locus-tag	class	description
DLM_RS00005	COG1216	Glycosyl transferase, family 2
DLM_RS00005	COG0438	transferase activity, transferring glycosyl groups
DLM_RS00010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DLM_RS00045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DLM_RS00050	COG2084	Dehydrogenase
DLM_RS00055	COG3813	Protein conserved in bacteria
DLM_RS00080	COG1561	YicC-like family, N-terminal region
DLM_RS00085	COG1357	PFAM Pentapeptide repeats (8 copies)
DLM_RS00085	COG0515	serine threonine protein kinase
DLM_RS00090	COG0631	protein serine/threonine phosphatase activity
DLM_RS00095	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DLM_RS00100	COG3591	Belongs to the peptidase S1B family
DLM_RS00110	COG2205	protein histidine kinase activity
DLM_RS00115	COG0745	RESPONSE REGULATOR receiver
DLM_RS00120	COG0840	transmembrane signaling receptor activity
DLM_RS00125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DLM_RS00145	COG0109	protoheme IX farnesyltransferase activity
DLM_RS00180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DLM_RS00185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DLM_RS00210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DLM_RS00215	COG0306	phosphate transporter
DLM_RS00220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DLM_RS00235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DLM_RS00240	COG0149	triose-phosphate isomerase activity
DLM_RS00245	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DLM_RS00255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DLM_RS00260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DLM_RS00265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DLM_RS00270	COG0649	NAD binding
DLM_RS00275	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DLM_RS00285	COG1034	ATP synthesis coupled electron transport
DLM_RS00290	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DLM_RS00295	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DLM_RS00305	COG0713	ATP synthesis coupled electron transport
DLM_RS00320	COG1007	ATP synthesis coupled electron transport
DLM_RS00330	COG1560	Kdo2-lipid A biosynthetic process
DLM_RS00340	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DLM_RS00345	COG0004	ammonium transporteR
DLM_RS00350	COG0347	Belongs to the P(II) protein family
DLM_RS00360	COG0606	chelatase, subunit chli
DLM_RS00370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DLM_RS00390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DLM_RS00400	COG1596	polysaccharide export
DLM_RS00400	COG1555	photosystem II stabilization
DLM_RS00405	COG0415	Belongs to the DNA photolyase family
DLM_RS00430	COG0237	dephospho-CoA kinase activity
DLM_RS00435	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DLM_RS00440	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DLM_RS00445	COG0860	N-Acetylmuramoyl-L-alanine amidase
DLM_RS00450	COG0802	atpase or kinase
DLM_RS00465	COG2030	dehydratase
DLM_RS00480	COG1960	acyl-CoA dehydrogenase activity
DLM_RS00510	COG1534	Rna-binding protein
DLM_RS00515	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DLM_RS00520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DLM_RS00530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DLM_RS00535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DLM_RS00540	COG0586	Pfam SNARE associated Golgi protein
DLM_RS00555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DLM_RS00565	COG0386	Belongs to the glutathione peroxidase family
DLM_RS00570	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DLM_RS00580	COG0543	2 iron, 2 sulfur cluster binding
DLM_RS00580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLM_RS00595	COG2235	arginine
DLM_RS00600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DLM_RS00615	COG1695	Transcriptional regulator
DLM_RS00625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DLM_RS00630	COG2252	PERMEase
DLM_RS00635	COG0194	GDP metabolic process
DLM_RS00640	COG1758	RNA polymerase activity
DLM_RS00645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DLM_RS00655	COG2022	thiamine diphosphate biosynthetic process
DLM_RS00660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DLM_RS00685	COG1301	dicarboxylic acid transport
DLM_RS00705	COG0840	transmembrane signaling receptor activity
DLM_RS00710	COG0583	DNA-binding transcription factor activity
DLM_RS00730	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DLM_RS00750	COG0583	DNA-binding transcription factor activity
DLM_RS00770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DLM_RS00775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DLM_RS00790	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DLM_RS00800	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DLM_RS00820	COG2264	protein methyltransferase activity
DLM_RS00825	COG0439	Biotin carboxylase
DLM_RS00830	COG0511	ligase activity, forming carbon-carbon bonds
DLM_RS00835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DLM_RS00840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DLM_RS00850	COG2226	methyltransferase
DLM_RS00865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DLM_RS00880	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS00885	COG2610	gluconate transmembrane transporter activity
DLM_RS00905	COG0436	Aminotransferase
DLM_RS00940	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DLM_RS00945	COG0513	Belongs to the DEAD box helicase family
DLM_RS00955	COG1139	Iron-sulfur cluster binding protein
DLM_RS00960	COG0247	lactate metabolic process
DLM_RS00985	COG3276	selenocysteine insertion sequence binding
DLM_RS00995	COG3136	membrane protein required for alginate biosynthesis
DLM_RS01010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DLM_RS01020	COG2201	protein-glutamate methylesterase activity
DLM_RS01025	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DLM_RS01030	COG0835	chemotaxis
DLM_RS01045	COG2198	Histidine kinase
DLM_RS01045	COG0643	Histidine kinase
DLM_RS01065	COG2864	formate dehydrogenase
DLM_RS01070	COG0437	4 iron, 4 sulfur cluster binding
DLM_RS01080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DLM_RS01085	COG0527	aspartate kinase activity
DLM_RS01110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DLM_RS01125	COG0488	(ABC) transporter
DLM_RS01140	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DLM_RS01145	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DLM_RS01145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DLM_RS01150	COG0793	Belongs to the peptidase S41A family
DLM_RS01155	COG4942	peptidase
DLM_RS01160	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DLM_RS01180	COG0811	peptide transport
DLM_RS01185	COG0848	biopolymer transport protein
DLM_RS01190	COG1663	tetraacyldisaccharide 4'-kinase activity
DLM_RS01195	COG2835	tetraacyldisaccharide 4'-kinase activity
DLM_RS01200	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DLM_RS01205	COG0563	adenylate kinase activity
DLM_RS01210	COG1272	protein, Hemolysin III
DLM_RS01215	COG3437	response regulator, receiver
DLM_RS01215	COG0784	Response regulator, receiver
DLM_RS01220	COG4191	Histidine kinase
DLM_RS01220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS01230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DLM_RS01230	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DLM_RS01240	COG1660	Displays ATPase and GTPase activities
DLM_RS01245	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DLM_RS01255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DLM_RS01260	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DLM_RS01265	COG1137	ATPase activity
DLM_RS01270	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DLM_RS01280	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DLM_RS01305	COG2957	Belongs to the agmatine deiminase family
DLM_RS01315	COG0154	amidase activity
DLM_RS01330	COG1902	pentaerythritol trinitrate reductase activity
DLM_RS01330	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLM_RS01340	COG0667	Aldo Keto reductase
DLM_RS01355	COG0330	HflC and HflK could
DLM_RS01360	COG0330	HflC and HflK could
DLM_RS01365	COG1914	H( )-stimulated, divalent metal cation uptake system
DLM_RS01370	COG0861	Integral membrane protein TerC family
DLM_RS01385	COG3842	ATPase activity
DLM_RS01405	COG2188	Transcriptional regulator
DLM_RS01420	COG0252	asparaginase activity
DLM_RS01440	COG0613	PHP domain protein
DLM_RS01445	COG0009	L-threonylcarbamoyladenylate synthase
DLM_RS01450	COG1994	Peptidase M50
DLM_RS01455	COG0180	Tryptophanyl-tRNA synthetase
DLM_RS01465	COG0583	DNA-binding transcription factor activity
DLM_RS01470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DLM_RS01475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DLM_RS01480	COG1187	pseudouridine synthase activity
DLM_RS01500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_RS01505	COG0583	DNA-binding transcription factor activity
DLM_RS01510	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DLM_RS01520	COG0850	regulation of cytokinetic process
DLM_RS01535	COG0583	DNA-binding transcription factor activity
DLM_RS01545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DLM_RS01550	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DLM_RS01575	COG1199	ATP-dependent helicase activity
DLM_RS01575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DLM_RS01580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DLM_RS01585	COG1191	sigma factor activity
DLM_RS01600	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DLM_RS01605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DLM_RS01610	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DLM_RS01625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DLM_RS01630	COG0402	S-adenosylhomocysteine deaminase activity
DLM_RS01725	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DLM_RS01735	COG0039	L-malate dehydrogenase activity
DLM_RS01740	COG2188	Transcriptional regulator
DLM_RS01745	COG2009	succinate dehydrogenase
DLM_RS01755	COG1053	succinate dehydrogenase
DLM_RS01760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DLM_RS01765	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DLM_RS01775	COG0567	Dehydrogenase, E1 component
DLM_RS01780	COG0508	dehydrogenase complex catalyzes the overall conversion of
DLM_RS01790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DLM_RS01795	COG0045	succinate-CoA ligase (ADP-forming) activity
DLM_RS01815	COG0583	DNA-binding transcription factor activity
DLM_RS01820	COG1380	Effector of murein hydrolase LrgA
DLM_RS01835	COG1607	acyl-coa hydrolase
DLM_RS01840	COG0564	pseudouridine synthase activity
DLM_RS01855	COG0463	Glycosyl transferase, family 2
DLM_RS01860	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DLM_RS01865	COG3104	oligopeptide transport
DLM_RS01870	COG3033	Beta-eliminating lyase
DLM_RS01905	COG3278	Belongs to the heme-copper respiratory oxidase family
DLM_RS01915	COG0308	aminopeptidase N
DLM_RS01930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DLM_RS01945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DLM_RS01955	COG2169	Transcriptional regulator
DLM_RS01955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DLM_RS01965	COG0310	cobalt ion transport
DLM_RS01970	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DLM_RS01980	COG1122	ATPase activity
DLM_RS02065	COG0436	Aminotransferase
DLM_RS02070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DLM_RS02080	COG0516	GMP reductase activity
DLM_RS02095	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DLM_RS02100	COG0489	protein tyrosine kinase activity
DLM_RS02110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DLM_RS02110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DLM_RS02130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DLM_RS02135	COG3022	response to hydroperoxide
DLM_RS02145	COG1490	D-aminoacyl-tRNA deacylase activity
DLM_RS02150	COG1388	LysM domain
DLM_RS02150	COG0741	lytic transglycosylase activity
DLM_RS02155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DLM_RS02160	COG2226	methyltransferase
DLM_RS02165	COG0328	RNA-DNA hybrid ribonuclease activity
DLM_RS02175	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DLM_RS02180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DLM_RS02185	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DLM_RS02190	COG0704	Plays a role in the regulation of phosphate uptake
DLM_RS02195	COG0248	Ppx GppA phosphatase
DLM_RS02200	COG0598	Magnesium transport protein CorA
DLM_RS02225	COG0765	amino acid transport
DLM_RS02230	COG0765	amino acid transport
DLM_RS02235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS02240	COG3639	organic phosphonate transmembrane transporter activity
DLM_RS02250	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DLM_RS02255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DLM_RS02260	COG0129	dihydroxy-acid dehydratase activity
DLM_RS02265	COG0625	glutathione transferase activity
DLM_RS02275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DLM_RS02280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DLM_RS02285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DLM_RS02285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DLM_RS02295	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DLM_RS02330	COG0322	excinuclease ABC activity
DLM_RS02335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DLM_RS02370	COG3188	usher protein
DLM_RS02375	COG3121	Chaperone
DLM_RS02380	COG3539	Fimbrial protein
DLM_RS02395	COG1448	Aminotransferase
DLM_RS02410	COG1929	Belongs to the glycerate kinase type-1 family
DLM_RS02420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DLM_RS02435	COG3012	SEC-C Motif Domain Protein
DLM_RS02445	COG0717	Belongs to the dCTP deaminase family
DLM_RS02455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DLM_RS02460	COG0167	dihydroorotate dehydrogenase activity
DLM_RS02465	COG3384	dioxygenase
DLM_RS02480	COG2974	May be involved in recombination
DLM_RS02505	COG1733	regulation of RNA biosynthetic process
DLM_RS02510	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS02525	COG1538	Outer membrane efflux protein
DLM_RS02545	COG1309	transcriptional regulator
DLM_RS02555	COG0583	DNA-binding transcription factor activity
DLM_RS02560	COG1979	alcohol dehydrogenase
DLM_RS02565	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS02570	COG0702	epimerase
DLM_RS02580	COG0656	L-ascorbic acid biosynthetic process
DLM_RS02590	COG0477	Major facilitator Superfamily
DLM_RS02595	COG4221	oxidoreductase activity
DLM_RS02600	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS02610	COG1733	regulation of RNA biosynthetic process
DLM_RS02615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_RS02620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_RS02645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DLM_RS02650	COG3237	CsbD-like
DLM_RS02680	COG0583	DNA-binding transcription factor activity
DLM_RS02685	COG1047	Peptidyl-prolyl cis-trans
DLM_RS02690	COG1522	sequence-specific DNA binding
DLM_RS02700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_RS02705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_RS02725	COG0673	inositol 2-dehydrogenase activity
DLM_RS02730	COG0673	inositol 2-dehydrogenase activity
DLM_RS02745	COG3962	Belongs to the TPP enzyme family
DLM_RS02760	COG1129	ABC transporter
DLM_RS02765	COG1172	Belongs to the binding-protein-dependent transport system permease family
DLM_RS02790	COG3718	enzyme involved in inositol metabolism
DLM_RS02805	COG0105	UTP biosynthetic process
DLM_RS02810	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DLM_RS02820	COG1426	Protein conserved in bacteria
DLM_RS02825	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DLM_RS02830	COG0124	histidyl-tRNA synthetase
DLM_RS02845	COG1160	GTP binding
DLM_RS02850	COG1923	regulation of RNA biosynthetic process
DLM_RS02855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DLM_RS02860	COG0330	HflC and HflK could
DLM_RS02865	COG0330	HflC and HflK could
DLM_RS02870	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DLM_RS02875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DLM_RS02880	COG0673	inositol 2-dehydrogenase activity
DLM_RS02885	COG4702	Belongs to the UPF0303 family
DLM_RS02890	COG1858	cytochrome C peroxidase
DLM_RS02900	COG0477	Major facilitator Superfamily
DLM_RS02920	COG0557	exoribonuclease II activity
DLM_RS02950	COG2205	protein histidine kinase activity
DLM_RS02960	COG2204	response regulator
DLM_RS02975	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DLM_RS02975	COG0506	proline dehydrogenase activity
DLM_RS02975	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DLM_RS03000	COG2205	protein histidine kinase activity
DLM_RS03000	COG0784	Response regulator, receiver
DLM_RS03000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS03000	COG2198	Histidine kinase
DLM_RS03005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLM_RS03010	COG1960	acyl-CoA dehydrogenase activity
DLM_RS03030	COG3971	2-oxopent-4-enoate hydratase activity
DLM_RS03040	COG2814	Major facilitator Superfamily
DLM_RS03050	COG3384	dioxygenase
DLM_RS03055	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS03075	COG2207	Transcriptional regulator
DLM_RS03080	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS03095	COG1113	amino acid transport
DLM_RS03105	COG1846	Transcriptional regulator
DLM_RS03115	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS03130	COG4166	transmembrane transport
DLM_RS03135	COG4174	ABC transporter (Permease)
DLM_RS03140	COG4239	(ABC) transporter, permease
DLM_RS03145	COG4172	Belongs to the ABC transporter superfamily
DLM_RS03155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DLM_RS03195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DLM_RS03200	COG0534	Mate efflux family protein
DLM_RS03215	COG0617	tRNA 3'-terminal CCA addition
DLM_RS03230	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DLM_RS03235	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DLM_RS03240	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DLM_RS03250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DLM_RS03255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DLM_RS03260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DLM_RS03265	COG4658	electron transport chain
DLM_RS03280	COG2878	Part of a membrane complex involved in electron transport
DLM_RS03295	COG3781	membrane
DLM_RS03300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DLM_RS03310	COG3162	membrane
DLM_RS03315	COG0583	DNA-binding transcription factor activity
DLM_RS03325	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DLM_RS03330	COG4948	Mandelate Racemase Muconate Lactonizing
DLM_RS03335	COG1063	alcohol dehydrogenase
DLM_RS03340	COG0477	Major facilitator Superfamily
DLM_RS03345	COG0246	Mannitol dehydrogenase
DLM_RS03350	COG1802	Transcriptional regulator
DLM_RS03355	COG1620	l-lactate permease
DLM_RS03360	COG0840	transmembrane signaling receptor activity
DLM_RS03365	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLM_RS03385	COG0659	secondary active sulfate transmembrane transporter activity
DLM_RS03390	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DLM_RS03395	COG1032	radical SAM domain protein
DLM_RS03405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DLM_RS03410	COG0205	6-phosphofructokinase activity
DLM_RS03415	COG0215	cysteine-tRNA ligase activity
DLM_RS03420	COG0254	rRNA binding
DLM_RS03435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DLM_RS03455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DLM_RS03460	COG1960	acyl-CoA dehydrogenase activity
DLM_RS03470	COG0318	PFAM AMP-dependent synthetase and ligase
DLM_RS03475	COG3318	Belongs to the UPF0149 family
DLM_RS03475	COG3012	SEC-C Motif Domain Protein
DLM_RS03485	COG4948	Mandelate Racemase Muconate Lactonizing
DLM_RS03490	COG3254	rhamnose metabolic process
DLM_RS03495	COG3618	amidohydrolase
DLM_RS03515	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS03520	COG1960	acyl-CoA dehydrogenase activity
DLM_RS03540	COG2766	serine protein kinase
DLM_RS03545	COG2718	Belongs to the UPF0229 family
DLM_RS03550	COG2719	SpoVR family
DLM_RS03555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DLM_RS03560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DLM_RS03570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DLM_RS03575	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DLM_RS03585	COG0167	dihydroorotate dehydrogenase activity
DLM_RS03595	COG1360	Flagellar Motor Protein
DLM_RS03610	COG0546	phosphoglycolate phosphatase activity
DLM_RS03620	COG1530	ribonuclease E activity
DLM_RS03630	COG0583	DNA-binding transcription factor activity
DLM_RS03635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DLM_RS03640	COG3842	ATPase activity
DLM_RS03645	COG1176	ABC-type spermidine putrescine transport system, permease component I
DLM_RS03650	COG1177	transmembrane transport
DLM_RS03655	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS03685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DLM_RS03690	COG1376	ErfK ybiS ycfS ynhG family protein
DLM_RS03695	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DLM_RS03700	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DLM_RS03720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DLM_RS03745	COG3423	Transcriptional regulator
DLM_RS03810	COG0776	regulation of translation
DLM_RS03850	COG3023	N-Acetylmuramoyl-L-alanine amidase
DLM_RS03890	COG4373	Mu-like prophage FluMu protein gp28
DLM_RS03895	COG4383	Mu-like prophage protein gp29
DLM_RS03940	COG4387	Mu-like prophage protein GP36
DLM_RS04050	COG1562	ergosterol biosynthetic process
DLM_RS04060	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DLM_RS04065	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS04080	COG1595	DNA-templated transcription, initiation
DLM_RS04105	COG0791	NLP P60 protein
DLM_RS04120	COG1136	(ABC) transporter
DLM_RS04125	COG3264	Mechanosensitive ion channel
DLM_RS04125	COG1511	domain protein
DLM_RS04130	COG4566	intracellular signal transduction
DLM_RS04145	COG0671	phosphoesterase, PA-phosphatase related
DLM_RS04160	COG3568	Endonuclease Exonuclease Phosphatase
DLM_RS04165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DLM_RS04170	COG2011	ABC-type metal ion transport system permease component
DLM_RS04175	COG1464	Belongs to the NlpA lipoprotein family
DLM_RS04185	COG1418	mRNA catabolic process
DLM_RS04190	COG2313	pseudouridylate synthase activity
DLM_RS04195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DLM_RS04195	COG1522	sequence-specific DNA binding
DLM_RS04205	COG4178	(ABC) transporter
DLM_RS04215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLM_RS04220	COG2990	Protein conserved in bacteria
DLM_RS04230	COG0280	phosphate acetyltransferase
DLM_RS04230	COG0281	malic enzyme
DLM_RS04255	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DLM_RS04285	COG4191	Histidine kinase
DLM_RS04305	COG4215	(ABC) transporter
DLM_RS04320	COG2902	Dehydrogenase
DLM_RS04330	COG0697	spore germination
DLM_RS04430	COG4383	Mu-like prophage protein gp29
DLM_RS04435	COG4373	Mu-like prophage FluMu protein gp28
DLM_RS04475	COG3023	N-Acetylmuramoyl-L-alanine amidase
DLM_RS04545	COG2801	Transposase and inactivated derivatives
DLM_RS04555	COG3423	Transcriptional regulator
DLM_RS04560	COG2932	Transcriptional regulator
DLM_RS04590	COG3179	chitinase
DLM_RS04620	COG1960	acyl-CoA dehydrogenase activity
DLM_RS04640	COG1858	cytochrome C peroxidase
DLM_RS04645	COG0488	(ABC) transporter
DLM_RS04675	COG1881	PFAM PEBP family protein
DLM_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS04690	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS04720	COG4774	siderophore transport
DLM_RS04725	COG2819	hydrolase of the alpha beta superfamily
DLM_RS04745	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DLM_RS04750	COG0745	RESPONSE REGULATOR receiver
DLM_RS04755	COG0784	Response regulator, receiver
DLM_RS04755	COG0835	chemotaxis
DLM_RS04760	COG0784	Response regulator, receiver
DLM_RS04760	COG0835	chemotaxis
DLM_RS04775	COG4302	ethanolamine ammonia-lyase activity
DLM_RS04780	COG4303	Ethanolamine ammonia lyase large subunit
DLM_RS04785	COG0531	amino acid
DLM_RS04795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_RS04835	COG1686	Belongs to the peptidase S11 family
DLM_RS04840	COG0556	nucleotide-excision repair
DLM_RS04850	COG0583	DNA-binding transcription factor activity
DLM_RS04865	COG0840	transmembrane signaling receptor activity
DLM_RS04880	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
DLM_RS04885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DLM_RS04890	COG2201	protein-glutamate methylesterase activity
DLM_RS04900	COG1677	Flagellar hook-basal body complex protein FliE
DLM_RS04905	COG1766	The M ring may be actively involved in energy transduction
DLM_RS04920	COG1157	protein secretion by the type III secretion system
DLM_RS04930	COG3842	ATPase activity
DLM_RS04960	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DLM_RS04980	COG1987	bacterial-type flagellum assembly
DLM_RS04985	COG1684	flagellar biosynthetic protein fliR
DLM_RS04990	COG0217	transcriptional regulatory protein
DLM_RS04995	COG0006	proline dipeptidase activity
DLM_RS05000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLM_RS05005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLM_RS05010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DLM_RS05025	COG0686	Belongs to the AlaDH PNT family
DLM_RS05040	COG0583	DNA-binding transcription factor activity
DLM_RS05045	COG0501	Belongs to the peptidase M48B family
DLM_RS05055	COG0038	chloride channel
DLM_RS05060	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS05065	COG2223	nitrite transmembrane transporter activity
DLM_RS05070	COG4948	Mandelate Racemase Muconate Lactonizing
DLM_RS05090	COG2134	cdp-diacylglycerol pyrophosphatase
DLM_RS05095	COG2814	Major facilitator Superfamily
DLM_RS05130	COG0583	DNA-binding transcription factor activity
DLM_RS05135	COG1349	DNA-binding transcription factor activity
DLM_RS05150	COG0183	Belongs to the thiolase family
DLM_RS05160	COG2271	Major facilitator Superfamily
DLM_RS05165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DLM_RS05175	COG2356	endonuclease I
DLM_RS05190	COG1181	Belongs to the D-alanine--D-alanine ligase family
DLM_RS05195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DLM_RS05200	COG0745	RESPONSE REGULATOR receiver
DLM_RS05205	COG2205	protein histidine kinase activity
DLM_RS05210	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DLM_RS05215	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DLM_RS05220	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DLM_RS05235	COG0730	response to heat
DLM_RS05250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS05250	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DLM_RS05255	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DLM_RS05270	COG0542	response to heat
DLM_RS05295	COG0791	NLP P60 protein
DLM_RS05300	COG0488	(ABC) transporter
DLM_RS05315	COG0285	dihydrofolate synthase activity
DLM_RS05320	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
DLM_RS05325	COG1286	toxin biosynthetic process
DLM_RS05345	COG1960	acyl-CoA dehydrogenase activity
DLM_RS05360	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLM_RS05360	COG1024	Enoyl-CoA hydratase
DLM_RS05365	COG0183	Belongs to the thiolase family
DLM_RS05375	COG1752	Esterase of the alpha-beta hydrolase superfamily
DLM_RS05380	COG0134	indole-3-glycerol-phosphate synthase activity
DLM_RS05385	COG0429	hydrolase of the alpha beta-hydrolase fold
DLM_RS05390	COG0521	Mo-molybdopterin cofactor biosynthetic process
DLM_RS05395	COG3028	Belongs to the UPF0307 family
DLM_RS05400	COG0312	modulator of DNA gyrase
DLM_RS05410	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DLM_RS05475	COG0825	malonyl-CoA metabolic process
DLM_RS05480	COG0037	tRNA processing
DLM_RS05495	COG0544	peptidyl-prolyl cis-trans isomerase activity
DLM_RS05500	COG0740	serine-type endopeptidase activity
DLM_RS05505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DLM_RS05510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DLM_RS05530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLM_RS05535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DLM_RS05540	COG2081	HI0933 family
DLM_RS05550	COG3411	Ferredoxin
DLM_RS05560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DLM_RS05565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DLM_RS05570	COG0024	Methionine aminopeptidase
DLM_RS05585	COG1199	ATP-dependent helicase activity
DLM_RS05595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DLM_RS05600	COG0137	argininosuccinate synthase activity
DLM_RS05610	COG1280	lysine exporter protein (LysE YggA)
DLM_RS05620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DLM_RS05625	COG1454	alcohol dehydrogenase
DLM_RS05640	COG0837	glucose binding
DLM_RS05640	COG1737	Transcriptional regulator
DLM_RS05645	COG1666	GTP binding
DLM_RS05650	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DLM_RS05660	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS05665	COG1396	sequence-specific DNA binding
DLM_RS05665	COG1917	Cupin 2, conserved barrel domain protein
DLM_RS05670	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DLM_RS05675	COG0174	glutamine synthetase
DLM_RS05690	COG1360	Flagellar Motor Protein
DLM_RS05705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DLM_RS05720	COG0617	tRNA 3'-terminal CCA addition
DLM_RS05730	COG0741	lytic transglycosylase activity
DLM_RS05730	COG1196	nuclear chromosome segregation
DLM_RS05730	COG0739	heme binding
DLM_RS05750	COG0546	phosphoglycolate phosphatase activity
DLM_RS05755	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS05760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DLM_RS05765	COG2967	ApaG domain
DLM_RS05770	COG5265	(ABC) transporter
DLM_RS05775	COG5001	Diguanylate cyclase
DLM_RS05775	COG5002	protein histidine kinase activity
DLM_RS05785	COG2195	Cleaves the N-terminal amino acid of tripeptides
DLM_RS05790	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DLM_RS05795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DLM_RS05825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DLM_RS05830	COG0733	neurotransmitter:sodium symporter activity
DLM_RS05840	COG2818	Glycosylase
DLM_RS05845	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DLM_RS05850	COG2833	Protein of unknown function (DUF455)
DLM_RS05865	COG0826	peptidase U32
DLM_RS05875	COG1176	ABC-type spermidine putrescine transport system, permease component I
DLM_RS05880	COG1177	transmembrane transport
DLM_RS05895	COG0018	arginyl-trna synthetase
DLM_RS05900	COG0006	proline dipeptidase activity
DLM_RS05905	COG0513	Belongs to the DEAD box helicase family
DLM_RS05910	COG3622	Belongs to the hyi family
DLM_RS05920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DLM_RS05940	COG0735	belongs to the Fur family
DLM_RS05945	COG0523	cobalamin synthesis protein
DLM_RS05955	COG1121	(ABC) transporter
DLM_RS05960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DLM_RS05965	COG0803	Belongs to the bacterial solute-binding protein 9 family
DLM_RS05975	COG1024	Enoyl-CoA hydratase
DLM_RS05980	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DLM_RS05990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DLM_RS06000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DLM_RS06010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DLM_RS06010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DLM_RS06085	COG0667	Aldo Keto reductase
DLM_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS06100	COG1309	transcriptional regulator
DLM_RS06110	COG0583	DNA-binding transcription factor activity
DLM_RS06115	COG1979	alcohol dehydrogenase
DLM_RS06120	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS06125	COG0702	epimerase
DLM_RS06135	COG0656	L-ascorbic acid biosynthetic process
DLM_RS06140	COG0183	Belongs to the thiolase family
DLM_RS06150	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS06155	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS06165	COG1733	regulation of RNA biosynthetic process
DLM_RS06170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_RS06175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_RS06200	COG1764	response to oxidative stress
DLM_RS06220	COG0835	chemotaxis
DLM_RS06230	COG0840	transmembrane signaling receptor activity
DLM_RS06240	COG2201	protein-glutamate methylesterase activity
DLM_RS06250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DLM_RS06255	COG0745	RESPONSE REGULATOR receiver
DLM_RS06260	COG2198	Histidine kinase
DLM_RS06260	COG0643	Histidine kinase
DLM_RS06270	COG0745	RESPONSE REGULATOR receiver
DLM_RS06275	COG0840	transmembrane signaling receptor activity
DLM_RS06280	COG5002	protein histidine kinase activity
DLM_RS06280	COG2205	protein histidine kinase activity
DLM_RS06280	COG0784	Response regulator, receiver
DLM_RS06290	COG0270	DNA (cytosine-5-)-methyltransferase activity
DLM_RS06395	COG4397	Mu-like prophage major head subunit gpT
DLM_RS06420	COG2369	cell adhesion
DLM_RS06425	COG4383	Mu-like prophage protein gp29
DLM_RS06505	COG0776	regulation of translation
DLM_RS06555	COG3423	Transcriptional regulator
DLM_RS06650	COG0270	DNA (cytosine-5-)-methyltransferase activity
DLM_RS06680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLM_RS06715	COG1917	Cupin 2, conserved barrel domain protein
DLM_RS06715	COG2169	Transcriptional regulator
DLM_RS06735	COG2205	protein histidine kinase activity
DLM_RS06790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DLM_RS06815	COG0640	Transcriptional regulator
DLM_RS06840	COG2814	Major facilitator Superfamily
DLM_RS06860	COG1764	response to oxidative stress
DLM_RS06875	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DLM_RS06880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DLM_RS06890	COG0840	transmembrane signaling receptor activity
DLM_RS06895	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DLM_RS06900	COG4266	Belongs to the allantoicase family
DLM_RS06905	COG4598	ABC transporter
DLM_RS06910	COG0765	amino acid transport
DLM_RS06915	COG0765	amino acid transport
DLM_RS06925	COG2188	Transcriptional regulator
DLM_RS06935	COG0559	Belongs to the binding-protein-dependent transport system permease family
DLM_RS06970	COG0804	urea catabolic process
DLM_RS06975	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DLM_RS06980	COG0830	nickel cation binding
DLM_RS06985	COG0454	-acetyltransferase
DLM_RS06990	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DLM_RS07000	COG5002	protein histidine kinase activity
DLM_RS07000	COG2198	Histidine kinase
DLM_RS07000	COG0784	Response regulator, receiver
DLM_RS07005	COG1126	abc transporter atp-binding protein
DLM_RS07015	COG2072	flavoprotein involved in K transport
DLM_RS07035	COG0411	ABC transporter
DLM_RS07055	COG0601	transmembrane transport
DLM_RS07060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DLM_RS07065	COG0444	Belongs to the ABC transporter superfamily
DLM_RS07070	COG4608	Belongs to the ABC transporter superfamily
DLM_RS07090	COG2814	Major facilitator Superfamily
DLM_RS07135	COG0583	DNA-binding transcription factor activity
DLM_RS07140	COG2814	Major facilitator Superfamily
DLM_RS07150	COG1760	l-serine dehydratase
DLM_RS07160	COG0583	DNA-binding transcription factor activity
DLM_RS07165	COG2040	homocysteine
DLM_RS07175	COG4521	taurine ABC transporter
DLM_RS07180	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DLM_RS07185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DLM_RS07190	COG2175	clavaminate synthase activity
DLM_RS07195	COG0513	Belongs to the DEAD box helicase family
DLM_RS07200	COG0840	transmembrane signaling receptor activity
DLM_RS07215	COG0583	DNA-binding transcription factor activity
DLM_RS07225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS07240	COG0688	phosphatidylethanolamine metabolic process
DLM_RS07285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DLM_RS07295	COG0481	GTPase activity
DLM_RS07310	COG0571	ribonuclease III activity
DLM_RS07315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DLM_RS07325	COG1381	Involved in DNA repair and RecF pathway recombination
DLM_RS07330	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DLM_RS07335	COG0736	holo-[acyl-carrier-protein] synthase activity
DLM_RS07340	COG1472	Belongs to the glycosyl hydrolase 3 family
DLM_RS07350	COG3437	response regulator, receiver
DLM_RS07350	COG2770	Histidine kinase
DLM_RS07355	COG1643	Atp-dependent helicase
DLM_RS07360	COG0840	transmembrane signaling receptor activity
DLM_RS07375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DLM_RS07430	COG1619	proteins homologs of microcin C7 resistance protein MccF
DLM_RS07440	COG0175	sulfate reduction
DLM_RS07445	COG2895	sulfate adenylyltransferase (ATP) activity
DLM_RS07460	COG0523	cobalamin synthesis protein
DLM_RS07465	COG2431	L-lysine efflux transmembrane transporter activity
DLM_RS07480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DLM_RS07485	COG0564	pseudouridine synthase activity
DLM_RS07490	COG1744	ABC transporter substrate-binding protein PnrA-like
DLM_RS07495	COG3845	ABC transporter
DLM_RS07500	COG4603	Belongs to the binding-protein-dependent transport system permease family
DLM_RS07505	COG1079	Belongs to the binding-protein-dependent transport system permease family
DLM_RS07525	COG0840	transmembrane signaling receptor activity
DLM_RS07555	COG1294	oxidase, subunit
DLM_RS07565	COG0583	DNA-binding transcription factor activity
DLM_RS07570	COG4221	oxidoreductase activity
DLM_RS07605	COG2423	ornithine cyclodeaminase activity
DLM_RS07610	COG2186	Transcriptional regulator
DLM_RS07650	COG2011	ABC-type metal ion transport system permease component
DLM_RS07675	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS07695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DLM_RS07705	COG0531	amino acid
DLM_RS07720	COG1129	ABC transporter
DLM_RS07725	COG1172	Belongs to the binding-protein-dependent transport system permease family
DLM_RS07730	COG1172	Belongs to the binding-protein-dependent transport system permease family
DLM_RS07750	COG2188	Transcriptional regulator
DLM_RS07755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLM_RS07765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLM_RS07775	COG0431	NADPH-dependent FMN reductase
DLM_RS07820	COG3938	Belongs to the proline racemase family
DLM_RS07825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DLM_RS07835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS07850	COG0473	3-isopropylmalate dehydrogenase activity
DLM_RS07855	COG0583	DNA-binding transcription factor activity
DLM_RS07870	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DLM_RS07875	COG2707	UPF0756 membrane protein
DLM_RS08045	COG1876	peptidase activity
DLM_RS08105	COG1309	transcriptional regulator
DLM_RS08205	COG2831	hemolysin activation secretion protein
DLM_RS08210	COG3210	domain, Protein
DLM_RS08265	COG0497	DNA recombination
DLM_RS08270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DLM_RS08280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DLM_RS08285	COG0123	including yeast histone deacetylase and acetoin utilization protein
DLM_RS08310	COG2197	response regulator
DLM_RS08315	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS08345	COG0583	DNA-binding transcription factor activity
DLM_RS08355	COG2119	membrane
DLM_RS08360	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DLM_RS08370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS08385	COG2824	Alkylphosphonate utilization operon protein PhnA
DLM_RS08390	COG0534	Mate efflux family protein
DLM_RS08425	COG0415	Belongs to the DNA photolyase family
DLM_RS08430	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
DLM_RS08440	COG3040	lipid binding
DLM_RS08445	COG3046	protein related to deoxyribodipyrimidine photolyase
DLM_RS08450	COG0415	Belongs to the DNA photolyase family
DLM_RS08465	COG4221	oxidoreductase activity
DLM_RS08475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DLM_RS08485	COG0493	'glutamate synthase
DLM_RS08490	COG1309	transcriptional regulator
DLM_RS08515	COG0009	L-threonylcarbamoyladenylate synthase
DLM_RS08520	COG3002	Belongs to the UPF0753 family
DLM_RS08525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DLM_RS08530	COG0583	DNA-binding transcription factor activity
DLM_RS08575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_RS08585	COG0745	RESPONSE REGULATOR receiver
DLM_RS08590	COG5002	protein histidine kinase activity
DLM_RS08600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DLM_RS08620	COG0679	Auxin Efflux Carrier
DLM_RS08630	COG1802	Transcriptional regulator
DLM_RS08635	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS08650	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DLM_RS08680	COG3052	prosthetic group binding
DLM_RS08705	COG2200	EAL domain
DLM_RS08705	COG2199	diguanylate cyclase activity
DLM_RS08730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DLM_RS08735	COG1686	Belongs to the peptidase S11 family
DLM_RS08740	COG2921	Belongs to the UPF0250 family
DLM_RS08745	COG0321	lipoyl(octanoyl) transferase activity
DLM_RS08750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DLM_RS08780	COG1278	Cold shock
DLM_RS08790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DLM_RS08795	COG0420	3'-5' exonuclease activity
DLM_RS08800	COG0419	ATPase involved in DNA repair
DLM_RS08830	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DLM_RS08860	COG2217	Heavy metal translocating P-type atpase
DLM_RS08875	COG1217	gtp-binding protein TYPA
DLM_RS08880	COG0747	negative chemotaxis
DLM_RS08890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_RS08910	COG4974	Belongs to the 'phage' integrase family
DLM_RS09030	COG0667	Aldo Keto reductase
DLM_RS09045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DLM_RS09050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DLM_RS09060	COG0739	heme binding
DLM_RS09065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DLM_RS09070	COG1674	ftsk spoiiie
DLM_RS09075	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DLM_RS09090	COG1312	Catalyzes the dehydration of D-mannonate
DLM_RS09095	COG2271	Major facilitator Superfamily
DLM_RS09100	COG0473	3-isopropylmalate dehydrogenase activity
DLM_RS09100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DLM_RS09105	COG2186	Transcriptional regulator
DLM_RS09110	COG1024	Enoyl-CoA hydratase
DLM_RS09125	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DLM_RS09140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DLM_RS09160	COG4122	O-methyltransferase activity
DLM_RS09170	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DLM_RS09200	COG0436	Aminotransferase
DLM_RS09205	COG1522	sequence-specific DNA binding
DLM_RS09220	COG4149	molybdate abc transporter
DLM_RS09225	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DLM_RS09240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DLM_RS09245	COG0513	Belongs to the DEAD box helicase family
DLM_RS09255	COG3437	response regulator, receiver
DLM_RS09260	COG0840	transmembrane signaling receptor activity
DLM_RS09270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DLM_RS09300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DLM_RS09300	COG2199	diguanylate cyclase activity
DLM_RS09305	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DLM_RS09325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLM_RS09330	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DLM_RS09335	COG0174	glutamine synthetase
DLM_RS09350	COG1538	Outer membrane efflux protein
DLM_RS09360	COG2814	Major facilitator Superfamily
DLM_RS09365	COG1538	Outer membrane efflux protein
DLM_RS09370	COG1136	(ABC) transporter
DLM_RS09370	COG0577	efflux transmembrane transporter activity
DLM_RS09375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_RS09385	COG2197	response regulator
DLM_RS09395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DLM_RS09420	COG1335	isochorismatase
DLM_RS09435	COG1741	Belongs to the pirin family
DLM_RS09455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DLM_RS09455	COG0047	phosphoribosylformylglycinamidine synthase activity
DLM_RS09480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DLM_RS09480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DLM_RS09495	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DLM_RS09605	COG3550	peptidyl-serine autophosphorylation
DLM_RS09615	COG3042	response to heat
DLM_RS09630	COG0840	transmembrane signaling receptor activity
DLM_RS09640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS09645	COG0765	amino acid transport
DLM_RS09665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS09670	COG0765	amino acid transport
DLM_RS09675	COG1126	abc transporter atp-binding protein
DLM_RS09695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_RS09705	COG0583	DNA-binding transcription factor activity
DLM_RS09725	COG0243	molybdopterin cofactor binding
DLM_RS09735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DLM_RS09740	COG2223	nitrite transmembrane transporter activity
DLM_RS09745	COG1116	anion transmembrane transporter activity
DLM_RS09745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLM_RS09750	COG3707	response regulator
DLM_RS09770	COG0583	DNA-binding transcription factor activity
DLM_RS09780	COG4191	Histidine kinase
DLM_RS09800	COG0583	DNA-binding transcription factor activity
DLM_RS09855	COG2198	Histidine kinase
DLM_RS09855	COG2205	protein histidine kinase activity
DLM_RS09855	COG0784	Response regulator, receiver
DLM_RS09860	COG2197	response regulator
DLM_RS09865	COG3842	ATPase activity
DLM_RS09875	COG1176	ABC-type spermidine putrescine transport system, permease component I
DLM_RS09880	COG1177	transmembrane transport
DLM_RS09905	COG1763	Mo-molybdopterin cofactor biosynthetic process
DLM_RS09925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DLM_RS09930	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLM_RS09935	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLM_RS09940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DLM_RS09945	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLM_RS09965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DLM_RS09970	COG0575	Belongs to the CDS family
DLM_RS09975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DLM_RS09980	COG0233	cytoplasmic translational termination
DLM_RS09985	COG0528	UMP kinase activity
DLM_RS09990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DLM_RS09995	COG0052	Belongs to the universal ribosomal protein uS2 family
DLM_RS10010	COG0477	Major facilitator Superfamily
DLM_RS10020	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DLM_RS10025	COG2816	NAD+ diphosphatase activity
DLM_RS10035	COG0166	Belongs to the GPI family
DLM_RS10040	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DLM_RS10045	COG0501	Belongs to the peptidase M48B family
DLM_RS10050	COG2154	pterin-4-alpha-carbinolamine dehydratase
DLM_RS10060	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS10065	COG1956	GAF domain-containing protein
DLM_RS10075	COG0745	RESPONSE REGULATOR receiver
DLM_RS10080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DLM_RS10085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DLM_RS10090	COG0443	Heat shock 70 kDa protein
DLM_RS10100	COG2321	neutral zinc metallopeptidase
DLM_RS10105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DLM_RS10115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DLM_RS10120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DLM_RS10130	COG0307	riboflavin synthase, alpha
DLM_RS10135	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DLM_RS10150	COG1063	alcohol dehydrogenase
DLM_RS10155	COG0842	Transport permease protein
DLM_RS10160	COG1129	ABC transporter
DLM_RS10160	COG0842	Transport permease protein
DLM_RS10165	COG1131	(ABC) transporter
DLM_RS10170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_RS10180	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DLM_RS10200	COG5001	Diguanylate cyclase
DLM_RS10200	COG3447	MASE1 domain protein
DLM_RS10200	COG5002	protein histidine kinase activity
DLM_RS10215	COG0583	DNA-binding transcription factor activity
DLM_RS10225	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DLM_RS10245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DLM_RS10250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DLM_RS10255	COG1045	serine acetyltransferase
DLM_RS10270	COG2011	ABC-type metal ion transport system permease component
DLM_RS10275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DLM_RS10290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DLM_RS10295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLM_RS10300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLM_RS10305	COG0431	NADPH-dependent FMN reductase
DLM_RS10315	COG1113	amino acid transport
DLM_RS10350	COG2159	amidohydrolase
DLM_RS10355	COG3384	dioxygenase
DLM_RS10365	COG2828	Protein conserved in bacteria
DLM_RS10370	COG0583	DNA-binding transcription factor activity
DLM_RS10375	COG0583	DNA-binding transcription factor activity
DLM_RS10390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS10405	COG1473	amidohydrolase
DLM_RS10410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLM_RS10415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLM_RS10450	COG0281	malic enzyme
DLM_RS10450	COG0280	phosphate acetyltransferase
DLM_RS10580	COG5005	Phage virion morphogenesis
DLM_RS10590	COG4383	Mu-like prophage protein gp29
DLM_RS10595	COG4373	Mu-like prophage FluMu protein gp28
DLM_RS10635	COG3023	N-Acetylmuramoyl-L-alanine amidase
DLM_RS10675	COG0776	regulation of translation
DLM_RS10725	COG2801	Transposase and inactivated derivatives
DLM_RS10735	COG3423	Transcriptional regulator
DLM_RS10770	COG0450	alkyl hydroperoxide reductase
DLM_RS10775	COG2175	clavaminate synthase activity
DLM_RS10790	COG0477	Major facilitator Superfamily
DLM_RS10805	COG2814	Major facilitator Superfamily
DLM_RS10815	COG1053	succinate dehydrogenase
DLM_RS10820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DLM_RS10825	COG1053	succinate dehydrogenase
DLM_RS10865	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DLM_RS10865	COG1082	Xylose isomerase domain protein TIM barrel
DLM_RS10870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DLM_RS10880	COG1082	Xylose isomerase domain protein TIM barrel
DLM_RS10900	COG0667	Aldo Keto reductase
DLM_RS10930	COG2159	amidohydrolase
DLM_RS10935	COG2828	Protein conserved in bacteria
DLM_RS10945	COG0840	transmembrane signaling receptor activity
DLM_RS10950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DLM_RS10955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DLM_RS10960	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DLM_RS10965	COG0840	transmembrane signaling receptor activity
DLM_RS10980	COG2822	iron ion transport
DLM_RS10985	COG0672	)-iron permease
DLM_RS10990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DLM_RS10995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DLM_RS11000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DLM_RS11005	COG2372	response to copper ion
DLM_RS11010	COG1276	copper resistance
DLM_RS11070	COG0114	fumarate hydratase activity
DLM_RS11075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DLM_RS11085	COG1278	Cold shock
DLM_RS11090	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DLM_RS11100	COG0583	DNA-binding transcription factor activity
DLM_RS11105	COG2814	Major facilitator Superfamily
DLM_RS11110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DLM_RS11115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DLM_RS11120	COG2249	NAD(P)H dehydrogenase (quinone) activity
DLM_RS11145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DLM_RS11150	COG0798	PFAM Bile acid sodium symporter
DLM_RS11165	COG2072	flavoprotein involved in K transport
DLM_RS11175	COG3437	response regulator, receiver
DLM_RS11175	COG4999	Histidine kinase
DLM_RS11175	COG3850	Histidine kinase
DLM_RS11175	COG2205	protein histidine kinase activity
DLM_RS11180	COG1492	cobalamin metabolic process
DLM_RS11185	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DLM_RS11195	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DLM_RS11200	COG3411	Ferredoxin
DLM_RS11225	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DLM_RS11230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DLM_RS11230	COG1648	precorrin-2 dehydrogenase activity
DLM_RS11235	COG2875	Belongs to the precorrin methyltransferase family
DLM_RS11260	COG1797	cobyrinic acid a,c-diamide synthase activity
DLM_RS11265	COG0778	Nitroreductase
DLM_RS11270	COG0583	DNA-binding transcription factor activity
DLM_RS11305	COG0439	Biotin carboxylase
DLM_RS11310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DLM_RS11315	COG1984	allophanate hydrolase subunit 2
DLM_RS11340	COG1289	transmembrane transporter activity
DLM_RS11355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DLM_RS11360	COG2200	EAL domain
DLM_RS11365	COG3123	guanosine phosphorylase activity
DLM_RS11380	COG0412	Dienelactone hydrolase
DLM_RS11385	COG0643	Histidine kinase
DLM_RS11385	COG2198	Histidine kinase
DLM_RS11395	COG1278	Cold shock
DLM_RS11420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DLM_RS11455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DLM_RS11460	COG3706	GGDEF domain
DLM_RS11480	COG2205	protein histidine kinase activity
DLM_RS11485	COG0745	RESPONSE REGULATOR receiver
DLM_RS11495	COG0583	DNA-binding transcription factor activity
DLM_RS11505	COG0312	modulator of DNA gyrase
DLM_RS11510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DLM_RS11520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DLM_RS11535	COG0859	PFAM glycosyl transferase family 9
DLM_RS11540	COG1309	transcriptional regulator
DLM_RS11550	COG0492	ferredoxin-NADP+ reductase activity
DLM_RS11560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DLM_RS11565	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DLM_RS11575	COG2096	Adenosyltransferase
DLM_RS11590	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DLM_RS11605	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DLM_RS11615	COG0840	transmembrane signaling receptor activity
DLM_RS11625	COG1739	Uncharacterized protein family UPF0029
DLM_RS11640	COG2917	probably involved in intracellular septation
DLM_RS11645	COG2350	Protein conserved in bacteria
DLM_RS11655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLM_RS11660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLM_RS11665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DLM_RS11670	COG4589	Belongs to the CDS family
DLM_RS11680	COG2267	carboxylic ester hydrolase activity
DLM_RS11685	COG2453	phosphatase
DLM_RS11685	COG0671	phosphoesterase, PA-phosphatase related
DLM_RS11710	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DLM_RS11715	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DLM_RS11770	COG3210	domain, Protein
DLM_RS11790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLM_RS11795	COG1773	rubredoxin
DLM_RS11825	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DLM_RS11845	COG2204	response regulator
DLM_RS11860	COG2318	DinB family
DLM_RS11865	COG0840	transmembrane signaling receptor activity
DLM_RS11875	COG1215	transferase activity, transferring glycosyl groups
DLM_RS11880	COG0726	polysaccharide deacetylase
DLM_RS11880	COG1649	PFAM Uncharacterised BCR, COG1649
DLM_RS11895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DLM_RS11900	COG1764	response to oxidative stress
DLM_RS11905	COG1917	Cupin 2, conserved barrel domain protein
DLM_RS11905	COG4977	sequence-specific DNA binding
DLM_RS11930	COG2866	Carboxypeptidase
DLM_RS11965	COG1970	mechanosensitive ion channel activity
DLM_RS11995	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS12000	COG2205	protein histidine kinase activity
DLM_RS12000	COG0784	Response regulator, receiver
DLM_RS12015	COG0840	transmembrane signaling receptor activity
DLM_RS12030	COG0583	DNA-binding transcription factor activity
DLM_RS12035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DLM_RS12040	COG1518	maintenance of DNA repeat elements
DLM_RS12055	COG1857	crispr-associated protein
DLM_RS12090	COG0776	regulation of translation
DLM_RS12095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DLM_RS12095	COG0072	phenylalanine-tRNA ligase activity
DLM_RS12100	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DLM_RS12105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DLM_RS12110	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DLM_RS12115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DLM_RS12120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DLM_RS12135	COG0343	queuine tRNA-ribosyltransferase activity
DLM_RS12140	COG1862	Preprotein translocase
DLM_RS12145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DLM_RS12150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DLM_RS12155	COG0586	Pfam SNARE associated Golgi protein
DLM_RS12165	COG1435	thymidine kinase activity
DLM_RS12170	COG2925	Exonuclease
DLM_RS12175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DLM_RS12180	COG0251	oxidation-reduction process
DLM_RS12190	COG1914	H( )-stimulated, divalent metal cation uptake system
DLM_RS12225	COG0482	sulfurtransferase activity
DLM_RS12240	COG0531	amino acid
DLM_RS12245	COG1166	arginine decarboxylase activity
DLM_RS12250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS12255	COG3842	ATPase activity
DLM_RS12260	COG2200	EAL domain
DLM_RS12270	COG1024	Enoyl-CoA hydratase
DLM_RS12270	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLM_RS12275	COG2988	succinylglutamate desuccinylase activity
DLM_RS12290	COG3951	Flagellar rod assembly protein muramidase FlgJ
DLM_RS12290	COG1705	Flagellar rod assembly protein muramidase FlgJ
DLM_RS12295	COG1706	bacterial-type flagellum-dependent cell motility
DLM_RS12300	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DLM_RS12315	COG1749	Flagellar hook protein flgE
DLM_RS12325	COG1558	bacterial-type flagellum-dependent cell motility
DLM_RS12330	COG1815	bacterial-type flagellum-dependent cell motility
DLM_RS12335	COG1765	OsmC-like protein
DLM_RS12340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DLM_RS12345	COG0488	(ABC) transporter
DLM_RS12355	COG0277	FAD linked oxidase domain protein
DLM_RS12360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DLM_RS12365	COG0159	tryptophan synthase activity
DLM_RS12370	COG0133	tryptophan synthase activity
DLM_RS12380	COG0101	tRNA pseudouridine synthase activity
DLM_RS12405	COG0473	3-isopropylmalate dehydrogenase activity
DLM_RS12410	COG2226	methyltransferase
DLM_RS12415	COG0066	3-isopropylmalate dehydratase activity
DLM_RS12420	COG5510	response to toxic substance
DLM_RS12425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DLM_RS12435	COG2814	Major facilitator Superfamily
DLM_RS12440	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DLM_RS12445	COG0179	Fumarylacetoacetate (FAA) hydrolase
DLM_RS12450	COG3243	poly(R)-hydroxyalkanoic acid synthase
DLM_RS12455	COG0183	Belongs to the thiolase family
DLM_RS12480	COG2267	carboxylic ester hydrolase activity
DLM_RS12485	COG1187	pseudouridine synthase activity
DLM_RS12490	COG0697	spore germination
DLM_RS12505	COG3008	intermembrane lipid transfer
DLM_RS12505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DLM_RS12510	COG2995	paraquat-inducible protein a
DLM_RS12535	COG0583	DNA-binding transcription factor activity
DLM_RS12540	COG1454	alcohol dehydrogenase
DLM_RS12560	COG0833	amino acid
DLM_RS12565	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DLM_RS12580	COG1335	isochorismatase
DLM_RS12585	COG2070	2-Nitropropane dioxygenase
DLM_RS12590	COG1522	sequence-specific DNA binding
DLM_RS12600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DLM_RS12610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_RS12615	COG0121	glutamine amidotransferase
DLM_RS12640	COG2003	Belongs to the UPF0758 family
DLM_RS12645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DLM_RS12650	COG0756	dUTP diphosphatase activity
DLM_RS12655	COG3706	GGDEF domain
DLM_RS12665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLM_RS12675	COG0625	glutathione transferase activity
DLM_RS12680	COG0583	DNA-binding transcription factor activity
DLM_RS12700	COG0525	valine-tRNA ligase activity
DLM_RS12705	COG0840	transmembrane signaling receptor activity
DLM_RS12750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DLM_RS12765	COG0300	oxidoreductase activity
DLM_RS12770	COG1722	exodeoxyribonuclease VII activity
DLM_RS12775	COG0142	geranyltranstransferase activity
DLM_RS12780	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DLM_RS12785	COG3174	membrane
DLM_RS12805	COG0628	permease
DLM_RS12810	COG0183	Belongs to the thiolase family
DLM_RS12815	COG0789	Transcriptional regulator
DLM_RS12820	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLM_RS12830	COG1960	acyl-CoA dehydrogenase activity
DLM_RS12835	COG1024	Enoyl-CoA hydratase
DLM_RS12840	COG1024	Enoyl-CoA hydratase
DLM_RS12855	COG1546	Belongs to the CinA family
DLM_RS12855	COG1058	Belongs to the CinA family
DLM_RS12880	COG0559	Belongs to the binding-protein-dependent transport system permease family
DLM_RS12885	COG3724	N-succinylarginine dihydrolase activity
DLM_RS12890	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS12905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DLM_RS12910	COG1185	polyribonucleotide nucleotidyltransferase activity
DLM_RS12915	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DLM_RS12920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DLM_RS12925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DLM_RS12930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DLM_RS12935	COG2251	uridine kinase activity
DLM_RS12935	COG0195	Participates in both transcription termination and antitermination
DLM_RS12940	COG0779	Required for maturation of 30S ribosomal subunits
DLM_RS12945	COG0318	PFAM AMP-dependent synthetase and ligase
DLM_RS12955	COG1393	Belongs to the ArsC family
DLM_RS12960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DLM_RS12985	COG2217	Heavy metal translocating P-type atpase
DLM_RS12990	COG2095	MarC family integral membrane protein
DLM_RS13000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_RS13005	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DLM_RS13015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DLM_RS13020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DLM_RS13025	COG2951	lytic endotransglycosylase activity
DLM_RS13030	COG1420	regulation of RNA biosynthetic process
DLM_RS13035	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DLM_RS13040	COG2137	regulation of response to DNA damage stimulus
DLM_RS13045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DLM_RS13085	COG2308	Evidence 4 Homologs of previously reported genes of
DLM_RS13125	COG0788	formyltetrahydrofolate deformylase activity
DLM_RS13130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DLM_RS13155	COG1802	Transcriptional regulator
DLM_RS13160	COG0583	DNA-binding transcription factor activity
DLM_RS13170	COG1741	Belongs to the pirin family
DLM_RS13190	COG4566	intracellular signal transduction
DLM_RS13205	COG3209	COG3209 Rhs family protein
DLM_RS13220	COG3209	COG3209 Rhs family protein
DLM_RS13225	COG3209	COG3209 Rhs family protein
DLM_RS13255	COG3209	COG3209 Rhs family protein
DLM_RS13265	COG3209	COG3209 Rhs family protein
DLM_RS13270	COG3209	COG3209 Rhs family protein
DLM_RS13285	COG3209	COG3209 Rhs family protein
DLM_RS13300	COG3209	COG3209 Rhs family protein
DLM_RS13335	COG3209	COG3209 Rhs family protein
DLM_RS13365	COG3209	COG3209 Rhs family protein
DLM_RS13375	COG3209	COG3209 Rhs family protein
DLM_RS13405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DLM_RS13410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS13425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DLM_RS13430	COG3842	ATPase activity
DLM_RS13435	COG4208	sulfate ABC transporter
DLM_RS13555	COG4386	tail sheath protein
DLM_RS13580	COG4397	Mu-like prophage major head subunit gpT
DLM_RS13605	COG5005	Phage virion morphogenesis
DLM_RS13615	COG4383	Mu-like prophage protein gp29
DLM_RS13750	COG2205	protein histidine kinase activity
DLM_RS13750	COG0784	Response regulator, receiver
DLM_RS13755	COG0745	RESPONSE REGULATOR receiver
DLM_RS13760	COG2205	protein histidine kinase activity
DLM_RS13760	COG0784	Response regulator, receiver
DLM_RS13760	COG5002	protein histidine kinase activity
DLM_RS13775	COG3186	Phenylalanine-4-hydroxylase
DLM_RS13785	COG2354	Protein conserved in bacteria
DLM_RS13805	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DLM_RS13810	COG2199	diguanylate cyclase activity
DLM_RS13810	COG2203	Gaf domain
DLM_RS13815	COG2181	nitrate reductase activity
DLM_RS13820	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DLM_RS13825	COG1140	nitrate reductase beta subunit
DLM_RS13830	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DLM_RS13835	COG3539	Fimbrial protein
DLM_RS13845	COG2223	nitrite transmembrane transporter activity
DLM_RS13855	COG3850	Histidine kinase
DLM_RS13860	COG2197	response regulator
DLM_RS13865	COG3706	GGDEF domain
DLM_RS13870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DLM_RS13875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DLM_RS13885	COG1120	ATPase activity
DLM_RS13910	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DLM_RS13915	COG4774	siderophore transport
DLM_RS13930	COG0535	radical SAM domain protein
DLM_RS13940	COG1522	sequence-specific DNA binding
DLM_RS13945	COG3391	amine dehydrogenase activity
DLM_RS13975	COG0714	Associated with various cellular activities
DLM_RS13985	COG1845	cytochrome c oxidase, subunit III
DLM_RS13990	COG3256	nitric oxide reductase
DLM_RS13995	COG2010	Cytochrome c
DLM_RS14000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DLM_RS14000	COG1648	precorrin-2 dehydrogenase activity
DLM_RS14065	COG0583	DNA-binding transcription factor activity
DLM_RS14080	COG2197	response regulator
DLM_RS14090	COG4948	Mandelate Racemase Muconate Lactonizing
DLM_RS14095	COG3842	ATPase activity
DLM_RS14105	COG1175	transmembrane transport
DLM_RS14110	COG0395	ABC-type sugar transport system, permease component
DLM_RS14125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DLM_RS14140	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DLM_RS14150	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DLM_RS14155	COG4689	acetoacetate decarboxylase
DLM_RS14160	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS14175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DLM_RS14180	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DLM_RS14180	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DLM_RS14190	COG0284	orotidine-5'-phosphate decarboxylase activity
DLM_RS14195	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DLM_RS14205	COG0776	regulation of translation
DLM_RS14215	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DLM_RS14220	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DLM_RS14230	COG3038	cytochrome b561
DLM_RS14240	COG0583	DNA-binding transcription factor activity
DLM_RS14245	COG1609	Transcriptional regulator
DLM_RS14250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DLM_RS14250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DLM_RS14255	COG1105	Belongs to the carbohydrate kinase PfkB family
DLM_RS14260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DLM_RS14260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DLM_RS14265	COG2211	Major facilitator Superfamily
DLM_RS14270	COG1472	Belongs to the glycosyl hydrolase 3 family
DLM_RS14275	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS14280	COG0023	Translation Initiation Factor
DLM_RS14290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS14400	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS14405	COG0287	Prephenate dehydrogenase
DLM_RS14415	COG2199	diguanylate cyclase activity
DLM_RS14415	COG2200	EAL domain
DLM_RS14420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DLM_RS14425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DLM_RS14430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DLM_RS14435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DLM_RS14440	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS14450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DLM_RS14455	COG0416	fatty acid biosynthetic process
DLM_RS14460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DLM_RS14465	COG1399	metal-binding, possibly nucleic acid-binding protein
DLM_RS14470	COG0424	maF-like protein
DLM_RS14480	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DLM_RS14490	COG1704	LemA family
DLM_RS14515	COG0747	negative chemotaxis
DLM_RS14525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DLM_RS14525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DLM_RS14530	COG0509	glycine decarboxylation via glycine cleavage system
DLM_RS14535	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DLM_RS14545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DLM_RS14550	COG2235	arginine
DLM_RS14555	COG0531	amino acid
DLM_RS14560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DLM_RS14570	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DLM_RS14575	COG2201	protein-glutamate methylesterase activity
DLM_RS14580	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DLM_RS14585	COG0840	transmembrane signaling receptor activity
DLM_RS14595	COG0643	Histidine kinase
DLM_RS14595	COG2198	Histidine kinase
DLM_RS14600	COG0745	RESPONSE REGULATOR receiver
DLM_RS14605	COG0840	transmembrane signaling receptor activity
DLM_RS14615	COG3852	Histidine kinase
DLM_RS14620	COG0835	chemotaxis
DLM_RS14620	COG0784	Response regulator, receiver
DLM_RS14625	COG0784	Response regulator, receiver
DLM_RS14625	COG0835	chemotaxis
DLM_RS14630	COG0745	RESPONSE REGULATOR receiver
DLM_RS14635	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DLM_RS14640	COG0784	Response regulator, receiver
DLM_RS14640	COG0643	Histidine kinase
DLM_RS14640	COG2198	Histidine kinase
DLM_RS14645	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DLM_RS14650	COG1214	PFAM Peptidase M22, glycoprotease
DLM_RS14655	COG0456	acetyltransferase
DLM_RS14660	COG1573	uracil-dna glycosylase
DLM_RS14665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DLM_RS14665	COG0519	Catalyzes the synthesis of GMP from XMP
DLM_RS14670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DLM_RS14675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DLM_RS14680	COG0504	CTP synthase activity
DLM_RS14685	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DLM_RS14690	COG0148	phosphopyruvate hydratase activity
DLM_RS14695	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DLM_RS14705	COG2914	Belongs to the UPF0125 (RnfH) family
DLM_RS14710	COG2867	negative regulation of translational initiation
DLM_RS14715	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DLM_RS14725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DLM_RS14725	COG0519	Catalyzes the synthesis of GMP from XMP
DLM_RS14750	COG0590	tRNA wobble adenosine to inosine editing
DLM_RS14770	COG1671	Belongs to the UPF0178 family
DLM_RS14790	COG4251	negative regulation of phosphorylation
DLM_RS14790	COG5001	Diguanylate cyclase
DLM_RS14790	COG2203	Gaf domain
DLM_RS14790	COG3706	GGDEF domain
DLM_RS14795	COG0583	DNA-binding transcription factor activity
DLM_RS14805	COG1335	isochorismatase
DLM_RS14835	COG0004	ammonium transporteR
DLM_RS14860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DLM_RS14870	COG1716	ATPase activity
DLM_RS14870	COG5001	Diguanylate cyclase
DLM_RS14885	COG0310	cobalt ion transport
DLM_RS14890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DLM_RS14895	COG1122	ATPase activity
DLM_RS14905	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS14915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS14925	COG2885	chlorophyll binding
DLM_RS14930	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DLM_RS14935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DLM_RS14950	COG4771	TonB-dependent receptor
DLM_RS14960	COG2205	protein histidine kinase activity
DLM_RS14975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DLM_RS14980	COG1454	alcohol dehydrogenase
DLM_RS15015	COG1309	transcriptional regulator
DLM_RS15020	COG0778	Nitroreductase
DLM_RS15025	COG1902	pentaerythritol trinitrate reductase activity
DLM_RS15035	COG1597	lipid kinase activity
DLM_RS15040	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DLM_RS15045	COG0720	synthase
DLM_RS15050	COG0602	queuosine metabolic process
DLM_RS15065	COG3220	belongs to the UPF0276 family
DLM_RS15080	COG0560	Phosphoserine phosphatase
DLM_RS15095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DLM_RS15100	COG0400	carboxylic ester hydrolase activity
DLM_RS15125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DLM_RS15140	COG0752	glycyl-tRNA synthetase alpha subunit
DLM_RS15145	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DLM_RS15150	COG1063	alcohol dehydrogenase
DLM_RS15160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLM_RS15165	COG4638	Rieske (2fe-2S)
DLM_RS15180	COG0473	3-isopropylmalate dehydrogenase activity
DLM_RS15185	COG0583	DNA-binding transcription factor activity
DLM_RS15210	COG0484	heat shock protein binding
DLM_RS15215	COG0443	Heat shock 70 kDa protein
DLM_RS15220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DLM_RS15230	COG2224	Isocitrate lyase
DLM_RS15240	COG0531	amino acid
DLM_RS15245	COG0583	DNA-binding transcription factor activity
DLM_RS15250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DLM_RS15265	COG1122	ATPase activity
DLM_RS15275	COG0625	glutathione transferase activity
DLM_RS15280	COG1742	UPF0060 membrane protein
DLM_RS15285	COG0583	DNA-binding transcription factor activity
DLM_RS15305	COG0326	Molecular chaperone. Has ATPase activity
DLM_RS15315	COG2233	PERMEase
DLM_RS15320	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DLM_RS15325	COG4266	Belongs to the allantoicase family
DLM_RS15335	COG3648	Uricase
DLM_RS15335	COG3195	allantoin biosynthetic process
DLM_RS15360	COG2084	Dehydrogenase
DLM_RS15365	COG3622	Belongs to the hyi family
DLM_RS15370	COG3960	tartronate-semialdehyde synthase activity
DLM_RS15380	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DLM_RS15385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DLM_RS15390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DLM_RS15395	COG0196	riboflavin kinase activity
DLM_RS15415	COG0175	sulfate reduction
DLM_RS15420	COG0583	DNA-binding transcription factor activity
DLM_RS15425	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS15430	COG0488	(ABC) transporter
DLM_RS15435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DLM_RS15440	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DLM_RS15450	COG2850	peptidyl-arginine hydroxylation
DLM_RS15455	COG1047	Peptidyl-prolyl cis-trans
DLM_RS15465	COG2239	Acts as a magnesium transporter
DLM_RS15470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DLM_RS15475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DLM_RS15485	COG0174	glutamine synthetase
DLM_RS15500	COG3852	Histidine kinase
DLM_RS15510	COG0583	DNA-binding transcription factor activity
DLM_RS15515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DLM_RS15525	COG1346	cytolysis
DLM_RS15535	COG3161	chorismate lyase activity
DLM_RS15540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DLM_RS15560	COG0494	nUDIX hydrolase
DLM_RS15565	COG0697	spore germination
DLM_RS15580	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DLM_RS15585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DLM_RS15590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DLM_RS15600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DLM_RS15600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DLM_RS15610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DLM_RS15615	COG3300	MHYT domain
DLM_RS15615	COG5001	Diguanylate cyclase
DLM_RS15620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DLM_RS15630	COG2233	PERMEase
DLM_RS15635	COG0456	acetyltransferase
DLM_RS15640	COG0456	acetyltransferase
DLM_RS15645	COG0247	lactate metabolic process
DLM_RS15645	COG0277	FAD linked oxidase domain protein
DLM_RS15650	COG1335	isochorismatase
DLM_RS15700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS15705	COG0359	binds to the 23S rRNA
DLM_RS15710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DLM_RS15720	COG0360	Binds together with S18 to 16S ribosomal RNA
DLM_RS15730	COG1937	Protein conserved in bacteria
DLM_RS15740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DLM_RS15750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DLM_RS15760	COG0183	Belongs to the thiolase family
DLM_RS15765	COG1024	Enoyl-CoA hydratase
DLM_RS15775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLM_RS15780	COG2151	metal-sulfur cluster biosynthetic enzyme
DLM_RS15785	COG3396	Phenylacetate-CoA oxygenase
DLM_RS15790	COG3460	Phenylacetate-CoA oxygenase
DLM_RS15795	COG3396	Phenylacetate-CoA oxygenase
DLM_RS15805	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLM_RS15810	COG1024	Enoyl-CoA hydratase
DLM_RS15815	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS15825	COG3162	membrane
DLM_RS15845	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS15845	COG1454	alcohol dehydrogenase
DLM_RS15850	COG0288	reversible hydration of carbon dioxide
DLM_RS15870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLM_RS15885	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DLM_RS15900	COG3045	CreA protein
DLM_RS15910	COG0321	lipoyl(octanoyl) transferase activity
DLM_RS15910	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DLM_RS15915	COG0084	hydrolase, TatD family'
DLM_RS15925	COG0470	DNA polymerase III
DLM_RS15930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DLM_RS15935	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DLM_RS15950	COG2186	Transcriptional regulator
DLM_RS15955	COG2807	transmembrane transport
DLM_RS15965	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DLM_RS15970	COG4181	ATPase activity
DLM_RS15990	COG0450	alkyl hydroperoxide reductase
DLM_RS15995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DLM_RS16010	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DLM_RS16020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DLM_RS16025	COG0268	Binds directly to 16S ribosomal RNA
DLM_RS16030	COG0728	peptidoglycan biosynthetic process
DLM_RS16040	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DLM_RS16040	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DLM_RS16045	COG1278	Cold shock
DLM_RS16050	COG0564	pseudouridine synthase activity
DLM_RS16055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DLM_RS16065	COG0494	nUDIX hydrolase
DLM_RS16070	COG0174	glutamine synthetase
DLM_RS16075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS16080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DLM_RS16120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLM_RS16135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DLM_RS16140	COG4608	Belongs to the ABC transporter superfamily
DLM_RS16145	COG0444	Belongs to the ABC transporter superfamily
DLM_RS16150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DLM_RS16155	COG0601	transmembrane transport
DLM_RS16160	COG0747	negative chemotaxis
DLM_RS16175	COG1104	cysteine desulfurase activity
DLM_RS16180	COG0822	iron-sulfur transferase activity
DLM_RS16190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DLM_RS16195	COG0443	Heat shock 70 kDa protein
DLM_RS16200	COG0633	Ferredoxin
DLM_RS16210	COG0625	glutathione transferase activity
DLM_RS16215	COG0572	uridine kinase
DLM_RS16225	COG2610	gluconate transmembrane transporter activity
DLM_RS16230	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DLM_RS16235	COG0251	oxidation-reduction process
DLM_RS16240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DLM_RS16270	COG3383	formate dehydrogenase (NAD+) activity
DLM_RS16340	COG4175	Glycine betaine
DLM_RS16345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLM_RS16360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DLM_RS16365	COG2181	nitrate reductase activity
DLM_RS16365	COG0247	lactate metabolic process
DLM_RS16370	COG1902	pentaerythritol trinitrate reductase activity
DLM_RS16370	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLM_RS16390	COG2113	Glycine betaine
DLM_RS16400	COG0477	Major facilitator Superfamily
DLM_RS16410	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLM_RS16410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DLM_RS16435	COG2337	Toxic component of a toxin-antitoxin (TA) module
DLM_RS16465	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS16485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLM_RS16485	COG1017	nitric oxide dioxygenase activity
DLM_RS16490	COG1959	2 iron, 2 sulfur cluster binding
DLM_RS16495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DLM_RS16500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DLM_RS16515	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DLM_RS16540	COG4095	Psort location CytoplasmicMembrane, score
DLM_RS16545	COG0584	glycerophosphoryl diester phosphodiesterase
DLM_RS16550	COG1294	oxidase, subunit
DLM_RS16555	COG1271	oxidase subunit
DLM_RS16565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DLM_RS16580	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DLM_RS16595	COG0538	isocitrate dehydrogenase activity
DLM_RS16605	COG0477	Major facilitator Superfamily
DLM_RS16610	COG1278	Cold shock
DLM_RS16615	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DLM_RS16620	COG0542	response to heat
DLM_RS16625	COG4974	Belongs to the 'phage' integrase family
DLM_RS16630	COG0335	large ribosomal subunit rRNA binding
DLM_RS16635	COG0336	Belongs to the RNA methyltransferase TrmD family
DLM_RS16640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DLM_RS16645	COG0228	four-way junction DNA binding
DLM_RS16650	COG1042	CoA-binding domain protein
DLM_RS16650	COG0045	succinate-CoA ligase (ADP-forming) activity
DLM_RS16650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DLM_RS16655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DLM_RS16660	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DLM_RS16665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DLM_RS16670	COG4942	peptidase
DLM_RS16670	COG1388	LysM domain
DLM_RS16675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DLM_RS16690	COG0714	Associated with various cellular activities
DLM_RS16695	COG0123	including yeast histone deacetylase and acetoin utilization protein
DLM_RS16700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DLM_RS16720	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DLM_RS16725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS16730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DLM_RS16735	COG0316	Belongs to the HesB IscA family
DLM_RS16740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DLM_RS16750	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DLM_RS16755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DLM_RS16760	COG0813	purine-nucleoside phosphorylase activity
DLM_RS16765	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DLM_RS16770	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DLM_RS16775	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DLM_RS16785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DLM_RS16790	COG1194	a g-specific adenine glycosylase
DLM_RS16805	COG2095	MarC family integral membrane protein
DLM_RS16815	COG1301	dicarboxylic acid transport
DLM_RS16820	COG0583	DNA-binding transcription factor activity
DLM_RS16840	COG0561	phosphatase activity
DLM_RS16855	COG0625	glutathione transferase activity
DLM_RS16865	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DLM_RS16880	COG1522	sequence-specific DNA binding
DLM_RS16885	COG1879	ABC-type sugar transport system periplasmic component
DLM_RS16890	COG5001	Diguanylate cyclase
DLM_RS16890	COG2203	Gaf domain
DLM_RS16890	COG3706	GGDEF domain
DLM_RS16890	COG4251	negative regulation of phosphorylation
DLM_RS16895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DLM_RS16900	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DLM_RS16910	COG2969	positive regulation of protein catabolic process
DLM_RS16915	COG0625	glutathione transferase activity
DLM_RS16920	COG2857	Cytochrome c1
DLM_RS16925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DLM_RS16930	COG0723	plastoquinol--plastocyanin reductase activity
DLM_RS16940	COG0459	protein refolding
DLM_RS16950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DLM_RS16965	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DLM_RS16975	COG1086	Polysaccharide biosynthesis protein
DLM_RS16980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DLM_RS16990	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DLM_RS16995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DLM_RS17000	COG3980	spore coat polysaccharide biosynthesis protein
DLM_RS17005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DLM_RS17010	COG2089	acid synthase
DLM_RS17020	COG0110	maltose O-acetyltransferase activity
DLM_RS17045	COG0493	'glutamate synthase
DLM_RS17055	COG0067	glutamate synthase
DLM_RS17055	COG0069	glutamate synthase activity
DLM_RS17055	COG0070	glutamate synthase
DLM_RS17090	COG0626	cystathionine gamma-synthase activity
DLM_RS17095	COG1022	Amp-dependent synthetase and ligase
DLM_RS17100	COG0765	amino acid transport
DLM_RS17105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS17125	COG1401	restriction endodeoxyribonuclease activity
DLM_RS17145	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DLM_RS17155	COG0012	GTP binding
DLM_RS17160	COG0193	aminoacyl-tRNA hydrolase activity
DLM_RS17165	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DLM_RS17170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DLM_RS17180	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DLM_RS17185	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DLM_RS17195	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DLM_RS17205	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DLM_RS17215	COG3245	cytochrome
DLM_RS17230	COG2193	ferroxidase activity
DLM_RS17235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS17235	COG2205	protein histidine kinase activity
DLM_RS17255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DLM_RS17270	COG1074	ATP-dependent DNA helicase activity
DLM_RS17275	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DLM_RS17285	COG0826	peptidase U32
DLM_RS17290	COG0826	peptidase U32
DLM_RS17295	COG3154	lipid carrier protein
DLM_RS17300	COG0583	DNA-binding transcription factor activity
DLM_RS17305	COG2197	response regulator
DLM_RS17310	COG1012	belongs to the aldehyde dehydrogenase family
DLM_RS17320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DLM_RS17350	COG0318	PFAM AMP-dependent synthetase and ligase
DLM_RS17370	COG0642	Histidine kinase
DLM_RS17375	COG0745	RESPONSE REGULATOR receiver
DLM_RS17395	COG0438	transferase activity, transferring glycosyl groups
DLM_RS17400	COG0473	3-isopropylmalate dehydrogenase activity
DLM_RS17415	COG2226	methyltransferase
DLM_RS17420	COG0708	Exodeoxyribonuclease III
DLM_RS17425	COG2194	sulfuric ester hydrolase activity
DLM_RS17430	COG0339	signal peptide processing
DLM_RS17435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DLM_RS17450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DLM_RS17460	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DLM_RS17505	COG0840	transmembrane signaling receptor activity
DLM_RS17515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DLM_RS17530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DLM_RS17540	COG1196	nuclear chromosome segregation
DLM_RS17565	COG0583	DNA-binding transcription factor activity
DLM_RS17590	COG4598	ABC transporter
DLM_RS17595	COG4160	amino acid transport
DLM_RS17610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DLM_RS17615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DLM_RS17620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DLM_RS17625	COG0142	geranyltranstransferase activity
DLM_RS17635	COG0582	viral genome integration into host DNA
DLM_RS17640	COG4735	regulation of single-species biofilm formation
DLM_RS17680	COG3596	GTP binding
DLM_RS17725	COG2755	lipolytic protein G-D-S-L family
DLM_RS17725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DLM_RS17730	COG1283	sodium-dependent phosphate transmembrane transporter activity
DLM_RS17735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DLM_RS17750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_RS17755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_RS17790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DLM_RS17795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DLM_RS17805	COG1132	(ABC) transporter
DLM_RS17825	COG0859	PFAM glycosyl transferase family 9
DLM_RS17835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DLM_RS17840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DLM_RS17850	COG1648	precorrin-2 dehydrogenase activity
DLM_RS17850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DLM_RS17865	COG1295	ribonuclease BN
DLM_RS17865	COG1959	2 iron, 2 sulfur cluster binding
DLM_RS17880	COG2207	Transcriptional regulator
DLM_RS17885	COG2223	nitrite transmembrane transporter activity
DLM_RS17895	COG2814	Major facilitator Superfamily
DLM_RS17900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DLM_RS17900	COG2813	Specifically methylates the guanine in position
DLM_RS17905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DLM_RS17915	COG1242	4 iron, 4 sulfur cluster binding
DLM_RS17920	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DLM_RS17935	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLM_RS17940	COG1024	Enoyl-CoA hydratase
DLM_RS17945	COG0477	Major facilitator Superfamily
DLM_RS17950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DLM_RS17955	COG1960	acyl-CoA dehydrogenase activity
DLM_RS17960	COG0583	DNA-binding transcription factor activity
DLM_RS17995	COG1393	Belongs to the ArsC family
DLM_RS18000	COG1846	Transcriptional regulator
DLM_RS18010	COG1566	PFAM secretion protein HlyD family protein
DLM_RS18015	COG2814	Major facilitator Superfamily
DLM_RS18035	COG1129	ABC transporter
DLM_RS18050	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS18055	COG0800	Aldolase
DLM_RS18060	COG4948	Mandelate Racemase Muconate Lactonizing
DLM_RS18065	COG2017	converts alpha-aldose to the beta-anomer
DLM_RS18070	COG1063	alcohol dehydrogenase
DLM_RS18075	COG1172	Belongs to the binding-protein-dependent transport system permease family
DLM_RS18080	COG1129	ABC transporter
DLM_RS18085	COG1879	ABC-type sugar transport system periplasmic component
DLM_RS18140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DLM_RS18140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DLM_RS18145	COG1611	Belongs to the LOG family
DLM_RS18155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DLM_RS18160	COG0583	DNA-binding transcription factor activity
DLM_RS18165	COG2855	membrane
DLM_RS18170	COG2879	small protein
DLM_RS18175	COG1966	Carbon starvation protein
DLM_RS18180	COG0745	RESPONSE REGULATOR receiver
DLM_RS18185	COG2205	protein histidine kinase activity
DLM_RS18195	COG0408	coproporphyrinogen oxidase activity
DLM_RS18200	COG3706	GGDEF domain
DLM_RS18205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DLM_RS18210	COG0583	DNA-binding transcription factor activity
DLM_RS18230	COG0840	transmembrane signaling receptor activity
DLM_RS18240	COG4566	intracellular signal transduction
DLM_RS18250	COG0477	Major facilitator Superfamily
DLM_RS18260	COG0477	Major facilitator Superfamily
DLM_RS18265	COG0667	Aldo Keto reductase
DLM_RS18270	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
DLM_RS18370	COG1595	DNA-templated transcription, initiation
DLM_RS18380	COG4771	TonB-dependent receptor
DLM_RS18385	COG0612	Peptidase, M16
DLM_RS18390	COG4178	(ABC) transporter
DLM_RS18395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DLM_RS18400	COG1349	DNA-binding transcription factor activity
DLM_RS18405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DLM_RS18410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DLM_RS18415	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DLM_RS18420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DLM_RS18425	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DLM_RS18430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DLM_RS18435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DLM_RS18445	COG0356	it plays a direct role in the translocation of protons across the membrane
DLM_RS18460	COG1192	Involved in chromosome partitioning
DLM_RS18465	COG0357	Ribosomal RNA small subunit methyltransferase G
DLM_RS18470	COG0445	tRNA wobble uridine modification
DLM_RS18480	COG1720	tRNA m6t6A37 methyltransferase activity
DLM_RS18490	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DLM_RS18495	COG2823	Periplasmic or secreted lipoprotein
DLM_RS18500	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DLM_RS18505	COG0792	nuclease activity
DLM_RS18530	COG0515	serine threonine protein kinase
DLM_RS18535	COG0515	serine threonine protein kinase
DLM_RS18535	COG2815	serine threonine protein kinase
DLM_RS18550	COG0084	hydrolase, TatD family'
DLM_RS18560	COG1538	Outer membrane efflux protein
DLM_RS18585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_RS18590	COG2274	protein secretion by the type I secretion system
DLM_RS18605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DLM_RS18610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DLM_RS18620	COG0140	phosphoribosyl-ATP diphosphatase activity
DLM_RS18625	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DLM_RS18630	COG0107	imidazoleglycerol-phosphate synthase activity
DLM_RS18635	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DLM_RS18640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DLM_RS18645	COG0131	Imidazoleglycerol-phosphate dehydratase
DLM_RS18650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DLM_RS18655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DLM_RS18660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DLM_RS18665	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DLM_RS18670	COG1999	signal sequence binding
DLM_RS18675	COG0109	protoheme IX farnesyltransferase activity
DLM_RS18680	COG1612	heme a metabolic process
DLM_RS18715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DLM_RS18730	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DLM_RS18735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DLM_RS18740	COG1183	phosphatidylcholine synthase activity
DLM_RS18745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DLM_RS18750	COG0440	acetolactate synthase activity
DLM_RS18755	COG0028	Belongs to the TPP enzyme family
DLM_RS18780	COG1846	Transcriptional regulator
DLM_RS18785	COG1914	H( )-stimulated, divalent metal cation uptake system
DLM_RS18790	COG0741	lytic transglycosylase activity
DLM_RS18795	COG0442	prolyl-tRNA aminoacylation
DLM_RS18800	COG3158	transport of potassium into the cell
DLM_RS18810	COG3945	hemerythrin HHE cation binding domain
DLM_RS18815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DLM_RS18830	COG0745	RESPONSE REGULATOR receiver
DLM_RS18835	COG1522	sequence-specific DNA binding
DLM_RS18840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DLM_RS18845	COG2190	(PTS) system
DLM_RS18845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DLM_RS18845	COG1263	PTS System
DLM_RS18850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DLM_RS18855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DLM_RS18860	COG2188	Transcriptional regulator
DLM_RS18865	COG0697	spore germination
DLM_RS18875	COG0009	L-threonylcarbamoyladenylate synthase
DLM_RS18895	COG0138	bifunctional purine biosynthesis protein purh
DLM_RS18905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DLM_RS18920	COG0477	Major facilitator Superfamily
DLM_RS18930	COG1473	amidohydrolase
DLM_RS18945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DLM_RS18950	COG0508	dehydrogenase complex catalyzes the overall conversion of
DLM_RS18960	COG4783	chaperone-mediated protein folding
DLM_RS18980	COG0640	Transcriptional regulator
DLM_RS19000	COG0288	reversible hydration of carbon dioxide
DLM_RS19005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DLM_RS19010	COG0799	negative regulation of ribosome biogenesis
DLM_RS19015	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DLM_RS19045	COG1196	nuclear chromosome segregation
DLM_RS19045	COG0741	lytic transglycosylase activity
DLM_RS19045	COG0739	heme binding
DLM_RS19055	COG1466	dna polymerase III delta subunit
DLM_RS19060	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
DLM_RS19065	COG0495	leucyl-tRNA aminoacylation
DLM_RS19080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DLM_RS19100	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DLM_RS19110	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DLM_RS19145	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DLM_RS19155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DLM_RS19215	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DLM_RS19220	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DLM_RS19240	COG4774	siderophore transport
DLM_RS19245	COG3128	pkhd-type hydroxylase
DLM_RS19250	COG0840	transmembrane signaling receptor activity
DLM_RS19285	COG5001	Diguanylate cyclase
DLM_RS19285	COG3447	MASE1 domain protein
DLM_RS19285	COG5002	protein histidine kinase activity
DLM_RS19300	COG0513	Belongs to the DEAD box helicase family
DLM_RS19320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DLM_RS19330	COG1522	sequence-specific DNA binding
DLM_RS19340	COG1451	nucleotide metabolic process
DLM_RS19345	COG0657	acetylesterase activity
DLM_RS19360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DLM_RS19365	COG1132	(ABC) transporter
DLM_RS19370	COG2841	Protein conserved in bacteria
DLM_RS19390	COG3150	esterase
DLM_RS19395	COG5002	protein histidine kinase activity
DLM_RS19395	COG0784	Response regulator, receiver
DLM_RS19445	COG0069	glutamate synthase activity
DLM_RS19495	COG1177	transmembrane transport
DLM_RS19500	COG1176	ABC-type spermidine putrescine transport system, permease component I
DLM_RS19505	COG3842	ATPase activity
DLM_RS19535	COG0697	spore germination
DLM_RS19540	COG1522	sequence-specific DNA binding
DLM_RS19550	COG0006	proline dipeptidase activity
DLM_RS19565	COG3135	benzoate transporter
DLM_RS19570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_RS19575	COG0579	oxidoreductase
DLM_RS19615	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DLM_RS19620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DLM_RS19680	COG1573	uracil-dna glycosylase
DLM_RS19690	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DLM_RS19695	COG2986	histidine ammonia-lyase
DLM_RS19700	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DLM_RS19705	COG0010	Belongs to the arginase family
DLM_RS19710	COG1228	amidohydrolase
DLM_RS19715	COG1968	undecaprenyl-diphosphatase activity
DLM_RS19720	COG2188	Transcriptional regulator
DLM_RS19725	COG0676	glucose-6-phosphate 1-epimerase activity
DLM_RS19735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DLM_RS19745	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DLM_RS19760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DLM_RS19800	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
DLM_RS19805	COG0540	Belongs to the ATCase OTCase family
DLM_RS19810	COG1280	lysine exporter protein (LysE YggA)
DLM_RS19830	COG0668	transmembrane transport
DLM_RS19835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DLM_RS19845	COG0625	glutathione transferase activity
DLM_RS19850	COG4628	conserved protein (DUF2132)
DLM_RS19880	COG0826	peptidase U32
DLM_RS19890	COG3214	Protein conserved in bacteria
DLM_RS19905	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DLM_RS19910	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DLM_RS19920	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DLM_RS19925	COG1253	flavin adenine dinucleotide binding
DLM_RS19930	COG4651	solute:proton antiporter activity
DLM_RS19930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DLM_RS19955	COG0859	PFAM glycosyl transferase family 9
DLM_RS19960	COG1519	Transferase
DLM_RS19970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_RS19975	COG1131	(ABC) transporter
DLM_RS19980	COG0842	Transport permease protein
DLM_RS19985	COG0842	Transport permease protein
DLM_RS20000	COG0583	DNA-binding transcription factor activity
DLM_RS20005	COG0352	thiamine-phosphate diphosphorylase activity
DLM_RS20010	COG0351	phosphomethylpyrimidine kinase
DLM_RS20015	COG1773	rubredoxin
DLM_RS20020	COG4783	chaperone-mediated protein folding
DLM_RS20025	COG1981	membrane
DLM_RS20030	COG2954	triphosphatase activity
DLM_RS20035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DLM_RS20065	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DLM_RS20085	COG2378	regulation of single-species biofilm formation
DLM_RS20105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DLM_RS20115	COG1238	metal cluster binding
DLM_RS20120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DLM_RS20125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS20130	COG0765	amino acid transport
DLM_RS20135	COG0765	amino acid transport
DLM_RS20140	COG1126	abc transporter atp-binding protein
DLM_RS20145	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DLM_RS20175	COG0762	integral membrane protein
DLM_RS20180	COG4654	Cytochrome c, class I
DLM_RS20190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DLM_RS20200	COG0583	DNA-binding transcription factor activity
DLM_RS20210	COG0314	molybdopterin synthase activity
DLM_RS20215	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DLM_RS20230	COG1280	lysine exporter protein (LysE YggA)
DLM_RS20235	COG0126	phosphoglycerate kinase activity
DLM_RS20240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DLM_RS20245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DLM_RS20255	COG2153	protein acetylation
DLM_RS20310	COG2201	protein-glutamate methylesterase activity
DLM_RS20315	COG2205	protein histidine kinase activity
DLM_RS20315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_RS20320	COG0583	DNA-binding transcription factor activity
DLM_RS20325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DLM_RS20330	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DLM_RS20335	COG0259	pyridoxamine-phosphate oxidase activity
DLM_RS20345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DLM_RS20375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DLM_RS20380	COG0583	DNA-binding transcription factor activity
DLM_RS20405	COG1132	(ABC) transporter
DLM_RS20410	COG3048	D-serine ammonia-lyase activity
DLM_RS20415	COG0583	DNA-binding transcription factor activity
DLM_RS20425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_RS20435	COG4251	negative regulation of phosphorylation
DLM_RS20435	COG3706	GGDEF domain
DLM_RS20435	COG2203	Gaf domain
DLM_RS20435	COG5001	Diguanylate cyclase
DLM_RS20445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DLM_RS20450	COG0235	Class ii aldolase
DLM_RS20470	COG1858	cytochrome C peroxidase
DLM_RS20490	COG2066	Belongs to the glutaminase family
DLM_RS20525	COG0864	Transcriptional regulator
DLM_RS20555	COG3012	SEC-C Motif Domain Protein
DLM_RS20575	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DLM_RS20580	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DLM_RS20585	COG0594	ribonuclease P activity
DLM_RS20590	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DLM_RS20595	COG0706	membrane insertase activity
DLM_RS20600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DLM_RS20605	COG0582	viral genome integration into host DNA
DLM_RS20680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DLM_RS20700	COG2959	enzyme of heme biosynthesis
DLM_RS20710	COG0181	hydroxymethylbilane synthase activity
DLM_RS20715	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DLM_RS20730	COG3275	phosphorelay sensor kinase activity
DLM_RS20745	COG0165	Argininosuccinate lyase
DLM_RS20750	COG2200	EAL domain
DLM_RS20770	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
DLM_RS20780	COG4989	oxidoreductase activity
DLM_RS20785	COG3842	ATPase activity
DLM_RS20790	COG0395	ABC-type sugar transport system, permease component
DLM_RS20795	COG1175	transmembrane transport
DLM_RS20815	COG0800	Aldolase
DLM_RS20820	COG0129	dihydroxy-acid dehydratase activity
DLM_RS20825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DLM_RS20835	COG0837	glucose binding
DLM_RS20845	COG0166	Belongs to the GPI family
DLM_RS20860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DLM_RS20870	COG2827	Endonuclease containing a URI domain
DLM_RS20875	COG1253	flavin adenine dinucleotide binding
DLM_RS20880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DLM_RS20885	COG1333	cytochrome c biogenesis protein
DLM_RS20895	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DLM_RS20905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DLM_RS20910	COG1040	competence protein
DLM_RS20915	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DLM_RS20920	COG0156	8-amino-7-oxononanoate synthase activity
DLM_RS20925	COG3300	MHYT domain
DLM_RS20925	COG5001	Diguanylate cyclase
DLM_RS20930	COG2267	carboxylic ester hydrolase activity
DLM_RS20935	COG2226	methyltransferase
DLM_RS20940	COG1752	Esterase of the alpha-beta hydrolase superfamily
DLM_RS20945	COG0625	glutathione transferase activity
DLM_RS20950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DLM_RS20960	COG2847	Copper chaperone PCu(A)C
DLM_RS20975	COG3791	Glutathione-dependent formaldehyde-activating
DLM_RS20990	COG0772	Belongs to the SEDS family
DLM_RS20995	COG0768	penicillin binding
DLM_RS21000	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DLM_RS21005	COG1792	Involved in formation and maintenance of cell shape
DLM_RS21010	COG1077	Cell shape determining protein MreB Mrl
DLM_RS21020	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DLM_RS21025	COG0154	amidase activity
DLM_RS21030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DLM_RS21035	COG2001	Belongs to the MraZ family
DLM_RS21040	COG0275	rRNA processing
DLM_RS21045	COG3116	cell division
DLM_RS21055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DLM_RS21060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DLM_RS21065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DLM_RS21070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DLM_RS21075	COG0772	Belongs to the SEDS family
DLM_RS21080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DLM_RS21085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DLM_RS21090	COG1181	Belongs to the D-alanine--D-alanine ligase family
DLM_RS21095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DLM_RS21110	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DLM_RS21120	COG0315	cyclic pyranopterin monophosphate synthase activity
DLM_RS21150	COG0418	dihydroorotase activity
DLM_RS21155	COG4166	transmembrane transport
DLM_RS21160	COG0601	transmembrane transport
DLM_RS21165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DLM_RS21175	COG4608	Belongs to the ABC transporter superfamily
DLM_RS21180	COG0501	Belongs to the peptidase M48B family
DLM_RS21185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DLM_RS21205	COG1505	serine-type exopeptidase activity
DLM_RS21225	COG3132	Protein of unknown function, DUF480
DLM_RS21235	COG0589	response to stress
DLM_RS21245	COG0405	Gamma-glutamyltransferase
DLM_RS21250	COG0174	glutamine synthetase
DLM_RS21255	COG0840	transmembrane signaling receptor activity
DLM_RS21275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DLM_RS21295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DLM_RS21300	COG0840	transmembrane signaling receptor activity
DLM_RS21320	COG4208	sulfate ABC transporter
DLM_RS21325	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DLM_RS21340	COG1116	anion transmembrane transporter activity
DLM_RS21350	COG0653	protein targeting
DLM_RS21355	COG0424	maF-like protein
DLM_RS21360	COG1530	ribonuclease E activity
DLM_RS21365	COG1045	serine acetyltransferase
DLM_RS21385	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DLM_RS21400	COG0210	DNA helicase
DLM_RS21445	COG0823	Involved in the tonB-independent uptake of proteins
DLM_RS21455	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DLM_RS21470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DLM_RS21475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DLM_RS21480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DLM_RS21485	COG2267	carboxylic ester hydrolase activity
DLM_RS21505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DLM_RS21545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DLM_RS21545	COG3433	isochorismatase activity
DLM_RS21545	COG2226	methyltransferase
DLM_RS21565	COG1902	pentaerythritol trinitrate reductase activity
DLM_RS21565	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLM_RS21570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLM_RS21575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DLM_RS21590	COG0189	ligase activity
DLM_RS21620	COG2922	Belongs to the Smg family
DLM_RS21625	COG0758	DNA mediated transformation
DLM_RS21635	COG0242	peptide deformylase activity
DLM_RS21640	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DLM_RS21645	COG0501	Belongs to the peptidase M48B family
DLM_RS21660	COG5000	phosphorelay sensor kinase activity
DLM_RS21665	COG2204	response regulator
DLM_RS21670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DLM_RS21675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLM_RS21680	COG0824	Thioesterase
DLM_RS21695	COG0783	Belongs to the Dps family
DLM_RS21700	COG1872	DUF167
DLM_RS21710	COG1324	tolerance protein
DLM_RS21755	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DLM_RS21760	COG0708	Exodeoxyribonuclease III
DLM_RS21785	COG1253	flavin adenine dinucleotide binding
DLM_RS21805	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DLM_RS21810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLM_RS21815	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DLM_RS21830	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DLM_RS21840	COG0632	four-way junction helicase activity
DLM_RS21845	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DLM_RS21850	COG2255	four-way junction helicase activity
DLM_RS21855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DLM_RS21855	COG0519	Catalyzes the synthesis of GMP from XMP
DLM_RS21870	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DLM_RS21885	COG4969	Belongs to the N-Me-Phe pilin family
DLM_RS21900	COG3307	-O-antigen
DLM_RS21905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DLM_RS21915	COG2884	Cell division ATP-binding protein ftsE
DLM_RS21925	COG0612	Peptidase, M16
DLM_RS21930	COG0612	Peptidase, M16
DLM_RS21935	COG0742	ribosomal rna small subunit methyltransferase
DLM_RS21940	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DLM_RS21960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DLM_RS21980	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DLM_RS21985	COG0081	regulation of translation
DLM_RS21995	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DLM_RS22000	COG0222	ribosome binding
DLM_RS22005	COG0085	RNA polymerase activity
DLM_RS22010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DLM_RS22015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DLM_RS22020	COG0049	tRNA binding
DLM_RS22025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DLM_RS22030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DLM_RS22035	COG0051	transcription antitermination factor activity, RNA binding
DLM_RS22040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DLM_RS22045	COG0088	Forms part of the polypeptide exit tunnel
DLM_RS22050	COG0089	rRNA binding
DLM_RS22055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DLM_RS22060	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DLM_RS22065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DLM_RS22070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DLM_RS22075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DLM_RS22080	COG0255	Belongs to the universal ribosomal protein uL29 family
DLM_RS22085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DLM_RS22090	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DLM_RS22095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DLM_RS22100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DLM_RS22105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DLM_RS22110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DLM_RS22115	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DLM_RS22120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DLM_RS22125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DLM_RS22130	COG1841	ribosomal large subunit assembly
DLM_RS22135	COG0200	Binds to the 23S rRNA
DLM_RS22140	COG0201	protein transport
DLM_RS22145	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DLM_RS22150	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DLM_RS22155	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DLM_RS22160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DLM_RS22165	COG0202	RNA polymerase activity
DLM_RS22170	COG0203	ribosomal protein L17
DLM_RS22175	COG3217	Mosc domain protein beta barrel domain protein
DLM_RS22175	COG0633	Ferredoxin
DLM_RS22180	COG0840	transmembrane signaling receptor activity
DLM_RS22185	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DLM_RS22190	COG4535	Mg2 and Co2 transporter CorC
DLM_RS22195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DLM_RS22200	COG1702	phosphate starvation-inducible protein PhoH
DLM_RS22215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DLM_RS22225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DLM_RS22230	COG1869	D-ribose catabolic process
DLM_RS22235	COG1129	ABC transporter
DLM_RS22240	COG1172	Belongs to the binding-protein-dependent transport system permease family
DLM_RS22245	COG1879	ABC-type sugar transport system periplasmic component
DLM_RS22265	COG1187	pseudouridine synthase activity
DLM_RS22270	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DLM_RS22290	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_RS22295	COG0037	tRNA processing
DLM_RS22300	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DLM_RS22345	COG0297	glycogen (starch) synthase activity
DLM_RS22370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DLM_RS22375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DLM_RS22390	COG0583	DNA-binding transcription factor activity
DLM_RS22395	COG0406	alpha-ribazole phosphatase activity
DLM_RS22400	COG1027	Aspartate ammonia-lyase
DLM_RS22420	COG3171	Protein conserved in bacteria
DLM_RS22425	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DLM_RS22430	COG3047	cAMP biosynthetic process
DLM_RS22470	COG1131	(ABC) transporter
DLM_RS22475	COG0842	Transport permease protein
DLM_RS22485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DLM_RS22490	COG0840	transmembrane signaling receptor activity
DLM_RS22495	COG2853	Lipoprotein
DLM_RS22510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DLM_RS22515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DLM_RS22520	COG1127	ABC transporter
DLM_RS22525	COG2171	N-acyltransferase activity
DLM_RS22545	COG2900	Belongs to the SlyX family
DLM_RS22560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DLM_RS22575	COG2205	protein histidine kinase activity
DLM_RS22580	COG1192	Involved in chromosome partitioning
DLM_RS22590	COG0514	ATP-dependent DNA helicase (RecQ)
DLM_RS22595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DLM_RS22630	COG1683	Conserved Protein
DLM_RS22660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DLM_RS22670	COG1538	Outer membrane efflux protein
DLM_RS22675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_RS22690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DLM_RS22700	COG1414	Transcriptional regulator
DLM_RS22710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DLM_RS22730	COG3530	Putative quorum-sensing-regulated virulence factor
DLM_RS22735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DLM_RS22750	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DLM_RS22755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DLM_RS22765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DLM_RS22775	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DLM_RS22780	COG1846	Transcriptional regulator
DLM_RS22785	COG3038	cytochrome b561
DLM_RS22790	COG2353	YceI-like domain
DLM_RS22800	COG2223	nitrite transmembrane transporter activity
DLM_RS22810	COG1678	Uncharacterized ACR, COG1678
DLM_RS22815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DLM_RS22840	COG1215	transferase activity, transferring glycosyl groups
DLM_RS22845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DLM_RS22855	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DLM_RS22865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate