681 Ribosomal protein S1 signature 211 232 5.9E-55 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 PRINTS PR00681 Ribosomal protein S1 signature 36 50 5.9E-55 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 PRINTS PR00681 Ribosomal protein S1 signature 289 308 5.9E-55 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 PRINTS PR00681 Ribosomal protein S1 signature 18 36 5.9E-55 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 PRINTS PR00681 Ribosomal protein S1 signature 84 103 5.9E-55 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 PRINTS PR00681 Ribosomal protein S1 signature 125 142 5.9E-55 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 SUPERFAMILY SSF50249 90 174 8.58E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 Pfam PF00575 S1 RNA binding domain 273 345 6.3E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 Pfam PF00575 S1 RNA binding domain 15 87 2.0E-14 T 29-03-2018 IPR003029 S1 domain GO:0003676 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 Pfam PF00575 S1 RNA binding domain 101 170 3.2E-17 T 29-03-2018 IPR003029 S1 domain GO:0003676 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 Pfam PF00575 S1 RNA binding domain 189 259 7.4E-27 T 29-03-2018 IPR003029 S1 domain GO:0003676 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 SMART SM00316 274 345 1.7E-23 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 SMART SM00316 189 259 1.0E-29 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 SMART SM00316 103 170 4.1E-13 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 SMART SM00316 16 87 2.1E-16 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 SUPERFAMILY SSF50249 259 349 5.22E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 Gene3D G3DSA:2.40.50.140 276 372 6.2E-24 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 Gene3D G3DSA:2.40.50.140 11 93 6.1E-17 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 Gene3D G3DSA:2.40.50.140 183 264 1.6E-28 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 Gene3D G3DSA:2.40.50.140 98 176 2.2E-15 T 29-03-2018 CB4_RS15255 e21dd550d42c20756a3c9a9adfa00cca 388 SUPERFAMILY SSF50249 189 272 2.72E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS02665 15447593d13a146f002f5d548305ba40 69 Pfam PF13518 Helix-turn-helix domain 25 63 1.3E-7 T 29-03-2018 CB4_RS02665 15447593d13a146f002f5d548305ba40 69 SUPERFAMILY SSF48295 18 66 7.32E-10 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CB4_RS02665 15447593d13a146f002f5d548305ba40 69 Gene3D G3DSA:1.10.10.10 4 67 5.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 Gene3D G3DSA:3.40.1110.10 291 543 1.3E-56 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 SUPERFAMILY SSF56784 500 752 4.21E-67 T 29-03-2018 IPR023214 HAD-like domain CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 SUPERFAMILY SSF56784 326 346 4.21E-67 T 29-03-2018 IPR023214 HAD-like domain CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 SUPERFAMILY SSF81653 118 228 9.55E-32 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 Pfam PF00689 Cation transporting ATPase, C-terminus 731 899 5.6E-50 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 SUPERFAMILY SSF81665 697 895 1.57E-130 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 SUPERFAMILY SSF81665 229 322 1.57E-130 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 SUPERFAMILY SSF81665 7 118 1.57E-130 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 SMART SM00831 6 80 4.4E-24 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 Gene3D G3DSA:1.20.1110.10 668 909 2.9E-72 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 184 7.9E-19 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 215 349 3.3E-28 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 615 737 1.4E-36 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 567 577 3.5E-40 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 647 666 3.5E-40 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 3.5E-40 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 671 683 3.5E-40 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 179 3.5E-40 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 556 3.5E-40 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 Gene3D G3DSA:2.70.150.10 16 229 3.9E-50 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 330 336 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 Pfam PF00690 Cation transporter/ATPase, N-terminus 7 75 4.5E-18 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 Pfam PF00702 haloacid dehalogenase-like hydrolase 326 661 1.2E-25 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 SUPERFAMILY SSF81660 335 549 1.22E-61 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 Pfam PF00122 E1-E2 ATPase 114 307 2.3E-53 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 470 488 2.0E-16 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 81 101 2.0E-16 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 321 342 2.0E-16 T 29-03-2018 CB4_RS08445 a06d1193e60964047e1442c7a7ceb53f 914 Gene3D G3DSA:3.40.50.1000 544 667 2.1E-24 T 29-03-2018 IPR023214 HAD-like domain CB4_RS13920 3409989e1199aaa62f60299418bd94a1 500 Pfam PF13520 Amino acid permease 10 475 1.0E-28 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS13920 3409989e1199aaa62f60299418bd94a1 500 PIRSF PIRSF006060 2 499 1.3E-46 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS02300 c546794d4d3582ffbd22c2cff3b496c5 106 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 12 100 2.2E-25 T 29-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 CB4_RS02300 c546794d4d3582ffbd22c2cff3b496c5 106 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 19 92 1.6E-12 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CB4_RS03715 6f108ffa747187ed2897cacf23a01537 137 Pfam PF01037 Lrp/AsnC ligand binding domain 68 123 9.4E-11 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CB4_RS03715 6f108ffa747187ed2897cacf23a01537 137 SUPERFAMILY SSF54909 64 137 6.57E-16 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CB4_RS03715 6f108ffa747187ed2897cacf23a01537 137 Gene3D G3DSA:3.30.70.920 52 137 7.3E-18 T 29-03-2018 CB4_RS03715 6f108ffa747187ed2897cacf23a01537 137 SMART SM00344 2 108 1.8E-36 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CB4_RS03715 6f108ffa747187ed2897cacf23a01537 137 SUPERFAMILY SSF46785 1 61 1.68E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03715 6f108ffa747187ed2897cacf23a01537 137 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 9.7E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS03715 6f108ffa747187ed2897cacf23a01537 137 Gene3D G3DSA:1.10.10.10 2 51 5.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03715 6f108ffa747187ed2897cacf23a01537 137 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 3.6E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS03715 6f108ffa747187ed2897cacf23a01537 137 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 3.6E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS03715 6f108ffa747187ed2897cacf23a01537 137 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 3.6E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 Pfam PF02574 Homocysteine S-methyltransferase 21 310 7.4E-76 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 Pfam PF02607 B12 binding domain 632 704 2.1E-23 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 PIRSF PIRSF000381 5 1151 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 SUPERFAMILY SSF51717 342 606 1.31E-80 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 Gene3D G3DSA:3.20.20.330 7 322 2.0E-101 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 SUPERFAMILY SSF47644 625 710 3.53E-24 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 SUPERFAMILY SSF52242 713 846 3.53E-39 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 Pfam PF02310 B12 binding domain 717 830 7.4E-21 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 TIGRFAM TIGR02082 metH: methionine synthase 17 1149 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 903 1149 8.5E-59 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 SUPERFAMILY SSF56507 877 1150 4.32E-88 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 Gene3D G3DSA:1.10.1240.10 621 704 4.7E-30 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 Gene3D G3DSA:3.20.20.20 330 620 3.4E-52 T 29-03-2018 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 Pfam PF00809 Pterin binding enzyme 345 578 2.0E-41 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 Gene3D G3DSA:3.10.196.10 931 1151 1.6E-62 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 SUPERFAMILY SSF82282 12 384 9.68E-114 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 Gene3D G3DSA:3.40.50.280 705 859 1.8E-49 T 29-03-2018 CB4_RS04030 9342e6e88ca999e89a47efd93e280c0a 1151 SMART SM01018 629 711 8.5E-39 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS17285 b65fc21c5ebe824fd22d17d5fe914eed 518 Pfam PF17159 Membrane-associated sensor domain 40 266 3.7E-58 T 29-03-2018 IPR033425 Membrane-associated sensor domain MASE3 CB4_RS17285 b65fc21c5ebe824fd22d17d5fe914eed 518 Gene3D G3DSA:3.30.565.10 366 508 1.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS17285 b65fc21c5ebe824fd22d17d5fe914eed 518 SMART SM00387 407 503 2.4E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS17285 b65fc21c5ebe824fd22d17d5fe914eed 518 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 409 501 3.2E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS17285 b65fc21c5ebe824fd22d17d5fe914eed 518 SUPERFAMILY SSF55874 372 500 5.24E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS17285 b65fc21c5ebe824fd22d17d5fe914eed 518 Pfam PF07730 Histidine kinase 304 369 3.7E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CB4_RS02750 167dc618c8b2be25c7cc607717e2d4fb 708 Gene3D G3DSA:1.10.1060.10 253 422 4.9E-32 T 29-03-2018 CB4_RS02750 167dc618c8b2be25c7cc607717e2d4fb 708 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 389 400 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS02750 167dc618c8b2be25c7cc607717e2d4fb 708 Pfam PF13183 4Fe-4S dicluster domain 282 402 1.7E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS02750 167dc618c8b2be25c7cc607717e2d4fb 708 Gene3D G3DSA:1.20.950.20 5 241 2.7E-43 T 29-03-2018 CB4_RS02750 167dc618c8b2be25c7cc607717e2d4fb 708 SUPERFAMILY SSF46548 268 321 2.79E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CB4_RS02750 167dc618c8b2be25c7cc607717e2d4fb 708 SUPERFAMILY SSF46548 371 418 2.79E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CB4_RS02750 167dc618c8b2be25c7cc607717e2d4fb 708 Pfam PF02754 Cysteine-rich domain 480 555 5.7E-5 T 29-03-2018 IPR004017 Cysteine-rich domain CB4_RS02750 167dc618c8b2be25c7cc607717e2d4fb 708 Pfam PF02754 Cysteine-rich domain 595 682 1.4E-15 T 29-03-2018 IPR004017 Cysteine-rich domain CB4_RS02750 167dc618c8b2be25c7cc607717e2d4fb 708 SUPERFAMILY SSF103501 7 242 2.88E-11 T 29-03-2018 IPR023234 NarG-like domain CB4_RS08490 a9bd1feef4c4d3c7ca096d54aae119cf 311 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 126 149 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS08490 a9bd1feef4c4d3c7ca096d54aae119cf 311 Pfam PF00551 Formyl transferase 2 173 2.8E-40 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS08490 a9bd1feef4c4d3c7ca096d54aae119cf 311 Gene3D G3DSA:3.10.25.10 200 308 3.2E-31 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS08490 a9bd1feef4c4d3c7ca096d54aae119cf 311 Gene3D G3DSA:3.40.50.170 1 199 1.5E-66 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS08490 a9bd1feef4c4d3c7ca096d54aae119cf 311 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 298 34.947 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CB4_RS08490 a9bd1feef4c4d3c7ca096d54aae119cf 311 SUPERFAMILY SSF53328 1 199 1.96E-64 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS08490 a9bd1feef4c4d3c7ca096d54aae119cf 311 SUPERFAMILY SSF50486 198 297 5.34E-32 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CB4_RS08490 a9bd1feef4c4d3c7ca096d54aae119cf 311 Pfam PF02911 Formyl transferase, C-terminal domain 197 295 3.7E-29 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS08490 a9bd1feef4c4d3c7ca096d54aae119cf 311 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 296 5.7E-105 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 Gene3D G3DSA:1.10.287.130 128 197 1.4E-11 T 29-03-2018 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 248 357 2.9E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 SUPERFAMILY SSF55874 192 357 2.36E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 SUPERFAMILY SSF47384 122 202 6.87E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 SMART SM00387 247 358 3.4E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 SMART SM00388 138 202 1.2E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 Pfam PF00512 His Kinase A (phospho-acceptor) domain 140 201 1.5E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 SUPERFAMILY SSF158472 86 134 1.28E-9 T 29-03-2018 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 Gene3D G3DSA:3.30.565.10 206 358 1.5E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 312 1.1E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 337 1.1E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 1.1E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 356 1.1E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 SMART SM00304 85 137 2.2E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS12480 7a4160472a87839922aea59475eaee2d 358 Pfam PF00672 HAMP domain 85 133 2.9E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS17660 8a3e24a410ba9421eaca56d2328f6604 65 SUPERFAMILY SSF46955 8 55 7.78E-14 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS17660 8a3e24a410ba9421eaca56d2328f6604 65 Pfam PF13411 MerR HTH family regulatory protein 8 55 1.3E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS17660 8a3e24a410ba9421eaca56d2328f6604 65 SMART SM00422 8 65 2.5E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS17660 8a3e24a410ba9421eaca56d2328f6604 65 Gene3D G3DSA:1.10.1660.10 2 63 5.9E-17 T 29-03-2018 CB4_RS19505 84e2491aaf72667f943c08f240043115 391 Pfam PF02655 ATP-grasp domain 115 284 4.2E-13 T 29-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 CB4_RS19505 84e2491aaf72667f943c08f240043115 391 Gene3D G3DSA:3.40.50.20 3 117 6.8E-5 T 29-03-2018 CB4_RS19505 84e2491aaf72667f943c08f240043115 391 Gene3D G3DSA:3.30.470.20 118 371 1.6E-34 T 29-03-2018 CB4_RS19505 84e2491aaf72667f943c08f240043115 391 SUPERFAMILY SSF56059 114 316 3.05E-33 T 29-03-2018 CB4_RS11970 17dc438039484860217a913a7211044b 389 SUPERFAMILY SSF103473 3 379 3.79E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS11970 17dc438039484860217a913a7211044b 389 Gene3D G3DSA:1.20.1250.20 195 388 8.8E-23 T 29-03-2018 CB4_RS11970 17dc438039484860217a913a7211044b 389 PRINTS PR01035 Tetracycline resistance protein signature 131 153 9.4E-34 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS11970 17dc438039484860217a913a7211044b 389 PRINTS PR01035 Tetracycline resistance protein signature 159 179 9.4E-34 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS11970 17dc438039484860217a913a7211044b 389 PRINTS PR01035 Tetracycline resistance protein signature 242 262 9.4E-34 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS11970 17dc438039484860217a913a7211044b 389 PRINTS PR01035 Tetracycline resistance protein signature 270 291 9.4E-34 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS11970 17dc438039484860217a913a7211044b 389 PRINTS PR01035 Tetracycline resistance protein signature 73 97 9.4E-34 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS11970 17dc438039484860217a913a7211044b 389 PRINTS PR01035 Tetracycline resistance protein signature 330 353 9.4E-34 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS11970 17dc438039484860217a913a7211044b 389 PRINTS PR01035 Tetracycline resistance protein signature 16 32 9.4E-34 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS11970 17dc438039484860217a913a7211044b 389 Gene3D G3DSA:1.20.1250.20 2 194 1.7E-45 T 29-03-2018 CB4_RS11970 17dc438039484860217a913a7211044b 389 Pfam PF07690 Major Facilitator Superfamily 10 323 8.4E-56 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS14795 8c94b91a39bdb3efbd2517369e980958 244 Pfam PF13500 AAA domain 5 216 4.5E-47 T 29-03-2018 CB4_RS14795 8c94b91a39bdb3efbd2517369e980958 244 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 3 217 29.258 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CB4_RS14795 8c94b91a39bdb3efbd2517369e980958 244 SUPERFAMILY SSF52540 1 218 2.15E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14795 8c94b91a39bdb3efbd2517369e980958 244 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 7 181 1.9E-43 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CB4_RS14795 8c94b91a39bdb3efbd2517369e980958 244 PIRSF PIRSF006755 2 238 4.7E-69 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CB4_RS14795 8c94b91a39bdb3efbd2517369e980958 244 Gene3D G3DSA:3.40.50.300 1 219 1.9E-60 T 29-03-2018 CB4_RS13265 012f168798c246a86a11eddc342717e1 160 SMART SM00347 31 130 8.3E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS13265 012f168798c246a86a11eddc342717e1 160 Gene3D G3DSA:1.10.10.10 2 152 5.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13265 012f168798c246a86a11eddc342717e1 160 Pfam PF13463 Winged helix DNA-binding domain 41 104 1.5E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS13265 012f168798c246a86a11eddc342717e1 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 104 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CB4_RS13265 012f168798c246a86a11eddc342717e1 160 SUPERFAMILY SSF46785 10 150 6.34E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16040 8d15274695db09e464dbfae5f5d34b34 371 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 356 8.7E-126 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CB4_RS16040 8d15274695db09e464dbfae5f5d34b34 371 PIRSF PIRSF006769 1 362 1.1E-139 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CB4_RS16040 8d15274695db09e464dbfae5f5d34b34 371 Gene3D G3DSA:3.40.430.10 125 369 6.1E-81 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CB4_RS16040 8d15274695db09e464dbfae5f5d34b34 371 SUPERFAMILY SSF53597 145 360 2.13E-62 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CB4_RS16040 8d15274695db09e464dbfae5f5d34b34 371 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 88 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CB4_RS16040 8d15274695db09e464dbfae5f5d34b34 371 Pfam PF01872 RibD C-terminal domain 147 356 3.0E-56 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CB4_RS16040 8d15274695db09e464dbfae5f5d34b34 371 SUPERFAMILY SSF53927 3 145 2.07E-47 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CB4_RS16040 8d15274695db09e464dbfae5f5d34b34 371 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 145 358 3.2E-69 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CB4_RS16040 8d15274695db09e464dbfae5f5d34b34 371 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 99 3.8E-19 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CB4_RS16040 8d15274695db09e464dbfae5f5d34b34 371 Gene3D G3DSA:3.40.140.10 1 124 2.8E-33 T 29-03-2018 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 298 313 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 Gene3D G3DSA:3.30.65.10 630 661 1.1E-6 T 29-03-2018 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 Gene3D G3DSA:1.10.460.10 158 335 2.4E-43 T 29-03-2018 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 Pfam PF01131 DNA topoisomerase 152 566 1.6E-126 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 Gene3D G3DSA:3.40.50.140 2 153 3.8E-42 T 29-03-2018 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 8.2E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 495 509 8.2E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 387 403 8.2E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 304 313 8.2E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 8.2E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 704 3.9E-199 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 Gene3D G3DSA:2.70.20.10 351 471 1.1E-27 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 Pfam PF01751 Toprim domain 4 132 9.2E-14 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS13850 691076913314a0d6262d7841016ddd69 713 SUPERFAMILY SSF56712 2 580 8.37E-177 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CB4_RS13850 691076913314a0d6262d7841016ddd69 713 SMART SM00437 261 532 2.2E-78 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 SMART SM00493 2 125 3.1E-22 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS13850 691076913314a0d6262d7841016ddd69 713 Gene3D G3DSA:1.10.460.10 472 629 2.8E-36 T 29-03-2018 CB4_RS13850 691076913314a0d6262d7841016ddd69 713 SMART SM00436 125 215 5.2E-32 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CB4_RS18330 83cbff3e55cccd68fbc6cfeb29f64d52 467 SMART SM00849 13 250 1.7E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS18330 83cbff3e55cccd68fbc6cfeb29f64d52 467 SMART SM01027 255 380 2.3E-52 T 29-03-2018 IPR022712 Beta-Casp domain CB4_RS18330 83cbff3e55cccd68fbc6cfeb29f64d52 467 Pfam PF10996 Beta-Casp domain 255 380 2.0E-26 T 29-03-2018 IPR022712 Beta-Casp domain CB4_RS18330 83cbff3e55cccd68fbc6cfeb29f64d52 467 Gene3D G3DSA:3.60.15.10 3 271 2.6E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS18330 83cbff3e55cccd68fbc6cfeb29f64d52 467 SUPERFAMILY SSF56281 1 465 1.83E-132 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS18330 83cbff3e55cccd68fbc6cfeb29f64d52 467 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 394 457 1.0E-14 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CB4_RS18330 83cbff3e55cccd68fbc6cfeb29f64d52 467 Pfam PF00753 Metallo-beta-lactamase superfamily 11 75 4.8E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS16080 c92aba2e3d6a9833b95413af897248b4 131 Pfam PF13181 Tetratricopeptide repeat 4 24 0.057 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS16080 c92aba2e3d6a9833b95413af897248b4 131 SUPERFAMILY SSF48452 2 110 1.31E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS16080 c92aba2e3d6a9833b95413af897248b4 131 Gene3D G3DSA:1.25.40.10 1 124 2.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS01925 245c2cdab58181326305ede7c5700eff 247 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 55 237 4.1E-69 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CB4_RS01925 245c2cdab58181326305ede7c5700eff 247 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 240 28.005 T 29-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CB4_RS01925 245c2cdab58181326305ede7c5700eff 247 PRINTS PR01900 YidC translocation/secretion protein signature 192 216 8.1E-5 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CB4_RS01925 245c2cdab58181326305ede7c5700eff 247 PRINTS PR01900 YidC translocation/secretion protein signature 168 183 8.1E-5 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CB4_RS01925 245c2cdab58181326305ede7c5700eff 247 PRINTS PR01900 YidC translocation/secretion protein signature 40 56 8.1E-5 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CB4_RS01925 245c2cdab58181326305ede7c5700eff 247 PRINTS PR00701 60kDa inner membrane protein signature 162 184 7.4E-15 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CB4_RS01925 245c2cdab58181326305ede7c5700eff 247 PRINTS PR00701 60kDa inner membrane protein signature 117 140 7.4E-15 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CB4_RS01925 245c2cdab58181326305ede7c5700eff 247 Pfam PF02096 60Kd inner membrane protein 56 237 1.6E-61 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CB4_RS12440 783f592d2c607c9b13c8dce33f465167 169 Pfam PF00994 Probable molybdopterin binding domain 18 161 4.6E-33 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS12440 783f592d2c607c9b13c8dce33f465167 169 Gene3D G3DSA:3.40.980.10 1 168 2.4E-31 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS12440 783f592d2c607c9b13c8dce33f465167 169 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 16 157 3.6E-35 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS12440 783f592d2c607c9b13c8dce33f465167 169 PIRSF PIRSF006443 1 169 7.3E-65 T 29-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 CB4_RS12440 783f592d2c607c9b13c8dce33f465167 169 SUPERFAMILY SSF53218 9 165 3.14E-41 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS12440 783f592d2c607c9b13c8dce33f465167 169 SMART SM00852 17 162 1.6E-26 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS15130 f73c9b8cda8de31586749ccceed81ba1 124 Pfam PF07736 Chorismate mutase type I 3 119 5.5E-45 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CB4_RS15130 f73c9b8cda8de31586749ccceed81ba1 124 PIRSF PIRSF005965 1 124 2.7E-46 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CB4_RS15130 f73c9b8cda8de31586749ccceed81ba1 124 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 119 5.0E-45 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CB4_RS15130 f73c9b8cda8de31586749ccceed81ba1 124 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 124 4.0E-32 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CB4_RS15130 f73c9b8cda8de31586749ccceed81ba1 124 SUPERFAMILY SSF55298 1 120 4.71E-44 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CB4_RS15130 f73c9b8cda8de31586749ccceed81ba1 124 Gene3D G3DSA:3.30.1330.40 3 120 3.2E-47 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CB4_RS03650 defbc42d39f75aaba7044297d5e0d564 218 Gene3D G3DSA:1.10.150.240 29 72 1.1E-13 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CB4_RS03650 defbc42d39f75aaba7044297d5e0d564 218 SUPERFAMILY SSF56784 3 213 5.78E-56 T 29-03-2018 IPR023214 HAD-like domain CB4_RS03650 defbc42d39f75aaba7044297d5e0d564 218 Gene3D G3DSA:3.40.50.1000 73 218 1.2E-31 T 29-03-2018 IPR023214 HAD-like domain CB4_RS03650 defbc42d39f75aaba7044297d5e0d564 218 Gene3D G3DSA:3.40.50.1000 1 28 0.096 T 29-03-2018 IPR023214 HAD-like domain CB4_RS03650 defbc42d39f75aaba7044297d5e0d564 218 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 98 176 1.8E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS03650 defbc42d39f75aaba7044297d5e0d564 218 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 71 180 2.7E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS03650 defbc42d39f75aaba7044297d5e0d564 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 182 3.8E-47 T 29-03-2018 IPR023214 HAD-like domain CB4_RS05820 74195a1af2e9696be0a1db18ed39c76a 172 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 9 157 1.7E-18 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CB4_RS05820 74195a1af2e9696be0a1db18ed39c76a 172 Pfam PF04093 rod shape-determining protein MreD 7 161 1.7E-18 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 SUPERFAMILY SSF103190 92 178 4.71E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 SUPERFAMILY SSF58104 386 655 2.22E-76 T 29-03-2018 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 SUPERFAMILY SSF58104 319 353 2.22E-76 T 29-03-2018 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 Gene3D G3DSA:3.30.450.20 156 278 2.6E-25 T 29-03-2018 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 SMART SM00283 380 655 2.1E-80 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 Pfam PF02743 Cache domain 41 260 9.0E-30 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 441 609 6.9E-44 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 Gene3D G3DSA:1.10.287.950 326 406 8.2E-6 T 29-03-2018 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 SMART SM00304 299 351 3.6E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 Pfam PF00672 HAMP domain 300 348 3.1E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 Gene3D G3DSA:1.10.287.950 407 656 1.6E-56 T 29-03-2018 CB4_RS12215 219f750cb2cece528cd6eaa05cdac11b 656 Gene3D G3DSA:3.30.450.20 53 155 1.2E-16 T 29-03-2018 CB4_RS08990 4cbadba60cb0932289a5004028ad692a 250 SUPERFAMILY SSF53187 3 183 1.76E-35 T 29-03-2018 CB4_RS08990 4cbadba60cb0932289a5004028ad692a 250 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 5 179 1.4E-26 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CB4_RS08990 4cbadba60cb0932289a5004028ad692a 250 SMART SM00646 74 180 2.6E-6 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CB4_RS08990 4cbadba60cb0932289a5004028ad692a 250 Gene3D G3DSA:3.40.630.40 1 182 7.8E-35 T 29-03-2018 CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 153 252 6.9E-22 T 29-03-2018 IPR000014 PAS domain CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 120 1.3E-9 T 29-03-2018 IPR000014 PAS domain CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 SMART SM00331 273 489 1.3E-32 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 Gene3D G3DSA:3.30.450.20 131 249 5.1E-31 T 29-03-2018 CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 SUPERFAMILY SSF55785 5 111 1.05E-15 T 29-03-2018 IPR000014 PAS domain CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 SUPERFAMILY SSF55785 139 245 6.11E-29 T 29-03-2018 IPR000014 PAS domain CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 Gene3D G3DSA:3.60.40.10 250 490 6.7E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 300 488 1.8E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 SUPERFAMILY SSF81606 290 489 9.15E-7 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 Pfam PF13426 PAS domain 149 243 7.2E-24 T 29-03-2018 IPR000014 PAS domain CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 SMART SM00086 203 245 2.9E-12 T 29-03-2018 IPR001610 PAC motif CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 SMART SM00091 8 74 1.0E-9 T 29-03-2018 IPR000014 PAS domain CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 SMART SM00091 128 197 0.0072 T 29-03-2018 IPR000014 PAS domain CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 Gene3D G3DSA:3.30.450.20 2 130 6.0E-21 T 29-03-2018 CB4_RS16795 2563fa88d0f7650ed4278a090312fd7e 490 Pfam PF08448 PAS fold 15 115 2.0E-15 T 29-03-2018 IPR013656 PAS fold-4 CB4_RS02950 a022a95eaa74e56a2febd2a0986ca60d 251 PRINTS PR00123 ATP synthase A subunit signature 67 83 1.2E-6 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02950 a022a95eaa74e56a2febd2a0986ca60d 251 PRINTS PR00123 ATP synthase A subunit signature 230 245 1.2E-6 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02950 a022a95eaa74e56a2febd2a0986ca60d 251 Gene3D G3DSA:1.20.120.220 58 251 2.0E-40 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02950 a022a95eaa74e56a2febd2a0986ca60d 251 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 3 246 2.8E-39 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02950 a022a95eaa74e56a2febd2a0986ca60d 251 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 250 13.132 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02950 a022a95eaa74e56a2febd2a0986ca60d 251 Pfam PF00119 ATP synthase A chain 8 244 7.9E-53 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02950 a022a95eaa74e56a2febd2a0986ca60d 251 SUPERFAMILY SSF81336 59 101 3.66E-29 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02950 a022a95eaa74e56a2febd2a0986ca60d 251 SUPERFAMILY SSF81336 126 244 3.66E-29 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 44.691 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 PRINTS PR00395 Ribosomal protein S2 signature 158 175 4.9E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 PRINTS PR00395 Ribosomal protein S2 signature 196 210 4.9E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 PRINTS PR00395 Ribosomal protein S2 signature 37 46 4.9E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 PRINTS PR00395 Ribosomal protein S2 signature 87 104 4.9E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 PRINTS PR00395 Ribosomal protein S2 signature 6 24 4.9E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 PRINTS PR00395 Ribosomal protein S2 signature 175 186 4.9E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 Pfam PF00318 Ribosomal protein S2 9 224 3.3E-103 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 2.1E-113 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 SUPERFAMILY SSF52313 6 227 5.62E-101 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CB4_RS09260 2cb98c7a004cc55585c5a3be4206e1b6 238 Gene3D G3DSA:3.40.50.10490 5 237 5.9E-105 T 29-03-2018 CB4_RS10755 c2e81146d32a71529fcd7f7378a1b574 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.6E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS10755 c2e81146d32a71529fcd7f7378a1b574 304 SUPERFAMILY SSF53850 91 297 1.3E-48 T 29-03-2018 CB4_RS10755 c2e81146d32a71529fcd7f7378a1b574 304 Gene3D G3DSA:1.10.10.10 1 83 2.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS10755 c2e81146d32a71529fcd7f7378a1b574 304 Gene3D G3DSA:3.40.190.10 180 268 2.2E-30 T 29-03-2018 CB4_RS10755 c2e81146d32a71529fcd7f7378a1b574 304 Gene3D G3DSA:3.40.190.10 89 179 4.9E-26 T 29-03-2018 CB4_RS10755 c2e81146d32a71529fcd7f7378a1b574 304 Pfam PF03466 LysR substrate binding domain 90 294 7.6E-56 T 29-03-2018 IPR005119 LysR, substrate-binding CB4_RS10755 c2e81146d32a71529fcd7f7378a1b574 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS10755 c2e81146d32a71529fcd7f7378a1b574 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS10755 c2e81146d32a71529fcd7f7378a1b574 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS10755 c2e81146d32a71529fcd7f7378a1b574 304 SUPERFAMILY SSF46785 2 85 2.43E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12530 c4d9e7851dcd25d905bf400ee703fa8a 354 SUPERFAMILY SSF53901 4 349 1.14E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS12530 c4d9e7851dcd25d905bf400ee703fa8a 354 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 4 201 5.1E-24 T 29-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal CB4_RS12530 c4d9e7851dcd25d905bf400ee703fa8a 354 Gene3D G3DSA:3.40.47.10 2 203 3.9E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS12530 c4d9e7851dcd25d905bf400ee703fa8a 354 Gene3D G3DSA:3.40.47.10 209 352 3.3E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS12530 c4d9e7851dcd25d905bf400ee703fa8a 354 PIRSF PIRSF000451 1 353 2.7E-119 T 29-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 CB4_RS12530 c4d9e7851dcd25d905bf400ee703fa8a 354 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 212 351 5.6E-17 T 29-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal CB4_RS07025 593eb00252d1b90b827769b5beabc0d5 439 SUPERFAMILY SSF55874 280 428 1.57E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS07025 593eb00252d1b90b827769b5beabc0d5 439 Gene3D G3DSA:3.30.565.10 202 429 1.2E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS07025 593eb00252d1b90b827769b5beabc0d5 439 SMART SM00387 318 430 1.8E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS07025 593eb00252d1b90b827769b5beabc0d5 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 383 1.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS07025 593eb00252d1b90b827769b5beabc0d5 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 1.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS07025 593eb00252d1b90b827769b5beabc0d5 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 407 1.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS07025 593eb00252d1b90b827769b5beabc0d5 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 427 1.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS07025 593eb00252d1b90b827769b5beabc0d5 439 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 323 428 1.7E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS06350 94b47a373675d5f61f36d43c6b71f4e0 329 Gene3D G3DSA:3.40.50.300 2 230 4.6E-6 T 29-03-2018 CB4_RS06350 94b47a373675d5f61f36d43c6b71f4e0 329 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 10 95 1.9E-15 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CB4_RS06350 94b47a373675d5f61f36d43c6b71f4e0 329 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 130 312 8.4E-39 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CB4_RS06395 e2ffcf44974fef21d4e9eb64486bf2b7 202 Pfam PF07238 PilZ domain 84 187 2.6E-9 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CB4_RS06395 e2ffcf44974fef21d4e9eb64486bf2b7 202 Gene3D G3DSA:2.40.10.220 84 193 1.3E-12 T 29-03-2018 CB4_RS06395 e2ffcf44974fef21d4e9eb64486bf2b7 202 SUPERFAMILY SSF141371 81 187 7.45E-8 T 29-03-2018 CB4_RS11190 703b82447ca5fda9643793cb99ec96f1 493 Gene3D G3DSA:3.40.50.300 213 256 0.3 T 29-03-2018 CB4_RS11190 703b82447ca5fda9643793cb99ec96f1 493 Pfam PF02706 Chain length determinant protein 25 112 3.1E-16 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CB4_RS11190 703b82447ca5fda9643793cb99ec96f1 493 Gene3D G3DSA:3.30.1890.10 57 179 2.9E-8 T 29-03-2018 CB4_RS11190 703b82447ca5fda9643793cb99ec96f1 493 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 295 491 4.9E-44 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CB4_RS11190 703b82447ca5fda9643793cb99ec96f1 493 SUPERFAMILY SSF52540 313 483 3.92E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11190 703b82447ca5fda9643793cb99ec96f1 493 Pfam PF13614 AAA domain 313 456 1.4E-13 T 29-03-2018 IPR025669 AAA domain CB4_RS11190 703b82447ca5fda9643793cb99ec96f1 493 Gene3D G3DSA:3.40.50.300 298 486 1.3E-28 T 29-03-2018 CB4_RS08685 35dcdba5fe9b47f33f0e31ac679cf65a 253 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 230 1.3E-69 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CB4_RS08685 35dcdba5fe9b47f33f0e31ac679cf65a 253 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 235 8.8E-97 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CB4_RS08685 35dcdba5fe9b47f33f0e31ac679cf65a 253 SUPERFAMILY SSF75217 1 251 3.98E-99 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CB4_RS08685 35dcdba5fe9b47f33f0e31ac679cf65a 253 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 253 110.016 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CB4_RS08685 35dcdba5fe9b47f33f0e31ac679cf65a 253 Gene3D G3DSA:1.10.1270.20 179 253 4.3E-33 T 29-03-2018 CB4_RS08685 35dcdba5fe9b47f33f0e31ac679cf65a 253 PIRSF PIRSF000386 1 253 2.1E-102 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CB4_RS08685 35dcdba5fe9b47f33f0e31ac679cf65a 253 Gene3D G3DSA:3.40.1280.10 1 178 2.7E-75 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CB4_RS10840 8ff5990578d3b7bb2a5f5a964a75c208 111 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 4 103 6.3E-16 T 29-03-2018 IPR009799 EthD domain CB4_RS10840 8ff5990578d3b7bb2a5f5a964a75c208 111 SUPERFAMILY SSF54909 16 103 1.72E-11 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CB4_RS10840 8ff5990578d3b7bb2a5f5a964a75c208 111 Gene3D G3DSA:3.30.70.100 4 102 2.7E-13 T 29-03-2018 CB4_RS03910 dfc386f37057b5f9eebec994019e154b 154 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 4.0E-51 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CB4_RS03910 dfc386f37057b5f9eebec994019e154b 154 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site CB4_RS03910 dfc386f37057b5f9eebec994019e154b 154 Hamap MF_00023 SsrA-binding protein [smpB]. 1 154 78.017 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CB4_RS03910 dfc386f37057b5f9eebec994019e154b 154 SUPERFAMILY SSF74982 3 132 5.62E-55 T 29-03-2018 IPR023620 Small protein B CB4_RS03910 dfc386f37057b5f9eebec994019e154b 154 Pfam PF01668 SmpB protein 9 150 2.5E-64 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CB4_RS03910 dfc386f37057b5f9eebec994019e154b 154 Gene3D G3DSA:2.40.280.10 9 127 5.5E-53 T 29-03-2018 IPR023620 Small protein B CB4_RS03910 dfc386f37057b5f9eebec994019e154b 154 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 149 1.1E-60 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 SUPERFAMILY SSF53067 147 330 2.63E-49 T 29-03-2018 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 Gene3D G3DSA:3.30.420.40 251 314 9.3E-9 T 29-03-2018 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 Gene3D G3DSA:3.30.420.40 158 191 8.6E-4 T 29-03-2018 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 Gene3D G3DSA:3.90.640.10 192 250 6.9E-31 T 29-03-2018 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 5 333 3.0E-157 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 2.2E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 129 148 2.2E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 297 323 2.2E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 184 204 2.2E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 2.2E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 SUPERFAMILY SSF53067 5 143 1.77E-39 T 29-03-2018 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 Gene3D G3DSA:3.30.420.40 4 157 1.1E-39 T 29-03-2018 CB4_RS05810 a629d8413f7d927d8876fbd1bbafd822 346 Pfam PF06723 MreB/Mbl protein 7 331 1.1E-149 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CB4_RS16790 200a227089481e28eb42046ed926cfb1 99 SUPERFAMILY SSF52091 5 98 1.9E-14 T 29-03-2018 IPR002645 STAS domain CB4_RS16790 200a227089481e28eb42046ed926cfb1 99 Pfam PF01740 STAS domain 11 96 1.0E-10 T 29-03-2018 IPR002645 STAS domain CB4_RS16790 200a227089481e28eb42046ed926cfb1 99 Gene3D G3DSA:3.30.750.24 2 99 6.8E-13 T 29-03-2018 IPR002645 STAS domain CB4_RS19645 b5701cbb0cc2e8631f2c4b7f1956327a 199 Gene3D G3DSA:1.10.3540.10 5 193 9.3E-41 T 29-03-2018 CB4_RS19645 b5701cbb0cc2e8631f2c4b7f1956327a 199 Pfam PF08849 Putative inner membrane protein (DUF1819) 7 186 2.1E-44 T 29-03-2018 IPR014948 Protein of unknown function DUF1819, putative inner membrane CB4_RS10500 a875e20fd3059c42bf1cc5a22e145fa8 489 SUPERFAMILY SSF53041 1 148 7.59E-40 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS10500 a875e20fd3059c42bf1cc5a22e145fa8 489 Pfam PF13408 Recombinase zinc beta ribbon domain 287 344 1.5E-11 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain CB4_RS10500 a875e20fd3059c42bf1cc5a22e145fa8 489 Pfam PF07508 Recombinase 171 272 1.3E-22 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CB4_RS10500 a875e20fd3059c42bf1cc5a22e145fa8 489 Gene3D G3DSA:3.40.50.1390 1 120 6.8E-44 T 29-03-2018 CB4_RS10500 a875e20fd3059c42bf1cc5a22e145fa8 489 Pfam PF00239 Resolvase, N terminal domain 3 150 1.4E-42 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS10500 a875e20fd3059c42bf1cc5a22e145fa8 489 SMART SM00857 3 151 1.7E-60 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS10500 a875e20fd3059c42bf1cc5a22e145fa8 489 Gene3D G3DSA:1.20.5.40 121 149 1.0E-9 T 29-03-2018 CB4_RS10500 a875e20fd3059c42bf1cc5a22e145fa8 489 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CB4_RS00930 9c8fa0d2d5fed812df94109f81907a51 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 9.1E-52 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00930 9c8fa0d2d5fed812df94109f81907a51 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 31.177 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00930 9c8fa0d2d5fed812df94109f81907a51 110 Gene3D G3DSA:3.90.470.10 1 110 6.2E-45 T 29-03-2018 CB4_RS00930 9c8fa0d2d5fed812df94109f81907a51 110 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 1.1E-37 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CB4_RS00930 9c8fa0d2d5fed812df94109f81907a51 110 SUPERFAMILY SSF54843 1 110 2.62E-45 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CB4_RS00930 9c8fa0d2d5fed812df94109f81907a51 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS02590 c1d7072e923e599901c477932f136fcb 274 Pfam PF01522 Polysaccharide deacetylase 59 171 1.4E-25 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS02590 c1d7072e923e599901c477932f136fcb 274 SUPERFAMILY SSF88713 56 261 3.46E-45 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS02590 c1d7072e923e599901c477932f136fcb 274 Gene3D G3DSA:3.20.20.370 42 262 1.4E-43 T 29-03-2018 CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 SMART SM00052 318 564 1.8E-115 T 29-03-2018 IPR001633 EAL domain CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 SUPERFAMILY SSF141868 324 571 3.53E-90 T 29-03-2018 IPR001633 EAL domain CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 Pfam PF00563 EAL domain 325 559 6.1E-78 T 29-03-2018 IPR001633 EAL domain CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 Pfam PF00990 Diguanylate cyclase, GGDEF domain 149 304 5.8E-40 T 29-03-2018 IPR000160 GGDEF domain CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 SUPERFAMILY SSF55073 153 311 3.69E-39 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 Gene3D G3DSA:3.30.70.270 141 313 1.4E-46 T 29-03-2018 CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 Gene3D G3DSA:3.30.450.20 13 135 9.2E-7 T 29-03-2018 CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 Gene3D G3DSA:3.20.20.450 314 574 3.4E-100 T 29-03-2018 IPR001633 EAL domain CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 SUPERFAMILY SSF55785 21 135 6.51E-6 T 29-03-2018 IPR000014 PAS domain CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 SMART SM00267 137 309 7.7E-39 T 29-03-2018 IPR000160 GGDEF domain CB4_RS11245 323d24fd17bc4ebf548a972db3f7956e 574 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 146 307 2.9E-31 T 29-03-2018 IPR000160 GGDEF domain CB4_RS13565 3e1ac52bfceb9eb7d1d96990ab61663b 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 50 9.6E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS13565 3e1ac52bfceb9eb7d1d96990ab61663b 190 SUPERFAMILY SSF46689 3 68 2.05E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS13565 3e1ac52bfceb9eb7d1d96990ab61663b 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 7.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS13565 3e1ac52bfceb9eb7d1d96990ab61663b 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 7.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS13565 3e1ac52bfceb9eb7d1d96990ab61663b 190 Gene3D G3DSA:1.10.357.10 48 190 1.7E-12 T 29-03-2018 CB4_RS13565 3e1ac52bfceb9eb7d1d96990ab61663b 190 Gene3D G3DSA:1.10.10.60 1 47 3.4E-13 T 29-03-2018 CB4_RS13565 3e1ac52bfceb9eb7d1d96990ab61663b 190 SUPERFAMILY SSF48498 74 173 1.51E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS17025 7c79343be436983b9af7573822ae4f72 299 SMART SM00014 162 265 0.0051 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS17025 7c79343be436983b9af7573822ae4f72 299 SUPERFAMILY SSF48317 84 278 2.22E-12 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS17025 7c79343be436983b9af7573822ae4f72 299 Pfam PF01569 PAP2 superfamily 198 264 1.9E-11 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS17025 7c79343be436983b9af7573822ae4f72 299 Gene3D G3DSA:1.20.144.10 4 285 4.2E-10 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS09765 4a23d9d9db9965b4b9273acee59e08f1 216 Pfam PF01323 DSBA-like thioredoxin domain 5 193 7.7E-32 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CB4_RS09765 4a23d9d9db9965b4b9273acee59e08f1 216 Gene3D G3DSA:3.40.30.10 3 205 2.9E-44 T 29-03-2018 CB4_RS09765 4a23d9d9db9965b4b9273acee59e08f1 216 SUPERFAMILY SSF52833 1 200 1.62E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS17125 dd9364ee96e96dd4360e73799e51efdb 103 Pfam PF02517 CAAX protease self-immunity 2 87 9.2E-16 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CB4_RS04275 49a325b48b376f69a8827ba884c1d6b0 367 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 9 357 2.3E-94 T 29-03-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 CB4_RS04275 49a325b48b376f69a8827ba884c1d6b0 367 Gene3D G3DSA:3.90.1150.10 251 366 2.4E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS04275 49a325b48b376f69a8827ba884c1d6b0 367 Pfam PF00155 Aminotransferase class I and II 27 356 1.6E-35 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS04275 49a325b48b376f69a8827ba884c1d6b0 367 SUPERFAMILY SSF53383 9 361 9.44E-72 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS04275 49a325b48b376f69a8827ba884c1d6b0 367 Gene3D G3DSA:3.40.640.10 39 250 1.2E-35 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS04275 49a325b48b376f69a8827ba884c1d6b0 367 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 216 229 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CB4_RS13155 42807bf969ee5507d9e2f0f41ba31612 582 SUPERFAMILY SSF51556 72 318 1.74E-40 T 29-03-2018 IPR032466 Metal-dependent hydrolase CB4_RS13155 42807bf969ee5507d9e2f0f41ba31612 582 Pfam PF13382 Adenine deaminase C-terminal domain 407 574 1.3E-66 T 29-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CB4_RS13155 42807bf969ee5507d9e2f0f41ba31612 582 Gene3D G3DSA:2.30.40.10 258 360 1.1E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS13155 42807bf969ee5507d9e2f0f41ba31612 582 Gene3D G3DSA:3.20.20.140 77 255 1.5E-14 T 29-03-2018 CB4_RS13155 42807bf969ee5507d9e2f0f41ba31612 582 SUPERFAMILY SSF51338 20 72 7.41E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS13155 42807bf969ee5507d9e2f0f41ba31612 582 SUPERFAMILY SSF51338 320 358 7.41E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS13155 42807bf969ee5507d9e2f0f41ba31612 582 Pfam PF01979 Amidohydrolase family 68 348 2.5E-32 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CB4_RS13155 42807bf969ee5507d9e2f0f41ba31612 582 Hamap MF_01518 Adenine deaminase [ade]. 22 578 40.627 T 29-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CB4_RS13155 42807bf969ee5507d9e2f0f41ba31612 582 Gene3D G3DSA:2.30.40.10 18 76 3.0E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS13155 42807bf969ee5507d9e2f0f41ba31612 582 TIGRFAM TIGR01178 ade: adenine deaminase 22 578 5.5E-206 T 29-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CB4_RS12950 a1926b92c578add70cc4d2250e057cbe 309 Pfam PF07833 Copper amine oxidase N-terminal domain 67 146 2.3E-13 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS12950 a1926b92c578add70cc4d2250e057cbe 309 SUPERFAMILY SSF55383 69 145 2.49E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS12950 a1926b92c578add70cc4d2250e057cbe 309 Pfam PF14285 Domain of unknown function (DUF4367) 205 291 3.6E-6 T 29-03-2018 IPR025377 Domain of unknown function DUF4367 CB4_RS12950 a1926b92c578add70cc4d2250e057cbe 309 Gene3D G3DSA:3.30.457.10 16 77 5.8E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS12950 a1926b92c578add70cc4d2250e057cbe 309 Gene3D G3DSA:3.30.457.10 78 147 5.4E-14 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS16815 aa4a4ba96a83d994a4b76423afd17307 229 SMART SM00882 4 215 3.0E-97 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CB4_RS16815 aa4a4ba96a83d994a4b76423afd17307 229 SUPERFAMILY SSF100950 3 225 1.54E-89 T 29-03-2018 CB4_RS16815 aa4a4ba96a83d994a4b76423afd17307 229 Pfam PF01144 Coenzyme A transferase 5 214 4.4E-78 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CB4_RS16815 aa4a4ba96a83d994a4b76423afd17307 229 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 16 31 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CB4_RS16815 aa4a4ba96a83d994a4b76423afd17307 229 Gene3D G3DSA:3.40.1080.10 1 229 5.0E-99 T 29-03-2018 CB4_RS16815 aa4a4ba96a83d994a4b76423afd17307 229 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 4 217 1.2E-82 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CB4_RS17950 c629f0895c12781f98f7f1bf0e9f0502 319 Pfam PF00753 Metallo-beta-lactamase superfamily 23 232 1.3E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS17950 c629f0895c12781f98f7f1bf0e9f0502 319 SUPERFAMILY SSF56281 5 316 4.46E-60 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS17950 c629f0895c12781f98f7f1bf0e9f0502 319 Gene3D G3DSA:3.60.15.10 2 260 1.5E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS17950 c629f0895c12781f98f7f1bf0e9f0502 319 SMART SM00849 19 232 1.4E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 2.2E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 2.2E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 2.2E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 Gene3D G3DSA:3.40.50.720 8 258 3.5E-63 T 29-03-2018 CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 SUPERFAMILY SSF51735 15 244 2.55E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 19 205 3.0E-4 T 29-03-2018 CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 1.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 1.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 1.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS02105 5177a0dc18ecf16f0b1999af274a2ea4 262 Pfam PF00106 short chain dehydrogenase 19 207 1.5E-54 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS00960 754eaa932b84460daee61a011a66956a 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.441 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00960 754eaa932b84460daee61a011a66956a 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00960 754eaa932b84460daee61a011a66956a 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.9E-47 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00960 754eaa932b84460daee61a011a66956a 102 Gene3D G3DSA:3.30.70.600 3 102 2.1E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CB4_RS00960 754eaa932b84460daee61a011a66956a 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.1E-19 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00960 754eaa932b84460daee61a011a66956a 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.1E-19 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00960 754eaa932b84460daee61a011a66956a 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.1E-19 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00960 754eaa932b84460daee61a011a66956a 102 SUPERFAMILY SSF54999 5 102 1.16E-38 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CB4_RS00960 754eaa932b84460daee61a011a66956a 102 SMART SM01403 7 101 6.8E-61 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CB4_RS00960 754eaa932b84460daee61a011a66956a 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.3E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CB4_RS14635 85cff0409b67c766a4fbd6933a5b11c9 84 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 41 77 5.7E-14 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CB4_RS14635 85cff0409b67c766a4fbd6933a5b11c9 84 Gene3D G3DSA:3.30.65.10 19 83 6.9E-16 T 29-03-2018 CB4_RS14635 85cff0409b67c766a4fbd6933a5b11c9 84 SUPERFAMILY SSF57783 27 78 1.04E-11 T 29-03-2018 CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 SMART SM00646 432 539 9.5E-43 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 SUPERFAMILY SSF53187 370 544 5.23E-56 T 29-03-2018 CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 Gene3D G3DSA:3.40.630.40 356 546 5.1E-64 T 29-03-2018 CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 Gene3D G3DSA:3.30.457.10 21 58 2.8E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 Gene3D G3DSA:3.30.457.10 123 214 1.2E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 Gene3D G3DSA:3.30.457.10 59 122 1.8E-21 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 Pfam PF11741 AMIN domain 254 330 2.1E-10 T 29-03-2018 IPR021731 AMIN domain CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 SUPERFAMILY SSF55383 50 134 1.18E-22 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 Pfam PF07833 Copper amine oxidase N-terminal domain 48 140 3.7E-25 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 Pfam PF07833 Copper amine oxidase N-terminal domain 30 77 1.2E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS10455 48aa684a9b529e9dcb36b23101a25cd6 546 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 372 539 1.4E-51 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CB4_RS13930 34d4902ea6a1395c52e59c4db2d897c6 59 SUPERFAMILY SSF56349 2 59 4.59E-10 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS13930 34d4902ea6a1395c52e59c4db2d897c6 59 Gene3D G3DSA:1.10.150.130 1 51 7.1E-11 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CB4_RS03680 b842a43f3ef73a622531aa166b9774f8 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CB4_RS03680 b842a43f3ef73a622531aa166b9774f8 194 Gene3D G3DSA:3.30.230.40 2 88 3.7E-33 T 29-03-2018 CB4_RS03680 b842a43f3ef73a622531aa166b9774f8 194 Gene3D G3DSA:3.30.230.40 90 194 2.1E-33 T 29-03-2018 CB4_RS03680 b842a43f3ef73a622531aa166b9774f8 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 6.1E-64 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CB4_RS03680 b842a43f3ef73a622531aa166b9774f8 194 SUPERFAMILY SSF54211 1 86 1.52E-32 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS03680 b842a43f3ef73a622531aa166b9774f8 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CB4_RS03680 b842a43f3ef73a622531aa166b9774f8 194 SUPERFAMILY SSF54211 87 178 1.52E-33 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS03680 b842a43f3ef73a622531aa166b9774f8 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 41.655 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CB4_RS12360 90976dce2abb5fb48624dce2b7480d38 434 Gene3D G3DSA:3.30.360.10 148 298 3.0E-52 T 29-03-2018 CB4_RS12360 90976dce2abb5fb48624dce2b7480d38 434 PIRSF PIRSF000098 1 408 7.0E-123 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CB4_RS12360 90976dce2abb5fb48624dce2b7480d38 434 SUPERFAMILY SSF55347 136 301 6.28E-46 T 29-03-2018 CB4_RS12360 90976dce2abb5fb48624dce2b7480d38 434 Gene3D G3DSA:3.40.50.720 1 147 8.8E-26 T 29-03-2018 CB4_RS12360 90976dce2abb5fb48624dce2b7480d38 434 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 128 1.6E-17 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CB4_RS12360 90976dce2abb5fb48624dce2b7480d38 434 SUPERFAMILY SSF51735 1 157 3.0E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS12360 90976dce2abb5fb48624dce2b7480d38 434 Pfam PF00742 Homoserine dehydrogenase 136 314 8.3E-58 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CB4_RS12360 90976dce2abb5fb48624dce2b7480d38 434 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 182 204 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CB4_RS17470 c7afcb7fc36ad32e2b731733602702e1 204 SUPERFAMILY SSF52980 35 202 9.38E-64 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CB4_RS17470 c7afcb7fc36ad32e2b731733602702e1 204 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 204 86.647 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CB4_RS17470 c7afcb7fc36ad32e2b731733602702e1 204 Pfam PF03838 Recombination protein U 33 199 3.2E-66 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CB4_RS17470 c7afcb7fc36ad32e2b731733602702e1 204 TIGRFAM TIGR00648 recU: recombination protein U 32 200 7.9E-69 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CB4_RS17470 c7afcb7fc36ad32e2b731733602702e1 204 PIRSF PIRSF037785 24 204 3.4E-76 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CB4_RS17470 c7afcb7fc36ad32e2b731733602702e1 204 Gene3D G3DSA:3.40.1350.10 34 201 3.7E-62 T 29-03-2018 CB4_RS04890 83cda40962400d3ae8ca735511d8171e 327 Pfam PF03060 Nitronate monooxygenase 7 312 3.9E-56 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CB4_RS04890 83cda40962400d3ae8ca735511d8171e 327 Gene3D G3DSA:3.20.20.70 2 324 1.2E-56 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS04890 83cda40962400d3ae8ca735511d8171e 327 SUPERFAMILY SSF51412 7 307 7.33E-64 T 29-03-2018 CB4_RS11885 1cd56fef50de360568e444fa3ce9390e 237 Gene3D G3DSA:1.10.10.10 102 147 0.0027 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS11885 1cd56fef50de360568e444fa3ce9390e 237 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 226 4.9E-17 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11885 1cd56fef50de360568e444fa3ce9390e 237 SUPERFAMILY SSF88946 4 95 2.51E-14 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11885 1cd56fef50de360568e444fa3ce9390e 237 Gene3D G3DSA:1.10.1740.10 7 94 1.5E-14 T 29-03-2018 CB4_RS11885 1cd56fef50de360568e444fa3ce9390e 237 SUPERFAMILY SSF88659 104 167 7.85E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11885 1cd56fef50de360568e444fa3ce9390e 237 Pfam PF04542 Sigma-70 region 2 46 95 2.1E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11885 1cd56fef50de360568e444fa3ce9390e 237 SUPERFAMILY SSF88659 189 227 3.71E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11885 1cd56fef50de360568e444fa3ce9390e 237 Gene3D G3DSA:1.10.10.10 158 236 1.5E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS01290 4e94d485d270c0f4ac121b3793aa693f 395 Gene3D G3DSA:3.40.190.10 72 203 9.6E-34 T 29-03-2018 CB4_RS01290 4e94d485d270c0f4ac121b3793aa693f 395 PIRSF PIRSF002756 27 389 1.1E-121 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CB4_RS01290 4e94d485d270c0f4ac121b3793aa693f 395 SUPERFAMILY SSF53850 74 389 5.14E-95 T 29-03-2018 CB4_RS01290 4e94d485d270c0f4ac121b3793aa693f 395 Pfam PF12849 PBP superfamily domain 67 358 1.4E-67 T 29-03-2018 IPR024370 PBP domain CB4_RS01290 4e94d485d270c0f4ac121b3793aa693f 395 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 74 385 4.6E-108 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CB4_RS01290 4e94d485d270c0f4ac121b3793aa693f 395 Gene3D G3DSA:3.40.190.10 204 387 1.3E-23 T 29-03-2018 CB4_RS03595 ccdb202b74b84a48199c5719ee2ff2ad 232 SUPERFAMILY SSF52540 1 227 5.87E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03595 ccdb202b74b84a48199c5719ee2ff2ad 232 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 218 8.5E-83 T 29-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CB4_RS03595 ccdb202b74b84a48199c5719ee2ff2ad 232 Pfam PF00005 ABC transporter 18 169 7.7E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS03595 ccdb202b74b84a48199c5719ee2ff2ad 232 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS03595 ccdb202b74b84a48199c5719ee2ff2ad 232 Gene3D G3DSA:3.40.50.300 1 230 3.4E-62 T 29-03-2018 CB4_RS03595 ccdb202b74b84a48199c5719ee2ff2ad 232 SMART SM00382 27 226 3.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 Gene3D G3DSA:3.30.450.20 123 246 1.6E-7 T 29-03-2018 CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 291 304 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 SUPERFAMILY SSF46689 522 575 4.35E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 Gene3D G3DSA:3.30.450.20 21 122 8.9E-5 T 29-03-2018 CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 Gene3D G3DSA:1.10.10.60 506 576 6.6E-10 T 29-03-2018 CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 Pfam PF00158 Sigma-54 interaction domain 270 433 5.7E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 353 368 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 Gene3D G3DSA:3.40.50.300 262 439 3.3E-25 T 29-03-2018 CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 SMART SM00382 287 430 3.6E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 Gene3D G3DSA:1.10.8.60 440 505 2.0E-24 T 29-03-2018 CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 SUPERFAMILY SSF55785 121 223 1.83E-8 T 29-03-2018 IPR000014 PAS domain CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 SUPERFAMILY SSF52540 266 509 3.58E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS16130 42ab55d9a7d6b815b369f16ed8ca2d7a 587 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 479 488 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CB4_RS01105 10f620a0ada52f85136006616129f24b 693 SUPERFAMILY SSF50447 264 403 1.46E-36 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Pfam PF03144 Elongation factor Tu domain 2 323 390 2.8E-15 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Gene3D G3DSA:3.30.70.870 398 490 7.3E-35 T 29-03-2018 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.2E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 PRINTS PR00315 GTP-binding elongation factor signature 130 139 2.2E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.2E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.2E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 PRINTS PR00315 GTP-binding elongation factor signature 12 25 2.2E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 SUPERFAMILY SSF54211 478 598 4.3E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Gene3D G3DSA:3.40.50.300 1 281 1.3E-59 T 29-03-2018 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 SMART SM00838 599 686 2.8E-59 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CB4_RS01105 10f620a0ada52f85136006616129f24b 693 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 181 3.6E-43 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 691 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Pfam PF00009 Elongation factor Tu GTP binding domain 9 281 6.8E-70 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Gene3D G3DSA:3.30.230.10 491 612 2.3E-41 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS01105 10f620a0ada52f85136006616129f24b 693 SUPERFAMILY SSF54980 600 689 9.59E-32 T 29-03-2018 IPR035647 EF-G domain III/V-like CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Pfam PF03764 Elongation factor G, domain IV 478 596 8.1E-46 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Pfam PF00679 Elongation factor G C-terminus 600 685 1.2E-32 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CB4_RS01105 10f620a0ada52f85136006616129f24b 693 SMART SM00889 479 597 1.0E-67 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 SUPERFAMILY SSF52540 6 281 4.28E-108 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Hamap MF_00054_B Elongation factor G [fusA]. 6 690 110.972 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Pfam PF14492 Elongation Factor G, domain II 403 476 1.3E-35 T 29-03-2018 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Gene3D G3DSA:2.40.30.10 282 397 1.7E-30 T 29-03-2018 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CB4_RS01105 10f620a0ada52f85136006616129f24b 693 Gene3D G3DSA:3.30.70.240 613 690 1.5E-33 T 29-03-2018 CB4_RS01105 10f620a0ada52f85136006616129f24b 693 SUPERFAMILY SSF54980 401 479 3.96E-25 T 29-03-2018 IPR035647 EF-G domain III/V-like CB4_RS18640 837394924108f2ee3f859287aa03fe8e 883 Pfam PF00027 Cyclic nucleotide-binding domain 28 113 3.9E-23 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS18640 837394924108f2ee3f859287aa03fe8e 883 Gene3D G3DSA:2.60.120.10 1 140 8.2E-33 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS18640 837394924108f2ee3f859287aa03fe8e 883 Pfam PF00939 Sodium:sulfate symporter transmembrane region 447 880 1.1E-26 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CB4_RS18640 837394924108f2ee3f859287aa03fe8e 883 PRINTS PR00103 cAMP-dependent protein kinase signature 86 97 2.0E-6 T 29-03-2018 CB4_RS18640 837394924108f2ee3f859287aa03fe8e 883 PRINTS PR00103 cAMP-dependent protein kinase signature 44 58 2.0E-6 T 29-03-2018 CB4_RS18640 837394924108f2ee3f859287aa03fe8e 883 PRINTS PR00103 cAMP-dependent protein kinase signature 74 83 2.0E-6 T 29-03-2018 CB4_RS18640 837394924108f2ee3f859287aa03fe8e 883 PRINTS PR00103 cAMP-dependent protein kinase signature 29 43 2.0E-6 T 29-03-2018 CB4_RS18640 837394924108f2ee3f859287aa03fe8e 883 SMART SM00100 8 129 3.6E-25 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS18640 837394924108f2ee3f859287aa03fe8e 883 SUPERFAMILY SSF51206 2 135 1.27E-33 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CB4_RS15965 22b6fead952aee4222ef99c9980f1ec7 175 Gene3D G3DSA:3.40.30.10 24 175 5.2E-36 T 29-03-2018 CB4_RS15965 22b6fead952aee4222ef99c9980f1ec7 175 ProSitePatterns PS00194 Thioredoxin family active site. 64 82 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CB4_RS15965 22b6fead952aee4222ef99c9980f1ec7 175 Pfam PF00578 AhpC/TSA family 37 152 1.3E-29 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS15965 22b6fead952aee4222ef99c9980f1ec7 175 SUPERFAMILY SSF52833 10 170 2.14E-38 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS04865 fa64e5c21d6d5571f33ca03aa6ecefb4 222 Gene3D G3DSA:3.40.50.300 1 219 1.1E-46 T 29-03-2018 CB4_RS04865 fa64e5c21d6d5571f33ca03aa6ecefb4 222 Pfam PF00005 ABC transporter 18 146 1.1E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS04865 fa64e5c21d6d5571f33ca03aa6ecefb4 222 SUPERFAMILY SSF52540 2 212 7.3E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS04865 fa64e5c21d6d5571f33ca03aa6ecefb4 222 SMART SM00382 26 196 1.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS02595 6ac8d3a294e8f6feeab1fd11ab7dc4da 229 Gene3D G3DSA:3.40.50.300 10 229 1.7E-65 T 29-03-2018 CB4_RS02595 6ac8d3a294e8f6feeab1fd11ab7dc4da 229 SUPERFAMILY SSF52540 12 227 1.13E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02595 6ac8d3a294e8f6feeab1fd11ab7dc4da 229 SMART SM00382 38 219 9.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS02595 6ac8d3a294e8f6feeab1fd11ab7dc4da 229 Pfam PF00005 ABC transporter 31 173 4.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS02595 6ac8d3a294e8f6feeab1fd11ab7dc4da 229 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS01595 7712f276b45811ab3c295824a7aa5f17 490 Gene3D G3DSA:3.40.640.10 6 278 9.8E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS01595 7712f276b45811ab3c295824a7aa5f17 490 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 7 298 2.1E-74 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CB4_RS01595 7712f276b45811ab3c295824a7aa5f17 490 SUPERFAMILY SSF55904 338 488 2.62E-26 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CB4_RS01595 7712f276b45811ab3c295824a7aa5f17 490 SUPERFAMILY SSF53383 7 380 2.79E-81 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS01595 7712f276b45811ab3c295824a7aa5f17 490 Gene3D G3DSA:3.90.1150.10 279 401 2.2E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS01595 7712f276b45811ab3c295824a7aa5f17 490 Gene3D G3DSA:3.90.100.10 404 489 1.3E-19 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CB4_RS01595 7712f276b45811ab3c295824a7aa5f17 490 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 412 464 3.3E-9 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CB4_RS08615 6bfb5f973099520f203c0e671b82fdf3 319 Gene3D G3DSA:3.40.366.10 186 313 2.3E-32 T 29-03-2018 CB4_RS08615 6bfb5f973099520f203c0e671b82fdf3 319 Gene3D G3DSA:3.40.366.10 3 140 3.6E-45 T 29-03-2018 CB4_RS08615 6bfb5f973099520f203c0e671b82fdf3 319 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 315 2.7E-36 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CB4_RS08615 6bfb5f973099520f203c0e671b82fdf3 319 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 5.5E-116 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CB4_RS08615 6bfb5f973099520f203c0e671b82fdf3 319 PIRSF PIRSF000446 1 312 2.3E-119 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CB4_RS08615 6bfb5f973099520f203c0e671b82fdf3 319 Gene3D G3DSA:3.30.70.250 141 185 5.2E-22 T 29-03-2018 CB4_RS08615 6bfb5f973099520f203c0e671b82fdf3 319 SUPERFAMILY SSF55048 129 194 4.71E-16 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CB4_RS08615 6bfb5f973099520f203c0e671b82fdf3 319 Pfam PF00698 Acyl transferase domain 6 295 3.5E-43 T 29-03-2018 IPR014043 Acyl transferase CB4_RS08615 6bfb5f973099520f203c0e671b82fdf3 319 SUPERFAMILY SSF52151 191 313 1.41E-78 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CB4_RS08615 6bfb5f973099520f203c0e671b82fdf3 319 SUPERFAMILY SSF52151 4 122 1.41E-78 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 Gene3D G3DSA:3.40.50.1260 179 380 6.1E-87 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 392 42.222 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 8.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 8.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 PRINTS PR00477 Phosphoglycerate kinase family signature 368 385 8.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 8.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 8.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 8.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 8.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 8.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 PRINTS PR00477 Phosphoglycerate kinase family signature 345 356 8.5E-98 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 Gene3D G3DSA:3.40.50.1260 3 178 2.0E-75 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 SUPERFAMILY SSF53748 1 392 2.24E-160 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 PIRSF PIRSF000724 1 393 2.6E-157 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03860 376ec780ef4ae9f03eb6bd17df012fa6 393 Pfam PF00162 Phosphoglycerate kinase 6 382 1.6E-163 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 SUPERFAMILY SSF58104 386 654 1.44E-75 T 29-03-2018 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 SUPERFAMILY SSF58104 319 353 1.44E-75 T 29-03-2018 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 Gene3D G3DSA:3.30.450.20 168 278 9.1E-17 T 29-03-2018 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 SMART SM00304 299 351 6.5E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 SMART SM00283 380 655 2.8E-84 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 Pfam PF02743 Cache domain 38 260 3.1E-27 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 SUPERFAMILY SSF103190 89 189 1.88E-13 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 478 505 4.3E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 430 4.3E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 507 536 4.3E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 428 608 1.1E-44 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 Gene3D G3DSA:1.10.287.950 311 407 1.7E-8 T 29-03-2018 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 Pfam PF00672 HAMP domain 300 348 8.4E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 Gene3D G3DSA:3.30.450.20 72 167 8.0E-20 T 29-03-2018 CB4_RS18250 97898335cddd7e084e84886c3bd7bc27 656 Gene3D G3DSA:1.10.287.950 408 656 4.5E-57 T 29-03-2018 CB4_RS05640 255ef43b27918561a5d3a26874d1b4a9 307 SUPERFAMILY SSF103481 41 143 3.14E-10 T 29-03-2018 CB4_RS05640 255ef43b27918561a5d3a26874d1b4a9 307 Pfam PF00892 EamA-like transporter family 149 287 1.1E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS05640 255ef43b27918561a5d3a26874d1b4a9 307 Pfam PF00892 EamA-like transporter family 8 140 2.2E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS05640 255ef43b27918561a5d3a26874d1b4a9 307 SUPERFAMILY SSF103481 207 289 1.27E-11 T 29-03-2018 CB4_RS05950 3ccdd2c7f9121bdba0aa0c4ae288ef79 468 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 146 456 2.8E-74 T 29-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CB4_RS05950 3ccdd2c7f9121bdba0aa0c4ae288ef79 468 Pfam PF08486 Stage II sporulation protein 143 226 4.0E-25 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CB4_RS19675 ef6ca3acc9e20dc5c75a392c945c4718 468 SUPERFAMILY SSF53335 80 462 2.0E-87 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS19675 ef6ca3acc9e20dc5c75a392c945c4718 468 Gene3D G3DSA:2.40.50.140 5 86 5.9E-22 T 29-03-2018 CB4_RS19675 ef6ca3acc9e20dc5c75a392c945c4718 468 Pfam PF01938 TRAM domain 16 68 3.6E-13 T 29-03-2018 IPR002792 TRAM domain CB4_RS19675 ef6ca3acc9e20dc5c75a392c945c4718 468 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 284 462 1.7E-20 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CB4_RS19675 ef6ca3acc9e20dc5c75a392c945c4718 468 SUPERFAMILY SSF50249 12 69 6.28E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS19675 ef6ca3acc9e20dc5c75a392c945c4718 468 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 394 425 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site CB4_RS19675 ef6ca3acc9e20dc5c75a392c945c4718 468 Gene3D G3DSA:3.40.50.150 160 461 2.8E-52 T 29-03-2018 CB4_RS19675 ef6ca3acc9e20dc5c75a392c945c4718 468 Gene3D G3DSA:3.40.50.150 87 151 2.7E-10 T 29-03-2018 CB4_RS19675 ef6ca3acc9e20dc5c75a392c945c4718 468 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 29 455 2.7E-163 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CB4_RS08465 df209b7d784c133e99ae8d974d0c392e 205 SMART SM00072 5 187 8.9E-67 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CB4_RS08465 df209b7d784c133e99ae8d974d0c392e 205 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CB4_RS08465 df209b7d784c133e99ae8d974d0c392e 205 Gene3D G3DSA:3.30.63.10 52 83 9.3E-24 T 29-03-2018 CB4_RS08465 df209b7d784c133e99ae8d974d0c392e 205 Hamap MF_00328 Guanylate kinase [gmk]. 4 187 36.812 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CB4_RS08465 df209b7d784c133e99ae8d974d0c392e 205 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 184 3.2E-73 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CB4_RS08465 df209b7d784c133e99ae8d974d0c392e 205 Gene3D G3DSA:3.40.50.300 1 51 5.1E-11 T 29-03-2018 CB4_RS08465 df209b7d784c133e99ae8d974d0c392e 205 Pfam PF00625 Guanylate kinase 8 184 2.3E-48 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CB4_RS08465 df209b7d784c133e99ae8d974d0c392e 205 Gene3D G3DSA:3.40.50.300 84 187 4.4E-31 T 29-03-2018 CB4_RS08465 df209b7d784c133e99ae8d974d0c392e 205 SUPERFAMILY SSF52540 3 189 3.11E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02400 4c57ef313990a19debfcd9584cc00d14 435 PIRSF PIRSF006060 1 434 6.2E-82 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS02400 4c57ef313990a19debfcd9584cc00d14 435 Pfam PF13520 Amino acid permease 10 407 1.0E-60 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS02400 4c57ef313990a19debfcd9584cc00d14 435 Gene3D G3DSA:1.10.287.70 12 378 0.068 T 29-03-2018 CB4_RS17930 275ddf061d7949346203933387e1781f 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 372 1.5E-45 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS17930 275ddf061d7949346203933387e1781f 402 Gene3D G3DSA:1.20.140.10 218 390 5.6E-55 T 29-03-2018 CB4_RS17930 275ddf061d7949346203933387e1781f 402 SUPERFAMILY SSF47203 227 384 2.42E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS17930 275ddf061d7949346203933387e1781f 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.3E-38 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS17930 275ddf061d7949346203933387e1781f 402 SUPERFAMILY SSF56645 1 242 1.7E-90 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CB4_RS17930 275ddf061d7949346203933387e1781f 402 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS17930 275ddf061d7949346203933387e1781f 402 PIRSF PIRSF016578 6 99 0.0042 T 29-03-2018 CB4_RS17930 275ddf061d7949346203933387e1781f 402 PIRSF PIRSF016578 123 387 2.8E-9 T 29-03-2018 CB4_RS17930 275ddf061d7949346203933387e1781f 402 Gene3D G3DSA:1.10.540.10 1 120 2.0E-39 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS17930 275ddf061d7949346203933387e1781f 402 Gene3D G3DSA:2.40.110.10 121 217 4.1E-41 T 29-03-2018 CB4_RS17930 275ddf061d7949346203933387e1781f 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 2.9E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 Pfam PF01926 50S ribosome-binding GTPase 6 121 8.0E-28 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 Pfam PF01926 50S ribosome-binding GTPase 178 296 1.8E-27 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 SUPERFAMILY SSF52540 139 436 9.57E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 PIRSF PIRSF006485 2 439 8.6E-179 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 SMART SM00382 175 312 7.7 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 SMART SM00382 2 137 0.059 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 434 1.8E-181 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 Gene3D G3DSA:1.20.120.430 1 71 2.7E-20 T 29-03-2018 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 Gene3D G3DSA:1.20.120.430 243 358 1.6E-15 T 29-03-2018 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 Gene3D G3DSA:1.20.120.430 72 242 5.1E-45 T 29-03-2018 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 3.7E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 74 92 3.7E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 354 434 3.6E-34 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 Gene3D G3DSA:3.30.300.20 359 435 5.8E-36 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 SUPERFAMILY SSF52540 4 169 2.09E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 Hamap MF_00195 GTPase Der [der]. 3 437 41.64 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 177 340 7.9E-24 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS15235 fc68c99263be8e95796ee4c76b213184 439 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 132 1.3E-25 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS00630 d2a37d6096183f3d083174a6598b0b86 187 Gene3D G3DSA:1.10.10.10 95 186 2.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00630 d2a37d6096183f3d083174a6598b0b86 187 Pfam PF08281 Sigma-70, region 4 129 180 3.2E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS00630 d2a37d6096183f3d083174a6598b0b86 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 184 2.2E-37 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS00630 d2a37d6096183f3d083174a6598b0b86 187 Gene3D G3DSA:1.10.1740.10 2 94 8.8E-30 T 29-03-2018 CB4_RS00630 d2a37d6096183f3d083174a6598b0b86 187 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 45 76 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS00630 d2a37d6096183f3d083174a6598b0b86 187 SUPERFAMILY SSF88946 4 95 1.08E-31 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS00630 d2a37d6096183f3d083174a6598b0b86 187 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 2 185 2.9E-78 T 29-03-2018 IPR014294 RNA polymerase sigma-W, bacillaceae CB4_RS00630 d2a37d6096183f3d083174a6598b0b86 187 Pfam PF04542 Sigma-70 region 2 23 89 1.6E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS00630 d2a37d6096183f3d083174a6598b0b86 187 SUPERFAMILY SSF88659 99 185 4.86E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS01080 0dd0bf90fb9a86f9c8b071ab53e4fe79 216 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 183 3.5E-39 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR01159 DNA gyrase subunit B signature 316 332 1.6E-80 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR01159 DNA gyrase subunit B signature 591 603 1.6E-80 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR01159 DNA gyrase subunit B signature 9 19 1.6E-80 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR01159 DNA gyrase subunit B signature 364 378 1.6E-80 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR01159 DNA gyrase subunit B signature 184 199 1.6E-80 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR01159 DNA gyrase subunit B signature 199 212 1.6E-80 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR01159 DNA gyrase subunit B signature 378 398 1.6E-80 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR01159 DNA gyrase subunit B signature 607 623 1.6E-80 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR01159 DNA gyrase subunit B signature 224 246 1.6E-80 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR01159 DNA gyrase subunit B signature 474 483 1.6E-80 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 Gene3D G3DSA:3.40.50.670 405 635 5.3E-106 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 Gene3D G3DSA:3.30.565.10 21 224 9.3E-76 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 9 638 0.0 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 SMART SM00387 34 178 2.4E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 Pfam PF00204 DNA gyrase B 225 394 2.4E-66 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 Gene3D G3DSA:3.30.230.10 225 396 1.5E-68 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 SUPERFAMILY SSF54211 225 395 2.85E-64 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 SUPERFAMILY SSF56719 398 631 1.54E-91 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 6 638 96.777 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 SUPERFAMILY SSF55874 9 216 1.31E-72 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 Pfam PF01751 Toprim domain 423 534 5.9E-19 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 SMART SM00433 38 631 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 36 177 6.3E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR00418 DNA topoisomerase II family signature 73 86 9.4E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR00418 DNA topoisomerase II family signature 116 130 9.4E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR00418 DNA topoisomerase II family signature 508 525 9.4E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR00418 DNA topoisomerase II family signature 424 438 9.4E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR00418 DNA topoisomerase II family signature 490 506 9.4E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR00418 DNA topoisomerase II family signature 38 53 9.4E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR00418 DNA topoisomerase II family signature 570 586 9.4E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR00418 DNA topoisomerase II family signature 272 285 9.4E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 PRINTS PR00418 DNA topoisomerase II family signature 528 540 9.4E-73 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS01885 bf3b47e01d8bb0a45233de853d0a51be 638 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 567 627 2.0E-31 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CB4_RS07745 2673cceeb79bc18fa5defd579b60b731 113 Gene3D G3DSA:2.30.30.40 45 112 2.7E-38 T 29-03-2018 CB4_RS07745 2673cceeb79bc18fa5defd579b60b731 113 Pfam PF03831 PhnA domain 46 113 9.5E-35 T 29-03-2018 IPR013988 PhnA protein, C-terminal CB4_RS07745 2673cceeb79bc18fa5defd579b60b731 113 Pfam PF08274 PhnA Zinc-Ribbon 4 32 7.5E-17 T 29-03-2018 IPR013987 PhnA protein, N-terminal CB4_RS07745 2673cceeb79bc18fa5defd579b60b731 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 112 4.4E-52 T 29-03-2018 IPR004624 PhnA protein CB4_RS07745 2673cceeb79bc18fa5defd579b60b731 113 Gene3D G3DSA:2.20.25.10 2 40 2.4E-17 T 29-03-2018 CB4_RS07745 2673cceeb79bc18fa5defd579b60b731 113 SUPERFAMILY SSF57783 3 35 1.0E-14 T 29-03-2018 CB4_RS07745 2673cceeb79bc18fa5defd579b60b731 113 SUPERFAMILY SSF82057 41 113 5.04E-30 T 29-03-2018 CB4_RS02305 055696dabd78e669701ef9e11cdc8056 224 Pfam PF07729 FCD domain 86 211 1.0E-20 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS02305 055696dabd78e669701ef9e11cdc8056 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 68 1.3E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS02305 055696dabd78e669701ef9e11cdc8056 224 SMART SM00345 19 76 8.3E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS02305 055696dabd78e669701ef9e11cdc8056 224 SUPERFAMILY SSF46785 8 85 1.58E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02305 055696dabd78e669701ef9e11cdc8056 224 SMART SM00895 86 211 3.4E-18 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS02305 055696dabd78e669701ef9e11cdc8056 224 Gene3D G3DSA:1.10.10.10 1 84 7.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02305 055696dabd78e669701ef9e11cdc8056 224 Gene3D G3DSA:1.20.120.530 85 224 1.1E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS02305 055696dabd78e669701ef9e11cdc8056 224 SUPERFAMILY SSF48008 82 219 1.18E-26 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS02305 055696dabd78e669701ef9e11cdc8056 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 7.4E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS02305 055696dabd78e669701ef9e11cdc8056 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 7.4E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS09055 0524bd45c5438327951783f21922a525 300 SUPERFAMILY SSF56349 8 294 3.83E-53 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS09055 0524bd45c5438327951783f21922a525 300 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 13 92 2.4E-21 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CB4_RS09055 0524bd45c5438327951783f21922a525 300 Gene3D G3DSA:1.10.443.10 114 294 1.7E-44 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS09055 0524bd45c5438327951783f21922a525 300 Pfam PF00589 Phage integrase family 115 285 3.3E-49 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS09055 0524bd45c5438327951783f21922a525 300 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 8 300 55.684 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CB4_RS09055 0524bd45c5438327951783f21922a525 300 Gene3D G3DSA:1.10.150.130 7 113 1.9E-24 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CB4_RS09055 0524bd45c5438327951783f21922a525 300 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 13 300 9.7E-105 T 29-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CB4_RS05530 25ee11ad3e37e2301243621620b9be04 369 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 9 354 3.7E-139 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CB4_RS05530 25ee11ad3e37e2301243621620b9be04 369 Gene3D G3DSA:3.40.50.1820 17 361 1.0E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS05530 25ee11ad3e37e2301243621620b9be04 369 Pfam PF00561 alpha/beta hydrolase fold 37 342 8.5E-29 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS05530 25ee11ad3e37e2301243621620b9be04 369 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 1 356 44.535 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CB4_RS05530 25ee11ad3e37e2301243621620b9be04 369 PIRSF PIRSF000443 2 364 4.0E-138 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CB4_RS05530 25ee11ad3e37e2301243621620b9be04 369 SUPERFAMILY SSF53474 6 356 5.75E-102 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS11875 77e742c5025b9cfc2eb7c7d11fd0a086 454 Pfam PF04545 Sigma-70, region 4 141 186 5.0E-6 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11875 77e742c5025b9cfc2eb7c7d11fd0a086 454 Gene3D G3DSA:1.10.10.10 119 226 3.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS11875 77e742c5025b9cfc2eb7c7d11fd0a086 454 SUPERFAMILY SSF88659 106 193 1.61E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11875 77e742c5025b9cfc2eb7c7d11fd0a086 454 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 190 1.9E-27 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11875 77e742c5025b9cfc2eb7c7d11fd0a086 454 Gene3D G3DSA:1.10.1660.10 346 439 1.3E-5 T 29-03-2018 CB4_RS11875 77e742c5025b9cfc2eb7c7d11fd0a086 454 Pfam PF04542 Sigma-70 region 2 21 90 5.3E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS11875 77e742c5025b9cfc2eb7c7d11fd0a086 454 Gene3D G3DSA:1.10.1740.10 5 88 9.1E-21 T 29-03-2018 CB4_RS11875 77e742c5025b9cfc2eb7c7d11fd0a086 454 Gene3D G3DSA:1.10.10.60 308 345 0.13 T 29-03-2018 CB4_RS11875 77e742c5025b9cfc2eb7c7d11fd0a086 454 SUPERFAMILY SSF88946 4 89 5.23E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS14005 1a10e35416a7a1777d7a41598e69b8fd 74 Gene3D G3DSA:1.10.287.540 4 57 9.6E-21 T 29-03-2018 CB4_RS14005 1a10e35416a7a1777d7a41598e69b8fd 74 SUPERFAMILY SSF158221 1 43 5.89E-11 T 29-03-2018 CB4_RS14005 1a10e35416a7a1777d7a41598e69b8fd 74 Hamap MF_01103 UPF0291 protein . 2 61 12.921 T 29-03-2018 IPR009242 Protein of unknown function DUF896 CB4_RS14005 1a10e35416a7a1777d7a41598e69b8fd 74 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 65 3.0E-22 T 29-03-2018 IPR009242 Protein of unknown function DUF896 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 SMART SM00304 189 241 5.1E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 SMART SM00388 363 430 2.6E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 SUPERFAMILY SSF55874 420 587 2.88E-51 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 244 362 1.0E-7 T 29-03-2018 IPR000014 PAS domain CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 Gene3D G3DSA:3.30.450.20 29 163 9.1E-25 T 29-03-2018 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 SUPERFAMILY SSF103190 35 164 5.89E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 527 5.2E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 566 5.2E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 541 5.2E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 572 585 5.2E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 Gene3D G3DSA:1.10.287.130 369 424 2.1E-20 T 29-03-2018 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 SMART SM00387 475 588 9.1E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 SUPERFAMILY SSF158472 189 239 7.72E-9 T 29-03-2018 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 Gene3D G3DSA:3.30.450.20 245 368 3.2E-19 T 29-03-2018 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 475 587 6.9E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 SUPERFAMILY SSF47384 348 431 2.55E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 Gene3D G3DSA:3.30.565.10 425 588 8.0E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 Pfam PF00672 HAMP domain 189 237 3.1E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 Pfam PF00512 His Kinase A (phospho-acceptor) domain 363 429 1.4E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 SUPERFAMILY SSF55785 238 350 7.42E-11 T 29-03-2018 IPR000014 PAS domain CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 Pfam PF08448 PAS fold 254 358 4.7E-7 T 29-03-2018 IPR013656 PAS fold-4 CB4_RS18375 8910148b7d945d8db4981e11ebf462ec 592 Pfam PF16736 Single Cache-like 34 152 6.0E-12 T 29-03-2018 IPR031967 PhoR, single Cache-like domain CB4_RS16530 a9ad7adbc9f4a990976ac3b7039d3857 496 Gene3D G3DSA:3.40.605.10 11 281 3.3E-116 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS16530 a9ad7adbc9f4a990976ac3b7039d3857 496 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CB4_RS16530 a9ad7adbc9f4a990976ac3b7039d3857 496 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CB4_RS16530 a9ad7adbc9f4a990976ac3b7039d3857 496 SUPERFAMILY SSF53720 19 494 1.96E-186 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS16530 a9ad7adbc9f4a990976ac3b7039d3857 496 Gene3D G3DSA:3.40.309.10 282 477 6.2E-77 T 29-03-2018 CB4_RS16530 a9ad7adbc9f4a990976ac3b7039d3857 496 Pfam PF00171 Aldehyde dehydrogenase family 28 491 5.7E-194 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS09790 c1aa8320526b217df6739897d7c98110 343 Pfam PF00268 Ribonucleotide reductase, small chain 28 300 3.7E-70 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09790 c1aa8320526b217df6739897d7c98110 343 SUPERFAMILY SSF47240 18 343 1.73E-81 T 29-03-2018 IPR009078 Ferritin-like superfamily CB4_RS09790 c1aa8320526b217df6739897d7c98110 343 PIRSF PIRSF000355 1 343 2.8E-108 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09790 c1aa8320526b217df6739897d7c98110 343 Gene3D G3DSA:1.10.620.20 1 318 3.1E-79 T 29-03-2018 CB4_RS15755 27d6e9e6f53dedac801affc11df884bf 120 Gene3D G3DSA:3.30.750.24 1 108 1.5E-15 T 29-03-2018 IPR002645 STAS domain CB4_RS15755 27d6e9e6f53dedac801affc11df884bf 120 Pfam PF01740 STAS domain 6 105 9.4E-13 T 29-03-2018 IPR002645 STAS domain CB4_RS15755 27d6e9e6f53dedac801affc11df884bf 120 SUPERFAMILY SSF52091 5 97 6.28E-14 T 29-03-2018 IPR002645 STAS domain CB4_RS16460 94a9082041914eba95896a9a6401b5d2 227 Pfam PF13411 MerR HTH family regulatory protein 8 75 1.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS16460 94a9082041914eba95896a9a6401b5d2 227 SUPERFAMILY SSF46955 6 67 9.16E-8 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS16460 94a9082041914eba95896a9a6401b5d2 227 Gene3D G3DSA:1.10.1660.10 1 213 2.6E-15 T 29-03-2018 CB4_RS06415 bda4a140a4e70a6c5149afc9ac149599 476 Pfam PF01593 Flavin containing amine oxidoreductase 14 464 3.1E-61 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CB4_RS06415 bda4a140a4e70a6c5149afc9ac149599 476 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 4 469 8.4E-127 T 29-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CB4_RS06415 bda4a140a4e70a6c5149afc9ac149599 476 SUPERFAMILY SSF51905 7 323 5.34E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS06415 bda4a140a4e70a6c5149afc9ac149599 476 SUPERFAMILY SSF51905 433 464 5.34E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS06415 bda4a140a4e70a6c5149afc9ac149599 476 Gene3D G3DSA:3.90.660.20 220 415 3.9E-41 T 29-03-2018 CB4_RS06415 bda4a140a4e70a6c5149afc9ac149599 476 SUPERFAMILY SSF54373 308 415 2.55E-30 T 29-03-2018 CB4_RS06415 bda4a140a4e70a6c5149afc9ac149599 476 Gene3D G3DSA:3.90.660.20 43 115 9.7E-9 T 29-03-2018 CB4_RS06415 bda4a140a4e70a6c5149afc9ac149599 476 Gene3D G3DSA:1.10.3110.10 116 211 2.0E-31 T 29-03-2018 CB4_RS08110 5d7f07c77106174f8857474316a6173b 132 SUPERFAMILY SSF56276 5 116 2.16E-40 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CB4_RS08110 5d7f07c77106174f8857474316a6173b 132 Gene3D G3DSA:3.60.90.10 1 124 1.5E-43 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CB4_RS08110 5d7f07c77106174f8857474316a6173b 132 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 5 115 7.9E-43 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CB4_RS08110 5d7f07c77106174f8857474316a6173b 132 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 3 119 29.561 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CB4_RS08110 5d7f07c77106174f8857474316a6173b 132 Pfam PF02675 S-adenosylmethionine decarboxylase 9 115 5.8E-37 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CB4_RS10870 17b8931bf97f73fc421e5cc10102e7dd 149 Gene3D G3DSA:3.10.129.10 6 148 6.7E-27 T 29-03-2018 CB4_RS10870 17b8931bf97f73fc421e5cc10102e7dd 149 Pfam PF13452 N-terminal half of MaoC dehydratase 11 140 8.2E-32 T 29-03-2018 CB4_RS10870 17b8931bf97f73fc421e5cc10102e7dd 149 SUPERFAMILY SSF54637 11 146 6.78E-28 T 29-03-2018 IPR029069 HotDog domain CB4_RS10870 17b8931bf97f73fc421e5cc10102e7dd 149 PIRSF PIRSF018072 5 149 8.2E-34 T 29-03-2018 IPR016709 Uncharacterised protein family UPF0336 CB4_RS19860 fb0af642e933399a566fef6c522f67b8 141 Gene3D G3DSA:2.60.40.420 6 141 5.3E-20 T 29-03-2018 IPR008972 Cupredoxin CB4_RS19860 fb0af642e933399a566fef6c522f67b8 141 Pfam PF13473 Cupredoxin-like domain 46 140 8.6E-9 T 29-03-2018 IPR028096 EfeO-type cupredoxin-like domain CB4_RS19860 fb0af642e933399a566fef6c522f67b8 141 SUPERFAMILY SSF49503 49 141 1.42E-18 T 29-03-2018 IPR008972 Cupredoxin CB4_RS05090 f900556ccc8e413934269e7c21d16c73 251 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 35 144 2.1E-11 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS05090 f900556ccc8e413934269e7c21d16c73 251 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 148 243 7.0E-27 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS05090 f900556ccc8e413934269e7c21d16c73 251 SUPERFAMILY SSF51735 31 145 4.73E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS05090 f900556ccc8e413934269e7c21d16c73 251 Gene3D G3DSA:1.10.1040.10 148 248 8.9E-31 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CB4_RS05090 f900556ccc8e413934269e7c21d16c73 251 SUPERFAMILY SSF48179 147 247 6.55E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS05090 f900556ccc8e413934269e7c21d16c73 251 Gene3D G3DSA:3.40.50.720 4 147 4.0E-13 T 29-03-2018 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 SUPERFAMILY SSF53706 12 565 8.51E-167 T 29-03-2018 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 Gene3D G3DSA:2.20.25.90 2 68 5.5E-17 T 29-03-2018 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 417 434 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 Gene3D G3DSA:2.40.40.20 551 680 2.8E-26 T 29-03-2018 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 Gene3D G3DSA:3.40.228.10 374 522 7.5E-8 T 29-03-2018 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 Pfam PF01568 Molydopterin dinucleotide binding domain 566 668 2.2E-18 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 12 63 9.1E-13 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 Pfam PF00384 Molybdopterin oxidoreductase 67 473 2.4E-66 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 Gene3D G3DSA:3.40.228.10 155 373 5.5E-64 T 29-03-2018 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 SUPERFAMILY SSF50692 560 679 5.2E-29 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 SMART SM00926 9 64 2.8E-14 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS13900 2df6798957a1d66e547c532b7453c843 680 Gene3D G3DSA:3.40.50.740 69 154 1.7E-18 T 29-03-2018 CB4_RS17040 c9ce987285c02c19afee982cd8b18aee 356 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 38 342 1.2E-117 T 29-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CB4_RS17040 c9ce987285c02c19afee982cd8b18aee 356 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 11 342 4.9E-139 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CB4_RS17040 c9ce987285c02c19afee982cd8b18aee 356 Pfam PF01008 Initiation factor 2 subunit family 52 341 3.1E-87 T 29-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CB4_RS17040 c9ce987285c02c19afee982cd8b18aee 356 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 9 353 40.097 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CB4_RS17040 c9ce987285c02c19afee982cd8b18aee 356 Gene3D G3DSA:1.20.120.420 10 153 1.6E-55 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CB4_RS17040 c9ce987285c02c19afee982cd8b18aee 356 Gene3D G3DSA:3.40.50.10470 154 356 3.6E-68 T 29-03-2018 CB4_RS17040 c9ce987285c02c19afee982cd8b18aee 356 SUPERFAMILY SSF100950 4 351 6.84E-125 T 29-03-2018 CB4_RS09635 085a7963a5adb86cf86fdcde705f1109 561 SMART SM00487 102 292 9.9E-8 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS09635 085a7963a5adb86cf86fdcde705f1109 561 SUPERFAMILY SSF52540 71 308 5.32E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09635 085a7963a5adb86cf86fdcde705f1109 561 Pfam PF00176 SNF2 family N-terminal domain 122 343 5.5E-26 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CB4_RS09635 085a7963a5adb86cf86fdcde705f1109 561 Gene3D G3DSA:3.40.50.10810 107 391 1.0E-29 T 29-03-2018 CB4_RS09635 085a7963a5adb86cf86fdcde705f1109 561 SMART SM00490 413 496 0.0013 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS09635 085a7963a5adb86cf86fdcde705f1109 561 Gene3D G3DSA:3.40.50.300 392 536 1.2E-20 T 29-03-2018 CB4_RS09635 085a7963a5adb86cf86fdcde705f1109 561 SUPERFAMILY SSF52540 310 541 4.71E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09635 085a7963a5adb86cf86fdcde705f1109 561 Pfam PF00271 Helicase conserved C-terminal domain 389 496 4.3E-9 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS08880 434de9fdd568cd85420e57f7ad57b0ba 119 Gene3D G3DSA:3.40.1800.10 22 109 2.3E-8 T 29-03-2018 CB4_RS08880 434de9fdd568cd85420e57f7ad57b0ba 119 SMART SM00507 31 88 4.7E-5 T 29-03-2018 IPR003615 HNH nuclease CB4_RS08880 434de9fdd568cd85420e57f7ad57b0ba 119 Pfam PF01844 HNH endonuclease 44 92 5.5E-10 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 Pfam PF13492 GAF domain 463 587 6.5E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 Gene3D G3DSA:3.30.450.40 301 348 0.11 T 29-03-2018 IPR029016 GAF domain-like CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 Gene3D G3DSA:3.30.450.40 349 441 1.9E-10 T 29-03-2018 IPR029016 GAF domain-like CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 SMART SM00267 593 757 5.6E-52 T 29-03-2018 IPR000160 GGDEF domain CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 Gene3D G3DSA:3.30.450.40 132 300 1.9E-13 T 29-03-2018 IPR029016 GAF domain-like CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 Gene3D G3DSA:3.30.450.40 444 601 1.9E-18 T 29-03-2018 IPR029016 GAF domain-like CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 601 755 8.7E-39 T 29-03-2018 IPR000160 GGDEF domain CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 Gene3D G3DSA:3.30.70.270 602 762 1.5E-46 T 29-03-2018 CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 Pfam PF00990 Diguanylate cyclase, GGDEF domain 605 753 1.6E-39 T 29-03-2018 IPR000160 GGDEF domain CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 SMART SM00065 462 601 8.1E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 SMART SM00065 152 299 0.011 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 SUPERFAMILY SSF55781 427 591 5.45E-18 T 29-03-2018 IPR029016 GAF domain-like CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 SUPERFAMILY SSF55781 304 457 5.02E-13 T 29-03-2018 IPR029016 GAF domain-like CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 SUPERFAMILY SSF55073 609 756 7.85E-41 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS17230 07d868f335870a2b2e90c8a12ceb1053 762 SUPERFAMILY SSF55781 135 295 6.11E-11 T 29-03-2018 IPR029016 GAF domain-like CB4_RS11250 f892e9fb3c20bab63afae8798f10338a 372 Gene3D G3DSA:3.10.450.40 53 110 0.0017 T 29-03-2018 CB4_RS11250 f892e9fb3c20bab63afae8798f10338a 372 Gene3D G3DSA:1.20.950.20 114 226 0.011 T 29-03-2018 CB4_RS11250 f892e9fb3c20bab63afae8798f10338a 372 Pfam PF03929 PepSY-associated TM region 7 355 4.2E-66 T 29-03-2018 IPR005625 PepSY-associated TM protein CB4_RS11250 f892e9fb3c20bab63afae8798f10338a 372 Pfam PF03413 Peptidase propeptide and YPEB domain 53 108 6.7E-6 T 29-03-2018 IPR025711 PepSY domain CB4_RS01895 edaac0e54dc8fda112d602b5438d7962 371 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CB4_RS01895 edaac0e54dc8fda112d602b5438d7962 371 SUPERFAMILY SSF52540 243 344 1.49E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01895 edaac0e54dc8fda112d602b5438d7962 371 SUPERFAMILY SSF52540 2 216 1.49E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01895 edaac0e54dc8fda112d602b5438d7962 371 Gene3D G3DSA:3.40.50.300 2 370 8.8E-28 T 29-03-2018 CB4_RS01895 edaac0e54dc8fda112d602b5438d7962 371 ProSitePatterns PS00618 RecF protein signature 2. 311 329 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CB4_RS01895 edaac0e54dc8fda112d602b5438d7962 371 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 366 1.4E-120 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CB4_RS01895 edaac0e54dc8fda112d602b5438d7962 371 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 371 97.97 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CB4_RS01895 edaac0e54dc8fda112d602b5438d7962 371 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 361 6.5E-18 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 ProSitePatterns PS00042 Crp-type HTH domain signature. 180 203 - T 29-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 Pfam PF00027 Cyclic nucleotide-binding domain 34 121 2.0E-21 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 178 194 3.9E-9 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 194 209 3.9E-9 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 Gene3D G3DSA:2.60.120.10 5 148 1.4E-32 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 SUPERFAMILY SSF51206 9 145 2.88E-37 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 SUPERFAMILY SSF46785 150 221 1.15E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 Pfam PF13545 Crp-like helix-turn-helix domain 153 218 6.0E-17 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 SMART SM00419 172 220 3.3E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 Gene3D G3DSA:1.10.10.10 149 223 2.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16970 331c8fc78671a579decac27de40bd62a 226 SMART SM00100 15 133 3.8E-25 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS13030 0d7374790c795fe1c3ee34bd7569232d 375 Gene3D G3DSA:3.50.50.60 21 143 2.3E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS13030 0d7374790c795fe1c3ee34bd7569232d 375 SUPERFAMILY SSF51905 21 318 5.03E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS13030 0d7374790c795fe1c3ee34bd7569232d 375 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 5.3E-5 T 29-03-2018 CB4_RS13030 0d7374790c795fe1c3ee34bd7569232d 375 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 24 43 5.3E-5 T 29-03-2018 CB4_RS13030 0d7374790c795fe1c3ee34bd7569232d 375 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 22 309 3.4E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS13030 0d7374790c795fe1c3ee34bd7569232d 375 Gene3D G3DSA:3.50.50.60 144 172 6.3E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS13030 0d7374790c795fe1c3ee34bd7569232d 375 Gene3D G3DSA:3.50.50.60 173 330 6.9E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS18280 4b80c48257b0ed52b143c07a158c6be1 295 Pfam PF08812 YtxC-like family 79 280 6.2E-26 T 29-03-2018 IPR014199 Sporulation protein YtxC CB4_RS07880 178a9766c431c23732adea17bef7c496 185 SMART SM00841 129 184 6.6E-33 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CB4_RS07880 178a9766c431c23732adea17bef7c496 185 Gene3D G3DSA:2.40.50.140 64 127 2.8E-24 T 29-03-2018 CB4_RS07880 178a9766c431c23732adea17bef7c496 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 49.946 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CB4_RS07880 178a9766c431c23732adea17bef7c496 185 Gene3D G3DSA:2.30.30.30 2 61 2.7E-27 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CB4_RS07880 178a9766c431c23732adea17bef7c496 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 9.1E-26 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CB4_RS07880 178a9766c431c23732adea17bef7c496 185 PIRSF PIRSF005901 1 185 3.4E-71 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP CB4_RS07880 178a9766c431c23732adea17bef7c496 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.4E-28 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like CB4_RS07880 178a9766c431c23732adea17bef7c496 185 SMART SM01185 67 121 5.4E-27 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CB4_RS07880 178a9766c431c23732adea17bef7c496 185 SUPERFAMILY SSF50104 1 62 2.83E-22 T 29-03-2018 IPR008991 Translation protein SH3-like domain CB4_RS07880 178a9766c431c23732adea17bef7c496 185 Gene3D G3DSA:2.40.50.140 129 184 1.7E-26 T 29-03-2018 CB4_RS07880 178a9766c431c23732adea17bef7c496 185 SUPERFAMILY SSF50249 129 185 3.43E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS07880 178a9766c431c23732adea17bef7c496 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.5E-79 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CB4_RS07880 178a9766c431c23732adea17bef7c496 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CB4_RS07880 178a9766c431c23732adea17bef7c496 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 9.4E-23 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CB4_RS07880 178a9766c431c23732adea17bef7c496 185 SUPERFAMILY SSF50249 65 129 4.8E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS19370 c602b425dbd3d4193383705abbe9b6f2 278 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 241 4.8E-98 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CB4_RS19370 c602b425dbd3d4193383705abbe9b6f2 278 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 217 4.6E-47 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS19370 c602b425dbd3d4193383705abbe9b6f2 278 SUPERFAMILY SSF53790 2 251 6.54E-83 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS19370 c602b425dbd3d4193383705abbe9b6f2 278 Gene3D G3DSA:3.30.950.10 129 260 4.3E-42 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS19370 c602b425dbd3d4193383705abbe9b6f2 278 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CB4_RS19370 c602b425dbd3d4193383705abbe9b6f2 278 Gene3D G3DSA:3.40.1010.10 3 128 1.8E-38 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS10615 fd4352be915628af08cc86e722628f4b 303 SUPERFAMILY SSF51730 37 298 1.37E-73 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CB4_RS10615 fd4352be915628af08cc86e722628f4b 303 Gene3D G3DSA:3.20.20.220 10 302 3.2E-70 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CB4_RS10615 fd4352be915628af08cc86e722628f4b 303 Pfam PF01619 Proline dehydrogenase 45 296 4.6E-31 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CB4_RS10615 fd4352be915628af08cc86e722628f4b 303 PIRSF PIRSF000196 3 303 3.7E-130 T 29-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CB4_RS15730 5909bea8ae8db85bfc6725d50b22ac54 354 SUPERFAMILY SSF55781 27 169 1.67E-6 T 29-03-2018 IPR029016 GAF domain-like CB4_RS15730 5909bea8ae8db85bfc6725d50b22ac54 354 SUPERFAMILY SSF46894 283 348 2.04E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS15730 5909bea8ae8db85bfc6725d50b22ac54 354 Gene3D G3DSA:1.10.10.10 176 352 9.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15730 5909bea8ae8db85bfc6725d50b22ac54 354 SMART SM00421 290 347 7.0E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS15730 5909bea8ae8db85bfc6725d50b22ac54 354 Pfam PF00196 Bacterial regulatory proteins, luxR family 293 344 4.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS15730 5909bea8ae8db85bfc6725d50b22ac54 354 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 307 323 2.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS15730 5909bea8ae8db85bfc6725d50b22ac54 354 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 293 307 2.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS15730 5909bea8ae8db85bfc6725d50b22ac54 354 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 323 335 2.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS15730 5909bea8ae8db85bfc6725d50b22ac54 354 Gene3D G3DSA:3.30.450.40 24 173 6.0E-8 T 29-03-2018 IPR029016 GAF domain-like CB4_RS07335 500ec1b4d76d6d3942aea464d67d7e02 293 Pfam PF12801 4Fe-4S binding domain 170 203 9.7E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS07335 500ec1b4d76d6d3942aea464d67d7e02 293 Pfam PF12801 4Fe-4S binding domain 120 142 28.0 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS07335 500ec1b4d76d6d3942aea464d67d7e02 293 Pfam PF12801 4Fe-4S binding domain 64 106 3.7E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS07335 500ec1b4d76d6d3942aea464d67d7e02 293 Pfam PF12838 4Fe-4S dicluster domain 218 265 7.3E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS07335 500ec1b4d76d6d3942aea464d67d7e02 293 Gene3D G3DSA:3.30.70.20 254 287 3.5E-5 T 29-03-2018 CB4_RS07335 500ec1b4d76d6d3942aea464d67d7e02 293 SUPERFAMILY SSF54862 71 93 4.19E-18 T 29-03-2018 CB4_RS07335 500ec1b4d76d6d3942aea464d67d7e02 293 SUPERFAMILY SSF54862 154 270 4.19E-18 T 29-03-2018 CB4_RS07335 500ec1b4d76d6d3942aea464d67d7e02 293 Gene3D G3DSA:3.30.70.20 229 253 3.7E-10 T 29-03-2018 CB4_RS07335 500ec1b4d76d6d3942aea464d67d7e02 293 Gene3D G3DSA:3.30.70.20 184 228 1.8E-11 T 29-03-2018 CB4_RS07335 500ec1b4d76d6d3942aea464d67d7e02 293 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 251 262 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 SUPERFAMILY SSF48592 17 137 2.62E-62 T 29-03-2018 CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 SUPERFAMILY SSF48592 385 506 2.62E-62 T 29-03-2018 CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 Gene3D G3DSA:1.10.560.10 352 501 5.5E-26 T 29-03-2018 IPR027413 GroEL-like equatorial domain CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 SUPERFAMILY SSF52029 197 342 2.88E-18 T 29-03-2018 IPR027409 GroEL-like apical domain CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 Gene3D G3DSA:3.50.7.10 195 351 1.1E-17 T 29-03-2018 IPR027409 GroEL-like apical domain CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 Gene3D G3DSA:1.10.560.10 13 154 1.2E-28 T 29-03-2018 IPR027413 GroEL-like equatorial domain CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 54 70 - T 29-03-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 Pfam PF00118 TCP-1/cpn60 chaperonin family 30 507 3.9E-100 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 52 70 6.0E-28 T 29-03-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 82 101 6.0E-28 T 29-03-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 31 47 6.0E-28 T 29-03-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 355 377 6.0E-28 T 29-03-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CB4_RS06675 0ea572727eec81a3bcfd4673d8094f7b 514 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 388 400 6.0E-28 T 29-03-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CB4_RS03845 4372dc56d2611371355df165d52adedf 461 PRINTS PR00045 Sigma-54 factor signature 173 190 2.0E-30 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CB4_RS03845 4372dc56d2611371355df165d52adedf 461 PRINTS PR00045 Sigma-54 factor signature 360 372 2.0E-30 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CB4_RS03845 4372dc56d2611371355df165d52adedf 461 PRINTS PR00045 Sigma-54 factor signature 435 453 2.0E-30 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CB4_RS03845 4372dc56d2611371355df165d52adedf 461 PRINTS PR00045 Sigma-54 factor signature 376 387 2.0E-30 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CB4_RS03845 4372dc56d2611371355df165d52adedf 461 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 459 1.1E-137 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CB4_RS03845 4372dc56d2611371355df165d52adedf 461 Pfam PF04963 Sigma-54 factor, core binding domain 107 287 2.2E-53 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CB4_RS03845 4372dc56d2611371355df165d52adedf 461 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 440 447 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CB4_RS03845 4372dc56d2611371355df165d52adedf 461 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 348 367 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CB4_RS03845 4372dc56d2611371355df165d52adedf 461 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 7 51 8.8E-17 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CB4_RS03845 4372dc56d2611371355df165d52adedf 461 Gene3D G3DSA:1.10.10.10 115 308 0.093 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03845 4372dc56d2611371355df165d52adedf 461 Gene3D G3DSA:1.10.10.10 309 397 7.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03845 4372dc56d2611371355df165d52adedf 461 Pfam PF04552 Sigma-54, DNA binding domain 301 460 1.4E-64 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CB4_RS03845 4372dc56d2611371355df165d52adedf 461 PIRSF PIRSF000774 1 461 4.8E-151 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CB4_RS07545 eb882ce86defeebd78e0b630786eb2d3 355 Gene3D G3DSA:3.40.630.10 170 352 2.6E-42 T 29-03-2018 CB4_RS07545 eb882ce86defeebd78e0b630786eb2d3 355 SUPERFAMILY SSF53187 5 80 5.56E-66 T 29-03-2018 CB4_RS07545 eb882ce86defeebd78e0b630786eb2d3 355 SUPERFAMILY SSF53187 171 346 5.56E-66 T 29-03-2018 CB4_RS07545 eb882ce86defeebd78e0b630786eb2d3 355 SUPERFAMILY SSF101821 71 179 2.75E-30 T 29-03-2018 CB4_RS07545 eb882ce86defeebd78e0b630786eb2d3 355 Gene3D G3DSA:2.40.30.40 69 160 1.0E-31 T 29-03-2018 IPR023367 Peptidase M42, domain 2 CB4_RS07545 eb882ce86defeebd78e0b630786eb2d3 355 PIRSF PIRSF001123 1 355 1.9E-139 T 29-03-2018 IPR008007 Peptidase M42 CB4_RS07545 eb882ce86defeebd78e0b630786eb2d3 355 Pfam PF05343 M42 glutamyl aminopeptidase 45 336 3.3E-108 T 29-03-2018 IPR008007 Peptidase M42 CB4_RS07715 fbce14c3b899ed64f3b80ec1d6f078a3 272 SUPERFAMILY SSF55681 1 272 9.94E-68 T 29-03-2018 CB4_RS07715 fbce14c3b899ed64f3b80ec1d6f078a3 272 Gene3D G3DSA:3.30.930.10 1 272 4.3E-58 T 29-03-2018 CB4_RS07715 fbce14c3b899ed64f3b80ec1d6f078a3 272 Pfam PF03099 Biotin/lipoate A/B protein ligase family 50 183 3.2E-23 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CB4_RS04955 f8c6c4fae1297cabb66e4011164e6c0a 157 SUPERFAMILY SSF141523 28 156 3.79E-36 T 29-03-2018 CB4_RS04955 f8c6c4fae1297cabb66e4011164e6c0a 157 Gene3D G3DSA:2.40.440.10 25 157 6.2E-36 T 29-03-2018 CB4_RS04955 f8c6c4fae1297cabb66e4011164e6c0a 157 Pfam PF03734 L,D-transpeptidase catalytic domain 32 155 1.5E-27 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CB4_RS12030 332f3ae38d12d32f020920695527a8da 660 ProDom PD485437 REGULATOR TRANSCRIPTIONAL FIS-TYPE HELIX-TURN-HELIX ACTIVATOR PLASMID FAMILY PHENOL-DEGRADATIVE FIS SIGMA-54 36 141 1.0E-20 T 29-03-2018 IPR010523 Activator of aromatic catabolism CB4_RS12030 332f3ae38d12d32f020920695527a8da 660 SMART SM00989 127 189 2.8E-24 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR CB4_RS12030 332f3ae38d12d32f020920695527a8da 660 Pfam PF02830 V4R domain 128 188 1.3E-16 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR CB4_RS12030 332f3ae38d12d32f020920695527a8da 660 Pfam PF13556 PucR C-terminal helix-turn-helix domain 582 640 1.1E-14 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CB4_RS12030 332f3ae38d12d32f020920695527a8da 660 Gene3D G3DSA:3.30.450.40 213 373 7.2E-7 T 29-03-2018 IPR029016 GAF domain-like CB4_RS12030 332f3ae38d12d32f020920695527a8da 660 SUPERFAMILY SSF111126 51 186 7.32E-16 T 29-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain CB4_RS12030 332f3ae38d12d32f020920695527a8da 660 Gene3D G3DSA:3.30.1380.20 24 195 2.5E-39 T 29-03-2018 CB4_RS12030 332f3ae38d12d32f020920695527a8da 660 Pfam PF06505 Activator of aromatic catabolism 17 115 1.8E-29 T 29-03-2018 IPR010523 Activator of aromatic catabolism CB4_RS11310 cc3774ae1f1e629339bb22856a5859dd 221 Gene3D G3DSA:1.10.10.10 26 163 5.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS11310 cc3774ae1f1e629339bb22856a5859dd 221 Pfam PF13730 Helix-turn-helix domain 44 87 2.4E-7 T 29-03-2018 CB4_RS02835 77dd7bae4ab2ed4ac460a492349a87ce 454 Pfam PF02386 Cation transport protein 45 432 8.2E-61 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CB4_RS02835 77dd7bae4ab2ed4ac460a492349a87ce 454 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 38 425 4.2E-109 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 PIRSF PIRSF016578 4 380 6.9E-27 T 29-03-2018 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 Gene3D G3DSA:1.10.540.10 1 122 1.0E-39 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 4.3E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.3E-52 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 Gene3D G3DSA:2.40.110.10 123 217 2.3E-37 T 29-03-2018 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 SUPERFAMILY SSF47203 228 377 1.5E-59 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 Gene3D G3DSA:1.20.140.10 218 378 3.6E-62 T 29-03-2018 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.3E-37 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS07165 438565d0d77c00012c32e9702a8d98a4 380 SUPERFAMILY SSF56645 1 242 2.88E-85 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CB4_RS20515 f9029b16a3ed5e763c1020cf9479bd90 114 Gene3D G3DSA:1.20.5.170 71 114 0.19 T 29-03-2018 CB4_RS18670 1eaa62e587aad432336635ed593072f3 208 Pfam PF02872 5'-nucleotidase, C-terminal domain 5 167 1.5E-45 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CB4_RS18670 1eaa62e587aad432336635ed593072f3 208 PRINTS PR01607 Apyrase family signature 63 86 1.2E-10 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CB4_RS18670 1eaa62e587aad432336635ed593072f3 208 PRINTS PR01607 Apyrase family signature 141 160 1.2E-10 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CB4_RS18670 1eaa62e587aad432336635ed593072f3 208 SUPERFAMILY SSF55816 3 203 1.01E-61 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CB4_RS18670 1eaa62e587aad432336635ed593072f3 208 Gene3D G3DSA:3.90.780.10 4 203 1.8E-64 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 1.3E-69 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 Gene3D G3DSA:3.30.360.10 162 315 6.7E-68 T 29-03-2018 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 SMART SM00846 3 152 7.5E-85 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 102 3.9E-37 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 Gene3D G3DSA:3.40.50.720 1 161 3.0E-73 T 29-03-2018 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 SUPERFAMILY SSF55347 152 314 9.52E-73 T 29-03-2018 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 1.1E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 1.1E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 1.1E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 1.1E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 1.1E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 1.7E-137 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 SUPERFAMILY SSF51735 1 179 1.16E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS18340 93df406f64abd1598ddd55872bd88eea 344 PIRSF PIRSF000149 1 335 4.3E-138 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS04815 b5dd11143e794082580d76d39350382f 359 PIRSF PIRSF038991 2 356 1.4E-79 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 CB4_RS04815 b5dd11143e794082580d76d39350382f 359 Pfam PF05145 Transition state regulatory protein AbrB 33 347 4.0E-77 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 CB4_RS04815 b5dd11143e794082580d76d39350382f 359 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 14 164 1.8E-35 T 29-03-2018 IPR017516 AbrB duplication CB4_RS04815 b5dd11143e794082580d76d39350382f 359 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 192 347 3.6E-37 T 29-03-2018 IPR017516 AbrB duplication CB4_RS15935 904d8b7adba15e93bfe9c5896c7827be 399 Gene3D G3DSA:3.40.50.300 211 368 8.2E-38 T 29-03-2018 CB4_RS15935 904d8b7adba15e93bfe9c5896c7827be 399 Gene3D G3DSA:3.40.50.300 10 210 7.1E-53 T 29-03-2018 CB4_RS15935 904d8b7adba15e93bfe9c5896c7827be 399 Pfam PF00270 DEAD/DEAH box helicase 26 190 7.3E-46 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS15935 904d8b7adba15e93bfe9c5896c7827be 399 SMART SM00487 21 219 4.2E-51 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS15935 904d8b7adba15e93bfe9c5896c7827be 399 SMART SM00490 255 336 3.3E-26 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS15935 904d8b7adba15e93bfe9c5896c7827be 399 Pfam PF00271 Helicase conserved C-terminal domain 227 336 9.6E-26 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS15935 904d8b7adba15e93bfe9c5896c7827be 399 SUPERFAMILY SSF52540 71 352 7.47E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02240 e193f317e2e3c831b54e5dbdd214a531 1092 SUPERFAMILY SSF52540 844 1091 1.36E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02240 e193f317e2e3c831b54e5dbdd214a531 1092 Pfam PF00271 Helicase conserved C-terminal domain 925 1036 1.7E-21 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS02240 e193f317e2e3c831b54e5dbdd214a531 1092 Pfam PF00176 SNF2 family N-terminal domain 657 914 1.3E-52 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CB4_RS02240 e193f317e2e3c831b54e5dbdd214a531 1092 Pfam PF04434 SWIM zinc finger 60 93 8.9E-6 T 29-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CB4_RS02240 e193f317e2e3c831b54e5dbdd214a531 1092 SUPERFAMILY SSF52540 601 842 1.28E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02240 e193f317e2e3c831b54e5dbdd214a531 1092 SMART SM00490 954 1036 4.7E-24 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS02240 e193f317e2e3c831b54e5dbdd214a531 1092 SMART SM00487 637 823 7.1E-25 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS02240 e193f317e2e3c831b54e5dbdd214a531 1092 Pfam PF08455 Bacterial SNF2 helicase associated 255 634 4.6E-91 T 29-03-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial CB4_RS02240 e193f317e2e3c831b54e5dbdd214a531 1092 Gene3D G3DSA:3.40.50.300 915 1074 1.6E-42 T 29-03-2018 CB4_RS02240 e193f317e2e3c831b54e5dbdd214a531 1092 Gene3D G3DSA:3.40.50.10810 609 836 4.4E-43 T 29-03-2018 CB4_RS20080 5d5da6511d63a5a0d3d8f322c952ba4c 132 Gene3D G3DSA:3.30.70.1290 1 132 3.3E-24 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CB4_RS20080 5d5da6511d63a5a0d3d8f322c952ba4c 132 Pfam PF01797 Transposase IS200 like 10 129 1.1E-40 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CB4_RS20080 5d5da6511d63a5a0d3d8f322c952ba4c 132 SMART SM01321 10 129 5.1E-41 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CB4_RS20080 5d5da6511d63a5a0d3d8f322c952ba4c 132 SUPERFAMILY SSF143422 1 130 2.49E-44 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CB4_RS12225 abcb58c587cc5034e82a4cc99f503bda 115 Pfam PF00893 Small Multidrug Resistance protein 4 92 4.2E-21 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CB4_RS12225 abcb58c587cc5034e82a4cc99f503bda 115 SUPERFAMILY SSF103481 8 101 2.48E-15 T 29-03-2018 CB4_RS19975 0398df7e8825d2673a82d991f237eefc 119 SUPERFAMILY SSF52091 1 116 7.85E-30 T 29-03-2018 IPR002645 STAS domain CB4_RS19975 0398df7e8825d2673a82d991f237eefc 119 Pfam PF11964 SpoIIAA-like 12 116 1.4E-17 T 29-03-2018 IPR021866 SpoIIAA-like CB4_RS19975 0398df7e8825d2673a82d991f237eefc 119 Gene3D G3DSA:3.40.50.10600 1 118 1.6E-19 T 29-03-2018 CB4_RS01335 3515096898bbf5889b947db2cb2301a6 337 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 95 113 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CB4_RS01335 3515096898bbf5889b947db2cb2301a6 337 PIRSF PIRSF006621 1 329 2.7E-105 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CB4_RS01335 3515096898bbf5889b947db2cb2301a6 337 SUPERFAMILY SSF51395 10 318 3.48E-89 T 29-03-2018 CB4_RS01335 3515096898bbf5889b947db2cb2301a6 337 Pfam PF01207 Dihydrouridine synthase (Dus) 13 312 1.7E-103 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CB4_RS01335 3515096898bbf5889b947db2cb2301a6 337 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 321 1.8E-127 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CB4_RS01335 3515096898bbf5889b947db2cb2301a6 337 Gene3D G3DSA:1.10.1200.80 252 331 2.5E-17 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CB4_RS01335 3515096898bbf5889b947db2cb2301a6 337 Gene3D G3DSA:3.20.20.70 6 247 2.0E-60 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS03550 605a48990115994c4e1cec563fc1f323 266 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 259 31.518 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CB4_RS03550 605a48990115994c4e1cec563fc1f323 266 Pfam PF00696 Amino acid kinase family 5 237 1.2E-42 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS03550 605a48990115994c4e1cec563fc1f323 266 PRINTS PR00474 Glutamate 5-kinase family signature 210 230 7.3E-5 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CB4_RS03550 605a48990115994c4e1cec563fc1f323 266 PRINTS PR00474 Glutamate 5-kinase family signature 157 184 7.3E-5 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CB4_RS03550 605a48990115994c4e1cec563fc1f323 266 PRINTS PR00474 Glutamate 5-kinase family signature 32 46 7.3E-5 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CB4_RS03550 605a48990115994c4e1cec563fc1f323 266 SUPERFAMILY SSF53633 2 260 3.14E-68 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CB4_RS03550 605a48990115994c4e1cec563fc1f323 266 PIRSF PIRSF000728 1 260 6.2E-90 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CB4_RS03550 605a48990115994c4e1cec563fc1f323 266 Gene3D G3DSA:3.40.1160.10 2 265 6.6E-59 T 29-03-2018 CB4_RS03550 605a48990115994c4e1cec563fc1f323 266 TIGRFAM TIGR00761 argB: acetylglutamate kinase 5 235 1.4E-75 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CB4_RS13645 0966367c8ab869bf20dfbacd8c9c0e34 110 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 10 108 9.2E-9 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CB4_RS13645 0966367c8ab869bf20dfbacd8c9c0e34 110 SUPERFAMILY SSF55961 4 109 2.2E-19 T 29-03-2018 CB4_RS13645 0966367c8ab869bf20dfbacd8c9c0e34 110 Gene3D G3DSA:3.30.530.20 3 110 1.1E-13 T 29-03-2018 IPR023393 START-like domain CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 SUPERFAMILY SSF55681 5 245 1.22E-89 T 29-03-2018 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 SUPERFAMILY SSF55186 554 712 9.42E-51 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 Gene3D G3DSA:3.30.930.10 3 242 9.4E-98 T 29-03-2018 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 857 0.0 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 Pfam PF02272 DHHA1 domain 735 874 1.1E-30 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 SUPERFAMILY SSF101353 246 440 2.09E-67 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 878 186.274 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 1.9E-17 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 Pfam PF01411 tRNA synthetases class II (A) 8 556 4.2E-211 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 Gene3D G3DSA:2.40.30.10 442 557 0.015 T 29-03-2018 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 SMART SM00863 655 698 1.5E-19 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 2.8E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 2.8E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 2.8E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 2.8E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 2.8E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 SUPERFAMILY SSF50447 455 554 2.06E-21 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 Gene3D G3DSA:3.30.980.10 558 701 7.0E-45 T 29-03-2018 CB4_RS06100 ef96af59ad62f45ff23972a44dbfc176 878 Gene3D G3DSA:1.20.120.330 702 823 3.8E-6 T 29-03-2018 CB4_RS18745 bdd5dbc6ed52795c8ad91c1d92342eed 81 PRINTS PR00344 Bacterial sensor protein C-terminal signature 41 54 1.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18745 bdd5dbc6ed52795c8ad91c1d92342eed 81 PRINTS PR00344 Bacterial sensor protein C-terminal signature 6 16 1.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18745 bdd5dbc6ed52795c8ad91c1d92342eed 81 PRINTS PR00344 Bacterial sensor protein C-terminal signature 17 35 1.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18745 bdd5dbc6ed52795c8ad91c1d92342eed 81 SUPERFAMILY SSF55874 2 56 4.02E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18745 bdd5dbc6ed52795c8ad91c1d92342eed 81 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3 55 3.2E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18745 bdd5dbc6ed52795c8ad91c1d92342eed 81 Gene3D G3DSA:3.30.565.10 1 71 2.8E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS04750 6d3a9fc2fe0ddea87097ed803dbf6deb 274 Gene3D G3DSA:2.60.120.280 5 155 3.6E-15 T 29-03-2018 CB4_RS04750 6d3a9fc2fe0ddea87097ed803dbf6deb 274 Pfam PF12833 Helix-turn-helix domain 190 267 3.6E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CB4_RS04750 6d3a9fc2fe0ddea87097ed803dbf6deb 274 SUPERFAMILY SSF46689 170 218 6.72E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS04750 6d3a9fc2fe0ddea87097ed803dbf6deb 274 SUPERFAMILY SSF51215 10 152 4.71E-23 T 29-03-2018 CB4_RS04750 6d3a9fc2fe0ddea87097ed803dbf6deb 274 SUPERFAMILY SSF46689 220 269 2.96E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS04750 6d3a9fc2fe0ddea87097ed803dbf6deb 274 Pfam PF02311 AraC-like ligand binding domain 16 130 1.7E-18 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CB4_RS04750 6d3a9fc2fe0ddea87097ed803dbf6deb 274 SMART SM00342 184 266 8.8E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CB4_RS04750 6d3a9fc2fe0ddea87097ed803dbf6deb 274 Gene3D G3DSA:1.10.10.60 218 273 2.6E-10 T 29-03-2018 CB4_RS04750 6d3a9fc2fe0ddea87097ed803dbf6deb 274 Gene3D G3DSA:1.10.10.60 156 217 7.9E-9 T 29-03-2018 CB4_RS01700 9a08af32455357828a81cd2a4e002028 158 SUPERFAMILY SSF53927 5 154 6.36E-60 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CB4_RS01700 9a08af32455357828a81cd2a4e002028 158 Pfam PF14437 MafB19-like deaminase 5 152 4.1E-46 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CB4_RS01700 9a08af32455357828a81cd2a4e002028 158 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 11 152 48.335 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CB4_RS01700 9a08af32455357828a81cd2a4e002028 158 Gene3D G3DSA:3.40.140.10 2 158 3.9E-54 T 29-03-2018 CB4_RS01700 9a08af32455357828a81cd2a4e002028 158 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CB4_RS12995 1978ffdbd7f9b0450e56760fa33c1789 155 SUPERFAMILY SSF46785 6 141 7.97E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12995 1978ffdbd7f9b0450e56760fa33c1789 155 SMART SM00347 27 125 7.1E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS12995 1978ffdbd7f9b0450e56760fa33c1789 155 Pfam PF01047 MarR family 34 92 3.2E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS12995 1978ffdbd7f9b0450e56760fa33c1789 155 Gene3D G3DSA:1.10.10.10 3 127 8.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS05525 6d968be454c29c2601d0f72cb76126bc 192 Pfam PF02632 BioY family 31 168 1.6E-39 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CB4_RS05525 6d968be454c29c2601d0f72cb76126bc 192 PIRSF PIRSF016661 1 179 1.3E-45 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 SUPERFAMILY SSF49493 258 345 2.09E-24 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 Gene3D G3DSA:2.10.230.10 158 196 5.6E-15 T 29-03-2018 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 Gene3D G3DSA:2.60.260.20 255 367 2.2E-29 T 29-03-2018 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 PRINTS PR00625 DnaJ domain signature 61 80 2.8E-32 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 PRINTS PR00625 DnaJ domain signature 25 40 2.8E-32 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 PRINTS PR00625 DnaJ domain signature 7 25 2.8E-32 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 PRINTS PR00625 DnaJ domain signature 41 61 2.8E-32 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 350 8.7E-141 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 Pfam PF00226 DnaJ domain 5 66 2.7E-27 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 SMART SM00271 4 61 4.5E-30 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 Pfam PF01556 DnaJ C terminal domain 116 334 9.9E-46 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 SUPERFAMILY SSF57938 130 208 9.02E-18 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 Gene3D G3DSA:2.60.260.20 110 157 4.0E-4 T 29-03-2018 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 373 41.01 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 SUPERFAMILY SSF46565 1 102 1.44E-37 T 29-03-2018 IPR001623 DnaJ domain CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 Gene3D G3DSA:2.60.260.20 197 254 4.0E-17 T 29-03-2018 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 Pfam PF00684 DnaJ central domain 143 207 6.7E-14 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 SUPERFAMILY SSF49493 213 267 2.62E-22 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 SUPERFAMILY SSF49493 110 165 2.62E-22 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CB4_RS06690 27b417c263ccc2b43ff3ceb2179f6305 378 Gene3D G3DSA:1.10.287.110 1 109 1.1E-37 T 29-03-2018 IPR001623 DnaJ domain CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 Gene3D G3DSA:2.60.40.1080 802 895 2.3E-12 T 29-03-2018 CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 Gene3D G3DSA:2.60.40.1080 897 990 1.1E-14 T 29-03-2018 CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 Gene3D G3DSA:2.60.40.1080 991 1073 3.1E-17 T 29-03-2018 CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 Gene3D G3DSA:3.40.50.880 307 538 6.8E-7 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 SMART SM00635 806 888 0.0028 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 SMART SM00635 989 1067 4.4E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 SMART SM00635 906 987 4.5E-8 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 Pfam PF16480 Domain of unknown function (DUF5057) 120 408 9.9E-29 T 29-03-2018 IPR032480 Domain of unknown function DUF5057 CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 SUPERFAMILY SSF49373 987 1070 2.08E-15 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 Pfam PF02368 Bacterial Ig-like domain (group 2) 991 1059 5.7E-7 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 Pfam PF02368 Bacterial Ig-like domain (group 2) 918 988 2.2E-8 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 Pfam PF02368 Bacterial Ig-like domain (group 2) 807 886 1.1E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 SUPERFAMILY SSF49373 806 894 9.42E-5 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS05725 ec91127018acdc703a721c84d72caeb6 1322 SUPERFAMILY SSF49373 924 990 7.06E-11 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS01745 cad92bc29bdd32d072257906cc3119f5 92 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 7.4E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CB4_RS01745 cad92bc29bdd32d072257906cc3119f5 92 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 7.4E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CB4_RS01745 cad92bc29bdd32d072257906cc3119f5 92 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 7.4E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CB4_RS01745 cad92bc29bdd32d072257906cc3119f5 92 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.7E-36 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CB4_RS01745 cad92bc29bdd32d072257906cc3119f5 92 SMART SM00411 1 90 1.0E-49 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CB4_RS01745 cad92bc29bdd32d072257906cc3119f5 92 Gene3D G3DSA:4.10.520.10 1 92 1.3E-37 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CB4_RS01745 cad92bc29bdd32d072257906cc3119f5 92 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CB4_RS01745 cad92bc29bdd32d072257906cc3119f5 92 SUPERFAMILY SSF47729 1 91 5.0E-35 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CB4_RS09810 6c2958ba08800a68c49c77a01f2750ad 506 Gene3D G3DSA:3.40.50.980 1 167 1.9E-41 T 29-03-2018 CB4_RS09810 6c2958ba08800a68c49c77a01f2750ad 506 Gene3D G3DSA:2.30.38.10 321 402 1.4E-28 T 29-03-2018 CB4_RS09810 6c2958ba08800a68c49c77a01f2750ad 506 Gene3D G3DSA:3.30.300.30 404 504 8.0E-28 T 29-03-2018 CB4_RS09810 6c2958ba08800a68c49c77a01f2750ad 506 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 493 6.2E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS09810 6c2958ba08800a68c49c77a01f2750ad 506 PRINTS PR00154 AMP-binding signature 169 177 6.4E-5 T 29-03-2018 IPR020459 AMP-binding CB4_RS09810 6c2958ba08800a68c49c77a01f2750ad 506 PRINTS PR00154 AMP-binding signature 157 168 6.4E-5 T 29-03-2018 IPR020459 AMP-binding CB4_RS09810 6c2958ba08800a68c49c77a01f2750ad 506 Pfam PF00501 AMP-binding enzyme 10 409 2.5E-109 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS09810 6c2958ba08800a68c49c77a01f2750ad 506 Gene3D G3DSA:3.40.50.980 168 320 1.2E-47 T 29-03-2018 CB4_RS09810 6c2958ba08800a68c49c77a01f2750ad 506 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS09810 6c2958ba08800a68c49c77a01f2750ad 506 SUPERFAMILY SSF56801 4 501 7.85E-160 T 29-03-2018 CB4_RS08865 02043c723ce0f12320d2422da1a866ff 245 Gene3D G3DSA:2.60.40.680 53 189 2.6E-23 T 29-03-2018 CB4_RS08865 02043c723ce0f12320d2422da1a866ff 245 SUPERFAMILY SSF49384 63 183 2.2E-21 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CB4_RS18410 b25f26503b9e41737d2e5fdb0d4415fb 144 Pfam PF03061 Thioesterase superfamily 24 106 7.7E-13 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS18410 b25f26503b9e41737d2e5fdb0d4415fb 144 PIRSF PIRSF003230 1 141 2.3E-42 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CB4_RS18410 b25f26503b9e41737d2e5fdb0d4415fb 144 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 13 127 1.8E-27 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CB4_RS18410 b25f26503b9e41737d2e5fdb0d4415fb 144 Gene3D G3DSA:3.10.129.10 1 143 4.4E-35 T 29-03-2018 CB4_RS18410 b25f26503b9e41737d2e5fdb0d4415fb 144 SUPERFAMILY SSF54637 6 135 7.47E-37 T 29-03-2018 IPR029069 HotDog domain CB4_RS03020 901ec7a30b5ccd2a570575ead53c68af 138 Pfam PF12838 4Fe-4S dicluster domain 45 102 3.4E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS03020 901ec7a30b5ccd2a570575ead53c68af 138 Gene3D G3DSA:3.30.70.20 91 135 6.9E-6 T 29-03-2018 CB4_RS03020 901ec7a30b5ccd2a570575ead53c68af 138 Gene3D G3DSA:3.30.70.20 56 90 3.1E-10 T 29-03-2018 CB4_RS03020 901ec7a30b5ccd2a570575ead53c68af 138 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS03020 901ec7a30b5ccd2a570575ead53c68af 138 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 7 122 2.2E-34 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03020 901ec7a30b5ccd2a570575ead53c68af 138 Gene3D G3DSA:3.40.50.360 2 55 0.011 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS03020 901ec7a30b5ccd2a570575ead53c68af 138 SUPERFAMILY SSF54862 24 125 1.17E-22 T 29-03-2018 CB4_RS00990 4437e934fe4f65cefb16b77ced0eb771 138 SUPERFAMILY SSF47188 2 126 1.7E-29 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CB4_RS00990 4437e934fe4f65cefb16b77ced0eb771 138 Gene3D G3DSA:1.20.120.50 1 134 1.1E-30 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CB4_RS00990 4437e934fe4f65cefb16b77ced0eb771 138 Pfam PF01814 Hemerythrin HHE cation binding domain 12 126 4.0E-11 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CB4_RS00990 4437e934fe4f65cefb16b77ced0eb771 138 ProSitePatterns PS00550 Hemerythrin family signature. 56 79 - T 29-03-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 CB4_RS00990 4437e934fe4f65cefb16b77ced0eb771 138 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 4 127 2.1E-28 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 PIRSF PIRSF039101 3 508 2.8E-202 T 29-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 SUPERFAMILY SSF55681 154 493 5.77E-119 T 29-03-2018 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 Gene3D G3DSA:3.30.930.10 148 492 1.4E-103 T 29-03-2018 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 Pfam PF01336 OB-fold nucleic acid binding domain 61 138 1.5E-14 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 PRINTS PR00982 Lysyl-tRNA synthetase signature 191 201 5.4E-40 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 PRINTS PR00982 Lysyl-tRNA synthetase signature 254 271 5.4E-40 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 PRINTS PR00982 Lysyl-tRNA synthetase signature 377 393 5.4E-40 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 PRINTS PR00982 Lysyl-tRNA synthetase signature 207 223 5.4E-40 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 PRINTS PR00982 Lysyl-tRNA synthetase signature 236 249 5.4E-40 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 Pfam PF00152 tRNA synthetases class II (D, K and N) 155 492 5.3E-83 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 7 494 4.1E-217 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 SUPERFAMILY SSF50249 6 147 3.27E-43 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 Gene3D G3DSA:2.40.50.140 7 147 3.6E-41 T 29-03-2018 CB4_RS01325 774f32f6b0ae81b82bc6067cc984f972 511 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 13 495 45.3 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CB4_RS12415 a1fc0f02058b720e6c865acea043b242 313 SUPERFAMILY SSF55729 164 290 4.08E-9 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS12415 a1fc0f02058b720e6c865acea043b242 313 Gene3D G3DSA:3.40.630.30 17 160 9.6E-12 T 29-03-2018 CB4_RS12415 a1fc0f02058b720e6c865acea043b242 313 SUPERFAMILY SSF55729 39 172 2.84E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS12415 a1fc0f02058b720e6c865acea043b242 313 Pfam PF00583 Acetyltransferase (GNAT) family 42 119 6.2E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS12415 a1fc0f02058b720e6c865acea043b242 313 Gene3D G3DSA:3.40.630.30 170 300 6.9E-8 T 29-03-2018 CB4_RS10845 d1e284a23f0320f6ccd6ec0274ac3b6e 105 SUPERFAMILY SSF54909 1 95 9.49E-23 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CB4_RS10845 d1e284a23f0320f6ccd6ec0274ac3b6e 105 Gene3D G3DSA:3.30.70.100 1 102 3.2E-20 T 29-03-2018 CB4_RS10845 d1e284a23f0320f6ccd6ec0274ac3b6e 105 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.5E-13 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 349 4.7E-131 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 238 254 2.3E-31 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 255 272 2.3E-31 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 208 222 2.3E-31 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 280 291 2.3E-31 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 169 183 2.3E-31 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00097 Anthranilate synthase component II signature 324 337 3.0E-7 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00097 Anthranilate synthase component II signature 211 220 3.0E-7 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00097 Anthranilate synthase component II signature 238 249 3.0E-7 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 Gene3D G3DSA:3.50.30.20 1 131 6.2E-52 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 Pfam PF00117 Glutamine amidotransferase class-I 171 347 4.4E-43 T 29-03-2018 IPR017926 Glutamine amidotransferase CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 Gene3D G3DSA:3.40.50.880 132 354 9.3E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 SUPERFAMILY SSF52021 1 138 2.75E-50 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 SMART SM01097 1 131 1.5E-69 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 SUPERFAMILY SSF52317 163 350 2.29E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 211 220 6.3E-12 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 324 337 6.3E-12 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 238 249 6.3E-12 T 29-03-2018 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 129 6.6E-47 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03560 67e66c2e4e8fdafbbd7b43fd9ab35f0a 358 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 353 43.365 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS05855 c3ed76420656f6fcf1564e15f788a6a4 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 28.012 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05855 c3ed76420656f6fcf1564e15f788a6a4 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 5.2E-39 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05855 c3ed76420656f6fcf1564e15f788a6a4 103 SUPERFAMILY SSF141091 1 102 7.06E-39 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05855 c3ed76420656f6fcf1564e15f788a6a4 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.2E-42 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05855 c3ed76420656f6fcf1564e15f788a6a4 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS03410 6670f8c7971b6662f539706de882f647 453 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 452 1.2E-78 T 29-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 CB4_RS03410 6670f8c7971b6662f539706de882f647 453 SUPERFAMILY SSF64518 1 248 1.27E-68 T 29-03-2018 CB4_RS03410 6670f8c7971b6662f539706de882f647 453 SUPERFAMILY SSF64518 276 453 1.27E-68 T 29-03-2018 CB4_RS03410 6670f8c7971b6662f539706de882f647 453 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 140 9.6E-25 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CB4_RS03410 6670f8c7971b6662f539706de882f647 453 Pfam PF00700 Bacterial flagellin C-terminal helical region 370 452 2.0E-7 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CB4_RS03410 6670f8c7971b6662f539706de882f647 453 Gene3D G3DSA:1.20.1330.10 38 427 1.2E-37 T 29-03-2018 CB4_RS20640 34ef3f634bad7360fd37e49c33ca0e3c 339 Pfam PF14285 Domain of unknown function (DUF4367) 233 333 5.2E-7 T 29-03-2018 IPR025377 Domain of unknown function DUF4367 CB4_RS20640 34ef3f634bad7360fd37e49c33ca0e3c 339 SUPERFAMILY SSF89392 50 201 2.35E-15 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CB4_RS20640 34ef3f634bad7360fd37e49c33ca0e3c 339 Gene3D G3DSA:2.50.20.10 25 214 1.1E-23 T 29-03-2018 CB4_RS20400 9ae5597a1473006b15ac9eff045e8849 161 SUPERFAMILY SSF52255 5 159 4.45E-68 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CB4_RS20400 9ae5597a1473006b15ac9eff045e8849 161 Gene3D G3DSA:3.40.50.7700 1 161 4.5E-69 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CB4_RS20400 9ae5597a1473006b15ac9eff045e8849 161 PIRSF PIRSF001338 1 161 6.6E-69 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CB4_RS20400 9ae5597a1473006b15ac9eff045e8849 161 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 6 159 33.62 T 29-03-2018 IPR033747 Class I PurE CB4_RS20400 9ae5597a1473006b15ac9eff045e8849 161 Pfam PF00731 AIR carboxylase 6 152 7.4E-66 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CB4_RS20400 9ae5597a1473006b15ac9eff045e8849 161 SMART SM01001 4 155 2.1E-106 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CB4_RS20400 9ae5597a1473006b15ac9eff045e8849 161 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 6 159 3.8E-67 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CB4_RS15885 96106b026075b308e8a47237ffcd8d69 146 Pfam PF06935 Protein of unknown function (DUF1284) 21 126 6.1E-20 T 29-03-2018 IPR009702 Protein of unknown function DUF1284 CB4_RS06970 368c67da898a0ee3afba4c4e4a513259 329 SUPERFAMILY SSF51412 17 306 6.11E-51 T 29-03-2018 CB4_RS06970 368c67da898a0ee3afba4c4e4a513259 329 Gene3D G3DSA:3.20.20.70 9 328 2.9E-34 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS06970 368c67da898a0ee3afba4c4e4a513259 329 Pfam PF03060 Nitronate monooxygenase 75 314 2.3E-25 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 SUPERFAMILY SSF46689 369 475 4.21E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 Gene3D G3DSA:3.40.50.300 164 327 7.0E-28 T 29-03-2018 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 Gene3D G3DSA:1.10.10.60 389 476 1.9E-17 T 29-03-2018 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 Pfam PF02954 Bacterial regulatory protein, Fis family 433 473 1.6E-12 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 Pfam PF13426 PAS domain 21 120 3.1E-7 T 29-03-2018 IPR000014 PAS domain CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 SMART SM00382 177 323 3.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 SUPERFAMILY SSF52540 156 399 2.39E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 126 5.0E-10 T 29-03-2018 IPR000014 PAS domain CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 242 257 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 456 476 6.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 439 456 6.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 Gene3D G3DSA:1.10.8.60 329 388 7.2E-18 T 29-03-2018 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 Pfam PF00158 Sigma-54 interaction domain 157 322 2.3E-60 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 SUPERFAMILY SSF55785 10 104 8.2E-12 T 29-03-2018 IPR000014 PAS domain CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 Gene3D G3DSA:3.30.450.20 9 163 2.4E-14 T 29-03-2018 CB4_RS00010 fad7a463885cc0d5ed11febe004ca97d 476 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 369 378 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 Gene3D G3DSA:1.20.120.640 306 406 7.7E-21 T 29-03-2018 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 Pfam PF09190 DALR domain 352 409 4.4E-18 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 SMART SM00840 352 416 3.7E-17 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 468 4.1E-188 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 SUPERFAMILY SSF52374 3 314 2.04E-106 T 29-03-2018 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 8.4E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 8.4E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 8.4E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 8.4E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 18 313 1.6E-136 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 469 40.444 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 SUPERFAMILY SSF47323 329 468 2.35E-33 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS01205 53e937888c67300b9be08abe1a1597a7 469 Gene3D G3DSA:3.40.50.620 1 305 3.9E-96 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS08065 1edb08ff6bb721a8b2c4945bd8e34b37 175 Gene3D G3DSA:1.10.10.10 1 166 1.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08065 1edb08ff6bb721a8b2c4945bd8e34b37 175 SMART SM00347 32 132 4.1E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS08065 1edb08ff6bb721a8b2c4945bd8e34b37 175 SUPERFAMILY SSF46785 11 116 7.49E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08065 1edb08ff6bb721a8b2c4945bd8e34b37 175 Pfam PF01047 MarR family 41 98 1.8E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS04440 3b36accf15a7ed7202cc1c297f2534e6 350 Gene3D G3DSA:1.10.3470.10 8 349 5.6E-80 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS04440 3b36accf15a7ed7202cc1c297f2534e6 350 SUPERFAMILY SSF81345 8 345 2.22E-86 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CB4_RS04440 3b36accf15a7ed7202cc1c297f2534e6 350 Pfam PF01032 FecCD transport family 22 344 4.4E-99 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CB4_RS09695 e56de3cbb33d8b54c5b3cce94c051112 357 Pfam PF09992 Phosphodiester glycosidase 178 354 5.9E-46 T 29-03-2018 IPR018711 Phosphodiester glycosidase CB4_RS12260 536475020fa46e0dcc728fdd97724705 475 Gene3D G3DSA:3.40.50.300 223 474 1.9E-49 T 29-03-2018 CB4_RS12260 536475020fa46e0dcc728fdd97724705 475 SMART SM00487 21 218 1.2E-64 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS12260 536475020fa46e0dcc728fdd97724705 475 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CB4_RS12260 536475020fa46e0dcc728fdd97724705 475 Pfam PF00271 Helicase conserved C-terminal domain 227 335 1.3E-30 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS12260 536475020fa46e0dcc728fdd97724705 475 Pfam PF00270 DEAD/DEAH box helicase 27 191 1.1E-48 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS12260 536475020fa46e0dcc728fdd97724705 475 SUPERFAMILY SSF52540 71 356 1.85E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12260 536475020fa46e0dcc728fdd97724705 475 Gene3D G3DSA:3.40.50.300 1 222 3.8E-58 T 29-03-2018 CB4_RS12260 536475020fa46e0dcc728fdd97724705 475 SMART SM00490 254 335 1.5E-36 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS13345 3cbb381a96905effb537398e5ff887f6 273 Pfam PF03374 Phage antirepressor protein KilAC domain 158 257 2.3E-30 T 29-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 CB4_RS13345 3cbb381a96905effb537398e5ff887f6 273 Pfam PF02498 BRO family, N-terminal domain 21 111 1.6E-10 T 29-03-2018 IPR003497 BRO N-terminal domain CB4_RS13345 3cbb381a96905effb537398e5ff887f6 273 SMART SM01040 10 116 1.0E-10 T 29-03-2018 IPR003497 BRO N-terminal domain CB4_RS01345 67b7bf3ee630263d7cbd537c2733258d 120 SUPERFAMILY SSF55620 2 119 2.33E-39 T 29-03-2018 CB4_RS01345 67b7bf3ee630263d7cbd537c2733258d 120 Gene3D G3DSA:3.30.1130.10 1 119 3.9E-35 T 29-03-2018 CB4_RS01345 67b7bf3ee630263d7cbd537c2733258d 120 Pfam PF02152 Dihydroneopterin aldolase 6 116 1.4E-32 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CB4_RS01345 67b7bf3ee630263d7cbd537c2733258d 120 SMART SM00905 4 117 7.8E-47 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CB4_RS01345 67b7bf3ee630263d7cbd537c2733258d 120 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 117 5.2E-38 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CB4_RS01345 67b7bf3ee630263d7cbd537c2733258d 120 TIGRFAM TIGR00526 folB_dom: FolB domain 1 119 5.3E-33 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CB4_RS17715 6cb01f9ba67296aff8b074e1b7b37516 75 SUPERFAMILY SSF50037 3 73 4.81E-17 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CB4_RS17715 6cb01f9ba67296aff8b074e1b7b37516 75 Pfam PF04023 FeoA domain 2 73 4.0E-14 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CB4_RS17715 6cb01f9ba67296aff8b074e1b7b37516 75 SMART SM00899 1 74 5.7E-15 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CB4_RS17715 6cb01f9ba67296aff8b074e1b7b37516 75 Gene3D G3DSA:2.30.30.90 1 75 6.7E-16 T 29-03-2018 CB4_RS05375 b912f4570a5d5719a45df4c7750f171b 344 SUPERFAMILY SSF55681 93 342 9.52E-85 T 29-03-2018 CB4_RS05375 b912f4570a5d5719a45df4c7750f171b 344 SUPERFAMILY SSF46589 13 100 1.78E-20 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CB4_RS05375 b912f4570a5d5719a45df4c7750f171b 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 3.8E-108 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CB4_RS05375 b912f4570a5d5719a45df4c7750f171b 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 22 88 9.2E-24 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CB4_RS05375 b912f4570a5d5719a45df4c7750f171b 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 164 342 5.6E-76 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CB4_RS05375 b912f4570a5d5719a45df4c7750f171b 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 48.898 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CB4_RS05375 b912f4570a5d5719a45df4c7750f171b 344 Gene3D G3DSA:3.30.930.10 8 344 1.3E-95 T 29-03-2018 CB4_RS05550 623a789a4a69a13b4311ac1e34d44739 345 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 241 330 1.7E-16 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CB4_RS05550 623a789a4a69a13b4311ac1e34d44739 345 SUPERFAMILY SSF102114 25 332 1.83E-72 T 29-03-2018 CB4_RS05550 623a789a4a69a13b4311ac1e34d44739 345 SMART SM00876 241 331 8.9E-32 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CB4_RS05550 623a789a4a69a13b4311ac1e34d44739 345 Hamap MF_01694 Biotin synthase [bioB]. 25 332 40.705 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CB4_RS05550 623a789a4a69a13b4311ac1e34d44739 345 SMART SM00729 65 276 6.8E-39 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS05550 623a789a4a69a13b4311ac1e34d44739 345 PIRSF PIRSF001619 8 337 6.5E-124 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CB4_RS05550 623a789a4a69a13b4311ac1e34d44739 345 Gene3D G3DSA:3.20.20.70 24 334 1.3E-52 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS05550 623a789a4a69a13b4311ac1e34d44739 345 TIGRFAM TIGR00433 bioB: biotin synthase 37 330 2.0E-119 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CB4_RS05550 623a789a4a69a13b4311ac1e34d44739 345 Pfam PF04055 Radical SAM superfamily 75 229 3.5E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS12655 4997e651ca0a67524af144f6d0943e01 322 Pfam PF00753 Metallo-beta-lactamase superfamily 15 199 5.2E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS12655 4997e651ca0a67524af144f6d0943e01 322 SMART SM00849 15 199 2.1E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS12655 4997e651ca0a67524af144f6d0943e01 322 SUPERFAMILY SSF56281 15 221 7.08E-50 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS12655 4997e651ca0a67524af144f6d0943e01 322 Gene3D G3DSA:3.60.15.10 9 226 9.8E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS03850 851d048e013a702d20131c818679aed5 367 Gene3D G3DSA:1.10.10.10 27 97 1.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03850 851d048e013a702d20131c818679aed5 367 SUPERFAMILY SSF100950 102 347 2.76E-56 T 29-03-2018 CB4_RS03850 851d048e013a702d20131c818679aed5 367 Pfam PF04198 Putative sugar-binding domain 103 347 4.6E-59 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CB4_RS03850 851d048e013a702d20131c818679aed5 367 SUPERFAMILY SSF46785 29 94 1.01E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03850 851d048e013a702d20131c818679aed5 367 Gene3D G3DSA:3.40.50.1360 105 352 5.4E-32 T 29-03-2018 CB4_RS20190 0dd1f79c27881a3402028915acb769a3 294 SUPERFAMILY SSF103481 190 285 4.71E-13 T 29-03-2018 CB4_RS20190 0dd1f79c27881a3402028915acb769a3 294 Pfam PF00892 EamA-like transporter family 147 281 2.6E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS20190 0dd1f79c27881a3402028915acb769a3 294 Pfam PF00892 EamA-like transporter family 3 137 5.5E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS20190 0dd1f79c27881a3402028915acb769a3 294 SUPERFAMILY SSF103481 39 139 9.42E-16 T 29-03-2018 CB4_RS07400 65128841e92842afde69fff42a31325f 102 Gene3D G3DSA:1.10.10.10 14 102 3.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07400 65128841e92842afde69fff42a31325f 102 SUPERFAMILY SSF46785 4 102 1.26E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07400 65128841e92842afde69fff42a31325f 102 Pfam PF01638 HxlR-like helix-turn-helix 16 102 9.5E-31 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CB4_RS01330 8720a246d5b0c5a43e97fb9d2da34b18 159 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 157 7.8E-53 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CB4_RS01330 8720a246d5b0c5a43e97fb9d2da34b18 159 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 7.6E-25 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CB4_RS01330 8720a246d5b0c5a43e97fb9d2da34b18 159 Pfam PF03449 Transcription elongation factor, N-terminal 6 76 1.7E-29 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CB4_RS01330 8720a246d5b0c5a43e97fb9d2da34b18 159 SUPERFAMILY SSF54534 82 157 4.84E-20 T 29-03-2018 CB4_RS01330 8720a246d5b0c5a43e97fb9d2da34b18 159 Gene3D G3DSA:3.10.50.30 78 158 2.6E-24 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CB4_RS01330 8720a246d5b0c5a43e97fb9d2da34b18 159 PIRSF PIRSF006092 1 159 1.8E-49 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CB4_RS01330 8720a246d5b0c5a43e97fb9d2da34b18 159 SUPERFAMILY SSF46557 4 77 1.96E-25 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CB4_RS01330 8720a246d5b0c5a43e97fb9d2da34b18 159 Gene3D G3DSA:1.10.287.180 5 77 2.3E-30 T 29-03-2018 CB4_RS01330 8720a246d5b0c5a43e97fb9d2da34b18 159 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 50 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CB4_RS01330 8720a246d5b0c5a43e97fb9d2da34b18 159 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 157 29.897 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CB4_RS00970 d902678151b504b998f32bfc9d85338b 160 Gene3D G3DSA:1.10.287.500 34 155 1.2E-5 T 29-03-2018 CB4_RS00970 d902678151b504b998f32bfc9d85338b 160 SUPERFAMILY SSF58104 35 149 7.72E-6 T 29-03-2018 CB4_RS04190 f12c089f7bf9863cde164b23ccdd7977 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 9.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS04190 f12c089f7bf9863cde164b23ccdd7977 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 9.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS04190 f12c089f7bf9863cde164b23ccdd7977 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 4.5E-24 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS04190 f12c089f7bf9863cde164b23ccdd7977 240 Pfam PF07729 FCD domain 108 231 9.4E-27 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS04190 f12c089f7bf9863cde164b23ccdd7977 240 SMART SM00895 107 233 2.9E-25 T 29-03-2018 IPR011711 GntR, C-terminal CB4_RS04190 f12c089f7bf9863cde164b23ccdd7977 240 SMART SM00345 23 82 9.9E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS04190 f12c089f7bf9863cde164b23ccdd7977 240 SUPERFAMILY SSF48008 103 239 1.65E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS04190 f12c089f7bf9863cde164b23ccdd7977 240 Gene3D G3DSA:1.20.120.530 92 240 4.7E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CB4_RS04190 f12c089f7bf9863cde164b23ccdd7977 240 Gene3D G3DSA:1.10.10.10 12 90 1.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04190 f12c089f7bf9863cde164b23ccdd7977 240 SUPERFAMILY SSF46785 13 96 3.55E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 SUPERFAMILY SSF53623 100 318 1.83E-68 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 SUPERFAMILY SSF53244 320 464 3.97E-42 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 Gene3D G3DSA:3.90.190.20 322 468 2.1E-38 T 29-03-2018 CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 SUPERFAMILY SSF51984 15 102 7.06E-28 T 29-03-2018 CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 Pfam PF08245 Mur ligase middle domain 119 301 5.0E-31 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 Gene3D G3DSA:3.40.1190.10 103 321 3.4E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 16 462 1.2E-157 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 Pfam PF01225 Mur ligase family, catalytic domain 16 114 4.7E-26 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 Pfam PF02875 Mur ligase family, glutamate ligase domain 322 403 6.9E-20 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 Gene3D G3DSA:3.40.50.720 1 102 7.3E-20 T 29-03-2018 CB4_RS05720 d0b3777be1c141fcd08a18a9363a19a0 469 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 14 468 40.641 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 Pfam PF04539 Sigma-70 region 3 109 187 3.1E-7 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 Pfam PF04542 Sigma-70 region 2 29 99 4.1E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 Gene3D G3DSA:1.10.10.10 102 149 9.4E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 Gene3D G3DSA:1.10.10.10 163 255 4.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 SUPERFAMILY SSF88946 10 99 2.2E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 222 248 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 28 251 1.1E-34 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 SUPERFAMILY SSF88659 102 169 5.23E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 29 252 1.4E-74 T 29-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 PRINTS PR00046 Major sigma-70 factor signature 222 237 6.7E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 PRINTS PR00046 Major sigma-70 factor signature 80 88 6.7E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 PRINTS PR00046 Major sigma-70 factor signature 205 217 6.7E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 PRINTS PR00046 Major sigma-70 factor signature 237 248 6.7E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 PRINTS PR00046 Major sigma-70 factor signature 56 69 6.7E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 56 69 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 PIRSF PIRSF000770 13 259 1.5E-44 T 29-03-2018 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 Pfam PF04545 Sigma-70, region 4 201 249 2.0E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 SUPERFAMILY SSF88659 166 254 1.03E-21 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS09240 81dc1ea3d8bcd24cb1bf64f209b5a740 262 Gene3D G3DSA:1.10.1740.10 13 98 7.6E-19 T 29-03-2018 CB4_RS07665 6e927eb2aa5ca6cec41b0f218e201e0b 60 Pfam PF14038 YqzE-like protein 2 49 5.1E-16 T 29-03-2018 IPR025622 YqzE-like protein CB4_RS13355 2140de1043a73b604b860a93b976b4c6 184 Gene3D G3DSA:1.10.1660.10 1 100 6.2E-5 T 29-03-2018 CB4_RS13355 2140de1043a73b604b860a93b976b4c6 184 Pfam PF12728 Helix-turn-helix domain 3 51 3.2E-8 T 29-03-2018 CB4_RS13355 2140de1043a73b604b860a93b976b4c6 184 SUPERFAMILY SSF46955 2 52 2.62E-6 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS16920 2140de1043a73b604b860a93b976b4c6 184 Gene3D G3DSA:1.10.1660.10 1 100 6.2E-5 T 29-03-2018 CB4_RS16920 2140de1043a73b604b860a93b976b4c6 184 Pfam PF12728 Helix-turn-helix domain 3 51 3.2E-8 T 29-03-2018 CB4_RS16920 2140de1043a73b604b860a93b976b4c6 184 SUPERFAMILY SSF46955 2 52 2.62E-6 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS08580 83151d59bd677d3ebee391dd4e5167b3 367 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 255 330 9.8E-6 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CB4_RS08580 83151d59bd677d3ebee391dd4e5167b3 367 SMART SM00228 133 200 7.7E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS08580 83151d59bd677d3ebee391dd4e5167b3 367 SUPERFAMILY SSF50156 141 229 3.94E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS08580 83151d59bd677d3ebee391dd4e5167b3 367 Gene3D G3DSA:3.30.230.10 46 367 2.2E-37 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS08580 83151d59bd677d3ebee391dd4e5167b3 367 Pfam PF13180 PDZ domain 137 209 5.1E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS08580 83151d59bd677d3ebee391dd4e5167b3 367 SUPERFAMILY SSF54211 251 360 5.31E-20 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 Gene3D G3DSA:3.40.1550.10 135 251 7.8E-32 T 29-03-2018 IPR028976 CheC-like domain CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 Gene3D G3DSA:3.40.1550.10 38 134 1.4E-23 T 29-03-2018 IPR028976 CheC-like domain CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 SUPERFAMILY SSF101801 344 426 3.01E-25 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 SUPERFAMILY SSF103039 37 227 9.81E-50 T 29-03-2018 IPR028976 CheC-like domain CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 PRINTS PR00956 Flagellar motor switch protein FliN signature 365 381 1.6E-28 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 PRINTS PR00956 Flagellar motor switch protein FliN signature 394 409 1.6E-28 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 PRINTS PR00956 Flagellar motor switch protein FliN signature 381 394 1.6E-28 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 PRINTS PR00956 Flagellar motor switch protein FliN signature 348 364 1.6E-28 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 348 418 5.1E-25 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 345 420 3.4E-32 T 29-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 Pfam PF04509 CheC-like family 139 173 3.6E-13 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 Pfam PF04509 CheC-like family 43 77 1.5E-11 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CB4_RS09155 ebb33ac9632db7f211013c0bb0ff4a6d 428 Gene3D G3DSA:2.30.330.10 336 428 7.6E-29 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 Gene3D G3DSA:3.30.450.20 196 317 2.9E-20 T 29-03-2018 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 SMART SM00304 339 394 1.3E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 Pfam PF02743 Cache domain 40 301 2.4E-24 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 Gene3D G3DSA:3.30.450.20 42 195 6.3E-23 T 29-03-2018 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 Pfam PF00672 HAMP domain 339 384 8.6E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 Gene3D G3DSA:1.10.287.950 453 649 1.6E-50 T 29-03-2018 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 Gene3D G3DSA:1.10.287.950 650 698 0.1 T 29-03-2018 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 Gene3D G3DSA:1.10.287.950 371 452 1.0E-7 T 29-03-2018 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 SMART SM00283 423 698 4.0E-77 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 SUPERFAMILY SSF58104 369 396 6.28E-69 T 29-03-2018 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 SUPERFAMILY SSF58104 429 697 6.28E-69 T 29-03-2018 CB4_RS17280 35278c85b5a0535ab4becc7efdeadd84 699 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 470 651 1.1E-42 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS01370 6c4fdc7551694a6aafc6e793e989f7b5 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 306 1.1E-144 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CB4_RS01370 6c4fdc7551694a6aafc6e793e989f7b5 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 294 2.8E-71 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS01370 6c4fdc7551694a6aafc6e793e989f7b5 310 Gene3D G3DSA:3.40.50.1100 41 139 2.6E-39 T 29-03-2018 CB4_RS01370 6c4fdc7551694a6aafc6e793e989f7b5 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CB4_RS01370 6c4fdc7551694a6aafc6e793e989f7b5 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 306 1.7E-135 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CB4_RS01370 6c4fdc7551694a6aafc6e793e989f7b5 310 SUPERFAMILY SSF53686 1 306 1.44E-106 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS01370 6c4fdc7551694a6aafc6e793e989f7b5 310 Gene3D G3DSA:3.40.50.1100 140 309 3.9E-58 T 29-03-2018 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 342 349 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 SUPERFAMILY SSF52949 1 178 8.83E-31 T 29-03-2018 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 PRINTS PR00481 Cytosol aminopeptidase signature 366 381 7.4E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 PRINTS PR00481 Cytosol aminopeptidase signature 257 274 7.4E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 PRINTS PR00481 Cytosol aminopeptidase signature 279 300 7.4E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 PRINTS PR00481 Cytosol aminopeptidase signature 316 337 7.4E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 PRINTS PR00481 Cytosol aminopeptidase signature 338 358 7.4E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 142 2.3E-21 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 Gene3D G3DSA:3.40.630.10 166 492 1.5E-131 T 29-03-2018 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 Gene3D G3DSA:3.40.220.10 1 164 1.9E-34 T 29-03-2018 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 SUPERFAMILY SSF53187 175 493 3.45E-115 T 29-03-2018 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 181 485 3.3E-120 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CB4_RS05290 522115725cf32d07448eb34d1223a99b 499 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 494 36.483 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CB4_RS19060 9d49e9a9921fabb2cb075c2dc51c000a 286 Gene3D G3DSA:1.10.10.10 233 284 1.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19060 9d49e9a9921fabb2cb075c2dc51c000a 286 Pfam PF14540 Nucleotidyltransferase-like 1 115 3.8E-15 T 29-03-2018 IPR029348 Nucleotidyltransferase-like domain CB4_RS19060 9d49e9a9921fabb2cb075c2dc51c000a 286 Gene3D G3DSA:3.30.460.10 1 114 9.1E-18 T 29-03-2018 CB4_RS19060 9d49e9a9921fabb2cb075c2dc51c000a 286 ProDom PD128250 YGXA BH0953 1 276 3.0E-36 T 29-03-2018 CB4_RS19060 9d49e9a9921fabb2cb075c2dc51c000a 286 Gene3D G3DSA:1.20.120.330 118 231 7.3E-40 T 29-03-2018 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.3E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.3E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.3E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.3E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 4.3E-63 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 SUPERFAMILY SSF54686 1 137 4.06E-59 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.26 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 4.9E-51 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CB4_RS00920 57f798b0ce2c6adfd6e6944644160d76 144 Gene3D G3DSA:3.90.1170.10 3 139 1.4E-52 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CB4_RS08260 2ffb3d4af3fbb98e0f5d080bac29f566 301 Gene3D G3DSA:3.90.78.10 220 301 7.1E-28 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS08260 2ffb3d4af3fbb98e0f5d080bac29f566 301 SUPERFAMILY SSF56176 14 192 1.78E-42 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CB4_RS08260 2ffb3d4af3fbb98e0f5d080bac29f566 301 Gene3D G3DSA:3.30.465.10 89 219 1.4E-34 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CB4_RS08260 2ffb3d4af3fbb98e0f5d080bac29f566 301 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 301 91.795 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS08260 2ffb3d4af3fbb98e0f5d080bac29f566 301 Gene3D G3DSA:3.30.43.10 14 88 4.0E-24 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CB4_RS08260 2ffb3d4af3fbb98e0f5d080bac29f566 301 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 299 2.0E-88 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS08260 2ffb3d4af3fbb98e0f5d080bac29f566 301 SUPERFAMILY SSF56194 196 300 1.06E-35 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS08260 2ffb3d4af3fbb98e0f5d080bac29f566 301 Pfam PF01565 FAD binding domain 35 163 6.0E-21 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CB4_RS08260 2ffb3d4af3fbb98e0f5d080bac29f566 301 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 200 298 1.1E-29 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS14125 b3d2269ff7814a91317d139e88d5c4b9 301 SMART SM00448 174 296 1.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS14125 b3d2269ff7814a91317d139e88d5c4b9 301 SUPERFAMILY SSF52172 172 299 3.98E-26 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS14125 b3d2269ff7814a91317d139e88d5c4b9 301 Gene3D G3DSA:3.40.50.2300 165 300 1.3E-25 T 29-03-2018 CB4_RS14125 b3d2269ff7814a91317d139e88d5c4b9 301 SUPERFAMILY SSF50341 7 150 4.97E-35 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS14125 b3d2269ff7814a91317d139e88d5c4b9 301 Gene3D G3DSA:2.30.30.40 99 143 2.2E-12 T 29-03-2018 CB4_RS14125 b3d2269ff7814a91317d139e88d5c4b9 301 PIRSF PIRSF002867 1 301 2.1E-106 T 29-03-2018 IPR024181 Chemotaxis response regulator CheV CB4_RS14125 b3d2269ff7814a91317d139e88d5c4b9 301 Pfam PF01584 CheW-like domain 18 150 2.3E-33 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS14125 b3d2269ff7814a91317d139e88d5c4b9 301 Gene3D G3DSA:2.40.50.180 34 98 5.3E-16 T 29-03-2018 CB4_RS14125 b3d2269ff7814a91317d139e88d5c4b9 301 Pfam PF00072 Response regulator receiver domain 176 295 4.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS14125 b3d2269ff7814a91317d139e88d5c4b9 301 SMART SM00260 13 149 3.4E-30 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS10860 4e732d98b44928123bbca2a391f8a3ea 301 SUPERFAMILY SSF51735 1 297 1.36E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS10860 4e732d98b44928123bbca2a391f8a3ea 301 Pfam PF08338 Domain of unknown function (DUF1731) 251 297 4.2E-20 T 29-03-2018 IPR013549 Domain of unknown function DUF1731 CB4_RS10860 4e732d98b44928123bbca2a391f8a3ea 301 Gene3D G3DSA:3.40.50.720 1 301 3.7E-34 T 29-03-2018 CB4_RS10860 4e732d98b44928123bbca2a391f8a3ea 301 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 131 5.9E-12 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CB4_RS10860 4e732d98b44928123bbca2a391f8a3ea 301 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 2.1E-102 T 29-03-2018 IPR010099 Epimerase family protein SDR39U1 CB4_RS17250 b9fa48df726da96e7cfe4bf0fa315d2c 198 Pfam PF01479 S4 domain 91 137 6.6E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS17250 b9fa48df726da96e7cfe4bf0fa315d2c 198 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 198 35.889 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CB4_RS17250 b9fa48df726da96e7cfe4bf0fa315d2c 198 Gene3D G3DSA:3.10.290.10 96 138 8.7E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS17250 b9fa48df726da96e7cfe4bf0fa315d2c 198 Gene3D G3DSA:1.10.1050.10 1 95 1.5E-36 T 29-03-2018 CB4_RS17250 b9fa48df726da96e7cfe4bf0fa315d2c 198 SMART SM01390 3 89 1.4E-43 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CB4_RS17250 b9fa48df726da96e7cfe4bf0fa315d2c 198 SMART SM00363 90 154 8.0E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS17250 b9fa48df726da96e7cfe4bf0fa315d2c 198 SUPERFAMILY SSF55174 3 198 3.79E-67 T 29-03-2018 CB4_RS17250 b9fa48df726da96e7cfe4bf0fa315d2c 198 Gene3D G3DSA:1.10.1050.10 139 198 7.2E-16 T 29-03-2018 CB4_RS17250 b9fa48df726da96e7cfe4bf0fa315d2c 198 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 198 5.2E-81 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CB4_RS17250 b9fa48df726da96e7cfe4bf0fa315d2c 198 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 89 4.0E-29 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CB4_RS06850 619a0c22ff8a9e2d22341d53ae700bc9 649 Gene3D G3DSA:3.30.420.40 29 211 5.8E-18 T 29-03-2018 CB4_RS06850 619a0c22ff8a9e2d22341d53ae700bc9 649 Gene3D G3DSA:3.30.420.40 212 466 3.1E-19 T 29-03-2018 CB4_RS06850 619a0c22ff8a9e2d22341d53ae700bc9 649 SUPERFAMILY SSF53067 30 185 8.74E-5 T 29-03-2018 CB4_RS06850 619a0c22ff8a9e2d22341d53ae700bc9 649 SUPERFAMILY SSF53067 335 461 1.91E-10 T 29-03-2018 CB4_RS06850 619a0c22ff8a9e2d22341d53ae700bc9 649 SUPERFAMILY SSF53067 199 263 1.91E-10 T 29-03-2018 CB4_RS00190 77d185a1acff24e167a40fab0f8ee707 453 Pfam PF07664 Ferrous iron transport protein B C terminus 238 287 1.1E-14 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CB4_RS00190 77d185a1acff24e167a40fab0f8ee707 453 Pfam PF07670 Nucleoside recognition 296 421 2.2E-16 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CB4_RS00190 77d185a1acff24e167a40fab0f8ee707 453 Pfam PF07670 Nucleoside recognition 126 214 2.3E-7 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CB4_RS06250 46e3221b23b218fcd0c9bfe94d9908ac 104 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.727 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CB4_RS06250 46e3221b23b218fcd0c9bfe94d9908ac 104 SUPERFAMILY SSF117782 1 103 4.05E-36 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CB4_RS06250 46e3221b23b218fcd0c9bfe94d9908ac 104 Pfam PF01906 Putative heavy-metal-binding 1 103 4.8E-38 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CB4_RS06250 46e3221b23b218fcd0c9bfe94d9908ac 104 Gene3D G3DSA:3.30.110.70 1 103 4.4E-36 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CB4_RS15305 7c954e8c12aed4cec3ac497720cc40ab 197 Hamap MF_01124 Adapter protein MecA [mecA]. 1 196 21.824 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CB4_RS15305 7c954e8c12aed4cec3ac497720cc40ab 197 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 88 1.7E-22 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CB4_RS15305 7c954e8c12aed4cec3ac497720cc40ab 197 Pfam PF05389 Negative regulator of genetic competence (MecA) 93 192 3.6E-17 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CB4_RS15305 7c954e8c12aed4cec3ac497720cc40ab 197 PIRSF PIRSF029008 1 197 7.1E-51 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CB4_RS16520 bd9b5b5de6d6f660efc260efb608e508 149 SUPERFAMILY SSF55729 54 120 9.3E-5 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS12850 a9c519e8cb4370bec8c9fa52dd152ecf 392 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 251 333 7.8E-15 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS12850 a9c519e8cb4370bec8c9fa52dd152ecf 392 Pfam PF07282 Putative transposase DNA-binding domain 306 370 1.2E-21 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS12850 a9c519e8cb4370bec8c9fa52dd152ecf 392 Pfam PF01385 Probable transposase 165 283 4.8E-15 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS05370 071e57857538523e6c05258588ae1c45 257 SUPERFAMILY SSF48452 142 247 7.46E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS05370 071e57857538523e6c05258588ae1c45 257 Pfam PF09986 Uncharacterized protein conserved in bacteria (DUF2225) 22 237 5.3E-61 T 29-03-2018 IPR018708 Protein of unknown function DUF2225 CB4_RS05370 071e57857538523e6c05258588ae1c45 257 Gene3D G3DSA:1.25.40.10 81 254 3.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS05370 071e57857538523e6c05258588ae1c45 257 Gene3D G3DSA:2.20.28.10 23 80 3.0E-4 T 29-03-2018 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 Gene3D G3DSA:4.10.80.40 506 537 4.3E-4 T 29-03-2018 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 Gene3D G3DSA:3.50.50.60 11 256 1.9E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 Gene3D G3DSA:3.50.50.60 340 406 1.3E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 PIRSF PIRSF000171 11 539 1.1E-39 T 29-03-2018 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 SUPERFAMILY SSF46977 431 530 6.02E-28 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 19 511 8.5E-171 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 Gene3D G3DSA:1.20.58.100 412 505 9.7E-19 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 1.1E-5 T 29-03-2018 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 353 375 1.1E-5 T 29-03-2018 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 Gene3D G3DSA:3.90.700.10 257 339 1.7E-36 T 29-03-2018 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 Pfam PF02910 Fumarate reductase flavoprotein C-term 438 528 1.1E-15 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 SUPERFAMILY SSF51905 354 406 2.91E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 SUPERFAMILY SSF51905 14 262 2.91E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 Pfam PF00890 FAD binding domain 20 390 1.3E-97 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS01390 8ad6cb150fc350ff527de8b65384b952 541 SUPERFAMILY SSF56425 237 350 1.94E-43 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS12475 497cf2c0489474581b6c536a30737f47 230 SMART SM00862 149 225 1.0E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS12475 497cf2c0489474581b6c536a30737f47 230 Gene3D G3DSA:1.10.10.10 122 230 1.0E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12475 497cf2c0489474581b6c536a30737f47 230 Pfam PF00072 Response regulator receiver domain 4 113 3.0E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS12475 497cf2c0489474581b6c536a30737f47 230 Gene3D G3DSA:3.40.50.2300 1 121 1.0E-36 T 29-03-2018 CB4_RS12475 497cf2c0489474581b6c536a30737f47 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 1.4E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS12475 497cf2c0489474581b6c536a30737f47 230 SUPERFAMILY SSF52172 1 122 6.4E-41 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS12475 497cf2c0489474581b6c536a30737f47 230 SMART SM00448 2 112 3.8E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS12475 497cf2c0489474581b6c536a30737f47 230 SUPERFAMILY SSF46894 131 226 1.87E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS20185 83e4cb22c3009a8c64e48f4e97df177e 184 Pfam PF14595 Thioredoxin 10 137 4.4E-43 T 29-03-2018 CB4_RS20185 83e4cb22c3009a8c64e48f4e97df177e 184 SUPERFAMILY SSF52833 43 135 1.62E-8 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS20185 83e4cb22c3009a8c64e48f4e97df177e 184 Gene3D G3DSA:3.40.30.10 1 182 1.1E-16 T 29-03-2018 CB4_RS01500 13658064ab934975d7bf7b4ed58bd77d 126 Gene3D G3DSA:3.30.1330.40 1 126 8.1E-49 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CB4_RS01500 13658064ab934975d7bf7b4ed58bd77d 126 Pfam PF01042 Endoribonuclease L-PSP 8 123 2.6E-46 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CB4_RS01500 13658064ab934975d7bf7b4ed58bd77d 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 100 118 - T 29-03-2018 IPR019897 RidA, conserved site CB4_RS01500 13658064ab934975d7bf7b4ed58bd77d 126 SUPERFAMILY SSF55298 3 125 6.44E-47 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CB4_RS01500 13658064ab934975d7bf7b4ed58bd77d 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 122 8.0E-53 T 29-03-2018 IPR006056 RidA family CB4_RS10070 9e951d11d0972ef7b95f0bd86283d4c0 459 Pfam PF13533 Biotin-lipoyl like 66 106 6.8E-12 T 29-03-2018 CB4_RS10070 9e951d11d0972ef7b95f0bd86283d4c0 459 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 192 455 4.2E-28 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CB4_RS10070 9e951d11d0972ef7b95f0bd86283d4c0 459 Gene3D G3DSA:2.40.50.100 63 135 2.0E-12 T 29-03-2018 CB4_RS10070 9e951d11d0972ef7b95f0bd86283d4c0 459 Gene3D G3DSA:2.40.50.100 268 458 0.31 T 29-03-2018 CB4_RS10070 9e951d11d0972ef7b95f0bd86283d4c0 459 SUPERFAMILY SSF111369 64 146 1.2E-7 T 29-03-2018 CB4_RS10070 9e951d11d0972ef7b95f0bd86283d4c0 459 SUPERFAMILY SSF111369 208 362 4.84E-7 T 29-03-2018 CB4_RS10070 9e951d11d0972ef7b95f0bd86283d4c0 459 Gene3D G3DSA:1.20.1600.10 209 267 5.6E-4 T 29-03-2018 CB4_RS10070 9e951d11d0972ef7b95f0bd86283d4c0 459 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 324 348 4.3E-6 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CB4_RS10070 9e951d11d0972ef7b95f0bd86283d4c0 459 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 73 93 4.3E-6 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CB4_RS10070 9e951d11d0972ef7b95f0bd86283d4c0 459 Pfam PF13437 HlyD family secretion protein 269 384 5.5E-10 T 29-03-2018 CB4_RS04435 21eb4ff975b3e882509e8eb8676c8be5 337 Gene3D G3DSA:3.40.50.1980 175 337 6.6E-44 T 29-03-2018 CB4_RS04435 21eb4ff975b3e882509e8eb8676c8be5 337 Pfam PF01497 Periplasmic binding protein 87 311 6.1E-36 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CB4_RS04435 21eb4ff975b3e882509e8eb8676c8be5 337 SUPERFAMILY SSF53807 66 333 1.18E-65 T 29-03-2018 CB4_RS04435 21eb4ff975b3e882509e8eb8676c8be5 337 Gene3D G3DSA:3.40.50.1980 65 174 8.7E-30 T 29-03-2018 CB4_RS13190 aa6c701bb3fc2201eeb04f2bc2a98d98 328 SUPERFAMILY SSF51679 1 326 4.06E-87 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CB4_RS13190 aa6c701bb3fc2201eeb04f2bc2a98d98 328 Gene3D G3DSA:3.20.20.30 1 328 6.0E-82 T 29-03-2018 CB4_RS13190 aa6c701bb3fc2201eeb04f2bc2a98d98 328 Pfam PF00296 Luciferase-like monooxygenase 19 296 1.9E-61 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CB4_RS09650 b7f7e574ef96ef22a78508c27dad6343 895 Gene3D G3DSA:1.20.120.20 278 408 0.049 T 29-03-2018 CB4_RS09650 b7f7e574ef96ef22a78508c27dad6343 895 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 176 1.3E-43 T 29-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CB4_RS09650 b7f7e574ef96ef22a78508c27dad6343 895 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 674 874 7.2E-53 T 29-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CB4_RS09650 b7f7e574ef96ef22a78508c27dad6343 895 Pfam PF12698 ABC-2 family transporter protein 24 165 2.7E-8 T 29-03-2018 CB4_RS09650 b7f7e574ef96ef22a78508c27dad6343 895 Pfam PF01061 ABC-2 type transporter 726 843 6.4E-9 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CB4_RS09650 b7f7e574ef96ef22a78508c27dad6343 895 Gene3D G3DSA:3.40.1710.10 48 210 1.2E-27 T 29-03-2018 CB4_RS09650 b7f7e574ef96ef22a78508c27dad6343 895 Gene3D G3DSA:1.20.1170.10 409 725 5.7E-14 T 29-03-2018 CB4_RS02360 ea274f1f70d7acbdd8b42a201041f63d 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 223 7.3E-16 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CB4_RS02360 ea274f1f70d7acbdd8b42a201041f63d 318 Gene3D G3DSA:3.40.50.720 1 317 8.7E-36 T 29-03-2018 CB4_RS02360 ea274f1f70d7acbdd8b42a201041f63d 318 SUPERFAMILY SSF51735 1 311 1.32E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS13560 089ed4bc5b527e60bd316dab12c1d016 116 Pfam PF00893 Small Multidrug Resistance protein 5 93 4.5E-17 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CB4_RS13560 089ed4bc5b527e60bd316dab12c1d016 116 SUPERFAMILY SSF103481 8 106 2.22E-12 T 29-03-2018 CB4_RS09465 1644d5e31aa6c8f5057ad9dff7ea5f7a 367 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 244 316 2.3E-14 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS09465 1644d5e31aa6c8f5057ad9dff7ea5f7a 367 Gene3D G3DSA:1.20.1270.60 74 300 6.4E-4 T 29-03-2018 CB4_RS09465 1644d5e31aa6c8f5057ad9dff7ea5f7a 367 Pfam PF12323 Helix-turn-helix domain 1 48 3.4E-19 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CB4_RS09465 1644d5e31aa6c8f5057ad9dff7ea5f7a 367 Pfam PF07282 Putative transposase DNA-binding domain 289 359 1.4E-23 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS09465 1644d5e31aa6c8f5057ad9dff7ea5f7a 367 Pfam PF01385 Probable transposase 166 275 3.4E-24 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS08585 10aef0595e6f139fe8812b2341f9fdc3 405 Hamap MF_01539 UPF0348 protein . 2 404 38.199 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 CB4_RS08585 10aef0595e6f139fe8812b2341f9fdc3 405 Pfam PF05636 HIGH Nucleotidyl Transferase 1 390 2.1E-137 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 CB4_RS08585 10aef0595e6f139fe8812b2341f9fdc3 405 Gene3D G3DSA:3.40.50.620 1 245 5.2E-55 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS08585 10aef0595e6f139fe8812b2341f9fdc3 405 SUPERFAMILY SSF52374 162 239 5.93E-17 T 29-03-2018 CB4_RS08585 10aef0595e6f139fe8812b2341f9fdc3 405 SUPERFAMILY SSF52374 1 107 5.93E-17 T 29-03-2018 CB4_RS01815 7e1a733c59bf7c05fd07fdc5017ad1c5 652 Pfam PF07730 Histidine kinase 456 516 6.4E-13 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CB4_RS01815 7e1a733c59bf7c05fd07fdc5017ad1c5 652 SUPERFAMILY SSF49785 44 165 8.16E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS01815 7e1a733c59bf7c05fd07fdc5017ad1c5 652 Pfam PF07695 7TM diverse intracellular signalling 205 406 1.3E-25 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 CB4_RS01815 7e1a733c59bf7c05fd07fdc5017ad1c5 652 Gene3D G3DSA:2.60.120.260 43 199 2.7E-10 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS01815 7e1a733c59bf7c05fd07fdc5017ad1c5 652 SUPERFAMILY SSF55874 533 646 8.89E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS01815 7e1a733c59bf7c05fd07fdc5017ad1c5 652 Gene3D G3DSA:3.30.565.10 404 648 1.1E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS19965 54d4d25d13425cde782060e3e6d5ef69 47 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 2 11 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS19965 54d4d25d13425cde782060e3e6d5ef69 47 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 20 34 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS19965 54d4d25d13425cde782060e3e6d5ef69 47 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 1 41 4.0E-17 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CB4_RS15915 0933be7d6eb5763e78f5e52dd5a6c474 133 SUPERFAMILY SSF54637 10 132 2.72E-29 T 29-03-2018 IPR029069 HotDog domain CB4_RS15915 0933be7d6eb5763e78f5e52dd5a6c474 133 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 11 127 2.0E-35 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CB4_RS15915 0933be7d6eb5763e78f5e52dd5a6c474 133 Pfam PF03061 Thioesterase superfamily 41 119 7.1E-12 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS15915 0933be7d6eb5763e78f5e52dd5a6c474 133 Gene3D G3DSA:3.10.129.10 1 133 1.8E-25 T 29-03-2018 CB4_RS09310 cf20f074988d13b0843e79924fb1ae70 152 SUPERFAMILY SSF75420 4 84 1.7E-26 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CB4_RS09310 cf20f074988d13b0843e79924fb1ae70 152 Gene3D G3DSA:2.30.30.180 88 150 6.0E-16 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CB4_RS09310 cf20f074988d13b0843e79924fb1ae70 152 Gene3D G3DSA:3.30.300.70 1 81 1.2E-26 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CB4_RS09310 cf20f074988d13b0843e79924fb1ae70 152 Pfam PF02576 RimP N-terminal domain 12 84 2.2E-29 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CB4_RS09310 cf20f074988d13b0843e79924fb1ae70 152 SUPERFAMILY SSF74942 85 152 1.57E-15 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CB4_RS09310 cf20f074988d13b0843e79924fb1ae70 152 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 152 23.67 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CB4_RS09310 cf20f074988d13b0843e79924fb1ae70 152 Pfam PF17384 RimP C-terminal SH3 domain 87 152 1.1E-13 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 Pfam PF00672 HAMP domain 204 250 9.8E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 SMART SM00283 283 558 1.4E-83 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 SMART SM00304 338 394 74.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 SMART SM00304 202 254 3.1E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 SMART SM00304 499 555 110.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 329 511 3.5E-50 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 Gene3D G3DSA:1.10.287.950 228 310 1.0E-9 T 29-03-2018 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 381 408 2.0E-23 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 24 2.0E-23 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 410 439 2.0E-23 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 161 6.0E-9 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 SUPERFAMILY SSF58104 222 256 2.88E-79 T 29-03-2018 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 SUPERFAMILY SSF58104 289 558 2.88E-79 T 29-03-2018 CB4_RS16055 a9bd8fed56a720998a09715f17ec3a6e 559 Gene3D G3DSA:1.10.287.950 311 559 2.6E-55 T 29-03-2018 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 Gene3D G3DSA:1.10.287.950 434 685 1.8E-52 T 29-03-2018 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 486 637 6.5E-35 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 SMART SM00283 395 684 3.3E-50 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 Gene3D G3DSA:3.30.450.20 29 189 1.0E-15 T 29-03-2018 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 Gene3D G3DSA:3.30.450.20 190 297 6.3E-24 T 29-03-2018 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 Pfam PF02743 Cache domain 34 288 1.3E-24 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 SMART SM00304 562 615 63.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 SMART SM00304 328 380 1.3E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 SUPERFAMILY SSF58104 348 382 7.59E-63 T 29-03-2018 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 SUPERFAMILY SSF58104 415 684 7.59E-63 T 29-03-2018 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 Pfam PF00672 HAMP domain 328 376 5.6E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS19755 3773e51065d47e46fce31221579bdae1 685 Gene3D G3DSA:1.10.287.950 340 432 1.5E-6 T 29-03-2018 CB4_RS11155 f7537f783b0f62e8654b0b92f03c89b0 637 Pfam PF07581 The GLUG motif 544 567 0.0018 T 29-03-2018 IPR011493 GLUG CB4_RS11155 f7537f783b0f62e8654b0b92f03c89b0 637 Pfam PF07581 The GLUG motif 422 448 3.2E-4 T 29-03-2018 IPR011493 GLUG CB4_RS11155 f7537f783b0f62e8654b0b92f03c89b0 637 Pfam PF07581 The GLUG motif 397 419 0.0013 T 29-03-2018 IPR011493 GLUG CB4_RS11155 f7537f783b0f62e8654b0b92f03c89b0 637 Pfam PF07581 The GLUG motif 453 477 2.4E-5 T 29-03-2018 IPR011493 GLUG CB4_RS11155 f7537f783b0f62e8654b0b92f03c89b0 637 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS05910 17ddbf5976473c6a97a6499aa563428a 289 Pfam PF00800 Prephenate dehydratase 6 190 2.7E-50 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CB4_RS05910 17ddbf5976473c6a97a6499aa563428a 289 SUPERFAMILY SSF53850 4 195 2.39E-45 T 29-03-2018 CB4_RS05910 17ddbf5976473c6a97a6499aa563428a 289 Gene3D G3DSA:3.40.190.10 1 92 4.8E-26 T 29-03-2018 CB4_RS05910 17ddbf5976473c6a97a6499aa563428a 289 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 229 236 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CB4_RS05910 17ddbf5976473c6a97a6499aa563428a 289 PIRSF PIRSF001500 1 283 1.5E-61 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CB4_RS05910 17ddbf5976473c6a97a6499aa563428a 289 Pfam PF01842 ACT domain 201 253 4.7E-7 T 29-03-2018 IPR002912 ACT domain CB4_RS05910 17ddbf5976473c6a97a6499aa563428a 289 SUPERFAMILY SSF55021 183 281 1.09E-23 T 29-03-2018 CB4_RS05910 17ddbf5976473c6a97a6499aa563428a 289 Gene3D G3DSA:3.40.190.10 93 177 1.2E-21 T 29-03-2018 CB4_RS05910 17ddbf5976473c6a97a6499aa563428a 289 Gene3D G3DSA:3.30.70.260 193 288 2.3E-23 T 29-03-2018 CB4_RS16290 c7cccc2bb17f337d422e61aa789781b4 396 SUPERFAMILY SSF143856 101 217 1.57E-50 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CB4_RS16290 c7cccc2bb17f337d422e61aa789781b4 396 PIRSF PIRSF001491 3 392 4.6E-159 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CB4_RS16290 c7cccc2bb17f337d422e61aa789781b4 396 Hamap MF_00740 Phosphopentomutase [deoB]. 4 388 54.415 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CB4_RS16290 c7cccc2bb17f337d422e61aa789781b4 396 Gene3D G3DSA:3.40.720.10 211 395 1.3E-18 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CB4_RS16290 c7cccc2bb17f337d422e61aa789781b4 396 SUPERFAMILY SSF53649 218 390 4.19E-78 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CB4_RS16290 c7cccc2bb17f337d422e61aa789781b4 396 SUPERFAMILY SSF53649 4 101 4.19E-78 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CB4_RS16290 c7cccc2bb17f337d422e61aa789781b4 396 Gene3D G3DSA:3.30.70.1250 100 210 5.4E-55 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CB4_RS16290 c7cccc2bb17f337d422e61aa789781b4 396 TIGRFAM TIGR01696 deoB: phosphopentomutase 6 385 6.6E-180 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CB4_RS16290 c7cccc2bb17f337d422e61aa789781b4 396 Pfam PF01676 Metalloenzyme superfamily 5 378 8.2E-45 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CB4_RS12115 3fa284f7c80bb9dea1d33acdda50e801 367 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 355 4.0E-79 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS12115 3fa284f7c80bb9dea1d33acdda50e801 367 Pfam PF03845 Spore germination protein 7 319 2.8E-60 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS19620 9ff8f0ef4b71da4bda3648717688c9c3 845 Gene3D G3DSA:3.40.720.10 309 737 6.0E-6 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CB4_RS19620 9ff8f0ef4b71da4bda3648717688c9c3 845 TIGRFAM TIGR02687 TIGR02687: TIGR02687 family protein 11 832 1.2E-184 T 29-03-2018 IPR014060 Conserved hypothetical protein CHP02687 CB4_RS19620 9ff8f0ef4b71da4bda3648717688c9c3 845 Pfam PF08665 PglZ domain 466 637 3.3E-45 T 29-03-2018 IPR013973 PglZ domain CB4_RS04095 323e6d3794e619d5bce2260381e397d3 414 Gene3D G3DSA:1.10.10.60 334 387 6.7E-8 T 29-03-2018 CB4_RS04095 323e6d3794e619d5bce2260381e397d3 414 Pfam PF13556 PucR C-terminal helix-turn-helix domain 351 408 3.4E-20 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CB4_RS04095 323e6d3794e619d5bce2260381e397d3 414 Gene3D G3DSA:3.30.450.40 8 133 1.2E-9 T 29-03-2018 IPR029016 GAF domain-like CB4_RS17580 127f80ad991c9dad503f4dfbd816e606 264 SMART SM00382 31 231 8.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS17580 127f80ad991c9dad503f4dfbd816e606 264 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 253 1.4E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CB4_RS17580 127f80ad991c9dad503f4dfbd816e606 264 Pfam PF00005 ABC transporter 23 183 2.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS17580 127f80ad991c9dad503f4dfbd816e606 264 Gene3D G3DSA:3.40.50.300 4 263 1.1E-60 T 29-03-2018 CB4_RS17580 127f80ad991c9dad503f4dfbd816e606 264 SUPERFAMILY SSF52540 6 254 1.14E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 Pfam PF00005 ABC transporter 801 950 4.3E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 PRINTS PR00103 cAMP-dependent protein kinase signature 209 218 2.8E-8 T 29-03-2018 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 PRINTS PR00103 cAMP-dependent protein kinase signature 166 180 2.8E-8 T 29-03-2018 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 PRINTS PR00103 cAMP-dependent protein kinase signature 181 195 2.8E-8 T 29-03-2018 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 PRINTS PR00103 cAMP-dependent protein kinase signature 221 232 2.8E-8 T 29-03-2018 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 Pfam PF00027 Cyclic nucleotide-binding domain 164 248 1.2E-21 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 Pfam PF00027 Cyclic nucleotide-binding domain 33 120 3.0E-18 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 Gene3D G3DSA:1.20.1560.10 449 771 5.7E-55 T 29-03-2018 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 SUPERFAMILY SSF90123 451 771 1.24E-61 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 Gene3D G3DSA:3.90.70.10 314 448 2.1E-41 T 29-03-2018 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 Gene3D G3DSA:3.40.50.300 772 1020 4.3E-79 T 29-03-2018 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 Pfam PF00664 ABC transporter transmembrane region 474 736 2.5E-41 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 SMART SM00382 810 996 7.7E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 SUPERFAMILY SSF51206 126 264 3.54E-32 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 Gene3D G3DSA:2.60.120.10 134 269 2.0E-33 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 SUPERFAMILY SSF52540 775 1018 1.64E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 ProSitePatterns PS00211 ABC transporters family signature. 922 936 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 172 188 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 SUPERFAMILY SSF51206 8 132 5.89E-27 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 Gene3D G3DSA:2.60.120.10 4 133 4.2E-27 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 SMART SM00100 14 132 3.3E-18 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 SMART SM00100 145 264 3.7E-22 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS10695 6656f279ac768630a1e1b28f6c64c10f 1022 Pfam PF03412 Peptidase C39 family 315 440 1.7E-35 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 CB4_RS16360 e69b4bd2506a05da56d19a59861b6c41 286 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 148 257 1.4E-21 T 29-03-2018 CB4_RS16360 e69b4bd2506a05da56d19a59861b6c41 286 SUPERFAMILY SSF54593 143 275 2.15E-33 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS16360 e69b4bd2506a05da56d19a59861b6c41 286 SUPERFAMILY SSF52242 3 129 1.18E-47 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CB4_RS16360 e69b4bd2506a05da56d19a59861b6c41 286 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 145 272 8.5E-46 T 29-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 CB4_RS16360 e69b4bd2506a05da56d19a59861b6c41 286 Gene3D G3DSA:3.10.180.10 131 278 5.5E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS16360 e69b4bd2506a05da56d19a59861b6c41 286 Pfam PF02310 B12 binding domain 5 121 5.0E-23 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CB4_RS16360 e69b4bd2506a05da56d19a59861b6c41 286 Gene3D G3DSA:3.40.50.280 1 130 1.7E-38 T 29-03-2018 CB4_RS16360 e69b4bd2506a05da56d19a59861b6c41 286 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 3 130 3.5E-51 T 29-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CB4_RS17835 9965dbc4b67a6c285f798fec29111ebc 67 Pfam PF02597 ThiS family 7 67 1.4E-11 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CB4_RS17835 9965dbc4b67a6c285f798fec29111ebc 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 67 3.1E-18 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis CB4_RS17835 9965dbc4b67a6c285f798fec29111ebc 67 SUPERFAMILY SSF54285 2 66 4.74E-16 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CB4_RS17835 9965dbc4b67a6c285f798fec29111ebc 67 Gene3D G3DSA:3.10.20.30 1 67 6.1E-18 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS20710 7704ce5a1e3d8062562834357d85fdfd 377 SMART SM00086 84 126 7.2E-4 T 29-03-2018 IPR001610 PAC motif CB4_RS20710 7704ce5a1e3d8062562834357d85fdfd 377 SMART SM00331 154 374 8.3E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS20710 7704ce5a1e3d8062562834357d85fdfd 377 SUPERFAMILY SSF55785 24 123 4.01E-27 T 29-03-2018 IPR000014 PAS domain CB4_RS20710 7704ce5a1e3d8062562834357d85fdfd 377 Gene3D G3DSA:3.60.40.10 137 375 2.9E-20 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS20710 7704ce5a1e3d8062562834357d85fdfd 377 Gene3D G3DSA:3.30.450.20 15 136 9.2E-23 T 29-03-2018 CB4_RS20710 7704ce5a1e3d8062562834357d85fdfd 377 SMART SM00091 12 78 4.5E-6 T 29-03-2018 IPR000014 PAS domain CB4_RS20710 7704ce5a1e3d8062562834357d85fdfd 377 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 18 133 7.1E-18 T 29-03-2018 IPR000014 PAS domain CB4_RS20710 7704ce5a1e3d8062562834357d85fdfd 377 Pfam PF13426 PAS domain 23 125 9.2E-16 T 29-03-2018 IPR000014 PAS domain CB4_RS20710 7704ce5a1e3d8062562834357d85fdfd 377 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 181 373 1.9E-31 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 516 874 1.5E-77 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 298 2.5E-40 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 304 356 4.0E-10 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 448 459 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 Pfam PF00391 PEP-utilising enzyme, mobile domain 421 501 1.7E-22 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 Gene3D G3DSA:3.20.20.60 533 878 1.5E-91 T 29-03-2018 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 SUPERFAMILY SSF56059 4 375 1.29E-135 T 29-03-2018 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 4 876 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 SUPERFAMILY SSF51621 509 877 1.26E-105 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 Gene3D G3DSA:3.30.470.20 244 341 1.0E-20 T 29-03-2018 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 Gene3D G3DSA:1.20.80.30 118 198 2.2E-29 T 29-03-2018 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 Gene3D G3DSA:1.10.189.10 342 389 6.9E-16 T 29-03-2018 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 SUPERFAMILY SSF52009 389 510 4.45E-33 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 Gene3D G3DSA:3.30.1490.20 3 117 3.3E-32 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 Gene3D G3DSA:3.50.30.10 390 532 8.6E-38 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CB4_RS14890 a19ab296b1017cf40c94799ef79ca565 881 PIRSF PIRSF000853 2 880 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CB4_RS03465 2b03060ab01057f9f44c8c0744a5b644 125 Gene3D G3DSA:1.20.58.380 11 94 8.8E-4 T 29-03-2018 CB4_RS18785 8e3cc880be86b4d83123f18bd1c663d1 519 Gene3D G3DSA:3.40.50.1390 7 169 9.3E-27 T 29-03-2018 CB4_RS18785 8e3cc880be86b4d83123f18bd1c663d1 519 Pfam PF07508 Recombinase 182 276 1.5E-19 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CB4_RS18785 8e3cc880be86b4d83123f18bd1c663d1 519 Gene3D G3DSA:1.10.287.510 331 453 2.8E-4 T 29-03-2018 CB4_RS18785 8e3cc880be86b4d83123f18bd1c663d1 519 SUPERFAMILY SSF53041 11 159 1.44E-22 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18785 8e3cc880be86b4d83123f18bd1c663d1 519 SMART SM00857 13 159 1.6E-25 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18785 8e3cc880be86b4d83123f18bd1c663d1 519 Pfam PF00239 Resolvase, N terminal domain 14 158 1.2E-20 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS00910 47461b3c6862167e3b91adb86ab67f90 88 Pfam PF00366 Ribosomal protein S17 13 80 2.6E-33 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00910 47461b3c6862167e3b91adb86ab67f90 88 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 8 83 25.574 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00910 47461b3c6862167e3b91adb86ab67f90 88 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 8 79 2.0E-29 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00910 47461b3c6862167e3b91adb86ab67f90 88 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 8 79 8.5E-37 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00910 47461b3c6862167e3b91adb86ab67f90 88 ProSitePatterns PS00056 Ribosomal protein S17 signature. 59 71 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00910 47461b3c6862167e3b91adb86ab67f90 88 PRINTS PR00973 Ribosomal protein S17 family signature 27 50 1.3E-12 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00910 47461b3c6862167e3b91adb86ab67f90 88 PRINTS PR00973 Ribosomal protein S17 family signature 59 69 1.3E-12 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00910 47461b3c6862167e3b91adb86ab67f90 88 PRINTS PR00973 Ribosomal protein S17 family signature 69 76 1.3E-12 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00910 47461b3c6862167e3b91adb86ab67f90 88 SUPERFAMILY SSF50249 8 85 6.0E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS00910 47461b3c6862167e3b91adb86ab67f90 88 Gene3D G3DSA:2.40.50.140 8 85 4.7E-31 T 29-03-2018 CB4_RS01770 62e399b4c0e888cb3fc69f791760a26d 259 Gene3D G3DSA:3.30.950.10 122 242 1.0E-26 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01770 62e399b4c0e888cb3fc69f791760a26d 259 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 253 3.4E-112 T 29-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 CB4_RS01770 62e399b4c0e888cb3fc69f791760a26d 259 SUPERFAMILY SSF53790 2 233 6.15E-69 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01770 62e399b4c0e888cb3fc69f791760a26d 259 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 4.0E-48 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01770 62e399b4c0e888cb3fc69f791760a26d 259 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CB4_RS01770 62e399b4c0e888cb3fc69f791760a26d 259 Gene3D G3DSA:3.40.1010.10 1 121 2.9E-34 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS07100 9ec82d261e46e48a55c666445e731ca4 160 Pfam PF02130 Uncharacterized protein family UPF0054 17 154 1.2E-50 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CB4_RS07100 9ec82d261e46e48a55c666445e731ca4 160 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 125 135 - T 29-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CB4_RS07100 9ec82d261e46e48a55c666445e731ca4 160 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 155 5.3E-43 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CB4_RS07100 9ec82d261e46e48a55c666445e731ca4 160 SUPERFAMILY SSF55486 19 157 1.83E-44 T 29-03-2018 CB4_RS07100 9ec82d261e46e48a55c666445e731ca4 160 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 159 24.703 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CB4_RS07100 9ec82d261e46e48a55c666445e731ca4 160 Gene3D G3DSA:3.40.390.30 1 160 6.6E-52 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Pfam PF02810 SEC-C motif 817 835 1.1E-6 T 29-03-2018 IPR004027 SEC-C motif CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Gene3D G3DSA:1.10.3060.10 586 687 9.5E-28 T 29-03-2018 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 SMART SM00957 5 383 8.9E-291 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 PRINTS PR00906 SecA protein signature 116 126 2.3E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 PRINTS PR00906 SecA protein signature 169 189 2.3E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 PRINTS PR00906 SecA protein signature 100 114 2.3E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 PRINTS PR00906 SecA protein signature 394 407 2.3E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 PRINTS PR00906 SecA protein signature 62 86 2.3E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 PRINTS PR00906 SecA protein signature 357 374 2.3E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 PRINTS PR00906 SecA protein signature 320 342 2.3E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 SUPERFAMILY SSF81886 572 825 4.84E-76 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Pfam PF07516 SecA Wing and Scaffold domain 569 779 1.9E-62 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Gene3D G3DSA:3.10.450.50 688 836 9.5E-43 T 29-03-2018 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Gene3D G3DSA:3.40.50.300 8 270 5.9E-57 T 29-03-2018 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Gene3D G3DSA:3.40.50.300 283 397 2.1E-8 T 29-03-2018 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Pfam PF00271 Helicase conserved C-terminal domain 425 531 1.5E-4 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 497 6.6E-237 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 SUPERFAMILY SSF52540 349 396 8.18E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 SUPERFAMILY SSF52540 3 227 8.18E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Pfam PF01043 SecA preprotein cross-linking domain 231 339 1.2E-40 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Gene3D G3DSA:3.40.50.300 398 585 2.5E-57 T 29-03-2018 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Pfam PF07517 SecA DEAD-like domain 5 383 1.3E-131 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 SUPERFAMILY SSF52540 398 570 6.15E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 SUPERFAMILY SSF81767 226 349 8.37E-45 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 SMART SM00958 227 339 3.2E-64 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 782 19.933 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CB4_RS03510 f5ff97cfe892869e8f55cb3daa7d22b1 837 ProSitePatterns PS01312 SecA family signature. 481 496 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CB4_RS05500 930409068be14deb2818aee8d01d1f01 105 Gene3D G3DSA:3.40.30.10 1 105 1.1E-38 T 29-03-2018 CB4_RS05500 930409068be14deb2818aee8d01d1f01 105 Pfam PF00085 Thioredoxin 3 104 4.7E-33 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CB4_RS05500 930409068be14deb2818aee8d01d1f01 105 SUPERFAMILY SSF52833 3 105 1.22E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS05500 930409068be14deb2818aee8d01d1f01 105 PIRSF PIRSF000077 1 105 3.0E-43 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CB4_RS05500 930409068be14deb2818aee8d01d1f01 105 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 104 3.1E-40 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CB4_RS05500 930409068be14deb2818aee8d01d1f01 105 PRINTS PR00421 Thioredoxin family signature 29 38 3.9E-9 T 29-03-2018 CB4_RS05500 930409068be14deb2818aee8d01d1f01 105 PRINTS PR00421 Thioredoxin family signature 69 80 3.9E-9 T 29-03-2018 CB4_RS05500 930409068be14deb2818aee8d01d1f01 105 PRINTS PR00421 Thioredoxin family signature 21 29 3.9E-9 T 29-03-2018 CB4_RS05500 930409068be14deb2818aee8d01d1f01 105 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CB4_RS20210 1b2f312cd648e6d76850951209eab359 364 Gene3D G3DSA:3.30.70.270 180 362 1.2E-40 T 29-03-2018 CB4_RS20210 1b2f312cd648e6d76850951209eab359 364 Pfam PF00990 Diguanylate cyclase, GGDEF domain 196 356 8.2E-33 T 29-03-2018 IPR000160 GGDEF domain CB4_RS20210 1b2f312cd648e6d76850951209eab359 364 SMART SM00267 185 361 3.9E-38 T 29-03-2018 IPR000160 GGDEF domain CB4_RS20210 1b2f312cd648e6d76850951209eab359 364 SUPERFAMILY SSF55073 201 363 1.49E-35 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS20210 1b2f312cd648e6d76850951209eab359 364 Pfam PF07694 5TMR of 5TMR-LYT 38 162 4.1E-8 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CB4_RS20210 1b2f312cd648e6d76850951209eab359 364 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 193 360 1.5E-34 T 29-03-2018 IPR000160 GGDEF domain CB4_RS13835 ec2ce6a7c4baac05ec78774ed254f74f 1167 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 305 696 1.2E-6 T 29-03-2018 CB4_RS13835 ec2ce6a7c4baac05ec78774ed254f74f 1167 Pfam PF12705 PD-(D/E)XK nuclease superfamily 792 1135 4.8E-57 T 29-03-2018 CB4_RS13835 ec2ce6a7c4baac05ec78774ed254f74f 1167 SUPERFAMILY SSF52540 309 698 6.48E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13835 ec2ce6a7c4baac05ec78774ed254f74f 1167 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1166 56.522 T 29-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CB4_RS13835 ec2ce6a7c4baac05ec78774ed254f74f 1167 Gene3D G3DSA:3.40.50.300 136 272 6.2E-28 T 29-03-2018 CB4_RS13835 ec2ce6a7c4baac05ec78774ed254f74f 1167 Gene3D G3DSA:3.40.50.300 1 135 1.7E-23 T 29-03-2018 CB4_RS13835 ec2ce6a7c4baac05ec78774ed254f74f 1167 Gene3D G3DSA:3.90.320.10 696 1016 2.1E-11 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CB4_RS13835 ec2ce6a7c4baac05ec78774ed254f74f 1167 Gene3D G3DSA:3.40.50.300 279 695 2.0E-26 T 29-03-2018 CB4_RS13835 ec2ce6a7c4baac05ec78774ed254f74f 1167 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1166 0.0 T 29-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CB4_RS09470 acb09fad481a50c40067e6c8318a9a87 186 SUPERFAMILY SSF160379 1 181 1.7E-51 T 29-03-2018 CB4_RS09470 acb09fad481a50c40067e6c8318a9a87 186 Gene3D G3DSA:3.30.70.1280 2 86 1.3E-33 T 29-03-2018 CB4_RS09470 acb09fad481a50c40067e6c8318a9a87 186 PIRSF PIRSF008502 1 184 1.8E-52 T 29-03-2018 IPR012545 Protein of unknown function DUF1697 CB4_RS09470 acb09fad481a50c40067e6c8318a9a87 186 Pfam PF08002 Protein of unknown function (DUF1697) 1 143 4.0E-46 T 29-03-2018 IPR012545 Protein of unknown function DUF1697 CB4_RS09470 acb09fad481a50c40067e6c8318a9a87 186 Gene3D G3DSA:3.30.70.1260 103 181 6.2E-18 T 29-03-2018 CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 560 1.4E-101 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 Gene3D G3DSA:1.20.1170.10 19 562 0.0043 T 29-03-2018 CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 510 560 5.4E-14 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 Pfam PF00460 Flagella basal body rod protein 9 38 3.9E-7 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 SUPERFAMILY SSF64518 159 264 7.19E-19 T 29-03-2018 CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 SUPERFAMILY SSF64518 300 560 7.19E-19 T 29-03-2018 CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 PRINTS PR01005 Flagellar hook-associated protein signature 167 191 2.2E-16 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 PRINTS PR01005 Flagellar hook-associated protein signature 450 469 2.2E-16 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 2.2E-16 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 PRINTS PR01005 Flagellar hook-associated protein signature 134 154 2.2E-16 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CB4_RS03405 82d7f6fb2ce463ddbb5a6134df49eac1 567 PRINTS PR01005 Flagellar hook-associated protein signature 528 552 2.2E-16 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 SUPERFAMILY SSF51735 4 160 1.17E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 Gene3D G3DSA:3.30.70.260 347 427 1.7E-14 T 29-03-2018 CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 Gene3D G3DSA:3.40.50.720 2 159 4.0E-35 T 29-03-2018 CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 SUPERFAMILY SSF55347 139 304 8.5E-53 T 29-03-2018 CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 Pfam PF01842 ACT domain 352 408 6.9E-8 T 29-03-2018 IPR002912 ACT domain CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 SUPERFAMILY SSF55021 350 424 4.01E-11 T 29-03-2018 CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 Gene3D G3DSA:3.30.360.10 160 300 2.2E-56 T 29-03-2018 CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 PIRSF PIRSF000098 3 431 1.4E-172 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 131 7.2E-23 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CB4_RS05895 7523b7eda3461171e0583ce5da88b435 433 Pfam PF00742 Homoserine dehydrogenase 139 317 1.4E-67 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 SMART SM00267 242 413 4.4E-63 T 29-03-2018 IPR000160 GGDEF domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 Gene3D G3DSA:3.30.450.20 1 125 1.6E-21 T 29-03-2018 CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 Pfam PF08448 PAS fold 6 117 2.5E-13 T 29-03-2018 IPR013656 PAS fold-4 CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 Pfam PF08448 PAS fold 141 243 5.4E-10 T 29-03-2018 IPR013656 PAS fold-4 CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 250 409 4.0E-42 T 29-03-2018 IPR000160 GGDEF domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 SUPERFAMILY SSF55073 258 411 5.26E-48 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 Pfam PF00563 EAL domain 429 663 1.0E-71 T 29-03-2018 IPR001633 EAL domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 SUPERFAMILY SSF55785 118 240 5.76E-24 T 29-03-2018 IPR000014 PAS domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 Gene3D G3DSA:3.30.450.20 126 247 2.0E-23 T 29-03-2018 CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 SMART SM00086 201 242 0.04 T 29-03-2018 IPR001610 PAC motif CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 SMART SM00086 76 118 5.0 T 29-03-2018 IPR001610 PAC motif CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 SUPERFAMILY SSF141868 428 675 1.96E-90 T 29-03-2018 IPR001633 EAL domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 SMART SM00052 423 668 2.5E-123 T 29-03-2018 IPR001633 EAL domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 Pfam PF00990 Diguanylate cyclase, GGDEF domain 253 408 4.1E-51 T 29-03-2018 IPR000160 GGDEF domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 Gene3D G3DSA:3.30.70.270 248 420 3.5E-59 T 29-03-2018 CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 SUPERFAMILY SSF55785 4 121 8.38E-15 T 29-03-2018 IPR000014 PAS domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 Gene3D G3DSA:3.20.20.450 421 678 2.1E-102 T 29-03-2018 IPR001633 EAL domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 SMART SM00091 2 66 11.0 T 29-03-2018 IPR000014 PAS domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 SMART SM00091 130 196 1.5E-5 T 29-03-2018 IPR000014 PAS domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 2 124 3.2E-10 T 29-03-2018 IPR000014 PAS domain CB4_RS02560 dfb45d70a13078a96c61262ff2eef317 679 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 126 248 2.3E-23 T 29-03-2018 IPR000014 PAS domain CB4_RS12760 f9b910c9dfd55585871b18b6c1ca85d6 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 1.0E-42 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CB4_RS12760 f9b910c9dfd55585871b18b6c1ca85d6 184 Pfam PF13563 2'-5' RNA ligase superfamily 10 165 1.3E-20 T 29-03-2018 CB4_RS12760 f9b910c9dfd55585871b18b6c1ca85d6 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 23.062 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CB4_RS12760 f9b910c9dfd55585871b18b6c1ca85d6 184 SUPERFAMILY SSF55144 1 182 1.38E-40 T 29-03-2018 IPR009097 Cyclic phosphodiesterase CB4_RS12760 f9b910c9dfd55585871b18b6c1ca85d6 184 Gene3D G3DSA:3.90.1140.10 1 184 9.2E-39 T 29-03-2018 CB4_RS01565 761857a09eb8b56938b685b44e3658b1 235 Pfam PF05175 Methyltransferase small domain 17 109 2.1E-9 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CB4_RS01565 761857a09eb8b56938b685b44e3658b1 235 Gene3D G3DSA:3.40.50.150 1 235 1.7E-37 T 29-03-2018 CB4_RS01565 761857a09eb8b56938b685b44e3658b1 235 SUPERFAMILY SSF53335 2 185 6.19E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS20655 30bb0266efe4ae8f4b45f429f7719a9a 534 Pfam PF11741 AMIN domain 222 310 4.3E-15 T 29-03-2018 IPR021731 AMIN domain CB4_RS20655 30bb0266efe4ae8f4b45f429f7719a9a 534 SUPERFAMILY SSF55383 100 184 3.53E-24 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS20655 30bb0266efe4ae8f4b45f429f7719a9a 534 SUPERFAMILY SSF53187 359 532 8.79E-56 T 29-03-2018 CB4_RS20655 30bb0266efe4ae8f4b45f429f7719a9a 534 Gene3D G3DSA:3.30.457.10 68 109 5.6E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS20655 30bb0266efe4ae8f4b45f429f7719a9a 534 Gene3D G3DSA:3.30.457.10 172 317 3.8E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS20655 30bb0266efe4ae8f4b45f429f7719a9a 534 Gene3D G3DSA:3.30.457.10 110 171 8.7E-24 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS20655 30bb0266efe4ae8f4b45f429f7719a9a 534 SMART SM00646 420 528 6.0E-48 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CB4_RS20655 30bb0266efe4ae8f4b45f429f7719a9a 534 Gene3D G3DSA:3.40.630.40 356 534 6.1E-64 T 29-03-2018 CB4_RS20655 30bb0266efe4ae8f4b45f429f7719a9a 534 Pfam PF07833 Copper amine oxidase N-terminal domain 98 188 1.5E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS20655 30bb0266efe4ae8f4b45f429f7719a9a 534 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 361 528 5.2E-53 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CB4_RS04015 a9f4eb741aede407868d5aee5e3b52c8 249 Pfam PF01614 Bacterial transcriptional regulator 128 244 8.9E-23 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CB4_RS04015 a9f4eb741aede407868d5aee5e3b52c8 249 Gene3D G3DSA:1.10.10.10 1 77 8.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04015 a9f4eb741aede407868d5aee5e3b52c8 249 Gene3D G3DSA:3.30.450.40 78 249 1.4E-41 T 29-03-2018 IPR029016 GAF domain-like CB4_RS04015 a9f4eb741aede407868d5aee5e3b52c8 249 Pfam PF09339 IclR helix-turn-helix domain 12 61 1.8E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CB4_RS04015 a9f4eb741aede407868d5aee5e3b52c8 249 SUPERFAMILY SSF46785 10 82 4.29E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04015 a9f4eb741aede407868d5aee5e3b52c8 249 SUPERFAMILY SSF55781 67 248 3.01E-41 T 29-03-2018 IPR029016 GAF domain-like CB4_RS04015 a9f4eb741aede407868d5aee5e3b52c8 249 SMART SM00346 10 99 8.3E-24 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CB4_RS03970 225c21ba354b74e5f3aa412298803aba 682 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 6 179 5.4E-49 T 29-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CB4_RS03970 225c21ba354b74e5f3aa412298803aba 682 Gene3D G3DSA:3.30.420.40 276 570 0.0012 T 29-03-2018 CB4_RS03970 225c21ba354b74e5f3aa412298803aba 682 SUPERFAMILY SSF53067 375 480 3.06E-8 T 29-03-2018 CB4_RS03970 225c21ba354b74e5f3aa412298803aba 682 SUPERFAMILY SSF53067 262 331 3.06E-8 T 29-03-2018 CB4_RS03970 225c21ba354b74e5f3aa412298803aba 682 SUPERFAMILY SSF53067 4 76 3.06E-8 T 29-03-2018 CB4_RS03970 225c21ba354b74e5f3aa412298803aba 682 Pfam PF01968 Hydantoinase/oxoprolinase 200 486 1.6E-91 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CB4_RS03970 225c21ba354b74e5f3aa412298803aba 682 Gene3D G3DSA:3.30.420.40 1 106 9.7E-5 T 29-03-2018 CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 Pfam PF01476 LysM domain 4 47 1.1E-12 T 29-03-2018 IPR018392 LysM domain CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 Pfam PF01476 LysM domain 53 96 4.4E-13 T 29-03-2018 IPR018392 LysM domain CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 SMART SM00257 3 47 2.5E-15 T 29-03-2018 IPR018392 LysM domain CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 SMART SM00257 52 96 2.4E-15 T 29-03-2018 IPR018392 LysM domain CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 Gene3D G3DSA:3.10.350.10 2 50 1.7E-15 T 29-03-2018 CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 Gene3D G3DSA:3.10.350.10 51 99 5.7E-17 T 29-03-2018 CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 SUPERFAMILY SSF54106 51 96 5.89E-12 T 29-03-2018 IPR018392 LysM domain CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 Gene3D G3DSA:3.20.20.80 100 302 3.7E-21 T 29-03-2018 CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 SUPERFAMILY SSF51445 127 289 1.16E-22 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 SUPERFAMILY SSF54106 3 47 1.44E-11 T 29-03-2018 IPR018392 LysM domain CB4_RS10525 ad67513d427cc84dfc5c9ee7be52fca2 318 Pfam PF00704 Glycosyl hydrolases family 18 128 282 2.8E-7 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CB4_RS07875 0415ebe5be9a5db35cd9d74500cbf7f0 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CB4_RS07875 0415ebe5be9a5db35cd9d74500cbf7f0 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 127 4.1E-26 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CB4_RS07875 0415ebe5be9a5db35cd9d74500cbf7f0 353 SUPERFAMILY SSF53092 2 126 1.17E-26 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CB4_RS07875 0415ebe5be9a5db35cd9d74500cbf7f0 353 Gene3D G3DSA:3.40.350.10 1 125 2.7E-29 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CB4_RS07875 0415ebe5be9a5db35cd9d74500cbf7f0 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 305 317 5.8E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS07875 0415ebe5be9a5db35cd9d74500cbf7f0 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 5.8E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS07875 0415ebe5be9a5db35cd9d74500cbf7f0 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 185 198 5.8E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS07875 0415ebe5be9a5db35cd9d74500cbf7f0 353 SUPERFAMILY SSF55920 85 348 8.77E-85 T 29-03-2018 IPR000994 Peptidase M24 CB4_RS07875 0415ebe5be9a5db35cd9d74500cbf7f0 353 Pfam PF00557 Metallopeptidase family M24 135 337 2.0E-67 T 29-03-2018 IPR000994 Peptidase M24 CB4_RS07875 0415ebe5be9a5db35cd9d74500cbf7f0 353 Gene3D G3DSA:3.90.230.10 126 352 2.0E-81 T 29-03-2018 CB4_RS09835 f4b4a30fa9599ffe28189874355ef98a 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 47.471 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CB4_RS09835 f4b4a30fa9599ffe28189874355ef98a 252 Pfam PF03746 LamB/YcsF family 4 241 1.7E-104 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CB4_RS09835 f4b4a30fa9599ffe28189874355ef98a 252 Gene3D G3DSA:3.20.20.370 3 250 1.2E-107 T 29-03-2018 CB4_RS09835 f4b4a30fa9599ffe28189874355ef98a 252 SUPERFAMILY SSF88713 2 250 1.26E-101 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS07580 1510555c0545c2812514a5b51810a891 129 Pfam PF03780 Asp23 family, cell envelope-related function 7 111 4.7E-33 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 CB4_RS08450 c9ae36347f290462cc06e78c111953a4 278 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 62 76 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CB4_RS08450 c9ae36347f290462cc06e78c111953a4 278 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 277 38.258 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CB4_RS08450 c9ae36347f290462cc06e78c111953a4 278 SUPERFAMILY SSF54506 142 275 2.23E-48 T 29-03-2018 CB4_RS08450 c9ae36347f290462cc06e78c111953a4 278 Gene3D G3DSA:3.10.310.10 1 125 1.3E-49 T 29-03-2018 CB4_RS08450 c9ae36347f290462cc06e78c111953a4 278 Pfam PF01678 Diaminopimelate epimerase 156 268 5.5E-26 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CB4_RS08450 c9ae36347f290462cc06e78c111953a4 278 Pfam PF01678 Diaminopimelate epimerase 3 123 7.3E-34 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CB4_RS08450 c9ae36347f290462cc06e78c111953a4 278 Gene3D G3DSA:3.10.310.10 126 264 6.9E-50 T 29-03-2018 CB4_RS08450 c9ae36347f290462cc06e78c111953a4 278 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 2 274 4.0E-92 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CB4_RS08450 c9ae36347f290462cc06e78c111953a4 278 SUPERFAMILY SSF54506 1 132 1.37E-44 T 29-03-2018 CB4_RS17735 60092a74d6151f09316ddbfe9b96b916 256 SMART SM00382 31 221 8.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS17735 60092a74d6151f09316ddbfe9b96b916 256 SUPERFAMILY SSF52540 6 227 3.29E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS17735 60092a74d6151f09316ddbfe9b96b916 256 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS17735 60092a74d6151f09316ddbfe9b96b916 256 Gene3D G3DSA:3.40.50.300 4 249 2.8E-69 T 29-03-2018 CB4_RS17735 60092a74d6151f09316ddbfe9b96b916 256 Pfam PF00005 ABC transporter 23 166 1.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 Gene3D G3DSA:1.10.287.70 576 648 2.3E-17 T 29-03-2018 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 59 505 3.9E-144 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 50 75 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 9.8E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 Gene3D G3DSA:1.20.210.10 46 561 1.0E-187 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02290 867fba52f0a0929e8a5f9da02920ed1f 662 SUPERFAMILY SSF81442 47 558 4.84E-174 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS09100 5f395437c689b6fc4486c6e46698b4ff 270 TIGRFAM TIGR03825 FliH_bacil: flagellar assembly protein FliH 4 264 8.2E-49 T 29-03-2018 IPR022524 Flagellar assembly FliH, Bacilli CB4_RS09100 5f395437c689b6fc4486c6e46698b4ff 270 Pfam PF02108 Flagellar assembly protein FliH 151 256 2.3E-18 T 29-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CB4_RS06030 41fd5e5295917dd74037a0603309bcb1 421 SUPERFAMILY SSF52954 326 418 4.53E-25 T 29-03-2018 IPR004154 Anticodon-binding CB4_RS06030 41fd5e5295917dd74037a0603309bcb1 421 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 3 407 3.3E-159 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CB4_RS06030 41fd5e5295917dd74037a0603309bcb1 421 PIRSF PIRSF001549 1 419 7.9E-127 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CB4_RS06030 41fd5e5295917dd74037a0603309bcb1 421 Pfam PF13393 Histidyl-tRNA synthetase 7 310 3.3E-50 T 29-03-2018 CB4_RS06030 41fd5e5295917dd74037a0603309bcb1 421 Gene3D G3DSA:3.30.930.10 1 321 3.6E-76 T 29-03-2018 CB4_RS06030 41fd5e5295917dd74037a0603309bcb1 421 SUPERFAMILY SSF55681 1 317 5.94E-102 T 29-03-2018 CB4_RS06030 41fd5e5295917dd74037a0603309bcb1 421 Pfam PF03129 Anticodon binding domain 329 417 7.1E-13 T 29-03-2018 IPR004154 Anticodon-binding CB4_RS06030 41fd5e5295917dd74037a0603309bcb1 421 Gene3D G3DSA:3.40.50.800 324 419 4.5E-19 T 29-03-2018 IPR004154 Anticodon-binding CB4_RS06030 41fd5e5295917dd74037a0603309bcb1 421 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 417 33.249 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CB4_RS09385 9476674a1a347d7a4353ab439e5b8604 331 Gene3D G3DSA:3.40.47.10 1 164 1.7E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09385 9476674a1a347d7a4353ab439e5b8604 331 Gene3D G3DSA:3.40.47.10 165 329 1.0E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09385 9476674a1a347d7a4353ab439e5b8604 331 SUPERFAMILY SSF53901 6 329 1.85E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09385 9476674a1a347d7a4353ab439e5b8604 331 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 245 329 2.2E-26 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS09385 9476674a1a347d7a4353ab439e5b8604 331 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 188 1.9E-21 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 Pfam PF13288 DXP reductoisomerase C-terminal domain 258 374 2.0E-45 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 377 1.4E-166 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 Gene3D G3DSA:1.10.1740.10 299 379 7.6E-32 T 29-03-2018 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 SUPERFAMILY SSF55347 123 261 5.23E-60 T 29-03-2018 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 Gene3D G3DSA:3.40.50.720 1 147 9.9E-51 T 29-03-2018 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 SUPERFAMILY SSF69055 288 378 1.57E-33 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 379 47.842 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 PIRSF PIRSF006205 1 379 5.5E-164 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 129 1.1E-44 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 143 226 1.8E-41 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CB4_RS09290 1ca928e20fe6208a92e0a0be930df266 379 SUPERFAMILY SSF51735 2 147 7.88E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 Gene3D G3DSA:1.20.1250.20 2 192 1.0E-38 T 29-03-2018 CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 SUPERFAMILY SSF103473 242 414 1.44E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 SUPERFAMILY SSF103473 473 502 1.44E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 SUPERFAMILY SSF103473 3 194 1.44E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 490 1.9E-118 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 Pfam PF07690 Major Facilitator Superfamily 13 404 1.7E-56 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 71 93 6.7E-6 T 29-03-2018 CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 6.7E-6 T 29-03-2018 CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 6.7E-6 T 29-03-2018 CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 332 352 6.7E-6 T 29-03-2018 CB4_RS14875 3c8d3574861cc63a8aaeeb4a7620a139 515 Gene3D G3DSA:1.20.1250.20 252 512 2.4E-26 T 29-03-2018 CB4_RS12725 6e2b0a09b53d3407f09eaa6434b50c02 320 Gene3D G3DSA:1.10.10.60 2 32 7.1E-6 T 29-03-2018 CB4_RS12725 6e2b0a09b53d3407f09eaa6434b50c02 320 Pfam PF08279 HTH domain 8 60 8.2E-14 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CB4_RS12725 6e2b0a09b53d3407f09eaa6434b50c02 320 Pfam PF13280 WYL domain 139 308 3.9E-29 T 29-03-2018 IPR026881 WYL domain CB4_RS12725 6e2b0a09b53d3407f09eaa6434b50c02 320 SUPERFAMILY SSF46785 1 60 8.65E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12725 6e2b0a09b53d3407f09eaa6434b50c02 320 Gene3D G3DSA:1.10.10.10 33 117 4.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12765 a010438cd88f9473b4c67c38f806ad4b 312 Pfam PF01545 Cation efflux family 17 215 1.1E-46 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CB4_RS12765 a010438cd88f9473b4c67c38f806ad4b 312 Pfam PF16916 Dimerisation domain of Zinc Transporter 220 296 1.2E-17 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CB4_RS12765 a010438cd88f9473b4c67c38f806ad4b 312 Gene3D G3DSA:1.20.1510.10 12 214 7.2E-45 T 29-03-2018 CB4_RS12765 a010438cd88f9473b4c67c38f806ad4b 312 SUPERFAMILY SSF160240 218 297 7.06E-16 T 29-03-2018 CB4_RS12765 a010438cd88f9473b4c67c38f806ad4b 312 SUPERFAMILY SSF161111 9 216 1.83E-51 T 29-03-2018 CB4_RS12765 a010438cd88f9473b4c67c38f806ad4b 312 Gene3D G3DSA:3.30.70.1350 215 305 6.7E-18 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CB4_RS12765 a010438cd88f9473b4c67c38f806ad4b 312 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 14 296 1.4E-72 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CB4_RS02660 a38aa7a4d78491956e2967bbdba17ff3 289 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 288 5.8E-74 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CB4_RS02660 a38aa7a4d78491956e2967bbdba17ff3 289 Gene3D G3DSA:1.20.1510.10 11 207 6.7E-46 T 29-03-2018 CB4_RS02660 a38aa7a4d78491956e2967bbdba17ff3 289 Pfam PF16916 Dimerisation domain of Zinc Transporter 213 288 8.0E-18 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CB4_RS02660 a38aa7a4d78491956e2967bbdba17ff3 289 Pfam PF01545 Cation efflux family 16 208 2.5E-52 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CB4_RS02660 a38aa7a4d78491956e2967bbdba17ff3 289 SUPERFAMILY SSF161111 8 210 2.88E-56 T 29-03-2018 CB4_RS02660 a38aa7a4d78491956e2967bbdba17ff3 289 SUPERFAMILY SSF160240 212 288 9.02E-19 T 29-03-2018 CB4_RS02660 a38aa7a4d78491956e2967bbdba17ff3 289 Gene3D G3DSA:3.30.70.1350 208 289 1.3E-17 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CB4_RS15625 1356da4249ecc3771c97265d003cbb86 1160 Gene3D G3DSA:1.25.10.10 749 1145 7.8E-4 T 29-03-2018 IPR011989 Armadillo-like helical CB4_RS15625 1356da4249ecc3771c97265d003cbb86 1160 SUPERFAMILY SSF52540 149 344 1.33E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15625 1356da4249ecc3771c97265d003cbb86 1160 Gene3D G3DSA:3.40.50.300 144 549 1.3E-6 T 29-03-2018 CB4_RS15625 1356da4249ecc3771c97265d003cbb86 1160 Pfam PF05729 NACHT domain 173 332 1.0E-6 T 29-03-2018 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 Gene3D G3DSA:1.10.260.30 328 432 7.7E-38 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 SMART SM00963 2 87 1.4E-34 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 SUPERFAMILY SSF52540 43 355 4.71E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08660 826a01deb68630e1c6d118963784c176 449 SMART SM00382 100 248 4.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS08660 826a01deb68630e1c6d118963784c176 449 Gene3D G3DSA:3.40.50.300 99 167 7.5E-13 T 29-03-2018 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 2.6E-192 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 3.3E-23 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 9.0E-80 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 SUPERFAMILY SSF47446 328 430 3.27E-37 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 Gene3D G3DSA:1.20.120.140 196 311 1.3E-32 T 29-03-2018 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 SMART SM00962 101 297 7.0E-123 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 Pfam PF02978 Signal peptide binding domain 328 427 8.3E-33 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 449 35.156 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CB4_RS08660 826a01deb68630e1c6d118963784c176 449 Gene3D G3DSA:1.20.120.140 1 92 1.5E-30 T 29-03-2018 CB4_RS11325 5c3d2aad7cde30d4f0161ebab4b411c6 494 Gene3D G3DSA:3.40.50.300 242 357 1.6E-10 T 29-03-2018 CB4_RS11325 5c3d2aad7cde30d4f0161ebab4b411c6 494 SUPERFAMILY SSF52540 92 361 3.39E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11325 5c3d2aad7cde30d4f0161ebab4b411c6 494 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 209 385 1.0E-8 T 29-03-2018 IPR018647 Domain of unknown function DUF2075 CB4_RS11325 5c3d2aad7cde30d4f0161ebab4b411c6 494 Gene3D G3DSA:3.40.50.300 79 241 0.0014 T 29-03-2018 CB4_RS17905 b2c67271ebc02ce79c1f6770fa28f826 66 Pfam PF00313 'Cold-shock' DNA-binding domain 2 65 5.7E-32 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS17905 b2c67271ebc02ce79c1f6770fa28f826 66 Gene3D G3DSA:2.40.50.140 1 66 1.4E-27 T 29-03-2018 CB4_RS17905 b2c67271ebc02ce79c1f6770fa28f826 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CB4_RS17905 b2c67271ebc02ce79c1f6770fa28f826 66 SUPERFAMILY SSF50249 2 65 1.32E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS17905 b2c67271ebc02ce79c1f6770fa28f826 66 PIRSF PIRSF002599 1 66 7.6E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CB4_RS17905 b2c67271ebc02ce79c1f6770fa28f826 66 SMART SM00357 3 66 7.1E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CB4_RS17905 b2c67271ebc02ce79c1f6770fa28f826 66 PRINTS PR00050 Cold shock protein signature 4 19 4.6E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS17905 b2c67271ebc02ce79c1f6770fa28f826 66 PRINTS PR00050 Cold shock protein signature 39 57 4.6E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS17905 b2c67271ebc02ce79c1f6770fa28f826 66 PRINTS PR00050 Cold shock protein signature 24 33 4.6E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 SMART SM00358 159 226 6.9E-21 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 Gene3D G3DSA:3.30.160.20 158 230 7.3E-22 T 29-03-2018 CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 SUPERFAMILY SSF69065 3 160 6.98E-51 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 ProSitePatterns PS00517 Ribonuclease III family signature. 42 50 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 Gene3D G3DSA:1.10.1520.10 2 151 4.1E-45 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 Pfam PF00035 Double-stranded RNA binding motif 159 225 2.1E-17 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 6 225 4.5E-81 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 SMART SM00535 18 153 2.8E-56 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 Pfam PF14622 Ribonuclease-III-like 16 146 2.9E-36 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 Hamap MF_00104 Ribonuclease 3 [rnc]. 6 222 31.769 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CB4_RS08635 8d7623a5c5a15d5dd7044f1b566bfda6 231 SUPERFAMILY SSF54768 115 225 1.89E-24 T 29-03-2018 CB4_RS00800 fc637f2f2f3b0c5c5c6aa37642dfa4f7 265 Pfam PF02361 Cobalt transport protein 14 236 7.6E-50 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CB4_RS00800 fc637f2f2f3b0c5c5c6aa37642dfa4f7 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 34.493 T 29-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 CB4_RS07525 4d21c96285952bc9ba07db92553b5ba5 510 SUPERFAMILY SSF117457 320 490 1.7E-52 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CB4_RS07525 4d21c96285952bc9ba07db92553b5ba5 510 PIRSF PIRSF001394 1 509 2.8E-187 T 29-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CB4_RS07525 4d21c96285952bc9ba07db92553b5ba5 510 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 5 281 8.9E-64 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CB4_RS07525 4d21c96285952bc9ba07db92553b5ba5 510 Pfam PF05683 Fumarase C-terminus 308 492 5.9E-61 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CB4_RS07525 4d21c96285952bc9ba07db92553b5ba5 510 Pfam PF05681 Fumarate hydratase (Fumerase) 6 280 4.1E-73 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CB4_RS07525 4d21c96285952bc9ba07db92553b5ba5 510 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 329 490 5.7E-50 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CB4_RS07525 4d21c96285952bc9ba07db92553b5ba5 510 Gene3D G3DSA:3.20.130.10 318 491 8.8E-64 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CB4_RS06150 d93fdf63df4389af30badb4990ec7e2c 247 SUPERFAMILY SSF54909 1 246 2.12E-88 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CB4_RS06150 d93fdf63df4389af30badb4990ec7e2c 247 Gene3D G3DSA:3.30.70.1030 4 135 9.2E-39 T 29-03-2018 CB4_RS06150 d93fdf63df4389af30badb4990ec7e2c 247 Pfam PF06778 Chlorite dismutase 33 236 3.0E-75 T 29-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CB4_RS06150 d93fdf63df4389af30badb4990ec7e2c 247 Gene3D G3DSA:3.30.70.1100 138 243 7.9E-31 T 29-03-2018 CB4_RS16310 3f41fabd5ba5c0cbe30908b78997497d 512 SMART SM01276 125 433 6.5E-116 T 29-03-2018 IPR031161 Peptidase family M60 domain CB4_RS16310 3f41fabd5ba5c0cbe30908b78997497d 512 Pfam PF17291 N-terminal domain of M60-like peptidases 108 213 7.1E-20 T 29-03-2018 IPR035423 M60-like domain, N-terminal CB4_RS16310 3f41fabd5ba5c0cbe30908b78997497d 512 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 214 482 1.4E-80 T 29-03-2018 IPR031161 Peptidase family M60 domain CB4_RS17005 6325d951e5a11f9ba6147f67d7d3313a 196 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 16 194 2.3E-68 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CB4_RS17005 6325d951e5a11f9ba6147f67d7d3313a 196 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 73 89 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CB4_RS17005 6325d951e5a11f9ba6147f67d7d3313a 196 Gene3D G3DSA:3.30.1130.10 63 196 1.6E-52 T 29-03-2018 CB4_RS17005 6325d951e5a11f9ba6147f67d7d3313a 196 Pfam PF01227 GTP cyclohydrolase I 16 193 6.4E-72 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CB4_RS17005 6325d951e5a11f9ba6147f67d7d3313a 196 Gene3D G3DSA:1.10.286.10 14 62 6.4E-21 T 29-03-2018 CB4_RS17005 6325d951e5a11f9ba6147f67d7d3313a 196 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 12 194 38.904 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CB4_RS17005 6325d951e5a11f9ba6147f67d7d3313a 196 SUPERFAMILY SSF55620 10 194 1.11E-73 T 29-03-2018 CB4_RS17005 6325d951e5a11f9ba6147f67d7d3313a 196 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 121 131 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CB4_RS12075 8bf975ae7ca63a1bb4d4a1fdcfe69708 90 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CB4_RS12075 8bf975ae7ca63a1bb4d4a1fdcfe69708 90 SUPERFAMILY SSF54292 4 90 2.36E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CB4_RS12075 8bf975ae7ca63a1bb4d4a1fdcfe69708 90 Gene3D G3DSA:3.10.20.30 2 90 3.7E-21 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS12075 8bf975ae7ca63a1bb4d4a1fdcfe69708 90 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 82 1.9E-16 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 1.7E-25 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 1.7E-25 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 193 203 1.7E-25 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 1.7E-25 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 1 325 5.2E-110 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 326 40.98 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 20 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 Gene3D G3DSA:3.40.50.620 1 199 3.2E-71 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 Pfam PF00579 tRNA synthetases class I (W and Y) 4 281 1.2E-76 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 Gene3D G3DSA:1.10.240.10 200 308 2.9E-32 T 29-03-2018 CB4_RS16575 b451742b7ca56a9d8cdac96539c053fc 328 SUPERFAMILY SSF52374 5 325 3.87E-97 T 29-03-2018 CB4_RS11170 25f79b90df9ad1fe4c1c96751c292e14 378 SUPERFAMILY SSF53383 4 377 3.16E-103 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS11170 25f79b90df9ad1fe4c1c96751c292e14 378 PIRSF PIRSF000390 1 378 9.4E-109 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CB4_RS11170 25f79b90df9ad1fe4c1c96751c292e14 378 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 12 375 2.0E-100 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CB4_RS11170 25f79b90df9ad1fe4c1c96751c292e14 378 Gene3D G3DSA:3.90.1150.10 244 378 4.3E-32 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS11170 25f79b90df9ad1fe4c1c96751c292e14 378 Gene3D G3DSA:3.40.640.10 4 243 5.3E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS16825 826b5894cf332edb00a0d112d2ea2733 133 SUPERFAMILY SSF52540 8 131 7.21E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS16825 826b5894cf332edb00a0d112d2ea2733 133 Pfam PF00158 Sigma-54 interaction domain 7 131 4.4E-51 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS16825 826b5894cf332edb00a0d112d2ea2733 133 Gene3D G3DSA:3.40.50.300 8 133 1.6E-23 T 29-03-2018 CB4_RS08005 2ab51bf3cb4a186dd27f1430ab5f418b 575 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 564 2.2E-186 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CB4_RS08005 2ab51bf3cb4a186dd27f1430ab5f418b 575 SUPERFAMILY SSF52540 1 202 6.69E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08005 2ab51bf3cb4a186dd27f1430ab5f418b 575 SUPERFAMILY SSF52540 288 323 6.69E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08005 2ab51bf3cb4a186dd27f1430ab5f418b 575 SUPERFAMILY SSF52540 352 520 6.69E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08005 2ab51bf3cb4a186dd27f1430ab5f418b 575 PIRSF PIRSF003128 1 569 9.7E-185 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CB4_RS08005 2ab51bf3cb4a186dd27f1430ab5f418b 575 Gene3D G3DSA:3.40.50.300 1 182 4.4E-28 T 29-03-2018 CB4_RS08005 2ab51bf3cb4a186dd27f1430ab5f418b 575 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 523 1.5E-15 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CB4_RS08005 2ab51bf3cb4a186dd27f1430ab5f418b 575 Gene3D G3DSA:3.40.50.300 233 538 6.1E-21 T 29-03-2018 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 295 8.0E-18 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 SUPERFAMILY SSF47789 247 313 4.58E-25 T 29-03-2018 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 SMART SM00662 20 227 4.5E-101 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 313 1.1E-125 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 SUPERFAMILY SSF55257 172 224 7.85E-33 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 SUPERFAMILY SSF55257 3 50 7.85E-33 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 Gene3D G3DSA:1.10.150.20 243 314 2.8E-27 T 29-03-2018 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 56 152 4.4E-24 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 SUPERFAMILY SSF56553 50 171 3.01E-43 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 9.3E-26 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 1.3E-29 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.914 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 Gene3D G3DSA:3.30.1360.10 1 91 4.8E-22 T 29-03-2018 CB4_RS00820 bcddec7f5d381f9834f97ea0fd37a21e 314 Gene3D G3DSA:3.30.1360.10 108 224 2.3E-28 T 29-03-2018 CB4_RS05590 f0e7b97a6c5c362d8ce49686850e11e0 206 Pfam PF01725 Ham1 family 12 198 8.2E-57 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CB4_RS05590 f0e7b97a6c5c362d8ce49686850e11e0 206 SUPERFAMILY SSF52972 9 202 4.45E-66 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CB4_RS05590 f0e7b97a6c5c362d8ce49686850e11e0 206 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 10 203 47.74 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CB4_RS05590 f0e7b97a6c5c362d8ce49686850e11e0 206 Gene3D G3DSA:3.90.950.10 2 206 2.1E-77 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CB4_RS05590 f0e7b97a6c5c362d8ce49686850e11e0 206 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 12 200 7.4E-55 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CB4_RS20300 da1c2515f387f9fdfb1fe34ab05bfe1b 426 Gene3D G3DSA:1.20.1250.20 221 425 4.2E-21 T 29-03-2018 CB4_RS20300 da1c2515f387f9fdfb1fe34ab05bfe1b 426 Gene3D G3DSA:1.20.1250.20 22 209 3.1E-25 T 29-03-2018 CB4_RS20300 da1c2515f387f9fdfb1fe34ab05bfe1b 426 SUPERFAMILY SSF103473 22 420 7.06E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS20300 da1c2515f387f9fdfb1fe34ab05bfe1b 426 Pfam PF07690 Major Facilitator Superfamily 36 300 2.7E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS07925 91c873f7f5f1e42afe1586c441c767b4 192 Pfam PF12685 SpoIIIAH-like protein 6 188 3.5E-31 T 29-03-2018 IPR024232 Stage III sporulation protein AH-like CB4_RS00385 fa3320663afe3d31a1ec2b37c6b627e0 115 Pfam PF06108 Protein of unknown function (DUF952) 8 97 4.8E-20 T 29-03-2018 IPR009297 Protein of unknown function DUF952 CB4_RS00385 fa3320663afe3d31a1ec2b37c6b627e0 115 SUPERFAMILY SSF56399 3 107 4.6E-19 T 29-03-2018 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 569 771 9.7E-100 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 TIGRFAM TIGR00763 lon: endopeptidase La 11 770 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 Hamap MF_01973 Lon protease [lon]. 10 771 71.532 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 Gene3D G3DSA:2.30.130.40 2 117 4.2E-30 T 29-03-2018 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 SUPERFAMILY SSF88697 9 200 5.47E-46 T 29-03-2018 IPR015947 PUA-like domain CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 SUPERFAMILY SSF52540 309 585 8.6E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 SMART SM00464 9 201 6.3E-71 T 29-03-2018 IPR003111 Lon, substrate-binding domain CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 Gene3D G3DSA:1.10.4060.10 120 210 7.9E-28 T 29-03-2018 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 SUPERFAMILY SSF54211 594 769 4.17E-58 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 351 487 5.9E-22 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 SMART SM00382 347 492 1.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 Gene3D G3DSA:3.40.50.300 312 490 4.3E-33 T 29-03-2018 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 355 374 1.2E-55 T 29-03-2018 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 725 743 1.2E-55 T 29-03-2018 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 672 691 1.2E-55 T 29-03-2018 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 702 721 1.2E-55 T 29-03-2018 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 594 610 1.2E-55 T 29-03-2018 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 Gene3D G3DSA:1.10.8.60 491 583 1.8E-29 T 29-03-2018 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 PIRSF PIRSF001174 1 774 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 Gene3D G3DSA:3.30.230.10 585 771 6.4E-69 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 675 683 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CB4_RS05630 1d4fcc252950c3b11531f163bca719f2 777 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 10 200 2.0E-41 T 29-03-2018 IPR003111 Lon, substrate-binding domain CB4_RS02960 93f125acf2fbbcd7b0e31f8000ed59ad 148 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 126 10.871 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CB4_RS02960 93f125acf2fbbcd7b0e31f8000ed59ad 148 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 2 144 1.2E-33 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CB4_RS02960 93f125acf2fbbcd7b0e31f8000ed59ad 148 Pfam PF00430 ATP synthase B/B' CF(0) 1 125 1.4E-29 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CB4_RS02960 93f125acf2fbbcd7b0e31f8000ed59ad 148 Gene3D G3DSA:1.20.5.620 50 110 2.9E-7 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CB4_RS02960 93f125acf2fbbcd7b0e31f8000ed59ad 148 SUPERFAMILY SSF81573 51 109 5.89E-7 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CB4_RS04795 0cbb11ba1173fd9b5f9150316ff18f9c 354 SMART SM00086 87 129 8.4E-5 T 29-03-2018 IPR001610 PAC motif CB4_RS04795 0cbb11ba1173fd9b5f9150316ff18f9c 354 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 183 314 1.1E-24 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS04795 0cbb11ba1173fd9b5f9150316ff18f9c 354 Pfam PF13426 PAS domain 26 128 2.1E-14 T 29-03-2018 IPR000014 PAS domain CB4_RS04795 0cbb11ba1173fd9b5f9150316ff18f9c 354 SMART SM00091 15 81 6.2E-6 T 29-03-2018 IPR000014 PAS domain CB4_RS04795 0cbb11ba1173fd9b5f9150316ff18f9c 354 Gene3D G3DSA:3.60.40.10 137 354 2.0E-17 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS04795 0cbb11ba1173fd9b5f9150316ff18f9c 354 SUPERFAMILY SSF81606 157 353 3.14E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS04795 0cbb11ba1173fd9b5f9150316ff18f9c 354 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 136 1.0E-20 T 29-03-2018 IPR000014 PAS domain CB4_RS04795 0cbb11ba1173fd9b5f9150316ff18f9c 354 SMART SM00331 153 353 3.8E-17 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS04795 0cbb11ba1173fd9b5f9150316ff18f9c 354 SUPERFAMILY SSF55785 20 127 2.27E-29 T 29-03-2018 IPR000014 PAS domain CB4_RS04795 0cbb11ba1173fd9b5f9150316ff18f9c 354 Gene3D G3DSA:3.30.450.20 17 136 7.2E-27 T 29-03-2018 CB4_RS08130 40fae2b653383c4ddf43d5eb1b5988e3 163 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 29 151 2.0E-16 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CB4_RS08130 40fae2b653383c4ddf43d5eb1b5988e3 163 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 5 153 1.4E-34 T 29-03-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ CB4_RS14445 fd566b0e83b39bcd3af1ee7b1fb88e9a 254 SMART SM00382 33 221 9.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS14445 fd566b0e83b39bcd3af1ee7b1fb88e9a 254 Pfam PF00005 ABC transporter 24 172 1.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS14445 fd566b0e83b39bcd3af1ee7b1fb88e9a 254 Gene3D G3DSA:3.40.50.300 1 239 2.1E-65 T 29-03-2018 CB4_RS14445 fd566b0e83b39bcd3af1ee7b1fb88e9a 254 SUPERFAMILY SSF52540 4 224 5.73E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07625 d509fdc3e61601bb0586e635e3d7d798 372 Pfam PF00437 Type II/IV secretion system protein 17 280 2.2E-73 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CB4_RS07625 d509fdc3e61601bb0586e635e3d7d798 372 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 208 222 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CB4_RS07625 d509fdc3e61601bb0586e635e3d7d798 372 Gene3D G3DSA:3.40.50.300 117 288 2.0E-36 T 29-03-2018 CB4_RS07625 d509fdc3e61601bb0586e635e3d7d798 372 Gene3D G3DSA:3.40.50.300 289 367 2.4E-4 T 29-03-2018 CB4_RS07625 d509fdc3e61601bb0586e635e3d7d798 372 SUPERFAMILY SSF52540 10 350 4.16E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07625 d509fdc3e61601bb0586e635e3d7d798 372 SMART SM00382 141 259 0.0077 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS07625 d509fdc3e61601bb0586e635e3d7d798 372 Gene3D G3DSA:3.30.450.90 2 113 3.9E-36 T 29-03-2018 CB4_RS07610 8279f7ffee45eb4825117cdd8fa93ce9 386 Pfam PF01966 HD domain 196 317 7.6E-20 T 29-03-2018 IPR006674 HD domain CB4_RS07610 8279f7ffee45eb4825117cdd8fa93ce9 386 Gene3D G3DSA:1.10.3210.10 149 360 3.2E-43 T 29-03-2018 CB4_RS07610 8279f7ffee45eb4825117cdd8fa93ce9 386 TIGRFAM TIGR00277 HDIG: HDIG domain 195 286 3.7E-8 T 29-03-2018 IPR006675 HDIG domain CB4_RS07610 8279f7ffee45eb4825117cdd8fa93ce9 386 SMART SM00471 191 326 8.1E-10 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS07610 8279f7ffee45eb4825117cdd8fa93ce9 386 SUPERFAMILY SSF109604 180 352 6.28E-34 T 29-03-2018 CB4_RS15490 9be42dad3b7596b097307367abce2a96 197 TIGRFAM TIGR02215 phage_chp_gp8: phage conserved hypothetical protein, phiE125 gp8 family 2 191 2.7E-31 T 29-03-2018 IPR011738 Phage conserved hypothetical protein CB4_RS15490 9be42dad3b7596b097307367abce2a96 197 Pfam PF05135 Phage gp6-like head-tail connector protein 12 57 6.8E-10 T 29-03-2018 IPR021146 Phage gp6-like head-tail connector protein CB4_RS15490 9be42dad3b7596b097307367abce2a96 197 Pfam PF05135 Phage gp6-like head-tail connector protein 150 195 2.6E-6 T 29-03-2018 IPR021146 Phage gp6-like head-tail connector protein CB4_RS20455 6037088a9a408d293ab1a07515ec0e94 199 PIRSF PIRSF006806 4 193 5.4E-47 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CB4_RS20455 6037088a9a408d293ab1a07515ec0e94 199 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 9 190 9.9E-51 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CB4_RS20455 6037088a9a408d293ab1a07515ec0e94 199 SUPERFAMILY SSF100950 8 196 1.81E-49 T 29-03-2018 CB4_RS20455 6037088a9a408d293ab1a07515ec0e94 199 Gene3D G3DSA:3.40.50.10420 1 195 4.9E-61 T 29-03-2018 CB4_RS20455 6037088a9a408d293ab1a07515ec0e94 199 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 9 190 2.6E-41 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CB4_RS14805 bccf0fea6ba1866fb7cc559873854e7a 528 Pfam PF00270 DEAD/DEAH box helicase 27 188 1.9E-51 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS14805 bccf0fea6ba1866fb7cc559873854e7a 528 Gene3D G3DSA:3.40.50.300 4 216 1.4E-62 T 29-03-2018 CB4_RS14805 bccf0fea6ba1866fb7cc559873854e7a 528 Pfam PF00271 Helicase conserved C-terminal domain 226 334 4.4E-31 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS14805 bccf0fea6ba1866fb7cc559873854e7a 528 SUPERFAMILY SSF52540 70 355 1.29E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14805 bccf0fea6ba1866fb7cc559873854e7a 528 SMART SM00487 21 217 6.8E-68 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS14805 bccf0fea6ba1866fb7cc559873854e7a 528 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 148 156 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CB4_RS14805 bccf0fea6ba1866fb7cc559873854e7a 528 Pfam PF03880 DbpA RNA binding domain 448 519 1.3E-17 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CB4_RS14805 bccf0fea6ba1866fb7cc559873854e7a 528 Gene3D G3DSA:3.40.50.300 217 514 1.3E-48 T 29-03-2018 CB4_RS14805 bccf0fea6ba1866fb7cc559873854e7a 528 SMART SM00490 253 334 1.1E-35 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS09135 fb1ee0cdece9274d6c681b273629891f 352 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 165 4.0E-37 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CB4_RS09135 fb1ee0cdece9274d6c681b273629891f 352 SUPERFAMILY SSF117143 91 261 4.32E-22 T 29-03-2018 CB4_RS09135 fb1ee0cdece9274d6c681b273629891f 352 SUPERFAMILY SSF117143 288 312 4.32E-22 T 29-03-2018 CB4_RS09135 fb1ee0cdece9274d6c681b273629891f 352 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 247 350 1.5E-18 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CB4_RS09135 fb1ee0cdece9274d6c681b273629891f 352 Pfam PF00460 Flagella basal body rod protein 5 35 2.9E-11 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 Gene3D G3DSA:1.10.287.130 194 273 5.7E-13 T 29-03-2018 CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 Gene3D G3DSA:3.30.565.10 280 425 3.0E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 SUPERFAMILY SSF55874 279 424 6.94E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 424 1.4E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 385 2.9E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 2.9E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 2.9E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 2.9E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 SUPERFAMILY SSF47384 205 276 3.14E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 SMART SM00387 320 425 1.9E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 SMART SM00388 211 277 1.2E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS18650 555701515d2693eee0cabdbe2bc173c4 425 Pfam PF00512 His Kinase A (phospho-acceptor) domain 213 276 2.0E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 SUPERFAMILY SSF52540 488 805 2.33E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 573 591 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Gene3D G3DSA:3.40.50.300 494 715 5.8E-57 T 29-03-2018 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 319 3.0E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 297 309 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Pfam PF02151 UvrB/uvrC motif 419 453 5.5E-5 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 6.5E-17 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 5.6E-18 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Gene3D G3DSA:1.10.8.60 347 489 5.6E-45 T 29-03-2018 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 SUPERFAMILY SSF81923 5 151 4.16E-33 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Gene3D G3DSA:1.10.1780.10 1 77 1.3E-24 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 SMART SM00382 202 346 2.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 SMART SM00382 539 717 3.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 SUPERFAMILY SSF52540 163 471 1.19E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Gene3D G3DSA:1.10.8.60 716 816 1.5E-24 T 29-03-2018 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Pfam PF07724 AAA domain (Cdc48 subfamily) 538 709 1.8E-55 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 SMART SM01086 716 805 4.5E-37 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Gene3D G3DSA:1.10.1780.10 78 194 7.7E-28 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 716 796 8.8E-26 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 Gene3D G3DSA:3.40.50.300 195 344 7.5E-20 T 29-03-2018 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 617 635 7.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 543 561 7.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 588 606 7.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS01255 11c8d38c388d2fc5c04ebaa4943d6c3a 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 664 7.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CB4_RS05585 725d47edf5fdfc3e4c653bef186f5fe9 254 SUPERFAMILY SSF55666 152 237 1.23E-23 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS05585 725d47edf5fdfc3e4c653bef186f5fe9 254 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 47.695 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CB4_RS05585 725d47edf5fdfc3e4c653bef186f5fe9 254 Pfam PF03725 3' exoribonuclease family, domain 2 159 224 3.0E-9 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS05585 725d47edf5fdfc3e4c653bef186f5fe9 254 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 1.7E-24 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS05585 725d47edf5fdfc3e4c653bef186f5fe9 254 Gene3D G3DSA:3.30.230.70 1 241 2.9E-60 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CB4_RS05585 725d47edf5fdfc3e4c653bef186f5fe9 254 SUPERFAMILY SSF54211 1 140 1.27E-45 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS05585 725d47edf5fdfc3e4c653bef186f5fe9 254 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site CB4_RS05585 725d47edf5fdfc3e4c653bef186f5fe9 254 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 2.1E-116 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CB4_RS14215 cf8994d7b8120f86233d1796e5cef27b 319 SUPERFAMILY SSF52540 9 50 1.56E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14215 cf8994d7b8120f86233d1796e5cef27b 319 SUPERFAMILY SSF52540 160 213 1.56E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14215 cf8994d7b8120f86233d1796e5cef27b 319 SUPERFAMILY SSF52540 260 280 1.56E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14215 cf8994d7b8120f86233d1796e5cef27b 319 Gene3D G3DSA:3.40.50.300 5 198 1.7E-63 T 29-03-2018 CB4_RS14215 cf8994d7b8120f86233d1796e5cef27b 319 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 293 1.1E-98 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CB4_RS14215 cf8994d7b8120f86233d1796e5cef27b 319 Gene3D G3DSA:1.10.287.890 202 283 5.7E-28 T 29-03-2018 CB4_RS14215 cf8994d7b8120f86233d1796e5cef27b 319 Pfam PF01715 IPP transferase 42 286 8.9E-83 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CB4_RS14215 cf8994d7b8120f86233d1796e5cef27b 319 SUPERFAMILY SSF52540 10 165 1.73E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14215 cf8994d7b8120f86233d1796e5cef27b 319 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 310 29.908 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 SUPERFAMILY SSF158472 178 227 1.44E-10 T 29-03-2018 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 Gene3D G3DSA:1.10.287.130 243 301 4.0E-18 T 29-03-2018 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 459 5.1E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 SMART SM00388 238 305 1.1E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 SUPERFAMILY SSF55874 294 459 1.96E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 SMART SM00387 351 462 2.2E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 Pfam PF00672 HAMP domain 178 227 1.6E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 SMART SM00304 178 230 4.4E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 SUPERFAMILY SSF47384 221 304 1.55E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 Gene3D G3DSA:3.30.450.20 17 152 1.5E-16 T 29-03-2018 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 Gene3D G3DSA:3.30.565.10 309 465 1.9E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 401 1.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 1.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 415 1.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 1.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 302 4.0E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS15920 9d3a5aeb43f50d4f00a5c33fc5cdb025 465 Gene3D G3DSA:3.30.450.20 200 242 3.4E-4 T 29-03-2018 CB4_RS12960 4c7717a3ef62312c4be35171950691c9 758 Gene3D G3DSA:2.60.40.10 215 294 7.6E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS12960 4c7717a3ef62312c4be35171950691c9 758 Gene3D G3DSA:2.60.40.680 424 595 6.1E-4 T 29-03-2018 CB4_RS12960 4c7717a3ef62312c4be35171950691c9 758 Pfam PF00395 S-layer homology domain 31 73 1.7E-8 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS12960 4c7717a3ef62312c4be35171950691c9 758 Pfam PF00395 S-layer homology domain 154 198 3.4E-10 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS12960 4c7717a3ef62312c4be35171950691c9 758 Pfam PF00395 S-layer homology domain 92 134 1.2E-8 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS04070 ca5033068ef9fc213e9aabda42167ec2 311 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 30 311 17.643 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CB4_RS04070 ca5033068ef9fc213e9aabda42167ec2 311 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 33 309 2.8E-91 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CB4_RS04070 ca5033068ef9fc213e9aabda42167ec2 311 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 85 107 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site CB4_RS04070 ca5033068ef9fc213e9aabda42167ec2 311 Pfam PF01040 UbiA prenyltransferase family 47 287 2.6E-59 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CB4_RS04710 e12ff160056d063db3098254150416d5 262 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 7 247 6.2E-112 T 29-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CB4_RS04710 e12ff160056d063db3098254150416d5 262 Gene3D G3DSA:3.40.50.300 4 253 2.8E-42 T 29-03-2018 CB4_RS04710 e12ff160056d063db3098254150416d5 262 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS04710 e12ff160056d063db3098254150416d5 262 SUPERFAMILY SSF52540 5 234 3.14E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS04710 e12ff160056d063db3098254150416d5 262 SMART SM00382 31 233 4.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS04710 e12ff160056d063db3098254150416d5 262 Pfam PF00005 ABC transporter 22 174 3.3E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS06480 a6d9f644a99450a9f139565968021aba 170 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 9 164 6.0E-43 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS06480 a6d9f644a99450a9f139565968021aba 170 ProSitePatterns PS00760 Signal peptidases I lysine active site. 80 92 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CB4_RS06480 a6d9f644a99450a9f139565968021aba 170 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 25 41 5.2E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS06480 a6d9f644a99450a9f139565968021aba 170 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 122 141 5.2E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS06480 a6d9f644a99450a9f139565968021aba 170 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 78 90 5.2E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS06480 a6d9f644a99450a9f139565968021aba 170 Gene3D G3DSA:2.10.109.10 21 170 6.2E-44 T 29-03-2018 CB4_RS06480 a6d9f644a99450a9f139565968021aba 170 Pfam PF00717 Peptidase S24-like 32 101 6.5E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CB4_RS06480 a6d9f644a99450a9f139565968021aba 170 SUPERFAMILY SSF51306 23 169 1.07E-46 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 Gene3D G3DSA:3.40.50.10090 373 482 8.1E-14 T 29-03-2018 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 Gene3D G3DSA:3.40.50.10090 259 370 1.1E-17 T 29-03-2018 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 Gene3D G3DSA:3.40.1010.10 2 127 4.7E-35 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 240 2.5E-93 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 216 1.6E-44 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 SUPERFAMILY SSF69618 253 478 8.37E-30 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 Gene3D G3DSA:3.30.950.10 128 258 4.8E-41 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 Pfam PF02602 Uroporphyrinogen-III synthase HemD 253 357 1.3E-9 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 Pfam PF02602 Uroporphyrinogen-III synthase HemD 382 475 9.5E-10 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 SUPERFAMILY SSF53790 1 255 9.29E-79 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 PIRSF PIRSF036426 1 256 1.6E-98 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CB4_RS01755 153e756b684f42277daf04b4daa351c9 486 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 83 116 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CB4_RS01775 7b1eb5650174e255a1633b8c4b7ff339 238 Gene3D G3DSA:3.40.1010.10 6 155 2.3E-31 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01775 7b1eb5650174e255a1633b8c4b7ff339 238 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 8 238 4.2E-81 T 29-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CB4_RS01775 7b1eb5650174e255a1633b8c4b7ff339 238 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 218 1.7E-50 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01775 7b1eb5650174e255a1633b8c4b7ff339 238 SUPERFAMILY SSF53790 2 237 1.57E-48 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01775 7b1eb5650174e255a1633b8c4b7ff339 238 PIRSF PIRSF036427 5 238 5.8E-75 T 29-03-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 CB4_RS02395 fc63fe3bb58442c8d7d4c48b4ea222cc 227 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 26 221 5.9E-63 T 29-03-2018 IPR003744 Queuosine precursor transporter CB4_RS02395 fc63fe3bb58442c8d7d4c48b4ea222cc 227 Pfam PF02592 Putative vitamin uptake transporter 57 217 5.5E-50 T 29-03-2018 IPR003744 Queuosine precursor transporter CB4_RS01545 7e2f9b8dfac13314bd354be7ea2fec99 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 190 206 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CB4_RS01545 7e2f9b8dfac13314bd354be7ea2fec99 255 PIRSF PIRSF005902 1 255 2.2E-91 T 29-03-2018 IPR001130 TatD family GO:0016788 CB4_RS01545 7e2f9b8dfac13314bd354be7ea2fec99 255 SUPERFAMILY SSF51556 2 255 6.82E-96 T 29-03-2018 IPR032466 Metal-dependent hydrolase CB4_RS01545 7e2f9b8dfac13314bd354be7ea2fec99 255 Pfam PF01026 TatD related DNase 3 253 6.6E-92 T 29-03-2018 IPR001130 TatD family GO:0016788 CB4_RS01545 7e2f9b8dfac13314bd354be7ea2fec99 255 Gene3D G3DSA:3.20.20.140 1 255 1.5E-97 T 29-03-2018 CB4_RS01545 7e2f9b8dfac13314bd354be7ea2fec99 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CB4_RS01545 7e2f9b8dfac13314bd354be7ea2fec99 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 254 2.8E-99 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 SUPERFAMILY SSF50494 65 286 5.55E-63 T 29-03-2018 IPR009003 Peptidase S1, PA clan CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 SMART SM00228 289 371 1.2E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 Gene3D G3DSA:2.30.42.10 284 383 9.5E-27 T 29-03-2018 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 Pfam PF13180 PDZ domain 290 380 1.1E-19 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 PRINTS PR00834 HtrA/DegQ protease family signature 246 263 2.0E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 PRINTS PR00834 HtrA/DegQ protease family signature 188 212 2.0E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 PRINTS PR00834 HtrA/DegQ protease family signature 125 137 2.0E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 PRINTS PR00834 HtrA/DegQ protease family signature 147 167 2.0E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 PRINTS PR00834 HtrA/DegQ protease family signature 224 241 2.0E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 PRINTS PR00834 HtrA/DegQ protease family signature 329 341 2.0E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 Gene3D G3DSA:2.40.10.10 61 183 9.0E-37 T 29-03-2018 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 Pfam PF13365 Trypsin-like peptidase domain 116 253 1.2E-33 T 29-03-2018 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 Gene3D G3DSA:2.40.10.10 184 279 3.9E-39 T 29-03-2018 CB4_RS07830 a9412c4afc598732a08ccc9834879c65 383 SUPERFAMILY SSF50156 270 378 4.99E-22 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00385 P450 superfamily signature 242 259 1.5E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00385 P450 superfamily signature 277 288 1.5E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00385 P450 superfamily signature 343 352 1.5E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00385 P450 superfamily signature 352 363 1.5E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 Pfam PF00067 Cytochrome P450 34 372 5.7E-35 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 Gene3D G3DSA:1.10.630.10 1 401 7.5E-87 T 29-03-2018 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00359 B-class P450 signature 196 218 3.8E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00359 B-class P450 signature 352 363 3.8E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00359 B-class P450 signature 277 288 3.8E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00359 B-class P450 signature 343 352 3.8E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00359 B-class P450 signature 153 168 3.8E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00359 B-class P450 signature 90 101 3.8E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00359 B-class P450 signature 136 152 3.8E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00359 B-class P450 signature 294 321 3.8E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 PRINTS PR00359 B-class P450 signature 322 337 3.8E-62 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CB4_RS13475 81bee4c4cfe33bf623749ded51e75bac 405 SUPERFAMILY SSF48264 13 403 8.38E-105 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CB4_RS02210 b34246a573770129602d5a176244fe8b 459 Pfam PF01050 Mannose-6-phosphate isomerase 298 442 6.1E-23 T 29-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CB4_RS02210 b34246a573770129602d5a176244fe8b 459 SUPERFAMILY SSF51182 187 441 1.12E-25 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS02210 b34246a573770129602d5a176244fe8b 459 Gene3D G3DSA:3.90.550.10 1 324 6.4E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS02210 b34246a573770129602d5a176244fe8b 459 Pfam PF00483 Nucleotidyl transferase 4 264 2.5E-30 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CB4_RS02210 b34246a573770129602d5a176244fe8b 459 Gene3D G3DSA:2.60.120.10 325 451 1.7E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS02210 b34246a573770129602d5a176244fe8b 459 SUPERFAMILY SSF53448 2 264 6.91E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 SUPERFAMILY SSF55174 343 420 5.76E-19 T 29-03-2018 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 70 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 17 419 2.9E-128 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 Gene3D G3DSA:1.10.240.10 237 328 1.3E-27 T 29-03-2018 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 Pfam PF00579 tRNA synthetases class I (W and Y) 50 336 1.1E-78 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 Gene3D G3DSA:3.10.290.10 329 421 1.1E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 196 218 1.1E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 179 194 1.1E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 229 241 1.1E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 64 86 1.1E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 SMART SM00363 359 421 3.2E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 SUPERFAMILY SSF52374 20 335 4.5E-93 T 29-03-2018 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 Gene3D G3DSA:3.40.50.620 13 236 9.9E-60 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 16 420 47.856 T 29-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 CB4_RS17290 e4db7336f08c4bb02c3ecdb9e3142fe7 421 Pfam PF01479 S4 domain 360 400 5.6E-6 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS10535 eb55327e2954da42792baef2b80e993c 319 SUPERFAMILY SSF56281 11 278 5.11E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS10535 eb55327e2954da42792baef2b80e993c 319 Pfam PF00753 Metallo-beta-lactamase superfamily 32 233 5.0E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS10535 eb55327e2954da42792baef2b80e993c 319 Gene3D G3DSA:3.60.15.10 1 289 1.2E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS10535 eb55327e2954da42792baef2b80e993c 319 SMART SM00849 28 233 1.9E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 SUPERFAMILY SSF46911 3 75 1.57E-29 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 Pfam PF01084 Ribosomal protein S18 20 71 6.9E-27 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 5 76 22.496 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 1.6E-36 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 Gene3D G3DSA:4.10.640.10 1 76 1.6E-33 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 76 8.0E-22 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 3.7E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 3.7E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 3.7E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS02010 395b4b24da75f9d91c7889728342d977 76 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 3.7E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS07065 c6059c390d75ae7d1fe60ead9b2ebb3f 147 Gene3D G3DSA:1.10.1510.10 1 90 7.2E-32 T 29-03-2018 CB4_RS07065 c6059c390d75ae7d1fe60ead9b2ebb3f 147 SUPERFAMILY SSF89095 1 147 5.75E-47 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CB4_RS07065 c6059c390d75ae7d1fe60ead9b2ebb3f 147 Gene3D G3DSA:1.10.10.410 91 147 9.0E-20 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CB4_RS07065 c6059c390d75ae7d1fe60ead9b2ebb3f 147 Pfam PF09424 Yqey-like protein 5 146 3.9E-58 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CB4_RS13885 46f73e5222fac64bcddd2ef472fbc04c 214 Pfam PF01895 PhoU domain 117 201 8.8E-17 T 29-03-2018 IPR026022 PhoU domain CB4_RS13885 46f73e5222fac64bcddd2ef472fbc04c 214 Pfam PF01895 PhoU domain 14 100 5.8E-19 T 29-03-2018 IPR026022 PhoU domain CB4_RS13885 46f73e5222fac64bcddd2ef472fbc04c 214 PIRSF PIRSF003107 3 214 1.1E-52 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CB4_RS13885 46f73e5222fac64bcddd2ef472fbc04c 214 Gene3D G3DSA:1.20.58.220 2 109 9.3E-23 T 29-03-2018 CB4_RS13885 46f73e5222fac64bcddd2ef472fbc04c 214 Gene3D G3DSA:1.20.58.220 115 214 9.4E-24 T 29-03-2018 CB4_RS13885 46f73e5222fac64bcddd2ef472fbc04c 214 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 209 1.4E-50 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CB4_RS13885 46f73e5222fac64bcddd2ef472fbc04c 214 SUPERFAMILY SSF109755 5 213 1.78E-54 T 29-03-2018 CB4_RS07710 83dd7ca7c690a22c6770729eadd9faed 263 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 105 132 2.8E-8 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CB4_RS07710 83dd7ca7c690a22c6770729eadd9faed 263 SUPERFAMILY SSF57716 107 136 1.01E-5 T 29-03-2018 CB4_RS07710 83dd7ca7c690a22c6770729eadd9faed 263 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 21 179 1.5E-54 T 29-03-2018 IPR014240 Regulatory protein, YteA family CB4_RS07710 83dd7ca7c690a22c6770729eadd9faed 263 SUPERFAMILY SSF109635 11 106 2.35E-13 T 29-03-2018 CB4_RS16260 cfdc01efd7a9dc951b4783a7334ce2e2 309 Gene3D G3DSA:1.10.3720.10 2 292 4.1E-40 T 29-03-2018 CB4_RS16260 cfdc01efd7a9dc951b4783a7334ce2e2 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 2.9E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS16260 cfdc01efd7a9dc951b4783a7334ce2e2 309 SUPERFAMILY SSF161098 88 286 5.56E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS09420 0b79417a78090a7eba9be67581447d76 83 Pfam PF05239 PRC-barrel domain 1 79 7.2E-17 T 29-03-2018 IPR027275 PRC-barrel domain CB4_RS09420 0b79417a78090a7eba9be67581447d76 83 Gene3D G3DSA:2.30.30.240 1 79 2.4E-18 T 29-03-2018 CB4_RS09420 0b79417a78090a7eba9be67581447d76 83 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 75 1.2E-26 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH CB4_RS09420 0b79417a78090a7eba9be67581447d76 83 SUPERFAMILY SSF50346 1 76 1.77E-14 T 29-03-2018 IPR011033 PRC-barrel-like CB4_RS06950 61a8744408fc5c1c0da5c2376df1f5ee 203 Pfam PF13702 Lysozyme-like 43 194 4.3E-50 T 29-03-2018 CB4_RS06950 61a8744408fc5c1c0da5c2376df1f5ee 203 SUPERFAMILY SSF53955 46 149 8.15E-11 T 29-03-2018 IPR023346 Lysozyme-like domain CB4_RS06950 61a8744408fc5c1c0da5c2376df1f5ee 203 Gene3D G3DSA:1.10.530.10 34 198 4.7E-14 T 29-03-2018 CB4_RS15480 39a120d1ed34762c4fd38452a9c03284 146 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 11 94 7.3E-5 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CB4_RS15480 39a120d1ed34762c4fd38452a9c03284 146 ProDom PD034535 XKDI PHAGE PHAGE-LIKE PBSX LIN1275 RELATED ELEMENT YQBI 33 95 3.0E-5 T 29-03-2018 CB4_RS08020 c04bd7f87df6a6e23f08cb32d21c1966 76 Pfam PF09388 Spo0E like sporulation regulatory protein 29 68 2.3E-11 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CB4_RS08020 c04bd7f87df6a6e23f08cb32d21c1966 76 SUPERFAMILY SSF140500 28 74 4.84E-8 T 29-03-2018 CB4_RS00825 0c0e2e17bc4742e8d815eecd168b8aa1 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site CB4_RS00825 0c0e2e17bc4742e8d815eecd168b8aa1 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 16 131 5.7E-59 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00825 0c0e2e17bc4742e8d815eecd168b8aa1 134 Gene3D G3DSA:3.30.420.80 8 134 1.6E-44 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CB4_RS00825 0c0e2e17bc4742e8d815eecd168b8aa1 134 SUPERFAMILY SSF53137 19 134 6.54E-50 T 29-03-2018 CB4_RS00825 0c0e2e17bc4742e8d815eecd168b8aa1 134 PIRSF PIRSF002131 2 134 2.5E-53 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CB4_RS00825 0c0e2e17bc4742e8d815eecd168b8aa1 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 5 134 34.166 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CB4_RS00825 0c0e2e17bc4742e8d815eecd168b8aa1 134 Pfam PF00411 Ribosomal protein S11 24 133 1.0E-50 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CB4_RS14565 fdb62d1aa599ca019d8b61a830a0c253 265 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 68 264 1.3E-57 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS14565 fdb62d1aa599ca019d8b61a830a0c253 265 Gene3D G3DSA:3.90.850.10 34 265 2.8E-72 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS14565 fdb62d1aa599ca019d8b61a830a0c253 265 Pfam PF10370 Domain of unknown function (DUF2437) 10 62 7.3E-5 T 29-03-2018 IPR018833 Domain of unknown function DUF2437 CB4_RS14565 fdb62d1aa599ca019d8b61a830a0c253 265 SUPERFAMILY SSF56529 60 265 6.8E-70 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS08565 142e8676cbeb7d384577a994ec70b0f5 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 5.9E-44 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CB4_RS08565 142e8676cbeb7d384577a994ec70b0f5 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 5.9E-44 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CB4_RS08565 142e8676cbeb7d384577a994ec70b0f5 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 5.9E-44 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CB4_RS08565 142e8676cbeb7d384577a994ec70b0f5 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 5.9E-44 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CB4_RS08565 142e8676cbeb7d384577a994ec70b0f5 163 Pfam PF01467 Cytidylyltransferase-like 6 134 8.0E-20 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CB4_RS08565 142e8676cbeb7d384577a994ec70b0f5 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 159 36.16 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CB4_RS08565 142e8676cbeb7d384577a994ec70b0f5 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 64 1.3E-18 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CB4_RS08565 142e8676cbeb7d384577a994ec70b0f5 163 SUPERFAMILY SSF52374 1 157 1.74E-44 T 29-03-2018 CB4_RS08565 142e8676cbeb7d384577a994ec70b0f5 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 158 1.9E-60 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CB4_RS08565 142e8676cbeb7d384577a994ec70b0f5 163 Gene3D G3DSA:3.40.50.620 1 159 2.5E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS01385 427be77c6b7fe5d5ce5af94de67f894e 284 PIRSF PIRSF006250 2 282 2.4E-101 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CB4_RS01385 427be77c6b7fe5d5ce5af94de67f894e 284 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 111 278 1.1E-65 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CB4_RS01385 427be77c6b7fe5d5ce5af94de67f894e 284 SUPERFAMILY SSF51690 111 279 6.67E-61 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CB4_RS01385 427be77c6b7fe5d5ce5af94de67f894e 284 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 20 109 3.7E-26 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CB4_RS01385 427be77c6b7fe5d5ce5af94de67f894e 284 Gene3D G3DSA:3.20.20.70 139 269 8.4E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS01385 427be77c6b7fe5d5ce5af94de67f894e 284 Gene3D G3DSA:3.90.1170.20 1 138 1.2E-44 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CB4_RS01385 427be77c6b7fe5d5ce5af94de67f894e 284 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 12 278 1.9E-107 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CB4_RS01385 427be77c6b7fe5d5ce5af94de67f894e 284 SUPERFAMILY SSF54675 2 110 1.77E-31 T 29-03-2018 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 93 6.5E-19 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 SUPERFAMILY SSF50615 11 95 3.53E-31 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 SUPERFAMILY SSF47917 373 500 1.07E-50 T 29-03-2018 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 Gene3D G3DSA:2.40.30.20 4 83 1.7E-39 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 Gene3D G3DSA:3.40.50.300 84 365 3.8E-122 T 29-03-2018 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 SUPERFAMILY SSF52540 96 371 2.63E-100 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 365 6.0E-73 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 PIRSF PIRSF039088 2 502 1.4E-258 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 Gene3D G3DSA:1.20.150.20 374 499 1.3E-53 T 29-03-2018 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 372 495 5.4E-50 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 500 52.166 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 356 365 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS02970 4b7a9cade6e9d9a67d2eb3d2a1ed7a82 503 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 4 500 4.8E-260 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS12425 62e1d20c49b8e18c45636ccc95003875 269 SUPERFAMILY SSF158430 3 127 5.62E-31 T 29-03-2018 CB4_RS12425 62e1d20c49b8e18c45636ccc95003875 269 SUPERFAMILY SSF158430 134 256 6.67E-26 T 29-03-2018 CB4_RS12425 62e1d20c49b8e18c45636ccc95003875 269 Pfam PF11155 Domain of unknown function (DUF2935) 8 122 4.6E-25 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CB4_RS12425 62e1d20c49b8e18c45636ccc95003875 269 Pfam PF11155 Domain of unknown function (DUF2935) 136 252 4.3E-21 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CB4_RS13160 33e128b0af7cc1b152886bb83f94913f 543 Pfam PF00005 ABC transporter 21 70 2.7E-10 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS13160 33e128b0af7cc1b152886bb83f94913f 543 Pfam PF00005 ABC transporter 103 134 5.9E-5 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS13160 33e128b0af7cc1b152886bb83f94913f 543 Pfam PF00005 ABC transporter 310 437 7.1E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS13160 33e128b0af7cc1b152886bb83f94913f 543 SUPERFAMILY SSF52540 3 209 6.89E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13160 33e128b0af7cc1b152886bb83f94913f 543 SMART SM00382 29 186 2.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13160 33e128b0af7cc1b152886bb83f94913f 543 SMART SM00382 318 516 1.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13160 33e128b0af7cc1b152886bb83f94913f 543 Pfam PF12848 ABC transporter 174 271 2.2E-9 T 29-03-2018 IPR032781 ABC-transporter extension domain CB4_RS13160 33e128b0af7cc1b152886bb83f94913f 543 SUPERFAMILY SSF52540 274 484 2.39E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13160 33e128b0af7cc1b152886bb83f94913f 543 Gene3D G3DSA:3.40.50.300 1 215 1.3E-43 T 29-03-2018 CB4_RS13160 33e128b0af7cc1b152886bb83f94913f 543 Gene3D G3DSA:3.40.50.300 253 501 2.0E-45 T 29-03-2018 CB4_RS05385 7bbe6c4c6e41383b369751e0c3d02b62 111 SUPERFAMILY SSF102829 13 90 1.96E-19 T 29-03-2018 IPR007838 Cell division protein ZapA-like CB4_RS05385 7bbe6c4c6e41383b369751e0c3d02b62 111 Pfam PF05164 Cell division protein ZapA 13 89 5.1E-19 T 29-03-2018 IPR007838 Cell division protein ZapA-like CB4_RS16095 e6b7a87a88627800ac104f1fad0b997b 747 Gene3D G3DSA:3.20.20.80 298 624 3.8E-55 T 29-03-2018 CB4_RS16095 e6b7a87a88627800ac104f1fad0b997b 747 SUPERFAMILY SSF49785 4 191 6.8E-35 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS16095 e6b7a87a88627800ac104f1fad0b997b 747 Gene3D G3DSA:2.60.120.260 1 190 1.0E-32 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS16095 e6b7a87a88627800ac104f1fad0b997b 747 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 38 126 2.3E-10 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CB4_RS16095 e6b7a87a88627800ac104f1fad0b997b 747 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 315 519 6.6E-14 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CB4_RS16095 e6b7a87a88627800ac104f1fad0b997b 747 Gene3D G3DSA:2.60.40.10 192 297 3.1E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS16095 e6b7a87a88627800ac104f1fad0b997b 747 Gene3D G3DSA:2.60.40.10 639 737 0.0016 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS16095 e6b7a87a88627800ac104f1fad0b997b 747 SUPERFAMILY SSF49303 193 305 3.74E-18 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CB4_RS16095 e6b7a87a88627800ac104f1fad0b997b 747 SUPERFAMILY SSF51445 303 626 7.58E-72 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CB4_RS16095 e6b7a87a88627800ac104f1fad0b997b 747 Pfam PF00703 Glycosyl hydrolases family 2 193 306 1.4E-15 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 Gene3D G3DSA:3.40.50.720 1 280 3.5E-75 T 29-03-2018 CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 37 277 3.6E-63 T 29-03-2018 CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 SUPERFAMILY SSF51735 25 277 3.7E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 195 5.2E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 164 5.2E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 102 113 5.2E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 102 113 8.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 8.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 8.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 8.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 28 45 8.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 166 8.7E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17180 ca1e537b8c63466098b002985768cf00 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 163 191 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CB4_RS14400 d01028c0a961a5ae5209cee7e4491f87 247 Gene3D G3DSA:3.40.50.300 1 246 6.1E-74 T 29-03-2018 CB4_RS14400 d01028c0a961a5ae5209cee7e4491f87 247 SUPERFAMILY SSF52540 3 242 4.21E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14400 d01028c0a961a5ae5209cee7e4491f87 247 SMART SM00382 28 220 1.3E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS14400 d01028c0a961a5ae5209cee7e4491f87 247 PIRSF PIRSF039085 1 247 1.4E-111 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CB4_RS14400 d01028c0a961a5ae5209cee7e4491f87 247 Pfam PF00005 ABC transporter 19 172 8.5E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS14400 d01028c0a961a5ae5209cee7e4491f87 247 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS02260 df52ec2f486fb3ac55296baddd989931 372 SMART SM00490 254 335 6.8E-35 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS02260 df52ec2f486fb3ac55296baddd989931 372 Gene3D G3DSA:3.40.50.300 11 217 1.7E-61 T 29-03-2018 CB4_RS02260 df52ec2f486fb3ac55296baddd989931 372 Pfam PF00271 Helicase conserved C-terminal domain 227 335 7.4E-32 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS02260 df52ec2f486fb3ac55296baddd989931 372 SMART SM00487 21 218 1.6E-61 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS02260 df52ec2f486fb3ac55296baddd989931 372 Gene3D G3DSA:3.40.50.300 218 371 3.8E-47 T 29-03-2018 CB4_RS02260 df52ec2f486fb3ac55296baddd989931 372 Pfam PF00270 DEAD/DEAH box helicase 26 191 8.8E-51 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS02260 df52ec2f486fb3ac55296baddd989931 372 SUPERFAMILY SSF52540 70 356 5.51E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 SUPERFAMILY SSF56024 329 508 2.79E-58 T 29-03-2018 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 SUPERFAMILY SSF143724 120 316 1.06E-57 T 29-03-2018 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 Pfam PF13090 Polyphosphate kinase C-terminal domain 343 689 1.7E-153 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 PIRSF PIRSF015589 1 702 4.5E-276 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 Pfam PF13089 Polyphosphate kinase N-terminal domain 17 122 3.6E-40 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 16 689 4.1E-276 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 Pfam PF02503 Polyphosphate kinase middle domain 132 333 2.3E-62 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 Gene3D G3DSA:3.30.870.10 331 512 4.1E-20 T 29-03-2018 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 SUPERFAMILY SSF56024 513 691 2.09E-69 T 29-03-2018 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 Gene3D G3DSA:1.20.58.310 19 121 1.5E-39 T 29-03-2018 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 Gene3D G3DSA:3.30.870.10 513 700 4.3E-32 T 29-03-2018 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 SUPERFAMILY SSF140356 15 119 7.46E-39 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 Gene3D G3DSA:3.30.1840.10 122 316 1.7E-62 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CB4_RS14365 f9c6056626b88b9718be13a7758f4024 702 Hamap MF_00347 Polyphosphate kinase [ppk]. 15 695 29.226 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CB4_RS19765 aa751ae77bbb67cc756598b40c59641c 337 Gene3D G3DSA:3.40.50.300 1 244 5.4E-78 T 29-03-2018 CB4_RS19765 aa751ae77bbb67cc756598b40c59641c 337 Pfam PF09383 NIL domain 260 332 2.5E-18 T 29-03-2018 IPR018449 NIL domain CB4_RS19765 aa751ae77bbb67cc756598b40c59641c 337 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS19765 aa751ae77bbb67cc756598b40c59641c 337 Pfam PF00005 ABC transporter 22 169 1.8E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS19765 aa751ae77bbb67cc756598b40c59641c 337 SUPERFAMILY SSF52540 1 240 5.32E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19765 aa751ae77bbb67cc756598b40c59641c 337 SMART SM00930 258 333 2.3E-24 T 29-03-2018 IPR018449 NIL domain CB4_RS19765 aa751ae77bbb67cc756598b40c59641c 337 Gene3D G3DSA:3.30.70.260 245 335 2.2E-22 T 29-03-2018 CB4_RS19765 aa751ae77bbb67cc756598b40c59641c 337 SMART SM00382 30 218 7.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS19765 aa751ae77bbb67cc756598b40c59641c 337 SUPERFAMILY SSF55021 249 334 8.81E-20 T 29-03-2018 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Pfam PF06580 Histidine kinase 842 921 1.7E-22 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 SUPERFAMILY SSF55874 897 1037 6.02E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 SUPERFAMILY SSF47384 442 520 2.16E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 PRINTS PR00344 Bacterial sensor protein C-terminal signature 661 674 4.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 PRINTS PR00344 Bacterial sensor protein C-terminal signature 636 654 4.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 PRINTS PR00344 Bacterial sensor protein C-terminal signature 600 614 4.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 PRINTS PR00344 Bacterial sensor protein C-terminal signature 618 628 4.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 SUPERFAMILY SSF49785 66 206 6.38E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 SUPERFAMILY SSF52172 707 841 4.13E-37 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Gene3D G3DSA:1.10.287.130 441 513 8.8E-12 T 29-03-2018 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 SMART SM00448 711 825 3.6E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 SUPERFAMILY SSF55874 509 675 2.62E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 940 1038 2.5E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 565 676 8.4E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 SMART SM00388 451 519 1.3E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Gene3D G3DSA:2.60.120.260 62 216 1.1E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 SMART SM00387 935 1039 3.8E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 SMART SM00387 564 677 1.5E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Gene3D G3DSA:3.30.565.10 831 1038 4.4E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Gene3D G3DSA:3.40.50.2300 705 830 1.8E-34 T 29-03-2018 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Pfam PF00512 His Kinase A (phospho-acceptor) domain 452 519 2.5E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Gene3D G3DSA:3.30.565.10 514 677 3.0E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Pfam PF00072 Response regulator receiver domain 713 826 4.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS02115 e65294e6b91e3a80a1a2324a7b25d0c0 1039 Pfam PF07695 7TM diverse intracellular signalling 229 430 1.4E-14 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 CB4_RS12195 e617c31bc0d9ee148a6efeff7b40534d 431 Pfam PF00534 Glycosyl transferases group 1 245 408 1.7E-39 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CB4_RS12195 e617c31bc0d9ee148a6efeff7b40534d 431 SUPERFAMILY SSF53756 49 431 1.2E-76 T 29-03-2018 CB4_RS12195 e617c31bc0d9ee148a6efeff7b40534d 431 Pfam PF13439 Glycosyltransferase Family 4 62 240 1.6E-15 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CB4_RS12195 e617c31bc0d9ee148a6efeff7b40534d 431 Gene3D G3DSA:3.40.50.2000 43 247 1.9E-6 T 29-03-2018 CB4_RS12195 e617c31bc0d9ee148a6efeff7b40534d 431 Gene3D G3DSA:3.40.50.2000 248 413 1.9E-44 T 29-03-2018 CB4_RS01950 2bd0fa7b7cbc6a6e62a06040d46ec924 275 Gene3D G3DSA:1.10.10.730 111 158 1.4E-19 T 29-03-2018 CB4_RS01950 2bd0fa7b7cbc6a6e62a06040d46ec924 275 SMART SM00470 21 110 5.0E-35 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CB4_RS01950 2bd0fa7b7cbc6a6e62a06040d46ec924 275 Gene3D G3DSA:3.90.1530.10 10 110 4.7E-36 T 29-03-2018 CB4_RS01950 2bd0fa7b7cbc6a6e62a06040d46ec924 275 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 19 271 1.2E-111 T 29-03-2018 IPR023705 Nucleoid occlusion protein CB4_RS01950 2bd0fa7b7cbc6a6e62a06040d46ec924 275 Pfam PF02195 ParB-like nuclease domain 23 109 3.0E-26 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CB4_RS01950 2bd0fa7b7cbc6a6e62a06040d46ec924 275 SUPERFAMILY SSF109709 104 211 6.28E-36 T 29-03-2018 CB4_RS01950 2bd0fa7b7cbc6a6e62a06040d46ec924 275 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 18 193 9.6E-59 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CB4_RS01950 2bd0fa7b7cbc6a6e62a06040d46ec924 275 SUPERFAMILY SSF110849 25 112 3.14E-29 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CB4_RS01440 f324b7e3b5f6305771be4516e1c5c7a6 95 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 11 95 1.0E-26 T 29-03-2018 IPR012504 Sporulation protein YabP CB4_RS01440 f324b7e3b5f6305771be4516e1c5c7a6 95 Pfam PF07873 YabP family 11 76 3.3E-21 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC CB4_RS01440 f324b7e3b5f6305771be4516e1c5c7a6 95 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 11 95 5.0E-30 T 29-03-2018 IPR012504 Sporulation protein YabP CB4_RS01440 f324b7e3b5f6305771be4516e1c5c7a6 95 PIRSF PIRSF011576 1 95 1.4E-37 T 29-03-2018 IPR012504 Sporulation protein YabP CB4_RS13610 d14f6428d15e0e797e0e076eea4eb655 191 Gene3D G3DSA:3.40.50.450 1 190 6.7E-57 T 29-03-2018 CB4_RS13610 d14f6428d15e0e797e0e076eea4eb655 191 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 179 5.0E-57 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CB4_RS13610 d14f6428d15e0e797e0e076eea4eb655 191 Pfam PF03641 Possible lysine decarboxylase 46 175 8.6E-42 T 29-03-2018 IPR031100 LOG family CB4_RS13610 d14f6428d15e0e797e0e076eea4eb655 191 SUPERFAMILY SSF102405 2 176 8.7E-60 T 29-03-2018 CB4_RS17885 252b21bf751920ef9bf68e2b76b05d9e 147 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 14 128 2.0E-15 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CB4_RS17885 252b21bf751920ef9bf68e2b76b05d9e 147 Pfam PF04284 Protein of unknown function (DUF441) 5 142 2.1E-40 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CB4_RS17885 252b21bf751920ef9bf68e2b76b05d9e 147 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 1 146 17.348 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 59.881 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 PIRSF PIRSF000538 2 495 2.4E-182 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 493 2.9E-226 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 251 1.5E-91 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 SUPERFAMILY SSF53067 254 493 8.06E-85 T 29-03-2018 CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 Gene3D G3DSA:3.30.420.40 1 247 9.7E-90 T 29-03-2018 CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 SUPERFAMILY SSF53067 4 254 2.53E-98 T 29-03-2018 CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 449 3.1E-65 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 Gene3D G3DSA:3.30.420.40 248 496 2.9E-79 T 29-03-2018 CB4_RS04680 902b8702e4cb85045533f1209969fb56 496 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CB4_RS20155 3f2352d493fb76ddecc0ff252e84dce3 292 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 127 1.6E-36 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CB4_RS20155 3f2352d493fb76ddecc0ff252e84dce3 292 SUPERFAMILY SSF111331 1 292 2.09E-87 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CB4_RS20155 3f2352d493fb76ddecc0ff252e84dce3 292 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 290 3.3E-95 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase CB4_RS20155 3f2352d493fb76ddecc0ff252e84dce3 292 Gene3D G3DSA:3.40.50.10330 1 131 2.8E-36 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CB4_RS20155 3f2352d493fb76ddecc0ff252e84dce3 292 SMART SM00046 3 130 3.1E-8 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Gene3D G3DSA:3.30.565.10 684 844 5.2E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Gene3D G3DSA:3.40.50.2300 871 997 4.1E-33 T 29-03-2018 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 738 843 9.1E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 SUPERFAMILY SSF103190 192 295 7.85E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Pfam PF00512 His Kinase A (phospho-acceptor) domain 621 689 1.9E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Pfam PF00072 Response regulator receiver domain 875 985 1.1E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Gene3D G3DSA:3.30.450.20 80 273 1.0E-15 T 29-03-2018 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 SUPERFAMILY SSF47384 605 690 5.49E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Pfam PF08448 PAS fold 500 602 1.2E-8 T 29-03-2018 IPR013656 PAS fold-4 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 SMART SM00388 621 689 8.8E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 SUPERFAMILY SSF52172 874 992 2.13E-32 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 489 607 3.3E-11 T 29-03-2018 IPR000014 PAS domain CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 SMART SM00448 873 987 1.8E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 PRINTS PR00344 Bacterial sensor protein C-terminal signature 807 825 5.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 PRINTS PR00344 Bacterial sensor protein C-terminal signature 831 844 5.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 PRINTS PR00344 Bacterial sensor protein C-terminal signature 775 789 5.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 PRINTS PR00344 Bacterial sensor protein C-terminal signature 793 803 5.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Gene3D G3DSA:1.10.287.130 614 683 5.5E-19 T 29-03-2018 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Gene3D G3DSA:3.30.450.20 274 402 4.1E-20 T 29-03-2018 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 SMART SM00387 737 847 1.1E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 SUPERFAMILY SSF55874 678 843 4.98E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Gene3D G3DSA:3.30.450.20 480 613 7.9E-21 T 29-03-2018 CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 SUPERFAMILY SSF55785 483 599 2.62E-14 T 29-03-2018 IPR000014 PAS domain CB4_RS14730 018c20f4961aab017da3f550b2c8a638 997 Pfam PF02743 Cache domain 90 385 7.8E-21 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS06585 b849a6f3685e2bdbbed0a141396cd48d 227 Gene3D G3DSA:1.10.150.280 169 227 1.5E-22 T 29-03-2018 CB4_RS06585 b849a6f3685e2bdbbed0a141396cd48d 227 Pfam PF10531 SLBB domain 87 140 6.6E-12 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS06585 b849a6f3685e2bdbbed0a141396cd48d 227 SMART SM00278 204 223 0.48 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CB4_RS06585 b849a6f3685e2bdbbed0a141396cd48d 227 SMART SM00278 174 193 0.018 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CB4_RS06585 b849a6f3685e2bdbbed0a141396cd48d 227 Gene3D G3DSA:3.10.560.10 73 168 4.7E-12 T 29-03-2018 CB4_RS06585 b849a6f3685e2bdbbed0a141396cd48d 227 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 164 226 2.7E-24 T 29-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CB4_RS06585 b849a6f3685e2bdbbed0a141396cd48d 227 SUPERFAMILY SSF47781 161 226 3.56E-29 T 29-03-2018 IPR010994 RuvA domain 2-like CB4_RS06585 b849a6f3685e2bdbbed0a141396cd48d 227 Pfam PF12836 Helix-hairpin-helix motif 163 225 1.4E-23 T 29-03-2018 CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Gene3D G3DSA:1.25.40.10 170 188 0.26 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Gene3D G3DSA:1.25.40.10 189 222 2.0E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 SUPERFAMILY SSF81901 142 297 2.03E-51 T 29-03-2018 CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 SMART SM00671 254 289 2.7E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 SMART SM00671 182 217 1.6E-12 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 SMART SM00671 110 145 8.0E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 SMART SM00671 74 109 1.5E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 SMART SM00671 218 253 1.3E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 SMART SM00671 146 181 1.8E-7 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 SUPERFAMILY SSF81901 62 149 2.07E-25 T 29-03-2018 CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Pfam PF08238 Sel1 repeat 255 289 5.0E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Pfam PF08238 Sel1 repeat 110 145 1.6E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Pfam PF08238 Sel1 repeat 182 216 4.8E-10 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Pfam PF08238 Sel1 repeat 221 251 1.1E-8 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Pfam PF08238 Sel1 repeat 76 109 2.9E-9 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Pfam PF08238 Sel1 repeat 146 178 2.0E-5 T 29-03-2018 IPR006597 Sel1-like repeat CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Gene3D G3DSA:2.60.40.1180 223 264 4.7E-22 T 29-03-2018 CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Gene3D G3DSA:2.60.40.1180 265 299 9.5E-15 T 29-03-2018 CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Gene3D G3DSA:2.60.40.1180 124 169 1.9E-22 T 29-03-2018 CB4_RS14080 87fae6dbfd449f6476566d51855f96e5 302 Gene3D G3DSA:2.60.40.1180 45 123 4.3E-25 T 29-03-2018 CB4_RS17070 1fb6c8af3989a65ac5e3a21eabaa9d49 362 Pfam PF00561 alpha/beta hydrolase fold 72 338 5.4E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS17070 1fb6c8af3989a65ac5e3a21eabaa9d49 362 SUPERFAMILY SSF53474 57 357 3.54E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS17070 1fb6c8af3989a65ac5e3a21eabaa9d49 362 TIGRFAM TIGR01836 PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit 10 360 3.4E-142 T 29-03-2018 IPR010125 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit GO:0016746|GO:0042619 CB4_RS17070 1fb6c8af3989a65ac5e3a21eabaa9d49 362 Gene3D G3DSA:3.40.50.1820 15 361 8.0E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS05850 e70f4a99b355e3e47a0221505a8c881e 480 SUPERFAMILY SSF50249 38 120 5.45E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS05850 e70f4a99b355e3e47a0221505a8c881e 480 Pfam PF10150 Ribonuclease E/G family 116 384 2.6E-103 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CB4_RS05850 e70f4a99b355e3e47a0221505a8c881e 480 Gene3D G3DSA:2.40.50.140 32 119 1.5E-28 T 29-03-2018 CB4_RS05850 e70f4a99b355e3e47a0221505a8c881e 480 SMART SM00316 36 114 4.0E-4 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS05850 e70f4a99b355e3e47a0221505a8c881e 480 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 12 418 1.4E-148 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CB4_RS06430 0a7a15b92703e762d2b62fcad9f465f3 261 SUPERFAMILY SSF55166 97 250 4.45E-39 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS06430 0a7a15b92703e762d2b62fcad9f465f3 261 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 113 242 2.2E-43 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CB4_RS06430 0a7a15b92703e762d2b62fcad9f465f3 261 Gene3D G3DSA:3.30.1380.10 80 253 7.5E-39 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 PIRSF PIRSF001369 1 370 4.1E-152 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 370 4.7E-162 T 29-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 Gene3D G3DSA:1.10.580.10 11 259 8.5E-89 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 PRINTS PR00143 Citrate synthase signature 193 221 1.3E-40 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 PRINTS PR00143 Citrate synthase signature 171 186 1.3E-40 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 PRINTS PR00143 Citrate synthase signature 323 337 1.3E-40 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 PRINTS PR00143 Citrate synthase signature 303 319 1.3E-40 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 PRINTS PR00143 Citrate synthase signature 122 135 1.3E-40 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 PRINTS PR00143 Citrate synthase signature 246 266 1.3E-40 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 Gene3D G3DSA:1.10.580.10 299 350 4.4E-11 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 ProSitePatterns PS00480 Citrate synthase signature. 253 265 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 SUPERFAMILY SSF48256 3 370 1.7E-136 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CB4_RS18395 f49c5429f79273890bc6335fbabf9d90 370 Pfam PF00285 Citrate synthase, C-terminal domain 6 353 1.0E-128 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CB4_RS10555 620fd2020c353b8b05b44f08c8ebad98 712 SUPERFAMILY SSF141868 458 705 1.83E-95 T 29-03-2018 IPR001633 EAL domain CB4_RS10555 620fd2020c353b8b05b44f08c8ebad98 712 Pfam PF00990 Diguanylate cyclase, GGDEF domain 281 437 1.1E-52 T 29-03-2018 IPR000160 GGDEF domain CB4_RS10555 620fd2020c353b8b05b44f08c8ebad98 712 SUPERFAMILY SSF55073 286 444 1.41E-50 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS10555 620fd2020c353b8b05b44f08c8ebad98 712 Gene3D G3DSA:3.20.20.450 446 712 2.4E-106 T 29-03-2018 IPR001633 EAL domain CB4_RS10555 620fd2020c353b8b05b44f08c8ebad98 712 SMART SM00267 270 442 1.3E-65 T 29-03-2018 IPR000160 GGDEF domain CB4_RS10555 620fd2020c353b8b05b44f08c8ebad98 712 Pfam PF17159 Membrane-associated sensor domain 39 266 1.0E-63 T 29-03-2018 IPR033425 Membrane-associated sensor domain MASE3 CB4_RS10555 620fd2020c353b8b05b44f08c8ebad98 712 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 278 440 2.2E-43 T 29-03-2018 IPR000160 GGDEF domain CB4_RS10555 620fd2020c353b8b05b44f08c8ebad98 712 Gene3D G3DSA:3.30.70.270 274 445 3.7E-59 T 29-03-2018 CB4_RS10555 620fd2020c353b8b05b44f08c8ebad98 712 SMART SM00052 452 698 1.8E-126 T 29-03-2018 IPR001633 EAL domain CB4_RS10555 620fd2020c353b8b05b44f08c8ebad98 712 Pfam PF00563 EAL domain 459 693 7.9E-75 T 29-03-2018 IPR001633 EAL domain CB4_RS16285 9b59dbd9595e0d3bc0feb9a0ebf58296 277 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 23 270 1.1E-108 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CB4_RS16285 9b59dbd9595e0d3bc0feb9a0ebf58296 277 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 23 269 3.5E-111 T 29-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CB4_RS16285 9b59dbd9595e0d3bc0feb9a0ebf58296 277 SUPERFAMILY SSF53167 7 275 2.09E-99 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CB4_RS16285 9b59dbd9595e0d3bc0feb9a0ebf58296 277 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 76 117 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CB4_RS16285 9b59dbd9595e0d3bc0feb9a0ebf58296 277 PIRSF PIRSF000477 2 272 4.8E-117 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CB4_RS16285 9b59dbd9595e0d3bc0feb9a0ebf58296 277 Pfam PF01048 Phosphorylase superfamily 24 269 1.7E-58 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CB4_RS16285 9b59dbd9595e0d3bc0feb9a0ebf58296 277 Gene3D G3DSA:3.40.50.1580 2 272 3.5E-74 T 29-03-2018 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 SUPERFAMILY SSF103190 66 185 3.66E-6 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 Pfam PF02743 Cache domain 49 269 1.7E-23 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 SMART SM00304 307 359 4.7E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 Pfam PF00672 HAMP domain 308 355 1.2E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 433 616 1.7E-37 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 Gene3D G3DSA:3.30.450.20 163 282 5.0E-19 T 29-03-2018 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 SMART SM00283 388 663 3.5E-57 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 SUPERFAMILY SSF58104 394 663 1.96E-68 T 29-03-2018 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 SUPERFAMILY SSF58104 327 361 1.96E-68 T 29-03-2018 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 Gene3D G3DSA:1.10.287.950 330 421 7.7E-8 T 29-03-2018 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 Gene3D G3DSA:1.10.287.950 422 664 9.6E-47 T 29-03-2018 CB4_RS13580 0b1f0b4b581b4d090cb815acd9bdcfcb 664 Gene3D G3DSA:3.30.450.20 54 162 2.8E-9 T 29-03-2018 CB4_RS20205 fca031a23e32502c518fc27f8a82ea9a 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 4.4E-28 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CB4_RS20205 fca031a23e32502c518fc27f8a82ea9a 96 SUPERFAMILY SSF141000 4 94 6.93E-32 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CB4_RS20205 fca031a23e32502c518fc27f8a82ea9a 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 25.247 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CB4_RS20205 fca031a23e32502c518fc27f8a82ea9a 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 2.1E-22 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CB4_RS05415 1c04aa851254b61ea2e9d60ec39295c6 455 Pfam PF00534 Glycosyl transferases group 1 251 408 6.3E-9 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CB4_RS05415 1c04aa851254b61ea2e9d60ec39295c6 455 Pfam PF13439 Glycosyltransferase Family 4 19 243 1.6E-11 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CB4_RS05415 1c04aa851254b61ea2e9d60ec39295c6 455 SUPERFAMILY SSF53756 118 409 2.3E-35 T 29-03-2018 CB4_RS05415 1c04aa851254b61ea2e9d60ec39295c6 455 SUPERFAMILY SSF53756 6 75 2.3E-35 T 29-03-2018 CB4_RS05415 1c04aa851254b61ea2e9d60ec39295c6 455 Gene3D G3DSA:3.40.50.2000 252 418 4.0E-16 T 29-03-2018 CB4_RS05415 1c04aa851254b61ea2e9d60ec39295c6 455 Gene3D G3DSA:3.40.50.2000 1 251 4.5E-15 T 29-03-2018 CB4_RS09280 af1b7d4fb154ce650a8a4d7ee246411c 257 Pfam PF01255 Putative undecaprenyl diphosphate synthase 35 255 2.0E-81 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CB4_RS09280 af1b7d4fb154ce650a8a4d7ee246411c 257 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 28 255 2.1E-86 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CB4_RS09280 af1b7d4fb154ce650a8a4d7ee246411c 257 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 28 256 40.753 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CB4_RS09280 af1b7d4fb154ce650a8a4d7ee246411c 257 SUPERFAMILY SSF64005 23 250 1.7E-87 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CB4_RS09280 af1b7d4fb154ce650a8a4d7ee246411c 257 Gene3D G3DSA:3.40.1180.10 17 257 2.4E-93 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CB4_RS09280 af1b7d4fb154ce650a8a4d7ee246411c 257 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 201 218 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CB4_RS09870 0aef1b964e96ec9188ed9f182d06385f 249 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS09870 0aef1b964e96ec9188ed9f182d06385f 249 SUPERFAMILY SSF55920 1 246 2.36E-87 T 29-03-2018 IPR000994 Peptidase M24 CB4_RS09870 0aef1b964e96ec9188ed9f182d06385f 249 Gene3D G3DSA:3.90.230.10 1 249 1.0E-83 T 29-03-2018 CB4_RS09870 0aef1b964e96ec9188ed9f182d06385f 249 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.5E-95 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS09870 0aef1b964e96ec9188ed9f182d06385f 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.2E-19 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS09870 0aef1b964e96ec9188ed9f182d06385f 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 1.2E-19 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS09870 0aef1b964e96ec9188ed9f182d06385f 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 1.2E-19 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS09870 0aef1b964e96ec9188ed9f182d06385f 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 1.2E-19 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS09870 0aef1b964e96ec9188ed9f182d06385f 249 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 40.189 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS09870 0aef1b964e96ec9188ed9f182d06385f 249 Pfam PF00557 Metallopeptidase family M24 11 239 1.6E-55 T 29-03-2018 IPR000994 Peptidase M24 CB4_RS14010 6747a0e76b3f06c27ddf3da5511b766f 93 Gene3D G3DSA:3.10.350.10 37 92 1.6E-13 T 29-03-2018 CB4_RS14010 6747a0e76b3f06c27ddf3da5511b766f 93 Pfam PF01476 LysM domain 40 90 3.3E-10 T 29-03-2018 IPR018392 LysM domain CB4_RS14010 6747a0e76b3f06c27ddf3da5511b766f 93 SUPERFAMILY SSF54106 41 90 3.27E-7 T 29-03-2018 IPR018392 LysM domain CB4_RS14010 6747a0e76b3f06c27ddf3da5511b766f 93 SMART SM00257 39 90 7.6E-5 T 29-03-2018 IPR018392 LysM domain CB4_RS13460 3ee872605de3726a49c3ebfc4ba43931 335 SUPERFAMILY SSF48208 30 319 6.8E-27 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CB4_RS13460 3ee872605de3726a49c3ebfc4ba43931 335 Gene3D G3DSA:1.50.10.10 23 324 1.6E-30 T 29-03-2018 CB4_RS12840 cca44e2205fb29bd31bf60289a241fcb 395 SUPERFAMILY SSF103473 4 374 7.59E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS12840 cca44e2205fb29bd31bf60289a241fcb 395 Gene3D G3DSA:1.20.1250.20 2 190 6.8E-22 T 29-03-2018 CB4_RS12840 cca44e2205fb29bd31bf60289a241fcb 395 Gene3D G3DSA:1.20.1250.20 191 376 7.0E-16 T 29-03-2018 CB4_RS12840 cca44e2205fb29bd31bf60289a241fcb 395 Pfam PF07690 Major Facilitator Superfamily 12 317 5.9E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS12630 007039c3a0ca8aa03794a99cf45b4075 144 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 121 139 4.8E-14 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CB4_RS12630 007039c3a0ca8aa03794a99cf45b4075 144 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 50 66 4.8E-14 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CB4_RS12630 007039c3a0ca8aa03794a99cf45b4075 144 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 26 42 4.8E-14 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CB4_RS12630 007039c3a0ca8aa03794a99cf45b4075 144 Pfam PF00210 Ferritin-like domain 6 143 1.7E-32 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CB4_RS12630 007039c3a0ca8aa03794a99cf45b4075 144 PIRSF PIRSF005900 1 144 2.9E-46 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CB4_RS12630 007039c3a0ca8aa03794a99cf45b4075 144 SUPERFAMILY SSF47240 3 144 4.64E-46 T 29-03-2018 IPR009078 Ferritin-like superfamily CB4_RS12630 007039c3a0ca8aa03794a99cf45b4075 144 ProSitePatterns PS00818 Dps protein family signature 1. 26 42 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CB4_RS12630 007039c3a0ca8aa03794a99cf45b4075 144 Gene3D G3DSA:1.20.1260.10 1 144 9.8E-48 T 29-03-2018 IPR012347 Ferritin-related CB4_RS07095 2884302ccc0e606db0b6f43bc6077ca8 705 Pfam PF07697 7TM-HD extracellular 51 260 1.7E-35 T 29-03-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain CB4_RS07095 2884302ccc0e606db0b6f43bc6077ca8 705 Pfam PF07698 7TM receptor with intracellular HD hydrolase 267 466 3.4E-44 T 29-03-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain CB4_RS07095 2884302ccc0e606db0b6f43bc6077ca8 705 TIGRFAM TIGR00277 HDIG: HDIG domain 488 586 9.7E-26 T 29-03-2018 IPR006675 HDIG domain CB4_RS07095 2884302ccc0e606db0b6f43bc6077ca8 705 SMART SM00471 487 643 2.5E-8 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS07095 2884302ccc0e606db0b6f43bc6077ca8 705 SUPERFAMILY SSF109604 490 663 1.41E-13 T 29-03-2018 CB4_RS07095 2884302ccc0e606db0b6f43bc6077ca8 705 Gene3D G3DSA:1.10.3210.10 438 679 2.3E-30 T 29-03-2018 CB4_RS07095 2884302ccc0e606db0b6f43bc6077ca8 705 Pfam PF01966 HD domain 491 633 1.3E-15 T 29-03-2018 IPR006674 HD domain CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 Gene3D G3DSA:1.20.1110.10 634 865 1.1E-31 T 29-03-2018 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 97 377 6.1E-38 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 570 696 2.5E-28 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 341 347 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 SUPERFAMILY SSF81660 334 515 1.18E-43 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 Pfam PF00690 Cation transporter/ATPase, N-terminus 21 84 8.2E-17 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 SUPERFAMILY SSF81665 240 333 3.79E-99 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 SUPERFAMILY SSF81665 656 864 3.79E-99 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 SUPERFAMILY SSF81665 19 127 3.79E-99 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 SUPERFAMILY SSF81653 127 239 1.83E-27 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 Gene3D G3DSA:3.40.50.1000 509 633 4.5E-34 T 29-03-2018 IPR023214 HAD-like domain CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 Pfam PF00122 E1-E2 ATPase 124 318 7.6E-44 T 29-03-2018 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 Gene3D G3DSA:3.40.1110.10 302 508 2.9E-40 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 7 866 0.0 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 PRINTS PR01836 Magnesium-transporting ATPase signature 269 288 2.7E-80 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 PRINTS PR01836 Magnesium-transporting ATPase signature 770 791 2.7E-80 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 PRINTS PR01836 Magnesium-transporting ATPase signature 373 386 2.7E-80 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 PRINTS PR01836 Magnesium-transporting ATPase signature 665 680 2.7E-80 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 PRINTS PR01836 Magnesium-transporting ATPase signature 715 728 2.7E-80 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 PRINTS PR01836 Magnesium-transporting ATPase signature 683 694 2.7E-80 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 PRINTS PR01836 Magnesium-transporting ATPase signature 735 751 2.7E-80 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 PRINTS PR01836 Magnesium-transporting ATPase signature 820 841 2.7E-80 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 PRINTS PR01836 Magnesium-transporting ATPase signature 252 268 2.7E-80 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 Gene3D G3DSA:2.70.150.10 25 241 3.5E-42 T 29-03-2018 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 Pfam PF00702 haloacid dehalogenase-like hydrolase 335 621 1.2E-18 T 29-03-2018 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 SMART SM00831 16 89 2.4E-19 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 SUPERFAMILY SSF56784 500 651 1.05E-36 T 29-03-2018 IPR023214 HAD-like domain CB4_RS17425 9d531b2e50c518f9d39c3258f50d78aa 867 Pfam PF00689 Cation transporting ATPase, C-terminus 690 857 1.5E-14 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CB4_RS04845 e8090bc06bd6b7fa039202ee3c76359e 25 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 2 25 8.8E-9 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CB4_RS04845 e8090bc06bd6b7fa039202ee3c76359e 25 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 3 25 1.2E-7 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 SUPERFAMILY SSF54991 711 807 2.22E-29 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 807 1.0E-274 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 SMART SM00896 714 807 7.6E-42 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 Gene3D G3DSA:3.30.70.380 711 807 5.0E-25 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 Gene3D G3DSA:3.30.930.10 497 701 4.3E-40 T 29-03-2018 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 Pfam PF03483 B3/4 domain 221 394 1.7E-70 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 801 46.331 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 Gene3D G3DSA:3.30.56.10 409 483 1.3E-24 T 29-03-2018 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 Pfam PF03484 tRNA synthetase B5 domain 414 479 3.0E-19 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 SUPERFAMILY SSF50249 37 198 2.69E-49 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 SMART SM00873 221 394 2.2E-96 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 SUPERFAMILY SSF46955 412 483 4.76E-19 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 Pfam PF01588 Putative tRNA binding domain 46 152 2.5E-25 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 Pfam PF03147 Ferredoxin-fold anticodon binding domain 714 807 2.4E-29 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 Gene3D G3DSA:3.30.56.10 1 197 1.8E-55 T 29-03-2018 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 SMART SM00874 411 479 3.7E-28 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 SUPERFAMILY SSF55681 475 701 4.97E-52 T 29-03-2018 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 Gene3D G3DSA:3.50.40.10 204 405 1.4E-77 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CB4_RS05380 7e6f8aacdbd0a5a0f702fe385deff73e 808 SUPERFAMILY SSF56037 209 402 9.94E-74 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CB4_RS18140 1a9ec9b08f0e9b7ccef70d54a379073e 174 SUPERFAMILY SSF54637 9 159 1.2E-45 T 29-03-2018 IPR029069 HotDog domain CB4_RS18140 1a9ec9b08f0e9b7ccef70d54a379073e 174 Gene3D G3DSA:3.10.129.10 2 161 3.7E-47 T 29-03-2018 CB4_RS18140 1a9ec9b08f0e9b7ccef70d54a379073e 174 Pfam PF03061 Thioesterase superfamily 30 104 8.4E-16 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS09940 88ef5c54c7ecaba9d7d5c47842a45fde 71 Gene3D G3DSA:2.10.230.10 7 62 1.5E-4 T 29-03-2018 CB4_RS09940 88ef5c54c7ecaba9d7d5c47842a45fde 71 SUPERFAMILY SSF57938 24 61 1.83E-5 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CB4_RS20480 015b5c0a205ce1d29e068207b6343a82 462 Gene3D G3DSA:3.30.450.20 84 165 1.3E-5 T 29-03-2018 CB4_RS20480 015b5c0a205ce1d29e068207b6343a82 462 Gene3D G3DSA:3.30.450.20 166 266 1.4E-11 T 29-03-2018 CB4_RS20480 015b5c0a205ce1d29e068207b6343a82 462 SMART SM00304 297 349 5.6E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS20480 015b5c0a205ce1d29e068207b6343a82 462 Pfam PF02743 Cache domain 43 259 2.6E-14 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS20480 015b5c0a205ce1d29e068207b6343a82 462 SUPERFAMILY SSF58104 384 456 7.32E-13 T 29-03-2018 CB4_RS20480 015b5c0a205ce1d29e068207b6343a82 462 SUPERFAMILY SSF58104 317 351 7.32E-13 T 29-03-2018 CB4_RS20480 015b5c0a205ce1d29e068207b6343a82 462 Pfam PF00672 HAMP domain 297 345 1.1E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS20480 015b5c0a205ce1d29e068207b6343a82 462 Gene3D G3DSA:1.10.287.950 404 459 0.0011 T 29-03-2018 CB4_RS20480 015b5c0a205ce1d29e068207b6343a82 462 Gene3D G3DSA:1.10.287.950 295 403 1.1E-10 T 29-03-2018 CB4_RS06590 5b538afc188e27e680e661f7a4949268 432 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 425 4.1E-150 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS06590 5b538afc188e27e680e661f7a4949268 432 SUPERFAMILY SSF53383 8 425 4.87E-135 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS06590 5b538afc188e27e680e661f7a4949268 432 Gene3D G3DSA:3.90.1150.10 293 431 5.2E-52 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS06590 5b538afc188e27e680e661f7a4949268 432 Gene3D G3DSA:3.40.640.10 1 288 6.2E-63 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS06590 5b538afc188e27e680e661f7a4949268 432 PIRSF PIRSF001434 1 428 7.3E-135 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS06590 5b538afc188e27e680e661f7a4949268 432 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS06590 5b538afc188e27e680e661f7a4949268 432 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 425 2.0E-214 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CB4_RS14090 738b66a7a2664f8b368315b4dcb84996 136 Pfam PF13411 MerR HTH family regulatory protein 13 78 8.0E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS14090 738b66a7a2664f8b368315b4dcb84996 136 Gene3D G3DSA:1.10.1660.10 66 120 1.8E-4 T 29-03-2018 CB4_RS14090 738b66a7a2664f8b368315b4dcb84996 136 SUPERFAMILY SSF46955 12 112 6.02E-21 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS14090 738b66a7a2664f8b368315b4dcb84996 136 SMART SM00422 12 80 9.3E-27 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS14090 738b66a7a2664f8b368315b4dcb84996 136 Gene3D G3DSA:1.10.1660.10 8 65 4.8E-19 T 29-03-2018 CB4_RS12810 e6711c372e4270b6fc3a1debe209dc62 33 SUPERFAMILY SSF46689 3 28 5.68E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS12810 e6711c372e4270b6fc3a1debe209dc62 33 Gene3D G3DSA:1.10.10.60 2 31 3.5E-6 T 29-03-2018 CB4_RS12810 e6711c372e4270b6fc3a1debe209dc62 33 Pfam PF02796 Helix-turn-helix domain of resolvase 2 30 2.9E-7 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CB4_RS06545 01bcd4ae26e0ffa4df3853ad0cd50d5f 199 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 10 73 1.6E-10 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CB4_RS06545 01bcd4ae26e0ffa4df3853ad0cd50d5f 199 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 8 198 30.59 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CB4_RS06545 01bcd4ae26e0ffa4df3853ad0cd50d5f 199 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 12 197 2.7E-52 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CB4_RS06545 01bcd4ae26e0ffa4df3853ad0cd50d5f 199 Gene3D G3DSA:3.40.50.620 3 198 8.1E-50 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS06545 01bcd4ae26e0ffa4df3853ad0cd50d5f 199 SUPERFAMILY SSF52374 6 198 9.38E-50 T 29-03-2018 CB4_RS06545 01bcd4ae26e0ffa4df3853ad0cd50d5f 199 Pfam PF01467 Cytidylyltransferase-like 12 170 2.4E-26 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 Gene3D G3DSA:3.30.1330.20 215 324 2.8E-46 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 Pfam PF12327 FtsZ family, C-terminal domain 222 316 2.7E-33 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 1.9E-42 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 372 39.461 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 PRINTS PR00423 Cell division protein FtsZ signature 189 211 5.6E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 PRINTS PR00423 Cell division protein FtsZ signature 98 118 5.6E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 PRINTS PR00423 Cell division protein FtsZ signature 126 147 5.6E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 PRINTS PR00423 Cell division protein FtsZ signature 212 233 5.6E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 SUPERFAMILY SSF55307 204 319 1.69E-43 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 330 5.6E-137 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 Gene3D G3DSA:3.40.50.1440 8 214 1.0E-45 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 SMART SM00864 13 205 2.2E-117 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 SMART SM00865 207 324 1.1E-54 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 SUPERFAMILY SSF52490 12 208 1.15E-71 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CB4_RS08295 ba6cb385fa599f79ea65e5152ce21353 396 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CB4_RS11440 6edb22ae2728d3b94d911b7724acef98 252 SUPERFAMILY SSF53067 144 244 1.1E-5 T 29-03-2018 CB4_RS11440 6edb22ae2728d3b94d911b7724acef98 252 SUPERFAMILY SSF53067 3 139 1.68E-11 T 29-03-2018 CB4_RS11440 6edb22ae2728d3b94d911b7724acef98 252 Gene3D G3DSA:3.30.420.40 1 160 1.5E-15 T 29-03-2018 CB4_RS16610 3f6c2e012fa6e7a237a05d2c50aac2b8 206 Gene3D G3DSA:1.20.58.220 99 205 6.5E-10 T 29-03-2018 CB4_RS16610 3f6c2e012fa6e7a237a05d2c50aac2b8 206 Pfam PF01865 Protein of unknown function DUF47 10 203 1.4E-26 T 29-03-2018 IPR018445 Putative phosphate transport regulator CB4_RS06235 e8aaa349bc54d907fd761930692a277c 377 Gene3D G3DSA:3.40.50.2000 11 202 8.7E-10 T 29-03-2018 CB4_RS06235 e8aaa349bc54d907fd761930692a277c 377 SUPERFAMILY SSF53756 64 374 2.55E-34 T 29-03-2018 CB4_RS06235 e8aaa349bc54d907fd761930692a277c 377 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 20 185 3.8E-25 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CB4_RS06235 e8aaa349bc54d907fd761930692a277c 377 Gene3D G3DSA:3.40.50.2000 203 364 1.7E-21 T 29-03-2018 CB4_RS06235 e8aaa349bc54d907fd761930692a277c 377 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 210 345 1.5E-8 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CB4_RS05320 842424e20dda571a7f05817a68cc39f7 510 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 496 4.2E-214 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS05320 842424e20dda571a7f05817a68cc39f7 510 SUPERFAMILY SSF110921 398 498 4.97E-20 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS05320 842424e20dda571a7f05817a68cc39f7 510 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 498 3.0E-36 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS05320 842424e20dda571a7f05817a68cc39f7 510 Pfam PF00682 HMGL-like 4 272 1.0E-94 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CB4_RS05320 842424e20dda571a7f05817a68cc39f7 510 SMART SM00917 368 499 2.5E-36 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS05320 842424e20dda571a7f05817a68cc39f7 510 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 508 42.84 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS05320 842424e20dda571a7f05817a68cc39f7 510 SUPERFAMILY SSF51569 2 290 5.13E-95 T 29-03-2018 CB4_RS05320 842424e20dda571a7f05817a68cc39f7 510 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS05320 842424e20dda571a7f05817a68cc39f7 510 Gene3D G3DSA:3.20.20.70 1 330 1.5E-108 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS05320 842424e20dda571a7f05817a68cc39f7 510 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CB4_RS11695 a7bd6045216c7ad2ee744e04106001d1 316 SUPERFAMILY SSF158499 199 268 9.81E-10 T 29-03-2018 IPR006343 DnaD domain CB4_RS11695 a7bd6045216c7ad2ee744e04106001d1 316 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 199 273 6.6E-14 T 29-03-2018 IPR006343 DnaD domain CB4_RS11695 a7bd6045216c7ad2ee744e04106001d1 316 Gene3D G3DSA:1.10.10.630 193 274 3.5E-14 T 29-03-2018 IPR034829 DnaD-like domain CB4_RS11695 a7bd6045216c7ad2ee744e04106001d1 316 Gene3D G3DSA:1.10.10.10 58 124 0.026 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS11695 a7bd6045216c7ad2ee744e04106001d1 316 Pfam PF07261 Replication initiation and membrane attachment 199 274 6.5E-11 T 29-03-2018 IPR006343 DnaD domain CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 PRINTS PR00415 Aconitase family signature 205 218 7.6E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 PRINTS PR00415 Aconitase family signature 295 308 7.6E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 PRINTS PR00415 Aconitase family signature 502 515 7.6E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 PRINTS PR00415 Aconitase family signature 172 180 7.6E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 PRINTS PR00415 Aconitase family signature 148 161 7.6E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 PRINTS PR00415 Aconitase family signature 374 388 7.6E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 PRINTS PR00415 Aconitase family signature 440 451 7.6E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 PRINTS PR00415 Aconitase family signature 219 234 7.6E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 PRINTS PR00415 Aconitase family signature 281 294 7.6E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 20 900 0.0 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 ProSitePatterns PS01244 Aconitase family signature 2. 502 515 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 Pfam PF00694 Aconitase C-terminal domain 701 828 1.1E-46 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 Gene3D G3DSA:3.30.499.10 374 585 9.2E-67 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 SUPERFAMILY SSF52016 639 900 6.47E-86 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 ProSitePatterns PS00450 Aconitase family signature 1. 436 452 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 Pfam PF00330 Aconitase family (aconitate hydratase) 79 571 7.2E-178 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 SUPERFAMILY SSF53732 20 636 3.66E-219 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 Gene3D G3DSA:3.40.1060.10 242 373 4.4E-46 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 Gene3D G3DSA:3.20.19.10 662 902 2.5E-88 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CB4_RS04175 9229e8c84f791f5d650e7a4d96180380 912 Gene3D G3DSA:3.30.499.10 39 241 3.9E-70 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS11705 4eb857e8bc02793ce2e7abcd0430e045 457 SUPERFAMILY SSF52540 185 256 8.57E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11705 4eb857e8bc02793ce2e7abcd0430e045 457 SUPERFAMILY SSF52540 292 399 8.57E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11705 4eb857e8bc02793ce2e7abcd0430e045 457 SUPERFAMILY SSF48024 9 75 7.85E-8 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CB4_RS11705 4eb857e8bc02793ce2e7abcd0430e045 457 Gene3D G3DSA:1.10.860.10 2 141 9.3E-8 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CB4_RS11705 4eb857e8bc02793ce2e7abcd0430e045 457 Pfam PF03796 DnaB-like helicase C terminal domain 189 376 6.4E-32 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CB4_RS11705 4eb857e8bc02793ce2e7abcd0430e045 457 Pfam PF00772 DnaB-like helicase N terminal domain 8 76 6.1E-8 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CB4_RS11705 4eb857e8bc02793ce2e7abcd0430e045 457 Gene3D G3DSA:3.40.50.300 180 454 1.6E-24 T 29-03-2018 CB4_RS17785 3f7d303c07a8164fee4e9caf25b97be8 159 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 31 152 1.6E-33 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CB4_RS17785 3f7d303c07a8164fee4e9caf25b97be8 159 SUPERFAMILY SSF55620 25 152 7.78E-38 T 29-03-2018 CB4_RS17785 3f7d303c07a8164fee4e9caf25b97be8 159 PIRSF PIRSF006113 26 153 2.0E-27 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CB4_RS17785 3f7d303c07a8164fee4e9caf25b97be8 159 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 31 120 1.5E-29 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CB4_RS17785 3f7d303c07a8164fee4e9caf25b97be8 159 Gene3D G3DSA:3.30.479.10 9 154 4.4E-39 T 29-03-2018 CB4_RS05075 84a2c6935ca63023a38143d506389ebc 149 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 27 127 2.9E-17 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CB4_RS05075 84a2c6935ca63023a38143d506389ebc 149 Pfam PF03061 Thioesterase superfamily 57 130 5.2E-11 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS05075 84a2c6935ca63023a38143d506389ebc 149 SUPERFAMILY SSF54637 23 138 3.89E-27 T 29-03-2018 IPR029069 HotDog domain CB4_RS05075 84a2c6935ca63023a38143d506389ebc 149 Gene3D G3DSA:3.10.129.10 4 142 4.2E-26 T 29-03-2018 CB4_RS10210 958ee4af0fd13b4d8ceb7d6772479843 74 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 7.0E-22 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CB4_RS10210 958ee4af0fd13b4d8ceb7d6772479843 74 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 26.243 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CB4_RS10210 958ee4af0fd13b4d8ceb7d6772479843 74 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 6.8E-35 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CB4_RS10210 958ee4af0fd13b4d8ceb7d6772479843 74 SMART SM01234 1 68 3.1E-49 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CB4_RS10210 958ee4af0fd13b4d8ceb7d6772479843 74 Pfam PF01809 Haemolytic domain 2 68 4.8E-32 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CB4_RS06575 7501cb3d60d80ea85ad6f4e9bc971500 278 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 158 258 1.1E-17 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CB4_RS06575 7501cb3d60d80ea85ad6f4e9bc971500 278 Gene3D G3DSA:1.10.3730.10 157 266 3.5E-20 T 29-03-2018 CB4_RS06575 7501cb3d60d80ea85ad6f4e9bc971500 278 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 269 17.347 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CB4_RS06575 7501cb3d60d80ea85ad6f4e9bc971500 278 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 95 1.2E-19 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CB4_RS06575 7501cb3d60d80ea85ad6f4e9bc971500 278 PIRSF PIRSF000193 1 263 2.4E-66 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CB4_RS06575 7501cb3d60d80ea85ad6f4e9bc971500 278 SUPERFAMILY SSF51735 1 155 1.02E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS06575 7501cb3d60d80ea85ad6f4e9bc971500 278 Gene3D G3DSA:3.40.50.720 1 156 2.1E-22 T 29-03-2018 CB4_RS06575 7501cb3d60d80ea85ad6f4e9bc971500 278 SUPERFAMILY SSF48179 157 259 1.56E-19 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS06575 7501cb3d60d80ea85ad6f4e9bc971500 278 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 219 241 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CB4_RS02340 582fa884fa23d08b5e897c3247b1d330 249 Pfam PF01171 PP-loop family 33 214 1.2E-19 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CB4_RS02340 582fa884fa23d08b5e897c3247b1d330 249 SUPERFAMILY SSF52402 11 224 1.46E-47 T 29-03-2018 CB4_RS02340 582fa884fa23d08b5e897c3247b1d330 249 Gene3D G3DSA:3.40.50.620 25 241 2.0E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS02340 582fa884fa23d08b5e897c3247b1d330 249 PIRSF PIRSF004976 4 245 3.1E-63 T 29-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 CB4_RS20745 3324a72b65ba324679d429577f669469 213 Gene3D G3DSA:3.40.50.720 1 209 1.1E-20 T 29-03-2018 CB4_RS20745 3324a72b65ba324679d429577f669469 213 SUPERFAMILY SSF51735 1 211 6.39E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS20745 3324a72b65ba324679d429577f669469 213 Pfam PF13460 NAD(P)H-binding 7 199 5.5E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS10640 081cb8f5eeeeed377de166cf2d94cc23 214 SUPERFAMILY SSF51391 5 208 2.09E-66 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10640 081cb8f5eeeeed377de166cf2d94cc23 214 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 10 211 28.573 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10640 081cb8f5eeeeed377de166cf2d94cc23 214 Gene3D G3DSA:3.20.20.70 1 211 1.8E-54 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS10640 081cb8f5eeeeed377de166cf2d94cc23 214 Pfam PF02581 Thiamine monophosphate synthase 12 193 9.2E-63 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS10640 081cb8f5eeeeed377de166cf2d94cc23 214 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 12 204 4.3E-66 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS00305 37762a99d27b3d75a0d7ec22805ebfd9 61 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 1.0E-7 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CB4_RS00305 37762a99d27b3d75a0d7ec22805ebfd9 61 Pfam PF08141 Small acid-soluble spore protein H family 1 58 2.5E-21 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CB4_RS00305 37762a99d27b3d75a0d7ec22805ebfd9 61 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 16.584 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CB4_RS00305 37762a99d27b3d75a0d7ec22805ebfd9 61 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 2.7E-18 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CB4_RS10350 a7d6fb7fe210d2126f147d376846d8fd 508 SUPERFAMILY SSF100950 227 496 3.63E-82 T 29-03-2018 CB4_RS10350 a7d6fb7fe210d2126f147d376846d8fd 508 SUPERFAMILY SSF100950 4 224 4.56E-66 T 29-03-2018 CB4_RS10350 a7d6fb7fe210d2126f147d376846d8fd 508 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 12 496 3.9E-228 T 29-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 CB4_RS10350 a7d6fb7fe210d2126f147d376846d8fd 508 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 324 465 1.7E-42 T 29-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain CB4_RS10350 a7d6fb7fe210d2126f147d376846d8fd 508 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 8 217 1.2E-22 T 29-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 CB4_RS10350 a7d6fb7fe210d2126f147d376846d8fd 508 Gene3D G3DSA:3.40.1080.10 13 242 7.5E-35 T 29-03-2018 CB4_RS10350 a7d6fb7fe210d2126f147d376846d8fd 508 Gene3D G3DSA:3.40.1080.10 243 501 1.5E-58 T 29-03-2018 CB4_RS18960 c10b13c106bc114d0021fcdeb0bd7002 222 SUPERFAMILY SSF52141 5 213 4.58E-41 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CB4_RS18960 c10b13c106bc114d0021fcdeb0bd7002 222 Pfam PF03167 Uracil DNA glycosylase superfamily 27 204 6.5E-35 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CB4_RS18960 c10b13c106bc114d0021fcdeb0bd7002 222 SMART SM00987 27 206 3.9E-24 T 29-03-2018 CB4_RS18960 c10b13c106bc114d0021fcdeb0bd7002 222 Gene3D G3DSA:3.40.470.10 2 219 1.4E-42 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CB4_RS18960 c10b13c106bc114d0021fcdeb0bd7002 222 SMART SM00986 27 206 3.9E-24 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 Gene3D G3DSA:3.90.930.12 2 82 6.2E-31 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 Gene3D G3DSA:3.90.930.12 83 178 3.0E-40 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 PRINTS PR00059 Ribosomal protein L6 signature 71 96 9.1E-35 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 PRINTS PR00059 Ribosomal protein L6 signature 99 115 9.1E-35 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 PRINTS PR00059 Ribosomal protein L6 signature 141 162 9.1E-35 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.7E-76 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 SUPERFAMILY SSF56053 1 82 3.84E-28 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 SUPERFAMILY SSF56053 83 177 1.08E-34 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 Pfam PF00347 Ribosomal protein L6 11 82 3.9E-23 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 Pfam PF00347 Ribosomal protein L6 90 164 9.6E-19 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 PIRSF PIRSF002162 1 177 5.0E-51 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00880 b133bea1e02a22a15166aee7862dd4ca 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 39.377 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 Gene3D G3DSA:1.10.287.130 320 388 6.5E-17 T 29-03-2018 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 528 1.8E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 493 1.8E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 507 1.8E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 547 1.8E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 Gene3D G3DSA:3.30.450.20 198 319 2.9E-15 T 29-03-2018 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 SUPERFAMILY SSF47384 323 391 8.24E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 Gene3D G3DSA:3.30.565.10 394 555 1.1E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 Gene3D G3DSA:3.30.450.40 15 197 1.7E-26 T 29-03-2018 IPR029016 GAF domain-like CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 SUPERFAMILY SSF55785 193 309 3.32E-11 T 29-03-2018 IPR000014 PAS domain CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 Pfam PF08448 PAS fold 209 311 2.0E-6 T 29-03-2018 IPR013656 PAS fold-4 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 Pfam PF13185 GAF domain 54 190 1.5E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 SMART SM00388 326 392 1.4E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 SMART SM00387 434 550 8.9E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 438 548 6.4E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 SUPERFAMILY SSF55874 382 551 1.44E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 Pfam PF00512 His Kinase A (phospho-acceptor) domain 328 391 4.7E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 SMART SM00065 54 199 2.2E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 CB4_RS10595 c2ad9a06633f5b793ce7296b47108e13 565 SUPERFAMILY SSF55781 56 200 2.16E-23 T 29-03-2018 IPR029016 GAF domain-like CB4_RS17365 3beebee7caf7e39c267c1f6c31a81006 359 Gene3D G3DSA:3.40.718.10 1 350 2.2E-84 T 29-03-2018 CB4_RS17365 3beebee7caf7e39c267c1f6c31a81006 359 SUPERFAMILY SSF53659 1 345 1.08E-74 T 29-03-2018 CB4_RS17365 3beebee7caf7e39c267c1f6c31a81006 359 SMART SM01329 4 342 5.8E-70 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CB4_RS17365 3beebee7caf7e39c267c1f6c31a81006 359 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 342 1.4E-52 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CB4_RS05330 b83b3df9e9abee0f3804ed49c9037676 590 Pfam PF02310 B12 binding domain 8 122 4.6E-21 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CB4_RS05330 b83b3df9e9abee0f3804ed49c9037676 590 Gene3D G3DSA:3.40.50.280 1 125 1.2E-13 T 29-03-2018 CB4_RS05330 b83b3df9e9abee0f3804ed49c9037676 590 SUPERFAMILY SSF102114 159 380 2.62E-39 T 29-03-2018 CB4_RS05330 b83b3df9e9abee0f3804ed49c9037676 590 Gene3D G3DSA:3.80.30.20 175 389 2.2E-25 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CB4_RS05330 b83b3df9e9abee0f3804ed49c9037676 590 SUPERFAMILY SSF52242 41 149 4.51E-11 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CB4_RS05330 b83b3df9e9abee0f3804ed49c9037676 590 Pfam PF04055 Radical SAM superfamily 181 343 1.9E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS05330 b83b3df9e9abee0f3804ed49c9037676 590 Pfam PF13311 Protein of unknown function (DUF4080) 370 551 2.1E-47 T 29-03-2018 IPR025288 Domain of unknown function DUF4080 CB4_RS05330 b83b3df9e9abee0f3804ed49c9037676 590 SMART SM00729 176 388 1.9E-22 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS08475 5955b1f6c353bd88d255af817cc9602d 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 367 5.7E-71 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CB4_RS08475 5955b1f6c353bd88d255af817cc9602d 401 Gene3D G3DSA:3.40.50.10300 183 401 1.2E-69 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CB4_RS08475 5955b1f6c353bd88d255af817cc9602d 401 Gene3D G3DSA:3.40.50.1950 1 182 4.7E-50 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CB4_RS08475 5955b1f6c353bd88d255af817cc9602d 401 SUPERFAMILY SSF102645 185 396 1.57E-74 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CB4_RS08475 5955b1f6c353bd88d255af817cc9602d 401 SUPERFAMILY SSF52507 2 177 6.15E-60 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CB4_RS08475 5955b1f6c353bd88d255af817cc9602d 401 Pfam PF02441 Flavoprotein 4 175 3.4E-43 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CB4_RS08475 5955b1f6c353bd88d255af817cc9602d 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 1 393 1.6E-145 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CB4_RS02790 d1d3966769bc712daec96bd14fb4aeb2 176 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 18 170 12.442 T 29-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CB4_RS02790 d1d3966769bc712daec96bd14fb4aeb2 176 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 21 99 1.5E-30 T 29-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CB4_RS02790 d1d3966769bc712daec96bd14fb4aeb2 176 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 25 90 3.9E-8 T 29-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 CB4_RS00220 c6dee6fbc4fe8c50697b267ee2cbd7a0 461 Pfam PF00202 Aminotransferase class-III 74 450 2.7E-107 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS00220 c6dee6fbc4fe8c50697b267ee2cbd7a0 461 Gene3D G3DSA:3.90.1150.10 342 453 2.0E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS00220 c6dee6fbc4fe8c50697b267ee2cbd7a0 461 Gene3D G3DSA:3.90.1150.10 39 221 6.5E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS00220 c6dee6fbc4fe8c50697b267ee2cbd7a0 461 SUPERFAMILY SSF53383 70 453 3.19E-122 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS00220 c6dee6fbc4fe8c50697b267ee2cbd7a0 461 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 269 306 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS00220 c6dee6fbc4fe8c50697b267ee2cbd7a0 461 Gene3D G3DSA:3.40.640.10 222 341 4.5E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS00220 c6dee6fbc4fe8c50697b267ee2cbd7a0 461 TIGRFAM TIGR03372 putres_am_tran: putrescine aminotransferase 11 449 6.3E-210 T 29-03-2018 IPR017747 Putrescine aminotransferase GO:0009447|GO:0030170|GO:0033094 KEGG: 00330+2.6.1.82|MetaCyc: PWY-2|MetaCyc: PWY-6440 CB4_RS00220 c6dee6fbc4fe8c50697b267ee2cbd7a0 461 PIRSF PIRSF000521 173 453 2.7E-41 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS00220 c6dee6fbc4fe8c50697b267ee2cbd7a0 461 PIRSF PIRSF000521 12 179 2.0E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS01170 1f7e7f85d58d2709307d2e10558ca75d 69 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 13 41 - T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CB4_RS01170 1f7e7f85d58d2709307d2e10558ca75d 69 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 13 64 3.6E-20 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CB4_RS01170 1f7e7f85d58d2709307d2e10558ca75d 69 Gene3D G3DSA:1.20.5.1030 12 61 2.9E-21 T 29-03-2018 CB4_RS01170 1f7e7f85d58d2709307d2e10558ca75d 69 Hamap MF_00422 Protein translocase subunit SecE [secE]. 5 63 12.963 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CB4_RS01170 1f7e7f85d58d2709307d2e10558ca75d 69 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 13 66 5.0E-20 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CB4_RS09980 c01513985f824eca456b8fe32445f3db 148 SMART SM00347 26 126 1.7E-30 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09980 c01513985f824eca456b8fe32445f3db 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 4.1E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09980 c01513985f824eca456b8fe32445f3db 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 4.1E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09980 c01513985f824eca456b8fe32445f3db 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 4.1E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09980 c01513985f824eca456b8fe32445f3db 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 4.1E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09980 c01513985f824eca456b8fe32445f3db 148 Gene3D G3DSA:1.10.10.10 1 148 2.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09980 c01513985f824eca456b8fe32445f3db 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CB4_RS09980 c01513985f824eca456b8fe32445f3db 148 SUPERFAMILY SSF46785 5 143 1.9E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09980 c01513985f824eca456b8fe32445f3db 148 Pfam PF01047 MarR family 33 90 3.3E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS03260 6bcab94274d60db92758b70d12fd0f22 372 Gene3D G3DSA:1.20.1600.10 258 365 1.2E-12 T 29-03-2018 CB4_RS03260 6bcab94274d60db92758b70d12fd0f22 372 Gene3D G3DSA:1.20.1600.10 21 257 2.4E-19 T 29-03-2018 CB4_RS03260 6bcab94274d60db92758b70d12fd0f22 372 SUPERFAMILY SSF56954 5 254 3.92E-25 T 29-03-2018 CB4_RS03260 6bcab94274d60db92758b70d12fd0f22 372 SUPERFAMILY SSF56954 266 362 8.37E-12 T 29-03-2018 CB4_RS03260 6bcab94274d60db92758b70d12fd0f22 372 Pfam PF02321 Outer membrane efflux protein 93 201 1.5E-8 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CB4_RS03260 6bcab94274d60db92758b70d12fd0f22 372 Pfam PF02321 Outer membrane efflux protein 264 353 4.6E-10 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 SMART SM00846 2 151 7.0E-98 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 4.0E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 4.0E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 4.0E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 4.0E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 4.0E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 PIRSF PIRSF000149 1 333 9.3E-145 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 SUPERFAMILY SSF51735 2 178 1.02E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 Gene3D G3DSA:3.40.50.720 1 160 1.3E-80 T 29-03-2018 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 312 4.7E-71 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 101 1.7E-40 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 SUPERFAMILY SSF55347 151 313 1.71E-74 T 29-03-2018 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 Gene3D G3DSA:3.30.360.10 161 314 1.1E-70 T 29-03-2018 CB4_RS03855 c6b9492dce6209144f0565433ecc5acf 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 7.6E-140 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 Pfam PF00672 HAMP domain 182 230 8.6E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 SUPERFAMILY SSF47384 218 299 5.69E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 299 5.7E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 SUPERFAMILY SSF158472 182 231 5.75E-9 T 29-03-2018 CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 Gene3D G3DSA:3.30.565.10 284 449 1.8E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 445 7.7E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 SMART SM00387 344 449 2.6E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 SUPERFAMILY SSF55874 305 447 9.04E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 SMART SM00388 235 301 3.0E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 SMART SM00304 182 234 1.6E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS09990 edbd8b983a176cd67a5fc5de2a300530 450 Gene3D G3DSA:1.10.287.130 225 283 2.1E-13 T 29-03-2018 CB4_RS12125 ad0b9fc7743e3c447f366a49f9dd696d 186 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 9.4E-11 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS12125 ad0b9fc7743e3c447f366a49f9dd696d 186 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 53 63 9.4E-11 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS12125 ad0b9fc7743e3c447f366a49f9dd696d 186 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 98 106 9.4E-11 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS12125 ad0b9fc7743e3c447f366a49f9dd696d 186 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 1.5E-7 T 29-03-2018 CB4_RS12125 ad0b9fc7743e3c447f366a49f9dd696d 186 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.5E-7 T 29-03-2018 CB4_RS12125 ad0b9fc7743e3c447f366a49f9dd696d 186 Gene3D G3DSA:3.50.50.60 1 183 1.3E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS12125 ad0b9fc7743e3c447f366a49f9dd696d 186 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 56 160 2.9E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS12125 ad0b9fc7743e3c447f366a49f9dd696d 186 Pfam PF03486 HI0933-like protein 2 40 2.1E-7 T 29-03-2018 CB4_RS12125 ad0b9fc7743e3c447f366a49f9dd696d 186 SUPERFAMILY SSF51905 1 175 9.72E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17415 268ccc9fc268240a8d669cc4e6c3428c 257 SMART SM00116 146 199 0.001 T 29-03-2018 IPR000644 CBS domain CB4_RS17415 268ccc9fc268240a8d669cc4e6c3428c 257 SMART SM00116 210 257 0.019 T 29-03-2018 IPR000644 CBS domain CB4_RS17415 268ccc9fc268240a8d669cc4e6c3428c 257 Gene3D G3DSA:1.25.60.10 3 127 1.8E-18 T 29-03-2018 CB4_RS17415 268ccc9fc268240a8d669cc4e6c3428c 257 Gene3D G3DSA:3.10.580.10 128 257 4.3E-23 T 29-03-2018 CB4_RS17415 268ccc9fc268240a8d669cc4e6c3428c 257 Pfam PF03448 MgtE intracellular N domain 36 135 1.1E-21 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CB4_RS17415 268ccc9fc268240a8d669cc4e6c3428c 257 SUPERFAMILY SSF158791 10 134 6.28E-26 T 29-03-2018 CB4_RS17415 268ccc9fc268240a8d669cc4e6c3428c 257 SMART SM00924 36 139 1.1E-18 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CB4_RS17415 268ccc9fc268240a8d669cc4e6c3428c 257 Pfam PF00571 CBS domain 139 197 2.2E-9 T 29-03-2018 IPR000644 CBS domain CB4_RS17415 268ccc9fc268240a8d669cc4e6c3428c 257 Pfam PF00571 CBS domain 203 257 4.0E-9 T 29-03-2018 IPR000644 CBS domain CB4_RS17415 268ccc9fc268240a8d669cc4e6c3428c 257 SUPERFAMILY SSF54631 139 257 7.96E-31 T 29-03-2018 CB4_RS06295 fe93f4c58bb3e96b48afbb1b5b750ba3 129 Pfam PF13650 Aspartyl protease 19 108 4.1E-11 T 29-03-2018 CB4_RS06295 fe93f4c58bb3e96b48afbb1b5b750ba3 129 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 28 39 - T 29-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 CB4_RS06295 fe93f4c58bb3e96b48afbb1b5b750ba3 129 Gene3D G3DSA:2.40.70.10 1 118 1.6E-12 T 29-03-2018 IPR021109 Aspartic peptidase domain CB4_RS06295 fe93f4c58bb3e96b48afbb1b5b750ba3 129 SUPERFAMILY SSF50630 25 117 1.29E-6 T 29-03-2018 IPR021109 Aspartic peptidase domain CB4_RS04360 2f975d17459c3c304a8b41979f9e0ff5 215 Gene3D G3DSA:2.60.40.1120 79 171 4.3E-4 T 29-03-2018 CB4_RS09405 05f19f62387ee00884ef34c048b9f7ea 439 SUPERFAMILY SSF56801 157 266 1.07E-8 T 29-03-2018 CB4_RS09405 05f19f62387ee00884ef34c048b9f7ea 439 TIGRFAM TIGR02304 aden_form_hyp: putative adenylate-forming enzyme 3 434 7.9E-150 T 29-03-2018 IPR012685 Conserved hypothetical protein CHP02304, F390 synthetase-related CB4_RS09405 05f19f62387ee00884ef34c048b9f7ea 439 Gene3D G3DSA:3.40.50.980 101 263 2.0E-9 T 29-03-2018 CB4_RS09405 05f19f62387ee00884ef34c048b9f7ea 439 Pfam PF00501 AMP-binding enzyme 158 267 6.0E-6 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS11270 e23dc1c7f3a977097c0cf0a33bca0ae6 223 Gene3D G3DSA:3.30.420.10 54 219 8.2E-21 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS11270 e23dc1c7f3a977097c0cf0a33bca0ae6 223 Pfam PF13456 Reverse transcriptase-like 80 206 8.4E-12 T 29-03-2018 CB4_RS11270 e23dc1c7f3a977097c0cf0a33bca0ae6 223 SUPERFAMILY SSF53098 76 209 7.71E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 Gene3D G3DSA:2.60.40.420 23 184 1.3E-38 T 29-03-2018 IPR008972 Cupredoxin CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 SUPERFAMILY SSF49503 187 353 2.39E-27 T 29-03-2018 IPR008972 Cupredoxin CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 Pfam PF00394 Multicopper oxidase 191 330 2.1E-13 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 Gene3D G3DSA:2.60.40.420 187 372 1.9E-32 T 29-03-2018 IPR008972 Cupredoxin CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 ProSitePatterns PS00080 Multicopper oxidases signature 2. 486 497 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 SUPERFAMILY SSF49503 65 186 1.15E-39 T 29-03-2018 IPR008972 Cupredoxin CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 Pfam PF07732 Multicopper oxidase 73 183 5.8E-37 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 Pfam PF07731 Multicopper oxidase 395 501 1.5E-31 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 ProSitePatterns PS00079 Multicopper oxidases signature 1. 481 501 - T 29-03-2018 IPR033138 Multicopper oxidases, conserved site CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 Gene3D G3DSA:2.60.40.420 373 519 1.7E-38 T 29-03-2018 IPR008972 Cupredoxin CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 SUPERFAMILY SSF49503 393 500 6.27E-36 T 29-03-2018 IPR008972 Cupredoxin CB4_RS12485 d3edfad9695878ad6ee93b42244be43a 521 SUPERFAMILY SSF49503 342 365 6.27E-36 T 29-03-2018 IPR008972 Cupredoxin CB4_RS13120 0367ba1163ee8e8aa9d0f27feb2aacf8 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 296 8.6E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS13120 0367ba1163ee8e8aa9d0f27feb2aacf8 303 SUPERFAMILY SSF161098 83 279 1.96E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS13120 0367ba1163ee8e8aa9d0f27feb2aacf8 303 Gene3D G3DSA:1.10.3720.10 1 285 1.2E-38 T 29-03-2018 CB4_RS02640 9ec850f1fb01700f5537ad4877746c08 289 Pfam PF01522 Polysaccharide deacetylase 90 240 5.9E-25 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS02640 9ec850f1fb01700f5537ad4877746c08 289 Gene3D G3DSA:3.20.20.370 43 287 3.9E-40 T 29-03-2018 CB4_RS02640 9ec850f1fb01700f5537ad4877746c08 289 SUPERFAMILY SSF88713 55 254 5.99E-36 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS04735 4d4eceb852d4542f253cdfed31276560 124 Gene3D G3DSA:1.10.443.10 1 116 1.8E-23 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS04735 4d4eceb852d4542f253cdfed31276560 124 SUPERFAMILY SSF56349 4 112 8.01E-24 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS04735 4d4eceb852d4542f253cdfed31276560 124 Pfam PF00589 Phage integrase family 11 108 5.6E-18 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS12200 99eb751b18e6a167a093ffabe0045289 393 Pfam PF02655 ATP-grasp domain 116 294 1.2E-6 T 29-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 CB4_RS12200 99eb751b18e6a167a093ffabe0045289 393 Gene3D G3DSA:3.30.470.20 108 359 6.7E-28 T 29-03-2018 CB4_RS12200 99eb751b18e6a167a093ffabe0045289 393 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS12200 99eb751b18e6a167a093ffabe0045289 393 SUPERFAMILY SSF56059 117 312 1.24E-24 T 29-03-2018 CB4_RS16110 2c9f588f4fab7cb362664c34d093fc8c 312 ProDom PD135861 METAL-BINDING IRON CSID GAB CYTOPLASMIC 3D-STRUCTURE HOMOLOG DIRECT SEQUENCING 24 309 7.0E-84 T 29-03-2018 IPR015038 Uncharacterised protein family CsiD GO:0005506 CB4_RS16110 2c9f588f4fab7cb362664c34d093fc8c 312 Pfam PF08943 CsiD 19 309 2.0E-123 T 29-03-2018 IPR015038 Uncharacterised protein family CsiD GO:0005506 CB4_RS16110 2c9f588f4fab7cb362664c34d093fc8c 312 Gene3D G3DSA:3.60.130.10 13 310 4.3E-45 T 29-03-2018 CB4_RS16110 2c9f588f4fab7cb362664c34d093fc8c 312 SUPERFAMILY SSF51197 14 310 4.17E-75 T 29-03-2018 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 Gene3D G3DSA:1.10.287.130 300 373 1.5E-20 T 29-03-2018 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 SUPERFAMILY SSF55874 366 538 1.15E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 Pfam PF00672 HAMP domain 235 282 6.5E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 Gene3D G3DSA:3.30.565.10 381 544 4.6E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 Pfam PF00512 His Kinase A (phospho-acceptor) domain 309 377 8.5E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 SUPERFAMILY SSF47384 295 378 4.51E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 PRINTS PR00344 Bacterial sensor protein C-terminal signature 495 513 8.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 532 8.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 474 8.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 488 8.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 SUPERFAMILY SSF158472 235 286 7.45E-10 T 29-03-2018 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 SMART SM00388 309 377 1.6E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 SMART SM00304 235 287 1.2E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 424 533 6.9E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16665 80692a9ca35168b1aac9378b57a9db93 668 SMART SM00387 423 535 8.5E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS04155 4dc71fe661914f8ca6e8851ba71761c2 501 Pfam PF15975 Flotillin 367 445 4.0E-11 T 29-03-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 CB4_RS04155 4dc71fe661914f8ca6e8851ba71761c2 501 Pfam PF01145 SPFH domain / Band 7 family 47 217 3.5E-25 T 29-03-2018 IPR001107 Band 7 domain CB4_RS04155 4dc71fe661914f8ca6e8851ba71761c2 501 SMART SM00244 24 202 9.3E-4 T 29-03-2018 IPR001107 Band 7 domain CB4_RS04155 4dc71fe661914f8ca6e8851ba71761c2 501 SUPERFAMILY SSF117892 67 209 2.75E-34 T 29-03-2018 IPR001107 Band 7 domain CB4_RS16465 31e3276dc9e3130b6e4dc9a621cb0224 453 Pfam PF00571 CBS domain 292 341 6.8E-7 T 29-03-2018 IPR000644 CBS domain CB4_RS16465 31e3276dc9e3130b6e4dc9a621cb0224 453 Pfam PF00571 CBS domain 223 278 7.2E-4 T 29-03-2018 IPR000644 CBS domain CB4_RS16465 31e3276dc9e3130b6e4dc9a621cb0224 453 Gene3D G3DSA:3.30.465.10 352 449 1.9E-24 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CB4_RS16465 31e3276dc9e3130b6e4dc9a621cb0224 453 Pfam PF01595 Domain of unknown function DUF21 14 207 3.7E-52 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CB4_RS16465 31e3276dc9e3130b6e4dc9a621cb0224 453 SMART SM01091 356 434 7.5E-23 T 29-03-2018 IPR005170 Transporter-associated domain CB4_RS16465 31e3276dc9e3130b6e4dc9a621cb0224 453 SUPERFAMILY SSF56176 354 443 1.74E-22 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CB4_RS16465 31e3276dc9e3130b6e4dc9a621cb0224 453 Gene3D G3DSA:3.10.580.10 202 351 1.5E-31 T 29-03-2018 CB4_RS16465 31e3276dc9e3130b6e4dc9a621cb0224 453 SUPERFAMILY SSF54631 217 357 2.91E-30 T 29-03-2018 CB4_RS16465 31e3276dc9e3130b6e4dc9a621cb0224 453 Pfam PF03471 Transporter associated domain 357 433 4.9E-19 T 29-03-2018 IPR005170 Transporter-associated domain CB4_RS01245 a2704c9f15708ba8b86598756aac070c 359 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 26 136 1.4E-27 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CB4_RS01245 a2704c9f15708ba8b86598756aac070c 359 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 1 356 45.325 T 29-03-2018 IPR023763 DNA integrity scanning protein, DisA CB4_RS01245 a2704c9f15708ba8b86598756aac070c 359 SUPERFAMILY SSF47781 287 346 2.3E-10 T 29-03-2018 IPR010994 RuvA domain 2-like CB4_RS01245 a2704c9f15708ba8b86598756aac070c 359 SUPERFAMILY SSF143597 17 142 5.62E-31 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CB4_RS01245 a2704c9f15708ba8b86598756aac070c 359 Pfam PF10635 DisA bacterial checkpoint controller linker region 143 279 2.5E-55 T 29-03-2018 IPR018906 DNA integrity scanning, DisA, linker region CB4_RS01245 a2704c9f15708ba8b86598756aac070c 359 Gene3D G3DSA:3.40.1700.10 7 143 1.9E-26 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CB4_RS01245 a2704c9f15708ba8b86598756aac070c 359 Gene3D G3DSA:1.10.150.20 292 356 2.7E-8 T 29-03-2018 CB4_RS16740 8ce12bd6c3a47ef28ace67b0d5c3e107 259 SUPERFAMILY SSF52266 56 258 2.4E-36 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CB4_RS16740 8ce12bd6c3a47ef28ace67b0d5c3e107 259 Gene3D G3DSA:3.40.50.1110 53 259 6.2E-38 T 29-03-2018 CB4_RS16740 8ce12bd6c3a47ef28ace67b0d5c3e107 259 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 62 249 2.7E-27 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CB4_RS15030 7b7ec2c38163e6cac55d98667faffe1a 193 SUPERFAMILY SSF52317 2 185 4.42E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS15030 7b7ec2c38163e6cac55d98667faffe1a 193 Pfam PF01965 DJ-1/PfpI family 2 166 5.2E-19 T 29-03-2018 IPR002818 DJ-1/PfpI CB4_RS15030 7b7ec2c38163e6cac55d98667faffe1a 193 Gene3D G3DSA:3.40.50.880 1 190 4.5E-37 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS05340 a2c500675759e6b13e0ecba21469a24f 624 Pfam PF07728 AAA domain (dynein-related subfamily) 390 481 4.4E-9 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CB4_RS05340 a2c500675759e6b13e0ecba21469a24f 624 Gene3D G3DSA:3.40.50.300 71 488 1.6E-24 T 29-03-2018 CB4_RS05340 a2c500675759e6b13e0ecba21469a24f 624 SUPERFAMILY SSF52540 124 169 2.75E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05340 a2c500675759e6b13e0ecba21469a24f 624 SUPERFAMILY SSF52540 381 490 2.75E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19115 bdb625c75d43f088cdf0ada4410ee48e 157 Gene3D G3DSA:3.40.30.10 1 154 6.5E-42 T 29-03-2018 CB4_RS19115 bdb625c75d43f088cdf0ada4410ee48e 157 SUPERFAMILY SSF52833 5 153 2.28E-53 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS19115 bdb625c75d43f088cdf0ada4410ee48e 157 PIRSF PIRSF000239 1 143 1.4E-29 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS19115 bdb625c75d43f088cdf0ada4410ee48e 157 Pfam PF00578 AhpC/TSA family 6 133 6.0E-42 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS05685 c5b637c38ae24ef516ed87f89b6a1f7f 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 9 428 3.5E-191 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CB4_RS05685 c5b637c38ae24ef516ed87f89b6a1f7f 429 SUPERFAMILY SSF53383 5 429 3.78E-134 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS05685 c5b637c38ae24ef516ed87f89b6a1f7f 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 274 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS05685 c5b637c38ae24ef516ed87f89b6a1f7f 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 7 429 104.904 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CB4_RS05685 c5b637c38ae24ef516ed87f89b6a1f7f 429 Gene3D G3DSA:3.40.640.10 174 308 3.6E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS05685 c5b637c38ae24ef516ed87f89b6a1f7f 429 Gene3D G3DSA:3.90.1150.10 2 173 4.3E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS05685 c5b637c38ae24ef516ed87f89b6a1f7f 429 Pfam PF00202 Aminotransferase class-III 36 393 2.8E-76 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS05685 c5b637c38ae24ef516ed87f89b6a1f7f 429 Gene3D G3DSA:3.90.1150.10 309 429 2.7E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS01225 d758e5b8af062e05cd18c0cadb6f4524 227 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 1 219 42.912 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CB4_RS01225 d758e5b8af062e05cd18c0cadb6f4524 227 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 219 5.7E-79 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CB4_RS01225 d758e5b8af062e05cd18c0cadb6f4524 227 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 221 1.6E-75 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CB4_RS01225 d758e5b8af062e05cd18c0cadb6f4524 227 SUPERFAMILY SSF53448 2 220 5.85E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS01225 d758e5b8af062e05cd18c0cadb6f4524 227 Gene3D G3DSA:3.90.550.10 1 227 2.5E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS01225 d758e5b8af062e05cd18c0cadb6f4524 227 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 96 103 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CB4_RS17330 123488f99adec97df26a8a2e7b7a10ea 364 Gene3D G3DSA:3.20.20.70 98 354 3.5E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS17330 123488f99adec97df26a8a2e7b7a10ea 364 Pfam PF00793 DAHP synthetase I family 112 349 9.8E-82 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CB4_RS17330 123488f99adec97df26a8a2e7b7a10ea 364 Pfam PF01817 Chorismate mutase type II 10 87 2.1E-18 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CB4_RS17330 123488f99adec97df26a8a2e7b7a10ea 364 SMART SM00830 10 89 9.8E-24 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CB4_RS17330 123488f99adec97df26a8a2e7b7a10ea 364 SUPERFAMILY SSF51569 44 352 3.85E-103 T 29-03-2018 CB4_RS17330 123488f99adec97df26a8a2e7b7a10ea 364 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 6.6E-121 T 29-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CB4_RS17330 123488f99adec97df26a8a2e7b7a10ea 364 Gene3D G3DSA:1.20.59.10 1 97 6.4E-25 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CB4_RS17330 123488f99adec97df26a8a2e7b7a10ea 364 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 101 2.5E-41 T 29-03-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CB4_RS07450 89d80adaa3547fa687d59d6b5f1a3023 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 462 540 3.1E-25 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS07450 89d80adaa3547fa687d59d6b5f1a3023 563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS07450 89d80adaa3547fa687d59d6b5f1a3023 563 Gene3D G3DSA:3.40.50.980 209 360 2.5E-40 T 29-03-2018 CB4_RS07450 89d80adaa3547fa687d59d6b5f1a3023 563 SUPERFAMILY SSF56801 15 553 1.44E-161 T 29-03-2018 CB4_RS07450 89d80adaa3547fa687d59d6b5f1a3023 563 Pfam PF00501 AMP-binding enzyme 49 453 1.6E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS07450 89d80adaa3547fa687d59d6b5f1a3023 563 Gene3D G3DSA:3.40.50.980 34 208 1.1E-40 T 29-03-2018 CB4_RS07450 89d80adaa3547fa687d59d6b5f1a3023 563 Gene3D G3DSA:3.30.300.30 449 561 6.1E-29 T 29-03-2018 CB4_RS07450 89d80adaa3547fa687d59d6b5f1a3023 563 Gene3D G3DSA:2.30.38.10 361 446 1.2E-20 T 29-03-2018 CB4_RS05230 df8af7f086c26f1cd3ff600ebf0f007b 136 PRINTS PR01438 Universal stress protein signature 96 108 1.1E-7 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS05230 df8af7f086c26f1cd3ff600ebf0f007b 136 PRINTS PR01438 Universal stress protein signature 114 136 1.1E-7 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS05230 df8af7f086c26f1cd3ff600ebf0f007b 136 Pfam PF00582 Universal stress protein family 2 136 1.1E-15 T 29-03-2018 IPR006016 UspA GO:0006950 CB4_RS05230 df8af7f086c26f1cd3ff600ebf0f007b 136 Gene3D G3DSA:3.40.50.620 1 136 9.6E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS05230 df8af7f086c26f1cd3ff600ebf0f007b 136 SUPERFAMILY SSF52402 1 136 7.2E-22 T 29-03-2018 CB4_RS01730 824cad004ce41456bd8da5e993629f98 254 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CB4_RS01730 824cad004ce41456bd8da5e993629f98 254 Gene3D G3DSA:1.10.12.10 215 252 7.3E-18 T 29-03-2018 IPR014748 Crontonase, C-terminal CB4_RS01730 824cad004ce41456bd8da5e993629f98 254 Gene3D G3DSA:3.90.226.10 1 214 1.1E-70 T 29-03-2018 CB4_RS01730 824cad004ce41456bd8da5e993629f98 254 SUPERFAMILY SSF52096 4 253 3.81E-79 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS01730 824cad004ce41456bd8da5e993629f98 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 253 8.9E-59 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CB4_RS08680 d5374f1c5a584c7f9df60b283d3f7cf3 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 168 5.6E-51 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CB4_RS08680 d5374f1c5a584c7f9df60b283d3f7cf3 171 Gene3D G3DSA:2.40.30.60 2 95 4.9E-25 T 29-03-2018 IPR002676 RimM protein GO:0006364 CB4_RS08680 d5374f1c5a584c7f9df60b283d3f7cf3 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 170 24.239 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CB4_RS08680 d5374f1c5a584c7f9df60b283d3f7cf3 171 Pfam PF05239 PRC-barrel domain 98 164 3.0E-12 T 29-03-2018 IPR027275 PRC-barrel domain CB4_RS08680 d5374f1c5a584c7f9df60b283d3f7cf3 171 Gene3D G3DSA:2.30.30.240 96 165 3.8E-21 T 29-03-2018 CB4_RS08680 d5374f1c5a584c7f9df60b283d3f7cf3 171 SUPERFAMILY SSF50447 3 91 1.8E-20 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CB4_RS08680 d5374f1c5a584c7f9df60b283d3f7cf3 171 SUPERFAMILY SSF50346 100 170 2.67E-19 T 29-03-2018 IPR011033 PRC-barrel-like CB4_RS08680 d5374f1c5a584c7f9df60b283d3f7cf3 171 Pfam PF01782 RimM N-terminal domain 7 90 7.0E-23 T 29-03-2018 IPR002676 RimM protein GO:0006364 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 832 839 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Gene3D G3DSA:1.10.1030.10 403 533 1.1E-51 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Gene3D G3DSA:3.30.470.20 120 401 8.7E-68 T 29-03-2018 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Gene3D G3DSA:3.40.50.1380 923 1051 1.6E-34 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS08395 ca243036de0981f569729a60d5038047 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 9.7E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 9.7E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 9.7E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 9.7E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 9.7E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 9.7E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 9.7E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 SMART SM01096 420 542 1.6E-67 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Pfam PF02142 MGS-like domain 952 1038 3.7E-16 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1059 13.204 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 668 869 2.3E-35 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 5.7E-83 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Gene3D G3DSA:3.40.50.20 4 117 2.5E-37 T 29-03-2018 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Gene3D G3DSA:3.40.50.20 534 649 1.6E-62 T 29-03-2018 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Gene3D G3DSA:3.30.1490.20 650 739 2.8E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 SUPERFAMILY SSF52440 1 127 3.45E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS08395 ca243036de0981f569729a60d5038047 1067 SUPERFAMILY SSF48108 395 548 4.97E-49 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 SUPERFAMILY SSF52440 551 670 1.06E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS08395 ca243036de0981f569729a60d5038047 1067 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 542 2.6E-42 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 SMART SM00851 951 1038 1.4E-22 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS08395 ca243036de0981f569729a60d5038047 1067 SUPERFAMILY SSF56059 668 929 5.3E-101 T 29-03-2018 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 SUPERFAMILY SSF52335 931 1053 1.96E-30 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CB4_RS08395 ca243036de0981f569729a60d5038047 1067 SUPERFAMILY SSF56059 128 399 6.54E-109 T 29-03-2018 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1066 13.606 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 Gene3D G3DSA:3.30.470.20 740 922 9.4E-37 T 29-03-2018 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 704 718 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CB4_RS08395 ca243036de0981f569729a60d5038047 1067 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 4 1049 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Gene3D G3DSA:3.40.50.720 1519 1769 1.2E-9 T 29-03-2018 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 SUPERFAMILY SSF51735 1359 1515 1.16E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Pfam PF00107 Zinc-binding dehydrogenase 1395 1516 1.1E-11 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Gene3D G3DSA:3.40.50.720 1378 1518 1.1E-17 T 29-03-2018 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 SMART SM00829 1221 1573 9.1E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 951 971 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Gene3D G3DSA:3.90.226.10 851 1162 7.7E-62 T 29-03-2018 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Gene3D G3DSA:3.40.50.980 103 420 1.4E-34 T 29-03-2018 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 81 109 4.8E-7 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Gene3D G3DSA:3.30.300.30 695 810 7.8E-16 T 29-03-2018 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Pfam PF00501 AMP-binding enzyme 149 701 1.7E-48 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 SUPERFAMILY SSF52096 860 1146 1.29E-53 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 SUPERFAMILY SSF50129 1229 1386 7.63E-16 T 29-03-2018 IPR011032 GroES-like CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Pfam PF13193 AMP-binding enzyme C-terminal domain 726 794 9.5E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 ProSitePatterns PS00455 Putative AMP-binding domain signature. 415 426 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Gene3D G3DSA:3.90.180.10 1216 1377 5.6E-15 T 29-03-2018 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Gene3D G3DSA:3.40.50.980 421 588 7.5E-26 T 29-03-2018 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 SUPERFAMILY SSF56801 379 825 1.72E-95 T 29-03-2018 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 SUPERFAMILY SSF56801 83 262 1.72E-95 T 29-03-2018 CB4_RS18955 194dd3f035fc87ec05fc744336baf80b 1804 Pfam PF00378 Enoyl-CoA hydratase/isomerase 861 1071 2.4E-39 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CB4_RS01690 72285018e09bbfdc69651adb42e44d28 424 Gene3D G3DSA:1.20.1600.10 159 224 3.9E-7 T 29-03-2018 CB4_RS01690 72285018e09bbfdc69651adb42e44d28 424 Gene3D G3DSA:2.40.50.100 47 121 9.4E-18 T 29-03-2018 CB4_RS01690 72285018e09bbfdc69651adb42e44d28 424 SUPERFAMILY SSF111369 49 149 2.48E-9 T 29-03-2018 CB4_RS01690 72285018e09bbfdc69651adb42e44d28 424 Gene3D G3DSA:1.20.1600.10 227 348 2.7E-14 T 29-03-2018 CB4_RS01690 72285018e09bbfdc69651adb42e44d28 424 Pfam PF13533 Biotin-lipoyl like 50 96 6.8E-15 T 29-03-2018 CB4_RS01690 72285018e09bbfdc69651adb42e44d28 424 SUPERFAMILY SSF111369 223 353 2.35E-11 T 29-03-2018 CB4_RS01690 72285018e09bbfdc69651adb42e44d28 424 Pfam PF13437 HlyD family secretion protein 302 379 9.3E-10 T 29-03-2018 CB4_RS01585 6b612189e886a49d031f97a18487dd0d 141 Gene3D G3DSA:1.20.120.490 23 140 9.1E-38 T 29-03-2018 IPR024042 Hypothetical protein TM1646-like domain CB4_RS01585 6b612189e886a49d031f97a18487dd0d 141 SUPERFAMILY SSF158397 23 140 8.37E-34 T 29-03-2018 CB4_RS01585 6b612189e886a49d031f97a18487dd0d 141 Pfam PF03885 Protein of unknown function (DUF327) 15 140 6.9E-40 T 29-03-2018 IPR005585 Protein of unknown function DUF327 CB4_RS16605 feb9f8c6711ca79d25840534f2d7e009 288 Pfam PF10728 Domain of unknown function (DUF2520) 136 262 2.0E-35 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 CB4_RS16605 feb9f8c6711ca79d25840534f2d7e009 288 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 3 31 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CB4_RS16605 feb9f8c6711ca79d25840534f2d7e009 288 Pfam PF10727 Rossmann-like domain 2 118 1.3E-18 T 29-03-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain CB4_RS16605 feb9f8c6711ca79d25840534f2d7e009 288 SUPERFAMILY SSF51735 2 164 5.01E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS16605 feb9f8c6711ca79d25840534f2d7e009 288 Gene3D G3DSA:3.40.50.720 1 166 1.0E-21 T 29-03-2018 CB4_RS16605 feb9f8c6711ca79d25840534f2d7e009 288 Gene3D G3DSA:1.10.1040.20 168 268 1.5E-27 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 CB4_RS16605 feb9f8c6711ca79d25840534f2d7e009 288 SUPERFAMILY SSF48179 168 269 1.63E-24 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS04260 47b68aa96419f8aefe911a290ba68ad0 215 SUPERFAMILY SSF75615 115 207 3.4E-15 T 29-03-2018 CB4_RS04260 47b68aa96419f8aefe911a290ba68ad0 215 Gene3D G3DSA:3.40.50.720 3 106 1.0E-13 T 29-03-2018 CB4_RS04260 47b68aa96419f8aefe911a290ba68ad0 215 SUPERFAMILY SSF51735 5 113 1.97E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS04260 47b68aa96419f8aefe911a290ba68ad0 215 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 7 189 6.5E-34 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CB4_RS04260 47b68aa96419f8aefe911a290ba68ad0 215 Gene3D G3DSA:3.30.160.110 107 148 2.0E-16 T 29-03-2018 CB4_RS04260 47b68aa96419f8aefe911a290ba68ad0 215 Pfam PF13241 Putative NAD(P)-binding 10 116 2.2E-26 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CB4_RS06775 be67b0d73c8523584a0b997fa817422c 275 SMART SM00332 23 267 1.0E-5 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS06775 be67b0d73c8523584a0b997fa817422c 275 SMART SM00331 33 269 1.0E-4 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS06775 be67b0d73c8523584a0b997fa817422c 275 Gene3D G3DSA:3.60.40.10 22 268 8.7E-25 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS06775 be67b0d73c8523584a0b997fa817422c 275 Pfam PF13672 Protein phosphatase 2C 38 226 1.4E-12 T 29-03-2018 CB4_RS06775 be67b0d73c8523584a0b997fa817422c 275 SUPERFAMILY SSF81606 30 267 4.32E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS15100 9a2d1cf7043ad741ee2dbbfe5fbcef86 274 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 52 65 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS15100 9a2d1cf7043ad741ee2dbbfe5fbcef86 274 SUPERFAMILY SSF51366 11 245 3.3E-78 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CB4_RS15100 9a2d1cf7043ad741ee2dbbfe5fbcef86 274 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 19 270 1.1E-80 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS15100 9a2d1cf7043ad741ee2dbbfe5fbcef86 274 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 273 34.855 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS15100 9a2d1cf7043ad741ee2dbbfe5fbcef86 274 Pfam PF00290 Tryptophan synthase alpha chain 17 257 1.4E-86 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CB4_RS15100 9a2d1cf7043ad741ee2dbbfe5fbcef86 274 Gene3D G3DSA:3.20.20.70 9 274 1.0E-74 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS05700 3463adf53787f0c827421f2b2e3804c8 388 Gene3D G3DSA:3.30.200.20 44 147 5.4E-9 T 29-03-2018 CB4_RS05700 3463adf53787f0c827421f2b2e3804c8 388 SUPERFAMILY SSF56112 58 342 7.35E-26 T 29-03-2018 IPR011009 Protein kinase-like domain CB4_RS05700 3463adf53787f0c827421f2b2e3804c8 388 Pfam PF01636 Phosphotransferase enzyme family 78 323 1.5E-10 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CB4_RS05700 3463adf53787f0c827421f2b2e3804c8 388 Gene3D G3DSA:3.90.1200.10 157 386 3.2E-15 T 29-03-2018 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 565 41.749 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 Gene3D G3DSA:3.40.50.800 457 569 1.1E-30 T 29-03-2018 IPR004154 Anticodon-binding CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 560 9.4E-234 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 SUPERFAMILY SSF55826 218 386 3.66E-30 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 Pfam PF04073 Aminoacyl-tRNA editing domain 257 375 1.2E-26 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 Gene3D G3DSA:3.30.930.10 11 456 1.9E-103 T 29-03-2018 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 SUPERFAMILY SSF52954 459 566 1.8E-29 T 29-03-2018 IPR004154 Anticodon-binding CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 PIRSF PIRSF001535 1 567 1.7E-268 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 SUPERFAMILY SSF55681 9 237 2.19E-102 T 29-03-2018 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 SUPERFAMILY SSF55681 403 474 2.19E-102 T 29-03-2018 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.7E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.7E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.7E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.7E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 455 6.1E-50 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS09300 5341c1930b17634836cb79fbe2cb3f28 569 Pfam PF03129 Anticodon binding domain 471 561 1.4E-19 T 29-03-2018 IPR004154 Anticodon-binding CB4_RS05155 966a7c1783dd707eba657e9deb0429bf 407 SUPERFAMILY SSF103473 6 387 2.35E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS05155 966a7c1783dd707eba657e9deb0429bf 407 Gene3D G3DSA:1.20.1250.20 6 196 1.6E-34 T 29-03-2018 CB4_RS05155 966a7c1783dd707eba657e9deb0429bf 407 Pfam PF07690 Major Facilitator Superfamily 17 352 2.2E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS05155 966a7c1783dd707eba657e9deb0429bf 407 Gene3D G3DSA:1.20.1250.20 199 397 7.1E-17 T 29-03-2018 CB4_RS02205 e859e0e2e3c111dd29bf03efdccf603d 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 19.654 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CB4_RS02205 e859e0e2e3c111dd29bf03efdccf603d 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 2.2E-26 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CB4_RS02205 e859e0e2e3c111dd29bf03efdccf603d 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 3.5E-26 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CB4_RS02205 e859e0e2e3c111dd29bf03efdccf603d 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 6.0E-17 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CB4_RS12865 07834ab7084c5d2a13200c389e2d0638 277 Pfam PF00303 Thymidylate synthase 8 277 1.3E-85 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CB4_RS12865 07834ab7084c5d2a13200c389e2d0638 277 Hamap MF_00008 Thymidylate synthase [thyA]. 5 277 35.267 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CB4_RS12865 07834ab7084c5d2a13200c389e2d0638 277 SUPERFAMILY SSF55831 5 277 1.96E-91 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CB4_RS12865 07834ab7084c5d2a13200c389e2d0638 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 98 277 2.8E-46 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CB4_RS12865 07834ab7084c5d2a13200c389e2d0638 277 Gene3D G3DSA:3.30.572.10 5 277 1.3E-92 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CB4_RS12865 07834ab7084c5d2a13200c389e2d0638 277 PRINTS PR00108 Thymidylate synthase family signature 210 227 1.4E-28 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CB4_RS12865 07834ab7084c5d2a13200c389e2d0638 277 PRINTS PR00108 Thymidylate synthase family signature 172 198 1.4E-28 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CB4_RS12865 07834ab7084c5d2a13200c389e2d0638 277 PRINTS PR00108 Thymidylate synthase family signature 54 75 1.4E-28 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CB4_RS12865 07834ab7084c5d2a13200c389e2d0638 277 PRINTS PR00108 Thymidylate synthase family signature 154 169 1.4E-28 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CB4_RS12865 07834ab7084c5d2a13200c389e2d0638 277 PRINTS PR00108 Thymidylate synthase family signature 128 147 1.4E-28 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CB4_RS12540 2dc0377968d9a2ba7faaffd51912078a 397 Gene3D G3DSA:3.40.640.10 43 293 4.2E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS12540 2dc0377968d9a2ba7faaffd51912078a 397 Gene3D G3DSA:3.90.1150.10 294 392 6.8E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS12540 2dc0377968d9a2ba7faaffd51912078a 397 Pfam PF00155 Aminotransferase class I and II 39 370 7.5E-41 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS12540 2dc0377968d9a2ba7faaffd51912078a 397 SUPERFAMILY SSF53383 2 391 1.33E-102 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS08280 0f7ebfea19108b485a06e155a23bbc96 244 Pfam PF05949 Bacterial protein of unknown function (DUF881) 88 236 7.7E-33 T 29-03-2018 IPR010273 Protein of unknown function DUF881 CB4_RS11785 1f975dfca97d5249dd05d469c148a4a3 70 Pfam PF01381 Helix-turn-helix 10 64 1.9E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS11785 1f975dfca97d5249dd05d469c148a4a3 70 SUPERFAMILY SSF47413 9 68 5.35E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS11785 1f975dfca97d5249dd05d469c148a4a3 70 Gene3D G3DSA:1.10.260.40 8 70 1.1E-17 T 29-03-2018 CB4_RS11785 1f975dfca97d5249dd05d469c148a4a3 70 SMART SM00530 9 64 3.2E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 SUPERFAMILY SSF55681 117 299 1.91E-109 T 29-03-2018 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 SUPERFAMILY SSF55681 427 586 1.91E-109 T 29-03-2018 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 586 5.2E-253 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 SUPERFAMILY SSF55261 296 422 3.92E-45 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 5 587 34.774 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 Pfam PF02938 GAD domain 315 408 4.0E-30 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 Pfam PF01336 OB-fold nucleic acid binding domain 22 107 1.5E-17 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 1.7E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 214 227 1.7E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 1.7E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 209 1.7E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 Gene3D G3DSA:2.40.50.140 1 113 1.2E-28 T 29-03-2018 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 Pfam PF00152 tRNA synthetases class II (D, K and N) 124 560 5.0E-111 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 SUPERFAMILY SSF50249 6 110 4.57E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS06035 a1d9d8a5cddcba5cc79cb99ec6933a36 594 Gene3D G3DSA:3.30.930.10 138 589 3.5E-112 T 29-03-2018 CB4_RS18620 e83add1ac0460a3ac233c2b2b58b21e6 615 SMART SM00044 387 585 5.7E-35 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CB4_RS18620 e83add1ac0460a3ac233c2b2b58b21e6 615 SMART SM01080 35 330 3.9E-48 T 29-03-2018 IPR007890 CHASE2 CB4_RS18620 e83add1ac0460a3ac233c2b2b58b21e6 615 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 424 600 2.1E-40 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CB4_RS18620 e83add1ac0460a3ac233c2b2b58b21e6 615 SUPERFAMILY SSF55073 419 606 9.1E-66 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS18620 e83add1ac0460a3ac233c2b2b58b21e6 615 Gene3D G3DSA:3.30.70.1230 417 611 4.4E-57 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CB4_RS18620 e83add1ac0460a3ac233c2b2b58b21e6 615 Pfam PF05226 CHASE2 domain 31 322 4.4E-51 T 29-03-2018 IPR007890 CHASE2 CB4_RS20380 fef9ff02d72fd9949bb60d0e3de912ce 82 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 79 4.5E-34 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS20380 fef9ff02d72fd9949bb60d0e3de912ce 82 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 23.203 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS20380 fef9ff02d72fd9949bb60d0e3de912ce 82 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 1.5E-34 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS20380 fef9ff02d72fd9949bb60d0e3de912ce 82 SUPERFAMILY SSF82697 2 79 1.74E-30 T 29-03-2018 CB4_RS20380 fef9ff02d72fd9949bb60d0e3de912ce 82 Gene3D G3DSA:3.30.1280.10 1 80 5.3E-33 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS20380 fef9ff02d72fd9949bb60d0e3de912ce 82 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 81 2.0E-21 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CB4_RS01435 28fa9e87b86d240a97e93f30f4b6a5c9 192 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 9.1E-21 T 29-03-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like CB4_RS01435 28fa9e87b86d240a97e93f30f4b6a5c9 192 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 3 128 4.5E-28 T 29-03-2018 IPR014242 Spore cortex biosynthesis protein, YabQ CB4_RS00155 f94c6fb434f90c94116b59579827d5f6 223 SMART SM00448 2 112 3.5E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS00155 f94c6fb434f90c94116b59579827d5f6 223 SUPERFAMILY SSF52172 2 126 4.41E-39 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS00155 f94c6fb434f90c94116b59579827d5f6 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 222 3.3E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS00155 f94c6fb434f90c94116b59579827d5f6 223 Gene3D G3DSA:1.10.10.10 125 223 2.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00155 f94c6fb434f90c94116b59579827d5f6 223 Pfam PF00072 Response regulator receiver domain 4 112 5.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS00155 f94c6fb434f90c94116b59579827d5f6 223 Gene3D G3DSA:3.40.50.2300 1 124 2.2E-32 T 29-03-2018 CB4_RS00155 f94c6fb434f90c94116b59579827d5f6 223 SMART SM00862 147 222 3.0E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS00155 f94c6fb434f90c94116b59579827d5f6 223 SUPERFAMILY SSF46894 126 222 3.97E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS05900 5be8acd98c33d48f50e7a71842e45a05 352 TIGRFAM TIGR00260 thrC: threonine synthase 5 322 1.5E-100 T 29-03-2018 IPR004450 Threonine synthase-like CB4_RS05900 5be8acd98c33d48f50e7a71842e45a05 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 49 62 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CB4_RS05900 5be8acd98c33d48f50e7a71842e45a05 352 SUPERFAMILY SSF53686 8 334 2.36E-107 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS05900 5be8acd98c33d48f50e7a71842e45a05 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 22 315 6.2E-79 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS05900 5be8acd98c33d48f50e7a71842e45a05 352 Gene3D G3DSA:3.40.50.1100 143 332 6.2E-54 T 29-03-2018 CB4_RS05900 5be8acd98c33d48f50e7a71842e45a05 352 PIRSF PIRSF038945 1 347 4.3E-163 T 29-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CB4_RS05900 5be8acd98c33d48f50e7a71842e45a05 352 Gene3D G3DSA:3.40.50.1100 36 142 1.9E-28 T 29-03-2018 CB4_RS03170 da8cb081ea5f7c33cacccc891935cae3 230 Gene3D G3DSA:3.90.550.10 1 228 4.5E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS03170 da8cb081ea5f7c33cacccc891935cae3 230 SUPERFAMILY SSF53448 1 225 7.32E-63 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS03170 da8cb081ea5f7c33cacccc891935cae3 230 Pfam PF00483 Nucleotidyl transferase 3 226 1.0E-32 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CB4_RS02500 8adb9e575deef6e804a7fba9171717eb 304 Gene3D G3DSA:3.60.15.10 2 302 1.2E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS02500 8adb9e575deef6e804a7fba9171717eb 304 SUPERFAMILY SSF56281 4 300 6.68E-65 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS02500 8adb9e575deef6e804a7fba9171717eb 304 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 4 298 2.8E-88 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CB4_RS02500 8adb9e575deef6e804a7fba9171717eb 304 Pfam PF12706 Beta-lactamase superfamily domain 32 268 2.0E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS02500 8adb9e575deef6e804a7fba9171717eb 304 Hamap MF_01818 Ribonuclease BN [rbn]. 2 300 30.65 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.6E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.6E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 185 3.7E-5 T 29-03-2018 CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 244 1.0E-72 T 29-03-2018 CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 SUPERFAMILY SSF51735 4 245 4.5E-89 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 Gene3D G3DSA:3.40.50.10090 1 50 5.5E-10 T 29-03-2018 CB4_RS17100 4a7751ebbe2a0db3edbafb88c3d4afd6 246 Gene3D G3DSA:3.40.50.720 51 246 4.7E-75 T 29-03-2018 CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 SMART SM00248 271 300 0.0011 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 SMART SM00248 204 233 3600.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 SMART SM00248 238 267 3.7E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 Pfam PF13637 Ankyrin repeats (many copies) 241 292 1.4E-9 T 29-03-2018 CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 Gene3D G3DSA:3.30.457.10 87 157 3.2E-24 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 Gene3D G3DSA:3.30.457.10 24 86 0.0014 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 SUPERFAMILY SSF48403 204 323 1.41E-28 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 SUPERFAMILY SSF55383 81 163 1.7E-23 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 Gene3D G3DSA:1.25.40.20 207 284 1.7E-21 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 Gene3D G3DSA:1.25.40.20 285 328 1.2E-9 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CB4_RS10385 d915dd1fa08e2f97be5841b42bbe5675 434 Pfam PF07833 Copper amine oxidase N-terminal domain 77 168 6.5E-25 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS12420 9d5c7420e18f21074eb99068394eb309 389 Pfam PF02515 CoA-transferase family III 5 346 1.1E-95 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CB4_RS12420 9d5c7420e18f21074eb99068394eb309 389 Gene3D G3DSA:3.40.50.10540 1 389 8.7E-112 T 29-03-2018 IPR023606 CoA-transferase family III domain CB4_RS12420 9d5c7420e18f21074eb99068394eb309 389 SUPERFAMILY SSF89796 4 389 4.97E-112 T 29-03-2018 IPR023606 CoA-transferase family III domain CB4_RS06935 c819d6e4ed321fce3bd5b8312b3a610a 112 Gene3D G3DSA:1.10.260.40 2 81 3.8E-23 T 29-03-2018 CB4_RS06935 c819d6e4ed321fce3bd5b8312b3a610a 112 SUPERFAMILY SSF47413 4 70 2.49E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS06935 c819d6e4ed321fce3bd5b8312b3a610a 112 SMART SM00530 10 65 3.6E-19 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS06935 c819d6e4ed321fce3bd5b8312b3a610a 112 Pfam PF01381 Helix-turn-helix 11 65 1.2E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS09895 3da6512cd773111574f3902bc543158c 192 SUPERFAMILY SSF46689 7 65 1.65E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS09895 3da6512cd773111574f3902bc543158c 192 Pfam PF16859 Bacterial transcriptional repressor C-terminal 74 183 1.4E-29 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS09895 3da6512cd773111574f3902bc543158c 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS09895 3da6512cd773111574f3902bc543158c 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS09895 3da6512cd773111574f3902bc543158c 192 SUPERFAMILY SSF48498 78 188 4.13E-25 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS09895 3da6512cd773111574f3902bc543158c 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 59 2.3E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS09895 3da6512cd773111574f3902bc543158c 192 Gene3D G3DSA:1.10.357.10 60 187 2.1E-18 T 29-03-2018 CB4_RS09895 3da6512cd773111574f3902bc543158c 192 Gene3D G3DSA:1.10.10.60 1 59 4.0E-15 T 29-03-2018 CB4_RS11680 29ebfcad9b90c1b7624b89e171736f20 154 Pfam PF00436 Single-strand binding protein family 1 100 1.3E-35 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CB4_RS11680 29ebfcad9b90c1b7624b89e171736f20 154 SUPERFAMILY SSF50249 1 154 2.6E-51 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS11680 29ebfcad9b90c1b7624b89e171736f20 154 Hamap MF_00984 Single-stranded DNA-binding protein. 1 105 32.079 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CB4_RS11680 29ebfcad9b90c1b7624b89e171736f20 154 Gene3D G3DSA:2.40.50.140 1 120 7.6E-39 T 29-03-2018 CB4_RS11680 29ebfcad9b90c1b7624b89e171736f20 154 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 154 1.1E-42 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CB4_RS12520 3dbfcdc57fd8ba7cc003c67d32658876 196 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CB4_RS12520 3dbfcdc57fd8ba7cc003c67d32658876 196 SMART SM00072 7 191 5.7E-10 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CB4_RS12520 3dbfcdc57fd8ba7cc003c67d32658876 196 SUPERFAMILY SSF52540 9 184 1.28E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12520 3dbfcdc57fd8ba7cc003c67d32658876 196 Pfam PF00625 Guanylate kinase 9 155 4.2E-18 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CB4_RS12520 3dbfcdc57fd8ba7cc003c67d32658876 196 Gene3D G3DSA:3.40.50.300 2 191 1.1E-30 T 29-03-2018 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 133 144 2.8E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 259 268 2.8E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 2.8E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 2.8E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 153 300 8.9E-31 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 5 302 2.1E-102 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 Gene3D G3DSA:3.40.50.1370 146 307 2.4E-50 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 SUPERFAMILY SSF53671 4 303 4.06E-93 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 Gene3D G3DSA:3.40.50.1370 1 145 1.7E-48 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 3 306 34.907 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 224 233 1.4E-38 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 1.4E-38 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 1.4E-38 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 132 149 1.4E-38 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 78 87 1.4E-38 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 263 268 1.4E-38 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 145 3.0E-45 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CB4_RS10660 07e00b46aa93b723b476ac18edfb7b0e 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CB4_RS10440 937e328c9ffe3316f031ee6563c90d06 606 Gene3D G3DSA:1.10.1370.10 34 600 6.1E-47 T 29-03-2018 CB4_RS10440 937e328c9ffe3316f031ee6563c90d06 606 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 12 600 8.2E-214 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CB4_RS10440 937e328c9ffe3316f031ee6563c90d06 606 SUPERFAMILY SSF55486 7 581 4.19E-133 T 29-03-2018 CB4_RS10440 937e328c9ffe3316f031ee6563c90d06 606 Pfam PF08439 Oligopeptidase F 119 187 5.0E-22 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CB4_RS10440 937e328c9ffe3316f031ee6563c90d06 606 Pfam PF01432 Peptidase family M3 208 587 1.7E-78 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CB4_RS04080 0a512d31f625226ab4bb15402b008341 304 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 13 302 1.8E-39 T 29-03-2018 CB4_RS04080 0a512d31f625226ab4bb15402b008341 304 Gene3D G3DSA:3.40.50.150 108 304 2.2E-29 T 29-03-2018 CB4_RS04080 0a512d31f625226ab4bb15402b008341 304 PIRSF PIRSF000401 1 304 2.4E-45 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CB4_RS04080 0a512d31f625226ab4bb15402b008341 304 SUPERFAMILY SSF53335 63 298 1.96E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS15410 45bea8cf1948893f9a353ac8968d7355 935 Gene3D G3DSA:2.120.10.10 588 707 5.1E-7 T 29-03-2018 CB4_RS15410 45bea8cf1948893f9a353ac8968d7355 935 SUPERFAMILY SSF50939 659 893 2.07E-10 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CB4_RS15410 45bea8cf1948893f9a353ac8968d7355 935 Gene3D G3DSA:2.120.10.10 708 904 5.7E-11 T 29-03-2018 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 SUPERFAMILY SSF51161 1227 1333 1.66E-13 T 29-03-2018 IPR011004 Trimeric LpxA-like CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 SUPERFAMILY SSF56801 29 553 2.49E-158 T 29-03-2018 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Gene3D G3DSA:2.160.10.10 744 881 8.8E-13 T 29-03-2018 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 58 455 3.9E-137 T 29-03-2018 IPR010071 Amino acid adenylation domain CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 1038 1066 4.4E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Pfam PF00550 Phosphopantetheine attachment site 544 609 1.0E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Pfam PF00501 AMP-binding enzyme 37 431 1.8E-104 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Gene3D G3DSA:3.40.50.980 187 338 2.3E-36 T 29-03-2018 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Gene3D G3DSA:3.40.50.980 28 186 8.9E-50 T 29-03-2018 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Gene3D G3DSA:2.160.10.10 1173 1334 5.2E-11 T 29-03-2018 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Gene3D G3DSA:2.160.10.10 975 1105 5.4E-14 T 29-03-2018 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 PRINTS PR00154 AMP-binding signature 176 187 4.0E-5 T 29-03-2018 IPR020459 AMP-binding CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 PRINTS PR00154 AMP-binding signature 188 196 4.0E-5 T 29-03-2018 IPR020459 AMP-binding CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Gene3D G3DSA:2.30.38.10 339 421 1.0E-25 T 29-03-2018 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 SUPERFAMILY SSF51161 982 1095 1.52E-18 T 29-03-2018 IPR011004 Trimeric LpxA-like CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Gene3D G3DSA:1.10.1200.10 546 622 4.0E-16 T 29-03-2018 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 SUPERFAMILY SSF47336 534 609 1.07E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 650 1330 3.1E-178 T 29-03-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Gene3D G3DSA:3.30.300.30 426 545 3.6E-33 T 29-03-2018 CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 SUPERFAMILY SSF51161 703 849 2.08E-15 T 29-03-2018 IPR011004 Trimeric LpxA-like CB4_RS13295 3f2b69479870e4c9299954fd66d1c21e 1334 Pfam PF13193 AMP-binding enzyme C-terminal domain 439 514 1.6E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS19700 413f55e2ace2e8a9c29debe61a71741d 128 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 60 78 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CB4_RS19700 413f55e2ace2e8a9c29debe61a71741d 128 SUPERFAMILY SSF46785 29 116 1.22E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19700 413f55e2ace2e8a9c29debe61a71741d 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 2.6E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS19700 413f55e2ace2e8a9c29debe61a71741d 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 2.6E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS19700 413f55e2ace2e8a9c29debe61a71741d 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 86 101 2.6E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS19700 413f55e2ace2e8a9c29debe61a71741d 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 69 2.6E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS19700 413f55e2ace2e8a9c29debe61a71741d 128 Pfam PF01022 Bacterial regulatory protein, arsR family 44 87 4.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS19700 413f55e2ace2e8a9c29debe61a71741d 128 Gene3D G3DSA:1.10.10.10 1 124 3.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19700 413f55e2ace2e8a9c29debe61a71741d 128 SMART SM00418 36 115 3.0E-24 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS01195 dcaf02af1944dbe626b6c77d3a632faa 248 SMART SM00967 5 80 1.9E-22 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CB4_RS01195 dcaf02af1944dbe626b6c77d3a632faa 248 SUPERFAMILY SSF55315 3 77 2.2E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CB4_RS01195 dcaf02af1944dbe626b6c77d3a632faa 248 Pfam PF00588 SpoU rRNA Methylase family 97 237 1.0E-40 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CB4_RS01195 dcaf02af1944dbe626b6c77d3a632faa 248 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 2 243 2.9E-84 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CB4_RS01195 dcaf02af1944dbe626b6c77d3a632faa 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 79 2.7E-21 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CB4_RS01195 dcaf02af1944dbe626b6c77d3a632faa 248 Gene3D G3DSA:3.40.1280.10 77 247 8.9E-51 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CB4_RS01195 dcaf02af1944dbe626b6c77d3a632faa 248 Gene3D G3DSA:3.30.1330.30 2 76 5.8E-17 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CB4_RS01195 dcaf02af1944dbe626b6c77d3a632faa 248 SUPERFAMILY SSF75217 68 244 9.81E-51 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CB4_RS13205 4488b953188ca52620eb19f6ec17a09e 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 4.6E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13205 4488b953188ca52620eb19f6ec17a09e 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 4.6E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13205 4488b953188ca52620eb19f6ec17a09e 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 4.6E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13205 4488b953188ca52620eb19f6ec17a09e 119 SUPERFAMILY SSF46785 12 99 7.35E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13205 4488b953188ca52620eb19f6ec17a09e 119 Gene3D G3DSA:1.10.10.10 2 100 1.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13205 4488b953188ca52620eb19f6ec17a09e 119 SMART SM00418 13 91 2.5E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13205 4488b953188ca52620eb19f6ec17a09e 119 Pfam PF01022 Bacterial regulatory protein, arsR family 20 64 7.9E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 Gene3D G3DSA:2.60.120.40 559 690 2.0E-23 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 Gene3D G3DSA:2.60.120.40 692 824 5.9E-23 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 Gene3D G3DSA:2.60.120.40 410 557 1.5E-21 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 SUPERFAMILY SSF81296 333 414 3.6E-14 T 29-03-2018 IPR014756 Immunoglobulin E-set CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 Pfam PF00395 S-layer homology domain 89 132 6.2E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 Pfam PF00395 S-layer homology domain 28 70 1.1E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 Pfam PF00395 S-layer homology domain 151 193 1.1E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 Pfam PF01833 IPT/TIG domain 250 330 5.0E-16 T 29-03-2018 IPR002909 IPT domain CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 Pfam PF01833 IPT/TIG domain 334 414 1.2E-10 T 29-03-2018 IPR002909 IPT domain CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 Gene3D G3DSA:2.60.40.10 248 330 2.2E-20 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 Gene3D G3DSA:2.60.40.10 332 409 3.9E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 SMART SM00429 249 331 9.4E-6 T 29-03-2018 IPR002909 IPT domain CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 SMART SM00429 333 415 0.0065 T 29-03-2018 IPR002909 IPT domain CB4_RS15675 a4aa9feb513b344ee99be4490f64679a 828 SUPERFAMILY SSF81296 249 331 6.4E-18 T 29-03-2018 IPR014756 Immunoglobulin E-set CB4_RS07775 fcc3316f48d25145dfc3fbc0f71db569 273 Gene3D G3DSA:3.40.190.10 8 77 1.1E-7 T 29-03-2018 CB4_RS07775 fcc3316f48d25145dfc3fbc0f71db569 273 SUPERFAMILY SSF53850 11 65 5.32E-8 T 29-03-2018 CB4_RS07775 fcc3316f48d25145dfc3fbc0f71db569 273 Gene3D G3DSA:3.30.450.20 106 209 9.5E-5 T 29-03-2018 CB4_RS07775 fcc3316f48d25145dfc3fbc0f71db569 273 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 17 64 3.4E-7 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CB4_RS10190 d4efb784156270096f55c7345e28d7fb 308 SUPERFAMILY SSF52540 2 222 1.33E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10190 d4efb784156270096f55c7345e28d7fb 308 Gene3D G3DSA:3.40.50.300 1 255 2.5E-63 T 29-03-2018 CB4_RS10190 d4efb784156270096f55c7345e28d7fb 308 Pfam PF00005 ABC transporter 17 160 6.1E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS10190 d4efb784156270096f55c7345e28d7fb 308 SMART SM00382 26 238 2.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS17975 b000024b203930f61c9a11ba1024b99f 329 Gene3D G3DSA:3.40.50.720 136 312 4.6E-22 T 29-03-2018 CB4_RS17975 b000024b203930f61c9a11ba1024b99f 329 SUPERFAMILY SSF50129 6 147 1.28E-31 T 29-03-2018 IPR011032 GroES-like CB4_RS17975 b000024b203930f61c9a11ba1024b99f 329 SMART SM00829 12 327 7.8E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CB4_RS17975 b000024b203930f61c9a11ba1024b99f 329 Pfam PF00107 Zinc-binding dehydrogenase 155 268 1.4E-15 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CB4_RS17975 b000024b203930f61c9a11ba1024b99f 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 89 5.8E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CB4_RS17975 b000024b203930f61c9a11ba1024b99f 329 SUPERFAMILY SSF51735 116 292 3.84E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS17975 b000024b203930f61c9a11ba1024b99f 329 Gene3D G3DSA:3.90.180.10 1 135 1.1E-29 T 29-03-2018 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 SUPERFAMILY SSF55973 248 396 1.57E-71 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 Gene3D G3DSA:3.30.300.10 148 248 2.2E-48 T 29-03-2018 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 274 282 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 Gene3D G3DSA:3.30.300.10 15 147 1.7E-45 T 29-03-2018 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 6 398 59.735 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 Gene3D G3DSA:3.30.300.10 261 400 1.2E-49 T 29-03-2018 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 SUPERFAMILY SSF55973 7 113 5.49E-48 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 248 386 3.2E-71 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 8 105 2.8E-44 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 Pfam PF02772 S-adenosylmethionine synthetase, central domain 130 246 8.5E-50 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 SUPERFAMILY SSF55973 125 247 5.1E-53 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 9 396 2.2E-188 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 131 141 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS03345 d9ff1d71c3715c79bcaada5e8bba3b04 404 PIRSF PIRSF000497 2 399 2.8E-178 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CB4_RS09590 8e0498d340df0b4dafc375a4677a6d11 283 Gene3D G3DSA:3.40.50.1820 3 281 5.8E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS09590 8e0498d340df0b4dafc375a4677a6d11 283 SUPERFAMILY SSF53474 7 279 1.92E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS09590 8e0498d340df0b4dafc375a4677a6d11 283 Pfam PF00561 alpha/beta hydrolase fold 29 134 1.7E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 10 741 4.0E-252 T 29-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 471 5.9E-144 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 Gene3D G3DSA:3.90.199.10 34 214 1.5E-78 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 SMART SM00434 11 464 2.4E-228 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 SUPERFAMILY SSF56719 31 486 1.57E-159 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 Gene3D G3DSA:1.10.268.10 344 486 3.9E-44 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 Gene3D G3DSA:3.30.1360.40 236 332 6.8E-29 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 Gene3D G3DSA:2.120.10.90 500 827 1.8E-76 T 29-03-2018 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 SUPERFAMILY SSF101904 500 822 5.36E-72 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 618 655 3.6E-5 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 553 601 1.7E-4 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 705 2.3E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 715 743 2.6E-4 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS10650 c442417587f6ff5592e92b5133c495a7 827 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 505 548 0.66 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 Gene3D G3DSA:1.10.287.470 177 242 2.0E-7 T 29-03-2018 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 Gene3D G3DSA:2.40.50.100 306 475 0.27 T 29-03-2018 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 Gene3D G3DSA:2.40.50.100 243 305 4.9E-5 T 29-03-2018 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 254 474 2.5E-43 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 SUPERFAMILY SSF111369 268 397 8.63E-17 T 29-03-2018 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 SUPERFAMILY SSF111369 227 238 8.63E-17 T 29-03-2018 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 Pfam PF13533 Biotin-lipoyl like 107 154 3.0E-16 T 29-03-2018 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 SUPERFAMILY SSF111369 97 187 3.4E-11 T 29-03-2018 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 Gene3D G3DSA:1.20.1600.10 132 176 2.6E-4 T 29-03-2018 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 Gene3D G3DSA:2.40.50.100 68 131 3.0E-8 T 29-03-2018 CB4_RS20695 57b7b72dd679a6e4ebd6f18c52182880 476 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 188 393 6.6E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 7.3E-64 T 29-03-2018 CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 SUPERFAMILY SSF51735 5 247 9.27E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 6.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 6.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 Gene3D G3DSA:3.40.50.720 41 247 3.5E-70 T 29-03-2018 CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 Gene3D G3DSA:3.40.50.720 1 40 1.0E-10 T 29-03-2018 CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 9.6E-7 T 29-03-2018 CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.8E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.8E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17065 77fb6139e4e0a47486e4c68de50ee77d 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.8E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS15355 e50cf201a15b0efecf93196599dbff44 69 SUPERFAMILY SSF54862 1 68 7.37E-14 T 29-03-2018 CB4_RS15355 e50cf201a15b0efecf93196599dbff44 69 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 67 6.9E-22 T 29-03-2018 CB4_RS15355 e50cf201a15b0efecf93196599dbff44 69 Gene3D G3DSA:3.30.70.20 1 69 3.0E-10 T 29-03-2018 CB4_RS15355 e50cf201a15b0efecf93196599dbff44 69 PRINTS PR00352 3Fe-4S ferredoxin signature 53 65 1.2E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CB4_RS15355 e50cf201a15b0efecf93196599dbff44 69 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.2E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CB4_RS15355 e50cf201a15b0efecf93196599dbff44 69 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.2E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CB4_RS16210 ba2bf006ec9ceb0ccc3eeb5903becb45 116 SUPERFAMILY SSF52091 4 111 1.1E-28 T 29-03-2018 IPR002645 STAS domain CB4_RS16210 ba2bf006ec9ceb0ccc3eeb5903becb45 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 106 2.0E-34 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CB4_RS16210 ba2bf006ec9ceb0ccc3eeb5903becb45 116 Gene3D G3DSA:3.30.750.24 2 116 3.7E-24 T 29-03-2018 IPR002645 STAS domain CB4_RS16210 ba2bf006ec9ceb0ccc3eeb5903becb45 116 Pfam PF01740 STAS domain 5 109 2.8E-22 T 29-03-2018 IPR002645 STAS domain CB4_RS16210 ba2bf006ec9ceb0ccc3eeb5903becb45 116 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 6 110 2.8E-42 T 29-03-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 CB4_RS03870 77f606eaf2a4c775569458d48d69d6fc 511 SUPERFAMILY SSF53649 313 510 8.0E-73 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CB4_RS03870 77f606eaf2a4c775569458d48d69d6fc 511 SUPERFAMILY SSF53649 5 79 8.0E-73 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CB4_RS03870 77f606eaf2a4c775569458d48d69d6fc 511 Gene3D G3DSA:3.40.1450.10 79 305 1.2E-102 T 29-03-2018 CB4_RS03870 77f606eaf2a4c775569458d48d69d6fc 511 Pfam PF01676 Metalloenzyme superfamily 6 500 5.6E-74 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CB4_RS03870 77f606eaf2a4c775569458d48d69d6fc 511 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 84 301 1.1E-86 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03870 77f606eaf2a4c775569458d48d69d6fc 511 Gene3D G3DSA:3.40.720.10 306 509 2.2E-44 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CB4_RS03870 77f606eaf2a4c775569458d48d69d6fc 511 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 6 511 1.1E-213 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03870 77f606eaf2a4c775569458d48d69d6fc 511 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 6 511 49.139 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03870 77f606eaf2a4c775569458d48d69d6fc 511 SUPERFAMILY SSF64158 79 312 1.7E-94 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS03870 77f606eaf2a4c775569458d48d69d6fc 511 PIRSF PIRSF001492 1 511 4.3E-204 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS14050 ae5c58f62db8d503c1562cbfb7724665 414 Gene3D G3DSA:3.90.1150.10 270 410 6.8E-58 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS14050 ae5c58f62db8d503c1562cbfb7724665 414 PIRSF PIRSF000412 1 411 2.4E-166 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CB4_RS14050 ae5c58f62db8d503c1562cbfb7724665 414 Gene3D G3DSA:3.40.640.10 33 269 1.9E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS14050 ae5c58f62db8d503c1562cbfb7724665 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 52.638 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CB4_RS14050 ae5c58f62db8d503c1562cbfb7724665 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CB4_RS14050 ae5c58f62db8d503c1562cbfb7724665 414 Pfam PF00464 Serine hydroxymethyltransferase 4 380 9.0E-173 T 29-03-2018 CB4_RS14050 ae5c58f62db8d503c1562cbfb7724665 414 SUPERFAMILY SSF53383 2 412 5.84E-176 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 SUPERFAMILY SSF48452 253 368 4.17E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 SUPERFAMILY SSF52172 3 150 1.38E-30 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 Gene3D G3DSA:1.25.40.10 250 371 8.0E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 Gene3D G3DSA:1.10.10.10 129 227 3.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 Gene3D G3DSA:3.40.50.2300 1 128 4.1E-30 T 29-03-2018 CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 SMART SM00448 2 112 4.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 SMART SM00862 148 224 6.2E-6 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 219 3.4E-6 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 Pfam PF03704 Bacterial transcriptional activator domain 233 364 3.8E-7 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 SMART SM01043 231 369 1.5E-5 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 SUPERFAMILY SSF46894 134 223 8.5E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS02110 66707f20c8293e89bcdfc7c22790f0c2 371 Pfam PF00072 Response regulator receiver domain 4 110 3.9E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS08875 b2ad173e63aa56e80b391b5207e5a480 248 Gene3D G3DSA:1.10.10.10 126 239 7.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18225 81d2b1ba7a301dacfa8ca33941bee064 197 SUPERFAMILY SSF53335 8 152 9.65E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS18225 81d2b1ba7a301dacfa8ca33941bee064 197 Gene3D G3DSA:3.40.50.150 10 188 4.6E-17 T 29-03-2018 CB4_RS07980 c83f156494b4ad616df33943f6457595 289 Gene3D G3DSA:1.10.600.10 1 289 1.2E-85 T 29-03-2018 IPR008949 Isoprenoid synthase domain CB4_RS07980 c83f156494b4ad616df33943f6457595 289 SUPERFAMILY SSF48576 19 267 9.0E-84 T 29-03-2018 IPR008949 Isoprenoid synthase domain CB4_RS07980 c83f156494b4ad616df33943f6457595 289 Pfam PF00348 Polyprenyl synthetase 24 249 5.7E-59 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CB4_RS07980 c83f156494b4ad616df33943f6457595 289 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 207 219 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CB4_RS07980 c83f156494b4ad616df33943f6457595 289 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 74 90 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CB4_RS12715 6ff035f4028fb381f4aa0ceab0881d4c 379 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 259 332 1.5E-9 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS12715 6ff035f4028fb381f4aa0ceab0881d4c 379 Pfam PF12323 Helix-turn-helix domain 1 45 4.5E-16 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CB4_RS12715 6ff035f4028fb381f4aa0ceab0881d4c 379 Pfam PF01385 Probable transposase 174 292 1.3E-12 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS12715 6ff035f4028fb381f4aa0ceab0881d4c 379 Pfam PF07282 Putative transposase DNA-binding domain 306 374 1.0E-21 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 PRINTS PR00145 Argininosuccinate lyase family signature 88 110 3.9E-11 T 29-03-2018 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 PRINTS PR00145 Argininosuccinate lyase family signature 217 241 3.9E-11 T 29-03-2018 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 PRINTS PR00145 Argininosuccinate lyase family signature 262 278 3.9E-11 T 29-03-2018 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 PRINTS PR00145 Argininosuccinate lyase family signature 129 149 3.9E-11 T 29-03-2018 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 SUPERFAMILY SSF48557 3 428 1.57E-142 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 Gene3D G3DSA:1.10.40.30 350 429 4.9E-27 T 29-03-2018 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 429 6.5E-182 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 SMART SM00998 350 430 2.0E-40 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 ProSitePatterns PS00163 Fumarate lyases signature. 262 271 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 PRINTS PR00149 Fumarate lyase superfamily signature 217 244 3.8E-28 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 PRINTS PR00149 Fumarate lyase superfamily signature 262 278 3.8E-28 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 PRINTS PR00149 Fumarate lyase superfamily signature 89 107 3.8E-28 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 3.8E-28 T 29-03-2018 IPR000362 Fumarate lyase family CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 Gene3D G3DSA:1.20.200.10 94 349 5.8E-83 T 29-03-2018 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 Gene3D G3DSA:1.10.275.10 2 93 4.3E-25 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 Pfam PF10397 Adenylosuccinate lyase C-terminus 351 428 7.0E-26 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CB4_RS20390 b3fa1e56680ea1f215734c1effccf9be 431 Pfam PF00206 Lyase 6 287 2.9E-76 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 PRINTS PR01035 Tetracycline resistance protein signature 282 303 4.6E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 PRINTS PR01035 Tetracycline resistance protein signature 343 366 4.6E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 PRINTS PR01035 Tetracycline resistance protein signature 167 187 4.6E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 PRINTS PR01035 Tetracycline resistance protein signature 18 34 4.6E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 PRINTS PR01035 Tetracycline resistance protein signature 139 161 4.6E-10 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 SUPERFAMILY SSF103473 1 394 1.2E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 Gene3D G3DSA:1.20.1250.20 201 408 2.9E-28 T 29-03-2018 CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 Pfam PF07690 Major Facilitator Superfamily 17 359 2.9E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 Gene3D G3DSA:1.20.1250.20 1 200 2.9E-34 T 29-03-2018 CB4_RS12240 f92a65015becfe2db88ee15c887d95fc 413 ProSitePatterns PS00217 Sugar transport proteins signature 2. 315 340 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CB4_RS10255 62c8d9790218cfbb5a5949d2467db7d9 253 Gene3D G3DSA:3.90.226.10 55 251 7.6E-28 T 29-03-2018 CB4_RS10255 62c8d9790218cfbb5a5949d2467db7d9 253 SUPERFAMILY SSF52096 48 233 4.32E-37 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS10255 62c8d9790218cfbb5a5949d2467db7d9 253 Pfam PF00574 Clp protease 58 226 2.3E-32 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CB4_RS07885 5c9ecd1d0a7d2bdeec6db76279f82eaf 265 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 158 185 3.2E-12 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS07885 5c9ecd1d0a7d2bdeec6db76279f82eaf 265 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 187 216 3.2E-12 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS07885 5c9ecd1d0a7d2bdeec6db76279f82eaf 265 SMART SM00283 85 261 9.6E-4 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS07885 5c9ecd1d0a7d2bdeec6db76279f82eaf 265 SUPERFAMILY SSF58104 101 262 9.29E-37 T 29-03-2018 CB4_RS07885 5c9ecd1d0a7d2bdeec6db76279f82eaf 265 Gene3D G3DSA:1.10.287.950 96 264 1.3E-35 T 29-03-2018 CB4_RS07885 5c9ecd1d0a7d2bdeec6db76279f82eaf 265 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 132 260 2.1E-26 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS10415 dbce0ec1ebc6ac3cf7d57959a997b22f 598 Gene3D G3DSA:1.20.140.10 450 568 1.0E-5 T 29-03-2018 CB4_RS10415 dbce0ec1ebc6ac3cf7d57959a997b22f 598 Gene3D G3DSA:2.40.110.10 145 239 2.4E-31 T 29-03-2018 CB4_RS10415 dbce0ec1ebc6ac3cf7d57959a997b22f 598 SUPERFAMILY SSF47203 249 421 1.77E-45 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS10415 dbce0ec1ebc6ac3cf7d57959a997b22f 598 Gene3D G3DSA:1.20.140.10 240 428 4.2E-53 T 29-03-2018 CB4_RS10415 dbce0ec1ebc6ac3cf7d57959a997b22f 598 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 146 239 3.0E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CB4_RS10415 dbce0ec1ebc6ac3cf7d57959a997b22f 598 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 142 2.7E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS10415 dbce0ec1ebc6ac3cf7d57959a997b22f 598 SUPERFAMILY SSF56645 24 262 4.32E-70 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CB4_RS10415 dbce0ec1ebc6ac3cf7d57959a997b22f 598 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 251 415 1.5E-35 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS10415 dbce0ec1ebc6ac3cf7d57959a997b22f 598 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 148 160 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS10415 dbce0ec1ebc6ac3cf7d57959a997b22f 598 Gene3D G3DSA:1.10.540.10 2 144 3.5E-34 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS20500 21a94c5fb6c565097ae5159037d81f73 159 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 17 136 7.3E-38 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CB4_RS20500 21a94c5fb6c565097ae5159037d81f73 159 SUPERFAMILY SSF52540 28 147 2.97E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS20500 21a94c5fb6c565097ae5159037d81f73 159 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 13 133 1.3E-35 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CB4_RS20500 21a94c5fb6c565097ae5159037d81f73 159 Gene3D G3DSA:3.40.50.300 4 154 1.3E-46 T 29-03-2018 CB4_RS11235 987603422877924c152d0d03c45096e5 739 Gene3D G3DSA:1.10.460.10 164 349 1.7E-37 T 29-03-2018 CB4_RS11235 987603422877924c152d0d03c45096e5 739 Gene3D G3DSA:1.10.460.10 479 618 7.6E-23 T 29-03-2018 CB4_RS11235 987603422877924c152d0d03c45096e5 739 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 315 324 8.2E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS11235 987603422877924c152d0d03c45096e5 739 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 523 537 8.2E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS11235 987603422877924c152d0d03c45096e5 739 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 8.2E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS11235 987603422877924c152d0d03c45096e5 739 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 397 413 8.2E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS11235 987603422877924c152d0d03c45096e5 739 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 8.2E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS11235 987603422877924c152d0d03c45096e5 739 Gene3D G3DSA:2.70.20.10 361 478 9.5E-25 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CB4_RS11235 987603422877924c152d0d03c45096e5 739 SMART SM00436 130 225 4.1E-30 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CB4_RS11235 987603422877924c152d0d03c45096e5 739 SUPERFAMILY SSF56712 2 610 8.89E-172 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CB4_RS11235 987603422877924c152d0d03c45096e5 739 SMART SM00493 1 130 3.8E-11 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS11235 987603422877924c152d0d03c45096e5 739 Pfam PF01751 Toprim domain 3 138 2.1E-10 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS11235 987603422877924c152d0d03c45096e5 739 Pfam PF01131 DNA topoisomerase 158 595 8.7E-119 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CB4_RS11235 987603422877924c152d0d03c45096e5 739 Gene3D G3DSA:3.40.50.140 1 157 7.5E-34 T 29-03-2018 CB4_RS11235 987603422877924c152d0d03c45096e5 739 Pfam PF13342 C-terminal repeat of topoisomerase 672 731 4.6E-16 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat CB4_RS11235 987603422877924c152d0d03c45096e5 739 Gene3D G3DSA:3.30.65.10 630 689 1.5E-5 T 29-03-2018 CB4_RS11235 987603422877924c152d0d03c45096e5 739 SMART SM00437 273 560 9.7E-81 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CB4_RS11235 987603422877924c152d0d03c45096e5 739 TIGRFAM TIGR01056 topB: DNA topoisomerase III 2 716 1.2E-185 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CB4_RS01530 0cd99b8a3f87592cc89a94ee43b53a37 288 Pfam PF00398 Ribosomal RNA adenine dimethylase 21 287 3.2E-69 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CB4_RS01530 0cd99b8a3f87592cc89a94ee43b53a37 288 SMART SM00650 37 213 1.3E-75 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CB4_RS01530 0cd99b8a3f87592cc89a94ee43b53a37 288 Gene3D G3DSA:3.40.50.150 3 226 6.0E-58 T 29-03-2018 CB4_RS01530 0cd99b8a3f87592cc89a94ee43b53a37 288 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 21 288 54.492 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CB4_RS01530 0cd99b8a3f87592cc89a94ee43b53a37 288 Gene3D G3DSA:1.10.8.100 227 288 4.0E-23 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CB4_RS01530 0cd99b8a3f87592cc89a94ee43b53a37 288 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 21 286 5.6E-85 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CB4_RS01530 0cd99b8a3f87592cc89a94ee43b53a37 288 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 53 80 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CB4_RS01530 0cd99b8a3f87592cc89a94ee43b53a37 288 SUPERFAMILY SSF53335 18 287 2.71E-72 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 SUPERFAMILY SSF51735 3 246 3.77E-93 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 1.7E-109 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.4E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.4E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.4E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 3.4E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.4E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.4E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 1.3E-6 T 29-03-2018 CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 3.3E-72 T 29-03-2018 CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 Gene3D G3DSA:3.40.50.10090 1 47 5.2E-10 T 29-03-2018 CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.0E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.0E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.0E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08620 95020f5542c48aa97e7bca12f3277569 246 Gene3D G3DSA:3.40.50.720 48 246 3.7E-72 T 29-03-2018 CB4_RS01805 0e82280f38ebe485e1caf645789d0062 548 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 216 1.8E-37 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01805 0e82280f38ebe485e1caf645789d0062 548 SUPERFAMILY SSF53790 3 260 4.84E-57 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01805 0e82280f38ebe485e1caf645789d0062 548 Gene3D G3DSA:3.30.950.10 130 247 5.3E-53 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01805 0e82280f38ebe485e1caf645789d0062 548 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 412 524 1.3E-7 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CB4_RS01805 0e82280f38ebe485e1caf645789d0062 548 Gene3D G3DSA:3.40.1010.10 3 129 5.2E-33 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01805 0e82280f38ebe485e1caf645789d0062 548 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 446 462 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CB4_RS01805 0e82280f38ebe485e1caf645789d0062 548 SUPERFAMILY SSF56014 404 525 1.83E-21 T 29-03-2018 CB4_RS01805 0e82280f38ebe485e1caf645789d0062 548 Gene3D G3DSA:3.30.413.10 402 534 3.0E-19 T 29-03-2018 CB4_RS01805 0e82280f38ebe485e1caf645789d0062 548 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 6 249 3.0E-97 T 29-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 SMART SM00382 84 222 3.7E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 PRINTS PR00819 CbxX/CfqX superfamily signature 169 181 2.6E-60 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 PRINTS PR00819 CbxX/CfqX superfamily signature 190 207 2.6E-60 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 PRINTS PR00819 CbxX/CfqX superfamily signature 139 158 2.6E-60 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 PRINTS PR00819 CbxX/CfqX superfamily signature 207 226 2.6E-60 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 PRINTS PR00819 CbxX/CfqX superfamily signature 87 102 2.6E-60 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 PRINTS PR00819 CbxX/CfqX superfamily signature 47 61 2.6E-60 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 PRINTS PR00819 CbxX/CfqX superfamily signature 125 139 2.6E-60 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 PRINTS PR00819 CbxX/CfqX superfamily signature 266 278 2.6E-60 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 88 218 1.4E-18 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 Gene3D G3DSA:3.40.50.300 18 219 2.7E-24 T 29-03-2018 CB4_RS14130 81395a04e67d2d7bc82f4f04ebb032d4 310 SUPERFAMILY SSF52540 48 288 8.74E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00925 d85f5822747fb2277cec4b627626e7a5 220 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.801 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CB4_RS00925 d85f5822747fb2277cec4b627626e7a5 220 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.4E-39 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00925 d85f5822747fb2277cec4b627626e7a5 220 SMART SM00322 59 124 8.5E-7 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CB4_RS00925 d85f5822747fb2277cec4b627626e7a5 220 SUPERFAMILY SSF54814 2 105 2.62E-36 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CB4_RS00925 d85f5822747fb2277cec4b627626e7a5 220 Pfam PF07650 KH domain 37 109 1.3E-20 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00925 d85f5822747fb2277cec4b627626e7a5 220 Gene3D G3DSA:3.30.300.20 17 106 5.9E-31 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CB4_RS00925 d85f5822747fb2277cec4b627626e7a5 220 Gene3D G3DSA:3.30.1140.32 107 207 6.2E-37 T 29-03-2018 CB4_RS00925 d85f5822747fb2277cec4b627626e7a5 220 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00925 d85f5822747fb2277cec4b627626e7a5 220 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 3.0E-95 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CB4_RS00925 d85f5822747fb2277cec4b627626e7a5 220 SUPERFAMILY SSF54821 106 205 4.97E-38 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS11770 e47727f9797d4b499627fa841c92e9d8 206 SUPERFAMILY SSF55729 78 170 2.47E-10 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS11770 e47727f9797d4b499627fa841c92e9d8 206 Gene3D G3DSA:3.40.630.30 25 191 1.1E-9 T 29-03-2018 CB4_RS11770 e47727f9797d4b499627fa841c92e9d8 206 Pfam PF00583 Acetyltransferase (GNAT) family 87 166 5.9E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 Pfam PF00391 PEP-utilising enzyme, mobile domain 504 573 2.8E-20 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 468 6.4E-39 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.1E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 PRINTS PR01050 Pyruvate kinase family signature 310 326 1.1E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 PRINTS PR01050 Pyruvate kinase family signature 184 198 1.1E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 PRINTS PR01050 Pyruvate kinase family signature 214 240 1.1E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 PRINTS PR01050 Pyruvate kinase family signature 241 265 1.1E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 PRINTS PR01050 Pyruvate kinase family signature 291 309 1.1E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 PRINTS PR01050 Pyruvate kinase family signature 266 290 1.1E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 SUPERFAMILY SSF52009 463 579 5.36E-29 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 Gene3D G3DSA:3.20.20.60 1 81 6.5E-20 T 29-03-2018 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 SUPERFAMILY SSF51621 1 75 1.64E-103 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 SUPERFAMILY SSF51621 165 341 1.64E-103 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 470 1.3E-189 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 Gene3D G3DSA:3.20.20.60 166 318 6.2E-66 T 29-03-2018 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 Pfam PF00224 Pyruvate kinase, barrel domain 1 340 4.6E-150 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 SUPERFAMILY SSF52935 320 471 4.97E-44 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 Gene3D G3DSA:3.40.1380.20 319 471 2.6E-57 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 SUPERFAMILY SSF50800 70 165 1.17E-28 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 Gene3D G3DSA:2.40.33.10 82 165 4.0E-32 T 29-03-2018 CB4_RS18415 94f432af4c52ba52d11483c170c4f87e 583 Gene3D G3DSA:3.50.30.10 472 583 1.9E-26 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CB4_RS11685 4579ee09528fafbb583726680f1d36c3 72 Pfam PF08858 IDEAL domain 15 44 6.2E-9 T 29-03-2018 IPR014957 IDEAL domain CB4_RS11685 4579ee09528fafbb583726680f1d36c3 72 SMART SM00914 15 51 0.0018 T 29-03-2018 IPR014957 IDEAL domain CB4_RS02880 5a48e9f108f5978e1ae48bc2b267dae9 164 Pfam PF02659 Putative manganese efflux pump 16 163 7.0E-42 T 29-03-2018 IPR003810 Putative manganese efflux pump CB4_RS02880 5a48e9f108f5978e1ae48bc2b267dae9 164 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 164 18.868 T 29-03-2018 IPR022929 Putative manganese efflux pump MntP CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 115 123 8.2E-18 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 8.2E-18 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 68 78 8.2E-18 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 8.2E-18 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 7.3E-21 T 29-03-2018 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 7.3E-21 T 29-03-2018 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 7.3E-21 T 29-03-2018 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 Gene3D G3DSA:3.40.50.720 235 330 1.9E-5 T 29-03-2018 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 SUPERFAMILY SSF51905 10 316 7.41E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 Gene3D G3DSA:3.50.50.60 3 139 1.0E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 300 8.6E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 Gene3D G3DSA:3.50.50.60 140 234 4.8E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS05265 3abaaa0f23688a54d27da7feb2204d7b 332 Hamap MF_01685 Ferredoxin--NADP reductase. 9 330 44.755 T 29-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CB4_RS01505 502eba2e6279426325e12c97c0ac05e3 272 SUPERFAMILY SSF53271 86 260 1.25E-38 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CB4_RS01505 502eba2e6279426325e12c97c0ac05e3 272 Gene3D G3DSA:3.40.50.2020 75 270 1.2E-31 T 29-03-2018 CB4_RS01505 502eba2e6279426325e12c97c0ac05e3 272 Pfam PF00156 Phosphoribosyl transferase domain 112 254 3.4E-22 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CB4_RS01505 502eba2e6279426325e12c97c0ac05e3 272 Pfam PF09182 Bacterial purine repressor, N-terminal 5 74 7.0E-31 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CB4_RS01505 502eba2e6279426325e12c97c0ac05e3 272 Gene3D G3DSA:1.10.10.10 1 74 8.8E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS01505 502eba2e6279426325e12c97c0ac05e3 272 SUPERFAMILY SSF46785 3 74 5.53E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS01505 502eba2e6279426325e12c97c0ac05e3 272 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 269 2.0E-114 T 29-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CB4_RS01505 502eba2e6279426325e12c97c0ac05e3 272 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 10 75 8.0E-22 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CB4_RS13615 2f459b8f134687d0caa8f1db6adcf0ff 108 Gene3D G3DSA:1.10.287.1080 1 108 3.4E-16 T 29-03-2018 CB4_RS13615 2f459b8f134687d0caa8f1db6adcf0ff 108 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 103 4.3E-12 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CB4_RS13615 2f459b8f134687d0caa8f1db6adcf0ff 108 SUPERFAMILY SSF101386 1 105 3.74E-23 T 29-03-2018 CB4_RS13615 2f459b8f134687d0caa8f1db6adcf0ff 108 PIRSF PIRSF036521 1 107 1.7E-48 T 29-03-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related CB4_RS15170 d55bf17eba867c2a38c92e2a90561d88 196 Pfam PF02441 Flavoprotein 5 175 1.3E-27 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CB4_RS15170 d55bf17eba867c2a38c92e2a90561d88 196 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 3 196 35.592 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CB4_RS15170 d55bf17eba867c2a38c92e2a90561d88 196 SUPERFAMILY SSF52507 5 196 4.71E-60 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CB4_RS15170 d55bf17eba867c2a38c92e2a90561d88 196 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 5 194 7.4E-62 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CB4_RS15170 d55bf17eba867c2a38c92e2a90561d88 196 Gene3D G3DSA:3.40.50.1950 3 196 1.4E-53 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CB4_RS07305 aed8ff9b9493fac471097fbd002d108e 253 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 31 237 5.4E-92 T 29-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 CB4_RS07305 aed8ff9b9493fac471097fbd002d108e 253 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 31 246 29.719 T 29-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 CB4_RS07305 aed8ff9b9493fac471097fbd002d108e 253 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 32 238 1.8E-53 T 29-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00710 117 138 190.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00710 283 304 1600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00710 191 212 94.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00710 235 260 690.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00710 169 190 1100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00710 306 353 5700.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00710 89 110 1400.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00710 261 282 1200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00710 213 234 950.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 163 206 5.1E-5 T 29-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 212 247 8.3E-5 T 29-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 257 296 3.7E-6 T 29-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 Gene3D G3DSA:2.160.20.10 29 262 1.0E-43 T 29-03-2018 IPR012334 Pectin lyase fold CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 Gene3D G3DSA:2.160.20.10 263 398 5.9E-9 T 29-03-2018 IPR012334 Pectin lyase fold CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SUPERFAMILY SSF51126 30 389 6.92E-59 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00722 239 370 2.1 T 29-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 SMART SM00722 43 189 3.1E-6 T 29-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 Pfam PF05048 Periplasmic copper-binding protein (NosD) 151 377 3.0E-39 T 29-03-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CB4_RS04880 1bc1da83c9c4b92285ba4dff9a543455 411 TIGRFAM TIGR04247 NosD_copper_fam: nitrous oxide reductase family maturation protein NosD 36 391 1.0E-98 T 29-03-2018 IPR026464 Nitrous oxide reductase family maturation protein NosD CB4_RS08185 c77d9bd090758c66584b729ad6389744 71 Gene3D G3DSA:2.40.50.100 1 71 1.1E-18 T 29-03-2018 CB4_RS08185 c77d9bd090758c66584b729ad6389744 71 SUPERFAMILY SSF51230 3 70 1.57E-19 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS08185 c77d9bd090758c66584b729ad6389744 71 Pfam PF00364 Biotin-requiring enzyme 3 69 1.1E-15 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CB4_RS16125 671afd28d816bcef9912e9569d1a5d40 442 Pfam PF00202 Aminotransferase class-III 31 437 1.0E-129 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS16125 671afd28d816bcef9912e9569d1a5d40 442 Gene3D G3DSA:3.90.1150.10 321 442 1.7E-32 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS16125 671afd28d816bcef9912e9569d1a5d40 442 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 289 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS16125 671afd28d816bcef9912e9569d1a5d40 442 Gene3D G3DSA:3.40.640.10 58 320 5.6E-86 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS16125 671afd28d816bcef9912e9569d1a5d40 442 PIRSF PIRSF000521 1 138 3.6E-10 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS16125 671afd28d816bcef9912e9569d1a5d40 442 PIRSF PIRSF000521 131 440 1.3E-40 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS16125 671afd28d816bcef9912e9569d1a5d40 442 SUPERFAMILY SSF53383 30 437 2.18E-137 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS16125 671afd28d816bcef9912e9569d1a5d40 442 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 19 439 6.5E-180 T 29-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CB4_RS16765 f8f38812391139247f27c485e5dbd96a 238 SMART SM01236 75 186 2.2E-10 T 29-03-2018 CB4_RS16765 f8f38812391139247f27c485e5dbd96a 238 Pfam PF14518 Iron-containing redox enzyme 41 212 1.9E-12 T 29-03-2018 IPR028201 PqqC-like protein CB4_RS16765 f8f38812391139247f27c485e5dbd96a 238 Gene3D G3DSA:1.20.910.10 2 237 1.7E-29 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CB4_RS16765 f8f38812391139247f27c485e5dbd96a 238 SUPERFAMILY SSF48613 10 231 7.91E-23 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CB4_RS12160 3fe50d0b6389af9bd9253a717cc118ee 248 Gene3D G3DSA:2.30.30.370 1 36 1.6E-17 T 29-03-2018 CB4_RS12160 3fe50d0b6389af9bd9253a717cc118ee 248 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 245 4.2E-125 T 29-03-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 CB4_RS12160 3fe50d0b6389af9bd9253a717cc118ee 248 SUPERFAMILY SSF56529 36 245 1.7E-74 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS12160 3fe50d0b6389af9bd9253a717cc118ee 248 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 46 244 3.1E-60 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS12160 3fe50d0b6389af9bd9253a717cc118ee 248 Gene3D G3DSA:3.90.850.10 37 248 1.8E-70 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS00540 93ba2c8dd845888d127e0ca967b069d9 461 SUPERFAMILY SSF53383 97 457 6.4E-49 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS00540 93ba2c8dd845888d127e0ca967b069d9 461 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 3.3E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS00540 93ba2c8dd845888d127e0ca967b069d9 461 SUPERFAMILY SSF46785 11 82 6.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00540 93ba2c8dd845888d127e0ca967b069d9 461 SMART SM00345 19 78 2.0E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS00540 93ba2c8dd845888d127e0ca967b069d9 461 Gene3D G3DSA:3.90.1150.10 350 461 4.2E-12 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS00540 93ba2c8dd845888d127e0ca967b069d9 461 Gene3D G3DSA:1.10.10.10 2 92 9.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00540 93ba2c8dd845888d127e0ca967b069d9 461 Gene3D G3DSA:3.40.640.10 139 349 2.1E-14 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS07675 3041c817d9db4c1671213dd591c2bfd5 569 SUPERFAMILY SSF52540 16 256 8.11E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07675 3041c817d9db4c1671213dd591c2bfd5 569 Gene3D G3DSA:3.40.50.10810 37 273 5.1E-39 T 29-03-2018 CB4_RS07675 3041c817d9db4c1671213dd591c2bfd5 569 Gene3D G3DSA:3.40.50.300 349 507 1.5E-35 T 29-03-2018 CB4_RS07675 3041c817d9db4c1671213dd591c2bfd5 569 SUPERFAMILY SSF52540 353 517 4.73E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07675 3041c817d9db4c1671213dd591c2bfd5 569 SUPERFAMILY SSF52540 169 223 4.73E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07675 3041c817d9db4c1671213dd591c2bfd5 569 SMART SM00487 57 237 4.3E-31 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS07675 3041c817d9db4c1671213dd591c2bfd5 569 Pfam PF00271 Helicase conserved C-terminal domain 367 469 8.4E-19 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS07675 3041c817d9db4c1671213dd591c2bfd5 569 Pfam PF00176 SNF2 family N-terminal domain 79 321 2.8E-33 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CB4_RS07675 3041c817d9db4c1671213dd591c2bfd5 569 SMART SM00490 389 469 1.6E-19 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS15580 2c117611fb34b84c5e496cbe245b1cd7 302 Gene3D G3DSA:3.40.50.300 103 278 3.5E-19 T 29-03-2018 CB4_RS15580 2c117611fb34b84c5e496cbe245b1cd7 302 SUPERFAMILY SSF52540 106 274 7.87E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15580 2c117611fb34b84c5e496cbe245b1cd7 302 Pfam PF01695 IstB-like ATP binding protein 140 248 2.5E-20 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CB4_RS07090 58f6ef9b6c94bf156012a30dcb9d2b2e 323 Gene3D G3DSA:3.30.1370.10 2 95 7.2E-5 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CB4_RS07090 58f6ef9b6c94bf156012a30dcb9d2b2e 323 Gene3D G3DSA:3.40.50.300 111 316 6.7E-31 T 29-03-2018 CB4_RS07090 58f6ef9b6c94bf156012a30dcb9d2b2e 323 SUPERFAMILY SSF52540 112 292 2.44E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07090 58f6ef9b6c94bf156012a30dcb9d2b2e 323 SUPERFAMILY SSF54791 17 61 9.27E-5 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CB4_RS07090 58f6ef9b6c94bf156012a30dcb9d2b2e 323 Pfam PF02562 PhoH-like protein 113 316 3.3E-95 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CB4_RS07205 4567d7044d2aee0157bf934ef6b92748 260 SUPERFAMILY SSF53850 5 259 2.89E-66 T 29-03-2018 CB4_RS07205 4567d7044d2aee0157bf934ef6b92748 260 Gene3D G3DSA:3.40.190.10 150 260 3.4E-17 T 29-03-2018 CB4_RS07205 4567d7044d2aee0157bf934ef6b92748 260 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CB4_RS07205 4567d7044d2aee0157bf934ef6b92748 260 Gene3D G3DSA:3.40.190.10 1 149 3.3E-38 T 29-03-2018 CB4_RS07205 4567d7044d2aee0157bf934ef6b92748 260 SMART SM00062 37 260 2.6E-62 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CB4_RS07205 4567d7044d2aee0157bf934ef6b92748 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 259 4.3E-61 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CB4_RS11305 b8b75dde72f64425721519c5d91b16cc 311 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 220 309 4.9E-33 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS11305 b8b75dde72f64425721519c5d91b16cc 311 Gene3D G3DSA:3.40.47.10 1 161 1.0E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS11305 b8b75dde72f64425721519c5d91b16cc 311 Gene3D G3DSA:3.40.47.10 162 308 1.0E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS11305 b8b75dde72f64425721519c5d91b16cc 311 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 3 309 1.6E-120 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS11305 b8b75dde72f64425721519c5d91b16cc 311 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 185 9.0E-33 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS11305 b8b75dde72f64425721519c5d91b16cc 311 SUPERFAMILY SSF53901 3 309 5.77E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS11305 b8b75dde72f64425721519c5d91b16cc 311 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 309 69.819 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CB4_RS15510 53a62a80b0aa92167662aec6c84d708e 669 Pfam PF04860 Phage portal protein 43 370 3.2E-100 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CB4_RS15510 53a62a80b0aa92167662aec6c84d708e 669 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 35 376 9.8E-90 T 29-03-2018 IPR006427 Phage portal protein, HK97 CB4_RS15615 ad1212ccb8f9f9b3b8ce21f7a6d72843 238 SMART SM00530 32 89 1.3E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS15615 ad1212ccb8f9f9b3b8ce21f7a6d72843 238 SMART SM00530 123 178 5.4E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS15615 ad1212ccb8f9f9b3b8ce21f7a6d72843 238 SUPERFAMILY SSF47413 24 90 9.57E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS15615 ad1212ccb8f9f9b3b8ce21f7a6d72843 238 Gene3D G3DSA:1.10.3100.10 115 238 7.4E-22 T 29-03-2018 IPR027910 YdiL-like domain CB4_RS15615 ad1212ccb8f9f9b3b8ce21f7a6d72843 238 SUPERFAMILY SSF47413 118 181 5.38E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS15615 ad1212ccb8f9f9b3b8ce21f7a6d72843 238 Pfam PF01381 Helix-turn-helix 35 89 1.6E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS15615 ad1212ccb8f9f9b3b8ce21f7a6d72843 238 Pfam PF01381 Helix-turn-helix 124 178 1.8E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS15615 ad1212ccb8f9f9b3b8ce21f7a6d72843 238 Gene3D G3DSA:1.10.260.40 21 114 2.4E-13 T 29-03-2018 CB4_RS08140 7a8b3b09ed6509f791f0ce9ad7f6d39e 210 SUPERFAMILY SSF56281 1 207 4.32E-54 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS08140 7a8b3b09ed6509f791f0ce9ad7f6d39e 210 Gene3D G3DSA:3.60.15.10 1 203 2.3E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS08140 7a8b3b09ed6509f791f0ce9ad7f6d39e 210 SMART SM00849 12 190 1.4E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS08140 7a8b3b09ed6509f791f0ce9ad7f6d39e 210 Pfam PF00753 Metallo-beta-lactamase superfamily 9 190 1.2E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS07145 6c6feac625a0abfea824405d879f51e7 276 Pfam PF03618 Kinase/pyrophosphorylase 11 266 1.0E-97 T 29-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CB4_RS07145 6c6feac625a0abfea824405d879f51e7 276 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 9 271 58.732 T 29-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CB4_RS00380 ad9f3484eb591a779e56fb5b244f2656 184 Pfam PF00484 Carbonic anhydrase 34 177 5.6E-17 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CB4_RS00380 ad9f3484eb591a779e56fb5b244f2656 184 SUPERFAMILY SSF53056 4 181 4.58E-40 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CB4_RS00380 ad9f3484eb591a779e56fb5b244f2656 184 SMART SM00947 26 182 1.2E-31 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CB4_RS00380 ad9f3484eb591a779e56fb5b244f2656 184 Gene3D G3DSA:3.40.1050.10 1 182 5.0E-34 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CB4_RS06055 4e2123366c84695c680e217830901755 139 Gene3D G3DSA:1.10.10.10 1 139 5.3E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS06055 4e2123366c84695c680e217830901755 139 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CB4_RS06055 4e2123366c84695c680e217830901755 139 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 124 1.4E-34 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CB4_RS06055 4e2123366c84695c680e217830901755 139 SUPERFAMILY SSF46785 2 124 9.09E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS06055 4e2123366c84695c680e217830901755 139 Pfam PF02082 Transcriptional regulator 1 82 3.6E-28 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 Pfam PF02503 Polyphosphate kinase middle domain 135 336 4.3E-75 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 PIRSF PIRSF015589 1 712 2.1E-294 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 Pfam PF13090 Polyphosphate kinase C-terminal domain 345 691 2.8E-160 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 Gene3D G3DSA:3.30.1840.10 126 315 9.4E-74 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 Hamap MF_00347 Polyphosphate kinase [ppk]. 18 697 30.55 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 SUPERFAMILY SSF140356 18 121 6.67E-39 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 SUPERFAMILY SSF143724 124 328 5.89E-65 T 29-03-2018 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 Gene3D G3DSA:1.20.58.310 22 125 2.4E-39 T 29-03-2018 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 SUPERFAMILY SSF56024 516 697 7.85E-70 T 29-03-2018 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 Pfam PF13089 Polyphosphate kinase N-terminal domain 20 126 6.5E-41 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 Gene3D G3DSA:3.30.870.10 338 514 2.5E-19 T 29-03-2018 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 Gene3D G3DSA:3.30.870.10 515 702 1.1E-34 T 29-03-2018 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 SUPERFAMILY SSF56024 330 511 4.32E-59 T 29-03-2018 CB4_RS05655 2a7056d344df75652da47f188d4827f2 719 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 19 691 3.0E-286 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 Gene3D G3DSA:3.30.70.270 138 311 4.1E-53 T 29-03-2018 CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 SMART SM00086 89 131 1.1E-5 T 29-03-2018 IPR001610 PAC motif CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 SMART SM00267 131 304 2.0E-52 T 29-03-2018 IPR000160 GGDEF domain CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 SUPERFAMILY SSF55073 147 304 3.92E-43 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 Pfam PF00563 EAL domain 320 554 7.4E-79 T 29-03-2018 IPR001633 EAL domain CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 Pfam PF00990 Diguanylate cyclase, GGDEF domain 142 300 2.3E-43 T 29-03-2018 IPR000160 GGDEF domain CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 SMART SM00052 314 559 4.3E-122 T 29-03-2018 IPR001633 EAL domain CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 Gene3D G3DSA:3.20.20.450 312 573 6.6E-105 T 29-03-2018 IPR001633 EAL domain CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 SUPERFAMILY SSF55785 29 128 1.29E-24 T 29-03-2018 IPR000014 PAS domain CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 25 137 5.9E-18 T 29-03-2018 IPR000014 PAS domain CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 140 303 7.1E-38 T 29-03-2018 IPR000160 GGDEF domain CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 SUPERFAMILY SSF141868 319 567 9.55E-94 T 29-03-2018 IPR001633 EAL domain CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 Gene3D G3DSA:3.40.50.10600 15 137 1.8E-28 T 29-03-2018 CB4_RS17845 42ff6bbe4f9df0b3b845b9f6d446ea34 575 Pfam PF13426 PAS domain 31 129 2.1E-12 T 29-03-2018 IPR000014 PAS domain CB4_RS00535 b936a84cedbf95096436f4edca714f77 408 Gene3D G3DSA:1.10.3290.10 58 327 3.7E-38 T 29-03-2018 IPR003812 Fido domain CB4_RS00535 b936a84cedbf95096436f4edca714f77 408 Pfam PF02661 Fic/DOC family 151 253 7.4E-18 T 29-03-2018 IPR003812 Fido domain CB4_RS00535 b936a84cedbf95096436f4edca714f77 408 SUPERFAMILY SSF140931 143 316 5.1E-23 T 29-03-2018 IPR003812 Fido domain CB4_RS03615 8fb95b019dd9c78c1bf4959b5648268d 433 Gene3D G3DSA:2.30.42.10 283 384 3.8E-12 T 29-03-2018 CB4_RS03615 8fb95b019dd9c78c1bf4959b5648268d 433 SMART SM00228 276 367 5.3E-5 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS03615 8fb95b019dd9c78c1bf4959b5648268d 433 SUPERFAMILY SSF50156 309 392 1.45E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS09185 77f1c1bc0afdce38cd938badd01897c1 360 SUPERFAMILY SSF160544 250 357 1.23E-42 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CB4_RS09185 77f1c1bc0afdce38cd938badd01897c1 360 Pfam PF01312 FlhB HrpN YscU SpaS Family 13 353 3.7E-134 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CB4_RS09185 77f1c1bc0afdce38cd938badd01897c1 360 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 14 358 2.6E-132 T 29-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 CB4_RS09185 77f1c1bc0afdce38cd938badd01897c1 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 234 251 2.7E-40 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CB4_RS09185 77f1c1bc0afdce38cd938badd01897c1 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 214 232 2.7E-40 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CB4_RS09185 77f1c1bc0afdce38cd938badd01897c1 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 278 293 2.7E-40 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CB4_RS09185 77f1c1bc0afdce38cd938badd01897c1 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 16 38 2.7E-40 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CB4_RS09185 77f1c1bc0afdce38cd938badd01897c1 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 308 329 2.7E-40 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CB4_RS09185 77f1c1bc0afdce38cd938badd01897c1 360 Gene3D G3DSA:3.40.1690.10 224 359 8.2E-58 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CB4_RS12370 79117cb2d9f7cec6da6da3e2177eb13a 133 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 3 119 29.148 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CB4_RS12370 79117cb2d9f7cec6da6da3e2177eb13a 133 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 5 115 2.7E-42 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CB4_RS12370 79117cb2d9f7cec6da6da3e2177eb13a 133 SUPERFAMILY SSF56276 5 116 4.71E-40 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CB4_RS12370 79117cb2d9f7cec6da6da3e2177eb13a 133 Gene3D G3DSA:3.60.90.10 1 130 9.3E-44 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CB4_RS12370 79117cb2d9f7cec6da6da3e2177eb13a 133 Pfam PF02675 S-adenosylmethionine decarboxylase 9 115 9.0E-37 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CB4_RS03940 11ae89729b3fe373869eb1e991ada730 224 Pfam PF00877 NlpC/P60 family 115 221 8.5E-22 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CB4_RS03940 11ae89729b3fe373869eb1e991ada730 224 SUPERFAMILY SSF54001 94 223 3.73E-31 T 29-03-2018 CB4_RS03940 11ae89729b3fe373869eb1e991ada730 224 Gene3D G3DSA:3.90.1720.10 90 224 7.2E-33 T 29-03-2018 CB4_RS01230 4a9231ec1addd340d3aea7c28462f0a1 364 Gene3D G3DSA:3.40.50.1010 159 295 2.2E-27 T 29-03-2018 IPR029060 PIN domain-like CB4_RS01230 4a9231ec1addd340d3aea7c28462f0a1 364 SMART SM00670 164 271 1.4E-10 T 29-03-2018 IPR002716 PIN domain CB4_RS01230 4a9231ec1addd340d3aea7c28462f0a1 364 SUPERFAMILY SSF88723 165 292 7.06E-24 T 29-03-2018 IPR029060 PIN domain-like CB4_RS01230 4a9231ec1addd340d3aea7c28462f0a1 364 Pfam PF01938 TRAM domain 295 348 1.1E-5 T 29-03-2018 IPR002792 TRAM domain CB4_RS18345 ceeb821c84b9e15dfe111b80ac019a9b 187 Gene3D G3DSA:1.10.530.10 29 186 5.3E-38 T 29-03-2018 CB4_RS18345 ceeb821c84b9e15dfe111b80ac019a9b 187 Pfam PF01464 Transglycosylase SLT domain 40 150 1.4E-30 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CB4_RS18345 ceeb821c84b9e15dfe111b80ac019a9b 187 SUPERFAMILY SSF53955 36 185 4.64E-43 T 29-03-2018 IPR023346 Lysozyme-like domain CB4_RS03255 c84e7e3903c88ccc789e5eb488325e22 758 SUPERFAMILY SSF55383 630 674 1.05E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS03255 c84e7e3903c88ccc789e5eb488325e22 758 Gene3D G3DSA:3.30.457.10 734 758 3.0E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS03255 c84e7e3903c88ccc789e5eb488325e22 758 Gene3D G3DSA:3.30.457.10 676 733 6.8E-14 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS03255 c84e7e3903c88ccc789e5eb488325e22 758 Gene3D G3DSA:3.30.457.10 316 675 2.4E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS03255 c84e7e3903c88ccc789e5eb488325e22 758 Pfam PF07833 Copper amine oxidase N-terminal domain 658 753 6.9E-22 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS03255 c84e7e3903c88ccc789e5eb488325e22 758 Pfam PF07833 Copper amine oxidase N-terminal domain 605 673 1.7E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS03255 c84e7e3903c88ccc789e5eb488325e22 758 SUPERFAMILY SSF55383 677 749 8.24E-18 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS07660 deb4ca10092b7ce2fcf00fcd9cdb33a6 174 Pfam PF01202 Shikimate kinase 10 163 1.7E-41 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CB4_RS07660 deb4ca10092b7ce2fcf00fcd9cdb33a6 174 SUPERFAMILY SSF52540 2 162 8.26E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07660 deb4ca10092b7ce2fcf00fcd9cdb33a6 174 Hamap MF_00109 Shikimate kinase [aroK]. 1 166 25.472 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CB4_RS07660 deb4ca10092b7ce2fcf00fcd9cdb33a6 174 Gene3D G3DSA:3.40.50.300 1 166 1.8E-28 T 29-03-2018 CB4_RS07660 deb4ca10092b7ce2fcf00fcd9cdb33a6 174 PRINTS PR01100 Shikimate kinase family signature 75 84 7.2E-19 T 29-03-2018 CB4_RS07660 deb4ca10092b7ce2fcf00fcd9cdb33a6 174 PRINTS PR01100 Shikimate kinase family signature 56 64 7.2E-19 T 29-03-2018 CB4_RS07660 deb4ca10092b7ce2fcf00fcd9cdb33a6 174 PRINTS PR01100 Shikimate kinase family signature 4 19 7.2E-19 T 29-03-2018 CB4_RS07660 deb4ca10092b7ce2fcf00fcd9cdb33a6 174 PRINTS PR01100 Shikimate kinase family signature 96 113 7.2E-19 T 29-03-2018 CB4_RS07660 deb4ca10092b7ce2fcf00fcd9cdb33a6 174 PRINTS PR01100 Shikimate kinase family signature 28 41 7.2E-19 T 29-03-2018 CB4_RS09195 6196c1d37706d462b872c77e67b432dd 416 SMART SM00962 220 411 9.8E-62 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS09195 6196c1d37706d462b872c77e67b432dd 416 Pfam PF00448 SRP54-type protein, GTPase domain 223 410 1.1E-42 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CB4_RS09195 6196c1d37706d462b872c77e67b432dd 416 SMART SM00382 219 361 0.0063 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS09195 6196c1d37706d462b872c77e67b432dd 416 SUPERFAMILY SSF52540 220 411 4.64E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09195 6196c1d37706d462b872c77e67b432dd 416 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 307 3.5E-70 T 29-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 CB4_RS09195 6196c1d37706d462b872c77e67b432dd 416 Gene3D G3DSA:3.40.50.300 217 399 2.4E-22 T 29-03-2018 CB4_RS08730 e5ddae81d38f3f6db57d7449094b908f 532 SMART SM00857 3 152 2.6E-49 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS08730 e5ddae81d38f3f6db57d7449094b908f 532 Gene3D G3DSA:1.20.1000.10 139 489 2.1E-4 T 29-03-2018 CB4_RS08730 e5ddae81d38f3f6db57d7449094b908f 532 SUPERFAMILY SSF53041 1 152 4.05E-33 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS08730 e5ddae81d38f3f6db57d7449094b908f 532 Pfam PF07508 Recombinase 183 292 4.6E-15 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CB4_RS08730 e5ddae81d38f3f6db57d7449094b908f 532 Pfam PF13408 Recombinase zinc beta ribbon domain 305 368 4.8E-13 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain CB4_RS08730 e5ddae81d38f3f6db57d7449094b908f 532 Pfam PF00239 Resolvase, N terminal domain 3 152 1.2E-34 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS08730 e5ddae81d38f3f6db57d7449094b908f 532 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CB4_RS08730 e5ddae81d38f3f6db57d7449094b908f 532 Gene3D G3DSA:3.40.50.1390 2 138 6.2E-37 T 29-03-2018 CB4_RS18515 d402ff8dee1a1142c95fdb36ff924ec8 492 Gene3D G3DSA:3.30.1490.20 240 311 3.3E-10 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS18515 d402ff8dee1a1142c95fdb36ff924ec8 492 Pfam PF14398 YheC/D like ATP-grasp 212 465 1.8E-76 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CB4_RS18515 d402ff8dee1a1142c95fdb36ff924ec8 492 Gene3D G3DSA:3.30.470.20 312 450 1.1E-14 T 29-03-2018 CB4_RS18515 d402ff8dee1a1142c95fdb36ff924ec8 492 SUPERFAMILY SSF56059 230 439 4.42E-14 T 29-03-2018 CB4_RS13905 c7cbe13062f47a392a34a5ba9583509f 180 Pfam PF04234 CopC domain 22 114 2.0E-22 T 29-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CB4_RS13905 c7cbe13062f47a392a34a5ba9583509f 180 Gene3D G3DSA:2.60.40.1220 21 115 9.2E-23 T 29-03-2018 CB4_RS13905 c7cbe13062f47a392a34a5ba9583509f 180 SUPERFAMILY SSF81296 21 115 4.55E-19 T 29-03-2018 IPR014756 Immunoglobulin E-set CB4_RS14815 91d6f4ce9cec110caf29ac94d1ffb364 192 PIRSF PIRSF000847 1 191 1.6E-50 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CB4_RS14815 91d6f4ce9cec110caf29ac94d1ffb364 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CB4_RS14815 91d6f4ce9cec110caf29ac94d1ffb364 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 82 1.7E-16 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CB4_RS14815 91d6f4ce9cec110caf29ac94d1ffb364 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2 188 5.1E-55 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CB4_RS02675 81ec36d8cbb131dfb22bf50a7307f34a 445 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 16 422 3.5E-149 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CB4_RS02675 81ec36d8cbb131dfb22bf50a7307f34a 445 Pfam PF05525 Branched-chain amino acid transport protein 10 434 4.6E-157 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CB4_RS01285 d97aa1568361130f752c62772f5ce5b3 310 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 10 301 4.6E-95 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CB4_RS01285 d97aa1568361130f752c62772f5ce5b3 310 SUPERFAMILY SSF161098 22 295 4.8E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS01285 d97aa1568361130f752c62772f5ce5b3 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 298 1.8E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS01285 d97aa1568361130f752c62772f5ce5b3 310 Gene3D G3DSA:1.10.3720.10 3 296 3.0E-37 T 29-03-2018 CB4_RS13550 21ff7260ca30d353e5aef88c10585ae9 339 SUPERFAMILY SSF54001 160 293 2.1E-32 T 29-03-2018 CB4_RS13550 21ff7260ca30d353e5aef88c10585ae9 339 Pfam PF01841 Transglutaminase-like superfamily 167 273 1.1E-27 T 29-03-2018 IPR002931 Transglutaminase-like CB4_RS13550 21ff7260ca30d353e5aef88c10585ae9 339 SMART SM00460 206 275 2.6E-21 T 29-03-2018 IPR002931 Transglutaminase-like CB4_RS13550 21ff7260ca30d353e5aef88c10585ae9 339 Gene3D G3DSA:3.90.260.10 93 290 1.9E-13 T 29-03-2018 IPR002931 Transglutaminase-like CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 Gene3D G3DSA:3.40.50.720 1 261 8.8E-68 T 29-03-2018 CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 Pfam PF00106 short chain dehydrogenase 7 194 4.2E-58 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 7.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 PIRSF PIRSF000126 3 260 2.1E-52 T 29-03-2018 CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 SUPERFAMILY SSF51735 3 256 1.42E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 8.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 8.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 8.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17105 bfc7b68f0d06b2f324facc866e163ba6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS09335 16cca7f5feda1a0fa79234648fb7bae9 120 SUPERFAMILY SSF89919 1 111 5.63E-39 T 29-03-2018 IPR023799 Ribosome-binding factor A domain CB4_RS09335 16cca7f5feda1a0fa79234648fb7bae9 120 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 92 6.0E-29 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CB4_RS09335 16cca7f5feda1a0fa79234648fb7bae9 120 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 115 25.039 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CB4_RS09335 16cca7f5feda1a0fa79234648fb7bae9 120 Pfam PF02033 Ribosome-binding factor A 5 108 7.9E-36 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CB4_RS09335 16cca7f5feda1a0fa79234648fb7bae9 120 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 4 113 1.9E-37 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CB4_RS09335 16cca7f5feda1a0fa79234648fb7bae9 120 Gene3D G3DSA:3.30.300.20 3 115 1.1E-39 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CB4_RS09335 16cca7f5feda1a0fa79234648fb7bae9 120 ProSitePatterns PS01319 Ribosome-binding factor A signature. 74 95 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CB4_RS11510 3bb1a03b60714c977e8677aaae710b27 2902 Pfam PF10145 Phage-related minor tail protein 1596 1792 3.9E-9 T 29-03-2018 IPR010090 Phage tail tape measure protein CB4_RS19435 c7c7353cc2cc9aa644b703724611fc3a 162 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CB4_RS19435 c7c7353cc2cc9aa644b703724611fc3a 162 Pfam PF01066 CDP-alcohol phosphatidyltransferase 8 71 1.4E-14 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CB4_RS19435 c7c7353cc2cc9aa644b703724611fc3a 162 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 13 160 1.1E-31 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CB4_RS03645 4cf43c414a82815d180320e5a81ff266 275 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 4 266 18.404 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CB4_RS03645 4cf43c414a82815d180320e5a81ff266 275 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 7 261 1.5E-78 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CB4_RS03645 4cf43c414a82815d180320e5a81ff266 275 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 134 146 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CB4_RS03645 4cf43c414a82815d180320e5a81ff266 275 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 264 5.4E-77 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CB4_RS19360 f3fc469039a2eecaf4841193d8ef2033 67 Pfam PF13046 Protein of unknown function (DUF3906) 1 65 1.1E-16 T 29-03-2018 IPR024998 Protein of unknown function DUF3906 CB4_RS20495 80954cd01f2f9ca108c19ffb1cf81197 236 Gene3D G3DSA:3.30.420.40 1 138 3.3E-37 T 29-03-2018 CB4_RS20495 80954cd01f2f9ca108c19ffb1cf81197 236 Pfam PF00814 Glycoprotease family 32 205 1.8E-33 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20495 80954cd01f2f9ca108c19ffb1cf81197 236 SUPERFAMILY SSF53067 108 220 3.75E-17 T 29-03-2018 CB4_RS20495 80954cd01f2f9ca108c19ffb1cf81197 236 SUPERFAMILY SSF53067 1 103 2.72E-29 T 29-03-2018 CB4_RS20495 80954cd01f2f9ca108c19ffb1cf81197 236 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 222 5.9E-58 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CB4_RS12045 4250f199abd696b6e66f4eb476ebd085 499 Pfam PF02332 Methane/Phenol/Toluene Hydroxylase 22 250 8.0E-57 T 29-03-2018 IPR003430 Methane/phenol/toluene hydroxylase GO:0006725|GO:0055114 CB4_RS12045 4250f199abd696b6e66f4eb476ebd085 499 Gene3D G3DSA:1.10.620.20 1 498 2.6E-129 T 29-03-2018 CB4_RS12045 4250f199abd696b6e66f4eb476ebd085 499 Pfam PF04945 YHS domain 412 448 4.2E-12 T 29-03-2018 IPR007029 YHS domain CB4_RS12045 4250f199abd696b6e66f4eb476ebd085 499 SUPERFAMILY SSF47240 5 492 3.82E-123 T 29-03-2018 IPR009078 Ferritin-like superfamily CB4_RS07915 e8d4dc8291de64dc344687267000341c 233 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 4 115 9.3E-23 T 29-03-2018 IPR014245 Sporulation stage III, protein AF CB4_RS07915 e8d4dc8291de64dc344687267000341c 233 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 13 224 2.8E-34 T 29-03-2018 IPR014245 Sporulation stage III, protein AF CB4_RS15805 ea6814d780e6a1c35487b1d20e794298 267 Pfam PF02517 CAAX protease self-immunity 165 256 1.3E-16 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 Gene3D G3DSA:1.25.40.10 240 269 0.11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 SMART SM00028 104 137 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 SMART SM00028 306 339 43.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 SMART SM00028 203 236 0.0049 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 SMART SM00028 169 202 410.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 SMART SM00028 35 68 3.3E-6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 Gene3D G3DSA:1.25.40.10 155 239 6.4E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 Gene3D G3DSA:1.20.58.280 56 83 6.2E-8 T 29-03-2018 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 Pfam PF00515 Tetratricopeptide repeat 37 68 1.3E-7 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 Pfam PF14559 Tetratricopeptide repeat 179 236 1.4E-7 T 29-03-2018 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 Gene3D G3DSA:3.30.70.100 3 55 0.0059 T 29-03-2018 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 SUPERFAMILY SSF48452 170 341 4.1E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 Gene3D G3DSA:1.25.40.10 84 154 7.1E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 SUPERFAMILY SSF48452 34 140 2.35E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS03790 fc1a494f6367e8171b0baa796adb2145 580 Gene3D G3DSA:1.25.40.10 270 358 9.8E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS10530 0f1b9127081a85e7516c4ff0a00fbbac 86 Pfam PF04226 Transglycosylase associated protein 33 78 4.8E-12 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CB4_RS19195 bebfc83590c1202db38d3527433d648c 355 Pfam PF06081 Aromatic acid exporter family member 1 1 141 2.2E-37 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 CB4_RS18400 363ba68dcfe657c612e86d0ddbbd8be4 379 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 16 364 7.3E-100 T 29-03-2018 IPR014227 Sporulation integral membrane protein YtvI CB4_RS18400 363ba68dcfe657c612e86d0ddbbd8be4 379 Pfam PF01594 AI-2E family transporter 14 361 1.7E-59 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CB4_RS10000 2c344dbf792a0e154fd896b56ab094ad 448 SUPERFAMILY SSF56059 202 409 6.56E-17 T 29-03-2018 CB4_RS10000 2c344dbf792a0e154fd896b56ab094ad 448 Pfam PF14398 YheC/D like ATP-grasp 185 438 1.5E-62 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CB4_RS10000 2c344dbf792a0e154fd896b56ab094ad 448 Gene3D G3DSA:3.30.1490.20 213 284 7.4E-9 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS10000 2c344dbf792a0e154fd896b56ab094ad 448 Gene3D G3DSA:3.30.470.20 285 420 5.6E-10 T 29-03-2018 CB4_RS06700 77f89df6f3679fea847bd22a50d40142 244 SUPERFAMILY SSF88697 1 67 1.17E-15 T 29-03-2018 IPR015947 PUA-like domain CB4_RS06700 77f89df6f3679fea847bd22a50d40142 244 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 4 243 2.8E-62 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS06700 77f89df6f3679fea847bd22a50d40142 244 Pfam PF04452 RNA methyltransferase 16 240 3.0E-73 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS06700 77f89df6f3679fea847bd22a50d40142 244 Gene3D G3DSA:3.40.1280.10 1 244 4.8E-83 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CB4_RS06700 77f89df6f3679fea847bd22a50d40142 244 PIRSF PIRSF015601 1 244 6.2E-64 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS06700 77f89df6f3679fea847bd22a50d40142 244 SUPERFAMILY SSF75217 71 243 1.61E-51 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CB4_RS19255 8d93b9bf7c3c48fb8071ffad719a0f77 175 SUPERFAMILY SSF159234 7 169 9.42E-26 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CB4_RS19255 8d93b9bf7c3c48fb8071ffad719a0f77 175 Gene3D G3DSA:2.40.380.10 17 168 8.5E-29 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CB4_RS19255 8d93b9bf7c3c48fb8071ffad719a0f77 175 PIRSF PIRSF028345 1 175 2.1E-62 T 29-03-2018 IPR016882 Uncharacterised protein family UPF0374 CB4_RS19255 8d93b9bf7c3c48fb8071ffad719a0f77 175 Pfam PF04167 Protein of unknown function (DUF402) 58 122 2.4E-15 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CB4_RS00590 02f439fdcd2c173b51491cf719002c23 288 Gene3D G3DSA:3.40.50.720 1 288 9.6E-24 T 29-03-2018 CB4_RS00590 02f439fdcd2c173b51491cf719002c23 288 Pfam PF05368 NmrA-like family 2 221 7.4E-23 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CB4_RS00590 02f439fdcd2c173b51491cf719002c23 288 SUPERFAMILY SSF51735 2 252 4.51E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS11455 b397ccf271ca44e925de2701b9d78400 498 Gene3D G3DSA:1.20.5.400 317 428 3.6E-4 T 29-03-2018 CB4_RS10495 fdbff7d560161b673d7a313a1b38f793 172 SUPERFAMILY SSF141259 16 80 4.97E-15 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS10495 fdbff7d560161b673d7a313a1b38f793 172 Pfam PF02559 CarD-like/TRCF domain 16 124 8.5E-19 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS10495 fdbff7d560161b673d7a313a1b38f793 172 SMART SM01058 15 125 7.6E-32 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS16205 4f0d0b104fbefc6abe89fd6df10832b7 142 SUPERFAMILY SSF55874 22 130 3.27E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16205 4f0d0b104fbefc6abe89fd6df10832b7 142 Gene3D G3DSA:3.30.565.10 1 140 6.6E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16205 4f0d0b104fbefc6abe89fd6df10832b7 142 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 132 8.7E-60 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CB4_RS16205 4f0d0b104fbefc6abe89fd6df10832b7 142 SMART SM00387 31 136 1.1E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16205 4f0d0b104fbefc6abe89fd6df10832b7 142 Pfam PF13581 Histidine kinase-like ATPase domain 5 132 3.0E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16205 4f0d0b104fbefc6abe89fd6df10832b7 142 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 136 32.272 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CB4_RS14395 c4bbb4bac5434f313bc962df89af14ef 219 SUPERFAMILY SSF161098 13 208 4.97E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS14395 c4bbb4bac5434f313bc962df89af14ef 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 112 1.3E-24 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CB4_RS14395 c4bbb4bac5434f313bc962df89af14ef 219 Gene3D G3DSA:1.10.3720.10 4 219 2.5E-41 T 29-03-2018 CB4_RS14395 c4bbb4bac5434f313bc962df89af14ef 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 217 2.6E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS01695 054e36988b0fa3a990bf5e5f62cf0592 399 Pfam PF12698 ABC-2 family transporter protein 25 375 1.8E-43 T 29-03-2018 CB4_RS01695 054e36988b0fa3a990bf5e5f62cf0592 399 Gene3D G3DSA:3.40.1710.10 42 202 2.5E-29 T 29-03-2018 CB4_RS01635 e98e70f07846a6d1e96edf05a43c593b 305 Pfam PF02517 CAAX protease self-immunity 210 295 4.8E-19 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CB4_RS16925 f9140a3e2b72ecdd475bd36bd06e7db3 171 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 142 2.1E-50 T 29-03-2018 IPR014229 Sporulation protein YtfJ CB4_RS16925 f9140a3e2b72ecdd475bd36bd06e7db3 171 PIRSF PIRSF021377 1 167 3.2E-57 T 29-03-2018 IPR014229 Sporulation protein YtfJ CB4_RS16925 f9140a3e2b72ecdd475bd36bd06e7db3 171 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 134 3.9E-28 T 29-03-2018 IPR014229 Sporulation protein YtfJ CB4_RS14585 54d775eb07d71a808e1e3dc5e4d4f1e8 152 SUPERFAMILY SSF109854 6 145 1.63E-21 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CB4_RS14585 54d775eb07d71a808e1e3dc5e4d4f1e8 152 Gene3D G3DSA:1.20.120.450 1 152 1.3E-15 T 29-03-2018 CB4_RS14585 54d775eb07d71a808e1e3dc5e4d4f1e8 152 Pfam PF05163 DinB family 3 146 1.2E-18 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 1.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.7E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 3.7E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.7E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 3.7E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 3.7E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.7E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 SUPERFAMILY SSF51735 1 247 6.58E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 Pfam PF00106 short chain dehydrogenase 2 183 2.0E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS20100 be59190ce542c95573b384f39e9ebb04 272 Gene3D G3DSA:3.40.50.720 1 271 2.1E-56 T 29-03-2018 CB4_RS14450 8c7eb802dd4329a72ad11a30eb9aa73c 262 Gene3D G3DSA:3.30.565.10 59 251 1.1E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS14450 8c7eb802dd4329a72ad11a30eb9aa73c 262 SMART SM00387 142 253 3.8E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS14450 8c7eb802dd4329a72ad11a30eb9aa73c 262 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 143 251 9.5E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS14450 8c7eb802dd4329a72ad11a30eb9aa73c 262 PRINTS PR00344 Bacterial sensor protein C-terminal signature 179 193 2.5E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS14450 8c7eb802dd4329a72ad11a30eb9aa73c 262 PRINTS PR00344 Bacterial sensor protein C-terminal signature 197 207 2.5E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS14450 8c7eb802dd4329a72ad11a30eb9aa73c 262 PRINTS PR00344 Bacterial sensor protein C-terminal signature 213 231 2.5E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS14450 8c7eb802dd4329a72ad11a30eb9aa73c 262 SUPERFAMILY SSF55874 90 254 3.93E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS02020 b43696b418d97f51c916b505ee700130 653 Pfam PF02272 DHHA1 domain 515 643 7.1E-11 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CB4_RS02020 b43696b418d97f51c916b505ee700130 653 Gene3D G3DSA:3.30.70.270 171 299 1.8E-4 T 29-03-2018 CB4_RS02020 b43696b418d97f51c916b505ee700130 653 PIRSF PIRSF026583 1 652 9.5E-241 T 29-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CB4_RS02020 b43696b418d97f51c916b505ee700130 653 Pfam PF13188 PAS domain 80 128 1.2E-4 T 29-03-2018 IPR000014 PAS domain CB4_RS02020 b43696b418d97f51c916b505ee700130 653 Gene3D G3DSA:3.90.1640.10 316 533 2.1E-45 T 29-03-2018 CB4_RS02020 b43696b418d97f51c916b505ee700130 653 SMART SM00267 132 299 3.7E-4 T 29-03-2018 IPR000160 GGDEF domain CB4_RS02020 b43696b418d97f51c916b505ee700130 653 Pfam PF01368 DHH family 339 493 3.1E-20 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CB4_RS02020 b43696b418d97f51c916b505ee700130 653 SUPERFAMILY SSF64182 337 639 8.89E-67 T 29-03-2018 CB4_RS02020 b43696b418d97f51c916b505ee700130 653 Gene3D G3DSA:3.30.450.20 52 170 8.8E-5 T 29-03-2018 CB4_RS08010 d9a0ae8a5c9f336475ddba95ae11771f 440 SUPERFAMILY SSF50156 146 206 4.99E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS08010 d9a0ae8a5c9f336475ddba95ae11771f 440 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 5 427 9.4E-158 T 29-03-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B CB4_RS08010 d9a0ae8a5c9f336475ddba95ae11771f 440 SMART SM00228 128 197 9.7E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS08010 d9a0ae8a5c9f336475ddba95ae11771f 440 Gene3D G3DSA:2.30.42.10 124 228 4.5E-15 T 29-03-2018 CB4_RS08010 d9a0ae8a5c9f336475ddba95ae11771f 440 Gene3D G3DSA:2.40.10.10 320 423 0.003 T 29-03-2018 CB4_RS08010 d9a0ae8a5c9f336475ddba95ae11771f 440 Pfam PF05580 SpoIVB peptidase S55 214 422 1.8E-85 T 29-03-2018 IPR008763 Peptidase S55, SpoIVB CB4_RS08010 d9a0ae8a5c9f336475ddba95ae11771f 440 Pfam PF13180 PDZ domain 145 203 7.1E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS08010 d9a0ae8a5c9f336475ddba95ae11771f 440 SUPERFAMILY SSF50494 355 418 9.44E-5 T 29-03-2018 IPR009003 Peptidase S1, PA clan CB4_RS18915 b162d41c51a2e3a5c946637f8bfcbcae 154 SUPERFAMILY SSF75217 3 153 1.77E-42 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CB4_RS18915 b162d41c51a2e3a5c946637f8bfcbcae 154 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 2 153 1.9E-62 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CB4_RS18915 b162d41c51a2e3a5c946637f8bfcbcae 154 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 151 33.794 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CB4_RS18915 b162d41c51a2e3a5c946637f8bfcbcae 154 Gene3D G3DSA:3.40.1280.10 1 154 3.2E-36 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CB4_RS18915 b162d41c51a2e3a5c946637f8bfcbcae 154 Pfam PF00588 SpoU rRNA Methylase family 3 142 1.1E-31 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CB4_RS18915 b162d41c51a2e3a5c946637f8bfcbcae 154 PIRSF PIRSF029256 2 154 6.5E-64 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 445 3.8E-186 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 7.1E-44 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 SUPERFAMILY SSF55957 360 448 6.93E-25 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 255 3.2E-18 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 SUPERFAMILY SSF53738 259 367 5.1E-32 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 Gene3D G3DSA:3.40.120.10 265 376 1.9E-31 T 29-03-2018 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 447 45.528 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 443 1.5E-17 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 6.9E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 6.9E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 6.9E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 371 2.6E-33 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 Gene3D G3DSA:3.40.120.10 166 264 1.8E-26 T 29-03-2018 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 Gene3D G3DSA:3.30.310.50 377 449 4.8E-23 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 Gene3D G3DSA:3.40.120.10 2 165 6.2E-46 T 29-03-2018 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 SUPERFAMILY SSF53738 3 182 1.37E-49 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS00610 1e3e2e970cfa65009257f1628750a0f7 449 SUPERFAMILY SSF53738 159 257 2.51E-27 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CB4_RS07845 dc5e5d138a13e171b3589edded1b533d 141 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 126 1.5E-17 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CB4_RS07845 dc5e5d138a13e171b3589edded1b533d 141 Gene3D G3DSA:1.10.60.10 75 136 2.1E-19 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CB4_RS07845 dc5e5d138a13e171b3589edded1b533d 141 SUPERFAMILY SSF46785 3 62 2.35E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07845 dc5e5d138a13e171b3589edded1b533d 141 SMART SM00529 24 126 4.3E-39 T 29-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CB4_RS07845 dc5e5d138a13e171b3589edded1b533d 141 Gene3D G3DSA:1.10.10.10 1 72 6.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07845 dc5e5d138a13e171b3589edded1b533d 141 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 60 2.0E-26 T 29-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CB4_RS07845 dc5e5d138a13e171b3589edded1b533d 141 SUPERFAMILY SSF47979 63 128 7.85E-17 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CB4_RS07845 dc5e5d138a13e171b3589edded1b533d 141 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 39.217 T 29-03-2018 IPR022897 Transcription regulator MntR CB4_RS13995 46e92f63e211697031ba294bf1205b41 807 Gene3D G3DSA:3.20.20.70 1 165 9.7E-11 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS13995 46e92f63e211697031ba294bf1205b41 807 Gene3D G3DSA:3.20.20.70 418 664 0.0065 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS13995 46e92f63e211697031ba294bf1205b41 807 Pfam PF12392 Collagenase 381 501 9.0E-23 T 29-03-2018 IPR020988 Peptidase U32, collagenase CB4_RS13995 46e92f63e211697031ba294bf1205b41 807 Pfam PF01136 Peptidase family U32 60 285 3.1E-85 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CB4_RS13995 46e92f63e211697031ba294bf1205b41 807 Pfam PF01136 Peptidase family U32 592 786 1.6E-17 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CB4_RS13995 46e92f63e211697031ba294bf1205b41 807 SUPERFAMILY SSF51412 45 138 8.33E-5 T 29-03-2018 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 58 706 8.9E-229 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 Pfam PF08206 Ribonuclease B OB domain 71 129 5.5E-20 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 Pfam PF08206 Ribonuclease B OB domain 144 199 2.0E-8 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 SUPERFAMILY SSF50249 206 624 1.48E-147 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 SUPERFAMILY SSF50249 123 223 3.82E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 Pfam PF00575 S1 RNA binding domain 626 704 4.2E-13 T 29-03-2018 IPR003029 S1 domain GO:0003676 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 SUPERFAMILY SSF50249 627 705 5.59E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 SMART SM00357 70 130 3.1E-11 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 SMART SM00357 135 200 3.5E-4 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 Gene3D G3DSA:2.40.50.140 63 135 0.0028 T 29-03-2018 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 Gene3D G3DSA:2.40.50.140 136 281 0.024 T 29-03-2018 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 TIGRFAM TIGR02063 RNase_R: ribonuclease R 2 706 5.9E-280 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 SMART SM00955 246 576 2.0E-178 T 29-03-2018 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 SUPERFAMILY SSF50249 51 132 2.06E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 Gene3D G3DSA:1.10.10.10 4 60 7.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 Hamap MF_01895 Ribonuclease R [rnr]. 22 706 60.139 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 Gene3D G3DSA:2.40.50.140 623 707 2.4E-21 T 29-03-2018 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 SMART SM00316 624 706 5.1E-14 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 ProSitePatterns PS01175 Ribonuclease II family signature. 543 567 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site CB4_RS03900 b570162739a9ce5ccf2eb7a3941d76e7 774 Pfam PF00773 RNB domain 246 575 2.2E-116 T 29-03-2018 CB4_RS05995 8ecee8b35c529a724b2f1e2b54701aad 780 Pfam PF02272 DHHA1 domain 313 436 5.8E-22 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CB4_RS05995 8ecee8b35c529a724b2f1e2b54701aad 780 Gene3D G3DSA:3.90.1640.10 64 237 4.9E-24 T 29-03-2018 CB4_RS05995 8ecee8b35c529a724b2f1e2b54701aad 780 SUPERFAMILY SSF64182 57 450 4.45E-122 T 29-03-2018 CB4_RS05995 8ecee8b35c529a724b2f1e2b54701aad 780 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 560 8.9E-181 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CB4_RS05995 8ecee8b35c529a724b2f1e2b54701aad 780 Pfam PF01368 DHH family 83 225 2.2E-12 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CB4_RS05995 8ecee8b35c529a724b2f1e2b54701aad 780 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 566 759 1.3E-36 T 29-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal CB4_RS05995 8ecee8b35c529a724b2f1e2b54701aad 780 Gene3D G3DSA:3.40.50.10260 296 457 6.9E-4 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 SUPERFAMILY SSF53448 741 1029 1.23E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 Pfam PF01522 Polysaccharide deacetylase 480 588 1.7E-30 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 Gene3D G3DSA:3.20.20.370 453 686 1.8E-57 T 29-03-2018 CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 Pfam PF00704 Glycosyl hydrolases family 18 115 400 3.7E-21 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 Gene3D G3DSA:3.90.550.10 725 996 2.8E-68 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 SUPERFAMILY SSF88713 472 678 2.13E-59 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 SMART SM00636 112 401 3.7E-11 T 29-03-2018 IPR011583 Chitinase II GO:0008061 CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 Pfam PF13641 Glycosyltransferase like family 2 753 975 4.6E-39 T 29-03-2018 CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 Gene3D G3DSA:3.20.20.80 72 425 8.7E-46 T 29-03-2018 CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 SUPERFAMILY SSF51445 112 317 1.61E-34 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CB4_RS06205 119957ecb278ac1b51af17ea254c5450 1107 SUPERFAMILY SSF51445 373 419 1.61E-34 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CB4_RS16405 c42ed8ab38adca5f70970f2cf453abde 227 SUPERFAMILY SSF53448 4 220 8.45E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS16405 c42ed8ab38adca5f70970f2cf453abde 227 Pfam PF00535 Glycosyl transferase family 2 6 126 1.3E-24 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CB4_RS16405 c42ed8ab38adca5f70970f2cf453abde 227 Gene3D G3DSA:3.90.550.10 2 226 6.4E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS10830 4e4d0148fe3926d1925d1266f041ae2d 82 SMART SM00966 8 51 1.8E-7 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS10830 4e4d0148fe3926d1925d1266f041ae2d 82 Gene3D G3DSA:2.10.260.10 1 48 5.0E-17 T 29-03-2018 CB4_RS10830 4e4d0148fe3926d1925d1266f041ae2d 82 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 2.9E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS10830 4e4d0148fe3926d1925d1266f041ae2d 82 SUPERFAMILY SSF89447 1 53 4.58E-15 T 29-03-2018 CB4_RS10830 4e4d0148fe3926d1925d1266f041ae2d 82 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 1.2E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS12755 5a058e7ab68b13accf570cf274b5bdd9 202 Gene3D G3DSA:3.40.50.150 2 178 4.4E-19 T 29-03-2018 CB4_RS12755 5a058e7ab68b13accf570cf274b5bdd9 202 SUPERFAMILY SSF53335 6 201 5.23E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS12755 5a058e7ab68b13accf570cf274b5bdd9 202 Pfam PF13649 Methyltransferase domain 40 131 1.1E-11 T 29-03-2018 CB4_RS18820 acf2ec9745683eb63fbb91754d9da195 126 Gene3D G3DSA:2.40.70.10 1 119 4.1E-15 T 29-03-2018 IPR021109 Aspartic peptidase domain CB4_RS18820 acf2ec9745683eb63fbb91754d9da195 126 SUPERFAMILY SSF50630 15 117 3.03E-11 T 29-03-2018 IPR021109 Aspartic peptidase domain CB4_RS18820 acf2ec9745683eb63fbb91754d9da195 126 Pfam PF13650 Aspartyl protease 15 108 1.6E-12 T 29-03-2018 CB4_RS04380 64466ab4c8d9ea6ef19e5640a27fa576 93 Gene3D G3DSA:1.20.1260.10 16 93 1.0E-5 T 29-03-2018 IPR012347 Ferritin-related CB4_RS15095 6c3a2538840d409d156ae5525a517028 357 Pfam PF00155 Aminotransferase class I and II 29 349 7.5E-55 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS15095 6c3a2538840d409d156ae5525a517028 357 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 352 1.9E-108 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CB4_RS15095 6c3a2538840d409d156ae5525a517028 357 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 354 59.995 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CB4_RS15095 6c3a2538840d409d156ae5525a517028 357 Gene3D G3DSA:3.90.1150.10 250 349 1.5E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS15095 6c3a2538840d409d156ae5525a517028 357 SUPERFAMILY SSF53383 14 354 5.91E-79 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS15095 6c3a2538840d409d156ae5525a517028 357 Gene3D G3DSA:3.40.640.10 44 249 1.2E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS08915 88e5f69d8c5371532d3d43b3d3e2017b 87 Pfam PF05135 Phage gp6-like head-tail connector protein 6 82 9.4E-8 T 29-03-2018 IPR021146 Phage gp6-like head-tail connector protein CB4_RS08915 88e5f69d8c5371532d3d43b3d3e2017b 87 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 6 84 1.7E-10 T 29-03-2018 IPR006450 Phage protein of unkonwn function CB4_RS06615 22e7655228604823a49ec088f90870e4 180 Gene3D G3DSA:1.10.1740.10 1 100 2.0E-23 T 29-03-2018 CB4_RS06615 22e7655228604823a49ec088f90870e4 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 172 1.3E-28 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06615 22e7655228604823a49ec088f90870e4 180 Pfam PF08281 Sigma-70, region 4 117 168 3.7E-20 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06615 22e7655228604823a49ec088f90870e4 180 SUPERFAMILY SSF88659 104 173 7.66E-19 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06615 22e7655228604823a49ec088f90870e4 180 SUPERFAMILY SSF88946 3 101 8.95E-25 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06615 22e7655228604823a49ec088f90870e4 180 Pfam PF04542 Sigma-70 region 2 22 87 6.0E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06615 22e7655228604823a49ec088f90870e4 180 Gene3D G3DSA:1.10.10.10 101 178 3.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 SMART SM00847 389 514 2.4E-17 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 Gene3D G3DSA:3.40.50.300 3 163 2.0E-19 T 29-03-2018 CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 SMART SM00487 2 187 1.3E-12 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 Pfam PF08482 ATP-dependent helicase C-terminal 682 814 3.4E-53 T 29-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 SUPERFAMILY SSF52540 16 431 2.76E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 Gene3D G3DSA:3.40.50.300 181 350 5.7E-48 T 29-03-2018 CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 PIRSF PIRSF005496 1 827 0.0 T 29-03-2018 CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 SMART SM00490 227 330 4.0E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 4 826 0.0 T 29-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 Pfam PF00271 Helicase conserved C-terminal domain 205 329 9.4E-15 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 Pfam PF00270 DEAD/DEAH box helicase 19 165 3.3E-6 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS02275 3a08fbdce20052afb6811030105e006a 827 Pfam PF04408 Helicase associated domain (HA2) 390 499 3.7E-14 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 CB4_RS01845 014bcad59e0af20b8c6daeba39fc33b3 294 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 4 294 52.767 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CB4_RS01845 014bcad59e0af20b8c6daeba39fc33b3 294 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 9 294 6.0E-154 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CB4_RS01845 014bcad59e0af20b8c6daeba39fc33b3 294 ProSitePatterns PS01235 PdxS/SNZ family signature. 205 223 - T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CB4_RS01845 014bcad59e0af20b8c6daeba39fc33b3 294 SUPERFAMILY SSF51366 18 269 1.13E-65 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CB4_RS01845 014bcad59e0af20b8c6daeba39fc33b3 294 Pfam PF01680 SOR/SNZ family 7 212 2.5E-106 T 29-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CB4_RS01845 014bcad59e0af20b8c6daeba39fc33b3 294 Gene3D G3DSA:3.20.20.70 18 271 1.2E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS01845 014bcad59e0af20b8c6daeba39fc33b3 294 PIRSF PIRSF029271 1 294 8.8E-151 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CB4_RS09125 63d5e7840aeab081daa94cb48f5b3636 162 Pfam PF03963 Flagellar hook capping protein - N-terminal region 11 74 4.3E-22 T 29-03-2018 IPR005648 Flagellar hook capping protein CB4_RS09010 6f6e2e2ef144be11a880c13c39eac3de 59 Gene3D G3DSA:2.20.28.20 3 29 6.7E-4 T 29-03-2018 CB4_RS18170 0c0b9ef3c1135e9f35ca1c5322f6402d 131 Gene3D G3DSA:3.40.1650.10 1 131 1.3E-40 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CB4_RS18170 0c0b9ef3c1135e9f35ca1c5322f6402d 131 Pfam PF05025 RbsD / FucU transport protein family 1 130 2.5E-49 T 29-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CB4_RS18170 0c0b9ef3c1135e9f35ca1c5322f6402d 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 33.121 T 29-03-2018 IPR023064 D-ribose pyranase GO:0016872 CB4_RS18170 0c0b9ef3c1135e9f35ca1c5322f6402d 131 SUPERFAMILY SSF102546 1 131 2.75E-46 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CB4_RS04715 ffa21f688ac089757654f458cd71c778 429 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 145 420 8.7E-72 T 29-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CB4_RS04715 ffa21f688ac089757654f458cd71c778 429 Pfam PF01458 Uncharacterized protein family (UPF0051) 179 403 5.5E-61 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CB4_RS04715 ffa21f688ac089757654f458cd71c778 429 SUPERFAMILY SSF101960 17 428 5.36E-106 T 29-03-2018 CB4_RS14790 3cc57f27847b6eee5616881296679685 184 Pfam PF02632 BioY family 22 169 4.9E-39 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CB4_RS14790 3cc57f27847b6eee5616881296679685 184 PIRSF PIRSF016661 1 176 4.7E-45 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CB4_RS01220 1f1ff2606ac2bc5b783dcd070605388a 160 Pfam PF02542 YgbB family 2 156 4.4E-68 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CB4_RS01220 1f1ff2606ac2bc5b783dcd070605388a 160 Gene3D G3DSA:3.30.1330.50 1 159 2.0E-75 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CB4_RS01220 1f1ff2606ac2bc5b783dcd070605388a 160 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 156 2.5E-71 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CB4_RS01220 1f1ff2606ac2bc5b783dcd070605388a 160 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CB4_RS01220 1f1ff2606ac2bc5b783dcd070605388a 160 SUPERFAMILY SSF69765 1 157 5.49E-68 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CB4_RS01220 1f1ff2606ac2bc5b783dcd070605388a 160 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 37.773 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CB4_RS12005 59970610da8a24f38e7295413f855405 461 Pfam PF00324 Amino acid permease 15 449 1.5E-112 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CB4_RS12005 59970610da8a24f38e7295413f855405 461 PIRSF PIRSF006060 1 460 1.1E-74 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS05460 58cea585b58120ea5b80f2a911e552e0 529 Pfam PF03023 MviN-like protein 31 483 2.8E-78 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS05460 58cea585b58120ea5b80f2a911e552e0 529 PIRSF PIRSF002869 1 518 6.3E-103 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS05460 58cea585b58120ea5b80f2a911e552e0 529 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 5 477 15.522 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS05460 58cea585b58120ea5b80f2a911e552e0 529 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 5 512 5.1E-90 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS05460 58cea585b58120ea5b80f2a911e552e0 529 PRINTS PR01806 Virulence factor MviN signature 35 54 2.0E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS05460 58cea585b58120ea5b80f2a911e552e0 529 PRINTS PR01806 Virulence factor MviN signature 419 436 2.0E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS05460 58cea585b58120ea5b80f2a911e552e0 529 PRINTS PR01806 Virulence factor MviN signature 367 386 2.0E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS05460 58cea585b58120ea5b80f2a911e552e0 529 PRINTS PR01806 Virulence factor MviN signature 142 166 2.0E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS05460 58cea585b58120ea5b80f2a911e552e0 529 PRINTS PR01806 Virulence factor MviN signature 266 292 2.0E-21 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS20445 1b12510bccf2881abdda5b7c279a1d87 462 Gene3D G3DSA:1.10.3860.10 21 450 1.3E-85 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS20445 1b12510bccf2881abdda5b7c279a1d87 462 Pfam PF00375 Sodium:dicarboxylate symporter family 32 442 7.6E-99 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS20445 1b12510bccf2881abdda5b7c279a1d87 462 SUPERFAMILY SSF118215 30 442 1.24E-91 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS20445 1b12510bccf2881abdda5b7c279a1d87 462 PRINTS PR00173 Glutamate-aspartate symporter signature 97 122 4.7E-10 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS20445 1b12510bccf2881abdda5b7c279a1d87 462 PRINTS PR00173 Glutamate-aspartate symporter signature 233 252 4.7E-10 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS20445 1b12510bccf2881abdda5b7c279a1d87 462 PRINTS PR00173 Glutamate-aspartate symporter signature 397 417 4.7E-10 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS20445 1b12510bccf2881abdda5b7c279a1d87 462 PRINTS PR00173 Glutamate-aspartate symporter signature 370 389 4.7E-10 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS20445 1b12510bccf2881abdda5b7c279a1d87 462 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 4.7E-10 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS13710 0d16487de3ac91e35085e9f2bb314d2d 369 Gene3D G3DSA:2.40.50.100 244 354 0.36 T 29-03-2018 CB4_RS13710 0d16487de3ac91e35085e9f2bb314d2d 369 Pfam PF08402 TOBE domain 278 346 3.2E-9 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CB4_RS13710 0d16487de3ac91e35085e9f2bb314d2d 369 SUPERFAMILY SSF50331 241 346 5.44E-13 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CB4_RS13710 0d16487de3ac91e35085e9f2bb314d2d 369 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 39 292 3.3E-107 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CB4_RS13710 0d16487de3ac91e35085e9f2bb314d2d 369 SMART SM00382 33 216 4.4E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13710 0d16487de3ac91e35085e9f2bb314d2d 369 Pfam PF00005 ABC transporter 24 166 4.2E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS13710 0d16487de3ac91e35085e9f2bb314d2d 369 Gene3D G3DSA:3.40.50.300 3 243 4.1E-77 T 29-03-2018 CB4_RS13710 0d16487de3ac91e35085e9f2bb314d2d 369 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS13710 0d16487de3ac91e35085e9f2bb314d2d 369 SUPERFAMILY SSF52540 7 248 1.02E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS16380 b0a73e96dad015219493700d9448c897 330 Gene3D G3DSA:3.40.50.970 2 330 3.2E-83 T 29-03-2018 CB4_RS16380 b0a73e96dad015219493700d9448c897 330 SUPERFAMILY SSF52518 8 330 6.14E-102 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS16380 b0a73e96dad015219493700d9448c897 330 Pfam PF00676 Dehydrogenase E1 component 22 320 1.9E-97 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CB4_RS08785 313e70a0a97461a778d91489658c9f09 173 Pfam PF01381 Helix-turn-helix 3 51 4.2E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS08785 313e70a0a97461a778d91489658c9f09 173 Gene3D G3DSA:1.10.260.40 1 169 5.8E-8 T 29-03-2018 CB4_RS08785 313e70a0a97461a778d91489658c9f09 173 SUPERFAMILY SSF47413 3 51 9.92E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS08785 313e70a0a97461a778d91489658c9f09 173 SMART SM00530 1 56 6.1E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS00900 783a7c2f1b6e3bc36e46607aaa37cecf 102 Gene3D G3DSA:2.30.30.30 1 91 4.4E-37 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CB4_RS00900 783a7c2f1b6e3bc36e46607aaa37cecf 102 SUPERFAMILY SSF50104 1 100 2.48E-38 T 29-03-2018 IPR008991 Translation protein SH3-like domain CB4_RS00900 783a7c2f1b6e3bc36e46607aaa37cecf 102 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 1.8E-30 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00900 783a7c2f1b6e3bc36e46607aaa37cecf 102 Pfam PF00467 KOW motif 6 36 3.5E-8 T 29-03-2018 IPR005824 KOW CB4_RS00900 783a7c2f1b6e3bc36e46607aaa37cecf 102 SMART SM00739 2 29 6.7E-5 T 29-03-2018 IPR005824 KOW CB4_RS00900 783a7c2f1b6e3bc36e46607aaa37cecf 102 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 101 1.2E-40 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00900 783a7c2f1b6e3bc36e46607aaa37cecf 102 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 21.609 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00900 783a7c2f1b6e3bc36e46607aaa37cecf 102 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS03350 7568901cda42299d1d82463325cdb523 391 Pfam PF07730 Histidine kinase 180 248 5.3E-14 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CB4_RS03350 7568901cda42299d1d82463325cdb523 391 Pfam PF05384 Sensor protein DegS 12 170 1.5E-52 T 29-03-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 CB4_RS03350 7568901cda42299d1d82463325cdb523 391 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 379 7.6E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS03350 7568901cda42299d1d82463325cdb523 391 SMART SM00387 286 380 1.3E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS03350 7568901cda42299d1d82463325cdb523 391 Gene3D G3DSA:3.30.565.10 245 386 2.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS03350 7568901cda42299d1d82463325cdb523 391 SUPERFAMILY SSF55874 252 378 1.44E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS03350 7568901cda42299d1d82463325cdb523 391 PIRSF PIRSF003169 1 384 4.0E-138 T 29-03-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 CB4_RS16300 698ce0666cc8c02c6d5771ede1217bf4 87 Pfam PF14004 Protein of unknown function (DUF4227) 15 87 2.1E-17 T 29-03-2018 IPR025321 Protein of unknown function DUF4227 CB4_RS02900 39ffc2838c01d377ee9bfd85a7c95f55 147 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 144 4.4E-56 T 29-03-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 CB4_RS02900 39ffc2838c01d377ee9bfd85a7c95f55 147 Gene3D G3DSA:3.40.1400.10 1 147 4.3E-71 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CB4_RS02900 39ffc2838c01d377ee9bfd85a7c95f55 147 SUPERFAMILY SSF89623 1 144 1.14E-61 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CB4_RS02900 39ffc2838c01d377ee9bfd85a7c95f55 147 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 4.5E-62 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CB4_RS02900 39ffc2838c01d377ee9bfd85a7c95f55 147 PIRSF PIRSF005384 1 147 1.3E-59 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CB4_RS02900 39ffc2838c01d377ee9bfd85a7c95f55 147 Pfam PF02502 Ribose/Galactose Isomerase 3 140 1.2E-59 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CB4_RS12450 f591b3ef112db319821b68fb89c0260b 367 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 244 316 2.4E-14 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS12450 f591b3ef112db319821b68fb89c0260b 367 Pfam PF01385 Probable transposase 166 275 7.1E-25 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS12450 f591b3ef112db319821b68fb89c0260b 367 Gene3D G3DSA:1.20.1270.60 74 299 2.7E-4 T 29-03-2018 CB4_RS12450 f591b3ef112db319821b68fb89c0260b 367 Pfam PF07282 Putative transposase DNA-binding domain 289 359 3.1E-23 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS12450 f591b3ef112db319821b68fb89c0260b 367 Pfam PF12323 Helix-turn-helix domain 4 47 5.9E-19 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CB4_RS16160 1e5e671e79dbe2983b3d14a07a183b38 611 SUPERFAMILY SSF143968 506 598 6.02E-8 T 29-03-2018 CB4_RS16160 1e5e671e79dbe2983b3d14a07a183b38 611 Gene3D G3DSA:3.40.1670.10 469 584 2.2E-16 T 29-03-2018 CB4_RS16160 1e5e671e79dbe2983b3d14a07a183b38 611 Gene3D G3DSA:3.40.1670.10 316 468 7.7E-35 T 29-03-2018 CB4_RS16160 1e5e671e79dbe2983b3d14a07a183b38 611 SUPERFAMILY SSF50475 2 315 4.71E-89 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS16160 1e5e671e79dbe2983b3d14a07a183b38 611 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 433 5.0E-117 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CB4_RS16160 1e5e671e79dbe2983b3d14a07a183b38 611 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 7 452 2.6E-79 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CB4_RS16160 1e5e671e79dbe2983b3d14a07a183b38 611 SUPERFAMILY SSF143968 316 468 5.1E-24 T 29-03-2018 CB4_RS09205 58ac2c5d68f54ffd88f3a0cbdd3c49a0 195 SUPERFAMILY SSF52172 2 111 9.11E-28 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS09205 58ac2c5d68f54ffd88f3a0cbdd3c49a0 195 SMART SM00448 4 119 2.7E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS09205 58ac2c5d68f54ffd88f3a0cbdd3c49a0 195 Gene3D G3DSA:3.40.50.2300 1 186 2.2E-30 T 29-03-2018 CB4_RS09205 58ac2c5d68f54ffd88f3a0cbdd3c49a0 195 Pfam PF00072 Response regulator receiver domain 7 111 2.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS11990 b27ff576db6388857d5e697234fb1daa 467 Gene3D G3DSA:1.20.120.30 400 463 0.35 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CB4_RS11990 b27ff576db6388857d5e697234fb1daa 467 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 178 205 3.3E-17 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS11990 b27ff576db6388857d5e697234fb1daa 467 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 207 236 3.3E-17 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS11990 b27ff576db6388857d5e697234fb1daa 467 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 101 130 3.3E-17 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS11990 b27ff576db6388857d5e697234fb1daa 467 Pfam PF13682 Chemoreceptor zinc-binding domain 357 423 1.1E-13 T 29-03-2018 IPR025991 Chemoreceptor zinc-binding domain CB4_RS11990 b27ff576db6388857d5e697234fb1daa 467 Gene3D G3DSA:1.10.287.950 13 123 0.002 T 29-03-2018 CB4_RS11990 b27ff576db6388857d5e697234fb1daa 467 Gene3D G3DSA:1.10.287.950 124 343 7.3E-49 T 29-03-2018 CB4_RS11990 b27ff576db6388857d5e697234fb1daa 467 SMART SM00283 80 341 3.1E-60 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS11990 b27ff576db6388857d5e697234fb1daa 467 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 155 309 2.3E-39 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS11990 b27ff576db6388857d5e697234fb1daa 467 SUPERFAMILY SSF58104 33 341 6.15E-64 T 29-03-2018 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 SUPERFAMILY SSF82693 564 661 7.5E-15 T 29-03-2018 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 Gene3D G3DSA:1.20.1640.10 265 490 3.4E-41 T 29-03-2018 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 4.1E-47 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 4.1E-47 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 4.1E-47 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 4.1E-47 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 4.1E-47 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 4.1E-47 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 4.1E-47 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 4.1E-47 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 4.1E-47 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 SUPERFAMILY SSF82866 289 486 4.45E-40 T 29-03-2018 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 SUPERFAMILY SSF82866 804 1026 1.22E-52 T 29-03-2018 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 Gene3D G3DSA:3.30.2090.10 715 802 9.0E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 Pfam PF00873 AcrB/AcrD/AcrF family 3 1020 9.5E-254 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 SUPERFAMILY SSF82693 41 134 3.4E-24 T 29-03-2018 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 Gene3D G3DSA:3.30.2090.10 179 264 1.6E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 SUPERFAMILY SSF82714 717 799 9.16E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 SUPERFAMILY SSF82714 181 264 9.16E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 SUPERFAMILY SSF82693 137 180 1.92E-20 T 29-03-2018 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 SUPERFAMILY SSF82693 266 322 1.92E-20 T 29-03-2018 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 Gene3D G3DSA:3.30.70.1430 40 141 3.2E-26 T 29-03-2018 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 Gene3D G3DSA:1.20.1640.10 813 1034 1.1E-46 T 29-03-2018 CB4_RS14150 e7fb117947e723543f782e97ff5fcd73 1053 Gene3D G3DSA:3.30.70.1430 565 666 1.5E-21 T 29-03-2018 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 SUPERFAMILY SSF49785 51 181 7.09E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 SUPERFAMILY SSF52172 691 823 1.02E-37 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 SMART SM00388 429 497 7.6E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Pfam PF00512 His Kinase A (phospho-acceptor) domain 430 497 1.4E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 SUPERFAMILY SSF55874 487 654 4.71E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Pfam PF07695 7TM diverse intracellular signalling 209 405 1.6E-17 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Pfam PF06580 Histidine kinase 822 901 1.8E-23 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 SUPERFAMILY SSF47384 420 498 6.47E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 SMART SM00448 691 805 3.1E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 SMART SM00387 543 654 5.4E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 SMART SM00387 915 1016 0.028 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Pfam PF00072 Response regulator receiver domain 693 805 1.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Gene3D G3DSA:2.60.120.260 48 212 2.2E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Gene3D G3DSA:1.10.287.130 419 493 9.1E-16 T 29-03-2018 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Gene3D G3DSA:3.40.50.2300 686 824 4.4E-35 T 29-03-2018 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 607 1.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 579 593 1.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 638 651 1.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 PRINTS PR00344 Bacterial sensor protein C-terminal signature 614 632 1.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Gene3D G3DSA:3.30.565.10 503 663 4.6E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Gene3D G3DSA:3.30.565.10 832 1012 2.8E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 544 652 2.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 920 1014 5.5E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09875 894bc8773e1871f386cc094033fedec2 1017 SUPERFAMILY SSF55874 877 1011 4.19E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09165 0ce9ef5d3b5c922dbbc4859cdab7df80 204 Pfam PF04347 Flagellar biosynthesis protein, FliO 71 159 2.9E-11 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CB4_RS05805 f0749fb4962f3c7f72f2efb7c31eebe4 223 Gene3D G3DSA:3.40.140.10 110 222 1.6E-51 T 29-03-2018 CB4_RS05805 f0749fb4962f3c7f72f2efb7c31eebe4 223 Gene3D G3DSA:1.10.150.20 77 109 0.36 T 29-03-2018 CB4_RS05805 f0749fb4962f3c7f72f2efb7c31eebe4 223 SUPERFAMILY SSF102712 115 190 5.62E-5 T 29-03-2018 CB4_RS05805 f0749fb4962f3c7f72f2efb7c31eebe4 223 Gene3D G3DSA:1.10.150.20 37 76 3.7E-4 T 29-03-2018 CB4_RS05805 f0749fb4962f3c7f72f2efb7c31eebe4 223 TIGRFAM TIGR00608 radc: DNA repair protein RadC 10 221 1.0E-75 T 29-03-2018 IPR001405 RadC protein CB4_RS05805 f0749fb4962f3c7f72f2efb7c31eebe4 223 SUPERFAMILY SSF47781 20 89 5.72E-6 T 29-03-2018 IPR010994 RuvA domain 2-like CB4_RS05805 f0749fb4962f3c7f72f2efb7c31eebe4 223 Pfam PF04002 RadC-like JAB domain 102 220 1.0E-47 T 29-03-2018 IPR025657 RadC-like JAB domain CB4_RS05805 f0749fb4962f3c7f72f2efb7c31eebe4 223 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 171 176 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CB4_RS12555 d656dd01b24ff4d6e0b7a1828f68b0f3 168 SUPERFAMILY SSF52540 4 161 1.92E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12555 d656dd01b24ff4d6e0b7a1828f68b0f3 168 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 6 158 5.9E-42 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CB4_RS12555 d656dd01b24ff4d6e0b7a1828f68b0f3 168 Gene3D G3DSA:3.40.50.300 1 165 4.8E-30 T 29-03-2018 CB4_RS12555 d656dd01b24ff4d6e0b7a1828f68b0f3 168 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 6 132 3.7E-43 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 69 197 1.7E-51 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 206 228 5.3E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 126 140 5.3E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 384 395 5.3E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 248 268 5.3E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 SMART SM00839 217 458 6.5E-98 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 SUPERFAMILY SSF51735 215 459 2.5E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 215 458 4.4E-93 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 PIRSF PIRSF000185 31 460 3.2E-123 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 Gene3D G3DSA:3.40.50.10860 77 202 5.9E-56 T 29-03-2018 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 Gene3D G3DSA:1.10.285.10 386 460 2.0E-30 T 29-03-2018 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 Gene3D G3DSA:1.10.285.10 18 76 3.0E-10 T 29-03-2018 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 Gene3D G3DSA:3.40.50.720 222 385 8.9E-47 T 29-03-2018 CB4_RS02250 3ef1e1ff6e1d1cea3561476db209745f 460 SUPERFAMILY SSF53223 18 209 2.27E-76 T 29-03-2018 CB4_RS00965 c3e59be276a5a0fab7cfc51244cf47d3 456 SMART SM00283 209 456 6.6E-32 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS00965 c3e59be276a5a0fab7cfc51244cf47d3 456 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 262 438 1.8E-32 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS00965 c3e59be276a5a0fab7cfc51244cf47d3 456 Gene3D G3DSA:1.10.287.950 406 456 0.008 T 29-03-2018 CB4_RS00965 c3e59be276a5a0fab7cfc51244cf47d3 456 Gene3D G3DSA:1.10.287.950 223 405 2.6E-37 T 29-03-2018 CB4_RS00965 c3e59be276a5a0fab7cfc51244cf47d3 456 Gene3D G3DSA:1.10.490.10 29 198 8.8E-33 T 29-03-2018 CB4_RS00965 c3e59be276a5a0fab7cfc51244cf47d3 456 SUPERFAMILY SSF58104 215 454 1.29E-52 T 29-03-2018 CB4_RS00965 c3e59be276a5a0fab7cfc51244cf47d3 456 Pfam PF11563 Protoglobin 46 196 1.2E-35 T 29-03-2018 CB4_RS00965 c3e59be276a5a0fab7cfc51244cf47d3 456 SUPERFAMILY SSF46458 40 192 1.14E-29 T 29-03-2018 IPR009050 Globin-like CB4_RS13145 13c4c6f9502fc75d691289797551bc5d 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CB4_RS13145 13c4c6f9502fc75d691289797551bc5d 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 5.3E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS13145 13c4c6f9502fc75d691289797551bc5d 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 5.3E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS13145 13c4c6f9502fc75d691289797551bc5d 195 Gene3D G3DSA:1.10.10.60 49 141 1.8E-9 T 29-03-2018 CB4_RS13145 13c4c6f9502fc75d691289797551bc5d 195 SUPERFAMILY SSF46689 7 65 1.75E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS13145 13c4c6f9502fc75d691289797551bc5d 195 Gene3D G3DSA:1.10.10.60 2 48 2.4E-19 T 29-03-2018 CB4_RS13145 13c4c6f9502fc75d691289797551bc5d 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 6.6E-19 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS17780 9648690f70738fc14d7ff7d12331c791 241 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 14 237 36.383 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CB4_RS17780 9648690f70738fc14d7ff7d12331c791 241 Pfam PF04055 Radical SAM superfamily 41 125 4.4E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS17780 9648690f70738fc14d7ff7d12331c791 241 PIRSF PIRSF000370 13 240 1.8E-49 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CB4_RS17780 9648690f70738fc14d7ff7d12331c791 241 Pfam PF13394 4Fe-4S single cluster domain 36 122 6.0E-11 T 29-03-2018 CB4_RS17780 9648690f70738fc14d7ff7d12331c791 241 Gene3D G3DSA:3.20.20.70 39 170 8.9E-18 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS17780 9648690f70738fc14d7ff7d12331c791 241 SUPERFAMILY SSF102114 40 127 7.72E-15 T 29-03-2018 CB4_RS07235 8d9992e315dcda19d612717557d3e967 222 SUPERFAMILY SSF53335 1 219 1.15E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS07235 8d9992e315dcda19d612717557d3e967 222 Gene3D G3DSA:3.40.50.150 1 220 1.3E-34 T 29-03-2018 CB4_RS07235 8d9992e315dcda19d612717557d3e967 222 Pfam PF13649 Methyltransferase domain 42 136 2.6E-19 T 29-03-2018 CB4_RS15810 34e0570231d0cfa8df37287ea4fccc98 105 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 46 93 2.0E-11 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CB4_RS15810 34e0570231d0cfa8df37287ea4fccc98 105 Gene3D G3DSA:1.10.1660.20 61 101 3.1E-4 T 29-03-2018 CB4_RS15810 34e0570231d0cfa8df37287ea4fccc98 105 Gene3D G3DSA:1.10.10.60 32 60 0.0018 T 29-03-2018 CB4_RS15810 34e0570231d0cfa8df37287ea4fccc98 105 Pfam PF12728 Helix-turn-helix domain 45 97 1.9E-12 T 29-03-2018 CB4_RS05130 d6007baf59a1a99c4482180ea11aa531 332 SUPERFAMILY SSF47240 43 280 3.89E-66 T 29-03-2018 IPR009078 Ferritin-like superfamily CB4_RS05130 d6007baf59a1a99c4482180ea11aa531 332 Gene3D G3DSA:1.10.620.20 11 299 4.9E-66 T 29-03-2018 CB4_RS05130 d6007baf59a1a99c4482180ea11aa531 332 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 23 318 6.1E-126 T 29-03-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 CB4_RS05130 d6007baf59a1a99c4482180ea11aa531 332 Pfam PF05138 Phenylacetic acid catabolic protein 33 299 9.2E-82 T 29-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 22 569 2.7E-222 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 TIGRFAM TIGR00422 valS: valine--tRNA ligase 10 866 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 819 883 1.7E-24 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 SUPERFAMILY SSF50677 199 349 3.79E-64 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 Pfam PF08264 Anticodon-binding domain of tRNA 613 759 7.9E-44 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 Hamap MF_02004 Valine--tRNA ligase [valS]. 10 884 16.206 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 Gene3D G3DSA:1.10.730.10 571 751 8.3E-61 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 Gene3D G3DSA:3.40.50.620 11 569 3.7E-146 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 Gene3D G3DSA:1.10.287.380 812 882 8.6E-26 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 PRINTS PR00986 Valyl-tRNA synthetase signature 482 500 4.4E-39 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 PRINTS PR00986 Valyl-tRNA synthetase signature 44 55 4.4E-39 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 PRINTS PR00986 Valyl-tRNA synthetase signature 353 366 4.4E-39 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 PRINTS PR00986 Valyl-tRNA synthetase signature 451 472 4.4E-39 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 PRINTS PR00986 Valyl-tRNA synthetase signature 238 255 4.4E-39 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 51 62 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 SUPERFAMILY SSF47323 582 833 4.67E-78 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 SUPERFAMILY SSF52374 10 198 6.5E-152 T 29-03-2018 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 SUPERFAMILY SSF52374 348 580 6.5E-152 T 29-03-2018 CB4_RS05710 5ddf19413960638d374dfa3eafaec7d3 885 SUPERFAMILY SSF46589 819 883 2.2E-16 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CB4_RS07060 3c7f7e8c9b8f16d47722cda4a2d173d5 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 20.794 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS07060 3c7f7e8c9b8f16d47722cda4a2d173d5 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 29-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS07060 3c7f7e8c9b8f16d47722cda4a2d173d5 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 2.0E-6 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS07060 3c7f7e8c9b8f16d47722cda4a2d173d5 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.5E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS07060 3c7f7e8c9b8f16d47722cda4a2d173d5 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.5E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS07060 3c7f7e8c9b8f16d47722cda4a2d173d5 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.5E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS07060 3c7f7e8c9b8f16d47722cda4a2d173d5 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.5E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS07060 3c7f7e8c9b8f16d47722cda4a2d173d5 57 Gene3D G3DSA:1.20.5.1150 16 52 1.1E-18 T 29-03-2018 CB4_RS07060 3c7f7e8c9b8f16d47722cda4a2d173d5 57 Pfam PF01165 Ribosomal protein S21 3 57 5.9E-22 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS07060 3c7f7e8c9b8f16d47722cda4a2d173d5 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 1.9E-22 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS16680 3ce414eee5b499fcfdbc40a19a2dcc10 483 Gene3D G3DSA:3.50.50.60 1 474 7.5E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16680 3ce414eee5b499fcfdbc40a19a2dcc10 483 PIRSF PIRSF038984 1 101 4.5E-8 T 29-03-2018 IPR028348 FAD dependent protein CB4_RS16680 3ce414eee5b499fcfdbc40a19a2dcc10 483 PIRSF PIRSF038984 131 479 2.7E-20 T 29-03-2018 IPR028348 FAD dependent protein CB4_RS16680 3ce414eee5b499fcfdbc40a19a2dcc10 483 SUPERFAMILY SSF51905 432 477 8.99E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16680 3ce414eee5b499fcfdbc40a19a2dcc10 483 SUPERFAMILY SSF51905 110 242 8.99E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16680 3ce414eee5b499fcfdbc40a19a2dcc10 483 SUPERFAMILY SSF51905 74 82 8.99E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS16680 3ce414eee5b499fcfdbc40a19a2dcc10 483 SUPERFAMILY SSF51905 1 36 8.99E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS07420 fce699d3c154b0d50aedfcefe237db49 1260 SUPERFAMILY SSF52540 44 264 1.75E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07420 fce699d3c154b0d50aedfcefe237db49 1260 Gene3D G3DSA:3.40.50.300 629 1238 6.0E-39 T 29-03-2018 CB4_RS07420 fce699d3c154b0d50aedfcefe237db49 1260 Gene3D G3DSA:3.40.50.300 22 500 2.3E-36 T 29-03-2018 CB4_RS07420 fce699d3c154b0d50aedfcefe237db49 1260 Pfam PF00350 Dynamin family 646 871 1.4E-38 T 29-03-2018 IPR022812 Dynamin superfamily CB4_RS07420 fce699d3c154b0d50aedfcefe237db49 1260 Pfam PF00350 Dynamin family 59 213 1.0E-27 T 29-03-2018 IPR022812 Dynamin superfamily CB4_RS07420 fce699d3c154b0d50aedfcefe237db49 1260 SUPERFAMILY SSF52540 784 910 3.75E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07420 fce699d3c154b0d50aedfcefe237db49 1260 SUPERFAMILY SSF52540 628 696 3.75E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS20140 33e583ab5d76a6d2a0a5b7ec15ab04eb 864 SUPERFAMILY SSF48452 549 773 8.59E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS20140 33e583ab5d76a6d2a0a5b7ec15ab04eb 864 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 818 834 1.1E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS20140 33e583ab5d76a6d2a0a5b7ec15ab04eb 864 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 804 818 1.1E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS20140 33e583ab5d76a6d2a0a5b7ec15ab04eb 864 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 834 846 1.1E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS20140 33e583ab5d76a6d2a0a5b7ec15ab04eb 864 Gene3D G3DSA:1.10.10.10 799 864 2.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS20140 33e583ab5d76a6d2a0a5b7ec15ab04eb 864 ProSitePatterns PS00622 LuxR-type HTH domain signature. 818 845 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS20140 33e583ab5d76a6d2a0a5b7ec15ab04eb 864 Pfam PF00196 Bacterial regulatory proteins, luxR family 804 854 5.3E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS20140 33e583ab5d76a6d2a0a5b7ec15ab04eb 864 SUPERFAMILY SSF46894 790 863 5.1E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS20140 33e583ab5d76a6d2a0a5b7ec15ab04eb 864 Gene3D G3DSA:1.25.40.10 206 793 2.0E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS20140 33e583ab5d76a6d2a0a5b7ec15ab04eb 864 SMART SM00421 801 858 4.8E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS06370 7c965febf93a05ede0227a0a4a148199 535 SUPERFAMILY SSF89372 44 268 2.35E-12 T 29-03-2018 CB4_RS06370 7c965febf93a05ede0227a0a4a148199 535 TIGRFAM TIGR02543 List_Bact_rpt: repeat, TIGR02543 family 435 473 6.3E-5 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS06370 7c965febf93a05ede0227a0a4a148199 535 Gene3D G3DSA:1.10.1330.10 478 531 3.2E-6 T 29-03-2018 CB4_RS06370 7c965febf93a05ede0227a0a4a148199 535 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 399 468 2.0E-6 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CB4_RS06370 7c965febf93a05ede0227a0a4a148199 535 Gene3D G3DSA:2.120.10.10 244 477 0.0058 T 29-03-2018 CB4_RS06370 7c965febf93a05ede0227a0a4a148199 535 SUPERFAMILY SSF89372 203 432 1.44E-8 T 29-03-2018 CB4_RS06370 7c965febf93a05ede0227a0a4a148199 535 Gene3D G3DSA:2.120.10.10 41 243 3.4E-11 T 29-03-2018 CB4_RS06370 7c965febf93a05ede0227a0a4a148199 535 SUPERFAMILY SSF63446 474 529 3.92E-11 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 366 1.3E-147 T 29-03-2018 IPR010162 Peptidase M20B, peptidase T-like CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 SUPERFAMILY SSF53187 5 177 7.07E-61 T 29-03-2018 CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 SUPERFAMILY SSF53187 287 368 7.07E-61 T 29-03-2018 CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 Gene3D G3DSA:3.40.630.10 2 372 1.5E-61 T 29-03-2018 CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 Pfam PF01546 Peptidase family M20/M25/M40 73 367 1.1E-21 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 104 142 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 Pfam PF07687 Peptidase dimerisation domain 179 273 9.3E-14 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 SUPERFAMILY SSF55031 177 284 5.1E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 PIRSF PIRSF001123 299 372 0.0018 T 29-03-2018 IPR008007 Peptidase M42 CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 PIRSF PIRSF001123 4 83 0.021 T 29-03-2018 IPR008007 Peptidase M42 CB4_RS16345 f820dbcaa55c60e652e198ad03cc012e 372 PIRSF PIRSF001123 91 187 1.4E-4 T 29-03-2018 IPR008007 Peptidase M42 CB4_RS16075 e756b45ff93d5be1944ccb08e648e47b 609 Pfam PF05154 TM2 domain 3 51 2.4E-12 T 29-03-2018 IPR007829 TM2 domain CB4_RS16075 e756b45ff93d5be1944ccb08e648e47b 609 Pfam PF15615 TerB-C domain 452 598 2.0E-18 T 29-03-2018 IPR028932 TerB-C domain CB4_RS16075 e756b45ff93d5be1944ccb08e648e47b 609 Pfam PF13208 TerB N-terminal domain 134 290 4.1E-26 T 29-03-2018 IPR025266 TerB, N-terminal CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 PIRSF PIRSF016578 2 377 3.3E-24 T 29-03-2018 CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 4.1E-52 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 Gene3D G3DSA:2.40.110.10 121 217 1.4E-41 T 29-03-2018 CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 SUPERFAMILY SSF56645 2 240 2.23E-93 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 5.2E-29 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 9.1E-40 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 Gene3D G3DSA:1.20.140.10 218 380 2.0E-65 T 29-03-2018 CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 Gene3D G3DSA:1.10.540.10 1 120 1.1E-38 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CB4_RS02765 38fc88d84bfce8fc2584ae97b9ab423b 380 SUPERFAMILY SSF47203 227 379 9.02E-62 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CB4_RS06155 4618222be171892e81de4fa9ec33e036 401 PIRSF PIRSF016719 1 401 3.3E-113 T 29-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CB4_RS06155 4618222be171892e81de4fa9ec33e036 401 Pfam PF07075 Protein of unknown function (DUF1343) 56 400 5.1E-109 T 29-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CB4_RS12275 ed3f1b55a3bccc13810e0c32f50c164e 233 Gene3D G3DSA:1.20.144.10 20 233 2.5E-29 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS12275 ed3f1b55a3bccc13810e0c32f50c164e 233 SUPERFAMILY SSF48317 27 226 1.96E-40 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS12275 ed3f1b55a3bccc13810e0c32f50c164e 233 SMART SM00014 103 217 4.9E-31 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS12275 ed3f1b55a3bccc13810e0c32f50c164e 233 Pfam PF01569 PAP2 superfamily 106 222 3.2E-21 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS06695 e95f935bac8f241f544af6aadbe64ede 344 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 342 36.35 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CB4_RS06695 e95f935bac8f241f544af6aadbe64ede 344 Gene3D G3DSA:3.40.50.150 116 308 2.0E-47 T 29-03-2018 CB4_RS06695 e95f935bac8f241f544af6aadbe64ede 344 SUPERFAMILY SSF53335 98 302 2.69E-49 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS06695 e95f935bac8f241f544af6aadbe64ede 344 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 301 1.7E-101 T 29-03-2018 CB4_RS06695 e95f935bac8f241f544af6aadbe64ede 344 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 301 5.5E-92 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CB4_RS06695 e95f935bac8f241f544af6aadbe64ede 344 PIRSF PIRSF000401 1 304 1.4E-104 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CB4_RS06695 e95f935bac8f241f544af6aadbe64ede 344 PIRSF PIRSF000401 326 343 670.0 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CB4_RS08485 fb84e0101ee7716f73fd6144ce28218e 152 PRINTS PR01576 Peptide deformylase signature 86 97 1.1E-34 T 29-03-2018 IPR023635 Peptide deformylase CB4_RS08485 fb84e0101ee7716f73fd6144ce28218e 152 PRINTS PR01576 Peptide deformylase signature 117 146 1.1E-34 T 29-03-2018 IPR023635 Peptide deformylase CB4_RS08485 fb84e0101ee7716f73fd6144ce28218e 152 PRINTS PR01576 Peptide deformylase signature 98 116 1.1E-34 T 29-03-2018 IPR023635 Peptide deformylase CB4_RS08485 fb84e0101ee7716f73fd6144ce28218e 152 PRINTS PR01576 Peptide deformylase signature 33 62 1.1E-34 T 29-03-2018 IPR023635 Peptide deformylase CB4_RS08485 fb84e0101ee7716f73fd6144ce28218e 152 PIRSF PIRSF004749 1 149 4.8E-50 T 29-03-2018 IPR023635 Peptide deformylase CB4_RS08485 fb84e0101ee7716f73fd6144ce28218e 152 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 148 2.8E-51 T 29-03-2018 IPR023635 Peptide deformylase CB4_RS08485 fb84e0101ee7716f73fd6144ce28218e 152 SUPERFAMILY SSF56420 3 147 4.84E-56 T 29-03-2018 IPR023635 Peptide deformylase CB4_RS08485 fb84e0101ee7716f73fd6144ce28218e 152 Gene3D G3DSA:3.90.45.10 1 151 3.2E-56 T 29-03-2018 IPR023635 Peptide deformylase CB4_RS08485 fb84e0101ee7716f73fd6144ce28218e 152 Hamap MF_00163 Peptide deformylase [def]. 2 152 29.046 T 29-03-2018 IPR023635 Peptide deformylase CB4_RS08485 fb84e0101ee7716f73fd6144ce28218e 152 Pfam PF01327 Polypeptide deformylase 4 146 5.9E-49 T 29-03-2018 IPR023635 Peptide deformylase CB4_RS00225 7813646664b95167d884852f8bccc9bb 491 Pfam PF00171 Aldehyde dehydrogenase family 14 477 6.9E-184 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS00225 7813646664b95167d884852f8bccc9bb 491 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CB4_RS00225 7813646664b95167d884852f8bccc9bb 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CB4_RS00225 7813646664b95167d884852f8bccc9bb 491 Gene3D G3DSA:3.40.309.10 266 463 6.6E-80 T 29-03-2018 CB4_RS00225 7813646664b95167d884852f8bccc9bb 491 SUPERFAMILY SSF53720 4 480 1.1E-177 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS00225 7813646664b95167d884852f8bccc9bb 491 Gene3D G3DSA:3.40.605.10 2 265 4.5E-104 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS19120 bcd817adb38d41d5a1dd6ed5e6925cb8 261 Pfam PF06182 ABC-2 family transporter protein 33 260 1.3E-47 T 29-03-2018 IPR010390 Protein of unknown function DUF990 CB4_RS05760 ed970f45370a9180ae89098750a41bc8 347 Gene3D G3DSA:3.30.450.90 4 103 1.4E-25 T 29-03-2018 CB4_RS05760 ed970f45370a9180ae89098750a41bc8 347 Pfam PF00437 Type II/IV secretion system protein 15 271 8.6E-42 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CB4_RS05760 ed970f45370a9180ae89098750a41bc8 347 SUPERFAMILY SSF52540 7 331 1.6E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05760 ed970f45370a9180ae89098750a41bc8 347 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 6 336 4.4E-145 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 CB4_RS05760 ed970f45370a9180ae89098750a41bc8 347 Gene3D G3DSA:3.40.50.300 118 275 4.5E-30 T 29-03-2018 CB4_RS05760 ed970f45370a9180ae89098750a41bc8 347 Gene3D G3DSA:3.40.50.300 276 346 2.5E-9 T 29-03-2018 CB4_RS05760 ed970f45370a9180ae89098750a41bc8 347 SMART SM00382 125 250 4.3E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS05760 ed970f45370a9180ae89098750a41bc8 347 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 196 210 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CB4_RS00175 d958f8c7d31ae1c6e5b4903953c129e6 255 SMART SM00382 30 225 1.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS00175 d958f8c7d31ae1c6e5b4903953c129e6 255 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS00175 d958f8c7d31ae1c6e5b4903953c129e6 255 SUPERFAMILY SSF52540 3 231 1.54E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00175 d958f8c7d31ae1c6e5b4903953c129e6 255 Pfam PF00005 ABC transporter 21 169 8.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS00175 d958f8c7d31ae1c6e5b4903953c129e6 255 Gene3D G3DSA:3.40.50.300 2 251 1.2E-58 T 29-03-2018 CB4_RS09370 27d53fb646735a6d9169304bd3276b93 415 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CB4_RS09370 27d53fb646735a6d9169304bd3276b93 415 Pfam PF05193 Peptidase M16 inactive domain 165 339 8.7E-39 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CB4_RS09370 27d53fb646735a6d9169304bd3276b93 415 SUPERFAMILY SSF63411 3 204 1.91E-59 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CB4_RS09370 27d53fb646735a6d9169304bd3276b93 415 Gene3D G3DSA:3.30.830.10 238 413 1.4E-45 T 29-03-2018 CB4_RS09370 27d53fb646735a6d9169304bd3276b93 415 SUPERFAMILY SSF63411 222 402 3.03E-49 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CB4_RS09370 27d53fb646735a6d9169304bd3276b93 415 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 8.5E-44 T 29-03-2018 IPR011765 Peptidase M16, N-terminal CB4_RS09370 27d53fb646735a6d9169304bd3276b93 415 Gene3D G3DSA:3.30.830.10 1 215 7.4E-59 T 29-03-2018 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 Gene3D G3DSA:2.40.50.250 484 574 2.3E-36 T 29-03-2018 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 600 4.3E-289 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 Gene3D G3DSA:3.40.50.300 1 69 3.8E-8 T 29-03-2018 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 Gene3D G3DSA:2.40.30.10 193 304 1.3E-21 T 29-03-2018 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 SUPERFAMILY SSF54980 304 388 3.96E-14 T 29-03-2018 IPR035647 EF-G domain III/V-like CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 PRINTS PR00315 GTP-binding elongation factor signature 73 83 7.5E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 PRINTS PR00315 GTP-binding elongation factor signature 125 134 7.5E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 PRINTS PR00315 GTP-binding elongation factor signature 53 61 7.5E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 PRINTS PR00315 GTP-binding elongation factor signature 89 100 7.5E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 PRINTS PR00315 GTP-binding elongation factor signature 9 22 7.5E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 Gene3D G3DSA:3.30.70.240 402 481 7.3E-17 T 29-03-2018 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 Pfam PF00009 Elongation factor Tu GTP binding domain 6 197 3.4E-56 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 Pfam PF00679 Elongation factor G C-terminus 398 476 2.5E-22 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 SUPERFAMILY SSF52540 3 208 9.14E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 141 1.2E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 Gene3D G3DSA:3.40.50.300 70 192 2.8E-29 T 29-03-2018 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 SUPERFAMILY SSF54980 399 514 5.76E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 Pfam PF03144 Elongation factor Tu domain 2 221 290 2.1E-11 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 SMART SM00838 399 481 0.0064 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 Gene3D G3DSA:3.30.70.870 305 401 3.1E-32 T 29-03-2018 CB4_RS17895 db792257363b76bcaabbfb92e4c38f0e 608 SUPERFAMILY SSF50447 153 301 2.95E-32 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CB4_RS10505 8e2d78b35ab2eac915f8b8c9840446aa 155 SUPERFAMILY SSF109854 5 152 7.33E-24 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CB4_RS10505 8e2d78b35ab2eac915f8b8c9840446aa 155 Gene3D G3DSA:1.20.120.450 3 151 3.7E-19 T 29-03-2018 CB4_RS10505 8e2d78b35ab2eac915f8b8c9840446aa 155 Pfam PF12867 DinB superfamily 9 146 9.4E-16 T 29-03-2018 IPR024775 DinB-like domain CB4_RS05785 21547af69cb6937325bd8f07eef878e1 203 Pfam PF05137 Fimbrial assembly protein (PilN) 96 158 5.3E-9 T 29-03-2018 IPR007813 Fimbrial assembly PilN CB4_RS17910 c2bd186804d139b3a2c1a1840b96e4ea 262 SUPERFAMILY SSF53474 14 258 1.16E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS17910 c2bd186804d139b3a2c1a1840b96e4ea 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 1.6E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS17910 c2bd186804d139b3a2c1a1840b96e4ea 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 41 56 1.6E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS17910 c2bd186804d139b3a2c1a1840b96e4ea 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 1.6E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS17910 c2bd186804d139b3a2c1a1840b96e4ea 262 Pfam PF12146 Serine aminopeptidase, S33 12 246 5.8E-61 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CB4_RS17910 c2bd186804d139b3a2c1a1840b96e4ea 262 Gene3D G3DSA:3.40.50.1820 2 262 1.7E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS05025 1dadc29cb0e4ace670f49dfcdf595b55 493 SUPERFAMILY SSF52540 2 219 1.41E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05025 1dadc29cb0e4ace670f49dfcdf595b55 493 SMART SM00382 23 223 1.6E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS05025 1dadc29cb0e4ace670f49dfcdf595b55 493 SMART SM00382 275 469 1.0E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS05025 1dadc29cb0e4ace670f49dfcdf595b55 493 Gene3D G3DSA:3.40.50.300 252 485 5.8E-35 T 29-03-2018 CB4_RS05025 1dadc29cb0e4ace670f49dfcdf595b55 493 ProSitePatterns PS00211 ABC transporters family signature. 393 407 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS05025 1dadc29cb0e4ace670f49dfcdf595b55 493 Gene3D G3DSA:3.40.50.300 1 225 6.9E-47 T 29-03-2018 CB4_RS05025 1dadc29cb0e4ace670f49dfcdf595b55 493 Pfam PF00005 ABC transporter 267 420 6.8E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS05025 1dadc29cb0e4ace670f49dfcdf595b55 493 Pfam PF00005 ABC transporter 14 167 6.8E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS05025 1dadc29cb0e4ace670f49dfcdf595b55 493 SUPERFAMILY SSF52540 245 473 1.07E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09075 b03043b0ce7474fb60988b862dbf5d71 135 PIRSF PIRSF002889 2 135 8.5E-32 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CB4_RS09075 b03043b0ce7474fb60988b862dbf5d71 135 Pfam PF00460 Flagella basal body rod protein 10 37 4.2E-6 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CB4_RS09075 b03043b0ce7474fb60988b862dbf5d71 135 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 132 1.7E-32 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CB4_RS02725 66ae63797193dd48e72b4b1bf7ecfebc 276 Gene3D G3DSA:2.30.140.10 5 52 8.7E-21 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CB4_RS02725 66ae63797193dd48e72b4b1bf7ecfebc 276 Pfam PF01564 Spermine/spermidine synthase domain 59 237 8.6E-66 T 29-03-2018 CB4_RS02725 66ae63797193dd48e72b4b1bf7ecfebc 276 Gene3D G3DSA:3.40.50.150 57 276 1.4E-42 T 29-03-2018 CB4_RS02725 66ae63797193dd48e72b4b1bf7ecfebc 276 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 80 93 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CB4_RS02725 66ae63797193dd48e72b4b1bf7ecfebc 276 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 4 276 40.025 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CB4_RS02725 66ae63797193dd48e72b4b1bf7ecfebc 276 Pfam PF17284 Spermidine synthase tetramerisation domain 5 55 1.2E-20 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CB4_RS02725 66ae63797193dd48e72b4b1bf7ecfebc 276 SUPERFAMILY SSF53335 2 275 2.86E-87 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS02725 66ae63797193dd48e72b4b1bf7ecfebc 276 TIGRFAM TIGR00417 speE: spermidine synthase 5 270 3.8E-114 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CB4_RS18535 23f08a5d24427b937766027f7943ac93 365 Gene3D G3DSA:3.30.1490.20 139 204 1.2E-6 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS18535 23f08a5d24427b937766027f7943ac93 365 Gene3D G3DSA:3.30.470.20 205 339 1.7E-11 T 29-03-2018 CB4_RS18535 23f08a5d24427b937766027f7943ac93 365 Pfam PF14398 YheC/D like ATP-grasp 102 356 1.9E-69 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CB4_RS18535 23f08a5d24427b937766027f7943ac93 365 SUPERFAMILY SSF56059 151 349 6.28E-10 T 29-03-2018 CB4_RS06595 464c187b84f7c12135ee942f5467ac78 167 Gene3D G3DSA:3.40.140.10 1 159 1.1E-35 T 29-03-2018 CB4_RS06595 464c187b84f7c12135ee942f5467ac78 167 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 128 1.6E-23 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CB4_RS06595 464c187b84f7c12135ee942f5467ac78 167 PIRSF PIRSF006019 1 162 8.3E-43 T 29-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CB4_RS06595 464c187b84f7c12135ee942f5467ac78 167 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 84 117 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CB4_RS06595 464c187b84f7c12135ee942f5467ac78 167 SUPERFAMILY SSF53927 8 153 1.39E-32 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CB4_RS16775 b8ab9ccc3af7980f756a46a7015c40b8 464 Gene3D G3DSA:1.10.490.10 46 210 6.3E-35 T 29-03-2018 CB4_RS16775 b8ab9ccc3af7980f756a46a7015c40b8 464 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 292 450 7.4E-30 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS16775 b8ab9ccc3af7980f756a46a7015c40b8 464 SUPERFAMILY SSF58104 223 457 1.7E-47 T 29-03-2018 CB4_RS16775 b8ab9ccc3af7980f756a46a7015c40b8 464 Pfam PF11563 Protoglobin 64 208 5.5E-35 T 29-03-2018 CB4_RS16775 b8ab9ccc3af7980f756a46a7015c40b8 464 SMART SM00283 217 457 9.8E-22 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS16775 b8ab9ccc3af7980f756a46a7015c40b8 464 SUPERFAMILY SSF46458 54 201 3.6E-31 T 29-03-2018 IPR009050 Globin-like CB4_RS16775 b8ab9ccc3af7980f756a46a7015c40b8 464 Gene3D G3DSA:1.10.287.950 243 464 2.2E-41 T 29-03-2018 CB4_RS17190 3c98e47c059aa859f3ebe45de0632b47 437 Gene3D G3DSA:3.50.50.60 2 423 5.0E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17190 3c98e47c059aa859f3ebe45de0632b47 437 SUPERFAMILY SSF160996 194 362 5.75E-43 T 29-03-2018 CB4_RS17190 3c98e47c059aa859f3ebe45de0632b47 437 Pfam PF03486 HI0933-like protein 5 413 1.7E-141 T 29-03-2018 CB4_RS17190 3c98e47c059aa859f3ebe45de0632b47 437 SUPERFAMILY SSF51905 359 418 1.37E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17190 3c98e47c059aa859f3ebe45de0632b47 437 SUPERFAMILY SSF51905 3 195 1.37E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17190 3c98e47c059aa859f3ebe45de0632b47 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.3E-7 T 29-03-2018 CB4_RS17190 3c98e47c059aa859f3ebe45de0632b47 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 169 3.3E-7 T 29-03-2018 CB4_RS17190 3c98e47c059aa859f3ebe45de0632b47 437 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 413 2.0E-133 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CB4_RS17190 3c98e47c059aa859f3ebe45de0632b47 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.4E-6 T 29-03-2018 CB4_RS17190 3c98e47c059aa859f3ebe45de0632b47 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 6.4E-6 T 29-03-2018 CB4_RS13435 a8dff0a3b53344cb6e6a0c4667e388e8 86 ProDom PD058323 YUZF BH2251 14 75 3.0E-11 T 29-03-2018 IPR020139 Protein of unknown function DUF2642 CB4_RS13435 a8dff0a3b53344cb6e6a0c4667e388e8 86 Pfam PF10842 Protein of unknown function (DUF2642) 14 75 3.6E-24 T 29-03-2018 IPR020139 Protein of unknown function DUF2642 CB4_RS04405 bb983e730078f19466349de041b3a874 545 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 59 521 2.8E-174 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS04405 bb983e730078f19466349de041b3a874 545 PIRSF PIRSF005690 44 536 3.3E-165 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 Gene3D G3DSA:3.40.1190.10 96 320 7.3E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 29 459 1.9E-123 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 SUPERFAMILY SSF53244 326 459 1.16E-31 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 326 407 1.9E-13 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 Pfam PF08245 Mur ligase middle domain 112 301 7.0E-44 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 Gene3D G3DSA:3.90.190.20 323 460 2.2E-38 T 29-03-2018 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 Pfam PF01225 Mur ligase family, catalytic domain 24 99 1.1E-5 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 Gene3D G3DSA:3.40.1390.10 2 95 4.5E-23 T 29-03-2018 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 2 460 31.456 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 SUPERFAMILY SSF53623 107 321 6.15E-51 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS07055 f36f2ec291475b2e0a1b0b718664f6d1 460 SUPERFAMILY SSF63418 2 104 6.67E-20 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CB4_RS07680 4e03c9002d8d96eee8261d2bf787e151 124 Pfam PF07885 Ion channel 33 104 2.1E-11 T 29-03-2018 IPR013099 Potassium channel domain CB4_RS07680 4e03c9002d8d96eee8261d2bf787e151 124 Gene3D G3DSA:1.10.287.70 1 108 1.2E-16 T 29-03-2018 CB4_RS07680 4e03c9002d8d96eee8261d2bf787e151 124 SUPERFAMILY SSF81324 7 103 3.53E-15 T 29-03-2018 CB4_RS19960 7570bc9569fd566224096e0fa6bc77d1 213 Gene3D G3DSA:1.10.10.10 16 87 2.8E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19960 7570bc9569fd566224096e0fa6bc77d1 213 Pfam PF13276 HTH-like domain 27 83 6.4E-17 T 29-03-2018 IPR025948 HTH-like domain CB4_RS19960 7570bc9569fd566224096e0fa6bc77d1 213 SUPERFAMILY SSF53098 102 190 3.03E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS19960 7570bc9569fd566224096e0fa6bc77d1 213 Pfam PF00665 Integrase core domain 107 188 2.2E-20 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CB4_RS19960 7570bc9569fd566224096e0fa6bc77d1 213 Gene3D G3DSA:3.30.420.10 95 195 4.0E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS03690 73f4e3078b8cce5052be81fe29e32721 244 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 5 236 1.5E-82 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CB4_RS03690 73f4e3078b8cce5052be81fe29e32721 244 Gene3D G3DSA:3.20.20.70 4 243 4.4E-50 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS03690 73f4e3078b8cce5052be81fe29e32721 244 SUPERFAMILY SSF51366 4 239 4.16E-69 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CB4_RS03690 73f4e3078b8cce5052be81fe29e32721 244 Pfam PF00977 Histidine biosynthesis protein 5 232 6.4E-75 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CB4_RS03690 73f4e3078b8cce5052be81fe29e32721 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 240 36.55 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CB4_RS01420 803593c670e4563ef1785ebcc3b75e9f 393 SUPERFAMILY SSF52540 2 132 6.32E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01420 803593c670e4563ef1785ebcc3b75e9f 393 SUPERFAMILY SSF52540 215 359 6.32E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01420 803593c670e4563ef1785ebcc3b75e9f 393 PIRSF PIRSF029347 1 367 8.4E-36 T 29-03-2018 IPR014555 RecF-like CB4_RS01420 803593c670e4563ef1785ebcc3b75e9f 393 Gene3D G3DSA:3.40.50.300 1 364 2.1E-25 T 29-03-2018 CB4_RS01420 803593c670e4563ef1785ebcc3b75e9f 393 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 26 340 2.4E-30 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS01960 da7a5dfd3346a7eb0cb931ffc714ccce 285 SMART SM00470 25 114 1.2E-33 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CB4_RS01960 da7a5dfd3346a7eb0cb931ffc714ccce 285 Gene3D G3DSA:1.10.10.730 115 162 3.0E-19 T 29-03-2018 CB4_RS01960 da7a5dfd3346a7eb0cb931ffc714ccce 285 SUPERFAMILY SSF110849 26 170 2.67E-35 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CB4_RS01960 da7a5dfd3346a7eb0cb931ffc714ccce 285 Pfam PF02195 ParB-like nuclease domain 28 113 1.3E-26 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CB4_RS01960 da7a5dfd3346a7eb0cb931ffc714ccce 285 Gene3D G3DSA:3.90.1530.10 14 114 1.5E-35 T 29-03-2018 CB4_RS01960 da7a5dfd3346a7eb0cb931ffc714ccce 285 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 26 197 5.2E-62 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CB4_RS05650 e723d7c7a600875ccd771cd5ec0779e4 511 Gene3D G3DSA:3.30.420.40 2 120 2.0E-36 T 29-03-2018 CB4_RS05650 e723d7c7a600875ccd771cd5ec0779e4 511 SUPERFAMILY SSF109604 315 507 1.29E-29 T 29-03-2018 CB4_RS05650 e723d7c7a600875ccd771cd5ec0779e4 511 SUPERFAMILY SSF53067 7 129 1.86E-31 T 29-03-2018 CB4_RS05650 e723d7c7a600875ccd771cd5ec0779e4 511 Pfam PF02541 Ppx/GppA phosphatase family 24 305 8.6E-58 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CB4_RS05650 e723d7c7a600875ccd771cd5ec0779e4 511 Gene3D G3DSA:3.30.420.150 121 301 1.1E-38 T 29-03-2018 CB4_RS05650 e723d7c7a600875ccd771cd5ec0779e4 511 SUPERFAMILY SSF53067 131 304 4.32E-39 T 29-03-2018 CB4_RS05650 e723d7c7a600875ccd771cd5ec0779e4 511 PIRSF PIRSF001267 1 501 1.1E-85 T 29-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 CB4_RS05650 e723d7c7a600875ccd771cd5ec0779e4 511 Gene3D G3DSA:1.10.3210.10 302 499 0.0015 T 29-03-2018 CB4_RS03505 e8b9a413ad78d269c5e994b9ff70d26c 186 Gene3D G3DSA:3.30.160.100 1 98 1.2E-33 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CB4_RS03505 e8b9a413ad78d269c5e994b9ff70d26c 186 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 126 180 5.6E-30 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CB4_RS03505 e8b9a413ad78d269c5e994b9ff70d26c 186 SUPERFAMILY SSF69754 1 101 1.31E-34 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CB4_RS03505 e8b9a413ad78d269c5e994b9ff70d26c 186 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 100 7.8E-34 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CB4_RS03505 e8b9a413ad78d269c5e994b9ff70d26c 186 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 94 4.6E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CB4_RS03505 e8b9a413ad78d269c5e994b9ff70d26c 186 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 184 25.912 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CB4_RS11750 a283ce0fa770162a54cb0c51081600bf 147 Gene3D G3DSA:1.10.10.10 9 140 4.6E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS11750 a283ce0fa770162a54cb0c51081600bf 147 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 5 141 3.8E-26 T 29-03-2018 IPR006524 Transcription activator, ArpU family CB4_RS11750 a283ce0fa770162a54cb0c51081600bf 147 SUPERFAMILY SSF88659 68 136 9.91E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS14055 8081cdd1341bfc7714078b23639dcce5 476 SUPERFAMILY SSF53383 121 474 8.58E-78 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS14055 8081cdd1341bfc7714078b23639dcce5 476 SUPERFAMILY SSF46785 5 84 1.16E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14055 8081cdd1341bfc7714078b23639dcce5 476 SMART SM00345 16 75 0.0015 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS14055 8081cdd1341bfc7714078b23639dcce5 476 Pfam PF00155 Aminotransferase class I and II 156 445 5.6E-15 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS14055 8081cdd1341bfc7714078b23639dcce5 476 Gene3D G3DSA:3.40.640.10 164 364 2.6E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS14055 8081cdd1341bfc7714078b23639dcce5 476 Gene3D G3DSA:3.90.1150.10 365 475 3.3E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS14055 8081cdd1341bfc7714078b23639dcce5 476 Gene3D G3DSA:1.10.10.10 1 89 3.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14055 8081cdd1341bfc7714078b23639dcce5 476 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 75 3.3E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS17955 480c153c36c8e292c27e73d9647a5dc5 58 Gene3D G3DSA:3.40.630.30 1 58 1.5E-4 T 29-03-2018 CB4_RS17955 480c153c36c8e292c27e73d9647a5dc5 58 Pfam PF13673 Acetyltransferase (GNAT) domain 5 53 2.4E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS17955 480c153c36c8e292c27e73d9647a5dc5 58 SUPERFAMILY SSF55729 2 57 1.64E-7 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS03195 35e5d62ab884791a35d7411b3ea5b960 214 SUPERFAMILY SSF51161 41 212 1.1E-33 T 29-03-2018 IPR011004 Trimeric LpxA-like CB4_RS03195 35e5d62ab884791a35d7411b3ea5b960 214 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 4 208 1.8E-50 T 29-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like CB4_RS03195 35e5d62ab884791a35d7411b3ea5b960 214 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 124 157 8.8E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS03195 35e5d62ab884791a35d7411b3ea5b960 214 Gene3D G3DSA:3.40.50.720 2 96 3.8E-13 T 29-03-2018 CB4_RS03195 35e5d62ab884791a35d7411b3ea5b960 214 Gene3D G3DSA:2.160.10.10 97 214 5.8E-29 T 29-03-2018 CB4_RS07635 94c85a6611d721ea206df164e55d6679 120 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS07635 94c85a6611d721ea206df164e55d6679 120 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 34 7.9E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS07635 94c85a6611d721ea206df164e55d6679 120 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 34 3.7E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS07635 94c85a6611d721ea206df164e55d6679 120 PRINTS PR00813 Bacterial general secretion pathway protein G signature 13 38 1.0E-7 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CB4_RS07635 94c85a6611d721ea206df164e55d6679 120 PRINTS PR00813 Bacterial general secretion pathway protein G signature 49 67 1.0E-7 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CB4_RS07635 94c85a6611d721ea206df164e55d6679 120 SUPERFAMILY SSF54523 14 112 3.61E-17 T 29-03-2018 CB4_RS07635 94c85a6611d721ea206df164e55d6679 120 Gene3D G3DSA:3.30.700.10 14 119 9.5E-18 T 29-03-2018 CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 207 3.4E-29 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 SUPERFAMILY SSF101386 367 463 7.85E-25 T 29-03-2018 CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 Gene3D G3DSA:1.10.287.1080 233 351 2.0E-38 T 29-03-2018 CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 PIRSF PIRSF002845 1 488 1.0E-204 T 29-03-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 Gene3D G3DSA:3.40.1010.10 2 120 2.1E-20 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 256 329 1.2E-25 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 393 453 7.4E-7 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 TIGRFAM TIGR00444 mazG: MazG family protein 240 484 1.9E-95 T 29-03-2018 IPR011551 NTP pyrophosphohydrolase MazG CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 SUPERFAMILY SSF53790 3 258 1.74E-33 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 Gene3D G3DSA:1.10.287.1080 369 490 6.2E-27 T 29-03-2018 CB4_RS01450 fddcca9b6a31f01a5b89b8200ebe0286 493 SUPERFAMILY SSF101386 235 334 5.4E-22 T 29-03-2018 CB4_RS06130 320843746153caf1d74d1f5c46f33b7a 309 Gene3D G3DSA:3.20.20.70 8 290 1.1E-6 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS06130 320843746153caf1d74d1f5c46f33b7a 309 Pfam PF01136 Peptidase family U32 75 306 1.3E-61 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CB4_RS06410 cac7c4c9fd05150430ae8da0de4427c2 61 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS06410 cac7c4c9fd05150430ae8da0de4427c2 61 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS06410 cac7c4c9fd05150430ae8da0de4427c2 61 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 7.6E-22 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CB4_RS07575 40398637f782d27558671f4e3a4805e0 147 SMART SM00418 67 146 1.3E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS07575 40398637f782d27558671f4e3a4805e0 147 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 102 117 1.3E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS07575 40398637f782d27558671f4e3a4805e0 147 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.3E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS07575 40398637f782d27558671f4e3a4805e0 147 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 117 132 1.3E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS07575 40398637f782d27558671f4e3a4805e0 147 Gene3D G3DSA:1.10.10.10 50 147 6.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07575 40398637f782d27558671f4e3a4805e0 147 SUPERFAMILY SSF46785 55 145 6.83E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07575 40398637f782d27558671f4e3a4805e0 147 Pfam PF12840 Helix-turn-helix domain 68 125 2.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14600 1a2285953a7085a277600c661929cda1 351 Gene3D G3DSA:3.30.1490.100 242 351 1.8E-24 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CB4_RS14600 1a2285953a7085a277600c661929cda1 351 Hamap MF_01113 DNA polymerase IV [dinB]. 1 349 29.908 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CB4_RS14600 1a2285953a7085a277600c661929cda1 351 SUPERFAMILY SSF100879 241 350 6.91E-20 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CB4_RS14600 1a2285953a7085a277600c661929cda1 351 Gene3D G3DSA:3.30.70.270 116 168 1.5E-12 T 29-03-2018 CB4_RS14600 1a2285953a7085a277600c661929cda1 351 Gene3D G3DSA:3.30.70.270 40 115 9.1E-21 T 29-03-2018 CB4_RS14600 1a2285953a7085a277600c661929cda1 351 Gene3D G3DSA:1.10.150.20 169 241 1.7E-19 T 29-03-2018 CB4_RS14600 1a2285953a7085a277600c661929cda1 351 Pfam PF11799 impB/mucB/samB family C-terminal domain 240 340 2.2E-17 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CB4_RS14600 1a2285953a7085a277600c661929cda1 351 Pfam PF00817 impB/mucB/samB family 6 151 4.6E-46 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CB4_RS14600 1a2285953a7085a277600c661929cda1 351 SUPERFAMILY SSF56672 1 232 1.07E-67 T 29-03-2018 CB4_RS06625 4730a98d60733e4e6eb302ebba463349 353 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 346 1.5E-77 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CB4_RS06625 4730a98d60733e4e6eb302ebba463349 353 Pfam PF06144 DNA polymerase III, delta subunit 19 194 3.2E-43 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CB4_RS06625 4730a98d60733e4e6eb302ebba463349 353 Gene3D G3DSA:1.20.272.10 227 348 4.1E-30 T 29-03-2018 CB4_RS06625 4730a98d60733e4e6eb302ebba463349 353 Gene3D G3DSA:3.40.50.300 1 145 9.5E-27 T 29-03-2018 CB4_RS06625 4730a98d60733e4e6eb302ebba463349 353 SUPERFAMILY SSF48019 219 345 1.67E-19 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CB4_RS06625 4730a98d60733e4e6eb302ebba463349 353 Gene3D G3DSA:1.10.8.60 148 226 1.5E-21 T 29-03-2018 CB4_RS06625 4730a98d60733e4e6eb302ebba463349 353 SUPERFAMILY SSF52540 8 211 2.57E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS04800 c4ad5ce9dc288b37097f76dfa23a020a 155 Pfam PF13581 Histidine kinase-like ATPase domain 13 132 4.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS04800 c4ad5ce9dc288b37097f76dfa23a020a 155 Gene3D G3DSA:3.30.565.10 5 128 5.7E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS04800 c4ad5ce9dc288b37097f76dfa23a020a 155 SUPERFAMILY SSF55874 28 122 3.8E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09295 0e462c52979acc7df48c6424d20c7e31 412 Pfam PF02163 Peptidase family M50 7 398 1.9E-73 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CB4_RS09295 0e462c52979acc7df48c6424d20c7e31 412 SMART SM00228 186 255 9.3E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS09295 0e462c52979acc7df48c6424d20c7e31 412 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 411 2.4E-98 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CB4_RS09295 0e462c52979acc7df48c6424d20c7e31 412 Pfam PF13180 PDZ domain 206 257 2.4E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS09295 0e462c52979acc7df48c6424d20c7e31 412 SUPERFAMILY SSF50156 170 264 2.37E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS09295 0e462c52979acc7df48c6424d20c7e31 412 Gene3D G3DSA:2.30.42.10 200 280 1.1E-16 T 29-03-2018 CB4_RS20345 6b001188543793078036400dd1482a03 427 SUPERFAMILY SSF52440 1 101 4.6E-37 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS20345 6b001188543793078036400dd1482a03 427 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 420 44.541 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CB4_RS20345 6b001188543793078036400dd1482a03 427 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CB4_RS20345 6b001188543793078036400dd1482a03 427 Gene3D G3DSA:3.30.1490.20 85 187 1.0E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS20345 6b001188543793078036400dd1482a03 427 Gene3D G3DSA:3.90.600.10 328 420 2.0E-36 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CB4_RS20345 6b001188543793078036400dd1482a03 427 Gene3D G3DSA:3.30.470.20 189 327 6.5E-60 T 29-03-2018 CB4_RS20345 6b001188543793078036400dd1482a03 427 Gene3D G3DSA:3.40.50.20 2 84 3.7E-40 T 29-03-2018 CB4_RS20345 6b001188543793078036400dd1482a03 427 SMART SM01210 328 420 2.6E-53 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CB4_RS20345 6b001188543793078036400dd1482a03 427 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 6.1E-78 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CB4_RS20345 6b001188543793078036400dd1482a03 427 SMART SM01209 101 293 3.5E-130 T 29-03-2018 CB4_RS20345 6b001188543793078036400dd1482a03 427 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 3.3E-37 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CB4_RS20345 6b001188543793078036400dd1482a03 427 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 420 4.3E-172 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CB4_RS20345 6b001188543793078036400dd1482a03 427 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 417 5.4E-31 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CB4_RS20345 6b001188543793078036400dd1482a03 427 SUPERFAMILY SSF51246 326 420 5.76E-31 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CB4_RS20345 6b001188543793078036400dd1482a03 427 SUPERFAMILY SSF56059 102 317 1.34E-62 T 29-03-2018 CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 60 289 1.0E-64 T 29-03-2018 CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 218 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 52 69 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 254 274 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 237 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 138 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 189 2.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 Gene3D G3DSA:3.40.50.720 2 293 3.4E-82 T 29-03-2018 CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 186 214 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 199 218 7.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 179 187 7.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 138 7.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS17565 a243545dcc09aa815ada5106529f4700 294 SUPERFAMILY SSF51735 49 292 1.1E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS00080 73f9e4ea3b0608b26b4d4bfee3ac5a85 229 SUPERFAMILY SSF53187 34 219 1.16E-38 T 29-03-2018 CB4_RS00080 73f9e4ea3b0608b26b4d4bfee3ac5a85 229 Gene3D G3DSA:3.40.630.40 29 222 6.6E-43 T 29-03-2018 CB4_RS00080 73f9e4ea3b0608b26b4d4bfee3ac5a85 229 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 34 216 7.2E-37 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CB4_RS00080 73f9e4ea3b0608b26b4d4bfee3ac5a85 229 SMART SM00646 115 216 1.6E-6 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CB4_RS18180 f2cbee751bd1779002d6bae0b629edb6 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.7E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CB4_RS18180 f2cbee751bd1779002d6bae0b629edb6 328 SMART SM00354 1 71 3.3E-36 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CB4_RS18180 f2cbee751bd1779002d6bae0b629edb6 328 Gene3D G3DSA:3.40.50.2300 164 328 5.0E-48 T 29-03-2018 CB4_RS18180 f2cbee751bd1779002d6bae0b629edb6 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.7E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CB4_RS18180 f2cbee751bd1779002d6bae0b629edb6 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.7E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CB4_RS18180 f2cbee751bd1779002d6bae0b629edb6 328 SUPERFAMILY SSF47413 1 59 6.38E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS18180 f2cbee751bd1779002d6bae0b629edb6 328 SUPERFAMILY SSF53822 61 326 1.22E-82 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS18180 f2cbee751bd1779002d6bae0b629edb6 328 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 305 1.5E-37 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CB4_RS18180 f2cbee751bd1779002d6bae0b629edb6 328 Gene3D G3DSA:3.40.50.2300 58 163 2.3E-31 T 29-03-2018 CB4_RS18180 f2cbee751bd1779002d6bae0b629edb6 328 Gene3D G3DSA:1.10.260.40 2 57 1.1E-21 T 29-03-2018 CB4_RS15725 69195844e2846b0077408f0fda28c905 337 Gene3D G3DSA:3.40.190.10 142 320 8.1E-20 T 29-03-2018 CB4_RS15725 69195844e2846b0077408f0fda28c905 337 SUPERFAMILY SSF53850 72 334 2.08E-27 T 29-03-2018 CB4_RS15725 69195844e2846b0077408f0fda28c905 337 Pfam PF09084 NMT1/THI5 like 84 264 6.4E-5 T 29-03-2018 IPR015168 SsuA/THI5-like CB4_RS15725 69195844e2846b0077408f0fda28c905 337 PIRSF PIRSF027386 11 336 1.1E-67 T 29-03-2018 IPR027024 ABC-type uncharacterised transport system, substrate-binding component, TM0202 type CB4_RS08780 cca8e7fb3d21e860a99e0ecd445decd6 85 Gene3D G3DSA:2.40.128.20 2 85 5.9E-4 T 29-03-2018 IPR012674 Calycin CB4_RS00400 aaf66bb5f0c9feb2b3e7dff9f58b9ca7 142 Pfam PF12802 MarR family 32 83 5.2E-12 T 29-03-2018 CB4_RS00400 aaf66bb5f0c9feb2b3e7dff9f58b9ca7 142 SMART SM00347 27 124 4.2E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00400 aaf66bb5f0c9feb2b3e7dff9f58b9ca7 142 Gene3D G3DSA:1.10.10.10 6 141 7.8E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00400 aaf66bb5f0c9feb2b3e7dff9f58b9ca7 142 SUPERFAMILY SSF46785 7 127 2.32E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS10490 7355269950ed302e6d536c1f69a9c98c 66 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS10490 7355269950ed302e6d536c1f69a9c98c 66 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS10490 7355269950ed302e6d536c1f69a9c98c 66 PRINTS PR00050 Cold shock protein signature 39 57 1.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS10490 7355269950ed302e6d536c1f69a9c98c 66 SUPERFAMILY SSF50249 1 65 4.68E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS10490 7355269950ed302e6d536c1f69a9c98c 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CB4_RS10490 7355269950ed302e6d536c1f69a9c98c 66 SMART SM00357 3 66 1.6E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CB4_RS10490 7355269950ed302e6d536c1f69a9c98c 66 PIRSF PIRSF002599 1 66 4.7E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CB4_RS10490 7355269950ed302e6d536c1f69a9c98c 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.0E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS10490 7355269950ed302e6d536c1f69a9c98c 66 Gene3D G3DSA:2.40.50.140 1 66 2.7E-29 T 29-03-2018 CB4_RS08025 21f6d801621b6749182ff854688141d9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 6.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08025 21f6d801621b6749182ff854688141d9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 6.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08025 21f6d801621b6749182ff854688141d9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 6.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08025 21f6d801621b6749182ff854688141d9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 6.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS08025 21f6d801621b6749182ff854688141d9 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 3.6E-86 T 29-03-2018 CB4_RS08025 21f6d801621b6749182ff854688141d9 256 Gene3D G3DSA:3.40.50.720 2 256 1.3E-47 T 29-03-2018 CB4_RS08025 21f6d801621b6749182ff854688141d9 256 PIRSF PIRSF000094 1 256 2.1E-105 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CB4_RS08025 21f6d801621b6749182ff854688141d9 256 SUPERFAMILY SSF51735 5 255 3.39E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS12900 b45df6b8e7cfb0d9e52d09670e87047a 142 SMART SM00347 26 126 2.4E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS12900 b45df6b8e7cfb0d9e52d09670e87047a 142 Pfam PF01047 MarR family 33 90 2.5E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS12900 b45df6b8e7cfb0d9e52d09670e87047a 142 Gene3D G3DSA:1.10.10.10 3 140 5.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12900 b45df6b8e7cfb0d9e52d09670e87047a 142 SUPERFAMILY SSF46785 10 138 2.66E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09025 bb25d4f4f3edcf4dee6c22a5dca159a0 42 SUPERFAMILY SSF100985 1 40 4.58E-13 T 29-03-2018 IPR015064 Sporulation inhibitor A CB4_RS09025 bb25d4f4f3edcf4dee6c22a5dca159a0 42 Gene3D G3DSA:1.10.287.1100 4 36 3.1E-14 T 29-03-2018 IPR015064 Sporulation inhibitor A CB4_RS09025 bb25d4f4f3edcf4dee6c22a5dca159a0 42 Pfam PF08970 Sporulation inhibitor A 1 40 2.7E-16 T 29-03-2018 IPR015064 Sporulation inhibitor A CB4_RS17705 09488ca86e2bf94ef5ec95f408f92e49 65 Pfam PF12669 Virus attachment protein p12 family 3 44 4.3E-9 T 29-03-2018 CB4_RS19715 c9529a0b61899792942bd186719ddc67 265 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 256 6.4E-86 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CB4_RS19715 c9529a0b61899792942bd186719ddc67 265 Pfam PF02673 Bacitracin resistance protein BacA 7 258 2.1E-82 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CB4_RS19715 c9529a0b61899792942bd186719ddc67 265 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 263 17.929 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CB4_RS15925 05e82290e0bf8981168c4ed4c08ed2c9 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 228 3.9E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS15925 05e82290e0bf8981168c4ed4c08ed2c9 235 Gene3D G3DSA:1.10.10.10 127 235 3.2E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15925 05e82290e0bf8981168c4ed4c08ed2c9 235 Pfam PF00072 Response regulator receiver domain 6 115 3.8E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS15925 05e82290e0bf8981168c4ed4c08ed2c9 235 SUPERFAMILY SSF46894 135 230 1.42E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS15925 05e82290e0bf8981168c4ed4c08ed2c9 235 Gene3D G3DSA:3.40.50.2300 1 126 7.1E-40 T 29-03-2018 CB4_RS15925 05e82290e0bf8981168c4ed4c08ed2c9 235 SMART SM00862 154 228 1.6E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS15925 05e82290e0bf8981168c4ed4c08ed2c9 235 SMART SM00448 4 114 1.3E-47 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS15925 05e82290e0bf8981168c4ed4c08ed2c9 235 SUPERFAMILY SSF52172 2 127 7.4E-44 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS19575 f39650d925548a580a5ae3a584ded5fa 707 Gene3D G3DSA:3.30.420.10 277 513 2.8E-24 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS19575 f39650d925548a580a5ae3a584ded5fa 707 Pfam PF00665 Integrase core domain 281 419 9.9E-14 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CB4_RS19575 f39650d925548a580a5ae3a584ded5fa 707 SUPERFAMILY SSF53098 283 475 1.26E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS08460 d51453b5b4d9b07daf1cd7f912a5a8f8 86 Pfam PF04025 Domain of unknown function (DUF370) 5 77 3.4E-37 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CB4_RS08460 d51453b5b4d9b07daf1cd7f912a5a8f8 86 Hamap MF_01503 UPF0296 protein . 3 86 29.56 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CB4_RS08460 d51453b5b4d9b07daf1cd7f912a5a8f8 86 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 78 6.0E-34 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CB4_RS14060 d56fbbc71803bb7ae5621178e4bec89d 396 PIRSF PIRSF000521 161 391 3.9E-38 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS14060 d56fbbc71803bb7ae5621178e4bec89d 396 PIRSF PIRSF000521 11 158 4.0E-7 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS14060 d56fbbc71803bb7ae5621178e4bec89d 396 Pfam PF00202 Aminotransferase class-III 14 388 5.9E-114 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS14060 d56fbbc71803bb7ae5621178e4bec89d 396 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 8 388 1.1E-145 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CB4_RS14060 d56fbbc71803bb7ae5621178e4bec89d 396 SUPERFAMILY SSF53383 7 391 2.39E-122 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS14060 d56fbbc71803bb7ae5621178e4bec89d 396 Gene3D G3DSA:3.90.1150.10 285 391 3.4E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS14060 d56fbbc71803bb7ae5621178e4bec89d 396 Gene3D G3DSA:3.40.640.10 171 284 1.8E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS14060 d56fbbc71803bb7ae5621178e4bec89d 396 Gene3D G3DSA:3.90.1150.10 1 170 3.5E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS14060 d56fbbc71803bb7ae5621178e4bec89d 396 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 6 389 44.235 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CB4_RS14060 d56fbbc71803bb7ae5621178e4bec89d 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 215 252 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS01485 8dec800414c1ca24834024e365542530 316 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 9 316 50.983 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CB4_RS01485 8dec800414c1ca24834024e365542530 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 315 2.1E-27 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CB4_RS01485 8dec800414c1ca24834024e365542530 316 SMART SM01400 9 125 1.2E-80 T 29-03-2018 CB4_RS01485 8dec800414c1ca24834024e365542530 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 10 316 3.0E-128 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CB4_RS01485 8dec800414c1ca24834024e365542530 316 SUPERFAMILY SSF53271 74 307 4.3E-68 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CB4_RS01485 8dec800414c1ca24834024e365542530 316 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 133 148 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CB4_RS01485 8dec800414c1ca24834024e365542530 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 9 125 3.1E-50 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CB4_RS01485 8dec800414c1ca24834024e365542530 316 Gene3D G3DSA:3.40.50.2020 152 316 1.4E-48 T 29-03-2018 CB4_RS01485 8dec800414c1ca24834024e365542530 316 Gene3D G3DSA:3.40.50.2020 9 151 5.3E-64 T 29-03-2018 CB4_RS16220 41cb39485a884329004c21b9c0ed3a84 467 PIRSF PIRSF016636 1 467 2.0E-141 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CB4_RS16220 41cb39485a884329004c21b9c0ed3a84 467 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 50 341 2.1E-24 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CB4_RS16220 41cb39485a884329004c21b9c0ed3a84 467 PIRSF PIRSF500217 1 467 3.3E-147 T 29-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CB4_RS20735 e51bbc0753e4c6e992afbf0318744134 155 Pfam PF01584 CheW-like domain 9 142 1.2E-31 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS20735 e51bbc0753e4c6e992afbf0318744134 155 SMART SM00260 5 142 6.8E-27 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS20735 e51bbc0753e4c6e992afbf0318744134 155 Gene3D G3DSA:2.30.30.40 90 136 1.2E-13 T 29-03-2018 CB4_RS20735 e51bbc0753e4c6e992afbf0318744134 155 SUPERFAMILY SSF50341 6 142 1.1E-32 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS20735 e51bbc0753e4c6e992afbf0318744134 155 Gene3D G3DSA:2.40.50.180 1 30 0.021 T 29-03-2018 CB4_RS20735 e51bbc0753e4c6e992afbf0318744134 155 Gene3D G3DSA:2.40.50.180 31 89 3.0E-21 T 29-03-2018 CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 PRINTS PR00958 Homoserine kinase signature 113 128 4.0E-5 T 29-03-2018 CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 PRINTS PR00958 Homoserine kinase signature 178 195 4.0E-5 T 29-03-2018 CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 PRINTS PR00958 Homoserine kinase signature 251 266 4.0E-5 T 29-03-2018 CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 13 290 36.027 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 PIRSF PIRSF010376 11 297 1.4E-96 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 Gene3D G3DSA:3.30.70.890 171 296 2.0E-29 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 12 296 6.9E-102 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 Pfam PF08544 GHMP kinases C terminal 208 281 2.0E-10 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 SUPERFAMILY SSF54211 13 166 5.31E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 Pfam PF00288 GHMP kinases N terminal domain 96 154 2.2E-14 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 Gene3D G3DSA:3.30.230.10 13 169 3.2E-51 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS01510 ad48e96050bf2354b2a4106631261f49 298 SUPERFAMILY SSF55060 171 292 2.65E-32 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CB4_RS10655 d82e7091e4bed449377465f868e5b9ff 134 Pfam PF00575 S1 RNA binding domain 5 75 3.3E-19 T 29-03-2018 IPR003029 S1 domain GO:0003676 CB4_RS10655 d82e7091e4bed449377465f868e5b9ff 134 Gene3D G3DSA:2.40.50.140 7 123 4.2E-26 T 29-03-2018 CB4_RS10655 d82e7091e4bed449377465f868e5b9ff 134 SUPERFAMILY SSF50249 3 77 2.06E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS10655 d82e7091e4bed449377465f868e5b9ff 134 SMART SM00316 5 75 2.5E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS07800 fa7954fc2ca3bb4fe2c0545d41e9e5b7 266 Gene3D G3DSA:1.20.1290.10 21 150 1.3E-28 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CB4_RS07800 fa7954fc2ca3bb4fe2c0545d41e9e5b7 266 Gene3D G3DSA:1.20.1290.10 151 266 2.5E-34 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CB4_RS07800 fa7954fc2ca3bb4fe2c0545d41e9e5b7 266 SUPERFAMILY SSF69118 11 264 5.45E-67 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CB4_RS07800 fa7954fc2ca3bb4fe2c0545d41e9e5b7 266 Pfam PF02627 Carboxymuconolactone decarboxylase family 44 127 1.6E-14 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CB4_RS07800 fa7954fc2ca3bb4fe2c0545d41e9e5b7 266 Pfam PF02627 Carboxymuconolactone decarboxylase family 177 261 4.1E-19 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CB4_RS02355 ed7c89ec4a237acbfd3e52bb730860e1 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.1E-19 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS02355 ed7c89ec4a237acbfd3e52bb730860e1 191 SUPERFAMILY SSF46689 5 78 1.75E-21 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS02355 ed7c89ec4a237acbfd3e52bb730860e1 191 Pfam PF13305 WHG domain 90 162 1.0E-6 T 29-03-2018 IPR025996 WHG domain CB4_RS02355 ed7c89ec4a237acbfd3e52bb730860e1 191 SUPERFAMILY SSF48498 84 190 2.11E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS02355 ed7c89ec4a237acbfd3e52bb730860e1 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS02355 ed7c89ec4a237acbfd3e52bb730860e1 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS02355 ed7c89ec4a237acbfd3e52bb730860e1 191 Gene3D G3DSA:1.10.357.10 69 191 1.1E-10 T 29-03-2018 CB4_RS02355 ed7c89ec4a237acbfd3e52bb730860e1 191 Gene3D G3DSA:1.10.10.60 7 68 6.0E-22 T 29-03-2018 CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 SUPERFAMILY SSF55785 33 145 1.65E-25 T 29-03-2018 IPR000014 PAS domain CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 Gene3D G3DSA:1.10.287.130 152 216 4.1E-14 T 29-03-2018 CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 SMART SM00387 262 369 3.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 Pfam PF00512 His Kinase A (phospho-acceptor) domain 158 218 1.8E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 SMART SM00091 27 93 7.2E-10 T 29-03-2018 IPR000014 PAS domain CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 SUPERFAMILY SSF55874 213 367 9.3E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 SMART SM00086 100 142 3.2E-9 T 29-03-2018 IPR001610 PAC motif CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 Gene3D G3DSA:3.30.565.10 220 375 1.2E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 263 368 3.0E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 Gene3D G3DSA:3.30.450.20 3 151 3.5E-32 T 29-03-2018 CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 SMART SM00388 157 220 6.6E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 Pfam PF08447 PAS fold 50 133 1.2E-11 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 328 4.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 300 314 4.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 4.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 347 4.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 149 4.0E-32 T 29-03-2018 IPR000014 PAS domain CB4_RS11045 fd49b51498a51843852e784eb61b2b1f 376 SUPERFAMILY SSF47384 150 218 1.8E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS07385 fe7196b60b51913d106aa2ea5f171aed 244 Gene3D G3DSA:3.40.50.150 3 241 1.5E-33 T 29-03-2018 CB4_RS07385 fe7196b60b51913d106aa2ea5f171aed 244 Pfam PF13649 Methyltransferase domain 45 138 1.5E-18 T 29-03-2018 CB4_RS07385 fe7196b60b51913d106aa2ea5f171aed 244 SUPERFAMILY SSF53335 11 242 2.39E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS08955 de8133d55d38871137b440f7f8c9a8b1 472 Gene3D G3DSA:2.30.300.10 328 394 0.0026 T 29-03-2018 CB4_RS09850 c1a4ae3700c66690c765f8633489f34e 393 Pfam PF02803 Thiolase, C-terminal domain 269 390 3.7E-42 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CB4_RS09850 c1a4ae3700c66690c765f8633489f34e 393 Pfam PF00108 Thiolase, N-terminal domain 4 261 1.8E-93 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CB4_RS09850 c1a4ae3700c66690c765f8633489f34e 393 SUPERFAMILY SSF53901 270 390 3.29E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09850 c1a4ae3700c66690c765f8633489f34e 393 Gene3D G3DSA:3.40.47.10 186 264 5.1E-25 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09850 c1a4ae3700c66690c765f8633489f34e 393 Gene3D G3DSA:3.40.47.10 1 185 2.7E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09850 c1a4ae3700c66690c765f8633489f34e 393 SUPERFAMILY SSF53901 3 269 2.76E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS09850 c1a4ae3700c66690c765f8633489f34e 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 1.2E-137 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS09850 c1a4ae3700c66690c765f8633489f34e 393 PIRSF PIRSF000429 1 393 7.5E-124 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CB4_RS09850 c1a4ae3700c66690c765f8633489f34e 393 Gene3D G3DSA:3.40.47.10 265 389 3.1E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS13035 4b45d5c5025d0c6f1c557d8fe0d6b844 109 Gene3D G3DSA:1.10.150.130 1 106 7.7E-18 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CB4_RS13035 4b45d5c5025d0c6f1c557d8fe0d6b844 109 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 3 82 5.9E-11 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CB4_RS13035 4b45d5c5025d0c6f1c557d8fe0d6b844 109 SUPERFAMILY SSF47823 4 87 2.16E-11 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CB4_RS18510 956204b6c7e7d27643c91d36586a11d0 229 Pfam PF13483 Beta-lactamase superfamily domain 2 193 1.1E-23 T 29-03-2018 CB4_RS18510 956204b6c7e7d27643c91d36586a11d0 229 Gene3D G3DSA:3.60.15.10 1 229 3.2E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS18510 956204b6c7e7d27643c91d36586a11d0 229 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 229 36.525 T 29-03-2018 IPR022877 Protein of unknown funcion UPF0173 CB4_RS18510 956204b6c7e7d27643c91d36586a11d0 229 SUPERFAMILY SSF56281 1 217 2.75E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS18510 956204b6c7e7d27643c91d36586a11d0 229 SMART SM00849 7 193 2.4E-7 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 SUPERFAMILY SSF46609 2 91 8.77E-38 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 Gene3D G3DSA:1.10.287.990 21 90 1.5E-31 T 29-03-2018 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 4.4E-44 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 8.3E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 8.3E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 8.3E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 8.3E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 8.3E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 SUPERFAMILY SSF54719 92 201 1.83E-49 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 PIRSF PIRSF000349 1 202 7.7E-88 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS19280 c0248cb14a6bda10194c6877568280b7 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 90 4.3E-33 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CB4_RS18880 5e3cde17a7b889b902e4b433006b6353 519 Pfam PF00239 Resolvase, N terminal domain 10 166 1.0E-19 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18880 5e3cde17a7b889b902e4b433006b6353 519 Pfam PF07508 Recombinase 188 293 3.3E-26 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CB4_RS18880 5e3cde17a7b889b902e4b433006b6353 519 Gene3D G3DSA:1.20.5.340 373 486 0.0059 T 29-03-2018 CB4_RS18880 5e3cde17a7b889b902e4b433006b6353 519 SMART SM00857 9 167 3.6E-23 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18880 5e3cde17a7b889b902e4b433006b6353 519 SUPERFAMILY SSF53041 9 166 1.7E-20 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18880 5e3cde17a7b889b902e4b433006b6353 519 Gene3D G3DSA:3.40.50.1390 4 177 4.2E-31 T 29-03-2018 CB4_RS00245 e10a110570dece74ece64de3ebc6d9bb 193 Pfam PF12007 Protein of unknown function (DUF3501) 3 192 1.5E-55 T 29-03-2018 IPR021890 Protein of unknown function DUF3501 CB4_RS06770 2e762505883bcaec97a95c17ba64dadc 175 SUPERFAMILY SSF49879 57 166 1.91E-13 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CB4_RS06770 2e762505883bcaec97a95c17ba64dadc 175 Gene3D G3DSA:2.60.200.20 29 161 1.4E-14 T 29-03-2018 CB4_RS06770 2e762505883bcaec97a95c17ba64dadc 175 Pfam PF00498 FHA domain 86 152 1.9E-6 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 Gene3D G3DSA:4.10.320.10 130 175 1.5E-21 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 Gene3D G3DSA:3.90.1170.30 2 45 7.5E-14 T 29-03-2018 CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 Gene3D G3DSA:3.90.1170.30 46 129 1.9E-5 T 29-03-2018 CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 Pfam PF02817 e3 binding domain 128 163 5.0E-17 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 Gene3D G3DSA:3.30.559.10 193 440 4.2E-86 T 29-03-2018 CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 SUPERFAMILY SSF47005 121 167 3.01E-14 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 211 439 2.7E-86 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 Pfam PF00364 Biotin-requiring enzyme 4 75 1.3E-22 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 SUPERFAMILY SSF51230 1 95 2.36E-27 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS06500 7564af26c9a5ca276ae459be8072ee58 442 SUPERFAMILY SSF52777 201 439 3.34E-85 T 29-03-2018 CB4_RS01900 ccb883e76304d648a989ae2c4ba9b488 76 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 6 63 7.2E-27 T 29-03-2018 IPR014330 RNA-binding S4-related,YaaA CB4_RS01900 ccb883e76304d648a989ae2c4ba9b488 76 Gene3D G3DSA:3.10.290.10 1 71 5.4E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS01900 ccb883e76304d648a989ae2c4ba9b488 76 Pfam PF13275 S4 domain 6 64 5.6E-27 T 29-03-2018 CB4_RS01900 ccb883e76304d648a989ae2c4ba9b488 76 SUPERFAMILY SSF55174 3 68 8.37E-19 T 29-03-2018 CB4_RS04595 84ba1a06b68dce8e32260992f6a2360f 195 Gene3D G3DSA:4.10.1070.10 54 178 5.7E-9 T 29-03-2018 CB4_RS04595 84ba1a06b68dce8e32260992f6a2360f 195 Gene3D G3DSA:3.90.1340.10 1 53 3.8E-23 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS04595 84ba1a06b68dce8e32260992f6a2360f 195 Pfam PF07484 Phage Tail Collar Domain 6 62 4.6E-26 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS04595 84ba1a06b68dce8e32260992f6a2360f 195 SUPERFAMILY SSF88874 2 189 6.15E-43 T 29-03-2018 CB4_RS07750 ef45c7ec7bdaad4d0604fd985a9bf535 324 SUPERFAMILY SSF55874 183 318 5.5E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS07750 ef45c7ec7bdaad4d0604fd985a9bf535 324 Pfam PF06580 Histidine kinase 128 207 1.8E-22 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CB4_RS07750 ef45c7ec7bdaad4d0604fd985a9bf535 324 Pfam PF00072 Response regulator receiver domain 8 111 7.1E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS07750 ef45c7ec7bdaad4d0604fd985a9bf535 324 Gene3D G3DSA:3.30.565.10 137 318 5.2E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS07750 ef45c7ec7bdaad4d0604fd985a9bf535 324 SUPERFAMILY SSF52172 6 144 2.99E-34 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS07750 ef45c7ec7bdaad4d0604fd985a9bf535 324 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 226 321 2.9E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS07750 ef45c7ec7bdaad4d0604fd985a9bf535 324 Gene3D G3DSA:3.40.50.2300 5 136 1.6E-32 T 29-03-2018 CB4_RS07750 ef45c7ec7bdaad4d0604fd985a9bf535 324 SMART SM00448 1 111 2.9E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13075 c74c8ce1ce278e11d25f408b560c8f50 120 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 3 113 9.8E-33 T 29-03-2018 IPR018745 Domain of unknown function DUF2294 CB4_RS12155 9252fcd135102942eaf8b1fa24cae944 263 SUPERFAMILY SSF56529 46 257 3.27E-55 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS12155 9252fcd135102942eaf8b1fa24cae944 263 TIGRFAM TIGR02305 HpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit 46 251 4.1E-82 T 29-03-2018 IPR012686 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit GO:0008704|GO:0018800 KEGG: 00350+5.3.3.10+4.1.1.68 CB4_RS12155 9252fcd135102942eaf8b1fa24cae944 263 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 48 252 1.0E-46 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS12155 9252fcd135102942eaf8b1fa24cae944 263 Gene3D G3DSA:3.90.850.10 11 260 4.4E-53 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS08935 c840c17a4a97efc4ec443180b8b67d8f 122 Pfam PF11367 Protein of unknown function (DUF3168) 8 110 2.5E-11 T 29-03-2018 IPR021508 Tail completion protein CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 Gene3D G3DSA:1.10.287.950 318 412 1.2E-7 T 29-03-2018 CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 Gene3D G3DSA:1.10.287.950 584 664 7.7E-5 T 29-03-2018 CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 Gene3D G3DSA:1.10.287.950 413 583 1.9E-44 T 29-03-2018 CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 SMART SM00283 390 665 4.7E-73 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 Pfam PF00672 HAMP domain 308 358 1.1E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 SUPERFAMILY SSF58104 396 664 9.68E-66 T 29-03-2018 CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 SUPERFAMILY SSF58104 329 363 9.68E-66 T 29-03-2018 CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 Gene3D G3DSA:3.30.450.20 178 281 7.5E-4 T 29-03-2018 CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 Gene3D G3DSA:3.30.450.20 23 177 0.01 T 29-03-2018 CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 SMART SM00304 307 361 2.7E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS06020 7c5b5f4dabec6ee8017cb82d2b009a7b 666 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 441 597 2.0E-40 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS00935 37b368df75df147b525406a1d9e77ad2 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.461 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00935 37b368df75df147b525406a1d9e77ad2 92 SUPERFAMILY SSF54570 3 83 2.88E-36 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00935 37b368df75df147b525406a1d9e77ad2 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00935 37b368df75df147b525406a1d9e77ad2 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 2.6E-48 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CB4_RS00935 37b368df75df147b525406a1d9e77ad2 92 Gene3D G3DSA:3.30.860.10 1 92 5.7E-41 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00935 37b368df75df147b525406a1d9e77ad2 92 PIRSF PIRSF002144 1 92 7.3E-33 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00935 37b368df75df147b525406a1d9e77ad2 92 Pfam PF00203 Ribosomal protein S19 3 83 8.4E-38 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00935 37b368df75df147b525406a1d9e77ad2 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.5E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00935 37b368df75df147b525406a1d9e77ad2 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.5E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00935 37b368df75df147b525406a1d9e77ad2 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.5E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS20320 f50abccf5120e0b87c898d52e7433e9d 259 Gene3D G3DSA:3.40.50.300 1 259 9.4E-60 T 29-03-2018 CB4_RS20320 f50abccf5120e0b87c898d52e7433e9d 259 SMART SM00382 32 232 3.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS20320 f50abccf5120e0b87c898d52e7433e9d 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 255 2.7E-13 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CB4_RS20320 f50abccf5120e0b87c898d52e7433e9d 259 Pfam PF00005 ABC transporter 25 183 3.8E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS20320 f50abccf5120e0b87c898d52e7433e9d 259 SUPERFAMILY SSF52540 6 256 1.91E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 SUPERFAMILY SSF53223 9 191 2.94E-64 T 29-03-2018 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 43 170 1.1E-53 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 189 420 1.9E-75 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 348 359 4.7E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 222 242 4.7E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 180 202 4.7E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 100 114 4.7E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 SMART SM00839 191 420 3.8E-99 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 108 121 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 PIRSF PIRSF000185 6 423 1.0E-166 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 SUPERFAMILY SSF51735 189 421 2.63E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 Gene3D G3DSA:3.40.50.10860 41 175 1.8E-50 T 29-03-2018 CB4_RS00230 e95909aff99bd626da993dc9cf2dddc1 423 Gene3D G3DSA:3.40.50.720 189 423 8.5E-76 T 29-03-2018 CB4_RS18805 55350aff7e5639545f5fe4a8bae2332a 487 ProSitePatterns PS00397 Site-specific recombinases active site. 16 24 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CB4_RS18805 55350aff7e5639545f5fe4a8bae2332a 487 SUPERFAMILY SSF53041 13 162 8.5E-41 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18805 55350aff7e5639545f5fe4a8bae2332a 487 Gene3D G3DSA:1.20.5.40 133 160 3.5E-13 T 29-03-2018 CB4_RS18805 55350aff7e5639545f5fe4a8bae2332a 487 Pfam PF13408 Recombinase zinc beta ribbon domain 297 355 1.3E-14 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain CB4_RS18805 55350aff7e5639545f5fe4a8bae2332a 487 SMART SM00857 13 162 3.0E-63 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18805 55350aff7e5639545f5fe4a8bae2332a 487 Pfam PF07508 Recombinase 183 284 2.5E-27 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CB4_RS18805 55350aff7e5639545f5fe4a8bae2332a 487 Pfam PF00239 Resolvase, N terminal domain 14 162 8.3E-43 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS18805 55350aff7e5639545f5fe4a8bae2332a 487 Gene3D G3DSA:3.40.50.1390 9 132 2.4E-41 T 29-03-2018 CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 SMART SM00387 283 391 3.1E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 SUPERFAMILY SSF47384 164 236 2.75E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 389 3.5E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 Pfam PF00512 His Kinase A (phospho-acceptor) domain 169 236 7.6E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 Gene3D G3DSA:1.10.287.130 159 234 3.2E-11 T 29-03-2018 CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 Gene3D G3DSA:3.30.565.10 241 394 1.6E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 SMART SM00388 168 238 4.9E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 SUPERFAMILY SSF55874 230 389 1.57E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 336 8.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 369 8.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 388 8.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS09645 cabe21555da6f34fa8e2b94d9dbb173f 395 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 350 8.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13290 7109f7965458ee6916ea37c5105d340b 231 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 105 177 1.3E-13 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CB4_RS13290 7109f7965458ee6916ea37c5105d340b 231 Gene3D G3DSA:3.90.470.20 2 113 2.2E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS13290 7109f7965458ee6916ea37c5105d340b 231 Gene3D G3DSA:3.90.470.20 114 209 5.3E-16 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS13290 7109f7965458ee6916ea37c5105d340b 231 SUPERFAMILY SSF56214 106 227 1.57E-28 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS13290 7109f7965458ee6916ea37c5105d340b 231 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 106 208 5.8E-15 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS13290 7109f7965458ee6916ea37c5105d340b 231 SUPERFAMILY SSF56214 6 99 1.12E-19 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS20510 5344d2a658f4932ef4308a412538911b 157 Pfam PF10263 SprT-like family 7 98 7.5E-12 T 29-03-2018 IPR006640 SprT-like CB4_RS20510 5344d2a658f4932ef4308a412538911b 157 SMART SM00731 4 150 1.6E-49 T 29-03-2018 IPR006640 SprT-like CB4_RS20510 5344d2a658f4932ef4308a412538911b 157 Hamap MF_00745 Protein SprT-like. 4 150 39.32 T 29-03-2018 IPR023524 Uncharacterised protein family SprT-like CB4_RS14800 1394a4fabea619c59a2f168018756953 459 Gene3D G3DSA:3.40.640.10 193 333 4.4E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS14800 1394a4fabea619c59a2f168018756953 459 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS14800 1394a4fabea619c59a2f168018756953 459 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 16 448 1.8E-165 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CB4_RS14800 1394a4fabea619c59a2f168018756953 459 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 4 451 52.736 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CB4_RS14800 1394a4fabea619c59a2f168018756953 459 Gene3D G3DSA:3.90.1150.10 334 456 1.1E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS14800 1394a4fabea619c59a2f168018756953 459 Gene3D G3DSA:3.90.1150.10 2 188 1.6E-51 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS14800 1394a4fabea619c59a2f168018756953 459 Pfam PF00202 Aminotransferase class-III 29 448 2.2E-121 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS14800 1394a4fabea619c59a2f168018756953 459 SUPERFAMILY SSF53383 11 449 1.5E-133 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS14800 1394a4fabea619c59a2f168018756953 459 PIRSF PIRSF000521 22 450 5.1E-40 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS10680 4da5485429d33cbfb46207575494188d 295 SUPERFAMILY SSF51679 1 292 2.94E-72 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CB4_RS10680 4da5485429d33cbfb46207575494188d 295 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 241 6.2E-90 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CB4_RS10680 4da5485429d33cbfb46207575494188d 295 Gene3D G3DSA:3.20.20.30 1 295 1.3E-69 T 29-03-2018 CB4_RS10680 4da5485429d33cbfb46207575494188d 295 Pfam PF00296 Luciferase-like monooxygenase 13 242 1.6E-36 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 SMART SM00382 28 238 2.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 SMART SM00382 350 515 1.5E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 SUPERFAMILY SSF52540 311 510 6.1E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 Gene3D G3DSA:3.40.50.300 292 515 1.9E-37 T 29-03-2018 CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 Pfam PF00005 ABC transporter 343 469 6.6E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 Pfam PF00005 ABC transporter 20 191 2.0E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 SUPERFAMILY SSF52540 4 233 2.39E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 Pfam PF12848 ABC transporter 230 315 6.5E-21 T 29-03-2018 IPR032781 ABC-transporter extension domain CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 Gene3D G3DSA:3.40.50.300 1 291 2.4E-51 T 29-03-2018 CB4_RS11255 4d7cae7230f801fa4c673f3b5ccf1b4b 517 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS01985 076a753cca08e466cada94bb872e0ded 308 SUPERFAMILY SSF50182 123 185 1.34E-15 T 29-03-2018 IPR010920 LSM domain CB4_RS01985 076a753cca08e466cada94bb872e0ded 308 Gene3D G3DSA:3.30.70.100 188 282 2.0E-16 T 29-03-2018 CB4_RS01985 076a753cca08e466cada94bb872e0ded 308 Gene3D G3DSA:2.30.30.60 138 187 8.6E-14 T 29-03-2018 CB4_RS01985 076a753cca08e466cada94bb872e0ded 308 SUPERFAMILY SSF82689 189 284 4.58E-19 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CB4_RS01985 076a753cca08e466cada94bb872e0ded 308 SUPERFAMILY SSF82861 30 121 3.92E-15 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CB4_RS01985 076a753cca08e466cada94bb872e0ded 308 Pfam PF00924 Mechanosensitive ion channel 79 277 1.9E-45 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 Gene3D G3DSA:2.10.109.10 90 206 2.4E-26 T 29-03-2018 CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 SUPERFAMILY SSF51306 84 205 2.27E-36 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 Gene3D G3DSA:1.10.10.10 1 70 2.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 TIGRFAM TIGR00498 lexA: repressor LexA 1 207 3.5E-79 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 SUPERFAMILY SSF46785 3 70 2.7E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 121 131 1.1E-10 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 132 143 1.1E-10 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 161 173 1.1E-10 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 Hamap MF_00015 LexA repressor [lexA]. 3 206 34.779 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 Pfam PF00717 Peptidase S24-like 124 191 6.2E-18 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CB4_RS14015 e009c10015574cdc6a5ce56aa10d6939 207 Pfam PF01726 LexA DNA binding domain 1 65 1.2E-28 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CB4_RS00470 440d895a0cb46cd23445893f4cc1e74f 192 SUPERFAMILY SSF140478 30 178 8.89E-54 T 29-03-2018 IPR023353 LemA-like domain CB4_RS00470 440d895a0cb46cd23445893f4cc1e74f 192 Pfam PF04011 LemA family 12 188 8.4E-71 T 29-03-2018 IPR007156 LemA CB4_RS00470 440d895a0cb46cd23445893f4cc1e74f 192 Gene3D G3DSA:1.20.1440.20 18 188 3.1E-62 T 29-03-2018 CB4_RS07515 ecefe61e73920dbdc47830c3bf813a90 331 Gene3D G3DSA:3.40.50.300 110 328 6.7E-65 T 29-03-2018 CB4_RS07515 ecefe61e73920dbdc47830c3bf813a90 331 ProSitePatterns PS00211 ABC transporters family signature. 248 262 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS07515 ecefe61e73920dbdc47830c3bf813a90 331 SMART SM00382 142 324 1.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS07515 ecefe61e73920dbdc47830c3bf813a90 331 SUPERFAMILY SSF52540 111 327 4.61E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07515 ecefe61e73920dbdc47830c3bf813a90 331 Pfam PF00005 ABC transporter 134 276 1.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS11330 633d153e7985ca735e9b02878ad47028 351 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 131 257 2.7E-7 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CB4_RS11330 633d153e7985ca735e9b02878ad47028 351 SUPERFAMILY SSF52402 26 120 1.47E-16 T 29-03-2018 CB4_RS11330 633d153e7985ca735e9b02878ad47028 351 SUPERFAMILY SSF52402 151 253 1.47E-16 T 29-03-2018 CB4_RS11330 633d153e7985ca735e9b02878ad47028 351 Gene3D G3DSA:3.40.50.620 18 304 1.2E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS17145 1f75e8af5e68cc3fc22a40c3c4932e3c 104 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 26 99 9.4E-10 T 29-03-2018 CB4_RS17145 1f75e8af5e68cc3fc22a40c3c4932e3c 104 PIRSF PIRSF036548 10 104 5.2E-20 T 29-03-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 CB4_RS17145 1f75e8af5e68cc3fc22a40c3c4932e3c 104 Gene3D G3DSA:3.30.70.20 74 100 0.0022 T 29-03-2018 CB4_RS17145 1f75e8af5e68cc3fc22a40c3c4932e3c 104 Gene3D G3DSA:3.30.70.20 27 73 1.4E-4 T 29-03-2018 CB4_RS17145 1f75e8af5e68cc3fc22a40c3c4932e3c 104 SUPERFAMILY SSF54862 37 101 3.22E-15 T 29-03-2018 CB4_RS17145 1f75e8af5e68cc3fc22a40c3c4932e3c 104 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 73 84 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 Gene3D G3DSA:3.30.930.10 231 533 5.6E-124 T 29-03-2018 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 Gene3D G3DSA:3.40.50.800 534 639 9.3E-27 T 29-03-2018 IPR004154 Anticodon-binding CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 SMART SM00863 173 222 3.9E-26 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 323 530 3.9E-39 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 SUPERFAMILY SSF55186 65 244 2.75E-64 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 SUPERFAMILY SSF52954 532 635 1.51E-31 T 29-03-2018 IPR004154 Anticodon-binding CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 Gene3D G3DSA:3.30.980.10 69 230 2.5E-47 T 29-03-2018 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 466 494 5.6E-52 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 332 360 5.6E-52 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 536 548 5.6E-52 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 365 388 5.6E-52 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 509 522 5.6E-52 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 Gene3D G3DSA:3.10.20.30 1 64 1.3E-18 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 Pfam PF02824 TGS domain 5 63 6.3E-12 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 68 636 34.956 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 173 222 1.5E-16 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 SUPERFAMILY SSF55681 246 527 4.38E-96 T 29-03-2018 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 SUPERFAMILY SSF81271 5 63 2.11E-15 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 Pfam PF03129 Anticodon binding domain 543 631 2.1E-21 T 29-03-2018 IPR004154 Anticodon-binding CB4_RS18275 23767d4252985e2d0eb5bf6dc2160224 639 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 74 632 2.5E-230 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CB4_RS01520 dff627bcf28e76bf96c99efb0aa09d51 90 Pfam PF06257 Biofilm formation stimulator VEG 4 75 3.1E-32 T 29-03-2018 IPR009366 Protein Veg GO:0042710 CB4_RS01520 dff627bcf28e76bf96c99efb0aa09d51 90 PIRSF PIRSF037257 1 86 3.1E-36 T 29-03-2018 IPR009366 Protein Veg GO:0042710 CB4_RS01520 dff627bcf28e76bf96c99efb0aa09d51 90 Gene3D G3DSA:2.30.30.100 3 77 4.6E-33 T 29-03-2018 CB4_RS07170 7092b3bda7fbc090f3d5a6f9f5f4e87a 546 Pfam PF00501 AMP-binding enzyme 14 445 7.2E-114 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS07170 7092b3bda7fbc090f3d5a6f9f5f4e87a 546 Gene3D G3DSA:2.30.38.10 354 437 3.8E-29 T 29-03-2018 CB4_RS07170 7092b3bda7fbc090f3d5a6f9f5f4e87a 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 529 9.8E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS07170 7092b3bda7fbc090f3d5a6f9f5f4e87a 546 Gene3D G3DSA:3.30.300.30 438 540 9.4E-28 T 29-03-2018 CB4_RS07170 7092b3bda7fbc090f3d5a6f9f5f4e87a 546 Gene3D G3DSA:3.40.50.980 4 200 8.3E-39 T 29-03-2018 CB4_RS07170 7092b3bda7fbc090f3d5a6f9f5f4e87a 546 Gene3D G3DSA:3.40.50.980 201 353 6.1E-54 T 29-03-2018 CB4_RS07170 7092b3bda7fbc090f3d5a6f9f5f4e87a 546 SUPERFAMILY SSF56801 7 541 1.7E-158 T 29-03-2018 CB4_RS07170 7092b3bda7fbc090f3d5a6f9f5f4e87a 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS13080 ab83d512248e2ce796525d197b12f82c 138 Pfam PF06146 Phosphate-starvation-inducible E 62 127 1.8E-12 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like CB4_RS13080 ab83d512248e2ce796525d197b12f82c 138 PIRSF PIRSF029598 9 138 1.1E-29 T 29-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 CB4_RS20260 7dd92d8d3be21832fc7f62c956b13afd 132 Gene3D G3DSA:3.30.750.24 7 121 4.4E-13 T 29-03-2018 IPR002645 STAS domain CB4_RS20260 7dd92d8d3be21832fc7f62c956b13afd 132 SUPERFAMILY SSF52091 13 120 1.59E-17 T 29-03-2018 IPR002645 STAS domain CB4_RS20260 7dd92d8d3be21832fc7f62c956b13afd 132 Pfam PF01740 STAS domain 24 114 3.9E-9 T 29-03-2018 IPR002645 STAS domain CB4_RS14755 8ee50a2e62bb00e8f62ec3e9acf465f1 245 SUPERFAMILY SSF56281 1 245 3.8E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS14755 8ee50a2e62bb00e8f62ec3e9acf465f1 245 SMART SM00849 18 202 3.8E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS14755 8ee50a2e62bb00e8f62ec3e9acf465f1 245 Gene3D G3DSA:3.60.15.10 3 245 2.0E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS14755 8ee50a2e62bb00e8f62ec3e9acf465f1 245 Pfam PF12706 Beta-lactamase superfamily domain 31 211 9.4E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS00435 00203775cbb8bd2a218a2291e2d651e9 395 Gene3D G3DSA:3.40.640.10 13 257 2.4E-55 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS00435 00203775cbb8bd2a218a2291e2d651e9 395 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 199 213 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS00435 00203775cbb8bd2a218a2291e2d651e9 395 Gene3D G3DSA:3.90.1150.10 258 393 3.6E-49 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS00435 00203775cbb8bd2a218a2291e2d651e9 395 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 17 388 3.8E-149 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS00435 00203775cbb8bd2a218a2291e2d651e9 395 SUPERFAMILY SSF53383 16 388 4.49E-118 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS00435 00203775cbb8bd2a218a2291e2d651e9 395 PIRSF PIRSF001434 5 392 5.4E-149 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS02840 2c3830e14fa26125d2ba350269663c95 427 Gene3D G3DSA:3.20.20.70 173 424 9.3E-20 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS02840 2c3830e14fa26125d2ba350269663c95 427 SUPERFAMILY SSF102114 179 390 4.97E-17 T 29-03-2018 CB4_RS02840 2c3830e14fa26125d2ba350269663c95 427 Pfam PF04055 Radical SAM superfamily 181 351 1.2E-9 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS07590 40fa6768d330d1b33190b24a31845077 162 Gene3D G3DSA:3.10.129.10 28 160 1.9E-33 T 29-03-2018 CB4_RS07590 40fa6768d330d1b33190b24a31845077 162 Pfam PF03061 Thioesterase superfamily 76 149 1.4E-19 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS07590 40fa6768d330d1b33190b24a31845077 162 SUPERFAMILY SSF54637 26 156 3.81E-32 T 29-03-2018 IPR029069 HotDog domain CB4_RS07590 40fa6768d330d1b33190b24a31845077 162 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 47 154 4.4E-23 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CB4_RS08515 162f1a44aef98948d633b6b069c63e4c 292 Gene3D G3DSA:3.40.50.300 61 223 4.7E-29 T 29-03-2018 CB4_RS08515 162f1a44aef98948d633b6b069c63e4c 292 Pfam PF03193 RsgA GTPase 58 223 1.7E-61 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CB4_RS08515 162f1a44aef98948d633b6b069c63e4c 292 SUPERFAMILY SSF50249 1 61 4.28E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS08515 162f1a44aef98948d633b6b069c63e4c 292 Gene3D G3DSA:2.40.50.140 1 60 1.1E-21 T 29-03-2018 CB4_RS08515 162f1a44aef98948d633b6b069c63e4c 292 Pfam PF16745 RsgA N-terminal domain 3 50 4.4E-20 T 29-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CB4_RS08515 162f1a44aef98948d633b6b069c63e4c 292 Gene3D G3DSA:1.10.40.50 228 292 5.6E-22 T 29-03-2018 CB4_RS08515 162f1a44aef98948d633b6b069c63e4c 292 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 282 3.3E-80 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CB4_RS08515 162f1a44aef98948d633b6b069c63e4c 292 SUPERFAMILY SSF52540 64 290 4.1E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08515 162f1a44aef98948d633b6b069c63e4c 292 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 289 38.74 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CB4_RS20450 036ab8956c16f892e9482eea9ee87ad5 163 Pfam PF00994 Probable molybdopterin binding domain 5 146 4.1E-26 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS20450 036ab8956c16f892e9482eea9ee87ad5 163 Gene3D G3DSA:3.40.980.10 1 163 2.6E-30 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS20450 036ab8956c16f892e9482eea9ee87ad5 163 SMART SM00852 5 150 1.2E-19 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS20450 036ab8956c16f892e9482eea9ee87ad5 163 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 66 79 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CB4_RS20450 036ab8956c16f892e9482eea9ee87ad5 163 SUPERFAMILY SSF53218 2 156 1.44E-33 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS20450 036ab8956c16f892e9482eea9ee87ad5 163 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 144 2.0E-26 T 29-03-2018 IPR001453 MoaB/Mog domain CB4_RS18635 84216eda1b98cda4034394783859ee9d 519 Gene3D G3DSA:3.30.390.10 188 271 0.073 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS18635 84216eda1b98cda4034394783859ee9d 519 Gene3D G3DSA:3.30.390.10 294 373 1.9E-4 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CB4_RS18635 84216eda1b98cda4034394783859ee9d 519 ProSitePatterns PS00018 EF-hand calcium-binding domain. 494 506 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site CB4_RS18635 84216eda1b98cda4034394783859ee9d 519 Gene3D G3DSA:2.60.40.1080 374 459 9.3E-14 T 29-03-2018 CB4_RS18635 84216eda1b98cda4034394783859ee9d 519 SUPERFAMILY SSF49373 385 457 8.63E-7 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS18635 84216eda1b98cda4034394783859ee9d 519 Pfam PF13753 Putative flagellar system-associated repeat 295 338 3.9E-5 T 29-03-2018 IPR028059 Putative flagellar system-associated repeat CB4_RS09905 d4fb54363046ad60ec352cf44ca4f060 165 SMART SM00347 47 147 8.0E-26 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09905 d4fb54363046ad60ec352cf44ca4f060 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 1.3E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09905 d4fb54363046ad60ec352cf44ca4f060 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 1.3E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09905 d4fb54363046ad60ec352cf44ca4f060 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 103 1.3E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09905 d4fb54363046ad60ec352cf44ca4f060 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 87 1.3E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09905 d4fb54363046ad60ec352cf44ca4f060 165 Pfam PF01047 MarR family 54 112 3.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS09905 d4fb54363046ad60ec352cf44ca4f060 165 SUPERFAMILY SSF46785 27 163 2.13E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09905 d4fb54363046ad60ec352cf44ca4f060 165 Gene3D G3DSA:1.10.10.10 15 164 2.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09905 d4fb54363046ad60ec352cf44ca4f060 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 86 120 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CB4_RS04240 a70000525cd2fffa75f3e26fb0522c32 400 Pfam PF00202 Aminotransferase class-III 18 398 2.2E-130 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS04240 a70000525cd2fffa75f3e26fb0522c32 400 Gene3D G3DSA:3.40.640.10 178 296 5.8E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS04240 a70000525cd2fffa75f3e26fb0522c32 400 Gene3D G3DSA:3.90.1150.10 297 400 1.8E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS04240 a70000525cd2fffa75f3e26fb0522c32 400 SUPERFAMILY SSF53383 6 399 7.43E-125 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS04240 a70000525cd2fffa75f3e26fb0522c32 400 Hamap MF_01689 Ornithine aminotransferase [rocD]. 7 399 64.227 T 29-03-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 CB4_RS04240 a70000525cd2fffa75f3e26fb0522c32 400 PIRSF PIRSF000521 3 162 1.5E-7 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS04240 a70000525cd2fffa75f3e26fb0522c32 400 PIRSF PIRSF000521 178 400 2.9E-34 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS04240 a70000525cd2fffa75f3e26fb0522c32 400 Gene3D G3DSA:3.90.1150.10 3 177 1.1E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS04240 a70000525cd2fffa75f3e26fb0522c32 400 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 8 398 4.6E-166 T 29-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CB4_RS04240 a70000525cd2fffa75f3e26fb0522c32 400 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 226 263 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 Gene3D G3DSA:1.10.287.990 44 109 5.8E-24 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 329 1.0E-70 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.1E-80 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 1.1E-80 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.1E-80 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 1.1E-80 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 1.1E-80 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 1.1E-80 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.1E-80 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.1E-80 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 1.1E-80 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 466 5.0E-175 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 Gene3D G3DSA:3.50.50.60 118 253 3.5E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PIRSF PIRSF000350 2 469 2.3E-100 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 1.8E-43 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 1.8E-43 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.8E-43 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.8E-43 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 1.8E-43 T 29-03-2018 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 Gene3D G3DSA:3.30.390.30 363 462 3.4E-41 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 Gene3D G3DSA:3.50.50.60 271 362 6.8E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 SUPERFAMILY SSF51905 7 338 2.5E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 SUPERFAMILY SSF55424 344 466 3.09E-44 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 3.8E-40 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CB4_RS06505 48ea9b940a741a408d3c79f73c87424c 470 Gene3D G3DSA:3.40.50.720 4 43 4.2E-4 T 29-03-2018 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 Pfam PF00330 Aconitase family (aconitate hydratase) 70 571 4.0E-178 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 ProSitePatterns PS01244 Aconitase family signature 2. 502 515 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 Gene3D G3DSA:3.40.1060.10 241 373 1.4E-44 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 Gene3D G3DSA:3.30.499.10 36 240 2.5E-74 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 ProSitePatterns PS00450 Aconitase family signature 1. 436 452 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 Gene3D G3DSA:3.20.19.10 662 902 9.4E-92 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 SUPERFAMILY SSF52016 639 899 6.87E-88 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 Gene3D G3DSA:3.30.499.10 374 585 2.2E-65 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 Pfam PF00694 Aconitase C-terminal domain 701 828 6.1E-49 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 PRINTS PR00415 Aconitase family signature 171 179 9.1E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 PRINTS PR00415 Aconitase family signature 204 217 9.1E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 PRINTS PR00415 Aconitase family signature 294 307 9.1E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 PRINTS PR00415 Aconitase family signature 280 293 9.1E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 PRINTS PR00415 Aconitase family signature 374 388 9.1E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 PRINTS PR00415 Aconitase family signature 502 515 9.1E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 PRINTS PR00415 Aconitase family signature 147 160 9.1E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 PRINTS PR00415 Aconitase family signature 218 233 9.1E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 PRINTS PR00415 Aconitase family signature 440 451 9.1E-42 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 900 0.0 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CB4_RS04010 64507a6ca17a083a45a01a3236714d0b 908 SUPERFAMILY SSF53732 5 636 6.15E-224 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 SUPERFAMILY SSF53067 196 370 1.01E-39 T 29-03-2018 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 SMART SM00842 7 194 9.3E-96 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 Pfam PF14450 Cell division protein FtsA 9 187 3.1E-10 T 29-03-2018 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 Pfam PF14450 Cell division protein FtsA 205 367 1.2E-20 T 29-03-2018 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 Gene3D G3DSA:3.30.420.40 262 350 1.6E-17 T 29-03-2018 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 Gene3D G3DSA:3.30.420.40 195 261 5.6E-7 T 29-03-2018 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 Pfam PF02491 SHS2 domain inserted in FTSA 81 160 2.5E-27 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 371 6.0E-122 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 Gene3D G3DSA:3.30.420.40 1 185 1.2E-36 T 29-03-2018 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 425 30.109 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 SUPERFAMILY SSF53067 5 195 8.64E-59 T 29-03-2018 CB4_RS08290 86daaee2bed2f662a909df9e99c41af3 425 PIRSF PIRSF003101 1 425 7.7E-143 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CB4_RS16150 d9ad7b4193765084e7448c7bf3ed6520 364 SUPERFAMILY SSF52540 7 244 5.6E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS16150 d9ad7b4193765084e7448c7bf3ed6520 364 Gene3D G3DSA:3.40.50.300 2 241 3.9E-76 T 29-03-2018 CB4_RS16150 d9ad7b4193765084e7448c7bf3ed6520 364 Gene3D G3DSA:2.40.50.100 242 293 0.0088 T 29-03-2018 CB4_RS16150 d9ad7b4193765084e7448c7bf3ed6520 364 Pfam PF08402 TOBE domain 281 355 1.0E-11 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CB4_RS16150 d9ad7b4193765084e7448c7bf3ed6520 364 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS16150 d9ad7b4193765084e7448c7bf3ed6520 364 SUPERFAMILY SSF50331 239 356 2.32E-13 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CB4_RS16150 d9ad7b4193765084e7448c7bf3ed6520 364 SMART SM00382 31 214 3.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS16150 d9ad7b4193765084e7448c7bf3ed6520 364 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 37 351 6.1E-116 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CB4_RS16150 d9ad7b4193765084e7448c7bf3ed6520 364 Pfam PF00005 ABC transporter 23 164 1.1E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS16150 d9ad7b4193765084e7448c7bf3ed6520 364 Gene3D G3DSA:2.40.50.140 294 349 7.0E-7 T 29-03-2018 CB4_RS06650 308555362dcafca8bf183d523d7053a0 371 Pfam PF00557 Metallopeptidase family M24 151 353 4.3E-67 T 29-03-2018 IPR000994 Peptidase M24 CB4_RS06650 308555362dcafca8bf183d523d7053a0 371 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 299 311 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CB4_RS06650 308555362dcafca8bf183d523d7053a0 371 SUPERFAMILY SSF53092 3 141 3.66E-24 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CB4_RS06650 308555362dcafca8bf183d523d7053a0 371 SUPERFAMILY SSF55920 140 367 3.79E-81 T 29-03-2018 IPR000994 Peptidase M24 CB4_RS06650 308555362dcafca8bf183d523d7053a0 371 PRINTS PR00599 Methionine aminopeptidase-1 signature 201 214 1.5E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS06650 308555362dcafca8bf183d523d7053a0 371 PRINTS PR00599 Methionine aminopeptidase-1 signature 223 239 1.5E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS06650 308555362dcafca8bf183d523d7053a0 371 PRINTS PR00599 Methionine aminopeptidase-1 signature 321 333 1.5E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS06650 308555362dcafca8bf183d523d7053a0 371 Gene3D G3DSA:3.90.230.10 142 371 1.3E-80 T 29-03-2018 CB4_RS06650 308555362dcafca8bf183d523d7053a0 371 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 142 3.8E-18 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CB4_RS06650 308555362dcafca8bf183d523d7053a0 371 Gene3D G3DSA:3.40.350.10 5 141 4.6E-20 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CB4_RS10390 180316ad22718e64e7ec450da26c49b4 247 Gene3D G3DSA:3.10.350.10 183 238 1.8E-15 T 29-03-2018 CB4_RS10390 180316ad22718e64e7ec450da26c49b4 247 SMART SM00257 189 233 1.0E-12 T 29-03-2018 IPR018392 LysM domain CB4_RS10390 180316ad22718e64e7ec450da26c49b4 247 Gene3D G3DSA:2.40.50.90 30 146 3.8E-16 T 29-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CB4_RS10390 180316ad22718e64e7ec450da26c49b4 247 Pfam PF00565 Staphylococcal nuclease homologue 75 142 6.2E-12 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CB4_RS10390 180316ad22718e64e7ec450da26c49b4 247 SMART SM00318 42 143 2.0E-5 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CB4_RS10390 180316ad22718e64e7ec450da26c49b4 247 Pfam PF01476 LysM domain 190 233 1.4E-13 T 29-03-2018 IPR018392 LysM domain CB4_RS10390 180316ad22718e64e7ec450da26c49b4 247 SUPERFAMILY SSF54106 188 233 1.57E-10 T 29-03-2018 IPR018392 LysM domain CB4_RS10390 180316ad22718e64e7ec450da26c49b4 247 ProSitePatterns PS01284 Thermonuclease family signature 2. 100 110 - T 29-03-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 CB4_RS10390 180316ad22718e64e7ec450da26c49b4 247 SUPERFAMILY SSF50199 41 144 1.7E-18 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CB4_RS19980 3e6c8e05de70e736f12b0e7399604d82 367 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 244 316 1.8E-14 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS19980 3e6c8e05de70e736f12b0e7399604d82 367 Gene3D G3DSA:1.20.1270.60 73 303 3.0E-4 T 29-03-2018 CB4_RS19980 3e6c8e05de70e736f12b0e7399604d82 367 Pfam PF07282 Putative transposase DNA-binding domain 289 359 2.0E-25 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS19980 3e6c8e05de70e736f12b0e7399604d82 367 Pfam PF12323 Helix-turn-helix domain 1 48 1.8E-19 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CB4_RS19980 3e6c8e05de70e736f12b0e7399604d82 367 Pfam PF01385 Probable transposase 166 275 6.5E-25 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS06525 496832ace92f59260320d6d6106889fd 172 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 35 137 1.7E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS06525 496832ace92f59260320d6d6106889fd 172 Gene3D G3DSA:3.40.50.1000 16 155 1.4E-23 T 29-03-2018 IPR023214 HAD-like domain CB4_RS06525 496832ace92f59260320d6d6106889fd 172 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 29 139 7.1E-23 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CB4_RS06525 496832ace92f59260320d6d6106889fd 172 SUPERFAMILY SSF56784 11 147 6.7E-25 T 29-03-2018 IPR023214 HAD-like domain CB4_RS06525 496832ace92f59260320d6d6106889fd 172 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 5 167 6.9E-55 T 29-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like CB4_RS06525 496832ace92f59260320d6d6106889fd 172 Pfam PF09419 Mitochondrial PGP phosphatase 4 136 1.6E-12 T 29-03-2018 IPR027706 Mitochondrial PGP phosphatase KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CB4_RS20160 63c7128b7a70c3daa555a3753a9d6b5e 444 PIRSF PIRSF000139 21 444 3.0E-131 T 29-03-2018 CB4_RS20160 63c7128b7a70c3daa555a3753a9d6b5e 444 Pfam PF13183 4Fe-4S dicluster domain 30 98 1.6E-13 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS20160 63c7128b7a70c3daa555a3753a9d6b5e 444 Gene3D G3DSA:1.10.1060.10 7 121 8.6E-18 T 29-03-2018 CB4_RS20160 63c7128b7a70c3daa555a3753a9d6b5e 444 SUPERFAMILY SSF46548 29 110 3.35E-18 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CB4_RS20160 63c7128b7a70c3daa555a3753a9d6b5e 444 Gene3D G3DSA:3.40.50.720 221 411 4.3E-4 T 29-03-2018 CB4_RS20160 63c7128b7a70c3daa555a3753a9d6b5e 444 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS20160 63c7128b7a70c3daa555a3753a9d6b5e 444 Pfam PF02754 Cysteine-rich domain 206 288 1.8E-17 T 29-03-2018 IPR004017 Cysteine-rich domain CB4_RS20160 63c7128b7a70c3daa555a3753a9d6b5e 444 Pfam PF02754 Cysteine-rich domain 334 419 1.4E-17 T 29-03-2018 IPR004017 Cysteine-rich domain CB4_RS13655 14b3f8ed39bb84de0e8dd3414353a038 117 SUPERFAMILY SSF54593 6 114 1.17E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS13655 14b3f8ed39bb84de0e8dd3414353a038 117 Gene3D G3DSA:3.10.180.10 1 117 1.7E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS13655 14b3f8ed39bb84de0e8dd3414353a038 117 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 110 6.9E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CB4_RS14555 bfdf3ee4f69af29deefb0ca9ec688f9f 163 Pfam PF13787 Protein of unknown function with HXXEE motif 30 121 3.5E-11 T 29-03-2018 IPR025671 Protein of unknown function with HXXEE motif CB4_RS13115 9db04a88ebe40d3eb43cf4ec965bebeb 294 SUPERFAMILY SSF161098 72 259 9.94E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS13115 9db04a88ebe40d3eb43cf4ec965bebeb 294 Gene3D G3DSA:1.10.3720.10 4 267 4.1E-40 T 29-03-2018 CB4_RS13115 9db04a88ebe40d3eb43cf4ec965bebeb 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 269 1.9E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS11370 482cd228e0d43214380e3b11dc323be0 153 Gene3D G3DSA:3.40.140.10 25 152 1.0E-46 T 29-03-2018 CB4_RS11370 482cd228e0d43214380e3b11dc323be0 153 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 101 106 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CB4_RS11370 482cd228e0d43214380e3b11dc323be0 153 Pfam PF04002 RadC-like JAB domain 30 150 3.0E-43 T 29-03-2018 IPR025657 RadC-like JAB domain CB4_RS11370 482cd228e0d43214380e3b11dc323be0 153 TIGRFAM TIGR00608 radc: DNA repair protein RadC 24 151 3.9E-40 T 29-03-2018 IPR001405 RadC protein CB4_RS11370 482cd228e0d43214380e3b11dc323be0 153 SUPERFAMILY SSF102712 44 122 3.14E-6 T 29-03-2018 CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 Pfam PF02237 Biotin protein ligase C terminal domain 277 322 4.7E-12 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 Gene3D G3DSA:1.10.10.10 2 62 4.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 Pfam PF03099 Biotin/lipoate A/B protein ligase family 90 212 1.1E-19 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 6 324 38.17 T 29-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 Gene3D G3DSA:2.30.30.100 278 321 5.5E-13 T 29-03-2018 CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 Gene3D G3DSA:3.30.930.10 64 276 4.4E-70 T 29-03-2018 CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 SUPERFAMILY SSF46785 5 59 8.53E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 Pfam PF08279 HTH domain 5 58 1.3E-15 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 SUPERFAMILY SSF50037 279 323 3.25E-8 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 83 322 2.8E-68 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CB4_RS14975 026c6409869f592a89f9be96dd86d6de 325 SUPERFAMILY SSF55681 71 274 9.94E-62 T 29-03-2018 CB4_RS04875 11b53f8bce4c6c92fff3511c32a92c86 184 SUPERFAMILY SSF160387 45 155 1.23E-19 T 29-03-2018 CB4_RS04875 11b53f8bce4c6c92fff3511c32a92c86 184 Pfam PF05573 NosL 11 140 1.9E-19 T 29-03-2018 IPR008719 Nitrous oxide reductase accessory protein NosL CB4_RS03640 a33a603a4285016c07fdfea2f770282a 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 5 302 1.2E-117 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CB4_RS03640 a33a603a4285016c07fdfea2f770282a 310 Gene3D G3DSA:3.40.1390.20 3 132 2.5E-40 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CB4_RS03640 a33a603a4285016c07fdfea2f770282a 310 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 3.2E-76 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CB4_RS03640 a33a603a4285016c07fdfea2f770282a 310 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 41.162 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CB4_RS03640 a33a603a4285016c07fdfea2f770282a 310 Pfam PF02603 HPr Serine kinase N terminus 6 127 2.1E-35 T 29-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CB4_RS03640 a33a603a4285016c07fdfea2f770282a 310 SUPERFAMILY SSF53795 132 298 2.93E-40 T 29-03-2018 CB4_RS03640 a33a603a4285016c07fdfea2f770282a 310 SUPERFAMILY SSF75138 2 131 5.49E-35 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CB4_RS03640 a33a603a4285016c07fdfea2f770282a 310 Gene3D G3DSA:3.40.50.300 134 307 1.6E-45 T 29-03-2018 CB4_RS11005 140224a91610842313de3530b6a41c95 192 SUPERFAMILY SSF50199 39 180 4.32E-34 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CB4_RS11005 140224a91610842313de3530b6a41c95 192 Gene3D G3DSA:2.40.50.90 37 184 1.1E-34 T 29-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CB4_RS11005 140224a91610842313de3530b6a41c95 192 Pfam PF00565 Staphylococcal nuclease homologue 69 180 8.2E-22 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CB4_RS11005 140224a91610842313de3530b6a41c95 192 SMART SM00318 44 180 1.4E-27 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CB4_RS15140 7397cfb9f7595bb370c4cd3645cf0ad8 388 ProSitePatterns PS00788 Chorismate synthase signature 2. 130 146 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CB4_RS15140 7397cfb9f7595bb370c4cd3645cf0ad8 388 PIRSF PIRSF001456 1 380 6.5E-132 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CB4_RS15140 7397cfb9f7595bb370c4cd3645cf0ad8 388 SUPERFAMILY SSF103263 1 387 4.06E-147 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CB4_RS15140 7397cfb9f7595bb370c4cd3645cf0ad8 388 Hamap MF_00300 Chorismate synthase [aroC]. 1 370 36.588 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CB4_RS15140 7397cfb9f7595bb370c4cd3645cf0ad8 388 Pfam PF01264 Chorismate synthase 1 362 9.2E-127 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CB4_RS15140 7397cfb9f7595bb370c4cd3645cf0ad8 388 TIGRFAM TIGR00033 aroC: chorismate synthase 1 368 1.4E-132 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CB4_RS15140 7397cfb9f7595bb370c4cd3645cf0ad8 388 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CB4_RS15140 7397cfb9f7595bb370c4cd3645cf0ad8 388 ProSitePatterns PS00789 Chorismate synthase signature 3. 337 353 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CB4_RS15140 7397cfb9f7595bb370c4cd3645cf0ad8 388 Gene3D G3DSA:3.60.150.10 1 388 1.4E-144 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CB4_RS11355 5a465c159cff770957282d91df5c6443 139 Gene3D G3DSA:1.10.10.60 92 139 4.8E-9 T 29-03-2018 CB4_RS11355 5a465c159cff770957282d91df5c6443 139 Pfam PF13936 Helix-turn-helix domain 99 129 2.4E-6 T 29-03-2018 IPR025246 Transposase IS30-like HTH domain CB4_RS14230 08edf6b68df0f14e94c18f68abe4208a 97 Gene3D G3DSA:1.20.1260.10 1 69 9.0E-7 T 29-03-2018 IPR012347 Ferritin-related CB4_RS14230 08edf6b68df0f14e94c18f68abe4208a 97 Pfam PF07875 Coat F domain 11 72 5.4E-14 T 29-03-2018 IPR012851 Spore coat protein CotF-like CB4_RS09605 db9067a20108e16dc97d6e5068a40efb 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 217 229 3.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS09605 db9067a20108e16dc97d6e5068a40efb 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 201 217 3.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS09605 db9067a20108e16dc97d6e5068a40efb 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 201 3.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS09605 db9067a20108e16dc97d6e5068a40efb 246 SMART SM00421 184 241 9.0E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS09605 db9067a20108e16dc97d6e5068a40efb 246 Gene3D G3DSA:1.10.10.10 187 244 2.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09605 db9067a20108e16dc97d6e5068a40efb 246 SUPERFAMILY SSF55781 10 170 2.4E-10 T 29-03-2018 IPR029016 GAF domain-like CB4_RS09605 db9067a20108e16dc97d6e5068a40efb 246 SUPERFAMILY SSF46894 183 240 2.11E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS09605 db9067a20108e16dc97d6e5068a40efb 246 Pfam PF00196 Bacterial regulatory proteins, luxR family 186 238 5.2E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS09605 db9067a20108e16dc97d6e5068a40efb 246 Gene3D G3DSA:3.30.450.40 11 176 4.3E-9 T 29-03-2018 IPR029016 GAF domain-like CB4_RS09605 db9067a20108e16dc97d6e5068a40efb 246 ProSitePatterns PS00622 LuxR-type HTH domain signature. 201 228 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS17605 0495183abb89669f023a8bd681d4a94c 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CB4_RS17605 0495183abb89669f023a8bd681d4a94c 507 Gene3D G3DSA:3.40.309.10 271 465 4.7E-74 T 29-03-2018 CB4_RS17605 0495183abb89669f023a8bd681d4a94c 507 Gene3D G3DSA:3.40.605.10 2 270 7.1E-94 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS17605 0495183abb89669f023a8bd681d4a94c 507 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 10 493 1.6E-231 T 29-03-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 CB4_RS17605 0495183abb89669f023a8bd681d4a94c 507 Pfam PF00171 Aldehyde dehydrogenase family 24 479 4.5E-172 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS17605 0495183abb89669f023a8bd681d4a94c 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CB4_RS17605 0495183abb89669f023a8bd681d4a94c 507 SUPERFAMILY SSF53720 6 485 2.36E-165 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS02670 c4d9a343d499a7ce3ee243f145b98734 240 Gene3D G3DSA:3.20.20.190 2 240 3.1E-66 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CB4_RS02670 c4d9a343d499a7ce3ee243f145b98734 240 SUPERFAMILY SSF51695 3 238 5.76E-68 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CB4_RS02670 c4d9a343d499a7ce3ee243f145b98734 240 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 222 1.4E-31 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CB4_RS10600 cbbd1a5b8e1f071d95f4c32d180e4c8b 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 373 3.1E-113 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CB4_RS10600 cbbd1a5b8e1f071d95f4c32d180e4c8b 382 Gene3D G3DSA:3.40.50.1970 9 181 1.1E-43 T 29-03-2018 CB4_RS10600 cbbd1a5b8e1f071d95f4c32d180e4c8b 382 Gene3D G3DSA:1.20.1090.10 184 382 1.2E-54 T 29-03-2018 CB4_RS10600 cbbd1a5b8e1f071d95f4c32d180e4c8b 382 SUPERFAMILY SSF56796 5 380 4.06E-116 T 29-03-2018 CB4_RS05975 fd44e2a70d90cecd03249aeb81115eec 116 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 1 112 5.1E-29 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane CB4_RS05975 fd44e2a70d90cecd03249aeb81115eec 116 Pfam PF12670 Protein of unknown function (DUF3792) 1 109 3.9E-23 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane CB4_RS13060 6a0b55f459f3976aaef6d71a0384b1c7 212 Gene3D G3DSA:3.90.79.10 1 165 1.8E-16 T 29-03-2018 CB4_RS13060 6a0b55f459f3976aaef6d71a0384b1c7 212 SUPERFAMILY SSF55811 3 154 1.49E-21 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CB4_RS13060 6a0b55f459f3976aaef6d71a0384b1c7 212 Pfam PF00293 NUDIX domain 37 148 2.1E-7 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF00395 S-layer homology domain 1042 1086 2.5E-14 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF00395 S-layer homology domain 1105 1147 2.6E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF00395 S-layer homology domain 983 1025 6.3E-16 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 SUPERFAMILY SSF101898 21 191 1.07E-32 T 29-03-2018 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 SUPERFAMILY SSF101898 380 611 3.92E-42 T 29-03-2018 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Gene3D G3DSA:2.120.10.30 337 421 1.2E-18 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Gene3D G3DSA:2.120.10.30 515 839 2.2E-15 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Gene3D G3DSA:2.120.10.30 422 514 3.8E-23 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Gene3D G3DSA:2.120.10.30 142 237 4.4E-23 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Gene3D G3DSA:2.120.10.30 238 336 2.9E-21 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Gene3D G3DSA:2.120.10.30 51 141 1.2E-22 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF12733 Cadherin-like beta sandwich domain 615 706 3.3E-15 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF12733 Cadherin-like beta sandwich domain 719 806 4.1E-17 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 SUPERFAMILY SSF101898 150 413 4.97E-53 T 29-03-2018 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF01436 NHL repeat 151 178 1.6E-9 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF01436 NHL repeat 476 503 1.6E-7 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF01436 NHL repeat 291 318 1.6E-9 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF01436 NHL repeat 57 84 2.1E-9 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF01436 NHL repeat 523 550 1.6E-7 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF01436 NHL repeat 198 225 1.0E-9 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF01436 NHL repeat 104 131 3.6E-8 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF01436 NHL repeat 429 456 1.2E-9 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS19940 c748369afd26cb3aa315e42bd0fe6d60 1160 Pfam PF01436 NHL repeat 382 409 6.6E-8 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS06180 e6622df0b3be359c9de093e5b2c3c861 237 SUPERFAMILY SSF55729 73 221 6.28E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS06180 e6622df0b3be359c9de093e5b2c3c861 237 Pfam PF00583 Acetyltransferase (GNAT) family 105 209 2.2E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS06180 e6622df0b3be359c9de093e5b2c3c861 237 Gene3D G3DSA:3.40.630.30 73 223 2.2E-15 T 29-03-2018 CB4_RS04900 474da9d63566c8549e07acf7949df1f7 304 Pfam PF00892 EamA-like transporter family 4 134 1.2E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS04900 474da9d63566c8549e07acf7949df1f7 304 Pfam PF00892 EamA-like transporter family 150 288 1.3E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS04900 474da9d63566c8549e07acf7949df1f7 304 SUPERFAMILY SSF103481 36 137 4.71E-13 T 29-03-2018 CB4_RS04900 474da9d63566c8549e07acf7949df1f7 304 SUPERFAMILY SSF103481 186 291 4.45E-14 T 29-03-2018 CB4_RS04660 903e1a390bb6905ed9c6e21dbe854780 150 Pfam PF00578 AhpC/TSA family 5 125 8.3E-15 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS04660 903e1a390bb6905ed9c6e21dbe854780 150 SUPERFAMILY SSF52833 2 140 5.38E-30 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS04660 903e1a390bb6905ed9c6e21dbe854780 150 Gene3D G3DSA:3.40.30.10 1 139 5.6E-24 T 29-03-2018 CB4_RS04335 2437c1dc9701fe6a5deb923f264c755f 312 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 32.013 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CB4_RS04335 2437c1dc9701fe6a5deb923f264c755f 312 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 286 1.2E-91 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CB4_RS04335 2437c1dc9701fe6a5deb923f264c755f 312 Pfam PF02401 LytB protein 4 284 7.3E-80 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CB4_RS19725 b11155fd398f73d731cfe324381889fa 73 Pfam PF06569 Protein of unknown function (DUF1128) 3 73 1.6E-33 T 29-03-2018 IPR009507 Protein of unknown function UPF0435 CB4_RS19725 b11155fd398f73d731cfe324381889fa 73 Hamap MF_00829 UPF0435 protein . 6 73 19.796 T 29-03-2018 IPR009507 Protein of unknown function UPF0435 CB4_RS11965 38bb5d43095ff1b2253e83e276b81cc1 99 Pfam PF10850 Protein of unknown function (DUF2653) 1 88 1.0E-30 T 29-03-2018 IPR020516 Uncharacterised protein family YxcD CB4_RS11965 38bb5d43095ff1b2253e83e276b81cc1 99 ProDom PD068665 YXCD 1 93 7.0E-23 T 29-03-2018 IPR020516 Uncharacterised protein family YxcD CB4_RS04385 0abc7875fc84de66e846a36995662770 270 Gene3D G3DSA:3.40.50.300 1 163 1.6E-12 T 29-03-2018 CB4_RS04385 0abc7875fc84de66e846a36995662770 270 SUPERFAMILY SSF52540 3 107 4.2E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03460 c3ab6f0bb19dde6236cc6df5e6d63435 125 SUPERFAMILY SSF101116 6 122 2.49E-30 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CB4_RS03460 c3ab6f0bb19dde6236cc6df5e6d63435 125 TIGRFAM TIGR00208 fliS: flagellar protein FliS 3 119 4.3E-27 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CB4_RS03460 c3ab6f0bb19dde6236cc6df5e6d63435 125 Pfam PF02561 Flagellar protein FliS 9 119 8.2E-31 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CB4_RS03460 c3ab6f0bb19dde6236cc6df5e6d63435 125 Gene3D G3DSA:1.20.120.340 1 122 5.2E-32 T 29-03-2018 CB4_RS03460 c3ab6f0bb19dde6236cc6df5e6d63435 125 PIRSF PIRSF039090 2 125 2.4E-24 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CB4_RS14070 29f4f839f706d2014f5e430d6aa243dc 178 Gene3D G3DSA:2.30.110.10 5 171 2.6E-33 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS14070 29f4f839f706d2014f5e430d6aa243dc 178 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 13 162 4.5E-26 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CB4_RS14070 29f4f839f706d2014f5e430d6aa243dc 178 SUPERFAMILY SSF50475 4 165 3.93E-45 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS20690 0955cfb5de91c1d433040252827ed458 247 Pfam PF00535 Glycosyl transferase family 2 4 172 4.2E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CB4_RS20690 0955cfb5de91c1d433040252827ed458 247 SUPERFAMILY SSF53448 3 229 3.87E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS20690 0955cfb5de91c1d433040252827ed458 247 Gene3D G3DSA:3.90.550.10 1 241 2.6E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS09070 b0d7d7c889d9271775da971011315c2e 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 139.178 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CB4_RS09070 b0d7d7c889d9271775da971011315c2e 259 PIRSF PIRSF011572 1 257 1.4E-116 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CB4_RS09070 b0d7d7c889d9271775da971011315c2e 259 Pfam PF06018 CodY GAF-like domain 3 178 1.3E-71 T 29-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CB4_RS09070 b0d7d7c889d9271775da971011315c2e 259 Pfam PF08222 CodY helix-turn-helix domain 198 257 7.8E-37 T 29-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CB4_RS09070 b0d7d7c889d9271775da971011315c2e 259 Gene3D G3DSA:3.30.450.40 1 159 5.9E-29 T 29-03-2018 IPR029016 GAF domain-like CB4_RS09070 b0d7d7c889d9271775da971011315c2e 259 SUPERFAMILY SSF46785 167 256 1.57E-41 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09070 b0d7d7c889d9271775da971011315c2e 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 1.5E-115 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CB4_RS09070 b0d7d7c889d9271775da971011315c2e 259 Gene3D G3DSA:1.10.10.10 160 259 2.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15875 a9edd69aaf4c447344c7f57a5bfa9c93 165 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 57 63 - T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CB4_RS15875 a9edd69aaf4c447344c7f57a5bfa9c93 165 SUPERFAMILY SSF50324 4 163 1.24E-60 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CB4_RS15875 a9edd69aaf4c447344c7f57a5bfa9c93 165 Gene3D G3DSA:3.90.80.10 1 165 6.7E-54 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CB4_RS15875 a9edd69aaf4c447344c7f57a5bfa9c93 165 Pfam PF00719 Inorganic pyrophosphatase 10 161 5.7E-55 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CB4_RS15875 a9edd69aaf4c447344c7f57a5bfa9c93 165 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 6 162 35.188 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CB4_RS07315 c3b855d202bd937c94c46a8cc35d8ed9 280 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 34 238 4.6E-43 T 29-03-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 CB4_RS07315 c3b855d202bd937c94c46a8cc35d8ed9 280 Pfam PF02361 Cobalt transport protein 30 242 1.2E-33 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CB4_RS12890 658f93408feba84486df208d46680be2 308 Pfam PF01522 Polysaccharide deacetylase 122 240 7.4E-30 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS12890 658f93408feba84486df208d46680be2 308 SUPERFAMILY SSF88713 122 305 2.37E-55 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS12890 658f93408feba84486df208d46680be2 308 Gene3D G3DSA:3.20.20.370 58 306 8.0E-50 T 29-03-2018 CB4_RS10105 b9273b832208eba16a276df9df7ee307 463 SUPERFAMILY SSF53720 10 447 1.15E-129 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS10105 b9273b832208eba16a276df9df7ee307 463 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 244 255 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CB4_RS10105 b9273b832208eba16a276df9df7ee307 463 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 216 223 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CB4_RS10105 b9273b832208eba16a276df9df7ee307 463 PIRSF PIRSF036492 1 463 1.3E-184 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CB4_RS10105 b9273b832208eba16a276df9df7ee307 463 Gene3D G3DSA:3.40.309.10 236 415 3.2E-66 T 29-03-2018 CB4_RS10105 b9273b832208eba16a276df9df7ee307 463 Pfam PF00171 Aldehyde dehydrogenase family 4 435 1.9E-95 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS10105 b9273b832208eba16a276df9df7ee307 463 Gene3D G3DSA:3.40.605.10 2 235 1.0E-73 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS00735 50b72f80bacbf81c6df078d03c82c7a3 216 Pfam PF01944 Stage II sporulation protein M 20 196 9.5E-31 T 29-03-2018 IPR002798 Stage II sporulation protein M-like CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 SMART SM00091 43 115 0.0026 T 29-03-2018 IPR000014 PAS domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 SUPERFAMILY SSF141868 472 718 1.83E-96 T 29-03-2018 IPR001633 EAL domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 Gene3D G3DSA:3.30.70.270 293 461 5.2E-61 T 29-03-2018 CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 SUPERFAMILY SSF55785 57 156 6.81E-28 T 29-03-2018 IPR000014 PAS domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 SUPERFAMILY SSF55073 299 457 4.32E-51 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 Pfam PF00563 EAL domain 472 706 5.4E-76 T 29-03-2018 IPR001633 EAL domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 SMART SM00267 283 455 3.5E-64 T 29-03-2018 IPR000160 GGDEF domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 291 453 3.5E-43 T 29-03-2018 IPR000160 GGDEF domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 49 166 2.0E-18 T 29-03-2018 IPR000014 PAS domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 SMART SM00052 465 711 8.5E-130 T 29-03-2018 IPR001633 EAL domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 Gene3D G3DSA:3.20.20.450 462 715 1.5E-107 T 29-03-2018 IPR001633 EAL domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 Gene3D G3DSA:3.40.50.10600 44 165 4.6E-29 T 29-03-2018 CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 Pfam PF13426 PAS domain 57 158 7.1E-15 T 29-03-2018 IPR000014 PAS domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 SUPERFAMILY SSF55785 205 292 1.13E-7 T 29-03-2018 IPR000014 PAS domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 Pfam PF00990 Diguanylate cyclase, GGDEF domain 294 450 3.0E-50 T 29-03-2018 IPR000160 GGDEF domain CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 SMART SM00086 117 159 6.1E-5 T 29-03-2018 IPR001610 PAC motif CB4_RS06955 462d9f62e0b6f4e325b68ccde13688e9 724 Gene3D G3DSA:3.30.450.20 171 292 1.5E-8 T 29-03-2018 CB4_RS11720 f346d0ac376bd2e4e2986e604d3a6e49 316 SMART SM00942 219 284 0.0094 T 29-03-2018 IPR014820 Primase, C-terminal 1 CB4_RS11720 f346d0ac376bd2e4e2986e604d3a6e49 316 SUPERFAMILY SSF56747 31 157 5.45E-12 T 29-03-2018 CB4_RS11720 f346d0ac376bd2e4e2986e604d3a6e49 316 Gene3D G3DSA:3.90.920.10 11 185 2.0E-6 T 29-03-2018 CB4_RS19125 5c43e9a0c34f105562eba4b4db03d1ec 376 Pfam PF00395 S-layer homology domain 175 216 1.2E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS19125 5c43e9a0c34f105562eba4b4db03d1ec 376 Pfam PF00395 S-layer homology domain 49 91 1.7E-6 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS19125 5c43e9a0c34f105562eba4b4db03d1ec 376 Pfam PF00395 S-layer homology domain 111 154 8.0E-12 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS00085 10be88e54837e8582c1e3412e1035cc9 394 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 10 379 1.0E-72 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS00085 10be88e54837e8582c1e3412e1035cc9 394 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 219 377 6.4E-22 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS15090 83aae2afb94edb24b7e338e1d982b08f 365 Pfam PF02153 Prephenate dehydrogenase 16 271 7.1E-72 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CB4_RS15090 83aae2afb94edb24b7e338e1d982b08f 365 Gene3D G3DSA:3.30.70.260 295 358 3.8E-7 T 29-03-2018 CB4_RS15090 83aae2afb94edb24b7e338e1d982b08f 365 Gene3D G3DSA:3.40.50.720 2 172 8.0E-27 T 29-03-2018 CB4_RS15090 83aae2afb94edb24b7e338e1d982b08f 365 SUPERFAMILY SSF51735 3 169 3.26E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS15090 83aae2afb94edb24b7e338e1d982b08f 365 SUPERFAMILY SSF55021 292 350 1.21E-8 T 29-03-2018 CB4_RS15090 83aae2afb94edb24b7e338e1d982b08f 365 SUPERFAMILY SSF48179 173 283 1.7E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS15090 83aae2afb94edb24b7e338e1d982b08f 365 Gene3D G3DSA:1.10.3660.10 181 294 2.8E-25 T 29-03-2018 CB4_RS15090 83aae2afb94edb24b7e338e1d982b08f 365 Pfam PF01842 ACT domain 298 334 2.0E-6 T 29-03-2018 IPR002912 ACT domain CB4_RS20335 663f83d182340571e32eb3d5606464cb 399 SUPERFAMILY SSF53822 45 394 6.77E-97 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS20335 663f83d182340571e32eb3d5606464cb 399 Gene3D G3DSA:3.40.50.2300 180 347 2.1E-45 T 29-03-2018 CB4_RS20335 663f83d182340571e32eb3d5606464cb 399 Gene3D G3DSA:3.40.50.2300 30 179 3.7E-25 T 29-03-2018 CB4_RS20335 663f83d182340571e32eb3d5606464cb 399 Pfam PF13458 Periplasmic binding protein 45 390 4.7E-68 T 29-03-2018 IPR028081 Leucine-binding protein domain CB4_RS13680 74c379996b08ca2ffe055518b64ef95b 74 SUPERFAMILY SSF53187 4 74 1.67E-11 T 29-03-2018 CB4_RS13680 74c379996b08ca2ffe055518b64ef95b 74 Pfam PF01546 Peptidase family M20/M25/M40 4 72 1.8E-8 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CB4_RS13680 74c379996b08ca2ffe055518b64ef95b 74 Gene3D G3DSA:3.40.630.10 1 74 2.5E-14 T 29-03-2018 CB4_RS00815 1df8f2a0c55c22bb5a2df0570b2b57ef 121 SUPERFAMILY SSF64263 2 120 1.2E-44 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00815 1df8f2a0c55c22bb5a2df0570b2b57ef 121 Pfam PF01196 Ribosomal protein L17 16 120 1.3E-39 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00815 1df8f2a0c55c22bb5a2df0570b2b57ef 121 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 28.725 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00815 1df8f2a0c55c22bb5a2df0570b2b57ef 121 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00815 1df8f2a0c55c22bb5a2df0570b2b57ef 121 Gene3D G3DSA:3.90.1030.10 1 121 5.2E-48 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00815 1df8f2a0c55c22bb5a2df0570b2b57ef 121 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 121 5.5E-46 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05245 2b3c1b3834d8509d2cd483b114ee54df 333 SUPERFAMILY SSF56300 36 319 3.04E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS05245 2b3c1b3834d8509d2cd483b114ee54df 333 Gene3D G3DSA:3.60.21.10 23 325 2.4E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS05245 2b3c1b3834d8509d2cd483b114ee54df 333 Pfam PF00149 Calcineurin-like phosphoesterase 40 255 9.1E-20 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CB4_RS17700 b194a2a87e4561b4a2868bf1a317821e 318 SUPERFAMILY SSF103481 46 152 1.7E-10 T 29-03-2018 CB4_RS17700 b194a2a87e4561b4a2868bf1a317821e 318 Pfam PF00892 EamA-like transporter family 9 150 2.9E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS17700 b194a2a87e4561b4a2868bf1a317821e 318 Pfam PF00892 EamA-like transporter family 165 295 1.2E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS17700 b194a2a87e4561b4a2868bf1a317821e 318 SUPERFAMILY SSF103481 196 299 5.49E-7 T 29-03-2018 CB4_RS08205 d9a013c650ed36cc5cf0805ea17036f1 546 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 15 541 2.1E-159 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CB4_RS08205 d9a013c650ed36cc5cf0805ea17036f1 546 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 4 545 29.036 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CB4_RS08205 d9a013c650ed36cc5cf0805ea17036f1 546 PIRSF PIRSF012535 4 545 1.8E-151 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CB4_RS08205 d9a013c650ed36cc5cf0805ea17036f1 546 Pfam PF10079 Bacillithiol biosynthesis BshC 6 540 1.3E-159 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CB4_RS12255 0eaa31578a63678311242d854d9176a7 66 Gene3D G3DSA:2.40.50.140 1 66 1.1E-28 T 29-03-2018 CB4_RS12255 0eaa31578a63678311242d854d9176a7 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CB4_RS12255 0eaa31578a63678311242d854d9176a7 66 SUPERFAMILY SSF50249 1 64 2.82E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS12255 0eaa31578a63678311242d854d9176a7 66 PIRSF PIRSF002599 1 66 1.9E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CB4_RS12255 0eaa31578a63678311242d854d9176a7 66 SMART SM00357 3 66 1.3E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CB4_RS12255 0eaa31578a63678311242d854d9176a7 66 PRINTS PR00050 Cold shock protein signature 39 57 1.7E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS12255 0eaa31578a63678311242d854d9176a7 66 PRINTS PR00050 Cold shock protein signature 4 19 1.7E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS12255 0eaa31578a63678311242d854d9176a7 66 PRINTS PR00050 Cold shock protein signature 24 33 1.7E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS12255 0eaa31578a63678311242d854d9176a7 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.7E-32 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS05160 0eb10634feacd50e0479882dcaff1c38 292 Gene3D G3DSA:1.10.10.10 1 83 3.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS05160 0eb10634feacd50e0479882dcaff1c38 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS05160 0eb10634feacd50e0479882dcaff1c38 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS05160 0eb10634feacd50e0479882dcaff1c38 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS05160 0eb10634feacd50e0479882dcaff1c38 292 Gene3D G3DSA:3.40.190.10 176 263 1.2E-20 T 29-03-2018 CB4_RS05160 0eb10634feacd50e0479882dcaff1c38 292 Pfam PF03466 LysR substrate binding domain 88 289 2.5E-47 T 29-03-2018 IPR005119 LysR, substrate-binding CB4_RS05160 0eb10634feacd50e0479882dcaff1c38 292 Gene3D G3DSA:3.40.190.10 87 175 2.0E-21 T 29-03-2018 CB4_RS05160 0eb10634feacd50e0479882dcaff1c38 292 SUPERFAMILY SSF46785 1 86 2.87E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS05160 0eb10634feacd50e0479882dcaff1c38 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS05160 0eb10634feacd50e0479882dcaff1c38 292 SUPERFAMILY SSF53850 90 290 1.0E-43 T 29-03-2018 CB4_RS08720 696c68e7783811db0169c4df06f5c4fb 120 Pfam PF02021 Uncharacterised protein family UPF0102 14 103 1.6E-29 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CB4_RS08720 696c68e7783811db0169c4df06f5c4fb 120 SUPERFAMILY SSF52980 14 106 2.41E-21 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CB4_RS08720 696c68e7783811db0169c4df06f5c4fb 120 Hamap MF_00048 UPF0102 protein YraN [yraN]. 7 116 21.518 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CB4_RS08720 696c68e7783811db0169c4df06f5c4fb 120 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 4 105 1.6E-20 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CB4_RS08720 696c68e7783811db0169c4df06f5c4fb 120 Gene3D G3DSA:3.40.1350.10 13 120 3.9E-34 T 29-03-2018 CB4_RS14920 e949e883f71fbeb02f6519526b908efe 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CB4_RS14920 e949e883f71fbeb02f6519526b908efe 392 Gene3D G3DSA:3.40.640.10 44 272 2.3E-54 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS14920 e949e883f71fbeb02f6519526b908efe 392 Pfam PF00155 Aminotransferase class I and II 31 385 8.8E-76 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS14920 e949e883f71fbeb02f6519526b908efe 392 Gene3D G3DSA:3.90.1150.10 273 391 6.3E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS14920 e949e883f71fbeb02f6519526b908efe 392 SUPERFAMILY SSF53383 1 390 2.13E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS14920 e949e883f71fbeb02f6519526b908efe 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 1.7E-15 T 29-03-2018 CB4_RS14920 e949e883f71fbeb02f6519526b908efe 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 1.7E-15 T 29-03-2018 CB4_RS14920 e949e883f71fbeb02f6519526b908efe 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 1.7E-15 T 29-03-2018 CB4_RS14920 e949e883f71fbeb02f6519526b908efe 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 1.7E-15 T 29-03-2018 CB4_RS14920 e949e883f71fbeb02f6519526b908efe 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 1.7E-15 T 29-03-2018 CB4_RS07125 c460aa95d6fdf8d0197a0275fe9a7fcf 259 Pfam PF02565 Recombination protein O C terminal 82 238 1.9E-37 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CB4_RS07125 c460aa95d6fdf8d0197a0275fe9a7fcf 259 SUPERFAMILY SSF57863 81 230 1.05E-42 T 29-03-2018 CB4_RS07125 c460aa95d6fdf8d0197a0275fe9a7fcf 259 Gene3D G3DSA:2.40.50.140 2 81 7.8E-25 T 29-03-2018 CB4_RS07125 c460aa95d6fdf8d0197a0275fe9a7fcf 259 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 30.255 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CB4_RS07125 c460aa95d6fdf8d0197a0275fe9a7fcf 259 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 243 3.4E-75 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CB4_RS07125 c460aa95d6fdf8d0197a0275fe9a7fcf 259 SUPERFAMILY SSF50249 3 78 1.59E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS07125 c460aa95d6fdf8d0197a0275fe9a7fcf 259 Pfam PF11967 Recombination protein O N terminal 4 78 1.1E-24 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CB4_RS18290 b84aab6e54ed8964d548dd580da0c600 293 Pfam PF00005 ABC transporter 3 115 4.4E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS18290 b84aab6e54ed8964d548dd580da0c600 293 Gene3D G3DSA:3.40.50.300 1 240 3.5E-50 T 29-03-2018 CB4_RS18290 b84aab6e54ed8964d548dd580da0c600 293 SUPERFAMILY SSF52540 2 196 2.6E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS18290 b84aab6e54ed8964d548dd580da0c600 293 ProSitePatterns PS00211 ABC transporters family signature. 88 102 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS14205 325fd19613e0c23237035cc27bc6d4cb 263 Pfam PF01522 Polysaccharide deacetylase 93 225 3.9E-23 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS14205 325fd19613e0c23237035cc27bc6d4cb 263 Gene3D G3DSA:3.20.20.370 36 259 3.0E-41 T 29-03-2018 CB4_RS14205 325fd19613e0c23237035cc27bc6d4cb 263 SUPERFAMILY SSF88713 57 246 1.63E-35 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 Gene3D G3DSA:1.10.287.130 230 303 8.7E-14 T 29-03-2018 CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 SMART SM00387 352 464 3.6E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 SMART SM00304 186 239 6.3E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 SUPERFAMILY SSF47384 225 305 1.96E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 462 3.2E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 SMART SM00388 240 307 7.4E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 Gene3D G3DSA:3.30.565.10 321 474 5.1E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 3.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 3.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 461 3.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 SUPERFAMILY SSF158472 188 236 1.15E-6 T 29-03-2018 CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 SUPERFAMILY SSF55874 297 464 5.89E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00150 a58d61b79f2f7ac39a9dac6ff829a1ae 475 Pfam PF00512 His Kinase A (phospho-acceptor) domain 241 305 1.0E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 Gene3D G3DSA:3.40.50.880 1 190 4.2E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 9.5E-14 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 9.5E-14 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 9.5E-14 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.1E-5 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.1E-5 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00097 Anthranilate synthase component II signature 164 177 2.4E-36 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.4E-36 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.4E-36 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.4E-36 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.4E-36 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.4E-36 T 29-03-2018 CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 SUPERFAMILY SSF52317 1 188 1.26E-56 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 Pfam PF00117 Glutamine amidotransferase class-I 4 186 2.1E-54 T 29-03-2018 IPR017926 Glutamine amidotransferase CB4_RS01360 96ccd1fcf3824ba9127925101d1a6df4 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 1.7E-85 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 Pfam PF10145 Phage-related minor tail protein 252 450 4.1E-50 T 29-03-2018 IPR010090 Phage tail tape measure protein CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 Gene3D G3DSA:1.20.5.1230 721 871 1.5E-15 T 29-03-2018 CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 Gene3D G3DSA:1.20.5.50 9 126 8.8E-5 T 29-03-2018 CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 Gene3D G3DSA:1.20.1170.10 1034 1300 0.0014 T 29-03-2018 CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 Gene3D G3DSA:1.20.1480.30 611 694 0.0017 T 29-03-2018 CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 Gene3D G3DSA:1.20.1480.30 1539 1675 1.9E-6 T 29-03-2018 CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 Gene3D G3DSA:3.90.20.10 1304 1463 0.12 T 29-03-2018 CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 213 558 3.0E-84 T 29-03-2018 IPR010090 Phage tail tape measure protein CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 936 1408 3.0E-8 T 29-03-2018 CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 SUPERFAMILY SSF57997 25 197 1.7E-5 T 29-03-2018 CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 Gene3D G3DSA:1.10.287.700 872 961 3.8E-10 T 29-03-2018 CB4_RS08950 52471d6d4f9bd0f16d776919541ea000 1736 Gene3D G3DSA:1.20.120.330 127 517 2.2E-6 T 29-03-2018 CB4_RS16555 4bc668a44da5b508cd5a80269e51e833 322 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 132 142 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CB4_RS16555 4bc668a44da5b508cd5a80269e51e833 322 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 94 105 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CB4_RS16555 4bc668a44da5b508cd5a80269e51e833 322 Pfam PF00082 Subtilase family 89 299 1.1E-46 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CB4_RS16555 4bc668a44da5b508cd5a80269e51e833 322 Gene3D G3DSA:3.40.50.200 52 315 1.2E-81 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CB4_RS16555 4bc668a44da5b508cd5a80269e51e833 322 SUPERFAMILY SSF52743 70 299 3.67E-82 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CB4_RS16555 4bc668a44da5b508cd5a80269e51e833 322 PRINTS PR00723 Subtilisin serine protease family (S8) signature 128 141 3.2E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CB4_RS16555 4bc668a44da5b508cd5a80269e51e833 322 PRINTS PR00723 Subtilisin serine protease family (S8) signature 281 297 3.2E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CB4_RS16555 4bc668a44da5b508cd5a80269e51e833 322 PRINTS PR00723 Subtilisin serine protease family (S8) signature 89 108 3.2E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CB4_RS14940 47f33853dade38c697217e437c7355c7 432 Gene3D G3DSA:2.30.40.10 2 73 1.4E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS14940 47f33853dade38c697217e437c7355c7 432 Gene3D G3DSA:3.20.20.140 74 372 1.5E-68 T 29-03-2018 CB4_RS14940 47f33853dade38c697217e437c7355c7 432 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 430 44.976 T 29-03-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 CB4_RS14940 47f33853dade38c697217e437c7355c7 432 SUPERFAMILY SSF51556 58 356 3.57E-101 T 29-03-2018 IPR032466 Metal-dependent hydrolase CB4_RS14940 47f33853dade38c697217e437c7355c7 432 Pfam PF01979 Amidohydrolase family 55 403 6.9E-75 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CB4_RS14940 47f33853dade38c697217e437c7355c7 432 SUPERFAMILY SSF51338 1 58 3.24E-30 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS14940 47f33853dade38c697217e437c7355c7 432 SUPERFAMILY SSF51338 355 429 3.24E-30 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS01340 db77dfe9af3727a8508fc457f2f2d040 172 Gene3D G3DSA:3.30.70.560 3 169 4.0E-57 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CB4_RS01340 db77dfe9af3727a8508fc457f2f2d040 172 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 91 102 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CB4_RS01340 db77dfe9af3727a8508fc457f2f2d040 172 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 9 136 7.9E-38 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CB4_RS01340 db77dfe9af3727a8508fc457f2f2d040 172 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 8 136 1.3E-42 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CB4_RS01340 db77dfe9af3727a8508fc457f2f2d040 172 SUPERFAMILY SSF55083 5 144 2.22E-51 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CB4_RS05755 8797965c55106c495b65db3fb4f6e2f0 552 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 371 385 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CB4_RS05755 8797965c55106c495b65db3fb4f6e2f0 552 SMART SM00382 304 422 4.5E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS05755 8797965c55106c495b65db3fb4f6e2f0 552 Gene3D G3DSA:3.40.50.300 277 552 4.5E-70 T 29-03-2018 CB4_RS05755 8797965c55106c495b65db3fb4f6e2f0 552 Gene3D G3DSA:3.30.450.90 139 276 1.5E-46 T 29-03-2018 CB4_RS05755 8797965c55106c495b65db3fb4f6e2f0 552 Pfam PF00437 Type II/IV secretion system protein 178 443 4.9E-84 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CB4_RS05755 8797965c55106c495b65db3fb4f6e2f0 552 SUPERFAMILY SSF52540 167 549 6.68E-102 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05755 8797965c55106c495b65db3fb4f6e2f0 552 SUPERFAMILY SSF160246 2 140 2.09E-46 T 29-03-2018 CB4_RS05755 8797965c55106c495b65db3fb4f6e2f0 552 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 39 145 3.1E-26 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 CB4_RS16600 f38fba0a40b4ef85439390d9a1890a0e 157 Pfam PF07238 PilZ domain 5 108 4.5E-8 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CB4_RS16600 f38fba0a40b4ef85439390d9a1890a0e 157 Gene3D G3DSA:2.40.10.220 1 135 1.7E-13 T 29-03-2018 CB4_RS16600 f38fba0a40b4ef85439390d9a1890a0e 157 SUPERFAMILY SSF141371 32 107 4.51E-5 T 29-03-2018 CB4_RS09770 1fb28bd49a548626422efadc164030f4 294 Pfam PF01435 Peptidase family M48 84 294 1.2E-39 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CB4_RS09770 1fb28bd49a548626422efadc164030f4 294 Hamap MF_00188 Protease HtpX [htpX]. 2 293 23.896 T 29-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CB4_RS09770 1fb28bd49a548626422efadc164030f4 294 Gene3D G3DSA:3.30.2010.10 77 167 3.6E-20 T 29-03-2018 CB4_RS01645 7a71101dac1007f9d2080915dcd92c0b 106 Gene3D G3DSA:3.30.1310.10 1 106 2.5E-39 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CB4_RS01645 7a71101dac1007f9d2080915dcd92c0b 106 PIRSF PIRSF004555 3 106 2.1E-40 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CB4_RS01645 7a71101dac1007f9d2080915dcd92c0b 106 SUPERFAMILY SSF82607 11 105 1.24E-33 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CB4_RS01645 7a71101dac1007f9d2080915dcd92c0b 106 Pfam PF02575 YbaB/EbfC DNA-binding family 11 101 2.2E-36 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CB4_RS01645 7a71101dac1007f9d2080915dcd92c0b 106 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 105 1.3E-31 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CB4_RS01645 7a71101dac1007f9d2080915dcd92c0b 106 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 99 23.652 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CB4_RS10140 8ea8525be135b79df6774a58eec1c281 284 Gene3D G3DSA:1.10.3720.10 10 284 1.4E-33 T 29-03-2018 CB4_RS10140 8ea8525be135b79df6774a58eec1c281 284 SUPERFAMILY SSF161098 6 278 1.31E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS10140 8ea8525be135b79df6774a58eec1c281 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 281 1.0E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS17740 740492280d0bb4b05c740c1f3af07fb3 374 PRINTS PR00164 ABC-2 type transport system membrane protein signature 296 315 4.7E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CB4_RS17740 740492280d0bb4b05c740c1f3af07fb3 374 PRINTS PR00164 ABC-2 type transport system membrane protein signature 259 283 4.7E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CB4_RS17740 740492280d0bb4b05c740c1f3af07fb3 374 PRINTS PR00164 ABC-2 type transport system membrane protein signature 316 335 4.7E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CB4_RS17740 740492280d0bb4b05c740c1f3af07fb3 374 Pfam PF12698 ABC-2 family transporter protein 23 366 1.9E-46 T 29-03-2018 CB4_RS17740 740492280d0bb4b05c740c1f3af07fb3 374 Gene3D G3DSA:3.40.1710.10 37 194 1.1E-25 T 29-03-2018 CB4_RS09160 2316bad5f1f01a3d60fc3ccc9f468129 120 SUPERFAMILY SSF52172 4 119 1.42E-40 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS09160 2316bad5f1f01a3d60fc3ccc9f468129 120 Pfam PF00072 Response regulator receiver domain 5 116 2.9E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS09160 2316bad5f1f01a3d60fc3ccc9f468129 120 Gene3D G3DSA:3.40.50.2300 2 120 1.1E-40 T 29-03-2018 CB4_RS09160 2316bad5f1f01a3d60fc3ccc9f468129 120 SMART SM00448 3 115 1.1E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS07080 4684fbbd988faf9c5d2ff20844f9e950 93 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 11 91 2.2E-29 T 29-03-2018 IPR022477 Sporulation protein YqfC CB4_RS07080 4684fbbd988faf9c5d2ff20844f9e950 93 Pfam PF07873 YabP family 27 90 1.8E-17 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC CB4_RS04655 dd7983d0df970e90cf82e599e2c771ab 82 SUPERFAMILY SSF88874 1 61 1.07E-26 T 29-03-2018 CB4_RS04655 dd7983d0df970e90cf82e599e2c771ab 82 Gene3D G3DSA:3.90.1340.10 1 65 2.7E-23 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS04655 dd7983d0df970e90cf82e599e2c771ab 82 Pfam PF07484 Phage Tail Collar Domain 6 61 3.1E-26 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 176 5.9E-15 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 Gene3D G3DSA:1.20.120.440 110 199 3.7E-4 T 29-03-2018 IPR023351 YppE-like domain CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 Pfam PF00672 HAMP domain 206 256 2.4E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 334 511 5.2E-47 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 SUPERFAMILY SSF58104 294 563 4.71E-79 T 29-03-2018 CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 SUPERFAMILY SSF58104 229 261 4.71E-79 T 29-03-2018 CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 Gene3D G3DSA:1.10.287.950 327 564 1.0E-57 T 29-03-2018 CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 SMART SM00283 288 563 3.6E-83 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 Gene3D G3DSA:1.10.287.1060 234 326 1.3E-4 T 29-03-2018 CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 SMART SM00304 206 259 9.3E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 415 444 3.3E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 3 28 3.3E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS07765 fa678b49225a0890f68c11fd2967bb52 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 386 413 3.3E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS00395 77fab14a504d9e6b3b9845b4fda893dd 209 Pfam PF00881 Nitroreductase family 13 187 8.0E-31 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CB4_RS00395 77fab14a504d9e6b3b9845b4fda893dd 209 SUPERFAMILY SSF55469 6 205 1.23E-52 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS00395 77fab14a504d9e6b3b9845b4fda893dd 209 Gene3D G3DSA:3.40.109.10 1 205 1.9E-44 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS13805 1070e588450847e2b25fb13d7efe2b37 180 Gene3D G3DSA:1.10.3450.10 1 131 1.8E-37 T 29-03-2018 IPR023203 TTHA0068-like domain CB4_RS13805 1070e588450847e2b25fb13d7efe2b37 180 SUPERFAMILY SSF140663 2 117 3.4E-30 T 29-03-2018 IPR023203 TTHA0068-like domain CB4_RS13805 1070e588450847e2b25fb13d7efe2b37 180 Pfam PF03745 Domain of unknown function (DUF309) 8 65 2.2E-23 T 29-03-2018 IPR005500 Protein of unknown function DUF309 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 8.2E-33 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 8.2E-33 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 8.2E-33 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 8.2E-33 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 8.2E-33 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 Gene3D G3DSA:3.30.930.10 106 428 1.4E-99 T 29-03-2018 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 1.3E-179 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 3.5E-30 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 Gene3D G3DSA:1.10.287.40 2 105 1.4E-24 T 29-03-2018 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 8.6E-38 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 PIRSF PIRSF001529 1 426 1.1E-186 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 SUPERFAMILY SSF46589 1 113 3.82E-29 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 42.947 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CB4_RS01835 0bb2c25b39bf33873f438e93e1ce3104 428 SUPERFAMILY SSF55681 117 418 7.9E-104 T 29-03-2018 CB4_RS13515 a1028d372008bb5bdec2baa0069c0ee9 229 SMART SM00448 2 112 1.4E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13515 a1028d372008bb5bdec2baa0069c0ee9 229 SUPERFAMILY SSF46894 130 227 1.7E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS13515 a1028d372008bb5bdec2baa0069c0ee9 229 Gene3D G3DSA:3.40.50.2300 2 124 5.1E-31 T 29-03-2018 CB4_RS13515 a1028d372008bb5bdec2baa0069c0ee9 229 SUPERFAMILY SSF52172 2 126 2.13E-38 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS13515 a1028d372008bb5bdec2baa0069c0ee9 229 Pfam PF00072 Response regulator receiver domain 4 113 7.4E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13515 a1028d372008bb5bdec2baa0069c0ee9 229 SMART SM00862 151 227 3.2E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS13515 a1028d372008bb5bdec2baa0069c0ee9 229 Gene3D G3DSA:1.10.10.10 125 229 1.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13515 a1028d372008bb5bdec2baa0069c0ee9 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 2.2E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS02285 52fc9870bce23f457a8139a60239ce14 307 Gene3D G3DSA:2.60.40.420 117 281 1.3E-41 T 29-03-2018 IPR008972 Cupredoxin CB4_RS02285 52fc9870bce23f457a8139a60239ce14 307 SUPERFAMILY SSF49503 122 268 3.74E-41 T 29-03-2018 IPR008972 Cupredoxin CB4_RS02285 52fc9870bce23f457a8139a60239ce14 307 SUPERFAMILY SSF81464 18 118 1.59E-19 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02285 52fc9870bce23f457a8139a60239ce14 307 PIRSF PIRSF000292 2 307 1.8E-94 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CB4_RS02285 52fc9870bce23f457a8139a60239ce14 307 Gene3D G3DSA:1.10.287.90 30 116 4.1E-19 T 29-03-2018 CB4_RS02285 52fc9870bce23f457a8139a60239ce14 307 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 149 224 7.4E-6 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS11975 bb3802528b852f8a53dc17b8c3fffe7f 375 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 66 291 1.2E-56 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CB4_RS11975 bb3802528b852f8a53dc17b8c3fffe7f 375 SUPERFAMILY SSF56300 68 312 1.93E-40 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS11975 bb3802528b852f8a53dc17b8c3fffe7f 375 SMART SM00854 65 292 5.2E-84 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CB4_RS11975 bb3802528b852f8a53dc17b8c3fffe7f 375 Gene3D G3DSA:3.60.21.10 49 339 2.1E-46 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS03205 81528a24c38cf997b2d9d518afc12786 364 Gene3D G3DSA:3.40.640.10 1 225 1.9E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS03205 81528a24c38cf997b2d9d518afc12786 364 TIGRFAM TIGR02379 ECA_wecE: TDP-4-keto-6-deoxy-D-glucose transaminase 1 356 3.3E-190 T 29-03-2018 IPR012749 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE-like MetaCyc: PWY-7315 CB4_RS03205 81528a24c38cf997b2d9d518afc12786 364 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 3 354 7.4E-84 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CB4_RS03205 81528a24c38cf997b2d9d518afc12786 364 Gene3D G3DSA:3.90.1150.10 226 364 9.0E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS03205 81528a24c38cf997b2d9d518afc12786 364 PIRSF PIRSF000390 1 362 1.1E-102 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CB4_RS03205 81528a24c38cf997b2d9d518afc12786 364 SUPERFAMILY SSF53383 2 357 8.7E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS10880 70410b8fdc45148fa9c647d8a323b857 524 Pfam PF00704 Glycosyl hydrolases family 18 266 509 8.1E-26 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CB4_RS10880 70410b8fdc45148fa9c647d8a323b857 524 Gene3D G3DSA:3.20.20.80 117 524 3.7E-48 T 29-03-2018 CB4_RS10880 70410b8fdc45148fa9c647d8a323b857 524 Pfam PF00395 S-layer homology domain 29 70 3.2E-8 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS10880 70410b8fdc45148fa9c647d8a323b857 524 Pfam PF00395 S-layer homology domain 153 196 3.2E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS10880 70410b8fdc45148fa9c647d8a323b857 524 Pfam PF00395 S-layer homology domain 89 132 7.7E-6 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS10880 70410b8fdc45148fa9c647d8a323b857 524 SMART SM00636 217 511 1.8E-10 T 29-03-2018 IPR011583 Chitinase II GO:0008061 CB4_RS10880 70410b8fdc45148fa9c647d8a323b857 524 SUPERFAMILY SSF51445 248 426 5.04E-42 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CB4_RS10880 70410b8fdc45148fa9c647d8a323b857 524 SUPERFAMILY SSF51445 483 518 5.04E-42 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CB4_RS01920 ada321ba7f6c9d8f144712da827b5e96 120 Gene3D G3DSA:3.30.230.10 1 116 5.3E-32 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS01920 ada321ba7f6c9d8f144712da827b5e96 120 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 109 1.4E-30 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CB4_RS01920 ada321ba7f6c9d8f144712da827b5e96 120 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 110 6.0E-28 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CB4_RS01920 ada321ba7f6c9d8f144712da827b5e96 120 SUPERFAMILY SSF54211 3 111 1.44E-31 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS01920 ada321ba7f6c9d8f144712da827b5e96 120 Pfam PF00825 Ribonuclease P 2 108 8.3E-33 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CB4_RS01920 ada321ba7f6c9d8f144712da827b5e96 120 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 20.029 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CB4_RS01920 ada321ba7f6c9d8f144712da827b5e96 120 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 29-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CB4_RS10765 89667742e5ef26e8719a5e52ca4148ea 292 SUPERFAMILY SSF103481 186 290 1.96E-17 T 29-03-2018 CB4_RS10765 89667742e5ef26e8719a5e52ca4148ea 292 Pfam PF00892 EamA-like transporter family 6 140 1.8E-24 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS10765 89667742e5ef26e8719a5e52ca4148ea 292 Pfam PF00892 EamA-like transporter family 151 286 1.1E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS10765 89667742e5ef26e8719a5e52ca4148ea 292 SUPERFAMILY SSF103481 40 141 4.32E-14 T 29-03-2018 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 44.977 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 2.1E-166 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 Pfam PF08442 ATP-grasp domain 2 203 6.5E-82 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 Gene3D G3DSA:3.30.470.20 96 239 5.3E-56 T 29-03-2018 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 Gene3D G3DSA:3.40.50.261 240 385 2.1E-42 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 Pfam PF00549 CoA-ligase 262 380 7.2E-25 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 SUPERFAMILY SSF56059 1 238 8.93E-85 T 29-03-2018 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 PIRSF PIRSF001554 1 386 4.3E-154 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 Gene3D G3DSA:3.30.1490.20 21 95 1.4E-25 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS09030 41df1027da89af5af250ee61c2cb6095 386 SUPERFAMILY SSF52210 241 385 2.88E-54 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CB4_RS03385 7fb187661f18a4c04607e34f9daf88e2 173 ProSitePatterns PS01265 Tpx family signature. 88 99 - T 29-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CB4_RS03385 7fb187661f18a4c04607e34f9daf88e2 173 Gene3D G3DSA:3.40.30.10 17 169 6.1E-24 T 29-03-2018 CB4_RS03385 7fb187661f18a4c04607e34f9daf88e2 173 Hamap MF_00269 Probable thiol peroxidase [tpx]. 8 168 37.65 T 29-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CB4_RS03385 7fb187661f18a4c04607e34f9daf88e2 173 Pfam PF08534 Redoxin 24 163 2.4E-21 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CB4_RS03385 7fb187661f18a4c04607e34f9daf88e2 173 SUPERFAMILY SSF52833 9 165 2.14E-42 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 Gene3D G3DSA:3.40.50.2300 1 134 1.8E-29 T 29-03-2018 CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 348 357 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 Pfam PF00072 Response regulator receiver domain 5 112 1.2E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 Gene3D G3DSA:1.10.10.60 420 483 7.2E-9 T 29-03-2018 CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 Pfam PF02954 Bacterial regulatory protein, Fis family 452 478 5.8E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 Pfam PF00158 Sigma-54 interaction domain 139 305 2.5E-62 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 Gene3D G3DSA:1.10.8.60 311 386 1.1E-19 T 29-03-2018 CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 SUPERFAMILY SSF52172 2 182 6.4E-34 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 SUPERFAMILY SSF52540 139 371 2.89E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 Gene3D G3DSA:3.40.50.300 135 310 2.2E-24 T 29-03-2018 CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 SMART SM00382 159 302 8.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS10590 3ef43908f88f4c5a2b642c403236861d 483 SMART SM00448 2 114 2.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS18125 f40edd991bc3ff1b82c7d583ff82fc92 99 Pfam PF07110 EthD domain 16 87 9.6E-10 T 29-03-2018 IPR009799 EthD domain CB4_RS18125 f40edd991bc3ff1b82c7d583ff82fc92 99 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 98 6.2E-28 T 29-03-2018 IPR009799 EthD domain CB4_RS18125 f40edd991bc3ff1b82c7d583ff82fc92 99 Gene3D G3DSA:3.30.70.100 1 99 1.5E-21 T 29-03-2018 CB4_RS18125 f40edd991bc3ff1b82c7d583ff82fc92 99 SUPERFAMILY SSF54909 1 98 1.41E-23 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 Pfam PF01541 GIY-YIG catalytic domain 15 89 2.2E-8 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 SUPERFAMILY SSF46600 181 234 1.15E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 Gene3D G3DSA:3.40.1440.10 1 97 6.5E-25 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 SMART SM00465 14 94 7.7E-24 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 SUPERFAMILY SSF47781 500 586 6.99E-21 T 29-03-2018 IPR010994 RuvA domain 2-like CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 568 1.2E-201 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 Gene3D G3DSA:4.10.860.10 174 232 8.3E-14 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 Hamap MF_00203 UvrABC system protein C [uvrC]. 1 585 27.768 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 SUPERFAMILY SSF82771 13 96 4.84E-22 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 375 521 1.6E-54 T 29-03-2018 IPR001162 UvrC family homology region CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 Pfam PF02151 UvrB/uvrC motif 199 225 4.6E-8 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS05510 b01d5fa623526f549f62f7879cc933c6 599 Gene3D G3DSA:1.10.150.20 527 586 3.9E-13 T 29-03-2018 CB4_RS08400 60b883cf8874d03b8b0e46e4b6789456 265 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 3 265 36.202 T 29-03-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit CB4_RS08400 60b883cf8874d03b8b0e46e4b6789456 265 SUPERFAMILY SSF63380 6 99 5.02E-19 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CB4_RS08400 60b883cf8874d03b8b0e46e4b6789456 265 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 221 263 1.7E-16 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CB4_RS08400 60b883cf8874d03b8b0e46e4b6789456 265 SUPERFAMILY SSF52343 94 263 9.69E-33 T 29-03-2018 CB4_RS08400 60b883cf8874d03b8b0e46e4b6789456 265 Gene3D G3DSA:2.10.240.10 221 264 8.2E-17 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CB4_RS08400 60b883cf8874d03b8b0e46e4b6789456 265 PRINTS PR00409 Phthalate dioxygenase reductase family signature 111 130 9.7E-5 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CB4_RS08400 60b883cf8874d03b8b0e46e4b6789456 265 PRINTS PR00409 Phthalate dioxygenase reductase family signature 192 200 9.7E-5 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CB4_RS08400 60b883cf8874d03b8b0e46e4b6789456 265 Gene3D G3DSA:3.40.50.80 102 219 4.5E-14 T 29-03-2018 CB4_RS08400 60b883cf8874d03b8b0e46e4b6789456 265 Gene3D G3DSA:2.40.30.10 2 97 2.9E-13 T 29-03-2018 CB4_RS08400 60b883cf8874d03b8b0e46e4b6789456 265 PIRSF PIRSF006816 2 265 8.1E-64 T 29-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CB4_RS00510 bfdfb2f8ba0eea3d7adae524f8d1065c 200 SUPERFAMILY SSF51182 2 174 5.09E-35 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS00510 bfdfb2f8ba0eea3d7adae524f8d1065c 200 Gene3D G3DSA:2.60.120.10 104 195 1.5E-4 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS00510 bfdfb2f8ba0eea3d7adae524f8d1065c 200 Pfam PF05962 HutD 9 178 7.0E-29 T 29-03-2018 IPR010282 Uncharacterised protein family HutD/Ves CB4_RS00510 bfdfb2f8ba0eea3d7adae524f8d1065c 200 Gene3D G3DSA:2.60.120.10 4 103 3.0E-23 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS01265 962a39e6adcd56a4aa43ecea9d4ff03c 174 Pfam PF02151 UvrB/uvrC motif 135 170 1.1E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS01265 962a39e6adcd56a4aa43ecea9d4ff03c 174 PIRSF PIRSF015034 1 174 4.8E-67 T 29-03-2018 IPR025542 YacH protein CB4_RS01265 962a39e6adcd56a4aa43ecea9d4ff03c 174 SUPERFAMILY SSF46600 133 171 1.06E-6 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS01265 962a39e6adcd56a4aa43ecea9d4ff03c 174 Gene3D G3DSA:4.10.860.10 100 173 4.8E-12 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS09375 effdecc800e06db07a92344a7591aba4 149 Gene3D G3DSA:2.70.40.10 112 149 3.3E-16 T 29-03-2018 CB4_RS09375 effdecc800e06db07a92344a7591aba4 149 Pfam PF00692 dUTPase 18 148 2.1E-32 T 29-03-2018 IPR029054 dUTPase-like CB4_RS09375 effdecc800e06db07a92344a7591aba4 149 TIGRFAM TIGR00576 dut: dUTP diphosphatase 12 148 2.4E-50 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CB4_RS09375 effdecc800e06db07a92344a7591aba4 149 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 4 149 31.906 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CB4_RS09375 effdecc800e06db07a92344a7591aba4 149 Gene3D G3DSA:2.70.40.10 1 111 9.0E-41 T 29-03-2018 CB4_RS09375 effdecc800e06db07a92344a7591aba4 149 SUPERFAMILY SSF51283 5 149 2.49E-49 T 29-03-2018 IPR029054 dUTPase-like CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 Pfam PF00117 Glutamine amidotransferase class-I 10 190 4.6E-41 T 29-03-2018 IPR017926 Glutamine amidotransferase CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 Pfam PF00958 GMP synthase C terminal domain 420 511 1.2E-45 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 Gene3D G3DSA:3.40.50.880 5 191 1.1E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 SUPERFAMILY SSF52317 5 227 1.59E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 Gene3D G3DSA:3.40.50.620 198 387 3.5E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 Gene3D G3DSA:3.30.300.10 388 512 2.9E-53 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 512 2.2E-159 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 Pfam PF02540 NAD synthase 205 278 3.8E-6 T 29-03-2018 IPR022310 NAD/GMP synthase CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 PRINTS PR00097 Anthranilate synthase component II signature 52 61 3.3E-5 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 PRINTS PR00097 Anthranilate synthase component II signature 167 180 3.3E-5 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 PRINTS PR00097 Anthranilate synthase component II signature 79 90 3.3E-5 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 49 63 6.1E-5 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 6.1E-5 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 8 22 6.1E-5 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 4.1E-7 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 4.1E-7 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 4.1E-7 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 SUPERFAMILY SSF52402 187 405 2.05E-63 T 29-03-2018 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 5 512 55.862 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 8 195 2.7E-79 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CB4_RS20430 b7b0dbbdef1dac709fa20ac774160a82 512 SUPERFAMILY SSF54810 392 512 7.32E-52 T 29-03-2018 CB4_RS07470 4d9e748c9c5d08dbd596cd075e3c38d9 340 Gene3D G3DSA:3.40.190.10 139 228 4.1E-19 T 29-03-2018 CB4_RS07470 4d9e748c9c5d08dbd596cd075e3c38d9 340 Pfam PF09084 NMT1/THI5 like 54 267 1.2E-66 T 29-03-2018 IPR015168 SsuA/THI5-like CB4_RS07470 4d9e748c9c5d08dbd596cd075e3c38d9 340 Gene3D G3DSA:3.40.190.10 42 138 5.8E-19 T 29-03-2018 CB4_RS07470 4d9e748c9c5d08dbd596cd075e3c38d9 340 Gene3D G3DSA:3.40.190.10 237 337 0.014 T 29-03-2018 CB4_RS07470 4d9e748c9c5d08dbd596cd075e3c38d9 340 SUPERFAMILY SSF53850 46 333 1.61E-37 T 29-03-2018 CB4_RS04235 a0e4446dbd6b0288c560c5452acf776f 516 Gene3D G3DSA:3.40.309.10 303 491 5.1E-63 T 29-03-2018 CB4_RS04235 a0e4446dbd6b0288c560c5452acf776f 516 Pfam PF00171 Aldehyde dehydrogenase family 49 510 4.8E-149 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS04235 a0e4446dbd6b0288c560c5452acf776f 516 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 4 515 8.3E-228 T 29-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CB4_RS04235 a0e4446dbd6b0288c560c5452acf776f 516 Gene3D G3DSA:3.40.605.10 22 302 1.2E-76 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS04235 a0e4446dbd6b0288c560c5452acf776f 516 SUPERFAMILY SSF53720 3 511 4.71E-149 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS04235 a0e4446dbd6b0288c560c5452acf776f 516 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 314 325 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CB4_RS04235 a0e4446dbd6b0288c560c5452acf776f 516 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 286 293 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CB4_RS11655 519902815f695ff1779279343b2601ba 196 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 22 157 4.6E-42 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 CB4_RS11655 519902815f695ff1779279343b2601ba 196 SUPERFAMILY SSF53163 12 193 1.96E-37 T 29-03-2018 IPR023430 Peptidase HybD-like domain CB4_RS11655 519902815f695ff1779279343b2601ba 196 Pfam PF06866 Protein of unknown function (DUF1256) 11 154 1.7E-40 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 CB4_RS11655 519902815f695ff1779279343b2601ba 196 Gene3D G3DSA:3.40.50.1450 2 195 1.5E-29 T 29-03-2018 IPR023430 Peptidase HybD-like domain CB4_RS11290 0c08a4899b250b6db1c73a0e4f6e9f0b 256 SUPERFAMILY SSF48613 102 251 6.92E-13 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CB4_RS11290 0c08a4899b250b6db1c73a0e4f6e9f0b 256 Pfam PF11251 Protein of unknown function (DUF3050) 17 247 2.2E-92 T 29-03-2018 IPR024423 Protein of unknown function DUF3050 CB4_RS11290 0c08a4899b250b6db1c73a0e4f6e9f0b 256 Gene3D G3DSA:1.20.910.10 3 255 4.5E-43 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CB4_RS12795 d8cbe02a672f97250754a1fb700ef426 108 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 3.5E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12795 d8cbe02a672f97250754a1fb700ef426 108 SUPERFAMILY SSF46785 3 93 2.49E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12795 d8cbe02a672f97250754a1fb700ef426 108 SMART SM00418 12 90 1.4E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12795 d8cbe02a672f97250754a1fb700ef426 108 Gene3D G3DSA:1.10.10.10 1 92 1.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12795 d8cbe02a672f97250754a1fb700ef426 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 1.3E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12795 d8cbe02a672f97250754a1fb700ef426 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 1.3E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12795 d8cbe02a672f97250754a1fb700ef426 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 1.3E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS07360 1e3e087713be0e9742e145da99e3d879 163 PRINTS PR00070 Dihydrofolate reductase signature 90 104 8.6E-12 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS07360 1e3e087713be0e9742e145da99e3d879 163 PRINTS PR00070 Dihydrofolate reductase signature 13 23 8.6E-12 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS07360 1e3e087713be0e9742e145da99e3d879 163 PRINTS PR00070 Dihydrofolate reductase signature 27 35 8.6E-12 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS07360 1e3e087713be0e9742e145da99e3d879 163 PRINTS PR00070 Dihydrofolate reductase signature 40 51 8.6E-12 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS07360 1e3e087713be0e9742e145da99e3d879 163 PIRSF PIRSF000194 1 161 1.8E-59 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS07360 1e3e087713be0e9742e145da99e3d879 163 SUPERFAMILY SSF53597 2 159 2.75E-58 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CB4_RS07360 1e3e087713be0e9742e145da99e3d879 163 Gene3D G3DSA:3.40.430.10 1 161 1.2E-52 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CB4_RS07360 1e3e087713be0e9742e145da99e3d879 163 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CB4_RS07360 1e3e087713be0e9742e145da99e3d879 163 Pfam PF00186 Dihydrofolate reductase 2 158 3.2E-60 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CB4_RS07365 9f536ba6a2c51a5320c9f701c2152988 172 SUPERFAMILY SSF47240 1 161 9.06E-59 T 29-03-2018 IPR009078 Ferritin-like superfamily CB4_RS07365 9f536ba6a2c51a5320c9f701c2152988 172 Pfam PF00210 Ferritin-like domain 8 144 3.4E-40 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CB4_RS07365 9f536ba6a2c51a5320c9f701c2152988 172 Gene3D G3DSA:1.20.1260.10 1 162 3.9E-44 T 29-03-2018 IPR012347 Ferritin-related CB4_RS20670 07daf7b8d014168083ef2ac8b923755a 224 Gene3D G3DSA:1.20.910.10 1 224 2.0E-65 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CB4_RS20670 07daf7b8d014168083ef2ac8b923755a 224 Pfam PF03070 TENA/THI-4/PQQC family 14 218 1.5E-52 T 29-03-2018 IPR004305 Thiaminase-2/PQQC CB4_RS20670 07daf7b8d014168083ef2ac8b923755a 224 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 14 218 3.0E-63 T 29-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 CB4_RS20670 07daf7b8d014168083ef2ac8b923755a 224 SUPERFAMILY SSF48613 3 217 2.37E-70 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 Gene3D G3DSA:1.10.287.130 61 133 1.3E-20 T 29-03-2018 CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 Pfam PF00512 His Kinase A (phospho-acceptor) domain 70 139 4.2E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 Gene3D G3DSA:3.30.565.10 134 297 4.9E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 SUPERFAMILY SSF47384 56 140 6.47E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 186 296 2.4E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 294 8.4E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 240 250 8.4E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 257 275 8.4E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 222 236 8.4E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 SMART SM00387 185 297 4.0E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 SUPERFAMILY SSF55874 128 295 1.44E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS16655 3e5442ae82f98af827af6921bc760d14 298 SMART SM00388 70 139 4.3E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS16800 a4de7f361862a9aea88ca832dbba083f 402 Gene3D G3DSA:1.20.1250.20 7 204 2.0E-36 T 29-03-2018 CB4_RS16800 a4de7f361862a9aea88ca832dbba083f 402 Pfam PF07690 Major Facilitator Superfamily 23 301 7.1E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS16800 a4de7f361862a9aea88ca832dbba083f 402 SUPERFAMILY SSF103473 7 397 8.37E-81 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS16800 a4de7f361862a9aea88ca832dbba083f 402 Gene3D G3DSA:1.20.1250.20 206 398 1.9E-29 T 29-03-2018 CB4_RS16800 a4de7f361862a9aea88ca832dbba083f 402 ProSitePatterns PS00217 Sugar transport proteins signature 2. 113 138 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CB4_RS16800 a4de7f361862a9aea88ca832dbba083f 402 ProSitePatterns PS00216 Sugar transport proteins signature 1. 71 87 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CB4_RS04210 58dac714ba8cd4cb0762000c5d81d200 224 Gene3D G3DSA:3.40.50.10420 40 224 1.1E-39 T 29-03-2018 CB4_RS04210 58dac714ba8cd4cb0762000c5d81d200 224 Pfam PF02589 LUD domain 47 224 4.1E-24 T 29-03-2018 IPR003741 LUD domain CB4_RS04210 58dac714ba8cd4cb0762000c5d81d200 224 SUPERFAMILY SSF100950 43 224 2.59E-34 T 29-03-2018 CB4_RS15350 b64dca6dce8c8b878098d447e625123e 380 Gene3D G3DSA:1.10.10.10 34 132 4.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15350 b64dca6dce8c8b878098d447e625123e 380 Gene3D G3DSA:1.10.10.10 254 322 7.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15350 b64dca6dce8c8b878098d447e625123e 380 Pfam PF14493 Helix-turn-helix domain 284 371 7.5E-20 T 29-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CB4_RS15350 b64dca6dce8c8b878098d447e625123e 380 Gene3D G3DSA:1.10.10.10 207 253 0.057 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 Pfam PF13184 NusA-like KH domain 229 296 3.4E-27 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 384 30.196 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 SMART SM00316 133 199 8.3E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 SUPERFAMILY SSF54814 199 277 1.83E-31 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 Gene3D G3DSA:3.30.300.20 277 347 4.4E-16 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 Pfam PF00575 S1 RNA binding domain 133 193 7.2E-7 T 29-03-2018 IPR003029 S1 domain GO:0003676 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 Gene3D G3DSA:2.40.50.140 136 197 4.6E-14 T 29-03-2018 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 Gene3D G3DSA:3.30.300.20 198 275 3.5E-35 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 Pfam PF08529 NusA N-terminal domain 4 123 1.4E-44 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 SUPERFAMILY SSF50249 132 198 4.4E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 SUPERFAMILY SSF69705 1 126 1.44E-41 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 SUPERFAMILY SSF54814 280 340 9.81E-16 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 SMART SM00322 300 378 8.9E-4 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 SMART SM00322 229 292 0.8 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 341 2.5E-127 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CB4_RS09315 2857425fefffc1aecafa6a3f6e1bc567 385 Gene3D G3DSA:3.30.1480.10 1 129 6.6E-49 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CB4_RS14780 c32685d9cb9d0d2ec770cade0e42c826 227 Pfam PF02631 RecX family 99 218 6.0E-28 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CB4_RS14780 c32685d9cb9d0d2ec770cade0e42c826 227 Gene3D G3DSA:1.10.10.10 123 168 1.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14780 c32685d9cb9d0d2ec770cade0e42c826 227 Hamap MF_01114 Regulatory protein RecX [recX]. 57 224 15.326 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CB4_RS14780 c32685d9cb9d0d2ec770cade0e42c826 227 Gene3D G3DSA:1.10.10.10 58 122 1.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14780 c32685d9cb9d0d2ec770cade0e42c826 227 Gene3D G3DSA:1.10.10.10 173 221 6.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16015 158e4eb0fdc1950999cc14d147ae0e49 247 Hamap MF_01805 Segregation and condensation protein A [scpA]. 3 247 23.953 T 29-03-2018 IPR003768 Segregation and condensation protein A CB4_RS16015 158e4eb0fdc1950999cc14d147ae0e49 247 Gene3D G3DSA:1.10.10.580 179 247 8.8E-11 T 29-03-2018 CB4_RS16015 158e4eb0fdc1950999cc14d147ae0e49 247 Pfam PF02616 Segregation and condensation protein ScpA 20 246 1.5E-46 T 29-03-2018 IPR003768 Segregation and condensation protein A CB4_RS00095 37e0b691304a8a82803e4753fb29f79a 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 12 362 1.3E-64 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS00095 37e0b691304a8a82803e4753fb29f79a 366 Pfam PF03845 Spore germination protein 19 323 3.7E-27 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS11230 13b1367f2935973be1c34f013199c16b 383 SUPERFAMILY SSF53756 4 380 6.0E-79 T 29-03-2018 CB4_RS11230 13b1367f2935973be1c34f013199c16b 383 Pfam PF13477 Glycosyl transferase 4-like 17 140 2.2E-20 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CB4_RS11230 13b1367f2935973be1c34f013199c16b 383 Gene3D G3DSA:3.40.50.2000 189 365 2.4E-43 T 29-03-2018 CB4_RS11230 13b1367f2935973be1c34f013199c16b 383 Gene3D G3DSA:3.40.50.2000 2 188 2.6E-22 T 29-03-2018 CB4_RS11230 13b1367f2935973be1c34f013199c16b 383 Pfam PF00534 Glycosyl transferases group 1 189 358 1.4E-37 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CB4_RS14750 6deb1c7d65ffb86f12c5263363d2cebe 177 Gene3D G3DSA:3.40.50.150 1 177 1.8E-24 T 29-03-2018 CB4_RS14750 6deb1c7d65ffb86f12c5263363d2cebe 177 SUPERFAMILY SSF53335 8 148 3.01E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS14750 6deb1c7d65ffb86f12c5263363d2cebe 177 Pfam PF06962 Putative rRNA methylase 40 175 2.8E-47 T 29-03-2018 IPR010719 Putative rRNA methylase CB4_RS09275 12f96e971f6b989548bfe6cb2b71308f 185 Pfam PF01765 Ribosome recycling factor 20 183 9.1E-64 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CB4_RS09275 12f96e971f6b989548bfe6cb2b71308f 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 7.7E-72 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CB4_RS09275 12f96e971f6b989548bfe6cb2b71308f 185 SUPERFAMILY SSF55194 4 184 4.32E-71 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CB4_RS09275 12f96e971f6b989548bfe6cb2b71308f 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.098 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CB4_RS09275 12f96e971f6b989548bfe6cb2b71308f 185 Gene3D G3DSA:1.10.132.20 74 184 1.3E-37 T 29-03-2018 CB4_RS09275 12f96e971f6b989548bfe6cb2b71308f 185 Gene3D G3DSA:1.10.132.20 3 73 1.8E-11 T 29-03-2018 CB4_RS09920 8667dda08764e02ee158a4fefa1d10de 451 Pfam PF00120 Glutamine synthetase, catalytic domain 127 447 7.8E-90 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS09920 8667dda08764e02ee158a4fefa1d10de 451 SMART SM01230 125 375 3.4E-80 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS09920 8667dda08764e02ee158a4fefa1d10de 451 SUPERFAMILY SSF55931 126 447 3.53E-90 T 29-03-2018 CB4_RS09920 8667dda08764e02ee158a4fefa1d10de 451 Gene3D G3DSA:3.30.590.10 126 451 3.2E-89 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CB4_RS09920 8667dda08764e02ee158a4fefa1d10de 451 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 253 268 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CB4_RS09920 8667dda08764e02ee158a4fefa1d10de 451 SUPERFAMILY SSF54368 20 123 2.49E-16 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS09920 8667dda08764e02ee158a4fefa1d10de 451 Gene3D G3DSA:3.10.20.70 14 125 1.5E-23 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 PIRSF PIRSF017184 1 509 1.0E-137 T 29-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 Gene3D G3DSA:3.40.50.10260 1 219 1.9E-70 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 445 455 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 Gene3D G3DSA:3.40.1190.20 220 508 1.4E-48 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 SUPERFAMILY SSF53613 228 504 1.82E-70 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 Pfam PF01256 Carbohydrate kinase 250 495 8.0E-55 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 Pfam PF03853 YjeF-related protein N-terminus 26 190 2.6E-45 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 226 509 23.995 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 211 26.62 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 SUPERFAMILY SSF64153 1 248 7.98E-69 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 3 212 1.2E-51 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CB4_RS20645 c298db092195de8d24e6f96fb1641eac 521 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 226 504 2.4E-65 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CB4_RS04965 53fcf1ba3522de5f9cc3b4a5f246008a 293 SUPERFAMILY SSF102114 15 280 1.83E-64 T 29-03-2018 CB4_RS04965 53fcf1ba3522de5f9cc3b4a5f246008a 293 Gene3D G3DSA:3.80.30.20 48 269 8.3E-25 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CB4_RS04965 53fcf1ba3522de5f9cc3b4a5f246008a 293 PIRSF PIRSF005963 1 293 3.9E-136 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CB4_RS04965 53fcf1ba3522de5f9cc3b4a5f246008a 293 Hamap MF_00206 Lipoyl synthase [lipA]. 1 289 145.188 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CB4_RS04965 53fcf1ba3522de5f9cc3b4a5f246008a 293 TIGRFAM TIGR00510 lipA: lipoyl synthase 3 285 5.9E-118 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CB4_RS04965 53fcf1ba3522de5f9cc3b4a5f246008a 293 SMART SM00729 51 256 8.8E-17 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS04965 53fcf1ba3522de5f9cc3b4a5f246008a 293 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 4 40 4.3E-12 T 29-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CB4_RS04965 53fcf1ba3522de5f9cc3b4a5f246008a 293 Pfam PF04055 Radical SAM superfamily 58 217 4.5E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS03455 1413f05322788975b1d3cdb06def1de8 833 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 15 110 8.4E-26 T 29-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 CB4_RS03455 1413f05322788975b1d3cdb06def1de8 833 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 470 819 4.5E-39 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CB4_RS00195 8bfe653cd7796b6a4acf820f0dd8c499 267 Gene3D G3DSA:3.40.50.300 20 258 4.9E-32 T 29-03-2018 CB4_RS00195 8bfe653cd7796b6a4acf820f0dd8c499 267 Pfam PF02421 Ferrous iron transport protein B 29 181 1.1E-58 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CB4_RS00195 8bfe653cd7796b6a4acf820f0dd8c499 267 SUPERFAMILY SSF52540 29 206 8.89E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12105 84d9c5690c6ad0846df6529541ee5b4f 492 Gene3D G3DSA:3.40.605.10 5 276 9.0E-100 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS12105 84d9c5690c6ad0846df6529541ee5b4f 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CB4_RS12105 84d9c5690c6ad0846df6529541ee5b4f 492 Gene3D G3DSA:3.40.309.10 277 472 2.4E-77 T 29-03-2018 CB4_RS12105 84d9c5690c6ad0846df6529541ee5b4f 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 285 296 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CB4_RS12105 84d9c5690c6ad0846df6529541ee5b4f 492 Pfam PF00171 Aldehyde dehydrogenase family 19 486 3.4E-178 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS12105 84d9c5690c6ad0846df6529541ee5b4f 492 SUPERFAMILY SSF53720 7 489 4.06E-175 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS13330 d63a6da583356c547c51f34ba85504fd 77 Gene3D G3DSA:1.20.1250.20 1 77 1.2E-4 T 29-03-2018 CB4_RS20285 56db88711fd81e6bc2cdee11c051f0cd 98 Pfam PF01371 Trp repressor protein 10 94 4.9E-33 T 29-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 CB4_RS20285 56db88711fd81e6bc2cdee11c051f0cd 98 Gene3D G3DSA:1.10.1270.10 1 98 1.0E-29 T 29-03-2018 CB4_RS20285 56db88711fd81e6bc2cdee11c051f0cd 98 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 2.8E-44 T 29-03-2018 IPR013368 TrpR homologue YerC/YecD CB4_RS20285 56db88711fd81e6bc2cdee11c051f0cd 98 PIRSF PIRSF012508 1 98 1.7E-44 T 29-03-2018 IPR013368 TrpR homologue YerC/YecD CB4_RS20285 56db88711fd81e6bc2cdee11c051f0cd 98 SUPERFAMILY SSF48295 4 95 2.93E-32 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CB4_RS16660 d01c71c053f5f029e38e5d8c401e976c 160 SUPERFAMILY SSF52172 27 149 4.27E-38 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS16660 d01c71c053f5f029e38e5d8c401e976c 160 SMART SM00448 26 140 2.2E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16660 d01c71c053f5f029e38e5d8c401e976c 160 Gene3D G3DSA:3.40.50.2300 21 156 7.0E-42 T 29-03-2018 CB4_RS16660 d01c71c053f5f029e38e5d8c401e976c 160 Pfam PF00072 Response regulator receiver domain 28 140 5.2E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS05045 902bb13ba439f6406b6e8de2b6ce818a 796 Gene3D G3DSA:2.60.40.10 456 552 2.8E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS05045 902bb13ba439f6406b6e8de2b6ce818a 796 Gene3D G3DSA:2.60.40.10 360 455 2.4E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS05045 902bb13ba439f6406b6e8de2b6ce818a 796 Gene3D G3DSA:2.60.40.1080 711 795 8.6E-5 T 29-03-2018 CB4_RS05045 902bb13ba439f6406b6e8de2b6ce818a 796 Pfam PF00395 S-layer homology domain 156 199 2.6E-10 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS05045 902bb13ba439f6406b6e8de2b6ce818a 796 Pfam PF00395 S-layer homology domain 33 75 5.1E-12 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS05045 902bb13ba439f6406b6e8de2b6ce818a 796 Pfam PF00395 S-layer homology domain 94 137 3.9E-10 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS05045 902bb13ba439f6406b6e8de2b6ce818a 796 SMART SM00635 369 450 0.0016 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS05045 902bb13ba439f6406b6e8de2b6ce818a 796 SMART SM00635 463 544 0.028 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS05045 902bb13ba439f6406b6e8de2b6ce818a 796 SUPERFAMILY SSF49313 462 552 4.87E-5 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CB4_RS12280 e92853551d18dfb4d0139145bbc8cb36 252 SUPERFAMILY SSF53955 60 248 1.86E-66 T 29-03-2018 IPR023346 Lysozyme-like domain CB4_RS12280 e92853551d18dfb4d0139145bbc8cb36 252 Pfam PF00912 Transglycosylase 60 226 2.0E-56 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CB4_RS12280 e92853551d18dfb4d0139145bbc8cb36 252 Gene3D G3DSA:1.10.3810.10 46 245 3.8E-66 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CB4_RS07570 705cae5e499cb51c3db70956a99879e1 262 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 35 261 1.2E-88 T 29-03-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 CB4_RS07570 705cae5e499cb51c3db70956a99879e1 262 Pfam PF01471 Putative peptidoglycan binding domain 44 97 1.3E-13 T 29-03-2018 IPR002477 Peptidoglycan binding-like CB4_RS07570 705cae5e499cb51c3db70956a99879e1 262 Gene3D G3DSA:1.10.101.10 30 109 7.1E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like CB4_RS07570 705cae5e499cb51c3db70956a99879e1 262 SUPERFAMILY SSF47090 37 102 1.88E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like CB4_RS07570 705cae5e499cb51c3db70956a99879e1 262 Pfam PF07486 Cell Wall Hydrolase 163 261 4.6E-29 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CB4_RS16375 99ea01f629be0e140c1513f182aa5eb7 327 SUPERFAMILY SSF52922 188 324 1.96E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS16375 99ea01f629be0e140c1513f182aa5eb7 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 1.5E-53 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CB4_RS16375 99ea01f629be0e140c1513f182aa5eb7 327 SUPERFAMILY SSF52518 2 204 4.81E-75 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS16375 99ea01f629be0e140c1513f182aa5eb7 327 Gene3D G3DSA:3.40.50.920 195 326 8.7E-37 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS16375 99ea01f629be0e140c1513f182aa5eb7 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 4.0E-42 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CB4_RS16375 99ea01f629be0e140c1513f182aa5eb7 327 SMART SM00861 4 179 4.5E-75 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CB4_RS16375 99ea01f629be0e140c1513f182aa5eb7 327 Gene3D G3DSA:3.40.50.970 2 194 7.5E-75 T 29-03-2018 CB4_RS14580 207a54ff05c97272ba0ddcd280bd55eb 181 SMART SM00347 55 156 8.4E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS14580 207a54ff05c97272ba0ddcd280bd55eb 181 ProSitePatterns PS01117 MarR-type HTH domain signature. 95 129 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CB4_RS14580 207a54ff05c97272ba0ddcd280bd55eb 181 SUPERFAMILY SSF46785 29 169 2.73E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14580 207a54ff05c97272ba0ddcd280bd55eb 181 Pfam PF12802 MarR family 61 120 3.2E-13 T 29-03-2018 CB4_RS14580 207a54ff05c97272ba0ddcd280bd55eb 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 146 166 2.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS14580 207a54ff05c97272ba0ddcd280bd55eb 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 2.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS14580 207a54ff05c97272ba0ddcd280bd55eb 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 112 2.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS14580 207a54ff05c97272ba0ddcd280bd55eb 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 132 2.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS14580 207a54ff05c97272ba0ddcd280bd55eb 181 Gene3D G3DSA:1.10.10.10 2 177 4.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13530 3e29a6c37b3ddd7a5eebd34870fe408d 245 Pfam PF00005 ABC transporter 21 161 2.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS13530 3e29a6c37b3ddd7a5eebd34870fe408d 245 SMART SM00382 29 209 1.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13530 3e29a6c37b3ddd7a5eebd34870fe408d 245 SUPERFAMILY SSF52540 3 232 1.13E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13530 3e29a6c37b3ddd7a5eebd34870fe408d 245 Gene3D G3DSA:3.40.50.300 1 245 1.3E-56 T 29-03-2018 CB4_RS13530 3e29a6c37b3ddd7a5eebd34870fe408d 245 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS06795 45e300ea62138403981401a6ab7b8491 882 SUPERFAMILY SSF53067 301 418 4.62E-9 T 29-03-2018 CB4_RS06795 45e300ea62138403981401a6ab7b8491 882 SUPERFAMILY SSF53067 227 273 4.62E-9 T 29-03-2018 CB4_RS06795 45e300ea62138403981401a6ab7b8491 882 Gene3D G3DSA:1.10.720.10 22 66 1.8E-4 T 29-03-2018 CB4_RS06795 45e300ea62138403981401a6ab7b8491 882 SUPERFAMILY SSF53067 568 694 3.48E-11 T 29-03-2018 CB4_RS06795 45e300ea62138403981401a6ab7b8491 882 SUPERFAMILY SSF53067 432 496 3.48E-11 T 29-03-2018 CB4_RS06795 45e300ea62138403981401a6ab7b8491 882 Gene3D G3DSA:3.30.420.40 224 444 5.8E-25 T 29-03-2018 CB4_RS06795 45e300ea62138403981401a6ab7b8491 882 Gene3D G3DSA:3.30.420.40 445 699 5.4E-20 T 29-03-2018 CB4_RS17585 5a14b710a8ba80c82a4d4506a3b3d9de 359 Gene3D G3DSA:1.10.3470.10 17 312 8.8E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS17585 5a14b710a8ba80c82a4d4506a3b3d9de 359 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 307 1.4E-41 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS00485 337dfb66e47d710c1266d39e3bedb852 437 ProSitePatterns PS00217 Sugar transport proteins signature 2. 109 134 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CB4_RS00485 337dfb66e47d710c1266d39e3bedb852 437 SUPERFAMILY SSF103473 3 426 4.97E-80 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS00485 337dfb66e47d710c1266d39e3bedb852 437 Gene3D G3DSA:1.20.1250.20 226 435 4.3E-31 T 29-03-2018 CB4_RS00485 337dfb66e47d710c1266d39e3bedb852 437 Gene3D G3DSA:1.20.1250.20 3 206 1.9E-36 T 29-03-2018 CB4_RS00485 337dfb66e47d710c1266d39e3bedb852 437 PRINTS PR00171 Sugar transporter signature 354 366 9.1E-5 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CB4_RS00485 337dfb66e47d710c1266d39e3bedb852 437 PRINTS PR00171 Sugar transporter signature 104 123 9.1E-5 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CB4_RS00485 337dfb66e47d710c1266d39e3bedb852 437 PRINTS PR00171 Sugar transporter signature 21 31 9.1E-5 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CB4_RS00485 337dfb66e47d710c1266d39e3bedb852 437 Pfam PF00083 Sugar (and other) transporter 17 428 8.9E-61 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CB4_RS16525 660be5a5881ea7a8de4c22fb585d6eee 164 ProSitePatterns PS00760 Signal peptidases I lysine active site. 75 87 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CB4_RS16525 660be5a5881ea7a8de4c22fb585d6eee 164 Pfam PF00717 Peptidase S24-like 30 93 3.9E-17 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CB4_RS16525 660be5a5881ea7a8de4c22fb585d6eee 164 ProSitePatterns PS00761 Signal peptidases I signature 3. 122 135 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CB4_RS16525 660be5a5881ea7a8de4c22fb585d6eee 164 SUPERFAMILY SSF51306 21 159 4.41E-49 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CB4_RS16525 660be5a5881ea7a8de4c22fb585d6eee 164 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 23 39 7.7E-23 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS16525 660be5a5881ea7a8de4c22fb585d6eee 164 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 73 85 7.7E-23 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS16525 660be5a5881ea7a8de4c22fb585d6eee 164 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 117 136 7.7E-23 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS16525 660be5a5881ea7a8de4c22fb585d6eee 164 Gene3D G3DSA:2.10.109.10 20 164 6.1E-44 T 29-03-2018 CB4_RS16525 660be5a5881ea7a8de4c22fb585d6eee 164 ProSitePatterns PS00501 Signal peptidases I serine active site. 32 39 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CB4_RS16525 660be5a5881ea7a8de4c22fb585d6eee 164 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 8 157 1.7E-48 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS20280 549cfe1d2ba04d25448ebb775a36c8c2 227 SUPERFAMILY SSF51395 3 219 6.77E-53 T 29-03-2018 CB4_RS20280 549cfe1d2ba04d25448ebb775a36c8c2 227 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 6 220 1.5E-72 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CB4_RS20280 549cfe1d2ba04d25448ebb775a36c8c2 227 Pfam PF01884 PcrB family 3 223 3.6E-79 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CB4_RS20280 549cfe1d2ba04d25448ebb775a36c8c2 227 Gene3D G3DSA:3.20.20.390 1 221 5.1E-30 T 29-03-2018 CB4_RS20280 549cfe1d2ba04d25448ebb775a36c8c2 227 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 1 223 27.957 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CB4_RS02575 6ee616f9522231453ef6af4c6afb1a16 213 Gene3D G3DSA:3.90.640.20 122 206 2.8E-16 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CB4_RS02575 6ee616f9522231453ef6af4c6afb1a16 213 Gene3D G3DSA:3.30.565.40 9 120 2.9E-9 T 29-03-2018 CB4_RS02575 6ee616f9522231453ef6af4c6afb1a16 213 Pfam PF13739 Domain of unknown function (DUF4163) 30 105 8.0E-8 T 29-03-2018 IPR025303 Deacetylase PdaC CB4_RS02575 6ee616f9522231453ef6af4c6afb1a16 213 Pfam PF11738 Protein of unknown function (DUF3298) 125 195 2.0E-15 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CB4_RS08155 d81c7ffc43c9948e90f6cbf88d7a12c3 234 Gene3D G3DSA:3.30.1380.20 75 234 3.3E-18 T 29-03-2018 CB4_RS08155 d81c7ffc43c9948e90f6cbf88d7a12c3 234 Pfam PF12840 Helix-turn-helix domain 8 63 1.7E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08155 d81c7ffc43c9948e90f6cbf88d7a12c3 234 SUPERFAMILY SSF46785 1 205 5.17E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08155 d81c7ffc43c9948e90f6cbf88d7a12c3 234 Gene3D G3DSA:1.10.10.10 1 74 5.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12310 b1ef0d74fa12ca46c43741c498ab194d 203 Pfam PF05728 Uncharacterised protein family (UPF0227) 6 186 1.3E-29 T 29-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA CB4_RS12310 b1ef0d74fa12ca46c43741c498ab194d 203 SUPERFAMILY SSF53474 6 156 5.0E-10 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS12310 b1ef0d74fa12ca46c43741c498ab194d 203 Gene3D G3DSA:3.40.50.1820 4 193 1.8E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS02795 7f54567341a85bb338930ba42f407a57 533 Pfam PF06418 CTP synthase N-terminus 3 267 5.4E-132 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CB4_RS02795 7f54567341a85bb338930ba42f407a57 533 Gene3D G3DSA:3.40.50.300 1 286 1.4E-135 T 29-03-2018 CB4_RS02795 7f54567341a85bb338930ba42f407a57 533 SUPERFAMILY SSF52540 1 270 5.31E-128 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02795 7f54567341a85bb338930ba42f407a57 533 SUPERFAMILY SSF52317 291 532 2.06E-85 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS02795 7f54567341a85bb338930ba42f407a57 533 Gene3D G3DSA:3.40.50.880 287 533 4.5E-74 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS02795 7f54567341a85bb338930ba42f407a57 533 Hamap MF_01227 CTP synthase [pyrG]. 2 532 53.35 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CB4_RS02795 7f54567341a85bb338930ba42f407a57 533 Pfam PF00117 Glutamine amidotransferase class-I 302 525 8.7E-58 T 29-03-2018 IPR017926 Glutamine amidotransferase CB4_RS02795 7f54567341a85bb338930ba42f407a57 533 TIGRFAM TIGR00337 PyrG: CTP synthase 2 527 7.0E-265 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CB4_RS03685 e55bbabc0852d9e8d049c3254f6097d6 207 Gene3D G3DSA:3.40.50.880 1 207 2.8E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS03685 e55bbabc0852d9e8d049c3254f6097d6 207 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 199 1.1E-71 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CB4_RS03685 e55bbabc0852d9e8d049c3254f6097d6 207 Pfam PF00117 Glutamine amidotransferase class-I 4 197 1.2E-22 T 29-03-2018 IPR017926 Glutamine amidotransferase CB4_RS03685 e55bbabc0852d9e8d049c3254f6097d6 207 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 200 37.505 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CB4_RS03685 e55bbabc0852d9e8d049c3254f6097d6 207 SUPERFAMILY SSF52317 2 201 7.37E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS03685 e55bbabc0852d9e8d049c3254f6097d6 207 PIRSF PIRSF000495 1 203 1.1E-73 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CB4_RS02910 17555fa336d419672cbeac5db9c87ef0 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 412 53.828 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CB4_RS02910 17555fa336d419672cbeac5db9c87ef0 416 SUPERFAMILY SSF53383 3 412 1.21E-183 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS02910 17555fa336d419672cbeac5db9c87ef0 416 Gene3D G3DSA:3.40.640.10 34 270 3.0E-57 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS02910 17555fa336d419672cbeac5db9c87ef0 416 Pfam PF00464 Serine hydroxymethyltransferase 5 381 1.2E-179 T 29-03-2018 CB4_RS02910 17555fa336d419672cbeac5db9c87ef0 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 219 235 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CB4_RS02910 17555fa336d419672cbeac5db9c87ef0 416 PIRSF PIRSF000412 1 413 3.0E-175 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CB4_RS02910 17555fa336d419672cbeac5db9c87ef0 416 Gene3D G3DSA:3.90.1150.10 271 411 2.3E-61 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS19790 b17df0e8eb22ff4703fc7f8da847269d 925 Gene3D G3DSA:3.40.50.300 732 901 2.4E-35 T 29-03-2018 CB4_RS19790 b17df0e8eb22ff4703fc7f8da847269d 925 SMART SM00490 774 863 1.2E-18 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS19790 b17df0e8eb22ff4703fc7f8da847269d 925 SUPERFAMILY SSF52540 427 659 9.95E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19790 b17df0e8eb22ff4703fc7f8da847269d 925 Gene3D G3DSA:3.40.50.10810 414 666 8.7E-53 T 29-03-2018 CB4_RS19790 b17df0e8eb22ff4703fc7f8da847269d 925 SMART SM00487 441 631 1.1E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS19790 b17df0e8eb22ff4703fc7f8da847269d 925 Pfam PF12419 SNF2 Helicase protein 266 396 4.6E-36 T 29-03-2018 IPR022138 Helicase SWF/SNF-related CB4_RS19790 b17df0e8eb22ff4703fc7f8da847269d 925 Pfam PF00271 Helicase conserved C-terminal domain 747 863 1.1E-15 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS19790 b17df0e8eb22ff4703fc7f8da847269d 925 SUPERFAMILY SSF52540 666 918 1.29E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19790 b17df0e8eb22ff4703fc7f8da847269d 925 Pfam PF00176 SNF2 family N-terminal domain 463 729 2.8E-59 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CB4_RS18115 b3eedc7823f19dc78e121dad860d8307 257 Gene3D G3DSA:3.90.226.10 1 217 2.0E-74 T 29-03-2018 CB4_RS18115 b3eedc7823f19dc78e121dad860d8307 257 Gene3D G3DSA:1.10.12.10 218 255 1.4E-19 T 29-03-2018 IPR014748 Crontonase, C-terminal CB4_RS18115 b3eedc7823f19dc78e121dad860d8307 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CB4_RS18115 b3eedc7823f19dc78e121dad860d8307 257 SUPERFAMILY SSF52096 2 256 5.43E-89 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS18115 b3eedc7823f19dc78e121dad860d8307 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 257 8.6E-78 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CB4_RS17265 16ecbec03925656528fa1b6e03eef4e6 354 Gene3D G3DSA:3.40.50.2300 7 129 1.3E-7 T 29-03-2018 CB4_RS17265 16ecbec03925656528fa1b6e03eef4e6 354 Pfam PF13487 HD domain 222 282 9.1E-15 T 29-03-2018 CB4_RS17265 16ecbec03925656528fa1b6e03eef4e6 354 SUPERFAMILY SSF109604 162 334 4.4E-36 T 29-03-2018 CB4_RS17265 16ecbec03925656528fa1b6e03eef4e6 354 Gene3D G3DSA:1.10.3210.10 130 343 8.0E-47 T 29-03-2018 CB4_RS17265 16ecbec03925656528fa1b6e03eef4e6 354 SUPERFAMILY SSF52172 10 144 8.11E-11 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS17265 16ecbec03925656528fa1b6e03eef4e6 354 SMART SM00471 166 303 0.0013 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS00905 bdf02ea4fc90e976922aa331ec357228 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.687 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CB4_RS00905 bdf02ea4fc90e976922aa331ec357228 122 SMART SM01374 1 122 3.0E-85 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CB4_RS00905 bdf02ea4fc90e976922aa331ec357228 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00905 bdf02ea4fc90e976922aa331ec357228 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.4E-57 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CB4_RS00905 bdf02ea4fc90e976922aa331ec357228 122 SUPERFAMILY SSF50193 2 122 5.23E-51 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CB4_RS00905 bdf02ea4fc90e976922aa331ec357228 122 Gene3D G3DSA:2.40.150.20 1 122 1.6E-53 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CB4_RS00905 bdf02ea4fc90e976922aa331ec357228 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 7.3E-55 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CB4_RS06015 d73eee7343881c3ed594b31c0fd75017 183 Pfam PF08241 Methyltransferase domain 45 143 1.3E-4 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CB4_RS06015 d73eee7343881c3ed594b31c0fd75017 183 SUPERFAMILY SSF53335 24 173 1.66E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS06015 d73eee7343881c3ed594b31c0fd75017 183 Gene3D G3DSA:3.40.50.150 9 167 2.6E-14 T 29-03-2018 CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 Gene3D G3DSA:3.40.50.300 441 613 1.3E-31 T 29-03-2018 CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 SUPERFAMILY SSF52540 376 585 4.38E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 SUPERFAMILY SSF50249 3 167 9.42E-33 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 SMART SM00487 253 443 1.9E-34 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 Pfam PF00270 DEAD/DEAH box helicase 258 415 4.5E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 Gene3D G3DSA:3.40.50.300 237 440 5.0E-36 T 29-03-2018 CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 Pfam PF17191 RecG wedge domain 7 164 2.5E-20 T 29-03-2018 IPR033454 RecG, wedge domain CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 22 648 1.9E-245 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 SMART SM00490 488 573 6.9E-22 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 Pfam PF00271 Helicase conserved C-terminal domain 453 572 3.2E-18 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 SUPERFAMILY SSF52540 173 436 7.91E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08550 6ae58bd3bd9061a94b86106039b86aee 682 Gene3D G3DSA:2.40.50.140 41 138 1.2E-8 T 29-03-2018 CB4_RS12710 a71d3cfde97f1e4f0a8a7b2fdebb552f 52 Gene3D G3DSA:1.10.1220.10 8 46 3.6E-9 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CB4_RS12710 a71d3cfde97f1e4f0a8a7b2fdebb552f 52 SUPERFAMILY SSF47598 10 47 8.26E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CB4_RS12710 a71d3cfde97f1e4f0a8a7b2fdebb552f 52 Pfam PF07878 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 9 38 3.1E-7 T 29-03-2018 IPR012869 CopG-like ribbon-helix-helix domain CB4_RS08250 a1450191eded3d634762120b7e32dcb8 363 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 9 359 3.8E-155 T 29-03-2018 IPR013438 Sporulation stage V, protein E CB4_RS08250 a1450191eded3d634762120b7e32dcb8 363 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 9 360 7.9E-124 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CB4_RS08250 a1450191eded3d634762120b7e32dcb8 363 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 319 343 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CB4_RS08250 a1450191eded3d634762120b7e32dcb8 363 Pfam PF01098 Cell cycle protein 12 362 1.5E-118 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CB4_RS05970 9142befe1d054a1a324af7da4943e3f8 606 Pfam PF13520 Amino acid permease 25 442 5.1E-27 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS02870 e767b11b30cc148f725c377a7043ede0 203 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 40 165 1.9E-48 T 29-03-2018 IPR014202 Sporulation stage II, protein R CB4_RS02870 e767b11b30cc148f725c377a7043ede0 203 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 9 169 1.8E-56 T 29-03-2018 IPR014202 Sporulation stage II, protein R CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 SUPERFAMILY SSF82679 2 114 3.79E-43 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 SMART SM00738 2 113 5.3E-55 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 Gene3D G3DSA:2.30.30.30 119 177 4.2E-18 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 Gene3D G3DSA:3.30.70.940 2 117 4.1E-46 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 3.5E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 3.5E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 3.5E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 28.667 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 3.5E-67 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 Pfam PF02357 Transcription termination factor nusG 3 110 2.5E-30 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 SMART SM00739 123 150 0.0059 T 29-03-2018 IPR005824 KOW CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CB4_RS01165 a8ef096bcf90e4d4200f70c4e4095fcc 177 SUPERFAMILY SSF50104 121 177 9.03E-18 T 29-03-2018 IPR008991 Translation protein SH3-like domain CB4_RS13400 ebcae5af3607e4f80257dee8cb49ce03 101 SUPERFAMILY SSF54909 1 98 3.93E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CB4_RS13400 ebcae5af3607e4f80257dee8cb49ce03 101 Gene3D G3DSA:3.30.70.100 3 99 1.4E-18 T 29-03-2018 CB4_RS13400 ebcae5af3607e4f80257dee8cb49ce03 101 Pfam PF07978 NIPSNAP 6 99 1.4E-23 T 29-03-2018 IPR012577 NIPSNAP CB4_RS20305 cb2a5f4dcafc53c31d3530ebad0692dd 475 SUPERFAMILY SSF103473 8 191 1.15E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS20305 cb2a5f4dcafc53c31d3530ebad0692dd 475 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 436 5.9E-76 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CB4_RS20305 cb2a5f4dcafc53c31d3530ebad0692dd 475 SUPERFAMILY SSF103473 211 471 2.35E-30 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS20305 cb2a5f4dcafc53c31d3530ebad0692dd 475 Gene3D G3DSA:1.20.1250.20 255 473 1.9E-29 T 29-03-2018 CB4_RS20305 cb2a5f4dcafc53c31d3530ebad0692dd 475 Pfam PF07690 Major Facilitator Superfamily 21 412 3.4E-52 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS20305 cb2a5f4dcafc53c31d3530ebad0692dd 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 4.3E-14 T 29-03-2018 CB4_RS20305 cb2a5f4dcafc53c31d3530ebad0692dd 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 206 224 4.3E-14 T 29-03-2018 CB4_RS20305 cb2a5f4dcafc53c31d3530ebad0692dd 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 19 43 4.3E-14 T 29-03-2018 CB4_RS20305 cb2a5f4dcafc53c31d3530ebad0692dd 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 4.3E-14 T 29-03-2018 CB4_RS20305 cb2a5f4dcafc53c31d3530ebad0692dd 475 Gene3D G3DSA:1.20.1250.20 5 200 2.6E-33 T 29-03-2018 CB4_RS17690 c63f6ef1c1083166884f4c9b83e7e0d7 368 Pfam PF03734 L,D-transpeptidase catalytic domain 227 333 2.2E-13 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CB4_RS17690 c63f6ef1c1083166884f4c9b83e7e0d7 368 SUPERFAMILY SSF141523 224 334 4.58E-25 T 29-03-2018 CB4_RS17690 c63f6ef1c1083166884f4c9b83e7e0d7 368 Gene3D G3DSA:2.40.440.10 224 335 7.1E-26 T 29-03-2018 CB4_RS04245 b7eec657032f753ebbcb88a7f9340389 355 Gene3D G3DSA:3.40.50.10210 77 338 1.5E-93 T 29-03-2018 CB4_RS04245 b7eec657032f753ebbcb88a7f9340389 355 SUPERFAMILY SSF52733 11 354 5.1E-105 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CB4_RS04245 b7eec657032f753ebbcb88a7f9340389 355 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 19 354 9.7E-119 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CB4_RS04245 b7eec657032f753ebbcb88a7f9340389 355 Pfam PF02277 Phosphoribosyltransferase 16 353 8.0E-125 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CB4_RS04245 b7eec657032f753ebbcb88a7f9340389 355 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 18 355 32.108 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CB4_RS04245 b7eec657032f753ebbcb88a7f9340389 355 Gene3D G3DSA:1.10.1610.10 10 76 2.0E-30 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CB4_RS16135 df28e1adb0ae908db90c040357ea6742 257 SUPERFAMILY SSF161098 2 246 2.24E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS16135 df28e1adb0ae908db90c040357ea6742 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 246 1.9E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS16135 df28e1adb0ae908db90c040357ea6742 257 Gene3D G3DSA:1.10.3720.10 1 256 2.7E-40 T 29-03-2018 CB4_RS07345 10a9b01fbe15f24b92e9c866831f458f 402 Gene3D G3DSA:3.40.50.300 3 231 6.1E-52 T 29-03-2018 CB4_RS07345 10a9b01fbe15f24b92e9c866831f458f 402 SUPERFAMILY SSF52540 3 302 8.32E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07345 10a9b01fbe15f24b92e9c866831f458f 402 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 259 374 4.9E-26 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CB4_RS07345 10a9b01fbe15f24b92e9c866831f458f 402 Gene3D G3DSA:3.30.1220.10 242 375 9.2E-31 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CB4_RS07345 10a9b01fbe15f24b92e9c866831f458f 402 SMART SM00833 259 374 1.1E-44 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CB4_RS07345 10a9b01fbe15f24b92e9c866831f458f 402 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 212 2.1E-56 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CB4_RS15855 9cc024ad65978691a231404b09245065 222 ProDom PD076312 INHIBITOR INTRACELLULAR PROTEINASE PRECURSOR SIGNAL DOMAIN SLH S-LAYER PROTEASE BSUPI 125 200 3.0E-11 T 29-03-2018 IPR020481 Intracellular proteinase inhibitor BsuPI CB4_RS15855 9cc024ad65978691a231404b09245065 222 Pfam PF07833 Copper amine oxidase N-terminal domain 59 100 2.3E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS15855 9cc024ad65978691a231404b09245065 222 SUPERFAMILY SSF55383 68 95 1.22E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS15855 9cc024ad65978691a231404b09245065 222 Gene3D G3DSA:3.30.457.10 83 216 3.1E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS15855 9cc024ad65978691a231404b09245065 222 Gene3D G3DSA:3.30.457.10 23 82 0.0016 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS15855 9cc024ad65978691a231404b09245065 222 Pfam PF12690 Intracellular proteinase inhibitor 125 198 1.1E-18 T 29-03-2018 IPR020481 Intracellular proteinase inhibitor BsuPI CB4_RS07285 4889013bfca700f8263d57f1c74f7bb1 479 Gene3D G3DSA:3.40.640.10 129 382 1.8E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS07285 4889013bfca700f8263d57f1c74f7bb1 479 Pfam PF00155 Aminotransferase class I and II 132 472 3.6E-22 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS07285 4889013bfca700f8263d57f1c74f7bb1 479 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 1.6E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS07285 4889013bfca700f8263d57f1c74f7bb1 479 SUPERFAMILY SSF53383 89 476 5.55E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS07285 4889013bfca700f8263d57f1c74f7bb1 479 Gene3D G3DSA:1.10.10.10 6 82 4.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07285 4889013bfca700f8263d57f1c74f7bb1 479 SUPERFAMILY SSF46785 11 82 1.45E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07285 4889013bfca700f8263d57f1c74f7bb1 479 Gene3D G3DSA:3.90.1150.10 383 479 2.7E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS07285 4889013bfca700f8263d57f1c74f7bb1 479 SMART SM00345 21 80 5.3E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 SUPERFAMILY SSF103190 87 189 1.1E-14 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 Pfam PF02743 Cache domain 44 261 7.8E-27 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 SMART SM00304 596 652 11.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 SMART SM00304 299 351 7.7E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 Gene3D G3DSA:3.30.450.20 168 275 2.9E-16 T 29-03-2018 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 Gene3D G3DSA:1.10.287.950 601 656 5.5E-5 T 29-03-2018 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 Gene3D G3DSA:1.10.287.950 407 600 7.2E-51 T 29-03-2018 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 Gene3D G3DSA:1.10.287.950 310 406 9.7E-7 T 29-03-2018 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 Pfam PF00672 HAMP domain 300 347 1.5E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 408 437 1.3E-5 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 507 536 1.3E-5 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 SUPERFAMILY SSF58104 386 655 1.18E-75 T 29-03-2018 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 SUPERFAMILY SSF58104 319 353 1.18E-75 T 29-03-2018 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 SMART SM00283 380 655 2.0E-84 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 Gene3D G3DSA:3.30.450.20 32 167 2.0E-22 T 29-03-2018 CB4_RS18875 48178e1ccefd81fcc41d29f917710a52 656 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 607 4.2E-47 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS03540 abb11e37e4eb93b0e270046e2f6675f1 142 SUPERFAMILY SSF46626 20 141 2.91E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CB4_RS03540 abb11e37e4eb93b0e270046e2f6675f1 142 PIRSF PIRSF000025 13 142 3.3E-25 T 29-03-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 CB4_RS03540 abb11e37e4eb93b0e270046e2f6675f1 142 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 71 138 7.1E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CB4_RS03540 abb11e37e4eb93b0e270046e2f6675f1 142 Gene3D G3DSA:1.10.760.10 41 142 1.6E-12 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CB4_RS02065 7401891702b0b13f4500f1f8a6705d0e 265 SMART SM00849 11 191 2.3E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS02065 7401891702b0b13f4500f1f8a6705d0e 265 SUPERFAMILY SSF56281 1 231 7.08E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS02065 7401891702b0b13f4500f1f8a6705d0e 265 Pfam PF00753 Metallo-beta-lactamase superfamily 10 216 1.3E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS02065 7401891702b0b13f4500f1f8a6705d0e 265 Gene3D G3DSA:3.60.15.10 7 257 3.2E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS06550 f1ca78f51e7bae7caa5b3ed07f74e06b 195 SMART SM00471 14 142 1.4E-10 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS06550 f1ca78f51e7bae7caa5b3ed07f74e06b 195 Pfam PF01966 HD domain 18 131 1.6E-19 T 29-03-2018 IPR006674 HD domain CB4_RS06550 f1ca78f51e7bae7caa5b3ed07f74e06b 195 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 181 1.0E-59 T 29-03-2018 IPR005249 Conserved hypothetical protein CHP00488 CB4_RS06550 f1ca78f51e7bae7caa5b3ed07f74e06b 195 Gene3D G3DSA:1.10.3210.10 1 188 1.8E-33 T 29-03-2018 CB4_RS06550 f1ca78f51e7bae7caa5b3ed07f74e06b 195 SUPERFAMILY SSF109604 3 182 1.11E-37 T 29-03-2018 CB4_RS06550 f1ca78f51e7bae7caa5b3ed07f74e06b 195 TIGRFAM TIGR00277 HDIG: HDIG domain 18 111 6.4E-8 T 29-03-2018 IPR006675 HDIG domain CB4_RS15985 6dad33b1e763c15408f49928ed533e61 194 Pfam PF07670 Nucleoside recognition 43 149 2.4E-10 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CB4_RS13110 98a87c42914987f1459d1ade28689e07 275 Gene3D G3DSA:3.40.50.300 4 275 8.4E-61 T 29-03-2018 CB4_RS13110 98a87c42914987f1459d1ade28689e07 275 SUPERFAMILY SSF52540 7 256 1.36E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13110 98a87c42914987f1459d1ade28689e07 275 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS13110 98a87c42914987f1459d1ade28689e07 275 SMART SM00382 36 235 2.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13110 98a87c42914987f1459d1ade28689e07 275 Pfam PF00005 ABC transporter 28 185 9.1E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS03060 f34a091a3e35ac64fd6a78784605ffe5 445 SUPERFAMILY SSF55205 2 420 1.18E-138 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CB4_RS03060 f34a091a3e35ac64fd6a78784605ffe5 445 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 419 44.56 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS03060 f34a091a3e35ac64fd6a78784605ffe5 445 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 418 8.2E-173 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS03060 f34a091a3e35ac64fd6a78784605ffe5 445 Gene3D G3DSA:3.65.10.10 222 422 9.4E-51 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS03060 f34a091a3e35ac64fd6a78784605ffe5 445 Gene3D G3DSA:3.65.10.10 21 221 2.1E-49 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS03060 f34a091a3e35ac64fd6a78784605ffe5 445 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 3.1E-108 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS15265 5d515ac4965b4ae5ce1b0741e4e2d354 223 SUPERFAMILY SSF52540 3 217 1.78E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15265 5d515ac4965b4ae5ce1b0741e4e2d354 223 Hamap MF_00238 Cytidylate kinase [cmk]. 1 219 34.716 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CB4_RS15265 5d515ac4965b4ae5ce1b0741e4e2d354 223 TIGRFAM TIGR00017 cmk: cytidylate kinase 2 213 9.9E-79 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CB4_RS15265 5d515ac4965b4ae5ce1b0741e4e2d354 223 Pfam PF02224 Cytidylate kinase 3 216 2.7E-79 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CB4_RS15265 5d515ac4965b4ae5ce1b0741e4e2d354 223 Gene3D G3DSA:3.40.50.300 1 219 6.7E-55 T 29-03-2018 CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Pfam PF00395 S-layer homology domain 504 545 1.1E-15 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Pfam PF00395 S-layer homology domain 563 606 3.2E-13 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Pfam PF00395 S-layer homology domain 625 669 4.1E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Pfam PF12733 Cadherin-like beta sandwich domain 392 479 6.3E-17 T 29-03-2018 IPR025883 Cadherin-like beta sandwich domain CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 SUPERFAMILY SSF50998 60 200 8.11E-27 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Pfam PF13570 PQQ-like domain 106 144 1.2E-9 T 29-03-2018 IPR025666 Pyrrolo-quinoline quinone-like domain CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Pfam PF13570 PQQ-like domain 67 104 1.0E-8 T 29-03-2018 IPR025666 Pyrrolo-quinoline quinone-like domain CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Pfam PF13570 PQQ-like domain 146 183 1.8E-8 T 29-03-2018 IPR025666 Pyrrolo-quinoline quinone-like domain CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Pfam PF13360 PQQ-like domain 217 385 2.8E-19 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 SMART SM00564 242 273 8.8E-7 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 SMART SM00564 322 353 1.0E-5 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 SMART SM00564 122 153 7.9E-8 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 SMART SM00564 82 113 1.2E-6 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 SMART SM00564 282 313 9.5E-8 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 SMART SM00564 362 394 42.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 SMART SM00564 162 193 5.8E-8 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 SMART SM00564 202 233 3.5E-7 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 SUPERFAMILY SSF50998 156 411 1.1E-39 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Gene3D G3DSA:2.140.10.10 191 275 1.9E-22 T 29-03-2018 CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Gene3D G3DSA:2.140.10.10 18 190 5.1E-35 T 29-03-2018 CB4_RS03265 8828f823ef7e0994e8a465af5918d105 680 Gene3D G3DSA:2.140.10.10 276 631 3.1E-26 T 29-03-2018 CB4_RS08385 4b4ecbf4d28d0aa36373bf98bafb7371 432 Pfam PF01979 Amidohydrolase family 49 418 1.3E-43 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CB4_RS08385 4b4ecbf4d28d0aa36373bf98bafb7371 432 SUPERFAMILY SSF51338 365 427 4.17E-28 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS08385 4b4ecbf4d28d0aa36373bf98bafb7371 432 SUPERFAMILY SSF51338 1 52 4.17E-28 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS08385 4b4ecbf4d28d0aa36373bf98bafb7371 432 Gene3D G3DSA:2.30.40.10 1 66 7.5E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS08385 4b4ecbf4d28d0aa36373bf98bafb7371 432 Gene3D G3DSA:3.20.20.140 67 405 2.0E-113 T 29-03-2018 CB4_RS08385 4b4ecbf4d28d0aa36373bf98bafb7371 432 SUPERFAMILY SSF51556 53 364 6.97E-114 T 29-03-2018 IPR032466 Metal-dependent hydrolase CB4_RS08385 4b4ecbf4d28d0aa36373bf98bafb7371 432 ProSitePatterns PS00482 Dihydroorotase signature 1. 56 64 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08385 4b4ecbf4d28d0aa36373bf98bafb7371 432 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 423 46.129 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08385 4b4ecbf4d28d0aa36373bf98bafb7371 432 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS08385 4b4ecbf4d28d0aa36373bf98bafb7371 432 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 14 420 2.0E-142 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CB4_RS03705 25bd6b0acc68668fac0f706944654bf2 217 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 2 105 28.679 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CB4_RS03705 25bd6b0acc68668fac0f706944654bf2 217 SUPERFAMILY SSF101386 126 215 2.99E-26 T 29-03-2018 CB4_RS03705 25bd6b0acc68668fac0f706944654bf2 217 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 100 1.4E-32 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CB4_RS03705 25bd6b0acc68668fac0f706944654bf2 217 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 129 211 2.7E-31 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CB4_RS03705 25bd6b0acc68668fac0f706944654bf2 217 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 129 215 2.3E-16 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CB4_RS03705 25bd6b0acc68668fac0f706944654bf2 217 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 4 216 36.388 T 29-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 CB4_RS03705 25bd6b0acc68668fac0f706944654bf2 217 SUPERFAMILY SSF141734 4 107 1.07E-45 T 29-03-2018 CB4_RS03705 25bd6b0acc68668fac0f706944654bf2 217 Gene3D G3DSA:1.10.287.1080 124 217 3.3E-24 T 29-03-2018 CB4_RS03705 25bd6b0acc68668fac0f706944654bf2 217 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 125 211 20.825 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CB4_RS03705 25bd6b0acc68668fac0f706944654bf2 217 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 51 100 2.0E-18 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CB4_RS03150 a5faa654b5ae54e2ecb0b93aff77dd6b 1067 SUPERFAMILY SSF53756 707 1058 3.4E-30 T 29-03-2018 CB4_RS03150 a5faa654b5ae54e2ecb0b93aff77dd6b 1067 Pfam PF08241 Methyltransferase domain 39 134 3.7E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CB4_RS03150 a5faa654b5ae54e2ecb0b93aff77dd6b 1067 Gene3D G3DSA:3.90.550.10 423 729 2.3E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS03150 a5faa654b5ae54e2ecb0b93aff77dd6b 1067 SUPERFAMILY SSF53448 434 681 3.47E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS03150 a5faa654b5ae54e2ecb0b93aff77dd6b 1067 Pfam PF00535 Glycosyl transferase family 2 440 573 2.6E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CB4_RS03150 a5faa654b5ae54e2ecb0b93aff77dd6b 1067 Pfam PF13692 Glycosyl transferases group 1 895 1033 2.6E-26 T 29-03-2018 CB4_RS03150 a5faa654b5ae54e2ecb0b93aff77dd6b 1067 SUPERFAMILY SSF53335 16 183 1.22E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS03150 a5faa654b5ae54e2ecb0b93aff77dd6b 1067 Gene3D G3DSA:3.40.50.150 15 332 1.0E-34 T 29-03-2018 CB4_RS03150 a5faa654b5ae54e2ecb0b93aff77dd6b 1067 Gene3D G3DSA:3.40.50.2000 882 1042 4.0E-22 T 29-03-2018 CB4_RS09345 c1f439f059ba2aadb204ad7b4f91f207 314 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 26 179 3.2E-58 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CB4_RS09345 c1f439f059ba2aadb204ad7b4f91f207 314 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 236 1.1E-14 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CB4_RS09345 c1f439f059ba2aadb204ad7b4f91f207 314 Gene3D G3DSA:3.30.2350.10 3 228 1.3E-84 T 29-03-2018 CB4_RS09345 c1f439f059ba2aadb204ad7b4f91f207 314 SUPERFAMILY SSF55120 4 227 5.14E-81 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS09345 c1f439f059ba2aadb204ad7b4f91f207 314 Gene3D G3DSA:2.30.130.10 240 313 8.7E-6 T 29-03-2018 IPR002478 PUA domain GO:0003723 CB4_RS09345 c1f439f059ba2aadb204ad7b4f91f207 314 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 4 309 19.165 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS09345 c1f439f059ba2aadb204ad7b4f91f207 314 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 5 217 1.4E-80 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS13625 f2cb0a327c4f13c7f77327f3a8ffc8d7 291 Pfam PF00753 Metallo-beta-lactamase superfamily 44 239 8.9E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS13625 f2cb0a327c4f13c7f77327f3a8ffc8d7 291 SUPERFAMILY SSF56281 35 284 4.06E-54 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS13625 f2cb0a327c4f13c7f77327f3a8ffc8d7 291 SMART SM00849 46 240 7.1E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS13625 f2cb0a327c4f13c7f77327f3a8ffc8d7 291 Gene3D G3DSA:3.60.15.10 21 265 1.8E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS03250 33b247159eb100aeed46ed4a31fd25ae 524 Pfam PF04932 O-Antigen ligase 251 452 3.9E-19 T 29-03-2018 IPR007016 O-antigen ligase-related CB4_RS17560 a5e1c316db5d54163390055d0e94cdf8 759 Pfam PF03413 Peptidase propeptide and YPEB domain 404 480 0.0065 T 29-03-2018 IPR025711 PepSY domain CB4_RS17560 a5e1c316db5d54163390055d0e94cdf8 759 Pfam PF00395 S-layer homology domain 578 615 5.4E-4 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS17560 a5e1c316db5d54163390055d0e94cdf8 759 Pfam PF00395 S-layer homology domain 701 743 0.0044 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS17560 a5e1c316db5d54163390055d0e94cdf8 759 Gene3D G3DSA:3.10.450.40 49 117 0.04 T 29-03-2018 CB4_RS17560 a5e1c316db5d54163390055d0e94cdf8 759 Gene3D G3DSA:3.10.450.40 315 385 3.5E-4 T 29-03-2018 CB4_RS16090 707b87b93be5de9eb49fbb25b482f61b 330 Gene3D G3DSA:3.40.1190.20 3 328 2.4E-77 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS16090 707b87b93be5de9eb49fbb25b482f61b 330 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 34 58 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CB4_RS16090 707b87b93be5de9eb49fbb25b482f61b 330 PRINTS PR00990 Ribokinase signature 29 48 2.5E-8 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CB4_RS16090 707b87b93be5de9eb49fbb25b482f61b 330 PRINTS PR00990 Ribokinase signature 184 199 2.5E-8 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CB4_RS16090 707b87b93be5de9eb49fbb25b482f61b 330 PRINTS PR00990 Ribokinase signature 223 234 2.5E-8 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CB4_RS16090 707b87b93be5de9eb49fbb25b482f61b 330 Pfam PF00294 pfkB family carbohydrate kinase 4 315 2.3E-72 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CB4_RS16090 707b87b93be5de9eb49fbb25b482f61b 330 SUPERFAMILY SSF53613 4 321 4.37E-85 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS04425 508f560899ec99c77dcbc9e1c328d184 246 PIRSF PIRSF039085 1 241 4.9E-121 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CB4_RS04425 508f560899ec99c77dcbc9e1c328d184 246 Pfam PF00005 ABC transporter 17 165 1.6E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS04425 508f560899ec99c77dcbc9e1c328d184 246 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS04425 508f560899ec99c77dcbc9e1c328d184 246 SMART SM00382 26 221 2.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS04425 508f560899ec99c77dcbc9e1c328d184 246 Gene3D G3DSA:3.40.50.300 1 245 2.8E-77 T 29-03-2018 CB4_RS04425 508f560899ec99c77dcbc9e1c328d184 246 SUPERFAMILY SSF52540 1 235 6.78E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11525 c2f248bb7ffcf886fcf8e26fe08a061f 202 Pfam PF00395 S-layer homology domain 144 185 3.9E-12 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02905 07f5f943e34b844a52a78b03ad077100 189 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 9 179 1.4E-72 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CB4_RS02905 07f5f943e34b844a52a78b03ad077100 189 PIRSF PIRSF007510 1 182 2.2E-75 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CB4_RS02905 07f5f943e34b844a52a78b03ad077100 189 Gene3D G3DSA:3.40.50.10360 5 181 9.4E-78 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CB4_RS02905 07f5f943e34b844a52a78b03ad077100 189 SUPERFAMILY SSF110710 6 186 8.63E-74 T 29-03-2018 CB4_RS02905 07f5f943e34b844a52a78b03ad077100 189 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 19 180 1.0E-50 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CB4_RS02905 07f5f943e34b844a52a78b03ad077100 189 Pfam PF04260 Protein of unknown function (DUF436) 11 179 1.0E-74 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CB4_RS02905 07f5f943e34b844a52a78b03ad077100 189 Hamap MF_00800 UPF0340 protein . 1 189 89.851 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CB4_RS16580 3c5978952a938f29e7b39ac34ff0d66c 163 SUPERFAMILY SSF158682 25 146 7.59E-13 T 29-03-2018 CB4_RS16580 3c5978952a938f29e7b39ac34ff0d66c 163 Gene3D G3DSA:1.10.3680.10 17 140 1.1E-12 T 29-03-2018 IPR029024 TerB-like CB4_RS16580 3c5978952a938f29e7b39ac34ff0d66c 163 Pfam PF04391 Protein of unknown function (DUF533) 28 136 1.6E-8 T 29-03-2018 IPR007486 Inner membrane protein YebE CB4_RS05285 ce638035962135a53a384a82f29ae6d2 160 Gene3D G3DSA:1.20.144.10 2 157 8.0E-5 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS05285 ce638035962135a53a384a82f29ae6d2 160 Pfam PF02681 Divergent PAP2 family 6 149 1.3E-51 T 29-03-2018 IPR003832 Acid phosphatase/vanadium-dependent haloperoxidase-related CB4_RS03395 3f1457d81ac733e4eca5d3f32c26d2e4 85 Gene3D G3DSA:1.10.287.1160 53 82 3.2E-12 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CB4_RS03395 3f1457d81ac733e4eca5d3f32c26d2e4 85 Pfam PF04316 Anti-sigma-28 factor, FlgM 32 81 3.7E-14 T 29-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal CB4_RS03395 3f1457d81ac733e4eca5d3f32c26d2e4 85 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 3 84 8.9E-15 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CB4_RS03395 3f1457d81ac733e4eca5d3f32c26d2e4 85 SUPERFAMILY SSF101498 1 84 5.23E-17 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 SUPERFAMILY SSF51905 98 262 4.95E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 SUPERFAMILY SSF51905 7 67 4.95E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 Gene3D G3DSA:3.50.50.60 6 266 2.0E-70 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 SMART SM01228 546 617 5.7E-44 T 29-03-2018 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 622 4.4E-289 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 624 42.861 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 Pfam PF13932 GidA associated domain 402 616 4.9E-79 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 2.4E-6 T 29-03-2018 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 2.4E-6 T 29-03-2018 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 Pfam PF01134 Glucose inhibited division protein A 9 399 5.4E-170 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.6E-5 T 29-03-2018 CB4_RS01940 d86fc2c6770c7d35f8cee709d72a3d13 627 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 3.6E-5 T 29-03-2018 CB4_RS12820 fbe0798c3f7a472d5a3bc3d0c4408398 313 Gene3D G3DSA:3.30.530.20 152 313 3.0E-19 T 29-03-2018 IPR023393 START-like domain CB4_RS12820 fbe0798c3f7a472d5a3bc3d0c4408398 313 SUPERFAMILY SSF55961 165 306 9.52E-36 T 29-03-2018 CB4_RS12820 fbe0798c3f7a472d5a3bc3d0c4408398 313 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 143 1.1E-24 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CB4_RS12820 fbe0798c3f7a472d5a3bc3d0c4408398 313 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 177 304 9.6E-19 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CB4_RS12820 fbe0798c3f7a472d5a3bc3d0c4408398 313 Gene3D G3DSA:3.30.530.20 3 149 8.1E-21 T 29-03-2018 IPR023393 START-like domain CB4_RS12820 fbe0798c3f7a472d5a3bc3d0c4408398 313 SUPERFAMILY SSF55961 7 145 5.92E-32 T 29-03-2018 CB4_RS05715 30a06818d8eb73282f0f0d5834104d58 442 SUPERFAMILY SSF53244 299 435 2.2E-29 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS05715 30a06818d8eb73282f0f0d5834104d58 442 Pfam PF08245 Mur ligase middle domain 47 273 1.1E-13 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS05715 30a06818d8eb73282f0f0d5834104d58 442 SUPERFAMILY SSF53623 4 299 3.21E-91 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS05715 30a06818d8eb73282f0f0d5834104d58 442 TIGRFAM TIGR01499 folC: bifunctional protein FolC 25 431 6.1E-118 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CB4_RS05715 30a06818d8eb73282f0f0d5834104d58 442 Pfam PF02875 Mur ligase family, glutamate ligase domain 299 379 5.7E-11 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS05715 30a06818d8eb73282f0f0d5834104d58 442 PIRSF PIRSF001563 1 438 2.0E-145 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CB4_RS05715 30a06818d8eb73282f0f0d5834104d58 442 Gene3D G3DSA:3.90.190.20 305 442 9.4E-28 T 29-03-2018 CB4_RS05715 30a06818d8eb73282f0f0d5834104d58 442 Gene3D G3DSA:3.40.1190.10 4 300 3.4E-84 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS08135 6730583b47da89410c569c7a3c6e0e52 444 SMART SM00670 3 135 1.2E-14 T 29-03-2018 IPR002716 PIN domain CB4_RS08135 6730583b47da89410c569c7a3c6e0e52 444 SUPERFAMILY SSF88723 3 64 2.55E-11 T 29-03-2018 IPR029060 PIN domain-like CB4_RS08135 6730583b47da89410c569c7a3c6e0e52 444 SUPERFAMILY SSF88723 94 149 2.55E-11 T 29-03-2018 IPR029060 PIN domain-like CB4_RS08135 6730583b47da89410c569c7a3c6e0e52 444 Gene3D G3DSA:3.40.50.300 233 441 4.1E-23 T 29-03-2018 CB4_RS08135 6730583b47da89410c569c7a3c6e0e52 444 Pfam PF13638 PIN domain 5 147 3.0E-31 T 29-03-2018 IPR002716 PIN domain CB4_RS08135 6730583b47da89410c569c7a3c6e0e52 444 SUPERFAMILY SSF52540 234 422 4.85E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08135 6730583b47da89410c569c7a3c6e0e52 444 Pfam PF02562 PhoH-like protein 235 440 1.3E-55 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CB4_RS08135 6730583b47da89410c569c7a3c6e0e52 444 Gene3D G3DSA:3.40.50.1010 1 179 1.4E-34 T 29-03-2018 IPR029060 PIN domain-like CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 108 599 1.5E-246 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 SMART SM00382 192 331 6.7E-26 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 SUPERFAMILY SSF52540 152 400 1.77E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 SUPERFAMILY SSF140990 410 602 2.35E-74 T 29-03-2018 CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 601 38.813 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 Gene3D G3DSA:1.10.8.60 341 422 8.7E-23 T 29-03-2018 CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 Pfam PF06480 FtsH Extracellular 10 95 2.3E-11 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 ProSitePatterns PS00674 AAA-protein family signature. 299 317 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 Gene3D G3DSA:3.40.50.300 134 340 8.1E-66 T 29-03-2018 CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 Pfam PF01434 Peptidase family M41 390 598 7.7E-86 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CB4_RS01400 10df2020a71dcdb0bb2f725e03ff4e1f 646 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 196 328 1.1E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS02005 f010acaf5517b692d69567014d68c86d 161 Hamap MF_00984 Single-stranded DNA-binding protein. 1 106 34.695 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CB4_RS02005 f010acaf5517b692d69567014d68c86d 161 SUPERFAMILY SSF50249 1 161 1.61E-56 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS02005 f010acaf5517b692d69567014d68c86d 161 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 161 2.2E-46 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CB4_RS02005 f010acaf5517b692d69567014d68c86d 161 Gene3D G3DSA:2.40.50.140 1 109 3.1E-41 T 29-03-2018 CB4_RS02005 f010acaf5517b692d69567014d68c86d 161 Pfam PF00436 Single-strand binding protein family 1 102 1.8E-38 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CB4_RS15770 5d4cbec34b1af0100df3e564c32b31f4 61 Gene3D G3DSA:1.10.10.10 1 57 1.1E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09760 64bb096da0faa08e0586043594d0fdcf 585 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 205 294 2.2E-18 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CB4_RS09760 64bb096da0faa08e0586043594d0fdcf 585 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 26 150 7.3E-11 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CB4_RS09760 64bb096da0faa08e0586043594d0fdcf 585 Gene3D G3DSA:1.10.800.10 3 319 2.2E-80 T 29-03-2018 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 CB4_RS09760 64bb096da0faa08e0586043594d0fdcf 585 SUPERFAMILY SSF56534 204 301 7.19E-80 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CB4_RS09760 64bb096da0faa08e0586043594d0fdcf 585 SUPERFAMILY SSF56534 13 158 7.19E-80 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CB4_RS09700 a77b0dbb50c5c4ad101ffb3c3f9b6038 332 SUPERFAMILY SSF50978 46 178 8.97E-8 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 CB4_RS09700 a77b0dbb50c5c4ad101ffb3c3f9b6038 332 Gene3D G3DSA:2.130.10.10 11 221 8.5E-9 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS01350 55919fba34ad24e88def7b34806f6739 282 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 55 68 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS01350 55919fba34ad24e88def7b34806f6739 282 Gene3D G3DSA:3.20.20.20 8 281 2.7E-109 T 29-03-2018 CB4_RS01350 55919fba34ad24e88def7b34806f6739 282 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 21 36 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS01350 55919fba34ad24e88def7b34806f6739 282 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 21 271 5.4E-100 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CB4_RS01350 55919fba34ad24e88def7b34806f6739 282 Pfam PF00809 Pterin binding enzyme 22 256 6.3E-87 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS01350 55919fba34ad24e88def7b34806f6739 282 SUPERFAMILY SSF51717 10 272 5.36E-101 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CB4_RS01685 1cae7b7cb9c15f832f9b97afb4685e94 196 Gene3D G3DSA:1.10.357.10 60 192 2.4E-18 T 29-03-2018 CB4_RS01685 1cae7b7cb9c15f832f9b97afb4685e94 196 Pfam PF08359 YsiA-like protein, C-terminal region 63 188 3.0E-5 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal CB4_RS01685 1cae7b7cb9c15f832f9b97afb4685e94 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 3.9E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS01685 1cae7b7cb9c15f832f9b97afb4685e94 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS01685 1cae7b7cb9c15f832f9b97afb4685e94 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS01685 1cae7b7cb9c15f832f9b97afb4685e94 196 Gene3D G3DSA:1.10.10.60 1 59 5.9E-16 T 29-03-2018 CB4_RS01685 1cae7b7cb9c15f832f9b97afb4685e94 196 SUPERFAMILY SSF46689 3 71 3.09E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS01685 1cae7b7cb9c15f832f9b97afb4685e94 196 SUPERFAMILY SSF48498 78 190 2.2E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS07870 3be826c2ed006c45c9f3665bc6d623f6 150 Gene3D G3DSA:3.40.50.9100 1 146 1.3E-70 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CB4_RS07870 3be826c2ed006c45c9f3665bc6d623f6 150 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 150 74.652 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CB4_RS07870 3be826c2ed006c45c9f3665bc6d623f6 150 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 142 1.2E-66 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CB4_RS07870 3be826c2ed006c45c9f3665bc6d623f6 150 PIRSF PIRSF001399 1 146 9.0E-66 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CB4_RS07870 3be826c2ed006c45c9f3665bc6d623f6 150 SUPERFAMILY SSF52304 3 145 2.09E-64 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CB4_RS07870 3be826c2ed006c45c9f3665bc6d623f6 150 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 136 4.0E-47 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CB4_RS07870 3be826c2ed006c45c9f3665bc6d623f6 150 Pfam PF01220 Dehydroquinase class II 3 139 1.2E-65 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CB4_RS07870 3be826c2ed006c45c9f3665bc6d623f6 150 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 SUPERFAMILY SSF109604 338 491 6.99E-18 T 29-03-2018 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 4 690 27.077 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 Gene3D G3DSA:1.10.730.10 572 681 9.3E-10 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 Pfam PF05746 DALR anticodon binding domain 589 677 3.1E-5 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 316 332 1.2E-37 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 244 259 1.2E-37 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 51 63 1.2E-37 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 395 414 1.2E-37 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 8 21 1.2E-37 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 7 555 8.3E-216 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 Gene3D G3DSA:1.10.3210.10 333 571 0.0017 T 29-03-2018 CB4_RS07135 e70f5220ecca41f413b6e9821ff0dec5 693 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 4 691 1.5E-249 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CB4_RS12250 e2cf87659fd0a3c941bc15af978d1a09 113 Pfam PF11155 Domain of unknown function (DUF2935) 2 103 1.7E-11 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CB4_RS12250 e2cf87659fd0a3c941bc15af978d1a09 113 SUPERFAMILY SSF158430 1 104 4.88E-11 T 29-03-2018 CB4_RS19405 16480c406d487c3e46fbb044662b8ef6 385 Pfam PF01385 Probable transposase 169 294 5.8E-11 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS19405 16480c406d487c3e46fbb044662b8ef6 385 Pfam PF07282 Putative transposase DNA-binding domain 308 376 5.6E-21 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS19405 16480c406d487c3e46fbb044662b8ef6 385 Pfam PF12323 Helix-turn-helix domain 1 45 1.2E-18 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 SUPERFAMILY SSF51998 9 488 1.53E-150 T 29-03-2018 CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 PRINTS PR01183 Ribonucleotide reductase large chain signature 307 330 1.8E-41 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 PRINTS PR01183 Ribonucleotide reductase large chain signature 49 68 1.8E-41 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 PRINTS PR01183 Ribonucleotide reductase large chain signature 241 264 1.8E-41 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 PRINTS PR01183 Ribonucleotide reductase large chain signature 190 201 1.8E-41 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 PRINTS PR01183 Ribonucleotide reductase large chain signature 368 395 1.8E-41 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 PRINTS PR01183 Ribonucleotide reductase large chain signature 279 301 1.8E-41 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 Gene3D G3DSA:3.20.70.20 7 491 1.2E-137 T 29-03-2018 CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 9 487 3.5E-139 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 357 379 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS09785 198fa7944240639376cc567f613ecbfa 498 Pfam PF02867 Ribonucleotide reductase, barrel domain 9 483 2.3E-129 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS07735 fbd586f91d65881a19dacfe0e9aa2708 194 Gene3D G3DSA:2.60.120.10 12 128 2.1E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS07735 fbd586f91d65881a19dacfe0e9aa2708 194 SUPERFAMILY SSF51206 6 140 8.64E-23 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CB4_RS07735 fbd586f91d65881a19dacfe0e9aa2708 194 Pfam PF00027 Cyclic nucleotide-binding domain 30 110 1.0E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS07735 fbd586f91d65881a19dacfe0e9aa2708 194 Gene3D G3DSA:1.10.10.10 129 192 2.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07735 fbd586f91d65881a19dacfe0e9aa2708 194 SMART SM00100 11 130 4.3E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CB4_RS16035 1fd74678ff926e7339b97675617e9165 216 Gene3D G3DSA:2.40.30.20 101 205 2.0E-34 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS16035 1fd74678ff926e7339b97675617e9165 216 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 201 9.9E-75 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16035 1fd74678ff926e7339b97675617e9165 216 SUPERFAMILY SSF63380 93 198 3.74E-34 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CB4_RS16035 1fd74678ff926e7339b97675617e9165 216 Gene3D G3DSA:2.40.30.20 1 92 1.0E-29 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS16035 1fd74678ff926e7339b97675617e9165 216 Pfam PF00677 Lumazine binding domain 3 86 2.9E-24 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16035 1fd74678ff926e7339b97675617e9165 216 Pfam PF00677 Lumazine binding domain 99 183 1.1E-24 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS16035 1fd74678ff926e7339b97675617e9165 216 SUPERFAMILY SSF63380 1 88 4.51E-26 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CB4_RS16035 1fd74678ff926e7339b97675617e9165 216 PIRSF PIRSF000498 1 210 3.1E-77 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CB4_RS04725 4699d2bfce433198c4b8cef969dbcfb1 145 Gene3D G3DSA:3.90.1010.10 3 144 1.8E-52 T 29-03-2018 CB4_RS04725 4699d2bfce433198c4b8cef969dbcfb1 145 Pfam PF01592 NifU-like N terminal domain 10 131 6.1E-33 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CB4_RS04725 4699d2bfce433198c4b8cef969dbcfb1 145 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 143 6.3E-55 T 29-03-2018 CB4_RS04725 4699d2bfce433198c4b8cef969dbcfb1 145 SUPERFAMILY SSF82649 2 144 3.14E-47 T 29-03-2018 CB4_RS16950 dc8c0134ed3e5df8e2eca65907596d74 464 PIRSF PIRSF006060 6 463 1.2E-99 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS16950 dc8c0134ed3e5df8e2eca65907596d74 464 Pfam PF13520 Amino acid permease 27 428 1.9E-66 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 50 142 3.9E-42 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 Gene3D G3DSA:3.90.226.10 32 307 2.1E-61 T 29-03-2018 CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 SUPERFAMILY SSF52096 50 309 2.57E-86 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 82 93 1.7E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 107 125 1.7E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 147 160 1.7E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 191 200 1.7E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 163 176 1.7E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 128 144 1.7E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 3 310 41.491 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17165 6c8e8591090c58f6f003515d0618bc56 315 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 53 310 5.9E-114 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS01560 cab80e168f29e0fd754e74d767edd5fc 290 Gene3D G3DSA:3.30.950.10 124 237 2.1E-38 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01560 cab80e168f29e0fd754e74d767edd5fc 290 Gene3D G3DSA:1.10.10.60 240 290 6.2E-4 T 29-03-2018 CB4_RS01560 cab80e168f29e0fd754e74d767edd5fc 290 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS01560 cab80e168f29e0fd754e74d767edd5fc 290 Gene3D G3DSA:3.40.1010.10 12 123 1.8E-40 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01560 cab80e168f29e0fd754e74d767edd5fc 290 SUPERFAMILY SSF53790 12 232 1.57E-77 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01560 cab80e168f29e0fd754e74d767edd5fc 290 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 14 234 37.735 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS01560 cab80e168f29e0fd754e74d767edd5fc 290 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 15 289 3.0E-76 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS01560 cab80e168f29e0fd754e74d767edd5fc 290 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 213 1.9E-24 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CB4_RS01560 cab80e168f29e0fd754e74d767edd5fc 290 PIRSF PIRSF005917 4 290 8.6E-102 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS08600 fbc648691f2fd9c96096ebefe1957caf 202 Pfam PF08220 DeoR-like helix-turn-helix domain 14 51 1.2E-4 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CB4_RS08600 fbc648691f2fd9c96096ebefe1957caf 202 Hamap MF_01814 Transcription factor FapR [fapR]. 7 191 35.251 T 29-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CB4_RS08600 fbc648691f2fd9c96096ebefe1957caf 202 SUPERFAMILY SSF46785 11 61 1.52E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08600 fbc648691f2fd9c96096ebefe1957caf 202 Gene3D G3DSA:1.10.10.10 4 67 1.4E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08600 fbc648691f2fd9c96096ebefe1957caf 202 Gene3D G3DSA:3.10.129.10 68 190 8.3E-21 T 29-03-2018 CB4_RS08600 fbc648691f2fd9c96096ebefe1957caf 202 SUPERFAMILY SSF54637 79 185 6.79E-23 T 29-03-2018 IPR029069 HotDog domain CB4_RS08600 fbc648691f2fd9c96096ebefe1957caf 202 Pfam PF03061 Thioesterase superfamily 114 177 1.1E-6 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS08600 fbc648691f2fd9c96096ebefe1957caf 202 PIRSF PIRSF037733 6 193 5.3E-81 T 29-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CB4_RS01670 e8f5187cdd0bab75ddb0f09e0c661248 383 Gene3D G3DSA:3.60.40.10 124 377 4.5E-24 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS01670 e8f5187cdd0bab75ddb0f09e0c661248 383 SMART SM00331 160 376 2.5E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS01670 e8f5187cdd0bab75ddb0f09e0c661248 383 SUPERFAMILY SSF81606 195 374 3.01E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS01670 e8f5187cdd0bab75ddb0f09e0c661248 383 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 184 376 3.9E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS08560 6f6ca91827d034bb74dff906f2e69248 184 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CB4_RS08560 6f6ca91827d034bb74dff906f2e69248 184 Gene3D G3DSA:3.40.50.150 1 184 1.2E-33 T 29-03-2018 CB4_RS08560 6f6ca91827d034bb74dff906f2e69248 184 PIRSF PIRSF004553 1 183 7.8E-50 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CB4_RS08560 6f6ca91827d034bb74dff906f2e69248 184 SUPERFAMILY SSF53335 1 181 5.77E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS08560 6f6ca91827d034bb74dff906f2e69248 184 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 182 5.6E-53 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CB4_RS08560 6f6ca91827d034bb74dff906f2e69248 184 Pfam PF03602 Conserved hypothetical protein 95 1 181 2.9E-57 T 29-03-2018 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 Pfam PF00750 tRNA synthetases class I (R) 111 405 2.1E-30 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 Gene3D G3DSA:3.40.50.620 107 366 3.9E-59 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 Pfam PF05746 DALR anticodon binding domain 437 556 1.5E-37 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 SMART SM01016 9 95 2.7E-36 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 556 27.906 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 5.2E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 5.2E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 5.2E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 5.2E-24 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 Gene3D G3DSA:3.30.1360.70 3 106 8.0E-35 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 SMART SM00836 437 556 5.1E-59 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 94 1.3E-26 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 7 556 8.5E-162 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 SUPERFAMILY SSF52374 118 448 1.98E-96 T 29-03-2018 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 SUPERFAMILY SSF47323 432 556 5.3E-37 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 SUPERFAMILY SSF55190 4 115 2.49E-28 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CB4_RS02740 60b0a9fafa0bd63672c36fe8cce56c59 556 Gene3D G3DSA:1.10.730.10 403 556 7.1E-51 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CB4_RS12515 f69aa782302394c221829b368c524c70 389 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 255 2.0E-50 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CB4_RS12515 f69aa782302394c221829b368c524c70 389 Gene3D G3DSA:3.40.710.10 22 303 6.8E-56 T 29-03-2018 CB4_RS12515 f69aa782302394c221829b368c524c70 389 SUPERFAMILY SSF56601 1 275 3.76E-66 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS12515 f69aa782302394c221829b368c524c70 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 111 128 3.4E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS12515 f69aa782302394c221829b368c524c70 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 63 74 3.4E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS12515 f69aa782302394c221829b368c524c70 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 138 151 3.4E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS00030 1115f95289ae99c4fe9b03f758d5bab6 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 115 2.7E-51 T 29-03-2018 IPR014204 Sporulation stage V, protein AE CB4_RS00030 1115f95289ae99c4fe9b03f758d5bab6 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 111 2.9E-41 T 29-03-2018 IPR005562 SpoVA CB4_RS11035 853e7bb8cda77c4b69d5f3d482d36153 348 SMART SM00387 248 341 8.6E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS11035 853e7bb8cda77c4b69d5f3d482d36153 348 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 248 338 1.3E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS11035 853e7bb8cda77c4b69d5f3d482d36153 348 Gene3D G3DSA:3.30.565.10 210 347 8.6E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS11035 853e7bb8cda77c4b69d5f3d482d36153 348 PIRSF PIRSF037431 2 347 3.9E-123 T 29-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 CB4_RS11035 853e7bb8cda77c4b69d5f3d482d36153 348 Pfam PF07730 Histidine kinase 145 209 2.9E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CB4_RS11035 853e7bb8cda77c4b69d5f3d482d36153 348 SUPERFAMILY SSF55874 219 338 1.7E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS00255 000768f0a331c96afc9ff5ce32e0146c 462 Pfam PF00324 Amino acid permease 16 384 3.0E-33 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CB4_RS00255 000768f0a331c96afc9ff5ce32e0146c 462 PIRSF PIRSF006060 1 456 3.9E-74 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS18120 b2979818dc869fac61820544258d1a02 130 Gene3D G3DSA:3.10.129.10 1 122 9.6E-33 T 29-03-2018 CB4_RS18120 b2979818dc869fac61820544258d1a02 130 Pfam PF03061 Thioesterase superfamily 39 115 9.8E-19 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS18120 b2979818dc869fac61820544258d1a02 130 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 9 122 1.1E-23 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CB4_RS18120 b2979818dc869fac61820544258d1a02 130 SUPERFAMILY SSF54637 5 123 1.5E-33 T 29-03-2018 IPR029069 HotDog domain CB4_RS17825 52616c667dc58f15913d69099d204847 208 Gene3D G3DSA:3.20.20.70 3 199 1.2E-39 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS17825 52616c667dc58f15913d69099d204847 208 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 2 199 19.29 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS17825 52616c667dc58f15913d69099d204847 208 Pfam PF02581 Thiamine monophosphate synthase 17 181 2.7E-43 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS17825 52616c667dc58f15913d69099d204847 208 SUPERFAMILY SSF51391 8 197 8.76E-49 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS04215 53b0385eaaf299169d0ad02a75832b7c 529 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 48 514 2.5E-193 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS04215 53b0385eaaf299169d0ad02a75832b7c 529 PIRSF PIRSF005690 33 529 3.2E-183 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS00895 c499be61a36f8f1c675254778e6c4766 180 Pfam PF00673 ribosomal L5P family C-terminus 85 178 9.2E-42 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00895 c499be61a36f8f1c675254778e6c4766 180 Pfam PF00281 Ribosomal protein L5 25 81 2.0E-27 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00895 c499be61a36f8f1c675254778e6c4766 180 Gene3D G3DSA:3.30.1440.10 2 180 7.8E-79 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00895 c499be61a36f8f1c675254778e6c4766 180 PIRSF PIRSF002161 1 180 6.0E-68 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00895 c499be61a36f8f1c675254778e6c4766 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00895 c499be61a36f8f1c675254778e6c4766 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 44.663 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00895 c499be61a36f8f1c675254778e6c4766 180 SUPERFAMILY SSF55282 4 179 3.06E-78 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS12340 b1e2d4f44c70a206c0050e7b7f7901ff 365 Pfam PF03845 Spore germination protein 6 326 4.3E-87 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS12340 b1e2d4f44c70a206c0050e7b7f7901ff 365 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 358 4.7E-84 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS15975 dd3585bcc05e9958f6ad269d963490a8 239 Gene3D G3DSA:3.30.70.580 59 144 6.7E-22 T 29-03-2018 CB4_RS15975 dd3585bcc05e9958f6ad269d963490a8 239 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 227 1.1E-52 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CB4_RS15975 dd3585bcc05e9958f6ad269d963490a8 239 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CB4_RS15975 dd3585bcc05e9958f6ad269d963490a8 239 Gene3D G3DSA:3.10.290.10 1 58 3.1E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS15975 dd3585bcc05e9958f6ad269d963490a8 239 Pfam PF01479 S4 domain 2 44 3.8E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS15975 dd3585bcc05e9958f6ad269d963490a8 239 SUPERFAMILY SSF55120 48 235 2.4E-47 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS15975 dd3585bcc05e9958f6ad269d963490a8 239 SMART SM00363 2 70 1.1E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS15975 dd3585bcc05e9958f6ad269d963490a8 239 Gene3D G3DSA:3.30.70.1560 145 209 9.0E-26 T 29-03-2018 CB4_RS15975 dd3585bcc05e9958f6ad269d963490a8 239 SUPERFAMILY SSF55174 2 68 7.06E-15 T 29-03-2018 CB4_RS15975 dd3585bcc05e9958f6ad269d963490a8 239 Pfam PF00849 RNA pseudouridylate synthase 63 197 1.2E-19 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 Pfam PF00574 Clp protease 13 192 4.8E-88 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 2.9E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 2.9E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 2.9E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 2.9E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 2.9E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.508 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 9.0E-104 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 SUPERFAMILY SSF52096 11 194 5.68E-75 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 29-03-2018 IPR018215 ClpP, Ser active site CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 29-03-2018 IPR033135 ClpP, histidine active site CB4_RS05610 f8b3d069e53647eac5a4f057f2f4c49f 196 Gene3D G3DSA:3.90.226.10 2 194 6.6E-47 T 29-03-2018 CB4_RS04170 edadbd37d8744ea2da1d9d503d531ab3 368 Gene3D G3DSA:3.40.50.620 1 213 2.4E-72 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS04170 edadbd37d8744ea2da1d9d503d531ab3 368 Gene3D G3DSA:2.40.30.10 282 368 2.1E-30 T 29-03-2018 CB4_RS04170 edadbd37d8744ea2da1d9d503d531ab3 368 Gene3D G3DSA:2.30.30.280 214 281 2.0E-26 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CB4_RS04170 edadbd37d8744ea2da1d9d503d531ab3 368 Pfam PF03054 tRNA methyl transferase 9 360 5.4E-146 T 29-03-2018 CB4_RS04170 edadbd37d8744ea2da1d9d503d531ab3 368 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 361 41.438 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CB4_RS04170 edadbd37d8744ea2da1d9d503d531ab3 368 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 360 6.0E-140 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CB4_RS04170 edadbd37d8744ea2da1d9d503d531ab3 368 SUPERFAMILY SSF52402 7 245 1.1E-60 T 29-03-2018 CB4_RS07075 1a0ad84409268ff41526dfd0a2694207 329 SUPERFAMILY SSF82171 61 223 1.57E-6 T 29-03-2018 CB4_RS07075 1a0ad84409268ff41526dfd0a2694207 329 Gene3D G3DSA:2.130.10.10 49 303 4.6E-9 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS16240 a3fccb749ad566851c7cfdbaead4eaf1 265 Gene3D G3DSA:3.10.310.10 2 123 6.0E-35 T 29-03-2018 CB4_RS16240 a3fccb749ad566851c7cfdbaead4eaf1 265 Gene3D G3DSA:3.10.310.10 124 254 1.4E-32 T 29-03-2018 CB4_RS16240 a3fccb749ad566851c7cfdbaead4eaf1 265 PIRSF PIRSF016184 1 265 4.6E-52 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CB4_RS16240 a3fccb749ad566851c7cfdbaead4eaf1 265 Pfam PF02567 Phenazine biosynthesis-like protein 8 262 8.2E-71 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CB4_RS16240 a3fccb749ad566851c7cfdbaead4eaf1 265 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 260 1.2E-39 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CB4_RS16240 a3fccb749ad566851c7cfdbaead4eaf1 265 SUPERFAMILY SSF54506 3 264 9.58E-80 T 29-03-2018 CB4_RS05595 ca160c1b1e52078c8dcfd3985b3d5c86 179 Gene3D G3DSA:3.60.21.10 1 168 1.0E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS05595 ca160c1b1e52078c8dcfd3985b3d5c86 179 SUPERFAMILY SSF56300 1 147 2.7E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS05595 ca160c1b1e52078c8dcfd3985b3d5c86 179 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 141 7.8E-26 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CB4_RS05595 ca160c1b1e52078c8dcfd3985b3d5c86 179 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 140 5.8E-25 T 29-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CB4_RS17730 2be42033433019366f3a58f499623244 396 SUPERFAMILY SSF111369 199 388 3.79E-6 T 29-03-2018 CB4_RS17730 2be42033433019366f3a58f499623244 396 Pfam PF13533 Biotin-lipoyl like 40 85 2.8E-5 T 29-03-2018 CB4_RS17730 2be42033433019366f3a58f499623244 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 151 344 1.5E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CB4_RS17730 2be42033433019366f3a58f499623244 396 Gene3D G3DSA:2.40.50.100 38 135 4.4E-7 T 29-03-2018 CB4_RS17730 2be42033433019366f3a58f499623244 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 313 337 2.5E-10 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CB4_RS17730 2be42033433019366f3a58f499623244 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 281 302 2.5E-10 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CB4_RS17730 2be42033433019366f3a58f499623244 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 378 393 2.5E-10 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CB4_RS17730 2be42033433019366f3a58f499623244 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 48 68 2.5E-10 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CB4_RS17730 2be42033433019366f3a58f499623244 396 SUPERFAMILY SSF111369 40 122 2.75E-6 T 29-03-2018 CB4_RS17730 2be42033433019366f3a58f499623244 396 Gene3D G3DSA:1.20.1600.10 188 378 1.4E-12 T 29-03-2018 CB4_RS09615 d121eb61e9c07ea465d4f0fdcf44b42d 629 Gene3D G3DSA:3.40.50.1820 399 606 5.1E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS09615 d121eb61e9c07ea465d4f0fdcf44b42d 629 SUPERFAMILY SSF53474 400 580 1.06E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS09615 d121eb61e9c07ea465d4f0fdcf44b42d 629 Pfam PF01764 Lipase (class 3) 456 579 6.6E-23 T 29-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 CB4_RS09740 9275d35fad0b5107310987b586a700bf 167 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 137 4.5E-30 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CB4_RS09740 9275d35fad0b5107310987b586a700bf 167 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CB4_RS09740 9275d35fad0b5107310987b586a700bf 167 SUPERFAMILY SSF46785 2 141 8.28E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS09740 9275d35fad0b5107310987b586a700bf 167 Pfam PF02082 Transcriptional regulator 1 83 1.8E-22 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CB4_RS09740 9275d35fad0b5107310987b586a700bf 167 Gene3D G3DSA:1.10.10.10 1 151 1.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00440 a3ba818ca323312fd9de87864e3bce0c 382 PIRSF PIRSF001434 1 380 6.7E-143 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS00440 a3ba818ca323312fd9de87864e3bce0c 382 SUPERFAMILY SSF53383 5 377 1.11E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS00440 a3ba818ca323312fd9de87864e3bce0c 382 Gene3D G3DSA:3.90.1150.10 246 382 2.2E-47 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS00440 a3ba818ca323312fd9de87864e3bce0c 382 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 2.1E-151 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS00440 a3ba818ca323312fd9de87864e3bce0c 382 Gene3D G3DSA:3.40.640.10 1 245 7.4E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS09190 d115b8d819ba45878c49b1dcd2bde657 677 PIRSF PIRSF005419 1 677 9.9E-260 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CB4_RS09190 d115b8d819ba45878c49b1dcd2bde657 677 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 126 149 - T 29-03-2018 IPR025505 FHIPEP conserved site CB4_RS09190 d115b8d819ba45878c49b1dcd2bde657 677 Pfam PF00771 FHIPEP family 15 667 5.7E-275 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CB4_RS09190 d115b8d819ba45878c49b1dcd2bde657 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 6.3E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CB4_RS09190 d115b8d819ba45878c49b1dcd2bde657 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 6.3E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CB4_RS09190 d115b8d819ba45878c49b1dcd2bde657 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 6.3E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CB4_RS09190 d115b8d819ba45878c49b1dcd2bde657 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 6.3E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CB4_RS09190 d115b8d819ba45878c49b1dcd2bde657 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 6.3E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CB4_RS09190 d115b8d819ba45878c49b1dcd2bde657 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 6.3E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CB4_RS09190 d115b8d819ba45878c49b1dcd2bde657 677 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 4 675 1.9E-270 T 29-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 CB4_RS10065 3a30ea8e036494f2cbc443839175da28 319 SUPERFAMILY SSF55729 157 318 4.49E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS10065 3a30ea8e036494f2cbc443839175da28 319 Gene3D G3DSA:3.40.630.30 10 148 2.0E-4 T 29-03-2018 CB4_RS10065 3a30ea8e036494f2cbc443839175da28 319 Gene3D G3DSA:3.40.630.30 149 311 4.2E-28 T 29-03-2018 CB4_RS10065 3a30ea8e036494f2cbc443839175da28 319 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 70 315 2.6E-16 T 29-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CB4_RS07290 c90e5276c28ab8a6bc8d366c18625d3f 358 SUPERFAMILY SSF51412 5 78 5.19E-64 T 29-03-2018 CB4_RS07290 c90e5276c28ab8a6bc8d366c18625d3f 358 SUPERFAMILY SSF51412 106 349 5.19E-64 T 29-03-2018 CB4_RS07290 c90e5276c28ab8a6bc8d366c18625d3f 358 Pfam PF03060 Nitronate monooxygenase 12 349 5.8E-95 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CB4_RS07290 c90e5276c28ab8a6bc8d366c18625d3f 358 Gene3D G3DSA:3.20.20.70 2 358 5.2E-57 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS13495 2bcb36c92bf7f0765f33894808c9de3c 260 SUPERFAMILY SSF56784 1 64 9.04E-43 T 29-03-2018 IPR023214 HAD-like domain CB4_RS13495 2bcb36c92bf7f0765f33894808c9de3c 260 SUPERFAMILY SSF56784 95 258 9.04E-43 T 29-03-2018 IPR023214 HAD-like domain CB4_RS13495 2bcb36c92bf7f0765f33894808c9de3c 260 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 133 225 6.5E-15 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS13495 2bcb36c92bf7f0765f33894808c9de3c 260 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 130 231 8.8E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CB4_RS13495 2bcb36c92bf7f0765f33894808c9de3c 260 Gene3D G3DSA:3.40.50.1000 1 112 0.0064 T 29-03-2018 IPR023214 HAD-like domain CB4_RS13495 2bcb36c92bf7f0765f33894808c9de3c 260 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 231 1.2E-24 T 29-03-2018 IPR023214 HAD-like domain CB4_RS13495 2bcb36c92bf7f0765f33894808c9de3c 260 Gene3D G3DSA:3.40.50.1000 113 260 6.8E-29 T 29-03-2018 IPR023214 HAD-like domain CB4_RS02185 dc1cb9d0a06b7c3ced596ab76f054cce 114 Pfam PF05154 TM2 domain 25 73 4.4E-18 T 29-03-2018 IPR007829 TM2 domain CB4_RS13595 a274d54088e2aaf7334cfb06b1cbfd4e 108 PRINTS PR00344 Bacterial sensor protein C-terminal signature 30 44 2.9E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13595 a274d54088e2aaf7334cfb06b1cbfd4e 108 PRINTS PR00344 Bacterial sensor protein C-terminal signature 48 58 2.9E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13595 a274d54088e2aaf7334cfb06b1cbfd4e 108 PRINTS PR00344 Bacterial sensor protein C-terminal signature 65 83 2.9E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13595 a274d54088e2aaf7334cfb06b1cbfd4e 108 PRINTS PR00344 Bacterial sensor protein C-terminal signature 89 102 2.9E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13595 a274d54088e2aaf7334cfb06b1cbfd4e 108 SUPERFAMILY SSF55874 2 101 2.1E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13595 a274d54088e2aaf7334cfb06b1cbfd4e 108 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 5 102 3.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13595 a274d54088e2aaf7334cfb06b1cbfd4e 108 SMART SM00387 1 105 8.7E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13595 a274d54088e2aaf7334cfb06b1cbfd4e 108 Gene3D G3DSA:3.30.565.10 1 106 1.4E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS17865 d854bc0fe78fb48c1a40abc75f688d10 399 Pfam PF07690 Major Facilitator Superfamily 11 235 5.3E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS17865 d854bc0fe78fb48c1a40abc75f688d10 399 Gene3D G3DSA:1.20.1250.20 204 396 2.3E-30 T 29-03-2018 CB4_RS17865 d854bc0fe78fb48c1a40abc75f688d10 399 Pfam PF05977 Transmembrane secretion effector 258 382 6.3E-5 T 29-03-2018 IPR010290 Transmembrane secretion effector CB4_RS17865 d854bc0fe78fb48c1a40abc75f688d10 399 Gene3D G3DSA:1.20.1250.20 3 203 3.1E-38 T 29-03-2018 CB4_RS17865 d854bc0fe78fb48c1a40abc75f688d10 399 SUPERFAMILY SSF103473 5 391 8.72E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS17865 d854bc0fe78fb48c1a40abc75f688d10 399 PRINTS PR01035 Tetracycline resistance protein signature 253 273 2.2E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS17865 d854bc0fe78fb48c1a40abc75f688d10 399 PRINTS PR01035 Tetracycline resistance protein signature 107 128 2.2E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS17865 d854bc0fe78fb48c1a40abc75f688d10 399 PRINTS PR01035 Tetracycline resistance protein signature 137 159 2.2E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS17865 d854bc0fe78fb48c1a40abc75f688d10 399 PRINTS PR01035 Tetracycline resistance protein signature 17 33 2.2E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CB4_RS00810 07610be4ba92adedc6586a351bf6352b 283 SMART SM00382 35 221 9.2E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS00810 07610be4ba92adedc6586a351bf6352b 283 SUPERFAMILY SSF52540 8 234 4.46E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00810 07610be4ba92adedc6586a351bf6352b 283 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 9 277 1.5E-113 T 29-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 CB4_RS00810 07610be4ba92adedc6586a351bf6352b 283 Pfam PF00005 ABC transporter 27 173 6.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS00810 07610be4ba92adedc6586a351bf6352b 283 Gene3D G3DSA:3.40.50.300 5 244 3.3E-64 T 29-03-2018 CB4_RS00810 07610be4ba92adedc6586a351bf6352b 283 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS11940 9d9a3a29c8f13507f42663be3220dcf5 517 SUPERFAMILY SSF53041 6 160 3.14E-26 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS11940 9d9a3a29c8f13507f42663be3220dcf5 517 Pfam PF00239 Resolvase, N terminal domain 6 160 6.5E-29 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS11940 9d9a3a29c8f13507f42663be3220dcf5 517 Gene3D G3DSA:3.40.50.1390 1 166 6.0E-36 T 29-03-2018 CB4_RS11940 9d9a3a29c8f13507f42663be3220dcf5 517 Pfam PF13408 Recombinase zinc beta ribbon domain 313 371 9.1E-12 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain CB4_RS11940 9d9a3a29c8f13507f42663be3220dcf5 517 Pfam PF07508 Recombinase 184 298 2.2E-21 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CB4_RS11940 9d9a3a29c8f13507f42663be3220dcf5 517 SMART SM00857 6 160 2.3E-38 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS17150 09b2184130350fed342110efec51e850 431 Pfam PF12831 FAD dependent oxidoreductase 6 147 3.8E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17150 09b2184130350fed342110efec51e850 431 SUPERFAMILY SSF54373 182 284 1.22E-19 T 29-03-2018 CB4_RS17150 09b2184130350fed342110efec51e850 431 Gene3D G3DSA:3.50.50.60 2 168 3.5E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17150 09b2184130350fed342110efec51e850 431 SUPERFAMILY SSF51905 284 379 5.0E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17150 09b2184130350fed342110efec51e850 431 SUPERFAMILY SSF51905 1 184 5.0E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17150 09b2184130350fed342110efec51e850 431 Gene3D G3DSA:3.30.9.10 169 336 1.7E-18 T 29-03-2018 CB4_RS17150 09b2184130350fed342110efec51e850 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.1E-8 T 29-03-2018 CB4_RS17150 09b2184130350fed342110efec51e850 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.1E-8 T 29-03-2018 CB4_RS17150 09b2184130350fed342110efec51e850 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 310 1.1E-8 T 29-03-2018 CB4_RS16940 8dea89fe80324f85a16ba6f0b690366e 272 Pfam PF01144 Coenzyme A transferase 16 232 3.4E-28 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CB4_RS16940 8dea89fe80324f85a16ba6f0b690366e 272 Gene3D G3DSA:3.40.1080.10 9 271 6.9E-45 T 29-03-2018 CB4_RS16940 8dea89fe80324f85a16ba6f0b690366e 272 SMART SM00882 16 232 8.8E-22 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CB4_RS16940 8dea89fe80324f85a16ba6f0b690366e 272 SUPERFAMILY SSF100950 11 267 4.19E-68 T 29-03-2018 CB4_RS17020 442f1050045442a265c615772ab4e231 451 Pfam PF00909 Ammonium Transporter Family 14 421 2.3E-114 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CB4_RS17020 442f1050045442a265c615772ab4e231 451 ProSitePatterns PS01219 Ammonium transporters signature. 167 192 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CB4_RS17020 442f1050045442a265c615772ab4e231 451 TIGRFAM TIGR00836 amt: ammonium transporter 11 421 3.7E-123 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CB4_RS17020 442f1050045442a265c615772ab4e231 451 SUPERFAMILY SSF111352 8 402 3.27E-110 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CB4_RS17020 442f1050045442a265c615772ab4e231 451 Gene3D G3DSA:1.10.3430.10 3 402 1.1E-122 T 29-03-2018 CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 Pfam PF01476 LysM domain 91 135 1.6E-11 T 29-03-2018 IPR018392 LysM domain CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 Pfam PF01476 LysM domain 34 65 0.0033 T 29-03-2018 IPR018392 LysM domain CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 SUPERFAMILY SSF54106 89 135 1.57E-9 T 29-03-2018 IPR018392 LysM domain CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 Gene3D G3DSA:3.10.350.10 21 78 3.1E-8 T 29-03-2018 CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 Gene3D G3DSA:3.10.350.10 80 146 6.5E-16 T 29-03-2018 CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 Gene3D G3DSA:3.90.1720.10 147 275 1.5E-34 T 29-03-2018 CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 SUPERFAMILY SSF54001 144 274 3.6E-38 T 29-03-2018 CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 SUPERFAMILY SSF54106 28 71 4.97E-6 T 29-03-2018 IPR018392 LysM domain CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 SMART SM00257 27 71 0.0083 T 29-03-2018 IPR018392 LysM domain CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 SMART SM00257 90 135 1.9E-9 T 29-03-2018 IPR018392 LysM domain CB4_RS12185 0174e5eecbea19146311f18f94d47b26 275 Pfam PF00877 NlpC/P60 family 164 267 1.2E-24 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CB4_RS11175 6aee67e6a47479e0d7e43f88b152b257 400 Gene3D G3DSA:3.40.50.2000 200 372 4.3E-30 T 29-03-2018 CB4_RS11175 6aee67e6a47479e0d7e43f88b152b257 400 Pfam PF13692 Glycosyl transferases group 1 214 352 3.6E-24 T 29-03-2018 CB4_RS11175 6aee67e6a47479e0d7e43f88b152b257 400 SUPERFAMILY SSF53756 38 370 1.26E-41 T 29-03-2018 CB4_RS10355 6ffc8dcf5f4d3c853ae7e579dadad378 710 SUPERFAMILY SSF52540 55 678 1.05E-121 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10355 6ffc8dcf5f4d3c853ae7e579dadad378 710 Gene3D G3DSA:3.40.50.300 320 696 6.3E-45 T 29-03-2018 CB4_RS10355 6ffc8dcf5f4d3c853ae7e579dadad378 710 Pfam PF00580 UvrD/REP helicase N-terminal domain 161 317 1.7E-36 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CB4_RS10355 6ffc8dcf5f4d3c853ae7e579dadad378 710 Pfam PF00580 UvrD/REP helicase N-terminal domain 58 148 8.9E-20 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CB4_RS10355 6ffc8dcf5f4d3c853ae7e579dadad378 710 Pfam PF13361 UvrD-like helicase C-terminal domain 573 673 4.8E-21 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CB4_RS10355 6ffc8dcf5f4d3c853ae7e579dadad378 710 Pfam PF13361 UvrD-like helicase C-terminal domain 323 460 2.0E-15 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CB4_RS10355 6ffc8dcf5f4d3c853ae7e579dadad378 710 Gene3D G3DSA:3.40.50.300 53 319 1.6E-53 T 29-03-2018 CB4_RS04255 03b00efd7d0b71d81cd9949e64033438 504 Gene3D G3DSA:3.40.50.880 242 490 7.6E-28 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS04255 03b00efd7d0b71d81cd9949e64033438 504 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 4 490 7.9E-174 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CB4_RS04255 03b00efd7d0b71d81cd9949e64033438 504 SUPERFAMILY SSF52540 1 230 4.2E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS04255 03b00efd7d0b71d81cd9949e64033438 504 Gene3D G3DSA:3.40.50.300 1 240 9.0E-48 T 29-03-2018 CB4_RS04255 03b00efd7d0b71d81cd9949e64033438 504 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 235 4.1E-22 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CB4_RS04255 03b00efd7d0b71d81cd9949e64033438 504 SUPERFAMILY SSF52317 255 452 5.77E-38 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS04255 03b00efd7d0b71d81cd9949e64033438 504 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 499 180.52 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CB4_RS04255 03b00efd7d0b71d81cd9949e64033438 504 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 255 443 1.9E-55 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 Gene3D G3DSA:3.40.50.450 197 300 2.0E-19 T 29-03-2018 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 SUPERFAMILY SSF53784 1 315 4.71E-117 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 1.3E-130 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 Pfam PF00365 Phosphofructokinase 3 275 6.4E-112 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 PIRSF PIRSF000532 1 319 2.3E-120 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 Gene3D G3DSA:3.40.50.450 1 196 2.8E-73 T 29-03-2018 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 46.159 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 8.1E-88 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 8.1E-88 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 8.1E-88 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 8.1E-88 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 8.1E-88 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 8.1E-88 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 8.1E-88 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 8.1E-88 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS16755 9db2b3e5331b0319f96dd3658e49c1f5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 8.1E-88 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CB4_RS08160 3938a24616c40946d3ebc60d69c45e22 118 Gene3D G3DSA:3.40.30.10 3 118 8.7E-33 T 29-03-2018 CB4_RS08160 3938a24616c40946d3ebc60d69c45e22 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 5 115 3.6E-35 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CB4_RS08160 3938a24616c40946d3ebc60d69c45e22 118 Pfam PF03960 ArsC family 21 114 4.2E-18 T 29-03-2018 IPR006660 Arsenate reductase-like CB4_RS08160 3938a24616c40946d3ebc60d69c45e22 118 SUPERFAMILY SSF52833 5 117 2.49E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 SUPERFAMILY SSF46894 149 216 2.01E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 SMART SM00448 3 117 8.4E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 Gene3D G3DSA:1.10.10.10 129 217 1.7E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 SMART SM00421 152 209 2.5E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 Gene3D G3DSA:3.40.50.2300 2 128 4.1E-33 T 29-03-2018 CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.0E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.0E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.0E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 Pfam PF00072 Response regulator receiver domain 5 117 7.2E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 SUPERFAMILY SSF52172 1 133 9.82E-32 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS17275 b91c5b69802d40e09f2069708fe6ee10 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.4E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS19950 065f1bd15f0ebf8cec1f5c23230b90d2 408 SMART SM00387 294 402 5.6E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS19950 065f1bd15f0ebf8cec1f5c23230b90d2 408 SUPERFAMILY SSF55874 263 399 1.83E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS19950 065f1bd15f0ebf8cec1f5c23230b90d2 408 Gene3D G3DSA:3.30.565.10 182 401 3.7E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS19950 065f1bd15f0ebf8cec1f5c23230b90d2 408 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 302 400 8.5E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS19950 065f1bd15f0ebf8cec1f5c23230b90d2 408 Pfam PF06580 Histidine kinase 204 284 5.2E-25 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CB4_RS19950 065f1bd15f0ebf8cec1f5c23230b90d2 408 Pfam PF07694 5TMR of 5TMR-LYT 24 178 1.3E-11 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CB4_RS12805 d4fdfa339d09914c7ab110d54a48b077 588 Pfam PF01740 STAS domain 441 541 1.2E-18 T 29-03-2018 IPR002645 STAS domain CB4_RS12805 d4fdfa339d09914c7ab110d54a48b077 588 Gene3D G3DSA:3.30.750.24 431 553 2.6E-23 T 29-03-2018 IPR002645 STAS domain CB4_RS12805 d4fdfa339d09914c7ab110d54a48b077 588 Pfam PF00916 Sulfate permease family 17 381 2.1E-87 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CB4_RS12805 d4fdfa339d09914c7ab110d54a48b077 588 SUPERFAMILY SSF52091 438 544 2.55E-19 T 29-03-2018 IPR002645 STAS domain CB4_RS12805 d4fdfa339d09914c7ab110d54a48b077 588 TIGRFAM TIGR00815 sulP: sulfate permease 9 541 2.3E-115 T 29-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.959 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 PIRSF PIRSF002133 1 137 2.1E-49 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 Gene3D G3DSA:2.40.50.140 1 140 1.6E-64 T 29-03-2018 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 SUPERFAMILY SSF50249 2 136 1.29E-49 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 5.1E-68 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 Pfam PF00164 Ribosomal protein S12/S23 37 136 2.0E-38 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 8.3E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 8.3E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 8.3E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 8.3E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 8.3E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 8.3E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS01115 0b64b62bb5bbd1d4f98023c5eb5f24fd 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS11215 5504a127bcbf5fd6ce211de7f0fc3d77 226 Gene3D G3DSA:3.40.50.20 2 82 4.4E-18 T 29-03-2018 CB4_RS11215 5504a127bcbf5fd6ce211de7f0fc3d77 226 Gene3D G3DSA:2.160.10.10 83 221 5.7E-34 T 29-03-2018 CB4_RS11215 5504a127bcbf5fd6ce211de7f0fc3d77 226 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 99 126 3.2E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS11215 5504a127bcbf5fd6ce211de7f0fc3d77 226 SUPERFAMILY SSF51161 2 225 1.12E-42 T 29-03-2018 IPR011004 Trimeric LpxA-like CB4_RS11215 5504a127bcbf5fd6ce211de7f0fc3d77 226 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 6 213 3.7E-65 T 29-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like CB4_RS05145 bae73deb81764d724fbc3df8284ddb26 162 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 19 162 2.1E-50 T 29-03-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit CB4_RS05145 bae73deb81764d724fbc3df8284ddb26 162 Pfam PF01883 Iron-sulfur cluster assembly protein 9 81 4.5E-18 T 29-03-2018 IPR002744 MIP18 family-like CB4_RS05145 bae73deb81764d724fbc3df8284ddb26 162 SUPERFAMILY SSF117916 7 102 9.48E-26 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CB4_RS05145 bae73deb81764d724fbc3df8284ddb26 162 Gene3D G3DSA:3.30.300.130 6 104 5.1E-22 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CB4_RS12700 226c063e5e665d4f38f021e157306bb7 296 SUPERFAMILY SSF56317 33 192 6.28E-7 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CB4_RS12700 226c063e5e665d4f38f021e157306bb7 296 Gene3D G3DSA:3.60.110.10 13 251 6.0E-6 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CB4_RS18665 330e3203461d2ccb9eb4fe48b2a48a53 288 Gene3D G3DSA:3.60.21.10 1 288 2.7E-79 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS18665 330e3203461d2ccb9eb4fe48b2a48a53 288 SUPERFAMILY SSF56300 1 285 2.35E-79 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS18665 330e3203461d2ccb9eb4fe48b2a48a53 288 PRINTS PR01607 Apyrase family signature 176 193 4.7E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CB4_RS18665 330e3203461d2ccb9eb4fe48b2a48a53 288 PRINTS PR01607 Apyrase family signature 195 218 4.7E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CB4_RS18665 330e3203461d2ccb9eb4fe48b2a48a53 288 PRINTS PR01607 Apyrase family signature 227 247 4.7E-19 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CB4_RS18665 330e3203461d2ccb9eb4fe48b2a48a53 288 Pfam PF00149 Calcineurin-like phosphoesterase 1 212 4.1E-14 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CB4_RS18665 330e3203461d2ccb9eb4fe48b2a48a53 288 ProSitePatterns PS00786 5'-nucleotidase signature 2. 62 73 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CB4_RS12295 af7dd2f329a3d6c2706cc21fd9048eab 315 Pfam PF12679 ABC-2 family transporter protein 3 313 4.7E-23 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CB4_RS14855 0fec21a26dd90fba826eb76bdda53a42 426 SUPERFAMILY SSF63411 10 228 1.37E-23 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CB4_RS14855 0fec21a26dd90fba826eb76bdda53a42 426 Pfam PF05193 Peptidase M16 inactive domain 185 360 1.1E-22 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CB4_RS14855 0fec21a26dd90fba826eb76bdda53a42 426 Gene3D G3DSA:3.30.830.10 30 226 4.7E-24 T 29-03-2018 CB4_RS14855 0fec21a26dd90fba826eb76bdda53a42 426 SUPERFAMILY SSF63411 253 414 1.05E-29 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CB4_RS14855 0fec21a26dd90fba826eb76bdda53a42 426 Gene3D G3DSA:3.30.830.10 230 421 4.5E-29 T 29-03-2018 CB4_RS08505 47926611649c1e1c5e2f7518b75307d9 247 Gene3D G3DSA:3.60.40.10 1 240 5.9E-47 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS08505 47926611649c1e1c5e2f7518b75307d9 247 SMART SM00331 7 241 7.3E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS08505 47926611649c1e1c5e2f7518b75307d9 247 Pfam PF13672 Protein phosphatase 2C 13 211 1.6E-23 T 29-03-2018 CB4_RS08505 47926611649c1e1c5e2f7518b75307d9 247 SUPERFAMILY SSF81606 2 240 7.06E-68 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS08505 47926611649c1e1c5e2f7518b75307d9 247 SMART SM00332 1 239 4.5E-21 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS15115 1b4d1f5447d035fa10248b9c45b07463 271 Gene3D G3DSA:3.20.20.70 8 263 1.8E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS15115 1b4d1f5447d035fa10248b9c45b07463 271 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 69 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CB4_RS15115 1b4d1f5447d035fa10248b9c45b07463 271 Pfam PF00218 Indole-3-glycerol phosphate synthase 2 256 2.9E-85 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CB4_RS15115 1b4d1f5447d035fa10248b9c45b07463 271 SUPERFAMILY SSF51366 9 260 8.71E-81 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CB4_RS15115 1b4d1f5447d035fa10248b9c45b07463 271 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 260 32.334 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CB4_RS12640 f876a7821c37f5888c15dd0eabb99062 477 PIRSF PIRSF005690 4 477 1.8E-149 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS12640 f876a7821c37f5888c15dd0eabb99062 477 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 19 464 7.6E-156 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS17990 1e8808499e46c673b7d7a0d5763b1083 196 Gene3D G3DSA:3.40.190.10 4 75 1.5E-6 T 29-03-2018 CB4_RS17990 1e8808499e46c673b7d7a0d5763b1083 196 Pfam PF03466 LysR substrate binding domain 52 184 7.6E-8 T 29-03-2018 IPR005119 LysR, substrate-binding CB4_RS17990 1e8808499e46c673b7d7a0d5763b1083 196 Gene3D G3DSA:3.40.190.10 76 130 1.5E-4 T 29-03-2018 CB4_RS17990 1e8808499e46c673b7d7a0d5763b1083 196 SUPERFAMILY SSF53850 9 185 2.53E-13 T 29-03-2018 CB4_RS13250 98231c65b47a7f24f331435126a9c67c 55 Pfam PF12788 YmaF family 5 44 1.2E-8 T 29-03-2018 IPR024307 YmaF CB4_RS04140 98c63678fbc7e835a447d3d2533ebbb9 456 SUPERFAMILY SSF55103 217 455 2.45E-63 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CB4_RS04140 98c63678fbc7e835a447d3d2533ebbb9 456 Gene3D G3DSA:3.30.43.10 1 92 9.2E-28 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CB4_RS04140 98c63678fbc7e835a447d3d2533ebbb9 456 SUPERFAMILY SSF56176 2 214 9.81E-70 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CB4_RS04140 98c63678fbc7e835a447d3d2533ebbb9 456 Pfam PF02913 FAD linked oxidases, C-terminal domain 213 453 5.0E-55 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CB4_RS04140 98c63678fbc7e835a447d3d2533ebbb9 456 Pfam PF01565 FAD binding domain 40 177 6.5E-42 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CB4_RS04140 98c63678fbc7e835a447d3d2533ebbb9 456 Gene3D G3DSA:3.30.465.10 93 236 1.3E-43 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CB4_RS04140 98c63678fbc7e835a447d3d2533ebbb9 456 Gene3D G3DSA:1.10.45.10 415 453 5.1E-14 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CB4_RS12590 96030a1cf3b32e3e4faf2c1f844f3ef8 283 SUPERFAMILY SSF51735 1 280 1.51E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS12590 96030a1cf3b32e3e4faf2c1f844f3ef8 283 Gene3D G3DSA:3.90.25.10 164 282 3.4E-10 T 29-03-2018 CB4_RS12590 96030a1cf3b32e3e4faf2c1f844f3ef8 283 Gene3D G3DSA:3.40.50.720 1 158 2.3E-16 T 29-03-2018 CB4_RS12590 96030a1cf3b32e3e4faf2c1f844f3ef8 283 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 214 1.4E-20 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CB4_RS07495 bbbc341099867df56649b71e7d7fa0e0 194 Gene3D G3DSA:3.40.50.150 1 192 3.3E-31 T 29-03-2018 CB4_RS07495 bbbc341099867df56649b71e7d7fa0e0 194 SUPERFAMILY SSF53335 33 179 3.04E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS07495 bbbc341099867df56649b71e7d7fa0e0 194 Pfam PF13649 Methyltransferase domain 44 134 7.5E-23 T 29-03-2018 CB4_RS05865 59c46d32211634e60e3ab2542732ba1e 96 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS05865 59c46d32211634e60e3ab2542732ba1e 96 Gene3D G3DSA:2.40.50.100 28 92 7.6E-29 T 29-03-2018 CB4_RS05865 59c46d32211634e60e3ab2542732ba1e 96 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 26.989 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05865 59c46d32211634e60e3ab2542732ba1e 96 PRINTS PR00063 Ribosomal protein L27 signature 37 61 1.3E-38 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05865 59c46d32211634e60e3ab2542732ba1e 96 PRINTS PR00063 Ribosomal protein L27 signature 62 86 1.3E-38 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05865 59c46d32211634e60e3ab2542732ba1e 96 PRINTS PR00063 Ribosomal protein L27 signature 12 36 1.3E-38 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05865 59c46d32211634e60e3ab2542732ba1e 96 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 1.0E-14 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05865 59c46d32211634e60e3ab2542732ba1e 96 SUPERFAMILY SSF110324 10 90 2.89E-32 T 29-03-2018 CB4_RS05865 59c46d32211634e60e3ab2542732ba1e 96 Pfam PF01016 Ribosomal L27 protein 10 87 6.1E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS05865 59c46d32211634e60e3ab2542732ba1e 96 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 88 3.8E-40 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00550 cb673220f16c730fdffd6ae03db0d122 230 Pfam PF00557 Metallopeptidase family M24 12 176 2.3E-18 T 29-03-2018 IPR000994 Peptidase M24 CB4_RS00550 cb673220f16c730fdffd6ae03db0d122 230 SUPERFAMILY SSF55920 13 197 9.16E-22 T 29-03-2018 IPR000994 Peptidase M24 CB4_RS00550 cb673220f16c730fdffd6ae03db0d122 230 Gene3D G3DSA:3.90.230.10 7 202 5.4E-20 T 29-03-2018 CB4_RS13890 4d1bcc64378150c16db91bfe59dab7c8 227 Pfam PF00929 Exonuclease 17 185 6.6E-15 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS13890 4d1bcc64378150c16db91bfe59dab7c8 227 Gene3D G3DSA:3.30.420.10 1 197 7.1E-32 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS13890 4d1bcc64378150c16db91bfe59dab7c8 227 SUPERFAMILY SSF53098 11 192 2.39E-32 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS13890 4d1bcc64378150c16db91bfe59dab7c8 227 SMART SM00479 15 195 1.9E-18 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS19295 c53cc05e006ad7c714657c35a0b939a7 124 Pfam PF07238 PilZ domain 34 109 2.0E-6 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CB4_RS19295 c53cc05e006ad7c714657c35a0b939a7 124 Gene3D G3DSA:2.40.10.220 20 124 7.6E-12 T 29-03-2018 CB4_RS19295 c53cc05e006ad7c714657c35a0b939a7 124 SUPERFAMILY SSF141371 32 106 5.89E-6 T 29-03-2018 CB4_RS01975 6eca7dd9b84dba66262af0f14f6e2881 212 SUPERFAMILY SSF53163 16 203 1.16E-52 T 29-03-2018 IPR023430 Peptidase HybD-like domain CB4_RS01975 6eca7dd9b84dba66262af0f14f6e2881 212 Pfam PF06866 Protein of unknown function (DUF1256) 20 181 1.5E-62 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 CB4_RS01975 6eca7dd9b84dba66262af0f14f6e2881 212 Gene3D G3DSA:3.40.50.1450 13 160 3.8E-36 T 29-03-2018 IPR023430 Peptidase HybD-like domain CB4_RS01975 6eca7dd9b84dba66262af0f14f6e2881 212 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 45 183 2.8E-66 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 CB4_RS19905 a6dc61426ba11496f39144aebdec0d39 391 Pfam PF07690 Major Facilitator Superfamily 10 321 3.6E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS19905 a6dc61426ba11496f39144aebdec0d39 391 SUPERFAMILY SSF103473 4 377 4.58E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS19905 a6dc61426ba11496f39144aebdec0d39 391 Gene3D G3DSA:1.20.1250.20 2 189 2.1E-24 T 29-03-2018 CB4_RS19905 a6dc61426ba11496f39144aebdec0d39 391 Gene3D G3DSA:1.20.1250.20 191 382 1.2E-21 T 29-03-2018 CB4_RS20330 b7c992978ee08abd0306ee2b28e68f12 292 Gene3D G3DSA:1.10.3470.10 1 280 3.2E-54 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS20330 b7c992978ee08abd0306ee2b28e68f12 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 276 6.1E-44 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 Gene3D G3DSA:3.40.50.40 205 319 2.6E-22 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 SMART SM00870 3 316 5.7E-103 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 Gene3D G3DSA:3.40.50.1170 1 204 5.5E-48 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 PIRSF PIRSF001220 1 319 1.8E-88 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 SUPERFAMILY SSF53774 1 312 1.44E-88 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 PRINTS PR00139 Asparaginase/glutaminase family signature 80 98 2.0E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 2.0E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 PRINTS PR00139 Asparaginase/glutaminase family signature 253 271 2.0E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 PIRSF PIRSF500176 1 318 5.7E-88 T 29-03-2018 CB4_RS15290 a9d14d107b58173154a4eaa1ebd8f53d 319 Pfam PF00710 Asparaginase, N-terminal 3 193 1.9E-53 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CB4_RS19330 89f671da6d9995a34e31c8937491def7 448 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 411 1.7E-74 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CB4_RS19330 89f671da6d9995a34e31c8937491def7 448 Pfam PF01554 MatE 23 184 6.6E-34 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CB4_RS19330 89f671da6d9995a34e31c8937491def7 448 Pfam PF01554 MatE 243 403 3.5E-33 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CB4_RS19330 89f671da6d9995a34e31c8937491def7 448 PIRSF PIRSF006603 1 448 1.6E-129 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CB4_RS10745 f46323194fdac93c155d4b10a1cd8895 201 Pfam PF00694 Aconitase C-terminal domain 1 123 3.5E-37 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CB4_RS10745 f46323194fdac93c155d4b10a1cd8895 201 SUPERFAMILY SSF52016 1 193 8.04E-62 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CB4_RS10745 f46323194fdac93c155d4b10a1cd8895 201 Gene3D G3DSA:3.20.19.10 1 174 1.9E-48 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CB4_RS10745 f46323194fdac93c155d4b10a1cd8895 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 197 43.345 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CB4_RS10745 f46323194fdac93c155d4b10a1cd8895 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 186 8.4E-90 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CB4_RS10910 e01241ed5c50f6827eb35b1032f1a889 415 Pfam PF04143 Sulphur transport 6 163 9.3E-30 T 29-03-2018 IPR007272 Sulphur transport domain CB4_RS10910 e01241ed5c50f6827eb35b1032f1a889 415 Pfam PF04143 Sulphur transport 239 399 5.4E-26 T 29-03-2018 IPR007272 Sulphur transport domain CB4_RS17235 df2c23f2e6edebf48ef40e7796a2f416 201 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 196 3.2E-54 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CB4_RS17235 df2c23f2e6edebf48ef40e7796a2f416 201 PRINTS PR00991 6-phosphofructo-2-kinase family signature 9 31 5.7E-5 T 29-03-2018 IPR003094 Fructose-2,6-bisphosphatase GO:0003824|GO:0005524|GO:0006003 KEGG: 00051+2.7.1.105+3.1.3.46|KEGG: 00500+2.7.1.10|Reactome: R-HSA-70171 CB4_RS17235 df2c23f2e6edebf48ef40e7796a2f416 201 PRINTS PR00991 6-phosphofructo-2-kinase family signature 90 106 5.7E-5 T 29-03-2018 IPR003094 Fructose-2,6-bisphosphatase GO:0003824|GO:0005524|GO:0006003 KEGG: 00051+2.7.1.105+3.1.3.46|KEGG: 00500+2.7.1.10|Reactome: R-HSA-70171 CB4_RS17235 df2c23f2e6edebf48ef40e7796a2f416 201 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 11 20 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CB4_RS17235 df2c23f2e6edebf48ef40e7796a2f416 201 SUPERFAMILY SSF53254 7 200 2.22E-53 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CB4_RS17235 df2c23f2e6edebf48ef40e7796a2f416 201 SMART SM00855 8 158 4.4E-25 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CB4_RS17235 df2c23f2e6edebf48ef40e7796a2f416 201 PIRSF PIRSF000709 1 164 3.9E-11 T 29-03-2018 CB4_RS17235 df2c23f2e6edebf48ef40e7796a2f416 201 Gene3D G3DSA:3.40.50.1240 2 201 1.3E-52 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CB4_RS11615 462921e3d004c5e5d761eb545952ddf6 96 Pfam PF16778 Phage tail assembly chaperone protein 39 96 1.3E-16 T 29-03-2018 IPR031893 Phage tail assembly chaperone protein CB4_RS04045 66d9608d83d9c56422ac31fc85bb452b 303 SUPERFAMILY SSF88713 86 281 2.09E-28 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS04045 66d9608d83d9c56422ac31fc85bb452b 303 Gene3D G3DSA:3.20.20.370 22 298 2.0E-37 T 29-03-2018 CB4_RS04045 66d9608d83d9c56422ac31fc85bb452b 303 Pfam PF01522 Polysaccharide deacetylase 124 262 4.8E-19 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS19610 1ec5762fedf075331190b5843fff0520 482 Pfam PF13148 Protein of unknown function (DUF3987) 68 136 4.7E-14 T 29-03-2018 IPR025048 Protein of unknown function DUF3987) CB4_RS19610 1ec5762fedf075331190b5843fff0520 482 Pfam PF13148 Protein of unknown function (DUF3987) 136 387 2.8E-61 T 29-03-2018 IPR025048 Protein of unknown function DUF3987) CB4_RS15745 8dc06db5c59a57d498eee9598385fcb8 446 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CB4_RS15745 8dc06db5c59a57d498eee9598385fcb8 446 Pfam PF00324 Amino acid permease 16 421 3.6E-83 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CB4_RS15745 8dc06db5c59a57d498eee9598385fcb8 446 PIRSF PIRSF006060 1 446 9.4E-67 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS08820 a97ff967e4ab497b68abd9d33e0c8bef 300 Pfam PF01695 IstB-like ATP binding protein 114 246 9.6E-20 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CB4_RS08820 a97ff967e4ab497b68abd9d33e0c8bef 300 Gene3D G3DSA:3.40.50.300 100 281 4.1E-22 T 29-03-2018 CB4_RS08820 a97ff967e4ab497b68abd9d33e0c8bef 300 SUPERFAMILY SSF52540 104 248 4.18E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS02525 7f432bdf91fb1032e08c4e1d7384d08f 188 Gene3D G3DSA:3.40.1130.10 1 188 6.9E-44 T 29-03-2018 CB4_RS02525 7f432bdf91fb1032e08c4e1d7384d08f 188 SMART SM00563 34 146 1.3E-34 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CB4_RS02525 7f432bdf91fb1032e08c4e1d7384d08f 188 SUPERFAMILY SSF69593 12 184 1.83E-41 T 29-03-2018 CB4_RS02525 7f432bdf91fb1032e08c4e1d7384d08f 188 Pfam PF01553 Acyltransferase 19 143 2.4E-26 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CB4_RS03895 575d2695b0b38f37228f33468f73fcad 264 SUPERFAMILY SSF53474 28 259 4.22E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS03895 575d2695b0b38f37228f33468f73fcad 264 Pfam PF12146 Serine aminopeptidase, S33 33 243 4.0E-20 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CB4_RS03895 575d2695b0b38f37228f33468f73fcad 264 PIRSF PIRSF017388 15 261 7.5E-75 T 29-03-2018 IPR012354 Esterase/lipase GO:0052689 CB4_RS03895 575d2695b0b38f37228f33468f73fcad 264 Gene3D G3DSA:3.40.50.1820 17 261 3.5E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS04300 0797a601d50fb75e4a943eea72e475b3 235 Pfam PF01955 Adenosylcobinamide amidohydrolase 34 225 3.9E-54 T 29-03-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ CB4_RS18055 e0e6fb4be1c8555dcd4150d20c456ef2 209 Gene3D G3DSA:3.90.850.10 1 208 2.6E-55 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS18055 e0e6fb4be1c8555dcd4150d20c456ef2 209 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 6 195 4.6E-37 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS18055 e0e6fb4be1c8555dcd4150d20c456ef2 209 SUPERFAMILY SSF56529 5 202 7.72E-51 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS05495 b78ebcd47b0414ab96e742e05e7ce24d 457 Pfam PF00939 Sodium:sulfate symporter transmembrane region 2 457 1.6E-159 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CB4_RS05495 b78ebcd47b0414ab96e742e05e7ce24d 457 PIRSF PIRSF002457 1 457 1.5E-153 T 29-03-2018 IPR030676 Citrate carrier CitT-related CB4_RS05495 b78ebcd47b0414ab96e742e05e7ce24d 457 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 14 451 1.1E-129 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CB4_RS15600 e9169b9a51b2a30b05d7dccf0a4e39c0 165 Gene3D G3DSA:1.10.260.40 1 164 8.3E-8 T 29-03-2018 CB4_RS15600 e9169b9a51b2a30b05d7dccf0a4e39c0 165 SUPERFAMILY SSF47413 3 51 9.92E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS10325 7e3e38221c0fabae26b7afc92c98f3d8 150 Pfam PF13115 YtkA-like 50 132 1.8E-12 T 29-03-2018 IPR032693 YtkA-like domain CB4_RS10325 7e3e38221c0fabae26b7afc92c98f3d8 150 Gene3D G3DSA:2.60.40.10 45 150 3.2E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS17080 53c654c689382ea326ea322fec2b2247 384 Gene3D G3DSA:3.90.1150.10 241 384 1.0E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS17080 53c654c689382ea326ea322fec2b2247 384 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 211 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CB4_RS17080 53c654c689382ea326ea322fec2b2247 384 PIRSF PIRSF005572 1 382 2.3E-122 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CB4_RS17080 53c654c689382ea326ea322fec2b2247 384 Gene3D G3DSA:3.40.640.10 10 240 7.1E-55 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS17080 53c654c689382ea326ea322fec2b2247 384 SUPERFAMILY SSF53383 1 375 1.32E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS17080 53c654c689382ea326ea322fec2b2247 384 Pfam PF00266 Aminotransferase class-V 2 366 2.4E-78 T 29-03-2018 IPR000192 Aminotransferase class V domain CB4_RS15450 91c18b6897b4773197eb0e31034c4a37 1189 Gene3D G3DSA:1.20.1480.30 830 966 0.0041 T 29-03-2018 CB4_RS15450 91c18b6897b4773197eb0e31034c4a37 1189 Gene3D G3DSA:1.20.120.20 11 557 0.0021 T 29-03-2018 CB4_RS15450 91c18b6897b4773197eb0e31034c4a37 1189 Gene3D G3DSA:1.20.120.20 972 1162 0.24 T 29-03-2018 CB4_RS15450 91c18b6897b4773197eb0e31034c4a37 1189 Gene3D G3DSA:1.10.490.30 728 829 6.8E-6 T 29-03-2018 CB4_RS05390 2a71f686fd3c14cb66a99b94196ddc41 186 Pfam PF02674 Colicin V production protein 4 161 7.2E-30 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 SMART SM00344 1 105 3.3E-41 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 Gene3D G3DSA:1.10.10.10 1 50 7.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.4E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.4E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.4E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 Pfam PF01037 Lrp/AsnC ligand binding domain 71 114 4.4E-9 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 Gene3D G3DSA:3.30.70.920 51 137 3.4E-14 T 29-03-2018 CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 SUPERFAMILY SSF54909 65 130 1.18E-10 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 SUPERFAMILY SSF46785 1 60 2.19E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CB4_RS19900 c89f439c2e6b73425a0183cfe2b61178 146 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 4.2E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS08325 c3565e45b5bea212eddea7fa27ebd7a3 92 Gene3D G3DSA:2.30.30.240 1 81 5.7E-18 T 29-03-2018 CB4_RS08325 c3565e45b5bea212eddea7fa27ebd7a3 92 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 77 2.8E-25 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH CB4_RS08325 c3565e45b5bea212eddea7fa27ebd7a3 92 Pfam PF05239 PRC-barrel domain 2 77 1.4E-13 T 29-03-2018 IPR027275 PRC-barrel domain CB4_RS08325 c3565e45b5bea212eddea7fa27ebd7a3 92 SUPERFAMILY SSF50346 1 76 4.71E-13 T 29-03-2018 IPR011033 PRC-barrel-like CB4_RS12930 38c91fff914f5443a9767899962d8687 466 Gene3D G3DSA:1.10.287.470 146 214 1.3E-7 T 29-03-2018 CB4_RS12930 38c91fff914f5443a9767899962d8687 466 SUPERFAMILY SSF111369 64 167 1.57E-12 T 29-03-2018 CB4_RS12930 38c91fff914f5443a9767899962d8687 466 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 221 435 1.0E-47 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CB4_RS12930 38c91fff914f5443a9767899962d8687 466 SUPERFAMILY SSF111369 193 359 8.5E-15 T 29-03-2018 CB4_RS12930 38c91fff914f5443a9767899962d8687 466 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 157 355 5.0E-23 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CB4_RS12930 38c91fff914f5443a9767899962d8687 466 Pfam PF13533 Biotin-lipoyl like 74 121 5.5E-10 T 29-03-2018 CB4_RS12930 38c91fff914f5443a9767899962d8687 466 Gene3D G3DSA:2.40.50.100 72 143 6.2E-15 T 29-03-2018 CB4_RS12930 38c91fff914f5443a9767899962d8687 466 Gene3D G3DSA:1.20.1600.10 220 360 1.8E-15 T 29-03-2018 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 PRINTS PR00449 Transforming protein P21 ras signature 324 337 8.8E-5 T 29-03-2018 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 PRINTS PR00449 Transforming protein P21 ras signature 220 241 8.8E-5 T 29-03-2018 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 PRINTS PR00449 Transforming protein P21 ras signature 260 282 8.8E-5 T 29-03-2018 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 Gene3D G3DSA:1.20.120.430 285 457 4.2E-28 T 29-03-2018 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 223 369 1.4E-26 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 Pfam PF01926 50S ribosome-binding GTPase 223 334 2.0E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 Gene3D G3DSA:1.20.120.430 125 284 4.1E-31 T 29-03-2018 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 10 457 5.2E-129 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 Gene3D G3DSA:3.30.1360.120 1 124 2.7E-45 T 29-03-2018 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 SUPERFAMILY SSF52540 200 373 4.25E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 SUPERFAMILY SSF52540 77 166 4.25E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 123 7.0E-40 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 Pfam PF12631 MnmE helical domain 126 454 2.9E-60 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 457 34.475 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 SUPERFAMILY SSF116878 124 223 1.57E-50 T 29-03-2018 CB4_RS01935 c566d08275fa910f0f95b5652ab6eff7 457 SUPERFAMILY SSF116878 382 457 1.57E-50 T 29-03-2018 CB4_RS16635 d0e9572fa6122197f0d040340f0fe10a 208 Pfam PF01464 Transglycosylase SLT domain 93 200 2.0E-27 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CB4_RS16635 d0e9572fa6122197f0d040340f0fe10a 208 SUPERFAMILY SSF53955 73 207 1.3E-44 T 29-03-2018 IPR023346 Lysozyme-like domain CB4_RS16635 d0e9572fa6122197f0d040340f0fe10a 208 Gene3D G3DSA:1.10.530.10 24 208 4.0E-47 T 29-03-2018 CB4_RS00520 239b5dc75cd72314f101971c43f4be08 507 SUPERFAMILY SSF48557 1 497 2.04E-196 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CB4_RS00520 239b5dc75cd72314f101971c43f4be08 507 Gene3D G3DSA:1.20.200.10 197 506 1.8E-125 T 29-03-2018 CB4_RS00520 239b5dc75cd72314f101971c43f4be08 507 Pfam PF00221 Aromatic amino acid lyase 9 466 6.2E-197 T 29-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CB4_RS00520 239b5dc75cd72314f101971c43f4be08 507 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 1 500 45.753 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00520 239b5dc75cd72314f101971c43f4be08 507 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 137 153 - T 29-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CB4_RS00520 239b5dc75cd72314f101971c43f4be08 507 Gene3D G3DSA:1.10.275.10 1 195 1.0E-75 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CB4_RS00520 239b5dc75cd72314f101971c43f4be08 507 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 499 1.5E-219 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CB4_RS00980 079fdcd0fd2a9e6ba16a3968cdcaa29d 348 SUPERFAMILY SSF109604 124 285 4.28E-18 T 29-03-2018 CB4_RS00980 079fdcd0fd2a9e6ba16a3968cdcaa29d 348 Gene3D G3DSA:1.10.3210.10 45 288 1.8E-29 T 29-03-2018 CB4_RS00980 079fdcd0fd2a9e6ba16a3968cdcaa29d 348 Pfam PF13487 HD domain 180 240 3.4E-18 T 29-03-2018 CB4_RS12965 c20b122a88f4cf8fac4ff66d2a68380b 296 SUPERFAMILY SSF103481 34 137 3.79E-16 T 29-03-2018 CB4_RS12965 c20b122a88f4cf8fac4ff66d2a68380b 296 Pfam PF00892 EamA-like transporter family 7 134 5.0E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS12965 c20b122a88f4cf8fac4ff66d2a68380b 296 Pfam PF00892 EamA-like transporter family 148 280 2.5E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS12965 c20b122a88f4cf8fac4ff66d2a68380b 296 SUPERFAMILY SSF103481 182 280 1.31E-11 T 29-03-2018 CB4_RS02245 eb117c4b5dd0c86f9f1da0e4622744d3 883 SUPERFAMILY SSF82171 537 769 2.71E-5 T 29-03-2018 CB4_RS02245 eb117c4b5dd0c86f9f1da0e4622744d3 883 Gene3D G3DSA:2.130.10.10 213 837 5.1E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS02245 eb117c4b5dd0c86f9f1da0e4622744d3 883 Pfam PF00395 S-layer homology domain 105 138 0.0016 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02245 eb117c4b5dd0c86f9f1da0e4622744d3 883 Pfam PF00395 S-layer homology domain 163 208 1.9E-10 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02245 eb117c4b5dd0c86f9f1da0e4622744d3 883 Pfam PF00395 S-layer homology domain 37 79 6.7E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS11180 0e318f674971f5cd2fbe542cd4045175 211 Gene3D G3DSA:3.40.50.620 47 180 1.3E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS11180 0e318f674971f5cd2fbe542cd4045175 211 Pfam PF02698 DUF218 domain 58 203 2.5E-26 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CB4_RS11110 6bdde80a0ea378b111dc582520c3d193 131 Pfam PF13686 DsrE/DsrF/DrsH-like family 61 129 1.2E-21 T 29-03-2018 IPR032836 DsrE2-like family CB4_RS11110 6bdde80a0ea378b111dc582520c3d193 131 Pfam PF13686 DsrE/DsrF/DrsH-like family 3 55 2.7E-11 T 29-03-2018 IPR032836 DsrE2-like family CB4_RS11110 6bdde80a0ea378b111dc582520c3d193 131 SUPERFAMILY SSF75169 3 131 6.73E-23 T 29-03-2018 IPR027396 DsrEFH-like CB4_RS11110 6bdde80a0ea378b111dc582520c3d193 131 Gene3D G3DSA:3.40.1260.10 1 130 4.0E-39 T 29-03-2018 CB4_RS10395 36ac35690c03de995514b8b52058314b 186 Gene3D G3DSA:3.10.450.50 35 172 3.2E-15 T 29-03-2018 CB4_RS10395 36ac35690c03de995514b8b52058314b 186 SUPERFAMILY SSF103642 152 171 4.58E-7 T 29-03-2018 CB4_RS10395 36ac35690c03de995514b8b52058314b 186 Pfam PF02810 SEC-C motif 153 171 2.3E-9 T 29-03-2018 IPR004027 SEC-C motif CB4_RS08030 2558a13a9eaaa46ada91f3f79e6c16b0 281 SUPERFAMILY SSF89550 1 81 1.2E-48 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CB4_RS08030 2558a13a9eaaa46ada91f3f79e6c16b0 281 SUPERFAMILY SSF89550 165 248 1.2E-48 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CB4_RS08030 2558a13a9eaaa46ada91f3f79e6c16b0 281 Gene3D G3DSA:3.20.20.140 1 250 2.2E-49 T 29-03-2018 CB4_RS08030 2558a13a9eaaa46ada91f3f79e6c16b0 281 Pfam PF02811 PHP domain 4 158 3.1E-10 T 29-03-2018 IPR004013 PHP domain GO:0003824 CB4_RS08030 2558a13a9eaaa46ada91f3f79e6c16b0 281 SMART SM00481 3 68 6.7E-23 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CB4_RS02730 3ff48fab28d052e538e157fbb42aaa79 288 TIGRFAM TIGR01230 agmatinase: agmatinase 12 284 2.3E-103 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CB4_RS02730 3ff48fab28d052e538e157fbb42aaa79 288 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CB4_RS02730 3ff48fab28d052e538e157fbb42aaa79 288 SUPERFAMILY SSF52768 10 287 4.5E-83 T 29-03-2018 CB4_RS02730 3ff48fab28d052e538e157fbb42aaa79 288 Pfam PF00491 Arginase family 24 283 1.5E-75 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS02730 3ff48fab28d052e538e157fbb42aaa79 288 Gene3D G3DSA:3.40.800.10 6 288 9.3E-80 T 29-03-2018 CB4_RS02730 3ff48fab28d052e538e157fbb42aaa79 288 PIRSF PIRSF036979 2 288 5.3E-94 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS04295 23b1ba47c532069baf44726e0bea015c 289 Gene3D G3DSA:3.30.230.10 18 145 5.9E-9 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS04295 23b1ba47c532069baf44726e0bea015c 289 PIRSF PIRSF033887 1 279 1.0E-79 T 29-03-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 CB4_RS04295 23b1ba47c532069baf44726e0bea015c 289 SUPERFAMILY SSF54211 2 154 2.35E-15 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS00865 bea817acfad8fa6d44114288f8ee0ef0 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 3.8E-26 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00865 bea817acfad8fa6d44114288f8ee0ef0 61 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 29-03-2018 IPR018038 Ribosomal protein L30, conserved site CB4_RS00865 bea817acfad8fa6d44114288f8ee0ef0 61 PIRSF PIRSF002211 1 60 2.3E-28 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00865 bea817acfad8fa6d44114288f8ee0ef0 61 SUPERFAMILY SSF55129 1 59 1.44E-20 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CB4_RS00865 bea817acfad8fa6d44114288f8ee0ef0 61 Pfam PF00327 Ribosomal protein L30p/L7e 5 54 8.7E-20 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CB4_RS00865 bea817acfad8fa6d44114288f8ee0ef0 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.159 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00865 bea817acfad8fa6d44114288f8ee0ef0 61 Gene3D G3DSA:3.30.1390.20 4 58 3.4E-24 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CB4_RS08040 02e788f6bda8e23df62201052662125c 184 SUPERFAMILY SSF101307 12 163 1.31E-45 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CB4_RS08040 02e788f6bda8e23df62201052662125c 184 PIRSF PIRSF019587 5 169 1.3E-58 T 29-03-2018 IPR026038 Putative phosphatidylglycerophosphatase CB4_RS08040 02e788f6bda8e23df62201052662125c 184 Gene3D G3DSA:1.10.3760.10 1 178 2.7E-56 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CB4_RS08040 02e788f6bda8e23df62201052662125c 184 Pfam PF04608 Phosphatidylglycerophosphatase A 20 158 1.6E-17 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CB4_RS10605 562771f2afefb78e9ea535c9fcace2dd 385 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 377 1.3E-125 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CB4_RS10605 562771f2afefb78e9ea535c9fcace2dd 385 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 175 203 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CB4_RS10605 562771f2afefb78e9ea535c9fcace2dd 385 Gene3D G3DSA:1.20.1090.10 187 385 2.5E-70 T 29-03-2018 CB4_RS10605 562771f2afefb78e9ea535c9fcace2dd 385 Gene3D G3DSA:3.40.50.1970 11 184 1.6E-47 T 29-03-2018 CB4_RS10605 562771f2afefb78e9ea535c9fcace2dd 385 SUPERFAMILY SSF56796 4 385 2.09E-135 T 29-03-2018 CB4_RS03305 e50f2d7e112c6904ee39b068aa5f1078 539 Pfam PF00395 S-layer homology domain 33 73 2.4E-13 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS03305 e50f2d7e112c6904ee39b068aa5f1078 539 Pfam PF00395 S-layer homology domain 89 132 1.2E-13 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS03305 e50f2d7e112c6904ee39b068aa5f1078 539 Pfam PF00395 S-layer homology domain 148 190 7.9E-13 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 223 4.1E-28 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 SMART SM01232 134 226 2.3E-43 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 2.7E-104 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 SUPERFAMILY SSF46946 135 227 4.58E-28 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 Gene3D G3DSA:3.20.190.10 2 131 1.9E-40 T 29-03-2018 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 SMART SM00898 2 118 8.0E-48 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 SUPERFAMILY SSF57716 222 274 2.0E-17 T 29-03-2018 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 Pfam PF06827 Zinc finger found in FPG and IleRS 246 275 3.5E-10 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 42.807 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 SUPERFAMILY SSF81624 2 139 2.09E-41 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 2.9E-34 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CB4_RS18360 37cb5e189d0a81dc67fd75af3b03da4e 276 Gene3D G3DSA:1.10.8.50 135 276 5.9E-49 T 29-03-2018 CB4_RS12790 4e4c34d483d17ab6f58cea470d8ca19d 311 SUPERFAMILY SSF160240 220 292 5.1E-10 T 29-03-2018 CB4_RS12790 4e4c34d483d17ab6f58cea470d8ca19d 311 Pfam PF01545 Cation efflux family 25 214 7.3E-45 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CB4_RS12790 4e4c34d483d17ab6f58cea470d8ca19d 311 Gene3D G3DSA:1.20.1510.10 20 214 5.9E-48 T 29-03-2018 CB4_RS12790 4e4c34d483d17ab6f58cea470d8ca19d 311 Gene3D G3DSA:3.30.70.1350 216 298 1.6E-11 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CB4_RS12790 4e4c34d483d17ab6f58cea470d8ca19d 311 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 296 1.8E-73 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CB4_RS12790 4e4c34d483d17ab6f58cea470d8ca19d 311 SUPERFAMILY SSF161111 17 215 3.53E-51 T 29-03-2018 CB4_RS02570 3e2273fb6b5ead2cd1bc0d1b9cb3cf7b 269 Gene3D G3DSA:3.40.50.300 3 269 2.0E-52 T 29-03-2018 CB4_RS02570 3e2273fb6b5ead2cd1bc0d1b9cb3cf7b 269 Pfam PF13614 AAA domain 4 188 3.8E-49 T 29-03-2018 IPR025669 AAA domain CB4_RS02570 3e2273fb6b5ead2cd1bc0d1b9cb3cf7b 269 SUPERFAMILY SSF52540 4 263 1.9E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07455 c322ffc0cef10edcbd32dd68471ab8b8 253 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 50 223 3.5E-36 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS07455 c322ffc0cef10edcbd32dd68471ab8b8 253 SMART SM00479 55 223 2.4E-49 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS07455 c322ffc0cef10edcbd32dd68471ab8b8 253 Gene3D G3DSA:3.30.420.10 44 195 1.9E-39 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS07455 c322ffc0cef10edcbd32dd68471ab8b8 253 Gene3D G3DSA:1.20.5.140 200 226 1.6E-9 T 29-03-2018 CB4_RS07455 c322ffc0cef10edcbd32dd68471ab8b8 253 SUPERFAMILY SSF53098 54 230 2.37E-58 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS07455 c322ffc0cef10edcbd32dd68471ab8b8 253 Pfam PF00929 Exonuclease 57 214 2.6E-34 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS07310 86c87dfb0d84981c1a055be6981da41c 100 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 100 44.011 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CB4_RS07310 86c87dfb0d84981c1a055be6981da41c 100 Gene3D G3DSA:1.10.3720.10 1 97 7.9E-4 T 29-03-2018 CB4_RS07310 86c87dfb0d84981c1a055be6981da41c 100 Pfam PF02553 Cobalt transport protein component CbiN 6 72 8.7E-30 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CB4_RS06440 992d580ed10f05dcc67c0c713c4b6216 87 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 1 86 2.0E-12 T 29-03-2018 IPR020390 Uncharacterised protein family YqhV CB4_RS06440 992d580ed10f05dcc67c0c713c4b6216 87 Pfam PF10942 Protein of unknown function (DUF2619) 13 81 3.9E-29 T 29-03-2018 IPR020390 Uncharacterised protein family YqhV CB4_RS12290 b156d54719a50dd91f383ac8f47159fe 306 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS12290 b156d54719a50dd91f383ac8f47159fe 306 SUPERFAMILY SSF52540 4 232 2.56E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12290 b156d54719a50dd91f383ac8f47159fe 306 Pfam PF00005 ABC transporter 22 162 6.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS12290 b156d54719a50dd91f383ac8f47159fe 306 Gene3D G3DSA:3.40.50.300 2 265 1.6E-61 T 29-03-2018 CB4_RS12290 b156d54719a50dd91f383ac8f47159fe 306 SMART SM00382 30 210 4.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS00200 ee1edcbd82cefcde4308e10c3689a161 86 SMART SM00899 9 81 2.3E-18 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CB4_RS00200 ee1edcbd82cefcde4308e10c3689a161 86 Pfam PF04023 FeoA domain 10 81 4.8E-17 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CB4_RS00200 ee1edcbd82cefcde4308e10c3689a161 86 Gene3D G3DSA:2.30.30.90 8 86 1.1E-19 T 29-03-2018 CB4_RS00200 ee1edcbd82cefcde4308e10c3689a161 86 SUPERFAMILY SSF50037 12 82 7.1E-19 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CB4_RS17300 f2e81dbe91caf11fb71b107a363d3310 575 Gene3D G3DSA:3.30.300.30 461 573 8.7E-27 T 29-03-2018 CB4_RS17300 f2e81dbe91caf11fb71b107a363d3310 575 Pfam PF13193 AMP-binding enzyme C-terminal domain 474 552 1.7E-23 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS17300 f2e81dbe91caf11fb71b107a363d3310 575 Gene3D G3DSA:2.30.38.10 373 458 1.1E-22 T 29-03-2018 CB4_RS17300 f2e81dbe91caf11fb71b107a363d3310 575 Gene3D G3DSA:3.40.50.980 44 219 7.5E-40 T 29-03-2018 CB4_RS17300 f2e81dbe91caf11fb71b107a363d3310 575 SUPERFAMILY SSF56801 27 565 7.2E-162 T 29-03-2018 CB4_RS17300 f2e81dbe91caf11fb71b107a363d3310 575 ProSitePatterns PS00455 Putative AMP-binding domain signature. 214 225 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS17300 f2e81dbe91caf11fb71b107a363d3310 575 Pfam PF00501 AMP-binding enzyme 62 464 7.7E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS17300 f2e81dbe91caf11fb71b107a363d3310 575 Gene3D G3DSA:3.40.50.980 220 372 4.2E-40 T 29-03-2018 CB4_RS02850 ad3301b0bf21383563992ca1426e5133 168 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 53 163 2.0E-17 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CB4_RS10420 25be8cf416a23f65f7b406d0a0dc28d0 512 SUPERFAMILY SSF56801 6 510 9.81E-167 T 29-03-2018 CB4_RS10420 25be8cf416a23f65f7b406d0a0dc28d0 512 Gene3D G3DSA:3.40.50.980 6 178 3.0E-43 T 29-03-2018 CB4_RS10420 25be8cf416a23f65f7b406d0a0dc28d0 512 Pfam PF00501 AMP-binding enzyme 18 417 1.2E-115 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS10420 25be8cf416a23f65f7b406d0a0dc28d0 512 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 500 9.1E-23 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS10420 25be8cf416a23f65f7b406d0a0dc28d0 512 Gene3D G3DSA:3.40.50.980 179 326 6.9E-50 T 29-03-2018 CB4_RS10420 25be8cf416a23f65f7b406d0a0dc28d0 512 Gene3D G3DSA:3.30.300.30 411 512 1.3E-32 T 29-03-2018 CB4_RS10420 25be8cf416a23f65f7b406d0a0dc28d0 512 Gene3D G3DSA:2.30.38.10 327 410 9.0E-27 T 29-03-2018 CB4_RS10420 25be8cf416a23f65f7b406d0a0dc28d0 512 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS18655 1873355d561dba509f7e2e6e60f481cf 104 Pfam PF06865 Protein of unknown function (DUF1255) 11 101 4.7E-36 T 29-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase CB4_RS18655 1873355d561dba509f7e2e6e60f481cf 104 SUPERFAMILY SSF51182 11 102 3.56E-32 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS18655 1873355d561dba509f7e2e6e60f481cf 104 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 10 102 26.511 T 29-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase CB4_RS18655 1873355d561dba509f7e2e6e60f481cf 104 Gene3D G3DSA:2.60.120.10 2 101 6.4E-39 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 Pfam PF00672 HAMP domain 203 252 2.2E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 SUPERFAMILY SSF58104 228 258 3.79E-77 T 29-03-2018 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 SUPERFAMILY SSF58104 291 559 3.79E-77 T 29-03-2018 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 SMART SM00304 203 256 2.3E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 SMART SM00283 285 560 4.6E-92 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 Gene3D G3DSA:1.20.120.230 501 558 0.0032 T 29-03-2018 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 330 513 1.7E-48 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 26 3.0E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 383 410 3.0E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 412 441 3.0E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 157 1.0E-12 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 Gene3D G3DSA:1.10.287.950 50 313 1.1E-9 T 29-03-2018 CB4_RS02550 67ecf112c83f5c6c3ab08eb75e964e03 561 Gene3D G3DSA:1.10.287.950 314 500 3.8E-55 T 29-03-2018 CB4_RS10010 4057b578de48518e467f3a6ee7435ca2 467 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 397 1.5E-8 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS10010 4057b578de48518e467f3a6ee7435ca2 467 Gene3D G3DSA:3.90.190.20 316 451 7.2E-24 T 29-03-2018 CB4_RS10010 4057b578de48518e467f3a6ee7435ca2 467 Gene3D G3DSA:3.40.1190.10 86 314 4.7E-43 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS10010 4057b578de48518e467f3a6ee7435ca2 467 SUPERFAMILY SSF53623 103 314 4.19E-44 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS10010 4057b578de48518e467f3a6ee7435ca2 467 Pfam PF08245 Mur ligase middle domain 109 296 7.6E-35 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CB4_RS10010 4057b578de48518e467f3a6ee7435ca2 467 SUPERFAMILY SSF53244 318 441 1.5E-17 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CB4_RS09015 cbcfd243726561f4f1389143942a3307 171 SMART SM00530 48 103 2.2E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS09015 cbcfd243726561f4f1389143942a3307 171 SMART SM00530 117 169 66.0 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS09015 cbcfd243726561f4f1389143942a3307 171 Gene3D G3DSA:1.10.260.40 109 171 5.1E-7 T 29-03-2018 CB4_RS09015 cbcfd243726561f4f1389143942a3307 171 Pfam PF01381 Helix-turn-helix 49 100 2.0E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS09015 cbcfd243726561f4f1389143942a3307 171 SUPERFAMILY SSF47413 113 164 3.44E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS09015 cbcfd243726561f4f1389143942a3307 171 Gene3D G3DSA:1.10.260.40 38 108 6.5E-13 T 29-03-2018 CB4_RS09015 cbcfd243726561f4f1389143942a3307 171 SUPERFAMILY SSF47413 42 108 2.82E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS13260 74f900273d45c50ba2186a87f6beaf8c 574 Gene3D G3DSA:3.40.50.300 316 573 4.7E-77 T 29-03-2018 CB4_RS13260 74f900273d45c50ba2186a87f6beaf8c 574 Pfam PF00664 ABC transporter transmembrane region 16 286 2.6E-48 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS13260 74f900273d45c50ba2186a87f6beaf8c 574 SUPERFAMILY SSF52540 326 567 1.85E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13260 74f900273d45c50ba2186a87f6beaf8c 574 SMART SM00382 357 543 8.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS13260 74f900273d45c50ba2186a87f6beaf8c 574 SUPERFAMILY SSF90123 4 314 1.16E-80 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CB4_RS13260 74f900273d45c50ba2186a87f6beaf8c 574 Pfam PF00005 ABC transporter 348 495 1.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS13260 74f900273d45c50ba2186a87f6beaf8c 574 Gene3D G3DSA:1.20.1560.10 1 315 6.1E-87 T 29-03-2018 CB4_RS13260 74f900273d45c50ba2186a87f6beaf8c 574 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS10995 9073df2e593b5bb445628741ab4ea271 228 Pfam PF04172 LrgB-like family 13 224 5.7E-66 T 29-03-2018 IPR007300 CidB/LrgB family CB4_RS01570 22340e0d7613619c1bdc131b0ea0b287 126 PIRSF PIRSF021439 1 125 1.9E-36 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CB4_RS01570 22340e0d7613619c1bdc131b0ea0b287 126 Pfam PF06156 Initiation control protein YabA 2 120 2.8E-34 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CB4_RS01570 22340e0d7613619c1bdc131b0ea0b287 126 Hamap MF_01159 Initiation-control protein YabA. 1 124 22.934 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CB4_RS08455 c2ea7563f3eee06c91a2266ebb94b613 292 Pfam PF08340 Domain of unknown function (DUF1732) 209 292 1.6E-34 T 29-03-2018 IPR013551 Domain of unknown function DUF1732 CB4_RS08455 c2ea7563f3eee06c91a2266ebb94b613 292 Pfam PF03755 YicC-like family, N-terminal region 2 155 4.3E-43 T 29-03-2018 IPR013527 YicC-like, N-terminal CB4_RS08455 c2ea7563f3eee06c91a2266ebb94b613 292 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 292 1.4E-85 T 29-03-2018 IPR005229 Conserved hypothetical protein CHP00255 CB4_RS14970 21455f893609441afab6234593baed20 285 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 8 268 7.7E-115 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CB4_RS14970 21455f893609441afab6234593baed20 285 Pfam PF02548 Ketopantoate hydroxymethyltransferase 7 263 4.4E-120 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CB4_RS14970 21455f893609441afab6234593baed20 285 Gene3D G3DSA:3.20.20.60 2 268 4.2E-91 T 29-03-2018 CB4_RS14970 21455f893609441afab6234593baed20 285 PIRSF PIRSF000388 1 271 1.9E-119 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CB4_RS14970 21455f893609441afab6234593baed20 285 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 7 268 46.565 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CB4_RS14970 21455f893609441afab6234593baed20 285 SUPERFAMILY SSF51621 7 268 5.1E-113 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CB4_RS06830 9c76e20c3f08b96e029445701cc4c353 550 Gene3D G3DSA:2.40.50.260 300 390 4.9E-5 T 29-03-2018 CB4_RS06830 9c76e20c3f08b96e029445701cc4c353 550 Pfam PF05954 Phage late control gene D protein (GPD) 72 176 1.3E-7 T 29-03-2018 CB4_RS06830 9c76e20c3f08b96e029445701cc4c353 550 Gene3D G3DSA:3.55.50.10 103 193 6.6E-12 T 29-03-2018 CB4_RS06830 9c76e20c3f08b96e029445701cc4c353 550 SUPERFAMILY SSF69279 16 177 3.57E-22 T 29-03-2018 CB4_RS17765 6e8b8919e14df345e9abbc03a884fc93 65 Pfam PF06014 Bacterial protein of unknown function (DUF910) 2 58 1.1E-18 T 29-03-2018 IPR009256 Protein of unknown function DUF910 CB4_RS17765 6e8b8919e14df345e9abbc03a884fc93 65 SUPERFAMILY SSF158379 2 58 4.45E-15 T 29-03-2018 IPR023164 YqgQ-like domain CB4_RS17765 6e8b8919e14df345e9abbc03a884fc93 65 Gene3D G3DSA:1.10.287.760 1 61 1.2E-20 T 29-03-2018 IPR023164 YqgQ-like domain CB4_RS01590 794af2ca3bfb1eacc0bfc20289d4635f 219 Gene3D G3DSA:3.40.50.300 1 213 1.6E-52 T 29-03-2018 CB4_RS01590 794af2ca3bfb1eacc0bfc20289d4635f 219 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 199 1.3E-53 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CB4_RS01590 794af2ca3bfb1eacc0bfc20289d4635f 219 Pfam PF02223 Thymidylate kinase 8 199 2.0E-49 T 29-03-2018 CB4_RS01590 794af2ca3bfb1eacc0bfc20289d4635f 219 Hamap MF_00165 Thymidylate kinase [tmk]. 4 209 30.009 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CB4_RS01590 794af2ca3bfb1eacc0bfc20289d4635f 219 SUPERFAMILY SSF52540 2 205 1.44E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13860 e271e87fbaded60d903ee524cfea3474 369 SMART SM01043 232 366 2.1E-10 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain CB4_RS13860 e271e87fbaded60d903ee524cfea3474 369 Gene3D G3DSA:1.10.10.10 130 264 2.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13860 e271e87fbaded60d903ee524cfea3474 369 SUPERFAMILY SSF48452 302 365 1.1E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS13860 e271e87fbaded60d903ee524cfea3474 369 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 210 5.5E-6 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS13860 e271e87fbaded60d903ee524cfea3474 369 Gene3D G3DSA:3.40.50.2300 1 129 8.7E-30 T 29-03-2018 CB4_RS13860 e271e87fbaded60d903ee524cfea3474 369 SMART SM00448 1 112 1.3E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13860 e271e87fbaded60d903ee524cfea3474 369 Pfam PF03704 Bacterial transcriptional activator domain 252 362 4.5E-13 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain CB4_RS13860 e271e87fbaded60d903ee524cfea3474 369 SUPERFAMILY SSF52172 1 128 7.12E-30 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS13860 e271e87fbaded60d903ee524cfea3474 369 Pfam PF00072 Response regulator receiver domain 4 112 2.4E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13860 e271e87fbaded60d903ee524cfea3474 369 SUPERFAMILY SSF46894 136 212 1.16E-10 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS16930 bbb1077ef2fbf2ec685807b82f032506 216 Pfam PF11167 Protein of unknown function (DUF2953) 134 186 5.9E-10 T 29-03-2018 IPR021338 Protein of unknown function DUF2953 CB4_RS18085 25cc8383922dee53787699d1f656aac8 442 Pfam PF00501 AMP-binding enzyme 78 334 8.9E-12 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS18085 25cc8383922dee53787699d1f656aac8 442 PIRSF PIRSF006444 1 438 7.3E-193 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CB4_RS18085 25cc8383922dee53787699d1f656aac8 442 Gene3D G3DSA:3.40.50.980 81 254 8.0E-15 T 29-03-2018 CB4_RS18085 25cc8383922dee53787699d1f656aac8 442 Gene3D G3DSA:3.30.300.30 325 438 3.2E-7 T 29-03-2018 CB4_RS18085 25cc8383922dee53787699d1f656aac8 442 SUPERFAMILY SSF56801 14 382 1.2E-58 T 29-03-2018 CB4_RS18085 25cc8383922dee53787699d1f656aac8 442 Pfam PF14535 AMP-binding enzyme C-terminal domain 335 436 9.7E-23 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal CB4_RS11465 42d0701933d4d4f3c0e1da96d735c79d 330 Gene3D G3DSA:3.90.1690.10 3 330 1.1E-45 T 29-03-2018 CB4_RS11465 42d0701933d4d4f3c0e1da96d735c79d 330 Pfam PF03864 Phage major capsid protein E 155 218 1.1E-5 T 29-03-2018 IPR005564 Major capsid protein GpE GO:0019028 CB4_RS16685 cd9b55319e8e11c700bd4d592ac42451 209 SUPERFAMILY SSF48498 89 201 2.79E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS16685 cd9b55319e8e11c700bd4d592ac42451 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 6.3E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS16685 cd9b55319e8e11c700bd4d592ac42451 209 SUPERFAMILY SSF46689 3 66 1.8E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS16685 cd9b55319e8e11c700bd4d592ac42451 209 Gene3D G3DSA:1.10.357.10 62 202 3.9E-9 T 29-03-2018 CB4_RS16685 cd9b55319e8e11c700bd4d592ac42451 209 Gene3D G3DSA:1.10.10.60 6 61 8.6E-19 T 29-03-2018 CB4_RS16685 cd9b55319e8e11c700bd4d592ac42451 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS16685 cd9b55319e8e11c700bd4d592ac42451 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS20470 9bee66393ebbaa85fd16d16e370a49c9 741 SUPERFAMILY SSF53649 249 348 6.98E-6 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CB4_RS20470 9bee66393ebbaa85fd16d16e370a49c9 741 Gene3D G3DSA:3.40.720.10 291 370 3.7E-7 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CB4_RS19350 b13921a477a19965799f32b1cd3bbc21 235 Gene3D G3DSA:3.40.50.620 2 235 2.1E-47 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS19350 b13921a477a19965799f32b1cd3bbc21 235 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 2 235 41.562 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CB4_RS19350 b13921a477a19965799f32b1cd3bbc21 235 PIRSF PIRSF000857 2 235 1.6E-91 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CB4_RS19350 b13921a477a19965799f32b1cd3bbc21 235 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 210 7.6E-51 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CB4_RS19350 b13921a477a19965799f32b1cd3bbc21 235 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 45 233 2.2E-73 T 29-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CB4_RS19350 b13921a477a19965799f32b1cd3bbc21 235 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 26 234 1.1E-88 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CB4_RS19350 b13921a477a19965799f32b1cd3bbc21 235 SUPERFAMILY SSF52402 13 198 1.05E-52 T 29-03-2018 CB4_RS04455 014d522b5253479148591fe7726e14cb 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 240 253 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CB4_RS04455 014d522b5253479148591fe7726e14cb 396 Gene3D G3DSA:3.40.640.10 50 307 6.7E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS04455 014d522b5253479148591fe7726e14cb 396 Gene3D G3DSA:3.90.1150.10 308 391 1.8E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS04455 014d522b5253479148591fe7726e14cb 396 SUPERFAMILY SSF53383 7 390 2.18E-107 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS04455 014d522b5253479148591fe7726e14cb 396 Pfam PF00155 Aminotransferase class I and II 35 387 2.9E-59 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS01715 c1512d07db129220f59712c3261ec52f 236 SUPERFAMILY SSF53474 8 227 1.26E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS01715 c1512d07db129220f59712c3261ec52f 236 Pfam PF12697 Alpha/beta hydrolase family 9 223 1.5E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS01715 c1512d07db129220f59712c3261ec52f 236 Gene3D G3DSA:3.40.50.1820 2 230 3.3E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS12735 575e7156407093d7403a2ce2cd6905dc 333 Pfam PF03601 Conserved hypothetical protein 698 15 313 1.1E-81 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CB4_RS12525 f914c71307e28de8e05a5d96380c1130 288 Gene3D G3DSA:1.10.443.10 114 274 2.0E-19 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS12525 f914c71307e28de8e05a5d96380c1130 288 Gene3D G3DSA:1.10.150.130 6 113 1.5E-17 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CB4_RS12525 f914c71307e28de8e05a5d96380c1130 288 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 10 88 4.5E-11 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CB4_RS12525 f914c71307e28de8e05a5d96380c1130 288 SUPERFAMILY SSF56349 9 269 4.41E-33 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS12525 f914c71307e28de8e05a5d96380c1130 288 Pfam PF00589 Phage integrase family 116 269 2.6E-12 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS02150 46c9bda512fbd596ac7bd62966d8db73 167 Pfam PF04542 Sigma-70 region 2 12 79 9.0E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS02150 46c9bda512fbd596ac7bd62966d8db73 167 SUPERFAMILY SSF88946 10 92 3.26E-17 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS02150 46c9bda512fbd596ac7bd62966d8db73 167 Pfam PF08281 Sigma-70, region 4 104 154 3.7E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS02150 46c9bda512fbd596ac7bd62966d8db73 167 Gene3D G3DSA:1.10.1740.10 3 78 6.9E-15 T 29-03-2018 CB4_RS02150 46c9bda512fbd596ac7bd62966d8db73 167 Gene3D G3DSA:1.10.10.10 79 163 4.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02150 46c9bda512fbd596ac7bd62966d8db73 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 157 3.5E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS02150 46c9bda512fbd596ac7bd62966d8db73 167 SUPERFAMILY SSF88659 98 158 7.48E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS07615 10776b9c8335ea00ad63e7f1fe7c3a94 148 PRINTS PR01438 Universal stress protein signature 126 148 5.7E-20 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS07615 10776b9c8335ea00ad63e7f1fe7c3a94 148 PRINTS PR01438 Universal stress protein signature 108 120 5.7E-20 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS07615 10776b9c8335ea00ad63e7f1fe7c3a94 148 PRINTS PR01438 Universal stress protein signature 2 20 5.7E-20 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS07615 10776b9c8335ea00ad63e7f1fe7c3a94 148 Pfam PF00582 Universal stress protein family 1 148 4.1E-31 T 29-03-2018 IPR006016 UspA GO:0006950 CB4_RS07615 10776b9c8335ea00ad63e7f1fe7c3a94 148 SUPERFAMILY SSF52402 2 148 5.61E-37 T 29-03-2018 CB4_RS07615 10776b9c8335ea00ad63e7f1fe7c3a94 148 Gene3D G3DSA:3.40.50.620 1 148 1.5E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS14250 64f185eea0a275be75b019f3cf22c2c4 317 Gene3D G3DSA:3.40.1190.20 1 300 3.7E-39 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS14250 64f185eea0a275be75b019f3cf22c2c4 317 SUPERFAMILY SSF53613 5 296 6.24E-42 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS14250 64f185eea0a275be75b019f3cf22c2c4 317 Pfam PF00294 pfkB family carbohydrate kinase 4 295 2.4E-44 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CB4_RS15900 fbe868d3944f31a34073632f8003ea1b 375 SUPERFAMILY SSF56784 3 375 6.06E-39 T 29-03-2018 IPR023214 HAD-like domain CB4_RS15900 fbe868d3944f31a34073632f8003ea1b 375 Pfam PF13419 Haloacid dehalogenase-like hydrolase 222 342 1.9E-9 T 29-03-2018 IPR023214 HAD-like domain CB4_RS15900 fbe868d3944f31a34073632f8003ea1b 375 Gene3D G3DSA:3.40.50.1000 2 50 0.0032 T 29-03-2018 IPR023214 HAD-like domain CB4_RS15900 fbe868d3944f31a34073632f8003ea1b 375 Gene3D G3DSA:3.40.50.1000 211 375 2.0E-22 T 29-03-2018 IPR023214 HAD-like domain CB4_RS06110 3f1177cc952428a439a790db21105116 140 Gene3D G3DSA:3.30.420.140 1 138 3.0E-48 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CB4_RS06110 3f1177cc952428a439a790db21105116 140 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 136 26.86 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CB4_RS06110 3f1177cc952428a439a790db21105116 140 Pfam PF03652 Holliday junction resolvase 1 133 3.0E-46 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CB4_RS06110 3f1177cc952428a439a790db21105116 140 SUPERFAMILY SSF53098 1 135 6.37E-45 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS06110 3f1177cc952428a439a790db21105116 140 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 133 9.0E-50 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CB4_RS06110 3f1177cc952428a439a790db21105116 140 SMART SM00732 1 101 9.9E-40 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CB4_RS09925 34f851e921c9788d508b6af9a2aecbf9 250 Pfam PF07722 Peptidase C26 11 227 1.1E-58 T 29-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CB4_RS09925 34f851e921c9788d508b6af9a2aecbf9 250 SUPERFAMILY SSF52317 9 246 4.03E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS09925 34f851e921c9788d508b6af9a2aecbf9 250 Gene3D G3DSA:3.40.50.880 7 250 3.3E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS18890 5623a79f6ca0f1acaf4475cfbb25089a 361 SUPERFAMILY SSF53300 212 345 5.56E-5 T 29-03-2018 IPR002035 von Willebrand factor, type A CB4_RS18890 5623a79f6ca0f1acaf4475cfbb25089a 361 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 7 347 4.6E-172 T 29-03-2018 IPR014230 Sporulation protein YhbH CB4_RS18890 5623a79f6ca0f1acaf4475cfbb25089a 361 Pfam PF04285 Protein of unknown function (DUF444) 192 339 1.2E-65 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 CB4_RS18890 5623a79f6ca0f1acaf4475cfbb25089a 361 Pfam PF04285 Protein of unknown function (DUF444) 12 183 3.2E-36 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 CB4_RS18890 5623a79f6ca0f1acaf4475cfbb25089a 361 Gene3D G3DSA:3.40.50.410 206 350 5.0E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A CB4_RS13485 b0c06e433383bd5887228cfbed1cc2fa 252 Pfam PF03744 6-carboxyhexanoate--CoA ligase 7 251 5.7E-83 T 29-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 CB4_RS13485 b0c06e433383bd5887228cfbed1cc2fa 252 TIGRFAM TIGR01204 bioW: 6-carboxyhexanoate--CoA ligase 22 251 7.0E-86 T 29-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 CB4_RS13485 b0c06e433383bd5887228cfbed1cc2fa 252 Hamap MF_00668 6-carboxyhexanoate--CoA ligase [bioW]. 6 252 48.685 T 29-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 CB4_RS13485 b0c06e433383bd5887228cfbed1cc2fa 252 ProDom PD017229 LIGASE SYNTHASE BIOTIN MAGNESIUM PIMELOYL-COA 6-CARBOXYHEXANOATE--COA BIOSYNTHESIS 6-CARBOXYHEXANOATE-COA BIOW COA 5 225 7.0E-53 T 29-03-2018 IPR005499 6-carboxyhexanoate--CoA ligase GO:0005524|GO:0009102|GO:0042410 KEGG: 00780+6.2.1.14|MetaCyc: PWY-6578 CB4_RS05050 2343ebd9b9fdca17c05070137e4aaa74 224 Pfam PF00395 S-layer homology domain 34 72 8.8E-4 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS06635 3d356950e8de988ba265663d4408a2ef 370 Hamap MF_00626 Germination protease [gpr]. 1 370 148.166 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CB4_RS06635 3d356950e8de988ba265663d4408a2ef 370 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 10 370 8.0E-130 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CB4_RS06635 3d356950e8de988ba265663d4408a2ef 370 PIRSF PIRSF019549 3 370 7.9E-161 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CB4_RS06635 3d356950e8de988ba265663d4408a2ef 370 TIGRFAM TIGR01441 GPR: GPR endopeptidase 10 370 3.2E-154 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CB4_RS06635 3d356950e8de988ba265663d4408a2ef 370 Pfam PF03418 Germination protease 17 369 7.1E-161 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CB4_RS06635 3d356950e8de988ba265663d4408a2ef 370 Gene3D G3DSA:3.40.50.1450 8 366 2.8E-123 T 29-03-2018 IPR023430 Peptidase HybD-like domain CB4_RS06635 3d356950e8de988ba265663d4408a2ef 370 SUPERFAMILY SSF53163 3 370 3.66E-118 T 29-03-2018 IPR023430 Peptidase HybD-like domain CB4_RS05125 43c2e47411a0abf86edeb226ccb5c2b3 394 Gene3D G3DSA:3.40.50.2300 206 377 7.4E-26 T 29-03-2018 CB4_RS05125 43c2e47411a0abf86edeb226ccb5c2b3 394 Pfam PF13458 Periplasmic binding protein 42 389 1.1E-64 T 29-03-2018 IPR028081 Leucine-binding protein domain CB4_RS05125 43c2e47411a0abf86edeb226ccb5c2b3 394 SUPERFAMILY SSF53822 41 393 2.09E-86 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS05125 43c2e47411a0abf86edeb226ccb5c2b3 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 84 102 3.7E-7 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CB4_RS05125 43c2e47411a0abf86edeb226ccb5c2b3 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 270 288 3.7E-7 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CB4_RS05125 43c2e47411a0abf86edeb226ccb5c2b3 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 43 59 3.7E-7 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CB4_RS05125 43c2e47411a0abf86edeb226ccb5c2b3 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 65 81 3.7E-7 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CB4_RS05125 43c2e47411a0abf86edeb226ccb5c2b3 394 Gene3D G3DSA:3.40.50.2300 26 205 6.1E-35 T 29-03-2018 CB4_RS19530 d741d54138639096ae438da9885bfb8d 577 SUPERFAMILY SSF53756 128 490 1.16E-67 T 29-03-2018 CB4_RS19530 d741d54138639096ae438da9885bfb8d 577 Pfam PF11997 Domain of unknown function (DUF3492) 11 288 1.2E-44 T 29-03-2018 IPR022622 Domain of unknown function DUF3492 CB4_RS19530 d741d54138639096ae438da9885bfb8d 577 Gene3D G3DSA:3.40.50.2000 125 301 6.4E-7 T 29-03-2018 CB4_RS19530 d741d54138639096ae438da9885bfb8d 577 Pfam PF00534 Glycosyl transferases group 1 315 469 3.8E-34 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CB4_RS19530 d741d54138639096ae438da9885bfb8d 577 Gene3D G3DSA:3.40.50.2000 302 475 8.0E-45 T 29-03-2018 CB4_RS19530 d741d54138639096ae438da9885bfb8d 577 SUPERFAMILY SSF48452 508 573 6.96E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS19530 d741d54138639096ae438da9885bfb8d 577 Gene3D G3DSA:1.25.40.10 505 576 5.4E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS07375 c4267dfcd1ee4617666301fd51634607 174 Gene3D G3DSA:3.40.30.10 20 169 1.9E-36 T 29-03-2018 CB4_RS07375 c4267dfcd1ee4617666301fd51634607 174 ProSitePatterns PS00194 Thioredoxin family active site. 64 82 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CB4_RS07375 c4267dfcd1ee4617666301fd51634607 174 Pfam PF00578 AhpC/TSA family 37 152 1.5E-22 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS07375 c4267dfcd1ee4617666301fd51634607 174 SUPERFAMILY SSF52833 1 169 1.13E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 471 1.0E-157 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 352 460 3.7E-32 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 SUPERFAMILY SSF51905 8 341 2.93E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PIRSF PIRSF000350 3 465 1.1E-84 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 Gene3D G3DSA:3.50.50.60 159 280 4.1E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 Gene3D G3DSA:3.50.50.60 281 345 3.6E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 Gene3D G3DSA:3.30.390.30 351 474 7.4E-39 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 333 2.3E-71 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 SUPERFAMILY SSF55424 351 471 8.08E-39 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 Gene3D G3DSA:3.50.50.60 6 158 1.7E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 285 7.9E-37 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 320 7.9E-37 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 7.9E-37 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 7.9E-37 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 7.9E-37 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 284 7.1E-69 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 7.1E-69 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 7.1E-69 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 435 455 7.1E-69 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 313 320 7.1E-69 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 7.1E-69 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 428 7.1E-69 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 348 369 7.1E-69 T 29-03-2018 CB4_RS19735 8385eb2c46e36d4f53549d81d73292b8 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 7.1E-69 T 29-03-2018 CB4_RS03535 9300e11b7269e4d79e68bcc37fc59d08 78 Pfam PF04899 MbeD/MobD like 1 69 1.1E-4 T 29-03-2018 IPR006983 MbeD/MobD-like CB4_RS03535 9300e11b7269e4d79e68bcc37fc59d08 78 Gene3D G3DSA:3.90.20.10 1 78 1.4E-7 T 29-03-2018 CB4_RS06780 b0e075db8916ae0efa21a090d2df2ba2 543 SUPERFAMILY SSF81606 10 241 4.45E-22 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS06780 b0e075db8916ae0efa21a090d2df2ba2 543 Gene3D G3DSA:1.25.40.10 275 451 0.0014 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS06780 b0e075db8916ae0efa21a090d2df2ba2 543 Gene3D G3DSA:3.60.40.10 2 258 8.5E-16 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CB4_RS06780 b0e075db8916ae0efa21a090d2df2ba2 543 Gene3D G3DSA:1.10.150.160 452 525 0.012 T 29-03-2018 CB4_RS08215 9d68544df46987ec33fba909c367d82c 312 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 309 9.3E-121 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS08215 9d68544df46987ec33fba909c367d82c 312 PIRSF PIRSF004486 1 311 3.7E-109 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS08215 9d68544df46987ec33fba909c367d82c 312 Gene3D G3DSA:3.40.50.150 6 102 0.0013 T 29-03-2018 CB4_RS08215 9d68544df46987ec33fba909c367d82c 312 SUPERFAMILY SSF81799 113 214 8.24E-34 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS08215 9d68544df46987ec33fba909c367d82c 312 SUPERFAMILY SSF53335 214 310 4.65E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS08215 9d68544df46987ec33fba909c367d82c 312 SUPERFAMILY SSF53335 3 112 4.65E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS08215 9d68544df46987ec33fba909c367d82c 312 Gene3D G3DSA:1.10.150.170 111 216 3.6E-38 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS08215 9d68544df46987ec33fba909c367d82c 312 Pfam PF01795 MraW methylase family 2 309 2.2E-130 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS08215 9d68544df46987ec33fba909c367d82c 312 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 38.804 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS06995 b3d25ec04eae0dd65c69b27fa07c3fd1 158 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 43 146 1.5E-13 T 29-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 470 3.0E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 412 3.0E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 426 3.0E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 3.0E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 312 2.5E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 SMART SM00387 357 471 2.8E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 SUPERFAMILY SSF47384 234 312 3.14E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 SMART SM00388 245 312 8.1E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 SUPERFAMILY SSF55874 301 470 4.98E-49 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 Gene3D G3DSA:1.10.287.130 237 308 9.5E-14 T 29-03-2018 CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 Gene3D G3DSA:3.30.565.10 316 471 9.7E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13280 c0eb7399fd4c92b344da3111f4972d45 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 470 2.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS14025 3ef4bb73d0e5698ceef9e4504462117a 367 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 246 316 1.2E-13 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS14025 3ef4bb73d0e5698ceef9e4504462117a 367 Pfam PF07282 Putative transposase DNA-binding domain 289 359 4.0E-23 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS14025 3ef4bb73d0e5698ceef9e4504462117a 367 Pfam PF12323 Helix-turn-helix domain 1 48 4.0E-20 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CB4_RS14025 3ef4bb73d0e5698ceef9e4504462117a 367 Pfam PF01385 Probable transposase 167 275 1.0E-23 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS13480 9709f01d9c6d55915c40837cc0e7add7 384 Gene3D G3DSA:3.40.640.10 3 274 7.4E-60 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS13480 9709f01d9c6d55915c40837cc0e7add7 384 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 228 237 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CB4_RS13480 9709f01d9c6d55915c40837cc0e7add7 384 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 25 372 9.8E-146 T 29-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 CB4_RS13480 9709f01d9c6d55915c40837cc0e7add7 384 Gene3D G3DSA:3.90.1150.10 275 382 5.3E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS13480 9709f01d9c6d55915c40837cc0e7add7 384 SUPERFAMILY SSF53383 7 381 7.89E-114 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS13480 9709f01d9c6d55915c40837cc0e7add7 384 Pfam PF00155 Aminotransferase class I and II 35 372 2.4E-75 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS15850 407d807359235b8021b884b38abd813b 543 Pfam PF10101 Predicted membrane protein (DUF2339) 65 383 1.2E-31 T 29-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane CB4_RS15850 407d807359235b8021b884b38abd813b 543 Pfam PF10101 Predicted membrane protein (DUF2339) 401 531 4.0E-13 T 29-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane CB4_RS12780 3fb9ca8a6cbc1f2f8b87c44a739b2be4 132 Pfam PF01230 HIT domain 10 102 2.8E-22 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CB4_RS12780 3fb9ca8a6cbc1f2f8b87c44a739b2be4 132 PRINTS PR00332 Histidine triad family signature 21 39 1.0E-6 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CB4_RS12780 3fb9ca8a6cbc1f2f8b87c44a739b2be4 132 PRINTS PR00332 Histidine triad family signature 88 98 1.0E-6 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CB4_RS12780 3fb9ca8a6cbc1f2f8b87c44a739b2be4 132 Gene3D G3DSA:3.30.428.10 1 128 9.8E-38 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CB4_RS12780 3fb9ca8a6cbc1f2f8b87c44a739b2be4 132 ProSitePatterns PS00892 HIT domain signature. 81 99 - T 29-03-2018 IPR019808 Histidine triad, conserved site CB4_RS12780 3fb9ca8a6cbc1f2f8b87c44a739b2be4 132 SUPERFAMILY SSF54197 2 126 4.49E-39 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CB4_RS03655 cf52056538fcedc0b19cb9d57b6c5243 164 Gene3D G3DSA:2.160.10.10 29 161 1.1E-28 T 29-03-2018 CB4_RS03655 cf52056538fcedc0b19cb9d57b6c5243 164 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 108 137 2.0E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS03655 cf52056538fcedc0b19cb9d57b6c5243 164 SUPERFAMILY SSF51161 11 161 1.37E-35 T 29-03-2018 IPR011004 Trimeric LpxA-like CB4_RS17360 f9dfb1fa13765c96b0cb480f10dc4094 106 Gene3D G3DSA:3.40.30.10 1 103 1.1E-36 T 29-03-2018 CB4_RS17360 f9dfb1fa13765c96b0cb480f10dc4094 106 Pfam PF11009 Protein of unknown function (DUF2847) 3 101 3.3E-35 T 29-03-2018 IPR022551 Protein of unknown function DUF2847 CB4_RS17360 f9dfb1fa13765c96b0cb480f10dc4094 106 SUPERFAMILY SSF52833 2 91 3.48E-7 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS17360 f9dfb1fa13765c96b0cb480f10dc4094 106 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 3 102 1.4E-35 T 29-03-2018 IPR022551 Protein of unknown function DUF2847 CB4_RS15175 d942a00f87beeb68e6dc10af049d9ad0 287 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 3 285 2.7E-96 T 29-03-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related CB4_RS15175 d942a00f87beeb68e6dc10af049d9ad0 287 Pfam PF01040 UbiA prenyltransferase family 24 269 1.6E-53 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CB4_RS00875 6545220f43391a2db50233034a816771 122 Gene3D G3DSA:3.30.420.100 1 122 2.8E-46 T 29-03-2018 CB4_RS00875 6545220f43391a2db50233034a816771 122 SUPERFAMILY SSF53137 7 120 2.62E-58 T 29-03-2018 CB4_RS00875 6545220f43391a2db50233034a816771 122 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 122 8.1E-47 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00875 6545220f43391a2db50233034a816771 122 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 122 2.3E-50 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00875 6545220f43391a2db50233034a816771 122 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 122 30.485 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS13600 a546f6bd93012a969791319b9643a32a 272 SUPERFAMILY SSF69618 7 267 5.36E-54 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS13600 a546f6bd93012a969791319b9643a32a 272 Pfam PF02602 Uroporphyrinogen-III synthase HemD 20 259 3.9E-41 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CB4_RS13600 a546f6bd93012a969791319b9643a32a 272 Gene3D G3DSA:3.40.50.10090 165 269 9.5E-16 T 29-03-2018 CB4_RS13600 a546f6bd93012a969791319b9643a32a 272 Gene3D G3DSA:3.40.50.10090 42 164 1.3E-18 T 29-03-2018 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 4 285 9.0E-112 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 285 37.148 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 SUPERFAMILY SSF52943 4 285 8.24E-96 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 Gene3D G3DSA:1.10.287.80 4 42 2.3E-20 T 29-03-2018 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 Gene3D G3DSA:1.10.287.80 239 280 1.7E-13 T 29-03-2018 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 PRINTS PR00126 ATP synthase gamma subunit signature 232 251 5.7E-41 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 5.7E-41 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 5.7E-41 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 PRINTS PR00126 ATP synthase gamma subunit signature 263 284 5.7E-41 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 Gene3D G3DSA:3.40.1380.10 43 238 1.0E-78 T 29-03-2018 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 271 284 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS02975 27a515805432a7ffa1290d50ff8b77de 286 Pfam PF00231 ATP synthase 5 285 4.7E-105 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CB4_RS06640 b58009acc33a9e4632e3ee6633534915 390 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 102 372 6.8E-68 T 29-03-2018 IPR010897 Sporulation stage II, protein P CB4_RS06640 b58009acc33a9e4632e3ee6633534915 390 Gene3D G3DSA:3.40.630.40 169 385 1.9E-15 T 29-03-2018 CB4_RS06640 b58009acc33a9e4632e3ee6633534915 390 SUPERFAMILY SSF53187 257 376 2.2E-9 T 29-03-2018 CB4_RS06640 b58009acc33a9e4632e3ee6633534915 390 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 173 376 5.0E-66 T 29-03-2018 IPR010897 Sporulation stage II, protein P CB4_RS10265 e78ea38dfea35f51b0c92ba8d064b123 412 Gene3D G3DSA:1.20.1250.20 7 206 4.3E-24 T 29-03-2018 CB4_RS10265 e78ea38dfea35f51b0c92ba8d064b123 412 SUPERFAMILY SSF103473 13 402 4.19E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS10265 e78ea38dfea35f51b0c92ba8d064b123 412 Gene3D G3DSA:1.20.1250.20 218 411 4.5E-19 T 29-03-2018 CB4_RS10265 e78ea38dfea35f51b0c92ba8d064b123 412 Pfam PF05977 Transmembrane secretion effector 11 403 4.7E-21 T 29-03-2018 IPR010290 Transmembrane secretion effector CB4_RS13845 7b71796f3058f9922df9c3e1e34cf43f 57 Pfam PF14152 YfhE-like protein 16 40 2.8E-10 T 29-03-2018 IPR025437 YfhE-like protein CB4_RS03430 11787e092bbf99b15bcd0ce8d510d078 555 Pfam PF00700 Bacterial flagellin C-terminal helical region 469 554 6.8E-27 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CB4_RS03430 11787e092bbf99b15bcd0ce8d510d078 555 Gene3D G3DSA:1.20.1330.10 38 527 8.6E-67 T 29-03-2018 CB4_RS03430 11787e092bbf99b15bcd0ce8d510d078 555 SUPERFAMILY SSF64518 245 555 1.06E-92 T 29-03-2018 CB4_RS03430 11787e092bbf99b15bcd0ce8d510d078 555 SUPERFAMILY SSF64518 1 187 1.06E-92 T 29-03-2018 CB4_RS03430 11787e092bbf99b15bcd0ce8d510d078 555 PRINTS PR00207 Flagellin signature 109 132 7.7E-25 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CB4_RS03430 11787e092bbf99b15bcd0ce8d510d078 555 PRINTS PR00207 Flagellin signature 35 52 7.7E-25 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CB4_RS03430 11787e092bbf99b15bcd0ce8d510d078 555 PRINTS PR00207 Flagellin signature 74 93 7.7E-25 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CB4_RS03430 11787e092bbf99b15bcd0ce8d510d078 555 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 138 1.5E-44 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CB4_RS07860 8ece5289223ab66d6365cd55d193c514 296 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 38 277 2.0E-84 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 CB4_RS07860 8ece5289223ab66d6365cd55d193c514 296 Pfam PF07136 Protein of unknown function (DUF1385) 38 280 4.2E-80 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 CB4_RS15455 5501d488b8377f50cdead3cab2904411 136 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 30 123 1.1E-7 T 29-03-2018 IPR014986 Clostridium phage phiCD119, XkdN CB4_RS03310 7600f197f9141712f5cf1f6c29dac314 932 Gene3D G3DSA:2.60.40.1310 81 230 2.5E-4 T 29-03-2018 CB4_RS03310 7600f197f9141712f5cf1f6c29dac314 932 Gene3D G3DSA:2.60.40.10 819 928 2.7E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS17595 5ec59f2f0643a3e3457401363f1d19a4 393 Gene3D G3DSA:3.40.50.2300 36 209 1.5E-38 T 29-03-2018 CB4_RS17595 5ec59f2f0643a3e3457401363f1d19a4 393 Pfam PF13458 Periplasmic binding protein 39 387 3.0E-69 T 29-03-2018 IPR028081 Leucine-binding protein domain CB4_RS17595 5ec59f2f0643a3e3457401363f1d19a4 393 SUPERFAMILY SSF53822 38 390 1.81E-85 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS17595 5ec59f2f0643a3e3457401363f1d19a4 393 Gene3D G3DSA:3.40.50.2300 210 375 1.7E-21 T 29-03-2018 CB4_RS17595 5ec59f2f0643a3e3457401363f1d19a4 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 40 56 1.6E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CB4_RS17595 5ec59f2f0643a3e3457401363f1d19a4 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 267 285 1.6E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CB4_RS17595 5ec59f2f0643a3e3457401363f1d19a4 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 81 99 1.6E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CB4_RS17595 5ec59f2f0643a3e3457401363f1d19a4 393 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 62 78 1.6E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CB4_RS03005 0141bd095deb980a6bd997b6d73af59e 239 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 119 232 4.0E-37 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03005 0141bd095deb980a6bd997b6d73af59e 239 Gene3D G3DSA:1.10.601.10 1 166 7.4E-4 T 29-03-2018 CB4_RS03005 0141bd095deb980a6bd997b6d73af59e 239 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 197 218 - T 29-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03005 0141bd095deb980a6bd997b6d73af59e 239 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 118 233 1.8E-40 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03005 0141bd095deb980a6bd997b6d73af59e 239 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 170 225 4.0E-16 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03005 0141bd095deb980a6bd997b6d73af59e 239 SUPERFAMILY SSF143243 91 235 3.53E-43 T 29-03-2018 CB4_RS12165 0bbbeb9e0aac64a4caa021a870dbf823 128 Gene3D G3DSA:3.30.429.10 1 127 2.3E-43 T 29-03-2018 CB4_RS12165 0bbbeb9e0aac64a4caa021a870dbf823 128 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 126 1.7E-40 T 29-03-2018 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 CB4_RS12165 0bbbeb9e0aac64a4caa021a870dbf823 128 SUPERFAMILY SSF55331 2 127 1.54E-40 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CB4_RS19105 b854f3ca87343d1ad9e9d87146bd5d74 185 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 177 6.7E-56 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CB4_RS19105 b854f3ca87343d1ad9e9d87146bd5d74 185 Pfam PF01923 Cobalamin adenosyltransferase 3 169 4.9E-57 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CB4_RS19105 b854f3ca87343d1ad9e9d87146bd5d74 185 Gene3D G3DSA:1.20.1200.10 12 185 2.6E-59 T 29-03-2018 CB4_RS19105 b854f3ca87343d1ad9e9d87146bd5d74 185 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 174 1.0E-48 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CB4_RS19105 b854f3ca87343d1ad9e9d87146bd5d74 185 SUPERFAMILY SSF89028 1 177 1.96E-59 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CB4_RS08265 9927cf92d54f418908ba9f3af57a8ca2 417 Gene3D G3DSA:3.65.10.10 218 417 1.7E-45 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS08265 9927cf92d54f418908ba9f3af57a8ca2 417 SUPERFAMILY SSF55205 2 415 2.62E-128 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CB4_RS08265 9927cf92d54f418908ba9f3af57a8ca2 417 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 41.657 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS08265 9927cf92d54f418908ba9f3af57a8ca2 417 Gene3D G3DSA:3.65.10.10 21 217 3.3E-48 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS08265 9927cf92d54f418908ba9f3af57a8ca2 417 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 415 3.5E-160 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS08265 9927cf92d54f418908ba9f3af57a8ca2 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 5.0E-92 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CB4_RS07445 62769e953e74f0717748ead99f84eff1 480 Gene3D G3DSA:3.40.50.200 129 444 3.6E-98 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CB4_RS07445 62769e953e74f0717748ead99f84eff1 480 Pfam PF00082 Subtilase family 188 430 5.7E-49 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CB4_RS07445 62769e953e74f0717748ead99f84eff1 480 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 191 202 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CB4_RS07445 62769e953e74f0717748ead99f84eff1 480 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 380 390 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CB4_RS07445 62769e953e74f0717748ead99f84eff1 480 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 228 238 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CB4_RS07445 62769e953e74f0717748ead99f84eff1 480 PRINTS PR00723 Subtilisin serine protease family (S8) signature 224 237 4.8E-18 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CB4_RS07445 62769e953e74f0717748ead99f84eff1 480 PRINTS PR00723 Subtilisin serine protease family (S8) signature 186 205 4.8E-18 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CB4_RS07445 62769e953e74f0717748ead99f84eff1 480 PRINTS PR00723 Subtilisin serine protease family (S8) signature 379 395 4.8E-18 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CB4_RS07445 62769e953e74f0717748ead99f84eff1 480 SUPERFAMILY SSF52743 166 443 2.09E-96 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CB4_RS09495 e9d08656719685c9b5ea0126ae2a2dab 516 SUPERFAMILY SSF48239 234 514 2.67E-68 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CB4_RS09495 e9d08656719685c9b5ea0126ae2a2dab 516 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 240 422 1.1E-49 T 29-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CB4_RS09495 e9d08656719685c9b5ea0126ae2a2dab 516 Gene3D G3DSA:1.50.10.20 103 227 1.4E-13 T 29-03-2018 CB4_RS09495 e9d08656719685c9b5ea0126ae2a2dab 516 Gene3D G3DSA:1.50.10.20 36 102 2.7E-8 T 29-03-2018 CB4_RS09495 e9d08656719685c9b5ea0126ae2a2dab 516 SUPERFAMILY SSF48239 39 234 1.81E-20 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CB4_RS09495 e9d08656719685c9b5ea0126ae2a2dab 516 Gene3D G3DSA:1.50.10.20 228 424 6.1E-52 T 29-03-2018 CB4_RS09495 e9d08656719685c9b5ea0126ae2a2dab 516 Gene3D G3DSA:1.50.10.20 425 516 6.9E-18 T 29-03-2018 CB4_RS09495 e9d08656719685c9b5ea0126ae2a2dab 516 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 101 228 3.3E-21 T 29-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CB4_RS12120 55a97a272798692831eaa9420523bd16 512 PIRSF PIRSF005690 24 507 9.4E-182 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS12120 55a97a272798692831eaa9420523bd16 512 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 38 491 3.1E-177 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS09675 11c5e59d964174f5452465289e15daa4 613 Gene3D G3DSA:3.40.50.10490 455 613 1.1E-41 T 29-03-2018 CB4_RS09675 11c5e59d964174f5452465289e15daa4 613 Pfam PF13522 Glutamine amidotransferase domain 63 193 6.5E-25 T 29-03-2018 CB4_RS09675 11c5e59d964174f5452465289e15daa4 613 SUPERFAMILY SSF53697 248 613 2.97E-99 T 29-03-2018 CB4_RS09675 11c5e59d964174f5452465289e15daa4 613 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 613 36.004 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CB4_RS09675 11c5e59d964174f5452465289e15daa4 613 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 3 613 1.6E-209 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CB4_RS09675 11c5e59d964174f5452465289e15daa4 613 Gene3D G3DSA:3.60.20.10 3 231 3.0E-57 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS09675 11c5e59d964174f5452465289e15daa4 613 Pfam PF01380 SIS domain 292 419 8.7E-30 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CB4_RS09675 11c5e59d964174f5452465289e15daa4 613 Pfam PF01380 SIS domain 466 592 1.7E-25 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CB4_RS09675 11c5e59d964174f5452465289e15daa4 613 SUPERFAMILY SSF56235 3 228 1.63E-63 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS09675 11c5e59d964174f5452465289e15daa4 613 Gene3D G3DSA:3.40.50.10490 251 454 2.3E-57 T 29-03-2018 CB4_RS07295 48611ab4ccf94658bfb52ca925cd25f7 117 Gene3D G3DSA:1.25.40.10 15 107 3.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 SUPERFAMILY SSF49373 1012 1095 2.59E-16 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF07532 Bacterial Ig-like domain (group 4) 444 497 3.6E-6 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF07532 Bacterial Ig-like domain (group 4) 935 982 3.2E-6 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF07532 Bacterial Ig-like domain (group 4) 742 788 7.5E-7 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF07532 Bacterial Ig-like domain (group 4) 838 885 3.3E-6 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF07532 Bacterial Ig-like domain (group 4) 643 691 5.8E-6 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF07532 Bacterial Ig-like domain (group 4) 543 594 3.7E-6 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Gene3D G3DSA:2.60.40.1080 1102 1189 3.8E-23 T 29-03-2018 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Gene3D G3DSA:2.60.40.1080 1014 1098 2.9E-18 T 29-03-2018 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Gene3D G3DSA:2.60.40.10 530 623 0.0088 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Gene3D G3DSA:2.60.40.10 917 1013 0.34 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Gene3D G3DSA:2.60.40.10 820 914 0.0096 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Gene3D G3DSA:2.60.40.10 432 526 0.33 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Gene3D G3DSA:2.60.40.10 626 720 0.13 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Gene3D G3DSA:2.60.40.10 723 817 0.17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Gene3D G3DSA:2.60.120.640 202 326 8.8E-6 T 29-03-2018 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 SMART SM00635 1106 1183 1.6E-14 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 SMART SM00635 1014 1091 1.7E-11 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF00395 S-layer homology domain 1456 1498 2.7E-14 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF00395 S-layer homology domain 1583 1624 4.2E-7 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF00395 S-layer homology domain 1517 1560 2.3E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 SUPERFAMILY SSF49373 1104 1186 3.3E-16 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF02368 Bacterial Ig-like domain (group 2) 1015 1090 2.1E-9 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Pfam PF02368 Bacterial Ig-like domain (group 2) 1107 1183 1.0E-9 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS06200 941c59e0c989275acc2320a8216fb50c 1640 Gene3D G3DSA:2.60.500.10 327 430 2.3E-13 T 29-03-2018 CB4_RS01990 2ddb6293bc8f38d521583e65c31d35d7 67 Pfam PF06107 Bacterial protein of unknown function (DUF951) 7 59 3.0E-31 T 29-03-2018 IPR009296 Protein of unknown function DUF951 CB4_RS01990 2ddb6293bc8f38d521583e65c31d35d7 67 PIRSF PIRSF037263 1 66 2.2E-35 T 29-03-2018 IPR009296 Protein of unknown function DUF951 CB4_RS09540 62ac4a31da04d501c94ced8a4b988f63 218 Gene3D G3DSA:1.10.10.60 2 48 2.3E-17 T 29-03-2018 CB4_RS09540 62ac4a31da04d501c94ced8a4b988f63 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 61 2.5E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS09540 62ac4a31da04d501c94ced8a4b988f63 218 Gene3D G3DSA:1.10.10.60 49 166 8.0E-9 T 29-03-2018 CB4_RS09540 62ac4a31da04d501c94ced8a4b988f63 218 SUPERFAMILY SSF46689 3 66 2.0E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS12435 6e469909c2cf0477f2c9c23be60fb43c 332 Gene3D G3DSA:4.10.860.10 179 226 7.9E-5 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS12435 6e469909c2cf0477f2c9c23be60fb43c 332 SMART SM00465 16 98 5.8E-13 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS12435 6e469909c2cf0477f2c9c23be60fb43c 332 Gene3D G3DSA:3.40.1440.10 10 101 3.8E-21 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS12435 6e469909c2cf0477f2c9c23be60fb43c 332 Pfam PF02151 UvrB/uvrC motif 203 229 2.5E-4 T 29-03-2018 IPR001943 UVR domain GO:0005515 CB4_RS12435 6e469909c2cf0477f2c9c23be60fb43c 332 SUPERFAMILY SSF82771 16 99 2.48E-21 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS12435 6e469909c2cf0477f2c9c23be60fb43c 332 Pfam PF01541 GIY-YIG catalytic domain 16 93 2.6E-12 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CB4_RS05000 a050b754de1b5d5ae8be85eee5b65d57 366 Gene3D G3DSA:3.30.457.10 25 65 3.3E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS05000 a050b754de1b5d5ae8be85eee5b65d57 366 Gene3D G3DSA:3.30.457.10 66 201 5.2E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS05000 a050b754de1b5d5ae8be85eee5b65d57 366 Pfam PF07833 Copper amine oxidase N-terminal domain 166 208 1.2E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS05000 a050b754de1b5d5ae8be85eee5b65d57 366 Pfam PF07833 Copper amine oxidase N-terminal domain 55 87 1.7E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS14135 7e3f50f0b23b02604107132c3c754c5d 238 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 114 237 1.8E-59 T 29-03-2018 IPR014258 CAP domain, YkwD-like CB4_RS14135 7e3f50f0b23b02604107132c3c754c5d 238 Gene3D G3DSA:3.40.33.10 111 237 7.9E-17 T 29-03-2018 IPR014044 CAP domain CB4_RS14135 7e3f50f0b23b02604107132c3c754c5d 238 SUPERFAMILY SSF55797 114 237 8.5E-24 T 29-03-2018 IPR014044 CAP domain CB4_RS14135 7e3f50f0b23b02604107132c3c754c5d 238 Pfam PF00188 Cysteine-rich secretory protein family 121 236 3.4E-18 T 29-03-2018 IPR014044 CAP domain CB4_RS13985 34e6a3b240ac44a66d855a625dc9298f 294 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 1.7E-21 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CB4_RS13985 34e6a3b240ac44a66d855a625dc9298f 294 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 24 223 5.7E-68 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS13985 34e6a3b240ac44a66d855a625dc9298f 294 PIRSF PIRSF006483 3 293 2.2E-97 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS03670 82a585002c15ab3668e09039ee2b8fe0 214 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 147 168 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CB4_RS03670 82a585002c15ab3668e09039ee2b8fe0 214 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 8 212 55.363 T 29-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CB4_RS03670 82a585002c15ab3668e09039ee2b8fe0 214 Gene3D G3DSA:3.40.190.10 3 118 5.2E-38 T 29-03-2018 CB4_RS03670 82a585002c15ab3668e09039ee2b8fe0 214 SUPERFAMILY SSF53850 6 211 1.52E-66 T 29-03-2018 CB4_RS03670 82a585002c15ab3668e09039ee2b8fe0 214 Pfam PF01634 ATP phosphoribosyltransferase 58 206 4.0E-50 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CB4_RS03670 82a585002c15ab3668e09039ee2b8fe0 214 Gene3D G3DSA:3.40.190.10 119 180 2.2E-26 T 29-03-2018 CB4_RS03670 82a585002c15ab3668e09039ee2b8fe0 214 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 10 188 1.3E-61 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CB4_RS02805 5eefc968d9eca4cd065419bb2c92c578 287 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 287 8.3E-129 T 29-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CB4_RS02805 5eefc968d9eca4cd065419bb2c92c578 287 SUPERFAMILY SSF51569 1 287 9.52E-104 T 29-03-2018 CB4_RS02805 5eefc968d9eca4cd065419bb2c92c578 287 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 286 4.7E-103 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CB4_RS02805 5eefc968d9eca4cd065419bb2c92c578 287 PIRSF PIRSF001359 1 287 8.0E-126 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CB4_RS02805 5eefc968d9eca4cd065419bb2c92c578 287 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CB4_RS02805 5eefc968d9eca4cd065419bb2c92c578 287 Gene3D G3DSA:3.20.20.70 1 287 1.1E-105 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS02805 5eefc968d9eca4cd065419bb2c92c578 287 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CB4_RS02805 5eefc968d9eca4cd065419bb2c92c578 287 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 287 9.1E-113 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CB4_RS18580 66e2e7c2d6069bc88de1a7a486febe8c 236 Gene3D G3DSA:2.30.30.240 88 155 1.8E-7 T 29-03-2018 CB4_RS18580 66e2e7c2d6069bc88de1a7a486febe8c 236 Gene3D G3DSA:2.30.30.240 1 72 8.7E-11 T 29-03-2018 CB4_RS18580 66e2e7c2d6069bc88de1a7a486febe8c 236 SUPERFAMILY SSF50346 3 67 1.86E-7 T 29-03-2018 IPR011033 PRC-barrel-like CB4_RS18580 66e2e7c2d6069bc88de1a7a486febe8c 236 SUPERFAMILY SSF50346 93 152 3.92E-8 T 29-03-2018 IPR011033 PRC-barrel-like CB4_RS18580 66e2e7c2d6069bc88de1a7a486febe8c 236 Pfam PF05239 PRC-barrel domain 5 66 1.4E-6 T 29-03-2018 IPR027275 PRC-barrel domain CB4_RS18580 66e2e7c2d6069bc88de1a7a486febe8c 236 Pfam PF05239 PRC-barrel domain 93 152 8.7E-5 T 29-03-2018 IPR027275 PRC-barrel domain CB4_RS13100 23738a6d71ab809c01d9a0356df05785 261 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS13100 23738a6d71ab809c01d9a0356df05785 261 Pfam PF00005 ABC transporter 29 179 3.8E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS13100 23738a6d71ab809c01d9a0356df05785 261 SUPERFAMILY SSF52540 6 242 1.78E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13100 23738a6d71ab809c01d9a0356df05785 261 Gene3D G3DSA:3.40.50.300 1 258 1.1E-54 T 29-03-2018 CB4_RS13100 23738a6d71ab809c01d9a0356df05785 261 SMART SM00382 37 229 1.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS11300 9293b2d1fa244cbc42193f4ccb96fe53 371 Pfam PF13037 Domain of unknown function (DUF3898) 259 348 1.1E-39 T 29-03-2018 IPR025012 Domain of unknown function DUF3898 CB4_RS11300 9293b2d1fa244cbc42193f4ccb96fe53 371 Pfam PF13039 Protein of unknown function (DUF3900) 2 252 1.8E-128 T 29-03-2018 IPR025006 Protein of unknown function DUF3900 CB4_RS10335 b40c4bc9958baf73f1ebb79d74a56b92 363 Gene3D G3DSA:3.30.470.20 206 335 5.9E-12 T 29-03-2018 CB4_RS10335 b40c4bc9958baf73f1ebb79d74a56b92 363 Gene3D G3DSA:3.30.1490.20 133 205 1.9E-7 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS10335 b40c4bc9958baf73f1ebb79d74a56b92 363 Pfam PF14398 YheC/D like ATP-grasp 101 356 4.9E-60 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CB4_RS10335 b40c4bc9958baf73f1ebb79d74a56b92 363 SUPERFAMILY SSF56059 132 327 1.55E-12 T 29-03-2018 CB4_RS02190 1b570693bdc1ed3e0b02c5a8425ee385 228 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 4 224 4.5E-79 T 29-03-2018 IPR005261 Conserved hypothetical protein CHP00659 CB4_RS02190 1b570693bdc1ed3e0b02c5a8425ee385 228 Pfam PF04172 LrgB-like family 10 222 1.2E-75 T 29-03-2018 IPR007300 CidB/LrgB family CB4_RS17010 39994e4df4136ebdc684001874f07177 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 258 1.3E-60 T 29-03-2018 IPR023214 HAD-like domain CB4_RS17010 39994e4df4136ebdc684001874f07177 273 SUPERFAMILY SSF56784 1 263 4.86E-65 T 29-03-2018 IPR023214 HAD-like domain CB4_RS17010 39994e4df4136ebdc684001874f07177 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 231 7.7E-23 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CB4_RS17010 39994e4df4136ebdc684001874f07177 273 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 29-03-2018 CB4_RS17010 39994e4df4136ebdc684001874f07177 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 258 1.0E-54 T 29-03-2018 IPR000150 Cof family GO:0016787 CB4_RS17010 39994e4df4136ebdc684001874f07177 273 Gene3D G3DSA:3.40.50.1000 1 268 5.9E-41 T 29-03-2018 IPR023214 HAD-like domain CB4_RS19840 b405078989549dbb6357756a0b0afcde 143 Gene3D G3DSA:1.10.260.40 3 127 1.1E-4 T 29-03-2018 CB4_RS04995 76985421cba5dccfccff17d1cd4016fa 220 SUPERFAMILY SSF46785 6 191 2.41E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04995 76985421cba5dccfccff17d1cd4016fa 220 Gene3D G3DSA:1.10.10.10 1 155 3.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04995 76985421cba5dccfccff17d1cd4016fa 220 Pfam PF08220 DeoR-like helix-turn-helix domain 11 51 1.6E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CB4_RS05980 0ed8cdc954d44a3fb1ce6c89dac794a6 527 PIRSF PIRSF038958 1 521 1.7E-163 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CB4_RS05980 0ed8cdc954d44a3fb1ce6c89dac794a6 527 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 6 498 1.2E-150 T 29-03-2018 IPR014249 Sporulation stage V protein B CB4_RS05980 0ed8cdc954d44a3fb1ce6c89dac794a6 527 Pfam PF01943 Polysaccharide biosynthesis protein 7 309 3.3E-43 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CB4_RS05980 0ed8cdc954d44a3fb1ce6c89dac794a6 527 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 362 501 7.9E-19 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CB4_RS09460 994cac09b230b9ce5d62f3109778d35a 105 Pfam PF00589 Phage integrase family 1 39 5.2E-8 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS09460 994cac09b230b9ce5d62f3109778d35a 105 Gene3D G3DSA:1.10.443.10 1 57 2.1E-13 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS09460 994cac09b230b9ce5d62f3109778d35a 105 SUPERFAMILY SSF56349 1 49 3.83E-14 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS02220 f7bb11beef47f38762ca509cbef15e0b 273 SUPERFAMILY SSF103190 24 105 4.71E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS02220 f7bb11beef47f38762ca509cbef15e0b 273 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 138 272 1.8E-18 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02220 f7bb11beef47f38762ca509cbef15e0b 273 SUPERFAMILY SSF58104 111 271 1.44E-31 T 29-03-2018 CB4_RS02220 f7bb11beef47f38762ca509cbef15e0b 273 SMART SM00283 89 272 0.0064 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02220 f7bb11beef47f38762ca509cbef15e0b 273 Gene3D G3DSA:1.10.287.950 102 273 5.4E-30 T 29-03-2018 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 5.2E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 Gene3D G3DSA:3.50.50.60 1 136 6.7E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.6E-13 T 29-03-2018 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 1.6E-13 T 29-03-2018 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.6E-13 T 29-03-2018 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.6E-13 T 29-03-2018 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 141 165 2.4E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 34 49 2.4E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 55 65 2.4E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 138 2.4E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 2.4E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 2.4E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 Gene3D G3DSA:3.50.50.60 144 300 9.0E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS15325 295f405aaa0bbb1ee390ef04d2ff87cc 305 SUPERFAMILY SSF51905 1 300 5.01E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS12730 f5fcb5f67da8ba16d807e2a62ef7d33f 161 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 12 128 1.9E-10 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CB4_RS12730 f5fcb5f67da8ba16d807e2a62ef7d33f 161 Gene3D G3DSA:3.30.530.20 1 142 3.6E-17 T 29-03-2018 IPR023393 START-like domain CB4_RS12730 f5fcb5f67da8ba16d807e2a62ef7d33f 161 SUPERFAMILY SSF55961 1 145 9.78E-19 T 29-03-2018 CB4_RS16415 c67f3d4cd988acd2cf1afab617c21711 126 SMART SM00450 29 125 7.2E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS16415 c67f3d4cd988acd2cf1afab617c21711 126 Pfam PF00581 Rhodanese-like domain 30 120 1.7E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS16415 c67f3d4cd988acd2cf1afab617c21711 126 SUPERFAMILY SSF52821 7 121 7.46E-33 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS16415 c67f3d4cd988acd2cf1afab617c21711 126 Gene3D G3DSA:3.40.250.10 22 124 1.1E-28 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 Gene3D G3DSA:2.30.330.10 238 330 1.2E-15 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 SUPERFAMILY SSF101801 254 326 9.16E-13 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 323 2.4E-111 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 PIRSF PIRSF002888 1 332 6.4E-114 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 Gene3D G3DSA:3.40.1550.10 47 236 1.3E-52 T 29-03-2018 IPR028976 CheC-like domain CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 Pfam PF02154 Flagellar motor switch protein FliM 39 229 2.9E-73 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 SUPERFAMILY SSF103039 46 230 1.83E-31 T 29-03-2018 IPR028976 CheC-like domain CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 3.2E-28 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 3.2E-28 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 3.2E-28 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 3.2E-28 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CB4_RS09150 3c2cd7174e31b05086782be137a0f297 332 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 253 322 6.7E-16 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CB4_RS20355 c8e890d9bbe50bc796b8804a2eb6c054 201 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 2 188 32.208 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CB4_RS20355 c8e890d9bbe50bc796b8804a2eb6c054 201 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 1 191 1.9E-71 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CB4_RS20355 c8e890d9bbe50bc796b8804a2eb6c054 201 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS20355 c8e890d9bbe50bc796b8804a2eb6c054 201 SUPERFAMILY SSF53328 1 196 8.5E-63 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS20355 c8e890d9bbe50bc796b8804a2eb6c054 201 Gene3D G3DSA:3.40.50.170 1 201 6.2E-65 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS20355 c8e890d9bbe50bc796b8804a2eb6c054 201 Pfam PF00551 Formyl transferase 1 182 1.4E-59 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CB4_RS15165 538f241cfcee4caff3d99e3987c1fdaa 284 Gene3D G3DSA:3.40.190.10 130 262 1.2E-27 T 29-03-2018 CB4_RS15165 538f241cfcee4caff3d99e3987c1fdaa 284 Gene3D G3DSA:3.40.190.10 1 129 4.1E-14 T 29-03-2018 CB4_RS15165 538f241cfcee4caff3d99e3987c1fdaa 284 SUPERFAMILY SSF53850 4 267 5.21E-76 T 29-03-2018 CB4_RS15165 538f241cfcee4caff3d99e3987c1fdaa 284 Pfam PF02621 Menaquinone biosynthesis 4 261 4.9E-64 T 29-03-2018 IPR003773 Menaquinone biosynthesis enzyme CB4_RS15165 538f241cfcee4caff3d99e3987c1fdaa 284 Hamap MF_00995 Chorismate dehydratase [mqnA]. 5 266 29.145 T 29-03-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 CB4_RS16280 94df79f170341d36ddb7668168a3dfa6 275 SUPERFAMILY SSF53167 5 274 3.01E-91 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CB4_RS16280 94df79f170341d36ddb7668168a3dfa6 275 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 25 271 4.9E-102 T 29-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CB4_RS16280 94df79f170341d36ddb7668168a3dfa6 275 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 25 271 3.9E-100 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CB4_RS16280 94df79f170341d36ddb7668168a3dfa6 275 PIRSF PIRSF000477 1 274 5.0E-106 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CB4_RS16280 94df79f170341d36ddb7668168a3dfa6 275 Gene3D G3DSA:3.40.50.1580 1 274 4.5E-73 T 29-03-2018 CB4_RS16280 94df79f170341d36ddb7668168a3dfa6 275 Pfam PF01048 Phosphorylase superfamily 26 270 2.4E-49 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CB4_RS00565 290f74297edbed6057bb380bf43281fd 564 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 178 2.7E-29 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS00565 290f74297edbed6057bb380bf43281fd 564 Pfam PF00672 HAMP domain 205 254 7.7E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS00565 290f74297edbed6057bb380bf43281fd 564 Gene3D G3DSA:1.10.287.950 317 564 2.5E-53 T 29-03-2018 CB4_RS00565 290f74297edbed6057bb380bf43281fd 564 SMART SM00283 287 562 2.7E-66 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS00565 290f74297edbed6057bb380bf43281fd 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 334 513 6.4E-42 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS00565 290f74297edbed6057bb380bf43281fd 564 Gene3D G3DSA:1.20.120.30 19 179 1.2E-19 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CB4_RS00565 290f74297edbed6057bb380bf43281fd 564 SMART SM00304 205 258 6.3E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS00565 290f74297edbed6057bb380bf43281fd 564 SUPERFAMILY SSF58104 231 260 8.11E-68 T 29-03-2018 CB4_RS00565 290f74297edbed6057bb380bf43281fd 564 SUPERFAMILY SSF58104 293 562 8.11E-68 T 29-03-2018 CB4_RS00565 290f74297edbed6057bb380bf43281fd 564 Gene3D G3DSA:1.10.287.850 229 316 5.8E-4 T 29-03-2018 CB4_RS14990 85832c1c151c85f76d86e74e363d67e4 238 SUPERFAMILY SSF102588 9 235 3.01E-55 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CB4_RS14990 85832c1c151c85f76d86e74e363d67e4 238 Pfam PF02585 GlcNAc-PI de-N-acetylase 12 129 2.8E-19 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CB4_RS14990 85832c1c151c85f76d86e74e363d67e4 238 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 9 233 3.0E-87 T 29-03-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 CB4_RS14990 85832c1c151c85f76d86e74e363d67e4 238 Gene3D G3DSA:3.40.50.10320 7 235 1.4E-50 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 660 762 9.4E-10 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 Gene3D G3DSA:3.30.230.10 554 789 1.8E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 576 592 1.2E-17 T 29-03-2018 CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 71 90 1.2E-17 T 29-03-2018 CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 657 676 1.2E-17 T 29-03-2018 CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 717 735 1.2E-17 T 29-03-2018 CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 687 706 1.2E-17 T 29-03-2018 CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 Gene3D G3DSA:3.40.50.300 39 457 1.1E-8 T 29-03-2018 CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 Pfam PF13654 AAA domain 34 550 1.4E-192 T 29-03-2018 CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 SUPERFAMILY SSF52540 59 173 2.22E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 SUPERFAMILY SSF52540 317 561 4.16E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 SUPERFAMILY SSF52540 42 100 4.16E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03580 ff09a4485596f69038c59cd270f1a665 824 SUPERFAMILY SSF54211 574 768 1.25E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS16140 af308e2f052079b7f4a6ff0a321bbecf 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 289 8.2E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS16140 af308e2f052079b7f4a6ff0a321bbecf 300 SUPERFAMILY SSF161098 27 289 8.78E-53 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS16140 af308e2f052079b7f4a6ff0a321bbecf 300 Gene3D G3DSA:1.10.3720.10 27 293 3.9E-43 T 29-03-2018 CB4_RS19640 34c63291fb73311732a5cbcd2b5c3e9c 182 Pfam PF08747 Domain of unknown function (DUF1788) 62 181 4.7E-33 T 29-03-2018 IPR014858 Protein of unknown function DUF1788 CB4_RS19750 902e229e3e646c1cb6382e057487fafc 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 20 359 1.6E-144 T 29-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CB4_RS19750 902e229e3e646c1cb6382e057487fafc 371 SUPERFAMILY SSF52518 36 361 6.08E-110 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS19750 902e229e3e646c1cb6382e057487fafc 371 Pfam PF00676 Dehydrogenase E1 component 48 337 4.9E-96 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CB4_RS19750 902e229e3e646c1cb6382e057487fafc 371 Gene3D G3DSA:3.40.50.970 8 360 1.1E-97 T 29-03-2018 CB4_RS06315 2c9023e7991faf82cec4f73d0f1bb6d8 311 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 5 76 1.2E-18 T 29-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 CB4_RS13005 460fb0b3799358f8be6ac69f34f50f5f 211 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 75 160 5.2E-17 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CB4_RS13005 460fb0b3799358f8be6ac69f34f50f5f 211 SUPERFAMILY SSF51230 41 112 1.33E-8 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS13005 460fb0b3799358f8be6ac69f34f50f5f 211 Gene3D G3DSA:1.20.1600.10 94 192 2.7E-11 T 29-03-2018 CB4_RS13005 460fb0b3799358f8be6ac69f34f50f5f 211 Gene3D G3DSA:2.40.50.100 24 93 0.0012 T 29-03-2018 CB4_RS09560 5715c008437636375c1bc417786a555b 1006 SUPERFAMILY SSF50370 485 610 4.46E-19 T 29-03-2018 IPR000772 Ricin B, lectin domain CB4_RS09560 5715c008437636375c1bc417786a555b 1006 Gene3D G3DSA:2.80.10.50 277 433 5.8E-7 T 29-03-2018 CB4_RS09560 5715c008437636375c1bc417786a555b 1006 Gene3D G3DSA:2.80.10.50 530 641 7.1E-10 T 29-03-2018 CB4_RS09560 5715c008437636375c1bc417786a555b 1006 Gene3D G3DSA:2.80.10.50 434 529 3.7E-11 T 29-03-2018 CB4_RS09560 5715c008437636375c1bc417786a555b 1006 Gene3D G3DSA:2.60.120.200 16 223 2.2E-35 T 29-03-2018 CB4_RS09560 5715c008437636375c1bc417786a555b 1006 SMART SM00282 44 178 3.8E-5 T 29-03-2018 IPR001791 Laminin G domain CB4_RS09560 5715c008437636375c1bc417786a555b 1006 Gene3D G3DSA:2.60.60.20 642 795 2.1E-16 T 29-03-2018 IPR001024 PLAT/LH2 domain GO:0005515 CB4_RS09560 5715c008437636375c1bc417786a555b 1006 SUPERFAMILY SSF50370 399 528 3.63E-17 T 29-03-2018 IPR000772 Ricin B, lectin domain CB4_RS09560 5715c008437636375c1bc417786a555b 1006 Pfam PF00652 Ricin-type beta-trefoil lectin domain 491 610 2.2E-7 T 29-03-2018 IPR000772 Ricin B, lectin domain CB4_RS09560 5715c008437636375c1bc417786a555b 1006 Pfam PF00652 Ricin-type beta-trefoil lectin domain 360 480 9.3E-7 T 29-03-2018 IPR000772 Ricin B, lectin domain CB4_RS09560 5715c008437636375c1bc417786a555b 1006 SMART SM00458 484 613 0.057 T 29-03-2018 IPR000772 Ricin B, lectin domain CB4_RS09560 5715c008437636375c1bc417786a555b 1006 SMART SM00458 356 483 2.0 T 29-03-2018 IPR000772 Ricin B, lectin domain CB4_RS09560 5715c008437636375c1bc417786a555b 1006 SMART SM00308 638 755 6.2E-4 T 29-03-2018 IPR001024 PLAT/LH2 domain GO:0005515 CB4_RS09560 5715c008437636375c1bc417786a555b 1006 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 40 184 5.4E-22 T 29-03-2018 CB4_RS09560 5715c008437636375c1bc417786a555b 1006 Pfam PF01477 PLAT/LH2 domain 642 729 4.3E-14 T 29-03-2018 IPR001024 PLAT/LH2 domain GO:0005515 CB4_RS09560 5715c008437636375c1bc417786a555b 1006 SUPERFAMILY SSF49723 637 742 3.08E-18 T 29-03-2018 IPR001024 PLAT/LH2 domain GO:0005515 CB4_RS09560 5715c008437636375c1bc417786a555b 1006 SUPERFAMILY SSF49899 19 209 2.14E-30 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CB4_RS08705 5d5d45a934351ec28204f84e70189cf5 252 SUPERFAMILY SSF53098 59 247 1.2E-63 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS08705 5d5d45a934351ec28204f84e70189cf5 252 Gene3D G3DSA:3.30.420.10 46 250 3.3E-62 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS08705 5d5d45a934351ec28204f84e70189cf5 252 Hamap MF_00052_B Ribonuclease HII [rnhB]. 70 249 34.884 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 CB4_RS08705 5d5d45a934351ec28204f84e70189cf5 252 Pfam PF01351 Ribonuclease HII 72 246 1.1E-32 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain CB4_RS13975 388a3f8028dea0fc1740466d2a8a14d5 368 Gene3D G3DSA:3.20.20.150 1 291 4.0E-53 T 29-03-2018 CB4_RS13975 388a3f8028dea0fc1740466d2a8a14d5 368 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 210 226 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CB4_RS13975 388a3f8028dea0fc1740466d2a8a14d5 368 Hamap MF_00152 Probable endonuclease 4 [nfo]. 1 282 39.591 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CB4_RS13975 388a3f8028dea0fc1740466d2a8a14d5 368 SMART SM00518 2 282 7.7E-113 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CB4_RS13975 388a3f8028dea0fc1740466d2a8a14d5 368 SUPERFAMILY SSF51658 1 283 3.27E-91 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CB4_RS13975 388a3f8028dea0fc1740466d2a8a14d5 368 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 2 278 6.2E-92 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CB4_RS13975 388a3f8028dea0fc1740466d2a8a14d5 368 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 172 179 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CB4_RS13975 388a3f8028dea0fc1740466d2a8a14d5 368 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 67 75 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CB4_RS13975 388a3f8028dea0fc1740466d2a8a14d5 368 Pfam PF01261 Xylose isomerase-like TIM barrel 21 233 2.2E-35 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CB4_RS04820 6fdfd6dd7adc1f47ac61dac95a8c6415 148 SUPERFAMILY SSF54001 27 147 1.59E-42 T 29-03-2018 CB4_RS04820 6fdfd6dd7adc1f47ac61dac95a8c6415 148 Gene3D G3DSA:2.30.260.10 74 147 3.3E-24 T 29-03-2018 CB4_RS04820 6fdfd6dd7adc1f47ac61dac95a8c6415 148 Gene3D G3DSA:3.90.1720.10 19 73 1.1E-14 T 29-03-2018 CB4_RS04820 6fdfd6dd7adc1f47ac61dac95a8c6415 148 Pfam PF00877 NlpC/P60 family 40 146 4.5E-31 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CB4_RS17225 b84718d208fa9c62a3c72c48796caa28 328 SUPERFAMILY SSF56281 17 323 1.9E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS17225 b84718d208fa9c62a3c72c48796caa28 328 Gene3D G3DSA:3.60.15.10 5 260 1.9E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS17225 b84718d208fa9c62a3c72c48796caa28 328 Gene3D G3DSA:1.10.10.10 261 324 8.3E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS17225 b84718d208fa9c62a3c72c48796caa28 328 SMART SM00849 23 240 8.6E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS17225 b84718d208fa9c62a3c72c48796caa28 328 Pfam PF00753 Metallo-beta-lactamase superfamily 21 240 3.5E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS00795 b80f55132a8218d7defec38f4e8a4a62 257 Gene3D G3DSA:3.30.70.660 108 254 4.6E-39 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS00795 b80f55132a8218d7defec38f4e8a4a62 257 Gene3D G3DSA:3.30.70.580 1 107 2.6E-30 T 29-03-2018 CB4_RS00795 b80f55132a8218d7defec38f4e8a4a62 257 Pfam PF01416 tRNA pseudouridine synthase 11 106 2.5E-7 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS00795 b80f55132a8218d7defec38f4e8a4a62 257 Pfam PF01416 tRNA pseudouridine synthase 145 255 5.7E-30 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS00795 b80f55132a8218d7defec38f4e8a4a62 257 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 4 250 1.1E-56 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS00795 b80f55132a8218d7defec38f4e8a4a62 257 PIRSF PIRSF001430 3 257 4.7E-78 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS00795 b80f55132a8218d7defec38f4e8a4a62 257 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 4 255 34.078 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS00795 b80f55132a8218d7defec38f4e8a4a62 257 SUPERFAMILY SSF55120 4 256 5.47E-80 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS19185 3c44dfbbc1586307c3016eb757476383 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 426 1.9E-170 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CB4_RS19185 3c44dfbbc1586307c3016eb757476383 429 Pfam PF00202 Aminotransferase class-III 36 399 5.5E-73 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CB4_RS19185 3c44dfbbc1586307c3016eb757476383 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 93.839 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CB4_RS19185 3c44dfbbc1586307c3016eb757476383 429 Gene3D G3DSA:3.90.1150.10 315 429 3.4E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS19185 3c44dfbbc1586307c3016eb757476383 429 Gene3D G3DSA:3.90.1150.10 1 168 4.0E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS19185 3c44dfbbc1586307c3016eb757476383 429 SUPERFAMILY SSF53383 1 424 2.07E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS19185 3c44dfbbc1586307c3016eb757476383 429 Gene3D G3DSA:3.40.640.10 169 314 5.4E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS01725 b5e85a7a019ad8f01dcd71cd78c6e42e 286 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 7.5E-33 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS01725 b5e85a7a019ad8f01dcd71cd78c6e42e 286 Gene3D G3DSA:3.40.50.720 1 184 8.0E-52 T 29-03-2018 CB4_RS01725 b5e85a7a019ad8f01dcd71cd78c6e42e 286 Gene3D G3DSA:1.10.1040.10 185 286 7.9E-33 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CB4_RS01725 b5e85a7a019ad8f01dcd71cd78c6e42e 286 PIRSF PIRSF000105 1 286 2.7E-86 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CB4_RS01725 b5e85a7a019ad8f01dcd71cd78c6e42e 286 SUPERFAMILY SSF48179 186 285 1.28E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS01725 b5e85a7a019ad8f01dcd71cd78c6e42e 286 SUPERFAMILY SSF51735 2 183 1.49E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS01725 b5e85a7a019ad8f01dcd71cd78c6e42e 286 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 182 1.1E-59 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS03210 c15e7dc01a2c72da4f080a60f11d0b52 289 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 287 7.9E-156 T 29-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CB4_RS03210 c15e7dc01a2c72da4f080a60f11d0b52 289 SUPERFAMILY SSF53448 2 286 1.53E-94 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS03210 c15e7dc01a2c72da4f080a60f11d0b52 289 Pfam PF00483 Nucleotidyl transferase 2 237 4.4E-74 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CB4_RS03210 c15e7dc01a2c72da4f080a60f11d0b52 289 Gene3D G3DSA:3.90.550.10 1 289 2.7E-71 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS13545 cb45358895a9aabacbce84ccdee96981 202 Gene3D G3DSA:3.90.1720.10 80 202 1.5E-32 T 29-03-2018 CB4_RS13545 cb45358895a9aabacbce84ccdee96981 202 Pfam PF00877 NlpC/P60 family 95 199 8.4E-24 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CB4_RS13545 cb45358895a9aabacbce84ccdee96981 202 SUPERFAMILY SSF54001 78 201 2.35E-34 T 29-03-2018 CB4_RS17060 3369377fb7866773cfc6f67f5122b86e 160 Pfam PF09712 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) 13 91 5.6E-6 T 29-03-2018 IPR010123 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit CB4_RS17060 3369377fb7866773cfc6f67f5122b86e 160 Gene3D G3DSA:1.20.5.320 49 158 1.4E-4 T 29-03-2018 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 24 354 63.15 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 27 40 3.6E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 99 119 3.6E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 153 165 3.6E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 286 295 3.6E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 176 197 3.6E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 120 139 3.6E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 Pfam PF00814 Glycoprotease family 46 329 5.9E-104 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 27 329 1.2E-108 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 SUPERFAMILY SSF53067 25 330 2.59E-41 T 29-03-2018 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 Gene3D G3DSA:3.30.420.40 167 312 3.2E-18 T 29-03-2018 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 26 336 1.3E-134 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CB4_RS20475 387f8400f9ddab065a7cb13635435a8a 355 Gene3D G3DSA:3.30.420.40 24 166 1.0E-45 T 29-03-2018 CB4_RS15500 6db0718797dbdf22db01f16221daefeb 412 Gene3D G3DSA:3.30.2400.10 152 301 2.5E-27 T 29-03-2018 CB4_RS15500 6db0718797dbdf22db01f16221daefeb 412 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 5 411 3.8E-90 T 29-03-2018 IPR024455 Phage capsid CB4_RS15500 6db0718797dbdf22db01f16221daefeb 412 Pfam PF05065 Phage capsid family 133 411 3.5E-58 T 29-03-2018 IPR024455 Phage capsid CB4_RS15500 6db0718797dbdf22db01f16221daefeb 412 SUPERFAMILY SSF56563 123 411 1.57E-57 T 29-03-2018 CB4_RS13505 63af240fad0e21de658ae797c622813e 463 SUPERFAMILY SSF47384 224 305 2.94E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13505 63af240fad0e21de658ae797c622813e 463 SMART SM00304 185 239 5.0E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS13505 63af240fad0e21de658ae797c622813e 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 7.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13505 63af240fad0e21de658ae797c622813e 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 7.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13505 63af240fad0e21de658ae797c622813e 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 7.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13505 63af240fad0e21de658ae797c622813e 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 7.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS13505 63af240fad0e21de658ae797c622813e 463 SMART SM00388 240 307 1.2E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13505 63af240fad0e21de658ae797c622813e 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 305 1.7E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CB4_RS13505 63af240fad0e21de658ae797c622813e 463 Gene3D G3DSA:1.10.287.130 230 294 4.3E-17 T 29-03-2018 CB4_RS13505 63af240fad0e21de658ae797c622813e 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 456 7.4E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13505 63af240fad0e21de658ae797c622813e 463 SMART SM00387 348 460 3.9E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13505 63af240fad0e21de658ae797c622813e 463 Gene3D G3DSA:3.30.565.10 295 463 6.0E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13505 63af240fad0e21de658ae797c622813e 463 SUPERFAMILY SSF55874 297 456 5.89E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS09110 c8c9e875edde7e055e3131e0866daa00 148 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 140 7.6E-19 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CB4_RS09110 c8c9e875edde7e055e3131e0866daa00 148 Pfam PF02050 Flagellar FliJ protein 19 140 1.4E-12 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CB4_RS08670 9777fcb155d709d9a3c7b7893e3f909f 75 Pfam PF13083 KH domain 2 74 6.0E-23 T 29-03-2018 CB4_RS08670 9777fcb155d709d9a3c7b7893e3f909f 75 Hamap MF_00088 UPF0109 protein . 1 75 21.929 T 29-03-2018 IPR020627 Uncharacterised protein family UPF0109 CB4_RS08670 9777fcb155d709d9a3c7b7893e3f909f 75 Gene3D G3DSA:3.30.300.20 1 75 1.2E-15 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CB4_RS08670 9777fcb155d709d9a3c7b7893e3f909f 75 SUPERFAMILY SSF54814 6 62 1.83E-9 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CB4_RS12490 490b11fd6ff6a672186f37a3d0a96ba0 233 SUPERFAMILY SSF52540 7 226 2.35E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS12490 490b11fd6ff6a672186f37a3d0a96ba0 233 Pfam PF00005 ABC transporter 24 173 8.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS12490 490b11fd6ff6a672186f37a3d0a96ba0 233 Gene3D G3DSA:3.40.50.300 1 230 2.1E-65 T 29-03-2018 CB4_RS12490 490b11fd6ff6a672186f37a3d0a96ba0 233 SMART SM00382 33 221 1.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS12490 490b11fd6ff6a672186f37a3d0a96ba0 233 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS10955 9020fe3d3975dbcc91dd44d6012fba28 115 SMART SM00418 10 87 4.5E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS10955 9020fe3d3975dbcc91dd44d6012fba28 115 Gene3D G3DSA:1.10.10.10 1 80 6.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS10955 9020fe3d3975dbcc91dd44d6012fba28 115 SUPERFAMILY SSF46785 2 87 7.87E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS10955 9020fe3d3975dbcc91dd44d6012fba28 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 6.6E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS10955 9020fe3d3975dbcc91dd44d6012fba28 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 6.6E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS10955 9020fe3d3975dbcc91dd44d6012fba28 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 42 6.6E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS10955 9020fe3d3975dbcc91dd44d6012fba28 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 6.6E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS10955 9020fe3d3975dbcc91dd44d6012fba28 115 Pfam PF01022 Bacterial regulatory protein, arsR family 17 62 2.8E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS07350 cbdb4c77cf1c681c400dddbe78130c66 278 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 32 263 1.7E-37 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 CB4_RS07350 cbdb4c77cf1c681c400dddbe78130c66 278 Pfam PF09323 Domain of unknown function (DUF1980) 16 112 4.9E-8 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 CB4_RS04730 f287e84af505c5f3fe2d942214280dd7 466 Pfam PF01458 Uncharacterized protein family (UPF0051) 212 437 3.0E-71 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CB4_RS04730 f287e84af505c5f3fe2d942214280dd7 466 SUPERFAMILY SSF101960 33 463 1.19E-136 T 29-03-2018 CB4_RS04730 f287e84af505c5f3fe2d942214280dd7 466 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 11 457 1.6E-224 T 29-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CB4_RS01760 9947338b733e5e3989c68ebbf9e81785 462 SUPERFAMILY SSF52540 6 199 5.73E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01760 9947338b733e5e3989c68ebbf9e81785 462 Gene3D G3DSA:3.40.50.300 2 181 1.4E-39 T 29-03-2018 CB4_RS01760 9947338b733e5e3989c68ebbf9e81785 462 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 249 439 1.1E-37 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CB4_RS01760 9947338b733e5e3989c68ebbf9e81785 462 SUPERFAMILY SSF52317 245 453 9.01E-33 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS01760 9947338b733e5e3989c68ebbf9e81785 462 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 8 194 1.0E-19 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CB4_RS01760 9947338b733e5e3989c68ebbf9e81785 462 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 7 448 4.9E-141 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CB4_RS01760 9947338b733e5e3989c68ebbf9e81785 462 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 5 440 45.161 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CB4_RS01760 9947338b733e5e3989c68ebbf9e81785 462 Gene3D G3DSA:3.40.50.880 236 461 4.6E-22 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CB4_RS10160 5e4a772e2d4a671403773bb5c2abf165 294 SUPERFAMILY SSF56784 3 283 9.6E-70 T 29-03-2018 IPR023214 HAD-like domain CB4_RS10160 5e4a772e2d4a671403773bb5c2abf165 294 Gene3D G3DSA:3.40.50.1000 1 287 2.1E-39 T 29-03-2018 IPR023214 HAD-like domain CB4_RS10160 5e4a772e2d4a671403773bb5c2abf165 294 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 252 1.5E-25 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CB4_RS10160 5e4a772e2d4a671403773bb5c2abf165 294 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 279 1.5E-64 T 29-03-2018 IPR000150 Cof family GO:0016787 CB4_RS10160 5e4a772e2d4a671403773bb5c2abf165 294 ProSitePatterns PS01229 Hypothetical cof family signature 2. 233 255 - T 29-03-2018 CB4_RS10160 5e4a772e2d4a671403773bb5c2abf165 294 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 29-03-2018 CB4_RS10160 5e4a772e2d4a671403773bb5c2abf165 294 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 279 1.6E-68 T 29-03-2018 IPR023214 HAD-like domain CB4_RS04265 07e868648ad638b7da29c2d886feb1f1 213 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 2 202 2.0E-73 T 29-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 CB4_RS04265 07e868648ad638b7da29c2d886feb1f1 213 SUPERFAMILY SSF55469 10 211 1.57E-47 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS04265 07e868648ad638b7da29c2d886feb1f1 213 Gene3D G3DSA:3.40.109.10 2 213 9.5E-43 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS04265 07e868648ad638b7da29c2d886feb1f1 213 Pfam PF00881 Nitroreductase family 14 180 2.3E-27 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CB4_RS05920 bcb3f9cd9ab2e499f4187e25571f651a 529 SMART SM00257 3 48 1.1E-14 T 29-03-2018 IPR018392 LysM domain CB4_RS05920 bcb3f9cd9ab2e499f4187e25571f651a 529 Gene3D G3DSA:3.10.350.10 1 74 2.0E-14 T 29-03-2018 CB4_RS05920 bcb3f9cd9ab2e499f4187e25571f651a 529 SUPERFAMILY SSF54106 2 48 4.58E-10 T 29-03-2018 IPR018392 LysM domain CB4_RS05920 bcb3f9cd9ab2e499f4187e25571f651a 529 Pfam PF01476 LysM domain 4 48 1.4E-13 T 29-03-2018 IPR018392 LysM domain CB4_RS05920 bcb3f9cd9ab2e499f4187e25571f651a 529 PRINTS PR01217 Proline rich extensin signature 167 183 1.5E-9 T 29-03-2018 CB4_RS05920 bcb3f9cd9ab2e499f4187e25571f651a 529 PRINTS PR01217 Proline rich extensin signature 126 138 1.5E-9 T 29-03-2018 CB4_RS05920 bcb3f9cd9ab2e499f4187e25571f651a 529 PRINTS PR01217 Proline rich extensin signature 210 235 1.5E-9 T 29-03-2018 CB4_RS05920 bcb3f9cd9ab2e499f4187e25571f651a 529 PRINTS PR01217 Proline rich extensin signature 104 120 1.5E-9 T 29-03-2018 CB4_RS05920 bcb3f9cd9ab2e499f4187e25571f651a 529 PRINTS PR01217 Proline rich extensin signature 145 166 1.5E-9 T 29-03-2018 CB4_RS05965 a25777fbdd7304811b0893bda3a6f685 103 PRINTS PR01853 Bacterial YajC preprotein translocase signature 43 61 2.1E-14 T 29-03-2018 IPR003849 Preprotein translocase YajC CB4_RS05965 a25777fbdd7304811b0893bda3a6f685 103 PRINTS PR01853 Bacterial YajC preprotein translocase signature 5 25 2.1E-14 T 29-03-2018 IPR003849 Preprotein translocase YajC CB4_RS05965 a25777fbdd7304811b0893bda3a6f685 103 Pfam PF02699 Preprotein translocase subunit 7 83 9.6E-27 T 29-03-2018 IPR003849 Preprotein translocase YajC CB4_RS05965 a25777fbdd7304811b0893bda3a6f685 103 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 6 85 3.4E-25 T 29-03-2018 IPR003849 Preprotein translocase YajC CB4_RS05965 a25777fbdd7304811b0893bda3a6f685 103 SMART SM01323 3 86 6.4E-34 T 29-03-2018 IPR003849 Preprotein translocase YajC CB4_RS20505 d7ab69cfd8b23b93f813f0c34880ce64 338 SUPERFAMILY SSF56042 154 319 2.24E-31 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20505 d7ab69cfd8b23b93f813f0c34880ce64 338 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 6 337 5.5E-94 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CB4_RS20505 d7ab69cfd8b23b93f813f0c34880ce64 338 PIRSF PIRSF005303 1 337 6.9E-93 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CB4_RS20505 d7ab69cfd8b23b93f813f0c34880ce64 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 160 315 2.5E-11 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS20505 d7ab69cfd8b23b93f813f0c34880ce64 338 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 4 334 28.737 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CB4_RS20505 d7ab69cfd8b23b93f813f0c34880ce64 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 148 6.9E-21 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20505 d7ab69cfd8b23b93f813f0c34880ce64 338 Gene3D G3DSA:3.30.1330.10 14 154 1.5E-29 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20505 d7ab69cfd8b23b93f813f0c34880ce64 338 SUPERFAMILY SSF55326 9 149 1.26E-32 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CB4_RS20505 d7ab69cfd8b23b93f813f0c34880ce64 338 Gene3D G3DSA:3.90.650.10 155 337 4.2E-39 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 Gene3D G3DSA:1.10.1040.10 369 467 2.0E-10 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 Pfam PF00378 Enoyl-CoA hydratase/isomerase 493 629 3.1E-11 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 SUPERFAMILY SSF51735 4 206 3.29E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 SUPERFAMILY SSF52096 488 798 6.44E-40 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 SUPERFAMILY SSF48179 362 448 3.15E-15 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 SUPERFAMILY SSF48179 206 312 5.87E-21 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 Gene3D G3DSA:1.10.1040.10 206 313 4.6E-19 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 Gene3D G3DSA:3.40.50.720 1 205 3.1E-39 T 29-03-2018 CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 205 7.7E-43 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 Gene3D G3DSA:3.90.226.10 481 799 7.1E-41 T 29-03-2018 CB4_RS10405 96226002c6a1f6faa18bac7ec34ac29e 801 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 208 307 7.2E-14 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS17465 77cef21e63f5c11a39f5358715832892 189 Gene3D G3DSA:3.40.109.10 2 187 2.7E-38 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS17465 77cef21e63f5c11a39f5358715832892 189 Pfam PF00881 Nitroreductase family 8 167 4.0E-31 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CB4_RS17465 77cef21e63f5c11a39f5358715832892 189 PIRSF PIRSF000232 1 189 5.7E-52 T 29-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like CB4_RS17465 77cef21e63f5c11a39f5358715832892 189 SUPERFAMILY SSF55469 2 186 4.06E-42 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 Gene3D G3DSA:3.40.50.720 197 430 1.7E-73 T 29-03-2018 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 116 129 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 PIRSF PIRSF000185 18 430 7.1E-170 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 197 428 7.2E-75 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 SMART SM00839 199 428 7.1E-92 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 51 179 3.4E-55 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 SUPERFAMILY SSF51735 197 429 1.1E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 Gene3D G3DSA:3.40.50.10860 49 183 7.9E-52 T 29-03-2018 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 SUPERFAMILY SSF53223 21 199 4.48E-66 T 29-03-2018 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 230 250 1.4E-29 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 356 367 1.4E-29 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 188 210 1.4E-29 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS15300 14924db0fcc08d638dce89724a92df32 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 108 122 1.4E-29 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CB4_RS19580 88b66aa178f3b67cb7995a16c88c698d 255 Gene3D G3DSA:3.40.1350.10 2 163 5.7E-39 T 29-03-2018 CB4_RS19580 88b66aa178f3b67cb7995a16c88c698d 255 Gene3D G3DSA:1.10.10.10 167 255 1.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19580 88b66aa178f3b67cb7995a16c88c698d 255 Pfam PF08722 TnsA endonuclease N terminal 64 160 6.5E-15 T 29-03-2018 IPR014833 TnsA endonuclease, N-terminal CB4_RS19580 88b66aa178f3b67cb7995a16c88c698d 255 SUPERFAMILY SSF52980 3 163 3.11E-48 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CB4_RS19580 88b66aa178f3b67cb7995a16c88c698d 255 Pfam PF08721 TnsA endonuclease C terminal 163 240 2.8E-13 T 29-03-2018 IPR014832 TnsA endonuclease C-terminal CB4_RS06745 7b91995ccef9aebf3cc39ced8a2f62ad 304 SUPERFAMILY SSF56112 15 285 5.4E-49 T 29-03-2018 IPR011009 Protein kinase-like domain CB4_RS06745 7b91995ccef9aebf3cc39ced8a2f62ad 304 Gene3D G3DSA:1.10.510.10 107 280 2.4E-38 T 29-03-2018 CB4_RS06745 7b91995ccef9aebf3cc39ced8a2f62ad 304 SMART SM00220 20 289 1.9E-24 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CB4_RS06745 7b91995ccef9aebf3cc39ced8a2f62ad 304 Pfam PF00069 Protein kinase domain 76 242 4.9E-35 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CB4_RS06745 7b91995ccef9aebf3cc39ced8a2f62ad 304 Gene3D G3DSA:3.30.200.20 9 106 9.2E-16 T 29-03-2018 CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 151 5.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 106 122 5.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 207 5.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 170 5.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 59 70 5.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 SUPERFAMILY SSF51735 1 223 5.67E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 2 218 5.6E-48 T 29-03-2018 CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 151 1.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 59 70 1.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 112 120 1.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 119 147 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CB4_RS14845 eaf741b985754bea5d4661cb067c97d5 225 Gene3D G3DSA:3.40.50.720 3 225 1.2E-55 T 29-03-2018 CB4_RS16100 8eb90de4a238dbc64dd3fe7a1aa9c240 389 PIRSF PIRSF038994 2 388 4.1E-139 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CB4_RS16100 8eb90de4a238dbc64dd3fe7a1aa9c240 389 Pfam PF01979 Amidohydrolase family 54 384 2.9E-32 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CB4_RS16100 8eb90de4a238dbc64dd3fe7a1aa9c240 389 SUPERFAMILY SSF51556 57 356 1.42E-102 T 29-03-2018 IPR032466 Metal-dependent hydrolase CB4_RS16100 8eb90de4a238dbc64dd3fe7a1aa9c240 389 Gene3D G3DSA:2.30.40.10 4 71 2.9E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS16100 8eb90de4a238dbc64dd3fe7a1aa9c240 389 SUPERFAMILY SSF51338 356 386 1.56E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS16100 8eb90de4a238dbc64dd3fe7a1aa9c240 389 SUPERFAMILY SSF51338 4 56 1.56E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CB4_RS16100 8eb90de4a238dbc64dd3fe7a1aa9c240 389 Gene3D G3DSA:3.20.20.140 72 356 4.3E-113 T 29-03-2018 CB4_RS16100 8eb90de4a238dbc64dd3fe7a1aa9c240 389 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 4 382 6.6E-124 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CB4_RS17410 55e9db4de62dabd7b9dadc4e518f31b2 385 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 8 365 2.7E-115 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CB4_RS17410 55e9db4de62dabd7b9dadc4e518f31b2 385 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 324 348 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CB4_RS17410 55e9db4de62dabd7b9dadc4e518f31b2 385 Pfam PF01098 Cell cycle protein 11 367 2.2E-109 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CB4_RS20485 ffc5191d91f56837daf68609c0cfaac1 196 SMART SM00283 1 194 2.1E-37 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS20485 ffc5191d91f56837daf68609c0cfaac1 196 SUPERFAMILY SSF58104 2 194 2.09E-57 T 29-03-2018 CB4_RS20485 ffc5191d91f56837daf68609c0cfaac1 196 Gene3D G3DSA:1.10.287.950 1 196 3.8E-54 T 29-03-2018 CB4_RS20485 ffc5191d91f56837daf68609c0cfaac1 196 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 46 75 1.3E-19 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS20485 ffc5191d91f56837daf68609c0cfaac1 196 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 17 44 1.3E-19 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CB4_RS20485 ffc5191d91f56837daf68609c0cfaac1 196 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 1 147 3.3E-48 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS18095 65de56861c2bc29e7e71dee0a5caaaab 275 Pfam PF08223 PaaX-like protein C-terminal domain 168 265 2.8E-31 T 29-03-2018 IPR013225 PaaX-like, C-terminal CB4_RS18095 65de56861c2bc29e7e71dee0a5caaaab 275 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 5 268 4.2E-88 T 29-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CB4_RS18095 65de56861c2bc29e7e71dee0a5caaaab 275 PIRSF PIRSF020623 1 275 3.0E-99 T 29-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CB4_RS18095 65de56861c2bc29e7e71dee0a5caaaab 275 Pfam PF07848 PaaX-like protein 3 71 2.1E-25 T 29-03-2018 IPR012906 PaaX-like, N-terminal CB4_RS18095 65de56861c2bc29e7e71dee0a5caaaab 275 SUPERFAMILY SSF46785 27 114 9.37E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18095 65de56861c2bc29e7e71dee0a5caaaab 275 Gene3D G3DSA:1.10.10.10 1 84 2.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07015 e603388841f35d8e02c8e29039034c0f 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CB4_RS07015 e603388841f35d8e02c8e29039034c0f 66 Gene3D G3DSA:2.40.50.140 1 66 2.3E-28 T 29-03-2018 CB4_RS07015 e603388841f35d8e02c8e29039034c0f 66 PRINTS PR00050 Cold shock protein signature 39 57 2.6E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS07015 e603388841f35d8e02c8e29039034c0f 66 PRINTS PR00050 Cold shock protein signature 4 19 2.6E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS07015 e603388841f35d8e02c8e29039034c0f 66 PRINTS PR00050 Cold shock protein signature 24 33 2.6E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS07015 e603388841f35d8e02c8e29039034c0f 66 SMART SM00357 3 66 5.1E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CB4_RS07015 e603388841f35d8e02c8e29039034c0f 66 SUPERFAMILY SSF50249 1 65 1.44E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS07015 e603388841f35d8e02c8e29039034c0f 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.5E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS07015 e603388841f35d8e02c8e29039034c0f 66 PIRSF PIRSF002599 1 66 3.2E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CB4_RS06940 850a4f803a5367429f7ef1b4052cfd19 308 Pfam PF02690 Na+/Pi-cotransporter 14 148 4.3E-41 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CB4_RS06940 850a4f803a5367429f7ef1b4052cfd19 308 Pfam PF02690 Na+/Pi-cotransporter 169 252 3.4E-16 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CB4_RS06940 850a4f803a5367429f7ef1b4052cfd19 308 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 5 308 9.2E-78 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 CB4_RS17760 b208fcafba2dcb9504e4f2622645a35a 841 SUPERFAMILY SSF53955 61 267 1.38E-76 T 29-03-2018 IPR023346 Lysozyme-like domain CB4_RS17760 b208fcafba2dcb9504e4f2622645a35a 841 Pfam PF00912 Transglycosylase 71 245 2.2E-65 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CB4_RS17760 b208fcafba2dcb9504e4f2622645a35a 841 Gene3D G3DSA:1.10.3810.10 61 262 2.3E-80 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CB4_RS17760 b208fcafba2dcb9504e4f2622645a35a 841 SUPERFAMILY SSF56601 227 249 9.32E-111 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS17760 b208fcafba2dcb9504e4f2622645a35a 841 SUPERFAMILY SSF56601 279 641 9.32E-111 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS17760 b208fcafba2dcb9504e4f2622645a35a 841 Gene3D G3DSA:3.40.710.10 264 655 1.6E-107 T 29-03-2018 CB4_RS17760 b208fcafba2dcb9504e4f2622645a35a 841 Gene3D G3DSA:2.60.40.10 656 758 4.1E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS17760 b208fcafba2dcb9504e4f2622645a35a 841 Pfam PF00905 Penicillin binding protein transpeptidase domain 342 621 4.2E-48 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CB4_RS17760 b208fcafba2dcb9504e4f2622645a35a 841 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 81 625 2.9E-189 T 29-03-2018 CB4_RS18555 067bf0d80ee2c7f0b26d97e7aa4acf8c 166 Pfam PF00293 NUDIX domain 39 155 1.3E-18 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CB4_RS18555 067bf0d80ee2c7f0b26d97e7aa4acf8c 166 ProSitePatterns PS00893 Nudix box signature. 70 91 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CB4_RS18555 067bf0d80ee2c7f0b26d97e7aa4acf8c 166 SUPERFAMILY SSF55811 5 162 2.84E-35 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CB4_RS18555 067bf0d80ee2c7f0b26d97e7aa4acf8c 166 Gene3D G3DSA:2.20.70.10 3 33 8.9E-7 T 29-03-2018 CB4_RS18555 067bf0d80ee2c7f0b26d97e7aa4acf8c 166 Pfam PF14803 Nudix N-terminal 5 35 4.2E-6 T 29-03-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 CB4_RS18555 067bf0d80ee2c7f0b26d97e7aa4acf8c 166 Gene3D G3DSA:3.90.79.10 34 164 2.3E-28 T 29-03-2018 CB4_RS18675 ed84d1e88bac5bd147da53fc8e1d89c5 131 Gene3D G3DSA:3.90.79.10 1 130 6.3E-33 T 29-03-2018 CB4_RS18675 ed84d1e88bac5bd147da53fc8e1d89c5 131 Pfam PF00293 NUDIX domain 4 125 2.2E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CB4_RS18675 ed84d1e88bac5bd147da53fc8e1d89c5 131 SUPERFAMILY SSF55811 1 128 2.17E-34 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CB4_RS18675 ed84d1e88bac5bd147da53fc8e1d89c5 131 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CB4_RS18675 ed84d1e88bac5bd147da53fc8e1d89c5 131 PRINTS PR00502 NUDIX hydrolase family signature 47 62 6.0E-9 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CB4_RS18675 ed84d1e88bac5bd147da53fc8e1d89c5 131 PRINTS PR00502 NUDIX hydrolase family signature 33 47 6.0E-9 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CB4_RS05795 01af3d82958051c26f524f6b916d6044 376 Pfam PF05036 Sporulation related domain 173 237 2.9E-4 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CB4_RS05795 01af3d82958051c26f524f6b916d6044 376 Gene3D G3DSA:3.30.70.1070 174 244 3.1E-6 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CB4_RS05795 01af3d82958051c26f524f6b916d6044 376 SUPERFAMILY SSF110997 174 235 2.48E-6 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CB4_RS03530 c4b71ef3aa6b0460463e5c4503543935 313 Gene3D G3DSA:3.40.50.920 186 313 2.0E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS03530 c4b71ef3aa6b0460463e5c4503543935 313 SMART SM00861 9 174 7.3E-61 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CB4_RS03530 c4b71ef3aa6b0460463e5c4503543935 313 ProSitePatterns PS00802 Transketolase signature 2. 117 133 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CB4_RS03530 c4b71ef3aa6b0460463e5c4503543935 313 Pfam PF02780 Transketolase, C-terminal domain 185 305 1.6E-35 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CB4_RS03530 c4b71ef3aa6b0460463e5c4503543935 313 SUPERFAMILY SSF52922 182 313 6.41E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS03530 c4b71ef3aa6b0460463e5c4503543935 313 SUPERFAMILY SSF52518 4 176 7.85E-63 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS03530 c4b71ef3aa6b0460463e5c4503543935 313 Pfam PF02779 Transketolase, pyrimidine binding domain 7 172 3.6E-42 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CB4_RS03530 c4b71ef3aa6b0460463e5c4503543935 313 Gene3D G3DSA:3.40.50.970 1 185 8.4E-55 T 29-03-2018 CB4_RS17980 848ecd1ad3284b28eef3a375925e215c 110 Pfam PF06942 GlpM protein 15 91 2.1E-12 T 29-03-2018 IPR009707 Membrane protein GlpM/YdgC CB4_RS17980 848ecd1ad3284b28eef3a375925e215c 110 ProDom PD028709 MEMBRANE INNER YDGC GLPM ALGINATE BIOSYNTHESIS TRANSMEMBRANE REQUIRED FOR UNCHARACTERIZED 24 80 2.0E-6 T 29-03-2018 IPR009707 Membrane protein GlpM/YdgC CB4_RS12140 1ab9a7714bcda02e94716035051cec88 114 Gene3D G3DSA:3.40.250.10 3 110 6.9E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS12140 1ab9a7714bcda02e94716035051cec88 114 SUPERFAMILY SSF52821 5 108 2.1E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS12140 1ab9a7714bcda02e94716035051cec88 114 SMART SM00450 6 112 2.8E-9 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS12140 1ab9a7714bcda02e94716035051cec88 114 Pfam PF00581 Rhodanese-like domain 7 108 1.6E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 SMART SM01130 1 286 3.3E-131 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 Pfam PF00701 Dihydrodipicolinate synthetase family 2 283 2.4E-100 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 PIRSF PIRSF001365 1 287 3.6E-91 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 1.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 1.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 1.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 1.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 164 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 283 5.7E-110 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 Gene3D G3DSA:3.20.20.70 1 287 1.6E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 62.307 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CB4_RS09450 0b9754c546b58f46a1f398b7fadda43b 287 SUPERFAMILY SSF51569 2 285 4.81E-99 T 29-03-2018 CB4_RS16535 9b150ebf890d977f4f19d18f12c4bb0f 313 SUPERFAMILY SSF103481 49 148 3.4E-12 T 29-03-2018 CB4_RS16535 9b150ebf890d977f4f19d18f12c4bb0f 313 SUPERFAMILY SSF103481 203 290 7.32E-14 T 29-03-2018 CB4_RS16535 9b150ebf890d977f4f19d18f12c4bb0f 313 Pfam PF00892 EamA-like transporter family 15 144 2.1E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS16535 9b150ebf890d977f4f19d18f12c4bb0f 313 Pfam PF00892 EamA-like transporter family 155 290 2.4E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS10720 18ab20b234ded8c7ebc0784038d30ef7 223 Gene3D G3DSA:3.40.50.1580 7 223 4.3E-46 T 29-03-2018 CB4_RS10720 18ab20b234ded8c7ebc0784038d30ef7 223 Hamap MF_00991 Futalosine hydrolase [mqnB]. 26 220 24.914 T 29-03-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 CB4_RS10720 18ab20b234ded8c7ebc0784038d30ef7 223 Pfam PF01048 Phosphorylase superfamily 38 220 4.3E-25 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CB4_RS10720 18ab20b234ded8c7ebc0784038d30ef7 223 SUPERFAMILY SSF53167 13 203 1.96E-34 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CB4_RS10720 18ab20b234ded8c7ebc0784038d30ef7 223 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 13 218 8.7E-73 T 29-03-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 SUPERFAMILY SSF57716 11 46 1.37E-11 T 29-03-2018 CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 SMART SM00382 108 269 1.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 411 53.524 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 SMART SM00994 10 49 8.0E-24 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 2 407 1.6E-209 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 307 7.5E-50 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 313 391 7.5E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 SUPERFAMILY SSF52540 60 400 1.74E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 SMART SM01086 313 407 2.8E-34 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 Gene3D G3DSA:1.10.8.60 313 405 5.0E-35 T 29-03-2018 CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 Pfam PF06689 ClpX C4-type zinc finger 12 48 3.3E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CB4_RS05615 37bb1d03b9c9c9a9efaf37b0ca0482ca 424 Gene3D G3DSA:3.40.50.300 53 311 2.9E-69 T 29-03-2018 CB4_RS07600 bc724fa914669ce0cd05084b6ba480db 155 Gene3D G3DSA:1.20.1500.10 13 122 1.6E-27 T 29-03-2018 IPR023378 YheA/YmcA-like domain CB4_RS07600 bc724fa914669ce0cd05084b6ba480db 155 SUPERFAMILY SSF158622 10 130 7.33E-30 T 29-03-2018 IPR023378 YheA/YmcA-like domain CB4_RS07600 bc724fa914669ce0cd05084b6ba480db 155 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 14 120 9.9E-21 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CB4_RS20200 991d0704005c009781e5706b28c034f4 486 Pfam PF01425 Amidase 24 467 3.6E-165 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS20200 991d0704005c009781e5706b28c034f4 486 Gene3D G3DSA:3.90.1300.10 1 486 1.7E-177 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS20200 991d0704005c009781e5706b28c034f4 486 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 478 94.469 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS20200 991d0704005c009781e5706b28c034f4 486 ProSitePatterns PS00571 Amidases signature. 152 183 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CB4_RS20200 991d0704005c009781e5706b28c034f4 486 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 478 6.3E-201 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS20200 991d0704005c009781e5706b28c034f4 486 SUPERFAMILY SSF75304 4 484 4.32E-169 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS04720 e63d52391d1b71905cb13f5c29b40f4d 407 PIRSF PIRSF005572 20 404 1.2E-50 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CB4_RS04720 e63d52391d1b71905cb13f5c29b40f4d 407 Pfam PF00266 Aminotransferase class-V 23 391 1.3E-159 T 29-03-2018 IPR000192 Aminotransferase class V domain CB4_RS04720 e63d52391d1b71905cb13f5c29b40f4d 407 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CB4_RS04720 e63d52391d1b71905cb13f5c29b40f4d 407 SUPERFAMILY SSF53383 2 398 2.39E-129 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS04720 e63d52391d1b71905cb13f5c29b40f4d 407 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 4 403 1.2E-184 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CB4_RS04720 e63d52391d1b71905cb13f5c29b40f4d 407 Gene3D G3DSA:3.40.640.10 32 280 4.6E-61 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS04720 e63d52391d1b71905cb13f5c29b40f4d 407 Gene3D G3DSA:3.90.1150.10 281 398 3.5E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS09085 c01926ca4883d4f87bac25d24ca9ff95 100 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 64 80 2.4E-14 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CB4_RS09085 c01926ca4883d4f87bac25d24ca9ff95 100 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 85 98 2.4E-14 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CB4_RS09085 c01926ca4883d4f87bac25d24ca9ff95 100 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 30 46 2.4E-14 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CB4_RS09085 c01926ca4883d4f87bac25d24ca9ff95 100 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 14 100 1.2E-26 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CB4_RS09085 c01926ca4883d4f87bac25d24ca9ff95 100 Pfam PF02049 Flagellar hook-basal body complex protein FliE 17 100 6.6E-32 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CB4_RS09085 c01926ca4883d4f87bac25d24ca9ff95 100 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 2 100 18.777 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CB4_RS13085 0ac0008f3acd2eb2574ab597258f010d 159 Pfam PF07849 Protein of unknown function (DUF1641) 119 154 2.7E-15 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 CB4_RS06385 0583963c87b13128d2a33f6091945d7d 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 29-03-2018 IPR019844 Cold-shock conserved site CB4_RS06385 0583963c87b13128d2a33f6091945d7d 67 SUPERFAMILY SSF50249 2 66 3.19E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS06385 0583963c87b13128d2a33f6091945d7d 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 1.0E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS06385 0583963c87b13128d2a33f6091945d7d 67 PRINTS PR00050 Cold shock protein signature 5 20 4.7E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS06385 0583963c87b13128d2a33f6091945d7d 67 PRINTS PR00050 Cold shock protein signature 25 34 4.7E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS06385 0583963c87b13128d2a33f6091945d7d 67 PRINTS PR00050 Cold shock protein signature 40 58 4.7E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS06385 0583963c87b13128d2a33f6091945d7d 67 PIRSF PIRSF002599 1 67 1.6E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CB4_RS06385 0583963c87b13128d2a33f6091945d7d 67 Gene3D G3DSA:2.40.50.140 2 67 5.6E-27 T 29-03-2018 CB4_RS06385 0583963c87b13128d2a33f6091945d7d 67 SMART SM00357 4 67 8.8E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CB4_RS06645 5ae1a18d860c24c32caf5e181b4ae5ef 120 Pfam PF12438 Protein of unknown function (DUF3679) 21 75 5.3E-11 T 29-03-2018 IPR020534 Uncharacterised protein family YqxA CB4_RS17590 4bc741ddc43913e9e00db319a6223860 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 277 1.5E-36 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS17590 4bc741ddc43913e9e00db319a6223860 293 Gene3D G3DSA:1.10.3470.10 3 281 8.4E-46 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS03235 3f83846cc23fb01e3d165931ce2a7dad 308 Pfam PF00535 Glycosyl transferase family 2 10 166 2.2E-19 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CB4_RS03235 3f83846cc23fb01e3d165931ce2a7dad 308 Gene3D G3DSA:3.90.550.10 2 296 7.5E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS03235 3f83846cc23fb01e3d165931ce2a7dad 308 SUPERFAMILY SSF53448 8 219 1.22E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 7.5E-25 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 6.3E-31 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 SUPERFAMILY SSF46906 67 140 2.22E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.0E-64 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.268 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 Gene3D G3DSA:3.30.1550.10 3 71 4.8E-36 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 SMART SM00649 9 140 2.6E-85 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 1.0E-15 T 29-03-2018 CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 SUPERFAMILY SSF54747 3 72 1.96E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CB4_RS01160 693c2326c570885f398ae82886c66f9e 141 Gene3D G3DSA:1.10.10.250 72 140 9.0E-24 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CB4_RS04420 20280234ac0bf6cf6f09e115445d8762 384 Pfam PF03845 Spore germination protein 6 316 2.1E-45 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS04420 20280234ac0bf6cf6f09e115445d8762 384 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 7 357 1.3E-46 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS13965 b5ddf0ee62e546ef57464132cc4db922 519 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 501 1.8E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS13965 b5ddf0ee62e546ef57464132cc4db922 519 Gene3D G3DSA:3.30.300.30 411 517 3.3E-28 T 29-03-2018 CB4_RS13965 b5ddf0ee62e546ef57464132cc4db922 519 SUPERFAMILY SSF56801 8 513 3.14E-152 T 29-03-2018 CB4_RS13965 b5ddf0ee62e546ef57464132cc4db922 519 Gene3D G3DSA:2.30.38.10 329 410 2.3E-21 T 29-03-2018 CB4_RS13965 b5ddf0ee62e546ef57464132cc4db922 519 Gene3D G3DSA:3.40.50.980 176 328 2.4E-42 T 29-03-2018 CB4_RS13965 b5ddf0ee62e546ef57464132cc4db922 519 Pfam PF00501 AMP-binding enzyme 15 417 5.2E-96 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS13965 b5ddf0ee62e546ef57464132cc4db922 519 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS13965 b5ddf0ee62e546ef57464132cc4db922 519 Gene3D G3DSA:3.40.50.980 6 175 8.3E-42 T 29-03-2018 CB4_RS05200 30075f02c7800c5fcb7beca1441dae71 117 SUPERFAMILY SSF89360 1 96 3.53E-31 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CB4_RS05200 30075f02c7800c5fcb7beca1441dae71 117 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CB4_RS05200 30075f02c7800c5fcb7beca1441dae71 117 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 106 2.6E-39 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CB4_RS05200 30075f02c7800c5fcb7beca1441dae71 117 Gene3D G3DSA:2.60.300.12 1 110 3.3E-41 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CB4_RS05200 30075f02c7800c5fcb7beca1441dae71 117 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 102 1.7E-22 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 Pfam PF12838 4Fe-4S dicluster domain 8 52 1.9E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 311 394 2.6E-32 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 Gene3D G3DSA:3.30.70.20 41 89 7.0E-5 T 29-03-2018 CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 SUPERFAMILY SSF52467 311 430 5.95E-44 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 Pfam PF01012 Electron transfer flavoprotein domain 111 285 3.6E-38 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 Gene3D G3DSA:3.40.50.1220 307 437 1.9E-52 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 Gene3D G3DSA:3.30.70.20 2 40 2.2E-12 T 29-03-2018 CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 SMART SM00893 111 300 3.5E-35 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 SUPERFAMILY SSF54862 3 58 3.86E-18 T 29-03-2018 CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 SUPERFAMILY SSF52402 110 304 3.28E-49 T 29-03-2018 CB4_RS17155 ac2bae7c3ad16d04eb85ac4ee068bfa4 443 Gene3D G3DSA:3.40.50.620 97 304 8.8E-49 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS18465 3481f81f75cfa0476beee35ab918d3e6 407 Pfam PF04235 Protein of unknown function (DUF418) 229 388 3.0E-42 T 29-03-2018 IPR007349 Domain of unknown function DUF418 CB4_RS15840 53fac1066044190f3533d947756c3848 125 Gene3D G3DSA:2.30.29.50 13 102 6.8E-39 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain CB4_RS15840 53fac1066044190f3533d947756c3848 125 Pfam PF08000 Bacterial PH domain 3 123 8.6E-53 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain CB4_RS15840 53fac1066044190f3533d947756c3848 125 SUPERFAMILY SSF50729 6 124 8.2E-47 T 29-03-2018 IPR011993 PH domain-like CB4_RS09680 8eee141171a042370fc5d41f53768856 216 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CB4_RS09680 8eee141171a042370fc5d41f53768856 216 SUPERFAMILY SSF51161 30 202 5.13E-45 T 29-03-2018 IPR011004 Trimeric LpxA-like CB4_RS09680 8eee141171a042370fc5d41f53768856 216 Gene3D G3DSA:2.160.10.10 3 211 2.7E-43 T 29-03-2018 CB4_RS09680 8eee141171a042370fc5d41f53768856 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 1.2E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CB4_RS12830 c876e5fd276dbe30a1d1fafc933099cd 300 Pfam PF00892 EamA-like transporter family 8 139 1.3E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS12830 c876e5fd276dbe30a1d1fafc933099cd 300 Pfam PF00892 EamA-like transporter family 152 286 1.2E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS12830 c876e5fd276dbe30a1d1fafc933099cd 300 SUPERFAMILY SSF103481 38 141 1.57E-18 T 29-03-2018 CB4_RS12830 c876e5fd276dbe30a1d1fafc933099cd 300 SUPERFAMILY SSF103481 190 290 1.96E-12 T 29-03-2018 CB4_RS06195 fb1cfe6497e1e50e19a5c690f7390341 172 SUPERFAMILY SSF88874 1 166 1.28E-45 T 29-03-2018 CB4_RS06195 fb1cfe6497e1e50e19a5c690f7390341 172 Gene3D G3DSA:3.90.1340.10 1 53 2.5E-21 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS06195 fb1cfe6497e1e50e19a5c690f7390341 172 Pfam PF07484 Phage Tail Collar Domain 6 62 1.1E-26 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS06195 fb1cfe6497e1e50e19a5c690f7390341 172 Gene3D G3DSA:4.10.1070.10 54 156 2.0E-4 T 29-03-2018 CB4_RS01830 54350db882c12acf4cbfa5fb55257034 511 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 327 463 2.2E-45 T 29-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain CB4_RS01830 54350db882c12acf4cbfa5fb55257034 511 SUPERFAMILY SSF100950 226 495 7.12E-83 T 29-03-2018 CB4_RS01830 54350db882c12acf4cbfa5fb55257034 511 SUPERFAMILY SSF100950 4 222 3.02E-56 T 29-03-2018 CB4_RS01830 54350db882c12acf4cbfa5fb55257034 511 Gene3D G3DSA:3.40.1080.10 13 233 1.4E-25 T 29-03-2018 CB4_RS01830 54350db882c12acf4cbfa5fb55257034 511 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 13 494 1.1E-220 T 29-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 CB4_RS01830 54350db882c12acf4cbfa5fb55257034 511 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 12 206 1.9E-21 T 29-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 CB4_RS01830 54350db882c12acf4cbfa5fb55257034 511 Gene3D G3DSA:3.40.1080.10 234 498 7.8E-61 T 29-03-2018 CB4_RS00945 f6b2ce0a17fa2f0dfac8444782d3759b 96 Pfam PF00276 Ribosomal protein L23 6 88 2.8E-34 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CB4_RS00945 f6b2ce0a17fa2f0dfac8444782d3759b 96 SUPERFAMILY SSF54189 2 94 7.55E-35 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS00945 f6b2ce0a17fa2f0dfac8444782d3759b 96 Gene3D G3DSA:3.30.70.330 2 96 4.3E-34 T 29-03-2018 CB4_RS00945 f6b2ce0a17fa2f0dfac8444782d3759b 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 23.938 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CB4_RS17305 648d57dc565ef7a9e41691cc26d2e9d5 210 PIRSF PIRSF021278 2 210 7.8E-81 T 29-03-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 CB4_RS17305 648d57dc565ef7a9e41691cc26d2e9d5 210 Gene3D G3DSA:3.40.630.30 1 210 6.3E-49 T 29-03-2018 CB4_RS17305 648d57dc565ef7a9e41691cc26d2e9d5 210 SUPERFAMILY SSF55729 46 121 3.78E-7 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS15045 69990c776156be0923964313f98c6d4a 67 SMART SM00914 21 57 3.4E-11 T 29-03-2018 IPR014957 IDEAL domain CB4_RS15045 69990c776156be0923964313f98c6d4a 67 Pfam PF08858 IDEAL domain 21 57 1.4E-14 T 29-03-2018 IPR014957 IDEAL domain CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 207 1.4E-27 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 58 71 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 Pfam PF08281 Sigma-70, region 4 160 203 1.9E-8 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 SUPERFAMILY SSF88946 16 103 1.13E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 Pfam PF04542 Sigma-70 region 2 34 103 4.3E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 SUPERFAMILY SSF88659 121 208 4.45E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 PIRSF PIRSF002939 2 214 4.1E-110 T 29-03-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 Gene3D G3DSA:1.10.1740.10 11 114 2.8E-19 T 29-03-2018 CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 Gene3D G3DSA:1.10.10.10 136 214 6.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS01185 683e984af497fcc20a1f9ae803fa5cd2 215 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 11 208 1.4E-112 T 29-03-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS03930 b056c1f178475d2462128e71b88c0d9c 294 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 24 225 3.0E-69 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS03930 b056c1f178475d2462128e71b88c0d9c 294 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 2.3E-21 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CB4_RS03930 b056c1f178475d2462128e71b88c0d9c 294 PIRSF PIRSF006483 4 293 4.5E-99 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS18155 685227f46d910b8771cf23867dbdba70 312 Gene3D G3DSA:3.40.50.2300 156 309 1.2E-47 T 29-03-2018 CB4_RS18155 685227f46d910b8771cf23867dbdba70 312 Pfam PF13407 Periplasmic binding protein domain 44 297 2.5E-71 T 29-03-2018 IPR025997 Periplasmic binding protein CB4_RS18155 685227f46d910b8771cf23867dbdba70 312 Gene3D G3DSA:3.40.50.2300 37 155 6.7E-33 T 29-03-2018 CB4_RS18155 685227f46d910b8771cf23867dbdba70 312 SUPERFAMILY SSF53822 37 311 5.13E-94 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS06275 d6fba821e1331eefbf44b436449c241d 452 Gene3D G3DSA:2.30.38.10 281 354 3.1E-7 T 29-03-2018 CB4_RS06275 d6fba821e1331eefbf44b436449c241d 452 Gene3D G3DSA:3.40.50.980 33 194 3.9E-19 T 29-03-2018 CB4_RS06275 d6fba821e1331eefbf44b436449c241d 452 Gene3D G3DSA:3.40.50.980 195 280 1.7E-16 T 29-03-2018 CB4_RS06275 d6fba821e1331eefbf44b436449c241d 452 Gene3D G3DSA:3.30.300.30 355 452 3.5E-26 T 29-03-2018 CB4_RS06275 d6fba821e1331eefbf44b436449c241d 452 Pfam PF00501 AMP-binding enzyme 207 361 1.6E-24 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS06275 d6fba821e1331eefbf44b436449c241d 452 Pfam PF00501 AMP-binding enzyme 43 205 2.6E-14 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS06275 d6fba821e1331eefbf44b436449c241d 452 SUPERFAMILY SSF56801 34 452 1.28E-83 T 29-03-2018 CB4_RS06275 d6fba821e1331eefbf44b436449c241d 452 Pfam PF13193 AMP-binding enzyme C-terminal domain 370 445 5.2E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS10585 e3a4e55a703435bd5d10ca2fed9c4c5e 706 SUPERFAMILY SSF51905 207 528 2.45E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS10585 e3a4e55a703435bd5d10ca2fed9c4c5e 706 SUPERFAMILY SSF51905 656 696 2.45E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS10585 e3a4e55a703435bd5d10ca2fed9c4c5e 706 Pfam PF01593 Flavin containing amine oxidoreductase 217 693 6.0E-24 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CB4_RS10585 e3a4e55a703435bd5d10ca2fed9c4c5e 706 Gene3D G3DSA:3.50.50.60 195 700 1.3E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS17985 d54f17ccfb23ccc22e9f998369bfe1ad 160 Pfam PF13420 Acetyltransferase (GNAT) domain 3 143 6.2E-18 T 29-03-2018 CB4_RS17985 d54f17ccfb23ccc22e9f998369bfe1ad 160 Gene3D G3DSA:3.40.630.30 1 157 1.8E-29 T 29-03-2018 CB4_RS17985 d54f17ccfb23ccc22e9f998369bfe1ad 160 SUPERFAMILY SSF55729 2 152 1.05E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS09505 99fe8ee80462d98152dcf60234adf354 435 Gene3D G3DSA:3.90.350.10 95 322 2.2E-19 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CB4_RS09505 99fe8ee80462d98152dcf60234adf354 435 Pfam PF01609 Transposase DDE domain 108 333 1.1E-15 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CB4_RS09505 99fe8ee80462d98152dcf60234adf354 435 SUPERFAMILY SSF53098 102 340 1.37E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS04615 21e0725e58be4c63805048f20150801a 195 Gene3D G3DSA:4.10.1070.10 55 176 7.0E-8 T 29-03-2018 CB4_RS04615 21e0725e58be4c63805048f20150801a 195 SUPERFAMILY SSF88874 2 189 1.83E-45 T 29-03-2018 CB4_RS04615 21e0725e58be4c63805048f20150801a 195 Pfam PF07484 Phage Tail Collar Domain 6 62 5.7E-26 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS04615 21e0725e58be4c63805048f20150801a 195 Gene3D G3DSA:3.90.1340.10 1 54 3.8E-23 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 Gene3D G3DSA:3.30.2090.10 182 270 2.8E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 SUPERFAMILY SSF82866 296 493 1.1E-42 T 29-03-2018 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 SUPERFAMILY SSF82714 184 270 8.76E-7 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 SUPERFAMILY SSF82693 138 182 6.8E-14 T 29-03-2018 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 SUPERFAMILY SSF82693 272 327 6.8E-14 T 29-03-2018 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 Gene3D G3DSA:1.20.1640.10 780 998 4.0E-40 T 29-03-2018 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 Gene3D G3DSA:1.20.1640.10 271 497 2.4E-44 T 29-03-2018 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 Pfam PF00873 AcrB/AcrD/AcrF family 5 994 3.6E-232 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 Gene3D G3DSA:3.30.70.1430 554 687 1.4E-11 T 29-03-2018 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 Gene3D G3DSA:3.30.70.1430 41 140 1.6E-22 T 29-03-2018 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 9.2E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 9.2E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 9.2E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 9.2E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 9.2E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 9.2E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 9.2E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 9.2E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 Gene3D G3DSA:3.30.2090.10 691 779 4.3E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 SUPERFAMILY SSF82693 555 616 7.85E-8 T 29-03-2018 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 SUPERFAMILY SSF82714 693 775 7.19E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 SUPERFAMILY SSF82693 41 132 5.23E-19 T 29-03-2018 CB4_RS20700 960dfde807bccb4fc9ad24535374bb46 1023 SUPERFAMILY SSF82866 778 1000 5.36E-46 T 29-03-2018 CB4_RS19135 d23ed1089ca0ca893b9ce74aec7a7521 102 Pfam PF04693 Archaeal putative transposase ISC1217 8 48 3.5E-6 T 29-03-2018 IPR006783 Transposase, ISC1217 CB4_RS19135 d23ed1089ca0ca893b9ce74aec7a7521 102 Gene3D G3DSA:3.90.350.10 1 53 1.0E-10 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CB4_RS19135 d23ed1089ca0ca893b9ce74aec7a7521 102 SUPERFAMILY SSF53098 8 96 4.48E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS16870 7f8293f968c1898a96fe0d9ecbce68e3 166 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 7 154 1.3E-25 T 29-03-2018 IPR018639 Domain of unknown function DUF2062 CB4_RS04990 4644c635fa6666790fee3bfef9e08881 140 Pfam PF01934 Protein of unknown function DUF86 32 131 9.0E-17 T 29-03-2018 IPR008201 Protein of unknown function DUF86 CB4_RS04990 4644c635fa6666790fee3bfef9e08881 140 Gene3D G3DSA:1.20.120.580 1 140 6.3E-28 T 29-03-2018 IPR008201 Protein of unknown function DUF86 CB4_RS08415 721dc1993dd0f9c8b8580626cd16f117 212 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 212 30.464 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS08415 721dc1993dd0f9c8b8580626cd16f117 212 Gene3D G3DSA:3.40.50.2020 5 212 6.8E-41 T 29-03-2018 CB4_RS08415 721dc1993dd0f9c8b8580626cd16f117 212 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 15 176 1.2E-44 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CB4_RS08415 721dc1993dd0f9c8b8580626cd16f117 212 Pfam PF00156 Phosphoribosyl transferase domain 50 155 1.7E-16 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CB4_RS08415 721dc1993dd0f9c8b8580626cd16f117 212 SUPERFAMILY SSF53271 13 211 2.62E-55 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CB4_RS14760 38f48e7c7d97ed7de415f6eeed647124 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 2.2E-32 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CB4_RS14760 38f48e7c7d97ed7de415f6eeed647124 288 Gene3D G3DSA:3.40.50.970 72 288 8.4E-47 T 29-03-2018 CB4_RS14760 38f48e7c7d97ed7de415f6eeed647124 288 Gene3D G3DSA:3.40.50.970 5 71 7.5E-15 T 29-03-2018 CB4_RS14760 38f48e7c7d97ed7de415f6eeed647124 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 259 6.0E-91 T 29-03-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate CB4_RS14760 38f48e7c7d97ed7de415f6eeed647124 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 263 2.3E-20 T 29-03-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal CB4_RS14760 38f48e7c7d97ed7de415f6eeed647124 288 SUPERFAMILY SSF52518 12 285 1.11E-77 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS01495 308af48bbd5c1afc826d59422afcf080 97 Gene3D G3DSA:3.30.1120.40 1 83 4.1E-37 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CB4_RS01495 308af48bbd5c1afc826d59422afcf080 97 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 28.136 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CB4_RS01495 308af48bbd5c1afc826d59422afcf080 97 SUPERFAMILY SSF160537 1 83 6.41E-33 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CB4_RS01495 308af48bbd5c1afc826d59422afcf080 97 Pfam PF04026 SpoVG 1 81 1.0E-36 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CB4_RS03185 e03364be4db7e05405ef580acd514b01 232 Pfam PF08889 WbqC-like protein family 8 224 1.3E-73 T 29-03-2018 IPR014985 WbqC-like protein family CB4_RS19200 4deeb9a28d275f6cfb4ef9ca52ee9ea1 397 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 118 394 3.5E-44 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CB4_RS19200 4deeb9a28d275f6cfb4ef9ca52ee9ea1 397 Gene3D G3DSA:3.30.70.150 1 112 9.4E-26 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CB4_RS19200 4deeb9a28d275f6cfb4ef9ca52ee9ea1 397 SUPERFAMILY SSF54966 2 112 1.44E-25 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CB4_RS19200 4deeb9a28d275f6cfb4ef9ca52ee9ea1 397 SUPERFAMILY SSF51649 113 395 1.57E-83 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CB4_RS19200 4deeb9a28d275f6cfb4ef9ca52ee9ea1 397 Gene3D G3DSA:3.20.20.110 113 397 1.9E-89 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CB4_RS06335 89fb2720a5b5f3da487689ef0f4a3b78 69 SUPERFAMILY SSF88946 7 67 4.4E-9 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS06335 89fb2720a5b5f3da487689ef0f4a3b78 69 Gene3D G3DSA:1.10.601.10 9 69 6.9E-7 T 29-03-2018 CB4_RS11625 41654f03cec83ea8040ab95faa5ed988 171 Gene3D G3DSA:3.40.960.10 52 169 7.4E-24 T 29-03-2018 CB4_RS11625 41654f03cec83ea8040ab95faa5ed988 171 Pfam PF04480 Protein of unknown function (DUF559) 70 145 2.2E-12 T 29-03-2018 IPR007569 Domain of unknown function DUF559 CB4_RS11625 41654f03cec83ea8040ab95faa5ed988 171 SUPERFAMILY SSF52980 42 145 1.13E-14 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CB4_RS07180 36bdac2209ae4db6693ca863d0886f28 242 SUPERFAMILY SSF53335 7 136 1.78E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS07180 36bdac2209ae4db6693ca863d0886f28 242 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 21 230 7.1E-63 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CB4_RS07180 36bdac2209ae4db6693ca863d0886f28 242 Gene3D G3DSA:3.40.50.150 2 161 3.2E-16 T 29-03-2018 CB4_RS07180 36bdac2209ae4db6693ca863d0886f28 242 PIRSF PIRSF018637 2 237 6.3E-76 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CB4_RS03625 1ed0226bbf6016ce8cf53c559ed699ae 235 Gene3D G3DSA:1.10.720.40 118 141 6.2E-6 T 29-03-2018 IPR011015 LEM/LEM-like domain CB4_RS03625 1ed0226bbf6016ce8cf53c559ed699ae 235 Gene3D G3DSA:1.10.720.40 73 95 1.5E-4 T 29-03-2018 IPR011015 LEM/LEM-like domain CB4_RS03625 1ed0226bbf6016ce8cf53c559ed699ae 235 Gene3D G3DSA:1.10.720.40 165 201 5.3E-5 T 29-03-2018 IPR011015 LEM/LEM-like domain CB4_RS03625 1ed0226bbf6016ce8cf53c559ed699ae 235 SUPERFAMILY SSF47473 104 223 9.46E-6 T 29-03-2018 IPR011992 EF-hand domain pair CB4_RS03625 1ed0226bbf6016ce8cf53c559ed699ae 235 Gene3D G3DSA:3.30.2210.10 16 72 2.2E-5 T 29-03-2018 CB4_RS03625 1ed0226bbf6016ce8cf53c559ed699ae 235 Gene3D G3DSA:3.30.2210.10 96 117 9.8E-5 T 29-03-2018 CB4_RS03625 1ed0226bbf6016ce8cf53c559ed699ae 235 Gene3D G3DSA:3.30.2210.10 142 164 1.9E-5 T 29-03-2018 CB4_RS03625 1ed0226bbf6016ce8cf53c559ed699ae 235 Gene3D G3DSA:1.10.720.40 202 231 1.9E-4 T 29-03-2018 IPR011015 LEM/LEM-like domain CB4_RS00885 95a3d4c6483da25dba43ddb1a9c22bc3 132 SUPERFAMILY SSF56047 2 132 1.13E-49 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00885 95a3d4c6483da25dba43ddb1a9c22bc3 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00885 95a3d4c6483da25dba43ddb1a9c22bc3 132 Gene3D G3DSA:3.30.1490.10 70 130 1.9E-22 T 29-03-2018 CB4_RS00885 95a3d4c6483da25dba43ddb1a9c22bc3 132 Gene3D G3DSA:3.30.1370.30 1 67 9.8E-28 T 29-03-2018 CB4_RS00885 95a3d4c6483da25dba43ddb1a9c22bc3 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.392 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS00885 95a3d4c6483da25dba43ddb1a9c22bc3 132 Pfam PF00410 Ribosomal protein S8 5 132 1.4E-54 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CB4_RS13950 520f935cf5d065d72d65b014457f25b0 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 1.5E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS13950 520f935cf5d065d72d65b014457f25b0 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 1.5E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS13950 520f935cf5d065d72d65b014457f25b0 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 1.5E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS13950 520f935cf5d065d72d65b014457f25b0 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 1.5E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS13950 520f935cf5d065d72d65b014457f25b0 259 Gene3D G3DSA:3.40.50.1820 2 256 8.2E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS13950 520f935cf5d065d72d65b014457f25b0 259 Pfam PF00561 alpha/beta hydrolase fold 21 121 8.0E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS13950 520f935cf5d065d72d65b014457f25b0 259 SUPERFAMILY SSF53474 2 252 2.13E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS13095 b36b44cea566d1eaf53336cf61ffc6fa 269 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 267 15.466 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CB4_RS13095 b36b44cea566d1eaf53336cf61ffc6fa 269 Pfam PF02673 Bacitracin resistance protein BacA 7 262 5.1E-71 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CB4_RS01580 50f56588b5e948bd7e452530a6dc981a 326 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 15 194 6.7E-61 T 29-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CB4_RS01580 50f56588b5e948bd7e452530a6dc981a 326 SUPERFAMILY SSF52540 3 193 1.13E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01580 50f56588b5e948bd7e452530a6dc981a 326 Gene3D G3DSA:3.40.50.300 9 164 6.9E-31 T 29-03-2018 CB4_RS01580 50f56588b5e948bd7e452530a6dc981a 326 Gene3D G3DSA:1.20.272.10 205 326 4.9E-21 T 29-03-2018 CB4_RS01580 50f56588b5e948bd7e452530a6dc981a 326 Pfam PF13177 DNA polymerase III, delta subunit 9 165 1.5E-56 T 29-03-2018 CB4_RS07930 67cd1a9bfe71e59f14b96d42ad9396d0 172 Pfam PF00364 Biotin-requiring enzyme 96 167 9.3E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CB4_RS07930 67cd1a9bfe71e59f14b96d42ad9396d0 172 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 3 170 2.3E-50 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CB4_RS07930 67cd1a9bfe71e59f14b96d42ad9396d0 172 SUPERFAMILY SSF51230 94 169 4.97E-21 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS07930 67cd1a9bfe71e59f14b96d42ad9396d0 172 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 99 112 4.9E-14 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CB4_RS07930 67cd1a9bfe71e59f14b96d42ad9396d0 172 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 131 144 4.9E-14 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CB4_RS07930 67cd1a9bfe71e59f14b96d42ad9396d0 172 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 116 130 4.9E-14 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CB4_RS07930 67cd1a9bfe71e59f14b96d42ad9396d0 172 Gene3D G3DSA:2.40.50.100 6 171 8.5E-15 T 29-03-2018 CB4_RS20075 5c63e4c9b5b4f956afcc0cfb36ff1d7b 401 Pfam PF01385 Probable transposase 170 282 8.0E-11 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS20075 5c63e4c9b5b4f956afcc0cfb36ff1d7b 401 Pfam PF07282 Putative transposase DNA-binding domain 313 377 8.8E-20 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS20075 5c63e4c9b5b4f956afcc0cfb36ff1d7b 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 251 340 3.8E-12 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CB4_RS14910 8d06e7dce443c2d64cff3bb1d5a895a3 243 SUPERFAMILY SSF158499 130 195 7.98E-19 T 29-03-2018 IPR006343 DnaD domain CB4_RS14910 8d06e7dce443c2d64cff3bb1d5a895a3 243 Pfam PF07261 Replication initiation and membrane attachment 131 202 5.3E-25 T 29-03-2018 IPR006343 DnaD domain CB4_RS14910 8d06e7dce443c2d64cff3bb1d5a895a3 243 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 129 200 7.6E-22 T 29-03-2018 IPR006343 DnaD domain CB4_RS14910 8d06e7dce443c2d64cff3bb1d5a895a3 243 Gene3D G3DSA:1.10.10.630 142 200 8.9E-23 T 29-03-2018 IPR034829 DnaD-like domain CB4_RS14910 8d06e7dce443c2d64cff3bb1d5a895a3 243 Gene3D G3DSA:1.10.10.10 2 141 5.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13285 0da4cb617bd5dbc80794a3aa9462afff 224 SUPERFAMILY SSF46894 123 222 5.57E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS13285 0da4cb617bd5dbc80794a3aa9462afff 224 SUPERFAMILY SSF52172 2 129 1.99E-35 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS13285 0da4cb617bd5dbc80794a3aa9462afff 224 Gene3D G3DSA:1.10.10.10 124 224 3.5E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13285 0da4cb617bd5dbc80794a3aa9462afff 224 Gene3D G3DSA:3.40.50.2300 1 123 1.1E-30 T 29-03-2018 CB4_RS13285 0da4cb617bd5dbc80794a3aa9462afff 224 Pfam PF00072 Response regulator receiver domain 3 114 2.7E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13285 0da4cb617bd5dbc80794a3aa9462afff 224 SMART SM00448 1 113 8.4E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS13285 0da4cb617bd5dbc80794a3aa9462afff 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 222 2.7E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS13285 0da4cb617bd5dbc80794a3aa9462afff 224 SMART SM00862 146 222 4.4E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS19875 7d5254bf1e40bccd750a66782e7346b2 191 Pfam PF00877 NlpC/P60 family 82 189 1.2E-23 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CB4_RS19875 7d5254bf1e40bccd750a66782e7346b2 191 Gene3D G3DSA:3.90.1720.10 63 191 8.9E-39 T 29-03-2018 CB4_RS19875 7d5254bf1e40bccd750a66782e7346b2 191 SUPERFAMILY SSF54001 68 190 4.9E-40 T 29-03-2018 CB4_RS18000 b660aa976bb6e3c108f27bd53abf5eb5 292 Gene3D G3DSA:3.20.20.370 37 281 3.5E-46 T 29-03-2018 CB4_RS18000 b660aa976bb6e3c108f27bd53abf5eb5 292 SUPERFAMILY SSF88713 96 280 1.21E-49 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS18000 b660aa976bb6e3c108f27bd53abf5eb5 292 Pfam PF01522 Polysaccharide deacetylase 96 214 7.8E-27 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS14550 7f823103e848199dd9b6d83e2b38e7ae 170 Gene3D G3DSA:1.20.120.450 1 170 3.4E-22 T 29-03-2018 CB4_RS14550 7f823103e848199dd9b6d83e2b38e7ae 170 SUPERFAMILY SSF109854 7 163 4.76E-27 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CB4_RS14550 7f823103e848199dd9b6d83e2b38e7ae 170 Pfam PF05163 DinB family 4 166 5.5E-36 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CB4_RS18850 a746b3384c7076fb353b2aba81979bb2 133 SMART SM01321 11 130 2.6E-43 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CB4_RS18850 a746b3384c7076fb353b2aba81979bb2 133 SUPERFAMILY SSF143422 1 131 8.24E-47 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CB4_RS18850 a746b3384c7076fb353b2aba81979bb2 133 Pfam PF01797 Transposase IS200 like 11 130 6.6E-42 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CB4_RS18850 a746b3384c7076fb353b2aba81979bb2 133 Gene3D G3DSA:3.30.70.1290 2 133 3.6E-26 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 SMART SM00283 380 655 1.6E-85 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 SMART SM00304 299 351 4.5E-19 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 Pfam PF02743 Cache domain 37 261 4.3E-26 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 Pfam PF00672 HAMP domain 299 347 9.9E-18 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 Gene3D G3DSA:1.10.287.950 414 657 8.2E-55 T 29-03-2018 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 Gene3D G3DSA:1.10.287.950 326 413 2.5E-7 T 29-03-2018 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 426 609 8.4E-45 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 SUPERFAMILY SSF58104 386 654 2.09E-73 T 29-03-2018 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 SUPERFAMILY SSF58104 319 353 2.09E-73 T 29-03-2018 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 Gene3D G3DSA:3.30.450.20 32 165 4.8E-20 T 29-03-2018 CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 SUPERFAMILY SSF103190 97 189 5.1E-10 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS02745 506a83f64cc6cf321e8f3bd1e937a810 657 Gene3D G3DSA:3.30.450.20 166 268 8.7E-16 T 29-03-2018 CB4_RS20750 a7f7e539bca24cda8a4874f2b3aa8b9c 419 Gene3D G3DSA:3.40.630.10 1 302 4.4E-60 T 29-03-2018 CB4_RS20750 a7f7e539bca24cda8a4874f2b3aa8b9c 419 Pfam PF07687 Peptidase dimerisation domain 200 306 7.2E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CB4_RS20750 a7f7e539bca24cda8a4874f2b3aa8b9c 419 Gene3D G3DSA:3.40.630.10 303 414 1.4E-5 T 29-03-2018 CB4_RS20750 a7f7e539bca24cda8a4874f2b3aa8b9c 419 Pfam PF01546 Peptidase family M20/M25/M40 95 409 3.0E-36 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CB4_RS20750 a7f7e539bca24cda8a4874f2b3aa8b9c 419 SUPERFAMILY SSF53187 4 194 5.71E-59 T 29-03-2018 CB4_RS20750 a7f7e539bca24cda8a4874f2b3aa8b9c 419 SUPERFAMILY SSF53187 330 415 5.71E-59 T 29-03-2018 CB4_RS20750 a7f7e539bca24cda8a4874f2b3aa8b9c 419 SUPERFAMILY SSF55031 201 305 1.94E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CB4_RS20750 a7f7e539bca24cda8a4874f2b3aa8b9c 419 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 18 404 3.9E-103 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CB4_RS14700 eb8475d04413686c7cd6cc50885aad9b 513 SMART SM00857 4 156 9.2E-40 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS14700 eb8475d04413686c7cd6cc50885aad9b 513 SUPERFAMILY SSF53041 4 156 3.27E-28 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS14700 eb8475d04413686c7cd6cc50885aad9b 513 Pfam PF13408 Recombinase zinc beta ribbon domain 308 369 2.1E-13 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain CB4_RS14700 eb8475d04413686c7cd6cc50885aad9b 513 Pfam PF00239 Resolvase, N terminal domain 4 156 2.2E-30 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CB4_RS14700 eb8475d04413686c7cd6cc50885aad9b 513 Gene3D G3DSA:3.40.50.1390 2 162 1.1E-37 T 29-03-2018 CB4_RS14700 eb8475d04413686c7cd6cc50885aad9b 513 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CB4_RS14700 eb8475d04413686c7cd6cc50885aad9b 513 Pfam PF07508 Recombinase 179 293 1.8E-21 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CB4_RS10775 06e4c12f0d908eb21186929c5d22cab3 81 SUPERFAMILY SSF89447 1 53 4.06E-15 T 29-03-2018 CB4_RS10775 06e4c12f0d908eb21186929c5d22cab3 81 Gene3D G3DSA:2.10.260.10 1 48 4.9E-19 T 29-03-2018 CB4_RS10775 06e4c12f0d908eb21186929c5d22cab3 81 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 1.5E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS10775 06e4c12f0d908eb21186929c5d22cab3 81 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 49 1.3E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS10775 06e4c12f0d908eb21186929c5d22cab3 81 SMART SM00966 8 51 1.1E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS05545 8433264c48586d46e38b451edcc2f7c8 249 Gene3D G3DSA:1.10.1060.10 112 248 3.5E-16 T 29-03-2018 CB4_RS05545 8433264c48586d46e38b451edcc2f7c8 249 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 10 232 1.4E-37 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS05545 8433264c48586d46e38b451edcc2f7c8 249 SUPERFAMILY SSF54292 3 111 1.15E-21 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CB4_RS05545 8433264c48586d46e38b451edcc2f7c8 249 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 154 165 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS05545 8433264c48586d46e38b451edcc2f7c8 249 Pfam PF13183 4Fe-4S dicluster domain 150 225 2.8E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS05545 8433264c48586d46e38b451edcc2f7c8 249 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 116 1.0E-29 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS05545 8433264c48586d46e38b451edcc2f7c8 249 SUPERFAMILY SSF46548 113 238 4.01E-25 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CB4_RS05545 8433264c48586d46e38b451edcc2f7c8 249 Gene3D G3DSA:3.10.20.30 1 110 6.7E-25 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS12190 fe4843406f3ee0b9c28cc194604fafa5 218 Gene3D G3DSA:3.40.50.10320 2 218 3.0E-40 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CB4_RS12190 fe4843406f3ee0b9c28cc194604fafa5 218 SUPERFAMILY SSF102588 4 214 1.05E-39 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CB4_RS12190 fe4843406f3ee0b9c28cc194604fafa5 218 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 121 4.8E-20 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CB4_RS03815 5d26de9610dfdf1276351df2737d391c 86 PRINTS PR00107 Phosphocarrier protein signature 14 30 2.8E-19 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CB4_RS03815 5d26de9610dfdf1276351df2737d391c 86 PRINTS PR00107 Phosphocarrier protein signature 39 54 2.8E-19 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CB4_RS03815 5d26de9610dfdf1276351df2737d391c 86 PRINTS PR00107 Phosphocarrier protein signature 54 71 2.8E-19 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CB4_RS03815 5d26de9610dfdf1276351df2737d391c 86 SUPERFAMILY SSF55594 5 84 3.79E-26 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CB4_RS03815 5d26de9610dfdf1276351df2737d391c 86 Gene3D G3DSA:3.30.1340.10 3 86 2.1E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CB4_RS03815 5d26de9610dfdf1276351df2737d391c 86 Pfam PF00381 PTS HPr component phosphorylation site 4 83 4.6E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CB4_RS03815 5d26de9610dfdf1276351df2737d391c 86 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 3 82 2.8E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CB4_RS19380 139065e28144c1eb1dccbd321117032f 478 Gene3D G3DSA:3.40.605.10 1 267 2.7E-88 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS19380 139065e28144c1eb1dccbd321117032f 478 Pfam PF00171 Aldehyde dehydrogenase family 23 471 1.4E-162 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS19380 139065e28144c1eb1dccbd321117032f 478 SUPERFAMILY SSF53720 5 476 4.32E-154 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS19380 139065e28144c1eb1dccbd321117032f 478 Gene3D G3DSA:3.40.309.10 268 458 1.3E-63 T 29-03-2018 CB4_RS08060 c03c892876e537a746f3783c91d65e12 159 Gene3D G3DSA:3.30.310.120 52 155 7.5E-35 T 29-03-2018 CB4_RS08060 c03c892876e537a746f3783c91d65e12 159 SUPERFAMILY SSF111171 106 155 9.42E-17 T 29-03-2018 IPR015062 Protein of unknown function DUF1885 CB4_RS08060 c03c892876e537a746f3783c91d65e12 159 SUPERFAMILY SSF111171 5 90 1.27E-15 T 29-03-2018 IPR015062 Protein of unknown function DUF1885 CB4_RS08060 c03c892876e537a746f3783c91d65e12 159 Pfam PF08968 Domain of unknown function (DUF1885) 4 157 2.8E-51 T 29-03-2018 IPR015062 Protein of unknown function DUF1885 CB4_RS08060 c03c892876e537a746f3783c91d65e12 159 Gene3D G3DSA:1.20.5.850 4 50 1.2E-19 T 29-03-2018 CB4_RS02130 865d4788cf59e3a08ac391e1da01b3c8 508 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 33 484 2.4E-172 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS02130 865d4788cf59e3a08ac391e1da01b3c8 508 PIRSF PIRSF005690 20 499 2.3E-167 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS06375 ecb20a632d6ca92ed03678b03d5fa60e 744 Gene3D G3DSA:2.60.40.680 37 171 2.9E-16 T 29-03-2018 CB4_RS06375 ecb20a632d6ca92ed03678b03d5fa60e 744 Pfam PF00963 Cohesin domain 174 311 3.1E-16 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 CB4_RS06375 ecb20a632d6ca92ed03678b03d5fa60e 744 Pfam PF00963 Cohesin domain 43 167 3.7E-11 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 CB4_RS06375 ecb20a632d6ca92ed03678b03d5fa60e 744 SUPERFAMILY SSF49384 172 311 1.31E-19 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CB4_RS06375 ecb20a632d6ca92ed03678b03d5fa60e 744 Pfam PF00395 S-layer homology domain 573 612 2.6E-14 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS06375 ecb20a632d6ca92ed03678b03d5fa60e 744 Pfam PF00395 S-layer homology domain 690 733 6.8E-15 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS06375 ecb20a632d6ca92ed03678b03d5fa60e 744 Pfam PF00395 S-layer homology domain 632 673 8.4E-15 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS06375 ecb20a632d6ca92ed03678b03d5fa60e 744 Gene3D G3DSA:2.60.40.680 172 312 1.2E-19 T 29-03-2018 CB4_RS06375 ecb20a632d6ca92ed03678b03d5fa60e 744 SUPERFAMILY SSF49384 44 168 9.94E-14 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CB4_RS06105 0dd7d771c4545d46f575659a9563f2d1 87 PIRSF PIRSF037258 1 87 1.5E-41 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CB4_RS06105 0dd7d771c4545d46f575659a9563f2d1 87 Hamap MF_01507 UPF0297 protein . 1 85 27.502 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CB4_RS06105 0dd7d771c4545d46f575659a9563f2d1 87 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 82 2.1E-36 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CB4_RS16505 cf31930c9890d418e3b165883f88b16f 302 Gene3D G3DSA:3.20.20.370 76 300 2.1E-40 T 29-03-2018 CB4_RS16505 cf31930c9890d418e3b165883f88b16f 302 Pfam PF01522 Polysaccharide deacetylase 130 263 1.8E-18 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS16505 cf31930c9890d418e3b165883f88b16f 302 SUPERFAMILY SSF88713 90 275 2.78E-31 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS00985 92a49ca4b50021c4d0413c98254ffcb2 139 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 10 131 1.2E-26 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CB4_RS00985 92a49ca4b50021c4d0413c98254ffcb2 139 SUPERFAMILY SSF47188 7 131 1.83E-25 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CB4_RS00985 92a49ca4b50021c4d0413c98254ffcb2 139 ProSitePatterns PS00550 Hemerythrin family signature. 61 84 - T 29-03-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 CB4_RS00985 92a49ca4b50021c4d0413c98254ffcb2 139 Gene3D G3DSA:1.20.120.50 1 133 1.2E-28 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CB4_RS00985 92a49ca4b50021c4d0413c98254ffcb2 139 Pfam PF01814 Hemerythrin HHE cation binding domain 17 131 2.6E-8 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CB4_RS03110 60ef5d1db15ff6327cb77ba911f844b7 165 Pfam PF13404 AsnC-type helix-turn-helix domain 7 43 3.0E-7 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CB4_RS03110 60ef5d1db15ff6327cb77ba911f844b7 165 SUPERFAMILY SSF46785 4 60 7.03E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03110 60ef5d1db15ff6327cb77ba911f844b7 165 Gene3D G3DSA:3.30.70.920 55 152 7.0E-27 T 29-03-2018 CB4_RS03110 60ef5d1db15ff6327cb77ba911f844b7 165 Gene3D G3DSA:1.10.10.10 1 54 1.9E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03110 60ef5d1db15ff6327cb77ba911f844b7 165 SMART SM00344 4 113 4.2E-8 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CB4_RS03110 60ef5d1db15ff6327cb77ba911f844b7 165 Pfam PF01037 Lrp/AsnC ligand binding domain 70 143 7.5E-16 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CB4_RS03110 60ef5d1db15ff6327cb77ba911f844b7 165 SUPERFAMILY SSF54909 66 146 5.36E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CB4_RS01535 3731fb542912558fbfdfd7dd259ec06b 182 SMART SM00493 4 77 8.3E-8 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS01535 3731fb542912558fbfdfd7dd259ec06b 182 Pfam PF13662 Toprim domain 4 70 7.7E-6 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS01535 3731fb542912558fbfdfd7dd259ec06b 182 SUPERFAMILY SSF110455 2 112 1.7E-33 T 29-03-2018 CB4_RS01535 3731fb542912558fbfdfd7dd259ec06b 182 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 174 1.6E-51 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CB4_RS01535 3731fb542912558fbfdfd7dd259ec06b 182 Pfam PF13331 Domain of unknown function (DUF4093) 90 174 1.5E-27 T 29-03-2018 IPR025156 Ribonuclease M5, C-terminal domain CB4_RS01535 3731fb542912558fbfdfd7dd259ec06b 182 Gene3D G3DSA:3.40.1360.20 1 123 2.5E-22 T 29-03-2018 CB4_RS01535 3731fb542912558fbfdfd7dd259ec06b 182 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 176 30.305 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 SUPERFAMILY SSF51735 2 236 1.85E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 Gene3D G3DSA:3.40.50.720 1 212 1.4E-33 T 29-03-2018 CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.3E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.3E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.3E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.3E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.3E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 Pfam PF00106 short chain dehydrogenase 3 192 4.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS12875 d8c3bb426d352fef87f0b508f4dfbd38 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS06260 07e54f215f877cec431549ebf1ab0c17 349 SMART SM00471 126 262 8.5E-5 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS06260 07e54f215f877cec431549ebf1ab0c17 349 SUPERFAMILY SSF109604 121 290 3.14E-34 T 29-03-2018 CB4_RS06260 07e54f215f877cec431549ebf1ab0c17 349 Gene3D G3DSA:1.10.3210.10 99 295 8.2E-41 T 29-03-2018 CB4_RS06260 07e54f215f877cec431549ebf1ab0c17 349 Pfam PF01966 HD domain 131 253 2.2E-16 T 29-03-2018 IPR006674 HD domain CB4_RS17295 a166b31d07694607287811aac37a440e 808 SUPERFAMILY SSF56601 337 680 4.8E-104 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS17295 a166b31d07694607287811aac37a440e 808 SUPERFAMILY SSF56601 265 283 4.8E-104 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS17295 a166b31d07694607287811aac37a440e 808 SUPERFAMILY SSF53955 86 303 1.86E-63 T 29-03-2018 IPR023346 Lysozyme-like domain CB4_RS17295 a166b31d07694607287811aac37a440e 808 Pfam PF00905 Penicillin binding protein transpeptidase domain 403 640 8.6E-34 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CB4_RS17295 a166b31d07694607287811aac37a440e 808 Gene3D G3DSA:3.40.710.10 300 775 3.1E-96 T 29-03-2018 CB4_RS17295 a166b31d07694607287811aac37a440e 808 Pfam PF00912 Transglycosylase 95 279 7.3E-58 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CB4_RS17295 a166b31d07694607287811aac37a440e 808 Gene3D G3DSA:1.10.3810.10 87 296 1.3E-67 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CB4_RS03190 a219fa9762d6e7b9ad4841c417c18034 316 Pfam PF00535 Glycosyl transferase family 2 8 170 1.3E-26 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CB4_RS03190 a219fa9762d6e7b9ad4841c417c18034 316 Gene3D G3DSA:3.90.550.10 3 238 3.1E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS03190 a219fa9762d6e7b9ad4841c417c18034 316 SUPERFAMILY SSF53448 6 248 1.29E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS08725 5a350de374be04c6d92665cd72eb5503 366 Pfam PF13541 Subunit ChlI of Mg-chelatase 28 150 7.1E-43 T 29-03-2018 CB4_RS08725 5a350de374be04c6d92665cd72eb5503 366 Gene3D G3DSA:3.30.230.10 1 191 4.6E-37 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CB4_RS08725 5a350de374be04c6d92665cd72eb5503 366 SUPERFAMILY SSF52540 204 365 8.19E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08725 5a350de374be04c6d92665cd72eb5503 366 Gene3D G3DSA:3.40.50.300 192 365 7.8E-16 T 29-03-2018 CB4_RS08725 5a350de374be04c6d92665cd72eb5503 366 SUPERFAMILY SSF54211 17 173 6.83E-28 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CB4_RS08725 5a350de374be04c6d92665cd72eb5503 366 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 15 366 1.3E-113 T 29-03-2018 IPR004482 Mg chelatase-related protein CB4_RS08725 5a350de374be04c6d92665cd72eb5503 366 Pfam PF01078 Magnesium chelatase, subunit ChlI 205 366 1.4E-63 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain CB4_RS02035 9723e540c27affc6d2cf652906990a89 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CB4_RS02035 9723e540c27affc6d2cf652906990a89 429 Gene3D G3DSA:3.40.440.10 152 264 1.2E-27 T 29-03-2018 CB4_RS02035 9723e540c27affc6d2cf652906990a89 429 Gene3D G3DSA:3.40.440.10 1 151 3.3E-54 T 29-03-2018 CB4_RS02035 9723e540c27affc6d2cf652906990a89 429 SMART SM00788 3 422 3.1E-292 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CB4_RS02035 9723e540c27affc6d2cf652906990a89 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 210.797 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CB4_RS02035 9723e540c27affc6d2cf652906990a89 429 Pfam PF00709 Adenylosuccinate synthetase 4 420 7.6E-186 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CB4_RS02035 9723e540c27affc6d2cf652906990a89 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 4.0E-189 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CB4_RS02035 9723e540c27affc6d2cf652906990a89 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CB4_RS02035 9723e540c27affc6d2cf652906990a89 429 Gene3D G3DSA:3.90.170.10 265 429 7.4E-68 T 29-03-2018 CB4_RS02035 9723e540c27affc6d2cf652906990a89 429 SUPERFAMILY SSF52540 1 426 3.08E-175 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 PRINTS PR00046 Major sigma-70 factor signature 206 221 2.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 PRINTS PR00046 Major sigma-70 factor signature 87 100 2.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 PRINTS PR00046 Major sigma-70 factor signature 185 197 2.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 PRINTS PR00046 Major sigma-70 factor signature 221 232 2.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 9 239 1.2E-129 T 29-03-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 206 232 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 87 100 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 Gene3D G3DSA:1.10.601.10 31 131 2.5E-31 T 29-03-2018 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 SUPERFAMILY SSF88946 17 132 2.09E-35 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 Pfam PF04542 Sigma-70 region 2 63 132 6.3E-19 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 Pfam PF04545 Sigma-70, region 4 181 234 1.5E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 Gene3D G3DSA:1.10.1270.10 154 240 1.5E-21 T 29-03-2018 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 PIRSF PIRSF000770 9 240 1.7E-74 T 29-03-2018 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 SUPERFAMILY SSF88659 144 237 1.87E-22 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS08310 17cc127188c12e4e5046ae02a1826b75 240 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 60 235 6.9E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CB4_RS00410 dd94f5f08e871c99418b261af808b3db 208 Gene3D G3DSA:3.40.50.300 2 207 5.2E-54 T 29-03-2018 CB4_RS00410 dd94f5f08e871c99418b261af808b3db 208 Pfam PF00005 ABC transporter 22 154 1.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS00410 dd94f5f08e871c99418b261af808b3db 208 SUPERFAMILY SSF52540 5 205 8.54E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00410 dd94f5f08e871c99418b261af808b3db 208 SMART SM00382 22 204 2.7E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS00410 dd94f5f08e871c99418b261af808b3db 208 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS02315 4201c33927de1fa23e7d71c496936e62 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 277 2.2E-48 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS02315 4201c33927de1fa23e7d71c496936e62 293 Gene3D G3DSA:1.10.3470.10 1 282 1.3E-54 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS08305 313a1371fba3c60fdd74a3ac4c8de299 304 PIRSF PIRSF018571 1 298 6.2E-76 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CB4_RS08305 313a1371fba3c60fdd74a3ac4c8de299 304 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 1 294 1.5E-75 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CB4_RS08305 313a1371fba3c60fdd74a3ac4c8de299 304 Pfam PF03419 Sporulation factor SpoIIGA 2 294 1.3E-77 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CB4_RS20340 7a9f6d0512e93e4cedebf19ae4f78339 84 Pfam PF11127 Protein of unknown function (DUF2892) 1 66 6.8E-14 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 CB4_RS05960 10babc72c1215c63f7df307a94449330 376 Pfam PF01702 Queuine tRNA-ribosyltransferase 131 364 5.1E-94 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CB4_RS05960 10babc72c1215c63f7df307a94449330 376 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 370 8.0E-171 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CB4_RS05960 10babc72c1215c63f7df307a94449330 376 Gene3D G3DSA:3.20.20.105 1 373 5.1E-165 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CB4_RS05960 10babc72c1215c63f7df307a94449330 376 SUPERFAMILY SSF51713 3 368 6.28E-165 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CB4_RS05960 10babc72c1215c63f7df307a94449330 376 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 3 367 58.466 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CB4_RS05960 10babc72c1215c63f7df307a94449330 376 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 5 370 1.8E-181 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CB4_RS06735 0cb03aa63131a3d75c754562f65396cf 149 SUPERFAMILY SSF55811 5 135 8.94E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CB4_RS06735 0cb03aa63131a3d75c754562f65396cf 149 ProDom PD037294 PEPTIDE ACMNPV ORF38 ORF ORF_59 ORF61 ORF7 PXORF52 ORF-30 ORF79 31 59 0.002 T 29-03-2018 CB4_RS06735 0cb03aa63131a3d75c754562f65396cf 149 PRINTS PR00502 NUDIX hydrolase family signature 32 46 9.1E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CB4_RS06735 0cb03aa63131a3d75c754562f65396cf 149 PRINTS PR00502 NUDIX hydrolase family signature 46 61 9.1E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CB4_RS06735 0cb03aa63131a3d75c754562f65396cf 149 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CB4_RS06735 0cb03aa63131a3d75c754562f65396cf 149 Pfam PF00293 NUDIX domain 6 120 1.0E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CB4_RS06735 0cb03aa63131a3d75c754562f65396cf 149 Gene3D G3DSA:3.90.79.10 3 145 2.2E-23 T 29-03-2018 CB4_RS07790 3ffc73a82a88049d6c11124fa087345a 433 Pfam PF13183 4Fe-4S dicluster domain 18 85 1.9E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CB4_RS07790 3ffc73a82a88049d6c11124fa087345a 433 Gene3D G3DSA:1.10.1060.10 1 107 5.5E-20 T 29-03-2018 CB4_RS07790 3ffc73a82a88049d6c11124fa087345a 433 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 20 31 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS07790 3ffc73a82a88049d6c11124fa087345a 433 Pfam PF02754 Cysteine-rich domain 191 273 1.0E-16 T 29-03-2018 IPR004017 Cysteine-rich domain CB4_RS07790 3ffc73a82a88049d6c11124fa087345a 433 Pfam PF02754 Cysteine-rich domain 320 405 2.7E-15 T 29-03-2018 IPR004017 Cysteine-rich domain CB4_RS07790 3ffc73a82a88049d6c11124fa087345a 433 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CB4_RS07790 3ffc73a82a88049d6c11124fa087345a 433 SUPERFAMILY SSF54862 12 110 8.79E-18 T 29-03-2018 CB4_RS07790 3ffc73a82a88049d6c11124fa087345a 433 PIRSF PIRSF000139 1 432 2.9E-125 T 29-03-2018 CB4_RS00260 22faf1536ffdf22075b2499918e7206f 466 Pfam PF00324 Amino acid permease 16 397 1.4E-38 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CB4_RS00260 22faf1536ffdf22075b2499918e7206f 466 PIRSF PIRSF006060 1 457 6.4E-79 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS03175 71d9129dcdfd6d19ad58226baf95724f 172 Pfam PF13242 HAD-hyrolase-like 108 148 1.4E-8 T 29-03-2018 CB4_RS03175 71d9129dcdfd6d19ad58226baf95724f 172 PIRSF PIRSF004682 1 168 8.7E-59 T 29-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 CB4_RS03175 71d9129dcdfd6d19ad58226baf95724f 172 Gene3D G3DSA:3.40.50.1000 1 155 4.6E-26 T 29-03-2018 IPR023214 HAD-like domain CB4_RS03175 71d9129dcdfd6d19ad58226baf95724f 172 TIGRFAM TIGR00213 GmhB_yaeD: D,D-heptose 1,7-bisphosphate phosphatase 3 153 2.1E-57 T 29-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 CB4_RS03175 71d9129dcdfd6d19ad58226baf95724f 172 SUPERFAMILY SSF56784 1 149 7.11E-45 T 29-03-2018 IPR023214 HAD-like domain CB4_RS03175 71d9129dcdfd6d19ad58226baf95724f 172 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 149 1.8E-32 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CB4_RS03175 71d9129dcdfd6d19ad58226baf95724f 172 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 149 1.7E-39 T 29-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CB4_RS03965 e7eaefe7e1daf5498b5d04d27a2712d8 153 Pfam PF07238 PilZ domain 7 104 1.5E-7 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CB4_RS03965 e7eaefe7e1daf5498b5d04d27a2712d8 153 Gene3D G3DSA:2.40.10.220 5 116 2.1E-10 T 29-03-2018 CB4_RS03965 e7eaefe7e1daf5498b5d04d27a2712d8 153 SUPERFAMILY SSF141371 5 110 2.16E-6 T 29-03-2018 CB4_RS11125 4eea1bcb7e8f170030bcf9feed25af26 346 Pfam PF11104 Type IV pilus assembly protein PilM; 32 342 4.1E-14 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM CB4_RS11125 4eea1bcb7e8f170030bcf9feed25af26 346 Gene3D G3DSA:3.30.420.40 1 162 1.0E-4 T 29-03-2018 CB4_RS15825 4e2c597c866afafcbe50abd721b5f077 119 SUPERFAMILY SSF52091 1 116 7.46E-30 T 29-03-2018 IPR002645 STAS domain CB4_RS15825 4e2c597c866afafcbe50abd721b5f077 119 Pfam PF11964 SpoIIAA-like 12 116 5.7E-20 T 29-03-2018 IPR021866 SpoIIAA-like CB4_RS15825 4e2c597c866afafcbe50abd721b5f077 119 Gene3D G3DSA:3.40.50.10600 1 118 9.5E-20 T 29-03-2018 CB4_RS18895 0c563a26bf92980bb9993a1785d65757 632 SUPERFAMILY SSF52540 68 179 3.24E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS18895 0c563a26bf92980bb9993a1785d65757 632 SUPERFAMILY SSF52540 232 364 3.24E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS18895 0c563a26bf92980bb9993a1785d65757 632 SUPERFAMILY SSF52540 406 445 3.24E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS18895 0c563a26bf92980bb9993a1785d65757 632 Pfam PF06798 PrkA serine protein kinase C-terminal domain 376 625 6.3E-94 T 29-03-2018 IPR010650 PrkA C-terminal domain CB4_RS18895 0c563a26bf92980bb9993a1785d65757 632 PIRSF PIRSF000549 1 632 2.1E-259 T 29-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 CB4_RS18895 0c563a26bf92980bb9993a1785d65757 632 Pfam PF08298 PrkA AAA domain 22 370 5.0E-146 T 29-03-2018 IPR013153 PrkA AAA domain CB4_RS18895 0c563a26bf92980bb9993a1785d65757 632 Gene3D G3DSA:3.40.50.300 43 367 2.7E-7 T 29-03-2018 CB4_RS18895 0c563a26bf92980bb9993a1785d65757 632 SMART SM00763 21 372 5.1E-191 T 29-03-2018 IPR013153 PrkA AAA domain CB4_RS03055 18c677a463f4193ece456f6bef50586c 258 Pfam PF08680 TATA-box binding 66 257 2.8E-37 T 29-03-2018 IPR014794 TATA-box binding CB4_RS03055 18c677a463f4193ece456f6bef50586c 258 Gene3D G3DSA:3.30.360.40 187 257 9.3E-25 T 29-03-2018 CB4_RS03055 18c677a463f4193ece456f6bef50586c 258 SUPERFAMILY SSF143842 44 254 7.98E-33 T 29-03-2018 IPR014794 TATA-box binding CB4_RS03055 18c677a463f4193ece456f6bef50586c 258 Gene3D G3DSA:3.30.2030.10 45 179 1.4E-8 T 29-03-2018 CB4_RS02180 a2ad7beed2021a23abbcc754e8598745 130 Pfam PF05154 TM2 domain 25 69 1.6E-10 T 29-03-2018 IPR007829 TM2 domain CB4_RS08545 296734131b3f51d91d6e62a48e87bfdf 288 Gene3D G3DSA:3.40.50.10170 1 155 1.3E-52 T 29-03-2018 CB4_RS08545 296734131b3f51d91d6e62a48e87bfdf 288 Gene3D G3DSA:3.30.1180.10 156 283 1.2E-34 T 29-03-2018 CB4_RS08545 296734131b3f51d91d6e62a48e87bfdf 288 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 282 1.0E-94 T 29-03-2018 IPR003797 DegV CB4_RS08545 296734131b3f51d91d6e62a48e87bfdf 288 Pfam PF02645 Uncharacterised protein, DegV family COG1307 4 283 2.3E-84 T 29-03-2018 IPR003797 DegV CB4_RS08545 296734131b3f51d91d6e62a48e87bfdf 288 SUPERFAMILY SSF82549 1 284 5.23E-84 T 29-03-2018 CB4_RS15010 0ab89e43b55b313274b8ceeb3332e0fc 285 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 212 2.6E-66 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS15010 0ab89e43b55b313274b8ceeb3332e0fc 285 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 217 271 6.4E-26 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CB4_RS15010 0ab89e43b55b313274b8ceeb3332e0fc 285 PIRSF PIRSF006483 1 279 1.2E-95 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS08690 1b3c98d9c02a01543ce11df3392e383e 115 Pfam PF01245 Ribosomal protein L19 4 112 6.2E-52 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08690 1b3c98d9c02a01543ce11df3392e383e 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 32.217 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08690 1b3c98d9c02a01543ce11df3392e383e 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 3.2E-51 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08690 1b3c98d9c02a01543ce11df3392e383e 115 PIRSF PIRSF002191 1 115 9.1E-51 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08690 1b3c98d9c02a01543ce11df3392e383e 115 SUPERFAMILY SSF50104 2 114 1.4E-47 T 29-03-2018 IPR008991 Translation protein SH3-like domain CB4_RS08690 1b3c98d9c02a01543ce11df3392e383e 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08690 1b3c98d9c02a01543ce11df3392e383e 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08690 1b3c98d9c02a01543ce11df3392e383e 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08690 1b3c98d9c02a01543ce11df3392e383e 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS18525 b5f1d481bd882edfc3c0d64895c19917 445 Gene3D G3DSA:3.30.1490.20 209 283 2.1E-10 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS18525 b5f1d481bd882edfc3c0d64895c19917 445 Pfam PF14398 YheC/D like ATP-grasp 179 427 3.7E-76 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CB4_RS18525 b5f1d481bd882edfc3c0d64895c19917 445 Gene3D G3DSA:3.30.470.20 284 414 7.6E-12 T 29-03-2018 CB4_RS18525 b5f1d481bd882edfc3c0d64895c19917 445 SUPERFAMILY SSF56059 206 409 5.55E-11 T 29-03-2018 CB4_RS05445 c0915c6b0cf7ee61b741961a49a1c286 160 Pfam PF14221 Domain of unknown function (DUF4330) 15 122 6.0E-7 T 29-03-2018 IPR025480 Protein of unknown function DUF4330 CB4_RS06215 1f051d2418858a6a7bd47991f988630b 229 Gene3D G3DSA:3.40.50.2300 2 124 1.6E-34 T 29-03-2018 CB4_RS06215 1f051d2418858a6a7bd47991f988630b 229 Gene3D G3DSA:1.10.10.10 125 228 1.8E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS06215 1f051d2418858a6a7bd47991f988630b 229 SMART SM00448 2 112 1.1E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS06215 1f051d2418858a6a7bd47991f988630b 229 SMART SM00862 149 224 7.2E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS06215 1f051d2418858a6a7bd47991f988630b 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 1.0E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CB4_RS06215 1f051d2418858a6a7bd47991f988630b 229 Pfam PF00072 Response regulator receiver domain 4 112 8.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS06215 1f051d2418858a6a7bd47991f988630b 229 SUPERFAMILY SSF46894 128 224 1.13E-29 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS06215 1f051d2418858a6a7bd47991f988630b 229 SUPERFAMILY SSF52172 3 125 1.71E-39 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS20650 54b4f9f2031bbbd1de5eb5728365369b 126 Gene3D G3DSA:3.90.470.20 1 126 1.5E-36 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS20650 54b4f9f2031bbbd1de5eb5728365369b 126 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 125 1.3E-32 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CB4_RS20650 54b4f9f2031bbbd1de5eb5728365369b 126 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 125 2.6E-31 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CB4_RS20650 54b4f9f2031bbbd1de5eb5728365369b 126 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 125 5.0E-23 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CB4_RS20650 54b4f9f2031bbbd1de5eb5728365369b 126 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 99 3.3E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS20650 54b4f9f2031bbbd1de5eb5728365369b 126 SUPERFAMILY SSF56214 1 125 8.5E-31 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS20650 54b4f9f2031bbbd1de5eb5728365369b 126 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 126 25.242 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CB4_RS05115 fe1c2bf0c4cc7ee2136ec8fbf75783ce 267 Gene3D G3DSA:3.40.50.300 1 265 3.6E-59 T 29-03-2018 CB4_RS05115 fe1c2bf0c4cc7ee2136ec8fbf75783ce 267 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 252 5.6E-12 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CB4_RS05115 fe1c2bf0c4cc7ee2136ec8fbf75783ce 267 SMART SM00382 30 230 2.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS05115 fe1c2bf0c4cc7ee2136ec8fbf75783ce 267 Pfam PF00005 ABC transporter 22 181 4.6E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS05115 fe1c2bf0c4cc7ee2136ec8fbf75783ce 267 SUPERFAMILY SSF52540 5 253 3.17E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00755 8efa52a5d074e5eb18b8a7ac72d35fe3 237 SMART SM00646 114 225 1.3E-32 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CB4_RS00755 8efa52a5d074e5eb18b8a7ac72d35fe3 237 Gene3D G3DSA:3.40.630.40 32 229 9.4E-58 T 29-03-2018 CB4_RS00755 8efa52a5d074e5eb18b8a7ac72d35fe3 237 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 41 225 3.1E-50 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CB4_RS00755 8efa52a5d074e5eb18b8a7ac72d35fe3 237 SUPERFAMILY SSF53187 39 228 2.51E-53 T 29-03-2018 CB4_RS00755 8efa52a5d074e5eb18b8a7ac72d35fe3 237 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 39 227 2.4E-77 T 29-03-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD CB4_RS14340 bb9fb14a474229125edb0910034bfd4f 127 Gene3D G3DSA:1.20.120.540 22 97 2.0E-4 T 29-03-2018 IPR027378 Cyclic nucleotide-regulated ion channel, N-terminal domain Reactome: R-HSA-159418|Reactome: R-HSA-879518 CB4_RS05150 5e08a38dbe51bc737b0c243e4f1cba8a 480 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CB4_RS05150 5e08a38dbe51bc737b0c243e4f1cba8a 480 Gene3D G3DSA:3.40.605.10 1 266 1.7E-106 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS05150 5e08a38dbe51bc737b0c243e4f1cba8a 480 Pfam PF00171 Aldehyde dehydrogenase family 13 476 4.9E-180 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS05150 5e08a38dbe51bc737b0c243e4f1cba8a 480 SUPERFAMILY SSF53720 5 478 5.89E-174 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS05150 5e08a38dbe51bc737b0c243e4f1cba8a 480 Gene3D G3DSA:3.40.309.10 267 462 5.2E-74 T 29-03-2018 CB4_RS09975 9670ec32ada1ffe81ec793275da5518a 143 Pfam PF13673 Acetyltransferase (GNAT) domain 11 140 4.2E-20 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS09975 9670ec32ada1ffe81ec793275da5518a 143 SUPERFAMILY SSF55729 4 140 9.78E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS09975 9670ec32ada1ffe81ec793275da5518a 143 Gene3D G3DSA:3.40.630.30 2 142 2.8E-35 T 29-03-2018 CB4_RS14595 085f3038ee05ff11f4ef764a47a8ef89 246 Gene3D G3DSA:3.40.50.720 33 203 9.1E-11 T 29-03-2018 CB4_RS14595 085f3038ee05ff11f4ef764a47a8ef89 246 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 34 125 8.8E-11 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CB4_RS14595 085f3038ee05ff11f4ef764a47a8ef89 246 SUPERFAMILY SSF51735 33 235 4.78E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS05470 cef2d859963048182ad3e1641d02480a 369 Pfam PF04230 Polysaccharide pyruvyl transferase 14 297 6.7E-47 T 29-03-2018 IPR007345 Polysaccharide pyruvyl transferase CB4_RS05470 cef2d859963048182ad3e1641d02480a 369 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 3 313 5.7E-87 T 29-03-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB CB4_RS05470 cef2d859963048182ad3e1641d02480a 369 Gene3D G3DSA:3.40.50.2000 177 341 3.2E-6 T 29-03-2018 CB4_RS03400 9d9ec806c4f999feeaec83eec420d908 169 Gene3D G3DSA:1.20.58.300 4 138 3.0E-19 T 29-03-2018 CB4_RS03400 9d9ec806c4f999feeaec83eec420d908 169 Pfam PF05130 FlgN protein 4 150 2.1E-17 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CB4_RS03400 9d9ec806c4f999feeaec83eec420d908 169 SUPERFAMILY SSF140566 8 136 2.88E-12 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CB4_RS20070 81c78b6451df4d4ff20b3220cc25f659 216 Pfam PF00892 EamA-like transporter family 78 210 8.8E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS20070 81c78b6451df4d4ff20b3220cc25f659 216 SUPERFAMILY SSF103481 121 211 2.22E-14 T 29-03-2018 CB4_RS05120 306ec8a2fda240aeddcb1f34366b184c 245 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 223 242 9.7E-5 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CB4_RS05120 306ec8a2fda240aeddcb1f34366b184c 245 Pfam PF00005 ABC transporter 22 170 3.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS05120 306ec8a2fda240aeddcb1f34366b184c 245 SUPERFAMILY SSF52540 5 242 2.15E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS05120 306ec8a2fda240aeddcb1f34366b184c 245 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS05120 306ec8a2fda240aeddcb1f34366b184c 245 Gene3D G3DSA:3.40.50.300 3 244 3.7E-61 T 29-03-2018 CB4_RS05120 306ec8a2fda240aeddcb1f34366b184c 245 SMART SM00382 31 220 1.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS19450 14a05ec40042eb8d1c9f016c8e8060eb 366 Pfam PF07833 Copper amine oxidase N-terminal domain 96 181 1.8E-17 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS19450 14a05ec40042eb8d1c9f016c8e8060eb 366 Gene3D G3DSA:2.40.50.140 279 364 2.5E-11 T 29-03-2018 CB4_RS19450 14a05ec40042eb8d1c9f016c8e8060eb 366 Gene3D G3DSA:2.40.50.140 181 268 4.3E-7 T 29-03-2018 CB4_RS19450 14a05ec40042eb8d1c9f016c8e8060eb 366 SUPERFAMILY SSF55383 98 180 3.66E-15 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS19450 14a05ec40042eb8d1c9f016c8e8060eb 366 Gene3D G3DSA:3.30.457.10 99 179 6.6E-17 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS17200 1d24f91e72f7152ab59870ac3fedca5a 117 Pfam PF04341 Protein of unknown function, DUF485 27 110 2.6E-23 T 29-03-2018 IPR007436 Protein of unknown function DUF485 CB4_RS06245 78a1a67ca1ffd635c3478a43da63e248 406 Gene3D G3DSA:3.40.630.30 148 291 5.5E-39 T 29-03-2018 CB4_RS06245 78a1a67ca1ffd635c3478a43da63e248 406 Gene3D G3DSA:3.30.1050.10 292 400 9.0E-28 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CB4_RS06245 78a1a67ca1ffd635c3478a43da63e248 406 SUPERFAMILY SSF55718 302 406 2.35E-28 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CB4_RS06245 78a1a67ca1ffd635c3478a43da63e248 406 SUPERFAMILY SSF55729 11 298 3.33E-77 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS06245 78a1a67ca1ffd635c3478a43da63e248 406 Pfam PF13527 Acetyltransferase (GNAT) domain 12 145 5.9E-42 T 29-03-2018 CB4_RS06245 78a1a67ca1ffd635c3478a43da63e248 406 Gene3D G3DSA:3.40.630.30 1 147 8.7E-11 T 29-03-2018 CB4_RS06245 78a1a67ca1ffd635c3478a43da63e248 406 Pfam PF13530 Sterol carrier protein domain 190 402 9.6E-56 T 29-03-2018 IPR025559 Enhanced intracellular survival protein domain CB4_RS02080 7b5f4c82e220c6840e5499bd29c820ac 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 31.044 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS02080 7b5f4c82e220c6840e5499bd29c820ac 159 Gene3D G3DSA:3.40.1280.10 1 159 2.5E-63 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CB4_RS02080 7b5f4c82e220c6840e5499bd29c820ac 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 1.1E-69 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS02080 7b5f4c82e220c6840e5499bd29c820ac 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 2.1E-60 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS02080 7b5f4c82e220c6840e5499bd29c820ac 159 SUPERFAMILY SSF75217 1 157 2.03E-61 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CB4_RS02080 7b5f4c82e220c6840e5499bd29c820ac 159 PIRSF PIRSF004505 1 159 6.9E-53 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CB4_RS00845 6b0f13d9ee69d2a99be53498c1dc8163 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS00845 6b0f13d9ee69d2a99be53498c1dc8163 248 SUPERFAMILY SSF55920 1 247 2.22E-92 T 29-03-2018 IPR000994 Peptidase M24 CB4_RS00845 6b0f13d9ee69d2a99be53498c1dc8163 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 42.323 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS00845 6b0f13d9ee69d2a99be53498c1dc8163 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.5E-100 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS00845 6b0f13d9ee69d2a99be53498c1dc8163 248 Pfam PF00557 Metallopeptidase family M24 12 239 1.6E-55 T 29-03-2018 IPR000994 Peptidase M24 CB4_RS00845 6b0f13d9ee69d2a99be53498c1dc8163 248 Gene3D G3DSA:3.90.230.10 1 248 7.6E-86 T 29-03-2018 CB4_RS00845 6b0f13d9ee69d2a99be53498c1dc8163 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 2.1E-24 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS00845 6b0f13d9ee69d2a99be53498c1dc8163 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 2.1E-24 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS00845 6b0f13d9ee69d2a99be53498c1dc8163 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 2.1E-24 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS00845 6b0f13d9ee69d2a99be53498c1dc8163 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 2.1E-24 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CB4_RS19325 5d23381e9ae5ef9f73a81c213e621352 210 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 205 28.962 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CB4_RS19325 5d23381e9ae5ef9f73a81c213e621352 210 Pfam PF02525 Flavodoxin-like fold 3 203 3.7E-47 T 29-03-2018 IPR003680 Flavodoxin-like fold CB4_RS19325 5d23381e9ae5ef9f73a81c213e621352 210 Gene3D G3DSA:3.40.50.360 3 210 3.2E-41 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS19325 5d23381e9ae5ef9f73a81c213e621352 210 SUPERFAMILY SSF52218 1 208 2.58E-49 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS08075 c1fa99620f2e003fa2e0beafc1dc58b4 45 Pfam PF13790 SR1 protein 9 43 4.1E-13 T 29-03-2018 IPR025236 SR1 protein CB4_RS13015 e8b8279077c00804f060ba2784769be1 308 Gene3D G3DSA:3.60.15.10 18 308 4.0E-55 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS13015 e8b8279077c00804f060ba2784769be1 308 Pfam PF12706 Beta-lactamase superfamily domain 75 264 5.6E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS13015 e8b8279077c00804f060ba2784769be1 308 PIRSF PIRSF038896 6 306 1.6E-94 T 29-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 CB4_RS13015 e8b8279077c00804f060ba2784769be1 308 SUPERFAMILY SSF56281 57 271 4.19E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS00015 5b9f09a20f4aba4ca41d9a1e939a4226 475 TIGRFAM TIGR00238 TIGR00238: KamA family protein 24 351 7.8E-142 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CB4_RS00015 5b9f09a20f4aba4ca41d9a1e939a4226 475 Pfam PF04055 Radical SAM superfamily 139 286 6.4E-7 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS00015 5b9f09a20f4aba4ca41d9a1e939a4226 475 SUPERFAMILY SSF102114 123 369 3.53E-34 T 29-03-2018 CB4_RS00015 5b9f09a20f4aba4ca41d9a1e939a4226 475 Gene3D G3DSA:3.20.20.70 125 334 1.8E-20 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS00015 5b9f09a20f4aba4ca41d9a1e939a4226 475 Pfam PF12544 Lysine-2,3-aminomutase 330 455 4.7E-58 T 29-03-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain CB4_RS00015 5b9f09a20f4aba4ca41d9a1e939a4226 475 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 30 435 2.9E-190 T 29-03-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 CB4_RS11765 e105a61cd0d84e35ea5c86b06a7e7ef7 753 Gene3D G3DSA:2.60.120.260 230 389 6.2E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS11765 e105a61cd0d84e35ea5c86b06a7e7ef7 753 Pfam PF00754 F5/8 type C domain 248 378 2.2E-10 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CB4_RS11765 e105a61cd0d84e35ea5c86b06a7e7ef7 753 Gene3D G3DSA:2.60.120.260 12 138 3.0E-15 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS11765 e105a61cd0d84e35ea5c86b06a7e7ef7 753 SUPERFAMILY SSF49785 251 386 8.51E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like CB4_RS01965 bc9d0e97b724954e95d0033135333459 385 PIRSF PIRSF005572 1 384 2.8E-60 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CB4_RS01965 bc9d0e97b724954e95d0033135333459 385 SUPERFAMILY SSF53383 3 381 7.24E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS01965 bc9d0e97b724954e95d0033135333459 385 TIGRFAM TIGR01977 am_tr_V_EF2568: cysteine desulfurase family protein 4 379 3.0E-151 T 29-03-2018 IPR010969 Cysteine desulfurase-related, unknown function CB4_RS01965 bc9d0e97b724954e95d0033135333459 385 Gene3D G3DSA:3.90.1150.10 256 379 8.8E-39 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS01965 bc9d0e97b724954e95d0033135333459 385 Pfam PF00266 Aminotransferase class-V 4 372 7.8E-92 T 29-03-2018 IPR000192 Aminotransferase class V domain CB4_RS01965 bc9d0e97b724954e95d0033135333459 385 Gene3D G3DSA:3.40.640.10 15 255 1.1E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS10310 71bfaded6719fcb5291e5d570ac46962 332 Gene3D G3DSA:2.130.10.10 27 153 7.9E-11 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS10310 71bfaded6719fcb5291e5d570ac46962 332 Gene3D G3DSA:2.130.10.10 154 316 1.4E-18 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS10310 71bfaded6719fcb5291e5d570ac46962 332 SUPERFAMILY SSF51004 35 323 9.42E-39 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CB4_RS18065 f340d602da03dbe784cc131e14771571 525 Gene3D G3DSA:3.40.50.980 175 333 8.4E-43 T 29-03-2018 CB4_RS18065 f340d602da03dbe784cc131e14771571 525 SUPERFAMILY SSF56801 4 521 1.03E-151 T 29-03-2018 CB4_RS18065 f340d602da03dbe784cc131e14771571 525 Pfam PF00501 AMP-binding enzyme 10 423 1.1E-102 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CB4_RS18065 f340d602da03dbe784cc131e14771571 525 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 509 1.1E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CB4_RS18065 f340d602da03dbe784cc131e14771571 525 Gene3D G3DSA:3.30.300.30 418 525 9.3E-27 T 29-03-2018 CB4_RS18065 f340d602da03dbe784cc131e14771571 525 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 29-03-2018 IPR020845 AMP-binding, conserved site CB4_RS18065 f340d602da03dbe784cc131e14771571 525 Gene3D G3DSA:3.40.50.980 1 174 4.2E-47 T 29-03-2018 CB4_RS18065 f340d602da03dbe784cc131e14771571 525 Gene3D G3DSA:2.30.38.10 334 417 2.9E-23 T 29-03-2018 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 SUPERFAMILY SSF68912 3 48 2.71E-11 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 Gene3D G3DSA:3.40.50.300 106 366 1.8E-51 T 29-03-2018 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 SMART SM00357 54 118 8.5E-21 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 SUPERFAMILY SSF50249 51 125 1.29E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 TIGRFAM TIGR00767 rho: transcription termination factor Rho 4 410 7.7E-201 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 Gene3D G3DSA:2.40.50.140 51 105 3.6E-29 T 29-03-2018 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 156 360 8.4E-20 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 SMART SM00382 167 361 2.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 Pfam PF07498 Rho termination factor, N-terminal domain 7 49 2.4E-15 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 Gene3D G3DSA:1.10.720.10 1 45 7.0E-16 T 29-03-2018 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 Pfam PF07497 Rho termination factor, RNA-binding domain 53 125 1.2E-31 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 SMART SM00959 7 49 1.2E-14 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 221.769 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CB4_RS02825 e68fe3fb2a6c5929f5b73c001bf60e63 424 SUPERFAMILY SSF52540 90 368 1.32E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00415 8eb55a1267f2901ca87798fe80b70e98 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 218 8.7E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS00415 8eb55a1267f2901ca87798fe80b70e98 229 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 11 218 1.2E-80 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CB4_RS00415 8eb55a1267f2901ca87798fe80b70e98 229 Gene3D G3DSA:1.10.3720.10 6 226 1.4E-41 T 29-03-2018 CB4_RS00415 8eb55a1267f2901ca87798fe80b70e98 229 SUPERFAMILY SSF161098 7 217 1.23E-53 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS00430 c55d662c1b60103fd441d8790a8d36ba 156 SUPERFAMILY SSF55826 4 150 3.66E-41 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CB4_RS00430 c55d662c1b60103fd441d8790a8d36ba 156 Pfam PF04073 Aminoacyl-tRNA editing domain 24 143 1.1E-32 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CB4_RS00430 c55d662c1b60103fd441d8790a8d36ba 156 Gene3D G3DSA:3.90.960.10 1 152 1.1E-38 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CB4_RS10090 0441d7ca35bd640265d3ef597e28c571 436 Gene3D G3DSA:3.90.350.10 97 323 8.6E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CB4_RS10090 0441d7ca35bd640265d3ef597e28c571 436 Pfam PF01609 Transposase DDE domain 109 339 9.4E-17 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CB4_RS10090 0441d7ca35bd640265d3ef597e28c571 436 SUPERFAMILY SSF53098 105 339 3.11E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS05425 0441d7ca35bd640265d3ef597e28c571 436 Gene3D G3DSA:3.90.350.10 97 323 8.6E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CB4_RS05425 0441d7ca35bd640265d3ef597e28c571 436 Pfam PF01609 Transposase DDE domain 109 339 9.4E-17 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CB4_RS05425 0441d7ca35bd640265d3ef597e28c571 436 SUPERFAMILY SSF53098 105 339 3.11E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS15515 452eaac6ea75e5649dd1c38cdcb5d5c1 564 Pfam PF03354 Phage Terminase 80 544 5.4E-97 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CB4_RS08285 a17288228d9428c59b8a06bbabe239b5 120 PIRSF PIRSF018579 1 113 8.7E-45 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 CB4_RS08285 a17288228d9428c59b8a06bbabe239b5 120 Pfam PF06947 Protein of unknown function (DUF1290) 22 107 3.7E-35 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 CB4_RS01710 ff74d09fa918767aa43097b041ea2070 256 Pfam PF09992 Phosphodiester glycosidase 84 252 6.6E-26 T 29-03-2018 IPR018711 Phosphodiester glycosidase CB4_RS00065 ab22042a9795224526a04c164dbae17e 784 SUPERFAMILY SSF52540 499 772 5.47E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00065 ab22042a9795224526a04c164dbae17e 784 SUPERFAMILY SSF52540 203 363 5.47E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS00065 ab22042a9795224526a04c164dbae17e 784 Pfam PF13538 UvrD-like helicase C-terminal domain 717 761 4.2E-9 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain CB4_RS00065 ab22042a9795224526a04c164dbae17e 784 Pfam PF13245 AAA domain 216 586 5.9E-11 T 29-03-2018 CB4_RS00065 ab22042a9795224526a04c164dbae17e 784 Gene3D G3DSA:3.40.50.300 210 607 1.3E-33 T 29-03-2018 CB4_RS00065 ab22042a9795224526a04c164dbae17e 784 Gene3D G3DSA:3.40.50.300 611 783 1.4E-31 T 29-03-2018 CB4_RS08165 0f49212d44889a4f5095b36aa8e7560a 302 SUPERFAMILY SSF47807 189 301 7.33E-29 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CB4_RS08165 0f49212d44889a4f5095b36aa8e7560a 302 Gene3D G3DSA:1.10.150.20 203 280 4.7E-25 T 29-03-2018 CB4_RS08165 0f49212d44889a4f5095b36aa8e7560a 302 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 189 278 2.2E-27 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CB4_RS08165 0f49212d44889a4f5095b36aa8e7560a 302 SUPERFAMILY SSF88723 16 188 9.32E-46 T 29-03-2018 IPR029060 PIN domain-like CB4_RS08165 0f49212d44889a4f5095b36aa8e7560a 302 SMART SM00279 191 226 5.5E-17 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CB4_RS08165 0f49212d44889a4f5095b36aa8e7560a 302 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 18 181 7.4E-49 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CB4_RS08165 0f49212d44889a4f5095b36aa8e7560a 302 Gene3D G3DSA:3.40.50.1010 16 202 3.1E-61 T 29-03-2018 IPR029060 PIN domain-like CB4_RS08165 0f49212d44889a4f5095b36aa8e7560a 302 SMART SM00475 14 279 1.8E-106 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CB4_RS13870 11f19e87a80ea5f293ac4b236b954101 269 SUPERFAMILY SSF53807 5 258 2.43E-54 T 29-03-2018 CB4_RS13870 11f19e87a80ea5f293ac4b236b954101 269 Gene3D G3DSA:3.40.50.1980 3 113 4.6E-26 T 29-03-2018 CB4_RS13870 11f19e87a80ea5f293ac4b236b954101 269 Gene3D G3DSA:3.40.50.1980 114 264 1.2E-27 T 29-03-2018 CB4_RS13870 11f19e87a80ea5f293ac4b236b954101 269 Pfam PF01497 Periplasmic binding protein 23 212 1.3E-22 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CB4_RS01800 2c91d283397af28c3e4e780d0ad88358 306 Gene3D G3DSA:3.40.50.1400 108 234 3.6E-29 T 29-03-2018 CB4_RS01800 2c91d283397af28c3e4e780d0ad88358 306 Gene3D G3DSA:3.40.50.1400 1 107 4.0E-29 T 29-03-2018 CB4_RS01800 2c91d283397af28c3e4e780d0ad88358 306 SUPERFAMILY SSF53800 1 247 1.74E-56 T 29-03-2018 CB4_RS01800 2c91d283397af28c3e4e780d0ad88358 306 Pfam PF01903 CbiX 9 114 1.2E-28 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CB4_RS01800 2c91d283397af28c3e4e780d0ad88358 306 Pfam PF01903 CbiX 137 240 3.9E-24 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CB4_RS05430 d4f886e1d7c39827feaef281f96232fa 352 Pfam PF13439 Glycosyltransferase Family 4 17 159 1.1E-16 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CB4_RS05430 d4f886e1d7c39827feaef281f96232fa 352 Gene3D G3DSA:3.40.50.2000 8 169 6.1E-8 T 29-03-2018 CB4_RS05430 d4f886e1d7c39827feaef281f96232fa 352 Pfam PF00534 Glycosyl transferases group 1 201 306 3.3E-6 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CB4_RS05430 d4f886e1d7c39827feaef281f96232fa 352 Gene3D G3DSA:3.40.50.2000 181 335 5.3E-9 T 29-03-2018 CB4_RS05430 d4f886e1d7c39827feaef281f96232fa 352 SUPERFAMILY SSF53756 12 334 2.83E-31 T 29-03-2018 CB4_RS04855 e1abe30b47ebd4de0b17979e0f24841e 244 PIRSF PIRSF021383 1 228 2.4E-52 T 29-03-2018 IPR014197 Sporulation protein YunB CB4_RS04855 e1abe30b47ebd4de0b17979e0f24841e 244 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 123 211 6.4E-28 T 29-03-2018 IPR014197 Sporulation protein YunB CB4_RS04855 e1abe30b47ebd4de0b17979e0f24841e 244 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 14 215 3.2E-56 T 29-03-2018 IPR014197 Sporulation protein YunB CB4_RS05750 9518c67c8157f54df7fd31b78c7d983f 522 Pfam PF04294 VanW like protein 252 378 8.2E-30 T 29-03-2018 IPR007391 Vancomycin resistance VanW CB4_RS05750 9518c67c8157f54df7fd31b78c7d983f 522 Gene3D G3DSA:2.20.230.10 389 460 1.1E-4 T 29-03-2018 CB4_RS05750 9518c67c8157f54df7fd31b78c7d983f 522 Pfam PF12229 Putative peptidoglycan binding domain 102 207 4.4E-13 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain CB4_RS06115 112b1bbf57eddfa0334e2b95f8c9e276 95 Hamap MF_01448 UPF0473 protein . 11 89 11.921 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 CB4_RS06115 112b1bbf57eddfa0334e2b95f8c9e276 95 Pfam PF06949 Protein of unknown function (DUF1292) 20 88 3.0E-15 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 CB4_RS15230 e0cf14c5d240caa950f1e524ef9c68f2 204 SMART SM01207 8 185 6.3E-81 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CB4_RS15230 e0cf14c5d240caa950f1e524ef9c68f2 204 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 184 5.4E-53 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CB4_RS15230 e0cf14c5d240caa950f1e524ef9c68f2 204 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 5 195 1.5E-58 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CB4_RS15230 e0cf14c5d240caa950f1e524ef9c68f2 204 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 193 21.312 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CB4_RS19745 7e5b5aba70f2f762f0072da79cf8edfe 327 SMART SM00861 5 180 2.0E-64 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CB4_RS19745 7e5b5aba70f2f762f0072da79cf8edfe 327 SUPERFAMILY SSF52518 2 205 7.07E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS19745 7e5b5aba70f2f762f0072da79cf8edfe 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 179 2.6E-48 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CB4_RS19745 7e5b5aba70f2f762f0072da79cf8edfe 327 Pfam PF02780 Transketolase, C-terminal domain 195 317 4.2E-36 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CB4_RS19745 7e5b5aba70f2f762f0072da79cf8edfe 327 SUPERFAMILY SSF52922 190 326 1.05E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS19745 7e5b5aba70f2f762f0072da79cf8edfe 327 Gene3D G3DSA:3.40.50.920 196 326 7.3E-33 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS19745 7e5b5aba70f2f762f0072da79cf8edfe 327 Gene3D G3DSA:3.40.50.970 1 195 3.0E-67 T 29-03-2018 CB4_RS09090 1d2b3cca964cae02a38ee986b2a48330 538 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 1 537 1.1E-84 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CB4_RS09090 1d2b3cca964cae02a38ee986b2a48330 538 PIRSF PIRSF004862 1 538 2.7E-94 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CB4_RS09090 1d2b3cca964cae02a38ee986b2a48330 538 Pfam PF08345 Flagellar M-ring protein C-terminal 261 414 7.6E-18 T 29-03-2018 IPR013556 Flagellar M-ring C-terminal CB4_RS09090 1d2b3cca964cae02a38ee986b2a48330 538 PRINTS PR01009 Flagellar M-ring protein signature 274 292 1.7E-18 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CB4_RS09090 1d2b3cca964cae02a38ee986b2a48330 538 PRINTS PR01009 Flagellar M-ring protein signature 201 219 1.7E-18 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CB4_RS09090 1d2b3cca964cae02a38ee986b2a48330 538 PRINTS PR01009 Flagellar M-ring protein signature 155 169 1.7E-18 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CB4_RS09090 1d2b3cca964cae02a38ee986b2a48330 538 PRINTS PR01009 Flagellar M-ring protein signature 123 141 1.7E-18 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CB4_RS09090 1d2b3cca964cae02a38ee986b2a48330 538 PRINTS PR01009 Flagellar M-ring protein signature 354 378 1.7E-18 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CB4_RS09090 1d2b3cca964cae02a38ee986b2a48330 538 Gene3D G3DSA:1.20.5.100 445 483 5.0E-4 T 29-03-2018 CB4_RS09090 1d2b3cca964cae02a38ee986b2a48330 538 Pfam PF01514 Secretory protein of YscJ/FliF family 31 225 5.2E-53 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF CB4_RS15505 807796d2f4f272228bd782a25c26920e 216 Pfam PF04586 Caudovirus prohead serine protease 18 173 2.1E-46 T 29-03-2018 IPR006433 Prohead protease CB4_RS15505 807796d2f4f272228bd782a25c26920e 216 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 38 171 4.9E-31 T 29-03-2018 IPR006433 Prohead protease CB4_RS15505 807796d2f4f272228bd782a25c26920e 216 Gene3D G3DSA:3.20.16.10 27 214 1.7E-34 T 29-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CB4_RS03030 ba80f1b92c7bfd9712b50190b944333d 103 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 3 103 19.524 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CB4_RS03030 ba80f1b92c7bfd9712b50190b944333d 103 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 98 2.0E-26 T 29-03-2018 CB4_RS16145 f2f022b30591f5d882e9ec60638c4070 358 SUPERFAMILY SSF53850 41 356 3.06E-66 T 29-03-2018 CB4_RS16145 f2f022b30591f5d882e9ec60638c4070 358 Gene3D G3DSA:3.40.190.10 155 311 1.8E-31 T 29-03-2018 CB4_RS16145 f2f022b30591f5d882e9ec60638c4070 358 Gene3D G3DSA:3.40.190.10 26 154 1.1E-18 T 29-03-2018 CB4_RS16145 f2f022b30591f5d882e9ec60638c4070 358 Pfam PF13416 Bacterial extracellular solute-binding protein 61 319 9.6E-41 T 29-03-2018 CB4_RS19720 534059360c82d40265cd04b4f219dcaf 104 SMART SM00450 7 104 1.4E-15 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS19720 534059360c82d40265cd04b4f219dcaf 104 SUPERFAMILY SSF52821 2 97 7.33E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS19720 534059360c82d40265cd04b4f219dcaf 104 Pfam PF00581 Rhodanese-like domain 8 97 1.7E-13 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS19720 534059360c82d40265cd04b4f219dcaf 104 Gene3D G3DSA:3.40.250.10 2 104 4.5E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS16320 96f84f5bc99f705250ff99fe8c8745d2 220 PIRSF PIRSF038973 3 212 5.3E-66 T 29-03-2018 IPR014196 Stage II sporulation protein M CB4_RS16320 96f84f5bc99f705250ff99fe8c8745d2 220 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 9 205 2.9E-63 T 29-03-2018 IPR014196 Stage II sporulation protein M CB4_RS16320 96f84f5bc99f705250ff99fe8c8745d2 220 Pfam PF01944 Stage II sporulation protein M 25 201 1.8E-24 T 29-03-2018 IPR002798 Stage II sporulation protein M-like CB4_RS01465 48918015cd71c66796a804309e65d293 348 SUPERFAMILY SSF54534 173 274 2.49E-21 T 29-03-2018 CB4_RS01465 48918015cd71c66796a804309e65d293 348 Gene3D G3DSA:3.10.50.40 162 295 2.7E-28 T 29-03-2018 CB4_RS01465 48918015cd71c66796a804309e65d293 348 Pfam PF13616 PPIC-type PPIASE domain 171 273 1.3E-25 T 29-03-2018 CB4_RS18570 0f8945948aad668da199fea4b220032e 86 Pfam PF02583 Metal-sensitive transcriptional repressor 5 83 8.8E-24 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CB4_RS13825 c68e7068feb2aabe96b8e2cf9b0514ec 388 Gene3D G3DSA:3.60.21.10 1 71 4.9E-13 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS13825 c68e7068feb2aabe96b8e2cf9b0514ec 388 Gene3D G3DSA:3.60.21.10 72 276 3.8E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS13825 c68e7068feb2aabe96b8e2cf9b0514ec 388 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 276 365 1.0E-5 T 29-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CB4_RS13825 c68e7068feb2aabe96b8e2cf9b0514ec 388 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 252 8.3E-70 T 29-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CB4_RS13825 c68e7068feb2aabe96b8e2cf9b0514ec 388 Pfam PF00149 Calcineurin-like phosphoesterase 1 92 1.4E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CB4_RS13825 c68e7068feb2aabe96b8e2cf9b0514ec 388 SUPERFAMILY SSF56300 1 330 1.82E-51 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 151 163 6.6E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 241 251 6.6E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 111 123 6.6E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 123 137 6.6E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 51 60 6.6E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 173 185 6.6E-20 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 Pfam PF00813 FliP family 55 247 2.5E-82 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 228 240 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 53 72 1.3E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 180 200 1.3E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 201 222 1.3E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 72 92 1.3E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 225 250 1.3E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 92 111 1.3E-64 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CB4_RS09170 7992ed5bd5c1449bacfc2b159986e292 252 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 55 251 4.6E-88 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CB4_RS07355 7cdeecdd30ce11970ceaca9d5317e591 292 Pfam PF03773 Predicted permease 2 283 5.9E-59 T 29-03-2018 IPR005524 Predicted permease DUF318 CB4_RS06355 5aac2b1e591ab25e78a2ef86d2731249 264 Pfam PF02517 CAAX protease self-immunity 114 246 2.2E-7 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CB4_RS18795 23ba11702cd03f82c24a496ee3b64381 132 Pfam PF12844 Helix-turn-helix domain 6 67 2.6E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS18795 23ba11702cd03f82c24a496ee3b64381 132 Gene3D G3DSA:1.10.260.40 4 113 2.3E-15 T 29-03-2018 CB4_RS18795 23ba11702cd03f82c24a496ee3b64381 132 SMART SM00530 8 64 8.1E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS18795 23ba11702cd03f82c24a496ee3b64381 132 SUPERFAMILY SSF47413 2 70 4.79E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS03040 d75beef64f41b35e00c8315f9eb5c735 510 Pfam PF00361 Proton-conducting membrane transporter 136 436 2.0E-66 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03040 d75beef64f41b35e00c8315f9eb5c735 510 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 503 8.6E-142 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03040 d75beef64f41b35e00c8315f9eb5c735 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 172 196 1.1E-31 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03040 d75beef64f41b35e00c8315f9eb5c735 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 396 422 1.1E-31 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03040 d75beef64f41b35e00c8315f9eb5c735 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 142 161 1.1E-31 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03040 d75beef64f41b35e00c8315f9eb5c735 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 344 363 1.1E-31 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03040 d75beef64f41b35e00c8315f9eb5c735 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 256 280 1.1E-31 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS19770 a4151669f1570e810ef74f3858a8bc8c 473 SMART SM00387 354 464 1.4E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS19770 a4151669f1570e810ef74f3858a8bc8c 473 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 259 315 7.4E-13 T 29-03-2018 CB4_RS19770 a4151669f1570e810ef74f3858a8bc8c 473 Gene3D G3DSA:3.30.565.10 309 473 7.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS19770 a4151669f1570e810ef74f3858a8bc8c 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 461 2.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS19770 a4151669f1570e810ef74f3858a8bc8c 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 2.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS19770 a4151669f1570e810ef74f3858a8bc8c 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 2.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CB4_RS19770 a4151669f1570e810ef74f3858a8bc8c 473 SUPERFAMILY SSF55874 315 462 8.73E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS19770 a4151669f1570e810ef74f3858a8bc8c 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 462 3.8E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS19770 a4151669f1570e810ef74f3858a8bc8c 473 Gene3D G3DSA:1.10.287.130 251 308 7.7E-16 T 29-03-2018 CB4_RS07740 85aa5f48b4f2c64d3966e4e237a1a93f 239 Pfam PF14329 Domain of unknown function (DUF4386) 17 232 2.6E-50 T 29-03-2018 IPR025495 Protein of unknown function DUF4386 CB4_RS06170 29e05c96d60e4aa39022be173c82befd 164 Gene3D G3DSA:3.40.630.30 2 150 1.2E-17 T 29-03-2018 CB4_RS06170 29e05c96d60e4aa39022be173c82befd 164 SUPERFAMILY SSF55729 7 144 1.05E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS06170 29e05c96d60e4aa39022be173c82befd 164 Pfam PF00583 Acetyltransferase (GNAT) family 55 137 1.9E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS05835 0e9958d4e526505a02e467453aec2f6f 378 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 12 373 2.3E-105 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 CB4_RS05835 0e9958d4e526505a02e467453aec2f6f 378 Pfam PF01098 Cell cycle protein 11 373 1.4E-85 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CB4_RS08900 f6d74c78a27b5abadebd0b55556ca90c 402 Pfam PF04860 Phage portal protein 41 362 1.0E-79 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CB4_RS08900 f6d74c78a27b5abadebd0b55556ca90c 402 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 35 369 6.2E-75 T 29-03-2018 IPR006427 Phage portal protein, HK97 CB4_RS00070 a58e76c2bd5f738e326026decc8eb055 187 Gene3D G3DSA:3.40.190.10 1 182 4.0E-7 T 29-03-2018 CB4_RS00070 a58e76c2bd5f738e326026decc8eb055 187 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 19 179 3.0E-19 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CB4_RS15995 4d574d0d7a8f5c278cb5d9d23b889b0f 438 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 20 432 37.123 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CB4_RS15995 4d574d0d7a8f5c278cb5d9d23b889b0f 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 322 341 3.9E-29 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CB4_RS15995 4d574d0d7a8f5c278cb5d9d23b889b0f 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 169 190 3.9E-29 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CB4_RS15995 4d574d0d7a8f5c278cb5d9d23b889b0f 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 144 163 3.9E-29 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CB4_RS15995 4d574d0d7a8f5c278cb5d9d23b889b0f 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 116 142 3.9E-29 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CB4_RS15995 4d574d0d7a8f5c278cb5d9d23b889b0f 438 PRINTS PR00447 Natural resistance-associated macrophage protein signature 219 242 3.9E-29 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CB4_RS15995 4d574d0d7a8f5c278cb5d9d23b889b0f 438 Pfam PF01566 Natural resistance-associated macrophage protein 57 407 5.3E-127 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CB4_RS15995 4d574d0d7a8f5c278cb5d9d23b889b0f 438 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 35 400 4.9E-107 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CB4_RS17215 7fa943f0efb9957605219c0bcf324e77 208 Gene3D G3DSA:1.10.357.10 63 204 3.1E-18 T 29-03-2018 CB4_RS17215 7fa943f0efb9957605219c0bcf324e77 208 SUPERFAMILY SSF46689 2 72 9.75E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS17215 7fa943f0efb9957605219c0bcf324e77 208 SUPERFAMILY SSF48498 85 202 2.93E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS17215 7fa943f0efb9957605219c0bcf324e77 208 Gene3D G3DSA:1.10.10.60 1 62 3.6E-18 T 29-03-2018 CB4_RS17215 7fa943f0efb9957605219c0bcf324e77 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 9.5E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS17215 7fa943f0efb9957605219c0bcf324e77 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS17215 7fa943f0efb9957605219c0bcf324e77 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 5.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS07640 4d808496e2152786f30842616ef6248d 150 Gene3D G3DSA:3.30.700.10 10 133 4.9E-8 T 29-03-2018 CB4_RS07640 4d808496e2152786f30842616ef6248d 150 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 29 1.1E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS07640 4d808496e2152786f30842616ef6248d 150 PIRSF PIRSF021292 5 147 7.5E-25 T 29-03-2018 IPR016785 ComG operon protein 4 GO:0030420 CB4_RS07640 4d808496e2152786f30842616ef6248d 150 SUPERFAMILY SSF54523 10 83 2.9E-12 T 29-03-2018 CB4_RS14240 2f8eaa7f633249796500c5fced81b930 428 Gene3D G3DSA:2.140.10.30 11 192 2.4E-16 T 29-03-2018 CB4_RS14240 2f8eaa7f633249796500c5fced81b930 428 Gene3D G3DSA:2.140.10.30 193 394 1.5E-8 T 29-03-2018 CB4_RS14240 2f8eaa7f633249796500c5fced81b930 428 SUPERFAMILY SSF82171 17 393 5.76E-22 T 29-03-2018 CB4_RS17625 a0d33f26a1fcbbbf855d5745d437e28d 333 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 4 333 6.8E-119 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CB4_RS17625 a0d33f26a1fcbbbf855d5745d437e28d 333 Pfam PF13353 4Fe-4S single cluster domain 21 103 5.2E-8 T 29-03-2018 CB4_RS17625 a0d33f26a1fcbbbf855d5745d437e28d 333 SMART SM00729 13 220 2.0E-8 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS17625 a0d33f26a1fcbbbf855d5745d437e28d 333 Gene3D G3DSA:3.20.20.70 1 333 6.7E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS17625 a0d33f26a1fcbbbf855d5745d437e28d 333 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 19 30 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CB4_RS17625 a0d33f26a1fcbbbf855d5745d437e28d 333 SUPERFAMILY SSF102114 4 278 4.71E-75 T 29-03-2018 CB4_RS17625 a0d33f26a1fcbbbf855d5745d437e28d 333 Pfam PF06463 Molybdenum Cofactor Synthesis C 185 309 2.1E-33 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CB4_RS17625 a0d33f26a1fcbbbf855d5745d437e28d 333 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 4 333 39.375 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CB4_RS17625 a0d33f26a1fcbbbf855d5745d437e28d 333 Pfam PF04055 Radical SAM superfamily 17 178 1.5E-32 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS17170 a5e53985d46cb2dee24c83950562e9ba 283 SUPERFAMILY SSF52096 25 275 6.63E-78 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS17170 a5e53985d46cb2dee24c83950562e9ba 283 Pfam PF01039 Carboxyl transferase domain 52 232 4.2E-23 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CB4_RS17170 a5e53985d46cb2dee24c83950562e9ba 283 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 21 274 1.6E-106 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17170 a5e53985d46cb2dee24c83950562e9ba 283 Gene3D G3DSA:3.90.226.10 24 280 4.0E-69 T 29-03-2018 CB4_RS17170 a5e53985d46cb2dee24c83950562e9ba 283 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 5 274 38.037 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17170 a5e53985d46cb2dee24c83950562e9ba 283 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 193 210 6.5E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17170 a5e53985d46cb2dee24c83950562e9ba 283 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 244 253 6.5E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17170 a5e53985d46cb2dee24c83950562e9ba 283 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 122 136 6.5E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17170 a5e53985d46cb2dee24c83950562e9ba 283 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 156 174 6.5E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS17170 a5e53985d46cb2dee24c83950562e9ba 283 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 222 233 6.5E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CB4_RS16420 2de897426806b19f2923481cb610abbc 456 PIRSF PIRSF006603 1 455 1.1E-68 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CB4_RS16420 2de897426806b19f2923481cb610abbc 456 Pfam PF01554 MatE 20 180 3.5E-32 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CB4_RS16420 2de897426806b19f2923481cb610abbc 456 Pfam PF01554 MatE 247 407 1.2E-35 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CB4_RS16420 2de897426806b19f2923481cb610abbc 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 7.0E-99 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CB4_RS00055 8ec440886f5a869e5640f681e6b879df 397 Gene3D G3DSA:1.20.1250.20 198 387 1.1E-25 T 29-03-2018 CB4_RS00055 8ec440886f5a869e5640f681e6b879df 397 SUPERFAMILY SSF103473 1 385 2.35E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS00055 8ec440886f5a869e5640f681e6b879df 397 Gene3D G3DSA:1.20.1250.20 6 197 1.7E-32 T 29-03-2018 CB4_RS00055 8ec440886f5a869e5640f681e6b879df 397 Pfam PF07690 Major Facilitator Superfamily 15 336 8.0E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS00055 8ec440886f5a869e5640f681e6b879df 397 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CB4_RS06530 1757d9cda053ce6e012d31a031302651 367 Gene3D G3DSA:3.40.50.300 56 224 1.1E-33 T 29-03-2018 CB4_RS06530 1757d9cda053ce6e012d31a031302651 367 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 7 367 1.7E-146 T 29-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH CB4_RS06530 1757d9cda053ce6e012d31a031302651 367 SUPERFAMILY SSF52540 64 280 1.54E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS06530 1757d9cda053ce6e012d31a031302651 367 Pfam PF01926 50S ribosome-binding GTPase 163 223 2.0E-13 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS04150 43c0a97a89bb866975b80b2b171d497e 167 Gene3D G3DSA:2.40.50.140 85 167 5.8E-16 T 29-03-2018 CB4_RS04150 43c0a97a89bb866975b80b2b171d497e 167 Pfam PF01957 NfeD-like C-terminal, partner-binding 41 161 2.1E-6 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 PIRSF PIRSF004557 1 435 1.7E-125 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 SUPERFAMILY SSF103491 1 425 9.42E-128 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 430 6.8E-145 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 Gene3D G3DSA:1.10.3370.10 1 435 2.5E-158 T 29-03-2018 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 314 336 2.2E-100 T 29-03-2018 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.2E-100 T 29-03-2018 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 68 88 2.2E-100 T 29-03-2018 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 2.2E-100 T 29-03-2018 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 403 421 2.2E-100 T 29-03-2018 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 2.2E-100 T 29-03-2018 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 369 387 2.2E-100 T 29-03-2018 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 110 133 2.2E-100 T 29-03-2018 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 2.2E-100 T 29-03-2018 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 Pfam PF00344 SecY translocase 69 418 3.9E-115 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 434 30.217 T 29-03-2018 IPR026593 Protein translocase subunit SecY CB4_RS00855 d8195224fd6c86be0057353d16dd8eaf 435 ProSitePatterns PS00755 Protein secY signature 1. 69 88 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CB4_RS08195 b657becdf1111d3b69638342bfcb9e11 517 Gene3D G3DSA:3.90.226.10 256 516 1.5E-67 T 29-03-2018 CB4_RS08195 b657becdf1111d3b69638342bfcb9e11 517 Gene3D G3DSA:3.90.226.10 2 255 1.0E-65 T 29-03-2018 CB4_RS08195 b657becdf1111d3b69638342bfcb9e11 517 SUPERFAMILY SSF52096 10 256 1.42E-66 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS08195 b657becdf1111d3b69638342bfcb9e11 517 SUPERFAMILY SSF52096 218 497 1.52E-82 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS08195 b657becdf1111d3b69638342bfcb9e11 517 Pfam PF01039 Carboxyl transferase domain 33 514 1.1E-159 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CB4_RS18560 212e67884c0a159eb33468537016a41a 147 Pfam PF04463 Protein of unknown function (DUF523) 3 145 8.8E-47 T 29-03-2018 IPR007553 Domain of unknown function DUF523 CB4_RS19565 3460a22f322d4272527089da195c1693 509 Pfam PF15978 Tn7-like transposition protein D 215 321 9.9E-20 T 29-03-2018 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl CB4_RS19565 3460a22f322d4272527089da195c1693 509 Pfam PF15978 Tn7-like transposition protein D 336 442 9.1E-22 T 29-03-2018 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl CB4_RS19565 3460a22f322d4272527089da195c1693 509 Pfam PF06527 TniQ 13 168 6.9E-16 T 29-03-2018 IPR009492 TniQ CB4_RS14830 7651997837e05fac318c594281dd98d9 284 Pfam PF13413 Helix-turn-helix domain 8 67 1.2E-22 T 29-03-2018 CB4_RS14830 7651997837e05fac318c594281dd98d9 284 Gene3D G3DSA:1.10.260.40 1 104 3.4E-9 T 29-03-2018 CB4_RS14830 7651997837e05fac318c594281dd98d9 284 Pfam PF13464 Domain of unknown function (DUF4115) 213 274 6.0E-7 T 29-03-2018 IPR025194 Domain of unknown function DUF4115 CB4_RS02060 db75f9730cb9392b44c34197ab392044 259 Pfam PF09648 YycH protein 46 241 7.1E-32 T 29-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 CB4_RS13820 56a26ebdcde135e610fce273acb8351d 1142 Gene3D G3DSA:3.40.50.300 1 189 7.9E-22 T 29-03-2018 CB4_RS13820 56a26ebdcde135e610fce273acb8351d 1142 Pfam PF13476 AAA domain 6 229 2.5E-13 T 29-03-2018 CB4_RS13820 56a26ebdcde135e610fce273acb8351d 1142 SUPERFAMILY SSF52540 932 979 4.22E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13820 56a26ebdcde135e610fce273acb8351d 1142 SUPERFAMILY SSF52540 1029 1127 4.22E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13820 56a26ebdcde135e610fce273acb8351d 1142 SUPERFAMILY SSF52540 1 180 4.22E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13820 56a26ebdcde135e610fce273acb8351d 1142 Gene3D G3DSA:3.40.50.300 862 1141 7.8E-19 T 29-03-2018 CB4_RS13820 56a26ebdcde135e610fce273acb8351d 1142 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1015 1097 4.7E-15 T 29-03-2018 CB4_RS05365 98750f140d2003e34564bb6fdaff7d07 257 SUPERFAMILY SSF55315 3 97 5.65E-26 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CB4_RS05365 98750f140d2003e34564bb6fdaff7d07 257 SUPERFAMILY SSF75217 90 256 2.49E-42 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CB4_RS05365 98750f140d2003e34564bb6fdaff7d07 257 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 97 1.1E-7 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CB4_RS05365 98750f140d2003e34564bb6fdaff7d07 257 Gene3D G3DSA:3.30.1330.30 1 90 1.1E-23 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CB4_RS05365 98750f140d2003e34564bb6fdaff7d07 257 SMART SM00967 31 99 1.3E-9 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CB4_RS05365 98750f140d2003e34564bb6fdaff7d07 257 Gene3D G3DSA:3.40.1280.10 91 257 1.1E-41 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CB4_RS05365 98750f140d2003e34564bb6fdaff7d07 257 Pfam PF00588 SpoU rRNA Methylase family 110 249 1.2E-33 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CB4_RS05300 77e0d8c092dd399c42141ec0e53dc67f 447 TIGRFAM TIGR03173 pbuX: xanthine permease 13 423 3.1E-159 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CB4_RS05300 77e0d8c092dd399c42141ec0e53dc67f 447 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 8 421 3.8E-129 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CB4_RS05300 77e0d8c092dd399c42141ec0e53dc67f 447 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 338 358 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CB4_RS05300 77e0d8c092dd399c42141ec0e53dc67f 447 Pfam PF00860 Permease family 12 390 2.8E-110 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CB4_RS14715 5963c4b92903847d4e5aa5d743c84d21 83 Pfam PF10628 Outer spore coat protein E (CotE) 9 79 3.7E-33 T 29-03-2018 IPR018901 Spore coat protein CotE CB4_RS00740 6a2884973490cab98cd6da7633c8a354 253 SUPERFAMILY SSF88713 16 242 4.45E-60 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS00740 6a2884973490cab98cd6da7633c8a354 253 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 51 242 7.7E-81 T 29-03-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB CB4_RS00740 6a2884973490cab98cd6da7633c8a354 253 Pfam PF01522 Polysaccharide deacetylase 52 174 2.1E-29 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS00740 6a2884973490cab98cd6da7633c8a354 253 Gene3D G3DSA:3.20.20.370 30 252 6.6E-55 T 29-03-2018 CB4_RS16480 0fb7beec849ea24da7e129b8ffe01507 269 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 258 32.02 T 29-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CB4_RS16480 0fb7beec849ea24da7e129b8ffe01507 269 SUPERFAMILY SSF64167 3 253 2.09E-71 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CB4_RS16480 0fb7beec849ea24da7e129b8ffe01507 269 Pfam PF01975 Survival protein SurE 4 190 9.7E-57 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CB4_RS16480 0fb7beec849ea24da7e129b8ffe01507 269 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 241 1.8E-56 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CB4_RS16480 0fb7beec849ea24da7e129b8ffe01507 269 Gene3D G3DSA:3.40.1210.10 2 266 1.7E-79 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CB4_RS16965 57e1bce50567348ce2e0cde8f9fd5938 224 Pfam PF03741 Integral membrane protein TerC family 11 181 4.5E-45 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CB4_RS16965 57e1bce50567348ce2e0cde8f9fd5938 224 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 182 4.0E-69 T 29-03-2018 IPR022301 Integral membrane protein YjbE CB4_RS04970 d815374bbed47b2fc74521d12ab4f4e9 291 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 14 256 6.5E-7 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CB4_RS09435 1cf008a794b74050cf1aec1604686a1e 199 SUPERFAMILY SSF52507 6 192 1.57E-31 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CB4_RS09435 1cf008a794b74050cf1aec1604686a1e 199 Pfam PF02441 Flavoprotein 6 165 2.0E-15 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CB4_RS09435 1cf008a794b74050cf1aec1604686a1e 199 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 1.3E-88 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B CB4_RS09435 1cf008a794b74050cf1aec1604686a1e 199 PIRSF PIRSF001390 1 195 1.7E-79 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B CB4_RS09435 1cf008a794b74050cf1aec1604686a1e 199 Gene3D G3DSA:3.40.50.1950 6 198 1.6E-26 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CB4_RS04075 57c6183d2e601dc018f0cb1210d2f7e9 203 Pfam PF02630 SCO1/SenC 44 172 1.0E-15 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS04075 57c6183d2e601dc018f0cb1210d2f7e9 203 Gene3D G3DSA:3.40.30.10 32 200 7.2E-29 T 29-03-2018 CB4_RS04075 57c6183d2e601dc018f0cb1210d2f7e9 203 SUPERFAMILY SSF52833 41 201 7.34E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS06560 1c5c2a55e949fb7610d7586ec2624bfd 263 Pfam PF13649 Methyltransferase domain 50 147 8.5E-19 T 29-03-2018 CB4_RS06560 1c5c2a55e949fb7610d7586ec2624bfd 263 Gene3D G3DSA:3.40.50.150 4 150 7.3E-25 T 29-03-2018 CB4_RS06560 1c5c2a55e949fb7610d7586ec2624bfd 263 SUPERFAMILY SSF53335 13 259 3.92E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS06560 1c5c2a55e949fb7610d7586ec2624bfd 263 Gene3D G3DSA:2.20.25.110 155 217 8.1E-24 T 29-03-2018 CB4_RS12320 3f7a108887f4c8ba2ac03bdec0ba89eb 305 Pfam PF11185 Protein of unknown function (DUF2971) 82 201 5.4E-12 T 29-03-2018 IPR021352 Protein of unknown function DUF2971 CB4_RS15700 f06a1ea2f92b3eb4f27ed63b37f00edf 130 SUPERFAMILY SSF55729 6 121 2.16E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS15700 f06a1ea2f92b3eb4f27ed63b37f00edf 130 Gene3D G3DSA:3.40.630.30 3 125 7.3E-25 T 29-03-2018 CB4_RS15700 f06a1ea2f92b3eb4f27ed63b37f00edf 130 Pfam PF13302 Acetyltransferase (GNAT) domain 7 96 7.1E-23 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS18475 70584684211a9b0e057b1918bdc1021f 234 Gene3D G3DSA:2.60.120.10 12 131 3.0E-49 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS18475 70584684211a9b0e057b1918bdc1021f 234 SUPERFAMILY SSF51182 1 233 1.01E-69 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS18475 70584684211a9b0e057b1918bdc1021f 234 Pfam PF02678 Pirin 12 118 7.9E-35 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CB4_RS18475 70584684211a9b0e057b1918bdc1021f 234 PIRSF PIRSF006232 1 232 7.0E-52 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CB4_RS18475 70584684211a9b0e057b1918bdc1021f 234 Gene3D G3DSA:2.60.120.10 132 234 1.0E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS07995 09da0fd6d708662e9687c0391f66b407 285 Gene3D G3DSA:2.60.200.30 137 259 4.2E-38 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CB4_RS07995 09da0fd6d708662e9687c0391f66b407 285 Pfam PF01513 ATP-NAD kinase 4 266 2.1E-60 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CB4_RS07995 09da0fd6d708662e9687c0391f66b407 285 Hamap MF_00361 NAD kinase [nadK]. 2 282 32.232 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CB4_RS07995 09da0fd6d708662e9687c0391f66b407 285 SUPERFAMILY SSF111331 3 280 1.57E-84 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CB4_RS07995 09da0fd6d708662e9687c0391f66b407 285 Gene3D G3DSA:3.40.50.10330 1 136 4.5E-33 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CB4_RS04185 c2b46dcb84057af6afbd1c7861f9fd43 166 Pfam PF07301 Protein of unknown function (DUF1453) 6 148 8.0E-56 T 29-03-2018 IPR009916 Protein of unknown function DUF1453 CB4_RS04185 c2b46dcb84057af6afbd1c7861f9fd43 166 PIRSF PIRSF021441 1 161 9.1E-59 T 29-03-2018 IPR031306 CcdC protein CB4_RS08640 c4ea274d5fcb4cda2cac2453275002ae 352 SUPERFAMILY SSF102114 6 271 8.93E-53 T 29-03-2018 CB4_RS08640 c4ea274d5fcb4cda2cac2453275002ae 352 Pfam PF16199 Radical_SAM C-terminal domain 187 272 3.4E-20 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CB4_RS08640 c4ea274d5fcb4cda2cac2453275002ae 352 Pfam PF04055 Radical SAM superfamily 11 172 2.9E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS08640 c4ea274d5fcb4cda2cac2453275002ae 352 Gene3D G3DSA:3.20.20.70 2 319 8.3E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS08640 c4ea274d5fcb4cda2cac2453275002ae 352 SMART SM00729 6 226 1.0E-30 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS15525 af46a82a4535f3b9bbeb1da4a1f5a898 131 Gene3D G3DSA:3.40.1800.10 36 113 3.2E-11 T 29-03-2018 CB4_RS15525 af46a82a4535f3b9bbeb1da4a1f5a898 131 SMART SM00507 47 102 1.9E-5 T 29-03-2018 IPR003615 HNH nuclease CB4_RS15525 af46a82a4535f3b9bbeb1da4a1f5a898 131 Pfam PF01844 HNH endonuclease 59 106 1.9E-6 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CB4_RS13150 5b6943ca1c166493b4878f4a2da1470a 378 Pfam PF00395 S-layer homology domain 61 102 3.3E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS13150 5b6943ca1c166493b4878f4a2da1470a 378 Pfam PF00395 S-layer homology domain 194 237 6.5E-5 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS12070 977bff50c896a6dbce9a8972020b24de 303 Gene3D G3DSA:3.10.180.10 1 140 2.1E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS12070 977bff50c896a6dbce9a8972020b24de 303 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 240 261 - T 29-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CB4_RS12070 977bff50c896a6dbce9a8972020b24de 303 SUPERFAMILY SSF54593 1 270 3.42E-44 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS12070 977bff50c896a6dbce9a8972020b24de 303 Gene3D G3DSA:3.10.180.10 146 301 8.2E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS12070 977bff50c896a6dbce9a8972020b24de 303 TIGRFAM TIGR03211 catechol_2_3: catechol 2,3 dioxygenase 3 301 5.8E-128 T 29-03-2018 IPR017624 Catechol 2,3 dioxygenase GO:0008198|GO:0018577|GO:0019439|GO:0055114 KEGG: 00361+1.13.11.2|KEGG: 00362+1.13.11.2|KEGG: 00622+1.13.11.2|KEGG: 00643+1.13.11.2|MetaCyc: PWY-5419|MetaCyc: PWY-5641 CB4_RS12070 977bff50c896a6dbce9a8972020b24de 303 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 146 262 2.1E-15 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CB4_RS10905 2637c54b0be74c5d203acc48279381cc 81 Pfam PF01206 Sulfurtransferase TusA 11 80 2.5E-16 T 29-03-2018 IPR001455 TusA-like domain CB4_RS10905 2637c54b0be74c5d203acc48279381cc 81 SUPERFAMILY SSF64307 6 80 4.19E-18 T 29-03-2018 IPR001455 TusA-like domain CB4_RS10905 2637c54b0be74c5d203acc48279381cc 81 Gene3D G3DSA:3.30.110.40 2 81 9.5E-17 T 29-03-2018 IPR001455 TusA-like domain CB4_RS10905 2637c54b0be74c5d203acc48279381cc 81 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 12 36 - T 29-03-2018 IPR001455 TusA-like domain CB4_RS15190 805362e3d57a94359ea28cb20a753ce9 76 SUPERFAMILY SSF51219 7 72 1.18E-34 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CB4_RS15190 805362e3d57a94359ea28cb20a753ce9 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 42 58 3.3E-33 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CB4_RS15190 805362e3d57a94359ea28cb20a753ce9 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 9 26 3.3E-33 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CB4_RS15190 805362e3d57a94359ea28cb20a753ce9 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 26 42 3.3E-33 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CB4_RS15190 805362e3d57a94359ea28cb20a753ce9 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 58 74 3.3E-33 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CB4_RS15190 805362e3d57a94359ea28cb20a753ce9 76 Gene3D G3DSA:2.60.40.50 8 73 2.3E-38 T 29-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain CB4_RS15190 805362e3d57a94359ea28cb20a753ce9 76 Hamap MF_00798 Transcription attenuation protein MtrB [mtrB]. 1 73 28.507 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 CB4_RS15190 805362e3d57a94359ea28cb20a753ce9 76 Pfam PF02081 Tryptophan RNA-binding attenuator protein 6 72 1.7E-39 T 29-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain CB4_RS06490 efe90ed52d0993d06a5cb3473e24763a 346 SUPERFAMILY SSF52518 2 341 2.76E-101 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS06490 efe90ed52d0993d06a5cb3473e24763a 346 Gene3D G3DSA:3.40.50.970 1 340 4.2E-89 T 29-03-2018 CB4_RS06490 efe90ed52d0993d06a5cb3473e24763a 346 Pfam PF00676 Dehydrogenase E1 component 29 318 1.8E-99 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CB4_RS06490 efe90ed52d0993d06a5cb3473e24763a 346 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 1 339 5.8E-143 T 29-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CB4_RS07300 c1a59ffbe08cb4cdf70e077ae29d8f11 122 Gene3D G3DSA:3.40.30.10 8 107 6.9E-21 T 29-03-2018 CB4_RS07300 c1a59ffbe08cb4cdf70e077ae29d8f11 122 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 10 85 3.4E-8 T 29-03-2018 CB4_RS07300 c1a59ffbe08cb4cdf70e077ae29d8f11 122 SUPERFAMILY SSF52833 10 90 3.13E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS00575 6796d62b66667d98eac15351a2bc79d8 307 SUPERFAMILY SSF53474 222 300 1.0E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS00575 6796d62b66667d98eac15351a2bc79d8 307 SUPERFAMILY SSF53474 5 148 1.0E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS00575 6796d62b66667d98eac15351a2bc79d8 307 Gene3D G3DSA:3.40.50.1820 1 305 4.0E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS00575 6796d62b66667d98eac15351a2bc79d8 307 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 15 149 4.6E-17 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CB4_RS00450 8df0906d1c99f5be7282520841f44133 173 Pfam PF04203 Sortase family 33 170 1.1E-19 T 29-03-2018 IPR005754 Sortase family CB4_RS00450 8df0906d1c99f5be7282520841f44133 173 Gene3D G3DSA:2.40.260.10 19 173 5.5E-21 T 29-03-2018 IPR023365 Sortase domain CB4_RS00450 8df0906d1c99f5be7282520841f44133 173 SUPERFAMILY SSF63817 30 171 3.14E-16 T 29-03-2018 IPR023365 Sortase domain CB4_RS15080 14e00164e824922dfc4a4ca81fe6fa8d 85 Pfam PF09388 Spo0E like sporulation regulatory protein 17 60 2.4E-6 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CB4_RS15080 14e00164e824922dfc4a4ca81fe6fa8d 85 SUPERFAMILY SSF140500 12 62 4.32E-7 T 29-03-2018 CB4_RS08090 2ade7af2a2e4ab03eca9b269a83dbd12 212 Hamap MF_01851 UPF0637 protein . 3 203 37.118 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 CB4_RS08090 2ade7af2a2e4ab03eca9b269a83dbd12 212 SUPERFAMILY SSF142913 2 206 1.12E-77 T 29-03-2018 CB4_RS08090 2ade7af2a2e4ab03eca9b269a83dbd12 212 PIRSF PIRSF021332 1 207 7.0E-79 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 CB4_RS08090 2ade7af2a2e4ab03eca9b269a83dbd12 212 Pfam PF06335 Protein of unknown function (DUF1054) 4 201 2.3E-78 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 Pfam PF00395 S-layer homology domain 49 93 2.4E-6 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 Pfam PF00395 S-layer homology domain 173 216 1.2E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 Pfam PF00395 S-layer homology domain 111 154 3.9E-12 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 SMART SM00736 543 637 0.019 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 SMART SM00736 638 732 0.13 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 SMART SM00736 828 922 0.13 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 SMART SM00736 733 827 0.077 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 Gene3D G3DSA:2.60.40.1080 732 822 6.7E-10 T 29-03-2018 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 Gene3D G3DSA:2.60.40.1080 638 727 6.1E-10 T 29-03-2018 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 Gene3D G3DSA:2.60.40.1080 828 916 6.1E-10 T 29-03-2018 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 Gene3D G3DSA:2.60.40.10 917 1013 2.7E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 SUPERFAMILY SSF49373 647 718 7.85E-5 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 Gene3D G3DSA:2.60.40.10 535 631 1.1E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 SMART SM00635 633 717 0.03 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 SMART SM00635 542 622 21.0 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 SMART SM00635 728 812 0.036 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 SMART SM00635 827 907 0.13 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS18815 b449139efd56550325d4cea388777ec9 1266 SUPERFAMILY SSF49373 837 908 7.85E-5 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CB4_RS06815 eaecf6f81ed60315af7c029ac78512ae 377 Gene3D G3DSA:2.160.20.80 186 376 5.6E-34 T 29-03-2018 CB4_RS06815 eaecf6f81ed60315af7c029ac78512ae 377 Pfam PF13599 Pentapeptide repeats (9 copies) 220 288 8.7E-7 T 29-03-2018 IPR001646 Pentapeptide repeat CB4_RS06815 eaecf6f81ed60315af7c029ac78512ae 377 Pfam PF00805 Pentapeptide repeats (8 copies) 313 347 3.2E-10 T 29-03-2018 IPR001646 Pentapeptide repeat CB4_RS06815 eaecf6f81ed60315af7c029ac78512ae 377 SUPERFAMILY SSF141571 220 374 2.26E-33 T 29-03-2018 CB4_RS02565 c4ac0598896d90a52466d7f5a20a359d 201 SMART SM01118 1 199 8.1E-8 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CB4_RS02565 c4ac0598896d90a52466d7f5a20a359d 201 Gene3D G3DSA:2.40.320.10 1 200 4.8E-29 T 29-03-2018 CB4_RS02565 c4ac0598896d90a52466d7f5a20a359d 201 Pfam PF01928 CYTH domain 1 174 9.3E-12 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CB4_RS02565 c4ac0598896d90a52466d7f5a20a359d 201 SUPERFAMILY SSF55154 1 195 2.29E-20 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CB4_RS08700 245db8abaf87c11b577e18aaadde02e8 299 Gene3D G3DSA:1.10.1580.10 180 272 1.4E-22 T 29-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain CB4_RS08700 245db8abaf87c11b577e18aaadde02e8 299 PIRSF PIRSF006230 1 283 1.1E-101 T 29-03-2018 IPR016478 GTPase, MTG1 CB4_RS08700 245db8abaf87c11b577e18aaadde02e8 299 Pfam PF01926 50S ribosome-binding GTPase 123 210 1.8E-14 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CB4_RS08700 245db8abaf87c11b577e18aaadde02e8 299 SUPERFAMILY SSF52540 9 212 6.48E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS08700 245db8abaf87c11b577e18aaadde02e8 299 Gene3D G3DSA:3.40.50.300 12 179 5.2E-33 T 29-03-2018 CB4_RS08700 245db8abaf87c11b577e18aaadde02e8 299 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 2.1E-114 T 29-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis CB4_RS03165 106570abdd50ffc18e360a491ae45bb9 208 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 5 194 38.226 T 29-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 CB4_RS03165 106570abdd50ffc18e360a491ae45bb9 208 SUPERFAMILY SSF53697 9 195 2.45E-53 T 29-03-2018 CB4_RS03165 106570abdd50ffc18e360a491ae45bb9 208 Gene3D G3DSA:3.40.50.10490 5 204 3.4E-40 T 29-03-2018 CB4_RS03165 106570abdd50ffc18e360a491ae45bb9 208 Pfam PF13580 SIS domain 28 151 1.3E-25 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CB4_RS11980 4af0b38deae261014c88e7a5665305f5 579 Pfam PF16147 Domain of unknown function (DUF4855) 303 560 8.5E-45 T 29-03-2018 IPR032329 Protein of unknown function DUF4855 CB4_RS11980 4af0b38deae261014c88e7a5665305f5 579 Gene3D G3DSA:2.40.50.110 111 194 0.014 T 29-03-2018 CB4_RS16010 8af8c0b9e155eb125a4990dfc2bf2fcf 193 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 168 1.2E-60 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CB4_RS16010 8af8c0b9e155eb125a4990dfc2bf2fcf 193 Gene3D G3DSA:1.10.10.10 1 85 3.7E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16010 8af8c0b9e155eb125a4990dfc2bf2fcf 193 Gene3D G3DSA:1.10.10.10 86 177 3.4E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16010 8af8c0b9e155eb125a4990dfc2bf2fcf 193 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 178 1.2E-57 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CB4_RS16010 8af8c0b9e155eb125a4990dfc2bf2fcf 193 PIRSF PIRSF019345 2 192 8.4E-58 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CB4_RS16010 8af8c0b9e155eb125a4990dfc2bf2fcf 193 SUPERFAMILY SSF46785 3 82 5.98E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16010 8af8c0b9e155eb125a4990dfc2bf2fcf 193 SUPERFAMILY SSF46785 87 160 1.36E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16010 8af8c0b9e155eb125a4990dfc2bf2fcf 193 Hamap MF_01804 Segregation and condensation protein B [scpB]. 4 186 34.621 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CB4_RS13715 f945f86951e68388f936291100205e25 263 Gene3D G3DSA:1.10.3720.10 7 261 3.8E-35 T 29-03-2018 CB4_RS13715 f945f86951e68388f936291100205e25 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 258 8.9E-7 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS13715 f945f86951e68388f936291100205e25 263 SUPERFAMILY SSF161098 3 259 4.02E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS00250 4b4630b03cb313c0ad44d202e586ea1f 144 Gene3D G3DSA:1.20.1260.10 2 77 7.4E-17 T 29-03-2018 IPR012347 Ferritin-related CB4_RS00250 4b4630b03cb313c0ad44d202e586ea1f 144 Gene3D G3DSA:1.20.1260.10 78 144 8.6E-14 T 29-03-2018 IPR012347 Ferritin-related CB4_RS00250 4b4630b03cb313c0ad44d202e586ea1f 144 Pfam PF02915 Rubrerythrin 13 137 8.7E-27 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CB4_RS00250 4b4630b03cb313c0ad44d202e586ea1f 144 SUPERFAMILY SSF47240 7 142 3.07E-39 T 29-03-2018 IPR009078 Ferritin-like superfamily CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 Gene3D G3DSA:3.30.1490.20 141 201 1.7E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 Pfam PF07478 D-ala D-ala ligase C-terminus 134 336 3.3E-74 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 93 104 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 Pfam PF01820 D-ala D-ala ligase N-terminus 6 116 2.5E-31 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 336 8.2E-110 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 5 340 42.019 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 SUPERFAMILY SSF56059 126 344 3.36E-59 T 29-03-2018 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 Gene3D G3DSA:3.40.50.20 1 136 6.9E-46 T 29-03-2018 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 281 310 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 PIRSF PIRSF039102 2 348 4.9E-113 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 Gene3D G3DSA:3.30.470.20 202 349 1.4E-42 T 29-03-2018 CB4_RS07035 14586f3372bd7685eb842c50e9138784 358 SUPERFAMILY SSF52440 4 125 3.84E-36 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CB4_RS01455 63d523abf957d2c7ed245b6cd9bfdb95 544 Pfam PF01943 Polysaccharide biosynthesis protein 9 316 9.2E-36 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CB4_RS01455 63d523abf957d2c7ed245b6cd9bfdb95 544 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 367 516 3.0E-26 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CB4_RS01455 63d523abf957d2c7ed245b6cd9bfdb95 544 PIRSF PIRSF038958 4 533 2.9E-111 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CB4_RS03045 f99892ca7b8a7069cde01deeb9808c70 512 Pfam PF00361 Proton-conducting membrane transporter 133 443 9.0E-66 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03045 f99892ca7b8a7069cde01deeb9808c70 512 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 14 493 1.6E-113 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CB4_RS03045 f99892ca7b8a7069cde01deeb9808c70 512 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 11 493 17.543 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CB4_RS10270 b72ce4bcc5e02133c8e9dd78f49aeb2b 212 Gene3D G3DSA:3.40.630.30 28 197 3.7E-5 T 29-03-2018 CB4_RS06285 2d0307e06088768fd1b98dad9c2ab11c 246 Gene3D G3DSA:1.10.3290.10 3 246 1.5E-69 T 29-03-2018 IPR003812 Fido domain CB4_RS06285 2d0307e06088768fd1b98dad9c2ab11c 246 Pfam PF02661 Fic/DOC family 94 191 1.1E-25 T 29-03-2018 IPR003812 Fido domain CB4_RS06285 2d0307e06088768fd1b98dad9c2ab11c 246 SUPERFAMILY SSF140931 71 245 1.24E-45 T 29-03-2018 IPR003812 Fido domain CB4_RS12210 1b415d033e1f5b1d5dfbd626956341ef 187 Gene3D G3DSA:3.30.200.20 8 84 1.0E-5 T 29-03-2018 CB4_RS12210 1b415d033e1f5b1d5dfbd626956341ef 187 Gene3D G3DSA:1.10.510.10 85 161 5.8E-8 T 29-03-2018 CB4_RS12210 1b415d033e1f5b1d5dfbd626956341ef 187 Pfam PF00069 Protein kinase domain 23 143 2.9E-7 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CB4_RS12210 1b415d033e1f5b1d5dfbd626956341ef 187 SUPERFAMILY SSF56112 23 148 2.19E-15 T 29-03-2018 IPR011009 Protein kinase-like domain CB4_RS00545 40b00d222616b0baa341c07126308db4 253 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 232 2.3E-29 T 29-03-2018 IPR023214 HAD-like domain CB4_RS00545 40b00d222616b0baa341c07126308db4 253 Gene3D G3DSA:3.40.50.1000 2 239 5.5E-19 T 29-03-2018 IPR023214 HAD-like domain CB4_RS00545 40b00d222616b0baa341c07126308db4 253 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 216 7.6E-16 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CB4_RS00545 40b00d222616b0baa341c07126308db4 253 SUPERFAMILY SSF56784 3 233 1.53E-34 T 29-03-2018 IPR023214 HAD-like domain CB4_RS13315 cc471cd2fed28582a9350c0119012684 58 Gene3D G3DSA:3.30.420.10 1 58 2.6E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS13315 cc471cd2fed28582a9350c0119012684 58 SUPERFAMILY SSF53098 1 52 5.31E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS13315 cc471cd2fed28582a9350c0119012684 58 Pfam PF13333 Integrase core domain 2 56 1.9E-14 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CB4_RS09475 4187919d9447e6e7617ae7bb6ab0979e 189 Pfam PF01872 RibD C-terminal domain 9 180 3.0E-24 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CB4_RS09475 4187919d9447e6e7617ae7bb6ab0979e 189 Gene3D G3DSA:3.40.430.10 8 184 3.1E-40 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CB4_RS09475 4187919d9447e6e7617ae7bb6ab0979e 189 SUPERFAMILY SSF53597 8 185 6.41E-35 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CB4_RS19845 206d2c4690cee0daeaf0f78b761e8996 69 SUPERFAMILY SSF47413 10 51 1.42E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS19845 206d2c4690cee0daeaf0f78b761e8996 69 Gene3D G3DSA:1.10.260.40 5 65 5.0E-5 T 29-03-2018 CB4_RS07105 4f3fa0201aa6e595c093c5eff88a017a 132 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 66 77 - T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CB4_RS07105 4f3fa0201aa6e595c093c5eff88a017a 132 Pfam PF01219 Prokaryotic diacylglycerol kinase 12 114 3.0E-33 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CB4_RS07105 4f3fa0201aa6e595c093c5eff88a017a 132 Gene3D G3DSA:1.10.3830.10 3 116 2.4E-38 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CB4_RS12090 5a6ea92665cd28ecade641c94a94915e 344 SUPERFAMILY SSF51569 6 272 5.68E-66 T 29-03-2018 CB4_RS12090 5a6ea92665cd28ecade641c94a94915e 344 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 344 179.124 T 29-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CB4_RS12090 5a6ea92665cd28ecade641c94a94915e 344 Pfam PF07836 DmpG-like communication domain 275 336 4.9E-32 T 29-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CB4_RS12090 5a6ea92665cd28ecade641c94a94915e 344 SUPERFAMILY SSF89000 289 338 6.67E-19 T 29-03-2018 CB4_RS12090 5a6ea92665cd28ecade641c94a94915e 344 Gene3D G3DSA:3.20.20.70 1 266 5.3E-59 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS12090 5a6ea92665cd28ecade641c94a94915e 344 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 273 335 1.0E-23 T 29-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CB4_RS12090 5a6ea92665cd28ecade641c94a94915e 344 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 8 338 1.3E-162 T 29-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CB4_RS12090 5a6ea92665cd28ecade641c94a94915e 344 Pfam PF00682 HMGL-like 9 265 1.2E-57 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CB4_RS12090 5a6ea92665cd28ecade641c94a94915e 344 Gene3D G3DSA:1.10.8.60 278 338 1.3E-31 T 29-03-2018 CB4_RS06165 fd72ffbba6a95c306a5f7055853d96d4 370 PIRSF PIRSF026508 2 367 1.2E-109 T 29-03-2018 IPR008863 Toxic anion resistance CB4_RS06165 fd72ffbba6a95c306a5f7055853d96d4 370 Pfam PF05816 Toxic anion resistance protein (TelA) 31 361 1.8E-118 T 29-03-2018 IPR008863 Toxic anion resistance CB4_RS15110 989a2ebf50dbc61716a59616709935ab 205 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 9 194 2.0E-36 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CB4_RS15110 989a2ebf50dbc61716a59616709935ab 205 SUPERFAMILY SSF51366 2 196 9.26E-39 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CB4_RS15110 989a2ebf50dbc61716a59616709935ab 205 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 199 28.353 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CB4_RS15110 989a2ebf50dbc61716a59616709935ab 205 Gene3D G3DSA:3.20.20.70 1 201 8.2E-53 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS02890 28e76daa2076b0ee06c423ebbd7d0400 227 Gene3D G3DSA:3.40.50.2300 153 227 2.8E-4 T 29-03-2018 CB4_RS02890 28e76daa2076b0ee06c423ebbd7d0400 227 Gene3D G3DSA:3.40.50.2300 1 152 2.8E-37 T 29-03-2018 CB4_RS02890 28e76daa2076b0ee06c423ebbd7d0400 227 SUPERFAMILY SSF52788 1 137 3.79E-31 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CB4_RS02890 28e76daa2076b0ee06c423ebbd7d0400 227 SMART SM00226 1 139 6.1E-24 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CB4_RS02890 28e76daa2076b0ee06c423ebbd7d0400 227 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 7.8E-8 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CB4_RS02890 28e76daa2076b0ee06c423ebbd7d0400 227 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 76 91 7.8E-8 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CB4_RS02890 28e76daa2076b0ee06c423ebbd7d0400 227 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 98 111 7.8E-8 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CB4_RS02890 28e76daa2076b0ee06c423ebbd7d0400 227 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 137 1.1E-28 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CB4_RS01005 dd928958ceb1f808dcf3eecdada74c16 279 Pfam PF01145 SPFH domain / Band 7 family 53 227 1.3E-22 T 29-03-2018 IPR001107 Band 7 domain CB4_RS01005 dd928958ceb1f808dcf3eecdada74c16 279 SUPERFAMILY SSF117892 87 215 5.62E-13 T 29-03-2018 IPR001107 Band 7 domain CB4_RS01005 dd928958ceb1f808dcf3eecdada74c16 279 SMART SM00244 49 213 2.1E-14 T 29-03-2018 IPR001107 Band 7 domain CB4_RS17630 b905ef2a9695a38ba74befe807fe4de5 339 Pfam PF00899 ThiF family 5 241 2.0E-58 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CB4_RS17630 b905ef2a9695a38ba74befe807fe4de5 339 Gene3D G3DSA:3.40.50.720 21 270 3.3E-60 T 29-03-2018 CB4_RS17630 b905ef2a9695a38ba74befe807fe4de5 339 SUPERFAMILY SSF69572 3 328 1.57E-79 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CB4_RS03145 4287dede17b28b2fc9ea3c43b85ce656 424 Gene3D G3DSA:3.40.50.300 4 273 1.3E-52 T 29-03-2018 CB4_RS03145 4287dede17b28b2fc9ea3c43b85ce656 424 Gene3D G3DSA:2.70.50.60 274 413 5.9E-24 T 29-03-2018 CB4_RS03145 4287dede17b28b2fc9ea3c43b85ce656 424 SUPERFAMILY SSF52540 35 253 1.01E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03145 4287dede17b28b2fc9ea3c43b85ce656 424 Pfam PF00005 ABC transporter 45 177 5.2E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS03145 4287dede17b28b2fc9ea3c43b85ce656 424 Pfam PF14524 Wzt C-terminal domain 280 413 1.0E-22 T 29-03-2018 IPR029439 Wzt, C-terminal CB4_RS03145 4287dede17b28b2fc9ea3c43b85ce656 424 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS03145 4287dede17b28b2fc9ea3c43b85ce656 424 SMART SM00382 54 224 1.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS19145 9cbbe04de926ee5718a3002496200f0b 98 Pfam PF17247 Family of unknown function (DUF5316) 23 93 1.3E-21 T 29-03-2018 IPR035167 Protein of unknown function DUF5316 CB4_RS18220 e33cacdd565a783ef1218e0a6dae1311 140 SMART SM00881 15 107 7.0E-19 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CB4_RS18220 e33cacdd565a783ef1218e0a6dae1311 140 Gene3D G3DSA:3.40.50.720 15 135 1.2E-33 T 29-03-2018 CB4_RS18220 e33cacdd565a783ef1218e0a6dae1311 140 SUPERFAMILY SSF51735 2 134 2.17E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS18220 e33cacdd565a783ef1218e0a6dae1311 140 Pfam PF13380 CoA binding domain 19 133 5.4E-40 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CB4_RS02715 53ebfecbf492d9c3dfea212deb0ddd5d 674 Gene3D G3DSA:3.40.710.10 257 651 4.8E-118 T 29-03-2018 CB4_RS02715 53ebfecbf492d9c3dfea212deb0ddd5d 674 SUPERFAMILY SSF53955 51 259 7.31E-72 T 29-03-2018 IPR023346 Lysozyme-like domain CB4_RS02715 53ebfecbf492d9c3dfea212deb0ddd5d 674 Pfam PF00905 Penicillin binding protein transpeptidase domain 328 593 1.2E-32 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CB4_RS02715 53ebfecbf492d9c3dfea212deb0ddd5d 674 Gene3D G3DSA:1.10.3810.10 54 254 1.7E-73 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CB4_RS02715 53ebfecbf492d9c3dfea212deb0ddd5d 674 Pfam PF00912 Transglycosylase 64 237 1.7E-60 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CB4_RS02715 53ebfecbf492d9c3dfea212deb0ddd5d 674 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 73 601 8.8E-184 T 29-03-2018 CB4_RS02715 53ebfecbf492d9c3dfea212deb0ddd5d 674 SUPERFAMILY SSF56601 219 241 1.03E-125 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS02715 53ebfecbf492d9c3dfea212deb0ddd5d 674 SUPERFAMILY SSF56601 271 653 1.03E-125 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS11800 a24fbe8603498a690fb16fdab9719437 72 SUPERFAMILY SSF47413 11 70 7.11E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS11800 a24fbe8603498a690fb16fdab9719437 72 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 71 3.5E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS11800 a24fbe8603498a690fb16fdab9719437 72 Gene3D G3DSA:1.10.260.40 1 72 4.5E-7 T 29-03-2018 CB4_RS04330 e19a93c34aa4cd0e0457f84ec5461429 90 Gene3D G3DSA:3.30.70.1060 2 84 1.0E-19 T 29-03-2018 CB4_RS04330 e19a93c34aa4cd0e0457f84ec5461429 90 SUPERFAMILY SSF54909 1 82 5.09E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CB4_RS04330 e19a93c34aa4cd0e0457f84ec5461429 90 Pfam PF03795 YCII-related domain 1 81 2.0E-11 T 29-03-2018 IPR005545 YCII-related CB4_RS10400 e950e50801c3cee2091783ef18714073 490 PIRSF PIRSF006060 9 489 1.0E-71 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS10400 e950e50801c3cee2091783ef18714073 490 Pfam PF13520 Amino acid permease 28 455 7.5E-58 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS06090 114617b26c515913dbce2ff137510758 121 Pfam PF01740 STAS domain 4 104 2.1E-10 T 29-03-2018 IPR002645 STAS domain CB4_RS06090 114617b26c515913dbce2ff137510758 121 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 7 102 3.5E-16 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CB4_RS06090 114617b26c515913dbce2ff137510758 121 Gene3D G3DSA:3.30.750.24 1 107 3.7E-16 T 29-03-2018 IPR002645 STAS domain CB4_RS06090 114617b26c515913dbce2ff137510758 121 SUPERFAMILY SSF52091 4 106 1.29E-17 T 29-03-2018 IPR002645 STAS domain CB4_RS05140 7454f12743280294b32512a75ce9d9ed 304 Gene3D G3DSA:1.20.1260.10 38 304 1.4E-51 T 29-03-2018 IPR012347 Ferritin-related CB4_RS05140 7454f12743280294b32512a75ce9d9ed 304 PIRSF PIRSF037834 38 304 2.5E-84 T 29-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CB4_RS05140 7454f12743280294b32512a75ce9d9ed 304 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 57 304 2.7E-69 T 29-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CB4_RS05140 7454f12743280294b32512a75ce9d9ed 304 Pfam PF05138 Phenylacetic acid catabolic protein 42 304 3.9E-66 T 29-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CB4_RS05140 7454f12743280294b32512a75ce9d9ed 304 SUPERFAMILY SSF47240 48 297 5.68E-58 T 29-03-2018 IPR009078 Ferritin-like superfamily CB4_RS13105 637b2c6634d10d0ddeae60126824edb5 396 SUPERFAMILY SSF103473 15 392 3.79E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS13105 637b2c6634d10d0ddeae60126824edb5 396 Pfam PF07690 Major Facilitator Superfamily 278 391 5.5E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS13105 637b2c6634d10d0ddeae60126824edb5 396 Pfam PF07690 Major Facilitator Superfamily 18 267 2.9E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS13105 637b2c6634d10d0ddeae60126824edb5 396 Gene3D G3DSA:1.20.1250.20 7 204 1.2E-28 T 29-03-2018 CB4_RS13105 637b2c6634d10d0ddeae60126824edb5 396 Gene3D G3DSA:1.20.1250.20 210 394 4.3E-16 T 29-03-2018 CB4_RS14655 0e9e008fe356bd815325cd663f624942 190 SUPERFAMILY SSF55729 8 181 5.5E-52 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS14655 0e9e008fe356bd815325cd663f624942 190 Gene3D G3DSA:3.40.630.30 1 188 1.9E-31 T 29-03-2018 CB4_RS14655 0e9e008fe356bd815325cd663f624942 190 Pfam PF13302 Acetyltransferase (GNAT) domain 15 156 1.0E-33 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS07530 7cbaacbeae92db9f8c0ba3d05351e9c6 268 Pfam PF00795 Carbon-nitrogen hydrolase 7 250 7.0E-47 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CB4_RS07530 7cbaacbeae92db9f8c0ba3d05351e9c6 268 Gene3D G3DSA:3.60.110.10 1 265 7.6E-77 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CB4_RS07530 7cbaacbeae92db9f8c0ba3d05351e9c6 268 SUPERFAMILY SSF56317 2 266 2.22E-72 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CB4_RS15465 b2fcf55a0bcffda766c9440b62cfe6be 450 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 182 343 2.0E-13 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain CB4_RS15465 b2fcf55a0bcffda766c9440b62cfe6be 450 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 341 445 3.0E-6 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain CB4_RS15465 b2fcf55a0bcffda766c9440b62cfe6be 450 Pfam PF17482 Phage tail sheath C-terminal domain 353 449 3.1E-9 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain CB4_RS08940 0d8f5eba0b7b8ecf6c5c50c8d6b6a1ae 187 Pfam PF04630 Phage tail tube protein 25 181 8.7E-6 T 29-03-2018 IPR006724 Phage tail tube protein 1 CB4_RS08940 0d8f5eba0b7b8ecf6c5c50c8d6b6a1ae 187 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 4 184 4.8E-50 T 29-03-2018 IPR006490 Phage major tail protein, phi13 family CB4_RS04450 c1c7e5c6556e4d22011adb93dfc05c7e 118 SUPERFAMILY SSF52833 3 115 2.64E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS04450 c1c7e5c6556e4d22011adb93dfc05c7e 118 Pfam PF03960 ArsC family 44 114 2.5E-16 T 29-03-2018 IPR006660 Arsenate reductase-like CB4_RS04450 c1c7e5c6556e4d22011adb93dfc05c7e 118 Gene3D G3DSA:3.40.30.10 1 117 3.8E-35 T 29-03-2018 CB4_RS04450 c1c7e5c6556e4d22011adb93dfc05c7e 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 117 8.8E-35 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CB4_RS15910 6be78c9f11d877b0b0ffc6c7790a9ab0 224 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 78 93 5.0E-16 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CB4_RS15910 6be78c9f11d877b0b0ffc6c7790a9ab0 224 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 143 158 5.0E-16 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CB4_RS15910 6be78c9f11d877b0b0ffc6c7790a9ab0 224 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 104 116 5.0E-16 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CB4_RS15910 6be78c9f11d877b0b0ffc6c7790a9ab0 224 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 65 217 1.5E-44 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CB4_RS15910 6be78c9f11d877b0b0ffc6c7790a9ab0 224 SUPERFAMILY SSF50891 63 221 5.41E-52 T 29-03-2018 IPR029000 Cyclophilin-like domain CB4_RS15910 6be78c9f11d877b0b0ffc6c7790a9ab0 224 PIRSF PIRSF001467 51 224 3.5E-46 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CB4_RS15910 6be78c9f11d877b0b0ffc6c7790a9ab0 224 Gene3D G3DSA:2.40.100.10 42 224 8.2E-57 T 29-03-2018 IPR029000 Cyclophilin-like domain CB4_RS15535 b93ca07c18f67d223fbcb58b2c2fd4a3 88 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 6 83 1.0E-13 T 29-03-2018 IPR007347 Sporulation stage V, protein S CB4_RS15535 b93ca07c18f67d223fbcb58b2c2fd4a3 88 Pfam PF04232 Stage V sporulation protein S (SpoVS) 6 83 3.6E-20 T 29-03-2018 IPR007347 Sporulation stage V, protein S CB4_RS14195 d1dec2b09f9f3ae20e7fc530cd9d8ec5 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 218 1.9E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS14195 d1dec2b09f9f3ae20e7fc530cd9d8ec5 220 Gene3D G3DSA:1.10.3720.10 4 220 1.8E-39 T 29-03-2018 CB4_RS14195 d1dec2b09f9f3ae20e7fc530cd9d8ec5 220 SUPERFAMILY SSF161098 9 204 2.75E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS06135 0f9e79387e88520562706ecf69a8531b 427 ProSitePatterns PS01276 Peptidase family U32 signature. 173 191 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CB4_RS06135 0f9e79387e88520562706ecf69a8531b 427 Pfam PF01136 Peptidase family U32 88 327 6.1E-91 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CB4_RS06135 0f9e79387e88520562706ecf69a8531b 427 Pfam PF16325 Peptidase family U32 C-terminal domain 342 423 6.2E-28 T 29-03-2018 IPR032525 Peptidase family U32, C-terminal CB4_RS06135 0f9e79387e88520562706ecf69a8531b 427 SUPERFAMILY SSF51395 19 156 1.74E-5 T 29-03-2018 CB4_RS06135 0f9e79387e88520562706ecf69a8531b 427 Gene3D G3DSA:3.20.20.70 6 180 3.0E-11 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS07485 0b8af3b0bd742163077916630d9f0325 136 SUPERFAMILY SSF46785 20 110 2.67E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07485 0b8af3b0bd742163077916630d9f0325 136 Pfam PF03551 Transcriptional regulator PadR-like family 27 97 1.5E-20 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CB4_RS07485 0b8af3b0bd742163077916630d9f0325 136 Gene3D G3DSA:1.10.10.10 12 109 1.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07485 0b8af3b0bd742163077916630d9f0325 136 TIGRFAM TIGR02719 repress_PhaQ: poly-beta-hydroxybutyrate-responsive repressor 7 134 3.3E-43 T 29-03-2018 IPR014091 Transcriptional repressor poly-beta-hydroxybutyrate-responsive CB4_RS18350 55ac81b4c198c77d984ffc7b7e7cb6c2 202 SUPERFAMILY SSF52540 1 193 7.8E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS18350 55ac81b4c198c77d984ffc7b7e7cb6c2 202 Gene3D G3DSA:3.40.50.300 1 202 1.6E-48 T 29-03-2018 CB4_RS18350 55ac81b4c198c77d984ffc7b7e7cb6c2 202 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 197 27.66 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CB4_RS18350 55ac81b4c198c77d984ffc7b7e7cb6c2 202 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 188 5.8E-63 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CB4_RS18350 55ac81b4c198c77d984ffc7b7e7cb6c2 202 Pfam PF01121 Dephospho-CoA kinase 2 181 6.5E-61 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CB4_RS07430 a1a9983240e0ab0e58c4926653b0a9e8 448 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 423 1.4E-132 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CB4_RS07430 a1a9983240e0ab0e58c4926653b0a9e8 448 Pfam PF05525 Branched-chain amino acid transport protein 8 434 6.1E-143 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CB4_RS16325 ffbd84cff95894d77b50b9f4b16dd296 176 Gene3D G3DSA:3.90.79.10 1 176 2.4E-43 T 29-03-2018 CB4_RS16325 ffbd84cff95894d77b50b9f4b16dd296 176 SUPERFAMILY SSF55811 4 172 5.15E-52 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CB4_RS16325 ffbd84cff95894d77b50b9f4b16dd296 176 Pfam PF00293 NUDIX domain 40 152 4.7E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CB4_RS16325 ffbd84cff95894d77b50b9f4b16dd296 176 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CB4_RS01415 a2c721801bb2293205ac920fc266bc1b 180 Pfam PF14103 Domain of unknown function (DUF4276) 5 176 4.6E-18 T 29-03-2018 IPR025455 Protein of unknown function DUF4276 CB4_RS06450 757610e3ce511db8fb4cafe13e6aee1c 255 Pfam PF01925 Sulfite exporter TauE/SafE 13 245 3.2E-44 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CB4_RS01785 24fcd1ae77508e2d94318f046ba852bb 367 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 17 360 2.3E-64 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CB4_RS01785 24fcd1ae77508e2d94318f046ba852bb 367 SUPERFAMILY SSF111342 3 288 4.18E-83 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CB4_RS01785 24fcd1ae77508e2d94318f046ba852bb 367 PIRSF PIRSF026782 5 366 1.3E-122 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CB4_RS01785 24fcd1ae77508e2d94318f046ba852bb 367 Pfam PF01888 CbiD 9 270 3.8E-94 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CB4_RS01785 24fcd1ae77508e2d94318f046ba852bb 367 Gene3D G3DSA:3.30.2110.10 11 183 1.7E-63 T 29-03-2018 CB4_RS01785 24fcd1ae77508e2d94318f046ba852bb 367 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 9 361 28.617 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CB4_RS20120 b36814fa3a78c4204772e00fae99d699 173 SUPERFAMILY SSF160631 44 172 1.24E-12 T 29-03-2018 CB4_RS20120 b36814fa3a78c4204772e00fae99d699 173 SMART SM00860 44 136 8.0E-7 T 29-03-2018 IPR018958 Knr4/Smi1-like domain CB4_RS20120 b36814fa3a78c4204772e00fae99d699 173 Gene3D G3DSA:3.40.1580.10 35 173 8.5E-16 T 29-03-2018 CB4_RS20120 b36814fa3a78c4204772e00fae99d699 173 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 44 136 3.8E-10 T 29-03-2018 IPR018958 Knr4/Smi1-like domain CB4_RS03830 38897e402e81389d8b9e25fad8a2fdfd 281 Gene3D G3DSA:3.40.50.1820 3 281 1.3E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS03830 38897e402e81389d8b9e25fad8a2fdfd 281 SUPERFAMILY SSF53474 10 280 2.91E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS03830 38897e402e81389d8b9e25fad8a2fdfd 281 Pfam PF01738 Dienelactone hydrolase family 24 279 2.8E-9 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CB4_RS13970 8efd145e3379dfa4a08d0e83ffac125f 366 SUPERFAMILY SSF53383 7 364 1.24E-117 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS13970 8efd145e3379dfa4a08d0e83ffac125f 366 Gene3D G3DSA:3.90.1150.10 263 364 3.3E-39 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS13970 8efd145e3379dfa4a08d0e83ffac125f 366 Pfam PF00266 Aminotransferase class-V 9 350 5.1E-53 T 29-03-2018 IPR000192 Aminotransferase class V domain CB4_RS13970 8efd145e3379dfa4a08d0e83ffac125f 366 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 6 365 50.16 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CB4_RS13970 8efd145e3379dfa4a08d0e83ffac125f 366 Gene3D G3DSA:3.40.640.10 20 262 2.2E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS13970 8efd145e3379dfa4a08d0e83ffac125f 366 PIRSF PIRSF000525 2 366 1.2E-155 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CB4_RS13970 8efd145e3379dfa4a08d0e83ffac125f 366 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 9 365 3.6E-157 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CB4_RS14425 aae318edb88c2af3a556a3428e011437 444 PRINTS PR00758 Arsenical pump membrane protein signature 292 316 1.3E-38 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS14425 aae318edb88c2af3a556a3428e011437 444 PRINTS PR00758 Arsenical pump membrane protein signature 379 404 1.3E-38 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS14425 aae318edb88c2af3a556a3428e011437 444 PRINTS PR00758 Arsenical pump membrane protein signature 412 436 1.3E-38 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS14425 aae318edb88c2af3a556a3428e011437 444 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 1.3E-38 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS14425 aae318edb88c2af3a556a3428e011437 444 PRINTS PR00758 Arsenical pump membrane protein signature 338 360 1.3E-38 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS14425 aae318edb88c2af3a556a3428e011437 444 Pfam PF02040 Arsenical pump membrane protein 5 440 2.0E-69 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS14255 900d1f7b0c5d414f057152ce9f152128 271 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 3 252 2.6E-24 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CB4_RS14390 69202ce32f61e5db446ac976a46348e0 256 Gene3D G3DSA:3.40.190.10 129 214 2.2E-26 T 29-03-2018 CB4_RS14390 69202ce32f61e5db446ac976a46348e0 256 SMART SM00062 30 252 1.4E-72 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CB4_RS14390 69202ce32f61e5db446ac976a46348e0 256 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 251 1.1E-67 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CB4_RS14390 69202ce32f61e5db446ac976a46348e0 256 SUPERFAMILY SSF53850 1 252 7.56E-68 T 29-03-2018 CB4_RS14390 69202ce32f61e5db446ac976a46348e0 256 Gene3D G3DSA:3.40.190.10 20 128 4.7E-29 T 29-03-2018 CB4_RS14390 69202ce32f61e5db446ac976a46348e0 256 SMART SM00079 32 251 0.0092 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CB4_RS09395 230136465f708e99fabca97d99da3348 339 Gene3D G3DSA:3.40.50.720 3 334 1.1E-63 T 29-03-2018 CB4_RS09395 230136465f708e99fabca97d99da3348 339 SUPERFAMILY SSF51735 296 331 3.75E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS09395 230136465f708e99fabca97d99da3348 339 SUPERFAMILY SSF51735 4 266 3.75E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS09395 230136465f708e99fabca97d99da3348 339 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 230 2.0E-36 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CB4_RS16180 a740084c03ca03079fc8bfe29462dc7f 339 SUPERFAMILY SSF53901 57 313 3.9E-15 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS16180 a740084c03ca03079fc8bfe29462dc7f 339 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 8 334 3.2E-153 T 29-03-2018 IPR010894 Stage V sporulation AD CB4_RS16180 a740084c03ca03079fc8bfe29462dc7f 339 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 7 334 5.7E-151 T 29-03-2018 IPR010894 Stage V sporulation AD CB4_RS16180 a740084c03ca03079fc8bfe29462dc7f 339 Gene3D G3DSA:3.40.47.10 21 238 1.8E-8 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CB4_RS16180 a740084c03ca03079fc8bfe29462dc7f 339 PIRSF PIRSF011570 3 337 3.3E-153 T 29-03-2018 IPR010894 Stage V sporulation AD CB4_RS04315 f1445be055edbd7cf1094e0dbd4ec19b 89 SUPERFAMILY SSF46785 8 75 8.35E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04315 f1445be055edbd7cf1094e0dbd4ec19b 89 Gene3D G3DSA:1.10.10.10 14 77 8.1E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04315 f1445be055edbd7cf1094e0dbd4ec19b 89 Pfam PF13730 Helix-turn-helix domain 11 64 9.0E-9 T 29-03-2018 CB4_RS06985 7633e29be42659140b990ed7225f1dd0 471 SMART SM00345 17 76 3.5E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS06985 7633e29be42659140b990ed7225f1dd0 471 Pfam PF00155 Aminotransferase class I and II 130 463 1.2E-33 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS06985 7633e29be42659140b990ed7225f1dd0 471 Gene3D G3DSA:1.10.10.10 1 78 5.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS06985 7633e29be42659140b990ed7225f1dd0 471 SUPERFAMILY SSF53383 101 469 1.31E-88 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS06985 7633e29be42659140b990ed7225f1dd0 471 SUPERFAMILY SSF46785 6 78 3.02E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS06985 7633e29be42659140b990ed7225f1dd0 471 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 5.7E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS06985 7633e29be42659140b990ed7225f1dd0 471 Gene3D G3DSA:3.40.640.10 142 350 3.7E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS06985 7633e29be42659140b990ed7225f1dd0 471 Gene3D G3DSA:3.90.1150.10 351 471 8.8E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS06985 7633e29be42659140b990ed7225f1dd0 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 8.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS06985 7633e29be42659140b990ed7225f1dd0 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 8.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CB4_RS00505 8108115495fec577daf42321b7549eec 499 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 444 486 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CB4_RS00505 8108115495fec577daf42321b7549eec 499 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 459 474 7.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CB4_RS00505 8108115495fec577daf42321b7549eec 499 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 474 490 7.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CB4_RS00505 8108115495fec577daf42321b7549eec 499 SMART SM00448 1 114 9.2E-6 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS00505 8108115495fec577daf42321b7549eec 499 Gene3D G3DSA:1.10.10.60 447 499 2.2E-17 T 29-03-2018 CB4_RS00505 8108115495fec577daf42321b7549eec 499 Pfam PF00072 Response regulator receiver domain 4 113 1.5E-9 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS00505 8108115495fec577daf42321b7549eec 499 Pfam PF12833 Helix-turn-helix domain 414 491 4.3E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CB4_RS00505 8108115495fec577daf42321b7549eec 499 SUPERFAMILY SSF46689 443 492 1.03E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS00505 8108115495fec577daf42321b7549eec 499 Gene3D G3DSA:2.60.120.10 260 446 1.8E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS00505 8108115495fec577daf42321b7549eec 499 SMART SM00342 407 490 2.6E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CB4_RS00505 8108115495fec577daf42321b7549eec 499 SUPERFAMILY SSF52172 1 141 2.42E-16 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS00505 8108115495fec577daf42321b7549eec 499 Gene3D G3DSA:3.40.50.2300 1 227 2.6E-16 T 29-03-2018 CB4_RS18595 64dec9c239be770f918d2ff005e1aea2 175 Pfam PF12840 Helix-turn-helix domain 4 59 6.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18595 64dec9c239be770f918d2ff005e1aea2 175 Gene3D G3DSA:1.10.10.10 1 79 5.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18595 64dec9c239be770f918d2ff005e1aea2 175 SMART SM00418 2 86 4.4E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS18595 64dec9c239be770f918d2ff005e1aea2 175 SUPERFAMILY SSF46785 3 115 1.23E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04290 1aeaee1ea36fed13c549403a42bfb628 192 SUPERFAMILY SSF53254 1 191 1.44E-48 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CB4_RS04290 1aeaee1ea36fed13c549403a42bfb628 192 SMART SM00855 2 157 4.1E-19 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CB4_RS04290 1aeaee1ea36fed13c549403a42bfb628 192 PIRSF PIRSF000709 1 172 1.1E-12 T 29-03-2018 CB4_RS04290 1aeaee1ea36fed13c549403a42bfb628 192 Gene3D G3DSA:3.40.50.1240 1 192 6.4E-50 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CB4_RS04290 1aeaee1ea36fed13c549403a42bfb628 192 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 191 7.9E-47 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CB4_RS11220 264bb1a9562f9bc1e1acee7f62df3dbb 343 Gene3D G3DSA:3.40.50.720 7 194 5.7E-37 T 29-03-2018 CB4_RS11220 264bb1a9562f9bc1e1acee7f62df3dbb 343 PRINTS PR01713 Nucleotide sugar epimerase signature 222 237 2.1E-30 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CB4_RS11220 264bb1a9562f9bc1e1acee7f62df3dbb 343 PRINTS PR01713 Nucleotide sugar epimerase signature 301 318 2.1E-30 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CB4_RS11220 264bb1a9562f9bc1e1acee7f62df3dbb 343 PRINTS PR01713 Nucleotide sugar epimerase signature 262 277 2.1E-30 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CB4_RS11220 264bb1a9562f9bc1e1acee7f62df3dbb 343 PRINTS PR01713 Nucleotide sugar epimerase signature 35 51 2.1E-30 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CB4_RS11220 264bb1a9562f9bc1e1acee7f62df3dbb 343 SUPERFAMILY SSF51735 7 339 4.51E-93 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS11220 264bb1a9562f9bc1e1acee7f62df3dbb 343 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 267 2.4E-54 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CB4_RS11220 264bb1a9562f9bc1e1acee7f62df3dbb 343 Gene3D G3DSA:3.90.25.10 195 342 6.5E-41 T 29-03-2018 CB4_RS02635 e8e451ffc3c5f3ef246e554eb1555365 430 Gene3D G3DSA:3.40.50.150 178 430 3.1E-40 T 29-03-2018 CB4_RS02635 e8e451ffc3c5f3ef246e554eb1555365 430 Pfam PF03602 Conserved hypothetical protein 95 252 339 5.8E-12 T 29-03-2018 CB4_RS02635 e8e451ffc3c5f3ef246e554eb1555365 430 SMART SM00359 2 87 2.6E-8 T 29-03-2018 IPR002478 PUA domain GO:0003723 CB4_RS02635 e8e451ffc3c5f3ef246e554eb1555365 430 SUPERFAMILY SSF88697 2 71 3.54E-18 T 29-03-2018 IPR015947 PUA-like domain CB4_RS02635 e8e451ffc3c5f3ef246e554eb1555365 430 Gene3D G3DSA:2.30.130.10 3 66 1.9E-25 T 29-03-2018 IPR002478 PUA domain GO:0003723 CB4_RS02635 e8e451ffc3c5f3ef246e554eb1555365 430 SUPERFAMILY SSF53335 94 204 6.57E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS02635 e8e451ffc3c5f3ef246e554eb1555365 430 SUPERFAMILY SSF53335 234 421 6.57E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS02635 e8e451ffc3c5f3ef246e554eb1555365 430 Gene3D G3DSA:3.30.750.80 73 177 3.9E-32 T 29-03-2018 CB4_RS09900 248b33b11dca348dfcb4bdb8f77b2d99 401 Gene3D G3DSA:1.20.1250.20 202 396 1.2E-17 T 29-03-2018 CB4_RS09900 248b33b11dca348dfcb4bdb8f77b2d99 401 SUPERFAMILY SSF103473 9 393 1.02E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS09900 248b33b11dca348dfcb4bdb8f77b2d99 401 Gene3D G3DSA:1.20.1250.20 2 200 4.1E-23 T 29-03-2018 CB4_RS09900 248b33b11dca348dfcb4bdb8f77b2d99 401 Pfam PF07690 Major Facilitator Superfamily 27 324 1.7E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS11585 9e2903f81cc099d003aa41847285126c 441 ProSitePatterns PS00018 EF-hand calcium-binding domain. 67 79 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site CB4_RS04000 a26c9b1ff77ce0f3eb483697a51248c5 325 SUPERFAMILY SSF51735 110 285 7.4E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS04000 a26c9b1ff77ce0f3eb483697a51248c5 325 Gene3D G3DSA:3.90.180.10 1 131 9.1E-37 T 29-03-2018 CB4_RS04000 a26c9b1ff77ce0f3eb483697a51248c5 325 Gene3D G3DSA:3.90.180.10 294 324 0.1 T 29-03-2018 CB4_RS04000 a26c9b1ff77ce0f3eb483697a51248c5 325 Pfam PF00107 Zinc-binding dehydrogenase 149 266 9.9E-29 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CB4_RS04000 a26c9b1ff77ce0f3eb483697a51248c5 325 SMART SM00829 8 322 6.1E-56 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CB4_RS04000 a26c9b1ff77ce0f3eb483697a51248c5 325 SUPERFAMILY SSF50129 1 138 3.77E-37 T 29-03-2018 IPR011032 GroES-like CB4_RS04000 a26c9b1ff77ce0f3eb483697a51248c5 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 85 1.5E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CB4_RS04000 a26c9b1ff77ce0f3eb483697a51248c5 325 Gene3D G3DSA:3.40.50.720 132 293 2.7E-40 T 29-03-2018 CB4_RS04000 a26c9b1ff77ce0f3eb483697a51248c5 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 323 3.2E-122 T 29-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CB4_RS19660 af060366b976fdbce6252a179e450138 132 Pfam PF01381 Helix-turn-helix 12 65 3.1E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS19660 af060366b976fdbce6252a179e450138 132 SUPERFAMILY SSF47413 5 71 2.6E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS19660 af060366b976fdbce6252a179e450138 132 SMART SM00530 10 65 8.9E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS19660 af060366b976fdbce6252a179e450138 132 Gene3D G3DSA:1.10.260.40 1 129 4.8E-18 T 29-03-2018 CB4_RS00090 7947726c166502922d136999970e2b78 496 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 31 482 1.9E-149 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS00090 7947726c166502922d136999970e2b78 496 PIRSF PIRSF005690 19 496 3.1E-150 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 SUPERFAMILY SSF47757 1 68 1.09E-12 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 Gene3D G3DSA:3.40.50.150 68 258 6.3E-50 T 29-03-2018 CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 PRINTS PR00996 Glutamate methyltransferase family signature 131 147 2.3E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 PRINTS PR00996 Glutamate methyltransferase family signature 216 239 2.3E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 PRINTS PR00996 Glutamate methyltransferase family signature 197 211 2.3E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 PRINTS PR00996 Glutamate methyltransferase family signature 25 38 2.3E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 PRINTS PR00996 Glutamate methyltransferase family signature 62 74 2.3E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 PRINTS PR00996 Glutamate methyltransferase family signature 99 119 2.3E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 Gene3D G3DSA:1.10.155.10 1 67 2.9E-13 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 Pfam PF03705 CheR methyltransferase, all-alpha domain 5 52 2.3E-13 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 SMART SM00138 3 256 1.9E-97 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 SUPERFAMILY SSF53335 69 256 5.85E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS15150 dabd4b5026c6abcf1835735e5a6b6e33 258 Pfam PF01739 CheR methyltransferase, SAM binding domain 69 244 1.0E-58 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CB4_RS09965 5c8c5909cee6bc08435bee77ab26d685 187 Pfam PF03358 NADPH-dependent FMN reductase 42 104 1.3E-9 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CB4_RS09965 5c8c5909cee6bc08435bee77ab26d685 187 Gene3D G3DSA:3.40.50.360 1 182 3.0E-37 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS09965 5c8c5909cee6bc08435bee77ab26d685 187 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CB4_RS09965 5c8c5909cee6bc08435bee77ab26d685 187 SUPERFAMILY SSF52218 1 176 7.47E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS05055 dd698b55006b82b8fb59f2e5fdcae7c6 166 Pfam PF04608 Phosphatidylglycerophosphatase A 23 159 2.5E-19 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CB4_RS05055 dd698b55006b82b8fb59f2e5fdcae7c6 166 SUPERFAMILY SSF101307 13 162 1.15E-53 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CB4_RS05055 dd698b55006b82b8fb59f2e5fdcae7c6 166 Gene3D G3DSA:1.10.3760.10 1 166 8.0E-59 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CB4_RS05055 dd698b55006b82b8fb59f2e5fdcae7c6 166 PIRSF PIRSF019587 5 166 5.3E-74 T 29-03-2018 IPR026038 Putative phosphatidylglycerophosphatase CB4_RS15200 5bca0cf9048604067a61e9b3669d9a6e 492 PIRSF PIRSF007466 1 492 1.3E-255 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CB4_RS15200 5bca0cf9048604067a61e9b3669d9a6e 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 5.9E-225 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CB4_RS15200 5bca0cf9048604067a61e9b3669d9a6e 492 Gene3D G3DSA:3.40.50.300 7 435 1.2E-13 T 29-03-2018 CB4_RS15200 5bca0cf9048604067a61e9b3669d9a6e 492 SUPERFAMILY SSF52540 4 274 3.01E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS15200 5bca0cf9048604067a61e9b3669d9a6e 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 2 492 5.4E-253 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CB4_RS12315 43c07ed21155496ed9cbc2838efc7fd0 491 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 15 460 2.0E-122 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 CB4_RS12315 43c07ed21155496ed9cbc2838efc7fd0 491 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 10 477 46.351 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 CB4_RS16050 79b5e8cff7e7d98d82deeeaf8e335fcf 125 Pfam PF01986 Domain of unknown function DUF123 34 120 1.9E-19 T 29-03-2018 IPR002837 Protein of unknown function DUF123 CB4_RS10480 ff51da849f528f36f6d63d8268cb37a9 316 SUPERFAMILY SSF103481 219 294 9.02E-7 T 29-03-2018 CB4_RS10480 ff51da849f528f36f6d63d8268cb37a9 316 TIGRFAM TIGR00688 rarD: protein RarD 15 268 2.5E-77 T 29-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 CB4_RS10480 ff51da849f528f36f6d63d8268cb37a9 316 Pfam PF00892 EamA-like transporter family 160 292 3.6E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS10480 ff51da849f528f36f6d63d8268cb37a9 316 Pfam PF00892 EamA-like transporter family 15 150 6.4E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS10480 ff51da849f528f36f6d63d8268cb37a9 316 SUPERFAMILY SSF103481 52 152 4.32E-13 T 29-03-2018 CB4_RS07510 c4b5dd59326074a0bed6167fb85bb64a 252 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 8 245 7.8E-72 T 29-03-2018 IPR005226 UPF0014 family CB4_RS07510 c4b5dd59326074a0bed6167fb85bb64a 252 Pfam PF03649 Uncharacterised protein family (UPF0014) 5 240 1.2E-71 T 29-03-2018 IPR005226 UPF0014 family CB4_RS12940 caacf3808277dc25f123ed8ca341ece1 218 Pfam PF09335 SNARE associated Golgi protein 70 183 5.3E-21 T 29-03-2018 IPR032816 SNARE associated Golgi protein CB4_RS14980 70ecfbe6eb71bfb8d3b6edf7779f3e56 402 SUPERFAMILY SSF81301 10 139 7.08E-44 T 29-03-2018 CB4_RS14980 70ecfbe6eb71bfb8d3b6edf7779f3e56 402 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 251 393 9.8E-20 T 29-03-2018 IPR032810 CCA-adding enzyme, C-terminal CB4_RS14980 70ecfbe6eb71bfb8d3b6edf7779f3e56 402 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 171 228 4.1E-12 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CB4_RS14980 70ecfbe6eb71bfb8d3b6edf7779f3e56 402 Gene3D G3DSA:3.30.460.10 2 142 2.2E-47 T 29-03-2018 CB4_RS14980 70ecfbe6eb71bfb8d3b6edf7779f3e56 402 SUPERFAMILY SSF81891 141 399 2.88E-43 T 29-03-2018 CB4_RS14980 70ecfbe6eb71bfb8d3b6edf7779f3e56 402 Pfam PF01743 Poly A polymerase head domain 23 143 1.8E-36 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CB4_RS14980 70ecfbe6eb71bfb8d3b6edf7779f3e56 402 Gene3D G3DSA:1.10.3090.10 143 399 4.0E-36 T 29-03-2018 CB4_RS01765 1260a033e9dbcdbb2a66e34101fe2e94 380 SUPERFAMILY SSF159672 21 266 3.4E-57 T 29-03-2018 CB4_RS01765 1260a033e9dbcdbb2a66e34101fe2e94 380 Gene3D G3DSA:3.30.420.180 249 377 1.3E-35 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CB4_RS01765 1260a033e9dbcdbb2a66e34101fe2e94 380 SUPERFAMILY SSF159664 252 378 4.05E-36 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CB4_RS01765 1260a033e9dbcdbb2a66e34101fe2e94 380 Pfam PF01890 Cobalamin synthesis G C-terminus 259 375 4.7E-33 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CB4_RS01765 1260a033e9dbcdbb2a66e34101fe2e94 380 Pfam PF11760 Cobalamin synthesis G N-terminal 76 154 5.3E-34 T 29-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 CB4_RS01765 1260a033e9dbcdbb2a66e34101fe2e94 380 Pfam PF11761 Cobalamin biosynthesis central region 160 256 2.5E-12 T 29-03-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 CB4_RS18530 303cadf3b062078da1f82a4c15caac2a 154 SUPERFAMILY SSF55729 44 125 4.77E-7 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS18530 303cadf3b062078da1f82a4c15caac2a 154 Gene3D G3DSA:3.40.630.30 1 141 1.6E-6 T 29-03-2018 CB4_RS16975 ae9e8a454f7c62935bcf8e66f3eaefe0 231 Pfam PF03475 3-alpha domain 173 214 1.2E-14 T 29-03-2018 IPR005163 3-alpha domain CB4_RS16975 ae9e8a454f7c62935bcf8e66f3eaefe0 231 SUPERFAMILY SSF50800 2 217 4.88E-72 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CB4_RS16975 ae9e8a454f7c62935bcf8e66f3eaefe0 231 Pfam PF03473 MOSC domain 50 157 7.9E-25 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CB4_RS16975 ae9e8a454f7c62935bcf8e66f3eaefe0 231 Gene3D G3DSA:2.40.33.20 1 230 3.9E-51 T 29-03-2018 CB4_RS15670 9ecba16c9cd86acdc7c4e346b8fbf504 137 Pfam PF08896 Domain of unknown function (DUF1842) 7 121 1.7E-31 T 29-03-2018 IPR014992 Domain of unknown function DUF1842 CB4_RS02495 f03b55be29d2cca2c68f0f01bded3ccd 203 SUPERFAMILY SSF50486 2 202 4.08E-69 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CB4_RS02495 f03b55be29d2cca2c68f0f01bded3ccd 203 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 6 198 1.7E-63 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CB4_RS02495 f03b55be29d2cca2c68f0f01bded3ccd 203 Gene3D G3DSA:3.10.300.10 1 203 1.8E-73 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CB4_RS02495 f03b55be29d2cca2c68f0f01bded3ccd 203 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 5 201 35.802 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CB4_RS02495 f03b55be29d2cca2c68f0f01bded3ccd 203 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 3 201 9.5E-64 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 Pfam PF00395 S-layer homology domain 171 214 3.9E-7 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 Pfam PF00395 S-layer homology domain 47 91 2.8E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 Pfam PF00395 S-layer homology domain 109 152 7.4E-12 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 SMART SM00635 711 793 2.1 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 SMART SM00635 626 700 7.1 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 SMART SM00635 534 615 0.26 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 Gene3D G3DSA:2.60.40.10 710 801 1.8E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 Gene3D G3DSA:2.60.40.10 624 709 0.0039 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 Gene3D G3DSA:2.60.40.10 802 897 5.0E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 Gene3D G3DSA:2.60.40.10 526 623 3.7E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS18760 e872f60bc7932ce288cdbe383bb11119 1079 Gene3D G3DSA:2.60.40.10 898 994 1.3E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS05480 fe3f6fba77df79e52df495b6ef046763 261 Gene3D G3DSA:1.10.12.10 219 261 3.1E-15 T 29-03-2018 IPR014748 Crontonase, C-terminal CB4_RS05480 fe3f6fba77df79e52df495b6ef046763 261 Gene3D G3DSA:3.90.226.10 5 218 5.5E-66 T 29-03-2018 CB4_RS05480 fe3f6fba77df79e52df495b6ef046763 261 SUPERFAMILY SSF52096 1 259 5.14E-80 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS05480 fe3f6fba77df79e52df495b6ef046763 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 261 8.9E-58 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CB4_RS05480 fe3f6fba77df79e52df495b6ef046763 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CB4_RS10940 f3eb94a75aa557e54c273f26620cdd4a 322 SUPERFAMILY SSF56601 11 322 8.91E-119 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS10940 f3eb94a75aa557e54c273f26620cdd4a 322 Hamap MF_00313 Glutaminase [glsA]. 8 322 44.99 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CB4_RS10940 f3eb94a75aa557e54c273f26620cdd4a 322 Pfam PF04960 Glutaminase 26 322 8.3E-108 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CB4_RS10940 f3eb94a75aa557e54c273f26620cdd4a 322 TIGRFAM TIGR03814 Gln_ase: glutaminase A 12 322 7.0E-120 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CB4_RS10940 f3eb94a75aa557e54c273f26620cdd4a 322 Gene3D G3DSA:3.40.710.10 2 322 1.8E-117 T 29-03-2018 CB4_RS01525 0461d695089802289ca72f004a6addea 295 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 8 263 1.0E-63 T 29-03-2018 IPR008764 Peptidase U57, YabG CB4_RS01525 0461d695089802289ca72f004a6addea 295 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 6 286 1.2E-109 T 29-03-2018 IPR008764 Peptidase U57, YabG CB4_RS01525 0461d695089802289ca72f004a6addea 295 Pfam PF05582 YabG peptidase U57 6 285 7.4E-108 T 29-03-2018 IPR008764 Peptidase U57, YabG CB4_RS01525 0461d695089802289ca72f004a6addea 295 PIRSF PIRSF011575 4 289 3.3E-107 T 29-03-2018 IPR008764 Peptidase U57, YabG CB4_RS02520 cfff49b9d0d58c7cc2618af28e4a2a61 432 Pfam PF03063 Prismane/CO dehydrogenase family 80 424 3.7E-106 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 CB4_RS02520 cfff49b9d0d58c7cc2618af28e4a2a61 432 Pfam PF03063 Prismane/CO dehydrogenase family 1 79 1.3E-16 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 CB4_RS02520 cfff49b9d0d58c7cc2618af28e4a2a61 432 Gene3D G3DSA:1.20.1270.20 28 111 7.7E-30 T 29-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CB4_RS02520 cfff49b9d0d58c7cc2618af28e4a2a61 432 Gene3D G3DSA:3.40.50.2030 253 432 9.9E-57 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CB4_RS02520 cfff49b9d0d58c7cc2618af28e4a2a61 432 Gene3D G3DSA:3.40.50.2030 114 252 1.0E-62 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CB4_RS02520 cfff49b9d0d58c7cc2618af28e4a2a61 432 SUPERFAMILY SSF56821 1 427 1.83E-152 T 29-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 CB4_RS02520 cfff49b9d0d58c7cc2618af28e4a2a61 432 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 23 427 5.6E-171 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 CB4_RS02520 cfff49b9d0d58c7cc2618af28e4a2a61 432 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 428 16.779 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 CB4_RS05035 6231df07501bca40235460b28504aa55 575 Gene3D G3DSA:1.10.287.950 223 315 4.4E-4 T 29-03-2018 CB4_RS05035 6231df07501bca40235460b28504aa55 575 SUPERFAMILY SSF103190 70 180 3.1E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS05035 6231df07501bca40235460b28504aa55 575 SMART SM00304 216 270 3.0E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS05035 6231df07501bca40235460b28504aa55 575 SMART SM00283 299 574 1.3E-55 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS05035 6231df07501bca40235460b28504aa55 575 Pfam PF00672 HAMP domain 216 265 1.5E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS05035 6231df07501bca40235460b28504aa55 575 Gene3D G3DSA:1.10.287.950 321 575 8.1E-48 T 29-03-2018 CB4_RS05035 6231df07501bca40235460b28504aa55 575 SUPERFAMILY SSF58104 238 272 9.55E-65 T 29-03-2018 CB4_RS05035 6231df07501bca40235460b28504aa55 575 SUPERFAMILY SSF58104 305 573 9.55E-65 T 29-03-2018 CB4_RS05035 6231df07501bca40235460b28504aa55 575 Gene3D G3DSA:3.30.450.20 30 188 1.0E-11 T 29-03-2018 CB4_RS05035 6231df07501bca40235460b28504aa55 575 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 371 528 1.8E-39 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14835 6552b50514ac0652b18cef0d94f0b352 265 Gene3D G3DSA:3.30.70.260 14 95 2.5E-5 T 29-03-2018 CB4_RS14835 6552b50514ac0652b18cef0d94f0b352 265 SUPERFAMILY SSF55021 8 77 4.2E-7 T 29-03-2018 CB4_RS14835 6552b50514ac0652b18cef0d94f0b352 265 Pfam PF11868 Protein of unknown function (DUF3388) 81 256 4.1E-90 T 29-03-2018 IPR024514 Domain of unknown function DUF3388 CB4_RS14835 6552b50514ac0652b18cef0d94f0b352 265 PIRSF PIRSF021288 3 263 2.6E-122 T 29-03-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain CB4_RS07040 90c429a8f329f94937151af6d0b151d7 297 Gene3D G3DSA:3.40.190.10 87 173 3.9E-24 T 29-03-2018 CB4_RS07040 90c429a8f329f94937151af6d0b151d7 297 Gene3D G3DSA:3.40.190.10 174 259 6.1E-20 T 29-03-2018 CB4_RS07040 90c429a8f329f94937151af6d0b151d7 297 Pfam PF03466 LysR substrate binding domain 87 275 2.7E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CB4_RS07040 90c429a8f329f94937151af6d0b151d7 297 SUPERFAMILY SSF46785 1 110 7.71E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07040 90c429a8f329f94937151af6d0b151d7 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.4E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS07040 90c429a8f329f94937151af6d0b151d7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS07040 90c429a8f329f94937151af6d0b151d7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS07040 90c429a8f329f94937151af6d0b151d7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CB4_RS07040 90c429a8f329f94937151af6d0b151d7 297 Gene3D G3DSA:1.10.10.10 1 82 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07040 90c429a8f329f94937151af6d0b151d7 297 SUPERFAMILY SSF53850 87 293 1.66E-38 T 29-03-2018 CB4_RS12285 4debdefc3522c68d9b452a4f524ac704 197 Pfam PF09335 SNARE associated Golgi protein 29 154 8.9E-23 T 29-03-2018 IPR032816 SNARE associated Golgi protein CB4_RS04025 4eb6e07172055298bd74eb9824aa76cd 360 SUPERFAMILY SSF109604 128 297 1.31E-30 T 29-03-2018 CB4_RS04025 4eb6e07172055298bd74eb9824aa76cd 360 Gene3D G3DSA:1.10.3210.10 58 301 2.8E-37 T 29-03-2018 CB4_RS04025 4eb6e07172055298bd74eb9824aa76cd 360 Pfam PF13487 HD domain 186 248 5.6E-11 T 29-03-2018 CB4_RS04025 4eb6e07172055298bd74eb9824aa76cd 360 SMART SM00471 131 267 4.0E-8 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS04670 938f754b532a8ef1fa9dd179bc7cdadb 183 Gene3D G3DSA:3.20.20.400 1 181 2.3E-71 T 29-03-2018 CB4_RS04670 938f754b532a8ef1fa9dd179bc7cdadb 183 PIRSF PIRSF016897 1 183 2.3E-63 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CB4_RS04670 938f754b532a8ef1fa9dd179bc7cdadb 183 SUPERFAMILY SSF110391 7 182 5.23E-62 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CB4_RS04670 938f754b532a8ef1fa9dd179bc7cdadb 183 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 8 180 1.0E-63 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CB4_RS07270 184ee39b44aca855e63f9d3bc1ae3bfb 248 Gene3D G3DSA:3.20.20.140 1 246 2.5E-21 T 29-03-2018 CB4_RS07270 184ee39b44aca855e63f9d3bc1ae3bfb 248 Pfam PF04909 Amidohydrolase 6 246 1.6E-16 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CB4_RS07270 184ee39b44aca855e63f9d3bc1ae3bfb 248 SUPERFAMILY SSF51556 4 246 2.21E-41 T 29-03-2018 IPR032466 Metal-dependent hydrolase CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 SUPERFAMILY SSF58104 318 352 9.42E-69 T 29-03-2018 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 SUPERFAMILY SSF58104 385 653 9.42E-69 T 29-03-2018 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 SUPERFAMILY SSF103190 79 177 5.1E-12 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 Pfam PF02743 Cache domain 35 260 4.5E-37 T 29-03-2018 IPR033479 Double Cache domain 1 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 SMART SM00283 379 654 7.4E-66 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 438 608 1.0E-39 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 Gene3D G3DSA:1.10.287.950 408 657 1.1E-55 T 29-03-2018 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 Gene3D G3DSA:1.10.287.950 296 407 1.4E-6 T 29-03-2018 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 Gene3D G3DSA:3.30.450.20 49 153 7.3E-20 T 29-03-2018 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 SMART SM00304 298 350 1.5E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 SMART SM00304 371 424 19.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 Pfam PF00672 HAMP domain 299 345 7.3E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS16440 5e9d2d489cbde96bb8765aa0b7c42673 657 Gene3D G3DSA:3.30.450.20 154 277 3.1E-27 T 29-03-2018 CB4_RS03080 16fbbe9fe42637f41e2b0764ababadef 249 SUPERFAMILY SSF51261 131 239 1.78E-25 T 29-03-2018 IPR011055 Duplicated hybrid motif CB4_RS03080 16fbbe9fe42637f41e2b0764ababadef 249 Gene3D G3DSA:2.70.70.10 3 242 1.5E-27 T 29-03-2018 CB4_RS03080 16fbbe9fe42637f41e2b0764ababadef 249 Pfam PF01551 Peptidase family M23 138 235 4.5E-23 T 29-03-2018 IPR016047 Peptidase M23 CB4_RS05135 3b9d3d6b9f1606f42d14cfa07774bfa0 110 Pfam PF06243 Phenylacetic acid degradation B 8 94 2.0E-23 T 29-03-2018 IPR009359 Phenylacetic acid degradation B CB4_RS16195 6dd71e2eef3e9c8605d904c137b5b765 209 Gene3D G3DSA:2.60.480.10 5 94 4.3E-17 T 29-03-2018 CB4_RS16195 6dd71e2eef3e9c8605d904c137b5b765 209 Pfam PF12164 Stage V sporulation protein AA 6 90 4.9E-14 T 29-03-2018 IPR021997 Stage V sporulation protein AA CB4_RS04410 0970f82f2082ccd967bfcb27927b9cea 399 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 217 380 1.6E-23 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS04410 0970f82f2082ccd967bfcb27927b9cea 399 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 10 383 9.1E-72 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS01600 c37426d21f2e01956dd5dde96ec73cae 61 Pfam PF10764 Inhibitor of sigma-G Gin 9 53 5.0E-18 T 29-03-2018 IPR019700 Anti-sigma-G factor Gin CB4_RS09705 daf3886b649e7045ab6cc3c90b70a206 391 Pfam PF01098 Cell cycle protein 27 383 1.3E-79 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CB4_RS11420 a37e035f37e5ffbbd66ba7f3af7233fe 435 SUPERFAMILY SSF52540 167 381 1.12E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS11420 a37e035f37e5ffbbd66ba7f3af7233fe 435 Pfam PF01580 FtsK/SpoIIIE family 171 338 1.5E-21 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CB4_RS11420 a37e035f37e5ffbbd66ba7f3af7233fe 435 Gene3D G3DSA:3.40.50.300 63 382 5.3E-21 T 29-03-2018 CB4_RS11295 9503f60777d5e713c092857ef622f516 260 SUPERFAMILY SSF54197 15 134 2.21E-17 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CB4_RS11295 9503f60777d5e713c092857ef622f516 260 Gene3D G3DSA:3.30.428.10 68 137 6.0E-9 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CB4_RS11295 9503f60777d5e713c092857ef622f516 260 Gene3D G3DSA:3.30.428.10 22 67 0.35 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CB4_RS11295 9503f60777d5e713c092857ef622f516 260 Pfam PF16285 Domain of unknown function (DUF4931) 10 258 2.7E-89 T 29-03-2018 CB4_RS03375 f54da4c763008b8eb130be5a94952c25 511 Gene3D G3DSA:3.40.50.300 350 511 1.7E-18 T 29-03-2018 CB4_RS03375 f54da4c763008b8eb130be5a94952c25 511 SMART SM00490 397 475 1.0E-8 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS03375 f54da4c763008b8eb130be5a94952c25 511 Pfam PF00271 Helicase conserved C-terminal domain 366 474 4.7E-9 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS03375 f54da4c763008b8eb130be5a94952c25 511 Gene3D G3DSA:3.40.50.300 140 330 1.1E-22 T 29-03-2018 CB4_RS03375 f54da4c763008b8eb130be5a94952c25 511 SUPERFAMILY SSF52540 179 312 3.95E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03375 f54da4c763008b8eb130be5a94952c25 511 SUPERFAMILY SSF52540 343 485 3.95E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS03375 f54da4c763008b8eb130be5a94952c25 511 SMART SM00487 156 335 1.0E-14 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS03375 f54da4c763008b8eb130be5a94952c25 511 Pfam PF04851 Type III restriction enzyme, res subunit 161 310 1.3E-5 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CB4_RS01890 62da0d0ee695ddc8d4b46f11fcc7b0bc 82 Pfam PF04025 Domain of unknown function (DUF370) 2 75 1.9E-13 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CB4_RS09800 9bc85413ba334eccf5dde3f20d4c86eb 168 Pfam PF13785 Domain of unknown function (DUF4178) 28 158 1.4E-24 T 29-03-2018 IPR025235 Domain of unknown function DUF4178 CB4_RS15800 49cf5ae6eb877c0e9b9c9c8575079e1b 160 Pfam PF11188 Protein of unknown function (DUF2975) 32 160 1.5E-40 T 29-03-2018 IPR021354 Protein of unknown function DUF2975 CB4_RS18950 fd2e7267e6abcc841afd160a66ba527c 252 Gene3D G3DSA:3.40.470.10 45 250 3.3E-49 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CB4_RS18950 fd2e7267e6abcc841afd160a66ba527c 252 SUPERFAMILY SSF52141 63 247 2.45E-50 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CB4_RS18950 fd2e7267e6abcc841afd160a66ba527c 252 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 73 242 3.3E-46 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 CB4_RS18950 fd2e7267e6abcc841afd160a66ba527c 252 SMART SM00987 87 242 1.1E-27 T 29-03-2018 CB4_RS18950 fd2e7267e6abcc841afd160a66ba527c 252 SMART SM00986 87 242 1.1E-27 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CB4_RS18950 fd2e7267e6abcc841afd160a66ba527c 252 Pfam PF03167 Uracil DNA glycosylase superfamily 87 242 5.2E-37 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CB4_RS14680 634caa41c5af7c860ef877f0636ee336 103 Pfam PF10628 Outer spore coat protein E (CotE) 1 99 4.4E-20 T 29-03-2018 IPR018901 Spore coat protein CotE CB4_RS05870 51ac173fe404dc292c3426066bef47bf 196 Gene3D G3DSA:1.10.287.130 3 63 6.7E-13 T 29-03-2018 CB4_RS05870 51ac173fe404dc292c3426066bef47bf 196 SUPERFAMILY SSF55890 10 148 4.32E-22 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CB4_RS05870 51ac173fe404dc292c3426066bef47bf 196 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 8 64 5.8E-19 T 29-03-2018 CB4_RS09220 8f57d94c271194284c0d0238c1b32673 158 Gene3D G3DSA:2.40.50.180 35 87 1.2E-19 T 29-03-2018 CB4_RS09220 8f57d94c271194284c0d0238c1b32673 158 SUPERFAMILY SSF50341 9 149 1.18E-37 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS09220 8f57d94c271194284c0d0238c1b32673 158 Gene3D G3DSA:2.30.30.40 88 139 6.5E-18 T 29-03-2018 CB4_RS09220 8f57d94c271194284c0d0238c1b32673 158 Gene3D G3DSA:2.40.50.180 2 34 0.07 T 29-03-2018 CB4_RS09220 8f57d94c271194284c0d0238c1b32673 158 SMART SM00260 8 145 3.6E-36 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS09220 8f57d94c271194284c0d0238c1b32673 158 Pfam PF01584 CheW-like domain 13 147 8.6E-35 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CB4_RS10175 bf67759f43ecd36a71106b8da8344de6 456 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 14 444 4.9E-223 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CB4_RS10175 bf67759f43ecd36a71106b8da8344de6 456 Gene3D G3DSA:3.40.50.1100 235 448 7.2E-26 T 29-03-2018 CB4_RS10175 bf67759f43ecd36a71106b8da8344de6 456 SUPERFAMILY SSF53686 56 445 2.88E-57 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS10175 bf67759f43ecd36a71106b8da8344de6 456 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 80 404 4.8E-57 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CB4_RS10175 bf67759f43ecd36a71106b8da8344de6 456 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 456 253.77 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CB4_RS10175 bf67759f43ecd36a71106b8da8344de6 456 Gene3D G3DSA:3.40.50.1100 120 234 7.8E-25 T 29-03-2018 CB4_RS10175 bf67759f43ecd36a71106b8da8344de6 456 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 113 127 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CB4_RS01010 6083c122acec5f545358d907709bb5b5 104 Gene3D G3DSA:1.10.1660.10 2 100 4.3E-22 T 29-03-2018 CB4_RS01010 6083c122acec5f545358d907709bb5b5 104 SUPERFAMILY SSF46955 10 79 7.33E-17 T 29-03-2018 IPR009061 Putative DNA-binding domain CB4_RS01010 6083c122acec5f545358d907709bb5b5 104 SMART SM00422 9 77 8.1E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS01010 6083c122acec5f545358d907709bb5b5 104 Pfam PF13411 MerR HTH family regulatory protein 10 75 4.4E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CB4_RS17015 d348df1e8da4bb10648e2f383c88ec6a 368 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 225 363 6.4E-29 T 29-03-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding CB4_RS17015 d348df1e8da4bb10648e2f383c88ec6a 368 Pfam PF03445 Putative nucleotidyltransferase DUF294 58 183 4.3E-32 T 29-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 CB4_RS07855 754b624fe262bdf68730b5e9084a6e3c 131 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 5 128 3.0E-9 T 29-03-2018 CB4_RS13910 1c6c99ff0b1c5afcccb1463d0efc990b 303 Pfam PF05425 Copper resistance protein D 199 296 6.7E-10 T 29-03-2018 IPR008457 Copper resistance protein D GO:0016021 CB4_RS14075 93406f8ff60d7ceb8c0082df296b8284 149 SUPERFAMILY SSF53098 12 132 5.76E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS14075 93406f8ff60d7ceb8c0082df296b8284 149 Pfam PF01609 Transposase DDE domain 31 134 7.2E-10 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CB4_RS14075 93406f8ff60d7ceb8c0082df296b8284 149 Gene3D G3DSA:3.90.350.10 10 146 2.6E-6 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CB4_RS10715 1647335e39e45b33b94ae48760fef46e 277 SUPERFAMILY SSF53850 2 267 1.32E-76 T 29-03-2018 CB4_RS10715 1647335e39e45b33b94ae48760fef46e 277 Gene3D G3DSA:3.40.190.10 1 172 4.3E-79 T 29-03-2018 CB4_RS10715 1647335e39e45b33b94ae48760fef46e 277 Gene3D G3DSA:3.40.190.10 173 273 3.4E-13 T 29-03-2018 CB4_RS10715 1647335e39e45b33b94ae48760fef46e 277 Pfam PF02621 Menaquinone biosynthesis 1 262 3.6E-84 T 29-03-2018 IPR003773 Menaquinone biosynthesis enzyme CB4_RS10715 1647335e39e45b33b94ae48760fef46e 277 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 1 268 35.469 T 29-03-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 CB4_RS13165 f056dd8c2bb8e51d08c87c32e544c820 230 SUPERFAMILY SSF53335 3 181 2.59E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS13165 f056dd8c2bb8e51d08c87c32e544c820 230 Pfam PF08241 Methyltransferase domain 44 138 4.9E-31 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CB4_RS13165 f056dd8c2bb8e51d08c87c32e544c820 230 Gene3D G3DSA:3.40.50.150 2 225 2.9E-37 T 29-03-2018 CB4_RS05455 f05d3cbf2de9de27e1a1996e1c8b25e3 375 SUPERFAMILY SSF53756 1 372 1.63E-89 T 29-03-2018 CB4_RS05455 f05d3cbf2de9de27e1a1996e1c8b25e3 375 Gene3D G3DSA:3.40.50.2000 184 355 1.8E-47 T 29-03-2018 CB4_RS05455 f05d3cbf2de9de27e1a1996e1c8b25e3 375 Gene3D G3DSA:3.40.50.2000 1 183 9.5E-21 T 29-03-2018 CB4_RS05455 f05d3cbf2de9de27e1a1996e1c8b25e3 375 Pfam PF13439 Glycosyltransferase Family 4 15 175 2.1E-25 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CB4_RS05455 f05d3cbf2de9de27e1a1996e1c8b25e3 375 Pfam PF00534 Glycosyl transferases group 1 186 349 7.1E-38 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CB4_RS06670 42ada2a395c81a6caf35dfc7073b81dd 344 Gene3D G3DSA:1.10.10.10 1 84 1.3E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS06670 42ada2a395c81a6caf35dfc7073b81dd 344 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 1.1E-106 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CB4_RS06670 42ada2a395c81a6caf35dfc7073b81dd 344 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 1 72 8.2E-5 T 29-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 CB4_RS06670 42ada2a395c81a6caf35dfc7073b81dd 344 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 329 31.461 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CB4_RS06670 42ada2a395c81a6caf35dfc7073b81dd 344 Gene3D G3DSA:3.30.450.40 188 342 4.5E-42 T 29-03-2018 IPR029016 GAF domain-like CB4_RS06670 42ada2a395c81a6caf35dfc7073b81dd 344 SUPERFAMILY SSF55781 71 337 1.14E-62 T 29-03-2018 IPR029016 GAF domain-like CB4_RS06670 42ada2a395c81a6caf35dfc7073b81dd 344 Pfam PF01628 HrcA protein C terminal domain 104 322 7.6E-65 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CB4_RS06670 42ada2a395c81a6caf35dfc7073b81dd 344 SUPERFAMILY SSF46785 1 80 3.34E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS06670 42ada2a395c81a6caf35dfc7073b81dd 344 PIRSF PIRSF005485 1 340 4.6E-117 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CB4_RS02800 8407cdacec7832f418464eaedb162b34 121 Pfam PF00072 Response regulator receiver domain 6 116 3.2E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS02800 8407cdacec7832f418464eaedb162b34 121 SMART SM00448 4 115 9.0E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS02800 8407cdacec7832f418464eaedb162b34 121 Gene3D G3DSA:3.40.50.2300 1 120 1.6E-36 T 29-03-2018 CB4_RS02800 8407cdacec7832f418464eaedb162b34 121 SUPERFAMILY SSF52172 2 119 1.24E-39 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS11840 7a1168622505d3614255e11e7420a913 201 PIRSF PIRSF032620 4 197 1.2E-65 T 29-03-2018 IPR014571 Uncharacterised conserved protein UCP032620 CB4_RS11840 7a1168622505d3614255e11e7420a913 201 Pfam PF10137 Predicted nucleotide-binding protein containing TIR-like domain 58 175 9.8E-44 T 29-03-2018 IPR019302 Nucleotide-binding protein, predicted, TIR-like domain CB4_RS02335 67f447547a2d1a66f00500c778a971dd 448 Pfam PF02386 Cation transport protein 37 432 4.1E-59 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CB4_RS04830 3bef279e9360e8fb1f9901502218a6d0 187 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 1 185 32.6 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CB4_RS04830 3bef279e9360e8fb1f9901502218a6d0 187 PIRSF PIRSF001296 1 187 1.9E-70 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CB4_RS04830 3bef279e9360e8fb1f9901502218a6d0 187 Pfam PF02669 K+-transporting ATPase, c chain 5 182 3.4E-70 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CB4_RS04830 3bef279e9360e8fb1f9901502218a6d0 187 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 6 180 1.5E-55 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CB4_RS06860 e6fd4dda0909cb20e655322e53c305dc 108 SUPERFAMILY SSF69279 11 106 1.7E-5 T 29-03-2018 CB4_RS05945 37caa5606f1e53d3c89e534a60c5af36 275 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 5 275 39.363 T 29-03-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|MetaCyc: PWY-6987 CB4_RS05945 37caa5606f1e53d3c89e534a60c5af36 275 SUPERFAMILY SSF55681 9 246 2.65E-58 T 29-03-2018 CB4_RS05945 37caa5606f1e53d3c89e534a60c5af36 275 Gene3D G3DSA:3.30.930.10 6 266 6.8E-39 T 29-03-2018 CB4_RS05945 37caa5606f1e53d3c89e534a60c5af36 275 Pfam PF03099 Biotin/lipoate A/B protein ligase family 82 180 2.1E-8 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CB4_RS07605 9918f741e67bb6117f45a731c02365aa 106 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 5.4E-26 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 CB4_RS07605 9918f741e67bb6117f45a731c02365aa 106 PIRSF PIRSF031653 1 94 2.6E-27 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 CB4_RS15895 c1de18bd5cc9fecfcb108d12f6eec062 52 Pfam PF13076 Fur-regulated basic protein A 12 41 5.1E-8 T 29-03-2018 IPR025072 Fur-regulated basic protein A CB4_RS09325 276f772fc9ecd73c852535c383f5349a 99 SUPERFAMILY SSF55315 2 97 6.77E-27 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CB4_RS09325 276f772fc9ecd73c852535c383f5349a 99 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 3 93 3.2E-18 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CB4_RS09325 276f772fc9ecd73c852535c383f5349a 99 Gene3D G3DSA:3.30.1330.30 1 98 2.4E-23 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CB4_RS09620 0439fdb168fb927c5beeee02565a2c37 1651 Pfam PF01823 MAC/Perforin domain 182 240 4.2E-5 T 29-03-2018 IPR020864 Membrane attack complex component/perforin (MACPF) domain CB4_RS09620 0439fdb168fb927c5beeee02565a2c37 1651 ProSitePatterns PS00279 Membrane attack complex/perforin (MACPF) domain signature. 194 205 - T 29-03-2018 IPR020863 Membrane attack complex component/perforin domain, conserved site Reactome: R-HSA-166665|Reactome: R-HSA-977606 CB4_RS09620 0439fdb168fb927c5beeee02565a2c37 1651 Gene3D G3DSA:1.20.1000.10 263 723 2.0E-4 T 29-03-2018 CB4_RS07670 3a20c8abc735539247a862bfaa3626d7 274 ProDom PD123329 YQHG BH2818 5 271 2.0E-57 T 29-03-2018 IPR024562 Uncharacterised protein family YqhG CB4_RS07670 3a20c8abc735539247a862bfaa3626d7 274 Pfam PF11079 Bacterial protein YqhG of unknown function 6 271 4.0E-81 T 29-03-2018 IPR024562 Uncharacterised protein family YqhG CB4_RS04280 dbb8a0ab0b7bcbb08958c46014086f68 182 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 4 176 2.8E-53 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CB4_RS04280 dbb8a0ab0b7bcbb08958c46014086f68 182 SUPERFAMILY SSF52540 3 178 1.03E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS04280 dbb8a0ab0b7bcbb08958c46014086f68 182 Gene3D G3DSA:3.40.50.300 3 178 3.6E-55 T 29-03-2018 CB4_RS04280 dbb8a0ab0b7bcbb08958c46014086f68 182 PIRSF PIRSF006135 2 180 1.4E-52 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CB4_RS19650 97ee5175b64979ed5134a87fe17b6bb1 589 Pfam PF13034 Protein of unknown function (DUF3895) 511 583 7.9E-7 T 29-03-2018 IPR024995 Protein of unknown function DUF3895 CB4_RS19650 97ee5175b64979ed5134a87fe17b6bb1 589 Pfam PF06054 Competence protein CoiA-like family 1 391 1.7E-25 T 29-03-2018 IPR010330 Competence-induced protein CoiA-like CB4_RS19650 97ee5175b64979ed5134a87fe17b6bb1 589 Gene3D G3DSA:2.10.110.10 12 291 0.0034 T 29-03-2018 CB4_RS10020 ec988f2f80aa7af7739364cb5258f0dc 393 SUPERFAMILY SSF53067 7 192 2.53E-6 T 29-03-2018 CB4_RS10020 ec988f2f80aa7af7739364cb5258f0dc 393 Gene3D G3DSA:3.30.420.40 6 218 1.9E-24 T 29-03-2018 CB4_RS05555 f2960a003e17177ad60b510c4ac7457d 158 SUPERFAMILY SSF54637 14 150 7.47E-33 T 29-03-2018 IPR029069 HotDog domain CB4_RS05555 f2960a003e17177ad60b510c4ac7457d 158 Gene3D G3DSA:3.10.129.10 6 154 4.9E-34 T 29-03-2018 CB4_RS05555 f2960a003e17177ad60b510c4ac7457d 158 Pfam PF13279 Thioesterase-like superfamily 30 147 2.5E-13 T 29-03-2018 CB4_RS16365 5eef1f00c45bb11206c15834197cbd51 550 Pfam PF01642 Methylmalonyl-CoA mutase 34 545 3.1E-235 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CB4_RS16365 5eef1f00c45bb11206c15834197cbd51 550 Gene3D G3DSA:3.20.20.240 31 547 1.4E-230 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CB4_RS16365 5eef1f00c45bb11206c15834197cbd51 550 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 31 549 3.0E-248 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CB4_RS16365 5eef1f00c45bb11206c15834197cbd51 550 SUPERFAMILY SSF51703 9 547 2.09E-220 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CB4_RS08805 af6d0b79829d197426869f8e0b6c896b 194 SUPERFAMILY SSF161266 23 159 6.28E-8 T 29-03-2018 CB4_RS08805 af6d0b79829d197426869f8e0b6c896b 194 Pfam PF07352 Bacteriophage Mu Gam like protein 30 192 3.3E-19 T 29-03-2018 IPR009951 Host-nuclease inhibitor protein Gam GO:0003690|GO:0042262 CB4_RS12060 daaad2abfb1dededad18090bee4232d3 94 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CB4_RS12060 daaad2abfb1dededad18090bee4232d3 94 Gene3D G3DSA:3.10.20.30 2 93 8.8E-21 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS12060 daaad2abfb1dededad18090bee4232d3 94 SUPERFAMILY SSF54292 3 90 1.27E-23 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CB4_RS12060 daaad2abfb1dededad18090bee4232d3 94 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 81 6.1E-14 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CB4_RS00040 6488f24c727e7045a924fa54ed08827d 285 Gene3D G3DSA:3.30.240.20 82 151 1.2E-23 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CB4_RS00040 6488f24c727e7045a924fa54ed08827d 285 Gene3D G3DSA:3.30.240.20 167 226 4.4E-11 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CB4_RS00040 6488f24c727e7045a924fa54ed08827d 285 Pfam PF04239 Protein of unknown function (DUF421) 89 204 6.1E-31 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CB4_RS00040 6488f24c727e7045a924fa54ed08827d 285 Pfam PF07870 Protein of unknown function (DUF1657) 237 284 4.7E-17 T 29-03-2018 IPR012452 Protein of unknown function DUF1657 CB4_RS13410 5c3f581c7b7123e6bfb0b071acc906b2 168 SUPERFAMILY SSF57850 12 65 9.71E-6 T 29-03-2018 CB4_RS13410 5c3f581c7b7123e6bfb0b071acc906b2 168 Gene3D G3DSA:3.30.40.10 9 72 1.3E-8 T 29-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type CB4_RS18230 e94e9ff31b1d9165c1c2cc145b4c76a6 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 8.1E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS18230 e94e9ff31b1d9165c1c2cc145b4c76a6 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 8.1E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS18230 e94e9ff31b1d9165c1c2cc145b4c76a6 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 8.1E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS18230 e94e9ff31b1d9165c1c2cc145b4c76a6 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS18230 e94e9ff31b1d9165c1c2cc145b4c76a6 119 SUPERFAMILY SSF74731 2 116 2.75E-48 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS18230 e94e9ff31b1d9165c1c2cc145b4c76a6 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.8E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS18230 e94e9ff31b1d9165c1c2cc145b4c76a6 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.687 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS18230 e94e9ff31b1d9165c1c2cc145b4c76a6 119 Gene3D G3DSA:1.10.1900.20 55 116 5.1E-29 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS18230 e94e9ff31b1d9165c1c2cc145b4c76a6 119 Pfam PF00453 Ribosomal protein L20 3 109 1.6E-47 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS18230 e94e9ff31b1d9165c1c2cc145b4c76a6 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 8.0E-20 T 29-03-2018 CB4_RS15005 9e79b7d266d235e40a1f1b85a5f3ad44 116 SUPERFAMILY SSF101386 6 108 3.05E-29 T 29-03-2018 CB4_RS15005 9e79b7d266d235e40a1f1b85a5f3ad44 116 Gene3D G3DSA:1.10.3420.10 1 113 3.0E-28 T 29-03-2018 CB4_RS15005 9e79b7d266d235e40a1f1b85a5f3ad44 116 PIRSF PIRSF029904 5 115 8.9E-52 T 29-03-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD CB4_RS15005 9e79b7d266d235e40a1f1b85a5f3ad44 116 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 29 108 4.2E-20 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CB4_RS02810 04fc1f2387ed91d34bd3a1e5f545538f 215 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 5.2E-101 T 29-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CB4_RS02810 04fc1f2387ed91d34bd3a1e5f545538f 215 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CB4_RS02810 04fc1f2387ed91d34bd3a1e5f545538f 215 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 210 6.9E-56 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CB4_RS02810 04fc1f2387ed91d34bd3a1e5f545538f 215 Hamap MF_00494 Probable transaldolase [tal]. 1 214 48.439 T 29-03-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CB4_RS02810 04fc1f2387ed91d34bd3a1e5f545538f 215 SUPERFAMILY SSF51569 1 212 1.04E-78 T 29-03-2018 CB4_RS02810 04fc1f2387ed91d34bd3a1e5f545538f 215 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CB4_RS02810 04fc1f2387ed91d34bd3a1e5f545538f 215 Gene3D G3DSA:3.20.20.70 1 215 1.2E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS02895 57106fd0ffa75820352f920c925f7d34 429 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 229 381 9.3E-37 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02895 57106fd0ffa75820352f920c925f7d34 429 Pfam PF00672 HAMP domain 71 121 4.3E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS02895 57106fd0ffa75820352f920c925f7d34 429 Gene3D G3DSA:1.10.287.950 79 180 1.0E-8 T 29-03-2018 CB4_RS02895 57106fd0ffa75820352f920c925f7d34 429 SMART SM00283 153 428 6.2E-61 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02895 57106fd0ffa75820352f920c925f7d34 429 SUPERFAMILY SSF58104 159 427 1.57E-64 T 29-03-2018 CB4_RS02895 57106fd0ffa75820352f920c925f7d34 429 SUPERFAMILY SSF58104 91 126 1.57E-64 T 29-03-2018 CB4_RS02895 57106fd0ffa75820352f920c925f7d34 429 SMART SM00304 71 124 6.6E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS02895 57106fd0ffa75820352f920c925f7d34 429 Gene3D G3DSA:1.10.287.950 181 429 7.4E-47 T 29-03-2018 CB4_RS08530 660f91eb45a0b7939a200786689a1734 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 17.961 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS08530 660f91eb45a0b7939a200786689a1734 62 SUPERFAMILY SSF143800 1 61 1.51E-22 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08530 660f91eb45a0b7939a200786689a1734 62 Gene3D G3DSA:2.30.170.40 2 60 5.7E-19 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08530 660f91eb45a0b7939a200786689a1734 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 4.6E-22 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CB4_RS08530 660f91eb45a0b7939a200786689a1734 62 Pfam PF00830 Ribosomal L28 family 3 57 7.1E-20 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00170 4d9295f4a57578da80bdeb7a18f5bc99 277 Gene3D G3DSA:1.10.3470.10 2 277 3.0E-30 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS00170 4d9295f4a57578da80bdeb7a18f5bc99 277 SUPERFAMILY SSF81345 4 269 4.58E-36 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CB4_RS00170 4d9295f4a57578da80bdeb7a18f5bc99 277 Pfam PF00950 ABC 3 transport family 8 270 3.9E-68 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CB4_RS03995 b2091fea05ec670cb1ff22c24fac85a0 327 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 297 5.4E-66 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CB4_RS03995 b2091fea05ec670cb1ff22c24fac85a0 327 SMART SM00797 23 316 9.9E-70 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CB4_RS03995 b2091fea05ec670cb1ff22c24fac85a0 327 SUPERFAMILY SSF50891 196 304 8.34E-6 T 29-03-2018 IPR029000 Cyclophilin-like domain CB4_RS12015 34aa76faece1f7773609a6eb06ec0c21 463 SUPERFAMILY SSF53474 262 435 1.94E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS12015 34aa76faece1f7773609a6eb06ec0c21 463 SUPERFAMILY SSF53474 163 227 1.94E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS12015 34aa76faece1f7773609a6eb06ec0c21 463 Gene3D G3DSA:3.40.50.1820 52 436 6.0E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS03370 adfbbd1b1fc1d330b2b55473d9304b6a 85 SUPERFAMILY SSF89447 6 49 6.63E-5 T 29-03-2018 CB4_RS03370 adfbbd1b1fc1d330b2b55473d9304b6a 85 Gene3D G3DSA:2.10.260.10 1 83 1.1E-5 T 29-03-2018 CB4_RS14225 7d3214306bc0b25bde534e736fcd3d4c 353 Pfam PF10776 Protein of unknown function (DUF2600) 10 340 6.3E-137 T 29-03-2018 IPR019712 Protein of unknown function DUF2600 KEGG: 00909+4.2.3.13|MetaCyc: PWY-5773|MetaCyc: PWY-5828 CB4_RS14225 7d3214306bc0b25bde534e736fcd3d4c 353 SUPERFAMILY SSF48576 10 266 3.02E-5 T 29-03-2018 IPR008949 Isoprenoid synthase domain CB4_RS07700 94521100b43622f744bbd612aa5c1d0c 450 Gene3D G3DSA:3.90.1150.10 337 449 5.7E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS07700 94521100b43622f744bbd612aa5c1d0c 450 Pfam PF02347 Glycine cleavage system P-protein 4 442 2.3E-154 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CB4_RS07700 94521100b43622f744bbd612aa5c1d0c 450 Gene3D G3DSA:3.40.640.10 84 336 1.6E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS07700 94521100b43622f744bbd612aa5c1d0c 450 PIRSF PIRSF006815 3 448 8.7E-194 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CB4_RS07700 94521100b43622f744bbd612aa5c1d0c 450 SUPERFAMILY SSF53383 3 445 1.61E-127 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS07700 94521100b43622f744bbd612aa5c1d0c 450 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 447 49.367 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CB4_RS13245 74fe09195b07d33e2cd63ca8175e1723 271 Pfam PF11155 Domain of unknown function (DUF2935) 139 255 3.9E-33 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CB4_RS13245 74fe09195b07d33e2cd63ca8175e1723 271 Pfam PF11155 Domain of unknown function (DUF2935) 10 124 8.8E-30 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CB4_RS13245 74fe09195b07d33e2cd63ca8175e1723 271 SUPERFAMILY SSF158430 134 259 3.66E-40 T 29-03-2018 CB4_RS13245 74fe09195b07d33e2cd63ca8175e1723 271 SUPERFAMILY SSF158430 3 130 1.83E-38 T 29-03-2018 CB4_RS13650 69f57420ca5fc946f5aef88d5be08765 127 Pfam PF12840 Helix-turn-helix domain 28 86 1.5E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13650 69f57420ca5fc946f5aef88d5be08765 127 Gene3D G3DSA:1.10.10.10 19 127 4.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13650 69f57420ca5fc946f5aef88d5be08765 127 SMART SM00418 28 106 6.5E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13650 69f57420ca5fc946f5aef88d5be08765 127 SUPERFAMILY SSF46785 28 118 4.45E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13650 69f57420ca5fc946f5aef88d5be08765 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 45 2.0E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13650 69f57420ca5fc946f5aef88d5be08765 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 2.0E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13650 69f57420ca5fc946f5aef88d5be08765 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 77 92 2.0E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS18070 ed07dc5ac19d126d3156fc1132a45053 280 Gene3D G3DSA:3.40.190.10 40 135 6.0E-22 T 29-03-2018 CB4_RS18070 ed07dc5ac19d126d3156fc1132a45053 280 Gene3D G3DSA:3.40.190.10 136 278 3.2E-42 T 29-03-2018 CB4_RS18070 ed07dc5ac19d126d3156fc1132a45053 280 Pfam PF03180 NLPA lipoprotein 42 276 6.5E-80 T 29-03-2018 IPR004872 Lipoprotein NlpA family CB4_RS18070 ed07dc5ac19d126d3156fc1132a45053 280 SUPERFAMILY SSF53850 41 277 7.56E-70 T 29-03-2018 CB4_RS18070 ed07dc5ac19d126d3156fc1132a45053 280 PIRSF PIRSF002854 1 277 4.2E-83 T 29-03-2018 IPR004872 Lipoprotein NlpA family CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 Gene3D G3DSA:3.40.800.20 2 352 1.7E-96 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 PRINTS PR01270 Histone deacetylase superfamily signature 249 259 4.5E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 PRINTS PR01270 Histone deacetylase superfamily signature 163 178 4.5E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 PRINTS PR01270 Histone deacetylase superfamily signature 130 153 4.5E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 107 120 1.9E-30 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 86 100 1.9E-30 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 335 351 1.9E-30 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 352 371 1.9E-30 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 1.9E-30 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 274 290 1.9E-30 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 Pfam PF00850 Histone deacetylase domain 22 318 5.5E-77 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CB4_RS17315 0f1aeff269fc25854de600aa6675e0d5 385 SUPERFAMILY SSF52768 3 357 3.12E-106 T 29-03-2018 CB4_RS07475 8c661692ff808d7127cef7e56c3bf8fa 267 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 260 8.1E-108 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CB4_RS07475 8c661692ff808d7127cef7e56c3bf8fa 267 Pfam PF08543 Phosphomethylpyrimidine kinase 13 258 3.9E-102 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CB4_RS07475 8c661692ff808d7127cef7e56c3bf8fa 267 SUPERFAMILY SSF53613 4 262 8.26E-89 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS07475 8c661692ff808d7127cef7e56c3bf8fa 267 Gene3D G3DSA:3.40.1190.20 2 267 1.0E-70 T 29-03-2018 IPR029056 Ribokinase-like CB4_RS19570 233e0a65360339145b53cf4e06eb2699 500 Pfam PF05621 Bacterial TniB protein 133 368 2.9E-18 T 29-03-2018 IPR008868 Bacterial TniB CB4_RS19570 233e0a65360339145b53cf4e06eb2699 500 SUPERFAMILY SSF52540 117 380 4.07E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19570 233e0a65360339145b53cf4e06eb2699 500 Gene3D G3DSA:3.40.50.300 117 389 7.6E-7 T 29-03-2018 CB4_RS10170 b57f6a6ecb2328ae40cf613e73bace0c 106 SUPERFAMILY SSF103481 4 104 1.83E-17 T 29-03-2018 CB4_RS10170 b57f6a6ecb2328ae40cf613e73bace0c 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.4E-26 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CB4_RS07560 448d18e4823d82b16c5a8b31cf98236a 166 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 4 165 2.0E-36 T 29-03-2018 IPR020229 Uncharacterised protein YlaL CB4_RS07560 448d18e4823d82b16c5a8b31cf98236a 166 Gene3D G3DSA:3.90.420.10 60 165 1.4E-5 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CB4_RS07110 add4c93f5d934ca103f6de0d2299cca2 134 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 130 2.5E-45 T 29-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CB4_RS07110 add4c93f5d934ca103f6de0d2299cca2 134 Gene3D G3DSA:3.40.140.10 2 133 1.4E-48 T 29-03-2018 CB4_RS07110 add4c93f5d934ca103f6de0d2299cca2 134 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 103 3.0E-17 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CB4_RS07110 add4c93f5d934ca103f6de0d2299cca2 134 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CB4_RS07110 add4c93f5d934ca103f6de0d2299cca2 134 SUPERFAMILY SSF53927 4 130 1.07E-44 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CB4_RS12775 d963ba0112bf0dd5a2aaac3946fa4187 417 Pfam PF07690 Major Facilitator Superfamily 5 332 1.8E-34 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS12775 d963ba0112bf0dd5a2aaac3946fa4187 417 SUPERFAMILY SSF103473 2 401 8.11E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS12775 d963ba0112bf0dd5a2aaac3946fa4187 417 Gene3D G3DSA:1.20.1250.20 1 193 6.9E-26 T 29-03-2018 CB4_RS12775 d963ba0112bf0dd5a2aaac3946fa4187 417 Gene3D G3DSA:1.20.1250.20 214 411 2.5E-23 T 29-03-2018 CB4_RS09830 d2ae877fa48ebd46e5396c4cbc07f7a0 325 SUPERFAMILY SSF50891 187 302 6.07E-9 T 29-03-2018 IPR029000 Cyclophilin-like domain CB4_RS09830 d2ae877fa48ebd46e5396c4cbc07f7a0 325 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 295 1.0E-92 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CB4_RS09830 d2ae877fa48ebd46e5396c4cbc07f7a0 325 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 318 4.6E-95 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CB4_RS09830 d2ae877fa48ebd46e5396c4cbc07f7a0 325 SMART SM00797 24 312 3.6E-141 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CB4_RS10305 fd38be91043760b7f617a8a072e6106e 199 PIRSF PIRSF037778 1 199 2.5E-46 T 29-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CB4_RS10305 fd38be91043760b7f617a8a072e6106e 199 Pfam PF12822 ECF transporter, substrate-specific component 6 187 4.6E-25 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CB4_RS11575 f22104c1a7c29734caa0aaa49be77a29 191 Gene3D G3DSA:2.60.40.1080 23 168 1.8E-5 T 29-03-2018 CB4_RS11065 591b088ee6839ae6f3f1bae3f1ca43da 554 Gene3D G3DSA:2.140.10.10 429 553 1.1E-11 T 29-03-2018 CB4_RS11065 591b088ee6839ae6f3f1bae3f1ca43da 554 Gene3D G3DSA:2.140.10.10 100 428 1.0E-23 T 29-03-2018 CB4_RS11065 591b088ee6839ae6f3f1bae3f1ca43da 554 SUPERFAMILY SSF50998 110 211 6.39E-18 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CB4_RS11065 591b088ee6839ae6f3f1bae3f1ca43da 554 SUPERFAMILY SSF50998 332 549 6.39E-18 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CB4_RS11065 591b088ee6839ae6f3f1bae3f1ca43da 554 SUPERFAMILY SSF50998 265 300 6.39E-18 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CB4_RS19730 8a3c58d815cf4c50c5e04625f30b8684 319 SUPERFAMILY SSF144083 250 313 1.05E-23 T 29-03-2018 CB4_RS19730 8a3c58d815cf4c50c5e04625f30b8684 319 Gene3D G3DSA:1.20.58.340 125 246 2.9E-25 T 29-03-2018 CB4_RS19730 8a3c58d815cf4c50c5e04625f30b8684 319 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 14 315 6.4E-94 T 29-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CB4_RS19730 8a3c58d815cf4c50c5e04625f30b8684 319 Gene3D G3DSA:1.20.58.340 247 315 9.4E-27 T 29-03-2018 CB4_RS19730 8a3c58d815cf4c50c5e04625f30b8684 319 Pfam PF01544 CorA-like Mg2+ transporter protein 28 311 4.2E-78 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CB4_RS19730 8a3c58d815cf4c50c5e04625f30b8684 319 Gene3D G3DSA:3.30.460.20 1 122 5.3E-30 T 29-03-2018 CB4_RS19730 8a3c58d815cf4c50c5e04625f30b8684 319 SUPERFAMILY SSF143865 25 248 3.79E-59 T 29-03-2018 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 Pfam PF13365 Trypsin-like peptidase domain 114 262 8.8E-29 T 29-03-2018 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 Gene3D G3DSA:2.40.10.10 190 299 2.0E-33 T 29-03-2018 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 Gene3D G3DSA:2.30.42.10 300 403 3.5E-23 T 29-03-2018 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 SMART SM00228 300 388 1.0E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 SUPERFAMILY SSF50494 79 295 4.28E-54 T 29-03-2018 IPR009003 Peptidase S1, PA clan CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 Pfam PF13180 PDZ domain 319 397 5.2E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 SUPERFAMILY SSF50156 283 396 5.78E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 PRINTS PR00834 HtrA/DegQ protease family signature 255 272 3.4E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 PRINTS PR00834 HtrA/DegQ protease family signature 189 213 3.4E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 PRINTS PR00834 HtrA/DegQ protease family signature 148 168 3.4E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 PRINTS PR00834 HtrA/DegQ protease family signature 233 250 3.4E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 PRINTS PR00834 HtrA/DegQ protease family signature 126 138 3.4E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 PRINTS PR00834 HtrA/DegQ protease family signature 346 358 3.4E-37 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CB4_RS02070 1c329d3387ca8e4425df85c892d6d88b 403 Gene3D G3DSA:2.40.10.10 74 189 6.1E-28 T 29-03-2018 CB4_RS16670 27dd53016c5e25bf0f4632accfc41cb0 371 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 73 330 5.2E-50 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CB4_RS16670 27dd53016c5e25bf0f4632accfc41cb0 371 Gene3D G3DSA:3.40.50.2300 187 360 2.4E-22 T 29-03-2018 CB4_RS16670 27dd53016c5e25bf0f4632accfc41cb0 371 Gene3D G3DSA:3.40.50.2300 70 186 3.0E-25 T 29-03-2018 CB4_RS16670 27dd53016c5e25bf0f4632accfc41cb0 371 SUPERFAMILY SSF53822 73 298 2.59E-8 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS02915 482d686bbed838238343b36a06ec633b 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 1.3E-74 T 29-03-2018 CB4_RS02915 482d686bbed838238343b36a06ec633b 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 2.8E-91 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CB4_RS02915 482d686bbed838238343b36a06ec633b 209 SUPERFAMILY SSF53271 4 207 1.31E-71 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CB4_RS02915 482d686bbed838238343b36a06ec633b 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.624 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CB4_RS02915 482d686bbed838238343b36a06ec633b 209 Gene3D G3DSA:3.40.50.2020 2 207 1.2E-64 T 29-03-2018 CB4_RS13175 54fcefd3ff836e3550a1bd09630727fb 527 Gene3D G3DSA:3.40.50.970 341 527 1.3E-28 T 29-03-2018 CB4_RS13175 54fcefd3ff836e3550a1bd09630727fb 527 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 379 525 1.3E-30 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CB4_RS13175 54fcefd3ff836e3550a1bd09630727fb 527 Gene3D G3DSA:3.40.50.970 2 184 1.1E-54 T 29-03-2018 CB4_RS13175 54fcefd3ff836e3550a1bd09630727fb 527 SUPERFAMILY SSF52467 160 342 1.0E-35 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CB4_RS13175 54fcefd3ff836e3550a1bd09630727fb 527 SUPERFAMILY SSF52518 4 180 4.17E-53 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS13175 54fcefd3ff836e3550a1bd09630727fb 527 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 416 435 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CB4_RS13175 54fcefd3ff836e3550a1bd09630727fb 527 Gene3D G3DSA:3.40.50.1220 185 340 5.2E-34 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CB4_RS13175 54fcefd3ff836e3550a1bd09630727fb 527 SUPERFAMILY SSF52518 359 527 1.09E-42 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS13175 54fcefd3ff836e3550a1bd09630727fb 527 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 2.1E-56 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CB4_RS13175 54fcefd3ff836e3550a1bd09630727fb 527 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 189 323 3.4E-29 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CB4_RS17310 0222c071f66be94508d83a793d92b42b 216 Pfam PF01842 ACT domain 142 201 2.1E-6 T 29-03-2018 IPR002912 ACT domain CB4_RS17310 0222c071f66be94508d83a793d92b42b 216 Gene3D G3DSA:3.30.70.260 153 207 1.1E-9 T 29-03-2018 CB4_RS17310 0222c071f66be94508d83a793d92b42b 216 Gene3D G3DSA:3.10.580.10 74 152 3.8E-9 T 29-03-2018 CB4_RS17310 0222c071f66be94508d83a793d92b42b 216 SUPERFAMILY SSF55021 141 204 9.92E-9 T 29-03-2018 CB4_RS17310 0222c071f66be94508d83a793d92b42b 216 SMART SM00116 10 57 9.2E-11 T 29-03-2018 IPR000644 CBS domain CB4_RS17310 0222c071f66be94508d83a793d92b42b 216 SMART SM00116 82 130 1.0E-11 T 29-03-2018 IPR000644 CBS domain CB4_RS17310 0222c071f66be94508d83a793d92b42b 216 Gene3D G3DSA:3.10.580.10 1 73 3.9E-16 T 29-03-2018 CB4_RS17310 0222c071f66be94508d83a793d92b42b 216 SUPERFAMILY SSF54631 1 133 3.17E-31 T 29-03-2018 CB4_RS17310 0222c071f66be94508d83a793d92b42b 216 Pfam PF00571 CBS domain 75 129 1.1E-11 T 29-03-2018 IPR000644 CBS domain CB4_RS17310 0222c071f66be94508d83a793d92b42b 216 Pfam PF00571 CBS domain 3 55 1.0E-13 T 29-03-2018 IPR000644 CBS domain CB4_RS04895 8cacd7c83ed83cce4eb764b9dc31d1c5 111 Gene3D G3DSA:2.40.440.10 1 110 1.8E-32 T 29-03-2018 CB4_RS04895 8cacd7c83ed83cce4eb764b9dc31d1c5 111 SUPERFAMILY SSF141523 3 109 9.68E-37 T 29-03-2018 CB4_RS04895 8cacd7c83ed83cce4eb764b9dc31d1c5 111 Pfam PF03734 L,D-transpeptidase catalytic domain 3 108 1.9E-21 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CB4_RS00605 92367acd02b0582a92b5ac6f36baee89 600 Pfam PF13522 Glutamine amidotransferase domain 60 191 1.5E-21 T 29-03-2018 CB4_RS00605 92367acd02b0582a92b5ac6f36baee89 600 Gene3D G3DSA:3.40.50.10490 452 598 1.2E-44 T 29-03-2018 CB4_RS00605 92367acd02b0582a92b5ac6f36baee89 600 Gene3D G3DSA:3.40.50.10490 239 451 2.3E-56 T 29-03-2018 CB4_RS00605 92367acd02b0582a92b5ac6f36baee89 600 SUPERFAMILY SSF53697 244 600 2.5E-96 T 29-03-2018 CB4_RS00605 92367acd02b0582a92b5ac6f36baee89 600 Pfam PF01380 SIS domain 289 413 1.2E-32 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CB4_RS00605 92367acd02b0582a92b5ac6f36baee89 600 Pfam PF01380 SIS domain 461 582 8.5E-18 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CB4_RS00605 92367acd02b0582a92b5ac6f36baee89 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 39.329 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CB4_RS00605 92367acd02b0582a92b5ac6f36baee89 600 Gene3D G3DSA:3.60.20.10 2 238 8.5E-65 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS00605 92367acd02b0582a92b5ac6f36baee89 600 SUPERFAMILY SSF56235 2 235 2.57E-66 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CB4_RS00605 92367acd02b0582a92b5ac6f36baee89 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 1.4E-233 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CB4_RS09735 41245d3606393ac15043a5686f89f2ed 353 SUPERFAMILY SSF51395 3 345 4.51E-112 T 29-03-2018 CB4_RS09735 41245d3606393ac15043a5686f89f2ed 353 Gene3D G3DSA:3.20.20.70 1 351 5.5E-115 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS09735 41245d3606393ac15043a5686f89f2ed 353 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 339 9.7E-88 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CB4_RS02195 e96a83b8ebda547c14dd16122be08103 123 Pfam PF03788 LrgA family 19 110 1.9E-27 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CB4_RS12130 5ae9bb57416cc18581944ef6f27c7295 340 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 324 8.7E-74 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CB4_RS12130 5ae9bb57416cc18581944ef6f27c7295 340 Gene3D G3DSA:3.20.20.70 1 338 4.9E-112 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS12130 5ae9bb57416cc18581944ef6f27c7295 340 SUPERFAMILY SSF51395 1 335 7.63E-106 T 29-03-2018 CB4_RS01270 500062dc4e017993efd1d7a38aabe71a 151 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 149 3.3E-54 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CB4_RS01270 500062dc4e017993efd1d7a38aabe71a 151 PIRSF PIRSF010607 1 151 3.8E-57 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CB4_RS16880 5df296621508efba775b6f1902aef2b0 314 Gene3D G3DSA:1.10.3470.10 2 280 3.0E-32 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS16880 5df296621508efba775b6f1902aef2b0 314 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 275 3.7E-30 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS12430 21be6ba7a3f6844677d86a16ecb492e9 114 Gene3D G3DSA:3.40.30.10 1 114 1.1E-24 T 29-03-2018 CB4_RS12430 21be6ba7a3f6844677d86a16ecb492e9 114 SUPERFAMILY SSF52833 2 105 6.82E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS12430 21be6ba7a3f6844677d86a16ecb492e9 114 Pfam PF00085 Thioredoxin 5 104 5.5E-18 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CB4_RS11675 0914f61d33c8e591e0d300acefb144eb 185 Pfam PF06378 Protein of unknown function (DUF1071) 8 137 7.5E-51 T 29-03-2018 IPR009425 Single-strand annealing protein SAK3 CB4_RS09555 12d16d662a178183124bca6f6e3c2337 43 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 1 37 1.8E-6 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CB4_RS16810 4e571baaa618bfa368bb5ff5164a34bf 216 Gene3D G3DSA:3.40.1080.10 3 214 3.6E-74 T 29-03-2018 CB4_RS16810 4e571baaa618bfa368bb5ff5164a34bf 216 SUPERFAMILY SSF100950 4 211 4.19E-75 T 29-03-2018 CB4_RS16810 4e571baaa618bfa368bb5ff5164a34bf 216 SMART SM00882 6 202 7.3E-82 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CB4_RS16810 4e571baaa618bfa368bb5ff5164a34bf 216 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 208 9.3E-102 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CB4_RS16810 4e571baaa618bfa368bb5ff5164a34bf 216 Pfam PF01144 Coenzyme A transferase 6 200 8.9E-45 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CB4_RS16810 4e571baaa618bfa368bb5ff5164a34bf 216 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 29-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CB4_RS14030 b641b508f17197e77f8ec2c645938b63 275 SUPERFAMILY SSF53474 5 263 2.32E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS14030 b641b508f17197e77f8ec2c645938b63 275 Pfam PF12146 Serine aminopeptidase, S33 35 145 3.6E-14 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CB4_RS14030 b641b508f17197e77f8ec2c645938b63 275 Gene3D G3DSA:3.40.50.1820 3 267 6.7E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 109 123 3.2E-20 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 155 168 3.2E-20 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 3.2E-20 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 3 392 2.5E-85 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 Gene3D G3DSA:3.90.120.10 191 380 2.1E-19 T 29-03-2018 CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 70 82 - T 29-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 SUPERFAMILY SSF53335 1 215 5.34E-86 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 SUPERFAMILY SSF53335 272 392 5.34E-86 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 391 4.5E-87 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 374 392 - T 29-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CB4_RS11920 f6eef007aeaa2c9c1b2660093bdad10e 392 Gene3D G3DSA:3.40.50.150 1 190 2.0E-62 T 29-03-2018 CB4_RS03805 ea639ba3dd6ba3b1ea2fd1767dcb104a 320 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 10 315 5.0E-117 T 29-03-2018 IPR010119 Gluconeogenesis factor CB4_RS03805 ea639ba3dd6ba3b1ea2fd1767dcb104a 320 Hamap MF_00973 Gluconeogenesis factor. 6 318 35.638 T 29-03-2018 IPR010119 Gluconeogenesis factor CB4_RS03805 ea639ba3dd6ba3b1ea2fd1767dcb104a 320 Pfam PF01933 Uncharacterised protein family UPF0052 10 294 1.6E-103 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CB4_RS03805 ea639ba3dd6ba3b1ea2fd1767dcb104a 320 Gene3D G3DSA:3.40.50.10680 88 318 9.3E-57 T 29-03-2018 CB4_RS03805 ea639ba3dd6ba3b1ea2fd1767dcb104a 320 SUPERFAMILY SSF142338 7 313 6.54E-101 T 29-03-2018 CB4_RS07780 03213521eba2ca376474a26e6467cef9 120 SUPERFAMILY SSF53850 11 107 3.37E-11 T 29-03-2018 CB4_RS07780 03213521eba2ca376474a26e6467cef9 120 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 110 9.7E-11 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CB4_RS07780 03213521eba2ca376474a26e6467cef9 120 Gene3D G3DSA:3.40.190.10 38 117 9.3E-11 T 29-03-2018 CB4_RS03105 b319af187770466e319011e25e7f1773 50 Pfam PF11772 DNA-directed RNA polymerase subunit beta 5 48 1.2E-12 T 29-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA CB4_RS10185 1e3f2ce415cb90e136fe6f055a6af0da 587 Gene3D G3DSA:2.60.40.10 438 525 0.21 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS10185 1e3f2ce415cb90e136fe6f055a6af0da 587 Gene3D G3DSA:2.60.40.10 26 158 1.4E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS01575 425631e9b86cc78ec1f468430c60612b 266 Pfam PF04468 PSP1 C-terminal conserved region 61 146 1.1E-30 T 29-03-2018 IPR007557 PSP1, C-terminal CB4_RS08570 636d83d6df75db3d58deb51cb16354ce 414 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 13 353 1.1E-92 T 29-03-2018 IPR014226 Sporulation integral membrane protein YlbJ CB4_RS09545 ffa6285c9f30e1012d84cf62a3ce0548 113 Pfam PF09858 Predicted membrane protein (DUF2085) 10 93 2.3E-32 T 29-03-2018 IPR019206 Protein of unknown function DUF2085, transmembrane CB4_RS19065 8c4b3e2c3ce28a32a403675576d61741 142 Pfam PF01475 Ferric uptake regulator family 14 132 6.1E-37 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CB4_RS19065 8c4b3e2c3ce28a32a403675576d61741 142 Gene3D G3DSA:1.10.10.10 10 92 5.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19065 8c4b3e2c3ce28a32a403675576d61741 142 SUPERFAMILY SSF46785 8 136 1.74E-38 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12835 89b60ab10335132e416e78c6f0997193 103 SUPERFAMILY SSF46785 5 101 2.07E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12835 89b60ab10335132e416e78c6f0997193 103 Gene3D G3DSA:1.10.10.10 2 99 2.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12835 89b60ab10335132e416e78c6f0997193 103 SMART SM00418 5 101 3.2E-6 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS12835 89b60ab10335132e416e78c6f0997193 103 Pfam PF01022 Bacterial regulatory protein, arsR family 46 76 1.2E-4 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS11905 07647d1876837e7e465ed67f7d696ffe 55 Gene3D G3DSA:1.10.287.310 2 55 5.6E-4 T 29-03-2018 CB4_RS11905 07647d1876837e7e465ed67f7d696ffe 55 SUPERFAMILY SSF140500 3 52 1.19E-13 T 29-03-2018 CB4_RS11905 07647d1876837e7e465ed67f7d696ffe 55 Pfam PF09388 Spo0E like sporulation regulatory protein 7 48 1.9E-18 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CB4_RS08220 1fe594549639ae9ba9cc9d79b82a3a3e 125 Hamap MF_00910 Cell division protein FtsL [ftsL]. 37 119 12.145 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CB4_RS08220 1fe594549639ae9ba9cc9d79b82a3a3e 125 Pfam PF04977 Septum formation initiator 46 117 5.7E-8 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CB4_RS10730 2b2a4ad0ea4de3895bbc33050a500490 148 PRINTS PR01438 Universal stress protein signature 126 148 1.5E-22 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS10730 2b2a4ad0ea4de3895bbc33050a500490 148 PRINTS PR01438 Universal stress protein signature 108 120 1.5E-22 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS10730 2b2a4ad0ea4de3895bbc33050a500490 148 PRINTS PR01438 Universal stress protein signature 2 20 1.5E-22 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS10730 2b2a4ad0ea4de3895bbc33050a500490 148 Gene3D G3DSA:3.40.50.620 1 148 2.2E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS10730 2b2a4ad0ea4de3895bbc33050a500490 148 Pfam PF00582 Universal stress protein family 1 148 7.3E-33 T 29-03-2018 IPR006016 UspA GO:0006950 CB4_RS10730 2b2a4ad0ea4de3895bbc33050a500490 148 SUPERFAMILY SSF52402 2 148 6.28E-38 T 29-03-2018 CB4_RS10730 2b2a4ad0ea4de3895bbc33050a500490 148 PIRSF PIRSF006276 1 148 6.5E-17 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS08595 c394d43a33438aaad1bbe6e8cd7d8e1b 58 Pfam PF01783 Ribosomal L32p protein family 2 56 4.0E-28 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08595 c394d43a33438aaad1bbe6e8cd7d8e1b 58 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 1.0E-29 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08595 c394d43a33438aaad1bbe6e8cd7d8e1b 58 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 21.02 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS08595 c394d43a33438aaad1bbe6e8cd7d8e1b 58 SUPERFAMILY SSF57829 1 55 1.71E-23 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CB4_RS11415 febc67e866faa798f710f57adbc5a689 197 Pfam PF13814 Replication-relaxation 76 160 3.6E-6 T 29-03-2018 IPR025855 Plasmid replication-relaxation CB4_RS11415 febc67e866faa798f710f57adbc5a689 197 Gene3D G3DSA:1.10.10.10 1 68 0.0014 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04790 c5bd7d5935eff3798465b156c368a338 464 Pfam PF02511 Thymidylate synthase complementing protein 324 445 5.2E-10 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CB4_RS04790 c5bd7d5935eff3798465b156c368a338 464 Pfam PF02511 Thymidylate synthase complementing protein 68 243 1.1E-21 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CB4_RS04790 c5bd7d5935eff3798465b156c368a338 464 SUPERFAMILY SSF69796 66 251 1.83E-19 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CB4_RS04790 c5bd7d5935eff3798465b156c368a338 464 SUPERFAMILY SSF69796 323 449 1.83E-14 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CB4_RS11115 b4e6367527680af393e9fa144312f937 75 Gene3D G3DSA:3.30.110.40 1 75 1.1E-26 T 29-03-2018 IPR001455 TusA-like domain CB4_RS11115 b4e6367527680af393e9fa144312f937 75 Pfam PF01206 Sulfurtransferase TusA 6 74 4.4E-23 T 29-03-2018 IPR001455 TusA-like domain CB4_RS11115 b4e6367527680af393e9fa144312f937 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 29-03-2018 IPR001455 TusA-like domain CB4_RS11115 b4e6367527680af393e9fa144312f937 75 SUPERFAMILY SSF64307 3 74 2.22E-23 T 29-03-2018 IPR001455 TusA-like domain CB4_RS17245 7d760bdd495ff66c675710cefb9fbd03 304 SUPERFAMILY SSF103481 201 302 3.14E-13 T 29-03-2018 CB4_RS17245 7d760bdd495ff66c675710cefb9fbd03 304 SUPERFAMILY SSF103481 54 154 6.02E-12 T 29-03-2018 CB4_RS17245 7d760bdd495ff66c675710cefb9fbd03 304 Pfam PF00892 EamA-like transporter family 166 300 3.5E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS17245 7d760bdd495ff66c675710cefb9fbd03 304 Pfam PF00892 EamA-like transporter family 17 153 1.2E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS10005 01a371f766a461e62383bf60e1b6cf39 242 Gene3D G3DSA:3.40.50.1860 1 117 3.7E-35 T 29-03-2018 CB4_RS10005 01a371f766a461e62383bf60e1b6cf39 242 SUPERFAMILY SSF53681 1 112 1.41E-33 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS10005 01a371f766a461e62383bf60e1b6cf39 242 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 87 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS10005 01a371f766a461e62383bf60e1b6cf39 242 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 226 2.8E-49 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS10005 01a371f766a461e62383bf60e1b6cf39 242 Gene3D G3DSA:3.40.50.1860 118 227 2.8E-12 T 29-03-2018 CB4_RS10005 01a371f766a461e62383bf60e1b6cf39 242 SUPERFAMILY SSF53681 121 230 1.21E-12 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CB4_RS10005 01a371f766a461e62383bf60e1b6cf39 242 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 233 2.7E-49 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CB4_RS10115 df0c836e74fd86c1cb07dd6f6a5936c2 104 SUPERFAMILY SSF52821 6 97 7.2E-31 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS10115 df0c836e74fd86c1cb07dd6f6a5936c2 104 Gene3D G3DSA:3.40.250.10 2 100 4.4E-27 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS10115 df0c836e74fd86c1cb07dd6f6a5936c2 104 SMART SM00450 7 103 4.9E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS10115 df0c836e74fd86c1cb07dd6f6a5936c2 104 Pfam PF00581 Rhodanese-like domain 11 98 4.4E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CB4_RS13220 fb5ee19b25afcaeea23eae0c3543a8d0 107 Gene3D G3DSA:1.10.10.10 26 84 2.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13220 fb5ee19b25afcaeea23eae0c3543a8d0 107 SUPERFAMILY SSF46785 12 97 2.09E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13220 fb5ee19b25afcaeea23eae0c3543a8d0 107 Pfam PF03551 Transcriptional regulator PadR-like family 20 84 4.0E-15 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CB4_RS16185 86ca874baef0ea862f36c52070d66b1b 159 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 18 156 1.2E-63 T 29-03-2018 IPR014203 Sporulation stage V, protein AC CB4_RS16185 86ca874baef0ea862f36c52070d66b1b 159 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 35 152 4.9E-40 T 29-03-2018 IPR005562 SpoVA CB4_RS14915 c68aecc7688c3ca575af9597355b7678 582 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 352 533 7.0E-45 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14915 c68aecc7688c3ca575af9597355b7678 582 SUPERFAMILY SSF58104 244 278 3.66E-68 T 29-03-2018 CB4_RS14915 c68aecc7688c3ca575af9597355b7678 582 SUPERFAMILY SSF58104 311 580 3.66E-68 T 29-03-2018 CB4_RS14915 c68aecc7688c3ca575af9597355b7678 582 Gene3D G3DSA:3.30.450.20 31 202 6.1E-7 T 29-03-2018 CB4_RS14915 c68aecc7688c3ca575af9597355b7678 582 SMART SM00283 305 580 5.4E-68 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS14915 c68aecc7688c3ca575af9597355b7678 582 Pfam PF00672 HAMP domain 224 268 1.3E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14915 c68aecc7688c3ca575af9597355b7678 582 SMART SM00304 360 416 87.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14915 c68aecc7688c3ca575af9597355b7678 582 SMART SM00304 224 276 4.0E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CB4_RS14915 c68aecc7688c3ca575af9597355b7678 582 Gene3D G3DSA:1.10.287.950 343 582 1.2E-51 T 29-03-2018 CB4_RS14915 c68aecc7688c3ca575af9597355b7678 582 Gene3D G3DSA:1.10.287.950 232 342 1.3E-10 T 29-03-2018 CB4_RS01200 b005caa1a5d38ac253b74fa31f25bd3f 133 SUPERFAMILY SSF69065 9 126 2.09E-39 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CB4_RS01200 b005caa1a5d38ac253b74fa31f25bd3f 133 Gene3D G3DSA:1.10.1520.10 4 133 2.3E-16 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CB4_RS01200 b005caa1a5d38ac253b74fa31f25bd3f 133 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 7 131 29.662 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family CB4_RS01200 b005caa1a5d38ac253b74fa31f25bd3f 133 PIRSF PIRSF005520 1 133 1.2E-50 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family CB4_RS01200 b005caa1a5d38ac253b74fa31f25bd3f 133 Pfam PF00636 Ribonuclease III domain 17 112 5.2E-15 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CB4_RS15160 dfb6c2c02fbed06038d3c9f74f3c88b2 318 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 318 2.0E-139 T 29-03-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 CB4_RS15160 dfb6c2c02fbed06038d3c9f74f3c88b2 318 Pfam PF00348 Polyprenyl synthetase 30 258 1.9E-67 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CB4_RS15160 dfb6c2c02fbed06038d3c9f74f3c88b2 318 SUPERFAMILY SSF48576 4 317 1.04E-86 T 29-03-2018 IPR008949 Isoprenoid synthase domain CB4_RS15160 dfb6c2c02fbed06038d3c9f74f3c88b2 318 Gene3D G3DSA:1.10.600.10 1 318 9.4E-96 T 29-03-2018 IPR008949 Isoprenoid synthase domain CB4_RS15160 dfb6c2c02fbed06038d3c9f74f3c88b2 318 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CB4_RS15160 dfb6c2c02fbed06038d3c9f74f3c88b2 318 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CB4_RS05465 f655f43fc8302719f7c1f6928fce3d48 305 Gene3D G3DSA:3.40.50.720 1 163 2.1E-34 T 29-03-2018 CB4_RS05465 f655f43fc8302719f7c1f6928fce3d48 305 Gene3D G3DSA:3.90.25.10 164 305 8.8E-44 T 29-03-2018 CB4_RS05465 f655f43fc8302719f7c1f6928fce3d48 305 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 233 4.1E-63 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CB4_RS05465 f655f43fc8302719f7c1f6928fce3d48 305 SUPERFAMILY SSF51735 1 302 4.24E-99 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS17160 aeba3698d01223bcec00043d04088aac 275 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 162 182 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CB4_RS17160 aeba3698d01223bcec00043d04088aac 275 PIRSF PIRSF000090 1 267 3.0E-86 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CB4_RS17160 aeba3698d01223bcec00043d04088aac 275 Gene3D G3DSA:3.40.50.620 1 267 4.5E-74 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS17160 aeba3698d01223bcec00043d04088aac 275 Pfam PF01012 Electron transfer flavoprotein domain 23 213 2.0E-45 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CB4_RS17160 aeba3698d01223bcec00043d04088aac 275 SUPERFAMILY SSF52402 1 261 4.9E-73 T 29-03-2018 CB4_RS17160 aeba3698d01223bcec00043d04088aac 275 SMART SM00893 22 217 1.1E-58 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CB4_RS05345 9db082ac378860748ed12e0cfab28df5 433 Pfam PF10117 McrBC 5-methylcytosine restriction system component 67 384 2.4E-91 T 29-03-2018 IPR019292 5-methylcytosine restriction system component CB4_RS15040 6d1400e5214c7d22393849d979a4cfa0 198 Pfam PF07187 Protein of unknown function (DUF1405) 27 186 2.3E-53 T 29-03-2018 IPR009845 Protein of unknown function DUF1405 CB4_RS19800 155ed9ec16e34f208a531259dc73332b 201 Pfam PF00856 SET domain 69 112 4.8E-5 T 29-03-2018 IPR001214 SET domain GO:0005515 CB4_RS19800 155ed9ec16e34f208a531259dc73332b 201 SUPERFAMILY SSF82199 12 119 3.14E-14 T 29-03-2018 CB4_RS19800 155ed9ec16e34f208a531259dc73332b 201 Gene3D G3DSA:2.170.270.10 1 115 3.8E-12 T 29-03-2018 CB4_RS02930 b565efc216b1829244a0b1c2bc4c3bac 933 Gene3D G3DSA:2.60.120.430 585 734 5.2E-31 T 29-03-2018 CB4_RS02930 b565efc216b1829244a0b1c2bc4c3bac 933 Pfam PF00395 S-layer homology domain 880 922 2.4E-8 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02930 b565efc216b1829244a0b1c2bc4c3bac 933 Pfam PF00395 S-layer homology domain 815 856 1.3E-12 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02930 b565efc216b1829244a0b1c2bc4c3bac 933 Pfam PF00395 S-layer homology domain 754 794 2.5E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS02930 b565efc216b1829244a0b1c2bc4c3bac 933 Gene3D G3DSA:2.60.40.1080 405 484 0.0093 T 29-03-2018 CB4_RS02930 b565efc216b1829244a0b1c2bc4c3bac 933 Pfam PF09992 Phosphodiester glycosidase 216 395 3.9E-35 T 29-03-2018 IPR018711 Phosphodiester glycosidase CB4_RS19130 443a8ec043685184ef8d54f8904e3039 201 Pfam PF02659 Putative manganese efflux pump 65 196 2.7E-11 T 29-03-2018 IPR003810 Putative manganese efflux pump CB4_RS19130 443a8ec043685184ef8d54f8904e3039 201 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 4 199 1.9E-46 T 29-03-2018 IPR014205 Sporulation protein YtaF CB4_RS17860 b31647b0d5d6c4c3f128f531527af1b4 84 Pfam PF11084 Protein of unknown function (DUF2621) 2 83 1.7E-20 T 29-03-2018 IPR020203 Uncharacterised protein family, YneK CB4_RS17860 b31647b0d5d6c4c3f128f531527af1b4 84 Pfam PF08369 Proto-chlorophyllide reductase 57 kD subunit 3 51 6.0E-10 T 29-03-2018 IPR013580 Proto-chlorophyllide/chlorophyllide reductase, C-terminal GO:0015979|GO:0015995|GO:0016491|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 CB4_RS17860 b31647b0d5d6c4c3f128f531527af1b4 84 ProDom PD086666 YNEK BH2332 3 83 2.0E-11 T 29-03-2018 IPR020203 Uncharacterised protein family, YneK CB4_RS10800 fdd5117254224f7eae0b22475f5e53cf 683 SUPERFAMILY SSF52540 481 650 2.4E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10800 fdd5117254224f7eae0b22475f5e53cf 683 SUPERFAMILY SSF52540 435 449 2.4E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10800 fdd5117254224f7eae0b22475f5e53cf 683 SUPERFAMILY SSF52540 190 263 2.4E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10800 fdd5117254224f7eae0b22475f5e53cf 683 SUPERFAMILY SSF52540 38 95 2.4E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10800 fdd5117254224f7eae0b22475f5e53cf 683 SMART SM00491 521 654 8.6E-28 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CB4_RS10800 fdd5117254224f7eae0b22475f5e53cf 683 Pfam PF04851 Type III restriction enzyme, res subunit 25 265 1.4E-6 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CB4_RS10800 fdd5117254224f7eae0b22475f5e53cf 683 Gene3D G3DSA:3.40.50.300 24 468 1.0E-28 T 29-03-2018 CB4_RS10800 fdd5117254224f7eae0b22475f5e53cf 683 Gene3D G3DSA:3.40.50.300 489 653 4.0E-10 T 29-03-2018 CB4_RS10800 fdd5117254224f7eae0b22475f5e53cf 683 Pfam PF13307 Helicase C-terminal domain 505 667 9.3E-37 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CB4_RS10800 fdd5117254224f7eae0b22475f5e53cf 683 SMART SM00487 23 305 3.7E-5 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS18750 ed44b93e36bc02b6ff82410eec129b17 132 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 114 7.2E-15 T 29-03-2018 CB4_RS18750 ed44b93e36bc02b6ff82410eec129b17 132 Gene3D G3DSA:3.10.180.10 1 132 8.5E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS18750 ed44b93e36bc02b6ff82410eec129b17 132 SUPERFAMILY SSF54593 1 128 4.83E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS18335 7e83939e818578b98e2ed30beee6099b 155 Pfam PF03477 ATP cone domain 50 136 3.7E-18 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CB4_RS18335 7e83939e818578b98e2ed30beee6099b 155 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 7.9E-69 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CB4_RS18335 7e83939e818578b98e2ed30beee6099b 155 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 87.563 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CB4_RS15310 84c5b8d32153e77ee2f605d89e906402 280 Gene3D G3DSA:1.10.287.860 150 198 4.0E-19 T 29-03-2018 CB4_RS15310 84c5b8d32153e77ee2f605d89e906402 280 Gene3D G3DSA:3.30.460.10 1 148 1.2E-35 T 29-03-2018 CB4_RS15310 84c5b8d32153e77ee2f605d89e906402 280 Pfam PF04607 Region found in RelA / SpoT proteins 45 165 4.4E-35 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CB4_RS15310 84c5b8d32153e77ee2f605d89e906402 280 SUPERFAMILY SSF81301 5 200 1.5E-55 T 29-03-2018 CB4_RS15310 84c5b8d32153e77ee2f605d89e906402 280 SMART SM00954 45 167 2.6E-39 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CB4_RS11205 dd53cbab156c3c0fd3448cb38de9dff4 458 Pfam PF04932 O-Antigen ligase 244 391 2.3E-15 T 29-03-2018 IPR007016 O-antigen ligase-related CB4_RS04810 712639aab43b62373b4d3cec814af1e5 100 Pfam PF01740 STAS domain 14 97 4.2E-15 T 29-03-2018 IPR002645 STAS domain CB4_RS04810 712639aab43b62373b4d3cec814af1e5 100 SUPERFAMILY SSF52091 5 99 3.14E-24 T 29-03-2018 IPR002645 STAS domain CB4_RS04810 712639aab43b62373b4d3cec814af1e5 100 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 9 99 2.5E-20 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CB4_RS04810 712639aab43b62373b4d3cec814af1e5 100 Gene3D G3DSA:3.30.750.24 9 100 1.0E-16 T 29-03-2018 IPR002645 STAS domain CB4_RS01095 65c51f3bc8a6674366d9e2c28785b0c1 395 Pfam PF01098 Cell cycle protein 11 366 5.7E-106 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CB4_RS01095 65c51f3bc8a6674366d9e2c28785b0c1 395 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 8 365 3.6E-111 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CB4_RS15865 53f2037b8a9b7e30392e94eebdd70780 322 SUPERFAMILY SSF143865 2 257 1.31E-60 T 29-03-2018 CB4_RS15865 53f2037b8a9b7e30392e94eebdd70780 322 Gene3D G3DSA:1.20.58.340 256 322 1.3E-15 T 29-03-2018 CB4_RS15865 53f2037b8a9b7e30392e94eebdd70780 322 Gene3D G3DSA:1.20.58.340 136 255 7.1E-24 T 29-03-2018 CB4_RS15865 53f2037b8a9b7e30392e94eebdd70780 322 Gene3D G3DSA:3.30.460.20 1 135 3.2E-31 T 29-03-2018 CB4_RS15865 53f2037b8a9b7e30392e94eebdd70780 322 Pfam PF01544 CorA-like Mg2+ transporter protein 31 319 1.8E-67 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CB4_RS15865 53f2037b8a9b7e30392e94eebdd70780 322 SUPERFAMILY SSF144083 260 320 3.27E-14 T 29-03-2018 CB4_RS08760 462265bcb88f07fc1a394a835de17878 124 SMART SM00530 6 61 1.1E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS08760 462265bcb88f07fc1a394a835de17878 124 Gene3D G3DSA:1.10.3100.10 1 124 1.5E-25 T 29-03-2018 IPR027910 YdiL-like domain CB4_RS08760 462265bcb88f07fc1a394a835de17878 124 Pfam PF01381 Helix-turn-helix 7 61 4.2E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS08760 462265bcb88f07fc1a394a835de17878 124 SUPERFAMILY SSF47413 2 68 1.18E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS18830 a7ce939713b82ce2db5acfd00ba51e19 276 Pfam PF04293 SpoVR like protein 4 272 1.3E-112 T 29-03-2018 IPR007390 Sporulation stage V, protein R CB4_RS04920 38cabb0305804a8b7d12ba4a4a603012 151 Pfam PF02566 OsmC-like protein 42 146 2.0E-19 T 29-03-2018 IPR003718 OsmC/Ohr family CB4_RS04920 38cabb0305804a8b7d12ba4a4a603012 151 Gene3D G3DSA:3.30.300.20 2 151 6.3E-30 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CB4_RS04920 38cabb0305804a8b7d12ba4a4a603012 151 SUPERFAMILY SSF82784 9 148 3.4E-36 T 29-03-2018 IPR003718 OsmC/Ohr family CB4_RS19305 05b26d76d46f970e139d86cb547e43c3 108 Gene3D G3DSA:3.30.70.100 1 98 1.0E-5 T 29-03-2018 CB4_RS19305 05b26d76d46f970e139d86cb547e43c3 108 Pfam PF05977 Transmembrane secretion effector 4 68 1.0E-5 T 29-03-2018 IPR010290 Transmembrane secretion effector CB4_RS02990 36e4e2cd0102c40fbd60735808df5b19 162 Gene3D G3DSA:3.40.50.2300 1 161 2.8E-51 T 29-03-2018 CB4_RS02990 36e4e2cd0102c40fbd60735808df5b19 162 SUPERFAMILY SSF52788 5 154 6.02E-47 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CB4_RS02990 36e4e2cd0102c40fbd60735808df5b19 162 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 9 151 1.1E-40 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CB4_RS02990 36e4e2cd0102c40fbd60735808df5b19 162 SMART SM00226 7 153 5.9E-53 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CB4_RS02990 36e4e2cd0102c40fbd60735808df5b19 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 125 140 2.3E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CB4_RS02990 36e4e2cd0102c40fbd60735808df5b19 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 86 101 2.3E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CB4_RS02990 36e4e2cd0102c40fbd60735808df5b19 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 52 68 2.3E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CB4_RS02990 36e4e2cd0102c40fbd60735808df5b19 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 9 26 2.3E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CB4_RS15430 59aaeda343001de3fa96093f341a3fb3 149 Pfam PF10934 Protein of unknown function (DUF2634) 34 133 5.7E-14 T 29-03-2018 IPR020288 Protein of unknown function DUF2634 CB4_RS15430 59aaeda343001de3fa96093f341a3fb3 149 Gene3D G3DSA:3.10.450.40 27 146 1.6E-4 T 29-03-2018 CB4_RS16315 d3a41123376bb7f2aafb494c1c8b0fc7 159 Pfam PF01475 Ferric uptake regulator family 15 136 2.0E-36 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CB4_RS16315 d3a41123376bb7f2aafb494c1c8b0fc7 159 SUPERFAMILY SSF46785 6 141 5.44E-37 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16315 d3a41123376bb7f2aafb494c1c8b0fc7 159 Gene3D G3DSA:1.10.10.10 8 97 3.6E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS12100 cac3d0436904fdbc086a327c435e0de1 63 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 62 3.9E-26 T 29-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CB4_RS12100 cac3d0436904fdbc086a327c435e0de1 63 SUPERFAMILY SSF55331 2 61 5.89E-21 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CB4_RS12100 cac3d0436904fdbc086a327c435e0de1 63 Gene3D G3DSA:3.30.429.10 1 63 3.3E-22 T 29-03-2018 CB4_RS12100 cac3d0436904fdbc086a327c435e0de1 63 Pfam PF01361 Tautomerase enzyme 2 59 1.9E-22 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CB4_RS12065 c0b041d7d42e36b2d4f560436d001ff3 141 SUPERFAMILY SSF143744 3 138 1.22E-40 T 29-03-2018 CB4_RS12065 c0b041d7d42e36b2d4f560436d001ff3 141 Pfam PF03928 Haem-degrading 10 136 7.1E-35 T 29-03-2018 IPR005624 Haem-degrading CB4_RS08755 7e66cad2113742b53e457446713f8422 150 Pfam PF14472 Domain of unknown function (DUF4429) 16 96 1.2E-7 T 29-03-2018 IPR027860 Domain of unknown function DUF4429 CB4_RS08755 7e66cad2113742b53e457446713f8422 150 Pfam PF09851 Short C-terminal domain 121 148 3.3E-9 T 29-03-2018 IPR018649 SHOCT domain CB4_RS14865 3ea6fa998227010f24c5cba14742d58a 195 Gene3D G3DSA:1.10.10.60 5 63 5.6E-17 T 29-03-2018 CB4_RS14865 3ea6fa998227010f24c5cba14742d58a 195 SUPERFAMILY SSF46689 6 61 5.64E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS14865 3ea6fa998227010f24c5cba14742d58a 195 SUPERFAMILY SSF48498 83 193 8.56E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CB4_RS14865 3ea6fa998227010f24c5cba14742d58a 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS14865 3ea6fa998227010f24c5cba14742d58a 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS14865 3ea6fa998227010f24c5cba14742d58a 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 4.3E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS14865 3ea6fa998227010f24c5cba14742d58a 195 Gene3D G3DSA:1.10.357.10 64 195 3.5E-12 T 29-03-2018 CB4_RS19495 af5e833dff09c69ab85812bf4cd7b577 476 Pfam PF03023 MviN-like protein 41 458 1.2E-61 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS19495 af5e833dff09c69ab85812bf4cd7b577 476 PRINTS PR01806 Virulence factor MviN signature 282 308 3.0E-17 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS19495 af5e833dff09c69ab85812bf4cd7b577 476 PRINTS PR01806 Virulence factor MviN signature 143 167 3.0E-17 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS19495 af5e833dff09c69ab85812bf4cd7b577 476 PRINTS PR01806 Virulence factor MviN signature 167 188 3.0E-17 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS19495 af5e833dff09c69ab85812bf4cd7b577 476 PRINTS PR01806 Virulence factor MviN signature 45 64 3.0E-17 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS19495 af5e833dff09c69ab85812bf4cd7b577 476 PRINTS PR01806 Virulence factor MviN signature 380 399 3.0E-17 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS19495 af5e833dff09c69ab85812bf4cd7b577 476 PRINTS PR01806 Virulence factor MviN signature 432 449 3.0E-17 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CB4_RS04125 a4d110e31407a5205d8d5039e3bd20fc 193 Pfam PF04367 Protein of unknown function (DUF502) 54 154 5.8E-22 T 29-03-2018 IPR007462 Protein of unknown function DUF502 CB4_RS19175 685f9d715a95d2f6613c528b5a92cd09 264 Pfam PF06182 ABC-2 family transporter protein 32 257 3.0E-22 T 29-03-2018 IPR010390 Protein of unknown function DUF990 CB4_RS08340 94b0c0c0c49f722171f91dd24d2dbe7e 147 Hamap MF_01197 Cell division protein SepF [sepF]. 1 142 18.819 T 29-03-2018 IPR023052 Cell division protein SepF GO:0090529 CB4_RS08340 94b0c0c0c49f722171f91dd24d2dbe7e 147 Pfam PF04472 Cell division protein SepF 64 134 6.1E-25 T 29-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CB4_RS07395 bd824b7ba2f1177a6f2c8d4e921ba182 420 SUPERFAMILY SSF111352 10 385 5.49E-110 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CB4_RS07395 bd824b7ba2f1177a6f2c8d4e921ba182 420 TIGRFAM TIGR00836 amt: ammonium transporter 12 403 3.2E-123 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CB4_RS07395 bd824b7ba2f1177a6f2c8d4e921ba182 420 Gene3D G3DSA:1.10.3430.10 28 402 4.2E-120 T 29-03-2018 CB4_RS07395 bd824b7ba2f1177a6f2c8d4e921ba182 420 Pfam PF00909 Ammonium Transporter Family 14 403 1.3E-118 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 Gene3D G3DSA:1.20.1250.20 4 196 5.2E-34 T 29-03-2018 CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 Gene3D G3DSA:1.20.1250.20 257 516 1.3E-28 T 29-03-2018 CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 501 3.5E-154 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 Pfam PF07690 Major Facilitator Superfamily 17 407 3.9E-55 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 2.8E-10 T 29-03-2018 CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 2.8E-10 T 29-03-2018 CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 300 324 2.8E-10 T 29-03-2018 CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 2.8E-10 T 29-03-2018 CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 SUPERFAMILY SSF103473 478 506 9.29E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 SUPERFAMILY SSF103473 7 195 9.29E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS13010 54fa607ac717bd1d0f67b14225bc83da 530 SUPERFAMILY SSF103473 246 417 9.29E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS19340 0980e5dab21d199e1159a995499bb71c 204 SUPERFAMILY SSF52540 24 196 4.18E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19340 0980e5dab21d199e1159a995499bb71c 204 Gene3D G3DSA:3.40.50.300 24 202 2.9E-55 T 29-03-2018 CB4_RS19340 0980e5dab21d199e1159a995499bb71c 204 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 26 198 39.103 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CB4_RS19340 0980e5dab21d199e1159a995499bb71c 204 Pfam PF01583 Adenylylsulphate kinase 28 181 4.9E-72 T 29-03-2018 CB4_RS19340 0980e5dab21d199e1159a995499bb71c 204 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 10 194 2.1E-84 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CB4_RS03155 33634086a145ec54d04a664dd780f8e3 286 SUPERFAMILY SSF53335 27 226 7.19E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS03155 33634086a145ec54d04a664dd780f8e3 286 Gene3D G3DSA:3.40.50.150 50 265 7.6E-11 T 29-03-2018 CB4_RS03155 33634086a145ec54d04a664dd780f8e3 286 Pfam PF13489 Methyltransferase domain 71 226 3.1E-6 T 29-03-2018 CB4_RS06190 d5b1e62e0c8dab235328c20ab080c115 164 Gene3D G3DSA:3.90.1340.10 1 67 5.1E-22 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS06190 d5b1e62e0c8dab235328c20ab080c115 164 Pfam PF07484 Phage Tail Collar Domain 7 63 8.1E-27 T 29-03-2018 IPR011083 Phage tail collar domain CB4_RS06190 d5b1e62e0c8dab235328c20ab080c115 164 SUPERFAMILY SSF88874 1 158 1.92E-46 T 29-03-2018 CB4_RS06870 2889ca4fbf1e86cc77355ba52f20168d 357 Gene3D G3DSA:3.55.50.10 1 63 1.1E-7 T 29-03-2018 CB4_RS06870 2889ca4fbf1e86cc77355ba52f20168d 357 SUPERFAMILY SSF69279 1 54 1.96E-8 T 29-03-2018 CB4_RS08470 259118c90f806a10a6a8e778b0be7121 65 SUPERFAMILY SSF63562 1 64 7.85E-20 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CB4_RS08470 259118c90f806a10a6a8e778b0be7121 65 SMART SM01409 8 61 1.4E-15 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CB4_RS08470 259118c90f806a10a6a8e778b0be7121 65 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 1.7E-14 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS08470 259118c90f806a10a6a8e778b0be7121 65 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 15.054 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CB4_RS08470 259118c90f806a10a6a8e778b0be7121 65 Pfam PF01192 RNA polymerase Rpb6 8 61 3.2E-14 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CB4_RS08470 259118c90f806a10a6a8e778b0be7121 65 Gene3D G3DSA:3.90.940.10 1 65 3.5E-19 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CB4_RS06555 ae1dff39b32a90a74cbdde63a1484cf4 114 SUPERFAMILY SSF81301 2 112 1.24E-40 T 29-03-2018 CB4_RS06555 ae1dff39b32a90a74cbdde63a1484cf4 114 Gene3D G3DSA:3.30.460.10 1 108 4.2E-31 T 29-03-2018 CB4_RS06555 ae1dff39b32a90a74cbdde63a1484cf4 114 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 1.9E-35 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CB4_RS06555 ae1dff39b32a90a74cbdde63a1484cf4 114 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 1.5E-25 T 29-03-2018 CB4_RS06555 ae1dff39b32a90a74cbdde63a1484cf4 114 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 105 24.988 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CB4_RS17210 79d21031c3cd55f801a5440015d95774 739 Pfam PF04536 TPM domain 42 157 7.6E-7 T 29-03-2018 IPR007621 TPM domain CB4_RS17210 79d21031c3cd55f801a5440015d95774 739 Gene3D G3DSA:1.10.287.950 627 710 0.068 T 29-03-2018 CB4_RS17210 79d21031c3cd55f801a5440015d95774 739 Gene3D G3DSA:1.10.287.950 378 525 0.24 T 29-03-2018 CB4_RS17210 79d21031c3cd55f801a5440015d95774 739 Gene3D G3DSA:1.20.58.60 259 371 0.0087 T 29-03-2018 CB4_RS17210 79d21031c3cd55f801a5440015d95774 739 Pfam PF06160 Septation ring formation regulator, EzrA 193 728 5.6E-66 T 29-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CB4_RS17210 79d21031c3cd55f801a5440015d95774 739 Gene3D G3DSA:1.20.58.400 530 624 3.7E-4 T 29-03-2018 CB4_RS07000 111c42d6b86f5f94d33cc1914ebcf03a 166 Pfam PF07552 Spore Coat Protein X and V domain 46 102 5.7E-17 T 29-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CB4_RS07000 111c42d6b86f5f94d33cc1914ebcf03a 166 Pfam PF07552 Spore Coat Protein X and V domain 110 161 2.3E-15 T 29-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 SUPERFAMILY SSF81271 377 449 1.57E-22 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 Pfam PF02824 TGS domain 390 449 4.7E-23 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 SUPERFAMILY SSF81301 193 367 7.52E-68 T 29-03-2018 CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 Gene3D G3DSA:3.10.20.30 384 457 2.2E-24 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 27 719 2.0E-257 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 SMART SM00471 42 154 4.7E-9 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 Gene3D G3DSA:3.30.460.10 189 327 1.4E-46 T 29-03-2018 CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 Pfam PF13328 HD domain 27 176 3.9E-55 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 Pfam PF13291 ACT domain 643 719 7.1E-21 T 29-03-2018 IPR002912 ACT domain CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 SUPERFAMILY SSF55021 645 722 2.25E-13 T 29-03-2018 CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 Pfam PF04607 Region found in RelA / SpoT proteins 236 346 4.0E-40 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 SMART SM00954 236 346 1.7E-70 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 SUPERFAMILY SSF109604 6 191 4.39E-75 T 29-03-2018 CB4_RS06005 1b2f7c95939417c9ccb5e1900985abc7 723 Gene3D G3DSA:3.30.70.260 642 723 1.3E-13 T 29-03-2018 CB4_RS03475 f8e65e6e4855d8a7283f56b46c979ea4 139 SUPERFAMILY SSF160544 17 93 5.1E-20 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CB4_RS03475 f8e65e6e4855d8a7283f56b46c979ea4 139 Gene3D G3DSA:3.40.1690.10 17 94 7.4E-24 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CB4_RS03475 f8e65e6e4855d8a7283f56b46c979ea4 139 Pfam PF01312 FlhB HrpN YscU SpaS Family 19 91 7.0E-15 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CB4_RS18550 1394a4990f08063586dc9c6d2074e0e1 388 Pfam PF00155 Aminotransferase class I and II 30 376 5.9E-62 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CB4_RS18550 1394a4990f08063586dc9c6d2074e0e1 388 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CB4_RS18550 1394a4990f08063586dc9c6d2074e0e1 388 Gene3D G3DSA:3.90.1150.10 268 387 2.0E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS18550 1394a4990f08063586dc9c6d2074e0e1 388 SUPERFAMILY SSF53383 4 384 6.32E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS18550 1394a4990f08063586dc9c6d2074e0e1 388 Gene3D G3DSA:3.40.640.10 42 267 1.2E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS08890 8b54546d29f0071958a04c65d8a0ef17 107 Pfam PF05119 Phage terminase, small subunit 17 99 4.8E-13 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CB4_RS08890 8b54546d29f0071958a04c65d8a0ef17 107 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 16 104 6.0E-17 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CB4_RS16470 5a7e3fcb56e2e70ce33fdb9661469932 228 Pfam PF04298 Putative neutral zinc metallopeptidase 7 221 1.7E-87 T 29-03-2018 IPR007395 Putative neutral zinc metallopeptidase CB4_RS12265 a6ce3bc9460ab13e981d5b29c9d60efd 164 Pfam PF02559 CarD-like/TRCF domain 7 114 1.1E-16 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS12265 a6ce3bc9460ab13e981d5b29c9d60efd 164 SUPERFAMILY SSF141259 7 67 3.27E-14 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS12265 a6ce3bc9460ab13e981d5b29c9d60efd 164 SMART SM01058 6 116 1.5E-29 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS06225 ca7ec44259c3e8cbbf6f3f6d17e0ab3b 97 Pfam PF10850 Protein of unknown function (DUF2653) 2 84 3.0E-18 T 29-03-2018 IPR020516 Uncharacterised protein family YxcD CB4_RS06225 ca7ec44259c3e8cbbf6f3f6d17e0ab3b 97 ProDom PD068665 YXCD 3 92 6.0E-8 T 29-03-2018 IPR020516 Uncharacterised protein family YxcD CB4_RS04195 f747115babce87681db80849b31ce003 551 Pfam PF02652 L-lactate permease 16 542 1.1E-217 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CB4_RS04195 f747115babce87681db80849b31ce003 551 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 544 2.7E-225 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CB4_RS06255 26f5795b78942bf3c4e36cbf83b4615c 81 Pfam PF03698 Uncharacterised protein family (UPF0180) 3 77 1.2E-29 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 CB4_RS06255 26f5795b78942bf3c4e36cbf83b4615c 81 Hamap MF_00506 UPF0180 protein . 1 79 25.693 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 CB4_RS06255 26f5795b78942bf3c4e36cbf83b4615c 81 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 1 47 4.0E-11 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 CB4_RS16945 a90e3de3d2794860cbfbb7a541b5ff21 324 SUPERFAMILY SSF100950 3 322 1.26E-79 T 29-03-2018 CB4_RS16945 a90e3de3d2794860cbfbb7a541b5ff21 324 SMART SM00882 5 245 1.2E-27 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CB4_RS16945 a90e3de3d2794860cbfbb7a541b5ff21 324 Pfam PF01144 Coenzyme A transferase 7 244 1.3E-27 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CB4_RS16945 a90e3de3d2794860cbfbb7a541b5ff21 324 Gene3D G3DSA:3.40.1080.10 3 322 3.1E-62 T 29-03-2018 CB4_RS14095 50fad7964362cb34646ab97f94bb3f08 422 SUPERFAMILY SSF53383 51 398 1.12E-46 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS14095 50fad7964362cb34646ab97f94bb3f08 422 Pfam PF06838 Methionine gamma-lyase 15 414 4.7E-195 T 29-03-2018 IPR009651 Putative methionine gamma-lyase CB4_RS14095 50fad7964362cb34646ab97f94bb3f08 422 Gene3D G3DSA:3.40.640.10 58 271 9.3E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS14630 e2fdcfbb9a875e902651841e0dc29b40 126 Gene3D G3DSA:1.10.10.10 49 122 7.0E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS02295 b41de9b4911849d71535acc0e56d1c3a 200 SUPERFAMILY SSF81452 7 198 1.44E-57 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02295 b41de9b4911849d71535acc0e56d1c3a 200 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 21 200 1.8E-71 T 29-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 CB4_RS02295 b41de9b4911849d71535acc0e56d1c3a 200 Gene3D G3DSA:1.20.120.80 15 200 1.2E-52 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS02295 b41de9b4911849d71535acc0e56d1c3a 200 Pfam PF00510 Cytochrome c oxidase subunit III 11 198 3.7E-19 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS09745 b8db6c3649e09ff84795e939dcc6e38f 169 SUPERFAMILY SSF56281 11 159 1.17E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS07895 4f5755598b9705206bf59ee598286fc5 173 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 172 6.1E-52 T 29-03-2018 IPR014198 Stage III sporulation protein AB CB4_RS07895 4f5755598b9705206bf59ee598286fc5 173 PIRSF PIRSF021435 1 173 5.3E-50 T 29-03-2018 IPR014198 Stage III sporulation protein AB CB4_RS07895 4f5755598b9705206bf59ee598286fc5 173 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 172 3.1E-54 T 29-03-2018 IPR014198 Stage III sporulation protein AB CB4_RS09340 30dacdc65b952a4bcc461015f7ad06bd 331 Pfam PF02272 DHHA1 domain 234 318 6.8E-11 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CB4_RS09340 30dacdc65b952a4bcc461015f7ad06bd 331 Pfam PF01368 DHH family 20 161 2.3E-12 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CB4_RS09340 30dacdc65b952a4bcc461015f7ad06bd 331 Gene3D G3DSA:3.90.1640.10 2 203 6.6E-44 T 29-03-2018 CB4_RS09340 30dacdc65b952a4bcc461015f7ad06bd 331 SUPERFAMILY SSF64182 18 319 3.4E-64 T 29-03-2018 CB4_RS04395 81bb9bffe87bef640dcf2c4b6b4be02d 415 Gene3D G3DSA:3.40.605.10 2 233 6.9E-45 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS04395 81bb9bffe87bef640dcf2c4b6b4be02d 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 10 405 7.9E-168 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CB4_RS04395 81bb9bffe87bef640dcf2c4b6b4be02d 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 322 344 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CB4_RS04395 81bb9bffe87bef640dcf2c4b6b4be02d 415 SUPERFAMILY SSF53720 7 415 1.7E-118 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS04395 81bb9bffe87bef640dcf2c4b6b4be02d 415 Gene3D G3DSA:3.40.605.10 234 415 1.0E-42 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS04395 81bb9bffe87bef640dcf2c4b6b4be02d 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 2 415 43.048 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CB4_RS04395 81bb9bffe87bef640dcf2c4b6b4be02d 415 Pfam PF00171 Aldehyde dehydrogenase family 8 279 3.9E-15 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS04395 81bb9bffe87bef640dcf2c4b6b4be02d 415 PIRSF PIRSF000151 1 415 1.5E-184 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CB4_RS15435 b5930b5700ebc312bf959688f055c1b5 142 Pfam PF10844 Protein of unknown function (DUF2577) 31 135 7.5E-5 T 29-03-2018 IPR022555 Protein of unknown function, DUF2577 CB4_RS16455 83b90c6eca2423dc714d640ad9c49a12 67 Pfam PF14169 Cold-inducible protein YdjO 6 61 9.1E-26 T 29-03-2018 IPR025916 Cold-inducible protein YdjO CB4_RS02605 6d7e8f87b1b2e0bdf002175e7b65c4ff 409 Pfam PF12698 ABC-2 family transporter protein 27 371 1.2E-26 T 29-03-2018 CB4_RS02605 6d7e8f87b1b2e0bdf002175e7b65c4ff 409 Gene3D G3DSA:3.40.1710.10 49 189 2.2E-15 T 29-03-2018 CB4_RS03025 7ecf30359b6be3ce4a1c06b3f4f482aa 168 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 18 160 9.6E-38 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS09860 bc66905d5ec2f4130f3df272b69c8e7d 284 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 77 283 1.0E-69 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS09860 bc66905d5ec2f4130f3df272b69c8e7d 284 SUPERFAMILY SSF56529 66 283 3.92E-78 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS09860 bc66905d5ec2f4130f3df272b69c8e7d 284 Gene3D G3DSA:3.90.850.10 28 284 8.2E-82 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS05175 eb8450e3cb34d4d93231b21b84b37d5b 377 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 5.1E-157 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS05175 eb8450e3cb34d4d93231b21b84b37d5b 377 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS05175 eb8450e3cb34d4d93231b21b84b37d5b 377 Gene3D G3DSA:3.90.1150.10 246 377 8.5E-52 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS05175 eb8450e3cb34d4d93231b21b84b37d5b 377 Gene3D G3DSA:3.40.640.10 1 245 1.3E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS05175 eb8450e3cb34d4d93231b21b84b37d5b 377 SUPERFAMILY SSF53383 5 376 1.26E-117 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS05175 eb8450e3cb34d4d93231b21b84b37d5b 377 PIRSF PIRSF001434 1 377 6.2E-149 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CB4_RS16725 e0f4e551b48da54ed0c60dbf2e1f836b 289 Gene3D G3DSA:3.20.20.370 49 289 7.7E-51 T 29-03-2018 CB4_RS16725 e0f4e551b48da54ed0c60dbf2e1f836b 289 Pfam PF01522 Polysaccharide deacetylase 96 217 1.3E-27 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS16725 e0f4e551b48da54ed0c60dbf2e1f836b 289 SUPERFAMILY SSF88713 91 283 6.43E-54 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS19415 2b7c0543d9c410ae52f879185e17c0d6 363 Pfam PF03845 Spore germination protein 12 315 1.0E-25 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS19415 2b7c0543d9c410ae52f879185e17c0d6 363 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 359 1.6E-57 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS01820 73aedab6c91c661854606776ee6455e9 371 Gene3D G3DSA:3.40.1830.10 2 165 6.7E-44 T 29-03-2018 IPR035097 Peptidase M29, N-terminal CB4_RS01820 73aedab6c91c661854606776ee6455e9 371 Pfam PF02073 Thermophilic metalloprotease (M29) 3 334 2.0E-59 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CB4_RS01820 73aedab6c91c661854606776ee6455e9 371 SUPERFAMILY SSF144052 1 360 3.27E-110 T 29-03-2018 CB4_RS20175 ee511584c17795cfab5bafb477341f2c 249 Gene3D G3DSA:3.40.50.1400 128 238 2.0E-10 T 29-03-2018 CB4_RS20175 ee511584c17795cfab5bafb477341f2c 249 SUPERFAMILY SSF53800 2 218 1.09E-22 T 29-03-2018 CB4_RS20175 ee511584c17795cfab5bafb477341f2c 249 Gene3D G3DSA:3.40.50.1400 1 127 3.9E-20 T 29-03-2018 CB4_RS20175 ee511584c17795cfab5bafb477341f2c 249 Pfam PF01903 CbiX 143 226 9.9E-5 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CB4_RS20175 ee511584c17795cfab5bafb477341f2c 249 Pfam PF01903 CbiX 10 123 5.5E-16 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CB4_RS00235 aedd653422709a7d6183ca1b0450836d 433 SUPERFAMILY SSF103473 12 391 2.62E-22 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS00235 aedd653422709a7d6183ca1b0450836d 433 Gene3D G3DSA:1.20.1250.20 198 396 0.0045 T 29-03-2018 CB4_RS00235 aedd653422709a7d6183ca1b0450836d 433 Gene3D G3DSA:1.20.1250.20 10 195 1.3E-13 T 29-03-2018 CB4_RS00235 aedd653422709a7d6183ca1b0450836d 433 Pfam PF07690 Major Facilitator Superfamily 23 329 1.4E-8 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS07705 a1d32fd66c6c36871d57b2739974a95b 489 Gene3D G3DSA:3.40.640.10 87 347 6.0E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CB4_RS07705 a1d32fd66c6c36871d57b2739974a95b 489 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 11 488 59.816 T 29-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CB4_RS07705 a1d32fd66c6c36871d57b2739974a95b 489 SUPERFAMILY SSF53383 34 486 1.32E-118 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CB4_RS07705 a1d32fd66c6c36871d57b2739974a95b 489 Pfam PF02347 Glycine cleavage system P-protein 53 389 2.4E-11 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CB4_RS07705 a1d32fd66c6c36871d57b2739974a95b 489 Gene3D G3DSA:3.90.1150.10 348 473 2.7E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CB4_RS01305 d2332a1802d07df1b92fdae12af44752 119 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 112 5.6E-16 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CB4_RS01305 d2332a1802d07df1b92fdae12af44752 119 Gene3D G3DSA:1.20.120.30 21 115 1.1E-7 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CB4_RS20265 2bf1eea77452c470f5c6c2d1468adbf1 143 Pfam PF13581 Histidine kinase-like ATPase domain 40 132 1.9E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS20265 2bf1eea77452c470f5c6c2d1468adbf1 143 Gene3D G3DSA:3.30.565.10 1 138 2.6E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS05740 2d09c7df0035bf29cf7a3450fc2ad389 164 Gene3D G3DSA:3.30.700.10 17 154 1.7E-4 T 29-03-2018 CB4_RS05740 2d09c7df0035bf29cf7a3450fc2ad389 164 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 35 6.9E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS05740 2d09c7df0035bf29cf7a3450fc2ad389 164 Pfam PF07963 Prokaryotic N-terminal methylation motif 13 35 1.3E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS05740 2d09c7df0035bf29cf7a3450fc2ad389 164 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 15 35 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS07140 e9173832ab3f28abe6576c6c4f259548 216 SMART SM00116 153 208 3.1 T 29-03-2018 IPR000644 CBS domain CB4_RS07140 e9173832ab3f28abe6576c6c4f259548 216 SMART SM00116 86 134 8.0E-5 T 29-03-2018 IPR000644 CBS domain CB4_RS07140 e9173832ab3f28abe6576c6c4f259548 216 Gene3D G3DSA:3.10.580.10 71 213 1.5E-25 T 29-03-2018 CB4_RS07140 e9173832ab3f28abe6576c6c4f259548 216 Pfam PF08279 HTH domain 9 61 1.1E-11 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CB4_RS07140 e9173832ab3f28abe6576c6c4f259548 216 PIRSF PIRSF026546 4 214 8.2E-96 T 29-03-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS CB4_RS07140 e9173832ab3f28abe6576c6c4f259548 216 SUPERFAMILY SSF46785 5 70 1.48E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07140 e9173832ab3f28abe6576c6c4f259548 216 Gene3D G3DSA:1.10.10.10 3 70 1.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS07140 e9173832ab3f28abe6576c6c4f259548 216 Pfam PF00571 CBS domain 148 205 1.1E-4 T 29-03-2018 IPR000644 CBS domain CB4_RS07140 e9173832ab3f28abe6576c6c4f259548 216 Pfam PF00571 CBS domain 85 133 4.3E-7 T 29-03-2018 IPR000644 CBS domain CB4_RS07140 e9173832ab3f28abe6576c6c4f259548 216 SUPERFAMILY SSF54631 72 209 4.3E-22 T 29-03-2018 CB4_RS09930 bc1f02d35dc1f47d6647727a55f247ae 281 Pfam PF06314 Acetoacetate decarboxylase (ADC) 26 278 3.8E-54 T 29-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CB4_RS09930 bc1f02d35dc1f47d6647727a55f247ae 281 Gene3D G3DSA:2.40.400.10 20 281 4.3E-54 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CB4_RS09930 bc1f02d35dc1f47d6647727a55f247ae 281 SUPERFAMILY SSF160104 34 277 1.19E-44 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CB4_RS10965 942d12bd341ef80e7fb4cf6592b10f97 141 SMART SM00226 6 139 1.1E-58 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CB4_RS10965 942d12bd341ef80e7fb4cf6592b10f97 141 SUPERFAMILY SSF52788 8 137 1.19E-44 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CB4_RS10965 942d12bd341ef80e7fb4cf6592b10f97 141 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 8 135 3.2E-71 T 29-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 CB4_RS10965 942d12bd341ef80e7fb4cf6592b10f97 141 Gene3D G3DSA:3.40.50.2300 3 138 3.3E-39 T 29-03-2018 CB4_RS10965 942d12bd341ef80e7fb4cf6592b10f97 141 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 136 1.1E-25 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CB4_RS03325 b01c3bcb3851f7b34f6ed77ae7ec0a2f 333 SUPERFAMILY SSF52266 241 329 4.81E-6 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CB4_RS03325 b01c3bcb3851f7b34f6ed77ae7ec0a2f 333 SUPERFAMILY SSF52266 58 139 4.81E-6 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CB4_RS03325 b01c3bcb3851f7b34f6ed77ae7ec0a2f 333 Gene3D G3DSA:3.40.50.1110 42 332 1.3E-12 T 29-03-2018 CB4_RS05645 1da227105bae1447823caccfd116751b 553 SUPERFAMILY SSF58104 216 250 6.93E-55 T 29-03-2018 CB4_RS05645 1da227105bae1447823caccfd116751b 553 SUPERFAMILY SSF58104 283 551 6.93E-55 T 29-03-2018 CB4_RS05645 1da227105bae1447823caccfd116751b 553 SMART SM00283 277 552 6.0E-36 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS05645 1da227105bae1447823caccfd116751b 553 Gene3D G3DSA:1.10.287.950 23 312 1.4E-6 T 29-03-2018 CB4_RS05645 1da227105bae1447823caccfd116751b 553 Gene3D G3DSA:1.10.287.950 313 553 3.1E-41 T 29-03-2018 CB4_RS05645 1da227105bae1447823caccfd116751b 553 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 329 478 2.4E-30 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS17460 a0f8ae28a4b1f88015630c53823ef727 189 Pfam PF05067 Manganese containing catalase 2 183 1.5E-71 T 29-03-2018 IPR007760 Manganese catalase CB4_RS17460 a0f8ae28a4b1f88015630c53823ef727 189 Gene3D G3DSA:1.20.1260.10 1 184 2.6E-49 T 29-03-2018 IPR012347 Ferritin-related CB4_RS17460 a0f8ae28a4b1f88015630c53823ef727 189 SUPERFAMILY SSF47240 2 186 1.45E-64 T 29-03-2018 IPR009078 Ferritin-like superfamily CB4_RS15990 bf5511a2cecbb60347682be5e18e99b8 375 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 259 4.4E-63 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CB4_RS15990 bf5511a2cecbb60347682be5e18e99b8 375 Gene3D G3DSA:3.40.710.10 24 303 1.2E-52 T 29-03-2018 CB4_RS15990 bf5511a2cecbb60347682be5e18e99b8 375 SUPERFAMILY SSF56601 9 276 3.31E-68 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS15990 bf5511a2cecbb60347682be5e18e99b8 375 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 113 130 5.8E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS15990 bf5511a2cecbb60347682be5e18e99b8 375 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 5.8E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS15990 bf5511a2cecbb60347682be5e18e99b8 375 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 140 153 5.8E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CB4_RS00475 67d893094b27ba32ee08486ddacfff08 304 Pfam PF00892 EamA-like transporter family 161 287 4.5E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS00475 67d893094b27ba32ee08486ddacfff08 304 Pfam PF00892 EamA-like transporter family 14 147 1.1E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS00475 67d893094b27ba32ee08486ddacfff08 304 SUPERFAMILY SSF103481 50 150 7.06E-16 T 29-03-2018 CB4_RS00475 67d893094b27ba32ee08486ddacfff08 304 SUPERFAMILY SSF103481 202 289 9.68E-11 T 29-03-2018 CB4_RS02760 c64466b0499528de2dff05c0c8e3116b 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS02760 c64466b0499528de2dff05c0c8e3116b 283 SUPERFAMILY SSF51735 1 185 4.06E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS02760 c64466b0499528de2dff05c0c8e3116b 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 183 4.9E-67 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS02760 c64466b0499528de2dff05c0c8e3116b 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 8.2E-37 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CB4_RS02760 c64466b0499528de2dff05c0c8e3116b 283 SUPERFAMILY SSF48179 185 283 5.02E-35 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CB4_RS02760 c64466b0499528de2dff05c0c8e3116b 283 PIRSF PIRSF000105 1 283 3.2E-93 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CB4_RS02760 c64466b0499528de2dff05c0c8e3116b 283 Gene3D G3DSA:3.40.50.720 2 185 5.1E-56 T 29-03-2018 CB4_RS02760 c64466b0499528de2dff05c0c8e3116b 283 Gene3D G3DSA:1.10.1040.10 186 283 1.0E-35 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CB4_RS20715 ce45037e67748543325de953b454c930 115 Gene3D G3DSA:3.30.750.24 3 111 1.7E-15 T 29-03-2018 IPR002645 STAS domain CB4_RS20715 ce45037e67748543325de953b454c930 115 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 5 102 1.1E-15 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CB4_RS20715 ce45037e67748543325de953b454c930 115 Pfam PF01740 STAS domain 3 104 8.2E-13 T 29-03-2018 IPR002645 STAS domain CB4_RS20715 ce45037e67748543325de953b454c930 115 SUPERFAMILY SSF52091 4 108 2.35E-18 T 29-03-2018 IPR002645 STAS domain CB4_RS16915 549fff9f951c7d5b50a203615f3b5c4e 451 Gene3D G3DSA:1.10.150.130 29 157 3.7E-7 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CB4_RS16915 549fff9f951c7d5b50a203615f3b5c4e 451 SUPERFAMILY SSF56349 216 393 1.77E-17 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS16915 549fff9f951c7d5b50a203615f3b5c4e 451 Gene3D G3DSA:1.10.443.10 204 399 3.6E-20 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS16915 549fff9f951c7d5b50a203615f3b5c4e 451 Pfam PF00589 Phage integrase family 218 358 7.3E-10 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS13360 549fff9f951c7d5b50a203615f3b5c4e 451 Gene3D G3DSA:1.10.150.130 29 157 3.7E-7 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CB4_RS13360 549fff9f951c7d5b50a203615f3b5c4e 451 SUPERFAMILY SSF56349 216 393 1.77E-17 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS13360 549fff9f951c7d5b50a203615f3b5c4e 451 Gene3D G3DSA:1.10.443.10 204 399 3.6E-20 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS13360 549fff9f951c7d5b50a203615f3b5c4e 451 Pfam PF00589 Phage integrase family 218 358 7.3E-10 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS06620 5a393992c1754d450efee72580dbb3fa 411 Pfam PF13490 Putative zinc-finger 12 45 2.4E-6 T 29-03-2018 IPR027383 Putative zinc-finger CB4_RS18405 515d4d6c6d5b8232c453ffbfa51a37e1 134 Pfam PF04186 FxsA cytoplasmic membrane protein 8 115 6.3E-35 T 29-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CB4_RS06570 52240853dc33f03873f672a07cb2b8f0 335 Gene3D G3DSA:3.40.50.2300 40 163 2.4E-20 T 29-03-2018 CB4_RS06570 52240853dc33f03873f672a07cb2b8f0 335 SUPERFAMILY SSF53822 48 301 7.35E-15 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS06570 52240853dc33f03873f672a07cb2b8f0 335 Pfam PF04392 ABC transporter substrate binding protein 43 334 7.2E-100 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein CB4_RS06570 52240853dc33f03873f672a07cb2b8f0 335 Gene3D G3DSA:3.40.50.2300 164 301 2.7E-22 T 29-03-2018 CB4_RS16960 47ce4faa00844f773509f5ef819dcc12 66 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS16960 47ce4faa00844f773509f5ef819dcc12 66 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 7.1E-24 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CB4_RS16960 47ce4faa00844f773509f5ef819dcc12 66 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS07405 49e651e67b7fb40d31bc18393c9366b2 66 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS07405 49e651e67b7fb40d31bc18393c9366b2 66 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 2.9E-25 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CB4_RS07405 49e651e67b7fb40d31bc18393c9366b2 66 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS17570 31648eb74e4fcb9f1d7506a4588d808f 152 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 96 1.0E-9 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CB4_RS17570 31648eb74e4fcb9f1d7506a4588d808f 152 SUPERFAMILY SSF50475 11 97 8.37E-12 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS17570 31648eb74e4fcb9f1d7506a4588d808f 152 Gene3D G3DSA:2.30.110.10 2 152 1.7E-21 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS09140 a555f1f91a5b49fa9a3ef1cb963fd756 79 Pfam PF06289 Flagellar protein (FlbD) 1 58 8.8E-25 T 29-03-2018 IPR009384 Flagellar CB4_RS10515 04bbbcdcda452d9b86b12c88e5b855d9 107 Gene3D G3DSA:3.40.190.10 1 99 3.6E-6 T 29-03-2018 CB4_RS04620 936e9b1c9e9f1a14ddbd5e70ab71355c 157 Pfam PF00583 Acetyltransferase (GNAT) family 63 141 1.3E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS04620 936e9b1c9e9f1a14ddbd5e70ab71355c 157 Gene3D G3DSA:3.40.630.30 3 156 5.1E-19 T 29-03-2018 CB4_RS04620 936e9b1c9e9f1a14ddbd5e70ab71355c 157 SUPERFAMILY SSF55729 6 149 3.95E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS10915 736a3ef3b706192074551011ec68fe64 260 Pfam PF05675 Protein of unknown function (DUF817) 6 240 2.4E-103 T 29-03-2018 IPR008535 Protein of unknown function DUF817 CB4_RS10915 736a3ef3b706192074551011ec68fe64 260 PIRSF PIRSF009141 1 260 1.4E-118 T 29-03-2018 IPR008535 Protein of unknown function DUF817 CB4_RS11795 c9ad5102cbb21f660cb06f51ec193969 63 SUPERFAMILY SSF47413 3 60 3.03E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS11795 c9ad5102cbb21f660cb06f51ec193969 63 Gene3D G3DSA:1.10.260.40 3 63 2.6E-9 T 29-03-2018 CB4_RS11795 c9ad5102cbb21f660cb06f51ec193969 63 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 1 59 1.1E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS04130 fad8fe66ffcbe19ef687b164ae0aa83a 351 Pfam PF01966 HD domain 128 235 1.9E-11 T 29-03-2018 IPR006674 HD domain CB4_RS04130 fad8fe66ffcbe19ef687b164ae0aa83a 351 SUPERFAMILY SSF109604 121 278 4.71E-23 T 29-03-2018 CB4_RS04130 fad8fe66ffcbe19ef687b164ae0aa83a 351 Gene3D G3DSA:1.10.3210.10 108 292 6.4E-29 T 29-03-2018 CB4_RS04130 fad8fe66ffcbe19ef687b164ae0aa83a 351 SMART SM00471 123 251 2.2E-4 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS10135 8babd333976208ad8fc936e38ed41208 277 SUPERFAMILY SSF53649 2 256 9.65E-37 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CB4_RS10135 8babd333976208ad8fc936e38ed41208 277 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 211 5.5E-10 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CB4_RS10135 8babd333976208ad8fc936e38ed41208 277 Gene3D G3DSA:3.40.720.10 2 262 3.3E-34 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CB4_RS12470 a46c1be842bb2683c40e8d136265296b 444 Pfam PF01098 Cell cycle protein 97 438 4.4E-43 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CB4_RS13555 fa699d9f7340233df11027754abd598d 104 SUPERFAMILY SSF103481 5 101 1.96E-13 T 29-03-2018 CB4_RS13555 fa699d9f7340233df11027754abd598d 104 Pfam PF00893 Small Multidrug Resistance protein 2 92 5.7E-21 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CB4_RS00580 663d4de1b4f3fead315675f619020d3c 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 3.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00580 663d4de1b4f3fead315675f619020d3c 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 132 3.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00580 663d4de1b4f3fead315675f619020d3c 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 112 3.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00580 663d4de1b4f3fead315675f619020d3c 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 146 166 3.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00580 663d4de1b4f3fead315675f619020d3c 181 SMART SM00347 55 156 2.9E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00580 663d4de1b4f3fead315675f619020d3c 181 SUPERFAMILY SSF46785 30 169 1.22E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00580 663d4de1b4f3fead315675f619020d3c 181 ProSitePatterns PS01117 MarR-type HTH domain signature. 95 129 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CB4_RS00580 663d4de1b4f3fead315675f619020d3c 181 Gene3D G3DSA:1.10.10.10 6 177 4.0E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00580 663d4de1b4f3fead315675f619020d3c 181 Pfam PF12802 MarR family 61 120 3.5E-13 T 29-03-2018 CB4_RS00465 fd8f6141dd3a06d45c6bbcf575e8ad36 261 Pfam PF04536 TPM domain 42 164 5.6E-35 T 29-03-2018 IPR007621 TPM domain CB4_RS17220 f5efe6db902aa59803d1cdc93678327d 220 Pfam PF09335 SNARE associated Golgi protein 64 181 1.9E-26 T 29-03-2018 IPR032816 SNARE associated Golgi protein CB4_RS12610 fed252701110ffeca414765673ade35e 165 SUPERFAMILY SSF55961 2 163 1.12E-40 T 29-03-2018 CB4_RS12610 fed252701110ffeca414765673ade35e 165 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 161 4.0E-28 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CB4_RS12610 fed252701110ffeca414765673ade35e 165 Gene3D G3DSA:3.30.530.20 2 165 4.9E-28 T 29-03-2018 IPR023393 START-like domain CB4_RS00455 129f62e5b6d3a392d0c2a3852b340ac2 468 Pfam PF00324 Amino acid permease 17 449 1.2E-115 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CB4_RS00455 129f62e5b6d3a392d0c2a3852b340ac2 468 ProSitePatterns PS00218 Amino acid permeases signature. 42 72 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CB4_RS00455 129f62e5b6d3a392d0c2a3852b340ac2 468 PIRSF PIRSF006060 1 458 8.4E-77 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS18270 ceef05d562e6c9f992edf6f13f86a0a3 69 Gene3D G3DSA:3.90.330.10 4 68 8.5E-5 T 29-03-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CB4_RS15765 c36e8261bed2684957a95e08ae73db44 46 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 3 40 1.5E-13 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CB4_RS15765 c36e8261bed2684957a95e08ae73db44 46 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 19 33 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS08995 87159dd007b39b8b4fcec5890a859f60 242 Gene3D G3DSA:3.30.70.1230 52 239 4.0E-20 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CB4_RS08995 87159dd007b39b8b4fcec5890a859f60 242 SUPERFAMILY SSF55073 56 223 4.08E-25 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS08995 87159dd007b39b8b4fcec5890a859f60 242 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 57 223 6.9E-9 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CB4_RS07320 2bb47a0638826e06a2eb3e3c65fe82e1 281 SUPERFAMILY SSF52540 4 234 8.34E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07320 2bb47a0638826e06a2eb3e3c65fe82e1 281 Pfam PF00005 ABC transporter 25 170 1.5E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS07320 2bb47a0638826e06a2eb3e3c65fe82e1 281 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS07320 2bb47a0638826e06a2eb3e3c65fe82e1 281 Gene3D G3DSA:3.40.50.300 1 279 1.3E-65 T 29-03-2018 CB4_RS07320 2bb47a0638826e06a2eb3e3c65fe82e1 281 SMART SM00382 31 218 3.9E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS07320 2bb47a0638826e06a2eb3e3c65fe82e1 281 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 18 204 6.4E-67 T 29-03-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 CB4_RS08815 a65600347a3ac5e961616ce8a57069a6 334 Gene3D G3DSA:1.10.10.10 22 99 6.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS06580 3eccc0f8ceaef3770600011132010c9e 82 Pfam PF10752 Protein of unknown function (DUF2533) 1 78 4.9E-23 T 29-03-2018 IPR019688 Protein of unknown function DUF2533 CB4_RS08855 4c4ed19b376bbd44bdfceaf854eef199 220 SUPERFAMILY SSF46894 165 205 5.1E-7 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CB4_RS08855 4c4ed19b376bbd44bdfceaf854eef199 220 Gene3D G3DSA:1.10.10.10 141 207 1.7E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS08855 4c4ed19b376bbd44bdfceaf854eef199 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 204 7.3E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CB4_RS02695 a990f86d208137b2d17a3ccadc99795d 140 PRINTS PR01438 Universal stress protein signature 100 112 4.0E-19 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS02695 a990f86d208137b2d17a3ccadc99795d 140 PRINTS PR01438 Universal stress protein signature 118 140 4.0E-19 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS02695 a990f86d208137b2d17a3ccadc99795d 140 PRINTS PR01438 Universal stress protein signature 4 22 4.0E-19 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS02695 a990f86d208137b2d17a3ccadc99795d 140 Gene3D G3DSA:3.40.50.620 1 140 3.8E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS02695 a990f86d208137b2d17a3ccadc99795d 140 Pfam PF00582 Universal stress protein family 3 140 1.3E-31 T 29-03-2018 IPR006016 UspA GO:0006950 CB4_RS02695 a990f86d208137b2d17a3ccadc99795d 140 SUPERFAMILY SSF52402 3 140 1.59E-33 T 29-03-2018 CB4_RS02695 a990f86d208137b2d17a3ccadc99795d 140 PIRSF PIRSF006276 1 140 4.5E-18 T 29-03-2018 IPR006015 Universal stress protein A CB4_RS14485 8890ff6ed54b47d5cba55fd74d26772c 57 SUPERFAMILY SSF140500 3 54 3.14E-14 T 29-03-2018 CB4_RS14485 8890ff6ed54b47d5cba55fd74d26772c 57 Pfam PF09388 Spo0E like sporulation regulatory protein 7 48 4.3E-18 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CB4_RS11010 85d3627baf3643bcdd5c76c87e5509a5 189 Gene3D G3DSA:3.10.450.100 34 179 0.0049 T 29-03-2018 CB4_RS11010 85d3627baf3643bcdd5c76c87e5509a5 189 Pfam PF12870 Domain of unknown function (DUF4878) 33 111 4.8E-6 T 29-03-2018 IPR024267 Domain of unknown function (DUF4878) CB4_RS13045 b2e02882b546029d27247018a3ea8064 499 SUPERFAMILY SSF52540 281 497 3.96E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS13045 b2e02882b546029d27247018a3ea8064 499 SMART SM00487 370 498 0.0011 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS13045 b2e02882b546029d27247018a3ea8064 499 Gene3D G3DSA:3.40.50.300 358 499 3.2E-22 T 29-03-2018 CB4_RS13045 b2e02882b546029d27247018a3ea8064 499 Pfam PF04851 Type III restriction enzyme, res subunit 373 496 3.3E-13 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CB4_RS12355 725e622d10e7804fc8a058a4a36c3978 290 Pfam PF06207 Protein of unknown function (DUF1002) 33 252 3.6E-74 T 29-03-2018 IPR009343 Protein of unknown function DUF1002 CB4_RS09655 66b6666ce99e4ea72d73c7c91ad7198f 389 Gene3D G3DSA:3.40.50.150 97 371 1.2E-63 T 29-03-2018 CB4_RS09655 66b6666ce99e4ea72d73c7c91ad7198f 389 SUPERFAMILY SSF53335 108 372 9.05E-79 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS09655 66b6666ce99e4ea72d73c7c91ad7198f 389 PIRSF PIRSF003085 4 387 5.9E-127 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CB4_RS09655 66b6666ce99e4ea72d73c7c91ad7198f 389 Pfam PF02353 Mycolic acid cyclopropane synthetase 100 367 1.2E-102 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS06895 079996f562991fd280c75a3b20b7521c 177 Pfam PF14568 SMI1-KNR4 cell-wall 23 138 3.5E-10 T 29-03-2018 CB4_RS06895 079996f562991fd280c75a3b20b7521c 177 SMART SM00860 17 149 0.0054 T 29-03-2018 IPR018958 Knr4/Smi1-like domain CB4_RS06895 079996f562991fd280c75a3b20b7521c 177 Gene3D G3DSA:3.40.1580.10 11 160 1.8E-13 T 29-03-2018 CB4_RS06895 079996f562991fd280c75a3b20b7521c 177 SUPERFAMILY SSF160631 9 163 4.58E-12 T 29-03-2018 CB4_RS15185 8ed4f0de88e36da7b8efba2fd58ec819 289 Gene3D G3DSA:1.10.600.10 20 185 0.001 T 29-03-2018 IPR008949 Isoprenoid synthase domain CB4_RS15185 8ed4f0de88e36da7b8efba2fd58ec819 289 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 47 237 2.0E-41 T 29-03-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 CB4_RS02885 acec4d4ef126e31e0ee1f638382dcc0f 247 Pfam PF02535 ZIP Zinc transporter 98 218 2.3E-15 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CB4_RS02655 114d56f3b7bc1eacc21cc93ab9a8cd29 404 PIRSF PIRSF037259 1 404 3.2E-86 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CB4_RS02655 114d56f3b7bc1eacc21cc93ab9a8cd29 404 Pfam PF05975 Bacterial ABC transporter protein EcsB 4 382 1.0E-92 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CB4_RS07415 dd82c0f5382c0935801bb85c357945df 247 SUPERFAMILY SSF52540 49 242 4.07E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07415 dd82c0f5382c0935801bb85c357945df 247 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 21 243 8.8E-90 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related CB4_RS07415 dd82c0f5382c0935801bb85c357945df 247 Gene3D G3DSA:3.40.50.300 2 247 3.4E-91 T 29-03-2018 CB4_RS07415 dd82c0f5382c0935801bb85c357945df 247 PIRSF PIRSF028756 2 247 9.5E-81 T 29-03-2018 IPR016898 Polyphosphate kinase 2 CB4_RS10960 1920163ad758d55c2eb6f4e7208c3e2a 431 PRINTS PR00758 Arsenical pump membrane protein signature 219 244 1.8E-112 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS10960 1920163ad758d55c2eb6f4e7208c3e2a 431 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 1.8E-112 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS10960 1920163ad758d55c2eb6f4e7208c3e2a 431 PRINTS PR00758 Arsenical pump membrane protein signature 179 202 1.8E-112 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS10960 1920163ad758d55c2eb6f4e7208c3e2a 431 PRINTS PR00758 Arsenical pump membrane protein signature 280 304 1.8E-112 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS10960 1920163ad758d55c2eb6f4e7208c3e2a 431 PRINTS PR00758 Arsenical pump membrane protein signature 399 423 1.8E-112 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS10960 1920163ad758d55c2eb6f4e7208c3e2a 431 PRINTS PR00758 Arsenical pump membrane protein signature 146 170 1.8E-112 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS10960 1920163ad758d55c2eb6f4e7208c3e2a 431 PRINTS PR00758 Arsenical pump membrane protein signature 325 347 1.8E-112 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS10960 1920163ad758d55c2eb6f4e7208c3e2a 431 PRINTS PR00758 Arsenical pump membrane protein signature 366 391 1.8E-112 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS10960 1920163ad758d55c2eb6f4e7208c3e2a 431 Pfam PF02040 Arsenical pump membrane protein 6 427 2.2E-213 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS10960 1920163ad758d55c2eb6f4e7208c3e2a 431 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 5 429 4.9E-224 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CB4_RS08695 09e2097824f71b7027ca16dedf62539b 185 SUPERFAMILY SSF51306 33 185 1.57E-53 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CB4_RS08695 09e2097824f71b7027ca16dedf62539b 185 ProSitePatterns PS00501 Signal peptidases I serine active site. 44 51 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CB4_RS08695 09e2097824f71b7027ca16dedf62539b 185 ProSitePatterns PS00761 Signal peptidases I signature 3. 144 157 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CB4_RS08695 09e2097824f71b7027ca16dedf62539b 185 Pfam PF00717 Peptidase S24-like 42 109 1.8E-19 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CB4_RS08695 09e2097824f71b7027ca16dedf62539b 185 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 18 179 2.5E-55 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS08695 09e2097824f71b7027ca16dedf62539b 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 139 158 1.3E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS08695 09e2097824f71b7027ca16dedf62539b 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 85 97 1.3E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS08695 09e2097824f71b7027ca16dedf62539b 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 35 51 1.3E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CB4_RS08695 09e2097824f71b7027ca16dedf62539b 185 Gene3D G3DSA:2.10.109.10 31 184 9.1E-49 T 29-03-2018 CB4_RS18300 f35c82b6c4654cc1ebfd35d279753329 81 Pfam PF10055 Uncharacterized small protein (DUF2292) 39 74 6.4E-19 T 29-03-2018 IPR018743 Protein of unknown function DUF2292 CB4_RS00460 b0f51ce5c1c86e8ca7178dad665ac0ad 354 SMART SM00471 134 270 1.4E-10 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS00460 b0f51ce5c1c86e8ca7178dad665ac0ad 354 Gene3D G3DSA:1.10.3210.10 53 309 1.7E-40 T 29-03-2018 CB4_RS00460 b0f51ce5c1c86e8ca7178dad665ac0ad 354 SUPERFAMILY SSF109604 125 285 2.66E-34 T 29-03-2018 CB4_RS00460 b0f51ce5c1c86e8ca7178dad665ac0ad 354 Pfam PF01966 HD domain 138 260 3.2E-16 T 29-03-2018 IPR006674 HD domain CB4_RS10085 45af157c08d574f37566895a788207e2 223 SUPERFAMILY SSF52540 4 222 1.09E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS10085 45af157c08d574f37566895a788207e2 223 Gene3D G3DSA:3.40.50.300 1 223 3.4E-62 T 29-03-2018 CB4_RS10085 45af157c08d574f37566895a788207e2 223 Pfam PF00005 ABC transporter 24 172 4.3E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS10085 45af157c08d574f37566895a788207e2 223 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS10085 45af157c08d574f37566895a788207e2 223 SMART SM00382 33 220 2.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS06890 591e492775e51473675136050ad92a14 388 Pfam PF14107 Domain of unknown function (DUF4280) 16 116 4.0E-19 T 29-03-2018 IPR025460 Protein of unknown function DUF4280 CB4_RS06890 591e492775e51473675136050ad92a14 388 Pfam PF13930 DNA/RNA non-specific endonuclease 255 373 6.1E-20 T 29-03-2018 CB4_RS14385 5668b104b6b7420038680df8996ff803 314 Pfam PF13280 WYL domain 140 310 4.5E-38 T 29-03-2018 IPR026881 WYL domain CB4_RS14385 5668b104b6b7420038680df8996ff803 314 SUPERFAMILY SSF46785 3 60 1.47E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14385 5668b104b6b7420038680df8996ff803 314 Gene3D G3DSA:1.10.10.10 1 63 5.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS14385 5668b104b6b7420038680df8996ff803 314 Pfam PF08279 HTH domain 6 58 6.7E-11 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CB4_RS14385 5668b104b6b7420038680df8996ff803 314 PIRSF PIRSF016838 1 314 2.7E-20 T 29-03-2018 IPR028349 Protein PafC CB4_RS01260 cdf662d37950140449a44728206fca8e 355 SUPERFAMILY SSF55931 4 269 5.61E-87 T 29-03-2018 CB4_RS01260 cdf662d37950140449a44728206fca8e 355 ProSitePatterns PS00112 Phosphagen kinase active site signature. 168 174 - T 29-03-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 CB4_RS01260 cdf662d37950140449a44728206fca8e 355 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 351 37.335 T 29-03-2018 IPR023660 Protein arginine kinase GO:0006950|GO:0016775 CB4_RS01260 cdf662d37950140449a44728206fca8e 355 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 56 254 6.5E-75 T 29-03-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 CB4_RS01260 cdf662d37950140449a44728206fca8e 355 Gene3D G3DSA:3.30.590.10 6 256 3.5E-87 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CB4_RS13570 9d84f6327730466c68d9e3937a0dc5fe 254 Gene3D G3DSA:3.40.50.1820 11 248 3.5E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS13570 9d84f6327730466c68d9e3937a0dc5fe 254 SUPERFAMILY SSF53474 20 225 1.04E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS13570 9d84f6327730466c68d9e3937a0dc5fe 254 Pfam PF00326 Prolyl oligopeptidase family 69 242 4.8E-7 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CB4_RS16070 faf4521f5df2244a17a93b10af4c8168 439 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 3 418 6.8E-156 T 29-03-2018 IPR021228 Protein of unknown function DUF2791 CB4_RS18370 ebc5095e9acf24024f19d4dc8d9aac87 275 SUPERFAMILY SSF117892 66 200 9.68E-17 T 29-03-2018 IPR001107 Band 7 domain CB4_RS18370 ebc5095e9acf24024f19d4dc8d9aac87 275 PRINTS PR00679 Prohibitin signature 119 137 6.6E-22 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 CB4_RS18370 ebc5095e9acf24024f19d4dc8d9aac87 275 PRINTS PR00679 Prohibitin signature 190 213 6.6E-22 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 CB4_RS18370 ebc5095e9acf24024f19d4dc8d9aac87 275 PRINTS PR00679 Prohibitin signature 78 94 6.6E-22 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 CB4_RS18370 ebc5095e9acf24024f19d4dc8d9aac87 275 PRINTS PR00679 Prohibitin signature 142 158 6.6E-22 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 CB4_RS18370 ebc5095e9acf24024f19d4dc8d9aac87 275 PRINTS PR00679 Prohibitin signature 165 184 6.6E-22 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 CB4_RS18370 ebc5095e9acf24024f19d4dc8d9aac87 275 PRINTS PR00679 Prohibitin signature 213 229 6.6E-22 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 CB4_RS18370 ebc5095e9acf24024f19d4dc8d9aac87 275 SMART SM00244 34 195 1.6E-27 T 29-03-2018 IPR001107 Band 7 domain CB4_RS18370 ebc5095e9acf24024f19d4dc8d9aac87 275 Pfam PF01145 SPFH domain / Band 7 family 38 221 1.2E-32 T 29-03-2018 IPR001107 Band 7 domain CB4_RS14305 5b3b6b0c8bee1d01882084aeec7a2b1d 104 SUPERFAMILY SSF103481 4 102 7.72E-10 T 29-03-2018 CB4_RS14305 5b3b6b0c8bee1d01882084aeec7a2b1d 104 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 2 104 5.6E-44 T 29-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CB4_RS14305 5b3b6b0c8bee1d01882084aeec7a2b1d 104 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 1 103 21.259 T 29-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CB4_RS02685 76eb1c3dc6d77b86a5b68165f216587d 111 Pfam PF13045 Protein of unknown function (DUF3905) 12 88 1.3E-37 T 29-03-2018 IPR024999 Protein of unknown function DUF3905 CB4_RS00050 0a073088f12db986098b068d30391610 145 Gene3D G3DSA:1.10.10.10 2 143 2.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00050 0a073088f12db986098b068d30391610 145 SUPERFAMILY SSF46785 8 142 1.39E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS00050 0a073088f12db986098b068d30391610 145 SMART SM00347 24 125 3.7E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00050 0a073088f12db986098b068d30391610 145 Pfam PF01047 MarR family 31 88 2.5E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00050 0a073088f12db986098b068d30391610 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 4.6E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00050 0a073088f12db986098b068d30391610 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 4.6E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00050 0a073088f12db986098b068d30391610 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 4.6E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS00050 0a073088f12db986098b068d30391610 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 4.6E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS07500 aaa31be3e8679a1c8b96a97298587f4d 150 Gene3D G3DSA:3.10.129.10 1 149 3.7E-47 T 29-03-2018 CB4_RS07500 aaa31be3e8679a1c8b96a97298587f4d 150 SUPERFAMILY SSF54637 4 141 3.27E-44 T 29-03-2018 IPR029069 HotDog domain CB4_RS07500 aaa31be3e8679a1c8b96a97298587f4d 150 Pfam PF03061 Thioesterase superfamily 13 85 4.9E-18 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS03420 dab36ea80d79217837df6e110881e627 151 Gene3D G3DSA:2.30.290.10 3 148 1.7E-45 T 29-03-2018 IPR024046 Flagellar assembly factor FliW domain CB4_RS03420 dab36ea80d79217837df6e110881e627 151 Pfam PF02623 FliW protein 22 138 4.2E-35 T 29-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CB4_RS03420 dab36ea80d79217837df6e110881e627 151 SUPERFAMILY SSF141457 4 140 1.11E-40 T 29-03-2018 IPR024046 Flagellar assembly factor FliW domain CB4_RS03420 dab36ea80d79217837df6e110881e627 151 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 19 141 23.263 T 29-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CB4_RS09380 03a052e5a4aed0f4b413fc7a00041806 228 SUPERFAMILY SSF56300 115 221 5.17E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS09380 03a052e5a4aed0f4b413fc7a00041806 228 SUPERFAMILY SSF56300 1 77 5.17E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS09380 03a052e5a4aed0f4b413fc7a00041806 228 Gene3D G3DSA:3.60.21.10 1 227 6.1E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CB4_RS09380 03a052e5a4aed0f4b413fc7a00041806 228 Pfam PF00149 Calcineurin-like phosphoesterase 1 193 1.1E-14 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CB4_RS07900 fa4f827df71aedcb5080d4dbd5a33941 67 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 3.8E-16 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CB4_RS07900 fa4f827df71aedcb5080d4dbd5a33941 67 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 4 66 4.0E-30 T 29-03-2018 IPR009570 Stage III sporulation protein AC CB4_RS10805 916b94d995a2acfc8dd4d6bc9d765c3b 112 Pfam PF02635 DsrE/DsrF-like family 40 110 9.3E-8 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein CB4_RS10805 916b94d995a2acfc8dd4d6bc9d765c3b 112 SUPERFAMILY SSF75169 13 105 1.31E-15 T 29-03-2018 IPR027396 DsrEFH-like CB4_RS10805 916b94d995a2acfc8dd4d6bc9d765c3b 112 Gene3D G3DSA:3.40.1260.10 1 111 6.7E-17 T 29-03-2018 CB4_RS03000 bed2632014077585f64838bfc2b3b3f1 179 Gene3D G3DSA:3.40.50.700 26 179 4.9E-46 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03000 bed2632014077585f64838bfc2b3b3f1 179 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 16 167 42.057 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03000 bed2632014077585f64838bfc2b3b3f1 179 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 77 162 2.2E-23 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03000 bed2632014077585f64838bfc2b3b3f1 179 SUPERFAMILY SSF56770 25 170 8.11E-65 T 29-03-2018 CB4_RS03000 bed2632014077585f64838bfc2b3b3f1 179 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 27 168 1.5E-70 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS10260 02cf0898c9d804065d79ab5523249861 80 Pfam PF14035 YlzJ-like protein 4 67 4.6E-23 T 29-03-2018 IPR025619 YlzJ-like protein CB4_RS06925 7fdc73edc7584c5a36fb41285ada412c 150 Pfam PF14433 SUKH-3 immunity protein 1 139 5.7E-23 T 29-03-2018 IPR025850 SUKH-3 immunity protein CB4_RS20490 51bd6a48dc51c12952ba3ce748cbe810 143 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 5 136 4.8E-44 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CB4_RS20490 51bd6a48dc51c12952ba3ce748cbe810 143 Gene3D G3DSA:3.40.630.30 1 143 2.5E-33 T 29-03-2018 CB4_RS20490 51bd6a48dc51c12952ba3ce748cbe810 143 SUPERFAMILY SSF55729 9 141 1.15E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS20490 51bd6a48dc51c12952ba3ce748cbe810 143 Pfam PF00583 Acetyltransferase (GNAT) family 12 116 1.4E-19 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS11995 bd3ade47d62f3c6b72c727c64c5c21de 441 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CB4_RS11995 bd3ade47d62f3c6b72c727c64c5c21de 441 PIRSF PIRSF006060 1 441 4.8E-69 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS11995 bd3ade47d62f3c6b72c727c64c5c21de 441 Pfam PF00324 Amino acid permease 14 410 3.4E-89 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CB4_RS11775 8de49cd157ad97cb31f84eccb68b67fd 300 Pfam PF13676 TIR domain 21 128 1.0E-7 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CB4_RS11775 8de49cd157ad97cb31f84eccb68b67fd 300 SUPERFAMILY SSF52200 10 98 4.19E-7 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CB4_RS11775 8de49cd157ad97cb31f84eccb68b67fd 300 Gene3D G3DSA:3.40.50.10140 10 176 2.5E-12 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CB4_RS10675 7c54b92325d88c73c93ad587dc7d4f0d 195 Gene3D G3DSA:2.20.110.10 34 154 0.01 T 29-03-2018 CB4_RS19490 8cd836c5cafbf6b0c2c60a072b7760c2 243 SUPERFAMILY SSF53448 3 209 1.33E-41 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS19490 8cd836c5cafbf6b0c2c60a072b7760c2 243 Pfam PF00535 Glycosyl transferase family 2 6 164 2.1E-30 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CB4_RS19490 8cd836c5cafbf6b0c2c60a072b7760c2 243 Gene3D G3DSA:3.90.550.10 2 233 2.8E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS13395 736ec81b772fed4dc0a67b5ab7cfd48f 81 Pfam PF10083 Uncharacterized protein conserved in bacteria (DUF2321) 1 68 5.6E-19 T 29-03-2018 IPR016891 Protein of unknown function DUF2321 CB4_RS01540 89fe822fa93100fbc51be649ab3809ad 354 SUPERFAMILY SSF50685 281 338 1.19E-11 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CB4_RS01540 89fe822fa93100fbc51be649ab3809ad 354 Gene3D G3DSA:2.40.40.10 150 348 3.0E-38 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CB4_RS01540 89fe822fa93100fbc51be649ab3809ad 354 SMART SM01208 152 230 1.6E-21 T 29-03-2018 IPR011098 G5 domain CB4_RS01540 89fe822fa93100fbc51be649ab3809ad 354 Pfam PF07501 G5 domain 155 228 3.9E-20 T 29-03-2018 IPR011098 G5 domain CB4_RS01540 89fe822fa93100fbc51be649ab3809ad 354 Pfam PF06725 3D domain 288 347 9.8E-17 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CB4_RS01540 89fe822fa93100fbc51be649ab3809ad 354 Pfam PF03990 Domain of unknown function (DUF348) 47 80 3.0E-6 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CB4_RS01540 89fe822fa93100fbc51be649ab3809ad 354 Pfam PF03990 Domain of unknown function (DUF348) 99 138 9.2E-9 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CB4_RS08500 d5ea2deb3a172882e2858f1cb7cb18ea 348 SUPERFAMILY SSF102114 88 307 1.1E-12 T 29-03-2018 CB4_RS08500 d5ea2deb3a172882e2858f1cb7cb18ea 348 Pfam PF13394 4Fe-4S single cluster domain 110 206 2.5E-5 T 29-03-2018 CB4_RS08500 d5ea2deb3a172882e2858f1cb7cb18ea 348 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 2 344 71.719 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS08500 d5ea2deb3a172882e2858f1cb7cb18ea 348 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 1 345 4.7E-147 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS08500 d5ea2deb3a172882e2858f1cb7cb18ea 348 Gene3D G3DSA:3.20.20.70 12 345 7.3E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS08500 d5ea2deb3a172882e2858f1cb7cb18ea 348 PIRSF PIRSF006004 1 348 2.4E-136 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CB4_RS08500 d5ea2deb3a172882e2858f1cb7cb18ea 348 Pfam PF04055 Radical SAM superfamily 105 275 8.3E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS13305 3bfd477c0673e8647603f8fa537eda49 73 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 28 37 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS13305 3bfd477c0673e8647603f8fa537eda49 73 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 13 67 8.3E-23 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CB4_RS13305 3bfd477c0673e8647603f8fa537eda49 73 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 46 60 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS16510 b02487a24b508b86780b6b57a78ed500 502 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 348 470 5.4E-11 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CB4_RS16510 b02487a24b508b86780b6b57a78ed500 502 PIRSF PIRSF038958 3 498 2.5E-74 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CB4_RS16510 b02487a24b508b86780b6b57a78ed500 502 Pfam PF01943 Polysaccharide biosynthesis protein 5 233 1.6E-23 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CB4_RS18480 df9dc46fcca39e5624ddb81ca04cd392 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 5.5E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS18480 df9dc46fcca39e5624ddb81ca04cd392 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 5.5E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS18480 df9dc46fcca39e5624ddb81ca04cd392 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 5.5E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS18480 df9dc46fcca39e5624ddb81ca04cd392 151 Gene3D G3DSA:1.10.10.10 2 147 4.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18480 df9dc46fcca39e5624ddb81ca04cd392 151 SUPERFAMILY SSF46785 11 147 2.01E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS18480 df9dc46fcca39e5624ddb81ca04cd392 151 SMART SM00347 33 133 3.9E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS18480 df9dc46fcca39e5624ddb81ca04cd392 151 Pfam PF01047 MarR family 40 97 4.0E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CB4_RS07725 42d667293854ab55f9df87c3ba6db875 629 SUPERFAMILY SSF51998 1 411 1.4E-110 T 29-03-2018 CB4_RS07725 42d667293854ab55f9df87c3ba6db875 629 PRINTS PR01183 Ribonucleotide reductase large chain signature 221 244 6.2E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS07725 42d667293854ab55f9df87c3ba6db875 629 PRINTS PR01183 Ribonucleotide reductase large chain signature 155 178 6.2E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS07725 42d667293854ab55f9df87c3ba6db875 629 PRINTS PR01183 Ribonucleotide reductase large chain signature 193 215 6.2E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS07725 42d667293854ab55f9df87c3ba6db875 629 PRINTS PR01183 Ribonucleotide reductase large chain signature 276 303 6.2E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS07725 42d667293854ab55f9df87c3ba6db875 629 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 1 410 3.0E-130 T 29-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CB4_RS07725 42d667293854ab55f9df87c3ba6db875 629 Pfam PF02867 Ribonucleotide reductase, barrel domain 1 400 3.3E-107 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CB4_RS07725 42d667293854ab55f9df87c3ba6db875 629 Gene3D G3DSA:3.20.70.20 1 407 1.4E-119 T 29-03-2018 CB4_RS12345 c7fbf7792d647c70ae2ee84c510c7b5c 390 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 214 381 6.2E-32 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS12345 c7fbf7792d647c70ae2ee84c510c7b5c 390 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 10 383 2.7E-87 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS15830 5281393bc048fa30ad5df8954bf2f43a 89 Gene3D G3DSA:1.20.58.70 26 88 7.2E-4 T 29-03-2018 CB4_RS18190 cf5ba0951083e1077ec0595ffe7290b0 66 Pfam PF09388 Spo0E like sporulation regulatory protein 20 61 2.4E-8 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CB4_RS18190 cf5ba0951083e1077ec0595ffe7290b0 66 SUPERFAMILY SSF140500 16 64 3.01E-8 T 29-03-2018 CB4_RS15385 5ce67ed3491b4ac71f6e037aec2894a4 273 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 70 142 2.8E-17 T 29-03-2018 CB4_RS15385 5ce67ed3491b4ac71f6e037aec2894a4 273 Gene3D G3DSA:3.30.1380.10 4 142 2.2E-29 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS15385 5ce67ed3491b4ac71f6e037aec2894a4 273 Gene3D G3DSA:3.30.457.10 245 273 9.5E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS15385 5ce67ed3491b4ac71f6e037aec2894a4 273 SUPERFAMILY SSF55166 7 142 7.85E-28 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CB4_RS05325 b2b67dd0045a7d21828ffe9f73968b2d 364 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 5 357 49.371 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CB4_RS05325 b2b67dd0045a7d21828ffe9f73968b2d 364 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 7 352 5.6E-158 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CB4_RS05325 b2b67dd0045a7d21828ffe9f73968b2d 364 SMART SM01329 6 353 1.8E-198 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CB4_RS05325 b2b67dd0045a7d21828ffe9f73968b2d 364 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CB4_RS05325 b2b67dd0045a7d21828ffe9f73968b2d 364 Gene3D G3DSA:3.40.718.10 1 361 1.1E-130 T 29-03-2018 CB4_RS05325 b2b67dd0045a7d21828ffe9f73968b2d 364 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 353 5.2E-135 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CB4_RS05325 b2b67dd0045a7d21828ffe9f73968b2d 364 SUPERFAMILY SSF53659 2 359 1.51E-122 T 29-03-2018 CB4_RS17555 2078e0c0440137775500ac2bd1496520 213 Gene3D G3DSA:1.10.530.10 71 212 3.4E-13 T 29-03-2018 CB4_RS17555 2078e0c0440137775500ac2bd1496520 213 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 84 208 1.5E-12 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CB4_RS07840 99aa4ccd3a1af96d538e2403cdfa6255 163 SUPERFAMILY SSF89963 92 163 4.97E-28 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CB4_RS07840 99aa4ccd3a1af96d538e2403cdfa6255 163 Gene3D G3DSA:3.30.70.860 99 163 7.2E-32 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain CB4_RS07840 99aa4ccd3a1af96d538e2403cdfa6255 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 27.678 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CB4_RS07840 99aa4ccd3a1af96d538e2403cdfa6255 163 Gene3D G3DSA:3.30.70.990 13 98 6.7E-32 T 29-03-2018 IPR035570 UPF0234 N-terminal domain CB4_RS07840 99aa4ccd3a1af96d538e2403cdfa6255 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 9.4E-66 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CB4_RS07840 99aa4ccd3a1af96d538e2403cdfa6255 163 SUPERFAMILY SSF89963 5 90 1.07E-29 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CB4_RS05790 bf24298556cbf5d30e450dd1e8822866 261 Pfam PF04350 Pilus assembly protein, PilO 162 233 2.8E-5 T 29-03-2018 IPR007445 Pilus assembly protein, PilO CB4_RS05790 bf24298556cbf5d30e450dd1e8822866 261 Gene3D G3DSA:3.30.70.60 75 245 2.9E-17 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CB4_RS09200 b891d7742f68aef9410e2b1891f6587d 294 SUPERFAMILY SSF52540 28 276 1.3E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09200 b891d7742f68aef9410e2b1891f6587d 294 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 29 191 2.4E-17 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CB4_RS09200 b891d7742f68aef9410e2b1891f6587d 294 Gene3D G3DSA:3.40.50.300 28 273 1.1E-48 T 29-03-2018 CB4_RS09200 b891d7742f68aef9410e2b1891f6587d 294 PIRSF PIRSF003092 1 294 1.1E-85 T 29-03-2018 IPR025501 ATP binding protein MinD CB4_RS04650 0bc9f6bc0d891c774b003c16ec004dd1 137 Pfam PF08896 Domain of unknown function (DUF1842) 8 120 2.0E-31 T 29-03-2018 IPR014992 Domain of unknown function DUF1842 CB4_RS06730 59a286ebfda6c804abdee6b2a53347bd 366 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 65 318 2.0E-82 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CB4_RS06730 59a286ebfda6c804abdee6b2a53347bd 366 PIRSF PIRSF006470 36 364 3.1E-109 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CB4_RS06730 59a286ebfda6c804abdee6b2a53347bd 366 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 65 346 2.1E-88 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CB4_RS13320 bcaa2a3b3ba581961791941dd2dc2818 131 Pfam PF09639 YjcQ protein 8 86 3.0E-5 T 29-03-2018 IPR018597 Bacteriophage Tuc2009, YjcQ CB4_RS06495 6f33718a76d1167061f08e8146c613c5 326 SUPERFAMILY SSF52518 2 204 1.71E-68 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS06495 6f33718a76d1167061f08e8146c613c5 326 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 1.8E-43 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CB4_RS06495 6f33718a76d1167061f08e8146c613c5 326 SMART SM00861 4 179 2.0E-67 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CB4_RS06495 6f33718a76d1167061f08e8146c613c5 326 Gene3D G3DSA:3.40.50.920 195 325 3.5E-36 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS06495 6f33718a76d1167061f08e8146c613c5 326 SUPERFAMILY SSF52922 189 326 1.96E-43 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CB4_RS06495 6f33718a76d1167061f08e8146c613c5 326 Gene3D G3DSA:3.40.50.970 1 194 6.8E-67 T 29-03-2018 CB4_RS06495 6f33718a76d1167061f08e8146c613c5 326 Pfam PF02780 Transketolase, C-terminal domain 194 316 3.0E-39 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CB4_RS05825 2e95857f2f55465e8fd353f762e221ec 222 Gene3D G3DSA:3.30.750.50 8 96 5.5E-25 T 29-03-2018 CB4_RS05825 2e95857f2f55465e8fd353f762e221ec 222 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 7 208 20.826 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CB4_RS05825 2e95857f2f55465e8fd353f762e221ec 222 Gene3D G3DSA:2.160.20.70 97 211 6.1E-33 T 29-03-2018 CB4_RS05825 2e95857f2f55465e8fd353f762e221ec 222 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 9 202 1.9E-35 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CB4_RS05825 2e95857f2f55465e8fd353f762e221ec 222 SUPERFAMILY SSF63848 104 207 4.05E-28 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CB4_RS05825 2e95857f2f55465e8fd353f762e221ec 222 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 106 202 5.1E-28 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CB4_RS06160 7fbc5b00fab4802cf260edb468b7b716 327 Pfam PF07070 SpoOM protein 2 195 9.8E-43 T 29-03-2018 IPR009776 Sporulation stage 0, protein M CB4_RS05940 38c7b461d2985ab15a07523a1e0eeef7 72 Pfam PF11146 Protein of unknown function (DUF2905) 5 68 2.0E-26 T 29-03-2018 IPR021320 Protein of unknown function DUF2905 CB4_RS12905 31da672d684c385c48d4ea07b9394dad 195 SUPERFAMILY SSF52218 1 191 1.71E-44 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS12905 31da672d684c385c48d4ea07b9394dad 195 Pfam PF02525 Flavodoxin-like fold 1 187 6.0E-40 T 29-03-2018 IPR003680 Flavodoxin-like fold CB4_RS12905 31da672d684c385c48d4ea07b9394dad 195 Gene3D G3DSA:3.40.50.360 1 193 2.2E-37 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS03290 3c6a4cecb35c6c92b322d7ce89c29672 167 Pfam PF06338 ComK protein 67 160 2.8E-5 T 29-03-2018 IPR010461 Competence protein ComK GO:0030420 CB4_RS01240 4f7b60c810739bb2016ac2022e8dd7a8 242 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 11 170 1.1E-41 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CB4_RS01240 4f7b60c810739bb2016ac2022e8dd7a8 242 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 72 2.8E-15 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CB4_RS01240 4f7b60c810739bb2016ac2022e8dd7a8 242 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 50 72 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CB4_RS16175 995de4848f59038c1522a42806854eaa 117 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 4 112 8.1E-41 T 29-03-2018 IPR005562 SpoVA CB4_RS16175 995de4848f59038c1522a42806854eaa 117 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 5 117 1.6E-49 T 29-03-2018 IPR014204 Sporulation stage V, protein AE CB4_RS06000 752493ca316be540fc0fdc43801dcaaf 171 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 171 1.2E-68 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CB4_RS06000 752493ca316be540fc0fdc43801dcaaf 171 Gene3D G3DSA:3.40.50.2020 1 170 4.9E-38 T 29-03-2018 CB4_RS06000 752493ca316be540fc0fdc43801dcaaf 171 SUPERFAMILY SSF53271 3 161 2.13E-49 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CB4_RS06000 752493ca316be540fc0fdc43801dcaaf 171 Pfam PF00156 Phosphoribosyl transferase domain 27 160 8.4E-19 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CB4_RS06000 752493ca316be540fc0fdc43801dcaaf 171 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 171 37.282 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CB4_RS10120 83f3688d63beda3340186131b4f7897d 230 SUPERFAMILY SSF56112 36 168 2.81E-13 T 29-03-2018 IPR011009 Protein kinase-like domain CB4_RS10120 83f3688d63beda3340186131b4f7897d 230 Gene3D G3DSA:1.10.510.10 31 203 2.1E-7 T 29-03-2018 CB4_RS00375 e21f008cfaf1705d19283b4cb84c1cd1 263 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CB4_RS00375 e21f008cfaf1705d19283b4cb84c1cd1 263 Gene3D G3DSA:3.90.226.10 11 221 2.1E-58 T 29-03-2018 CB4_RS00375 e21f008cfaf1705d19283b4cb84c1cd1 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 262 6.4E-45 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CB4_RS00375 e21f008cfaf1705d19283b4cb84c1cd1 263 Gene3D G3DSA:1.10.12.10 249 262 3.6E-4 T 29-03-2018 IPR014748 Crontonase, C-terminal CB4_RS00375 e21f008cfaf1705d19283b4cb84c1cd1 263 Gene3D G3DSA:1.10.12.10 222 248 6.0E-8 T 29-03-2018 IPR014748 Crontonase, C-terminal CB4_RS00375 e21f008cfaf1705d19283b4cb84c1cd1 263 SUPERFAMILY SSF52096 14 263 5.81E-66 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS06470 9173eb998fe6269ee31eae9c59b7fd86 191 SUPERFAMILY SSF141523 32 67 7.32E-5 T 29-03-2018 CB4_RS06470 9173eb998fe6269ee31eae9c59b7fd86 191 SUPERFAMILY SSF141523 138 174 7.32E-5 T 29-03-2018 CB4_RS06470 9173eb998fe6269ee31eae9c59b7fd86 191 Pfam PF03734 L,D-transpeptidase catalytic domain 4 178 2.1E-9 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CB4_RS06470 9173eb998fe6269ee31eae9c59b7fd86 191 Gene3D G3DSA:2.40.440.10 2 180 3.6E-10 T 29-03-2018 CB4_RS00625 0b7993fe30497c4c6c9edc7e780a8c47 205 Pfam PF04519 Polymer-forming cytoskeletal 126 182 1.1E-6 T 29-03-2018 IPR007607 Protein of unknown function DUF583 CB4_RS00625 0b7993fe30497c4c6c9edc7e780a8c47 205 Pfam PF13490 Putative zinc-finger 6 36 3.6E-6 T 29-03-2018 IPR027383 Putative zinc-finger CB4_RS19705 a2d3661ad4cad6392771e24a8b3f3e1c 161 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 41 153 3.2E-15 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CB4_RS19705 a2d3661ad4cad6392771e24a8b3f3e1c 161 Gene3D G3DSA:3.10.129.10 19 161 3.7E-27 T 29-03-2018 CB4_RS19705 a2d3661ad4cad6392771e24a8b3f3e1c 161 Pfam PF03061 Thioesterase superfamily 72 146 4.7E-12 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CB4_RS19705 a2d3661ad4cad6392771e24a8b3f3e1c 161 SUPERFAMILY SSF54637 41 154 1.63E-25 T 29-03-2018 IPR029069 HotDog domain CB4_RS01970 db6ce24b137a02625513f3b8bfcb3589 244 Pfam PF04474 Protein of unknown function (DUF554) 4 225 1.9E-74 T 29-03-2018 IPR007563 Protein of unknown function DUF554 CB4_RS10180 3a97e4a25518723d74bdfb805b92afe3 182 SUPERFAMILY SSF47413 13 60 1.26E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS10180 3a97e4a25518723d74bdfb805b92afe3 182 Pfam PF01381 Helix-turn-helix 23 55 1.0E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS10180 3a97e4a25518723d74bdfb805b92afe3 182 Gene3D G3DSA:1.10.260.40 15 182 2.4E-10 T 29-03-2018 CB4_RS04020 096d73734a750a6eea5ef0013f2c623d 276 SUPERFAMILY SSF103481 199 274 5.23E-11 T 29-03-2018 CB4_RS04020 096d73734a750a6eea5ef0013f2c623d 276 SUPERFAMILY SSF103481 37 136 5.49E-8 T 29-03-2018 CB4_RS04020 096d73734a750a6eea5ef0013f2c623d 276 Pfam PF00892 EamA-like transporter family 3 132 1.6E-8 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS04020 096d73734a750a6eea5ef0013f2c623d 276 Pfam PF00892 EamA-like transporter family 147 274 8.7E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS17035 1d3bf8f1a2faff3a778d36d6bae63c48 118 PIRSF PIRSF002030 1 118 5.5E-44 T 29-03-2018 IPR016339 Truncated hemoglobin, group 1 CB4_RS17035 1d3bf8f1a2faff3a778d36d6bae63c48 118 Gene3D G3DSA:1.10.490.10 3 118 1.2E-38 T 29-03-2018 CB4_RS17035 1d3bf8f1a2faff3a778d36d6bae63c48 118 Pfam PF01152 Bacterial-like globin 3 112 5.6E-24 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CB4_RS17035 1d3bf8f1a2faff3a778d36d6bae63c48 118 SUPERFAMILY SSF46458 3 117 2.28E-35 T 29-03-2018 IPR009050 Globin-like CB4_RS13720 b806d6a2973645ae9d9cc352dc1260f2 268 SUPERFAMILY SSF161098 4 253 4.45E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS13720 b806d6a2973645ae9d9cc352dc1260f2 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 261 7.7E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS13720 b806d6a2973645ae9d9cc352dc1260f2 268 Gene3D G3DSA:1.10.3720.10 7 263 2.8E-38 T 29-03-2018 CB4_RS10890 c21e03206d0ca2f494b5e86efd521985 185 Pfam PF00578 AhpC/TSA family 51 169 2.8E-29 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CB4_RS10890 c21e03206d0ca2f494b5e86efd521985 185 SUPERFAMILY SSF52833 49 182 4.5E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS10890 c21e03206d0ca2f494b5e86efd521985 185 Gene3D G3DSA:3.40.30.10 34 184 5.2E-34 T 29-03-2018 CB4_RS02620 b15848e0782c1ddb5bbba87b3841cf1d 997 Pfam PF07940 Heparinase II/III-like protein 464 624 7.2E-12 T 29-03-2018 IPR012480 Heparinase II/III-like GO:0016829 CB4_RS02620 b15848e0782c1ddb5bbba87b3841cf1d 997 Gene3D G3DSA:1.50.10.100 119 438 6.5E-20 T 29-03-2018 CB4_RS02620 b15848e0782c1ddb5bbba87b3841cf1d 997 SUPERFAMILY SSF48230 145 395 3.02E-13 T 29-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CB4_RS17650 2c837e9f335391f90f4bd95b91638d1f 106 Gene3D G3DSA:1.20.1560.10 6 63 5.7E-4 T 29-03-2018 CB4_RS05180 f2ff41105b9ee65dbbce510f6781fe9a 99 Gene3D G3DSA:3.40.30.30 1 96 1.2E-32 T 29-03-2018 CB4_RS05180 f2ff41105b9ee65dbbce510f6781fe9a 99 Pfam PF07315 Protein of unknown function (DUF1462) 5 94 1.3E-31 T 29-03-2018 IPR009190 Protein of unknown function DUF1462 CB4_RS05180 f2ff41105b9ee65dbbce510f6781fe9a 99 SUPERFAMILY SSF52833 2 96 4.4E-30 T 29-03-2018 IPR012336 Thioredoxin-like fold CB4_RS03010 f3c90bbe8128cc87dfdaa21789a5286e 360 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 360 46.023 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03010 f3c90bbe8128cc87dfdaa21789a5286e 360 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 114 284 7.1E-70 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03010 f3c90bbe8128cc87dfdaa21789a5286e 360 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 286 359 1.0E-27 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03010 f3c90bbe8128cc87dfdaa21789a5286e 360 SUPERFAMILY SSF56762 10 359 2.75E-123 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03010 f3c90bbe8128cc87dfdaa21789a5286e 360 Gene3D G3DSA:1.10.645.10 165 355 2.1E-41 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS03010 f3c90bbe8128cc87dfdaa21789a5286e 360 Gene3D G3DSA:1.10.645.10 1 164 4.6E-52 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS18780 bedded6ef4567c5cb2e4063c3d902505 344 Pfam PF13676 TIR domain 4 106 1.0E-9 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CB4_RS18780 bedded6ef4567c5cb2e4063c3d902505 344 Gene3D G3DSA:3.40.50.10140 1 167 1.2E-12 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CB4_RS18780 bedded6ef4567c5cb2e4063c3d902505 344 SUPERFAMILY SSF52200 3 113 4.71E-13 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CB4_RS10485 ec710e02f0114bf6bb7f11535cce2a6e 111 Gene3D G3DSA:3.10.50.10 9 65 1.6E-19 T 29-03-2018 IPR029070 Chitinase insertion domain CB4_RS10485 ec710e02f0114bf6bb7f11535cce2a6e 111 SUPERFAMILY SSF51445 2 7 4.52E-6 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CB4_RS10485 ec710e02f0114bf6bb7f11535cce2a6e 111 SUPERFAMILY SSF51445 66 107 4.52E-6 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CB4_RS14870 ca1246278b907141224f577fd9ae562a 214 SUPERFAMILY SSF51230 38 116 1.41E-7 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS14870 ca1246278b907141224f577fd9ae562a 214 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 86 164 2.4E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CB4_RS14870 ca1246278b907141224f577fd9ae562a 214 Gene3D G3DSA:2.40.50.100 46 101 2.4E-12 T 29-03-2018 CB4_RS14870 ca1246278b907141224f577fd9ae562a 214 Gene3D G3DSA:2.40.50.100 102 188 0.001 T 29-03-2018 CB4_RS10225 885fa2a5189a8a138a2e2e93349f73c6 111 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 105 2.7E-33 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CB4_RS03620 acd53a8c4f96a86a4872ef012ef8b88d 76 SUPERFAMILY SSF81340 5 70 5.36E-5 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CB4_RS17055 69cc819f01e10d95561a3137cf88f880 139 TIGRFAM TIGR02719 repress_PhaQ: poly-beta-hydroxybutyrate-responsive repressor 7 139 1.5E-64 T 29-03-2018 IPR014091 Transcriptional repressor poly-beta-hydroxybutyrate-responsive CB4_RS17055 69cc819f01e10d95561a3137cf88f880 139 Gene3D G3DSA:1.10.10.10 9 123 3.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS17055 69cc819f01e10d95561a3137cf88f880 139 Pfam PF03551 Transcriptional regulator PadR-like family 33 103 2.0E-18 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CB4_RS17055 69cc819f01e10d95561a3137cf88f880 139 SUPERFAMILY SSF46785 17 114 5.34E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS15795 8d088afa7156305392ab1de31804ea1a 72 SUPERFAMILY SSF47413 1 69 1.38E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CB4_RS15795 8d088afa7156305392ab1de31804ea1a 72 Gene3D G3DSA:1.10.260.40 4 72 1.4E-10 T 29-03-2018 CB4_RS15795 8d088afa7156305392ab1de31804ea1a 72 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 68 2.5E-23 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS15795 8d088afa7156305392ab1de31804ea1a 72 SMART SM00530 6 62 1.6E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CB4_RS14620 23984f607bbd5c1d54528bdaad343ca4 49 Pfam PF13076 Fur-regulated basic protein A 6 28 3.8E-7 T 29-03-2018 IPR025072 Fur-regulated basic protein A CB4_RS03085 0019b2668c932d841d7ac8adb82c724e 95 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 80 4.7E-45 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CB4_RS03085 0019b2668c932d841d7ac8adb82c724e 95 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CB4_RS03085 0019b2668c932d841d7ac8adb82c724e 95 Pfam PF12116 Stage III sporulation protein D 2 82 9.5E-41 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CB4_RS03085 0019b2668c932d841d7ac8adb82c724e 95 Gene3D G3DSA:1.10.10.10 2 31 1.0E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03085 0019b2668c932d841d7ac8adb82c724e 95 Gene3D G3DSA:1.10.260.40 32 85 1.7E-5 T 29-03-2018 CB4_RS07195 3e77ba62be6bda2440e9d2f2d9dbc32f 300 Pfam PF03405 Fatty acid desaturase 9 298 5.1E-46 T 29-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CB4_RS07195 3e77ba62be6bda2440e9d2f2d9dbc32f 300 Gene3D G3DSA:1.10.620.20 4 300 1.7E-63 T 29-03-2018 CB4_RS07195 3e77ba62be6bda2440e9d2f2d9dbc32f 300 SUPERFAMILY SSF47240 6 296 3.66E-57 T 29-03-2018 IPR009078 Ferritin-like superfamily CB4_RS16720 7c59774c39f22e720f008529ac646e7d 144 Pfam PF06491 Disulphide isomerase 7 143 5.4E-60 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CB4_RS16720 7c59774c39f22e720f008529ac646e7d 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 7 143 1.4E-61 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CB4_RS02145 2870facf939ec49e26f88f0c61c83fef 445 Gene3D G3DSA:3.90.1200.10 1 301 1.7E-5 T 29-03-2018 CB4_RS02145 2870facf939ec49e26f88f0c61c83fef 445 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 38 437 4.3E-100 T 29-03-2018 IPR018721 Protein of unknown function DUF2252 CB4_RS07820 d0b374c17b2b1713f99d135dc0b5172c 462 Pfam PF07676 WD40-like Beta Propeller Repeat 181 201 0.09 T 29-03-2018 IPR011659 WD40-like Beta Propeller CB4_RS07820 d0b374c17b2b1713f99d135dc0b5172c 462 Gene3D G3DSA:2.130.10.150 42 191 2.8E-11 T 29-03-2018 CB4_RS07820 d0b374c17b2b1713f99d135dc0b5172c 462 Gene3D G3DSA:2.130.10.120 244 447 2.8E-13 T 29-03-2018 CB4_RS07820 d0b374c17b2b1713f99d135dc0b5172c 462 Gene3D G3DSA:2.130.10.10 192 243 0.0026 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CB4_RS07820 d0b374c17b2b1713f99d135dc0b5172c 462 SUPERFAMILY SSF69304 44 330 3.27E-21 T 29-03-2018 CB4_RS05165 f8bba5030efbb5c38c4ae4b0d6619e9c 84 Gene3D G3DSA:3.30.300.130 10 84 4.9E-26 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CB4_RS05165 f8bba5030efbb5c38c4ae4b0d6619e9c 84 Pfam PF01106 NifU-like domain 15 80 8.7E-27 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CB4_RS05165 f8bba5030efbb5c38c4ae4b0d6619e9c 84 SUPERFAMILY SSF117916 9 83 1.59E-24 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CB4_RS05165 f8bba5030efbb5c38c4ae4b0d6619e9c 84 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 19 83 2.0E-22 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CB4_RS12300 038abb173c2462f3aa9a1eed3001f661 265 Pfam PF03988 Repeat of Unknown Function (DUF347) 143 188 3.1E-8 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CB4_RS12300 038abb173c2462f3aa9a1eed3001f661 265 Pfam PF03988 Repeat of Unknown Function (DUF347) 26 74 8.7E-8 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CB4_RS12300 038abb173c2462f3aa9a1eed3001f661 265 Pfam PF03988 Repeat of Unknown Function (DUF347) 78 128 1.4E-12 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CB4_RS12300 038abb173c2462f3aa9a1eed3001f661 265 Pfam PF03988 Repeat of Unknown Function (DUF347) 198 253 1.1E-11 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CB4_RS16545 d43b682497a99346ea7fa915c9f32797 291 SUPERFAMILY SSF52768 20 288 1.75E-81 T 29-03-2018 CB4_RS16545 d43b682497a99346ea7fa915c9f32797 291 ProSitePatterns PS01053 Arginase family signature. 216 237 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CB4_RS16545 d43b682497a99346ea7fa915c9f32797 291 TIGRFAM TIGR01230 agmatinase: agmatinase 15 286 1.7E-85 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CB4_RS16545 d43b682497a99346ea7fa915c9f32797 291 PIRSF PIRSF036979 2 291 1.1E-90 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS16545 d43b682497a99346ea7fa915c9f32797 291 Gene3D G3DSA:3.40.800.10 18 291 7.3E-81 T 29-03-2018 CB4_RS16545 d43b682497a99346ea7fa915c9f32797 291 Pfam PF00491 Arginase family 26 285 6.8E-78 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CB4_RS16190 c4035783584d0ad9d649d0190a5a222d 141 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 25 141 1.0E-28 T 29-03-2018 IPR020144 Stage V sporulation protein AB CB4_RS16190 c4035783584d0ad9d649d0190a5a222d 141 Pfam PF13782 Stage V sporulation protein AB 29 137 1.1E-31 T 29-03-2018 IPR020144 Stage V sporulation protein AB CB4_RS15790 fa83fc5750ebc7c0db7ddb86fd857cee 57 Gene3D G3DSA:1.10.443.10 1 57 5.5E-13 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS15790 fa83fc5750ebc7c0db7ddb86fd857cee 57 Pfam PF00589 Phage integrase family 3 45 5.4E-11 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS15790 fa83fc5750ebc7c0db7ddb86fd857cee 57 SUPERFAMILY SSF56349 3 55 6.18E-13 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS12650 5e0c138169436d526ac3bcbaba097e42 373 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 3 369 2.0E-85 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS12650 5e0c138169436d526ac3bcbaba097e42 373 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 208 368 1.8E-26 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS05885 0b029ee9de071f3dc092972654dbfa48 198 Pfam PF09335 SNARE associated Golgi protein 30 156 7.0E-17 T 29-03-2018 IPR032816 SNARE associated Golgi protein CB4_RS03125 d07754166676bfba6ba2f14f7111fb0d 354 Pfam PF00953 Glycosyl transferase family 4 75 228 2.3E-43 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CB4_RS03125 d07754166676bfba6ba2f14f7111fb0d 354 ProSitePatterns PS01348 MraY family signature 2. 148 159 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CB4_RS09630 83d34f51d00e3b638f5992d2ffdb9bfc 414 Gene3D G3DSA:1.20.1250.20 212 408 5.6E-16 T 29-03-2018 CB4_RS09630 83d34f51d00e3b638f5992d2ffdb9bfc 414 Gene3D G3DSA:1.20.1250.20 10 210 1.5E-22 T 29-03-2018 CB4_RS09630 83d34f51d00e3b638f5992d2ffdb9bfc 414 Pfam PF07690 Major Facilitator Superfamily 21 255 2.6E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CB4_RS09630 83d34f51d00e3b638f5992d2ffdb9bfc 414 SUPERFAMILY SSF103473 14 403 1.57E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS18905 55165ff3d963da8e69b13c99b7d791ee 272 PIRSF PIRSF002854 1 272 3.0E-91 T 29-03-2018 IPR004872 Lipoprotein NlpA family CB4_RS18905 55165ff3d963da8e69b13c99b7d791ee 272 Gene3D G3DSA:3.40.190.10 33 132 1.2E-19 T 29-03-2018 CB4_RS18905 55165ff3d963da8e69b13c99b7d791ee 272 Pfam PF03180 NLPA lipoprotein 34 272 1.3E-75 T 29-03-2018 IPR004872 Lipoprotein NlpA family CB4_RS18905 55165ff3d963da8e69b13c99b7d791ee 272 Gene3D G3DSA:3.40.190.10 133 272 7.6E-46 T 29-03-2018 CB4_RS18905 55165ff3d963da8e69b13c99b7d791ee 272 SUPERFAMILY SSF53850 33 272 2.0E-68 T 29-03-2018 CB4_RS19215 f2a425af422dd42552670554c12ee239 177 Pfam PF03079 ARD/ARD' family 6 168 6.7E-38 T 29-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 CB4_RS19215 f2a425af422dd42552670554c12ee239 177 SUPERFAMILY SSF51182 8 174 1.05E-30 T 29-03-2018 IPR011051 RmlC-like cupin domain CB4_RS19215 f2a425af422dd42552670554c12ee239 177 Gene3D G3DSA:2.60.120.10 1 160 6.4E-37 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CB4_RS19215 f2a425af422dd42552670554c12ee239 177 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 175 28.674 T 29-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 CB4_RS09720 1f8bc0d87dbb2726b9cb944c03022d6e 59 Gene3D G3DSA:1.20.930.10 4 52 2.5E-4 T 29-03-2018 CB4_RS05010 0b22a2102d4ec473f36743639e7f7e45 310 SUPERFAMILY SSF103481 38 142 1.28E-15 T 29-03-2018 CB4_RS05010 0b22a2102d4ec473f36743639e7f7e45 310 SUPERFAMILY SSF103481 187 287 1.7E-9 T 29-03-2018 CB4_RS05010 0b22a2102d4ec473f36743639e7f7e45 310 Pfam PF00892 EamA-like transporter family 6 139 3.8E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS05010 0b22a2102d4ec473f36743639e7f7e45 310 Pfam PF00892 EamA-like transporter family 153 287 3.2E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CB4_RS18900 adbe6dfe8ca2254a9bfe6e9c9e22c656 102 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 2.7E-16 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CB4_RS18900 adbe6dfe8ca2254a9bfe6e9c9e22c656 102 SUPERFAMILY SSF54909 1 95 8.23E-21 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CB4_RS18900 adbe6dfe8ca2254a9bfe6e9c9e22c656 102 Gene3D G3DSA:3.30.70.100 1 102 4.3E-23 T 29-03-2018 CB4_RS11725 c4cb0f0ad202c5bbb64d7b579fb32986 89 SUPERFAMILY SSF88697 8 75 2.1E-14 T 29-03-2018 IPR015947 PUA-like domain CB4_RS11725 c4cb0f0ad202c5bbb64d7b579fb32986 89 Gene3D G3DSA:2.30.130.30 1 83 2.1E-29 T 29-03-2018 CB4_RS11725 c4cb0f0ad202c5bbb64d7b579fb32986 89 Pfam PF12961 Domain of Unknown Function with PDB structure (DUF3850) 10 82 5.0E-29 T 29-03-2018 CB4_RS08425 a39191dc8e6b093f8664be1e3a357ba0 192 SUPERFAMILY SSF52980 9 190 2.2E-40 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CB4_RS08425 a39191dc8e6b093f8664be1e3a357ba0 192 Gene3D G3DSA:3.90.1570.10 3 190 7.7E-48 T 29-03-2018 CB4_RS08425 a39191dc8e6b093f8664be1e3a357ba0 192 Pfam PF05685 Putative restriction endonuclease 15 182 3.5E-36 T 29-03-2018 IPR008538 Domain of unknown function DUF820 CB4_RS03480 8ef2f23cf0e3ae3ecd1570d902eba98f 177 SUPERFAMILY SSF101116 24 130 2.88E-22 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CB4_RS03480 8ef2f23cf0e3ae3ecd1570d902eba98f 177 Pfam PF02561 Flagellar protein FliS 25 124 1.3E-21 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CB4_RS03480 8ef2f23cf0e3ae3ecd1570d902eba98f 177 Gene3D G3DSA:1.20.120.340 25 127 2.4E-21 T 29-03-2018 CB4_RS14850 c0bea00d39e022ac16386714b01f23ce 430 Gene3D G3DSA:3.30.830.10 2 222 6.4E-52 T 29-03-2018 CB4_RS14850 c0bea00d39e022ac16386714b01f23ce 430 Pfam PF00675 Insulinase (Peptidase family M16) 63 173 4.1E-17 T 29-03-2018 IPR011765 Peptidase M16, N-terminal CB4_RS14850 c0bea00d39e022ac16386714b01f23ce 430 Pfam PF05193 Peptidase M16 inactive domain 181 360 1.5E-17 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CB4_RS14850 c0bea00d39e022ac16386714b01f23ce 430 SUPERFAMILY SSF63411 14 219 3.84E-43 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CB4_RS14850 c0bea00d39e022ac16386714b01f23ce 430 SUPERFAMILY SSF63411 237 425 1.19E-15 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CB4_RS14850 c0bea00d39e022ac16386714b01f23ce 430 Gene3D G3DSA:3.30.830.10 223 430 6.3E-24 T 29-03-2018 CB4_RS17045 201cb5acc709bdbbd461d731b6091932 147 Gene3D G3DSA:3.10.129.10 13 145 2.7E-40 T 29-03-2018 CB4_RS17045 201cb5acc709bdbbd461d731b6091932 147 Pfam PF01575 MaoC like domain 25 129 6.2E-27 T 29-03-2018 IPR002539 MaoC-like domain CB4_RS17045 201cb5acc709bdbbd461d731b6091932 147 SUPERFAMILY SSF54637 12 146 1.33E-43 T 29-03-2018 IPR029069 HotDog domain CB4_RS13790 81178bb673a25515a11e483befb95d75 412 Gene3D G3DSA:3.90.550.10 36 306 1.3E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS13790 81178bb673a25515a11e483befb95d75 412 SUPERFAMILY SSF53448 47 313 7.31E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CB4_RS13790 81178bb673a25515a11e483befb95d75 412 Pfam PF13641 Glycosyltransferase like family 2 48 272 6.7E-24 T 29-03-2018 CB4_RS04950 0633b30fde8bb64ab6decb9363ccd963 376 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 23 120 6.5E-10 T 29-03-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain CB4_RS09020 0385b6727683abd64c768b5e57a8e590 124 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 21 115 5.6E-30 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain CB4_RS09020 0385b6727683abd64c768b5e57a8e590 124 Gene3D G3DSA:1.10.8.80 20 121 4.5E-4 T 29-03-2018 CB4_RS17050 2bf7e046caa754c60bd7976412fc3cc4 190 Pfam PF09602 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) 19 179 6.6E-37 T 29-03-2018 IPR011728 Polyhydroxyalkanoic acid inclusion protein PhaP CB4_RS17050 2bf7e046caa754c60bd7976412fc3cc4 190 TIGRFAM TIGR02131 phaP_Bmeg: polyhydroxyalkanoic acid inclusion protein PhaP 18 179 7.5E-35 T 29-03-2018 IPR011728 Polyhydroxyalkanoic acid inclusion protein PhaP CB4_RS05735 bdc3c6a1d7222339af1f3935a56756cd 258 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 31 1.3E-4 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CB4_RS03200 c9ce36befa819a5ff9bd3a610b7d5c89 275 Pfam PF05853 beta-keto acid cleavage enzyme 3 273 2.9E-78 T 29-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CB4_RS03200 c9ce36befa819a5ff9bd3a610b7d5c89 275 Gene3D G3DSA:3.20.20.70 1 274 3.4E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS05280 1948e02fa7b96b2e07e4f22de957a0f4 191 SUPERFAMILY SSF50685 102 150 5.23E-7 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CB4_RS05280 1948e02fa7b96b2e07e4f22de957a0f4 191 Pfam PF06725 3D domain 103 164 4.6E-19 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CB4_RS05280 1948e02fa7b96b2e07e4f22de957a0f4 191 Gene3D G3DSA:2.40.40.10 5 177 5.7E-34 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CB4_RS17485 809599d4f707dc6b51481ed66a479c0b 516 Gene3D G3DSA:3.30.457.10 420 498 4.0E-12 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS17485 809599d4f707dc6b51481ed66a479c0b 516 Pfam PF07833 Copper amine oxidase N-terminal domain 418 504 2.4E-14 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS17485 809599d4f707dc6b51481ed66a479c0b 516 SUPERFAMILY SSF55383 420 503 1.44E-13 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS19310 9e6115d636a157dcb92220a761e0c160 330 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 2 170 6.4E-22 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CB4_RS14405 48778ace8aed1052f6efe92ef48b5674 219 SUPERFAMILY SSF56214 105 206 4.58E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS14405 48778ace8aed1052f6efe92ef48b5674 219 Gene3D G3DSA:3.90.470.20 115 213 2.9E-11 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS14405 48778ace8aed1052f6efe92ef48b5674 219 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 105 195 4.8E-13 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS14405 48778ace8aed1052f6efe92ef48b5674 219 SUPERFAMILY SSF56214 15 97 8.37E-15 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS14405 48778ace8aed1052f6efe92ef48b5674 219 Gene3D G3DSA:3.90.470.20 2 114 8.1E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CB4_RS03800 b49c99e5eb8fe1565cd7ee5d477caabd 293 Pfam PF03668 P-loop ATPase protein family 9 290 1.0E-115 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CB4_RS03800 b49c99e5eb8fe1565cd7ee5d477caabd 293 Gene3D G3DSA:3.40.50.300 9 164 5.5E-9 T 29-03-2018 CB4_RS03800 b49c99e5eb8fe1565cd7ee5d477caabd 293 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 9 290 42.402 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CB4_RS03800 b49c99e5eb8fe1565cd7ee5d477caabd 293 PIRSF PIRSF005052 9 292 8.0E-110 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CB4_RS03800 b49c99e5eb8fe1565cd7ee5d477caabd 293 SUPERFAMILY SSF52540 11 166 7.43E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS16985 bc85f0bc409e3ed81f17ff701fd1bc59 123 Pfam PF00072 Response regulator receiver domain 5 112 1.4E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16985 bc85f0bc409e3ed81f17ff701fd1bc59 123 SMART SM00448 3 114 6.8E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS16985 bc85f0bc409e3ed81f17ff701fd1bc59 123 Gene3D G3DSA:3.40.50.2300 1 122 4.9E-38 T 29-03-2018 CB4_RS16985 bc85f0bc409e3ed81f17ff701fd1bc59 123 SUPERFAMILY SSF52172 3 119 1.35E-38 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS01190 d4809904cd54897dfa4f72eb3f080691 170 Gene3D G3DSA:3.40.50.1010 1 77 0.083 T 29-03-2018 IPR029060 PIN domain-like CB4_RS01190 d4809904cd54897dfa4f72eb3f080691 170 Pfam PF05991 YacP-like NYN domain 5 167 4.6E-54 T 29-03-2018 IPR010298 Protein of unknown function DUF901 CB4_RS16255 d3ad16bd784951a3b617aa7e392d67d3 310 SUPERFAMILY SSF161098 102 309 1.83E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS16255 d3ad16bd784951a3b617aa7e392d67d3 310 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 78 7.5E-17 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CB4_RS16255 d3ad16bd784951a3b617aa7e392d67d3 310 Gene3D G3DSA:1.10.3720.10 36 298 5.8E-45 T 29-03-2018 CB4_RS16255 d3ad16bd784951a3b617aa7e392d67d3 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 310 1.8E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS16305 e5721034531ae4bebd99a67b28ee662f 693 Gene3D G3DSA:3.40.710.10 269 678 1.5E-81 T 29-03-2018 CB4_RS16305 e5721034531ae4bebd99a67b28ee662f 693 Pfam PF03717 Penicillin-binding Protein dimerisation domain 63 254 1.6E-31 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CB4_RS16305 e5721034531ae4bebd99a67b28ee662f 693 SUPERFAMILY SSF56601 366 677 3.13E-75 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS16305 e5721034531ae4bebd99a67b28ee662f 693 SUPERFAMILY SSF56601 220 325 3.13E-75 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CB4_RS16305 e5721034531ae4bebd99a67b28ee662f 693 SUPERFAMILY SSF56519 58 268 1.27E-33 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CB4_RS16305 e5721034531ae4bebd99a67b28ee662f 693 Gene3D G3DSA:3.90.1310.10 31 268 9.9E-43 T 29-03-2018 CB4_RS16305 e5721034531ae4bebd99a67b28ee662f 693 Pfam PF00905 Penicillin binding protein transpeptidase domain 302 666 2.2E-59 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CB4_RS04910 b1a9fa26075cdb42f32a3968c4f84657 437 Pfam PF01593 Flavin containing amine oxidoreductase 18 262 9.3E-21 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CB4_RS04910 b1a9fa26075cdb42f32a3968c4f84657 437 Gene3D G3DSA:3.50.50.60 5 436 3.9E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS04910 b1a9fa26075cdb42f32a3968c4f84657 437 SUPERFAMILY SSF51905 393 432 1.65E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS04910 b1a9fa26075cdb42f32a3968c4f84657 437 SUPERFAMILY SSF51905 7 296 1.65E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CB4_RS13500 9c9a7ba5dbff34f44f95658d5404fb62 276 Gene3D G3DSA:3.40.50.720 1 258 8.4E-38 T 29-03-2018 CB4_RS13500 9c9a7ba5dbff34f44f95658d5404fb62 276 PIRSF PIRSF000094 2 263 1.1E-91 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CB4_RS13500 9c9a7ba5dbff34f44f95658d5404fb62 276 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 255 1.2E-76 T 29-03-2018 CB4_RS13500 9c9a7ba5dbff34f44f95658d5404fb62 276 SUPERFAMILY SSF51735 6 258 7.86E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS13500 9c9a7ba5dbff34f44f95658d5404fb62 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS13500 9c9a7ba5dbff34f44f95658d5404fb62 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS13500 9c9a7ba5dbff34f44f95658d5404fb62 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS13500 9c9a7ba5dbff34f44f95658d5404fb62 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS09955 bff804b926a77a35675407b5cbe788a8 66 SUPERFAMILY SSF55008 2 65 2.75E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CB4_RS09955 bff804b926a77a35675407b5cbe788a8 66 Pfam PF00403 Heavy-metal-associated domain 5 64 1.4E-12 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CB4_RS09955 bff804b926a77a35675407b5cbe788a8 66 PRINTS PR00944 Copper ion binding protein signature 52 65 3.1E-6 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CB4_RS09955 bff804b926a77a35675407b5cbe788a8 66 PRINTS PR00944 Copper ion binding protein signature 15 28 3.1E-6 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CB4_RS09955 bff804b926a77a35675407b5cbe788a8 66 PRINTS PR00944 Copper ion binding protein signature 3 15 3.1E-6 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CB4_RS09955 bff804b926a77a35675407b5cbe788a8 66 Gene3D G3DSA:3.30.70.100 1 66 2.6E-18 T 29-03-2018 CB4_RS09955 bff804b926a77a35675407b5cbe788a8 66 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 4 65 4.0E-19 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CB4_RS12565 71ddf6d11b15ecd3c0fbdbc1db2a25dd 80 Gene3D G3DSA:3.10.20.30 2 80 2.5E-20 T 29-03-2018 IPR012675 Beta-grasp domain CB4_RS12565 71ddf6d11b15ecd3c0fbdbc1db2a25dd 80 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 80 4.3E-20 T 29-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CB4_RS12565 71ddf6d11b15ecd3c0fbdbc1db2a25dd 80 SUPERFAMILY SSF54285 1 80 4.94E-18 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CB4_RS12565 71ddf6d11b15ecd3c0fbdbc1db2a25dd 80 Pfam PF02597 ThiS family 4 80 1.6E-13 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CB4_RS12625 ade71dba8f19a78a25b66433d294b478 80 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 5 76 5.2E-28 T 29-03-2018 IPR018680 Protein of unknown function DUF2164 CB4_RS16890 d88800d106cb3a30370d437c2d67f29f 300 SUPERFAMILY SSF55120 79 297 4.32E-71 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS16890 d88800d106cb3a30370d437c2d67f29f 300 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS16890 d88800d106cb3a30370d437c2d67f29f 300 Pfam PF00849 RNA pseudouridylate synthase 95 244 4.3E-31 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS16890 d88800d106cb3a30370d437c2d67f29f 300 Gene3D G3DSA:3.10.290.10 4 79 8.7E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CB4_RS16890 d88800d106cb3a30370d437c2d67f29f 300 Gene3D G3DSA:3.30.2350.10 89 300 6.9E-67 T 29-03-2018 CB4_RS16890 d88800d106cb3a30370d437c2d67f29f 300 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 28 297 5.7E-71 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CB4_RS13735 7aa775b7f5ea669201d622ca007ed92f 439 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 25 409 6.6E-39 T 29-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB CB4_RS13735 7aa775b7f5ea669201d622ca007ed92f 439 SUPERFAMILY SSF103473 7 416 2.22E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CB4_RS13735 7aa775b7f5ea669201d622ca007ed92f 439 Gene3D G3DSA:1.20.1250.20 4 207 3.8E-24 T 29-03-2018 CB4_RS13735 7aa775b7f5ea669201d622ca007ed92f 439 Gene3D G3DSA:1.20.1250.20 223 418 6.1E-32 T 29-03-2018 CB4_RS04160 301afd190d2b5f6d4a1ed8406dba0c6c 353 SUPERFAMILY SSF64182 49 351 1.18E-25 T 29-03-2018 CB4_RS02265 b896887fcfcd68780714fdb949449a1f 64 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 2 62 5.8E-32 T 29-03-2018 IPR019240 Protein of unknown function DUF2196 CB4_RS02265 b896887fcfcd68780714fdb949449a1f 64 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 2 62 2.2E-34 T 29-03-2018 IPR019240 Protein of unknown function DUF2196 CB4_RS16650 5e85eb314aea105d4d74c0234533a8ff 100 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 3 92 6.6E-28 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CB4_RS16650 5e85eb314aea105d4d74c0234533a8ff 100 SUPERFAMILY SSF55248 2 93 2.35E-29 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CB4_RS16650 5e85eb314aea105d4d74c0234533a8ff 100 Gene3D G3DSA:3.30.1360.20 2 99 9.3E-31 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CB4_RS16650 5e85eb314aea105d4d74c0234533a8ff 100 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 93 22.135 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CB4_RS00595 87f939407fbf0b8988a5e225970ec7bd 173 SUPERFAMILY SSF109854 3 172 3.97E-47 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CB4_RS00595 87f939407fbf0b8988a5e225970ec7bd 173 Gene3D G3DSA:1.20.120.450 1 173 2.1E-37 T 29-03-2018 CB4_RS00595 87f939407fbf0b8988a5e225970ec7bd 173 Pfam PF12867 DinB superfamily 34 163 1.3E-15 T 29-03-2018 IPR024775 DinB-like domain CB4_RS00595 87f939407fbf0b8988a5e225970ec7bd 173 Hamap MF_01256 Putative metal-dependent hydrolase . 1 173 40.217 T 29-03-2018 IPR023774 Putative metal-dependent hydrolase YfiT CB4_RS13380 6b470a246fa83b430c6f0d79bade0ce0 157 Gene3D G3DSA:1.20.1170.10 4 151 5.9E-8 T 29-03-2018 CB4_RS05070 e362b9855bda98835fa79307a7bef037 275 SUPERFAMILY SSF58104 109 267 7.32E-35 T 29-03-2018 CB4_RS05070 e362b9855bda98835fa79307a7bef037 275 SMART SM00283 62 273 7.5E-4 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS05070 e362b9855bda98835fa79307a7bef037 275 Gene3D G3DSA:3.30.450.20 3 104 4.2E-4 T 29-03-2018 CB4_RS05070 e362b9855bda98835fa79307a7bef037 275 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 132 262 6.1E-24 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS05070 e362b9855bda98835fa79307a7bef037 275 Gene3D G3DSA:1.10.287.950 105 271 2.6E-31 T 29-03-2018 CB4_RS01860 4d9852b86bec733f67c02baa5227ab65 356 Pfam PF14175 YaaC-like Protein 25 344 6.9E-70 T 29-03-2018 IPR026988 YaaC-like protein CB4_RS11160 0c1b5ec14080db5c4699c98243e01dde 664 Gene3D G3DSA:2.160.20.10 224 657 0.0012 T 29-03-2018 IPR012334 Pectin lyase fold CB4_RS11160 0c1b5ec14080db5c4699c98243e01dde 664 Pfam PF07581 The GLUG motif 470 492 0.0025 T 29-03-2018 IPR011493 GLUG CB4_RS11160 0c1b5ec14080db5c4699c98243e01dde 664 Pfam PF07581 The GLUG motif 496 520 9.4E-4 T 29-03-2018 IPR011493 GLUG CB4_RS09120 71ce0050a16e5aecf6985504bd68b0c7 431 Pfam PF02120 Flagellar hook-length control protein FliK 297 374 1.5E-14 T 29-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CB4_RS13180 335c82e6044419e7f8f201178f2387ce 481 Gene3D G3DSA:3.40.309.10 264 458 9.8E-63 T 29-03-2018 CB4_RS13180 335c82e6044419e7f8f201178f2387ce 481 Pfam PF00171 Aldehyde dehydrogenase family 12 472 8.4E-161 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CB4_RS13180 335c82e6044419e7f8f201178f2387ce 481 SUPERFAMILY SSF53720 2 475 2.88E-155 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CB4_RS13180 335c82e6044419e7f8f201178f2387ce 481 Gene3D G3DSA:3.40.605.10 1 263 3.0E-88 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CB4_RS05450 8c8df7725f9cc3e25f66762a7e83d107 168 Pfam PF14221 Domain of unknown function (DUF4330) 1 162 4.2E-26 T 29-03-2018 IPR025480 Protein of unknown function DUF4330 CB4_RS10700 b4fbb49df87d930a6fdd6ad1cd2ff66e 356 Pfam PF03050 Transposase IS66 family 109 318 1.4E-42 T 29-03-2018 IPR004291 Transposase, IS66 CB4_RS17725 fda54603209bbfa26cb371599f896c39 494 Gene3D G3DSA:3.40.720.10 3 489 1.3E-30 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CB4_RS17725 fda54603209bbfa26cb371599f896c39 494 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 282 4.5E-23 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CB4_RS17725 fda54603209bbfa26cb371599f896c39 494 SUPERFAMILY SSF53649 413 481 8.01E-46 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CB4_RS17725 fda54603209bbfa26cb371599f896c39 494 SUPERFAMILY SSF53649 4 354 8.01E-46 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CB4_RS13230 9c1c905ee5ae9d3dc9c4a12c497b7dcb 48 Gene3D G3DSA:1.10.287.1100 10 42 8.2E-10 T 29-03-2018 IPR015064 Sporulation inhibitor A CB4_RS13230 9c1c905ee5ae9d3dc9c4a12c497b7dcb 48 Pfam PF08970 Sporulation inhibitor A 9 47 1.1E-11 T 29-03-2018 IPR015064 Sporulation inhibitor A CB4_RS13230 9c1c905ee5ae9d3dc9c4a12c497b7dcb 48 SUPERFAMILY SSF100985 9 47 4.05E-9 T 29-03-2018 IPR015064 Sporulation inhibitor A CB4_RS12925 25ccb817189e8e2cd52adbcd157a9475 147 Gene3D G3DSA:3.40.630.30 2 141 1.8E-26 T 29-03-2018 CB4_RS12925 25ccb817189e8e2cd52adbcd157a9475 147 SUPERFAMILY SSF55729 3 138 5.48E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS12925 25ccb817189e8e2cd52adbcd157a9475 147 Pfam PF00583 Acetyltransferase (GNAT) family 20 136 6.7E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS07945 522caf3698ed3c718b8532837b200246 189 Pfam PF03780 Asp23 family, cell envelope-related function 125 176 2.1E-8 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 CB4_RS01000 f87c624648faf87f90b51b865560b509 63 SUPERFAMILY SSF47598 3 49 5.78E-12 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CB4_RS01000 f87c624648faf87f90b51b865560b509 63 Gene3D G3DSA:1.10.1220.10 4 44 1.2E-16 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CB4_RS05535 39f47065e86b7106b4be2722f746c6b6 216 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 93 195 1.5E-9 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS05535 39f47065e86b7106b4be2722f746c6b6 216 Gene3D G3DSA:1.20.1300.10 2 212 3.5E-39 T 29-03-2018 CB4_RS05535 39f47065e86b7106b4be2722f746c6b6 216 PIRSF PIRSF000170 1 208 3.3E-89 T 29-03-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute CB4_RS05535 39f47065e86b7106b4be2722f746c6b6 216 SUPERFAMILY SSF81343 4 205 6.38E-53 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CB4_RS05535 39f47065e86b7106b4be2722f746c6b6 216 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 7 204 2.3E-41 T 29-03-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit CB4_RS19955 e51295f3a87d29eb380459fff87f8f89 117 Pfam PF01527 Transposase 25 102 8.4E-16 T 29-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CB4_RS19955 e51295f3a87d29eb380459fff87f8f89 117 Gene3D G3DSA:1.10.10.60 29 111 3.8E-20 T 29-03-2018 CB4_RS19955 e51295f3a87d29eb380459fff87f8f89 117 SUPERFAMILY SSF46689 25 115 1.79E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS20685 e9c76435d10cac0babd8357d4c10ec6d 328 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 10 299 1.3E-22 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CB4_RS10195 381b83801d3e488db3046d4d30f77f21 293 Pfam PF12679 ABC-2 family transporter protein 11 260 6.5E-13 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CB4_RS10195 381b83801d3e488db3046d4d30f77f21 293 Gene3D G3DSA:1.10.287.70 14 290 0.0087 T 29-03-2018 CB4_RS19760 ce9b26b8cd75807a2c11d12c64769f70 221 Gene3D G3DSA:1.10.3720.10 7 221 5.3E-36 T 29-03-2018 CB4_RS19760 ce9b26b8cd75807a2c11d12c64769f70 221 SUPERFAMILY SSF161098 12 205 2.09E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS19760 ce9b26b8cd75807a2c11d12c64769f70 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 221 3.3E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS05205 f241ad45ed4948ae1c87b1bf3b31ee50 89 Gene3D G3DSA:3.90.20.10 1 87 2.9E-5 T 29-03-2018 CB4_RS19695 dc470aeaae361db6daf6c2379b91ac53 320 SUPERFAMILY SSF160240 230 302 2.75E-10 T 29-03-2018 CB4_RS19695 dc470aeaae361db6daf6c2379b91ac53 320 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 29 304 4.2E-93 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CB4_RS19695 dc470aeaae361db6daf6c2379b91ac53 320 Gene3D G3DSA:3.30.70.1350 229 307 2.2E-12 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CB4_RS19695 dc470aeaae361db6daf6c2379b91ac53 320 Pfam PF01545 Cation efflux family 34 225 2.1E-51 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CB4_RS19695 dc470aeaae361db6daf6c2379b91ac53 320 Gene3D G3DSA:1.20.1510.10 27 225 1.7E-60 T 29-03-2018 CB4_RS19695 dc470aeaae361db6daf6c2379b91ac53 320 SUPERFAMILY SSF161111 28 226 1.15E-61 T 29-03-2018 CB4_RS18840 d4a6e9ace4acd05c5407cdc84573acca 119 Pfam PF11964 SpoIIAA-like 12 116 4.1E-18 T 29-03-2018 IPR021866 SpoIIAA-like CB4_RS18840 d4a6e9ace4acd05c5407cdc84573acca 119 SUPERFAMILY SSF52091 1 116 3.37E-30 T 29-03-2018 IPR002645 STAS domain CB4_RS18840 d4a6e9ace4acd05c5407cdc84573acca 119 Gene3D G3DSA:3.40.50.10600 1 118 1.0E-19 T 29-03-2018 CB4_RS01300 d6c0efa7830eae95392fdff2219646d2 379 SUPERFAMILY SSF53098 84 329 2.05E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS01300 d6c0efa7830eae95392fdff2219646d2 379 Gene3D G3DSA:3.90.350.10 89 296 6.8E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CB4_RS01300 d6c0efa7830eae95392fdff2219646d2 379 Pfam PF01609 Transposase DDE domain 111 320 4.5E-31 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CB4_RS17810 05f73e4ac88ddc70d40cfeb3f778be4f 227 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 184 6.8E-70 T 29-03-2018 IPR022301 Integral membrane protein YjbE CB4_RS17810 05f73e4ac88ddc70d40cfeb3f778be4f 227 Pfam PF03741 Integral membrane protein TerC family 14 183 1.9E-44 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CB4_RS09130 0a9b3f1e6ddd3df5c3b26480d16a8e79 125 Pfam PF12611 Putative flagellar 102 124 2.0E-12 T 29-03-2018 IPR013367 Flagellar, putative CB4_RS09130 0a9b3f1e6ddd3df5c3b26480d16a8e79 125 TIGRFAM TIGR02530 flg_new: flagellar operon protein 29 125 1.1E-33 T 29-03-2018 IPR013367 Flagellar, putative CB4_RS13490 bf6d16be16fc77ffc44ac51a46e032fd 263 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 5 247 2.0E-56 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CB4_RS13490 bf6d16be16fc77ffc44ac51a46e032fd 263 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 2 255 14.206 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CB4_RS13490 bf6d16be16fc77ffc44ac51a46e032fd 263 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 5 259 6.9E-51 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CB4_RS10770 9071848a39634f9b12e4f718f3e81d02 72 Gene3D G3DSA:3.30.70.790 20 48 0.36 T 29-03-2018 CB4_RS10770 9071848a39634f9b12e4f718f3e81d02 72 Gene3D G3DSA:3.30.70.790 49 71 0.098 T 29-03-2018 CB4_RS18030 1cb056d0679fc7dc442850eb339bacff 203 Gene3D G3DSA:3.40.50.620 34 170 4.4E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS18030 1cb056d0679fc7dc442850eb339bacff 203 Pfam PF02698 DUF218 domain 45 171 8.0E-27 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CB4_RS05775 f13c3301540200f03297dfbabb82c9b0 254 Pfam PF01478 Type IV leader peptidase family 105 209 5.4E-19 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CB4_RS05775 f13c3301540200f03297dfbabb82c9b0 254 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 166 176 3.1E-7 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CB4_RS05775 f13c3301540200f03297dfbabb82c9b0 254 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 177 188 3.1E-7 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CB4_RS05775 f13c3301540200f03297dfbabb82c9b0 254 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 113 130 3.1E-7 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CB4_RS05775 f13c3301540200f03297dfbabb82c9b0 254 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 189 204 3.1E-7 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CB4_RS05775 f13c3301540200f03297dfbabb82c9b0 254 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 11 92 4.0E-29 T 29-03-2018 IPR010627 Peptidase A24A, N-terminal CB4_RS02820 3d6079062b52fb83e38849d1dd87c40b 322 SUPERFAMILY SSF56655 1 313 6.71E-116 T 29-03-2018 CB4_RS02820 3d6079062b52fb83e38849d1dd87c40b 322 Gene3D G3DSA:3.30.540.10 155 322 2.0E-61 T 29-03-2018 CB4_RS02820 3d6079062b52fb83e38849d1dd87c40b 322 Gene3D G3DSA:3.30.540.10 1 154 1.5E-59 T 29-03-2018 CB4_RS02820 3d6079062b52fb83e38849d1dd87c40b 322 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 321 2.7E-147 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CB4_RS02820 3d6079062b52fb83e38849d1dd87c40b 322 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 310 6.6E-148 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CB4_RS02820 3d6079062b52fb83e38849d1dd87c40b 322 PIRSF PIRSF004532 1 321 1.4E-155 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CB4_RS10075 0bb702c70c622118c8fae6759ca29490 398 Pfam PF12704 MacB-like periplasmic core domain 22 242 3.3E-30 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CB4_RS10075 0bb702c70c622118c8fae6759ca29490 398 Pfam PF02687 FtsX-like permease family 305 391 3.1E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CB4_RS18855 54211f929abd1fdd7e66ba85b3a54a84 51 Pfam PF07561 Domain of Unknown Function (DUF1540) 5 47 2.3E-15 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 CB4_RS08270 cddfaa0086ca8a1bcae9b25130e431e0 259 Pfam PF08478 POTRA domain, FtsQ-type 45 113 1.4E-13 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type CB4_RS08270 cddfaa0086ca8a1bcae9b25130e431e0 259 Hamap MF_00912 Cell division protein DivIB [divIB]. 1 249 24.21 T 29-03-2018 IPR026580 Cell division protein DivIB CB4_RS08270 cddfaa0086ca8a1bcae9b25130e431e0 259 Pfam PF03799 Cell division protein FtsQ 118 226 5.0E-5 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB CB4_RS00950 575800f3e0d4e38a950b8c7f91216d93 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 1.3E-82 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00950 575800f3e0d4e38a950b8c7f91216d93 207 Gene3D G3DSA:3.40.1370.10 147 205 2.3E-17 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CB4_RS00950 575800f3e0d4e38a950b8c7f91216d93 207 Gene3D G3DSA:3.40.1370.10 2 146 6.0E-58 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CB4_RS00950 575800f3e0d4e38a950b8c7f91216d93 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 37.171 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CB4_RS00950 575800f3e0d4e38a950b8c7f91216d93 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 6.0E-74 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CB4_RS00950 575800f3e0d4e38a950b8c7f91216d93 207 SUPERFAMILY SSF52166 1 206 1.83E-84 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CB4_RS09660 ddc9fb4591b24deaac4a34b8db774a42 215 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 11 211 2.9E-67 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CB4_RS09660 ddc9fb4591b24deaac4a34b8db774a42 215 Pfam PF03006 Haemolysin-III related 8 204 4.2E-41 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CB4_RS12050 cf482db67a161b9c4700c6d283bda9b7 74 SUPERFAMILY SSF54236 7 69 4.4E-6 T 29-03-2018 IPR029071 Ubiquitin-related domain CB4_RS12050 cf482db67a161b9c4700c6d283bda9b7 74 Gene3D G3DSA:3.10.20.90 4 73 2.9E-4 T 29-03-2018 CB4_RS04165 3cfd588bf50da342a8cbf284a42fa0fc 217 SUPERFAMILY SSF50685 146 204 3.49E-9 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CB4_RS04165 3cfd588bf50da342a8cbf284a42fa0fc 217 Pfam PF06725 3D domain 155 213 2.8E-17 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CB4_RS04165 3cfd588bf50da342a8cbf284a42fa0fc 217 Gene3D G3DSA:2.40.40.10 39 216 3.7E-34 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CB4_RS09915 5dc7e2da1ef2d03f7afb0cb5f711b0a3 301 Gene3D G3DSA:3.40.830.10 2 285 4.8E-38 T 29-03-2018 CB4_RS09915 5dc7e2da1ef2d03f7afb0cb5f711b0a3 301 SUPERFAMILY SSF53213 7 284 7.46E-37 T 29-03-2018 CB4_RS09915 5dc7e2da1ef2d03f7afb0cb5f711b0a3 301 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 282 1.8E-28 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CB4_RS03120 baba5a1aaaa1c347253d7bc38430626d 248 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 62 228 1.7E-61 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CB4_RS03120 baba5a1aaaa1c347253d7bc38430626d 248 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 5 243 55.832 T 29-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 CB4_RS03120 baba5a1aaaa1c347253d7bc38430626d 248 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 58 234 1.8E-54 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CB4_RS02375 ad42c1d0e4dd3f7d75a30eb7477cfec8 298 SMART SM00283 123 298 4.0E-4 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02375 ad42c1d0e4dd3f7d75a30eb7477cfec8 298 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 145 291 4.3E-24 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CB4_RS02375 ad42c1d0e4dd3f7d75a30eb7477cfec8 298 Gene3D G3DSA:1.10.287.950 130 296 2.5E-35 T 29-03-2018 CB4_RS02375 ad42c1d0e4dd3f7d75a30eb7477cfec8 298 SUPERFAMILY SSF58104 133 291 9.29E-39 T 29-03-2018 CB4_RS13750 a99bce20a8e5282eebdf61612eaf4deb 257 Gene3D G3DSA:3.40.50.720 2 252 1.1E-58 T 29-03-2018 CB4_RS13750 a99bce20a8e5282eebdf61612eaf4deb 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 1.4E-48 T 29-03-2018 CB4_RS13750 a99bce20a8e5282eebdf61612eaf4deb 257 SUPERFAMILY SSF51735 7 251 1.99E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS13750 a99bce20a8e5282eebdf61612eaf4deb 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS13750 a99bce20a8e5282eebdf61612eaf4deb 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS13750 a99bce20a8e5282eebdf61612eaf4deb 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS13750 a99bce20a8e5282eebdf61612eaf4deb 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS13750 a99bce20a8e5282eebdf61612eaf4deb 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS13750 a99bce20a8e5282eebdf61612eaf4deb 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS03880 8feccd1a8a4a9e9fc2e1ec744c0c6566 144 Pfam PF01475 Ferric uptake regulator family 16 124 4.9E-25 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CB4_RS03880 8feccd1a8a4a9e9fc2e1ec744c0c6566 144 SUPERFAMILY SSF46785 10 134 1.17E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS03880 8feccd1a8a4a9e9fc2e1ec744c0c6566 144 Gene3D G3DSA:1.10.10.10 9 91 3.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS10980 a4510c3181549037cd0ad770c7bf4c5c 290 Pfam PF01522 Polysaccharide deacetylase 86 220 6.5E-17 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS10980 a4510c3181549037cd0ad770c7bf4c5c 290 SUPERFAMILY SSF88713 60 286 1.14E-33 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS10980 a4510c3181549037cd0ad770c7bf4c5c 290 Gene3D G3DSA:3.20.20.370 55 285 1.0E-29 T 29-03-2018 CB4_RS08170 e46b6ae883dfe0a90cf92bf0237ce5f2 253 SUPERFAMILY SSF52096 1 253 2.34E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS08170 e46b6ae883dfe0a90cf92bf0237ce5f2 253 Gene3D G3DSA:3.90.226.10 1 253 3.4E-67 T 29-03-2018 CB4_RS08170 e46b6ae883dfe0a90cf92bf0237ce5f2 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 214 1.2E-42 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CB4_RS12720 cfd9563bc57238792d0531af333dd4c1 364 Pfam PF16113 Enoyl-CoA hydratase/isomerase 17 350 2.1E-124 T 29-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CB4_RS12720 cfd9563bc57238792d0531af333dd4c1 364 Gene3D G3DSA:3.90.226.10 1 344 1.2E-86 T 29-03-2018 CB4_RS12720 cfd9563bc57238792d0531af333dd4c1 364 SUPERFAMILY SSF52096 260 336 1.16E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS12720 cfd9563bc57238792d0531af333dd4c1 364 SUPERFAMILY SSF52096 6 191 1.16E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CB4_RS13020 9fcf870aed09a99bfdfd4752212b8353 92 SMART SM00418 12 91 1.2E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13020 9fcf870aed09a99bfdfd4752212b8353 92 Gene3D G3DSA:1.10.10.10 1 89 1.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13020 9fcf870aed09a99bfdfd4752212b8353 92 SUPERFAMILY SSF46785 5 89 3.58E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS13020 9fcf870aed09a99bfdfd4752212b8353 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 4.0E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13020 9fcf870aed09a99bfdfd4752212b8353 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 4.0E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13020 9fcf870aed09a99bfdfd4752212b8353 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 4.0E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CB4_RS13020 9fcf870aed09a99bfdfd4752212b8353 92 Pfam PF12840 Helix-turn-helix domain 12 70 6.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS17400 27c88d9311bb4abb3c9aff0e235e35b4 143 Gene3D G3DSA:3.10.580.10 1 71 2.2E-19 T 29-03-2018 CB4_RS17400 27c88d9311bb4abb3c9aff0e235e35b4 143 Gene3D G3DSA:3.10.580.10 72 139 3.1E-14 T 29-03-2018 CB4_RS17400 27c88d9311bb4abb3c9aff0e235e35b4 143 SUPERFAMILY SSF54631 5 118 5.05E-37 T 29-03-2018 CB4_RS17400 27c88d9311bb4abb3c9aff0e235e35b4 143 Pfam PF00571 CBS domain 7 54 3.9E-16 T 29-03-2018 IPR000644 CBS domain CB4_RS17400 27c88d9311bb4abb3c9aff0e235e35b4 143 Pfam PF00571 CBS domain 69 119 6.0E-13 T 29-03-2018 IPR000644 CBS domain CB4_RS17400 27c88d9311bb4abb3c9aff0e235e35b4 143 SMART SM00116 76 123 3.6E-10 T 29-03-2018 IPR000644 CBS domain CB4_RS17400 27c88d9311bb4abb3c9aff0e235e35b4 143 SMART SM00116 12 59 3.6E-12 T 29-03-2018 IPR000644 CBS domain CB4_RS15280 2baa8ad4bd67477cc632af198fd5d159 232 PIRSF PIRSF016933 1 223 7.4E-76 T 29-03-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 CB4_RS15280 2baa8ad4bd67477cc632af198fd5d159 232 Pfam PF13367 Protease prsW family 28 203 6.0E-35 T 29-03-2018 IPR026898 Protease PrsW GO:0008233 CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 SUPERFAMILY SSF63829 41 308 3.6E-36 T 29-03-2018 CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Pfam PF01436 NHL repeat 107 133 1.2E-5 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Pfam PF01436 NHL repeat 189 216 9.3E-5 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Pfam PF01436 NHL repeat 60 87 6.7E-8 T 29-03-2018 IPR001258 NHL repeat GO:0005515 CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Gene3D G3DSA:2.120.10.30 179 958 6.1E-22 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Gene3D G3DSA:2.120.10.30 38 178 7.3E-23 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Pfam PF07532 Bacterial Ig-like domain (group 4) 622 676 3.5E-6 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Pfam PF07532 Bacterial Ig-like domain (group 4) 331 387 2.8E-6 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Pfam PF07532 Bacterial Ig-like domain (group 4) 429 485 3.0E-6 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Pfam PF07532 Bacterial Ig-like domain (group 4) 527 583 1.1E-6 T 29-03-2018 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Pfam PF00395 S-layer homology domain 959 1000 2.8E-8 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Pfam PF00395 S-layer homology domain 1017 1059 3.3E-15 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18810 a0adb3efd8ddb89338c7b1ec76f087c6 1144 Pfam PF00395 S-layer homology domain 1090 1131 8.8E-6 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS11635 54f7bae0177ffdd6309f128810730369 281 Gene3D G3DSA:1.10.150.130 2 104 4.7E-23 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CB4_RS11635 54f7bae0177ffdd6309f128810730369 281 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 84 4.8E-17 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CB4_RS11635 54f7bae0177ffdd6309f128810730369 281 SUPERFAMILY SSF56349 7 270 1.06E-57 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS11635 54f7bae0177ffdd6309f128810730369 281 Pfam PF00589 Phage integrase family 109 265 4.5E-40 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS11635 54f7bae0177ffdd6309f128810730369 281 Gene3D G3DSA:1.10.443.10 105 281 9.2E-42 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS11610 5478a1ad4311b11f0268c7cd02695d5a 103 Gene3D G3DSA:3.90.230.10 10 102 6.8E-4 T 29-03-2018 CB4_RS03240 38e075167099c464d97f5a9c789be54d 457 Pfam PF02397 Bacterial sugar transferase 255 436 8.9E-68 T 29-03-2018 IPR003362 Bacterial sugar transferase CB4_RS03240 38e075167099c464d97f5a9c789be54d 457 Gene3D G3DSA:3.40.50.720 125 242 2.9E-4 T 29-03-2018 CB4_RS03240 38e075167099c464d97f5a9c789be54d 457 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 17 440 2.1E-120 T 29-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CB4_RS11335 d45d616c45b5f21baa30f06a9fbaf749 246 PIRSF PIRSF000398 1 240 3.7E-36 T 29-03-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 CB4_RS11335 d45d616c45b5f21baa30f06a9fbaf749 246 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 3 215 5.9E-18 T 29-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CB4_RS11335 d45d616c45b5f21baa30f06a9fbaf749 246 SUPERFAMILY SSF53335 2 237 1.31E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS11335 d45d616c45b5f21baa30f06a9fbaf749 246 Gene3D G3DSA:3.40.50.150 1 244 6.1E-27 T 29-03-2018 CB4_RS15035 b5edd0cca470b358c471e71ff203fba5 288 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 51 283 4.0E-47 T 29-03-2018 IPR014231 Sporulation protein YpjB CB4_RS15260 30e12504223e67f1e232283aafa225bb 202 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 24 148 1.7E-31 T 29-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 CB4_RS15260 30e12504223e67f1e232283aafa225bb 202 SUPERFAMILY SSF69593 5 199 6.8E-50 T 29-03-2018 CB4_RS15260 30e12504223e67f1e232283aafa225bb 202 Pfam PF01553 Acyltransferase 24 148 1.8E-24 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CB4_RS15260 30e12504223e67f1e232283aafa225bb 202 SMART SM00563 37 151 1.8E-33 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CB4_RS15260 30e12504223e67f1e232283aafa225bb 202 Gene3D G3DSA:3.40.1130.10 2 202 5.8E-42 T 29-03-2018 CB4_RS19420 13cef503b8047cf60b771ddf23cb2461 476 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 5 462 1.4E-145 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS19420 13cef503b8047cf60b771ddf23cb2461 476 PIRSF PIRSF005690 1 476 6.9E-140 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CB4_RS19290 a0077f78fdaf54ea96b83fe218a84aca 226 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 11 222 1.2E-55 T 29-03-2018 IPR006214 Bax inhibitor 1-related CB4_RS04060 ee2a1c8eb6b084efff8f8c0a5b41c846 203 Pfam PF00293 NUDIX domain 24 135 5.5E-14 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CB4_RS04060 ee2a1c8eb6b084efff8f8c0a5b41c846 203 Gene3D G3DSA:3.90.79.10 1 203 1.3E-36 T 29-03-2018 CB4_RS04060 ee2a1c8eb6b084efff8f8c0a5b41c846 203 SUPERFAMILY SSF55811 21 195 1.49E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CB4_RS09145 c8ed5ad3c45a7d40359982e0b03c922d 155 Pfam PF03748 Flagellar basal body-associated protein FliL 63 150 1.2E-9 T 29-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 CB4_RS16400 2d3da7de145dbea1d798f8b4351ec7c5 270 Pfam PF00953 Glycosyl transferase family 4 72 225 8.8E-5 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CB4_RS00300 bd162313dfbf590ad9bacf4bdee6cd2c 522 Pfam PF00474 Sodium:solute symporter family 36 458 2.5E-72 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CB4_RS00300 bd162313dfbf590ad9bacf4bdee6cd2c 522 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 36 458 6.1E-57 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CB4_RS06805 1f6c7aebe3315cbd92b0e7631253b1ec 208 Gene3D G3DSA:3.40.1000.10 48 205 4.6E-14 T 29-03-2018 CB4_RS10875 f494d4c397341aeed29aa955090ba0fc 143 Pfam PF01575 MaoC like domain 14 122 9.3E-22 T 29-03-2018 IPR002539 MaoC-like domain CB4_RS10875 f494d4c397341aeed29aa955090ba0fc 143 SUPERFAMILY SSF54637 10 142 9.86E-30 T 29-03-2018 IPR029069 HotDog domain CB4_RS10875 f494d4c397341aeed29aa955090ba0fc 143 Gene3D G3DSA:3.10.129.10 7 142 8.7E-32 T 29-03-2018 CB4_RS03440 d50040ca30a7dfbc097691efb64c4b40 257 Gene3D G3DSA:1.10.287.70 95 206 7.7E-5 T 29-03-2018 CB4_RS09730 4a849c20961b244b71cdda9972499a93 261 Pfam PF01925 Sulfite exporter TauE/SafE 9 253 1.3E-40 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CB4_RS10095 2790c6e8f54bd9f544c5271cf7184504 129 Pfam PF10710 Protein of unknown function (DUF2512) 1 117 1.9E-17 T 29-03-2018 IPR019649 Protein of unknown function DUF2512 CB4_RS16065 1ecffffabf117e6eea8eb88bd1426e5e 712 Gene3D G3DSA:3.40.50.300 236 379 8.5E-24 T 29-03-2018 CB4_RS16065 1ecffffabf117e6eea8eb88bd1426e5e 712 Gene3D G3DSA:3.40.50.300 3 235 1.2E-36 T 29-03-2018 CB4_RS16065 1ecffffabf117e6eea8eb88bd1426e5e 712 SUPERFAMILY SSF52540 33 361 1.53E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS16065 1ecffffabf117e6eea8eb88bd1426e5e 712 Pfam PF00270 DEAD/DEAH box helicase 25 198 3.2E-32 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CB4_RS16065 1ecffffabf117e6eea8eb88bd1426e5e 712 Pfam PF00271 Helicase conserved C-terminal domain 246 354 1.1E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS16065 1ecffffabf117e6eea8eb88bd1426e5e 712 SMART SM00490 270 355 2.0E-13 T 29-03-2018 IPR001650 Helicase, C-terminal CB4_RS16065 1ecffffabf117e6eea8eb88bd1426e5e 712 SMART SM00487 20 227 6.5E-33 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CB4_RS17645 2329a86a5e3daa7eaf9fe53a4f7361f7 283 Gene3D G3DSA:1.25.40.290 172 283 2.8E-17 T 29-03-2018 CB4_RS17645 2329a86a5e3daa7eaf9fe53a4f7361f7 283 Pfam PF08713 DNA alkylation repair enzyme 173 253 1.3E-6 T 29-03-2018 IPR014825 DNA alkylation repair enzyme CB4_RS17645 2329a86a5e3daa7eaf9fe53a4f7361f7 283 SUPERFAMILY SSF48371 101 281 6.28E-32 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CB4_RS15640 f75a0141619fd9f89cb048d5d1590149 163 Pfam PF13158 Protein of unknown function (DUF3993) 26 132 2.4E-10 T 29-03-2018 IPR025056 Protein of unknown function DUF3993 CB4_RS01955 b99b60053913cfe07e4c4621adcf593e 253 Pfam PF13614 AAA domain 2 177 5.6E-71 T 29-03-2018 IPR025669 AAA domain CB4_RS01955 b99b60053913cfe07e4c4621adcf593e 253 SUPERFAMILY SSF52540 1 251 3.48E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS01955 b99b60053913cfe07e4c4621adcf593e 253 Gene3D G3DSA:3.40.50.300 1 252 1.1E-62 T 29-03-2018 CB4_RS01955 b99b60053913cfe07e4c4621adcf593e 253 PIRSF PIRSF009320 2 65 8.5E-16 T 29-03-2018 CB4_RS01955 b99b60053913cfe07e4c4621adcf593e 253 PIRSF PIRSF009320 90 252 1.6E-9 T 29-03-2018 CB4_RS00515 2ad8079d5a60e3b6ea6a48bf70455850 476 PIRSF PIRSF006060 1 471 2.4E-85 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS00515 2ad8079d5a60e3b6ea6a48bf70455850 476 Pfam PF00324 Amino acid permease 17 456 8.0E-126 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CB4_RS00515 2ad8079d5a60e3b6ea6a48bf70455850 476 ProSitePatterns PS00218 Amino acid permeases signature. 42 73 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CB4_RS01235 ea1805d224d9d38e772ff678e21c8caa 159 Pfam PF02559 CarD-like/TRCF domain 2 110 1.2E-21 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS01235 ea1805d224d9d38e772ff678e21c8caa 159 SMART SM01058 1 111 3.1E-38 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS01235 ea1805d224d9d38e772ff678e21c8caa 159 SUPERFAMILY SSF141259 2 62 7.32E-14 T 29-03-2018 IPR003711 CarD-like/TRCF domain CB4_RS07940 8f658f3fb7cc2578f2466e3cf8a113fe 134 Pfam PF03780 Asp23 family, cell envelope-related function 12 116 1.5E-32 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 CB4_RS12985 6c01fcebefe9c44b075de87c65717b69 286 Pfam PF07486 Cell Wall Hydrolase 178 284 8.2E-21 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CB4_RS12985 6c01fcebefe9c44b075de87c65717b69 286 Pfam PF07833 Copper amine oxidase N-terminal domain 45 140 9.4E-13 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS12985 6c01fcebefe9c44b075de87c65717b69 286 Pfam PF07833 Copper amine oxidase N-terminal domain 113 144 1.3E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS12985 6c01fcebefe9c44b075de87c65717b69 286 Gene3D G3DSA:3.30.457.10 54 123 1.3E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS12985 6c01fcebefe9c44b075de87c65717b69 286 Gene3D G3DSA:3.30.457.10 124 281 7.4E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS12985 6c01fcebefe9c44b075de87c65717b69 286 Gene3D G3DSA:3.30.457.10 16 53 0.023 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS12985 6c01fcebefe9c44b075de87c65717b69 286 SUPERFAMILY SSF55383 48 135 1.96E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS07020 90b83c5876eb6d7018fe9fa4a3187a3d 416 Pfam PF04286 Protein of unknown function (DUF445) 40 412 6.3E-74 T 29-03-2018 IPR007383 Protein of unknown function DUF445 CB4_RS04135 ce691d2fbc3e046d7dba39411877af11 266 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS04135 ce691d2fbc3e046d7dba39411877af11 266 SUPERFAMILY SSF52540 2 234 2.1E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS04135 ce691d2fbc3e046d7dba39411877af11 266 SMART SM00382 27 220 1.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS04135 ce691d2fbc3e046d7dba39411877af11 266 Pfam PF00005 ABC transporter 18 169 2.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS04135 ce691d2fbc3e046d7dba39411877af11 266 Gene3D G3DSA:3.40.50.300 1 247 4.7E-54 T 29-03-2018 CB4_RS12410 c7d56c3b709e587d8ca09a09745f2fba 712 Gene3D G3DSA:2.60.40.10 352 448 2.5E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold CB4_RS12410 c7d56c3b709e587d8ca09a09745f2fba 712 Pfam PF00395 S-layer homology domain 153 194 4.4E-10 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS12410 c7d56c3b709e587d8ca09a09745f2fba 712 Pfam PF00395 S-layer homology domain 91 134 2.8E-7 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS12410 c7d56c3b709e587d8ca09a09745f2fba 712 Pfam PF00395 S-layer homology domain 33 72 6.3E-11 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS18445 68a4a948d782c953f9a722cefba38f45 105 Pfam PF14034 Sporulation protein YtrH 4 101 6.8E-34 T 29-03-2018 IPR025689 Sporulation protein YtrH CB4_RS20675 62334ed959d3787bfb00f45ede5df4b1 311 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 69 218 1.3E-48 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CB4_RS20675 62334ed959d3787bfb00f45ede5df4b1 311 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 69 218 7.6E-44 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CB4_RS05665 e969a4c096c1669d79d1ba49283cdee4 273 Pfam PF01578 Cytochrome C assembly protein 66 267 1.7E-32 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CB4_RS19355 b8f7a8559b4f3d47d763ccff11de3d27 360 Pfam PF01384 Phosphate transporter family 18 311 4.5E-42 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CB4_RS12690 50871be5a3cdac59a933556868c6ead3 149 Gene3D G3DSA:3.40.190.10 1 144 2.1E-4 T 29-03-2018 CB4_RS14520 711092ee163d0b3130e9c3f1f63a994f 137 Pfam PF06271 RDD family 9 129 2.8E-18 T 29-03-2018 IPR010432 RDD CB4_RS20660 bcf7d34a320a80dad145c1e56ac0f143 267 Pfam PF00691 OmpA family 134 233 6.3E-19 T 29-03-2018 IPR006665 OmpA-like domain CB4_RS20660 bcf7d34a320a80dad145c1e56ac0f143 267 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 55 6.5E-21 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain CB4_RS20660 bcf7d34a320a80dad145c1e56ac0f143 267 SUPERFAMILY SSF103088 122 239 1.14E-30 T 29-03-2018 IPR006665 OmpA-like domain CB4_RS20660 bcf7d34a320a80dad145c1e56ac0f143 267 Gene3D G3DSA:3.30.1330.60 81 267 9.1E-44 T 29-03-2018 IPR006665 OmpA-like domain CB4_RS09610 e2a14835e1c11e672c91b031bef5282f 486 Gene3D G3DSA:3.90.1300.10 3 484 5.6E-118 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS09610 e2a14835e1c11e672c91b031bef5282f 486 ProSitePatterns PS00571 Amidases signature. 149 180 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CB4_RS09610 e2a14835e1c11e672c91b031bef5282f 486 Pfam PF01425 Amidase 27 457 1.6E-90 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS09610 e2a14835e1c11e672c91b031bef5282f 486 SUPERFAMILY SSF75304 4 467 1.96E-116 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CB4_RS13840 4be20b7e5f0297be68b5abfde42986e7 215 Pfam PF00881 Nitroreductase family 10 194 1.3E-36 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CB4_RS13840 4be20b7e5f0297be68b5abfde42986e7 215 Gene3D G3DSA:3.40.109.10 3 215 2.3E-46 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS13840 4be20b7e5f0297be68b5abfde42986e7 215 SUPERFAMILY SSF55469 6 66 9.16E-50 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS13840 4be20b7e5f0297be68b5abfde42986e7 215 SUPERFAMILY SSF55469 95 213 9.16E-50 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS05210 6904907d3016e50cca8ca7573e58609c 174 SMART SM00267 1 168 3.3E-63 T 29-03-2018 IPR000160 GGDEF domain CB4_RS05210 6904907d3016e50cca8ca7573e58609c 174 Gene3D G3DSA:3.30.70.270 1 174 5.0E-56 T 29-03-2018 CB4_RS05210 6904907d3016e50cca8ca7573e58609c 174 Pfam PF00990 Diguanylate cyclase, GGDEF domain 4 164 1.8E-53 T 29-03-2018 IPR000160 GGDEF domain CB4_RS05210 6904907d3016e50cca8ca7573e58609c 174 SUPERFAMILY SSF55073 8 169 9.42E-53 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS05210 6904907d3016e50cca8ca7573e58609c 174 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 2 166 1.3E-55 T 29-03-2018 IPR000160 GGDEF domain CB4_RS12495 50be6ffd06f631386d0a340ac324bc83 365 Pfam PF02687 FtsX-like permease family 273 356 2.2E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CB4_RS18035 0f0ca841b1cac349c3756f411fb7bbd4 230 Pfam PF02589 LUD domain 49 228 2.4E-33 T 29-03-2018 IPR003741 LUD domain CB4_RS18035 0f0ca841b1cac349c3756f411fb7bbd4 230 SUPERFAMILY SSF100950 43 228 5.86E-40 T 29-03-2018 CB4_RS18035 0f0ca841b1cac349c3756f411fb7bbd4 230 Gene3D G3DSA:3.40.50.10420 41 229 5.0E-43 T 29-03-2018 CB4_RS16500 2b0ee4ffb3ec2b5f85346f4dea40eec9 202 Gene3D G3DSA:1.20.144.10 13 187 4.8E-30 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS16500 2b0ee4ffb3ec2b5f85346f4dea40eec9 202 Pfam PF01569 PAP2 superfamily 62 170 1.4E-20 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS16500 2b0ee4ffb3ec2b5f85346f4dea40eec9 202 SMART SM00014 57 165 1.1E-21 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS16500 2b0ee4ffb3ec2b5f85346f4dea40eec9 202 SUPERFAMILY SSF48317 2 172 2.75E-41 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CB4_RS04770 03f0b913fe4271d752478400089c5d13 275 Pfam PF01925 Sulfite exporter TauE/SafE 10 268 7.8E-55 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CB4_RS07920 2b38dea5268d751581867ce4e51af765 170 Gene3D G3DSA:3.40.50.40 107 161 6.6E-4 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CB4_RS07920 2b38dea5268d751581867ce4e51af765 170 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 3 169 2.1E-50 T 29-03-2018 IPR014195 Sporulation stage III, protein AG CB4_RS09365 a033ca6778fc16e055039ce1cf2c1c0e 329 Gene3D G3DSA:3.20.20.370 97 326 1.1E-51 T 29-03-2018 CB4_RS09365 a033ca6778fc16e055039ce1cf2c1c0e 329 Pfam PF01522 Polysaccharide deacetylase 134 255 9.5E-31 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CB4_RS09365 a033ca6778fc16e055039ce1cf2c1c0e 329 SUPERFAMILY SSF88713 120 320 8.9E-59 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CB4_RS09230 3d519933da4b9619b644734189a0c86b 160 SUPERFAMILY SSF64438 3 158 7.51E-50 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CB4_RS09230 3d519933da4b9619b644734189a0c86b 160 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 5 156 26.277 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CB4_RS09230 3d519933da4b9619b644734189a0c86b 160 Pfam PF03975 CheD chemotactic sensory transduction 47 152 3.6E-36 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CB4_RS14490 1b2ac980f542528c7ecb949f4286e716 62 Pfam PF13076 Fur-regulated basic protein A 18 41 3.5E-8 T 29-03-2018 IPR025072 Fur-regulated basic protein A CB4_RS16020 c5604915d9ec44a1bc1a6fde8c37dd49 212 Pfam PF02163 Peptidase family M50 126 168 1.1E-8 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CB4_RS17880 101256ca79e2a59f5a8b35f10e8d21a0 321 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 17 316 1.6E-126 T 29-03-2018 IPR005911 Protein YhcC-like GO:0051536 CB4_RS17880 101256ca79e2a59f5a8b35f10e8d21a0 321 Gene3D G3DSA:3.20.20.70 15 302 1.9E-39 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS17880 101256ca79e2a59f5a8b35f10e8d21a0 321 Pfam PF16199 Radical_SAM C-terminal domain 222 304 6.2E-24 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CB4_RS17880 101256ca79e2a59f5a8b35f10e8d21a0 321 SUPERFAMILY SSF102114 8 315 6.02E-56 T 29-03-2018 CB4_RS17880 101256ca79e2a59f5a8b35f10e8d21a0 321 Pfam PF04055 Radical SAM superfamily 54 216 9.9E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CB4_RS17880 101256ca79e2a59f5a8b35f10e8d21a0 321 SMART SM00729 34 261 1.1E-43 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CB4_RS20225 dc25fca8af2af66fc7249aa239ea05fa 136 Pfam PF07681 DoxX 8 87 1.8E-17 T 29-03-2018 IPR032808 DoxX family CB4_RS01795 0051dd0c006fee8c58bebdcfcd46897e 259 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 250 8.0E-76 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CB4_RS01795 0051dd0c006fee8c58bebdcfcd46897e 259 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 245 2.0E-61 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CB4_RS01795 0051dd0c006fee8c58bebdcfcd46897e 259 Gene3D G3DSA:3.40.50.2300 2 127 5.7E-6 T 29-03-2018 CB4_RS01795 0051dd0c006fee8c58bebdcfcd46897e 259 Gene3D G3DSA:3.40.50.2300 134 257 1.5E-6 T 29-03-2018 CB4_RS02320 9ce07da705f69be4bc37d333de02b937 302 Gene3D G3DSA:1.10.3470.10 1 273 2.3E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS02320 9ce07da705f69be4bc37d333de02b937 302 Pfam PF02653 Branched-chain amino acid transport system / permease component 1 268 6.6E-38 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS04870 9913266998a43f82e2864e710f29e51b 282 Pfam PF12679 ABC-2 family transporter protein 12 273 4.2E-8 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CB4_RS03500 4fdb4ba2d1c1d693291580638bd8a517 65 PRINTS PR00050 Cold shock protein signature 38 56 1.1E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS03500 4fdb4ba2d1c1d693291580638bd8a517 65 PRINTS PR00050 Cold shock protein signature 23 32 1.1E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS03500 4fdb4ba2d1c1d693291580638bd8a517 65 PRINTS PR00050 Cold shock protein signature 3 18 1.1E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS03500 4fdb4ba2d1c1d693291580638bd8a517 65 SUPERFAMILY SSF50249 1 64 7.37E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CB4_RS03500 4fdb4ba2d1c1d693291580638bd8a517 65 Pfam PF00313 'Cold-shock' DNA-binding domain 1 64 1.5E-32 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CB4_RS03500 4fdb4ba2d1c1d693291580638bd8a517 65 Gene3D G3DSA:2.40.50.140 1 65 1.2E-27 T 29-03-2018 CB4_RS03500 4fdb4ba2d1c1d693291580638bd8a517 65 SMART SM00357 2 65 2.0E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CB4_RS03500 4fdb4ba2d1c1d693291580638bd8a517 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 32 - T 29-03-2018 IPR019844 Cold-shock conserved site CB4_RS03500 4fdb4ba2d1c1d693291580638bd8a517 65 PIRSF PIRSF002599 1 65 2.4E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CB4_RS09400 27a3c775a70953ab01df6058faabc46e 281 Gene3D G3DSA:3.60.15.10 7 280 4.4E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS09400 27a3c775a70953ab01df6058faabc46e 281 SUPERFAMILY SSF56281 29 273 1.57E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS09400 27a3c775a70953ab01df6058faabc46e 281 SMART SM00849 33 268 4.7E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS09400 27a3c775a70953ab01df6058faabc46e 281 Pfam PF00753 Metallo-beta-lactamase superfamily 43 252 2.7E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CB4_RS15245 3e5d2936cba143d20a6a04f6ecdc819d 302 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 7 291 4.0E-95 T 29-03-2018 CB4_RS15245 3e5d2936cba143d20a6a04f6ecdc819d 302 Pfam PF14045 YIEGIA protein 12 291 2.8E-119 T 29-03-2018 IPR025918 YIEGIA protein CB4_RS12685 1a51d5e1a15b1566749a82fa7e20ebf0 500 Pfam PF03239 Iron permease FTR1 family 223 353 1.1E-14 T 29-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 CB4_RS10925 5baa1e3b036a049e032bae711d98cd6a 269 Pfam PF03824 High-affinity nickel-transport protein 5 191 3.5E-12 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CB4_RS12975 39e01bc9dd153000baed7d4e97c2833c 232 Pfam PF03591 AzlC protein 17 157 9.9E-39 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease CB4_RS15955 ce52808203652fe4fa526c1823870c14 405 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 55 405 1.2E-76 T 29-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CB4_RS15955 ce52808203652fe4fa526c1823870c14 405 Pfam PF01578 Cytochrome C assembly protein 90 402 1.7E-37 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CB4_RS02735 f703ca0b738b2d47e1f6d5e25dfade11 145 SUPERFAMILY SSF50814 8 139 4.69E-23 T 29-03-2018 IPR012674 Calycin CB4_RS02735 f703ca0b738b2d47e1f6d5e25dfade11 145 Pfam PF09148 Domain of unknown function (DUF1934) 11 137 4.9E-25 T 29-03-2018 IPR015231 Protein of unknown function DUF1934 CB4_RS02735 f703ca0b738b2d47e1f6d5e25dfade11 145 Gene3D G3DSA:2.40.128.20 5 145 8.7E-32 T 29-03-2018 IPR012674 Calycin CB4_RS13895 57f77256eb4913eb8a39d62b17a42506 129 Pfam PF07681 DoxX 5 93 1.6E-22 T 29-03-2018 IPR032808 DoxX family CB4_RS16570 f7e647fa69931073a052fbdcf8229510 91 Pfam PF14149 YhfH-like protein 47 82 2.9E-15 T 29-03-2018 IPR025432 YhfH-like protein CB4_RS02405 250614ad84879a130fe4932032d2b9e7 84 Gene3D G3DSA:1.20.1480.30 4 84 0.0025 T 29-03-2018 CB4_RS10785 5cf47e9bedda1af10083af23ab5dfd53 112 Pfam PF07098 Protein of unknown function (DUF1360) 11 111 2.9E-34 T 29-03-2018 IPR010773 Mycobacterium phage PG1, Gp7 CB4_RS13130 d6e1825f9a976d48b6619f861efcca58 321 Pfam PF03239 Iron permease FTR1 family 46 161 1.0E-8 T 29-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 CB4_RS08535 04efd26c66c3b36c1c6214aec967c279 121 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 8.7E-34 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 CB4_RS07910 0e41333861a34a748f8ea29c701d6559 394 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 14 386 3.7E-128 T 29-03-2018 IPR014194 Sporulation stage III, protein AE CB4_RS07910 0e41333861a34a748f8ea29c701d6559 394 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 70 386 5.5E-103 T 29-03-2018 IPR014194 Sporulation stage III, protein AE CB4_RS10690 ef59c9b5301ed4d0d758d3132eca69bf 261 Gene3D G3DSA:3.10.50.40 123 216 2.7E-13 T 29-03-2018 CB4_RS10690 ef59c9b5301ed4d0d758d3132eca69bf 261 SUPERFAMILY SSF54534 97 214 3.01E-15 T 29-03-2018 CB4_RS10690 ef59c9b5301ed4d0d758d3132eca69bf 261 Pfam PF13616 PPIC-type PPIASE domain 137 202 2.9E-8 T 29-03-2018 CB4_RS10290 1b8d886a22b7907f8c04424372493708 148 Pfam PF00571 CBS domain 20 63 0.0019 T 29-03-2018 IPR000644 CBS domain CB4_RS10290 1b8d886a22b7907f8c04424372493708 148 Pfam PF00571 CBS domain 86 139 0.0039 T 29-03-2018 IPR000644 CBS domain CB4_RS10290 1b8d886a22b7907f8c04424372493708 148 Gene3D G3DSA:3.10.580.10 7 148 4.9E-17 T 29-03-2018 CB4_RS10290 1b8d886a22b7907f8c04424372493708 148 SUPERFAMILY SSF54631 13 140 2.07E-26 T 29-03-2018 CB4_RS19780 da844f0b173ce759ce73887f4e87b9ce 44 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 10 44 9.1E-9 T 29-03-2018 IPR009229 Staphylococcal AgrD CB4_RS02135 c7a3a2263178c9b93f447d1db6932587 364 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 7 358 3.7E-63 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS02135 c7a3a2263178c9b93f447d1db6932587 364 Pfam PF03845 Spore germination protein 7 325 1.1E-60 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS15195 f61aa82cf8f6e9e61e6014a0fe89413c 90 SMART SM00411 1 90 1.3E-48 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CB4_RS15195 f61aa82cf8f6e9e61e6014a0fe89413c 90 SUPERFAMILY SSF47729 1 89 8.68E-34 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CB4_RS15195 f61aa82cf8f6e9e61e6014a0fe89413c 90 Pfam PF00216 Bacterial DNA-binding protein 1 89 1.3E-36 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CB4_RS15195 f61aa82cf8f6e9e61e6014a0fe89413c 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.6E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CB4_RS15195 f61aa82cf8f6e9e61e6014a0fe89413c 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.6E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CB4_RS15195 f61aa82cf8f6e9e61e6014a0fe89413c 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.6E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CB4_RS15195 f61aa82cf8f6e9e61e6014a0fe89413c 90 Gene3D G3DSA:4.10.520.10 1 90 1.6E-37 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CB4_RS15195 f61aa82cf8f6e9e61e6014a0fe89413c 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CB4_RS20165 6b88e9b17f5c62e32fa39f26fe4e0242 488 SUPERFAMILY SSF56176 3 216 3.04E-71 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CB4_RS20165 6b88e9b17f5c62e32fa39f26fe4e0242 488 Gene3D G3DSA:3.30.465.10 93 238 2.9E-39 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CB4_RS20165 6b88e9b17f5c62e32fa39f26fe4e0242 488 SUPERFAMILY SSF55103 219 458 6.7E-68 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CB4_RS20165 6b88e9b17f5c62e32fa39f26fe4e0242 488 Gene3D G3DSA:1.10.45.10 417 456 7.6E-18 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CB4_RS20165 6b88e9b17f5c62e32fa39f26fe4e0242 488 Gene3D G3DSA:3.30.43.10 2 92 1.4E-24 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CB4_RS20165 6b88e9b17f5c62e32fa39f26fe4e0242 488 Pfam PF01565 FAD binding domain 40 179 3.0E-41 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CB4_RS20165 6b88e9b17f5c62e32fa39f26fe4e0242 488 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 456 3.4E-73 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CB4_RS20130 b073ba929f71c49bcd24bc9b6b282f17 167 Pfam PF00395 S-layer homology domain 89 132 3.4E-10 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS20130 b073ba929f71c49bcd24bc9b6b282f17 167 Pfam PF00395 S-layer homology domain 28 70 3.2E-9 T 29-03-2018 IPR001119 S-layer homology domain CB4_RS11515 b9b9803b8a6db68e5af5ecc8ce8253a1 440 SUPERFAMILY SSF52980 4 162 8.22E-7 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CB4_RS11515 b9b9803b8a6db68e5af5ecc8ce8253a1 440 Gene3D G3DSA:3.40.91.20 1 188 3.6E-10 T 29-03-2018 IPR011338 Restriction endonuclease, type II, BamHI/BglIII/BstY GO:0000287|GO:0003677|GO:0009036|GO:0009307 CB4_RS20095 87babffdf66ff2aa3a9d52f370d4e4c6 180 Gene3D G3DSA:1.10.10.10 4 92 7.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS20095 87babffdf66ff2aa3a9d52f370d4e4c6 180 Pfam PF03551 Transcriptional regulator PadR-like family 7 78 5.7E-16 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CB4_RS20095 87babffdf66ff2aa3a9d52f370d4e4c6 180 SUPERFAMILY SSF46785 6 159 4.18E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS16170 012b2bc0195db00f87f5b2550c9bd165 194 Pfam PF14097 Stage V sporulation protein AE1 7 187 3.2E-74 T 29-03-2018 IPR025914 Stage V sporulation protein AE CB4_RS18605 3df8719b08e6f5557d66908ba6888dce 118 Pfam PF11750 Protein of unknown function (DUF3307) 6 112 8.7E-13 T 29-03-2018 IPR021737 Bacteriophage phiKZ, Orf197 CB4_RS04085 41d52a148ca242eae287aa6a58eb3278 160 SUPERFAMILY SSF141371 14 110 2.55E-7 T 29-03-2018 CB4_RS04085 41d52a148ca242eae287aa6a58eb3278 160 Gene3D G3DSA:2.40.10.220 13 140 2.6E-14 T 29-03-2018 CB4_RS04085 41d52a148ca242eae287aa6a58eb3278 160 Pfam PF07238 PilZ domain 18 117 6.8E-10 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CB4_RS05695 762a0a1ec62d6beb70d6b17e7e19e887 570 SUPERFAMILY SSF54106 523 568 4.19E-7 T 29-03-2018 IPR018392 LysM domain CB4_RS05695 762a0a1ec62d6beb70d6b17e7e19e887 570 SMART SM00257 523 567 1.5E-4 T 29-03-2018 IPR018392 LysM domain CB4_RS05695 762a0a1ec62d6beb70d6b17e7e19e887 570 Pfam PF01476 LysM domain 527 567 7.1E-7 T 29-03-2018 IPR018392 LysM domain CB4_RS05695 762a0a1ec62d6beb70d6b17e7e19e887 570 Gene3D G3DSA:3.10.350.10 522 570 4.2E-9 T 29-03-2018 CB4_RS13605 34fceea302936e90b4376d1af308a66a 305 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 56 277 1.0E-63 T 29-03-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 CB4_RS13605 34fceea302936e90b4376d1af308a66a 305 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 31 277 40.07 T 29-03-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 CB4_RS18945 52c0e452a75bfa1684464973d9df824e 448 Pfam PF00860 Permease family 25 409 1.1E-64 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CB4_RS06875 3da300221a5e4ee2613a59c652fa1a05 377 SUPERFAMILY SSF141571 214 371 6.02E-32 T 29-03-2018 CB4_RS06875 3da300221a5e4ee2613a59c652fa1a05 377 Pfam PF00805 Pentapeptide repeats (8 copies) 253 292 6.2E-8 T 29-03-2018 IPR001646 Pentapeptide repeat CB4_RS06875 3da300221a5e4ee2613a59c652fa1a05 377 Pfam PF00805 Pentapeptide repeats (8 copies) 318 356 3.4E-12 T 29-03-2018 IPR001646 Pentapeptide repeat CB4_RS06875 3da300221a5e4ee2613a59c652fa1a05 377 Gene3D G3DSA:2.160.20.80 191 372 2.3E-30 T 29-03-2018 CB4_RS20720 2bb4fe2d83b07d36ca87216488673c64 135 Pfam PF13581 Histidine kinase-like ATPase domain 19 126 6.7E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS15710 da3e59280ef90aba8a32baa9d540e194 240 Pfam PF13649 Methyltransferase domain 55 152 7.9E-14 T 29-03-2018 CB4_RS15710 da3e59280ef90aba8a32baa9d540e194 240 Gene3D G3DSA:3.40.50.150 13 240 2.9E-29 T 29-03-2018 CB4_RS15710 da3e59280ef90aba8a32baa9d540e194 240 SUPERFAMILY SSF53335 21 236 7.19E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS14275 a111d1a1d715812c43941d2f15f57d28 294 PIRSF PIRSF006483 4 293 6.8E-98 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS14275 a111d1a1d715812c43941d2f15f57d28 294 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 1.4E-22 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CB4_RS14275 a111d1a1d715812c43941d2f15f57d28 294 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 23 225 6.7E-69 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS19685 b23289c9d7c3a9d0697aa90514de5ee6 122 Gene3D G3DSA:3.30.450.40 5 109 8.5E-4 T 29-03-2018 IPR029016 GAF domain-like CB4_RS10110 8da9f71e978328b6fc5504dd4b67db2a 193 SUPERFAMILY SSF161111 6 192 9.42E-16 T 29-03-2018 CB4_RS10110 8da9f71e978328b6fc5504dd4b67db2a 193 Pfam PF01545 Cation efflux family 12 192 6.6E-11 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CB4_RS10110 8da9f71e978328b6fc5504dd4b67db2a 193 Gene3D G3DSA:1.20.1510.10 8 193 1.6E-8 T 29-03-2018 CB4_RS12990 a264819eb44bef2cce58defe53a3b270 116 SUPERFAMILY SSF53335 11 105 6.21E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS12990 a264819eb44bef2cce58defe53a3b270 116 Gene3D G3DSA:3.40.50.150 7 115 1.1E-7 T 29-03-2018 CB4_RS03840 e7527254827745948c35cd4b3394dec7 109 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 4 90 1.9E-16 T 29-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 CB4_RS11925 67131cee78db9fd308a9f51166b77cbf 74 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 3 64 7.4E-29 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CB4_RS11925 67131cee78db9fd308a9f51166b77cbf 74 Pfam PF17209 Hfq protein 5 68 3.3E-28 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CB4_RS11925 67131cee78db9fd308a9f51166b77cbf 74 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 64 26.023 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CB4_RS11925 67131cee78db9fd308a9f51166b77cbf 74 Gene3D G3DSA:2.30.30.100 2 73 1.3E-28 T 29-03-2018 CB4_RS11925 67131cee78db9fd308a9f51166b77cbf 74 SUPERFAMILY SSF50182 5 69 3.48E-21 T 29-03-2018 IPR010920 LSM domain CB4_RS12040 7d2c201b00cb8ef4e55c00b567c17884 98 SUPERFAMILY SSF56029 6 96 1.44E-24 T 29-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 CB4_RS12040 7d2c201b00cb8ef4e55c00b567c17884 98 Pfam PF02406 MmoB/DmpM family 10 93 6.5E-27 T 29-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 CB4_RS12040 7d2c201b00cb8ef4e55c00b567c17884 98 Gene3D G3DSA:3.90.56.10 6 96 1.2E-28 T 29-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 CB4_RS12040 7d2c201b00cb8ef4e55c00b567c17884 98 ProDom PD004249 MONOOXYGENASE COMPONENT HYDROXYLASE MMOB/DMPM PHENOL SUBUNIT 3D-STRUCTURE HYDROCARBONS IRON PHENOLHYDROXYLASE 24 85 5.0E-10 T 29-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 CB4_RS03835 e59321699bd6bbec53c9e15ba9eece02 222 Gene3D G3DSA:3.40.190.10 1 210 4.5E-5 T 29-03-2018 CB4_RS14110 6366e4283ade9d54f8207b9bf4a0b13e 62 SUPERFAMILY SSF89447 6 55 3.31E-6 T 29-03-2018 CB4_RS14110 6366e4283ade9d54f8207b9bf4a0b13e 62 Gene3D G3DSA:2.10.260.10 1 58 1.8E-6 T 29-03-2018 CB4_RS01980 7b39ef691079d87a488a0fb129f15408 86 Pfam PF11823 Protein of unknown function (DUF3343) 6 71 1.5E-17 T 29-03-2018 IPR021778 Domain of unknown function DUF3343 CB4_RS07890 3e38f42ddd080980b96d4d12985484e5 326 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 37 314 1.3E-115 T 29-03-2018 IPR014217 Sporulation stage III, protein AA CB4_RS07890 3e38f42ddd080980b96d4d12985484e5 326 Gene3D G3DSA:3.40.50.300 5 296 7.5E-9 T 29-03-2018 CB4_RS07890 3e38f42ddd080980b96d4d12985484e5 326 SUPERFAMILY SSF52540 68 284 9.25E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS07890 3e38f42ddd080980b96d4d12985484e5 326 SMART SM00382 157 295 5.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS20535 bfa91de2288e5dcba1c8fd514945fd1f 94 SUPERFAMILY SSF47598 6 50 8.01E-11 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CB4_RS20535 bfa91de2288e5dcba1c8fd514945fd1f 94 Pfam PF01402 Ribbon-helix-helix protein, copG family 10 47 2.3E-8 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CB4_RS20535 bfa91de2288e5dcba1c8fd514945fd1f 94 Gene3D G3DSA:1.10.1220.10 6 59 3.3E-17 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CB4_RS17110 9c34f59e66ada0e6dcab53b2ce835360 65 Pfam PF04070 Domain of unknown function (DUF378) 1 58 2.7E-26 T 29-03-2018 IPR007211 Protein of unknown function DUF378 CB4_RS14180 4c321b06e50edca58d5ca275a554c26a 518 Pfam PF03988 Repeat of Unknown Function (DUF347) 196 251 1.9E-16 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CB4_RS14180 4c321b06e50edca58d5ca275a554c26a 518 Pfam PF03988 Repeat of Unknown Function (DUF347) 21 72 2.8E-15 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CB4_RS14180 4c321b06e50edca58d5ca275a554c26a 518 Pfam PF03988 Repeat of Unknown Function (DUF347) 141 189 3.0E-10 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CB4_RS14180 4c321b06e50edca58d5ca275a554c26a 518 Pfam PF03988 Repeat of Unknown Function (DUF347) 76 126 9.1E-11 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CB4_RS00560 4a3225f6ca89147f2620636e1a462c4e 318 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 26 310 17.525 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CB4_RS00560 4a3225f6ca89147f2620636e1a462c4e 318 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 86 108 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site CB4_RS00560 4a3225f6ca89147f2620636e1a462c4e 318 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 30 307 2.9E-85 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CB4_RS00560 4a3225f6ca89147f2620636e1a462c4e 318 Pfam PF01040 UbiA prenyltransferase family 43 293 7.4E-57 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CB4_RS03140 1ef2d0e9d44a39d1fc35b60e2c2d9419 266 Pfam PF01061 ABC-2 type transporter 17 224 5.0E-25 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CB4_RS15520 141dd31dafe678dbdc85be0996d45e63 175 Pfam PF05119 Phage terminase, small subunit 50 162 1.4E-17 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CB4_RS15520 141dd31dafe678dbdc85be0996d45e63 175 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 40 170 1.6E-24 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CB4_RS09180 fc977e9d418ba57b0e61e5a88897bf6a 258 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 8 252 4.1E-60 T 29-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 CB4_RS09180 fc977e9d418ba57b0e61e5a88897bf6a 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 74 93 3.2E-27 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CB4_RS09180 fc977e9d418ba57b0e61e5a88897bf6a 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 16 37 3.2E-27 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CB4_RS09180 fc977e9d418ba57b0e61e5a88897bf6a 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 199 218 3.2E-27 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CB4_RS09180 fc977e9d418ba57b0e61e5a88897bf6a 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 177 199 3.2E-27 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CB4_RS09180 fc977e9d418ba57b0e61e5a88897bf6a 258 Pfam PF01311 Bacterial export proteins, family 1 8 242 2.5E-67 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CB4_RS03330 391a9220924f176cf0980035bc90e841 487 PIRSF PIRSF016636 1 487 3.9E-144 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CB4_RS03330 391a9220924f176cf0980035bc90e841 487 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 143 375 2.3E-29 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CB4_RS03330 391a9220924f176cf0980035bc90e841 487 PIRSF PIRSF500217 1 487 3.8E-144 T 29-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CB4_RS16745 38ea2c841d63a231ac1e647dccc31c6c 151 Pfam PF00877 NlpC/P60 family 44 149 8.6E-32 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CB4_RS16745 38ea2c841d63a231ac1e647dccc31c6c 151 SUPERFAMILY SSF54001 29 151 1.82E-43 T 29-03-2018 CB4_RS16745 38ea2c841d63a231ac1e647dccc31c6c 151 Gene3D G3DSA:3.90.1720.10 20 151 3.1E-42 T 29-03-2018 CB4_RS11815 27843b27a693b55b9129622046ebee49 264 SUPERFAMILY SSF53335 1 220 1.89E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS11815 27843b27a693b55b9129622046ebee49 264 Gene3D G3DSA:3.40.50.150 1 246 3.5E-10 T 29-03-2018 CB4_RS05105 c1461b94994899d4468f166f4feccd75 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 7.3E-34 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS05105 c1461b94994899d4468f166f4feccd75 292 Gene3D G3DSA:1.10.3470.10 1 277 3.8E-47 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS03525 11aa838f754b23fe9a245a0d51563b1b 279 SUPERFAMILY SSF52518 5 272 3.71E-100 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CB4_RS03525 11aa838f754b23fe9a245a0d51563b1b 279 Gene3D G3DSA:3.40.50.970 2 278 7.8E-87 T 29-03-2018 CB4_RS03525 11aa838f754b23fe9a245a0d51563b1b 279 ProSitePatterns PS00801 Transketolase signature 1. 18 38 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CB4_RS03525 11aa838f754b23fe9a245a0d51563b1b 279 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 14 270 9.4E-70 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CB4_RS18325 6541e5461d1a1834d358c96bdb0e5ed5 495 Pfam PF07261 Replication initiation and membrane attachment 331 406 7.4E-13 T 29-03-2018 IPR006343 DnaD domain CB4_RS18325 6541e5461d1a1834d358c96bdb0e5ed5 495 Gene3D G3DSA:1.10.10.630 327 405 7.8E-13 T 29-03-2018 IPR034829 DnaD-like domain CB4_RS16590 563b56f7bdb0490b1d004611010fb762 71 Pfam PF11148 Protein of unknown function (DUF2922) 2 68 4.4E-20 T 29-03-2018 IPR021321 Protein of unknown function DUF2922 CB4_RS18585 8db6dafbe67205049bcfee52a9848879 402 Gene3D G3DSA:1.25.40.10 264 384 1.3E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS08830 f73a79bf76e077dbb4602aad48f6b0d5 146 SUPERFAMILY SSF103084 1 134 2.35E-25 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CB4_RS08830 f73a79bf76e077dbb4602aad48f6b0d5 146 Pfam PF05866 Endodeoxyribonuclease RusA 8 133 1.9E-34 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CB4_RS08830 f73a79bf76e077dbb4602aad48f6b0d5 146 Gene3D G3DSA:3.30.1330.70 1 139 3.6E-32 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CB4_RS13935 f6938724c06fcc5c923b6b86fe11d00c 30 Gene3D G3DSA:1.10.443.10 1 29 4.1E-6 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS13935 f6938724c06fcc5c923b6b86fe11d00c 30 SUPERFAMILY SSF56349 2 27 1.06E-5 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CB4_RS13935 f6938724c06fcc5c923b6b86fe11d00c 30 Pfam PF00589 Phage integrase family 2 27 2.1E-5 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CB4_RS06045 8e3726ec2d1329b038188ee971e9197f 255 Gene3D G3DSA:3.40.50.720 2 247 6.2E-44 T 29-03-2018 CB4_RS06045 8e3726ec2d1329b038188ee971e9197f 255 SUPERFAMILY SSF69572 4 242 5.76E-60 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CB4_RS06045 8e3726ec2d1329b038188ee971e9197f 255 Pfam PF00899 ThiF family 9 235 1.4E-38 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CB4_RS13780 76fefee912964310ac7170b5533c66c9 121 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 118 16.782 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CB4_RS13780 76fefee912964310ac7170b5533c66c9 121 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 113 7.8E-22 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CB4_RS04975 f4a2216654c39ef017c8f7ca87440703 154 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 3.0E-34 T 29-03-2018 IPR009370 Protein of unknown function DUF1027 CB4_RS04975 f4a2216654c39ef017c8f7ca87440703 154 PIRSF PIRSF012565 1 152 5.9E-46 T 29-03-2018 IPR009370 Protein of unknown function DUF1027 CB4_RS12055 9df67520372b76562bd1b15461b8103e 303 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 240 261 - T 29-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CB4_RS12055 9df67520372b76562bd1b15461b8103e 303 Gene3D G3DSA:3.10.180.10 1 125 3.8E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS12055 9df67520372b76562bd1b15461b8103e 303 Gene3D G3DSA:3.10.180.10 146 301 1.2E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS12055 9df67520372b76562bd1b15461b8103e 303 SUPERFAMILY SSF54593 1 270 6.44E-44 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CB4_RS12055 9df67520372b76562bd1b15461b8103e 303 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 146 262 1.1E-15 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CB4_RS12055 9df67520372b76562bd1b15461b8103e 303 TIGRFAM TIGR03211 catechol_2_3: catechol 2,3 dioxygenase 3 301 4.2E-128 T 29-03-2018 IPR017624 Catechol 2,3 dioxygenase GO:0008198|GO:0018577|GO:0019439|GO:0055114 KEGG: 00361+1.13.11.2|KEGG: 00362+1.13.11.2|KEGG: 00622+1.13.11.2|KEGG: 00643+1.13.11.2|MetaCyc: PWY-5419|MetaCyc: PWY-5641 CB4_RS13640 235e00f568f72bfb9bb488e2ac453624 123 TIGRFAM TIGR03987 TIGR03987: TIGR03987 family protein 2 117 3.2E-48 T 29-03-2018 IPR023813 Conserved hypothetical protein CHP03987 CB4_RS02490 031c0bd932dc407eaac9711261213ffc 320 Pfam PF05816 Toxic anion resistance protein (TelA) 21 285 3.6E-57 T 29-03-2018 IPR008863 Toxic anion resistance CB4_RS09935 8269dceaeaeb9f588943e6bc88e20eaf 270 SUPERFAMILY SSF56529 36 245 6.41E-64 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS09935 8269dceaeaeb9f588943e6bc88e20eaf 270 Gene3D G3DSA:3.90.850.10 6 251 1.1E-65 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS09935 8269dceaeaeb9f588943e6bc88e20eaf 270 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 46 243 9.3E-51 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS20315 50458a2094285cea5f9fe7db4ca49a21 235 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CB4_RS20315 50458a2094285cea5f9fe7db4ca49a21 235 Pfam PF00005 ABC transporter 17 162 3.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CB4_RS20315 50458a2094285cea5f9fe7db4ca49a21 235 SMART SM00382 26 211 6.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CB4_RS20315 50458a2094285cea5f9fe7db4ca49a21 235 PIRSF PIRSF039137 1 235 2.1E-112 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CB4_RS20315 50458a2094285cea5f9fe7db4ca49a21 235 Gene3D G3DSA:3.40.50.300 1 235 3.3E-59 T 29-03-2018 CB4_RS20315 50458a2094285cea5f9fe7db4ca49a21 235 SUPERFAMILY SSF52540 2 232 5.77E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19485 b5913b08d50cbc451a659e798441f5c7 126 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 5 107 5.7E-22 T 29-03-2018 IPR019277 Protein of unknown function DUF2304 CB4_RS03365 ac7f49cbef1a38f6f6cb2c2a457444d7 149 SUPERFAMILY SSF48452 43 103 1.99E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS03365 ac7f49cbef1a38f6f6cb2c2a457444d7 149 Gene3D G3DSA:1.25.40.10 42 119 6.5E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CB4_RS11870 b058d968f39bafd92a2f90dde2c2011f 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 1.6E-40 T 29-03-2018 IPR007347 Sporulation stage V, protein S CB4_RS11870 b058d968f39bafd92a2f90dde2c2011f 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 1.0E-38 T 29-03-2018 IPR007347 Sporulation stage V, protein S CB4_RS09005 740c5e9780ce7b219db6a1097f3fb466 377 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 33 197 4.7E-6 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CB4_RS09005 740c5e9780ce7b219db6a1097f3fb466 377 SUPERFAMILY SSF55073 31 212 5.49E-10 T 29-03-2018 IPR029787 Nucleotide cyclase CB4_RS09005 740c5e9780ce7b219db6a1097f3fb466 377 Gene3D G3DSA:3.30.70.1230 22 217 2.1E-9 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CB4_RS19480 08391da657e282281c460c2a207c0d99 617 Pfam PF13487 HD domain 439 500 7.0E-15 T 29-03-2018 CB4_RS19480 08391da657e282281c460c2a207c0d99 617 Gene3D G3DSA:1.10.3210.10 344 558 3.7E-37 T 29-03-2018 CB4_RS19480 08391da657e282281c460c2a207c0d99 617 SUPERFAMILY SSF109604 377 548 5.65E-23 T 29-03-2018 CB4_RS19480 08391da657e282281c460c2a207c0d99 617 Gene3D G3DSA:3.30.450.40 32 139 0.0019 T 29-03-2018 IPR029016 GAF domain-like CB4_RS10990 3a663c3086cbc7a0425f8d787bc372c5 246 Pfam PF13649 Methyltransferase domain 55 153 3.3E-19 T 29-03-2018 CB4_RS10990 3a663c3086cbc7a0425f8d787bc372c5 246 SUPERFAMILY SSF53335 38 239 2.89E-34 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS10990 3a663c3086cbc7a0425f8d787bc372c5 246 Gene3D G3DSA:3.40.50.150 11 238 2.2E-32 T 29-03-2018 CB4_RS11195 2c83970301f7cae28c3ab854822a04a5 478 Pfam PF01943 Polysaccharide biosynthesis protein 9 270 2.1E-15 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CB4_RS13800 700072d7485fd569511885b7d1544997 311 Gene3D G3DSA:3.90.320.10 61 245 1.4E-10 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CB4_RS13800 700072d7485fd569511885b7d1544997 311 Pfam PF12705 PD-(D/E)XK nuclease superfamily 12 306 2.7E-10 T 29-03-2018 CB4_RS01430 49682445febee2862540f89b8d677c63 107 Pfam PF04977 Septum formation initiator 25 102 3.6E-17 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CB4_RS05355 ee300842eb71020cc5fa4afb0f0a5429 70 Pfam PF14098 Small, acid-soluble spore protein I 6 69 1.1E-26 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 CB4_RS05355 ee300842eb71020cc5fa4afb0f0a5429 70 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 4 70 17.833 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 CB4_RS05355 ee300842eb71020cc5fa4afb0f0a5429 70 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 7 70 1.7E-24 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 CB4_RS08190 cd57eb05883c052f2aa47e25005ee7a6 313 Pfam PF00682 HMGL-like 5 274 7.3E-54 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CB4_RS08190 cd57eb05883c052f2aa47e25005ee7a6 313 Gene3D G3DSA:3.20.20.70 1 297 4.3E-104 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS08190 cd57eb05883c052f2aa47e25005ee7a6 313 SUPERFAMILY SSF51569 1 293 8.97E-73 T 29-03-2018 CB4_RS04285 7d2a36381af3572c6031c5db670823d6 246 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 246 43.907 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CB4_RS04285 7d2a36381af3572c6031c5db670823d6 246 Pfam PF02654 Cobalamin-5-phosphate synthase 7 237 2.2E-56 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CB4_RS04285 7d2a36381af3572c6031c5db670823d6 246 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 4 238 1.5E-41 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CB4_RS02710 736bf01818380be969e03d643eaa4059 165 Pfam PF08741 YwhD family 7 164 5.0E-70 T 29-03-2018 IPR014852 Uncharacterised protein YwhD CB4_RS02920 107c91680cef2280aa1c2638cde8a0c4 383 Gene3D G3DSA:3.40.50.2000 1 226 6.1E-88 T 29-03-2018 CB4_RS02920 107c91680cef2280aa1c2638cde8a0c4 383 Gene3D G3DSA:3.40.50.2000 302 382 0.25 T 29-03-2018 CB4_RS02920 107c91680cef2280aa1c2638cde8a0c4 383 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 363 2.7E-120 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CB4_RS02920 107c91680cef2280aa1c2638cde8a0c4 383 SUPERFAMILY SSF53756 3 372 3.23E-138 T 29-03-2018 CB4_RS02920 107c91680cef2280aa1c2638cde8a0c4 383 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 366 1.2E-163 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CB4_RS05020 996a60c7b3e7631ab794f0354762974b 352 Gene3D G3DSA:3.40.50.2300 160 316 1.1E-24 T 29-03-2018 CB4_RS05020 996a60c7b3e7631ab794f0354762974b 352 Gene3D G3DSA:3.40.50.2300 44 159 4.2E-18 T 29-03-2018 CB4_RS05020 996a60c7b3e7631ab794f0354762974b 352 SUPERFAMILY SSF53822 44 321 9.79E-55 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CB4_RS05020 996a60c7b3e7631ab794f0354762974b 352 Pfam PF13407 Periplasmic binding protein domain 47 303 6.1E-36 T 29-03-2018 IPR025997 Periplasmic binding protein CB4_RS00370 1f9cdaa7dc6f92b6bef5368430349ff2 180 Pfam PF04308 Ribonuclease H-like 17 170 2.0E-51 T 29-03-2018 IPR007405 Bacteriophage KVP40, Orf299 CB4_RS12110 d309027b388b8dd76e99f8e281e7b855 387 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 208 384 3.5E-24 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS12110 d309027b388b8dd76e99f8e281e7b855 387 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 13 386 1.5E-50 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CB4_RS07230 957d641117a9a8ed731382ad9e91d39c 63 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 9 62 1.5E-9 T 29-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 CB4_RS07230 957d641117a9a8ed731382ad9e91d39c 63 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 8 63 1.3E-11 T 29-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 CB4_RS08050 a6e246f12f195d2b3447975d892f836e 126 Pfam PF16258 Domain of unknown function (DUF4912) 22 121 5.4E-15 T 29-03-2018 IPR032585 Protein of unknown function DUF4912 CB4_RS16115 0403e7dd322daddb7e97ea89b298b0ab 104 Pfam PF12986 Domain of unknown function (DUF3870) 8 100 1.2E-25 T 29-03-2018 IPR024617 Domain of unknown function DUF3870 CB4_RS02015 a2ca123036b92babddb90a78bc44d8ec 331 Pfam PF09991 Predicted membrane protein (DUF2232) 16 320 6.7E-47 T 29-03-2018 IPR018710 Protein of unknown function DUF2232 CB4_RS16595 957d5f5b4550d9e966cf2d52a2f29f71 74 Pfam PF07872 Protein of unknown function (DUF1659) 16 51 4.0E-7 T 29-03-2018 IPR012454 Protein of unknown function DUF1659 CB4_RS09585 77ffc285682bd3f31835c7b94fcbf7e0 182 SUPERFAMILY SSF52218 7 177 2.58E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS09585 77ffc285682bd3f31835c7b94fcbf7e0 182 Pfam PF03358 NADPH-dependent FMN reductase 7 149 2.2E-31 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CB4_RS09585 77ffc285682bd3f31835c7b94fcbf7e0 182 Gene3D G3DSA:3.40.50.360 1 181 4.4E-29 T 29-03-2018 IPR029039 Flavoprotein-like domain CB4_RS06320 39b0b398e511e2f8b2792fb493b5467c 415 Pfam PF04286 Protein of unknown function (DUF445) 40 413 1.8E-73 T 29-03-2018 IPR007383 Protein of unknown function DUF445 CB4_RS06320 39b0b398e511e2f8b2792fb493b5467c 415 Gene3D G3DSA:1.25.40.90 261 371 1.4E-4 T 29-03-2018 IPR008942 ENTH/VHS CB4_RS15390 fdb62e61510fca6a0ebe5ba92b875fa2 81 Pfam PF10779 Haemolysin XhlA 6 74 1.4E-8 T 29-03-2018 IPR019715 Haemolysin XhlA CB4_RS14440 7044e09e595beefbbde943ee7adda5ef 662 Pfam PF02687 FtsX-like permease family 117 210 1.3E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CB4_RS14440 7044e09e595beefbbde943ee7adda5ef 662 PIRSF PIRSF018968 33 661 2.3E-117 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CB4_RS08715 4786c6a02aae5371c61ecdb7769c36b5 94 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 84 2.1E-21 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CB4_RS08715 4786c6a02aae5371c61ecdb7769c36b5 94 Gene3D G3DSA:3.40.1690.10 10 87 4.2E-31 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CB4_RS08715 4786c6a02aae5371c61ecdb7769c36b5 94 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 40 61 5.6E-5 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CB4_RS08715 4786c6a02aae5371c61ecdb7769c36b5 94 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 25 5.6E-5 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CB4_RS08715 4786c6a02aae5371c61ecdb7769c36b5 94 SUPERFAMILY SSF160544 8 88 2.75E-26 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CB4_RS06435 33418b341825289e88b271b9b1c298b4 242 Pfam PF04029 2-phosphosulpholactate phosphatase 7 230 3.0E-59 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CB4_RS06435 33418b341825289e88b271b9b1c298b4 242 Gene3D G3DSA:3.90.1560.10 6 239 1.1E-61 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CB4_RS06435 33418b341825289e88b271b9b1c298b4 242 SUPERFAMILY SSF142823 1 232 1.1E-55 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CB4_RS07950 636fba5e70ab1eee9082b0c0bfd90711 74 Pfam PF10031 Small integral membrane protein (DUF2273) 10 54 6.5E-15 T 29-03-2018 IPR018730 Protein of unknown function DUF2273 CB4_RS13695 b88c86837e2059bd5b45c8e235dbe700 130 Pfam PF09946 Predicted membrane protein (DUF2178) 14 118 5.5E-6 T 29-03-2018 IPR019235 Protein of unknown function DUF2178, transmembrane CB4_RS04705 8326fa88c611f4fd526544b44ce8b4cc 395 Pfam PF12791 Anti-sigma factor N-terminus 8 65 1.9E-6 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal CB4_RS17270 1d8718fded47088e43cb162726b8bfa3 235 Pfam PF07730 Histidine kinase 28 90 9.6E-10 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CB4_RS17270 1d8718fded47088e43cb162726b8bfa3 235 Gene3D G3DSA:3.30.565.10 90 232 9.5E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CB4_RS13540 2dd336c7b24aa04d1dee61573200d4d4 411 Pfam PF04932 O-Antigen ligase 199 324 2.9E-10 T 29-03-2018 IPR007016 O-antigen ligase-related CB4_RS11735 b2b63f1ff7dcfd817fabffa5fe96d229 146 Pfam PF10782 Zinc-finger 19 78 1.1E-5 T 29-03-2018 IPR019718 Protein of unknown function DUF2602 CB4_RS12560 deae576814236716543f8c0a42765b4c 157 SUPERFAMILY SSF54690 5 139 4.18E-44 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CB4_RS12560 deae576814236716543f8c0a42765b4c 157 Pfam PF02391 MoaE protein 8 119 7.3E-34 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CB4_RS12560 deae576814236716543f8c0a42765b4c 157 Gene3D G3DSA:3.90.1170.40 2 146 2.7E-45 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CB4_RS10470 07df346718a7c9684ad3e272a04560fd 399 Pfam PF09992 Phosphodiester glycosidase 191 379 2.0E-43 T 29-03-2018 IPR018711 Phosphodiester glycosidase CB4_RS02830 83745d7195b3393f2294bd8104f1bf86 261 Pfam PF02673 Bacitracin resistance protein BacA 6 250 3.5E-73 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CB4_RS02830 83745d7195b3393f2294bd8104f1bf86 261 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 256 16.323 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CB4_RS17420 3893752497e3aeead69386c73202d5e5 234 PRINTS PR01837 MgtC/SapB protein signature 12 31 3.2E-38 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CB4_RS17420 3893752497e3aeead69386c73202d5e5 234 PRINTS PR01837 MgtC/SapB protein signature 31 49 3.2E-38 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CB4_RS17420 3893752497e3aeead69386c73202d5e5 234 PRINTS PR01837 MgtC/SapB protein signature 93 117 3.2E-38 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CB4_RS17420 3893752497e3aeead69386c73202d5e5 234 PRINTS PR01837 MgtC/SapB protein signature 65 87 3.2E-38 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CB4_RS17420 3893752497e3aeead69386c73202d5e5 234 Pfam PF02308 MgtC family 9 137 4.4E-32 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CB4_RS14310 3160057adfcaac38bca22c4c8ad4488d 82 SUPERFAMILY SSF89447 1 53 2.88E-15 T 29-03-2018 CB4_RS14310 3160057adfcaac38bca22c4c8ad4488d 82 Gene3D G3DSA:2.10.260.10 1 48 2.5E-17 T 29-03-2018 CB4_RS14310 3160057adfcaac38bca22c4c8ad4488d 82 SMART SM00966 8 51 2.2E-6 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS14310 3160057adfcaac38bca22c4c8ad4488d 82 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 49 1.9E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CB4_RS13195 02156414b3f64c6f3323dbd3d2a1fed2 95 Gene3D G3DSA:1.10.3990.20 6 70 5.1E-5 T 29-03-2018 CB4_RS10340 6bf19f6e1bb9bd48a2118b7ee212ed20 218 SMART SM00909 110 197 1.6E-5 T 29-03-2018 IPR019606 GerMN domain CB4_RS10340 6bf19f6e1bb9bd48a2118b7ee212ed20 218 Pfam PF10646 Sporulation and spore germination 101 192 3.8E-8 T 29-03-2018 IPR019606 GerMN domain CB4_RS19935 474ef0d1638ce6c00e1e73417fbfd736 75 Pfam PF12645 Helix-turn-helix domain 18 70 6.6E-7 T 29-03-2018 IPR024760 Helix-turn-helix, conjugative transposon-like CB4_RS10220 8cdf757d63e5b9a21a691c8e2735ff5a 112 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 5 103 6.0E-8 T 29-03-2018 IPR010899 Protein of unknown function UPF0344 CB4_RS10220 8cdf757d63e5b9a21a691c8e2735ff5a 112 Pfam PF07457 Protein of unknown function (DUF1516) 2 107 8.2E-25 T 29-03-2018 IPR010899 Protein of unknown function UPF0344 CB4_RS04785 a621e31d87e1c5845e8d269c63e89812 363 TIGRFAM TIGR00277 HDIG: HDIG domain 134 225 1.2E-9 T 29-03-2018 IPR006675 HDIG domain CB4_RS04785 a621e31d87e1c5845e8d269c63e89812 363 Pfam PF01966 HD domain 136 257 4.3E-20 T 29-03-2018 IPR006674 HD domain CB4_RS04785 a621e31d87e1c5845e8d269c63e89812 363 Gene3D G3DSA:1.10.3210.10 29 300 1.2E-46 T 29-03-2018 CB4_RS04785 a621e31d87e1c5845e8d269c63e89812 363 SUPERFAMILY SSF109604 121 295 3.37E-40 T 29-03-2018 CB4_RS04785 a621e31d87e1c5845e8d269c63e89812 363 SMART SM00471 131 267 1.6E-12 T 29-03-2018 IPR003607 HD/PDEase domain CB4_RS00020 e24a340ccd28828db30912b4a13489e1 160 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 33 149 7.8E-39 T 29-03-2018 IPR005562 SpoVA CB4_RS00020 e24a340ccd28828db30912b4a13489e1 160 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 16 151 8.6E-60 T 29-03-2018 IPR014203 Sporulation stage V, protein AC CB4_RS07085 32e1b198e8cc50348bb84525f6a1fcb7 399 Pfam PF06898 Putative stage IV sporulation protein YqfD 6 383 1.6E-114 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CB4_RS07085 32e1b198e8cc50348bb84525f6a1fcb7 399 PIRSF PIRSF029895 1 396 8.8E-118 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CB4_RS07085 32e1b198e8cc50348bb84525f6a1fcb7 399 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 6 384 5.8E-101 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CB4_RS06725 4b14a3c5bd3593264b2337a750b97574 420 SUPERFAMILY SSF118215 7 398 3.53E-119 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS06725 4b14a3c5bd3593264b2337a750b97574 420 PRINTS PR00173 Glutamate-aspartate symporter signature 323 342 3.2E-25 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS06725 4b14a3c5bd3593264b2337a750b97574 420 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 3.2E-25 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS06725 4b14a3c5bd3593264b2337a750b97574 420 PRINTS PR00173 Glutamate-aspartate symporter signature 72 97 3.2E-25 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS06725 4b14a3c5bd3593264b2337a750b97574 420 PRINTS PR00173 Glutamate-aspartate symporter signature 141 163 3.2E-25 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS06725 4b14a3c5bd3593264b2337a750b97574 420 PRINTS PR00173 Glutamate-aspartate symporter signature 288 314 3.2E-25 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS06725 4b14a3c5bd3593264b2337a750b97574 420 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 291 314 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CB4_RS06725 4b14a3c5bd3593264b2337a750b97574 420 Gene3D G3DSA:1.10.3860.10 1 404 7.9E-119 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS06725 4b14a3c5bd3593264b2337a750b97574 420 Pfam PF00375 Sodium:dicarboxylate symporter family 7 396 3.0E-112 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CB4_RS17475 f11ec20294602400324760301bebfcac 137 SUPERFAMILY SSF140663 1 111 1.1E-28 T 29-03-2018 IPR023203 TTHA0068-like domain CB4_RS17475 f11ec20294602400324760301bebfcac 137 Gene3D G3DSA:1.10.3450.10 1 133 3.0E-30 T 29-03-2018 IPR023203 TTHA0068-like domain CB4_RS17475 f11ec20294602400324760301bebfcac 137 Pfam PF03745 Domain of unknown function (DUF309) 7 61 1.7E-21 T 29-03-2018 IPR005500 Protein of unknown function DUF309 CB4_RS10125 2a7354aa3e0eaf785c43bb01d321ee48 270 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 57 254 1.7E-13 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CB4_RS09245 136ced128227fd1fcca72b399ad14601 476 Gene3D G3DSA:2.160.20.70 187 340 5.1E-8 T 29-03-2018 CB4_RS09245 136ced128227fd1fcca72b399ad14601 476 Pfam PF03961 Flagellar Assembly Protein A 22 470 1.1E-117 T 29-03-2018 IPR005646 Flagellar assembly protein A CB4_RS14170 ca6f3d43f0b25c5cd740c144fa380929 128 ProDom PD049095 YRZH 84 121 1.0E-6 T 29-03-2018 CB4_RS14170 ca6f3d43f0b25c5cd740c144fa380929 128 Pfam PF17428 Family of unknown function (DUF5412) 2 110 4.1E-31 T 29-03-2018 IPR035406 Protein of unknown function DUF5412 CB4_RS11150 71315f558313094bcf461bfdb88e9aea 147 Gene3D G3DSA:3.30.700.10 9 145 0.0012 T 29-03-2018 CB4_RS19160 9c82a5f789ba117f194646245ffcc077 115 Pfam PF11337 Protein of unknown function (DUF3139) 7 91 5.6E-12 T 29-03-2018 IPR021486 Protein of unknown function DUF3139 CB4_RS04305 53c35ea9baf1645d9adfd5d4119eeac3 320 Pfam PF03186 CobD/Cbib protein 7 298 4.3E-101 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CB4_RS04305 53c35ea9baf1645d9adfd5d4119eeac3 320 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 319 99.491 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CB4_RS04305 53c35ea9baf1645d9adfd5d4119eeac3 320 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 4 313 5.7E-83 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CB4_RS13810 b203efa6c051d112e0f8e7b1cdb7492d 83 Pfam PF13025 Protein of unknown function (DUF3886) 15 81 8.7E-19 T 29-03-2018 IPR024980 Protein of unknown function DUF3886 CB4_RS13000 1928e4223b2f6085a8b69703cc1b9e2b 211 SUPERFAMILY SSF51230 39 113 4.32E-10 T 29-03-2018 IPR011053 Single hybrid motif CB4_RS13000 1928e4223b2f6085a8b69703cc1b9e2b 211 Gene3D G3DSA:2.40.50.100 39 120 1.3E-14 T 29-03-2018 CB4_RS13000 1928e4223b2f6085a8b69703cc1b9e2b 211 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 25 161 4.2E-20 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CB4_RS03490 4704431fd82ab9a068001fb1848e9f65 476 Gene3D G3DSA:1.20.1330.10 273 447 1.3E-29 T 29-03-2018 CB4_RS03490 4704431fd82ab9a068001fb1848e9f65 476 SUPERFAMILY SSF64518 36 105 3.92E-32 T 29-03-2018 CB4_RS03490 4704431fd82ab9a068001fb1848e9f65 476 SUPERFAMILY SSF64518 351 475 3.92E-32 T 29-03-2018 CB4_RS03490 4704431fd82ab9a068001fb1848e9f65 476 SUPERFAMILY SSF64518 147 245 3.92E-32 T 29-03-2018 CB4_RS03490 4704431fd82ab9a068001fb1848e9f65 476 Pfam PF00700 Bacterial flagellin C-terminal helical region 389 474 6.4E-29 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CB4_RS05845 9fae48cd8a370bc3be42ce5efb48b8b5 281 Pfam PF02163 Peptidase family M50 111 164 8.3E-7 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CB4_RS05845 9fae48cd8a370bc3be42ce5efb48b8b5 281 Pfam PF02163 Peptidase family M50 28 97 1.9E-7 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CB4_RS16615 d6269befd57561970b8d9691c1941d91 332 Pfam PF01384 Phosphate transporter family 22 321 1.2E-89 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CB4_RS15220 e75b9f088265a3549e18be464bb9a043 88 Pfam PF14069 Stage VI sporulation protein F 12 80 7.6E-17 T 29-03-2018 IPR025942 Stage VI sporulation protein F CB4_RS02995 663b2ed1b59bb822625303205c6a1861 122 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 5 122 20.379 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CB4_RS02995 663b2ed1b59bb822625303205c6a1861 122 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 121 1.8E-39 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CB4_RS17090 786fbf966e7226ed88a947d09c740044 72 Pfam PF07561 Domain of Unknown Function (DUF1540) 5 66 1.2E-14 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 CB4_RS19470 e095b75e000e31b982f259a9b13fa35d 94 Pfam PF10719 Late competence development protein ComFB 4 85 1.2E-21 T 29-03-2018 IPR019657 Late competence development protein ComFB CB4_RS14675 5a7e378e42b4ca905e5b452d9796c1f7 485 Pfam PF14395 Phage phiEco32-like COOH.NH2 ligase-type 2 213 467 2.3E-93 T 29-03-2018 IPR025681 Phage phiEco32-like COOH-NH2 ligase-type 2 CB4_RS11025 cf121e1498e2eee8d32c3dbe4270b02f 215 Pfam PF04012 PspA/IM30 family 3 211 8.3E-22 T 29-03-2018 IPR007157 PspA/IM30 CB4_RS10920 5d634ffbfedf254d42cba74b3826bd02 162 Pfam PF00583 Acetyltransferase (GNAT) family 15 139 3.6E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS10920 5d634ffbfedf254d42cba74b3826bd02 162 SUPERFAMILY SSF55729 1 159 6.69E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS10920 5d634ffbfedf254d42cba74b3826bd02 162 Gene3D G3DSA:3.40.630.30 1 161 3.3E-23 T 29-03-2018 CB4_RS05925 deb40d4f9e91f3a30fbb74e7fcf67f71 197 Pfam PF08977 Bypass of Forespore C, N terminal 54 103 8.2E-12 T 29-03-2018 IPR015071 Bypass-of-forespore C, N-terminal CB4_RS05925 deb40d4f9e91f3a30fbb74e7fcf67f71 197 Pfam PF08955 BofC C-terminal domain 108 183 4.7E-23 T 29-03-2018 IPR015050 Bypass of forespore C, C-terminal CB4_RS08435 ab2184b047400b8a55c9a13316d3da65 574 Gene3D G3DSA:1.10.8.50 168 237 4.2E-25 T 29-03-2018 CB4_RS08435 ab2184b047400b8a55c9a13316d3da65 574 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 444 3.1E-152 T 29-03-2018 CB4_RS08435 ab2184b047400b8a55c9a13316d3da65 574 Pfam PF05670 Domain of unknown function (DUF814) 453 537 1.3E-27 T 29-03-2018 IPR008532 Domain of unknown function DUF814 CB4_RS08435 ab2184b047400b8a55c9a13316d3da65 574 Gene3D G3DSA:3.40.970.40 241 289 6.7E-15 T 29-03-2018 CB4_RS08435 ab2184b047400b8a55c9a13316d3da65 574 Gene3D G3DSA:2.30.310.10 1 167 2.5E-47 T 29-03-2018 CB4_RS04055 09da12eb3354309168e32389044cba34 116 SMART SM00493 7 81 9.3E-7 T 29-03-2018 IPR006171 TOPRIM domain CB4_RS04055 09da12eb3354309168e32389044cba34 116 Gene3D G3DSA:3.40.1360.20 5 115 3.7E-18 T 29-03-2018 CB4_RS04055 09da12eb3354309168e32389044cba34 116 SUPERFAMILY SSF110455 4 111 3.92E-30 T 29-03-2018 CB4_RS15340 b6b0730fdf0ac354dd5b5e67d1c16594 202 Pfam PF02517 CAAX protease self-immunity 101 181 3.1E-10 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CB4_RS15870 fc61b24d37936b4c4dc2a80c4dc6ff1a 276 Pfam PF01940 Integral membrane protein DUF92 12 257 2.2E-61 T 29-03-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 CB4_RS12600 d487e8e9bc61e5c3858640b9f6a43a59 94 Pfam PF12823 Domain of unknown function (DUF3817) 8 93 4.6E-24 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CB4_RS12600 d487e8e9bc61e5c3858640b9f6a43a59 94 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 10 93 1.4E-29 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CB4_RS08175 baf93e4424ebd95fe5decb3e5c62771f 220 Gene3D G3DSA:1.20.5.170 70 158 0.0014 T 29-03-2018 CB4_RS08175 baf93e4424ebd95fe5decb3e5c62771f 220 Gene3D G3DSA:1.20.5.370 159 187 7.6E-4 T 29-03-2018 CB4_RS08175 baf93e4424ebd95fe5decb3e5c62771f 220 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 4 82 3.4E-42 T 29-03-2018 IPR014243 Transcription factor, RsfA CB4_RS08175 baf93e4424ebd95fe5decb3e5c62771f 220 Gene3D G3DSA:1.10.10.60 4 69 9.9E-5 T 29-03-2018 CB4_RS03470 8566242698da2a0c8fb1fe6fd10853a1 1345 Gene3D G3DSA:1.20.1270.10 886 967 0.088 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CB4_RS12180 0798e753f4629574420ba2f0a9826846 242 Gene3D G3DSA:1.20.5.140 175 189 9.6E-5 T 29-03-2018 CB4_RS12180 0798e753f4629574420ba2f0a9826846 242 Pfam PF00929 Exonuclease 14 182 3.3E-19 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS12180 0798e753f4629574420ba2f0a9826846 242 SUPERFAMILY SSF53098 11 212 2.95E-27 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS12180 0798e753f4629574420ba2f0a9826846 242 Gene3D G3DSA:3.30.420.10 10 174 1.5E-26 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CB4_RS12180 0798e753f4629574420ba2f0a9826846 242 SMART SM00479 11 191 2.1E-23 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CB4_RS15695 8954c0218909593ad044384504485437 98 Pfam PF03050 Transposase IS66 family 18 61 3.6E-11 T 29-03-2018 IPR004291 Transposase, IS66 CB4_RS06960 1bfd2ccf7e16cdcc9ef392b3491aedab 183 Pfam PF02698 DUF218 domain 36 173 4.9E-32 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CB4_RS06960 1bfd2ccf7e16cdcc9ef392b3491aedab 183 Gene3D G3DSA:3.40.50.620 24 161 6.8E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CB4_RS16515 b107f0e9d17239bcc83dc2b788db7723 376 Gene3D G3DSA:3.90.1720.10 191 376 5.6E-19 T 29-03-2018 CB4_RS16515 b107f0e9d17239bcc83dc2b788db7723 376 Pfam PF12671 Putative amidase domain 199 370 8.7E-43 T 29-03-2018 IPR024301 Putative amidase domain CB4_RS16275 5853661af21558607d345bf01e4120a3 90 Pfam PF13129 Protein of unknown function (DUF3953) 41 80 3.0E-5 T 29-03-2018 IPR025018 Protein of unknown function DUF3953 CB4_RS14330 4e50eb83c46576964cf9ffd3ea618c2b 235 Pfam PF02517 CAAX protease self-immunity 145 229 3.8E-19 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CB4_RS19475 f93d453da797b15adeefc25fe55179d6 266 Gene3D G3DSA:3.20.20.70 10 265 6.0E-34 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CB4_RS19475 f93d453da797b15adeefc25fe55179d6 266 SUPERFAMILY SSF51445 27 237 1.01E-12 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CB4_RS19475 f93d453da797b15adeefc25fe55179d6 266 Pfam PF03537 Glycoside-hydrolase family GH114 41 236 2.4E-10 T 29-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain CB4_RS02075 ca0206ad65b0f33363b90db3c4714ab1 71 TIGRFAM TIGR04129 CxxH_BA5709: CxxH/CxxC protein, BA_5709 family 19 70 1.1E-15 T 29-03-2018 IPR025626 YyzF-like protein CB4_RS02075 ca0206ad65b0f33363b90db3c4714ab1 71 Pfam PF14116 YyzF-like protein 20 70 2.5E-15 T 29-03-2018 IPR025626 YyzF-like protein CB4_RS05690 5540999fcb78132fee25d5c1221d86a2 347 SUPERFAMILY SSF56059 198 339 2.9E-17 T 29-03-2018 CB4_RS05690 5540999fcb78132fee25d5c1221d86a2 347 SUPERFAMILY SSF56059 110 168 2.9E-17 T 29-03-2018 CB4_RS00265 185a9c1d4c0287f80e51e955ee3203de 268 Gene3D G3DSA:1.20.1080.10 2 264 4.4E-85 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CB4_RS00265 185a9c1d4c0287f80e51e955ee3203de 268 Pfam PF01226 Formate/nitrite transporter 8 250 3.5E-76 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CB4_RS18575 c9383580688c4c1454e7c561e40fd541 226 Pfam PF12229 Putative peptidoglycan binding domain 86 190 5.1E-8 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain CB4_RS08590 245b9f1e4b27ac2c721e72afc3421eed 177 Pfam PF02620 Uncharacterized ACR, COG1399 59 171 4.7E-29 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CB4_RS12095 3fdf244b92a5bf45cd354285d4bc882e 263 Gene3D G3DSA:3.90.850.10 2 263 2.7E-44 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS12095 3fdf244b92a5bf45cd354285d4bc882e 263 SUPERFAMILY SSF56529 3 260 5.1E-76 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS12095 3fdf244b92a5bf45cd354285d4bc882e 263 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 104 258 1.4E-6 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CB4_RS11930 d33802fe83b0767bc94266bc285ca2b0 108 Pfam PF08858 IDEAL domain 73 104 9.0E-8 T 29-03-2018 IPR014957 IDEAL domain CB4_RS11930 d33802fe83b0767bc94266bc285ca2b0 108 SMART SM00914 70 107 3.3E-4 T 29-03-2018 IPR014957 IDEAL domain CB4_RS08930 e803791eee1b2e8f8ad301828d40143a 142 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 11 93 8.9E-7 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CB4_RS08930 e803791eee1b2e8f8ad301828d40143a 142 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 7 134 6.9E-22 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CB4_RS14185 4a1757827ef9a99962f0f0b184fde042 102 Pfam PF09685 Domain of unknown function (DUF4870) 7 99 1.2E-15 T 29-03-2018 IPR019109 Protein of unknown function DUF4870 CB4_RS11185 c7c66e4981836fb9e6321d8ed93738ba 204 Pfam PF02397 Bacterial sugar transferase 2 176 1.7E-65 T 29-03-2018 IPR003362 Bacterial sugar transferase CB4_RS10245 c46551ecfb6c6a3d3b78d415c74e39f5 198 Pfam PF09335 SNARE associated Golgi protein 29 154 3.6E-23 T 29-03-2018 IPR032816 SNARE associated Golgi protein CB4_RS08345 e7324e532e292271122e6ae8d55080ed 89 Pfam PF02325 YGGT family 10 76 5.7E-21 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 CB4_RS15815 11799bc17f1172519831f0bb17bdb69e 194 Pfam PF01596 O-methyltransferase 28 157 1.9E-27 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CB4_RS15815 11799bc17f1172519831f0bb17bdb69e 194 Gene3D G3DSA:3.40.50.150 18 187 1.4E-29 T 29-03-2018 CB4_RS15815 11799bc17f1172519831f0bb17bdb69e 194 SUPERFAMILY SSF53335 25 194 2.97E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS07120 de82cf826603cb68fbad84f920229485 50 Pfam PF14006 YqzL-like protein 4 24 4.5E-8 T 29-03-2018 IPR025617 YqzL-like protein CB4_RS08200 30495115a227553302b900b9c3a4da66 202 SUPERFAMILY SSF46689 17 88 8.48E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CB4_RS08200 30495115a227553302b900b9c3a4da66 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 5.3E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS08200 30495115a227553302b900b9c3a4da66 202 Gene3D G3DSA:1.10.10.60 58 150 3.2E-10 T 29-03-2018 CB4_RS08200 30495115a227553302b900b9c3a4da66 202 Gene3D G3DSA:1.10.10.60 7 57 6.7E-15 T 29-03-2018 CB4_RS08200 30495115a227553302b900b9c3a4da66 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS08200 30495115a227553302b900b9c3a4da66 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CB4_RS05580 332476610f6a295aaaad5e7b0dc94024 351 SMART SM00909 246 332 9.9E-8 T 29-03-2018 IPR019606 GerMN domain CB4_RS05580 332476610f6a295aaaad5e7b0dc94024 351 SMART SM00909 96 186 1.3E-20 T 29-03-2018 IPR019606 GerMN domain CB4_RS05580 332476610f6a295aaaad5e7b0dc94024 351 Pfam PF10646 Sporulation and spore germination 70 183 4.1E-21 T 29-03-2018 IPR019606 GerMN domain CB4_RS05580 332476610f6a295aaaad5e7b0dc94024 351 Pfam PF10646 Sporulation and spore germination 218 327 4.4E-12 T 29-03-2018 IPR019606 GerMN domain CB4_RS03050 e4e18f1d670ac9e4fdf8f34482963ad9 74 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 7 70 7.0E-14 T 29-03-2018 IPR009526 Protein of unknown function DUF1146 CB4_RS03050 e4e18f1d670ac9e4fdf8f34482963ad9 74 Pfam PF06612 Protein of unknown function (DUF1146) 13 59 1.9E-17 T 29-03-2018 IPR009526 Protein of unknown function DUF1146 CB4_RS19635 87b93ca9cfa359190416bd4bd8bc50fe 1212 Gene3D G3DSA:3.40.50.300 39 328 1.7E-6 T 29-03-2018 CB4_RS19635 87b93ca9cfa359190416bd4bd8bc50fe 1212 SUPERFAMILY SSF52540 256 335 9.6E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS19635 87b93ca9cfa359190416bd4bd8bc50fe 1212 SUPERFAMILY SSF52540 57 192 9.6E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CB4_RS09795 816247f54bea23ed06e5c53dfb81d691 221 Pfam PF04012 PspA/IM30 family 2 219 8.5E-50 T 29-03-2018 IPR007157 PspA/IM30 CB4_RS16860 1263c0b48b222a172cc353ea104a4646 164 SUPERFAMILY SSF55729 1 132 4.65E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CB4_RS16860 1263c0b48b222a172cc353ea104a4646 164 Pfam PF00583 Acetyltransferase (GNAT) family 52 121 1.9E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CB4_RS16860 1263c0b48b222a172cc353ea104a4646 164 Gene3D G3DSA:3.40.630.30 1 149 5.3E-17 T 29-03-2018 CB4_RS15645 d76ebe68e978e9b86cb0252144c8f990 517 SUPERFAMILY SSF55383 426 509 2.68E-25 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS15645 d76ebe68e978e9b86cb0252144c8f990 517 Gene3D G3DSA:3.30.457.10 494 515 4.0E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS15645 d76ebe68e978e9b86cb0252144c8f990 517 Gene3D G3DSA:3.30.457.10 319 434 4.8E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS15645 d76ebe68e978e9b86cb0252144c8f990 517 Gene3D G3DSA:3.30.457.10 435 493 2.3E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS15645 d76ebe68e978e9b86cb0252144c8f990 517 Pfam PF07833 Copper amine oxidase N-terminal domain 423 512 6.5E-29 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CB4_RS10475 0b7f94ac8304a3259b991c344c2262db 58 Pfam PF14070 Putative motility protein 3 56 8.5E-22 T 29-03-2018 IPR025906 Putative motility protein CB4_RS14530 334a3671f8f0129e0fadb57e0708b05b 90 ProDom PD058323 YUZF BH2251 5 68 1.0E-11 T 29-03-2018 IPR020139 Protein of unknown function DUF2642 CB4_RS14530 334a3671f8f0129e0fadb57e0708b05b 90 Pfam PF10842 Protein of unknown function (DUF2642) 6 68 2.1E-25 T 29-03-2018 IPR020139 Protein of unknown function DUF2642 CB4_RS07760 5f69519557818bcbd7889b8e4d8998bb 257 SUPERFAMILY SSF53474 2 252 4.77E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS07760 5f69519557818bcbd7889b8e4d8998bb 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 1.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS07760 5f69519557818bcbd7889b8e4d8998bb 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 200 214 1.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS07760 5f69519557818bcbd7889b8e4d8998bb 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 1.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS07760 5f69519557818bcbd7889b8e4d8998bb 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 1.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CB4_RS07760 5f69519557818bcbd7889b8e4d8998bb 257 Pfam PF12146 Serine aminopeptidase, S33 44 236 3.5E-17 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CB4_RS07760 5f69519557818bcbd7889b8e4d8998bb 257 Gene3D G3DSA:3.40.50.1820 2 257 2.4E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CB4_RS20425 25fa66180980aedcab774129054e3c5b 458 Pfam PF00860 Permease family 16 412 1.9E-43 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CB4_RS20425 25fa66180980aedcab774129054e3c5b 458 PIRSF PIRSF005353 1 456 2.8E-158 T 29-03-2018 IPR026033 Purine permease PbuG-like CB4_RS19455 b1e7b61e23c7b4042f8d37d4817b6f27 121 Pfam PF00072 Response regulator receiver domain 4 115 3.1E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS19455 b1e7b61e23c7b4042f8d37d4817b6f27 121 SMART SM00448 2 114 8.5E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CB4_RS19455 b1e7b61e23c7b4042f8d37d4817b6f27 121 SUPERFAMILY SSF52172 1 119 8.11E-39 T 29-03-2018 IPR011006 CheY-like superfamily CB4_RS19455 b1e7b61e23c7b4042f8d37d4817b6f27 121 Gene3D G3DSA:3.40.50.2300 1 121 7.0E-39 T 29-03-2018 CB4_RS19285 24049e3c495f675fa9718c51c0d63f3e 232 Pfam PF13027 Protein of unknown function (DUF3888) 139 200 1.3E-5 T 29-03-2018 IPR024984 Protein of unknown function DUF3888 CB4_RS16550 db35526dcf0bd28a0175c01133aa10de 281 Pfam PF07285 Protein of unknown function (DUF1444) 48 273 2.9E-63 T 29-03-2018 IPR010838 Protein of unknown unction DUF1444 CB4_RS02720 eff4d462d45757253f71fdd3982bfdea 107 Pfam PF05154 TM2 domain 25 81 3.0E-14 T 29-03-2018 IPR007829 TM2 domain CB4_RS11000 cb86abc7bf46d57f6911d4310b2c7ab1 128 Pfam PF03788 LrgA family 19 107 1.5E-25 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CB4_RS05060 de89c82346bc1393c9609b7e3f4b5ec8 261 SUPERFAMILY SSF51735 4 248 2.23E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS05060 de89c82346bc1393c9609b7e3f4b5ec8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.7E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS05060 de89c82346bc1393c9609b7e3f4b5ec8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.7E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS05060 de89c82346bc1393c9609b7e3f4b5ec8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.7E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS05060 de89c82346bc1393c9609b7e3f4b5ec8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.7E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS05060 de89c82346bc1393c9609b7e3f4b5ec8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.7E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS05060 de89c82346bc1393c9609b7e3f4b5ec8 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.7E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CB4_RS05060 de89c82346bc1393c9609b7e3f4b5ec8 261 Gene3D G3DSA:3.40.50.720 2 259 1.5E-51 T 29-03-2018 CB4_RS05060 de89c82346bc1393c9609b7e3f4b5ec8 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 248 3.7E-47 T 29-03-2018 CB4_RS15275 3a0bfed491a03b7ad453d10d3b236193 449 Pfam PF14620 YpeB sporulation 17 378 2.0E-124 T 29-03-2018 IPR014239 Spore germination YpeB GO:0009847 CB4_RS15275 3a0bfed491a03b7ad453d10d3b236193 449 Gene3D G3DSA:3.10.450.40 382 442 5.4E-5 T 29-03-2018 CB4_RS15275 3a0bfed491a03b7ad453d10d3b236193 449 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 12 444 1.2E-137 T 29-03-2018 IPR014239 Spore germination YpeB GO:0009847 CB4_RS15275 3a0bfed491a03b7ad453d10d3b236193 449 Pfam PF03413 Peptidase propeptide and YPEB domain 381 441 5.7E-6 T 29-03-2018 IPR025711 PepSY domain CB4_RS02280 5c88627a999fe9f75404b604e3c903a2 178 Pfam PF04238 Protein of unknown function (DUF420) 45 173 1.5E-46 T 29-03-2018 IPR007352 Protein of unknown function DUF420 CB4_RS02280 5c88627a999fe9f75404b604e3c903a2 178 Gene3D G3DSA:1.20.120.80 13 176 2.3E-12 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CB4_RS08125 132b5d5f4cca6a0abf9593d11343c544 151 SUPERFAMILY SSF50475 8 94 5.05E-13 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS08125 132b5d5f4cca6a0abf9593d11343c544 151 Gene3D G3DSA:2.30.110.10 1 150 1.4E-27 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CB4_RS08125 132b5d5f4cca6a0abf9593d11343c544 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 94 1.9E-9 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CB4_RS10145 3e9a3f27c97a3f900ce80301ab5fe52b 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 249 5.0E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS10145 3e9a3f27c97a3f900ce80301ab5fe52b 290 Gene3D G3DSA:1.10.3720.10 5 258 1.5E-34 T 29-03-2018 CB4_RS10145 3e9a3f27c97a3f900ce80301ab5fe52b 290 SUPERFAMILY SSF161098 9 258 5.23E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS08675 37d61a8e9c13b995843d2bca02f97d3f 142 Pfam PF11068 YlqD protein 4 135 2.9E-31 T 29-03-2018 IPR021297 YlqD protein CB4_RS08105 5c94f2a9212652d8d53b8e7080adc1bd 163 Pfam PF14584 Protein of unknown function (DUF4446) 11 157 6.6E-46 T 29-03-2018 IPR027981 Protein of unknown function DUF4446 CB4_RS16330 7764c81461c2950fb3f583ac897be4e0 384 Pfam PF12982 Protein of unknown function (DUF3866) 32 352 9.6E-105 T 29-03-2018 IPR024479 Protein of unknown function DUF3866 CB4_RS16585 d3dbe75aed5f21b2d93ea7ccdaf8a97c 48 Pfam PF12841 YvrJ protein family 8 41 1.0E-15 T 29-03-2018 IPR024419 Protein of unknown function YvrJ CB4_RS02055 9cef7e2145fcb2c4536c4fd268145d7e 454 Pfam PF07435 YycH protein 5 434 2.6E-40 T 29-03-2018 IPR009996 Regulatory protein YycH CB4_RS18205 33100cb502aafaa4af280588c91a2152 277 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 47 275 4.9E-65 T 29-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CB4_RS18205 33100cb502aafaa4af280588c91a2152 277 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 7 277 39.906 T 29-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CB4_RS18205 33100cb502aafaa4af280588c91a2152 277 Pfam PF02666 Phosphatidylserine decarboxylase 59 274 6.4E-64 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CB4_RS14840 401cf22a92054dedaa3ed7e5ddc1df72 84 PIRSF PIRSF004764 1 84 4.3E-32 T 29-03-2018 IPR024702 Uncharacterised conserved protein YmfJ CB4_RS14840 401cf22a92054dedaa3ed7e5ddc1df72 84 Pfam PF11588 Protein of unknown function (DUF3243) 3 80 5.1E-32 T 29-03-2018 IPR021637 Protein of unknown function DUF3243 CB4_RS08275 6f9b62e8e967243c050f0ab8b1a4618a 256 Pfam PF05949 Bacterial protein of unknown function (DUF881) 98 238 2.7E-43 T 29-03-2018 IPR010273 Protein of unknown function DUF881 CB4_RS13700 8b9af10ab1db9761c69b280e23e48237 216 SMART SM00731 58 200 2.4E-4 T 29-03-2018 IPR006640 SprT-like CB4_RS19810 9d1abf8919ec4e83ebabacd53dfd571d 263 Gene3D G3DSA:3.30.2010.10 58 153 4.5E-17 T 29-03-2018 CB4_RS19810 9d1abf8919ec4e83ebabacd53dfd571d 263 Pfam PF01435 Peptidase family M48 159 243 1.5E-5 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CB4_RS19810 9d1abf8919ec4e83ebabacd53dfd571d 263 Pfam PF01435 Peptidase family M48 66 152 2.6E-16 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CB4_RS06095 4ca4e22c1dba188a25ed10d2df70177e 361 Pfam PF01594 AI-2E family transporter 34 347 1.2E-68 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CB4_RS13065 79c933aadbfc5503d29a3c09e802053f 296 Pfam PF07751 Abi-like protein 42 221 5.8E-51 T 29-03-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like CB4_RS13065 79c933aadbfc5503d29a3c09e802053f 296 PIRSF PIRSF034934 11 296 1.1E-68 T 29-03-2018 IPR017034 Abortive infection system protein AbiD/AbiF CB4_RS18010 6fb90a8c86213edebd9ba90d4d2a275b 208 SUPERFAMILY SSF55469 1 205 4.45E-50 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS18010 6fb90a8c86213edebd9ba90d4d2a275b 208 Gene3D G3DSA:3.40.109.10 1 206 3.0E-43 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CB4_RS18010 6fb90a8c86213edebd9ba90d4d2a275b 208 Pfam PF00881 Nitroreductase family 9 184 7.6E-25 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CB4_RS19915 e543fa4dd21006ba2b3d61d1a18bdf54 126 Gene3D G3DSA:1.10.287.80 4 89 4.4E-5 T 29-03-2018 CB4_RS03300 fd66a54b95784a9a22bedf7a9f66132d 304 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 41 163 2.4E-29 T 29-03-2018 IPR030910 SLAP domain, Bacillus-type CB4_RS03300 fd66a54b95784a9a22bedf7a9f66132d 304 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 189 303 7.2E-17 T 29-03-2018 IPR030910 SLAP domain, Bacillus-type CB4_RS08810 09cdc4a8c58d2041cdd38348d252cc2e 277 Pfam PF06378 Protein of unknown function (DUF1071) 8 139 3.3E-54 T 29-03-2018 IPR009425 Single-strand annealing protein SAK3 CB4_RS14020 68edd0f5a795f8fccf33a9586f960cd0 164 Pfam PF04306 Protein of unknown function (DUF456) 23 162 3.3E-30 T 29-03-2018 IPR007403 Protein of unknown function DUF456 CB4_RS06825 6fdb20537248bd30b62b8506fb99d3a2 134 Pfam PF14107 Domain of unknown function (DUF4280) 16 134 1.0E-30 T 29-03-2018 IPR025460 Protein of unknown function DUF4280 CB4_RS02945 9cbe46fa2d4944bb934fc9975e5467be 126 Pfam PF03899 ATP synthase I chain 12 105 3.1E-9 T 29-03-2018 IPR005598 ATP synthase protein I CB4_RS05185 6178405e66115302b32d120f6cf7219c 87 Pfam PF07293 Protein of unknown function (DUF1450) 1 73 4.5E-30 T 29-03-2018 IPR009910 Protein of unknown function DUF1450 CB4_RS05185 6178405e66115302b32d120f6cf7219c 87 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 1 72 4.0E-16 T 29-03-2018 CB4_RS19895 09df537b75d6dbd4cdb0f8a0900bec95 116 Pfam PF01638 HxlR-like helix-turn-helix 15 100 9.7E-34 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CB4_RS19895 09df537b75d6dbd4cdb0f8a0900bec95 116 SUPERFAMILY SSF46785 3 99 7.21E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS19895 09df537b75d6dbd4cdb0f8a0900bec95 116 Gene3D G3DSA:1.10.10.10 12 110 7.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CB4_RS04375 b135ab29f245951f3a0be8760e0fd0dc 112 Pfam PF07875 Coat F domain 22 83 5.3E-19 T 29-03-2018 IPR012851 Spore coat protein CotF-like CB4_RS04375 b135ab29f245951f3a0be8760e0fd0dc 112 Gene3D G3DSA:1.20.1260.10 1 80 1.0E-5 T 29-03-2018 IPR012347 Ferritin-related CB4_RS05405 996be7dd682631326f99838b2c175196 133 Pfam PF03994 Domain of Unknown Function (DUF350) 78 132 1.8E-13 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CB4_RS05405 996be7dd682631326f99838b2c175196 133 Pfam PF03994 Domain of Unknown Function (DUF350) 13 66 9.8E-13 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CB4_RS10970 24bd1ff1c623e9897fa459be9a028e4e 170 Pfam PF11066 Protein of unknown function (DUF2867) 22 162 1.4E-33 T 29-03-2018 IPR021295 Protein of unknown function DUF2867 CB4_RS17185 45119037eab25668cfbf118ad2390812 268 Pfam PF02596 Uncharacterised ArCR, COG2043 20 229 3.3E-43 T 29-03-2018 IPR003748 Protein of unknown function DUF169 CB4_RS04985 0dfb55ca8e35ab32553b9d21faf92f08 91 Pfam PF11256 Protein of unknown function (DUF3055) 10 88 1.1E-32 T 29-03-2018 IPR021415 Protein of unknown function DUF3055 CB4_RS04430 d4af740a92961d879363b2459e05e739 263 Pfam PF10977 Protein of unknown function (DUF2797) 36 259 7.7E-87 T 29-03-2018 IPR021246 Protein of unknown function DUF2797 CB4_RS02160 0381e337cbfbdabfed0c7c585d6e2ed6 188 Pfam PF14172 Domain of unknown function (DUF4309) 51 168 1.9E-17 T 29-03-2018 IPR025453 Protein of unknown function DUF4309 CB4_RS14720 1c4aab59293b9790a1428b8cf7b9afa4 145 SUPERFAMILY SSF158622 8 128 3.27E-33 T 29-03-2018 IPR023378 YheA/YmcA-like domain CB4_RS14720 1c4aab59293b9790a1428b8cf7b9afa4 145 Gene3D G3DSA:1.20.1500.10 13 121 9.5E-30 T 29-03-2018 IPR023378 YheA/YmcA-like domain CB4_RS14720 1c4aab59293b9790a1428b8cf7b9afa4 145 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 15 119 4.3E-23 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CB4_RS14720 1c4aab59293b9790a1428b8cf7b9afa4 145 PIRSF PIRSF021287 6 128 1.6E-35 T 29-03-2018 IPR016783 Biofilm formation YmcA CB4_RS17935 375ade07981d3ef6e21f184ad0e2952f 413 Gene3D G3DSA:3.40.50.10540 17 413 3.8E-163 T 29-03-2018 IPR023606 CoA-transferase family III domain CB4_RS17935 375ade07981d3ef6e21f184ad0e2952f 413 Pfam PF02515 CoA-transferase family III 23 390 1.5E-140 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CB4_RS17935 375ade07981d3ef6e21f184ad0e2952f 413 SUPERFAMILY SSF89796 22 413 2.22E-149 T 29-03-2018 IPR023606 CoA-transferase family III domain CB4_RS11955 c7b3eef0a18c90bc9d36e14d667a3b48 68 Pfam PF10750 Protein of unknown function (DUF2536) 1 68 2.5E-34 T 29-03-2018 IPR019686 Protein of unknown function DUF2536 CB4_RS14545 a0e2cd22c2eea0a02286f241d60c5504 87 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 6 76 2.7E-26 T 29-03-2018 IPR018680 Protein of unknown function DUF2164 CB4_RS07010 7f530f91a74dac3582cb992b8fbac532 127 SUPERFAMILY SSF51735 5 92 3.29E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain CB4_RS07010 7f530f91a74dac3582cb992b8fbac532 127 Gene3D G3DSA:3.40.50.720 1 106 2.9E-13 T 29-03-2018 CB4_RS08925 3ed3f1b08c8616d3435e6b10117e81ba 120 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 7 103 3.9E-21 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CB4_RS08925 3ed3f1b08c8616d3435e6b10117e81ba 120 Pfam PF05521 Phage head-tail joining protein 7 101 3.7E-31 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CB4_RS13770 d23b2d2621270f2dd31a1bfbeb974398 162 SUPERFAMILY SSF81296 24 116 1.26E-9 T 29-03-2018 IPR014756 Immunoglobulin E-set CB4_RS13770 d23b2d2621270f2dd31a1bfbeb974398 162 Pfam PF04234 CopC domain 25 115 3.7E-10 T 29-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CB4_RS13770 d23b2d2621270f2dd31a1bfbeb974398 162 Gene3D G3DSA:2.60.40.1220 22 116 6.4E-15 T 29-03-2018 CB4_RS18615 e8895206b7d923a5f01bd7b41d5af8e8 418 Pfam PF04773 FecR protein 67 164 1.2E-11 T 29-03-2018 IPR006860 FecR protein CB4_RS20705 d60d38cc200abbc6ce2c3c0ee9dd23c6 240 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 11 220 1.0E-53 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CB4_RS09515 3bdff6ad78fa246c830f2ac96eab9fe1 254 Gene3D G3DSA:2.60.40.1120 102 250 6.6E-4 T 29-03-2018 CB4_RS07070 d715c48a808de511c39cef4aca2f3285 338 Pfam PF09992 Phosphodiester glycosidase 157 333 6.2E-36 T 29-03-2018 IPR018711 Phosphodiester glycosidase CB4_RS07685 a65716b24b51d5a9719d4a3b3af92e15 138 Gene3D G3DSA:2.20.28.10 2 38 0.045 T 29-03-2018 CB4_RS05030 c0e8dd818196b91b94852c187f2de504 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 316 3.0E-44 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS05030 c0e8dd818196b91b94852c187f2de504 328 Gene3D G3DSA:1.10.3470.10 31 328 3.2E-34 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS15680 d541aab42497bdc7440fdbd8c2170400 178 Pfam PF06114 IrrE N-terminal-like domain 48 148 6.8E-9 T 29-03-2018 IPR010359 IrrE N-terminal-like domain CB4_RS00270 e85a69435c40f1daeb3152795dee5a0c 157 Pfam PF07849 Protein of unknown function (DUF1641) 118 154 8.6E-12 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 CB4_RS07440 6ca13af153bea05be1f68cbf8b748dfd 167 Pfam PF13047 Protein of unknown function (DUF3907) 10 159 6.7E-55 T 29-03-2018 IPR025013 Protein of unknown function DUF3907 CB4_RS05335 bcd1a0fbc5f2ae56b218d2a342392d59 124 Pfam PF10710 Protein of unknown function (DUF2512) 9 119 7.5E-10 T 29-03-2018 IPR019649 Protein of unknown function DUF2512 CB4_RS13415 eaf968db3a15ba0a59f8a81edef53c5d 262 Gene3D G3DSA:2.70.240.10 53 224 4.0E-4 T 29-03-2018 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CB4_RS15610 cf5d222bf3f7fa55f7a06546df1fdee6 86 Gene3D G3DSA:1.10.10.60 1 39 1.5E-6 T 29-03-2018 CB4_RS08070 0b60f0e5c050953443f7ae28c2a5d904 97 Pfam PF11256 Protein of unknown function (DUF3055) 5 84 8.9E-30 T 29-03-2018 IPR021415 Protein of unknown function DUF3055 CB4_RS07650 9d204891c3f369bdfdc0c10667e25dd8 113 Pfam PF15980 Putative Competence protein ComGF 11 95 9.8E-7 T 29-03-2018 IPR016977 Competence operon G, ComGF CB4_RS08985 88fcafbb2eaf65bbbd838e0323d14ddd 60 ProDom PD019268 UVIB BACTERIOCIN BHLA PLASMID ANTIBIOTIC HOLIN-LIKE PRECURSOR ANTIMICROBIAL SIGNAL PROPHAGE-DERIVED 1 58 0.004 T 29-03-2018 IPR024405 Prophage protein BhlA/UviB CB4_RS19540 9f68ad0facd2f14b89a752a3491941f8 181 Pfam PF07799 Protein of unknown function (DUF1643) 24 157 2.4E-23 T 29-03-2018 IPR012441 Protein of unknown function DUF1643 CB4_RS09690 b2ed917588f1b9b22132fff96a2657ff 168 Pfam PF06271 RDD family 2 141 7.9E-27 T 29-03-2018 IPR010432 RDD CB4_RS07465 a4ad6e4bf702dc7b058f228927f455a5 249 SUPERFAMILY SSF161098 53 233 8.11E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS07465 a4ad6e4bf702dc7b058f228927f455a5 249 Gene3D G3DSA:1.10.3720.10 48 249 2.8E-22 T 29-03-2018 CB4_RS07465 a4ad6e4bf702dc7b058f228927f455a5 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 246 2.5E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CB4_RS14035 f63c15407ad3d7d534d3582adbf00d5a 205 Pfam PF03458 UPF0126 domain 5 76 5.4E-19 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CB4_RS14035 f63c15407ad3d7d534d3582adbf00d5a 205 Pfam PF03458 UPF0126 domain 92 161 2.9E-19 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CB4_RS13525 6f3c933e5a88b5ac944b89bf4e076089 250 Pfam PF12730 ABC-2 family transporter protein 10 185 1.3E-14 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CB4_RS19150 f7075e07c0be2e16700ba4f2ac4fc468 117 Pfam PF13248 zinc-ribbon domain 86 111 9.4E-9 T 29-03-2018 CB4_RS19150 f7075e07c0be2e16700ba4f2ac4fc468 117 Gene3D G3DSA:2.20.28.20 85 116 1.4E-6 T 29-03-2018 CB4_RS14140 a2718c733671e3a6a93aded42b98efca 147 Gene3D G3DSA:3.40.190.10 1 144 7.1E-4 T 29-03-2018 CB4_RS04850 2adeda9e2d6da53fae44e72c7b22ca5b 126 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 6 114 3.8E-35 T 29-03-2018 IPR018745 Domain of unknown function DUF2294 CB4_RS00615 9eea3423bee73fb19b3a954ebbccdfde 434 Pfam PF07949 YbbR-like protein 233 311 2.3E-14 T 29-03-2018 IPR012505 YbbR-like CB4_RS00615 9eea3423bee73fb19b3a954ebbccdfde 434 Pfam PF07949 YbbR-like protein 59 131 1.2E-9 T 29-03-2018 IPR012505 YbbR-like CB4_RS00615 9eea3423bee73fb19b3a954ebbccdfde 434 Pfam PF07949 YbbR-like protein 141 223 7.7E-8 T 29-03-2018 IPR012505 YbbR-like CB4_RS11055 fc7651cb329909a2e8c81f462f1c701f 245 Gene3D G3DSA:2.130.10.130 11 209 1.1E-5 T 29-03-2018 CB4_RS11055 fc7651cb329909a2e8c81f462f1c701f 245 SUPERFAMILY SSF69318 18 209 8.24E-10 T 29-03-2018 CB4_RS12620 39baa7d043b4805a60139156bff4df71 157 Gene3D G3DSA:1.20.1170.10 3 152 9.8E-8 T 29-03-2018 CB4_RS02690 a4f8a43c65895784ff37885382ddec31 74 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 23 74 1.0E-4 T 29-03-2018 CB4_RS02690 a4f8a43c65895784ff37885382ddec31 74 Pfam PF07293 Protein of unknown function (DUF1450) 8 73 2.0E-11 T 29-03-2018 IPR009910 Protein of unknown function DUF1450 CB4_RS14660 0e2ce1b4c15928193b6616c4e17d9e40 137 Pfam PF08896 Domain of unknown function (DUF1842) 7 120 1.3E-30 T 29-03-2018 IPR014992 Domain of unknown function DUF1842 CB4_RS08150 c3214b039715157ae45f80d5952aed57 382 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 67 312 3.3E-47 T 29-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 CB4_RS08150 c3214b039715157ae45f80d5952aed57 382 SUPERFAMILY SSF53335 18 372 7.34E-86 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CB4_RS08735 31f7af020ed042c48bb94e51f4287d28 165 Gene3D G3DSA:3.90.20.10 9 144 6.7E-7 T 29-03-2018 CB4_RS04230 ae28b42b9fe33b71fc59d5d4fa009af8 362 Pfam PF03845 Spore germination protein 7 325 1.2E-61 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS04230 ae28b42b9fe33b71fc59d5d4fa009af8 362 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 361 1.1E-76 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CB4_RS19315 aa948c2e7f4acbad9e88f722b7c1d826 76 Pfam PF03672 Uncharacterised protein family (UPF0154) 8 64 9.7E-16 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 CB4_RS12750 94f92e2681bbfec5c60e969d7c2508c9 213 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 189 4.8E-7 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CB4_RS05240 a76ff4d4721e96a486e60542dd08a18f 120 Pfam PF12788 YmaF family 21 115 1.1E-37 T 29-03-2018 IPR024307 YmaF CB4_RS18160 445e9f84d42f0d93c9d625d55b48bca8 313 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 305 2.4E-54 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CB4_RS18160 445e9f84d42f0d93c9d625d55b48bca8 313 Gene3D G3DSA:1.10.3470.10 35 311 4.8E-42 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CB4_RS17435 2cbc95e198dc1f0633e7df2b9cd59e13 503 Pfam PF13552 Protein of unknown function (DUF4127) 25 497 2.5E-76 T 29-03-2018 IPR025394 Protein of unknown function DUF4127 CB4_RS13620 eb9dbdbb58d4f51b6df58645f05d8607 70 Pfam PF11213 Protein of unknown function (DUF3006) 3 69 1.1E-20 T 29-03-2018 IPR021377 Protein of unknown function DUF3006 CB4_RS18265 196e946ae08c9070aa991b0b0fb3943c 189 Gene3D G3DSA:3.40.190.10 1 186 2.1E-4 T 29-03-2018 CB4_RS18045 a612ba36bb0a27d50198d5dec9513af7 242 Pfam PF02754 Cysteine-rich domain 133 216 5.7E-15 T 29-03-2018 IPR004017 Cysteine-rich domain CB4_RS18045 a612ba36bb0a27d50198d5dec9513af7 242 Pfam PF02754 Cysteine-rich domain 3 84 4.1E-16 T 29-03-2018 IPR004017 Cysteine-rich domain CB4_RS14175 a34a66ded3bcdd6172842763ed7d0fc7 89 Pfam PF09855 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) 33 85 8.6E-5 T 29-03-2018 IPR018652 Protein of unknown function DUF2082, nucleic-acid-binding, Zn-ribbon CB4_RS16410 c8be8c33e42648eeed0563bca60323a1 357 Gene3D G3DSA:3.40.50.10240 179 264 8.6E-10 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CB4_RS16410 c8be8c33e42648eeed0563bca60323a1 357 SUPERFAMILY SSF63999 163 314 3.66E-24 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CB4_RS15760 b51e133b5de168917e3f5e0ce54fcd96 82 Pfam PF05433 Glycine zipper 2TM domain 23 59 2.0E-5 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 CB4_RS15360 a3f0d9108af2265c4480c47bde4876b5 71 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 11 65 7.1E-24 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CB4_RS15360 a3f0d9108af2265c4480c47bde4876b5 71 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 44 58 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CB4_RS09255 d99d0f34936f00a1908e3ea2c52b9ef7 163 Gene3D G3DSA:1.10.10.60 40 156 1.1E-6 T 29-03-2018 CB4_RS09890 7c736d59460c2de177caa518e3b2f197 462 Pfam PF00324 Amino acid permease 52 389 1.4E-33 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CB4_RS09890 7c736d59460c2de177caa518e3b2f197 462 PIRSF PIRSF006060 7 462 7.4E-63 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS16490 4b30f385823595ef0e801a6bb36cdc32 170 Pfam PF13490 Putative zinc-finger 4 35 1.3E-10 T 29-03-2018 IPR027383 Putative zinc-finger CB4_RS17875 eb396b4b6e305bc8833a9f26ebbcc06a 173 Pfam PF13798 Protein of unknown function with PCYCGC motif 14 168 3.8E-61 T 29-03-2018 IPR025673 Protein of unknown function with PCYCGC motif CB4_RS12170 bd7d227c970faffc197edadaebae7115 202 Pfam PF03458 UPF0126 domain 92 161 8.0E-18 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CB4_RS12170 bd7d227c970faffc197edadaebae7115 202 Pfam PF03458 UPF0126 domain 5 78 3.3E-14 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CB4_RS08525 4ee7ce56928d8c12de819d638045af2f 33 Pfam PF08183 Stage V sporulation protein family 10 30 1.3E-11 T 29-03-2018 IPR012609 Sporulation stage V, protein M CB4_RS19690 66179decb344dbde48431345cb76469b 61 Pfam PF17259 Family of unknown function (DUF5325) 1 61 1.3E-19 T 29-03-2018 IPR035211 Protein of unknown function DUF5325 CB4_RS20665 860f1d1d408ee9e6a7b645da40ea29d7 266 Pfam PF01618 MotA/TolQ/ExbB proton channel family 101 217 1.9E-23 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CB4_RS00280 130c1f7f2f36b9996a50da9f08748a42 120 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 5 114 2.1E-29 T 29-03-2018 IPR018745 Domain of unknown function DUF2294 CB4_RS15420 7ca8a5ab3e81462758e1b8e128381516 224 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 16 132 1.3E-8 T 29-03-2018 IPR018755 Bacteriophage Mu-like, Gp48 CB4_RS13270 ab7fa34622fa0c35214a4418bcf80a24 223 Pfam PF04012 PspA/IM30 family 2 214 1.5E-27 T 29-03-2018 IPR007157 PspA/IM30 CB4_RS02235 7c6a302d4f6ff82420ae5b9953a932d8 458 Gene3D G3DSA:1.25.20.10 59 447 8.4E-6 T 29-03-2018 CB4_RS12665 8108b76c3b793d4db3100ef752f76570 302 Pfam PF13536 Putative multidrug resistance efflux transporter 15 282 9.1E-107 T 29-03-2018 IPR032713 Putative multidrug resistance efflux transporter CB4_RS05435 263dc2fd18b7d443de4c30bf288bef18 444 Pfam PF04932 O-Antigen ligase 230 365 3.9E-16 T 29-03-2018 IPR007016 O-antigen ligase-related CB4_RS15060 542f146b86cb904aea62a5c54d719e21 209 Pfam PF13490 Putative zinc-finger 4 33 1.8E-8 T 29-03-2018 IPR027383 Putative zinc-finger CB4_RS11140 d071f2550f452406a7a30fef8ad3c27d 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 370 384 1.0E-13 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS11140 d071f2550f452406a7a30fef8ad3c27d 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 386 405 1.0E-13 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS11140 d071f2550f452406a7a30fef8ad3c27d 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 166 194 1.0E-13 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS11140 d071f2550f452406a7a30fef8ad3c27d 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 67 79 1.0E-13 T 29-03-2018 IPR003004 GspF/PilC family CB4_RS11140 d071f2550f452406a7a30fef8ad3c27d 405 Pfam PF00482 Type II secretion system (T2SS), protein F 276 397 3.1E-24 T 29-03-2018 IPR018076 Type II secretion system F domain CB4_RS11140 d071f2550f452406a7a30fef8ad3c27d 405 Pfam PF00482 Type II secretion system (T2SS), protein F 71 194 3.8E-22 T 29-03-2018 IPR018076 Type II secretion system F domain CB4_RS17395 9994579971a2efae83ca403dc1c2778e 196 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 58 187 1.8E-16 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CB4_RS03975 6539ec4bf66b332f340aefb6cdaad44d 656 Pfam PF02538 Hydantoinase B/oxoprolinase 13 537 5.2E-147 T 29-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 CB4_RS14115 496a7ee7457489f290e327f9752a95b2 245 Pfam PF04402 Protein of unknown function (DUF541) 40 243 9.3E-47 T 29-03-2018 IPR007497 Protein of unknown function DUF541 CB4_RS04690 9e6f281e1045d2a3c9650fbf83147e27 79 ProDom PD058325 YUSG BH3483 6 79 1.0E-4 T 29-03-2018 IPR020140 Uncharacterised protein family YusG CB4_RS04690 9e6f281e1045d2a3c9650fbf83147e27 79 Pfam PF10830 Protein of unknown function (DUF2553) 8 79 6.0E-15 T 29-03-2018 IPR020140 Uncharacterised protein family YusG CB4_RS13225 d43b21679b15de88cbe2d24b4146079a 199 Pfam PF11193 Protein of unknown function (DUF2812) 9 119 8.3E-24 T 29-03-2018 IPR021359 Protein of unknown function DUF2812 CB4_RS18845 78e689b2680761bc391c603f2b2f1b56 482 Pfam PF01385 Probable transposase 213 340 2.1E-7 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CB4_RS09285 16b6a7e82565bde440008cb4c7ffb260 257 Pfam PF01148 Cytidylyltransferase family 2 255 6.4E-65 T 29-03-2018 CB4_RS06310 b633264a09328d26bc527dd7071fe3fa 222 Gene3D G3DSA:1.10.287.700 2 154 1.7E-5 T 29-03-2018 CB4_RS03380 a549447a63141d393255317433d8b5a9 243 Gene3D G3DSA:3.40.50.2020 68 243 2.1E-24 T 29-03-2018 CB4_RS03380 a549447a63141d393255317433d8b5a9 243 SUPERFAMILY SSF53271 68 230 3.41E-23 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CB4_RS04310 e1fefe48d7a2db6cd24e62e03ad0217a 255 Pfam PF14014 Protein of unknown function (DUF4230) 100 249 4.4E-25 T 29-03-2018 IPR025324 Protein of unknown function DUF4230 CB4_RS04065 e1684f35d9634bdc6eb33c51b585dbc3 332 Pfam PF02628 Cytochrome oxidase assembly protein 69 301 4.8E-22 T 29-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CB4_RS13140 8dae892b5e9e6ae79ea66bbfdec1dd26 361 Pfam PF04235 Protein of unknown function (DUF418) 200 359 4.6E-16 T 29-03-2018 IPR007349 Domain of unknown function DUF418 CB4_RS09950 5722dc7e35a4f43777180a6ccf837dbf 106 Pfam PF02583 Metal-sensitive transcriptional repressor 24 100 2.5E-29 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CB4_RS19910 a7cf326172ca7714f9dd80fcde2f5ab6 608 Pfam PF13520 Amino acid permease 38 440 2.4E-26 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CB4_RS18485 402a05a9bbe71c15b6582949082765bc 317 ProDom PD210561 YWRJ 15 149 5.0E-7 T 29-03-2018 IPR020173 Uncharacterised protein family YwrJ CB4_RS16770 55ad490f69232cb7d12575bada7a7fc7 311 Pfam PF03547 Membrane transport protein 161 302 3.3E-9 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CB4_RS16770 55ad490f69232cb7d12575bada7a7fc7 311 Pfam PF03547 Membrane transport protein 8 151 1.2E-14 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CB4_RS07050 a5e3932c7843b1023aeb83a9f30716ac 136 Pfam PF04134 Protein of unknown function, DUF393 10 119 9.1E-37 T 29-03-2018 IPR007263 Protein of unknown function DUF393 CB4_RS17440 a271da0a84c4b20c6e743bd9e0344194 146 Gene3D G3DSA:3.30.160.60 118 142 0.0061 T 29-03-2018 CB4_RS02485 e2a2b8a2bc05368bba67c0f127442a65 243 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 21 208 2.6E-45 T 29-03-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein CB4_RS20545 a891fd7b1f8a6eae7809e0699bccbf9c 181 Gene3D G3DSA:3.90.20.10 10 84 6.1E-4 T 29-03-2018 CB4_RS16730 d66c9c4a11b727d5b4fc96b64360ee7e 330 Pfam PF12679 ABC-2 family transporter protein 7 328 8.1E-26 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CB4_RS09805 254aeabcde04a9f9c3d9945f3e9190d7 257 Pfam PF14042 Domain of unknown function (DUF4247) 21 196 8.3E-31 T 29-03-2018 IPR025341 Protein of unknown function DUF4247