locus-tag	class	description
BBF96_RS00040	COG3885	ferrous iron binding
BBF96_RS00040	COG2078	PFAM AMMECR1 domain protein
BBF96_RS00045	COG0697	spore germination
BBF96_RS00065	COG1063	alcohol dehydrogenase
BBF96_RS00070	COG0156	8-amino-7-oxononanoate synthase activity
BBF96_RS00075	COG1595	DNA-templated transcription, initiation
BBF96_RS00100	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BBF96_RS00110	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BBF96_RS00115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBF96_RS00120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBF96_RS00195	COG0129	dihydroxy-acid dehydratase activity
BBF96_RS00205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBF96_RS00210	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BBF96_RS00215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBF96_RS00220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBF96_RS00235	COG3875	lactate racemase activity
BBF96_RS00240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBF96_RS00245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBF96_RS00250	COG0800	Aldolase
BBF96_RS00255	COG1414	Transcriptional regulator
BBF96_RS00265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBF96_RS00280	COG0736	holo-[acyl-carrier-protein] synthase activity
BBF96_RS00285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BBF96_RS00285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BBF96_RS00290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBF96_RS00295	COG1073	alpha beta
BBF96_RS00310	COG2337	Toxic component of a toxin-antitoxin (TA) module
BBF96_RS00320	COG1473	amidohydrolase
BBF96_RS00330	COG1228	amidohydrolase
BBF96_RS00345	COG0802	atpase or kinase
BBF96_RS00350	COG1214	PFAM Peptidase M22, glycoprotease
BBF96_RS00355	COG0456	acetyltransferase
BBF96_RS00360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBF96_RS00370	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BBF96_RS00375	COG0459	protein refolding
BBF96_RS00380	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BBF96_RS00385	COG1131	(ABC) transporter
BBF96_RS00400	COG1404	Belongs to the peptidase S8 family
BBF96_RS00405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BBF96_RS00405	COG0519	Catalyzes the synthesis of GMP from XMP
BBF96_RS00410	COG2252	PERMEase
BBF96_RS00430	COG0521	Mo-molybdopterin cofactor biosynthetic process
BBF96_RS00435	COG3457	Alanine racemase
BBF96_RS00440	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBF96_RS00445	COG4496	protein, YerC YecD
BBF96_RS00450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBF96_RS00455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBF96_RS00460	COG2011	ABC-type metal ion transport system permease component
BBF96_RS00470	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BBF96_RS00485	COG1091	dTDP-4-dehydrorhamnose reductase activity
BBF96_RS00490	COG0438	transferase activity, transferring glycosyl groups
BBF96_RS00500	COG0438	transferase activity, transferring glycosyl groups
BBF96_RS00500	COG1216	Glycosyl transferase, family 2
BBF96_RS00510	COG1216	Glycosyl transferase, family 2
BBF96_RS00510	COG0438	transferase activity, transferring glycosyl groups
BBF96_RS00515	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BBF96_RS00520	COG4641	Protein conserved in bacteria
BBF96_RS00530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBF96_RS00535	COG1280	lysine exporter protein (LysE YggA)
BBF96_RS00675	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BBF96_RS00680	COG0617	tRNA 3'-terminal CCA addition
BBF96_RS00690	COG0765	amino acid transport
BBF96_RS00700	COG1131	(ABC) transporter
BBF96_RS00705	COG1122	ATPase activity
BBF96_RS00720	COG1131	(ABC) transporter
BBF96_RS00735	COG3845	ABC transporter
BBF96_RS00740	COG4603	Belongs to the binding-protein-dependent transport system permease family
BBF96_RS00745	COG1079	Belongs to the binding-protein-dependent transport system permease family
BBF96_RS00760	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BBF96_RS00775	COG0824	Thioesterase
BBF96_RS00820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBF96_RS00830	COG0739	heme binding
BBF96_RS00835	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BBF96_RS00845	COG0154	amidase activity
BBF96_RS00850	COG0454	-acetyltransferase
BBF96_RS00855	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBF96_RS00895	COG0673	inositol 2-dehydrogenase activity
BBF96_RS00900	COG0318	PFAM AMP-dependent synthetase and ligase
BBF96_RS00905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBF96_RS00910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBF96_RS00925	COG0534	Mate efflux family protein
BBF96_RS00935	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBF96_RS00945	COG1309	transcriptional regulator
BBF96_RS00950	COG3848	Pyruvate phosphate dikinase
BBF96_RS00950	COG0574	Belongs to the PEP-utilizing enzyme family
BBF96_RS00955	COG2814	Major facilitator Superfamily
BBF96_RS00970	COG0697	spore germination
BBF96_RS00975	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BBF96_RS00980	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BBF96_RS00985	COG1984	allophanate hydrolase subunit 2
BBF96_RS01015	COG1164	Oligoendopeptidase f
BBF96_RS01020	COG0737	Belongs to the 5'-nucleotidase family
BBF96_RS01040	COG1131	(ABC) transporter
BBF96_RS01055	COG1131	(ABC) transporter
BBF96_RS01065	COG0500	methyltransferase
BBF96_RS01075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BBF96_RS01090	COG2005	Transcriptional regulator
BBF96_RS01095	COG0725	ABC transporter, periplasmic molybdate-binding protein
BBF96_RS01100	COG4149	molybdate abc transporter
BBF96_RS01110	COG0017	Asparaginyl-tRNA synthetase
BBF96_RS01115	COG0697	spore germination
BBF96_RS01120	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BBF96_RS01135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBF96_RS01140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BBF96_RS01170	COG0564	pseudouridine synthase activity
BBF96_RS01175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BBF96_RS01180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBF96_RS01185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBF96_RS01190	COG1404	Belongs to the peptidase S8 family
BBF96_RS01200	COG1404	Belongs to the peptidase S8 family
BBF96_RS01205	COG1032	radical SAM domain protein
BBF96_RS01210	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BBF96_RS01220	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBF96_RS01230	COG2431	L-lysine efflux transmembrane transporter activity
BBF96_RS01240	COG1132	(ABC) transporter
BBF96_RS01245	COG1132	(ABC) transporter
BBF96_RS01270	COG4134	Bacterial extracellular solute-binding protein
BBF96_RS01275	COG1176	ABC-type spermidine putrescine transport system, permease component I
BBF96_RS01280	COG4208	sulfate ABC transporter
BBF96_RS01285	COG3842	ATPase activity
BBF96_RS01295	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BBF96_RS01295	COG2508	Transcriptional regulator
BBF96_RS01310	COG2391	methyltransferase activity
BBF96_RS01320	COG2897	thiosulfate sulfurtransferase activity
BBF96_RS01325	COG0398	Pfam SNARE associated Golgi protein
BBF96_RS01420	COG2199	diguanylate cyclase activity
BBF96_RS01420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BBF96_RS01430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BBF96_RS01435	COG0840	transmembrane signaling receptor activity
BBF96_RS01440	COG1136	(ABC) transporter
BBF96_RS01445	COG0577	efflux transmembrane transporter activity
BBF96_RS01445	COG1136	(ABC) transporter
BBF96_RS01450	COG4591	ABC-type transport system involved in lipoprotein release permease component
BBF96_RS01475	COG1940	carbohydrate kinase activity
BBF96_RS01475	COG1846	Transcriptional regulator
BBF96_RS01480	COG1082	Xylose isomerase domain protein TIM barrel
BBF96_RS01485	COG1070	Carbohydrate kinase
BBF96_RS01490	COG4213	ABC transporter substrate-binding protein
BBF96_RS01500	COG4214	carbohydrate transport
BBF96_RS01515	COG0653	protein targeting
BBF96_RS01530	COG0840	transmembrane signaling receptor activity
BBF96_RS01535	COG0215	cysteine-tRNA ligase activity
BBF96_RS01560	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BBF96_RS01565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBF96_RS01570	COG3959	Transketolase, thiamine diphosphate binding domain
BBF96_RS01575	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBF96_RS01585	COG0793	Belongs to the peptidase S41A family
BBF96_RS01600	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBF96_RS01600	COG2247	cell wall binding repeat
BBF96_RS01620	COG0622	Phosphoesterase
BBF96_RS01630	COG0556	nucleotide-excision repair
BBF96_RS01635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBF96_RS01650	COG2182	Extracellular solute-binding protein
BBF96_RS01655	COG1175	transmembrane transport
BBF96_RS01660	COG3833	ABC-type maltose transport systems, permease component
BBF96_RS01665	COG0366	Alpha amylase catalytic
BBF96_RS01670	COG0322	excinuclease ABC activity
BBF96_RS01675	COG1175	transmembrane transport
BBF96_RS01680	COG0395	ABC-type sugar transport system, permease component
BBF96_RS01695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBF96_RS01720	COG1950	PFAM Membrane protein of
BBF96_RS01730	COG1937	Protein conserved in bacteria
BBF96_RS01735	COG2217	Heavy metal translocating P-type atpase
BBF96_RS01740	COG3086	response to oxidative stress
BBF96_RS01745	COG2608	mercury ion transmembrane transporter activity
BBF96_RS01760	COG0644	oxidoreductase
BBF96_RS01765	COG0561	phosphatase activity
BBF96_RS01770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBF96_RS01775	COG0438	transferase activity, transferring glycosyl groups
BBF96_RS01795	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BBF96_RS01835	COG2264	protein methyltransferase activity
BBF96_RS01845	COG1543	Belongs to the glycosyl hydrolase 57 family
BBF96_RS01850	COG0438	transferase activity, transferring glycosyl groups
BBF96_RS01855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BBF96_RS01880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBF96_RS01925	COG1575	Belongs to the MenA family. Type 1 subfamily
BBF96_RS01935	COG1131	(ABC) transporter
BBF96_RS01945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBF96_RS01965	COG1660	Displays ATPase and GTPase activities
BBF96_RS01970	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BBF96_RS01975	COG1481	regulation of sporulation
BBF96_RS02020	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BBF96_RS02025	COG0148	phosphopyruvate hydratase activity
BBF96_RS02030	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBF96_RS02035	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BBF96_RS02050	COG0778	Nitroreductase
BBF96_RS02060	COG0557	exoribonuclease II activity
BBF96_RS02065	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BBF96_RS02080	COG0840	transmembrane signaling receptor activity
BBF96_RS02090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBF96_RS02115	COG2390	Transcriptional regulator
BBF96_RS02120	COG4869	propanediol catabolic process
BBF96_RS02125	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BBF96_RS02145	COG4656	Part of a membrane complex involved in electron transport
BBF96_RS02160	COG0698	ribose 5-phosphate isomerase
BBF96_RS02175	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBF96_RS02220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBF96_RS02235	COG0697	spore germination
BBF96_RS02250	COG1924	4 iron, 4 sulfur cluster binding
BBF96_RS02255	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BBF96_RS02260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BBF96_RS02265	COG0747	negative chemotaxis
BBF96_RS02270	COG0601	transmembrane transport
BBF96_RS02275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_RS02280	COG0617	tRNA 3'-terminal CCA addition
BBF96_RS02280	COG3620	sequence-specific DNA binding
BBF96_RS02280	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BBF96_RS02295	COG0180	Tryptophanyl-tRNA synthetase
BBF96_RS02300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BBF96_RS02305	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBF96_RS02315	COG3874	Sporulation protein YtfJ
BBF96_RS02320	COG1686	Belongs to the peptidase S11 family
BBF96_RS02335	COG1122	ATPase activity
BBF96_RS02340	COG1187	pseudouridine synthase activity
BBF96_RS02345	COG2359	stage V sporulation protein S
BBF96_RS02350	COG1196	nuclear chromosome segregation
BBF96_RS02360	COG0552	protein localization to endoplasmic reticulum
BBF96_RS02415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBF96_RS02420	COG0228	four-way junction DNA binding
BBF96_RS02430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BBF96_RS02435	COG0336	Belongs to the RNA methyltransferase TrmD family
BBF96_RS02445	COG0681	Belongs to the peptidase S26 family
BBF96_RS02470	COG0606	chelatase, subunit chli
BBF96_RS02475	COG0792	nuclease activity
BBF96_RS02485	COG0758	DNA mediated transformation
BBF96_RS02485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBF96_RS02495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBF96_RS02500	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BBF96_RS02505	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BBF96_RS02510	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BBF96_RS02520	COG2201	protein-glutamate methylesterase activity
BBF96_RS02525	COG0643	Histidine kinase
BBF96_RS02525	COG2198	Histidine kinase
BBF96_RS02530	COG0835	chemotaxis
BBF96_RS02535	COG1776	CheC inhibitor of MCP methylation
BBF96_RS02540	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BBF96_RS02545	COG0052	Belongs to the universal ribosomal protein uS2 family
BBF96_RS02550	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BBF96_RS02555	COG0528	UMP kinase activity
BBF96_RS02560	COG0233	cytoplasmic translational termination
BBF96_RS02570	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BBF96_RS02575	COG0575	Belongs to the CDS family
BBF96_RS02580	COG0628	permease
BBF96_RS02585	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BBF96_RS02590	COG0750	zinc metalloprotease
BBF96_RS02600	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BBF96_RS02605	COG0442	prolyl-tRNA aminoacylation
BBF96_RS02610	COG0463	Glycosyl transferase, family 2
BBF96_RS02615	COG1285	pathogenesis
BBF96_RS02620	COG2814	Major facilitator Superfamily
BBF96_RS02655	COG1132	(ABC) transporter
BBF96_RS02660	COG0779	Required for maturation of 30S ribosomal subunits
BBF96_RS02665	COG0195	Participates in both transcription termination and antitermination
BBF96_RS02670	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BBF96_RS02680	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BBF96_RS02685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BBF96_RS02690	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BBF96_RS02695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BBF96_RS02700	COG0196	riboflavin kinase activity
BBF96_RS02715	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BBF96_RS02720	COG1185	polyribonucleotide nucleotidyltransferase activity
BBF96_RS02725	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BBF96_RS02730	COG1199	ATP-dependent helicase activity
BBF96_RS02740	COG3706	GGDEF domain
BBF96_RS02755	COG0726	polysaccharide deacetylase
BBF96_RS02760	COG2720	vancomycin resistance protein
BBF96_RS02795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBF96_RS02800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBF96_RS02805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BBF96_RS02810	COG0527	aspartate kinase activity
BBF96_RS02815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBF96_RS02820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBF96_RS02825	COG1353	crispr-associated protein
BBF96_RS02835	COG1337	RAMP superfamily
BBF96_RS02860	COG0011	TIGRFAM Protein of
BBF96_RS02865	COG0740	serine-type endopeptidase activity
BBF96_RS02875	COG1283	sodium-dependent phosphate transmembrane transporter activity
BBF96_RS02880	COG1968	undecaprenyl-diphosphatase activity
BBF96_RS02890	COG1674	ftsk spoiiie
BBF96_RS02895	COG2188	Transcriptional regulator
BBF96_RS02900	COG1744	ABC transporter substrate-binding protein PnrA-like
BBF96_RS02905	COG3845	ABC transporter
BBF96_RS02910	COG4603	Belongs to the binding-protein-dependent transport system permease family
BBF96_RS02915	COG1079	Belongs to the binding-protein-dependent transport system permease family
BBF96_RS02925	COG1426	Protein conserved in bacteria
BBF96_RS02955	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBF96_RS03020	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BBF96_RS03030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBF96_RS03045	COG2814	Major facilitator Superfamily
BBF96_RS03050	COG0423	glycine-tRNA ligase activity
BBF96_RS03095	COG4152	abc transporter atp-binding protein
BBF96_RS03135	COG0436	Aminotransferase
BBF96_RS03150	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BBF96_RS03160	COG4942	peptidase
BBF96_RS03185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBF96_RS03190	COG1012	belongs to the aldehyde dehydrogenase family
BBF96_RS03195	COG0840	transmembrane signaling receptor activity
BBF96_RS03205	COG3191	aminopeptidase activity
BBF96_RS03225	COG0582	viral genome integration into host DNA
BBF96_RS03295	COG3800	Transcriptional regulator
BBF96_RS03295	COG1396	sequence-specific DNA binding
BBF96_RS03355	COG0514	ATP-dependent DNA helicase (RecQ)
BBF96_RS03385	COG0629	single-stranded DNA binding
BBF96_RS03560	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBF96_RS03630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBF96_RS03635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBF96_RS03640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BBF96_RS03675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBF96_RS03690	COG0626	cystathionine gamma-synthase activity
BBF96_RS03695	COG1982	Orn Lys Arg decarboxylase major
BBF96_RS03700	COG1058	Belongs to the CinA family
BBF96_RS03700	COG1546	Belongs to the CinA family
BBF96_RS03705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBF96_RS03765	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BBF96_RS03770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BBF96_RS03780	COG1418	mRNA catabolic process
BBF96_RS03790	COG1692	metallophosphoesterase
BBF96_RS03795	COG2359	stage V sporulation protein S
BBF96_RS03840	COG0601	transmembrane transport
BBF96_RS03845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_RS03855	COG0840	transmembrane signaling receptor activity
BBF96_RS03895	COG3546	catalase activity
BBF96_RS03900	COG1252	NADH dehydrogenase
BBF96_RS03930	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BBF96_RS03945	COG1573	uracil-dna glycosylase
BBF96_RS03955	COG0116	Belongs to the methyltransferase superfamily
BBF96_RS03960	COG1067	ATP-dependent peptidase activity
BBF96_RS03970	COG0864	Transcriptional regulator
BBF96_RS03975	COG0310	cobalt ion transport
BBF96_RS03990	COG1122	ATPase activity
BBF96_RS03995	COG2715	membrane protein required for spore maturation
BBF96_RS04000	COG0700	Nucleoside recognition
BBF96_RS04005	COG0613	PHP domain protein
BBF96_RS04015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBF96_RS04020	COG0811	peptide transport
BBF96_RS04025	COG0848	biopolymer transport protein
BBF96_RS04060	COG1278	Cold shock
BBF96_RS04070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBF96_RS04075	COG0187	DNA topoisomerase II activity
BBF96_RS04080	COG2247	cell wall binding repeat
BBF96_RS04080	COG2385	sporulation resulting in formation of a cellular spore
BBF96_RS04085	COG2217	Heavy metal translocating P-type atpase
BBF96_RS04090	COG0640	Transcriptional regulator
BBF96_RS04095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBF96_RS04110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBF96_RS04115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BBF96_RS04115	COG2199	diguanylate cyclase activity
BBF96_RS04120	COG0826	peptidase U32
BBF96_RS04150	COG1183	phosphatidylcholine synthase activity
BBF96_RS04155	COG0688	phosphatidylethanolamine metabolic process
BBF96_RS04160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBF96_RS04180	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBF96_RS04185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BBF96_RS04190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBF96_RS04200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBF96_RS04205	COG0534	Mate efflux family protein
BBF96_RS04210	COG0823	Involved in the tonB-independent uptake of proteins
BBF96_RS04210	COG1506	peptidase
BBF96_RS04210	COG4946	Tricorn protease homolog
BBF96_RS04215	COG3852	Histidine kinase
BBF96_RS04220	COG3973	AAA domain
BBF96_RS04235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BBF96_RS04270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BBF96_RS04295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBF96_RS04305	COG0511	ligase activity, forming carbon-carbon bonds
BBF96_RS04310	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BBF96_RS04315	COG2508	Transcriptional regulator
BBF96_RS04325	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BBF96_RS04335	COG1304	FMN binding
BBF96_RS04350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBF96_RS04355	COG0778	Nitroreductase
BBF96_RS04385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BBF96_RS04390	COG1410	methionine synthase
BBF96_RS04390	COG0646	methionine synthase
BBF96_RS04405	COG0778	Nitroreductase
BBF96_RS04415	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BBF96_RS04420	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BBF96_RS04425	COG0402	S-adenosylhomocysteine deaminase activity
BBF96_RS04430	COG2003	Belongs to the UPF0758 family
BBF96_RS04435	COG1309	transcriptional regulator
BBF96_RS04445	COG1566	PFAM secretion protein HlyD family protein
BBF96_RS04475	COG1132	(ABC) transporter
BBF96_RS04480	COG0445	tRNA wobble uridine modification
BBF96_RS04485	COG2304	oxidoreductase activity
BBF96_RS04490	COG1615	UPF0182 protein
BBF96_RS04495	COG0612	Peptidase, M16
BBF96_RS04500	COG0612	Peptidase, M16
BBF96_RS04505	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BBF96_RS04510	COG0477	Major facilitator Superfamily
BBF96_RS04520	COG0733	neurotransmitter:sodium symporter activity
BBF96_RS04535	COG1760	l-serine dehydratase
BBF96_RS04540	COG1760	l-serine dehydratase
BBF96_RS04545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BBF96_RS04555	COG0546	phosphoglycolate phosphatase activity
BBF96_RS04560	COG0012	GTP binding
BBF96_RS04565	COG1307	EDD domain protein, DegV family
BBF96_RS04605	COG1846	Transcriptional regulator
BBF96_RS04615	COG3314	Sporulation integral membrane protein YlbJ
BBF96_RS04620	COG0165	Argininosuccinate lyase
BBF96_RS04630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BBF96_RS04645	COG2226	methyltransferase
BBF96_RS04655	COG1752	Esterase of the alpha-beta hydrolase superfamily
BBF96_RS04660	COG3480	Lon protease (S16) C-terminal proteolytic domain
BBF96_RS04670	COG1323	Belongs to the UPF0348 family
BBF96_RS04675	COG0280	phosphate acetyltransferase
BBF96_RS04680	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBF96_RS04685	COG1399	metal-binding, possibly nucleic acid-binding protein
BBF96_RS04690	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BBF96_RS04695	COG2030	dehydratase
BBF96_RS04705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBF96_RS04710	COG2070	2-Nitropropane dioxygenase
BBF96_RS04715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BBF96_RS04720	COG1028	Short-chain dehydrogenase reductase Sdr
BBF96_RS04730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBF96_RS04745	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BBF96_RS04755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BBF96_RS04755	COG0539	negative regulation of cytoplasmic translation
BBF96_RS04765	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBF96_RS04790	COG0750	zinc metalloprotease
BBF96_RS04795	COG1160	GTP binding
BBF96_RS04800	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BBF96_RS04805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BBF96_RS04810	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BBF96_RS04820	COG0776	regulation of translation
BBF96_RS04825	COG0569	domain protein
BBF96_RS04850	COG0840	transmembrane signaling receptor activity
BBF96_RS04855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBF96_RS04855	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BBF96_RS04860	COG0564	pseudouridine synthase activity
BBF96_RS04880	COG1363	Peptidase, m42
BBF96_RS04885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBF96_RS04915	COG1309	transcriptional regulator
BBF96_RS04930	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BBF96_RS04935	COG2002	toxin-antitoxin pair type II binding
BBF96_RS04940	COG0840	transmembrane signaling receptor activity
BBF96_RS04955	COG0113	porphobilinogen synthase activity
BBF96_RS04960	COG0464	growth
BBF96_RS04980	COG1923	regulation of RNA biosynthetic process
BBF96_RS04985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BBF96_RS04990	COG0436	Aminotransferase
BBF96_RS04995	COG2031	fatty acid transporter
BBF96_RS05005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBF96_RS05010	COG1116	anion transmembrane transporter activity
BBF96_RS05015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBF96_RS05020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BBF96_RS05050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBF96_RS05055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBF96_RS05060	COG0667	Aldo Keto reductase
BBF96_RS05070	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BBF96_RS05075	COG4770	biotin carboxylase activity
BBF96_RS05085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBF96_RS05090	COG0346	lactoylglutathione lyase activity
BBF96_RS05095	COG1703	isobutyryl-CoA mutase activity
BBF96_RS05100	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBF96_RS05100	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBF96_RS05105	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBF96_RS05105	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBF96_RS05115	COG1013	pyruvate-flavodoxin oxidoreductase activity
BBF96_RS05120	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BBF96_RS05120	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBF96_RS05135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBF96_RS05150	COG2814	Major facilitator Superfamily
BBF96_RS05155	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBF96_RS05155	COG1013	pyruvate-flavodoxin oxidoreductase activity
BBF96_RS05155	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BBF96_RS05155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BBF96_RS05160	COG0534	Mate efflux family protein
BBF96_RS05200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBF96_RS05205	COG1388	LysM domain
BBF96_RS05205	COG0791	NLP P60 protein
BBF96_RS05230	COG1363	Peptidase, m42
BBF96_RS05235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BBF96_RS05240	COG2226	methyltransferase
BBF96_RS05255	COG3773	Cell wall hydrolase
BBF96_RS05255	COG3409	Peptidoglycan-binding domain 1 protein
BBF96_RS05270	COG1067	ATP-dependent peptidase activity
BBF96_RS05280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BBF96_RS05285	COG2086	electron transfer activity
BBF96_RS05300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBF96_RS05305	COG1085	galactose-1-phosphate uridylyltransferase
BBF96_RS05310	COG0438	transferase activity, transferring glycosyl groups
BBF96_RS05325	COG1653	transport
BBF96_RS05330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBF96_RS05345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBF96_RS05350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBF96_RS05350	COG1796	DNA polymerase
BBF96_RS05355	COG0546	phosphoglycolate phosphatase activity
BBF96_RS05405	COG1131	(ABC) transporter
BBF96_RS05430	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBF96_RS05435	COG0742	ribosomal rna small subunit methyltransferase
BBF96_RS05440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBF96_RS05445	COG1461	Dihydroxyacetone kinase
BBF96_RS05450	COG1302	Protein conserved in bacteria
BBF96_RS05455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BBF96_RS05460	COG2116	formate transmembrane transporter activity
BBF96_RS05465	COG0746	molybdenum cofactor guanylyltransferase activity
BBF96_RS05495	COG3118	belongs to the thioredoxin family
BBF96_RS05510	COG0281	malic enzyme
BBF96_RS05515	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BBF96_RS05550	COG0587	DNA-directed DNA polymerase activity
BBF96_RS05560	COG0312	modulator of DNA gyrase
BBF96_RS05585	COG2610	gluconate transmembrane transporter activity
BBF96_RS05590	COG1929	Belongs to the glycerate kinase type-1 family
BBF96_RS05595	COG3835	regulator
BBF96_RS05600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBF96_RS05605	COG0095	Lipoate-protein ligase
BBF96_RS05610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BBF96_RS05620	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BBF96_RS05625	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BBF96_RS05630	COG0509	glycine decarboxylation via glycine cleavage system
BBF96_RS05635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BBF96_RS05640	COG0823	Involved in the tonB-independent uptake of proteins
BBF96_RS05655	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
BBF96_RS05660	COG1113	amino acid transport
BBF96_RS05665	COG0501	Belongs to the peptidase M48B family
BBF96_RS05670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBF96_RS05675	COG1328	CTP reductase activity
BBF96_RS05680	COG0835	chemotaxis
BBF96_RS05695	COG1074	ATP-dependent DNA helicase activity
BBF96_RS05715	COG1363	Peptidase, m42
BBF96_RS05720	COG1404	Belongs to the peptidase S8 family
BBF96_RS05740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BBF96_RS05745	COG1956	GAF domain-containing protein
BBF96_RS05755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_RS05760	COG0601	transmembrane transport
BBF96_RS05765	COG0747	negative chemotaxis
BBF96_RS05775	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BBF96_RS05790	COG0142	geranyltranstransferase activity
BBF96_RS05810	COG0298	carbon dioxide binding
BBF96_RS05815	COG0805	protein transport
BBF96_RS05820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBF96_RS05825	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BBF96_RS05850	COG2226	methyltransferase
BBF96_RS05865	COG3859	Proton-coupled thiamine transporter YuaJ
BBF96_RS05875	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBF96_RS05875	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBF96_RS05880	COG0307	riboflavin synthase, alpha
BBF96_RS05885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBF96_RS05885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBF96_RS05890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBF96_RS05895	COG1162	GTPase activity
BBF96_RS05900	COG2815	serine threonine protein kinase
BBF96_RS05900	COG0515	serine threonine protein kinase
BBF96_RS05905	COG0631	protein serine/threonine phosphatase activity
BBF96_RS05915	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BBF96_RS05920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBF96_RS05920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBF96_RS05930	COG2738	Putative neutral zinc metallopeptidase
BBF96_RS05940	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BBF96_RS05945	COG0242	peptide deformylase activity
BBF96_RS05950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBF96_RS05960	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBF96_RS05970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BBF96_RS05975	COG1489	DNA binding
BBF96_RS05980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BBF96_RS05985	COG0366	Alpha amylase catalytic
BBF96_RS05990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBF96_RS05995	COG1758	RNA polymerase activity
BBF96_RS06000	COG0194	GDP metabolic process
BBF96_RS06010	COG1561	YicC-like family, N-terminal region
BBF96_RS06025	COG0577	efflux transmembrane transporter activity
BBF96_RS06025	COG1136	(ABC) transporter
BBF96_RS06035	COG1136	(ABC) transporter
BBF96_RS06035	COG0577	efflux transmembrane transporter activity
BBF96_RS06070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBF96_RS06075	COG1694	Mazg nucleotide pyrophosphohydrolase
BBF96_RS06085	COG0123	including yeast histone deacetylase and acetoin utilization protein
BBF96_RS06145	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BBF96_RS06150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BBF96_RS06155	COG0167	dihydroorotate dehydrogenase activity
BBF96_RS06160	COG0543	2 iron, 2 sulfur cluster binding
BBF96_RS06165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BBF96_RS06175	COG0284	orotidine-5'-phosphate decarboxylase activity
BBF96_RS06180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBF96_RS06185	COG0540	Belongs to the ATCase OTCase family
BBF96_RS06190	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BBF96_RS06195	COG0564	pseudouridine synthase activity
BBF96_RS06200	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BBF96_RS06205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BBF96_RS06210	COG0778	Nitroreductase
BBF96_RS06230	COG2302	S4 RNA-binding domain
BBF96_RS06235	COG0762	integral membrane protein
BBF96_RS06240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBF96_RS06250	COG1496	oxidoreductase activity
BBF96_RS06255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBF96_RS06260	COG1873	PFAM PRC-barrel domain
BBF96_RS06275	COG1191	sigma factor activity
BBF96_RS06280	COG1191	sigma factor activity
BBF96_RS06290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBF96_RS06305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBF96_RS06310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBF96_RS06315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BBF96_RS06320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBF96_RS06325	COG0772	Belongs to the SEDS family
BBF96_RS06330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBF96_RS06340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBF96_RS06345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBF96_RS06350	COG0768	penicillin binding
BBF96_RS06360	COG0275	rRNA processing
BBF96_RS06365	COG2001	Belongs to the MraZ family
BBF96_RS06380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBF96_RS06385	COG0393	Putative heavy-metal-binding
BBF96_RS06395	COG1181	Belongs to the D-alanine--D-alanine ligase family
BBF96_RS06410	COG0402	S-adenosylhomocysteine deaminase activity
BBF96_RS06530	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BBF96_RS06540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBF96_RS06565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBF96_RS06570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBF96_RS06605	COG1132	(ABC) transporter
BBF96_RS06610	COG1132	(ABC) transporter
BBF96_RS06615	COG1132	(ABC) transporter
BBF96_RS06640	COG0482	sulfurtransferase activity
BBF96_RS06645	COG0822	iron-sulfur transferase activity
BBF96_RS06655	COG1959	2 iron, 2 sulfur cluster binding
BBF96_RS06660	COG1739	Uncharacterized protein family UPF0029
BBF96_RS06665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BBF96_RS06670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBF96_RS06680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BBF96_RS06685	COG0124	histidyl-tRNA synthetase
BBF96_RS06690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBF96_RS06695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBF96_RS06700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBF96_RS06705	COG1490	D-aminoacyl-tRNA deacylase activity
BBF96_RS06710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBF96_RS06715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBF96_RS06720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BBF96_RS06720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBF96_RS06730	COG5416	Lipopolysaccharide assembly protein A domain
BBF96_RS06735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBF96_RS06740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBF96_RS06765	COG1131	(ABC) transporter
BBF96_RS06780	COG2197	response regulator
BBF96_RS06795	COG1862	Preprotein translocase
BBF96_RS06800	COG0343	queuine tRNA-ribosyltransferase activity
BBF96_RS06805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BBF96_RS06815	COG2255	four-way junction helicase activity
BBF96_RS06820	COG0632	four-way junction helicase activity
BBF96_RS06825	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BBF96_RS06835	COG0217	transcriptional regulatory protein
BBF96_RS06885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBF96_RS06895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBF96_RS06900	COG2313	pseudouridylate synthase activity
BBF96_RS06930	COG5002	protein histidine kinase activity
BBF96_RS06935	COG0745	RESPONSE REGULATOR receiver
BBF96_RS06950	COG0534	Mate efflux family protein
BBF96_RS06955	COG1937	Protein conserved in bacteria
BBF96_RS06970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBF96_RS06975	COG0358	DNA primase activity
BBF96_RS06980	COG1671	Belongs to the UPF0178 family
BBF96_RS06985	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BBF96_RS06990	COG0574	Belongs to the PEP-utilizing enzyme family
BBF96_RS06990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBF96_RS06995	COG1494	fructose-1,6-bisphosphatase
BBF96_RS07000	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBF96_RS07005	COG0517	IMP dehydrogenase activity
BBF96_RS07010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBF96_RS07020	COG1381	Involved in DNA repair and RecF pathway recombination
BBF96_RS07025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BBF96_RS07030	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBF96_RS07035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBF96_RS07040	COG0295	cytidine deaminase activity
BBF96_RS07045	COG1470	cell adhesion involved in biofilm formation
BBF96_RS07055	COG4536	flavin adenine dinucleotide binding
BBF96_RS07060	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BBF96_RS07070	COG1480	7TM receptor with intracellular HD hydrolase
BBF96_RS07075	COG1702	phosphate starvation-inducible protein PhoH
BBF96_RS07090	COG2323	membrane
BBF96_RS07095	COG2323	membrane
BBF96_RS07105	COG4864	UPF0365 protein
BBF96_RS07110	COG1030	water channel activity
BBF96_RS07120	COG1595	DNA-templated transcription, initiation
BBF96_RS07125	COG1610	YqeY-like protein
BBF96_RS07130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BBF96_RS07135	COG0537	adenosine 5'-monophosphoramidase activity
BBF96_RS07140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBF96_RS07145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBF96_RS07165	COG0484	heat shock protein binding
BBF96_RS07170	COG0443	Heat shock 70 kDa protein
BBF96_RS07175	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BBF96_RS07180	COG1420	regulation of RNA biosynthetic process
BBF96_RS07185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBF96_RS07205	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BBF96_RS07215	COG0268	Binds directly to 16S ribosomal RNA
BBF96_RS07220	COG1466	dna polymerase III delta subunit
BBF96_RS07230	COG0798	PFAM Bile acid sodium symporter
BBF96_RS07235	COG0640	Transcriptional regulator
BBF96_RS07260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBF96_RS07275	COG0352	thiamine-phosphate diphosphorylase activity
BBF96_RS07280	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BBF96_RS07285	COG0352	thiamine-phosphate diphosphorylase activity
BBF96_RS07290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BBF96_RS07295	COG2022	thiamine diphosphate biosynthetic process
BBF96_RS07305	COG2104	thiamine diphosphate biosynthetic process
BBF96_RS07305	COG2022	thiamine diphosphate biosynthetic process
BBF96_RS07315	COG0658	competence protein
BBF96_RS07315	COG2333	competence protein COMEC
BBF96_RS07325	COG0799	negative regulation of ribosome biogenesis
BBF96_RS07330	COG1316	TRANSCRIPTIONal
BBF96_RS07335	COG1713	HD superfamily hydrolase involved in NAD metabolism
BBF96_RS07340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBF96_RS07365	COG0697	spore germination
BBF96_RS07380	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BBF96_RS07425	COG1132	(ABC) transporter
BBF96_RS07430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBF96_RS07440	COG2855	membrane
BBF96_RS07445	COG0583	DNA-binding transcription factor activity
BBF96_RS07450	COG1405	negative regulation of cell septum assembly
BBF96_RS07450	COG3012	SEC-C Motif Domain Protein
BBF96_RS07485	COG2226	methyltransferase
BBF96_RS07490	COG2264	protein methyltransferase activity
BBF96_RS07510	COG1151	hydroxylamine reductase activity
BBF96_RS07575	COG0714	Associated with various cellular activities
BBF96_RS07580	COG0071	Belongs to the small heat shock protein (HSP20) family
BBF96_RS07600	COG0395	ABC-type sugar transport system, permease component
BBF96_RS07605	COG1175	transmembrane transport
BBF96_RS07625	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BBF96_RS07630	COG1609	Transcriptional regulator
BBF96_RS07640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBF96_RS07645	COG1473	amidohydrolase
BBF96_RS07665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBF96_RS07670	COG0785	Cytochrome C biogenesis protein
BBF96_RS07695	COG3033	Beta-eliminating lyase
BBF96_RS07700	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BBF96_RS07705	COG2362	D-Aminopeptidase
BBF96_RS07710	COG2814	Major facilitator Superfamily
BBF96_RS07725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBF96_RS07730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BBF96_RS07740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BBF96_RS07745	COG1530	ribonuclease E activity
BBF96_RS07770	COG0772	Belongs to the SEDS family
BBF96_RS07775	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BBF96_RS07780	COG2894	cell division
BBF96_RS07785	COG0850	regulation of cytokinetic process
BBF96_RS07790	COG0768	penicillin binding
BBF96_RS07800	COG1792	Involved in formation and maintenance of cell shape
BBF96_RS07805	COG1077	Cell shape determining protein MreB Mrl
BBF96_RS07810	COG2003	Belongs to the UPF0758 family
BBF96_RS07815	COG0424	maF-like protein
BBF96_RS07820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBF96_RS07825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BBF96_RS07835	COG0181	hydroxymethylbilane synthase activity
BBF96_RS07840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BBF96_RS07840	COG1648	precorrin-2 dehydrogenase activity
BBF96_RS07845	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BBF96_RS07855	COG2226	methyltransferase
BBF96_RS07860	COG2226	methyltransferase
BBF96_RS07865	COG2878	Part of a membrane complex involved in electron transport
BBF96_RS07865	COG1245	4Fe-4S binding domain
BBF96_RS07870	COG4657	Part of a membrane complex involved in electron transport
BBF96_RS07875	COG4660	Part of a membrane complex involved in electron transport
BBF96_RS07880	COG4659	FMN binding
BBF96_RS07885	COG4658	electron transport chain
BBF96_RS07890	COG4656	Part of a membrane complex involved in electron transport
BBF96_RS07900	COG0489	protein tyrosine kinase activity
BBF96_RS07905	COG2894	cell division
BBF96_RS07925	COG1342	Belongs to the UPF0251 family
BBF96_RS07930	COG5002	protein histidine kinase activity
BBF96_RS07945	COG0516	GMP reductase activity
BBF96_RS07945	COG0517	IMP dehydrogenase activity
BBF96_RS07960	COG0285	dihydrofolate synthase activity
BBF96_RS07965	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BBF96_RS07980	COG2198	Histidine kinase
BBF96_RS07980	COG0643	Histidine kinase
BBF96_RS07985	COG0745	RESPONSE REGULATOR receiver
BBF96_RS07990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BBF96_RS08000	COG2201	protein-glutamate methylesterase activity
BBF96_RS08005	COG0835	chemotaxis
BBF96_RS08015	COG3437	response regulator, receiver
BBF96_RS08025	COG0312	modulator of DNA gyrase
BBF96_RS08035	COG0251	oxidation-reduction process
BBF96_RS08040	COG0768	penicillin binding
BBF96_RS08045	COG4399	Belongs to the UPF0754 family
BBF96_RS08055	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BBF96_RS08055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBF96_RS08075	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBF96_RS08085	COG2226	methyltransferase
BBF96_RS08135	COG3328	transposase activity
BBF96_RS08170	COG0312	modulator of DNA gyrase
BBF96_RS08185	COG1032	radical SAM domain protein
BBF96_RS08210	COG0525	valine-tRNA ligase activity
BBF96_RS08225	COG0733	neurotransmitter:sodium symporter activity
BBF96_RS08240	COG1111	helicase
BBF96_RS08240	COG1205	dead DEAH box helicase
BBF96_RS08245	COG0583	DNA-binding transcription factor activity
BBF96_RS08270	COG0457	Tetratricopeptide repeat
BBF96_RS08270	COG0463	Glycosyl transferase, family 2
BBF96_RS08275	COG0463	Glycosyl transferase, family 2
BBF96_RS08280	COG0457	Tetratricopeptide repeat
BBF96_RS08280	COG0463	Glycosyl transferase, family 2
BBF96_RS08290	COG2226	methyltransferase
BBF96_RS08295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBF96_RS08325	COG3547	Transposase (IS116 IS110 IS902 family)
BBF96_RS08330	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BBF96_RS08335	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BBF96_RS08340	COG1067	ATP-dependent peptidase activity
BBF96_RS08340	COG0470	DNA polymerase III
BBF96_RS08345	COG0438	transferase activity, transferring glycosyl groups
BBF96_RS08355	COG1609	Transcriptional regulator
BBF96_RS08360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BBF96_RS08365	COG0740	serine-type endopeptidase activity
BBF96_RS08370	COG0544	peptidyl-prolyl cis-trans isomerase activity
BBF96_RS08385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BBF96_RS08390	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BBF96_RS08400	COG2894	cell division
BBF96_RS08415	COG4608	Belongs to the ABC transporter superfamily
BBF96_RS08420	COG0444	Belongs to the ABC transporter superfamily
BBF96_RS08430	COG0601	transmembrane transport
BBF96_RS08435	COG0747	negative chemotaxis
BBF96_RS08450	COG3799	methylaspartate ammonia-lyase activity
BBF96_RS08455	COG4865	methylaspartate mutase activity
BBF96_RS08465	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBF96_RS08470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BBF96_RS08475	COG1725	Transcriptional regulator
BBF96_RS08500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBF96_RS08525	COG0714	Associated with various cellular activities
BBF96_RS08535	COG1132	(ABC) transporter
BBF96_RS08545	COG0840	transmembrane signaling receptor activity
BBF96_RS08555	COG1027	Aspartate ammonia-lyase
BBF96_RS08560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBF96_RS08570	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BBF96_RS08575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBF96_RS08580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BBF96_RS08585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BBF96_RS08590	COG0302	gtp cyclohydrolase
BBF96_RS08595	COG1523	belongs to the glycosyl hydrolase 13 family
BBF96_RS08625	COG1592	Rubrerythrin
BBF96_RS08625	COG1773	rubredoxin
BBF96_RS08630	COG0840	transmembrane signaling receptor activity
BBF96_RS08630	COG5278	phosphoserine phosphatase activity
BBF96_RS08635	COG1686	Belongs to the peptidase S11 family
BBF96_RS08650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BBF96_RS08655	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BBF96_RS08665	COG0686	Belongs to the AlaDH PNT family
BBF96_RS08670	COG1300	Membrane
BBF96_RS08680	COG1379	DNA repair
BBF96_RS08695	COG2195	Cleaves the N-terminal amino acid of tripeptides
BBF96_RS08720	COG3426	butyrate kinase activity
BBF96_RS08730	COG0280	phosphate acetyltransferase
BBF96_RS08745	COG3829	transcription factor binding
BBF96_RS08745	COG3290	protein histidine kinase activity
BBF96_RS08750	COG0530	calcium, potassium:sodium antiporter activity
BBF96_RS08775	COG2746	aminoglycoside 3-N-acetyltransferase activity
BBF96_RS08780	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BBF96_RS08890	COG3547	Transposase (IS116 IS110 IS902 family)
BBF96_RS08900	COG3209	COG3209 Rhs family protein
BBF96_RS09030	COG3209	COG3209 Rhs family protein
BBF96_RS09080	COG1215	transferase activity, transferring glycosyl groups
BBF96_RS09095	COG0745	RESPONSE REGULATOR receiver
BBF96_RS09100	COG0750	zinc metalloprotease
BBF96_RS09105	COG0497	DNA recombination
BBF96_RS09110	COG1438	arginine binding
BBF96_RS09115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BBF96_RS09120	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BBF96_RS09125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBF96_RS09140	COG1722	exodeoxyribonuclease VII activity
BBF96_RS09145	COG1570	exodeoxyribonuclease VII activity
BBF96_RS09155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BBF96_RS09160	COG0493	'glutamate synthase
BBF96_RS09160	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BBF96_RS09190	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BBF96_RS09235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBF96_RS09255	COG1302	Protein conserved in bacteria
BBF96_RS09260	COG0439	Biotin carboxylase
BBF96_RS09265	COG0511	ligase activity, forming carbon-carbon bonds
BBF96_RS09310	COG3854	ATPases associated with a variety of cellular activities
BBF96_RS09315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BBF96_RS09320	COG1136	(ABC) transporter
BBF96_RS09330	COG1136	(ABC) transporter
BBF96_RS09330	COG0577	efflux transmembrane transporter activity
BBF96_RS09335	COG1136	(ABC) transporter
BBF96_RS09335	COG0577	efflux transmembrane transporter activity
BBF96_RS09350	COG0006	proline dipeptidase activity
BBF96_RS09355	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BBF96_RS09415	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BBF96_RS09420	COG2165	general secretion pathway protein
BBF96_RS09430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBF96_RS09445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BBF96_RS09480	COG0735	belongs to the Fur family
BBF96_RS09495	COG2002	toxin-antitoxin pair type II binding
BBF96_RS09520	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBF96_RS09530	COG0732	type I restriction modification DNA specificity domain
BBF96_RS09555	COG4555	ABC transporter
BBF96_RS09560	COG2252	PERMEase
BBF96_RS09565	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BBF96_RS09570	COG0167	dihydroorotate dehydrogenase activity
BBF96_RS09595	COG0402	S-adenosylhomocysteine deaminase activity
BBF96_RS09605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BBF96_RS09610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBF96_RS09615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBF96_RS09620	COG1396	sequence-specific DNA binding
BBF96_RS09625	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BBF96_RS09635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BBF96_RS09640	COG1228	amidohydrolase
BBF96_RS09655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BBF96_RS09675	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BBF96_RS09685	COG0826	peptidase U32
BBF96_RS09690	COG4122	O-methyltransferase activity
BBF96_RS09695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BBF96_RS09705	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BBF96_RS09740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BBF96_RS09745	COG0628	permease
BBF96_RS09770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BBF96_RS09785	COG0330	HflC and HflK could
BBF96_RS09790	COG0330	HflC and HflK could
BBF96_RS09795	COG0495	leucyl-tRNA aminoacylation
BBF96_RS09805	COG2226	methyltransferase
BBF96_RS09810	COG0328	RNA-DNA hybrid ribonuclease activity
BBF96_RS09830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBF96_RS09855	COG1523	belongs to the glycosyl hydrolase 13 family
BBF96_RS09870	COG0849	cell division
BBF96_RS09885	COG0667	Aldo Keto reductase
BBF96_RS09890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBF96_RS09925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BBF96_RS09930	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BBF96_RS09940	COG1193	negative regulation of DNA recombination
BBF96_RS09945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBF96_RS09945	COG1796	DNA polymerase
BBF96_RS09960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBF96_RS09985	COG0072	phenylalanine-tRNA ligase activity
BBF96_RS09985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBF96_RS09990	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BBF96_RS10000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBF96_RS10005	COG0569	domain protein
BBF96_RS10010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBF96_RS10015	COG0569	domain protein
BBF96_RS10020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBF96_RS10025	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BBF96_RS10030	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BBF96_RS10035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBF96_RS10045	COG1132	(ABC) transporter
BBF96_RS10050	COG1132	(ABC) transporter
BBF96_RS10055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BBF96_RS10060	COG4399	Belongs to the UPF0754 family
BBF96_RS10075	COG0658	competence protein
BBF96_RS10075	COG2333	competence protein COMEC
BBF96_RS10140	COG4608	Belongs to the ABC transporter superfamily
BBF96_RS10145	COG0444	Belongs to the ABC transporter superfamily
BBF96_RS10150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_RS10155	COG0601	transmembrane transport
BBF96_RS10180	COG4608	Belongs to the ABC transporter superfamily
BBF96_RS10185	COG0444	Belongs to the ABC transporter superfamily
BBF96_RS10190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_RS10195	COG0601	transmembrane transport
BBF96_RS10200	COG0747	negative chemotaxis
BBF96_RS10210	COG0312	modulator of DNA gyrase
BBF96_RS10215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBF96_RS10220	COG0641	radical SAM
BBF96_RS10225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBF96_RS10235	COG1132	(ABC) transporter
BBF96_RS10240	COG1132	(ABC) transporter
BBF96_RS10245	COG4608	Belongs to the ABC transporter superfamily
BBF96_RS10250	COG0444	Belongs to the ABC transporter superfamily
BBF96_RS10255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_RS10260	COG0601	transmembrane transport
BBF96_RS10265	COG0747	negative chemotaxis
BBF96_RS10270	COG1966	Carbon starvation protein
BBF96_RS10275	COG0741	lytic transglycosylase activity
BBF96_RS10275	COG0739	heme binding
BBF96_RS10275	COG1196	nuclear chromosome segregation
BBF96_RS10285	COG0237	dephospho-CoA kinase activity
BBF96_RS10290	COG1971	Probably functions as a manganese efflux pump
BBF96_RS10295	COG0488	(ABC) transporter
BBF96_RS10300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BBF96_RS10340	COG0312	modulator of DNA gyrase
BBF96_RS10345	COG0312	modulator of DNA gyrase
BBF96_RS10370	COG0312	modulator of DNA gyrase
BBF96_RS10380	COG4555	ABC transporter
BBF96_RS10385	COG1032	radical SAM domain protein
BBF96_RS10415	COG0535	radical SAM domain protein
BBF96_RS10435	COG4555	ABC transporter
BBF96_RS10445	COG1879	ABC-type sugar transport system periplasmic component
BBF96_RS10450	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBF96_RS10460	COG1869	D-ribose catabolic process
BBF96_RS10465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBF96_RS10475	COG1301	dicarboxylic acid transport
BBF96_RS10485	COG1785	Belongs to the alkaline phosphatase family
BBF96_RS10520	COG0395	ABC-type sugar transport system, permease component
BBF96_RS10530	COG2182	Extracellular solute-binding protein
BBF96_RS10540	COG3459	Glycosyltransferase 36 associated
BBF96_RS10545	COG1609	Transcriptional regulator
BBF96_RS10550	COG2723	6-phospho-beta-galactosidase activity
BBF96_RS10585	COG2176	DNA-directed DNA polymerase activity
BBF96_RS10595	COG1840	ABC-type Fe3 transport system, periplasmic component
BBF96_RS10600	COG1178	ABC-type Fe3 transport system permease component
BBF96_RS10605	COG3842	ATPase activity
BBF96_RS10610	COG3290	protein histidine kinase activity
BBF96_RS10610	COG0840	transmembrane signaling receptor activity
BBF96_RS10670	COG1595	DNA-templated transcription, initiation
BBF96_RS10675	COG2911	Protein conserved in bacteria
BBF96_RS10675	COG1361	Conserved repeat domain
BBF96_RS10675	COG3266	domain, Protein
BBF96_RS10680	COG1376	ErfK ybiS ycfS ynhG family protein
BBF96_RS10735	COG1473	amidohydrolase
BBF96_RS10740	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BBF96_RS10755	COG0395	ABC-type sugar transport system, permease component
BBF96_RS10760	COG1175	transmembrane transport
BBF96_RS10765	COG1653	transport
BBF96_RS10770	COG1609	Transcriptional regulator
BBF96_RS10775	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BBF96_RS10785	COG3679	Belongs to the UPF0342 family
BBF96_RS10795	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BBF96_RS10810	COG0010	Belongs to the arginase family
BBF96_RS10815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BBF96_RS10825	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BBF96_RS10845	COG2959	enzyme of heme biosynthesis
BBF96_RS10865	COG1683	Conserved Protein
BBF96_RS10880	COG1959	2 iron, 2 sulfur cluster binding
BBF96_RS10885	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BBF96_RS10890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BBF96_RS10905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BBF96_RS10910	COG1132	(ABC) transporter
BBF96_RS10925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBF96_RS10930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BBF96_RS10935	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BBF96_RS10945	COG1846	Transcriptional regulator
BBF96_RS10955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBF96_RS11000	COG1706	bacterial-type flagellum-dependent cell motility
BBF96_RS11005	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BBF96_RS11020	COG4786	Flagellar basal body rod
BBF96_RS11045	COG1191	sigma factor activity
BBF96_RS11065	COG1419	protein localization to endoplasmic reticulum
BBF96_RS11070	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBF96_RS11075	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBF96_RS11080	COG1684	flagellar biosynthetic protein fliR
BBF96_RS11085	COG1987	bacterial-type flagellum assembly
BBF96_RS11090	COG1338	Plays a role in the flagellum-specific transport system
BBF96_RS11100	COG1776	CheC inhibitor of MCP methylation
BBF96_RS11100	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBF96_RS11105	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBF96_RS11115	COG1360	Flagellar Motor Protein
BBF96_RS11125	COG1582	Flagellar protein (FlbD)
BBF96_RS11140	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BBF96_RS11155	COG2882	bacterial-type flagellum organization
BBF96_RS11160	COG1157	protein secretion by the type III secretion system
BBF96_RS11165	COG1317	bacterial-type flagellum organization
BBF96_RS11170	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBF96_RS11175	COG1766	The M ring may be actively involved in energy transduction
BBF96_RS11180	COG1677	Flagellar hook-basal body complex protein FliE
BBF96_RS11190	COG1815	bacterial-type flagellum-dependent cell motility
BBF96_RS11195	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BBF96_RS11205	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBF96_RS11210	COG2089	acid synthase
BBF96_RS11215	COG1083	cytidylyl-transferase
BBF96_RS11220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BBF96_RS11225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BBF96_RS11235	COG1516	flagellar protein fliS
BBF96_RS11255	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BBF96_RS11260	COG1334	flagellar protein FlaG
BBF96_RS11265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBF96_RS11270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BBF96_RS11275	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BBF96_RS11285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBF96_RS11290	COG4786	Flagellar basal body rod
BBF96_RS11290	COG1256	bacterial-type flagellum assembly
BBF96_RS11310	COG0572	uridine kinase
BBF96_RS11330	COG1404	Belongs to the peptidase S8 family
BBF96_RS11340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBF96_RS11345	COG1482	cell wall glycoprotein biosynthetic process
BBF96_RS11370	COG0166	Belongs to the GPI family
BBF96_RS11375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBF96_RS11395	COG0728	peptidoglycan biosynthetic process
BBF96_RS11400	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BBF96_RS11405	COG3475	LICD family
BBF96_RS11420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBF96_RS11445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BBF96_RS11480	COG3206	protein involved in exopolysaccharide biosynthesis
BBF96_RS11490	COG4372	Transposase
BBF96_RS11500	COG1137	ATPase activity
BBF96_RS11515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BBF96_RS11525	COG1132	(ABC) transporter
BBF96_RS11530	COG1216	Glycosyl transferase, family 2
BBF96_RS11540	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBF96_RS11545	COG3494	Protein of unknown function (DUF1009)
BBF96_RS11550	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBF96_RS11555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BBF96_RS11615	COG3328	transposase activity
BBF96_RS11625	COG3328	transposase activity
BBF96_RS11630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBF96_RS11650	COG1404	Belongs to the peptidase S8 family
BBF96_RS11670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBF96_RS11710	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BBF96_RS11715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBF96_RS11730	COG1077	Cell shape determining protein MreB Mrl
BBF96_RS11735	COG1609	Transcriptional regulator
BBF96_RS11745	COG2385	sporulation resulting in formation of a cellular spore
BBF96_RS11750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBF96_RS11790	COG0840	transmembrane signaling receptor activity
BBF96_RS11795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BBF96_RS11800	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BBF96_RS11805	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BBF96_RS11810	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BBF96_RS11815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBF96_RS11820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BBF96_RS11830	COG0356	it plays a direct role in the translocation of protons across the membrane
BBF96_RS11850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBF96_RS11865	COG0698	ribose 5-phosphate isomerase
BBF96_RS11870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBF96_RS11875	COG1971	Probably functions as a manganese efflux pump
BBF96_RS11880	COG0009	L-threonylcarbamoyladenylate synthase
BBF96_RS11890	COG2890	protein-(glutamine-N5) methyltransferase activity
BBF96_RS11895	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BBF96_RS11900	COG3872	metal-dependent enzyme
BBF96_RS11905	COG1435	thymidine kinase activity
BBF96_RS11910	COG0840	transmembrane signaling receptor activity
BBF96_RS11915	COG0254	rRNA binding
BBF96_RS11920	COG0739	heme binding
BBF96_RS11925	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BBF96_RS11960	COG0140	phosphoribosyl-ATP diphosphatase activity
BBF96_RS11960	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BBF96_RS11965	COG0107	imidazoleglycerol-phosphate synthase activity
BBF96_RS11970	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BBF96_RS11975	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BBF96_RS11980	COG0131	Imidazoleglycerol-phosphate dehydratase
BBF96_RS11985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBF96_RS11995	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BBF96_RS12000	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BBF96_RS12005	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBF96_RS12040	COG0840	transmembrane signaling receptor activity
BBF96_RS12085	COG0504	CTP synthase activity
BBF96_RS12115	COG3706	GGDEF domain
BBF96_RS12120	COG1024	Enoyl-CoA hydratase
BBF96_RS12125	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBF96_RS12130	COG0183	Belongs to the thiolase family
BBF96_RS12140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BBF96_RS12145	COG3246	L-lysine catabolic process to acetate
BBF96_RS12150	COG1607	acyl-coa hydrolase
BBF96_RS12160	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBF96_RS12165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBF96_RS12170	COG1193	negative regulation of DNA recombination
BBF96_RS12180	COG0604	alcohol dehydrogenase
BBF96_RS12235	COG1136	(ABC) transporter
BBF96_RS12235	COG0577	efflux transmembrane transporter activity
BBF96_RS12240	COG5002	protein histidine kinase activity
BBF96_RS12245	COG0745	RESPONSE REGULATOR receiver
BBF96_RS12260	COG1136	(ABC) transporter
BBF96_RS12260	COG0577	efflux transmembrane transporter activity
BBF96_RS12265	COG1136	(ABC) transporter
BBF96_RS12465	COG3290	protein histidine kinase activity
BBF96_RS12465	COG3829	transcription factor binding
BBF96_RS12475	COG2059	Chromate
BBF96_RS12505	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BBF96_RS12510	COG0076	glutamate decarboxylase activity
BBF96_RS12515	COG0667	Aldo Keto reductase
BBF96_RS12525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BBF96_RS12530	COG2002	toxin-antitoxin pair type II binding
BBF96_RS12545	COG1744	ABC transporter substrate-binding protein PnrA-like
BBF96_RS12560	COG0697	spore germination
BBF96_RS12575	COG3546	catalase activity
BBF96_RS12590	COG1966	Carbon starvation protein
BBF96_RS12600	COG3275	phosphorelay sensor kinase activity
BBF96_RS12615	COG0531	amino acid
BBF96_RS12620	COG0697	spore germination
BBF96_RS12635	COG1454	alcohol dehydrogenase
BBF96_RS12650	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BBF96_RS12655	COG5609	conserved protein (DUF2294)
BBF96_RS12665	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BBF96_RS12670	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BBF96_RS12680	COG1454	alcohol dehydrogenase
BBF96_RS12710	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BBF96_RS12715	COG1966	Carbon starvation protein
BBF96_RS12720	COG1966	Carbon starvation protein
BBF96_RS12735	COG1592	Rubrerythrin
BBF96_RS12740	COG3706	GGDEF domain
BBF96_RS12745	COG2244	polysaccharide biosynthetic process
BBF96_RS12760	COG0626	cystathionine gamma-synthase activity
BBF96_RS12765	COG1988	membrane-bound metal-dependent
BBF96_RS12775	COG1691	(AIR) carboxylase
BBF96_RS12780	COG1606	tRNA processing
BBF96_RS12795	COG0189	ligase activity
BBF96_RS12825	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BBF96_RS12830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BBF96_RS12835	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BBF96_RS12840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBF96_RS12845	COG1605	Chorismate mutase
BBF96_RS12845	COG0077	Prephenate dehydratase
BBF96_RS12850	COG0287	Prephenate dehydrogenase
BBF96_RS12855	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBF96_RS12860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBF96_RS12865	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BBF96_RS12870	COG0018	arginyl-trna synthetase
BBF96_RS12895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBF96_RS12910	COG3706	GGDEF domain
BBF96_RS12915	COG5002	protein histidine kinase activity
BBF96_RS12930	COG1404	Belongs to the peptidase S8 family
BBF96_RS12945	COG0697	spore germination
BBF96_RS12970	COG2226	methyltransferase
BBF96_RS12990	COG1131	(ABC) transporter
BBF96_RS13045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BBF96_RS13055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBF96_RS13060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BBF96_RS13065	COG2201	protein-glutamate methylesterase activity
BBF96_RS13070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BBF96_RS13080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBF96_RS13085	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BBF96_RS13095	COG1266	CAAX protease self-immunity
BBF96_RS13100	COG5002	protein histidine kinase activity
BBF96_RS13105	COG0745	RESPONSE REGULATOR receiver
BBF96_RS13120	COG0138	bifunctional purine biosynthesis protein purh
BBF96_RS13125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBF96_RS13130	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BBF96_RS13135	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BBF96_RS13140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBF96_RS13145	COG0047	phosphoribosylformylglycinamidine synthase activity
BBF96_RS13150	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBF96_RS13155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BBF96_RS13160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBF96_RS13215	COG0584	glycerophosphoryl diester phosphodiesterase
BBF96_RS13225	COG1752	Esterase of the alpha-beta hydrolase superfamily
BBF96_RS13230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBF96_RS13235	COG0151	Belongs to the GarS family
BBF96_RS13240	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BBF96_RS13245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBF96_RS13250	COG1605	Chorismate mutase
BBF96_RS13250	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBF96_RS13275	COG1032	radical SAM domain protein
BBF96_RS13305	COG1484	DNA-dependent DNA replication
BBF96_RS13310	COG0305	Participates in initiation and elongation during chromosome replication
BBF96_RS13325	COG1067	ATP-dependent peptidase activity
BBF96_RS13325	COG0470	DNA polymerase III
BBF96_RS13330	COG0359	binds to the 23S rRNA
BBF96_RS13345	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BBF96_RS13350	COG0629	single-stranded DNA binding
BBF96_RS13355	COG0360	Binds together with S18 to 16S ribosomal RNA
BBF96_RS13365	COG4555	ABC transporter
BBF96_RS13380	COG0012	GTP binding
BBF96_RS13385	COG4481	Protein conserved in bacteria
BBF96_RS13390	COG0668	transmembrane transport
BBF96_RS13420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBF96_RS13425	COG3949	Membrane
BBF96_RS13440	COG1597	lipid kinase activity
BBF96_RS13450	COG0739	heme binding
BBF96_RS13475	COG0569	domain protein
BBF96_RS13480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBF96_RS13485	COG1475	DNA binding
BBF96_RS13490	COG1192	Involved in chromosome partitioning
BBF96_RS13500	COG0357	Ribosomal RNA small subunit methyltransferase G
BBF96_RS13505	COG0445	tRNA wobble uridine modification
BBF96_RS13510	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBF96_RS13515	COG1847	R3H domain protein
BBF96_RS13520	COG0706	membrane insertase activity
BBF96_RS13525	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BBF96_RS13535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BBF96_RS13540	COG0592	DNA-directed DNA polymerase activity
BBF96_RS13550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BBF96_RS13560	COG0187	DNA topoisomerase II activity
BBF96_RS13565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBF96_RS13665	COG2814	Major facilitator Superfamily
BBF96_RS13710	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBF96_RS13745	COG5012	cobalamin binding
BBF96_RS13765	COG0604	alcohol dehydrogenase
BBF96_RS13770	COG0647	UMP catabolic process
BBF96_RS13775	COG0165	Argininosuccinate lyase
BBF96_RS13785	COG3829	transcription factor binding
BBF96_RS13790	COG0616	signal peptide processing
BBF96_RS13800	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BBF96_RS13820	COG0420	3'-5' exonuclease activity
BBF96_RS13830	COG3852	Histidine kinase
BBF96_RS13835	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBF96_RS13850	COG0590	tRNA wobble adenosine to inosine editing
BBF96_RS13860	COG1051	belongs to the nudix hydrolase family
BBF96_RS13905	COG4555	ABC transporter
BBF96_RS13950	COG3339	Conserved Protein
BBF96_RS13955	COG2226	methyltransferase
BBF96_RS14025	COG0514	ATP-dependent DNA helicase (RecQ)
BBF96_RS14030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBF96_RS14060	COG4555	ABC transporter
BBF96_RS14065	COG1342	Belongs to the UPF0251 family
BBF96_RS14085	COG1131	(ABC) transporter
BBF96_RS14090	COG0535	radical SAM domain protein
BBF96_RS14095	COG0488	(ABC) transporter
BBF96_RS14105	COG1132	(ABC) transporter
BBF96_RS14115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBF96_RS14120	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BBF96_RS14125	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BBF96_RS14140	COG1809	phosphosulfolactate synthase activity
BBF96_RS14145	COG2045	Belongs to the ComB family
BBF96_RS14150	COG2707	UPF0756 membrane protein
BBF96_RS14165	COG2855	membrane
BBF96_RS14170	COG0840	transmembrane signaling receptor activity
BBF96_RS14200	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BBF96_RS14205	COG1144	Oxidoreductase
BBF96_RS14210	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBF96_RS14215	COG1013	pyruvate-flavodoxin oxidoreductase activity
BBF96_RS14230	COG3290	protein histidine kinase activity
BBF96_RS14230	COG0840	transmembrane signaling receptor activity
BBF96_RS14240	COG0516	GMP reductase activity
BBF96_RS14240	COG0517	IMP dehydrogenase activity
BBF96_RS14245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBF96_RS14255	COG3870	Protein conserved in bacteria
BBF96_RS14260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBF96_RS14265	COG1774	PSP1 C-terminal conserved region
BBF96_RS14275	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BBF96_RS14280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BBF96_RS14285	COG2002	toxin-antitoxin pair type II binding
BBF96_RS14290	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBF96_RS14290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBF96_RS14310	COG0084	hydrolase, TatD family'
BBF96_RS14325	COG4585	Histidine kinase
BBF96_RS14330	COG2197	response regulator
BBF96_RS14355	COG3858	chitin binding
BBF96_RS14365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBF96_RS14395	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BBF96_RS14410	COG4466	Protein conserved in bacteria
BBF96_RS14430	COG1215	transferase activity, transferring glycosyl groups
BBF96_RS14445	COG0745	RESPONSE REGULATOR receiver
BBF96_RS14450	COG5002	protein histidine kinase activity
BBF96_RS14455	COG0037	tRNA processing
BBF96_RS14465	COG0561	phosphatase activity
BBF96_RS14480	COG1175	transmembrane transport
BBF96_RS14485	COG0395	ABC-type sugar transport system, permease component
BBF96_RS14490	COG1554	hydrolase, family 65, central catalytic
BBF96_RS14525	COG0535	radical SAM domain protein
BBF96_RS14530	COG4152	abc transporter atp-binding protein
BBF96_RS14540	COG0312	modulator of DNA gyrase
BBF96_RS14560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BBF96_RS14565	COG0573	inorganic phosphate transmembrane transporter activity
BBF96_RS14575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBF96_RS14580	COG0704	Plays a role in the regulation of phosphate uptake
BBF96_RS14585	COG0747	negative chemotaxis
BBF96_RS14590	COG0601	transmembrane transport
BBF96_RS14595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_RS14615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBF96_RS14620	COG3181	Tripartite tricarboxylate transporter family receptor
BBF96_RS14635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBF96_RS14640	COG1414	Transcriptional regulator
BBF96_RS14675	COG0601	transmembrane transport
BBF96_RS14680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_RS14685	COG0038	chloride channel
BBF96_RS14690	COG1980	fructose-bisphosphate aldolase activity
BBF96_RS14695	COG0017	Asparaginyl-tRNA synthetase
BBF96_RS14705	COG0301	tRNA thio-modification
BBF96_RS14710	COG3290	protein histidine kinase activity
BBF96_RS14710	COG0840	transmembrane signaling receptor activity
BBF96_RS14730	COG0840	transmembrane signaling receptor activity
BBF96_RS14730	COG3290	protein histidine kinase activity
BBF96_RS14740	COG1376	ErfK ybiS ycfS ynhG family protein
BBF96_RS14745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBF96_RS14755	COG1459	type II secretion system
BBF96_RS14760	COG4968	Prepilin-type N-terminal cleavage methylation domain
BBF96_RS14825	COG2340	Cysteine-rich secretory protein family
BBF96_RS14845	COG2226	methyltransferase
BBF96_RS14850	COG0626	cystathionine gamma-synthase activity
BBF96_RS14855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBF96_RS14890	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BBF96_RS14900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBF96_RS14920	COG1131	(ABC) transporter
BBF96_RS14955	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BBF96_RS14970	COG0039	L-malate dehydrogenase activity
BBF96_RS14995	COG3328	transposase activity
BBF96_RS15045	COG1797	cobyrinic acid a,c-diamide synthase activity
BBF96_RS15050	COG1492	cobalamin metabolic process
BBF96_RS15055	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BBF96_RS15060	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BBF96_RS15085	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BBF96_RS15095	COG0789	Transcriptional regulator
BBF96_RS15100	COG0174	glutamine synthetase
BBF96_RS15110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBF96_RS15125	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBF96_RS15130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBF96_RS15135	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BBF96_RS15140	COG0193	aminoacyl-tRNA hydrolase activity
BBF96_RS15150	COG1842	Phage shock protein A
BBF96_RS15170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BBF96_RS15185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBF96_RS15190	COG2002	toxin-antitoxin pair type II binding
BBF96_RS15195	COG2244	polysaccharide biosynthetic process
BBF96_RS15200	COG3956	TIGRFAM MazG family protein
BBF96_RS15210	COG1686	Belongs to the peptidase S11 family
BBF96_RS15215	COG2385	sporulation resulting in formation of a cellular spore
BBF96_RS15310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBF96_RS15315	COG1120	ATPase activity
BBF96_RS15335	COG3608	succinylglutamate desuccinylase aspartoacylase
BBF96_RS15335	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BBF96_RS15345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBF96_RS15350	COG2068	MobA-Related Protein
BBF96_RS15355	COG3608	succinylglutamate desuccinylase aspartoacylase
BBF96_RS15355	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BBF96_RS15375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBF96_RS15380	COG0549	Belongs to the carbamate kinase family
BBF96_RS15390	COG3842	ATPase activity
BBF96_RS15405	COG3706	GGDEF domain
BBF96_RS15430	COG2183	response to ionizing radiation
BBF96_RS15445	COG1131	(ABC) transporter
BBF96_RS15450	COG2208	phosphoserine phosphatase activity
BBF96_RS15455	COG0037	tRNA processing
BBF96_RS15460	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BBF96_RS15465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBF96_RS15475	COG2986	histidine ammonia-lyase
BBF96_RS15480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BBF96_RS15490	COG1228	amidohydrolase
BBF96_RS15495	COG3404	Formiminotransferase-cyclodeaminase
BBF96_RS15500	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BBF96_RS15505	COG0432	Pfam Uncharacterised protein family UPF0047
BBF96_RS15525	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BBF96_RS15530	COG1027	Aspartate ammonia-lyase
BBF96_RS15550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BBF96_RS15555	COG0825	malonyl-CoA metabolic process
BBF96_RS15560	COG0205	6-phosphofructokinase activity
BBF96_RS15570	COG3030	protein affecting phage T7 exclusion by the F plasmid
BBF96_RS15590	COG0739	heme binding
BBF96_RS15590	COG1196	nuclear chromosome segregation
BBF96_RS15590	COG0741	lytic transglycosylase activity
BBF96_RS15595	COG0640	Transcriptional regulator
BBF96_RS15600	COG3290	protein histidine kinase activity
BBF96_RS15600	COG3829	transcription factor binding
BBF96_RS15605	COG4656	Part of a membrane complex involved in electron transport
BBF96_RS15610	COG0252	asparaginase activity
BBF96_RS15610	COG5275	peptidyl-tyrosine sulfation
BBF96_RS15625	COG5275	peptidyl-tyrosine sulfation
BBF96_RS15625	COG0252	asparaginase activity
BBF96_RS15630	COG0252	asparaginase activity
BBF96_RS15630	COG5275	peptidyl-tyrosine sulfation
BBF96_RS15655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BBF96_RS15670	COG1131	(ABC) transporter
BBF96_RS15685	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BBF96_RS15690	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BBF96_RS15695	COG0406	alpha-ribazole phosphatase activity
BBF96_RS15700	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BBF96_RS15710	COG0745	RESPONSE REGULATOR receiver
BBF96_RS15715	COG5002	protein histidine kinase activity
BBF96_RS15720	COG2239	Acts as a magnesium transporter
BBF96_RS15730	COG0019	diaminopimelate decarboxylase activity
BBF96_RS15735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BBF96_RS15755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BBF96_RS15760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BBF96_RS15765	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BBF96_RS15770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BBF96_RS15775	COG0157	Belongs to the NadC ModD family
BBF96_RS15825	COG1268	BioY protein
BBF96_RS15830	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BBF96_RS15860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBF96_RS15860	COG5322	oxidoreductase activity
BBF96_RS15865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBF96_RS15870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BBF96_RS15895	COG4555	ABC transporter
BBF96_RS15925	COG3880	PFAM UvrB UvrC protein
BBF96_RS15930	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BBF96_RS15935	COG0542	response to heat
BBF96_RS15940	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BBF96_RS15945	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BBF96_RS15955	COG1329	Transcriptional regulator
BBF96_RS15960	COG4956	integral membrane protein (PIN domain superfamily)
BBF96_RS15965	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BBF96_RS15970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BBF96_RS15985	COG1757	Na H antiporter
BBF96_RS15995	COG4086	secreted protein
BBF96_RS16000	COG1045	serine acetyltransferase
BBF96_RS16005	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BBF96_RS16015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBF96_RS16025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBF96_RS16030	COG2813	Specifically methylates the guanine in position
BBF96_RS16035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BBF96_RS16040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBF96_RS16045	COG0250	Participates in transcription elongation, termination and antitermination
BBF96_RS16050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BBF96_RS16055	COG0081	regulation of translation
BBF96_RS16060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BBF96_RS16065	COG0222	ribosome binding
BBF96_RS16070	COG0085	RNA polymerase activity
BBF96_RS16075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBF96_RS16080	COG1358	cellular component organization or biogenesis
BBF96_RS16085	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BBF96_RS16090	COG0049	tRNA binding
BBF96_RS16095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBF96_RS16100	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBF96_RS16105	COG0051	transcription antitermination factor activity, RNA binding
BBF96_RS16110	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BBF96_RS16115	COG0088	Forms part of the polypeptide exit tunnel
BBF96_RS16120	COG0089	rRNA binding
BBF96_RS16125	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBF96_RS16130	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BBF96_RS16135	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BBF96_RS16140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BBF96_RS16145	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BBF96_RS16150	COG0255	Belongs to the universal ribosomal protein uL29 family
BBF96_RS16155	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BBF96_RS16160	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BBF96_RS16165	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BBF96_RS16170	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBF96_RS16175	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BBF96_RS16180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BBF96_RS16185	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BBF96_RS16190	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BBF96_RS16195	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BBF96_RS16200	COG0200	Binds to the 23S rRNA
BBF96_RS16210	COG0563	adenylate kinase activity
BBF96_RS16225	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBF96_RS16230	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BBF96_RS16235	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBF96_RS16240	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BBF96_RS16245	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BBF96_RS16250	COG0202	RNA polymerase activity
BBF96_RS16255	COG0203	ribosomal protein L17
BBF96_RS16260	COG1122	ATPase activity
BBF96_RS16270	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBF96_RS16275	COG0101	tRNA pseudouridine synthase activity
BBF96_RS16280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBF96_RS16285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)