locus-tag	class	description
BXU06_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BXU06_RS00010	COG0592	DNA-directed DNA polymerase activity
BXU06_RS00020	COG2337	Toxic component of a toxin-antitoxin (TA) module
BXU06_RS00035	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BXU06_RS00055	COG2959	enzyme of heme biosynthesis
BXU06_RS00065	COG0181	hydroxymethylbilane synthase activity
BXU06_RS00070	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BXU06_RS00080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BXU06_RS00085	COG2204	response regulator
BXU06_RS00090	COG5000	phosphorelay sensor kinase activity
BXU06_RS00100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXU06_RS00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BXU06_RS00110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXU06_RS00115	COG0840	transmembrane signaling receptor activity
BXU06_RS00120	COG0840	transmembrane signaling receptor activity
BXU06_RS00125	COG3217	Mosc domain protein beta barrel domain protein
BXU06_RS00125	COG0633	Ferredoxin
BXU06_RS00140	COG0840	transmembrane signaling receptor activity
BXU06_RS00155	COG1131	(ABC) transporter
BXU06_RS00160	COG0842	Transport permease protein
BXU06_RS00170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BXU06_RS00175	COG2353	YceI-like domain
BXU06_RS00180	COG2353	YceI-like domain
BXU06_RS00185	COG3038	cytochrome b561
BXU06_RS00190	COG3384	dioxygenase
BXU06_RS00195	COG0583	DNA-binding transcription factor activity
BXU06_RS00200	COG0625	glutathione transferase activity
BXU06_RS00215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BXU06_RS00220	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BXU06_RS00230	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BXU06_RS00235	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXU06_RS00240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXU06_RS00300	COG2815	serine threonine protein kinase
BXU06_RS00300	COG0515	serine threonine protein kinase
BXU06_RS00320	COG4659	FMN binding
BXU06_RS00325	COG4658	electron transport chain
BXU06_RS00330	COG4656	Part of a membrane complex involved in electron transport
BXU06_RS00335	COG2878	Part of a membrane complex involved in electron transport
BXU06_RS00340	COG4657	Part of a membrane complex involved in electron transport
BXU06_RS00360	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BXU06_RS00400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BXU06_RS00405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BXU06_RS00410	COG1127	ABC transporter
BXU06_RS00450	COG4681	YaeQ
BXU06_RS00465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BXU06_RS00545	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BXU06_RS00550	COG0583	DNA-binding transcription factor activity
BXU06_RS00555	COG0840	transmembrane signaling receptor activity
BXU06_RS00565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BXU06_RS00570	COG0675	Transposase, IS605 OrfB family
BXU06_RS00575	COG4521	taurine ABC transporter
BXU06_RS00580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BXU06_RS00585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_RS00590	COG2175	clavaminate synthase activity
BXU06_RS00605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BXU06_RS00610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BXU06_RS00620	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BXU06_RS00625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU06_RS00630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BXU06_RS00665	COG0405	Gamma-glutamyltransferase
BXU06_RS00670	COG0640	Transcriptional regulator
BXU06_RS00675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXU06_RS00680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXU06_RS00685	COG0798	PFAM Bile acid sodium symporter
BXU06_RS00705	COG0625	glutathione transferase activity
BXU06_RS00710	COG0583	DNA-binding transcription factor activity
BXU06_RS00720	COG3039	Transposase
BXU06_RS00735	COG0632	four-way junction helicase activity
BXU06_RS00740	COG0671	phosphoesterase, PA-phosphatase related
BXU06_RS00745	COG2255	four-way junction helicase activity
BXU06_RS00755	COG0210	DNA helicase
BXU06_RS00765	COG2841	Protein conserved in bacteria
BXU06_RS00770	COG1752	Esterase of the alpha-beta hydrolase superfamily
BXU06_RS00775	COG2226	methyltransferase
BXU06_RS00780	COG2267	carboxylic ester hydrolase activity
BXU06_RS00795	COG3039	Transposase
BXU06_RS00805	COG0583	DNA-binding transcription factor activity
BXU06_RS00815	COG2171	N-acyltransferase activity
BXU06_RS00825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BXU06_RS00875	COG2884	Cell division ATP-binding protein ftsE
BXU06_RS00885	COG0612	Peptidase, M16
BXU06_RS00890	COG0612	Peptidase, M16
BXU06_RS00895	COG0742	ribosomal rna small subunit methyltransferase
BXU06_RS00900	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BXU06_RS00920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BXU06_RS00940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BXU06_RS00945	COG0081	regulation of translation
BXU06_RS00950	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BXU06_RS00955	COG0222	ribosome binding
BXU06_RS00960	COG0085	RNA polymerase activity
BXU06_RS00965	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BXU06_RS00970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BXU06_RS00975	COG0049	tRNA binding
BXU06_RS00980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BXU06_RS00985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BXU06_RS00990	COG0051	transcription antitermination factor activity, RNA binding
BXU06_RS00995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BXU06_RS01000	COG0088	Forms part of the polypeptide exit tunnel
BXU06_RS01005	COG0089	rRNA binding
BXU06_RS01010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BXU06_RS01015	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BXU06_RS01020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BXU06_RS01025	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BXU06_RS01030	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BXU06_RS01035	COG0255	Belongs to the universal ribosomal protein uL29 family
BXU06_RS01040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BXU06_RS01045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BXU06_RS01050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BXU06_RS01055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BXU06_RS01060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BXU06_RS01065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BXU06_RS01070	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BXU06_RS01075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BXU06_RS01085	COG1841	ribosomal large subunit assembly
BXU06_RS01090	COG0200	Binds to the 23S rRNA
BXU06_RS01095	COG0201	protein transport
BXU06_RS01100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BXU06_RS01105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BXU06_RS01110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BXU06_RS01115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BXU06_RS01120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BXU06_RS01125	COG0202	RNA polymerase activity
BXU06_RS01130	COG0203	ribosomal protein L17
BXU06_RS01140	COG5001	Diguanylate cyclase
BXU06_RS01140	COG3300	MHYT domain
BXU06_RS01150	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BXU06_RS01155	COG4535	Mg2 and Co2 transporter CorC
BXU06_RS01160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BXU06_RS01165	COG1702	phosphate starvation-inducible protein PhoH
BXU06_RS01170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BXU06_RS01205	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_RS01220	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BXU06_RS01225	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU06_RS01235	COG0318	PFAM AMP-dependent synthetase and ligase
BXU06_RS01240	COG1960	acyl-CoA dehydrogenase activity
BXU06_RS01250	COG3162	membrane
BXU06_RS01255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXU06_RS01265	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU06_RS01280	COG2801	Transposase and inactivated derivatives
BXU06_RS01300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BXU06_RS01320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BXU06_RS01345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXU06_RS01350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXU06_RS01350	COG2813	Specifically methylates the guanine in position
BXU06_RS01355	COG2258	MOSC domain
BXU06_RS01360	COG0505	Belongs to the CarA family
BXU06_RS01365	COG1396	sequence-specific DNA binding
BXU06_RS01370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BXU06_RS01390	COG0784	Response regulator, receiver
BXU06_RS01390	COG4191	Histidine kinase
BXU06_RS01435	COG0583	DNA-binding transcription factor activity
BXU06_RS01445	COG0546	phosphoglycolate phosphatase activity
BXU06_RS01450	COG1942	4-Oxalocrotonate Tautomerase
BXU06_RS01455	COG0584	glycerophosphoryl diester phosphodiesterase
BXU06_RS01470	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_RS01475	COG1024	Enoyl-CoA hydratase
BXU06_RS01480	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXU06_RS01485	COG2050	protein possibly involved in aromatic compounds catabolism
BXU06_RS01495	COG0183	Belongs to the thiolase family
BXU06_RS01505	COG1024	Enoyl-CoA hydratase
BXU06_RS01520	COG0840	transmembrane signaling receptor activity
BXU06_RS01525	COG0179	Fumarylacetoacetate (FAA) hydrolase
BXU06_RS01535	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_RS01540	COG3384	dioxygenase
BXU06_RS01545	COG3384	dioxygenase
BXU06_RS01555	COG3971	2-oxopent-4-enoate hydratase activity
BXU06_RS01570	COG2814	Major facilitator Superfamily
BXU06_RS01585	COG0235	Class ii aldolase
BXU06_RS01595	COG0251	oxidation-reduction process
BXU06_RS01615	COG0613	PHP domain protein
BXU06_RS01620	COG0009	L-threonylcarbamoyladenylate synthase
BXU06_RS01625	COG1994	Peptidase M50
BXU06_RS01630	COG0180	Tryptophanyl-tRNA synthetase
BXU06_RS01645	COG3530	Putative quorum-sensing-regulated virulence factor
BXU06_RS01650	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BXU06_RS01675	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BXU06_RS01675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BXU06_RS01695	COG1660	Displays ATPase and GTPase activities
BXU06_RS01700	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BXU06_RS01710	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BXU06_RS01715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BXU06_RS01720	COG1137	ATPase activity
BXU06_RS01725	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BXU06_RS01735	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BXU06_RS01790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BXU06_RS01795	COG1968	undecaprenyl-diphosphatase activity
BXU06_RS01805	COG0010	Belongs to the arginase family
BXU06_RS01810	COG0347	Belongs to the P(II) protein family
BXU06_RS01815	COG0004	ammonium transporteR
BXU06_RS01820	COG0675	Transposase, IS605 OrfB family
BXU06_RS01825	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BXU06_RS01850	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXU06_RS01850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BXU06_RS01860	COG0174	glutamine synthetase
BXU06_RS01865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BXU06_RS01875	COG0069	glutamate synthase activity
BXU06_RS01880	COG1522	sequence-specific DNA binding
BXU06_RS01895	COG0693	protein deglycase activity
BXU06_RS01900	COG0840	transmembrane signaling receptor activity
BXU06_RS01905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BXU06_RS01915	COG1192	Involved in chromosome partitioning
BXU06_RS01925	COG0514	ATP-dependent DNA helicase (RecQ)
BXU06_RS01930	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BXU06_RS01965	COG0560	Phosphoserine phosphatase
BXU06_RS01970	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BXU06_RS01975	COG0602	queuosine metabolic process
BXU06_RS01980	COG0720	synthase
BXU06_RS01985	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BXU06_RS02000	COG3220	belongs to the UPF0276 family
BXU06_RS02010	COG3437	response regulator, receiver
BXU06_RS02010	COG2770	Histidine kinase
BXU06_RS02020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXU06_RS02025	COG1758	RNA polymerase activity
BXU06_RS02030	COG0194	GDP metabolic process
BXU06_RS02035	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BXU06_RS02040	COG0424	maF-like protein
BXU06_RS02050	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BXU06_RS02055	COG0416	fatty acid biosynthetic process
BXU06_RS02060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXU06_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_RS02075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXU06_RS02080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXU06_RS02085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BXU06_RS02100	COG0840	transmembrane signaling receptor activity
BXU06_RS02120	COG0174	glutamine synthetase
BXU06_RS02130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BXU06_RS02135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BXU06_RS02140	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BXU06_RS02150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BXU06_RS02150	COG0519	Catalyzes the synthesis of GMP from XMP
BXU06_RS02155	COG0210	DNA helicase
BXU06_RS02210	COG2814	Major facilitator Superfamily
BXU06_RS02215	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BXU06_RS02220	COG0179	Fumarylacetoacetate (FAA) hydrolase
BXU06_RS02240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BXU06_RS02245	COG2022	thiamine diphosphate biosynthetic process
BXU06_RS02270	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BXU06_RS02280	COG0121	glutamine amidotransferase
BXU06_RS02290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BXU06_RS02305	COG0360	Binds together with S18 to 16S ribosomal RNA
BXU06_RS02315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BXU06_RS02320	COG0359	binds to the 23S rRNA
BXU06_RS02325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BXU06_RS02330	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BXU06_RS02340	COG0084	hydrolase, TatD family'
BXU06_RS02345	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BXU06_RS02345	COG0321	lipoyl(octanoyl) transferase activity
BXU06_RS02360	COG0494	nUDIX hydrolase
BXU06_RS02365	COG0187	DNA topoisomerase II activity
BXU06_RS02370	COG2382	esterase
BXU06_RS02390	COG4771	TonB-dependent receptor
BXU06_RS02400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BXU06_RS02410	COG5433	transposase activity
BXU06_RS02420	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BXU06_RS02425	COG1140	nitrate reductase beta subunit
BXU06_RS02430	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BXU06_RS02435	COG2181	nitrate reductase activity
BXU06_RS02445	COG1196	nuclear chromosome segregation
BXU06_RS02455	COG2431	L-lysine efflux transmembrane transporter activity
BXU06_RS02485	COG0826	peptidase U32
BXU06_RS02490	COG0826	peptidase U32
BXU06_RS02495	COG3154	lipid carrier protein
BXU06_RS02520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU06_RS02525	COG1177	transmembrane transport
BXU06_RS02530	COG1176	ABC-type spermidine putrescine transport system, permease component I
BXU06_RS02535	COG3842	ATPase activity
BXU06_RS02550	COG0174	glutamine synthetase
BXU06_RS02555	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BXU06_RS02560	COG1396	sequence-specific DNA binding
BXU06_RS02560	COG1917	Cupin 2, conserved barrel domain protein
BXU06_RS02565	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_RS02575	COG0326	Molecular chaperone. Has ATPase activity
BXU06_RS02580	COG0697	spore germination
BXU06_RS02590	COG1414	Transcriptional regulator
BXU06_RS02615	COG4536	flavin adenine dinucleotide binding
BXU06_RS02625	COG0237	dephospho-CoA kinase activity
BXU06_RS02630	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BXU06_RS02635	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BXU06_RS02665	COG0559	Belongs to the binding-protein-dependent transport system permease family
BXU06_RS02680	COG0410	ABC transporter
BXU06_RS02685	COG0829	nickel cation binding
BXU06_RS02690	COG0831	urea catabolic process
BXU06_RS02695	COG0832	Belongs to the urease beta subunit family
BXU06_RS02700	COG0804	urea catabolic process
BXU06_RS02705	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BXU06_RS02710	COG0830	nickel cation binding
BXU06_RS02715	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BXU06_RS02725	COG2719	SpoVR family
BXU06_RS02730	COG2718	Belongs to the UPF0229 family
BXU06_RS02735	COG2766	serine protein kinase
BXU06_RS02740	COG1115	amino acid carrier protein
BXU06_RS02745	COG2205	protein histidine kinase activity
BXU06_RS02750	COG0745	RESPONSE REGULATOR receiver
BXU06_RS02755	COG0527	aspartate kinase activity
BXU06_RS02795	COG0840	transmembrane signaling receptor activity
BXU06_RS02800	COG0840	transmembrane signaling receptor activity
BXU06_RS02810	COG0675	Transposase, IS605 OrfB family
BXU06_RS02820	COG4771	TonB-dependent receptor
BXU06_RS02830	COG0348	domain, Protein
BXU06_RS02865	COG0675	Transposase, IS605 OrfB family
BXU06_RS02880	COG4774	siderophore transport
BXU06_RS02920	COG0577	efflux transmembrane transporter activity
BXU06_RS02920	COG1136	(ABC) transporter
BXU06_RS02925	COG1136	(ABC) transporter
BXU06_RS02925	COG0577	efflux transmembrane transporter activity
BXU06_RS02950	COG0583	DNA-binding transcription factor activity
BXU06_RS02960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXU06_RS02965	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BXU06_RS02970	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BXU06_RS02975	COG0316	Belongs to the HesB IscA family
BXU06_RS02980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BXU06_RS02985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU06_RS02990	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BXU06_RS03000	COG1280	lysine exporter protein (LysE YggA)
BXU06_RS03015	COG3038	cytochrome b561
BXU06_RS03020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU06_RS03025	COG2223	nitrite transmembrane transporter activity
BXU06_RS03035	COG1538	Outer membrane efflux protein
BXU06_RS03040	COG0577	efflux transmembrane transporter activity
BXU06_RS03040	COG1136	(ABC) transporter
BXU06_RS03045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXU06_RS03065	COG1960	acyl-CoA dehydrogenase activity
BXU06_RS03070	COG0183	Belongs to the thiolase family
BXU06_RS03075	COG0789	Transcriptional regulator
BXU06_RS03080	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXU06_RS03085	COG1022	Amp-dependent synthetase and ligase
BXU06_RS03135	COG1024	Enoyl-CoA hydratase
BXU06_RS03140	COG1024	Enoyl-CoA hydratase
BXU06_RS03150	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BXU06_RS03160	COG3706	GGDEF domain
BXU06_RS03165	COG0688	phosphatidylethanolamine metabolic process
BXU06_RS03170	COG0840	transmembrane signaling receptor activity
BXU06_RS03190	COG4657	Part of a membrane complex involved in electron transport
BXU06_RS03195	COG2878	Part of a membrane complex involved in electron transport
BXU06_RS03200	COG4656	Part of a membrane complex involved in electron transport
BXU06_RS03205	COG4658	electron transport chain
BXU06_RS03210	COG4659	FMN binding
BXU06_RS03220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BXU06_RS03225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXU06_RS03230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BXU06_RS03235	COG0497	DNA recombination
BXU06_RS03240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BXU06_RS03245	COG0784	Response regulator, receiver
BXU06_RS03245	COG2198	Histidine kinase
BXU06_RS03245	COG0643	Histidine kinase
BXU06_RS03250	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BXU06_RS03255	COG0745	RESPONSE REGULATOR receiver
BXU06_RS03260	COG0835	chemotaxis
BXU06_RS03260	COG0784	Response regulator, receiver
BXU06_RS03265	COG0784	Response regulator, receiver
BXU06_RS03265	COG0835	chemotaxis
BXU06_RS03280	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BXU06_RS03290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BXU06_RS03300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BXU06_RS03305	COG0277	FAD linked oxidase domain protein
BXU06_RS03310	COG0528	UMP kinase activity
BXU06_RS03315	COG0528	UMP kinase activity
BXU06_RS03320	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BXU06_RS03325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BXU06_RS03330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BXU06_RS03340	COG2197	response regulator
BXU06_RS03345	COG3850	Histidine kinase
BXU06_RS03350	COG0288	reversible hydration of carbon dioxide
BXU06_RS03355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BXU06_RS03370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BXU06_RS03385	COG1393	Belongs to the ArsC family
BXU06_RS03390	COG2223	nitrite transmembrane transporter activity
BXU06_RS03425	COG2974	May be involved in recombination
BXU06_RS03430	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BXU06_RS03440	COG0039	L-malate dehydrogenase activity
BXU06_RS03445	COG2188	Transcriptional regulator
BXU06_RS03450	COG2009	succinate dehydrogenase
BXU06_RS03460	COG1053	succinate dehydrogenase
BXU06_RS03465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BXU06_RS03470	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BXU06_RS03480	COG0567	Dehydrogenase, E1 component
BXU06_RS03485	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXU06_RS03490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXU06_RS03495	COG0045	succinate-CoA ligase (ADP-forming) activity
BXU06_RS03500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BXU06_RS03505	COG0675	Transposase, IS605 OrfB family
BXU06_RS03510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXU06_RS03525	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BXU06_RS03540	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BXU06_RS03560	COG0105	UTP biosynthetic process
BXU06_RS03565	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BXU06_RS03570	COG1426	Protein conserved in bacteria
BXU06_RS03575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BXU06_RS03580	COG0124	histidyl-tRNA synthetase
BXU06_RS03585	COG2976	Protein conserved in bacteria
BXU06_RS03590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXU06_RS03595	COG1160	GTP binding
BXU06_RS03600	COG1923	regulation of RNA biosynthetic process
BXU06_RS03605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BXU06_RS03610	COG0330	HflC and HflK could
BXU06_RS03615	COG0330	HflC and HflK could
BXU06_RS03620	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BXU06_RS03625	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BXU06_RS03645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_RS03650	COG0675	Transposase, IS605 OrfB family
BXU06_RS03660	COG3459	Glycosyltransferase 36 associated
BXU06_RS03665	COG0166	Belongs to the GPI family
BXU06_RS03670	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BXU06_RS03680	COG3237	CsbD-like
BXU06_RS03685	COG2823	Periplasmic or secreted lipoprotein
BXU06_RS03725	COG2308	Evidence 4 Homologs of previously reported genes of
BXU06_RS03740	COG2307	Protein conserved in bacteria
BXU06_RS03740	COG2308	Evidence 4 Homologs of previously reported genes of
BXU06_RS03745	COG1305	Transglutaminase-like
BXU06_RS03770	COG2217	Heavy metal translocating P-type atpase
BXU06_RS03780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BXU06_RS03805	COG0675	Transposase, IS605 OrfB family
BXU06_RS03815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BXU06_RS03845	COG1678	Uncharacterized ACR, COG1678
BXU06_RS03855	COG0675	Transposase, IS605 OrfB family
BXU06_RS03865	COG0675	Transposase, IS605 OrfB family
BXU06_RS03870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXU06_RS03885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BXU06_RS03905	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BXU06_RS03910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BXU06_RS03920	COG3039	Transposase
BXU06_RS03930	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BXU06_RS03930	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BXU06_RS03940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BXU06_RS03955	COG1846	Transcriptional regulator
BXU06_RS03960	COG0697	spore germination
BXU06_RS03965	COG2962	Rard protein
BXU06_RS03975	COG0166	Belongs to the GPI family
BXU06_RS03980	COG2267	carboxylic ester hydrolase activity
BXU06_RS04010	COG1944	ATP diphosphatase activity
BXU06_RS04015	COG0312	modulator of DNA gyrase
BXU06_RS04030	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BXU06_RS04040	COG0307	riboflavin synthase, alpha
BXU06_RS04045	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BXU06_RS04075	COG1733	regulation of RNA biosynthetic process
BXU06_RS04085	COG2169	Transcriptional regulator
BXU06_RS04085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BXU06_RS04090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BXU06_RS04100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXU06_RS04105	COG2188	Transcriptional regulator
BXU06_RS04110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BXU06_RS04115	COG5002	protein histidine kinase activity
BXU06_RS04115	COG5001	Diguanylate cyclase
BXU06_RS04115	COG3447	MASE1 domain protein
BXU06_RS04120	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BXU06_RS04120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BXU06_RS04145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BXU06_RS04150	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BXU06_RS04165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BXU06_RS04180	COG2866	Carboxypeptidase
BXU06_RS04205	COG1131	(ABC) transporter
BXU06_RS04225	COG2205	protein histidine kinase activity
BXU06_RS04225	COG0784	Response regulator, receiver
BXU06_RS04245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BXU06_RS04250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BXU06_RS04255	COG0586	Pfam SNARE associated Golgi protein
BXU06_RS04260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXU06_RS04265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXU06_RS04270	COG1862	Preprotein translocase
BXU06_RS04275	COG0343	queuine tRNA-ribosyltransferase activity
BXU06_RS04285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BXU06_RS04290	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BXU06_RS04295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BXU06_RS04300	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BXU06_RS04305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BXU06_RS04310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXU06_RS04310	COG0072	phenylalanine-tRNA ligase activity
BXU06_RS04315	COG0776	regulation of translation
BXU06_RS04340	COG0436	Aminotransferase
BXU06_RS04385	COG1857	crispr-associated protein
BXU06_RS04400	COG1518	maintenance of DNA repeat elements
BXU06_RS04405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BXU06_RS04420	COG0736	holo-[acyl-carrier-protein] synthase activity
BXU06_RS04425	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BXU06_RS04430	COG1381	Involved in DNA repair and RecF pathway recombination
BXU06_RS04435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BXU06_RS04440	COG0571	ribonuclease III activity
BXU06_RS04450	COG0481	GTPase activity
BXU06_RS04460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXU06_RS04485	COG3781	membrane
BXU06_RS04500	COG0544	peptidyl-prolyl cis-trans isomerase activity
BXU06_RS04505	COG0740	serine-type endopeptidase activity
BXU06_RS04510	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BXU06_RS04515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BXU06_RS04535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU06_RS04565	COG0583	DNA-binding transcription factor activity
BXU06_RS04575	COG0667	Aldo Keto reductase
BXU06_RS04595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BXU06_RS04595	COG4651	solute:proton antiporter activity
BXU06_RS04600	COG0018	arginyl-trna synthetase
BXU06_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_RS04625	COG0583	DNA-binding transcription factor activity
BXU06_RS04635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BXU06_RS04635	COG0047	phosphoribosylformylglycinamidine synthase activity
BXU06_RS04650	COG0154	amidase activity
BXU06_RS04665	COG0525	valine-tRNA ligase activity
BXU06_RS04685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BXU06_RS04690	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXU06_RS04695	COG1752	Esterase of the alpha-beta hydrolase superfamily
BXU06_RS04700	COG0765	amino acid transport
BXU06_RS04715	COG0513	Belongs to the DEAD box helicase family
BXU06_RS04720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BXU06_RS04740	COG3706	GGDEF domain
BXU06_RS04760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BXU06_RS04770	COG2095	MarC family integral membrane protein
BXU06_RS04790	COG0598	Magnesium transport protein CorA
BXU06_RS04800	COG0704	Plays a role in the regulation of phosphate uptake
BXU06_RS04805	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BXU06_RS04810	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BXU06_RS04815	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BXU06_RS04825	COG0328	RNA-DNA hybrid ribonuclease activity
BXU06_RS04830	COG2226	methyltransferase
BXU06_RS04835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXU06_RS04840	COG1388	LysM domain
BXU06_RS04840	COG0741	lytic transglycosylase activity
BXU06_RS04850	COG0546	phosphoglycolate phosphatase activity
BXU06_RS04855	COG0513	Belongs to the DEAD box helicase family
BXU06_RS04880	COG0542	response to heat
BXU06_RS04885	COG0840	transmembrane signaling receptor activity
BXU06_RS04905	COG2204	response regulator
BXU06_RS04915	COG1396	sequence-specific DNA binding
BXU06_RS04920	COG3135	benzoate transporter
BXU06_RS04925	COG0513	Belongs to the DEAD box helicase family
BXU06_RS04935	COG2084	Dehydrogenase
BXU06_RS04940	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BXU06_RS04950	COG1024	Enoyl-CoA hydratase
BXU06_RS04955	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BXU06_RS04955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU06_RS04965	COG0564	pseudouridine synthase activity
BXU06_RS04980	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BXU06_RS04985	COG1674	ftsk spoiiie
BXU06_RS05015	COG1136	(ABC) transporter
BXU06_RS05045	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BXU06_RS05060	COG0254	rRNA binding
BXU06_RS05080	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BXU06_RS05140	COG1136	(ABC) transporter
BXU06_RS05160	COG1129	ABC transporter
BXU06_RS05175	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU06_RS05185	COG0583	DNA-binding transcription factor activity
BXU06_RS05190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BXU06_RS05195	COG0066	3-isopropylmalate dehydratase activity
BXU06_RS05200	COG0473	3-isopropylmalate dehydrogenase activity
BXU06_RS05230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BXU06_RS05235	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BXU06_RS05250	COG3220	belongs to the UPF0276 family
BXU06_RS05270	COG1279	arginine transmembrane transporter activity
BXU06_RS05275	COG1666	GTP binding
BXU06_RS05290	COG0137	argininosuccinate synthase activity
BXU06_RS05295	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BXU06_RS05310	COG2823	Periplasmic or secreted lipoprotein
BXU06_RS05315	COG0488	(ABC) transporter
BXU06_RS05320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BXU06_RS05325	COG1765	OsmC-like protein
BXU06_RS05335	COG2824	Alkylphosphonate utilization operon protein PhnA
BXU06_RS05345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BXU06_RS05355	COG3012	SEC-C Motif Domain Protein
BXU06_RS05380	COG0028	Belongs to the TPP enzyme family
BXU06_RS05385	COG0440	acetolactate synthase activity
BXU06_RS05400	COG5433	transposase activity
BXU06_RS05410	COG3123	guanosine phosphorylase activity
BXU06_RS05415	COG1393	Belongs to the ArsC family
BXU06_RS05420	COG0318	PFAM AMP-dependent synthetase and ligase
BXU06_RS05425	COG0779	Required for maturation of 30S ribosomal subunits
BXU06_RS05430	COG2251	uridine kinase activity
BXU06_RS05430	COG0195	Participates in both transcription termination and antitermination
BXU06_RS05435	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BXU06_RS05440	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BXU06_RS05445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BXU06_RS05450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BXU06_RS05455	COG1185	polyribonucleotide nucleotidyltransferase activity
BXU06_RS05460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXU06_RS05475	COG1360	Flagellar Motor Protein
BXU06_RS05490	COG0174	glutamine synthetase
BXU06_RS05495	COG1396	sequence-specific DNA binding
BXU06_RS05495	COG1917	Cupin 2, conserved barrel domain protein
BXU06_RS05500	COG1309	transcriptional regulator
BXU06_RS05505	COG0859	PFAM glycosyl transferase family 9
BXU06_RS05525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BXU06_RS05530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BXU06_RS05535	COG0159	tryptophan synthase activity
BXU06_RS05540	COG0133	tryptophan synthase activity
BXU06_RS05545	COG0135	phosphoribosylanthranilate isomerase activity
BXU06_RS05550	COG0101	tRNA pseudouridine synthase activity
BXU06_RS05580	COG1607	acyl-coa hydrolase
BXU06_RS05585	COG0697	spore germination
BXU06_RS05590	COG0659	secondary active sulfate transmembrane transporter activity
BXU06_RS05605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BXU06_RS05610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_RS05615	COG1116	anion transmembrane transporter activity
BXU06_RS05620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BXU06_RS05630	COG0243	molybdopterin cofactor binding
BXU06_RS05650	COG1024	Enoyl-CoA hydratase
BXU06_RS05655	COG0596	Alpha beta hydrolase
BXU06_RS05660	COG1472	Belongs to the glycosyl hydrolase 3 family
BXU06_RS05665	COG0494	nUDIX hydrolase
BXU06_RS05670	COG2900	Belongs to the SlyX family
BXU06_RS05680	COG0840	transmembrane signaling receptor activity
BXU06_RS05700	COG3039	Transposase
BXU06_RS05710	COG0330	HflC and HflK could
BXU06_RS05715	COG0840	transmembrane signaling receptor activity
BXU06_RS05730	COG0778	Nitroreductase
BXU06_RS05755	COG3311	Transcriptional regulator
BXU06_RS05790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BXU06_RS05800	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BXU06_RS05825	COG0300	oxidoreductase activity
BXU06_RS05830	COG0861	Integral membrane protein TerC family
BXU06_RS05840	COG2003	Belongs to the UPF0758 family
BXU06_RS05845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BXU06_RS05855	COG2096	Adenosyltransferase
BXU06_RS05865	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BXU06_RS05870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BXU06_RS05895	COG2832	Protein of unknown function (DUF454)
BXU06_RS05900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BXU06_RS05915	COG0494	nUDIX hydrolase
BXU06_RS05930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_RS05960	COG2902	Dehydrogenase
BXU06_RS05970	COG5433	transposase activity
BXU06_RS05975	COG0583	DNA-binding transcription factor activity
BXU06_RS05985	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BXU06_RS05995	COG3093	addiction module antidote protein HigA
BXU06_RS06000	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BXU06_RS06005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXU06_RS06010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BXU06_RS06020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXU06_RS06030	COG0420	3'-5' exonuclease activity
BXU06_RS06035	COG0419	ATPase involved in DNA repair
BXU06_RS06055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BXU06_RS06060	COG0280	phosphate acetyltransferase
BXU06_RS06060	COG0857	belongs to the CobB CobQ family
BXU06_RS06070	COG2733	membrane
BXU06_RS06080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BXU06_RS06090	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXU06_RS06095	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXU06_RS06100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BXU06_RS06105	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXU06_RS06125	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BXU06_RS06135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BXU06_RS06140	COG0233	cytoplasmic translational termination
BXU06_RS06145	COG0528	UMP kinase activity
BXU06_RS06150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BXU06_RS06155	COG0052	Belongs to the universal ribosomal protein uS2 family
BXU06_RS06175	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BXU06_RS06180	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BXU06_RS06190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_RS06200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BXU06_RS06215	COG3162	membrane
BXU06_RS06220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXU06_RS06225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXU06_RS06265	COG3039	Transposase
BXU06_RS06275	COG0700	Nucleoside recognition
BXU06_RS06280	COG0840	transmembrane signaling receptor activity
BXU06_RS06290	COG0675	Transposase, IS605 OrfB family
BXU06_RS06310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BXU06_RS06320	COG0406	alpha-ribazole phosphatase activity
BXU06_RS06325	COG2944	sequence-specific DNA binding
BXU06_RS06340	COG5433	transposase activity
BXU06_RS06355	COG3275	phosphorelay sensor kinase activity
BXU06_RS06370	COG0756	dUTP diphosphatase activity
BXU06_RS06375	COG5433	transposase activity
BXU06_RS06380	COG3622	Belongs to the hyi family
BXU06_RS06400	COG3622	Belongs to the hyi family
BXU06_RS06405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU06_RS06410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU06_RS06420	COG2350	Protein conserved in bacteria
BXU06_RS06425	COG2917	probably involved in intracellular septation
BXU06_RS06430	COG1643	Atp-dependent helicase
BXU06_RS06450	COG1763	Mo-molybdopterin cofactor biosynthetic process
BXU06_RS06460	COG0735	belongs to the Fur family
BXU06_RS06465	COG0523	cobalamin synthesis protein
BXU06_RS06470	COG1121	(ABC) transporter
BXU06_RS06490	COG0251	oxidation-reduction process
BXU06_RS06525	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BXU06_RS06550	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BXU06_RS06555	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BXU06_RS06595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_RS06600	COG1846	Transcriptional regulator
BXU06_RS06605	COG0386	Belongs to the glutathione peroxidase family
BXU06_RS06615	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BXU06_RS06625	COG0840	transmembrane signaling receptor activity
BXU06_RS06635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BXU06_RS06665	COG0038	chloride channel
BXU06_RS06675	COG4206	TonB-dependent receptor
BXU06_RS06685	COG3022	response to hydroperoxide
BXU06_RS06690	COG0628	permease
BXU06_RS06695	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BXU06_RS06700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BXU06_RS06710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXU06_RS06710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BXU06_RS06750	COG0793	Belongs to the peptidase S41A family
BXU06_RS06755	COG4942	peptidase
BXU06_RS06765	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BXU06_RS06780	COG2814	Major facilitator Superfamily
BXU06_RS06785	COG0629	single-stranded DNA binding
BXU06_RS06790	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BXU06_RS06800	COG3128	pkhd-type hydroxylase
BXU06_RS06805	COG4774	siderophore transport
BXU06_RS06810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BXU06_RS06880	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BXU06_RS06895	COG2081	HI0933 family
BXU06_RS06900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXU06_RS06905	COG0024	Methionine aminopeptidase
BXU06_RS06920	COG3411	Ferredoxin
BXU06_RS06930	COG1420	regulation of RNA biosynthetic process
BXU06_RS06945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BXU06_RS06950	COG2137	regulation of response to DNA damage stimulus
BXU06_RS06955	COG0840	transmembrane signaling receptor activity
BXU06_RS06970	COG0840	transmembrane signaling receptor activity
BXU06_RS06980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BXU06_RS06990	COG0129	dihydroxy-acid dehydratase activity
BXU06_RS07000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BXU06_RS07005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BXU06_RS07015	COG2951	lytic endotransglycosylase activity
BXU06_RS07025	COG0675	Transposase, IS605 OrfB family
BXU06_RS07030	COG0556	nucleotide-excision repair
BXU06_RS07040	COG0556	nucleotide-excision repair
BXU06_RS07055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BXU06_RS07060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXU06_RS07065	COG0443	Heat shock 70 kDa protein
BXU06_RS07080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BXU06_RS07110	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_RS07115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BXU06_RS07120	COG0321	lipoyl(octanoyl) transferase activity
BXU06_RS07125	COG2921	Belongs to the UPF0250 family
BXU06_RS07130	COG1686	Belongs to the peptidase S11 family
BXU06_RS07160	COG4628	conserved protein (DUF2132)
BXU06_RS07170	COG3039	Transposase
BXU06_RS07190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BXU06_RS07200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BXU06_RS07210	COG0482	sulfurtransferase activity
BXU06_RS07250	COG1196	nuclear chromosome segregation
BXU06_RS07275	COG0488	(ABC) transporter
BXU06_RS07280	COG3706	GGDEF domain
BXU06_RS07285	COG0492	ferredoxin-NADP+ reductase activity
BXU06_RS07295	COG4191	Histidine kinase
BXU06_RS07310	COG1518	maintenance of DNA repeat elements
BXU06_RS07315	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BXU06_RS07335	COG1337	RAMP superfamily
BXU06_RS07365	COG0564	pseudouridine synthase activity
BXU06_RS07370	COG0259	pyridoxamine-phosphate oxidase activity
BXU06_RS07380	COG1136	(ABC) transporter
BXU06_RS07385	COG1511	domain protein
BXU06_RS07385	COG3264	Mechanosensitive ion channel
BXU06_RS07400	COG3568	Endonuclease Exonuclease Phosphatase
BXU06_RS07415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXU06_RS07420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXU06_RS07420	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BXU06_RS07425	COG1217	gtp-binding protein TYPA
BXU06_RS07430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXU06_RS07435	COG0402	S-adenosylhomocysteine deaminase activity
BXU06_RS07440	COG3842	ATPase activity
BXU06_RS07450	COG1176	ABC-type spermidine putrescine transport system, permease component I
BXU06_RS07455	COG1177	transmembrane transport
BXU06_RS07480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BXU06_RS07490	COG1960	acyl-CoA dehydrogenase activity
BXU06_RS07500	COG4172	Belongs to the ABC transporter superfamily
BXU06_RS07505	COG0791	NLP P60 protein
BXU06_RS07510	COG0488	(ABC) transporter
BXU06_RS07525	COG0285	dihydrofolate synthase activity
BXU06_RS07550	COG0675	Transposase, IS605 OrfB family
BXU06_RS07555	COG0678	peroxiredoxin activity
BXU06_RS07555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BXU06_RS07560	COG0741	lytic transglycosylase activity
BXU06_RS07560	COG0739	heme binding
BXU06_RS07560	COG1196	nuclear chromosome segregation
BXU06_RS07565	COG0702	epimerase
BXU06_RS07570	COG0617	tRNA 3'-terminal CCA addition
BXU06_RS07580	COG2258	MOSC domain
BXU06_RS07585	COG1607	acyl-coa hydrolase
BXU06_RS07595	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXU06_RS07595	COG1024	Enoyl-CoA hydratase
BXU06_RS07600	COG0183	Belongs to the thiolase family
BXU06_RS07605	COG0675	Transposase, IS605 OrfB family
BXU06_RS07620	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BXU06_RS07620	COG0506	proline dehydrogenase activity
BXU06_RS07620	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BXU06_RS07635	COG0287	Prephenate dehydrogenase
BXU06_RS07645	COG0494	nUDIX hydrolase
BXU06_RS07660	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BXU06_RS07670	COG0842	Transport permease protein
BXU06_RS07675	COG0842	Transport permease protein
BXU06_RS07675	COG1129	ABC transporter
BXU06_RS07680	COG2010	Cytochrome c
BXU06_RS07685	COG1131	(ABC) transporter
BXU06_RS07690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXU06_RS07705	COG5433	transposase activity
BXU06_RS07710	COG4206	TonB-dependent receptor
BXU06_RS07715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXU06_RS07720	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BXU06_RS07730	COG1797	cobyrinic acid a,c-diamide synthase activity
BXU06_RS07745	COG1937	Protein conserved in bacteria
BXU06_RS07755	COG2217	Heavy metal translocating P-type atpase
BXU06_RS07775	COG4239	(ABC) transporter, permease
BXU06_RS07785	COG4174	ABC transporter (Permease)
BXU06_RS07790	COG4166	transmembrane transport
BXU06_RS07800	COG1722	exodeoxyribonuclease VII activity
BXU06_RS07805	COG0142	geranyltranstransferase activity
BXU06_RS07810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BXU06_RS07815	COG3174	membrane
BXU06_RS07835	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BXU06_RS07840	COG0534	Mate efflux family protein
BXU06_RS07865	COG0675	Transposase, IS605 OrfB family
BXU06_RS07880	COG1199	ATP-dependent helicase activity
BXU06_RS07890	COG0675	Transposase, IS605 OrfB family
BXU06_RS07900	COG0675	Transposase, IS605 OrfB family
BXU06_RS07945	COG1469	GTP cyclohydrolase I activity
BXU06_RS07960	COG0675	Transposase, IS605 OrfB family
BXU06_RS07980	COG0501	Belongs to the peptidase M48B family
BXU06_RS07995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BXU06_RS08025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_RS08030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_RS08035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BXU06_RS08055	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BXU06_RS08065	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BXU06_RS08075	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BXU06_RS08100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BXU06_RS08110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BXU06_RS08115	COG0795	lipopolysaccharide-transporting ATPase activity
BXU06_RS08125	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BXU06_RS08150	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_RS08155	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BXU06_RS08160	COG1562	ergosterol biosynthetic process
BXU06_RS08190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BXU06_RS08195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXU06_RS08195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXU06_RS08225	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BXU06_RS08230	COG0751	glycine-tRNA ligase activity
BXU06_RS08240	COG0752	glycyl-tRNA synthetase alpha subunit
BXU06_RS08250	COG0436	Aminotransferase
BXU06_RS08285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BXU06_RS08285	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BXU06_RS08295	COG0675	Transposase, IS605 OrfB family
BXU06_RS08300	COG1492	cobalamin metabolic process
BXU06_RS08315	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BXU06_RS08320	COG1595	DNA-templated transcription, initiation
BXU06_RS08335	COG0791	NLP P60 protein
BXU06_RS08345	COG0745	RESPONSE REGULATOR receiver
BXU06_RS08350	COG2205	protein histidine kinase activity
BXU06_RS08355	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BXU06_RS08360	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BXU06_RS08365	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BXU06_RS08375	COG3300	MHYT domain
BXU06_RS08375	COG5001	Diguanylate cyclase
BXU06_RS08380	COG0675	Transposase, IS605 OrfB family
BXU06_RS08385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BXU06_RS08415	COG0175	sulfate reduction
BXU06_RS08420	COG2895	sulfate adenylyltransferase (ATP) activity
BXU06_RS08430	COG0309	Hydrogenase expression formation protein (HypE)
BXU06_RS08445	COG2827	Endonuclease containing a URI domain
BXU06_RS08465	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BXU06_RS08470	COG1773	rubredoxin
BXU06_RS08535	COG0322	excinuclease ABC activity
BXU06_RS08540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BXU06_RS08580	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BXU06_RS08585	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BXU06_RS08590	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BXU06_RS08595	COG1428	Deoxynucleoside kinase
BXU06_RS08605	COG0617	tRNA 3'-terminal CCA addition
BXU06_RS08615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BXU06_RS08640	COG0183	Belongs to the thiolase family
BXU06_RS08645	COG0840	transmembrane signaling receptor activity
BXU06_RS08655	COG0675	Transposase, IS605 OrfB family
BXU06_RS08660	COG0625	glutathione transferase activity
BXU06_RS08695	COG0730	response to heat
BXU06_RS08710	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BXU06_RS08715	COG3284	Transcriptional regulator
BXU06_RS08755	COG1881	PFAM PEBP family protein
BXU06_RS08780	COG0281	malic enzyme
BXU06_RS08780	COG0280	phosphate acetyltransferase
BXU06_RS08800	COG2226	methyltransferase
BXU06_RS08805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXU06_RS08805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXU06_RS08810	COG0489	protein tyrosine kinase activity
BXU06_RS08815	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BXU06_RS08875	COG1122	ATPase activity
BXU06_RS08880	COG0583	DNA-binding transcription factor activity
BXU06_RS08920	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BXU06_RS08930	COG0312	modulator of DNA gyrase
BXU06_RS08935	COG3028	Belongs to the UPF0307 family
BXU06_RS08940	COG0521	Mo-molybdopterin cofactor biosynthetic process
BXU06_RS08945	COG0429	hydrolase of the alpha beta-hydrolase fold
BXU06_RS08950	COG0134	indole-3-glycerol-phosphate synthase activity
BXU06_RS08960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BXU06_RS08975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BXU06_RS08980	COG3842	ATPase activity
BXU06_RS09010	COG0022	dehydrogenase e1 component
BXU06_RS09020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_RS09035	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BXU06_RS09040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BXU06_RS09060	COG2062	phosphohistidine phosphatase, SixA
BXU06_RS09065	COG1346	cytolysis
BXU06_RS09080	COG3161	chorismate lyase activity
BXU06_RS09085	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BXU06_RS09095	COG2816	NAD+ diphosphatase activity
BXU06_RS09105	COG0037	tRNA processing
BXU06_RS09110	COG0825	malonyl-CoA metabolic process
BXU06_RS09140	COG2195	Cleaves the N-terminal amino acid of tripeptides
BXU06_RS09145	COG5265	(ABC) transporter
BXU06_RS09150	COG2967	ApaG domain
BXU06_RS09155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BXU06_RS09185	COG3138	arginine N-succinyltransferase
BXU06_RS09225	COG1960	acyl-CoA dehydrogenase activity
BXU06_RS09230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BXU06_RS09235	COG1024	Enoyl-CoA hydratase
BXU06_RS09255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXU06_RS09260	COG0675	Transposase, IS605 OrfB family
BXU06_RS09265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_RS09270	COG0348	domain, Protein
BXU06_RS09275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BXU06_RS09280	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BXU06_RS09285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BXU06_RS09300	COG2188	Transcriptional regulator
BXU06_RS09305	COG1840	ABC-type Fe3 transport system, periplasmic component
BXU06_RS09315	COG3842	ATPase activity
BXU06_RS09335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU06_RS09340	COG0840	transmembrane signaling receptor activity
BXU06_RS09355	COG0717	Belongs to the dCTP deaminase family
BXU06_RS09395	COG0840	transmembrane signaling receptor activity
BXU06_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_RS09410	COG3237	CsbD-like
BXU06_RS09425	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BXU06_RS09465	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BXU06_RS09480	COG3829	transcription factor binding
BXU06_RS09495	COG1335	isochorismatase
BXU06_RS09500	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BXU06_RS09505	COG1561	YicC-like family, N-terminal region
BXU06_RS09520	COG4181	ATPase activity
BXU06_RS09525	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BXU06_RS09540	COG0557	exoribonuclease II activity
BXU06_RS09545	COG0753	catalase activity
BXU06_RS09570	COG4774	siderophore transport
BXU06_RS09575	COG3128	pkhd-type hydroxylase
BXU06_RS09580	COG5433	transposase activity
BXU06_RS09610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXU06_RS09620	COG5002	protein histidine kinase activity
BXU06_RS09620	COG2198	Histidine kinase
BXU06_RS09620	COG0784	Response regulator, receiver
BXU06_RS09625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BXU06_RS09635	COG0215	cysteine-tRNA ligase activity
BXU06_RS09660	COG1706	bacterial-type flagellum-dependent cell motility
BXU06_RS09665	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BXU06_RS09675	COG4787	bacterial-type flagellum-dependent cell motility
BXU06_RS09690	COG1558	bacterial-type flagellum-dependent cell motility
BXU06_RS09695	COG1815	bacterial-type flagellum-dependent cell motility
BXU06_RS09705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BXU06_RS09715	COG0730	response to heat
BXU06_RS09760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BXU06_RS09815	COG2257	FlhB HrpN YscU SpaS Family
BXU06_RS09820	COG2084	Dehydrogenase
BXU06_RS09840	COG0675	Transposase, IS605 OrfB family
BXU06_RS09845	COG2239	Acts as a magnesium transporter
BXU06_RS09850	COG2890	protein-(glutamine-N5) methyltransferase activity
BXU06_RS09855	COG2252	PERMEase
BXU06_RS09860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BXU06_RS09870	COG0583	DNA-binding transcription factor activity
BXU06_RS09875	COG0840	transmembrane signaling receptor activity
BXU06_RS09895	COG0840	transmembrane signaling receptor activity
BXU06_RS09900	COG0242	peptide deformylase activity
BXU06_RS09920	COG1573	uracil-dna glycosylase
BXU06_RS09940	COG1570	exodeoxyribonuclease VII activity
BXU06_RS09945	COG0811	peptide transport
BXU06_RS09950	COG0848	biopolymer transport protein
BXU06_RS09955	COG1663	tetraacyldisaccharide 4'-kinase activity
BXU06_RS09960	COG2835	tetraacyldisaccharide 4'-kinase activity
BXU06_RS09965	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BXU06_RS09970	COG0563	adenylate kinase activity
BXU06_RS09975	COG0205	6-phosphofructokinase activity
BXU06_RS09990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BXU06_RS09995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BXU06_RS10025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BXU06_RS10030	COG0123	including yeast histone deacetylase and acetoin utilization protein
BXU06_RS10035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BXU06_RS10040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXU06_RS10050	COG2201	protein-glutamate methylesterase activity
BXU06_RS10060	COG1677	Flagellar hook-basal body complex protein FliE
BXU06_RS10080	COG1157	protein secretion by the type III secretion system
BXU06_RS10105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BXU06_RS10120	COG1987	bacterial-type flagellum assembly
BXU06_RS10130	COG0217	transcriptional regulatory protein
BXU06_RS10135	COG0006	proline dipeptidase activity
BXU06_RS10140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXU06_RS10145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXU06_RS10165	COG2801	Transposase and inactivated derivatives
BXU06_RS10180	COG0484	heat shock protein binding
BXU06_RS10185	COG0443	Heat shock 70 kDa protein
BXU06_RS10190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BXU06_RS10200	COG3706	GGDEF domain
BXU06_RS10215	COG0826	peptidase U32
BXU06_RS10225	COG0004	ammonium transporteR
BXU06_RS10250	COG0348	domain, Protein
BXU06_RS10270	COG3278	Belongs to the heme-copper respiratory oxidase family
BXU06_RS10280	COG0308	aminopeptidase N
BXU06_RS10285	COG0477	Major facilitator Superfamily
BXU06_RS10315	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BXU06_RS10320	COG2864	formate dehydrogenase
BXU06_RS10325	COG0437	4 iron, 4 sulfur cluster binding
BXU06_RS10330	COG0243	molybdopterin cofactor binding
BXU06_RS10330	COG3383	formate dehydrogenase (NAD+) activity
BXU06_RS10340	COG0788	formyltetrahydrofolate deformylase activity
BXU06_RS10345	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BXU06_RS10375	COG1530	ribonuclease E activity
BXU06_RS10395	COG0616	signal peptide processing
BXU06_RS10395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BXU06_RS10405	COG2308	Evidence 4 Homologs of previously reported genes of
BXU06_RS10425	COG0167	dihydroorotate dehydrogenase activity
BXU06_RS10430	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BXU06_RS10435	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BXU06_RS10445	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXU06_RS10450	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BXU06_RS10455	COG0495	leucyl-tRNA aminoacylation
BXU06_RS10465	COG1466	dna polymerase III delta subunit
BXU06_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_RS10475	COG0488	(ABC) transporter
BXU06_RS10480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXU06_RS10485	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BXU06_RS10495	COG2850	peptidyl-arginine hydroxylation
BXU06_RS10510	COG0183	Belongs to the thiolase family
BXU06_RS10515	COG3243	poly(R)-hydroxyalkanoic acid synthase
BXU06_RS10520	COG0679	Auxin Efflux Carrier
BXU06_RS10530	COG4191	Histidine kinase
BXU06_RS10535	COG2204	response regulator
BXU06_RS10545	COG5001	Diguanylate cyclase
BXU06_RS10545	COG3300	MHYT domain
BXU06_RS10550	COG1970	mechanosensitive ion channel activity
BXU06_RS10565	COG1376	ErfK ybiS ycfS ynhG family protein
BXU06_RS10575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BXU06_RS10585	COG0840	transmembrane signaling receptor activity
BXU06_RS10630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BXU06_RS10640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BXU06_RS10650	COG0802	atpase or kinase
BXU06_RS10655	COG0860	N-Acetylmuramoyl-L-alanine amidase
BXU06_RS10665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BXU06_RS10670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BXU06_RS10680	COG0084	hydrolase, TatD family'
BXU06_RS10690	COG0268	Binds directly to 16S ribosomal RNA
BXU06_RS10725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BXU06_RS10740	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BXU06_RS10745	COG0583	DNA-binding transcription factor activity
BXU06_RS10750	COG3045	CreA protein
BXU06_RS10765	COG2132	Multicopper oxidase
BXU06_RS10775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXU06_RS10810	COG0642	Histidine kinase
BXU06_RS10815	COG0840	transmembrane signaling receptor activity
BXU06_RS10825	COG0675	Transposase, IS605 OrfB family
BXU06_RS10845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXU06_RS10850	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BXU06_RS10860	COG0284	orotidine-5'-phosphate decarboxylase activity
BXU06_RS10885	COG2119	membrane
BXU06_RS10895	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BXU06_RS10900	COG0504	CTP synthase activity
BXU06_RS10905	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BXU06_RS10910	COG0148	phosphopyruvate hydratase activity
BXU06_RS10915	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BXU06_RS10925	COG2914	Belongs to the UPF0125 (RnfH) family
BXU06_RS10930	COG2867	negative regulation of translational initiation
BXU06_RS10935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BXU06_RS10945	COG1301	dicarboxylic acid transport
BXU06_RS10955	COG0583	DNA-binding transcription factor activity
BXU06_RS10960	COG0776	regulation of translation
BXU06_RS10970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BXU06_RS10980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BXU06_RS10985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BXU06_RS10990	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BXU06_RS10995	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BXU06_RS11000	COG0196	riboflavin kinase activity
BXU06_RS11015	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BXU06_RS11020	COG0175	sulfate reduction
BXU06_RS11025	COG0583	DNA-binding transcription factor activity
BXU06_RS11035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BXU06_RS11035	COG1648	precorrin-2 dehydrogenase activity
BXU06_RS11040	COG2010	Cytochrome c
BXU06_RS11050	COG1845	cytochrome c oxidase, subunit III
BXU06_RS11080	COG4654	Cytochrome c, class I
BXU06_RS11085	COG2010	Cytochrome c
BXU06_RS11095	COG1522	sequence-specific DNA binding
BXU06_RS11110	COG0535	radical SAM domain protein
BXU06_RS11145	COG0318	PFAM AMP-dependent synthetase and ligase
BXU06_RS11155	COG1187	pseudouridine synthase activity
BXU06_RS11160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BXU06_RS11170	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BXU06_RS11185	COG0850	regulation of cytokinetic process
BXU06_RS11190	COG2894	cell division
BXU06_RS11195	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BXU06_RS11200	COG0583	DNA-binding transcription factor activity
BXU06_RS11210	COG0675	Transposase, IS605 OrfB family
BXU06_RS11230	COG0459	protein refolding
BXU06_RS11235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BXU06_RS11240	COG0723	plastoquinol--plastocyanin reductase activity
BXU06_RS11245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BXU06_RS11250	COG2857	Cytochrome c1
BXU06_RS11255	COG0625	glutathione transferase activity
BXU06_RS11260	COG2969	positive regulation of protein catabolic process
BXU06_RS11265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXU06_RS11280	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BXU06_RS11285	COG1534	Rna-binding protein
BXU06_RS11315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU06_RS11330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BXU06_RS11345	COG0675	Transposase, IS605 OrfB family
BXU06_RS11360	COG1960	acyl-CoA dehydrogenase activity
BXU06_RS11375	COG2030	dehydratase
BXU06_RS11390	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BXU06_RS11395	COG0583	DNA-binding transcription factor activity
BXU06_RS11410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BXU06_RS11415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BXU06_RS11420	COG2833	Protein of unknown function (DUF455)
BXU06_RS11430	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BXU06_RS11435	COG1032	radical SAM domain protein
BXU06_RS11465	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BXU06_RS11470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BXU06_RS11490	COG1309	transcriptional regulator
BXU06_RS11510	COG2193	ferroxidase activity
BXU06_RS11520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXU06_RS11525	COG1309	transcriptional regulator
BXU06_RS11530	COG1902	pentaerythritol trinitrate reductase activity
BXU06_RS11550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BXU06_RS11550	COG2755	lipolytic protein G-D-S-L family
BXU06_RS11560	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_RS11575	COG0037	tRNA processing
BXU06_RS11580	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BXU06_RS11585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BXU06_RS11605	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_RS11610	COG2070	2-Nitropropane dioxygenase
BXU06_RS11625	COG0840	transmembrane signaling receptor activity
BXU06_RS11640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BXU06_RS11645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BXU06_RS11665	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BXU06_RS11675	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BXU06_RS11680	COG0252	asparaginase activity
BXU06_RS11690	COG0730	response to heat
BXU06_RS11735	COG2977	Belongs to the P-Pant transferase superfamily
BXU06_RS11740	COG1021	2,3-dihydroxybenzoate-AMP ligase
BXU06_RS11770	COG1132	(ABC) transporter
BXU06_RS11775	COG4771	TonB-dependent receptor
BXU06_RS11790	COG4771	TonB-dependent receptor
BXU06_RS11800	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BXU06_RS11810	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BXU06_RS11830	COG0123	including yeast histone deacetylase and acetoin utilization protein
BXU06_RS11835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BXU06_RS11845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BXU06_RS11850	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BXU06_RS11855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BXU06_RS11860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXU06_RS11860	COG1042	CoA-binding domain protein
BXU06_RS11860	COG0045	succinate-CoA ligase (ADP-forming) activity
BXU06_RS11865	COG0228	four-way junction DNA binding
BXU06_RS11870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BXU06_RS11875	COG0336	Belongs to the RNA methyltransferase TrmD family
BXU06_RS11880	COG0335	large ribosomal subunit rRNA binding
BXU06_RS11890	COG0542	response to heat
BXU06_RS11895	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BXU06_RS11905	COG1278	Cold shock
BXU06_RS11910	COG1278	Cold shock
BXU06_RS11925	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BXU06_RS11930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BXU06_RS11965	COG1959	2 iron, 2 sulfur cluster binding
BXU06_RS11970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BXU06_RS11970	COG1017	nitric oxide dioxygenase activity
BXU06_RS11985	COG0004	ammonium transporteR
BXU06_RS12000	COG0277	FAD linked oxidase domain protein
BXU06_RS12010	COG0415	Belongs to the DNA photolyase family
BXU06_RS12015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BXU06_RS12030	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BXU06_RS12045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXU06_RS12050	COG0438	transferase activity, transferring glycosyl groups
BXU06_RS12075	COG0367	asparagine synthase
BXU06_RS12100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BXU06_RS12130	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BXU06_RS12135	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BXU06_RS12140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BXU06_RS12150	COG1560	Kdo2-lipid A biosynthetic process
BXU06_RS12160	COG1007	ATP synthesis coupled electron transport
BXU06_RS12175	COG0713	ATP synthesis coupled electron transport
BXU06_RS12185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXU06_RS12190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BXU06_RS12195	COG1034	ATP synthesis coupled electron transport
BXU06_RS12200	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BXU06_RS12210	COG0649	NAD binding
BXU06_RS12215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXU06_RS12220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXU06_RS12225	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXU06_RS12235	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BXU06_RS12240	COG0149	triose-phosphate isomerase activity
BXU06_RS12250	COG0573	inorganic phosphate transmembrane transporter activity
BXU06_RS12255	COG0581	inorganic phosphate transmembrane transporter activity
BXU06_RS12260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BXU06_RS12265	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BXU06_RS12270	COG1196	nuclear chromosome segregation
BXU06_RS12285	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BXU06_RS12295	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BXU06_RS12300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BXU06_RS12310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BXU06_RS12315	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BXU06_RS12320	COG0193	aminoacyl-tRNA hydrolase activity
BXU06_RS12325	COG0012	GTP binding
BXU06_RS12340	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BXU06_RS12360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BXU06_RS12400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BXU06_RS12410	COG2226	methyltransferase
BXU06_RS12420	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BXU06_RS12425	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BXU06_RS12430	COG0511	ligase activity, forming carbon-carbon bonds
BXU06_RS12435	COG0439	Biotin carboxylase
BXU06_RS12440	COG2264	protein methyltransferase activity
BXU06_RS12450	COG0473	3-isopropylmalate dehydrogenase activity
BXU06_RS12455	COG0438	transferase activity, transferring glycosyl groups
BXU06_RS12515	COG1104	cysteine desulfurase activity
BXU06_RS12520	COG0822	iron-sulfur transferase activity
BXU06_RS12530	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BXU06_RS12535	COG0443	Heat shock 70 kDa protein
BXU06_RS12545	COG2975	iron-sulfur cluster assembly
BXU06_RS12550	COG3550	peptidyl-serine autophosphorylation
BXU06_RS12565	COG1620	l-lactate permease
BXU06_RS12575	COG1139	Iron-sulfur cluster binding protein
BXU06_RS12585	COG0247	lactate metabolic process
BXU06_RS12590	COG2186	Transcriptional regulator
BXU06_RS12595	COG3135	benzoate transporter
BXU06_RS12600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_RS12605	COG0606	chelatase, subunit chli
BXU06_RS12620	COG0004	ammonium transporteR
BXU06_RS12630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BXU06_RS12635	COG0586	Pfam SNARE associated Golgi protein
BXU06_RS12645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BXU06_RS12650	COG0501	Belongs to the peptidase M48B family
BXU06_RS12660	COG2194	sulfuric ester hydrolase activity
BXU06_RS12665	COG0675	Transposase, IS605 OrfB family
BXU06_RS12675	COG3327	negative regulation of DNA-templated transcription, initiation
BXU06_RS12710	COG3077	Addiction module antitoxin, RelB DinJ family
BXU06_RS12715	COG3041	Addiction module toxin RelE StbE family
BXU06_RS12725	COG1739	Uncharacterized protein family UPF0029
BXU06_RS12735	COG4266	Belongs to the allantoicase family
BXU06_RS12745	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BXU06_RS12755	COG2351	hydroxyisourate hydrolase activity
BXU06_RS12805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BXU06_RS12810	COG2249	NAD(P)H dehydrogenase (quinone) activity
BXU06_RS12825	COG5433	transposase activity
BXU06_RS12830	COG1132	(ABC) transporter
BXU06_RS12840	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BXU06_RS12845	COG0741	lytic transglycosylase activity
BXU06_RS12855	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BXU06_RS12860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BXU06_RS12865	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BXU06_RS12875	COG3842	ATPase activity
BXU06_RS12885	COG1177	transmembrane transport
BXU06_RS12905	COG1295	ribonuclease BN
BXU06_RS12965	COG0426	domain, Protein
BXU06_RS12970	COG0633	Ferredoxin
BXU06_RS12990	COG0840	transmembrane signaling receptor activity
BXU06_RS13005	COG4251	negative regulation of phosphorylation
BXU06_RS13010	COG2205	protein histidine kinase activity
BXU06_RS13015	COG0784	Response regulator, receiver
BXU06_RS13040	COG0604	alcohol dehydrogenase
BXU06_RS13070	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BXU06_RS13090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BXU06_RS13125	COG0716	FMN binding
BXU06_RS13155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BXU06_RS13195	COG0003	Pfam Anion-transporting ATPase
BXU06_RS13225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXU06_RS13230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXU06_RS13240	COG0140	phosphoribosyl-ATP diphosphatase activity
BXU06_RS13245	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BXU06_RS13250	COG0107	imidazoleglycerol-phosphate synthase activity
BXU06_RS13255	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BXU06_RS13260	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BXU06_RS13265	COG0131	Imidazoleglycerol-phosphate dehydratase
BXU06_RS13270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BXU06_RS13290	COG0438	transferase activity, transferring glycosyl groups
BXU06_RS13295	COG0859	PFAM glycosyl transferase family 9
BXU06_RS13300	COG0726	polysaccharide deacetylase
BXU06_RS13305	COG0438	transferase activity, transferring glycosyl groups
BXU06_RS13310	COG1132	(ABC) transporter
BXU06_RS13315	COG0697	spore germination
BXU06_RS13370	COG0823	Involved in the tonB-independent uptake of proteins
BXU06_RS13425	COG0165	Argininosuccinate lyase
BXU06_RS13445	COG0418	dihydroorotase activity
BXU06_RS13475	COG1760	l-serine dehydratase
BXU06_RS13490	COG3245	cytochrome
BXU06_RS13500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BXU06_RS13505	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BXU06_RS13515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BXU06_RS13525	COG3845	ABC transporter
BXU06_RS13535	COG1079	Belongs to the binding-protein-dependent transport system permease family
BXU06_RS13540	COG0402	S-adenosylhomocysteine deaminase activity
BXU06_RS13560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_RS13565	COG1116	anion transmembrane transporter activity
BXU06_RS13580	COG0477	Major facilitator Superfamily
BXU06_RS13585	COG0583	DNA-binding transcription factor activity
BXU06_RS13595	COG0408	coproporphyrinogen oxidase activity
BXU06_RS13615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BXU06_RS13625	COG0840	transmembrane signaling receptor activity
BXU06_RS13630	COG0589	response to stress
BXU06_RS13635	COG1187	pseudouridine synthase activity
BXU06_RS13640	COG0840	transmembrane signaling receptor activity
BXU06_RS13655	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BXU06_RS13660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXU06_RS13665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXU06_RS13675	COG0189	ligase activity
BXU06_RS13705	COG1505	serine-type exopeptidase activity
BXU06_RS13710	COG1929	Belongs to the glycerate kinase type-1 family
BXU06_RS13725	COG1126	abc transporter atp-binding protein
BXU06_RS13730	COG0765	amino acid transport
BXU06_RS13735	COG0765	amino acid transport
BXU06_RS13740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXU06_RS13760	COG2205	protein histidine kinase activity
BXU06_RS13760	COG3292	Two component regulator propeller
BXU06_RS13760	COG0745	RESPONSE REGULATOR receiver
BXU06_RS13765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BXU06_RS13770	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BXU06_RS13775	COG0708	Exodeoxyribonuclease III
BXU06_RS13780	COG0840	transmembrane signaling receptor activity
BXU06_RS13785	COG0424	maF-like protein
BXU06_RS13800	COG1451	nucleotide metabolic process
BXU06_RS13820	COG1858	cytochrome C peroxidase
BXU06_RS13835	COG3300	MHYT domain
BXU06_RS13835	COG5001	Diguanylate cyclase
BXU06_RS13840	COG0772	Belongs to the SEDS family
BXU06_RS13845	COG0768	penicillin binding
BXU06_RS13855	COG1792	Involved in formation and maintenance of cell shape
BXU06_RS13860	COG1077	Cell shape determining protein MreB Mrl
BXU06_RS13865	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BXU06_RS13870	COG0154	amidase activity
BXU06_RS13875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BXU06_RS13895	COG0840	transmembrane signaling receptor activity
BXU06_RS13900	COG2040	homocysteine
BXU06_RS13905	COG2001	Belongs to the MraZ family
BXU06_RS13910	COG0275	rRNA processing
BXU06_RS13915	COG3116	cell division
BXU06_RS13925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BXU06_RS13930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BXU06_RS13935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXU06_RS13940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BXU06_RS13945	COG0772	Belongs to the SEDS family
BXU06_RS13950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BXU06_RS13955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXU06_RS13960	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXU06_RS13965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BXU06_RS13980	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BXU06_RS13985	COG0315	cyclic pyranopterin monophosphate synthase activity
BXU06_RS13995	COG3039	Transposase
BXU06_RS14085	COG1902	pentaerythritol trinitrate reductase activity
BXU06_RS14085	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXU06_RS14090	COG2197	response regulator
BXU06_RS14095	COG0675	Transposase, IS605 OrfB family
BXU06_RS14100	COG2198	Histidine kinase
BXU06_RS14100	COG2205	protein histidine kinase activity
BXU06_RS14100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXU06_RS14100	COG0784	Response regulator, receiver
BXU06_RS14110	COG0069	glutamate synthase activity
BXU06_RS14110	COG0070	glutamate synthase
BXU06_RS14110	COG0067	glutamate synthase
BXU06_RS14115	COG0493	'glutamate synthase
BXU06_RS14120	COG0523	cobalamin synthesis protein
BXU06_RS14125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BXU06_RS14130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BXU06_RS14135	COG0210	DNA helicase
BXU06_RS14145	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BXU06_RS14150	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BXU06_RS14155	COG2771	luxR family
BXU06_RS14155	COG2200	EAL domain
BXU06_RS14175	COG4208	sulfate ABC transporter
BXU06_RS14180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BXU06_RS14200	COG0583	DNA-binding transcription factor activity
BXU06_RS14215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BXU06_RS14230	COG0675	Transposase, IS605 OrfB family
BXU06_RS14235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXU06_RS14240	COG1120	ATPase activity
BXU06_RS14245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXU06_RS14250	COG4558	Periplasmic binding protein
BXU06_RS14255	COG3720	iron ion transport
BXU06_RS14300	COG5433	transposase activity
BXU06_RS14305	COG2801	Transposase and inactivated derivatives
BXU06_RS14330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BXU06_RS14330	COG0189	ligase activity
BXU06_RS14335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BXU06_RS14335	COG0189	ligase activity
BXU06_RS14350	COG2201	protein-glutamate methylesterase activity
BXU06_RS14355	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BXU06_RS14365	COG0835	chemotaxis
BXU06_RS14375	COG0643	Histidine kinase
BXU06_RS14375	COG2198	Histidine kinase
BXU06_RS14395	COG0745	RESPONSE REGULATOR receiver
BXU06_RS14400	COG0642	Histidine kinase
BXU06_RS14405	COG0675	Transposase, IS605 OrfB family
BXU06_RS14425	COG0675	Transposase, IS605 OrfB family
BXU06_RS14430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BXU06_RS14435	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BXU06_RS14440	COG1280	lysine exporter protein (LysE YggA)
BXU06_RS14445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BXU06_RS14475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BXU06_RS14495	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BXU06_RS14500	COG0440	acetolactate synthase activity
BXU06_RS14505	COG0028	Belongs to the TPP enzyme family
BXU06_RS14530	COG1999	signal sequence binding
BXU06_RS14535	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BXU06_RS14540	COG0688	phosphatidylethanolamine metabolic process
BXU06_RS14545	COG1183	phosphatidylcholine synthase activity
BXU06_RS14550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_RS14560	COG0604	alcohol dehydrogenase
BXU06_RS14565	COG1309	transcriptional regulator
BXU06_RS14600	COG0138	bifunctional purine biosynthesis protein purh
BXU06_RS14640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BXU06_RS14645	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BXU06_RS14650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BXU06_RS14655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BXU06_RS14660	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BXU06_RS14665	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BXU06_RS14670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BXU06_RS14680	COG0356	it plays a direct role in the translocation of protons across the membrane
BXU06_RS14695	COG1192	Involved in chromosome partitioning
BXU06_RS14700	COG0357	Ribosomal RNA small subunit methyltransferase G
BXU06_RS14705	COG0445	tRNA wobble uridine modification
BXU06_RS14725	COG1294	oxidase, subunit
BXU06_RS14745	COG1720	tRNA m6t6A37 methyltransferase activity
BXU06_RS14755	COG2200	EAL domain
BXU06_RS14755	COG3287	FIST C domain
BXU06_RS14755	COG2199	diguanylate cyclase activity
BXU06_RS14760	COG2823	Periplasmic or secreted lipoprotein
BXU06_RS14765	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BXU06_RS14770	COG0792	nuclease activity
BXU06_RS14775	COG3107	peptidoglycan biosynthetic process
BXU06_RS14800	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BXU06_RS14810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BXU06_RS14845	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BXU06_RS14850	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BXU06_RS14875	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BXU06_RS14880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BXU06_RS14895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU06_RS14900	COG5001	Diguanylate cyclase
BXU06_RS14900	COG5002	protein histidine kinase activity
BXU06_RS14935	COG2197	response regulator
BXU06_RS14975	COG0826	peptidase U32
BXU06_RS14985	COG2814	Major facilitator Superfamily
BXU06_RS15030	COG0789	Transcriptional regulator
BXU06_RS15035	COG1132	(ABC) transporter
BXU06_RS15065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BXU06_RS15065	COG2199	diguanylate cyclase activity
BXU06_RS15080	COG1965	Belongs to the frataxin family
BXU06_RS15085	COG1238	metal cluster binding
BXU06_RS15090	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BXU06_RS15095	COG1126	abc transporter atp-binding protein
BXU06_RS15100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXU06_RS15120	COG0824	Thioesterase
BXU06_RS15135	COG0783	Belongs to the Dps family
BXU06_RS15140	COG1872	DUF167
BXU06_RS15155	COG3030	protein affecting phage T7 exclusion by the F plasmid
BXU06_RS15160	COG1324	tolerance protein
BXU06_RS15170	COG0697	spore germination
BXU06_RS15195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BXU06_RS15210	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BXU06_RS15215	COG0540	Belongs to the ATCase OTCase family
BXU06_RS15230	COG2319	Wd-40 repeat
BXU06_RS15245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BXU06_RS15255	COG0174	glutamine synthetase
BXU06_RS15260	COG1648	precorrin-2 dehydrogenase activity
BXU06_RS15260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BXU06_RS15285	COG0142	geranyltranstransferase activity
BXU06_RS15310	COG0859	PFAM glycosyl transferase family 9
BXU06_RS15315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BXU06_RS15355	COG2205	protein histidine kinase activity
BXU06_RS15360	COG0745	RESPONSE REGULATOR receiver
BXU06_RS15370	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BXU06_RS15375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BXU06_RS15385	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BXU06_RS15395	COG0463	Glycosyl transferase, family 2
BXU06_RS15400	COG0859	PFAM glycosyl transferase family 9
BXU06_RS15405	COG1519	Transferase
BXU06_RS15425	COG0352	thiamine-phosphate diphosphorylase activity
BXU06_RS15430	COG0351	phosphomethylpyrimidine kinase
BXU06_RS15435	COG1773	rubredoxin
BXU06_RS15440	COG1981	membrane
BXU06_RS15445	COG2954	triphosphatase activity
BXU06_RS15450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BXU06_RS15475	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BXU06_RS15490	COG1794	racemase activity, acting on amino acids and derivatives
BXU06_RS15530	COG1116	anion transmembrane transporter activity
BXU06_RS15535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_RS15550	COG0653	protein targeting
BXU06_RS15560	COG0840	transmembrane signaling receptor activity
BXU06_RS15605	COG1566	PFAM secretion protein HlyD family protein
BXU06_RS15610	COG2814	Major facilitator Superfamily
BXU06_RS15615	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BXU06_RS15630	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BXU06_RS15685	COG2336	PFAM SpoVT AbrB
BXU06_RS15690	COG2337	Toxic component of a toxin-antitoxin (TA) module
BXU06_RS15725	COG2944	sequence-specific DNA binding
BXU06_RS15770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXU06_RS15775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXU06_RS15790	COG0662	Cupin 2, conserved barrel domain protein
BXU06_RS15790	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BXU06_RS15825	COG1091	dTDP-4-dehydrorhamnose reductase activity
BXU06_RS15835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BXU06_RS15840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BXU06_RS15845	COG0126	phosphoglycerate kinase activity
BXU06_RS15855	COG1280	lysine exporter protein (LysE YggA)
BXU06_RS15865	COG0582	viral genome integration into host DNA
BXU06_RS15925	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BXU06_RS15930	COG0242	peptide deformylase activity
BXU06_RS15960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXU06_RS15970	COG1538	Outer membrane efflux protein
BXU06_RS15975	COG1027	Aspartate ammonia-lyase
BXU06_RS15995	COG1116	anion transmembrane transporter activity
BXU06_RS16000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_RS16005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXU06_RS16010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BXU06_RS16015	COG0431	NADPH-dependent FMN reductase
BXU06_RS16020	COG3237	CsbD-like
BXU06_RS16050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BXU06_RS16055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXU06_RS16060	COG1045	serine acetyltransferase
BXU06_RS16075	COG5433	transposase activity
BXU06_RS16090	COG0411	ABC transporter
BXU06_RS16105	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXU06_RS16110	COG3384	dioxygenase
BXU06_RS16130	COG4638	Rieske (2fe-2S)
BXU06_RS16135	COG0583	DNA-binding transcription factor activity
BXU06_RS16140	COG2267	carboxylic ester hydrolase activity
BXU06_RS16145	COG3971	2-oxopent-4-enoate hydratase activity
BXU06_RS16150	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BXU06_RS16155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_RS16160	COG3813	Protein conserved in bacteria
BXU06_RS16185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BXU06_RS16190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_RS16195	COG0840	transmembrane signaling receptor activity
BXU06_RS16205	COG2207	Transcriptional regulator
BXU06_RS16225	COG1538	Outer membrane efflux protein
BXU06_RS16240	COG1309	transcriptional regulator
BXU06_RS16245	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BXU06_RS16265	COG0741	lytic transglycosylase activity
BXU06_RS16275	COG3158	transport of potassium into the cell
BXU06_RS16320	COG0745	RESPONSE REGULATOR receiver
BXU06_RS16330	COG0697	spore germination
BXU06_RS16335	COG1522	sequence-specific DNA binding
BXU06_RS16350	COG0557	exoribonuclease II activity
BXU06_RS16360	COG2922	Belongs to the Smg family
BXU06_RS16365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BXU06_RS16365	COG0758	DNA mediated transformation
BXU06_RS16370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BXU06_RS16375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BXU06_RS16390	COG1187	pseudouridine synthase activity
BXU06_RS16395	COG3781	membrane
BXU06_RS16400	COG0697	spore germination
BXU06_RS16405	COG5433	transposase activity
BXU06_RS16420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BXU06_RS16430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BXU06_RS16440	COG3150	esterase
BXU06_RS16445	COG1448	Aminotransferase
BXU06_RS16450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXU06_RS16455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BXU06_RS16460	COG1333	cytochrome c biogenesis protein
BXU06_RS16470	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BXU06_RS16485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BXU06_RS16490	COG1040	competence protein
BXU06_RS16495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BXU06_RS16500	COG0156	8-amino-7-oxononanoate synthase activity
BXU06_RS16525	COG0762	integral membrane protein
BXU06_RS16530	COG4654	Cytochrome c, class I
BXU06_RS16540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BXU06_RS16565	COG0314	molybdopterin synthase activity
BXU06_RS16570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BXU06_RS16590	COG1136	(ABC) transporter
BXU06_RS16605	COG0840	transmembrane signaling receptor activity
BXU06_RS16620	COG0584	glycerophosphoryl diester phosphodiesterase
BXU06_RS16625	COG0617	tRNA 3'-terminal CCA addition
BXU06_RS16640	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BXU06_RS16645	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BXU06_RS16655	COG0535	radical SAM domain protein
BXU06_RS16660	COG2197	response regulator
BXU06_RS16740	COG1802	Transcriptional regulator
BXU06_RS16775	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BXU06_RS16780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_RS16805	COG4783	chaperone-mediated protein folding
BXU06_RS16820	COG2391	methyltransferase activity
BXU06_RS16840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BXU06_RS16845	COG1984	allophanate hydrolase subunit 2
BXU06_RS16850	COG0288	reversible hydration of carbon dioxide
BXU06_RS16855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BXU06_RS16860	COG0799	negative regulation of ribosome biogenesis
BXU06_RS16865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BXU06_RS16870	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU06_RS16880	COG0840	transmembrane signaling receptor activity
BXU06_RS16885	COG0339	signal peptide processing
BXU06_RS16890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BXU06_RS16905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXU06_RS16925	COG1414	Transcriptional regulator
BXU06_RS16930	COG3384	dioxygenase
BXU06_RS16940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BXU06_RS16950	COG3971	2-oxopent-4-enoate hydratase activity
BXU06_RS16955	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BXU06_RS16960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_RS16965	COG0411	ABC transporter
BXU06_RS16975	COG2267	carboxylic ester hydrolase activity
BXU06_RS16985	COG0840	transmembrane signaling receptor activity
BXU06_RS17000	COG2814	Major facilitator Superfamily
BXU06_RS17005	COG0840	transmembrane signaling receptor activity
BXU06_RS17010	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_RS17015	COG0531	amino acid
BXU06_RS17030	COG0675	Transposase, IS605 OrfB family
BXU06_RS17035	COG2207	Transcriptional regulator
BXU06_RS17055	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BXU06_RS17060	COG1074	ATP-dependent DNA helicase activity
BXU06_RS17065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BXU06_RS17070	COG2200	EAL domain
BXU06_RS17070	COG2199	diguanylate cyclase activity
BXU06_RS17075	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BXU06_RS17080	COG3047	cAMP biosynthetic process
BXU06_RS17090	COG0009	L-threonylcarbamoyladenylate synthase
BXU06_RS17110	COG3039	Transposase
BXU06_RS17120	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BXU06_RS17125	COG0706	membrane insertase activity
BXU06_RS17130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BXU06_RS17135	COG0594	ribonuclease P activity
BXU06_RS17140	COG0230	Belongs to the bacterial ribosomal protein bL34 family