locus-tag	class	description
ANTHELSMS3_RS00015	COG3386	PFAM SMP-30 Gluconolaconase
ANTHELSMS3_RS00020	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS00075	COG0493	'glutamate synthase
ANTHELSMS3_RS00090	COG1309	transcriptional regulator
ANTHELSMS3_RS00115	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ANTHELSMS3_RS00125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_RS00130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_RS00160	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ANTHELSMS3_RS00185	COG3453	Protein conserved in bacteria
ANTHELSMS3_RS00185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANTHELSMS3_RS00200	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS00205	COG3769	mannosylglycerate metabolic process
ANTHELSMS3_RS00210	COG1072	(Pantothenic acid kinase))
ANTHELSMS3_RS00215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ANTHELSMS3_RS00230	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ANTHELSMS3_RS00240	COG0628	permease
ANTHELSMS3_RS00270	COG3920	Histidine kinase
ANTHELSMS3_RS00295	COG3237	CsbD-like
ANTHELSMS3_RS00300	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ANTHELSMS3_RS00320	COG0784	Response regulator, receiver
ANTHELSMS3_RS00335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANTHELSMS3_RS00340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANTHELSMS3_RS00340	COG1321	iron dependent repressor
ANTHELSMS3_RS00345	COG1121	(ABC) transporter
ANTHELSMS3_RS00350	COG0803	Belongs to the bacterial solute-binding protein 9 family
ANTHELSMS3_RS00355	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ANTHELSMS3_RS00370	COG0736	holo-[acyl-carrier-protein] synthase activity
ANTHELSMS3_RS00390	COG0681	Belongs to the peptidase S26 family
ANTHELSMS3_RS00400	COG0571	ribonuclease III activity
ANTHELSMS3_RS00410	COG0697	spore germination
ANTHELSMS3_RS00415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ANTHELSMS3_RS00425	COG1381	Involved in DNA repair and RecF pathway recombination
ANTHELSMS3_RS00435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ANTHELSMS3_RS00445	COG0314	molybdopterin synthase activity
ANTHELSMS3_RS00455	COG0004	ammonium transporteR
ANTHELSMS3_RS00460	COG0347	Belongs to the P(II) protein family
ANTHELSMS3_RS00465	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ANTHELSMS3_RS00480	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
ANTHELSMS3_RS00485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANTHELSMS3_RS00505	COG0495	leucyl-tRNA aminoacylation
ANTHELSMS3_RS00510	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS00525	COG0457	Tetratricopeptide repeat
ANTHELSMS3_RS00530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ANTHELSMS3_RS00535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANTHELSMS3_RS00540	COG0196	riboflavin kinase activity
ANTHELSMS3_RS00545	COG2983	Belongs to the UPF0260 family
ANTHELSMS3_RS00570	COG3932	Exopolysaccharide synthesis, ExoD
ANTHELSMS3_RS00575	COG1674	ftsk spoiiie
ANTHELSMS3_RS00580	COG0436	Aminotransferase
ANTHELSMS3_RS00590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ANTHELSMS3_RS00595	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS00655	COG0435	Glutathione S-transferase
ANTHELSMS3_RS00675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ANTHELSMS3_RS00680	COG0242	peptide deformylase activity
ANTHELSMS3_RS00685	COG0242	peptide deformylase activity
ANTHELSMS3_RS00690	COG0242	peptide deformylase activity
ANTHELSMS3_RS00695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ANTHELSMS3_RS00700	COG2860	membrane
ANTHELSMS3_RS00705	COG0328	RNA-DNA hybrid ribonuclease activity
ANTHELSMS3_RS00715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ANTHELSMS3_RS00725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ANTHELSMS3_RS00730	COG1758	RNA polymerase activity
ANTHELSMS3_RS00760	COG2154	pterin-4-alpha-carbinolamine dehydratase
ANTHELSMS3_RS00765	COG0678	peroxiredoxin activity
ANTHELSMS3_RS00775	COG0742	ribosomal rna small subunit methyltransferase
ANTHELSMS3_RS00790	COG0517	IMP dehydrogenase activity
ANTHELSMS3_RS00790	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ANTHELSMS3_RS00790	COG0617	tRNA 3'-terminal CCA addition
ANTHELSMS3_RS00795	COG0024	Methionine aminopeptidase
ANTHELSMS3_RS00840	COG1194	a g-specific adenine glycosylase
ANTHELSMS3_RS00845	COG3239	Fatty acid desaturase
ANTHELSMS3_RS00855	COG1489	DNA binding
ANTHELSMS3_RS00860	COG1546	Belongs to the CinA family
ANTHELSMS3_RS00860	COG1058	Belongs to the CinA family
ANTHELSMS3_RS00880	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS00890	COG0693	protein deglycase activity
ANTHELSMS3_RS00895	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_RS00895	COG1902	pentaerythritol trinitrate reductase activity
ANTHELSMS3_RS00915	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_RS00920	COG0799	negative regulation of ribosome biogenesis
ANTHELSMS3_RS00925	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ANTHELSMS3_RS00930	COG1968	undecaprenyl-diphosphatase activity
ANTHELSMS3_RS00955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANTHELSMS3_RS00965	COG1459	type II secretion system
ANTHELSMS3_RS00970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ANTHELSMS3_RS01005	COG0697	spore germination
ANTHELSMS3_RS01010	COG1131	(ABC) transporter
ANTHELSMS3_RS01015	COG0842	Transport permease protein
ANTHELSMS3_RS01055	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ANTHELSMS3_RS01095	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ANTHELSMS3_RS01110	COG2226	methyltransferase
ANTHELSMS3_RS01115	COG0039	L-malate dehydrogenase activity
ANTHELSMS3_RS01150	COG2949	membrane
ANTHELSMS3_RS01155	COG0625	glutathione transferase activity
ANTHELSMS3_RS01160	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ANTHELSMS3_RS01165	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ANTHELSMS3_RS01170	COG0124	histidyl-tRNA synthetase
ANTHELSMS3_RS01210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ANTHELSMS3_RS01220	COG3845	ABC transporter
ANTHELSMS3_RS01225	COG4603	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS01230	COG1079	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS01250	COG0667	Aldo Keto reductase
ANTHELSMS3_RS01260	COG1201	RNA secondary structure unwinding
ANTHELSMS3_RS01305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ANTHELSMS3_RS01310	COG1605	Chorismate mutase
ANTHELSMS3_RS01310	COG0287	Prephenate dehydrogenase
ANTHELSMS3_RS01315	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ANTHELSMS3_RS01325	COG4106	trans-aconitate 2-methyltransferase activity
ANTHELSMS3_RS01330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANTHELSMS3_RS01335	COG0037	tRNA processing
ANTHELSMS3_RS01345	COG2885	chlorophyll binding
ANTHELSMS3_RS01370	COG0824	Thioesterase
ANTHELSMS3_RS01375	COG1403	HNH endonuclease
ANTHELSMS3_RS01380	COG1196	nuclear chromosome segregation
ANTHELSMS3_RS01380	COG3264	Mechanosensitive ion channel
ANTHELSMS3_RS01400	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_RS01415	COG2301	Belongs to the HpcH HpaI aldolase family
ANTHELSMS3_RS01435	COG0825	malonyl-CoA metabolic process
ANTHELSMS3_RS01455	COG1802	Transcriptional regulator
ANTHELSMS3_RS01495	COG1278	Cold shock
ANTHELSMS3_RS01515	COG4154	Belongs to the RbsD FucU family
ANTHELSMS3_RS01525	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ANTHELSMS3_RS01535	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ANTHELSMS3_RS01545	COG0804	urea catabolic process
ANTHELSMS3_RS01560	COG0832	Belongs to the urease beta subunit family
ANTHELSMS3_RS01565	COG0831	urea catabolic process
ANTHELSMS3_RS01570	COG0829	nickel cation binding
ANTHELSMS3_RS01585	COG0454	-acetyltransferase
ANTHELSMS3_RS01590	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS01605	COG0840	transmembrane signaling receptor activity
ANTHELSMS3_RS01615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_RS01630	COG0667	Aldo Keto reductase
ANTHELSMS3_RS01640	COG0765	amino acid transport
ANTHELSMS3_RS01680	COG1609	Transcriptional regulator
ANTHELSMS3_RS01685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANTHELSMS3_RS01690	COG3962	Belongs to the TPP enzyme family
ANTHELSMS3_RS01710	COG3718	enzyme involved in inositol metabolism
ANTHELSMS3_RS01715	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_RS01730	COG2816	NAD+ diphosphatase activity
ANTHELSMS3_RS01735	COG0737	Belongs to the 5'-nucleotidase family
ANTHELSMS3_RS01740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANTHELSMS3_RS01770	COG2321	neutral zinc metallopeptidase
ANTHELSMS3_RS01795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ANTHELSMS3_RS01825	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_RS01840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ANTHELSMS3_RS01845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ANTHELSMS3_RS01850	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ANTHELSMS3_RS01855	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ANTHELSMS3_RS01865	COG0280	phosphate acetyltransferase
ANTHELSMS3_RS01865	COG0281	malic enzyme
ANTHELSMS3_RS01875	COG0024	Methionine aminopeptidase
ANTHELSMS3_RS01900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ANTHELSMS3_RS01905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ANTHELSMS3_RS01930	COG3739	integral membrane protein
ANTHELSMS3_RS01970	COG0667	Aldo Keto reductase
ANTHELSMS3_RS01985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANTHELSMS3_RS01990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ANTHELSMS3_RS01995	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_RS02005	COG1047	Peptidyl-prolyl cis-trans
ANTHELSMS3_RS02015	COG0596	Alpha beta hydrolase
ANTHELSMS3_RS02025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ANTHELSMS3_RS02035	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ANTHELSMS3_RS02045	COG0640	Transcriptional regulator
ANTHELSMS3_RS02050	COG0154	amidase activity
ANTHELSMS3_RS02055	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_RS02070	COG2135	peptidase activity
ANTHELSMS3_RS02080	COG1803	Methylglyoxal synthase
ANTHELSMS3_RS02095	COG1132	(ABC) transporter
ANTHELSMS3_RS02100	COG0737	Belongs to the 5'-nucleotidase family
ANTHELSMS3_RS02120	COG0135	phosphoribosylanthranilate isomerase activity
ANTHELSMS3_RS02130	COG0776	regulation of translation
ANTHELSMS3_RS02150	COG0539	negative regulation of cytoplasmic translation
ANTHELSMS3_RS02175	COG3454	Phosphonate metabolism
ANTHELSMS3_RS02190	COG4778	phosphonate C-P lyase system protein PhnL
ANTHELSMS3_RS02195	COG0598	Magnesium transport protein CorA
ANTHELSMS3_RS02200	COG4107	phosphonate C-P lyase system protein PhnK
ANTHELSMS3_RS02205	COG3627	carbon phosphorus lyase activity
ANTHELSMS3_RS02210	COG3626	phosphonate metabolism
ANTHELSMS3_RS02220	COG3624	Phosphonate C-P lyase system protein PhnG
ANTHELSMS3_RS02225	COG2188	Transcriptional regulator
ANTHELSMS3_RS02230	COG3454	Phosphonate metabolism
ANTHELSMS3_RS02235	COG3639	organic phosphonate transmembrane transporter activity
ANTHELSMS3_RS02240	COG3639	organic phosphonate transmembrane transporter activity
ANTHELSMS3_RS02245	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ANTHELSMS3_RS02265	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ANTHELSMS3_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS02285	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS02295	COG2890	protein-(glutamine-N5) methyltransferase activity
ANTHELSMS3_RS02305	COG0142	geranyltranstransferase activity
ANTHELSMS3_RS02310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ANTHELSMS3_RS02330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ANTHELSMS3_RS02340	COG0303	'Molybdopterin
ANTHELSMS3_RS02345	COG1763	Mo-molybdopterin cofactor biosynthetic process
ANTHELSMS3_RS02350	COG0746	molybdenum cofactor guanylyltransferase activity
ANTHELSMS3_RS02355	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ANTHELSMS3_RS02385	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS02390	COG0009	L-threonylcarbamoyladenylate synthase
ANTHELSMS3_RS02395	COG1678	Uncharacterized ACR, COG1678
ANTHELSMS3_RS02415	COG0521	Mo-molybdopterin cofactor biosynthetic process
ANTHELSMS3_RS02420	COG1280	lysine exporter protein (LysE YggA)
ANTHELSMS3_RS02425	COG1573	uracil-dna glycosylase
ANTHELSMS3_RS02430	COG0540	Belongs to the ATCase OTCase family
ANTHELSMS3_RS02455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ANTHELSMS3_RS02460	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_RS02480	COG2095	MarC family integral membrane protein
ANTHELSMS3_RS02490	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ANTHELSMS3_RS02495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ANTHELSMS3_RS02500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ANTHELSMS3_RS02505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ANTHELSMS3_RS02510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANTHELSMS3_RS02520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANTHELSMS3_RS02545	COG1309	transcriptional regulator
ANTHELSMS3_RS02565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANTHELSMS3_RS02570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ANTHELSMS3_RS02575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ANTHELSMS3_RS02600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS02605	COG4172	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS02610	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS02625	COG0840	transmembrane signaling receptor activity
ANTHELSMS3_RS02630	COG3191	aminopeptidase activity
ANTHELSMS3_RS02640	COG1573	uracil-dna glycosylase
ANTHELSMS3_RS02665	COG0784	Response regulator, receiver
ANTHELSMS3_RS02665	COG4191	Histidine kinase
ANTHELSMS3_RS02685	COG0483	inositol monophosphate 1-phosphatase activity
ANTHELSMS3_RS02700	COG1840	ABC-type Fe3 transport system, periplasmic component
ANTHELSMS3_RS02710	COG1283	sodium-dependent phosphate transmembrane transporter activity
ANTHELSMS3_RS02715	COG1349	DNA-binding transcription factor activity
ANTHELSMS3_RS02725	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ANTHELSMS3_RS02730	COG3639	organic phosphonate transmembrane transporter activity
ANTHELSMS3_RS02740	COG1011	Hydrolase
ANTHELSMS3_RS02770	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS02775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_RS02780	COG1682	transport, permease protein
ANTHELSMS3_RS02785	COG1134	teichoic acid transport
ANTHELSMS3_RS02800	COG2072	flavoprotein involved in K transport
ANTHELSMS3_RS02805	COG4638	Rieske (2fe-2S)
ANTHELSMS3_RS02840	COG3842	ATPase activity
ANTHELSMS3_RS02845	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_RS02850	COG1177	transmembrane transport
ANTHELSMS3_RS02860	COG1648	precorrin-2 dehydrogenase activity
ANTHELSMS3_RS02860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ANTHELSMS3_RS02865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANTHELSMS3_RS02870	COG0243	molybdopterin cofactor binding
ANTHELSMS3_RS02875	COG2146	nitrite reductase [NAD(P)H] activity
ANTHELSMS3_RS02880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ANTHELSMS3_RS02890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_RS02890	COG1116	anion transmembrane transporter activity
ANTHELSMS3_RS02895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_RS02900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_RS02905	COG1116	anion transmembrane transporter activity
ANTHELSMS3_RS02905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_RS02910	COG3707	response regulator
ANTHELSMS3_RS02940	COG1175	transmembrane transport
ANTHELSMS3_RS02960	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_RS02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANTHELSMS3_RS02975	COG4989	oxidoreductase activity
ANTHELSMS3_RS02995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANTHELSMS3_RS03010	COG1858	cytochrome C peroxidase
ANTHELSMS3_RS03015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_RS03035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ANTHELSMS3_RS03050	COG1178	ABC-type Fe3 transport system permease component
ANTHELSMS3_RS03055	COG1840	ABC-type Fe3 transport system, periplasmic component
ANTHELSMS3_RS03060	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_RS03060	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_RS03070	COG1522	sequence-specific DNA binding
ANTHELSMS3_RS03075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ANTHELSMS3_RS03080	COG0179	Fumarylacetoacetate (FAA) hydrolase
ANTHELSMS3_RS03090	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS03100	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS03105	COG2721	sulfolactate sulfo-lyase activity
ANTHELSMS3_RS03110	COG1802	Transcriptional regulator
ANTHELSMS3_RS03125	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ANTHELSMS3_RS03130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANTHELSMS3_RS03135	COG2808	Putative FMN-binding domain
ANTHELSMS3_RS03140	COG0203	ribosomal protein L17
ANTHELSMS3_RS03145	COG0202	RNA polymerase activity
ANTHELSMS3_RS03150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ANTHELSMS3_RS03155	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ANTHELSMS3_RS03160	COG0563	adenylate kinase activity
ANTHELSMS3_RS03165	COG0201	protein transport
ANTHELSMS3_RS03170	COG0200	Binds to the 23S rRNA
ANTHELSMS3_RS03185	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ANTHELSMS3_RS03190	COG0513	Belongs to the DEAD box helicase family
ANTHELSMS3_RS03195	COG1841	ribosomal large subunit assembly
ANTHELSMS3_RS03200	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ANTHELSMS3_RS03205	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ANTHELSMS3_RS03210	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ANTHELSMS3_RS03215	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ANTHELSMS3_RS03220	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ANTHELSMS3_RS03225	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ANTHELSMS3_RS03230	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ANTHELSMS3_RS03240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ANTHELSMS3_RS03245	COG0255	Belongs to the universal ribosomal protein uL29 family
ANTHELSMS3_RS03270	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ANTHELSMS3_RS03275	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ANTHELSMS3_RS03280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ANTHELSMS3_RS03285	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ANTHELSMS3_RS03290	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ANTHELSMS3_RS03300	COG0089	rRNA binding
ANTHELSMS3_RS03305	COG0088	Forms part of the polypeptide exit tunnel
ANTHELSMS3_RS03310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ANTHELSMS3_RS03315	COG0051	transcription antitermination factor activity, RNA binding
ANTHELSMS3_RS03320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANTHELSMS3_RS03325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ANTHELSMS3_RS03330	COG0049	tRNA binding
ANTHELSMS3_RS03335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ANTHELSMS3_RS03345	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ANTHELSMS3_RS03350	COG0085	RNA polymerase activity
ANTHELSMS3_RS03355	COG0222	ribosome binding
ANTHELSMS3_RS03360	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ANTHELSMS3_RS03370	COG0784	Response regulator, receiver
ANTHELSMS3_RS03370	COG2205	protein histidine kinase activity
ANTHELSMS3_RS03380	COG0081	regulation of translation
ANTHELSMS3_RS03385	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ANTHELSMS3_RS03390	COG0250	Participates in transcription elongation, termination and antitermination
ANTHELSMS3_RS03395	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ANTHELSMS3_RS03430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANTHELSMS3_RS03440	COG2096	Adenosyltransferase
ANTHELSMS3_RS03450	COG0300	oxidoreductase activity
ANTHELSMS3_RS03460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANTHELSMS3_RS03480	COG0501	Belongs to the peptidase M48B family
ANTHELSMS3_RS03500	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_RS03510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANTHELSMS3_RS03530	COG2205	protein histidine kinase activity
ANTHELSMS3_RS03535	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_RS03540	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ANTHELSMS3_RS03550	COG3246	L-lysine catabolic process to acetate
ANTHELSMS3_RS03555	COG3485	protocatechuate 3,4-dioxygenase
ANTHELSMS3_RS03560	COG3485	protocatechuate 3,4-dioxygenase
ANTHELSMS3_RS03565	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ANTHELSMS3_RS03575	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS03590	COG2814	Major facilitator Superfamily
ANTHELSMS3_RS03605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANTHELSMS3_RS03635	COG1435	thymidine kinase activity
ANTHELSMS3_RS03670	COG0842	Transport permease protein
ANTHELSMS3_RS03685	COG0473	3-isopropylmalate dehydrogenase activity
ANTHELSMS3_RS03700	COG0683	leucine binding
ANTHELSMS3_RS03720	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS03750	COG1131	(ABC) transporter
ANTHELSMS3_RS03755	COG1116	anion transmembrane transporter activity
ANTHELSMS3_RS03780	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS03785	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_RS03810	COG0058	SHG alpha-glucan phosphorylase activity
ANTHELSMS3_RS03815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ANTHELSMS3_RS03820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANTHELSMS3_RS03825	COG0297	glycogen (starch) synthase activity
ANTHELSMS3_RS03835	COG1640	4-alpha-glucanotransferase
ANTHELSMS3_RS03840	COG0033	Phosphoglucomutase
ANTHELSMS3_RS03845	COG0779	Required for maturation of 30S ribosomal subunits
ANTHELSMS3_RS03860	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ANTHELSMS3_RS03875	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ANTHELSMS3_RS03880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ANTHELSMS3_RS03885	COG0653	protein targeting
ANTHELSMS3_RS03900	COG2003	Belongs to the UPF0758 family
ANTHELSMS3_RS03905	COG0484	heat shock protein binding
ANTHELSMS3_RS03910	COG0443	Heat shock 70 kDa protein
ANTHELSMS3_RS03950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANTHELSMS3_RS03975	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ANTHELSMS3_RS03985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANTHELSMS3_RS03990	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ANTHELSMS3_RS03995	COG1137	ATPase activity
ANTHELSMS3_RS04020	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ANTHELSMS3_RS04035	COG2885	chlorophyll binding
ANTHELSMS3_RS04040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ANTHELSMS3_RS04045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ANTHELSMS3_RS04050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANTHELSMS3_RS04060	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANTHELSMS3_RS04060	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANTHELSMS3_RS04065	COG1272	protein, Hemolysin III
ANTHELSMS3_RS04070	COG1741	Belongs to the pirin family
ANTHELSMS3_RS04080	COG1131	(ABC) transporter
ANTHELSMS3_RS04100	COG0698	ribose 5-phosphate isomerase
ANTHELSMS3_RS04110	COG0714	Associated with various cellular activities
ANTHELSMS3_RS04145	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_RS04150	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_RS04160	COG0247	lactate metabolic process
ANTHELSMS3_RS04175	COG0071	Belongs to the small heat shock protein (HSP20) family
ANTHELSMS3_RS04190	COG2304	oxidoreductase activity
ANTHELSMS3_RS04205	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_RS04250	COG0437	4 iron, 4 sulfur cluster binding
ANTHELSMS3_RS04255	COG0243	molybdopterin cofactor binding
ANTHELSMS3_RS04260	COG0280	phosphate acetyltransferase
ANTHELSMS3_RS04260	COG0857	belongs to the CobB CobQ family
ANTHELSMS3_RS04265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANTHELSMS3_RS04270	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_RS04320	COG4221	oxidoreductase activity
ANTHELSMS3_RS04340	COG0297	glycogen (starch) synthase activity
ANTHELSMS3_RS04340	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS04350	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_RS04355	COG0489	protein tyrosine kinase activity
ANTHELSMS3_RS04395	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS04410	COG0662	Cupin 2, conserved barrel domain protein
ANTHELSMS3_RS04415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANTHELSMS3_RS04420	COG2824	Alkylphosphonate utilization operon protein PhnA
ANTHELSMS3_RS04425	COG0405	Gamma-glutamyltransferase
ANTHELSMS3_RS04450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ANTHELSMS3_RS04455	COG0517	IMP dehydrogenase activity
ANTHELSMS3_RS04455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ANTHELSMS3_RS04460	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ANTHELSMS3_RS04465	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ANTHELSMS3_RS04470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANTHELSMS3_RS04490	COG3901	Regulator of nitric oxide reductase transcription
ANTHELSMS3_RS04490	COG0348	domain, Protein
ANTHELSMS3_RS04555	COG0640	Transcriptional regulator
ANTHELSMS3_RS04560	COG0701	Predicted permease
ANTHELSMS3_RS04585	COG3437	response regulator, receiver
ANTHELSMS3_RS04585	COG2205	protein histidine kinase activity
ANTHELSMS3_RS04585	COG4999	Histidine kinase
ANTHELSMS3_RS04585	COG3850	Histidine kinase
ANTHELSMS3_RS04595	COG3051	citrate lyase alpha subunit
ANTHELSMS3_RS04610	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_RS04635	COG2828	Protein conserved in bacteria
ANTHELSMS3_RS04645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANTHELSMS3_RS04650	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS04660	COG0473	3-isopropylmalate dehydrogenase activity
ANTHELSMS3_RS04670	COG1053	succinate dehydrogenase
ANTHELSMS3_RS04695	COG1802	Transcriptional regulator
ANTHELSMS3_RS04715	COG3485	protocatechuate 3,4-dioxygenase
ANTHELSMS3_RS04735	COG0778	Nitroreductase
ANTHELSMS3_RS04740	COG0179	Fumarylacetoacetate (FAA) hydrolase
ANTHELSMS3_RS04755	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_RS04775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ANTHELSMS3_RS04780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ANTHELSMS3_RS04820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ANTHELSMS3_RS04830	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ANTHELSMS3_RS04840	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS04845	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ANTHELSMS3_RS04850	COG1999	signal sequence binding
ANTHELSMS3_RS04870	COG3178	'Phosphotransferase
ANTHELSMS3_RS04875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ANTHELSMS3_RS04885	COG1074	ATP-dependent DNA helicase activity
ANTHELSMS3_RS04895	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ANTHELSMS3_RS04900	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ANTHELSMS3_RS04905	COG0754	glutathionylspermidine amidase activity
ANTHELSMS3_RS04915	COG0747	negative chemotaxis
ANTHELSMS3_RS04920	COG4172	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS04925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS04930	COG0601	transmembrane transport
ANTHELSMS3_RS04940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ANTHELSMS3_RS04950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ANTHELSMS3_RS04965	COG2226	methyltransferase
ANTHELSMS3_RS04990	COG3034	peptidoglycan biosynthetic process
ANTHELSMS3_RS05000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANTHELSMS3_RS05005	COG1132	(ABC) transporter
ANTHELSMS3_RS05010	COG1132	(ABC) transporter
ANTHELSMS3_RS05015	COG1132	(ABC) transporter
ANTHELSMS3_RS05020	COG0617	tRNA 3'-terminal CCA addition
ANTHELSMS3_RS05025	COG0494	nUDIX hydrolase
ANTHELSMS3_RS05030	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ANTHELSMS3_RS05035	COG0494	nUDIX hydrolase
ANTHELSMS3_RS05055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANTHELSMS3_RS05065	COG0137	argininosuccinate synthase activity
ANTHELSMS3_RS05080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANTHELSMS3_RS05090	COG0281	malic enzyme
ANTHELSMS3_RS05090	COG0280	phosphate acetyltransferase
ANTHELSMS3_RS05095	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ANTHELSMS3_RS05100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ANTHELSMS3_RS05110	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ANTHELSMS3_RS05115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ANTHELSMS3_RS05120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANTHELSMS3_RS05135	COG0357	Ribosomal RNA small subunit methyltransferase G
ANTHELSMS3_RS05140	COG0445	tRNA wobble uridine modification
ANTHELSMS3_RS05145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ANTHELSMS3_RS05150	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ANTHELSMS3_RS05155	COG0424	maF-like protein
ANTHELSMS3_RS05160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ANTHELSMS3_RS05165	COG0237	dephospho-CoA kinase activity
ANTHELSMS3_RS05170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ANTHELSMS3_RS05175	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ANTHELSMS3_RS05180	COG3030	protein affecting phage T7 exclusion by the F plasmid
ANTHELSMS3_RS05225	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANTHELSMS3_RS05230	COG1360	Flagellar Motor Protein
ANTHELSMS3_RS05250	COG1706	bacterial-type flagellum-dependent cell motility
ANTHELSMS3_RS05265	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ANTHELSMS3_RS05275	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ANTHELSMS3_RS05290	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ANTHELSMS3_RS05300	COG4786	Flagellar basal body rod
ANTHELSMS3_RS05305	COG4786	Flagellar basal body rod
ANTHELSMS3_RS05310	COG1987	bacterial-type flagellum assembly
ANTHELSMS3_RS05315	COG1677	Flagellar hook-basal body complex protein FliE
ANTHELSMS3_RS05320	COG1558	bacterial-type flagellum-dependent cell motility
ANTHELSMS3_RS05325	COG1815	bacterial-type flagellum-dependent cell motility
ANTHELSMS3_RS05340	COG5443	negative regulation of bacterial-type flagellum assembly
ANTHELSMS3_RS05370	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ANTHELSMS3_RS05385	COG2226	methyltransferase
ANTHELSMS3_RS05390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ANTHELSMS3_RS05400	COG0268	Binds directly to 16S ribosomal RNA
ANTHELSMS3_RS05405	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ANTHELSMS3_RS05415	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ANTHELSMS3_RS05430	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS05435	COG3708	Transcriptional regulator
ANTHELSMS3_RS05435	COG2207	Transcriptional regulator
ANTHELSMS3_RS05445	COG1320	monovalent cation:proton antiporter activity
ANTHELSMS3_RS05450	COG2212	antiporter activity
ANTHELSMS3_RS05455	COG1863	multisubunit Na H antiporter MnhE subunit
ANTHELSMS3_RS05460	COG0651	ATP synthesis coupled electron transport
ANTHELSMS3_RS05465	COG1006	Multisubunit Na H antiporter MnhC subunit
ANTHELSMS3_RS05470	COG2111	Na H antiporter
ANTHELSMS3_RS05470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ANTHELSMS3_RS05475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_RS05485	COG0725	ABC transporter, periplasmic molybdate-binding protein
ANTHELSMS3_RS05490	COG4149	molybdate abc transporter
ANTHELSMS3_RS05495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ANTHELSMS3_RS05505	COG3046	protein related to deoxyribodipyrimidine photolyase
ANTHELSMS3_RS05515	COG2197	response regulator
ANTHELSMS3_RS05545	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ANTHELSMS3_RS05555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANTHELSMS3_RS05565	COG1959	2 iron, 2 sulfur cluster binding
ANTHELSMS3_RS05570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_RS05575	COG0509	glycine decarboxylation via glycine cleavage system
ANTHELSMS3_RS05580	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANTHELSMS3_RS05580	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANTHELSMS3_RS05590	COG0784	Response regulator, receiver
ANTHELSMS3_RS05590	COG4191	Histidine kinase
ANTHELSMS3_RS05595	COG0483	inositol monophosphate 1-phosphatase activity
ANTHELSMS3_RS05605	COG4181	ATPase activity
ANTHELSMS3_RS05625	COG1376	ErfK ybiS ycfS ynhG family protein
ANTHELSMS3_RS05645	COG1766	The M ring may be actively involved in energy transduction
ANTHELSMS3_RS05655	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ANTHELSMS3_RS05660	COG1338	Plays a role in the flagellum-specific transport system
ANTHELSMS3_RS05670	COG1054	Belongs to the UPF0176 family
ANTHELSMS3_RS05675	COG0443	Heat shock 70 kDa protein
ANTHELSMS3_RS05680	COG1335	isochorismatase
ANTHELSMS3_RS05685	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ANTHELSMS3_RS05695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ANTHELSMS3_RS05700	COG0287	Prephenate dehydrogenase
ANTHELSMS3_RS05710	COG2268	Band 7 protein
ANTHELSMS3_RS05715	COG1585	Membrane protein implicated in regulation of membrane protease activity
ANTHELSMS3_RS05730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANTHELSMS3_RS05735	COG0165	Argininosuccinate lyase
ANTHELSMS3_RS05745	COG0019	diaminopimelate decarboxylase activity
ANTHELSMS3_RS05760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ANTHELSMS3_RS05770	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ANTHELSMS3_RS05790	COG0514	ATP-dependent DNA helicase (RecQ)
ANTHELSMS3_RS05795	COG3022	response to hydroperoxide
ANTHELSMS3_RS05800	COG0784	Response regulator, receiver
ANTHELSMS3_RS05800	COG2205	protein histidine kinase activity
ANTHELSMS3_RS05800	COG5002	protein histidine kinase activity
ANTHELSMS3_RS05805	COG2373	Large extracellular alpha-helical protein
ANTHELSMS3_RS05815	COG4953	penicillin-binding protein 1C
ANTHELSMS3_RS05835	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ANTHELSMS3_RS05840	COG0156	8-amino-7-oxononanoate synthase activity
ANTHELSMS3_RS05845	COG0183	Belongs to the thiolase family
ANTHELSMS3_RS05860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ANTHELSMS3_RS05870	COG0066	3-isopropylmalate dehydratase activity
ANTHELSMS3_RS05890	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS05895	COG0473	3-isopropylmalate dehydrogenase activity
ANTHELSMS3_RS05905	COG0697	spore germination
ANTHELSMS3_RS05930	COG1132	(ABC) transporter
ANTHELSMS3_RS05935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANTHELSMS3_RS05965	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_RS05990	COG2072	flavoprotein involved in K transport
ANTHELSMS3_RS05995	COG3284	Transcriptional regulator
ANTHELSMS3_RS06005	COG0798	PFAM Bile acid sodium symporter
ANTHELSMS3_RS06010	COG0431	NADPH-dependent FMN reductase
ANTHELSMS3_RS06015	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS06035	COG1175	transmembrane transport
ANTHELSMS3_RS06040	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_RS06050	COG3734	2-keto-3-deoxy-galactonokinase
ANTHELSMS3_RS06055	COG0800	Aldolase
ANTHELSMS3_RS06065	COG1136	(ABC) transporter
ANTHELSMS3_RS06080	COG2217	Heavy metal translocating P-type atpase
ANTHELSMS3_RS06085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ANTHELSMS3_RS06100	COG0560	Phosphoserine phosphatase
ANTHELSMS3_RS06100	COG3830	Belongs to the UPF0237 family
ANTHELSMS3_RS06110	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ANTHELSMS3_RS06145	COG0679	Auxin Efflux Carrier
ANTHELSMS3_RS06150	COG1266	CAAX protease self-immunity
ANTHELSMS3_RS06155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ANTHELSMS3_RS06160	COG0285	dihydrofolate synthase activity
ANTHELSMS3_RS06180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ANTHELSMS3_RS06195	COG2423	ornithine cyclodeaminase activity
ANTHELSMS3_RS06205	COG1671	Belongs to the UPF0178 family
ANTHELSMS3_RS06210	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ANTHELSMS3_RS06225	COG0129	dihydroxy-acid dehydratase activity
ANTHELSMS3_RS06250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_RS06255	COG1177	transmembrane transport
ANTHELSMS3_RS06260	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_RS06265	COG3842	ATPase activity
ANTHELSMS3_RS06290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ANTHELSMS3_RS06305	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ANTHELSMS3_RS06310	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_RS06315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANTHELSMS3_RS06320	COG3806	Anti-sigma factor
ANTHELSMS3_RS06325	COG1595	DNA-templated transcription, initiation
ANTHELSMS3_RS06345	COG4221	oxidoreductase activity
ANTHELSMS3_RS06355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ANTHELSMS3_RS06370	COG0284	orotidine-5'-phosphate decarboxylase activity
ANTHELSMS3_RS06395	COG1475	DNA binding
ANTHELSMS3_RS06400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ANTHELSMS3_RS06410	COG0069	glutamate synthase activity
ANTHELSMS3_RS06415	COG0076	glutamate decarboxylase activity
ANTHELSMS3_RS06420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ANTHELSMS3_RS06430	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ANTHELSMS3_RS06495	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS06510	COG3547	Transposase (IS116 IS110 IS902 family)
ANTHELSMS3_RS06540	COG1349	DNA-binding transcription factor activity
ANTHELSMS3_RS06550	COG1175	transmembrane transport
ANTHELSMS3_RS06555	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_RS06560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ANTHELSMS3_RS06570	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_RS06575	COG3842	ATPase activity
ANTHELSMS3_RS06580	COG0434	BtpA family
ANTHELSMS3_RS06595	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_RS06605	COG3328	transposase activity
ANTHELSMS3_RS06630	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_RS06630	COG0247	lactate metabolic process
ANTHELSMS3_RS06645	COG1228	amidohydrolase
ANTHELSMS3_RS06655	COG1414	Transcriptional regulator
ANTHELSMS3_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS06680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANTHELSMS3_RS06685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANTHELSMS3_RS06720	COG2186	Transcriptional regulator
ANTHELSMS3_RS06735	COG3842	ATPase activity
ANTHELSMS3_RS06745	COG1349	DNA-binding transcription factor activity
ANTHELSMS3_RS06770	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS06800	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS06805	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS06810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS06815	COG0601	transmembrane transport
ANTHELSMS3_RS06825	COG4166	transmembrane transport
ANTHELSMS3_RS06845	COG3547	Transposase (IS116 IS110 IS902 family)
ANTHELSMS3_RS06865	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
ANTHELSMS3_RS06875	COG0582	viral genome integration into host DNA
ANTHELSMS3_RS06920	COG1872	DUF167
ANTHELSMS3_RS06940	COG0346	lactoylglutathione lyase activity
ANTHELSMS3_RS06955	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ANTHELSMS3_RS06960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ANTHELSMS3_RS06970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ANTHELSMS3_RS06980	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ANTHELSMS3_RS06990	COG0793	Belongs to the peptidase S41A family
ANTHELSMS3_RS06995	COG1051	belongs to the nudix hydrolase family
ANTHELSMS3_RS07010	COG0557	exoribonuclease II activity
ANTHELSMS3_RS07025	COG2153	protein acetylation
ANTHELSMS3_RS07030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANTHELSMS3_RS07050	COG2171	N-acyltransferase activity
ANTHELSMS3_RS07055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANTHELSMS3_RS07070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ANTHELSMS3_RS07080	COG0288	reversible hydration of carbon dioxide
ANTHELSMS3_RS07090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ANTHELSMS3_RS07095	COG0791	NLP P60 protein
ANTHELSMS3_RS07110	COG2050	protein possibly involved in aromatic compounds catabolism
ANTHELSMS3_RS07125	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ANTHELSMS3_RS07130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANTHELSMS3_RS07140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ANTHELSMS3_RS07165	COG1115	amino acid carrier protein
ANTHELSMS3_RS07190	COG0254	rRNA binding
ANTHELSMS3_RS07195	COG0335	large ribosomal subunit rRNA binding
ANTHELSMS3_RS07210	COG0336	Belongs to the RNA methyltransferase TrmD family
ANTHELSMS3_RS07220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ANTHELSMS3_RS07225	COG0228	four-way junction DNA binding
ANTHELSMS3_RS07260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ANTHELSMS3_RS07270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ANTHELSMS3_RS07305	COG0356	it plays a direct role in the translocation of protons across the membrane
ANTHELSMS3_RS07310	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANTHELSMS3_RS07315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ANTHELSMS3_RS07320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ANTHELSMS3_RS07325	COG1192	Involved in chromosome partitioning
ANTHELSMS3_RS07360	COG3454	Phosphonate metabolism
ANTHELSMS3_RS07365	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ANTHELSMS3_RS07370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ANTHELSMS3_RS07405	COG0529	Catalyzes the synthesis of activated sulfate
ANTHELSMS3_RS07405	COG2046	Belongs to the sulfate adenylyltransferase family
ANTHELSMS3_RS07415	COG0492	ferredoxin-NADP+ reductase activity
ANTHELSMS3_RS07420	COG1522	sequence-specific DNA binding
ANTHELSMS3_RS07430	COG1496	oxidoreductase activity
ANTHELSMS3_RS07440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ANTHELSMS3_RS07450	COG1070	Carbohydrate kinase
ANTHELSMS3_RS07460	COG1183	phosphatidylcholine synthase activity
ANTHELSMS3_RS07465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANTHELSMS3_RS07470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ANTHELSMS3_RS07480	COG0564	pseudouridine synthase activity
ANTHELSMS3_RS07485	COG0546	phosphoglycolate phosphatase activity
ANTHELSMS3_RS07495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANTHELSMS3_RS07510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ANTHELSMS3_RS07515	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ANTHELSMS3_RS07525	COG0706	membrane insertase activity
ANTHELSMS3_RS07530	COG3300	MHYT domain
ANTHELSMS3_RS07530	COG5001	Diguanylate cyclase
ANTHELSMS3_RS07535	COG0037	tRNA processing
ANTHELSMS3_RS07545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ANTHELSMS3_RS07550	COG0594	ribonuclease P activity
ANTHELSMS3_RS07555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ANTHELSMS3_RS07565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANTHELSMS3_RS07570	COG5000	phosphorelay sensor kinase activity
ANTHELSMS3_RS07585	COG0154	amidase activity
ANTHELSMS3_RS07595	COG0747	negative chemotaxis
ANTHELSMS3_RS07605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS07610	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS07615	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS07620	COG0154	amidase activity
ANTHELSMS3_RS07635	COG2351	hydroxyisourate hydrolase activity
ANTHELSMS3_RS07645	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ANTHELSMS3_RS07655	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_RS07670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ANTHELSMS3_RS07690	COG1858	cytochrome C peroxidase
ANTHELSMS3_RS07715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANTHELSMS3_RS07720	COG1490	D-aminoacyl-tRNA deacylase activity
ANTHELSMS3_RS07740	COG4681	YaeQ
ANTHELSMS3_RS07760	COG3853	Toxic anion resistance protein (TelA)
ANTHELSMS3_RS07780	COG1187	pseudouridine synthase activity
ANTHELSMS3_RS07785	COG0590	tRNA wobble adenosine to inosine editing
ANTHELSMS3_RS07800	COG0408	coproporphyrinogen oxidase activity
ANTHELSMS3_RS07815	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ANTHELSMS3_RS07825	COG1686	Belongs to the peptidase S11 family
ANTHELSMS3_RS07835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ANTHELSMS3_RS07845	COG0604	alcohol dehydrogenase
ANTHELSMS3_RS07845	COG3321	synthase
ANTHELSMS3_RS07845	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS07855	COG0181	hydroxymethylbilane synthase activity
ANTHELSMS3_RS07860	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ANTHELSMS3_RS07865	COG2391	methyltransferase activity
ANTHELSMS3_RS07880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ANTHELSMS3_RS07880	COG1017	nitric oxide dioxygenase activity
ANTHELSMS3_RS07900	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ANTHELSMS3_RS07905	COG0632	four-way junction helicase activity
ANTHELSMS3_RS07915	COG2255	four-way junction helicase activity
ANTHELSMS3_RS07925	COG0180	Tryptophanyl-tRNA synthetase
ANTHELSMS3_RS07965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ANTHELSMS3_RS07975	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ANTHELSMS3_RS07980	COG0792	nuclease activity
ANTHELSMS3_RS07995	COG0606	chelatase, subunit chli
ANTHELSMS3_RS08010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ANTHELSMS3_RS08015	COG0756	dUTP diphosphatase activity
ANTHELSMS3_RS08020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ANTHELSMS3_RS08025	COG0339	signal peptide processing
ANTHELSMS3_RS08045	COG0697	spore germination
ANTHELSMS3_RS08055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ANTHELSMS3_RS08060	COG0459	protein refolding
ANTHELSMS3_RS08080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ANTHELSMS3_RS08100	COG0840	transmembrane signaling receptor activity
ANTHELSMS3_RS08105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ANTHELSMS3_RS08110	COG4143	(ABC) transporter
ANTHELSMS3_RS08115	COG1178	ABC-type Fe3 transport system permease component
ANTHELSMS3_RS08120	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ANTHELSMS3_RS08165	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_RS08180	COG3118	belongs to the thioredoxin family
ANTHELSMS3_RS08190	COG1278	Cold shock
ANTHELSMS3_RS08215	COG3093	addiction module antidote protein HigA
ANTHELSMS3_RS08275	COG0556	nucleotide-excision repair
ANTHELSMS3_RS08310	COG0514	ATP-dependent DNA helicase (RecQ)
ANTHELSMS3_RS08315	COG1064	alcohol dehydrogenase
ANTHELSMS3_RS08320	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_RS08325	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_RS08325	COG1902	pentaerythritol trinitrate reductase activity
ANTHELSMS3_RS08395	COG0235	Class ii aldolase
ANTHELSMS3_RS08430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_RS08460	COG4651	solute:proton antiporter activity
ANTHELSMS3_RS08460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ANTHELSMS3_RS08470	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS08480	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_RS08485	COG1177	transmembrane transport
ANTHELSMS3_RS08490	COG3842	ATPase activity
ANTHELSMS3_RS08500	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_RS08530	COG2186	Transcriptional regulator
ANTHELSMS3_RS08540	COG2084	Dehydrogenase
ANTHELSMS3_RS08565	COG1414	Transcriptional regulator
ANTHELSMS3_RS08595	COG1335	isochorismatase
ANTHELSMS3_RS08600	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS08610	COG1349	DNA-binding transcription factor activity
ANTHELSMS3_RS08650	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS08660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS08665	COG0601	transmembrane transport
ANTHELSMS3_RS08670	COG1335	isochorismatase
ANTHELSMS3_RS08675	COG1335	isochorismatase
ANTHELSMS3_RS08695	COG0765	amino acid transport
ANTHELSMS3_RS08700	COG0765	amino acid transport
ANTHELSMS3_RS08720	COG2188	Transcriptional regulator
ANTHELSMS3_RS08755	COG4191	Histidine kinase
ANTHELSMS3_RS08795	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS08800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_RS08810	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS08815	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_RS08815	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_RS08820	COG0183	Belongs to the thiolase family
ANTHELSMS3_RS08835	COG2188	Transcriptional regulator
ANTHELSMS3_RS08840	COG1454	alcohol dehydrogenase
ANTHELSMS3_RS08875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ANTHELSMS3_RS08880	COG1741	Belongs to the pirin family
ANTHELSMS3_RS08900	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ANTHELSMS3_RS08910	COG1116	anion transmembrane transporter activity
ANTHELSMS3_RS08915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_RS08920	COG1116	anion transmembrane transporter activity
ANTHELSMS3_RS08920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_RS08925	COG3604	Transcriptional regulator
ANTHELSMS3_RS08945	COG0251	oxidation-reduction process
ANTHELSMS3_RS09000	COG3457	Alanine racemase
ANTHELSMS3_RS09020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ANTHELSMS3_RS09080	COG0187	DNA topoisomerase II activity
ANTHELSMS3_RS09095	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ANTHELSMS3_RS09105	COG0346	lactoylglutathione lyase activity
ANTHELSMS3_RS09120	COG1846	Transcriptional regulator
ANTHELSMS3_RS09130	COG1426	Protein conserved in bacteria
ANTHELSMS3_RS09165	COG0483	inositol monophosphate 1-phosphatase activity
ANTHELSMS3_RS09180	COG0506	proline dehydrogenase activity
ANTHELSMS3_RS09180	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ANTHELSMS3_RS09180	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ANTHELSMS3_RS09185	COG1522	sequence-specific DNA binding
ANTHELSMS3_RS09205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ANTHELSMS3_RS09215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANTHELSMS3_RS09220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ANTHELSMS3_RS09230	COG2871	sodium ion transport
ANTHELSMS3_RS09240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANTHELSMS3_RS09255	COG1702	phosphate starvation-inducible protein PhoH
ANTHELSMS3_RS09260	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ANTHELSMS3_RS09265	COG1253	flavin adenine dinucleotide binding
ANTHELSMS3_RS09270	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ANTHELSMS3_RS09275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ANTHELSMS3_RS09285	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ANTHELSMS3_RS09290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ANTHELSMS3_RS09300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ANTHELSMS3_RS09305	COG1609	Transcriptional regulator
ANTHELSMS3_RS09315	COG3273	potassium ion transport
ANTHELSMS3_RS09315	COG0471	metal ion transport
ANTHELSMS3_RS09325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANTHELSMS3_RS09330	COG1126	abc transporter atp-binding protein
ANTHELSMS3_RS09335	COG0765	amino acid transport
ANTHELSMS3_RS09340	COG0765	amino acid transport
ANTHELSMS3_RS09385	COG0457	Tetratricopeptide repeat
ANTHELSMS3_RS09400	COG1802	Transcriptional regulator
ANTHELSMS3_RS09405	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_RS09410	COG3842	ATPase activity
ANTHELSMS3_RS09415	COG4209	transmembrane transport
ANTHELSMS3_RS09420	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_RS09425	COG1653	transport
ANTHELSMS3_RS09445	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS09450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANTHELSMS3_RS09470	COG2351	hydroxyisourate hydrolase activity
ANTHELSMS3_RS09475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ANTHELSMS3_RS09490	COG2897	thiosulfate sulfurtransferase activity
ANTHELSMS3_RS09500	COG0587	DNA-directed DNA polymerase activity
ANTHELSMS3_RS09520	COG1840	ABC-type Fe3 transport system, periplasmic component
ANTHELSMS3_RS09530	COG3842	ATPase activity
ANTHELSMS3_RS09560	COG0469	pyruvate kinase activity
ANTHELSMS3_RS09570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ANTHELSMS3_RS09575	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ANTHELSMS3_RS09585	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ANTHELSMS3_RS09590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ANTHELSMS3_RS09610	COG0072	phenylalanine-tRNA ligase activity
ANTHELSMS3_RS09610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANTHELSMS3_RS09635	COG0488	(ABC) transporter
ANTHELSMS3_RS09660	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ANTHELSMS3_RS09675	COG1192	Involved in chromosome partitioning
ANTHELSMS3_RS09690	COG0616	signal peptide processing
ANTHELSMS3_RS09690	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANTHELSMS3_RS09705	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS09710	COG0322	excinuclease ABC activity
ANTHELSMS3_RS09725	COG0730	response to heat
ANTHELSMS3_RS09730	COG1079	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS09735	COG4603	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS09745	COG3845	ABC transporter
ANTHELSMS3_RS09750	COG1744	ABC transporter substrate-binding protein PnrA-like
ANTHELSMS3_RS09755	COG0456	acetyltransferase
ANTHELSMS3_RS09760	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ANTHELSMS3_RS09765	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ANTHELSMS3_RS09780	COG2514	catechol 2,3-dioxygenase activity
ANTHELSMS3_RS09785	COG3383	formate dehydrogenase (NAD+) activity
ANTHELSMS3_RS09790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANTHELSMS3_RS09855	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ANTHELSMS3_RS09875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ANTHELSMS3_RS09890	COG1663	tetraacyldisaccharide 4'-kinase activity
ANTHELSMS3_RS09895	COG1519	Transferase
ANTHELSMS3_RS09910	COG0312	modulator of DNA gyrase
ANTHELSMS3_RS09920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ANTHELSMS3_RS09925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ANTHELSMS3_RS09945	COG0138	bifunctional purine biosynthesis protein purh
ANTHELSMS3_RS09950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ANTHELSMS3_RS09960	COG0612	Peptidase, M16
ANTHELSMS3_RS09965	COG0612	Peptidase, M16
ANTHELSMS3_RS09970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANTHELSMS3_RS09985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_RS09985	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ANTHELSMS3_RS10000	COG2030	dehydratase
ANTHELSMS3_RS10045	COG0405	Gamma-glutamyltransferase
ANTHELSMS3_RS10055	COG1366	Belongs to the anti-sigma-factor antagonist family
ANTHELSMS3_RS10085	COG1280	lysine exporter protein (LysE YggA)
ANTHELSMS3_RS10100	COG0564	pseudouridine synthase activity
ANTHELSMS3_RS10105	COG0640	Transcriptional regulator
ANTHELSMS3_RS10120	COG0450	alkyl hydroperoxide reductase
ANTHELSMS3_RS10130	COG0708	Exodeoxyribonuclease III
ANTHELSMS3_RS10140	COG3118	belongs to the thioredoxin family
ANTHELSMS3_RS10145	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ANTHELSMS3_RS10160	COG3591	Belongs to the peptidase S1B family
ANTHELSMS3_RS10185	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ANTHELSMS3_RS10200	COG1185	polyribonucleotide nucleotidyltransferase activity
ANTHELSMS3_RS10215	COG1764	response to oxidative stress
ANTHELSMS3_RS10220	COG1846	Transcriptional regulator
ANTHELSMS3_RS10225	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_RS10235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ANTHELSMS3_RS10245	COG3842	ATPase activity
ANTHELSMS3_RS10265	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_RS10270	COG1177	transmembrane transport
ANTHELSMS3_RS10285	COG1846	Transcriptional regulator
ANTHELSMS3_RS10290	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_RS10295	COG0123	including yeast histone deacetylase and acetoin utilization protein
ANTHELSMS3_RS10300	COG1722	exodeoxyribonuclease VII activity
ANTHELSMS3_RS10305	COG0142	geranyltranstransferase activity
ANTHELSMS3_RS10310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ANTHELSMS3_RS10350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ANTHELSMS3_RS10355	COG0776	regulation of translation
ANTHELSMS3_RS10370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANTHELSMS3_RS10380	COG1116	anion transmembrane transporter activity
ANTHELSMS3_RS10385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_RS10395	COG2884	Cell division ATP-binding protein ftsE
ANTHELSMS3_RS10435	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_RS10455	COG0045	succinate-CoA ligase (ADP-forming) activity
ANTHELSMS3_RS10465	COG0039	L-malate dehydrogenase activity
ANTHELSMS3_RS10495	COG2030	dehydratase
ANTHELSMS3_RS10545	COG0813	purine-nucleoside phosphorylase activity
ANTHELSMS3_RS10555	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ANTHELSMS3_RS10555	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ANTHELSMS3_RS10560	COG2937	Belongs to the GPAT DAPAT family
ANTHELSMS3_RS10565	COG0604	alcohol dehydrogenase
ANTHELSMS3_RS10590	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ANTHELSMS3_RS10595	COG2130	NADP-dependent
ANTHELSMS3_RS10600	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_RS10610	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS10635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANTHELSMS3_RS10640	COG0772	Belongs to the SEDS family
ANTHELSMS3_RS10645	COG0768	penicillin binding
ANTHELSMS3_RS10690	COG0625	glutathione transferase activity
ANTHELSMS3_RS10695	COG1970	mechanosensitive ion channel activity
ANTHELSMS3_RS10700	COG0686	Belongs to the AlaDH PNT family
ANTHELSMS3_RS10705	COG1522	sequence-specific DNA binding
ANTHELSMS3_RS10725	COG0348	domain, Protein
ANTHELSMS3_RS10730	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS10735	COG2010	Cytochrome c
ANTHELSMS3_RS10760	COG0384	phenazine biosynthesis protein PhzF
ANTHELSMS3_RS10765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANTHELSMS3_RS10770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANTHELSMS3_RS10775	COG4172	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS10780	COG4239	(ABC) transporter, permease
ANTHELSMS3_RS10785	COG4174	ABC transporter (Permease)
ANTHELSMS3_RS10790	COG4166	transmembrane transport
ANTHELSMS3_RS10800	COG1605	Chorismate mutase
ANTHELSMS3_RS10800	COG0077	Prephenate dehydratase
ANTHELSMS3_RS10815	COG2084	Dehydrogenase
ANTHELSMS3_RS10840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ANTHELSMS3_RS10865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_RS10875	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_RS10875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_RS10890	COG0358	DNA primase activity
ANTHELSMS3_RS10895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANTHELSMS3_RS10915	COG0432	Pfam Uncharacterised protein family UPF0047
ANTHELSMS3_RS10935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANTHELSMS3_RS10935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANTHELSMS3_RS10970	COG2391	methyltransferase activity
ANTHELSMS3_RS10985	COG0785	Cytochrome C biogenesis protein
ANTHELSMS3_RS11010	COG3258	Cytochrome c
ANTHELSMS3_RS11015	COG0737	Belongs to the 5'-nucleotidase family
ANTHELSMS3_RS11020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ANTHELSMS3_RS11035	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_RS11045	COG0740	serine-type endopeptidase activity
ANTHELSMS3_RS11050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ANTHELSMS3_RS11090	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ANTHELSMS3_RS11095	COG0439	Biotin carboxylase
ANTHELSMS3_RS11115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_RS11120	COG0410	ABC transporter
ANTHELSMS3_RS11145	COG3800	Transcriptional regulator
ANTHELSMS3_RS11145	COG1396	sequence-specific DNA binding
ANTHELSMS3_RS11160	COG5002	protein histidine kinase activity
ANTHELSMS3_RS11205	COG1305	Transglutaminase-like
ANTHELSMS3_RS11215	COG2308	Evidence 4 Homologs of previously reported genes of
ANTHELSMS3_RS11220	COG3750	Belongs to the UPF0335 family
ANTHELSMS3_RS11300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANTHELSMS3_RS11335	COG2132	Multicopper oxidase
ANTHELSMS3_RS11385	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS11400	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_RS11405	COG3246	L-lysine catabolic process to acetate
ANTHELSMS3_RS11435	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS11450	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS11465	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS11470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ANTHELSMS3_RS11475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_RS11480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANTHELSMS3_RS11485	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_RS11495	COG2084	Dehydrogenase
ANTHELSMS3_RS11510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_RS11520	COG0129	dihydroxy-acid dehydratase activity
ANTHELSMS3_RS11530	COG0697	spore germination
ANTHELSMS3_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS11545	COG2721	sulfolactate sulfo-lyase activity
ANTHELSMS3_RS11565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANTHELSMS3_RS11585	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS11590	COG3958	Transketolase
ANTHELSMS3_RS11595	COG3959	Transketolase, thiamine diphosphate binding domain
ANTHELSMS3_RS11605	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS11615	COG3246	L-lysine catabolic process to acetate
ANTHELSMS3_RS11625	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_RS11635	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS11645	COG1278	Cold shock
ANTHELSMS3_RS11650	COG1393	Belongs to the ArsC family
ANTHELSMS3_RS11670	COG3220	belongs to the UPF0276 family
ANTHELSMS3_RS11680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ANTHELSMS3_RS11705	COG3842	ATPase activity
ANTHELSMS3_RS11710	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_RS11715	COG1177	transmembrane transport
ANTHELSMS3_RS11720	COG1349	DNA-binding transcription factor activity
ANTHELSMS3_RS11730	COG3842	ATPase activity
ANTHELSMS3_RS11740	COG1175	transmembrane transport
ANTHELSMS3_RS11745	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_RS11760	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ANTHELSMS3_RS11800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ANTHELSMS3_RS11825	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ANTHELSMS3_RS11830	COG0625	glutathione transferase activity
ANTHELSMS3_RS11865	COG1802	Transcriptional regulator
ANTHELSMS3_RS11915	COG1396	sequence-specific DNA binding
ANTHELSMS3_RS11920	COG0156	8-amino-7-oxononanoate synthase activity
ANTHELSMS3_RS11925	COG1063	alcohol dehydrogenase
ANTHELSMS3_RS11955	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ANTHELSMS3_RS11965	COG3396	Phenylacetate-CoA oxygenase
ANTHELSMS3_RS11970	COG3460	Phenylacetate-CoA oxygenase
ANTHELSMS3_RS11975	COG3396	Phenylacetate-CoA oxygenase
ANTHELSMS3_RS11980	COG2151	metal-sulfur cluster biosynthetic enzyme
ANTHELSMS3_RS11985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ANTHELSMS3_RS11995	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_RS11995	COG2030	dehydratase
ANTHELSMS3_RS12000	COG3327	negative regulation of DNA-templated transcription, initiation
ANTHELSMS3_RS12010	COG3622	Belongs to the hyi family
ANTHELSMS3_RS12020	COG2066	Belongs to the glutaminase family
ANTHELSMS3_RS12030	COG0747	negative chemotaxis
ANTHELSMS3_RS12040	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS12045	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS12055	COG0747	negative chemotaxis
ANTHELSMS3_RS12065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS12090	COG3181	Tripartite tricarboxylate transporter family receptor
ANTHELSMS3_RS12120	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_RS12135	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS12145	COG0655	NAD(P)H dehydrogenase (quinone) activity
ANTHELSMS3_RS12155	COG0697	spore germination
ANTHELSMS3_RS12190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_RS12205	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS12215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS12220	COG0601	transmembrane transport
ANTHELSMS3_RS12225	COG4166	transmembrane transport
ANTHELSMS3_RS12245	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ANTHELSMS3_RS12255	COG0631	protein serine/threonine phosphatase activity
ANTHELSMS3_RS12265	COG0515	serine threonine protein kinase
ANTHELSMS3_RS12265	COG2815	serine threonine protein kinase
ANTHELSMS3_RS12275	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_RS12290	COG3483	tryptophan 2,3-dioxygenase activity
ANTHELSMS3_RS12310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANTHELSMS3_RS12330	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_RS12360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ANTHELSMS3_RS12365	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_RS12365	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_RS12370	COG5002	protein histidine kinase activity
ANTHELSMS3_RS12370	COG2176	DNA-directed DNA polymerase activity
ANTHELSMS3_RS12385	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ANTHELSMS3_RS12395	COG0563	adenylate kinase activity
ANTHELSMS3_RS12400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_RS12415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANTHELSMS3_RS12420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANTHELSMS3_RS12430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ANTHELSMS3_RS12445	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ANTHELSMS3_RS12450	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ANTHELSMS3_RS12470	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ANTHELSMS3_RS12480	COG1492	cobalamin metabolic process
ANTHELSMS3_RS12535	COG2099	Precorrin-6x reductase
ANTHELSMS3_RS12550	COG2875	Belongs to the precorrin methyltransferase family
ANTHELSMS3_RS12555	COG1797	cobyrinic acid a,c-diamide synthase activity
ANTHELSMS3_RS12560	COG1648	precorrin-2 dehydrogenase activity
ANTHELSMS3_RS12560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ANTHELSMS3_RS12590	COG0310	cobalt ion transport
ANTHELSMS3_RS12605	COG0667	Aldo Keto reductase
ANTHELSMS3_RS12650	COG1917	Cupin 2, conserved barrel domain protein
ANTHELSMS3_RS12655	COG1116	anion transmembrane transporter activity
ANTHELSMS3_RS12660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ANTHELSMS3_RS12665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_RS12670	COG0251	oxidation-reduction process
ANTHELSMS3_RS12675	COG1335	isochorismatase
ANTHELSMS3_RS12715	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_RS12730	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_RS12825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ANTHELSMS3_RS12845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ANTHELSMS3_RS12855	COG0354	folic acid binding
ANTHELSMS3_RS12865	COG1132	(ABC) transporter
ANTHELSMS3_RS12875	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ANTHELSMS3_RS12880	COG1136	(ABC) transporter
ANTHELSMS3_RS12890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ANTHELSMS3_RS12900	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ANTHELSMS3_RS12945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ANTHELSMS3_RS12960	COG2323	membrane
ANTHELSMS3_RS12965	COG0427	acetyl-CoA hydrolase
ANTHELSMS3_RS12975	COG0183	Belongs to the thiolase family
ANTHELSMS3_RS12980	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS12985	COG1113	amino acid transport
ANTHELSMS3_RS12990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ANTHELSMS3_RS12990	COG2010	Cytochrome c
ANTHELSMS3_RS12995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ANTHELSMS3_RS13030	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_RS13035	COG1129	ABC transporter
ANTHELSMS3_RS13040	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS13045	COG1879	ABC-type sugar transport system periplasmic component
ANTHELSMS3_RS13050	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS13055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_RS13085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANTHELSMS3_RS13090	COG2186	Transcriptional regulator
ANTHELSMS3_RS13115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_RS13120	COG0129	dihydroxy-acid dehydratase activity
ANTHELSMS3_RS13145	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ANTHELSMS3_RS13150	COG0709	Synthesizes selenophosphate from selenide and ATP
ANTHELSMS3_RS13155	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ANTHELSMS3_RS13160	COG2201	protein-glutamate methylesterase activity
ANTHELSMS3_RS13170	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_RS13175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ANTHELSMS3_RS13190	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_RS13200	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_RS13200	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_RS13220	COG0183	Belongs to the thiolase family
ANTHELSMS3_RS13230	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS13240	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS13245	COG0789	Transcriptional regulator
ANTHELSMS3_RS13265	COG0534	Mate efflux family protein
ANTHELSMS3_RS13270	COG1309	transcriptional regulator
ANTHELSMS3_RS13280	COG0133	tryptophan synthase activity
ANTHELSMS3_RS13300	COG0193	aminoacyl-tRNA hydrolase activity
ANTHELSMS3_RS13310	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ANTHELSMS3_RS13320	COG1304	FMN binding
ANTHELSMS3_RS13325	COG0159	tryptophan synthase activity
ANTHELSMS3_RS13330	COG2326	polyphosphate kinase activity
ANTHELSMS3_RS13340	COG0534	Mate efflux family protein
ANTHELSMS3_RS13350	COG0012	GTP binding
ANTHELSMS3_RS13370	COG0604	alcohol dehydrogenase
ANTHELSMS3_RS13375	COG0537	adenosine 5'-monophosphoramidase activity
ANTHELSMS3_RS13385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ANTHELSMS3_RS13390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANTHELSMS3_RS13395	COG0415	Belongs to the DNA photolyase family
ANTHELSMS3_RS13405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ANTHELSMS3_RS13415	COG0494	nUDIX hydrolase
ANTHELSMS3_RS13445	COG3264	Mechanosensitive ion channel
ANTHELSMS3_RS13445	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ANTHELSMS3_RS13450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ANTHELSMS3_RS13480	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ANTHELSMS3_RS13505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ANTHELSMS3_RS13515	COG0166	Belongs to the GPI family
ANTHELSMS3_RS13540	COG1138	Cytochrome C-type biogenesis protein
ANTHELSMS3_RS13545	COG3088	subunit of a heme lyase
ANTHELSMS3_RS13555	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_RS13560	COG0372	Belongs to the citrate synthase family
ANTHELSMS3_RS13565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANTHELSMS3_RS13570	COG0658	competence protein
ANTHELSMS3_RS13570	COG2333	competence protein COMEC
ANTHELSMS3_RS13575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ANTHELSMS3_RS13580	COG0303	'Molybdopterin
ANTHELSMS3_RS13585	COG0315	cyclic pyranopterin monophosphate synthase activity
ANTHELSMS3_RS13590	COG0134	indole-3-glycerol-phosphate synthase activity
ANTHELSMS3_RS13595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ANTHELSMS3_RS13600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANTHELSMS3_RS13620	COG0393	Putative heavy-metal-binding
ANTHELSMS3_RS13630	COG5012	cobalamin binding
ANTHELSMS3_RS13640	COG0646	methionine synthase
ANTHELSMS3_RS13640	COG1410	methionine synthase
ANTHELSMS3_RS13650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ANTHELSMS3_RS13650	COG0519	Catalyzes the synthesis of GMP from XMP
ANTHELSMS3_RS13655	COG3710	Transcriptional regulator
ANTHELSMS3_RS13675	COG5598	trimethylamine methyltransferase
ANTHELSMS3_RS13690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ANTHELSMS3_RS13695	COG2010	Cytochrome c
ANTHELSMS3_RS13700	COG3909	cytochrome
ANTHELSMS3_RS13710	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ANTHELSMS3_RS13715	COG2867	negative regulation of translational initiation
ANTHELSMS3_RS13730	COG0004	ammonium transporteR
ANTHELSMS3_RS13735	COG1546	Belongs to the CinA family
ANTHELSMS3_RS13745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ANTHELSMS3_RS13745	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ANTHELSMS3_RS13750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANTHELSMS3_RS13755	COG3852	Histidine kinase
ANTHELSMS3_RS13760	COG2204	response regulator
ANTHELSMS3_RS13765	COG5000	phosphorelay sensor kinase activity
ANTHELSMS3_RS13770	COG2204	response regulator
ANTHELSMS3_RS13785	COG0569	domain protein
ANTHELSMS3_RS13790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ANTHELSMS3_RS13795	COG1923	regulation of RNA biosynthetic process
ANTHELSMS3_RS13800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ANTHELSMS3_RS13815	COG2084	Dehydrogenase
ANTHELSMS3_RS13820	COG1530	ribonuclease E activity
ANTHELSMS3_RS13820	COG1530	ribonuclease E activity
ANTHELSMS3_RS13830	COG0425	Belongs to the sulfur carrier protein TusA family
ANTHELSMS3_RS13835	COG0785	Cytochrome C biogenesis protein
ANTHELSMS3_RS13850	COG3588	fructose-bisphosphate aldolase
ANTHELSMS3_RS13860	COG2378	regulation of single-species biofilm formation
ANTHELSMS3_RS13865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANTHELSMS3_RS13870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANTHELSMS3_RS13875	COG0805	protein transport
ANTHELSMS3_RS13890	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ANTHELSMS3_RS13895	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ANTHELSMS3_RS13900	COG4221	oxidoreductase activity
ANTHELSMS3_RS13920	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ANTHELSMS3_RS13950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ANTHELSMS3_RS13955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ANTHELSMS3_RS13960	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ANTHELSMS3_RS13970	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ANTHELSMS3_RS13975	COG0418	dihydroorotase activity
ANTHELSMS3_RS14040	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ANTHELSMS3_RS14060	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS14065	COG4335	DNA alkylation repair
ANTHELSMS3_RS14070	COG0501	Belongs to the peptidase M48B family
ANTHELSMS3_RS14075	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ANTHELSMS3_RS14080	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS14095	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ANTHELSMS3_RS14110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ANTHELSMS3_RS14115	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ANTHELSMS3_RS14130	COG0697	spore germination
ANTHELSMS3_RS14135	COG0837	glucose binding
ANTHELSMS3_RS14140	COG2723	6-phospho-beta-galactosidase activity
ANTHELSMS3_RS14145	COG1609	Transcriptional regulator
ANTHELSMS3_RS14150	COG1653	transport
ANTHELSMS3_RS14155	COG1175	transmembrane transport
ANTHELSMS3_RS14160	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_RS14165	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_RS14170	COG0366	Alpha amylase catalytic
ANTHELSMS3_RS14175	COG3842	ATPase activity
ANTHELSMS3_RS14225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ANTHELSMS3_RS14245	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS14250	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS14255	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ANTHELSMS3_RS14275	COG0517	IMP dehydrogenase activity
ANTHELSMS3_RS14275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ANTHELSMS3_RS14275	COG0617	tRNA 3'-terminal CCA addition
ANTHELSMS3_RS14280	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ANTHELSMS3_RS14305	COG3932	Exopolysaccharide synthesis, ExoD
ANTHELSMS3_RS14325	COG2226	methyltransferase
ANTHELSMS3_RS14335	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ANTHELSMS3_RS14355	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ANTHELSMS3_RS14365	COG3627	carbon phosphorus lyase activity
ANTHELSMS3_RS14370	COG4107	phosphonate C-P lyase system protein PhnK
ANTHELSMS3_RS14375	COG4778	phosphonate C-P lyase system protein PhnL
ANTHELSMS3_RS14380	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ANTHELSMS3_RS14385	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ANTHELSMS3_RS14395	COG3639	organic phosphonate transmembrane transporter activity
ANTHELSMS3_RS14400	COG3639	organic phosphonate transmembrane transporter activity
ANTHELSMS3_RS14410	COG1162	GTPase activity
ANTHELSMS3_RS14420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANTHELSMS3_RS14425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ANTHELSMS3_RS14435	COG0789	Transcriptional regulator
ANTHELSMS3_RS14445	COG0215	cysteine-tRNA ligase activity
ANTHELSMS3_RS14450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANTHELSMS3_RS14465	COG2814	Major facilitator Superfamily
ANTHELSMS3_RS14510	COG0739	heme binding
ANTHELSMS3_RS14515	COG2833	Protein of unknown function (DUF455)
ANTHELSMS3_RS14520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ANTHELSMS3_RS14530	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ANTHELSMS3_RS14545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANTHELSMS3_RS14560	COG2945	thiolester hydrolase activity
ANTHELSMS3_RS14565	COG1959	2 iron, 2 sulfur cluster binding
ANTHELSMS3_RS14570	COG1104	cysteine desulfurase activity
ANTHELSMS3_RS14575	COG0719	Fe-S assembly protein
ANTHELSMS3_RS14585	COG0393	Putative heavy-metal-binding
ANTHELSMS3_RS14590	COG0396	ATPase activity
ANTHELSMS3_RS14595	COG0719	Fe-S assembly protein
ANTHELSMS3_RS14610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANTHELSMS3_RS14615	COG2813	Specifically methylates the guanine in position
ANTHELSMS3_RS14640	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ANTHELSMS3_RS14645	COG1917	Cupin 2, conserved barrel domain protein
ANTHELSMS3_RS14650	COG0527	aspartate kinase activity
ANTHELSMS3_RS14670	COG0544	peptidyl-prolyl cis-trans isomerase activity
ANTHELSMS3_RS14675	COG0359	binds to the 23S rRNA
ANTHELSMS3_RS14680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ANTHELSMS3_RS14685	COG0360	Binds together with S18 to 16S ribosomal RNA
ANTHELSMS3_RS14695	COG2353	YceI-like domain
ANTHELSMS3_RS14705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ANTHELSMS3_RS14725	COG3956	TIGRFAM MazG family protein
ANTHELSMS3_RS14730	COG1473	amidohydrolase
ANTHELSMS3_RS14735	COG1473	amidohydrolase
ANTHELSMS3_RS14740	COG0010	Belongs to the arginase family
ANTHELSMS3_RS14750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ANTHELSMS3_RS14755	COG2890	protein-(glutamine-N5) methyltransferase activity
ANTHELSMS3_RS14765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ANTHELSMS3_RS14770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ANTHELSMS3_RS14780	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ANTHELSMS3_RS14795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ANTHELSMS3_RS14805	COG3577	Aspartyl protease
ANTHELSMS3_RS14810	COG2095	MarC family integral membrane protein
ANTHELSMS3_RS14815	COG0488	(ABC) transporter
ANTHELSMS3_RS14820	COG0105	UTP biosynthetic process
ANTHELSMS3_RS14840	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ANTHELSMS3_RS14860	COG4695	Portal protein
ANTHELSMS3_RS14940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ANTHELSMS3_RS14950	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_RS14960	COG0022	dehydrogenase e1 component
ANTHELSMS3_RS14960	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_RS14970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ANTHELSMS3_RS14975	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ANTHELSMS3_RS14990	COG0126	phosphoglycerate kinase activity
ANTHELSMS3_RS15015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ANTHELSMS3_RS15020	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ANTHELSMS3_RS15025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ANTHELSMS3_RS15045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ANTHELSMS3_RS15050	COG0546	phosphoglycolate phosphatase activity
ANTHELSMS3_RS15070	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS15085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_RS15090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ANTHELSMS3_RS15115	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_RS15135	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANTHELSMS3_RS15140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANTHELSMS3_RS15145	COG0649	NAD binding
ANTHELSMS3_RS15165	COG3743	rRNA binding
ANTHELSMS3_RS15165	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ANTHELSMS3_RS15170	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ANTHELSMS3_RS15170	COG3743	rRNA binding
ANTHELSMS3_RS15230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ANTHELSMS3_RS15240	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANTHELSMS3_RS15265	COG0713	ATP synthesis coupled electron transport
ANTHELSMS3_RS15280	COG1007	ATP synthesis coupled electron transport
ANTHELSMS3_RS15290	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ANTHELSMS3_RS15300	COG0513	Belongs to the DEAD box helicase family
ANTHELSMS3_RS15315	COG0343	queuine tRNA-ribosyltransferase activity
ANTHELSMS3_RS15335	COG1902	pentaerythritol trinitrate reductase activity
ANTHELSMS3_RS15340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ANTHELSMS3_RS15355	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS15360	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS15365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS15370	COG0601	transmembrane transport
ANTHELSMS3_RS15375	COG0747	negative chemotaxis
ANTHELSMS3_RS15405	COG0811	peptide transport
ANTHELSMS3_RS15415	COG2329	Antibiotic biosynthesis monooxygenase
ANTHELSMS3_RS15425	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ANTHELSMS3_RS15430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANTHELSMS3_RS15435	COG4558	Periplasmic binding protein
ANTHELSMS3_RS15440	COG3720	iron ion transport
ANTHELSMS3_RS15445	COG1629	transport
ANTHELSMS3_RS15450	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ANTHELSMS3_RS15470	COG0523	cobalamin synthesis protein
ANTHELSMS3_RS15475	COG0523	cobalamin synthesis protein
ANTHELSMS3_RS15505	COG4176	ABC-type proline glycine betaine transport system permease component
ANTHELSMS3_RS15515	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_RS15535	COG4176	ABC-type proline glycine betaine transport system permease component
ANTHELSMS3_RS15550	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ANTHELSMS3_RS15585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ANTHELSMS3_RS15585	COG3743	rRNA binding
ANTHELSMS3_RS15590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ANTHELSMS3_RS15600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ANTHELSMS3_RS15605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ANTHELSMS3_RS15610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ANTHELSMS3_RS15635	COG0352	thiamine-phosphate diphosphorylase activity
ANTHELSMS3_RS15660	COG1612	heme a metabolic process
ANTHELSMS3_RS15665	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ANTHELSMS3_RS15675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANTHELSMS3_RS15680	COG5425	PFAM Usg family protein
ANTHELSMS3_RS15700	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ANTHELSMS3_RS15725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ANTHELSMS3_RS15735	COG0248	Ppx GppA phosphatase
ANTHELSMS3_RS15740	COG5507	3-demethylubiquinone-9 3-methyltransferase
ANTHELSMS3_RS15745	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ANTHELSMS3_RS15760	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS15765	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_RS15765	COG0824	Thioesterase
ANTHELSMS3_RS15800	COG1595	DNA-templated transcription, initiation
ANTHELSMS3_RS15805	COG0156	8-amino-7-oxononanoate synthase activity
ANTHELSMS3_RS15815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ANTHELSMS3_RS15835	COG0436	Aminotransferase
ANTHELSMS3_RS15845	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ANTHELSMS3_RS15850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ANTHELSMS3_RS15920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ANTHELSMS3_RS15925	COG0513	Belongs to the DEAD box helicase family
ANTHELSMS3_RS15930	COG0626	cystathionine gamma-synthase activity
ANTHELSMS3_RS16010	COG0542	response to heat
ANTHELSMS3_RS16020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ANTHELSMS3_RS16025	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ANTHELSMS3_RS16035	COG4106	trans-aconitate 2-methyltransferase activity
ANTHELSMS3_RS16040	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ANTHELSMS3_RS16060	COG0175	sulfate reduction
ANTHELSMS3_RS16065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ANTHELSMS3_RS16075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ANTHELSMS3_RS16075	COG1648	precorrin-2 dehydrogenase activity
ANTHELSMS3_RS16080	COG1522	sequence-specific DNA binding
ANTHELSMS3_RS16085	COG2124	cytochrome p450
ANTHELSMS3_RS16100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANTHELSMS3_RS16105	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ANTHELSMS3_RS16110	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANTHELSMS3_RS16125	COG0149	triose-phosphate isomerase activity
ANTHELSMS3_RS16140	COG0316	Belongs to the HesB IscA family
ANTHELSMS3_RS16155	COG2814	Major facilitator Superfamily
ANTHELSMS3_RS16160	COG2151	metal-sulfur cluster biosynthetic enzyme
ANTHELSMS3_RS16165	COG0189	ligase activity
ANTHELSMS3_RS16165	COG4067	protein conserved in archaea
ANTHELSMS3_RS16195	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANTHELSMS3_RS16200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANTHELSMS3_RS16210	COG0482	sulfurtransferase activity
ANTHELSMS3_RS16225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ANTHELSMS3_RS16245	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ANTHELSMS3_RS16250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANTHELSMS3_RS16255	COG2264	protein methyltransferase activity
ANTHELSMS3_RS16260	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ANTHELSMS3_RS16265	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_RS16280	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ANTHELSMS3_RS16285	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ANTHELSMS3_RS16300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ANTHELSMS3_RS16305	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ANTHELSMS3_RS16320	COG1309	transcriptional regulator
ANTHELSMS3_RS16325	COG2326	polyphosphate kinase activity
ANTHELSMS3_RS16330	COG0596	Alpha beta hydrolase
ANTHELSMS3_RS16335	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ANTHELSMS3_RS16355	COG0697	spore germination
ANTHELSMS3_RS16365	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ANTHELSMS3_RS16380	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ANTHELSMS3_RS16385	COG0047	phosphoribosylformylglycinamidine synthase activity
ANTHELSMS3_RS16395	COG2204	response regulator
ANTHELSMS3_RS16415	COG2354	Protein conserved in bacteria
ANTHELSMS3_RS16425	COG0433	COG0433 Predicted ATPase
ANTHELSMS3_RS16435	COG2832	Protein of unknown function (DUF454)
ANTHELSMS3_RS16455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ANTHELSMS3_RS16460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ANTHELSMS3_RS16465	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ANTHELSMS3_RS16475	COG2166	iron-sulfur cluster assembly
ANTHELSMS3_RS16485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ANTHELSMS3_RS16500	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ANTHELSMS3_RS16505	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ANTHELSMS3_RS16510	COG0259	pyridoxamine-phosphate oxidase activity
ANTHELSMS3_RS16535	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANTHELSMS3_RS16545	COG2856	Zn peptidase
ANTHELSMS3_RS16565	COG0538	isocitrate dehydrogenase activity
ANTHELSMS3_RS16570	COG0840	transmembrane signaling receptor activity
ANTHELSMS3_RS16575	COG2814	Major facilitator Superfamily
ANTHELSMS3_RS16585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ANTHELSMS3_RS16640	COG2133	pyrroloquinoline quinone binding
ANTHELSMS3_RS16645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ANTHELSMS3_RS16655	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ANTHELSMS3_RS16680	COG1561	YicC-like family, N-terminal region
ANTHELSMS3_RS16685	COG0194	GDP metabolic process
ANTHELSMS3_RS16700	COG5002	protein histidine kinase activity
ANTHELSMS3_RS16710	COG0573	inorganic phosphate transmembrane transporter activity
ANTHELSMS3_RS16720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANTHELSMS3_RS16725	COG0704	Plays a role in the regulation of phosphate uptake
ANTHELSMS3_RS16730	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_RS16740	COG0052	Belongs to the universal ribosomal protein uS2 family
ANTHELSMS3_RS16745	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ANTHELSMS3_RS16755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ANTHELSMS3_RS16765	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS16770	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS16780	COG2313	pseudouridylate synthase activity
ANTHELSMS3_RS16795	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS16800	COG4166	transmembrane transport
ANTHELSMS3_RS16810	COG2205	protein histidine kinase activity
ANTHELSMS3_RS16920	COG3321	synthase
ANTHELSMS3_RS16920	COG0604	alcohol dehydrogenase
ANTHELSMS3_RS16925	COG3321	synthase
ANTHELSMS3_RS16925	COG0604	alcohol dehydrogenase
ANTHELSMS3_RS16940	COG0604	alcohol dehydrogenase
ANTHELSMS3_RS16940	COG3321	synthase
ANTHELSMS3_RS17010	COG4214	carbohydrate transport
ANTHELSMS3_RS17015	COG0129	dihydroxy-acid dehydratase activity
ANTHELSMS3_RS17050	COG1129	ABC transporter
ANTHELSMS3_RS17055	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS17065	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_RS17070	COG3618	amidohydrolase
ANTHELSMS3_RS17110	COG2059	Chromate
ANTHELSMS3_RS17120	COG0114	fumarate hydratase activity
ANTHELSMS3_RS17135	COG3842	ATPase activity
ANTHELSMS3_RS17150	COG0129	dihydroxy-acid dehydratase activity
ANTHELSMS3_RS17155	COG0800	Aldolase
ANTHELSMS3_RS17165	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ANTHELSMS3_RS17185	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ANTHELSMS3_RS17195	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANTHELSMS3_RS17205	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_RS17210	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS17235	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_RS17250	COG0440	acetolactate synthase activity
ANTHELSMS3_RS17285	COG1129	ABC transporter
ANTHELSMS3_RS17290	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS17295	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS17300	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS17305	COG1879	ABC-type sugar transport system periplasmic component
ANTHELSMS3_RS17320	COG0006	proline dipeptidase activity
ANTHELSMS3_RS17325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ANTHELSMS3_RS17330	COG0022	dehydrogenase e1 component
ANTHELSMS3_RS17335	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_RS17335	COG0022	dehydrogenase e1 component
ANTHELSMS3_RS17350	COG0577	efflux transmembrane transporter activity
ANTHELSMS3_RS17350	COG1136	(ABC) transporter
ANTHELSMS3_RS17375	COG0405	Gamma-glutamyltransferase
ANTHELSMS3_RS17405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_RS17410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ANTHELSMS3_RS17415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANTHELSMS3_RS17455	COG5001	Diguanylate cyclase
ANTHELSMS3_RS17455	COG3300	MHYT domain
ANTHELSMS3_RS17465	COG1305	Transglutaminase-like
ANTHELSMS3_RS17470	COG2307	Protein conserved in bacteria
ANTHELSMS3_RS17470	COG2308	Evidence 4 Homologs of previously reported genes of
ANTHELSMS3_RS17480	COG0840	transmembrane signaling receptor activity
ANTHELSMS3_RS17505	COG1217	gtp-binding protein TYPA
ANTHELSMS3_RS17520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ANTHELSMS3_RS17525	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ANTHELSMS3_RS17545	COG3386	PFAM SMP-30 Gluconolaconase
ANTHELSMS3_RS17550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_RS17560	COG0778	Nitroreductase
ANTHELSMS3_RS17575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ANTHELSMS3_RS17605	COG0488	(ABC) transporter
ANTHELSMS3_RS17625	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ANTHELSMS3_RS17630	COG0416	fatty acid biosynthetic process
ANTHELSMS3_RS17635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ANTHELSMS3_RS17640	COG0776	regulation of translation
ANTHELSMS3_RS17655	COG0717	Belongs to the dCTP deaminase family
ANTHELSMS3_RS17660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ANTHELSMS3_RS17665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ANTHELSMS3_RS17670	COG1472	Belongs to the glycosyl hydrolase 3 family
ANTHELSMS3_RS17680	COG0018	arginyl-trna synthetase
ANTHELSMS3_RS17685	COG3263	regulation of cellular component size
ANTHELSMS3_RS17690	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ANTHELSMS3_RS17730	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ANTHELSMS3_RS17750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ANTHELSMS3_RS17755	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANTHELSMS3_RS17760	COG3494	Protein of unknown function (DUF1009)
ANTHELSMS3_RS17765	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANTHELSMS3_RS17770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ANTHELSMS3_RS17780	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANTHELSMS3_RS17785	COG0750	zinc metalloprotease
ANTHELSMS3_RS17790	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ANTHELSMS3_RS17805	COG0233	cytoplasmic translational termination
ANTHELSMS3_RS17810	COG4977	sequence-specific DNA binding
ANTHELSMS3_RS17810	COG1917	Cupin 2, conserved barrel domain protein
ANTHELSMS3_RS17815	COG0528	UMP kinase activity
ANTHELSMS3_RS17835	COG0601	transmembrane transport
ANTHELSMS3_RS17840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS17860	COG0741	lytic transglycosylase activity
ANTHELSMS3_RS17865	COG0629	single-stranded DNA binding
ANTHELSMS3_RS17870	COG1994	Peptidase M50
ANTHELSMS3_RS17870	COG0517	IMP dehydrogenase activity
ANTHELSMS3_RS17875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ANTHELSMS3_RS17880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ANTHELSMS3_RS17890	COG4974	Belongs to the 'phage' integrase family
ANTHELSMS3_RS17895	COG4536	flavin adenine dinucleotide binding
ANTHELSMS3_RS17950	COG0010	Belongs to the arginase family
ANTHELSMS3_RS17970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANTHELSMS3_RS17980	COG1335	isochorismatase
ANTHELSMS3_RS17995	COG3842	ATPase activity
ANTHELSMS3_RS18015	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_RS18045	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_RS18050	COG0174	glutamine synthetase
ANTHELSMS3_RS18055	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_RS18070	COG1473	amidohydrolase
ANTHELSMS3_RS18075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_RS18085	COG4172	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS18090	COG0747	negative chemotaxis
ANTHELSMS3_RS18095	COG0601	transmembrane transport
ANTHELSMS3_RS18100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS18105	COG2391	methyltransferase activity
ANTHELSMS3_RS18120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ANTHELSMS3_RS18185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANTHELSMS3_RS18195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANTHELSMS3_RS18200	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANTHELSMS3_RS18205	COG4133	protoheme IX ABC transporter activity
ANTHELSMS3_RS18210	COG3737	Protein of unknown function (DUF498/DUF598)
ANTHELSMS3_RS18220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANTHELSMS3_RS18225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANTHELSMS3_RS18230	COG1862	Preprotein translocase
ANTHELSMS3_RS18235	COG3591	Belongs to the peptidase S1B family
ANTHELSMS3_RS18240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ANTHELSMS3_RS18260	COG1160	GTP binding
ANTHELSMS3_RS18280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANTHELSMS3_RS18295	COG0308	aminopeptidase N
ANTHELSMS3_RS18300	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS18325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ANTHELSMS3_RS18335	COG0484	heat shock protein binding
ANTHELSMS3_RS18340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANTHELSMS3_RS18345	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ANTHELSMS3_RS18355	COG1760	l-serine dehydratase
ANTHELSMS3_RS18375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANTHELSMS3_RS18395	COG2864	formate dehydrogenase
ANTHELSMS3_RS18400	COG0437	4 iron, 4 sulfur cluster binding
ANTHELSMS3_RS18445	COG0489	protein tyrosine kinase activity
ANTHELSMS3_RS18460	COG3852	Histidine kinase
ANTHELSMS3_RS18505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANTHELSMS3_RS18515	COG2183	response to ionizing radiation
ANTHELSMS3_RS18545	COG0544	peptidyl-prolyl cis-trans isomerase activity
ANTHELSMS3_RS18555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ANTHELSMS3_RS18590	COG0006	proline dipeptidase activity
ANTHELSMS3_RS18620	COG2223	nitrite transmembrane transporter activity
ANTHELSMS3_RS18630	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ANTHELSMS3_RS18660	COG1309	transcriptional regulator
ANTHELSMS3_RS18670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ANTHELSMS3_RS18670	COG2010	Cytochrome c
ANTHELSMS3_RS18675	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ANTHELSMS3_RS18680	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ANTHELSMS3_RS18690	COG5265	(ABC) transporter
ANTHELSMS3_RS18705	COG2962	Rard protein
ANTHELSMS3_RS18735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_RS18735	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_RS18750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_RS18760	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ANTHELSMS3_RS18780	COG0730	response to heat
ANTHELSMS3_RS18785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANTHELSMS3_RS18795	COG2828	Protein conserved in bacteria
ANTHELSMS3_RS18815	COG0642	Histidine kinase
ANTHELSMS3_RS18820	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS18835	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ANTHELSMS3_RS18840	COG0702	epimerase
ANTHELSMS3_RS18845	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS18855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_RS18860	COG1116	anion transmembrane transporter activity
ANTHELSMS3_RS18860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_RS18885	COG0189	ligase activity
ANTHELSMS3_RS19005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANTHELSMS3_RS19025	COG3239	Fatty acid desaturase
ANTHELSMS3_RS19060	COG0590	tRNA wobble adenosine to inosine editing
ANTHELSMS3_RS19065	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS19070	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS19075	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_RS19085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS19090	COG0601	transmembrane transport
ANTHELSMS3_RS19095	COG0747	negative chemotaxis
ANTHELSMS3_RS19100	COG2186	Transcriptional regulator
ANTHELSMS3_RS19105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ANTHELSMS3_RS19175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ANTHELSMS3_RS19200	COG0783	Belongs to the Dps family
ANTHELSMS3_RS19240	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS19250	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_RS19270	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_RS19275	COG3321	synthase
ANTHELSMS3_RS19275	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS19275	COG0604	alcohol dehydrogenase
ANTHELSMS3_RS19315	COG2132	Multicopper oxidase
ANTHELSMS3_RS19335	COG2010	Cytochrome c
ANTHELSMS3_RS19345	COG0714	Associated with various cellular activities
ANTHELSMS3_RS19380	COG0351	phosphomethylpyrimidine kinase
ANTHELSMS3_RS19395	COG2022	thiamine diphosphate biosynthetic process
ANTHELSMS3_RS19410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_RS19415	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ANTHELSMS3_RS19420	COG1116	anion transmembrane transporter activity
ANTHELSMS3_RS19430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_RS19485	COG3547	Transposase (IS116 IS110 IS902 family)
ANTHELSMS3_RS19515	COG0321	lipoyl(octanoyl) transferase activity
ANTHELSMS3_RS19555	COG0505	Belongs to the CarA family
ANTHELSMS3_RS19565	COG1802	Transcriptional regulator
ANTHELSMS3_RS19635	COG0752	glycyl-tRNA synthetase alpha subunit
ANTHELSMS3_RS19645	COG0751	glycine-tRNA ligase activity
ANTHELSMS3_RS19650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANTHELSMS3_RS19650	COG0574	Belongs to the PEP-utilizing enzyme family
ANTHELSMS3_RS19660	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ANTHELSMS3_RS19665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ANTHELSMS3_RS19685	COG0442	prolyl-tRNA aminoacylation
ANTHELSMS3_RS19695	COG0628	permease
ANTHELSMS3_RS19705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ANTHELSMS3_RS19715	COG0248	Ppx GppA phosphatase
ANTHELSMS3_RS19730	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ANTHELSMS3_RS19745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ANTHELSMS3_RS19745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ANTHELSMS3_RS19770	COG4770	biotin carboxylase activity
ANTHELSMS3_RS19800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ANTHELSMS3_RS19805	COG2814	Major facilitator Superfamily
ANTHELSMS3_RS19810	COG3800	Transcriptional regulator
ANTHELSMS3_RS19810	COG1396	sequence-specific DNA binding
ANTHELSMS3_RS19825	COG0154	amidase activity
ANTHELSMS3_RS19830	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ANTHELSMS3_RS19840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ANTHELSMS3_RS19865	COG2873	o-acetylhomoserine
ANTHELSMS3_RS19870	COG2968	Membrane
ANTHELSMS3_RS19885	COG1522	sequence-specific DNA binding
ANTHELSMS3_RS19890	COG0210	DNA helicase
ANTHELSMS3_RS19910	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ANTHELSMS3_RS19920	COG0346	lactoylglutathione lyase activity
ANTHELSMS3_RS19940	COG0131	Imidazoleglycerol-phosphate dehydratase
ANTHELSMS3_RS19945	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ANTHELSMS3_RS19960	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ANTHELSMS3_RS19970	COG0107	imidazoleglycerol-phosphate synthase activity
ANTHELSMS3_RS19975	COG0140	phosphoribosyl-ATP diphosphatase activity
ANTHELSMS3_RS20030	COG0552	protein localization to endoplasmic reticulum
ANTHELSMS3_RS20050	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS20060	COG0670	Belongs to the BI1 family
ANTHELSMS3_RS20070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ANTHELSMS3_RS20080	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_RS20135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANTHELSMS3_RS20145	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_RS20165	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS20180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANTHELSMS3_RS20205	COG0589	response to stress
ANTHELSMS3_RS20215	COG0729	surface antigen
ANTHELSMS3_RS20220	COG1309	transcriptional regulator
ANTHELSMS3_RS20240	COG0668	transmembrane transport
ANTHELSMS3_RS20310	COG0010	Belongs to the arginase family
ANTHELSMS3_RS20325	COG3214	Protein conserved in bacteria
ANTHELSMS3_RS20330	COG0179	Fumarylacetoacetate (FAA) hydrolase
ANTHELSMS3_RS20345	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ANTHELSMS3_RS20360	COG0346	lactoylglutathione lyase activity
ANTHELSMS3_RS20370	COG0459	protein refolding
ANTHELSMS3_RS20400	COG3350	monooxygenase activity
ANTHELSMS3_RS20445	COG3257	ureidoglycine aminohydrolase activity
ANTHELSMS3_RS20450	COG1414	Transcriptional regulator
ANTHELSMS3_RS20455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ANTHELSMS3_RS20460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANTHELSMS3_RS20465	COG3616	Alanine racemase, N-terminal domain
ANTHELSMS3_RS20470	COG2423	ornithine cyclodeaminase activity
ANTHELSMS3_RS20485	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ANTHELSMS3_RS20495	COG2351	hydroxyisourate hydrolase activity
ANTHELSMS3_RS20500	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS20510	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS20515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANTHELSMS3_RS20525	COG0765	amino acid transport
ANTHELSMS3_RS20530	COG0765	amino acid transport
ANTHELSMS3_RS20540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANTHELSMS3_RS20545	COG3246	L-lysine catabolic process to acetate
ANTHELSMS3_RS20555	COG4191	Histidine kinase
ANTHELSMS3_RS20555	COG0784	Response regulator, receiver
ANTHELSMS3_RS20565	COG1686	Belongs to the peptidase S11 family
ANTHELSMS3_RS20570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ANTHELSMS3_RS20580	COG0489	protein tyrosine kinase activity
ANTHELSMS3_RS20595	COG0525	valine-tRNA ligase activity
ANTHELSMS3_RS20610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ANTHELSMS3_RS20620	COG1469	GTP cyclohydrolase I activity
ANTHELSMS3_RS20645	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ANTHELSMS3_RS20650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ANTHELSMS3_RS20685	COG1793	dna ligase
ANTHELSMS3_RS20715	COG0386	Belongs to the glutathione peroxidase family
ANTHELSMS3_RS20735	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_RS20740	COG3119	arylsulfatase activity
ANTHELSMS3_RS20745	COG1309	transcriptional regulator
ANTHELSMS3_RS20780	COG3920	Histidine kinase
ANTHELSMS3_RS20785	COG0217	transcriptional regulatory protein
ANTHELSMS3_RS20795	COG3273	potassium ion transport
ANTHELSMS3_RS20795	COG0471	metal ion transport
ANTHELSMS3_RS20805	COG1692	metallophosphoesterase
ANTHELSMS3_RS20825	COG0587	DNA-directed DNA polymerase activity
ANTHELSMS3_RS20845	COG0330	HflC and HflK could
ANTHELSMS3_RS20850	COG0330	HflC and HflK could
ANTHELSMS3_RS20865	COG0659	secondary active sulfate transmembrane transporter activity
ANTHELSMS3_RS20870	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ANTHELSMS3_RS20925	COG3103	Sh3 type 3 domain protein
ANTHELSMS3_RS20925	COG0791	NLP P60 protein
ANTHELSMS3_RS20925	COG1388	LysM domain
ANTHELSMS3_RS20935	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_RS20945	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANTHELSMS3_RS20950	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ANTHELSMS3_RS20955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ANTHELSMS3_RS20960	COG0849	cell division
ANTHELSMS3_RS20965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ANTHELSMS3_RS20970	COG1181	Belongs to the D-alanine--D-alanine ligase family
ANTHELSMS3_RS20975	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ANTHELSMS3_RS20990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ANTHELSMS3_RS20995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ANTHELSMS3_RS21005	COG2081	HI0933 family
ANTHELSMS3_RS21010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ANTHELSMS3_RS21015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ANTHELSMS3_RS21025	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ANTHELSMS3_RS21040	COG0275	rRNA processing
ANTHELSMS3_RS21050	COG0811	peptide transport
ANTHELSMS3_RS21070	COG0084	hydrolase, TatD family'
ANTHELSMS3_RS21075	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ANTHELSMS3_RS21075	COG0321	lipoyl(octanoyl) transferase activity
ANTHELSMS3_RS21085	COG0697	spore germination
ANTHELSMS3_RS21095	COG2239	Acts as a magnesium transporter
ANTHELSMS3_RS21100	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_RS21125	COG0504	CTP synthase activity
ANTHELSMS3_RS21140	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ANTHELSMS3_RS21170	COG4215	(ABC) transporter
ANTHELSMS3_RS21175	COG4160	amino acid transport
ANTHELSMS3_RS21185	COG0174	glutamine synthetase
ANTHELSMS3_RS21190	COG0519	Catalyzes the synthesis of GMP from XMP
ANTHELSMS3_RS21190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ANTHELSMS3_RS21195	COG0174	glutamine synthetase
ANTHELSMS3_RS21200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_RS21205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ANTHELSMS3_RS21215	COG1570	exodeoxyribonuclease VII activity
ANTHELSMS3_RS21220	COG0151	Belongs to the GarS family
ANTHELSMS3_RS21250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ANTHELSMS3_RS21260	COG2340	Cysteine-rich secretory protein family
ANTHELSMS3_RS21270	COG0483	inositol monophosphate 1-phosphatase activity
ANTHELSMS3_RS21280	COG0604	alcohol dehydrogenase
ANTHELSMS3_RS21280	COG3321	synthase
ANTHELSMS3_RS21280	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS21310	COG0564	pseudouridine synthase activity
ANTHELSMS3_RS21320	COG3971	2-oxopent-4-enoate hydratase activity
ANTHELSMS3_RS21325	COG0179	Fumarylacetoacetate (FAA) hydrolase
ANTHELSMS3_RS21335	COG1846	Transcriptional regulator
ANTHELSMS3_RS21375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_RS21385	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_RS21390	COG0456	acetyltransferase
ANTHELSMS3_RS21435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ANTHELSMS3_RS21440	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ANTHELSMS3_RS21445	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANTHELSMS3_RS21445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANTHELSMS3_RS21455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ANTHELSMS3_RS21460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANTHELSMS3_RS21465	COG1121	(ABC) transporter
ANTHELSMS3_RS21475	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ANTHELSMS3_RS21480	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ANTHELSMS3_RS21490	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ANTHELSMS3_RS21500	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ANTHELSMS3_RS21505	COG1530	ribonuclease E activity
ANTHELSMS3_RS21515	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ANTHELSMS3_RS21520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ANTHELSMS3_RS21540	COG5328	Belongs to the UPF0262 family
ANTHELSMS3_RS21550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ANTHELSMS3_RS21560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ANTHELSMS3_RS21575	COG1519	Transferase
ANTHELSMS3_RS21585	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS21600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANTHELSMS3_RS21625	COG0659	secondary active sulfate transmembrane transporter activity
ANTHELSMS3_RS21635	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ANTHELSMS3_RS21645	COG1280	lysine exporter protein (LysE YggA)
ANTHELSMS3_RS21700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANTHELSMS3_RS21710	COG0758	DNA mediated transformation
ANTHELSMS3_RS21715	COG0312	modulator of DNA gyrase
ANTHELSMS3_RS21725	COG0109	protoheme IX farnesyltransferase activity
ANTHELSMS3_RS21735	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ANTHELSMS3_RS21745	COG3346	SURF1 family
ANTHELSMS3_RS21755	COG0612	Peptidase, M16
ANTHELSMS3_RS21770	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_RS21800	COG4964	Belongs to the GSP D family
ANTHELSMS3_RS21870	COG3794	PFAM blue (type 1) copper domain protein
ANTHELSMS3_RS21885	COG0577	efflux transmembrane transporter activity
ANTHELSMS3_RS21890	COG1136	(ABC) transporter
ANTHELSMS3_RS21895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANTHELSMS3_RS21900	COG0006	proline dipeptidase activity
ANTHELSMS3_RS21920	COG1063	alcohol dehydrogenase
ANTHELSMS3_RS21925	COG4221	oxidoreductase activity
ANTHELSMS3_RS21940	COG0546	phosphoglycolate phosphatase activity
ANTHELSMS3_RS21940	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ANTHELSMS3_RS21945	COG3622	Belongs to the hyi family
ANTHELSMS3_RS21980	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_RS21995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANTHELSMS3_RS22005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS22010	COG0601	transmembrane transport
ANTHELSMS3_RS22015	COG0747	negative chemotaxis
ANTHELSMS3_RS22020	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS22035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ANTHELSMS3_RS22040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANTHELSMS3_RS22045	COG1454	alcohol dehydrogenase
ANTHELSMS3_RS22050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANTHELSMS3_RS22055	COG2186	Transcriptional regulator
ANTHELSMS3_RS22060	COG3395	kinase activity
ANTHELSMS3_RS22065	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS22070	COG1802	Transcriptional regulator
ANTHELSMS3_RS22075	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_RS22100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_RS22115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANTHELSMS3_RS22120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANTHELSMS3_RS22130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ANTHELSMS3_RS22135	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_RS22190	COG0546	phosphoglycolate phosphatase activity
ANTHELSMS3_RS22235	COG0596	Alpha beta hydrolase
ANTHELSMS3_RS22240	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS22245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ANTHELSMS3_RS22250	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ANTHELSMS3_RS22265	COG0457	Tetratricopeptide repeat
ANTHELSMS3_RS22280	COG0481	GTPase activity
ANTHELSMS3_RS22285	COG1943	Transposase
ANTHELSMS3_RS22305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ANTHELSMS3_RS22325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ANTHELSMS3_RS22330	COG1703	isobutyryl-CoA mutase activity
ANTHELSMS3_RS22335	COG1643	Atp-dependent helicase
ANTHELSMS3_RS22340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ANTHELSMS3_RS22345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ANTHELSMS3_RS22360	COG1473	amidohydrolase
ANTHELSMS3_RS22385	COG0101	tRNA pseudouridine synthase activity
ANTHELSMS3_RS22390	COG3106	COG3106 Predicted ATPase
ANTHELSMS3_RS22400	COG3768	UPF0283 membrane protein
ANTHELSMS3_RS22430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ANTHELSMS3_RS22445	COG2197	response regulator
ANTHELSMS3_RS22455	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_RS22460	COG1720	tRNA m6t6A37 methyltransferase activity
ANTHELSMS3_RS22465	COG0688	phosphatidylethanolamine metabolic process
ANTHELSMS3_RS22475	COG3547	Transposase (IS116 IS110 IS902 family)
ANTHELSMS3_RS22510	COG3654	unkown
ANTHELSMS3_RS22545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ANTHELSMS3_RS22575	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS22580	COG1129	ABC transporter
ANTHELSMS3_RS22595	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_RS22600	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS22605	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS22630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ANTHELSMS3_RS22635	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_RS22645	COG0765	amino acid transport
ANTHELSMS3_RS22655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANTHELSMS3_RS22660	COG2186	Transcriptional regulator
ANTHELSMS3_RS22675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ANTHELSMS3_RS22675	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ANTHELSMS3_RS22725	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS22730	COG2273	Hydrolase Family 16
ANTHELSMS3_RS22735	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS22805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANTHELSMS3_RS22815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ANTHELSMS3_RS22815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANTHELSMS3_RS22820	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS22835	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_RS22850	COG3547	Transposase (IS116 IS110 IS902 family)
ANTHELSMS3_RS22865	COG0747	negative chemotaxis
ANTHELSMS3_RS22870	COG0601	transmembrane transport
ANTHELSMS3_RS22875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS22880	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS22885	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS22890	COG1396	sequence-specific DNA binding
ANTHELSMS3_RS22900	COG0726	polysaccharide deacetylase
ANTHELSMS3_RS22910	COG0765	amino acid transport
ANTHELSMS3_RS22915	COG0765	amino acid transport
ANTHELSMS3_RS22930	COG1177	transmembrane transport
ANTHELSMS3_RS22935	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_RS22940	COG3842	ATPase activity
ANTHELSMS3_RS22960	COG3433	isochorismatase activity
ANTHELSMS3_RS22960	COG1535	isochorismatase
ANTHELSMS3_RS23020	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_RS23025	COG2205	protein histidine kinase activity
ANTHELSMS3_RS23045	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS23050	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS23055	COG3307	-O-antigen
ANTHELSMS3_RS23065	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ANTHELSMS3_RS23070	COG4372	Transposase
ANTHELSMS3_RS23080	COG2433	Pfam Transposase IS66
ANTHELSMS3_RS23090	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_RS23105	COG0006	proline dipeptidase activity
ANTHELSMS3_RS23110	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS23115	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_RS23120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_RS23125	COG0601	transmembrane transport
ANTHELSMS3_RS23130	COG4166	transmembrane transport
ANTHELSMS3_RS23140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_RS23150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANTHELSMS3_RS23155	COG1902	pentaerythritol trinitrate reductase activity
ANTHELSMS3_RS23170	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS23175	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_RS23190	COG1414	Transcriptional regulator
ANTHELSMS3_RS23200	COG1175	transmembrane transport
ANTHELSMS3_RS23205	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_RS23210	COG3842	ATPase activity
ANTHELSMS3_RS23215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANTHELSMS3_RS23220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANTHELSMS3_RS23230	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS23245	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANTHELSMS3_RS23270	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_RS23280	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_RS23310	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ANTHELSMS3_RS23315	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ANTHELSMS3_RS23340	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS23345	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ANTHELSMS3_RS23360	COG1609	Transcriptional regulator
ANTHELSMS3_RS23370	COG1175	transmembrane transport
ANTHELSMS3_RS23375	COG3833	ABC-type maltose transport systems, permease component
ANTHELSMS3_RS23385	COG0584	glycerophosphoryl diester phosphodiesterase
ANTHELSMS3_RS23390	COG1609	Transcriptional regulator
ANTHELSMS3_RS23395	COG0483	inositol monophosphate 1-phosphatase activity
ANTHELSMS3_RS23400	COG1053	succinate dehydrogenase
ANTHELSMS3_RS23420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_RS23425	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_RS23440	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS23445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANTHELSMS3_RS23460	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ANTHELSMS3_RS23470	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_RS23495	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_RS23500	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS23520	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ANTHELSMS3_RS23540	COG3609	addiction module antidote protein, CC2985 family
ANTHELSMS3_RS23590	COG2132	Multicopper oxidase
ANTHELSMS3_RS23595	COG1321	iron dependent repressor
ANTHELSMS3_RS23630	COG3034	peptidoglycan biosynthetic process
ANTHELSMS3_RS23635	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ANTHELSMS3_RS23640	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ANTHELSMS3_RS23660	COG1999	signal sequence binding
ANTHELSMS3_RS23670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANTHELSMS3_RS23670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANTHELSMS3_RS23680	COG1999	signal sequence binding
ANTHELSMS3_RS23685	COG0789	Transcriptional regulator
ANTHELSMS3_RS23700	COG1230	cation diffusion facilitator family transporter
ANTHELSMS3_RS23735	COG0398	Pfam SNARE associated Golgi protein
ANTHELSMS3_RS23770	COG1138	Cytochrome C-type biogenesis protein
ANTHELSMS3_RS23775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANTHELSMS3_RS23780	COG3088	subunit of a heme lyase
ANTHELSMS3_RS23785	COG4235	cytochrome complex assembly
ANTHELSMS3_RS23850	COG2010	Cytochrome c
ANTHELSMS3_RS23855	COG2132	Multicopper oxidase
ANTHELSMS3_RS23865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANTHELSMS3_RS23865	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANTHELSMS3_RS23965	COG1595	DNA-templated transcription, initiation
ANTHELSMS3_RS24015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANTHELSMS3_RS24030	COG3177	Filamentation induced by cAMP protein fic
ANTHELSMS3_RS24080	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_RS24095	COG1802	Transcriptional regulator
ANTHELSMS3_RS24100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANTHELSMS3_RS24110	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_RS24125	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_RS24130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_RS24135	COG2423	ornithine cyclodeaminase activity
ANTHELSMS3_RS24140	COG1126	abc transporter atp-binding protein
ANTHELSMS3_RS24150	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_RS24165	COG0154	amidase activity
ANTHELSMS3_RS24200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_RS24220	COG0559	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_RS24230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ANTHELSMS3_RS24245	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS24250	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS24265	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_RS24270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ANTHELSMS3_RS24275	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ANTHELSMS3_RS24280	COG2301	Belongs to the HpcH HpaI aldolase family
ANTHELSMS3_RS24320	COG0625	glutathione transferase activity
ANTHELSMS3_RS24325	COG0625	glutathione transferase activity
ANTHELSMS3_RS24330	COG0346	lactoylglutathione lyase activity
ANTHELSMS3_RS24345	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS24365	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_RS24375	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_RS24410	COG0154	amidase activity
ANTHELSMS3_RS24420	COG5285	phytanoyl-CoA dioxygenase
ANTHELSMS3_RS24445	COG1414	Transcriptional regulator
ANTHELSMS3_RS24480	COG1682	transport, permease protein
ANTHELSMS3_RS24510	COG1192	Involved in chromosome partitioning
ANTHELSMS3_RS24530	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ANTHELSMS3_RS24530	COG0662	Cupin 2, conserved barrel domain protein
ANTHELSMS3_RS24545	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ANTHELSMS3_RS24560	COG1132	(ABC) transporter
ANTHELSMS3_RS24595	COG1132	(ABC) transporter
ANTHELSMS3_RS24610	COG1442	glycosyl transferase family 8
ANTHELSMS3_RS24610	COG1216	Glycosyl transferase, family 2
ANTHELSMS3_RS24620	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS24630	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_RS24645	COG0489	protein tyrosine kinase activity
ANTHELSMS3_RS24650	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ANTHELSMS3_RS24660	COG1216	Glycosyl transferase, family 2
ANTHELSMS3_RS24775	COG3321	synthase
ANTHELSMS3_RS24775	COG0604	alcohol dehydrogenase
ANTHELSMS3_RS24775	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS24790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANTHELSMS3_RS24795	COG2186	Transcriptional regulator
ANTHELSMS3_RS24800	COG2186	Transcriptional regulator
ANTHELSMS3_RS24815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_RS24820	COG0604	alcohol dehydrogenase
ANTHELSMS3_RS24825	COG1082	Xylose isomerase domain protein TIM barrel
ANTHELSMS3_RS24825	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ANTHELSMS3_RS24845	COG3181	Tripartite tricarboxylate transporter family receptor
ANTHELSMS3_RS24855	COG1053	succinate dehydrogenase
ANTHELSMS3_RS24865	COG1309	transcriptional regulator
ANTHELSMS3_RS24895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANTHELSMS3_RS24920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_RS24935	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS24935	COG3347	Dehydrogenase
ANTHELSMS3_RS24940	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ANTHELSMS3_RS24955	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_RS24960	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS24965	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_RS25000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANTHELSMS3_RS25040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ANTHELSMS3_RS25045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANTHELSMS3_RS25075	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANTHELSMS3_RS25145	COG2186	Transcriptional regulator
ANTHELSMS3_RS25150	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ANTHELSMS3_RS25160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ANTHELSMS3_RS25165	COG1335	isochorismatase
ANTHELSMS3_RS25175	COG1177	transmembrane transport
ANTHELSMS3_RS25180	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_RS25190	COG3842	ATPase activity
ANTHELSMS3_RS25195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ANTHELSMS3_RS25200	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_RS25210	COG1177	transmembrane transport
ANTHELSMS3_RS25215	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_RS25220	COG3842	ATPase activity
ANTHELSMS3_RS25230	COG0019	diaminopimelate decarboxylase activity
ANTHELSMS3_RS25240	COG2226	methyltransferase
ANTHELSMS3_RS25275	COG3609	addiction module antidote protein, CC2985 family
ANTHELSMS3_RS25280	COG1414	Transcriptional regulator
ANTHELSMS3_RS25290	COG1192	Involved in chromosome partitioning
ANTHELSMS3_RS25330	COG0443	Heat shock 70 kDa protein
ANTHELSMS3_RS25335	COG0210	DNA helicase