locus-tag	class	description
DEH84_RS00010	COG0592	DNA-directed DNA polymerase activity
DEH84_RS00025	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
DEH84_RS00030	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
DEH84_RS00060	COG1289	transmembrane transporter activity
DEH84_RS00100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEH84_RS00115	COG2890	protein-(glutamine-N5) methyltransferase activity
DEH84_RS00130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DEH84_RS00165	COG0720	synthase
DEH84_RS00195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEH84_RS00220	COG2824	Alkylphosphonate utilization operon protein PhnA
DEH84_RS00240	COG2223	nitrite transmembrane transporter activity
DEH84_RS00260	COG0604	alcohol dehydrogenase
DEH84_RS00275	COG2267	carboxylic ester hydrolase activity
DEH84_RS00290	COG0436	Aminotransferase
DEH84_RS00295	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEH84_RS00325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DEH84_RS00345	COG1136	(ABC) transporter
DEH84_RS00355	COG2207	Transcriptional regulator
DEH84_RS00365	COG0531	amino acid
DEH84_RS00375	COG4302	ethanolamine ammonia-lyase activity
DEH84_RS00380	COG1760	l-serine dehydratase
DEH84_RS00440	COG3284	Transcriptional regulator
DEH84_RS00445	COG4772	TonB-dependent receptor
DEH84_RS00470	COG3634	alkyl hydroperoxide reductase activity
DEH84_RS00485	COG2195	Cleaves the N-terminal amino acid of tripeptides
DEH84_RS00500	COG0427	acetyl-CoA hydrolase
DEH84_RS00505	COG0583	DNA-binding transcription factor activity
DEH84_RS00530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DEH84_RS00545	COG0657	acetylesterase activity
DEH84_RS00555	COG2197	response regulator
DEH84_RS00560	COG0840	transmembrane signaling receptor activity
DEH84_RS00570	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
DEH84_RS00600	COG2967	ApaG domain
DEH84_RS00605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DEH84_RS00630	COG3851	Histidine kinase
DEH84_RS00655	COG4774	siderophore transport
DEH84_RS00660	COG0436	Aminotransferase
DEH84_RS00690	COG0443	Heat shock 70 kDa protein
DEH84_RS00705	COG0546	phosphoglycolate phosphatase activity
DEH84_RS00730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DEH84_RS00735	COG0134	indole-3-glycerol-phosphate synthase activity
DEH84_RS00740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEH84_RS00810	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEH84_RS00835	COG0081	regulation of translation
DEH84_RS00840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEH84_RS00845	COG0222	ribosome binding
DEH84_RS00850	COG0085	RNA polymerase activity
DEH84_RS00855	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEH84_RS00865	COG2814	Major facilitator Superfamily
DEH84_RS00870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEH84_RS00890	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DEH84_RS00895	COG0049	tRNA binding
DEH84_RS00900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEH84_RS00905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEH84_RS00910	COG0051	transcription antitermination factor activity, RNA binding
DEH84_RS00915	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEH84_RS00920	COG0088	Forms part of the polypeptide exit tunnel
DEH84_RS00925	COG0089	rRNA binding
DEH84_RS00930	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEH84_RS00935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEH84_RS00940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEH84_RS00945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEH84_RS00950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEH84_RS00955	COG0255	Belongs to the universal ribosomal protein uL29 family
DEH84_RS00960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEH84_RS00965	COG0678	peroxiredoxin activity
DEH84_RS00975	COG0167	dihydroorotate dehydrogenase activity
DEH84_RS00995	COG1309	transcriptional regulator
DEH84_RS01000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEH84_RS01005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEH84_RS01010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEH84_RS01020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DEH84_RS01030	COG0642	Histidine kinase
DEH84_RS01060	COG2205	protein histidine kinase activity
DEH84_RS01060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEH84_RS01090	COG0392	lysyltransferase activity
DEH84_RS01095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DEH84_RS01100	COG3568	Endonuclease Exonuclease Phosphatase
DEH84_RS01130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DEH84_RS01140	COG0583	DNA-binding transcription factor activity
DEH84_RS01155	COG0515	serine threonine protein kinase
DEH84_RS01155	COG2815	serine threonine protein kinase
DEH84_RS01160	COG0018	arginyl-trna synthetase
DEH84_RS01180	COG1137	ATPase activity
DEH84_RS01185	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DEH84_RS01195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DEH84_RS01300	COG2922	Belongs to the Smg family
DEH84_RS01320	COG0126	phosphoglycerate kinase activity
DEH84_RS01340	COG2267	carboxylic ester hydrolase activity
DEH84_RS01355	COG0596	Alpha beta hydrolase
DEH84_RS01365	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DEH84_RS01375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DEH84_RS01385	COG1333	cytochrome c biogenesis protein
DEH84_RS01390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DEH84_RS01445	COG4970	Tfp pilus assembly protein FimT
DEH84_RS01490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DEH84_RS01495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DEH84_RS01500	COG0009	L-threonylcarbamoyladenylate synthase
DEH84_RS01520	COG1214	PFAM Peptidase M22, glycoprotease
DEH84_RS01530	COG1573	uracil-dna glycosylase
DEH84_RS01535	COG0598	Magnesium transport protein CorA
DEH84_RS01545	COG1981	membrane
DEH84_RS01565	COG1686	Belongs to the peptidase S11 family
DEH84_RS01570	COG2921	Belongs to the UPF0250 family
DEH84_RS01575	COG1862	Preprotein translocase
DEH84_RS01580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEH84_RS01585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEH84_RS01595	COG2119	membrane
DEH84_RS01605	COG0501	Belongs to the peptidase M48B family
DEH84_RS01610	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEH84_RS01615	COG0242	peptide deformylase activity
DEH84_RS01620	COG1652	LysM domain
DEH84_RS01625	COG0758	DNA mediated transformation
DEH84_RS01630	COG0321	lipoyl(octanoyl) transferase activity
DEH84_RS01635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DEH84_RS01655	COG1309	transcriptional regulator
DEH84_RS01670	COG0318	PFAM AMP-dependent synthetase and ligase
DEH84_RS01700	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS01725	COG3540	Alkaline phosphatase
DEH84_RS01745	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS01750	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEH84_RS01750	COG1024	Enoyl-CoA hydratase
DEH84_RS01755	COG0183	Belongs to the thiolase family
DEH84_RS01765	COG1024	Enoyl-CoA hydratase
DEH84_RS01770	COG2199	diguanylate cyclase activity
DEH84_RS01785	COG5265	(ABC) transporter
DEH84_RS01795	COG0330	HflC and HflK could
DEH84_RS01800	COG0418	dihydroorotase activity
DEH84_RS01815	COG4232	protein-disulfide reductase activity
DEH84_RS01820	COG2814	Major facilitator Superfamily
DEH84_RS01835	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DEH84_RS01845	COG4966	pilus assembly protein PilW
DEH84_RS01865	COG4251	negative regulation of phosphorylation
DEH84_RS01870	COG0138	bifunctional purine biosynthesis protein purh
DEH84_RS01875	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DEH84_RS01885	COG3047	cAMP biosynthetic process
DEH84_RS01890	COG1238	metal cluster binding
DEH84_RS01900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEH84_RS01915	COG1309	transcriptional regulator
DEH84_RS01930	COG0494	nUDIX hydrolase
DEH84_RS01940	COG1024	Enoyl-CoA hydratase
DEH84_RS01970	COG3128	pkhd-type hydroxylase
DEH84_RS01985	COG0861	Integral membrane protein TerC family
DEH84_RS02000	COG4783	chaperone-mediated protein folding
DEH84_RS02005	COG0315	cyclic pyranopterin monophosphate synthase activity
DEH84_RS02010	COG3307	-O-antigen
DEH84_RS02015	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DEH84_RS02025	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DEH84_RS02030	COG0735	belongs to the Fur family
DEH84_RS02035	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEH84_RS02040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DEH84_RS02055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEH84_RS02070	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DEH84_RS02085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEH84_RS02100	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEH84_RS02135	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS02140	COG1024	Enoyl-CoA hydratase
DEH84_RS02140	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEH84_RS02145	COG0183	Belongs to the thiolase family
DEH84_RS02150	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS02160	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS02165	COG0318	PFAM AMP-dependent synthetase and ligase
DEH84_RS02205	COG0121	glutamine amidotransferase
DEH84_RS02210	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS02225	COG1024	Enoyl-CoA hydratase
DEH84_RS02230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEH84_RS02255	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DEH84_RS02260	COG0514	ATP-dependent DNA helicase (RecQ)
DEH84_RS02270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DEH84_RS02280	COG2813	Specifically methylates the guanine in position
DEH84_RS02280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEH84_RS02285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEH84_RS02290	COG0069	glutamate synthase activity
DEH84_RS02295	COG0625	glutathione transferase activity
DEH84_RS02310	COG0284	orotidine-5'-phosphate decarboxylase activity
DEH84_RS02315	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEH84_RS02340	COG1410	methionine synthase
DEH84_RS02340	COG0646	methionine synthase
DEH84_RS02350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEH84_RS02355	COG2137	regulation of response to DNA damage stimulus
DEH84_RS02360	COG0045	succinate-CoA ligase (ADP-forming) activity
DEH84_RS02365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DEH84_RS02370	COG0861	Integral membrane protein TerC family
DEH84_RS02375	COG0515	serine threonine protein kinase
DEH84_RS02375	COG2815	serine threonine protein kinase
DEH84_RS02380	COG0631	protein serine/threonine phosphatase activity
DEH84_RS02390	COG1234	tRNA 3'-trailer cleavage
DEH84_RS02395	COG4969	Belongs to the N-Me-Phe pilin family
DEH84_RS02415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DEH84_RS02420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DEH84_RS02430	COG1404	Belongs to the peptidase S8 family
DEH84_RS02440	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DEH84_RS02440	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DEH84_RS02455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DEH84_RS02460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DEH84_RS02465	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DEH84_RS02505	COG0840	transmembrane signaling receptor activity
DEH84_RS02520	COG3012	SEC-C Motif Domain Protein
DEH84_RS02520	COG3318	Belongs to the UPF0149 family
DEH84_RS02525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEH84_RS02540	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DEH84_RS02565	COG0037	tRNA processing
DEH84_RS02575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEH84_RS02580	COG0484	heat shock protein binding
DEH84_RS02585	COG1522	sequence-specific DNA binding
DEH84_RS02600	COG4628	conserved protein (DUF2132)
DEH84_RS02605	COG2267	carboxylic ester hydrolase activity
DEH84_RS02610	COG5006	permease, DMT superfamily
DEH84_RS02615	COG2223	nitrite transmembrane transporter activity
DEH84_RS02625	COG4221	oxidoreductase activity
DEH84_RS02665	COG2124	cytochrome p450
DEH84_RS02685	COG1454	alcohol dehydrogenase
DEH84_RS02695	COG1042	CoA-binding domain protein
DEH84_RS02695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEH84_RS02695	COG0045	succinate-CoA ligase (ADP-forming) activity
DEH84_RS02710	COG0513	Belongs to the DEAD box helicase family
DEH84_RS02715	COG2814	Major facilitator Superfamily
DEH84_RS02725	COG0346	lactoylglutathione lyase activity
DEH84_RS02735	COG4948	Mandelate Racemase Muconate Lactonizing
DEH84_RS02760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEH84_RS02780	COG0625	glutathione transferase activity
DEH84_RS02785	COG1086	Polysaccharide biosynthesis protein
DEH84_RS02790	COG2205	protein histidine kinase activity
DEH84_RS02790	COG0784	Response regulator, receiver
DEH84_RS02795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEH84_RS02800	COG0793	Belongs to the peptidase S41A family
DEH84_RS02805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DEH84_RS02810	COG1611	Belongs to the LOG family
DEH84_RS02820	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DEH84_RS02825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DEH84_RS02835	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DEH84_RS02845	COG0494	nUDIX hydrolase
DEH84_RS02850	COG0442	prolyl-tRNA aminoacylation
DEH84_RS02855	COG0741	lytic transglycosylase activity
DEH84_RS02865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DEH84_RS02875	COG2890	protein-(glutamine-N5) methyltransferase activity
DEH84_RS02880	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEH84_RS02885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DEH84_RS02895	COG0602	queuosine metabolic process
DEH84_RS02900	COG0720	synthase
DEH84_RS02910	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DEH84_RS02940	COG3842	ATPase activity
DEH84_RS02945	COG1178	ABC-type Fe3 transport system permease component
DEH84_RS02950	COG1840	ABC-type Fe3 transport system, periplasmic component
DEH84_RS02955	COG0156	8-amino-7-oxononanoate synthase activity
DEH84_RS02965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEH84_RS02975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEH84_RS02980	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DEH84_RS02995	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
DEH84_RS03005	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DEH84_RS03010	COG0298	carbon dioxide binding
DEH84_RS03015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEH84_RS03020	COG1773	rubredoxin
DEH84_RS03025	COG1773	rubredoxin
DEH84_RS03030	COG1773	rubredoxin
DEH84_RS03035	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DEH84_RS03040	COG0375	protein maturation
DEH84_RS03045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DEH84_RS03055	COG0298	carbon dioxide binding
DEH84_RS03060	COG0409	Hydrogenase expression formation protein
DEH84_RS03065	COG0309	Hydrogenase expression formation protein (HypE)
DEH84_RS03070	COG2204	response regulator
DEH84_RS03090	COG1346	cytolysis
DEH84_RS03095	COG1380	Effector of murein hydrolase LrgA
DEH84_RS03100	COG5001	Diguanylate cyclase
DEH84_RS03100	COG2203	Gaf domain
DEH84_RS03100	COG3706	GGDEF domain
DEH84_RS03100	COG4251	negative regulation of phosphorylation
DEH84_RS03120	COG0326	Molecular chaperone. Has ATPase activity
DEH84_RS03135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEH84_RS03140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DEH84_RS03145	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEH84_RS03160	COG0316	Belongs to the HesB IscA family
DEH84_RS03165	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DEH84_RS03175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DEH84_RS03195	COG0259	pyridoxamine-phosphate oxidase activity
DEH84_RS03200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEH84_RS03210	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DEH84_RS03215	COG0741	lytic transglycosylase activity
DEH84_RS03220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEH84_RS03225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEH84_RS03265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DEH84_RS03265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DEH84_RS03280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DEH84_RS03285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEH84_RS03290	COG0515	serine threonine protein kinase
DEH84_RS03290	COG2815	serine threonine protein kinase
DEH84_RS03300	COG0248	Ppx GppA phosphatase
DEH84_RS03320	COG1722	exodeoxyribonuclease VII activity
DEH84_RS03325	COG0142	geranyltranstransferase activity
DEH84_RS03330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEH84_RS03345	COG0165	Argininosuccinate lyase
DEH84_RS03350	COG3275	phosphorelay sensor kinase activity
DEH84_RS03360	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DEH84_RS03365	COG0745	RESPONSE REGULATOR receiver
DEH84_RS03370	COG1360	Flagellar Motor Protein
DEH84_RS03395	COG1017	nitric oxide dioxygenase activity
DEH84_RS03395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEH84_RS03405	COG0069	glutamate synthase activity
DEH84_RS03405	COG0070	glutamate synthase
DEH84_RS03405	COG0067	glutamate synthase
DEH84_RS03415	COG1127	ABC transporter
DEH84_RS03420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DEH84_RS03425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DEH84_RS03430	COG2853	Lipoprotein
DEH84_RS03445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DEH84_RS03450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEH84_RS03455	COG0166	Belongs to the GPI family
DEH84_RS03475	COG1247	-acetyltransferase
DEH84_RS03485	COG2951	lytic endotransglycosylase activity
DEH84_RS03505	COG0431	NADPH-dependent FMN reductase
DEH84_RS03515	COG2205	protein histidine kinase activity
DEH84_RS03525	COG0840	transmembrane signaling receptor activity
DEH84_RS03530	COG0436	Aminotransferase
DEH84_RS03540	COG1739	Uncharacterized protein family UPF0029
DEH84_RS03575	COG0671	phosphoesterase, PA-phosphatase related
DEH84_RS03585	COG0297	glycogen (starch) synthase activity
DEH84_RS03590	COG0859	PFAM glycosyl transferase family 9
DEH84_RS03595	COG0859	PFAM glycosyl transferase family 9
DEH84_RS03605	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DEH84_RS03610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEH84_RS03615	COG3546	catalase activity
DEH84_RS03625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEH84_RS03640	COG2192	nodulation
DEH84_RS03655	COG0438	transferase activity, transferring glycosyl groups
DEH84_RS03665	COG0514	ATP-dependent DNA helicase (RecQ)
DEH84_RS03685	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS03695	COG2204	response regulator
DEH84_RS03705	COG0745	RESPONSE REGULATOR receiver
DEH84_RS03730	COG2205	protein histidine kinase activity
DEH84_RS03750	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DEH84_RS03775	COG0438	transferase activity, transferring glycosyl groups
DEH84_RS03785	COG1295	ribonuclease BN
DEH84_RS03790	COG0628	permease
DEH84_RS03815	COG0784	Response regulator, receiver
DEH84_RS03815	COG2205	protein histidine kinase activity
DEH84_RS03825	COG0114	fumarate hydratase activity
DEH84_RS03835	COG0438	transferase activity, transferring glycosyl groups
DEH84_RS03845	COG0517	IMP dehydrogenase activity
DEH84_RS03855	COG0784	Response regulator, receiver
DEH84_RS03855	COG2205	protein histidine kinase activity
DEH84_RS03865	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DEH84_RS03870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DEH84_RS03900	COG5265	(ABC) transporter
DEH84_RS03915	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DEH84_RS03960	COG0280	phosphate acetyltransferase
DEH84_RS03960	COG0281	malic enzyme
DEH84_RS03965	COG5001	Diguanylate cyclase
DEH84_RS03965	COG3300	MHYT domain
DEH84_RS03970	COG1596	polysaccharide export
DEH84_RS03975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DEH84_RS03975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEH84_RS03990	COG0840	transmembrane signaling receptor activity
DEH84_RS03995	COG0387	Pfam Sodium calcium exchanger
DEH84_RS04005	COG3647	Membrane
DEH84_RS04010	COG2733	membrane
DEH84_RS04055	COG0745	RESPONSE REGULATOR receiver
DEH84_RS04065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DEH84_RS04085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEH84_RS04090	COG1278	Cold shock
DEH84_RS04110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEH84_RS04145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DEH84_RS04165	COG2354	Protein conserved in bacteria
DEH84_RS04170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEH84_RS04170	COG2205	protein histidine kinase activity
DEH84_RS04180	COG0489	protein tyrosine kinase activity
DEH84_RS04180	COG2151	metal-sulfur cluster biosynthetic enzyme
DEH84_RS04185	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DEH84_RS04195	COG0850	regulation of cytokinetic process
DEH84_RS04235	COG1132	(ABC) transporter
DEH84_RS04250	COG0204	Acyl-transferase
DEH84_RS04265	COG0318	PFAM AMP-dependent synthetase and ligase
DEH84_RS04275	COG0318	PFAM AMP-dependent synthetase and ligase
DEH84_RS04295	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEH84_RS04320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEH84_RS04320	COG0543	2 iron, 2 sulfur cluster binding
DEH84_RS04335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DEH84_RS04345	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DEH84_RS04370	COG2878	Part of a membrane complex involved in electron transport
DEH84_RS04395	COG1785	Belongs to the alkaline phosphatase family
DEH84_RS04420	COG0625	glutathione transferase activity
DEH84_RS04445	COG0556	nucleotide-excision repair
DEH84_RS04475	COG1959	2 iron, 2 sulfur cluster binding
DEH84_RS04480	COG1104	cysteine desulfurase activity
DEH84_RS04485	COG0822	iron-sulfur transferase activity
DEH84_RS04490	COG0316	Belongs to the HesB IscA family
DEH84_RS04500	COG0443	Heat shock 70 kDa protein
DEH84_RS04525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DEH84_RS04560	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DEH84_RS04565	COG1074	ATP-dependent DNA helicase activity
DEH84_RS04570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DEH84_RS04575	COG1040	competence protein
DEH84_RS04580	COG2226	methyltransferase
DEH84_RS04600	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DEH84_RS04630	COG1612	heme a metabolic process
DEH84_RS04635	COG0109	protoheme IX farnesyltransferase activity
DEH84_RS04640	COG1999	signal sequence binding
DEH84_RS04665	COG0302	gtp cyclohydrolase
DEH84_RS04670	COG1793	dna ligase
DEH84_RS04730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEH84_RS04750	COG0343	queuine tRNA-ribosyltransferase activity
DEH84_RS04760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DEH84_RS04770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DEH84_RS04785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DEH84_RS04795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEH84_RS04795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEH84_RS04800	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DEH84_RS04840	COG2205	protein histidine kinase activity
DEH84_RS04845	COG0824	Thioesterase
DEH84_RS04855	COG0848	biopolymer transport protein
DEH84_RS04865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DEH84_RS04870	COG2766	serine protein kinase
DEH84_RS04875	COG2718	Belongs to the UPF0229 family
DEH84_RS04880	COG2719	SpoVR family
DEH84_RS04890	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DEH84_RS04895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DEH84_RS04910	COG1191	sigma factor activity
DEH84_RS04920	COG0840	transmembrane signaling receptor activity
DEH84_RS04925	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEH84_RS04930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEH84_RS04940	COG0268	Binds directly to 16S ribosomal RNA
DEH84_RS04945	COG0728	peptidoglycan biosynthetic process
DEH84_RS04955	COG1607	acyl-coa hydrolase
DEH84_RS04960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEH84_RS04965	COG0477	Major facilitator Superfamily
DEH84_RS04975	COG0433	COG0433 Predicted ATPase
DEH84_RS04980	COG0217	transcriptional regulatory protein
DEH84_RS04985	COG0151	Belongs to the GarS family
DEH84_RS04990	COG0408	coproporphyrinogen oxidase activity
DEH84_RS04995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEH84_RS05000	COG0799	negative regulation of ribosome biogenesis
DEH84_RS05005	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DEH84_RS05015	COG0424	maF-like protein
DEH84_RS05020	COG0702	epimerase
DEH84_RS05030	COG0823	Involved in the tonB-independent uptake of proteins
DEH84_RS05045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DEH84_RS05070	COG0784	Response regulator, receiver
DEH84_RS05070	COG2205	protein histidine kinase activity
DEH84_RS05070	COG5002	protein histidine kinase activity
DEH84_RS05080	COG2095	MarC family integral membrane protein
DEH84_RS05095	COG1126	abc transporter atp-binding protein
DEH84_RS05100	COG0765	amino acid transport
DEH84_RS05105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEH84_RS05115	COG2423	ornithine cyclodeaminase activity
DEH84_RS05120	COG1522	sequence-specific DNA binding
DEH84_RS05150	COG1132	(ABC) transporter
DEH84_RS05155	COG0189	ligase activity
DEH84_RS05155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEH84_RS05160	COG0189	ligase activity
DEH84_RS05160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEH84_RS05170	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DEH84_RS05210	COG1473	amidohydrolase
DEH84_RS05225	COG1131	(ABC) transporter
DEH84_RS05230	COG0842	Transport permease protein
DEH84_RS05240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEH84_RS05245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DEH84_RS05255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEH84_RS05260	COG0131	Imidazoleglycerol-phosphate dehydratase
DEH84_RS05270	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DEH84_RS05275	COG0107	imidazoleglycerol-phosphate synthase activity
DEH84_RS05285	COG2205	protein histidine kinase activity
DEH84_RS05295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEH84_RS05300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEH84_RS05305	COG0805	protein transport
DEH84_RS05310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEH84_RS05315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEH84_RS05320	COG0140	phosphoribosyl-ATP diphosphatase activity
DEH84_RS05325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DEH84_RS05330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DEH84_RS05340	COG0723	plastoquinol--plastocyanin reductase activity
DEH84_RS05345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DEH84_RS05350	COG2857	Cytochrome c1
DEH84_RS05355	COG0625	glutathione transferase activity
DEH84_RS05360	COG2969	positive regulation of protein catabolic process
DEH84_RS05375	COG1538	Outer membrane efflux protein
DEH84_RS05380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEH84_RS05385	COG1309	transcriptional regulator
DEH84_RS05390	COG0123	including yeast histone deacetylase and acetoin utilization protein
DEH84_RS05395	COG0824	Thioesterase
DEH84_RS05450	COG1522	sequence-specific DNA binding
DEH84_RS05465	COG0535	radical SAM domain protein
DEH84_RS05470	COG2010	Cytochrome c
DEH84_RS05475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEH84_RS05505	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEH84_RS05505	COG1024	Enoyl-CoA hydratase
DEH84_RS05510	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS05520	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS05530	COG2130	NADP-dependent
DEH84_RS05540	COG1660	Displays ATPase and GTPase activities
DEH84_RS05545	COG0497	DNA recombination
DEH84_RS05550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEH84_RS05555	COG1420	regulation of RNA biosynthetic process
DEH84_RS05575	COG0840	transmembrane signaling receptor activity
DEH84_RS05580	COG4206	TonB-dependent receptor
DEH84_RS05595	COG0625	glutathione transferase activity
DEH84_RS05600	COG0625	glutathione transferase activity
DEH84_RS05605	COG1294	oxidase, subunit
DEH84_RS05610	COG1271	oxidase subunit
DEH84_RS05635	COG2192	nodulation
DEH84_RS05640	COG1404	Belongs to the peptidase S8 family
DEH84_RS05665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DEH84_RS05670	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DEH84_RS05675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DEH84_RS05690	COG1706	bacterial-type flagellum-dependent cell motility
DEH84_RS05695	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DEH84_RS05700	COG4786	Flagellar basal body rod
DEH84_RS05715	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DEH84_RS05720	COG1558	bacterial-type flagellum-dependent cell motility
DEH84_RS05725	COG1815	bacterial-type flagellum-dependent cell motility
DEH84_RS05745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DEH84_RS05770	COG1136	(ABC) transporter
DEH84_RS05775	COG0084	hydrolase, TatD family'
DEH84_RS05795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DEH84_RS05805	COG2197	response regulator
DEH84_RS05810	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DEH84_RS05815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEH84_RS05825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEH84_RS05835	COG4974	Belongs to the 'phage' integrase family
DEH84_RS05855	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DEH84_RS05875	COG4263	nitrous-oxide reductase activity
DEH84_RS05885	COG1477	protein flavinylation
DEH84_RS05895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEH84_RS05895	COG1017	nitric oxide dioxygenase activity
DEH84_RS05900	COG1959	2 iron, 2 sulfur cluster binding
DEH84_RS05905	COG2833	Protein of unknown function (DUF455)
DEH84_RS05910	COG1968	undecaprenyl-diphosphatase activity
DEH84_RS05915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEH84_RS05920	COG2917	probably involved in intracellular septation
DEH84_RS05925	COG0271	Belongs to the BolA IbaG family
DEH84_RS05930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DEH84_RS05935	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DEH84_RS05950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEH84_RS05975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DEH84_RS05980	COG0756	dUTP diphosphatase activity
DEH84_RS05985	COG1047	Peptidyl-prolyl cis-trans
DEH84_RS05990	COG2850	peptidyl-arginine hydroxylation
DEH84_RS06005	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DEH84_RS06010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEH84_RS06025	COG1766	The M ring may be actively involved in energy transduction
DEH84_RS06035	COG1317	bacterial-type flagellum organization
DEH84_RS06040	COG1157	protein secretion by the type III secretion system
DEH84_RS06055	COG1580	Controls the rotational direction of flagella during chemotaxis
DEH84_RS06075	COG1338	Plays a role in the flagellum-specific transport system
DEH84_RS06100	COG0840	transmembrane signaling receptor activity
DEH84_RS06110	COG2199	diguanylate cyclase activity
DEH84_RS06110	COG2200	EAL domain
DEH84_RS06115	COG3046	protein related to deoxyribodipyrimidine photolyase
DEH84_RS06120	COG0415	Belongs to the DNA photolyase family
DEH84_RS06130	COG0415	Belongs to the DNA photolyase family
DEH84_RS06150	COG2815	serine threonine protein kinase
DEH84_RS06150	COG0515	serine threonine protein kinase
DEH84_RS06160	COG0840	transmembrane signaling receptor activity
DEH84_RS06180	COG1368	sulfuric ester hydrolase activity
DEH84_RS06185	COG0745	RESPONSE REGULATOR receiver
DEH84_RS06190	COG0642	Histidine kinase
DEH84_RS06195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DEH84_RS06200	COG0830	nickel cation binding
DEH84_RS06205	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DEH84_RS06210	COG0804	urea catabolic process
DEH84_RS06215	COG0832	Belongs to the urease beta subunit family
DEH84_RS06225	COG0831	urea catabolic process
DEH84_RS06230	COG2205	protein histidine kinase activity
DEH84_RS06230	COG5002	protein histidine kinase activity
DEH84_RS06230	COG0784	Response regulator, receiver
DEH84_RS06240	COG0494	nUDIX hydrolase
DEH84_RS06245	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DEH84_RS06250	COG0840	transmembrane signaling receptor activity
DEH84_RS06300	COG2863	cytochrome
DEH84_RS06305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEH84_RS06320	COG0729	surface antigen
DEH84_RS06345	COG0640	Transcriptional regulator
DEH84_RS06350	COG0659	secondary active sulfate transmembrane transporter activity
DEH84_RS06360	COG1937	Protein conserved in bacteria
DEH84_RS06370	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
DEH84_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS06415	COG4654	Cytochrome c, class I
DEH84_RS06440	COG0492	ferredoxin-NADP+ reductase activity
DEH84_RS06445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DEH84_RS06450	COG1648	precorrin-2 dehydrogenase activity
DEH84_RS06450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEH84_RS06455	COG2895	sulfate adenylyltransferase (ATP) activity
DEH84_RS06460	COG0175	sulfate reduction
DEH84_RS06465	COG0175	sulfate reduction
DEH84_RS06480	COG0730	response to heat
DEH84_RS06485	COG1752	Esterase of the alpha-beta hydrolase superfamily
DEH84_RS06495	COG2217	Heavy metal translocating P-type atpase
DEH84_RS06505	COG3278	Belongs to the heme-copper respiratory oxidase family
DEH84_RS06540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEH84_RS06545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DEH84_RS06560	COG1278	Cold shock
DEH84_RS06565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DEH84_RS06570	COG0542	response to heat
DEH84_RS06575	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DEH84_RS06600	COG0215	cysteine-tRNA ligase activity
DEH84_RS06610	COG0825	malonyl-CoA metabolic process
DEH84_RS06615	COG0037	tRNA processing
DEH84_RS06620	COG0527	aspartate kinase activity
DEH84_RS06630	COG2974	May be involved in recombination
DEH84_RS06635	COG0596	Alpha beta hydrolase
DEH84_RS06650	COG1619	proteins homologs of microcin C7 resistance protein MccF
DEH84_RS06665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEH84_RS06670	COG4172	Belongs to the ABC transporter superfamily
DEH84_RS06685	COG0779	Required for maturation of 30S ribosomal subunits
DEH84_RS06690	COG2251	uridine kinase activity
DEH84_RS06690	COG0195	Participates in both transcription termination and antitermination
DEH84_RS06695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DEH84_RS06700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEH84_RS06705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEH84_RS06720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEH84_RS06725	COG5001	Diguanylate cyclase
DEH84_RS06725	COG4251	negative regulation of phosphorylation
DEH84_RS06725	COG2203	Gaf domain
DEH84_RS06725	COG3706	GGDEF domain
DEH84_RS06730	COG2203	Gaf domain
DEH84_RS06730	COG4251	negative regulation of phosphorylation
DEH84_RS06730	COG5001	Diguanylate cyclase
DEH84_RS06730	COG3706	GGDEF domain
DEH84_RS06735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEH84_RS06760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEH84_RS06765	COG0776	regulation of translation
DEH84_RS06775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DEH84_RS06950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DEH84_RS07110	COG3179	chitinase
DEH84_RS07140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DEH84_RS07145	COG2010	Cytochrome c
DEH84_RS07145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DEH84_RS07180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEH84_RS07200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEH84_RS07215	COG0688	phosphatidylethanolamine metabolic process
DEH84_RS07230	COG1054	Belongs to the UPF0176 family
DEH84_RS07255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEH84_RS07270	COG2186	Transcriptional regulator
DEH84_RS07290	COG0840	transmembrane signaling receptor activity
DEH84_RS07300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEH84_RS07315	COG0402	S-adenosylhomocysteine deaminase activity
DEH84_RS07320	COG3845	ABC transporter
DEH84_RS07325	COG4603	Belongs to the binding-protein-dependent transport system permease family
DEH84_RS07345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEH84_RS07355	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DEH84_RS07365	COG0840	transmembrane signaling receptor activity
DEH84_RS07370	COG0012	GTP binding
DEH84_RS07375	COG2205	protein histidine kinase activity
DEH84_RS07375	COG0784	Response regulator, receiver
DEH84_RS07375	COG2198	Histidine kinase
DEH84_RS07380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEH84_RS07385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DEH84_RS07405	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DEH84_RS07410	COG0424	maF-like protein
DEH84_RS07415	COG1399	metal-binding, possibly nucleic acid-binding protein
DEH84_RS07420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DEH84_RS07425	COG0416	fatty acid biosynthetic process
DEH84_RS07430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEH84_RS07440	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS07445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEH84_RS07450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEH84_RS07465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEH84_RS07470	COG0481	GTPase activity
DEH84_RS07475	COG0681	Belongs to the peptidase S26 family
DEH84_RS07485	COG0571	ribonuclease III activity
DEH84_RS07490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEH84_RS07495	COG1381	Involved in DNA repair and RecF pathway recombination
DEH84_RS07505	COG0736	holo-[acyl-carrier-protein] synthase activity
DEH84_RS07510	COG1472	Belongs to the glycosyl hydrolase 3 family
DEH84_RS07520	COG1530	ribonuclease E activity
DEH84_RS07555	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DEH84_RS07560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DEH84_RS07565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DEH84_RS07580	COG0523	cobalamin synthesis protein
DEH84_RS07590	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DEH84_RS07595	COG0752	glycyl-tRNA synthetase alpha subunit
DEH84_RS07600	COG0751	glycine-tRNA ligase activity
DEH84_RS07605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DEH84_RS07620	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DEH84_RS07635	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEH84_RS07640	COG1187	pseudouridine synthase activity
DEH84_RS07650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DEH84_RS07665	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DEH84_RS07670	COG0124	histidyl-tRNA synthetase
DEH84_RS07685	COG1160	GTP binding
DEH84_RS07690	COG1923	regulation of RNA biosynthetic process
DEH84_RS07695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEH84_RS07700	COG0330	HflC and HflK could
DEH84_RS07705	COG0330	HflC and HflK could
DEH84_RS07715	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DEH84_RS07720	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEH84_RS07725	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DEH84_RS07740	COG0557	exoribonuclease II activity
DEH84_RS07745	COG0052	Belongs to the universal ribosomal protein uS2 family
DEH84_RS07750	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEH84_RS07755	COG0528	UMP kinase activity
DEH84_RS07760	COG0233	cytoplasmic translational termination
DEH84_RS07765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEH84_RS07775	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DEH84_RS07780	COG0750	zinc metalloprotease
DEH84_RS07795	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DEH84_RS07800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DEH84_RS07805	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DEH84_RS07810	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DEH84_RS07815	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEH84_RS07820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEH84_RS07830	COG0670	Belongs to the BI1 family
DEH84_RS07835	COG0305	Participates in initiation and elongation during chromosome replication
DEH84_RS07840	COG0359	binds to the 23S rRNA
DEH84_RS07845	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEH84_RS07850	COG2965	DNA replication, synthesis of RNA primer
DEH84_RS07855	COG0360	Binds together with S18 to 16S ribosomal RNA
DEH84_RS07860	COG1125	glycine betaine transport
DEH84_RS07860	COG0517	IMP dehydrogenase activity
DEH84_RS07870	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DEH84_RS07880	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEH84_RS07880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEH84_RS07890	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DEH84_RS07940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEH84_RS07975	COG0626	cystathionine gamma-synthase activity
DEH84_RS07980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DEH84_RS08010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DEH84_RS08010	COG0519	Catalyzes the synthesis of GMP from XMP
DEH84_RS08015	COG0582	viral genome integration into host DNA
DEH84_RS08035	COG3039	Transposase
DEH84_RS08175	COG0789	Transcriptional regulator
DEH84_RS08185	COG3039	Transposase
DEH84_RS08200	COG1815	bacterial-type flagellum-dependent cell motility
DEH84_RS08260	COG1368	sulfuric ester hydrolase activity
DEH84_RS08290	COG1742	UPF0060 membrane protein
DEH84_RS08385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEH84_RS08430	COG2132	Multicopper oxidase
DEH84_RS08450	COG5002	protein histidine kinase activity
DEH84_RS08480	COG2217	Heavy metal translocating P-type atpase
DEH84_RS08485	COG2217	Heavy metal translocating P-type atpase
DEH84_RS08495	COG3174	membrane
DEH84_RS08510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH84_RS08520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEH84_RS08560	COG5002	protein histidine kinase activity
DEH84_RS08575	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DEH84_RS08580	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DEH84_RS08585	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DEH84_RS08590	COG0598	Magnesium transport protein CorA
DEH84_RS08595	COG2205	protein histidine kinase activity
DEH84_RS08600	COG0745	RESPONSE REGULATOR receiver
DEH84_RS08640	COG2003	Belongs to the UPF0758 family
DEH84_RS08675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DEH84_RS08705	COG1475	DNA binding
DEH84_RS08725	COG0515	serine threonine protein kinase
DEH84_RS08760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEH84_RS08785	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DEH84_RS08790	COG4133	protoheme IX ABC transporter activity
DEH84_RS08795	COG3005	denitrification pathway
DEH84_RS08800	COG3043	anaerobic respiration
DEH84_RS08810	COG3062	negative regulation of establishment of protein localization
DEH84_RS08815	COG4459	periplasmic nitrate reductase
DEH84_RS08845	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS08870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DEH84_RS08880	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DEH84_RS08895	COG0563	adenylate kinase activity
DEH84_RS08900	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DEH84_RS08905	COG2835	tetraacyldisaccharide 4'-kinase activity
DEH84_RS08910	COG1663	tetraacyldisaccharide 4'-kinase activity
DEH84_RS08915	COG0848	biopolymer transport protein
DEH84_RS08920	COG0811	peptide transport
DEH84_RS08925	COG1570	exodeoxyribonuclease VII activity
DEH84_RS08930	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DEH84_RS08935	COG0567	Dehydrogenase, E1 component
DEH84_RS08940	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEH84_RS08945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEH84_RS08950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DEH84_RS08955	COG0631	protein serine/threonine phosphatase activity
DEH84_RS08965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DEH84_RS08970	COG0024	Methionine aminopeptidase
DEH84_RS08975	COG0047	phosphoribosylformylglycinamidine synthase activity
DEH84_RS08975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEH84_RS08995	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DEH84_RS09015	COG3851	Histidine kinase
DEH84_RS09020	COG0826	peptidase U32
DEH84_RS09030	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DEH84_RS09045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEH84_RS09050	COG4566	intracellular signal transduction
DEH84_RS09065	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEH84_RS09070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEH84_RS09090	COG0789	Transcriptional regulator
DEH84_RS09095	COG0587	DNA-directed DNA polymerase activity
DEH84_RS09110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEH84_RS09110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEH84_RS09120	COG5001	Diguanylate cyclase
DEH84_RS09120	COG4251	negative regulation of phosphorylation
DEH84_RS09120	COG3706	GGDEF domain
DEH84_RS09120	COG2203	Gaf domain
DEH84_RS09125	COG4251	negative regulation of phosphorylation
DEH84_RS09125	COG5001	Diguanylate cyclase
DEH84_RS09125	COG2203	Gaf domain
DEH84_RS09125	COG3706	GGDEF domain
DEH84_RS09130	COG1686	Belongs to the peptidase S11 family
DEH84_RS09140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEH84_RS09155	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEH84_RS09160	COG0366	Alpha amylase catalytic
DEH84_RS09165	COG0366	Alpha amylase catalytic
DEH84_RS09180	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEH84_RS09185	COG1640	4-alpha-glucanotransferase
DEH84_RS09190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DEH84_RS09195	COG1127	ABC transporter
DEH84_RS09200	COG3008	intermembrane lipid transfer
DEH84_RS09200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DEH84_RS09230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEH84_RS09235	COG4597	amino acid ABC transporter
DEH84_RS09240	COG0765	amino acid transport
DEH84_RS09245	COG5001	Diguanylate cyclase
DEH84_RS09245	COG3300	MHYT domain
DEH84_RS09255	COG0084	hydrolase, TatD family'
DEH84_RS09270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEH84_RS09275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DEH84_RS09280	COG0354	folic acid binding
DEH84_RS09300	COG0318	PFAM AMP-dependent synthetase and ligase
DEH84_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS09330	COG1253	flavin adenine dinucleotide binding
DEH84_RS09340	COG2183	response to ionizing radiation
DEH84_RS09345	COG0167	dihydroorotate dehydrogenase activity
DEH84_RS09350	COG0515	serine threonine protein kinase
DEH84_RS09360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DEH84_RS09365	COG0254	rRNA binding
DEH84_RS09380	COG0745	RESPONSE REGULATOR receiver
DEH84_RS09390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DEH84_RS09395	COG0581	inorganic phosphate transmembrane transporter activity
DEH84_RS09400	COG0573	inorganic phosphate transmembrane transporter activity
DEH84_RS09405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DEH84_RS09415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEH84_RS09425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEH84_RS09430	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DEH84_RS09435	COG1534	Rna-binding protein
DEH84_RS09445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEH84_RS09450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DEH84_RS09455	COG0505	Belongs to the CarA family
DEH84_RS09475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEH84_RS09480	COG2814	Major facilitator Superfamily
DEH84_RS09490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEH84_RS09495	COG4181	ATPase activity
DEH84_RS09520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEH84_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS09535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEH84_RS09535	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DEH84_RS09545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEH84_RS09550	COG0443	Heat shock 70 kDa protein
DEH84_RS09555	COG0484	heat shock protein binding
DEH84_RS09590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEH84_RS09600	COG1196	nuclear chromosome segregation
DEH84_RS09605	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DEH84_RS09625	COG0436	Aminotransferase
DEH84_RS09630	COG2171	N-acyltransferase activity
DEH84_RS09640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEH84_RS09645	COG2890	protein-(glutamine-N5) methyltransferase activity
DEH84_RS09650	COG0488	(ABC) transporter
DEH84_RS09660	COG1846	Transcriptional regulator
DEH84_RS09665	COG1764	response to oxidative stress
DEH84_RS09670	COG0791	NLP P60 protein
DEH84_RS09675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DEH84_RS09680	COG0746	molybdenum cofactor guanylyltransferase activity
DEH84_RS09690	COG0328	RNA-DNA hybrid ribonuclease activity
DEH84_RS09695	COG2226	methyltransferase
DEH84_RS09700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEH84_RS09705	COG0741	lytic transglycosylase activity
DEH84_RS09705	COG1388	LysM domain
DEH84_RS09710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEH84_RS09715	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEH84_RS09720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEH84_RS09725	COG0513	Belongs to the DEAD box helicase family
DEH84_RS09735	COG3022	response to hydroperoxide
DEH84_RS09745	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DEH84_RS09750	COG0564	pseudouridine synthase activity
DEH84_RS09765	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DEH84_RS09770	COG0148	phosphopyruvate hydratase activity
DEH84_RS09775	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DEH84_RS09780	COG0504	CTP synthase activity
DEH84_RS09795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DEH84_RS09800	COG0483	inositol monophosphate 1-phosphatase activity
DEH84_RS09810	COG1045	serine acetyltransferase
DEH84_RS09815	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS09835	COG0521	Mo-molybdopterin cofactor biosynthetic process
DEH84_RS09840	COG3028	Belongs to the UPF0307 family
DEH84_RS09845	COG0312	modulator of DNA gyrase
DEH84_RS09850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DEH84_RS09880	COG1610	YqeY-like protein
DEH84_RS09885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DEH84_RS09890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DEH84_RS09895	COG0617	tRNA 3'-terminal CCA addition
DEH84_RS09905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DEH84_RS09910	COG0628	permease
DEH84_RS09930	COG0009	L-threonylcarbamoyladenylate synthase
DEH84_RS09935	COG0613	PHP domain protein
DEH84_RS09945	COG0717	Belongs to the dCTP deaminase family
DEH84_RS09950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEH84_RS09955	COG0243	molybdopterin cofactor binding
DEH84_RS09960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DEH84_RS09965	COG0697	spore germination
DEH84_RS09975	COG0667	Aldo Keto reductase
DEH84_RS09980	COG2918	glutathione biosynthetic process
DEH84_RS09985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEH84_RS09990	COG3781	membrane
DEH84_RS10005	COG5001	Diguanylate cyclase
DEH84_RS10010	COG2197	response regulator
DEH84_RS10020	COG0251	oxidation-reduction process
DEH84_RS10035	COG1902	pentaerythritol trinitrate reductase activity
DEH84_RS10070	COG0829	nickel cation binding
DEH84_RS10080	COG2205	protein histidine kinase activity
DEH84_RS10080	COG0784	Response regulator, receiver
DEH84_RS10090	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS10105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DEH84_RS10125	COG3510	cephalosporin hydroxylase
DEH84_RS10145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH84_RS10180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DEH84_RS10185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEH84_RS10190	COG0740	serine-type endopeptidase activity
DEH84_RS10195	COG0544	peptidyl-prolyl cis-trans isomerase activity
DEH84_RS10235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEH84_RS10240	COG1183	phosphatidylcholine synthase activity
DEH84_RS10245	COG3264	Mechanosensitive ion channel
DEH84_RS10245	COG1196	nuclear chromosome segregation
DEH84_RS10250	COG0123	including yeast histone deacetylase and acetoin utilization protein
DEH84_RS10255	COG0714	Associated with various cellular activities
DEH84_RS10270	COG2951	lytic endotransglycosylase activity
DEH84_RS10280	COG0612	Peptidase, M16
DEH84_RS10285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH84_RS10290	COG0842	Transport permease protein
DEH84_RS10290	COG1129	ABC transporter
DEH84_RS10295	COG0842	Transport permease protein
DEH84_RS10300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEH84_RS10320	COG3852	Histidine kinase
DEH84_RS10330	COG0174	glutamine synthetase
DEH84_RS10335	COG1058	Belongs to the CinA family
DEH84_RS10335	COG1546	Belongs to the CinA family
DEH84_RS10365	COG2081	HI0933 family
DEH84_RS10370	COG2226	methyltransferase
DEH84_RS10395	COG0776	regulation of translation
DEH84_RS10400	COG0072	phenylalanine-tRNA ligase activity
DEH84_RS10400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEH84_RS10405	COG1064	alcohol dehydrogenase
DEH84_RS10410	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DEH84_RS10415	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEH84_RS10420	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DEH84_RS10425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEH84_RS10430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEH84_RS10440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEH84_RS10455	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DEH84_RS10460	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DEH84_RS10480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DEH84_RS10480	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DEH84_RS10485	COG0004	ammonium transporteR
DEH84_RS10490	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DEH84_RS10490	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DEH84_RS10495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DEH84_RS10510	COG0560	Phosphoserine phosphatase
DEH84_RS10540	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DEH84_RS10550	COG0463	Glycosyl transferase, family 2
DEH84_RS10560	COG0671	phosphoesterase, PA-phosphatase related
DEH84_RS10565	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DEH84_RS10580	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DEH84_RS10590	COG2321	neutral zinc metallopeptidase
DEH84_RS10600	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DEH84_RS10605	COG0802	atpase or kinase
DEH84_RS10610	COG0860	N-Acetylmuramoyl-L-alanine amidase
DEH84_RS10615	COG0586	Pfam SNARE associated Golgi protein
DEH84_RS10620	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DEH84_RS10625	COG1187	pseudouridine synthase activity
DEH84_RS10630	COG2814	Major facilitator Superfamily
DEH84_RS10635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEH84_RS10645	COG2814	Major facilitator Superfamily
DEH84_RS10650	COG1566	PFAM secretion protein HlyD family protein
DEH84_RS10665	COG1132	(ABC) transporter
DEH84_RS10675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DEH84_RS10690	COG0784	Response regulator, receiver
DEH84_RS10690	COG2205	protein histidine kinase activity
DEH84_RS10705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEH84_RS10710	COG1309	transcriptional regulator
DEH84_RS10715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DEH84_RS10720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DEH84_RS10725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEH84_RS10730	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DEH84_RS10735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DEH84_RS10740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEH84_RS10745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEH84_RS10750	COG3485	protocatechuate 3,4-dioxygenase
DEH84_RS10755	COG3485	protocatechuate 3,4-dioxygenase
DEH84_RS10760	COG0583	DNA-binding transcription factor activity
DEH84_RS10765	COG1414	Transcriptional regulator
DEH84_RS10775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DEH84_RS10780	COG0183	Belongs to the thiolase family
DEH84_RS10800	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEH84_RS10815	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DEH84_RS10825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEH84_RS10830	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DEH84_RS10835	COG0193	aminoacyl-tRNA hydrolase activity
DEH84_RS10845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DEH84_RS10850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEH84_RS10870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DEH84_RS10930	COG0488	(ABC) transporter
DEH84_RS10955	COG1199	ATP-dependent helicase activity
DEH84_RS10960	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DEH84_RS10965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DEH84_RS10985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEH84_RS10985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEH84_RS10990	COG0489	protein tyrosine kinase activity
DEH84_RS11000	COG0784	Response regulator, receiver
DEH84_RS11005	COG4251	negative regulation of phosphorylation
DEH84_RS11025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DEH84_RS11025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DEH84_RS11040	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DEH84_RS11045	COG1253	flavin adenine dinucleotide binding
DEH84_RS11055	COG0395	ABC-type sugar transport system, permease component
DEH84_RS11060	COG1175	transmembrane transport
DEH84_RS11080	COG2333	competence protein COMEC
DEH84_RS11080	COG0658	competence protein
DEH84_RS11090	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DEH84_RS11105	COG0346	lactoylglutathione lyase activity
DEH84_RS11110	COG0840	transmembrane signaling receptor activity
DEH84_RS11115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEH84_RS11125	COG1295	ribonuclease BN
DEH84_RS11135	COG0277	FAD linked oxidase domain protein
DEH84_RS11155	COG0494	nUDIX hydrolase
DEH84_RS11165	COG1007	ATP synthesis coupled electron transport
DEH84_RS11180	COG0713	ATP synthesis coupled electron transport
DEH84_RS11190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEH84_RS11195	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEH84_RS11200	COG1034	ATP synthesis coupled electron transport
DEH84_RS11210	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DEH84_RS11215	COG0649	NAD binding
DEH84_RS11220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEH84_RS11225	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEH84_RS11230	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEH84_RS11245	COG0149	triose-phosphate isomerase activity
DEH84_RS11250	COG1185	polyribonucleotide nucleotidyltransferase activity
DEH84_RS11255	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DEH84_RS11260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEH84_RS11270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEH84_RS11275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEH84_RS11280	COG1116	anion transmembrane transporter activity
DEH84_RS11285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEH84_RS11310	COG0129	dihydroxy-acid dehydratase activity
DEH84_RS11320	COG4654	Cytochrome c, class I
DEH84_RS11330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEH84_RS11360	COG0542	response to heat
DEH84_RS11375	COG0314	molybdopterin synthase activity
DEH84_RS11380	COG0303	'Molybdopterin
DEH84_RS11400	COG0436	Aminotransferase
DEH84_RS11410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DEH84_RS11415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DEH84_RS11425	COG1309	transcriptional regulator
DEH84_RS11430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH84_RS11435	COG0842	Transport permease protein
DEH84_RS11435	COG1129	ABC transporter
DEH84_RS11440	COG0842	Transport permease protein
DEH84_RS11445	COG3243	poly(R)-hydroxyalkanoic acid synthase
DEH84_RS11460	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DEH84_RS11465	COG0440	acetolactate synthase activity
DEH84_RS11470	COG0028	Belongs to the TPP enzyme family
DEH84_RS11500	COG0347	Belongs to the P(II) protein family
DEH84_RS11505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEH84_RS11505	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEH84_RS11545	COG3945	hemerythrin HHE cation binding domain
DEH84_RS11560	COG0583	DNA-binding transcription factor activity
DEH84_RS11565	COG0625	glutathione transferase activity
DEH84_RS11575	COG0577	efflux transmembrane transporter activity
DEH84_RS11575	COG1136	(ABC) transporter
DEH84_RS11580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH84_RS11595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DEH84_RS11605	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS11610	COG0183	Belongs to the thiolase family
DEH84_RS11615	COG3243	poly(R)-hydroxyalkanoic acid synthase
DEH84_RS11630	COG3161	chorismate lyase activity
DEH84_RS11640	COG2274	protein secretion by the type I secretion system
DEH84_RS11645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH84_RS11680	COG1522	sequence-specific DNA binding
DEH84_RS11705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DEH84_RS11715	COG0795	lipopolysaccharide-transporting ATPase activity
DEH84_RS11725	COG0583	DNA-binding transcription factor activity
DEH84_RS11750	COG2217	Heavy metal translocating P-type atpase
DEH84_RS11760	COG0840	transmembrane signaling receptor activity
DEH84_RS11785	COG1643	Atp-dependent helicase
DEH84_RS11795	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DEH84_RS11795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEH84_RS11800	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DEH84_RS11815	COG2308	Evidence 4 Homologs of previously reported genes of
DEH84_RS11860	COG0837	glucose binding
DEH84_RS11870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DEH84_RS11880	COG0800	Aldolase
DEH84_RS11885	COG0837	glucose binding
DEH84_RS11885	COG1737	Transcriptional regulator
DEH84_RS11890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH84_RS11895	COG1136	(ABC) transporter
DEH84_RS11905	COG1136	(ABC) transporter
DEH84_RS11905	COG0577	efflux transmembrane transporter activity
DEH84_RS11930	COG3954	Phosphoribulokinase
DEH84_RS11935	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DEH84_RS11940	COG0464	growth
DEH84_RS11945	COG4451	ribulose bisphosphate carboxylase, small
DEH84_RS11950	COG1850	ribulose-bisphosphate carboxylase activity
DEH84_RS11955	COG0826	peptidase U32
DEH84_RS11960	COG0583	DNA-binding transcription factor activity
DEH84_RS11965	COG0535	radical SAM domain protein
DEH84_RS11980	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DEH84_RS12005	COG0183	Belongs to the thiolase family
DEH84_RS12020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEH84_RS12025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DEH84_RS12040	COG4654	Cytochrome c, class I
DEH84_RS12045	COG0671	phosphoesterase, PA-phosphatase related
DEH84_RS12060	COG3706	GGDEF domain
DEH84_RS12065	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DEH84_RS12070	COG0308	aminopeptidase N
DEH84_RS12095	COG2059	Chromate
DEH84_RS12125	COG2030	dehydratase
DEH84_RS12160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEH84_RS12185	COG0285	dihydrofolate synthase activity
DEH84_RS12190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DEH84_RS12195	COG0159	tryptophan synthase activity
DEH84_RS12200	COG0133	tryptophan synthase activity
DEH84_RS12205	COG0135	phosphoribosylanthranilate isomerase activity
DEH84_RS12210	COG0101	tRNA pseudouridine synthase activity
DEH84_RS12220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DEH84_RS12225	COG0473	3-isopropylmalate dehydrogenase activity
DEH84_RS12230	COG0066	3-isopropylmalate dehydratase activity
DEH84_RS12240	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DEH84_RS12245	COG0372	Belongs to the citrate synthase family
DEH84_RS12250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DEH84_RS12255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DEH84_RS12260	COG1053	succinate dehydrogenase
DEH84_RS12265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DEH84_RS12275	COG2188	Transcriptional regulator
DEH84_RS12280	COG0039	L-malate dehydrogenase activity
DEH84_RS12340	COG1049	propionate catabolic process, 2-methylcitrate cycle
DEH84_RS12355	COG1451	nucleotide metabolic process
DEH84_RS12360	COG2925	Exonuclease
DEH84_RS12370	COG3850	Histidine kinase
DEH84_RS12370	COG4999	Histidine kinase
DEH84_RS12370	COG2205	protein histidine kinase activity
DEH84_RS12370	COG3437	response regulator, receiver
DEH84_RS12375	COG0564	pseudouridine synthase activity
DEH84_RS12385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DEH84_RS12390	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEH84_RS12395	COG1393	Belongs to the ArsC family
DEH84_RS12405	COG1012	belongs to the aldehyde dehydrogenase family
DEH84_RS12415	COG3284	Transcriptional regulator
DEH84_RS12420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEH84_RS12425	COG0546	phosphoglycolate phosphatase activity
DEH84_RS12435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DEH84_RS12445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEH84_RS12455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DEH84_RS12475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DEH84_RS12490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH84_RS12505	COG0494	nUDIX hydrolase
DEH84_RS12515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DEH84_RS12520	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DEH84_RS12520	COG1793	dna ligase
DEH84_RS12530	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DEH84_RS12535	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DEH84_RS12540	COG1492	cobalamin metabolic process
DEH84_RS12550	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DEH84_RS12555	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DEH84_RS12565	COG1120	ATPase activity
DEH84_RS12570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEH84_RS12585	COG4206	TonB-dependent receptor
DEH84_RS12605	COG2084	Dehydrogenase
DEH84_RS12630	COG2094	Belongs to the DNA glycosylase MPG family
DEH84_RS12670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DEH84_RS12680	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
DEH84_RS12685	COG3259	Nickel-dependent hydrogenase
DEH84_RS12695	COG1024	Enoyl-CoA hydratase
DEH84_RS12700	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEH84_RS12700	COG1902	pentaerythritol trinitrate reductase activity
DEH84_RS12705	COG1695	Transcriptional regulator
DEH84_RS12780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DEH84_RS12785	COG0513	Belongs to the DEAD box helicase family
DEH84_RS12790	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DEH84_RS12795	COG1674	ftsk spoiiie
DEH84_RS12805	COG0492	ferredoxin-NADP+ reductase activity
DEH84_RS12810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEH84_RS12815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEH84_RS12820	COG0215	cysteine-tRNA ligase activity
DEH84_RS12845	COG0540	Belongs to the ATCase OTCase family
DEH84_RS12850	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEH84_RS12855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEH84_RS12860	COG1678	Uncharacterized ACR, COG1678
DEH84_RS12865	COG0415	Belongs to the DNA photolyase family
DEH84_RS12880	COG0840	transmembrane signaling receptor activity
DEH84_RS12910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DEH84_RS12915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DEH84_RS12920	COG0584	glycerophosphoryl diester phosphodiesterase
DEH84_RS12935	COG0835	chemotaxis
DEH84_RS12940	COG0643	Histidine kinase
DEH84_RS12940	COG2198	Histidine kinase
DEH84_RS12945	COG0745	RESPONSE REGULATOR receiver
DEH84_RS12955	COG3851	Histidine kinase
DEH84_RS12965	COG0783	Belongs to the Dps family
DEH84_RS12975	COG0210	DNA helicase
DEH84_RS12980	COG0516	GMP reductase activity
DEH84_RS12980	COG0517	IMP dehydrogenase activity
DEH84_RS13000	COG0589	response to stress
DEH84_RS13005	COG0525	valine-tRNA ligase activity
DEH84_RS13010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DEH84_RS13045	COG1965	Belongs to the frataxin family
DEH84_RS13070	COG2255	four-way junction helicase activity
DEH84_RS13075	COG0425	Belongs to the sulfur carrier protein TusA family
DEH84_RS13090	COG0402	S-adenosylhomocysteine deaminase activity
DEH84_RS13095	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEH84_RS13110	COG0697	spore germination
DEH84_RS13125	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEH84_RS13130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DEH84_RS13135	COG0196	riboflavin kinase activity
DEH84_RS13150	COG0252	asparaginase activity
DEH84_RS13160	COG0765	amino acid transport
DEH84_RS13165	COG0765	amino acid transport
DEH84_RS13170	COG1126	abc transporter atp-binding protein
DEH84_RS13175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DEH84_RS13180	COG4191	Histidine kinase
DEH84_RS13195	COG1666	GTP binding
DEH84_RS13200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DEH84_RS13205	COG3123	guanosine phosphorylase activity
DEH84_RS13210	COG0137	argininosuccinate synthase activity
DEH84_RS13230	COG0784	Response regulator, receiver
DEH84_RS13230	COG4191	Histidine kinase
DEH84_RS13235	COG0318	PFAM AMP-dependent synthetase and ligase
DEH84_RS13245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEH84_RS13250	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS13270	COG0657	acetylesterase activity
DEH84_RS13280	COG2267	carboxylic ester hydrolase activity
DEH84_RS13295	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DEH84_RS13300	COG1741	Belongs to the pirin family
DEH84_RS13305	COG0583	DNA-binding transcription factor activity
DEH84_RS13310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEH84_RS13320	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DEH84_RS13325	COG0501	Belongs to the peptidase M48B family
DEH84_RS13330	COG2154	pterin-4-alpha-carbinolamine dehydratase
DEH84_RS13335	COG1162	GTPase activity
DEH84_RS13350	COG0494	nUDIX hydrolase
DEH84_RS13355	COG0335	large ribosomal subunit rRNA binding
DEH84_RS13360	COG0336	Belongs to the RNA methyltransferase TrmD family
DEH84_RS13365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEH84_RS13370	COG0228	four-way junction DNA binding
DEH84_RS13380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DEH84_RS13385	COG2900	Belongs to the SlyX family
DEH84_RS13395	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DEH84_RS13400	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DEH84_RS13410	COG0463	Glycosyl transferase, family 2
DEH84_RS13410	COG0457	Tetratricopeptide repeat
DEH84_RS13425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DEH84_RS13445	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DEH84_RS13450	COG0181	hydroxymethylbilane synthase activity
DEH84_RS13460	COG2959	enzyme of heme biosynthesis
DEH84_RS13490	COG5002	protein histidine kinase activity
DEH84_RS13495	COG0745	RESPONSE REGULATOR receiver
DEH84_RS13515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEH84_RS13520	COG1758	RNA polymerase activity
DEH84_RS13525	COG0194	GDP metabolic process
DEH84_RS13530	COG1561	YicC-like family, N-terminal region
DEH84_RS13545	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DEH84_RS13550	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEH84_RS13555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DEH84_RS13560	COG0318	PFAM AMP-dependent synthetase and ligase
DEH84_RS13590	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DEH84_RS13600	COG0287	Prephenate dehydrogenase
DEH84_RS13605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DEH84_RS13625	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DEH84_RS13630	COG2847	Copper chaperone PCu(A)C
DEH84_RS13645	COG0004	ammonium transporteR
DEH84_RS13655	COG3158	transport of potassium into the cell
DEH84_RS13660	COG3135	benzoate transporter
DEH84_RS13665	COG0189	ligase activity
DEH84_RS13670	COG0745	RESPONSE REGULATOR receiver
DEH84_RS13680	COG0488	(ABC) transporter
DEH84_RS13685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEH84_RS13705	COG5000	phosphorelay sensor kinase activity
DEH84_RS13710	COG2204	response regulator
DEH84_RS13725	COG0859	PFAM glycosyl transferase family 9
DEH84_RS13745	COG1442	glycosyl transferase family 8
DEH84_RS13745	COG1216	Glycosyl transferase, family 2
DEH84_RS13775	COG0859	PFAM glycosyl transferase family 9
DEH84_RS13780	COG1132	(ABC) transporter
DEH84_RS13795	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DEH84_RS13805	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DEH84_RS13810	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DEH84_RS13815	COG1201	RNA secondary structure unwinding
DEH84_RS13820	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEH84_RS13830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEH84_RS13865	COG1215	transferase activity, transferring glycosyl groups
DEH84_RS13880	COG1773	rubredoxin
DEH84_RS13895	COG0739	heme binding
DEH84_RS13920	COG0653	protein targeting
DEH84_RS13945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEH84_RS13950	COG3384	dioxygenase
DEH84_RS13955	COG0683	leucine binding
DEH84_RS13960	COG5002	protein histidine kinase activity
DEH84_RS13965	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS13970	COG0840	transmembrane signaling receptor activity
DEH84_RS13980	COG0142	geranyltranstransferase activity
DEH84_RS13985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEH84_RS13995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DEH84_RS14020	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DEH84_RS14025	COG1704	LemA family
DEH84_RS14045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEH84_RS14075	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DEH84_RS14150	COG1216	Glycosyl transferase, family 2
DEH84_RS14155	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DEH84_RS14160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEH84_RS14170	COG0489	protein tyrosine kinase activity
DEH84_RS14205	COG0463	Glycosyl transferase, family 2
DEH84_RS14210	COG0297	glycogen (starch) synthase activity
DEH84_RS14285	COG0438	transferase activity, transferring glycosyl groups
DEH84_RS14290	COG1088	dTDP-glucose 4,6-dehydratase activity
DEH84_RS14295	COG1091	dTDP-4-dehydrorhamnose reductase activity
DEH84_RS14310	COG0463	Glycosyl transferase, family 2
DEH84_RS14320	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEH84_RS14330	COG0297	glycogen (starch) synthase activity
DEH84_RS14365	COG2244	polysaccharide biosynthetic process
DEH84_RS14395	COG1215	transferase activity, transferring glycosyl groups
DEH84_RS14400	COG1088	dTDP-glucose 4,6-dehydratase activity
DEH84_RS14405	COG1091	dTDP-4-dehydrorhamnose reductase activity
DEH84_RS14425	COG0546	phosphoglycolate phosphatase activity
DEH84_RS14425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DEH84_RS14435	COG0300	oxidoreductase activity
DEH84_RS14450	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS14465	COG0183	Belongs to the thiolase family
DEH84_RS14470	COG1024	Enoyl-CoA hydratase
DEH84_RS14475	COG1024	Enoyl-CoA hydratase
DEH84_RS14480	COG2814	Major facilitator Superfamily
DEH84_RS14490	COG2272	Belongs to the type-B carboxylesterase lipase family
DEH84_RS14500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEH84_RS14525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEH84_RS14530	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DEH84_RS14535	COG1047	Peptidyl-prolyl cis-trans
DEH84_RS14540	COG2003	Belongs to the UPF0758 family
DEH84_RS14560	COG3706	GGDEF domain
DEH84_RS14565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DEH84_RS14570	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DEH84_RS14575	COG2201	protein-glutamate methylesterase activity
DEH84_RS14580	COG1752	Esterase of the alpha-beta hydrolase superfamily
DEH84_RS14590	COG0459	protein refolding
DEH84_RS14595	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DEH84_RS14600	COG0583	DNA-binding transcription factor activity
DEH84_RS14605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DEH84_RS14610	COG4208	sulfate ABC transporter
DEH84_RS14615	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DEH84_RS14620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DEH84_RS14645	COG4235	cytochrome complex assembly
DEH84_RS14650	COG3088	subunit of a heme lyase
DEH84_RS14665	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DEH84_RS14675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DEH84_RS14685	COG4133	protoheme IX ABC transporter activity
DEH84_RS14715	COG2863	cytochrome
DEH84_RS14755	COG1116	anion transmembrane transporter activity
DEH84_RS14770	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DEH84_RS14775	COG3829	transcription factor binding
DEH84_RS14790	COG0450	alkyl hydroperoxide reductase
DEH84_RS14795	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS14815	COG3267	Type II secretory pathway component ExeA
DEH84_RS14815	COG3409	Peptidoglycan-binding domain 1 protein
DEH84_RS14825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEH84_RS14830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEH84_RS14840	COG0438	transferase activity, transferring glycosyl groups
DEH84_RS14855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DEH84_RS14865	COG3383	formate dehydrogenase (NAD+) activity
DEH84_RS14875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEH84_RS14880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DEH84_RS14885	COG0511	ligase activity, forming carbon-carbon bonds
DEH84_RS14890	COG0439	Biotin carboxylase
DEH84_RS14895	COG2264	protein methyltransferase activity
DEH84_RS14905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEH84_RS14915	COG0588	phosphoglycerate mutase activity
DEH84_RS14925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DEH84_RS14930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DEH84_RS14935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DEH84_RS14950	COG0386	Belongs to the glutathione peroxidase family
DEH84_RS14955	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DEH84_RS14970	COG2943	transferase activity, transferring hexosyl groups
DEH84_RS14975	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DEH84_RS15030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEH84_RS15040	COG0583	DNA-binding transcription factor activity
DEH84_RS15045	COG3135	benzoate transporter
DEH84_RS15050	COG0583	DNA-binding transcription factor activity
DEH84_RS15060	COG4638	Rieske (2fe-2S)
DEH84_RS15065	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DEH84_RS15080	COG2814	Major facilitator Superfamily
DEH84_RS15090	COG0776	regulation of translation
DEH84_RS15095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEH84_RS15110	COG1414	Transcriptional regulator
DEH84_RS15120	COG0203	ribosomal protein L17
DEH84_RS15125	COG0202	RNA polymerase activity
DEH84_RS15130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEH84_RS15135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEH84_RS15140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEH84_RS15145	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DEH84_RS15150	COG0201	protein transport
DEH84_RS15155	COG0200	Binds to the 23S rRNA
DEH84_RS15160	COG1841	ribosomal large subunit assembly
DEH84_RS15165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEH84_RS15170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DEH84_RS15175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEH84_RS15180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEH84_RS15185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEH84_RS15190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEH84_RS15195	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEH84_RS15200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEH84_RS15205	COG0312	modulator of DNA gyrase
DEH84_RS15215	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEH84_RS15220	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEH84_RS15225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DEH84_RS15230	COG0792	nuclease activity
DEH84_RS15240	COG2823	Periplasmic or secreted lipoprotein
DEH84_RS15245	COG2084	Dehydrogenase
DEH84_RS15270	COG2197	response regulator
DEH84_RS15285	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DEH84_RS15295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEH84_RS15300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH84_RS15320	COG3150	esterase
DEH84_RS15325	COG0557	exoribonuclease II activity
DEH84_RS15335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEH84_RS15340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEH84_RS15345	COG0513	Belongs to the DEAD box helicase family
DEH84_RS15355	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DEH84_RS15360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DEH84_RS15365	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DEH84_RS15375	COG0617	tRNA 3'-terminal CCA addition
DEH84_RS15380	COG0840	transmembrane signaling receptor activity
DEH84_RS15395	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DEH84_RS15400	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEH84_RS15405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DEH84_RS15410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEH84_RS15420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEH84_RS15425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEH84_RS15430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DEH84_RS15435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEH84_RS15445	COG3116	cell division
DEH84_RS15450	COG0275	rRNA processing
DEH84_RS15455	COG2001	Belongs to the MraZ family
DEH84_RS15480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DEH84_RS15500	COG0351	phosphomethylpyrimidine kinase
DEH84_RS15510	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DEH84_RS15535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DEH84_RS15545	COG1136	(ABC) transporter
DEH84_RS15550	COG4591	ABC-type transport system involved in lipoprotein release permease component
DEH84_RS15570	COG0400	carboxylic ester hydrolase activity
DEH84_RS15580	COG0463	Glycosyl transferase, family 2
DEH84_RS15600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH84_RS15605	COG0583	DNA-binding transcription factor activity
DEH84_RS15620	COG0410	ABC transporter
DEH84_RS15635	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEH84_RS15650	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS15655	COG1024	Enoyl-CoA hydratase
DEH84_RS15660	COG0318	PFAM AMP-dependent synthetase and ligase
DEH84_RS15670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DEH84_RS15675	COG1028	Short-chain dehydrogenase reductase Sdr
DEH84_RS15680	COG1846	Transcriptional regulator
DEH84_RS15685	COG0583	DNA-binding transcription factor activity
DEH84_RS15690	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEH84_RS15690	COG1024	Enoyl-CoA hydratase
DEH84_RS15695	COG0183	Belongs to the thiolase family
DEH84_RS15700	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS15710	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS15720	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS15730	COG0513	Belongs to the DEAD box helicase family
DEH84_RS15750	COG0861	Integral membrane protein TerC family
DEH84_RS15780	COG1196	nuclear chromosome segregation
DEH84_RS15790	COG1280	lysine exporter protein (LysE YggA)
DEH84_RS15805	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DEH84_RS15810	COG4149	molybdate abc transporter
DEH84_RS15820	COG2258	MOSC domain
DEH84_RS15835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DEH84_RS15840	COG3437	response regulator, receiver
DEH84_RS15840	COG4999	Histidine kinase
DEH84_RS15840	COG2205	protein histidine kinase activity
DEH84_RS15840	COG3850	Histidine kinase
DEH84_RS15890	COG2165	general secretion pathway protein
DEH84_RS15895	COG2165	general secretion pathway protein
DEH84_RS15910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DEH84_RS15915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DEH84_RS15920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DEH84_RS15925	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEH84_RS15930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEH84_RS15935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEH84_RS15940	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEH84_RS15950	COG0356	it plays a direct role in the translocation of protons across the membrane
DEH84_RS15980	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DEH84_RS15990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEH84_RS15995	COG0210	DNA helicase
DEH84_RS16000	COG1765	OsmC-like protein
DEH84_RS16005	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DEH84_RS16010	COG0772	Belongs to the SEDS family
DEH84_RS16015	COG0768	penicillin binding
DEH84_RS16020	COG2831	hemolysin activation secretion protein
DEH84_RS16045	COG1077	Cell shape determining protein MreB Mrl
DEH84_RS16050	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEH84_RS16055	COG0154	amidase activity
DEH84_RS16060	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEH84_RS16085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEH84_RS16095	COG0724	RNA recognition motif
DEH84_RS16100	COG0659	secondary active sulfate transmembrane transporter activity
DEH84_RS16140	COG2207	Transcriptional regulator
DEH84_RS16150	COG0492	ferredoxin-NADP+ reductase activity
DEH84_RS16155	COG0693	protein deglycase activity
DEH84_RS16165	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DEH84_RS16180	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DEH84_RS16185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEH84_RS16190	COG2146	nitrite reductase [NAD(P)H] activity
DEH84_RS16195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEH84_RS16200	COG3707	response regulator
DEH84_RS16205	COG2116	formate transmembrane transporter activity
DEH84_RS16210	COG0515	serine threonine protein kinase
DEH84_RS16215	COG5002	protein histidine kinase activity
DEH84_RS16215	COG3447	MASE1 domain protein
DEH84_RS16215	COG5001	Diguanylate cyclase
DEH84_RS16225	COG4085	toxin activity
DEH84_RS16225	COG1525	nuclease
DEH84_RS16225	COG0737	Belongs to the 5'-nucleotidase family
DEH84_RS16235	COG5507	3-demethylubiquinone-9 3-methyltransferase
DEH84_RS16245	COG2207	Transcriptional regulator
DEH84_RS16245	COG1609	Transcriptional regulator
DEH84_RS16250	COG2072	flavoprotein involved in K transport
DEH84_RS16255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEH84_RS16275	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DEH84_RS16340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEH84_RS16345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DEH84_RS16360	COG5002	protein histidine kinase activity
DEH84_RS16365	COG3177	Filamentation induced by cAMP protein fic
DEH84_RS16375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEH84_RS16385	COG0840	transmembrane signaling receptor activity
DEH84_RS16395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEH84_RS16405	COG2211	Major facilitator Superfamily
DEH84_RS16410	COG0840	transmembrane signaling receptor activity
DEH84_RS16415	COG3622	Belongs to the hyi family
DEH84_RS16420	COG0596	Alpha beta hydrolase
DEH84_RS16425	COG4681	YaeQ
DEH84_RS16430	COG0318	PFAM AMP-dependent synthetase and ligase
DEH84_RS16435	COG0840	transmembrane signaling receptor activity
DEH84_RS16445	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DEH84_RS16450	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DEH84_RS16455	COG2133	pyrroloquinoline quinone binding
DEH84_RS16465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEH84_RS16470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEH84_RS16475	COG2267	carboxylic ester hydrolase activity
DEH84_RS16485	COG0784	Response regulator, receiver
DEH84_RS16485	COG5002	protein histidine kinase activity
DEH84_RS16490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEH84_RS16500	COG3842	ATPase activity
DEH84_RS16510	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEH84_RS16515	COG1177	transmembrane transport
DEH84_RS16530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DEH84_RS16540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DEH84_RS16545	COG2866	Carboxypeptidase
DEH84_RS16550	COG0632	four-way junction helicase activity
DEH84_RS16555	COG2197	response regulator
DEH84_RS16560	COG4585	Histidine kinase
DEH84_RS16565	COG1702	phosphate starvation-inducible protein PhoH
DEH84_RS16570	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEH84_RS16585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEH84_RS16625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEH84_RS16640	COG0386	Belongs to the glutathione peroxidase family
DEH84_RS16660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEH84_RS16665	COG1024	Enoyl-CoA hydratase
DEH84_RS16665	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEH84_RS16670	COG0183	Belongs to the thiolase family
DEH84_RS16675	COG1960	acyl-CoA dehydrogenase activity
DEH84_RS16685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DEH84_RS16685	COG4651	solute:proton antiporter activity
DEH84_RS16705	COG3228	Belongs to the MtfA family
DEH84_RS16745	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DEH84_RS16760	COG0482	sulfurtransferase activity
DEH84_RS16785	COG1349	DNA-binding transcription factor activity
DEH84_RS16800	COG0625	glutathione transferase activity
DEH84_RS16805	COG0495	leucyl-tRNA aminoacylation
DEH84_RS16845	COG1012	belongs to the aldehyde dehydrogenase family
DEH84_RS16850	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
DEH84_RS16855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEH84_RS16860	COG0840	transmembrane signaling receptor activity
DEH84_RS16870	COG1177	transmembrane transport
DEH84_RS16875	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEH84_RS16880	COG3842	ATPase activity
DEH84_RS16885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DEH84_RS16890	COG0174	glutamine synthetase
DEH84_RS16935	COG2011	ABC-type metal ion transport system permease component
DEH84_RS16940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEH84_RS16950	COG2175	clavaminate synthase activity
DEH84_RS16965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEH84_RS16970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DEH84_RS16985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEH84_RS17025	COG3706	GGDEF domain
DEH84_RS17030	COG1950	PFAM Membrane protein of
DEH84_RS17035	COG1546	Belongs to the CinA family
DEH84_RS17040	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DEH84_RS17060	COG0281	malic enzyme
DEH84_RS17060	COG0280	phosphate acetyltransferase
DEH84_RS17075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEH84_RS17080	COG0741	lytic transglycosylase activity
DEH84_RS17085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEH84_RS17100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DEH84_RS17105	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DEH84_RS17110	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DEH84_RS17120	COG3447	MASE1 domain protein
DEH84_RS17120	COG5001	Diguanylate cyclase
DEH84_RS17120	COG5002	protein histidine kinase activity
DEH84_RS17125	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DEH84_RS17145	COG0840	transmembrane signaling receptor activity
DEH84_RS17150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEH84_RS17155	COG1560	Kdo2-lipid A biosynthetic process
DEH84_RS17160	COG1560	Kdo2-lipid A biosynthetic process
DEH84_RS17175	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEH84_RS17185	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DEH84_RS17190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DEH84_RS17210	COG2353	YceI-like domain
DEH84_RS17240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEH84_RS17250	COG1475	DNA binding
DEH84_RS17260	COG1192	Involved in chromosome partitioning
DEH84_RS17275	COG0357	Ribosomal RNA small subunit methyltransferase G
DEH84_RS17280	COG0445	tRNA wobble uridine modification
DEH84_RS17300	COG3012	SEC-C Motif Domain Protein
DEH84_RS17310	COG0724	RNA recognition motif
DEH84_RS17320	COG4221	oxidoreductase activity
DEH84_RS17330	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DEH84_RS17350	COG3437	response regulator, receiver
DEH84_RS17360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DEH84_RS17370	COG0706	membrane insertase activity
DEH84_RS17375	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DEH84_RS17385	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DEH84_RS17390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DEH84_RS17410	COG3284	Transcriptional regulator
DEH84_RS17415	COG0004	ammonium transporteR
DEH84_RS17425	COG0788	formyltetrahydrofolate deformylase activity
DEH84_RS17430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DEH84_RS17445	COG3850	Histidine kinase
DEH84_RS17450	COG2197	response regulator
DEH84_RS17475	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DEH84_RS17515	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DEH84_RS17545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEH84_RS17555	COG2076	Multidrug Resistance protein
DEH84_RS17615	COG2207	Transcriptional regulator
DEH84_RS17620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DEH84_RS17650	COG4115	mRNA cleavage
DEH84_RS17655	COG2161	toxin-antitoxin pair type II binding
DEH84_RS17680	COG3437	response regulator, receiver
DEH84_RS17710	COG0431	NADPH-dependent FMN reductase
DEH84_RS17715	COG1393	Belongs to the ArsC family
DEH84_RS17720	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DEH84_RS17735	COG1215	transferase activity, transferring glycosyl groups
DEH84_RS17740	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DEH84_RS17755	COG0243	molybdopterin cofactor binding
DEH84_RS17760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DEH84_RS17795	COG0697	spore germination
DEH84_RS17800	COG2818	Glycosylase
DEH84_RS17825	COG0724	RNA recognition motif
DEH84_RS17830	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEH84_RS17840	COG2201	protein-glutamate methylesterase activity
DEH84_RS17850	COG0584	glycerophosphoryl diester phosphodiesterase
DEH84_RS17855	COG2165	general secretion pathway protein
DEH84_RS17860	COG1459	type II secretion system
DEH84_RS17910	COG2197	response regulator
DEH84_RS17940	COG0811	peptide transport
DEH84_RS17970	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DEH84_RS17975	COG0628	permease
DEH84_RS18000	COG0574	Belongs to the PEP-utilizing enzyme family
DEH84_RS18000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEH84_RS18040	COG2186	Transcriptional regulator
DEH84_RS18050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DEH84_RS18055	COG0583	DNA-binding transcription factor activity
DEH84_RS18060	COG0247	lactate metabolic process
DEH84_RS18070	COG1139	Iron-sulfur cluster binding protein
DEH84_RS18080	COG1620	l-lactate permease
DEH84_RS18105	COG3851	Histidine kinase
DEH84_RS18125	COG2197	response regulator
DEH84_RS18135	COG3901	Regulator of nitric oxide reductase transcription
DEH84_RS18135	COG0348	domain, Protein
DEH84_RS18150	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DEH84_RS18155	COG1392	Phosphate transport regulator
DEH84_RS18160	COG0306	phosphate transporter
DEH84_RS18185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEH84_RS18190	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DEH84_RS18195	COG3437	response regulator, receiver
DEH84_RS18200	COG0784	Response regulator, receiver
DEH84_RS18200	COG2198	Histidine kinase
DEH84_RS18200	COG2205	protein histidine kinase activity
DEH84_RS18215	COG3850	Histidine kinase
DEH84_RS18220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DEH84_RS18225	COG2197	response regulator
DEH84_RS18235	COG2223	nitrite transmembrane transporter activity
DEH84_RS18240	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DEH84_RS18245	COG1140	nitrate reductase beta subunit
DEH84_RS18250	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DEH84_RS18255	COG2181	nitrate reductase activity
DEH84_RS18265	COG0288	reversible hydration of carbon dioxide
DEH84_RS18280	COG3154	lipid carrier protein
DEH84_RS18285	COG0826	peptidase U32
DEH84_RS18290	COG0826	peptidase U32
DEH84_RS18295	COG3550	peptidyl-serine autophosphorylation
DEH84_RS18310	COG0346	lactoylglutathione lyase activity
DEH84_RS18320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEH84_RS18325	COG0798	PFAM Bile acid sodium symporter
DEH84_RS18335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEH84_RS18350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEH84_RS18355	COG0612	Peptidase, M16
DEH84_RS18370	COG3604	Transcriptional regulator
DEH84_RS18385	COG2010	Cytochrome c
DEH84_RS18400	COG4548	von Willebrand factor, type A
DEH84_RS18405	COG2223	nitrite transmembrane transporter activity
DEH84_RS18420	COG1335	isochorismatase
DEH84_RS18445	COG1629	transport
DEH84_RS18455	COG4558	Periplasmic binding protein
DEH84_RS18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEH84_RS18465	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEH84_RS18475	COG1192	Involved in chromosome partitioning
DEH84_RS18495	COG2814	Major facilitator Superfamily
DEH84_RS18500	COG1725	Transcriptional regulator
DEH84_RS18505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEH84_RS18530	COG2144	transferase activity, transferring acyl groups
DEH84_RS18535	COG0438	transferase activity, transferring glycosyl groups
DEH84_RS18545	COG2072	flavoprotein involved in K transport
DEH84_RS18555	COG0348	domain, Protein
DEH84_RS18570	COG2186	Transcriptional regulator
DEH84_RS18605	COG1012	belongs to the aldehyde dehydrogenase family
DEH84_RS18610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEH84_RS18615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEH84_RS18620	COG2267	carboxylic ester hydrolase activity
DEH84_RS18630	COG0069	glutamate synthase activity
DEH84_RS18635	COG2218	PFAM glutamate synthase alpha subunit domain protein
DEH84_RS18640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DEH84_RS18665	COG0583	DNA-binding transcription factor activity
DEH84_RS18675	COG0347	Belongs to the P(II) protein family
DEH84_RS18680	COG0004	ammonium transporteR
DEH84_RS18695	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DEH84_RS18700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEH84_RS18705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEH84_RS18715	COG1053	succinate dehydrogenase
DEH84_RS18720	COG2188	Transcriptional regulator
DEH84_RS18770	COG0585	pseudouridine synthase activity
DEH84_RS18780	COG0318	PFAM AMP-dependent synthetase and ligase
DEH84_RS18800	COG0154	amidase activity
DEH84_RS18865	COG1113	amino acid transport
DEH84_RS18875	COG0840	transmembrane signaling receptor activity
DEH84_RS18890	COG0789	Transcriptional regulator
DEH84_RS18895	COG2608	mercury ion transmembrane transporter activity
DEH84_RS18900	COG2169	Transcriptional regulator
DEH84_RS18900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEH84_RS18925	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
DEH84_RS18930	COG1229	Formylmethanofuran dehydrogenase subunit A
DEH84_RS18995	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
DEH84_RS19005	COG0702	epimerase