locus-tag	class	description
FSB73_RS00020	COG4206	TonB-dependent receptor
FSB73_RS00020	COG1629	transport
FSB73_RS00050	COG0702	epimerase
FSB73_RS00060	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FSB73_RS00115	COG3250	beta-galactosidase activity
FSB73_RS00150	COG1809	phosphosulfolactate synthase activity
FSB73_RS00175	COG0445	tRNA wobble uridine modification
FSB73_RS00200	COG3119	arylsulfatase activity
FSB73_RS00210	COG0702	epimerase
FSB73_RS00215	COG1629	transport
FSB73_RS00235	COG0745	RESPONSE REGULATOR receiver
FSB73_RS00235	COG3292	Two component regulator propeller
FSB73_RS00235	COG2205	protein histidine kinase activity
FSB73_RS00245	COG2205	protein histidine kinase activity
FSB73_RS00245	COG3292	Two component regulator propeller
FSB73_RS00245	COG0745	RESPONSE REGULATOR receiver
FSB73_RS00275	COG0702	epimerase
FSB73_RS00280	COG4771	TonB-dependent receptor
FSB73_RS00325	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FSB73_RS00340	COG4771	TonB-dependent receptor
FSB73_RS00345	COG2205	protein histidine kinase activity
FSB73_RS00345	COG0745	RESPONSE REGULATOR receiver
FSB73_RS00345	COG3292	Two component regulator propeller
FSB73_RS00355	COG0745	RESPONSE REGULATOR receiver
FSB73_RS00355	COG2205	protein histidine kinase activity
FSB73_RS00355	COG3292	Two component regulator propeller
FSB73_RS00370	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FSB73_RS00395	COG3940	Belongs to the glycosyl hydrolase 43 family
FSB73_RS00420	COG3292	Two component regulator propeller
FSB73_RS00420	COG0745	RESPONSE REGULATOR receiver
FSB73_RS00420	COG2205	protein histidine kinase activity
FSB73_RS00425	COG3661	Belongs to the glycosyl hydrolase 67 family
FSB73_RS00435	COG1629	transport
FSB73_RS00485	COG1629	transport
FSB73_RS00495	COG0702	epimerase
FSB73_RS00515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS00545	COG4771	TonB-dependent receptor
FSB73_RS00590	COG5002	protein histidine kinase activity
FSB73_RS00595	COG0745	RESPONSE REGULATOR receiver
FSB73_RS00605	COG1012	belongs to the aldehyde dehydrogenase family
FSB73_RS00610	COG1285	pathogenesis
FSB73_RS00695	COG1629	transport
FSB73_RS00700	COG1629	transport
FSB73_RS00735	COG3291	Pkd domain containing protein
FSB73_RS00750	COG0076	glutamate decarboxylase activity
FSB73_RS00760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSB73_RS00780	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FSB73_RS00810	COG0584	glycerophosphoryl diester phosphodiesterase
FSB73_RS00830	COG1629	transport
FSB73_RS00835	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FSB73_RS00840	COG1349	DNA-binding transcription factor activity
FSB73_RS00850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FSB73_RS00855	COG3119	arylsulfatase activity
FSB73_RS00875	COG2610	gluconate transmembrane transporter activity
FSB73_RS00890	COG1846	Transcriptional regulator
FSB73_RS00895	COG2353	YceI-like domain
FSB73_RS00910	COG2814	Major facilitator Superfamily
FSB73_RS00915	COG0477	Major facilitator Superfamily
FSB73_RS00930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSB73_RS00935	COG1490	D-aminoacyl-tRNA deacylase activity
FSB73_RS00940	COG1694	Mazg nucleotide pyrophosphohydrolase
FSB73_RS00945	COG1295	ribonuclease BN
FSB73_RS00945	COG1959	2 iron, 2 sulfur cluster binding
FSB73_RS00950	COG1702	phosphate starvation-inducible protein PhoH
FSB73_RS00960	COG3340	Belongs to the peptidase S51 family
FSB73_RS00980	COG1127	ABC transporter
FSB73_RS00985	COG4221	oxidoreductase activity
FSB73_RS01000	COG0297	glycogen (starch) synthase activity
FSB73_RS01005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FSB73_RS01020	COG0443	Heat shock 70 kDa protein
FSB73_RS01025	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FSB73_RS01030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSB73_RS01035	COG0138	bifunctional purine biosynthesis protein purh
FSB73_RS01040	COG0049	tRNA binding
FSB73_RS01045	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSB73_RS01100	COG0494	nUDIX hydrolase
FSB73_RS01140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FSB73_RS01160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSB73_RS01165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS01185	COG0436	Aminotransferase
FSB73_RS01190	COG1733	regulation of RNA biosynthetic process
FSB73_RS01200	COG1803	Methylglyoxal synthase
FSB73_RS01215	COG0183	Belongs to the thiolase family
FSB73_RS01220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FSB73_RS01235	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FSB73_RS01240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FSB73_RS01250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSB73_RS01265	COG0022	dehydrogenase e1 component
FSB73_RS01295	COG0702	epimerase
FSB73_RS01300	COG1629	transport
FSB73_RS01305	COG4206	TonB-dependent receptor
FSB73_RS01305	COG1629	transport
FSB73_RS01335	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FSB73_RS01345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS01365	COG4771	TonB-dependent receptor
FSB73_RS01385	COG0800	Aldolase
FSB73_RS01395	COG2755	lipolytic protein G-D-S-L family
FSB73_RS01395	COG0657	acetylesterase activity
FSB73_RS01405	COG1312	Catalyzes the dehydration of D-mannonate
FSB73_RS01430	COG5002	protein histidine kinase activity
FSB73_RS01485	COG2181	nitrate reductase activity
FSB73_RS01485	COG0247	lactate metabolic process
FSB73_RS01530	COG0577	efflux transmembrane transporter activity
FSB73_RS01540	COG0517	IMP dehydrogenase activity
FSB73_RS01540	COG0516	GMP reductase activity
FSB73_RS01560	COG4804	nuclease activity
FSB73_RS01570	COG2890	protein-(glutamine-N5) methyltransferase activity
FSB73_RS01585	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FSB73_RS01595	COG0525	valine-tRNA ligase activity
FSB73_RS01615	COG0791	NLP P60 protein
FSB73_RS01625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSB73_RS01630	COG1090	epimerase
FSB73_RS01650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSB73_RS01650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSB73_RS01670	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FSB73_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS01695	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FSB73_RS01705	COG4948	Mandelate Racemase Muconate Lactonizing
FSB73_RS01715	COG1428	Deoxynucleoside kinase
FSB73_RS01720	COG0180	Tryptophanyl-tRNA synthetase
FSB73_RS01725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FSB73_RS01735	COG2022	thiamine diphosphate biosynthetic process
FSB73_RS01785	COG4251	negative regulation of phosphorylation
FSB73_RS01795	COG2204	response regulator
FSB73_RS01810	COG3387	PFAM Glycoside hydrolase 15-related
FSB73_RS01845	COG1074	ATP-dependent DNA helicase activity
FSB73_RS01850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FSB73_RS01855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSB73_RS01930	COG0359	binds to the 23S rRNA
FSB73_RS01935	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FSB73_RS01940	COG0360	Binds together with S18 to 16S ribosomal RNA
FSB73_RS01945	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FSB73_RS01960	COG0473	3-isopropylmalate dehydrogenase activity
FSB73_RS01985	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FSB73_RS02015	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FSB73_RS02045	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FSB73_RS02050	COG1809	phosphosulfolactate synthase activity
FSB73_RS02065	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FSB73_RS02070	COG0594	ribonuclease P activity
FSB73_RS02080	COG0438	transferase activity, transferring glycosyl groups
FSB73_RS02095	COG3254	rhamnose metabolic process
FSB73_RS02165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FSB73_RS02170	COG4279	zinc finger
FSB73_RS02190	COG2207	Transcriptional regulator
FSB73_RS02260	COG4206	TonB-dependent receptor
FSB73_RS02270	COG2166	iron-sulfur cluster assembly
FSB73_RS02300	COG1858	cytochrome C peroxidase
FSB73_RS02310	COG2132	Multicopper oxidase
FSB73_RS02400	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FSB73_RS02415	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FSB73_RS02420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FSB73_RS02435	COG0259	pyridoxamine-phosphate oxidase activity
FSB73_RS02440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FSB73_RS02455	COG0758	DNA mediated transformation
FSB73_RS02455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSB73_RS02460	COG2095	MarC family integral membrane protein
FSB73_RS02465	COG1252	NADH dehydrogenase
FSB73_RS02520	COG0589	response to stress
FSB73_RS02525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSB73_RS02530	COG2885	chlorophyll binding
FSB73_RS02555	COG1566	PFAM secretion protein HlyD family protein
FSB73_RS02565	COG2267	carboxylic ester hydrolase activity
FSB73_RS02600	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FSB73_RS02615	COG0586	Pfam SNARE associated Golgi protein
FSB73_RS02620	COG1301	dicarboxylic acid transport
FSB73_RS02625	COG0531	amino acid
FSB73_RS02630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FSB73_RS02640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSB73_RS02655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FSB73_RS02660	COG3550	peptidyl-serine autophosphorylation
FSB73_RS02680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FSB73_RS02710	COG1012	belongs to the aldehyde dehydrogenase family
FSB73_RS02760	COG2261	transglycosylase associated protein
FSB73_RS02775	COG1530	ribonuclease E activity
FSB73_RS02830	COG1950	PFAM Membrane protein of
FSB73_RS02840	COG0612	Peptidase, M16
FSB73_RS02865	COG0659	secondary active sulfate transmembrane transporter activity
FSB73_RS02870	COG0577	efflux transmembrane transporter activity
FSB73_RS02900	COG3250	beta-galactosidase activity
FSB73_RS02910	COG0673	inositol 2-dehydrogenase activity
FSB73_RS02960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSB73_RS02995	COG3940	Belongs to the glycosyl hydrolase 43 family
FSB73_RS03005	COG3250	beta-galactosidase activity
FSB73_RS03015	COG3250	beta-galactosidase activity
FSB73_RS03020	COG3250	beta-galactosidase activity
FSB73_RS03030	COG3250	beta-galactosidase activity
FSB73_RS03035	COG3408	Glycogen debranching enzyme
FSB73_RS03045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSB73_RS03075	COG3408	Glycogen debranching enzyme
FSB73_RS03160	COG0702	epimerase
FSB73_RS03165	COG4771	TonB-dependent receptor
FSB73_RS03170	COG0745	RESPONSE REGULATOR receiver
FSB73_RS03175	COG5002	protein histidine kinase activity
FSB73_RS03185	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
FSB73_RS03225	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FSB73_RS03245	COG1858	cytochrome C peroxidase
FSB73_RS03250	COG1690	Belongs to the RtcB family
FSB73_RS03270	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FSB73_RS03360	COG2909	trisaccharide binding
FSB73_RS03365	COG4566	intracellular signal transduction
FSB73_RS03390	COG1136	(ABC) transporter
FSB73_RS03390	COG0577	efflux transmembrane transporter activity
FSB73_RS03400	COG3344	reverse transcriptase
FSB73_RS03445	COG3265	gluconokinase activity
FSB73_RS03450	COG3548	integral membrane protein
FSB73_RS03460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSB73_RS03475	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FSB73_RS03525	COG0516	GMP reductase activity
FSB73_RS03525	COG0517	IMP dehydrogenase activity
FSB73_RS03595	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FSB73_RS03600	COG0228	four-way junction DNA binding
FSB73_RS03605	COG0156	8-amino-7-oxononanoate synthase activity
FSB73_RS03610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSB73_RS03640	COG0577	efflux transmembrane transporter activity
FSB73_RS03645	COG1522	sequence-specific DNA binding
FSB73_RS03680	COG1733	regulation of RNA biosynthetic process
FSB73_RS03700	COG2304	oxidoreductase activity
FSB73_RS03705	COG0481	GTPase activity
FSB73_RS03710	COG3757	hydrolase, family 25
FSB73_RS03720	COG1666	GTP binding
FSB73_RS03735	COG0424	maF-like protein
FSB73_RS03740	COG1136	(ABC) transporter
FSB73_RS03740	COG0577	efflux transmembrane transporter activity
FSB73_RS03770	COG1393	Belongs to the ArsC family
FSB73_RS03775	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FSB73_RS03790	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FSB73_RS03795	COG1663	tetraacyldisaccharide 4'-kinase activity
FSB73_RS03800	COG0557	exoribonuclease II activity
FSB73_RS03810	COG1193	negative regulation of DNA recombination
FSB73_RS03840	COG0793	Belongs to the peptidase S41A family
FSB73_RS03860	COG0438	transferase activity, transferring glycosyl groups
FSB73_RS03870	COG1442	glycosyl transferase family 8
FSB73_RS03870	COG1216	Glycosyl transferase, family 2
FSB73_RS03885	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FSB73_RS03885	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FSB73_RS03955	COG0505	Belongs to the CarA family
FSB73_RS03960	COG1418	mRNA catabolic process
FSB73_RS03965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FSB73_RS03980	COG0776	regulation of translation
FSB73_RS03990	COG0708	Exodeoxyribonuclease III
FSB73_RS03995	COG1181	Belongs to the D-alanine--D-alanine ligase family
FSB73_RS04000	COG1181	Belongs to the D-alanine--D-alanine ligase family
FSB73_RS04005	COG2815	serine threonine protein kinase
FSB73_RS04005	COG0515	serine threonine protein kinase
FSB73_RS04015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FSB73_RS04065	COG0783	Belongs to the Dps family
FSB73_RS04080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FSB73_RS04100	COG4206	TonB-dependent receptor
FSB73_RS04100	COG1629	transport
FSB73_RS04125	COG4771	TonB-dependent receptor
FSB73_RS04140	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FSB73_RS04145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSB73_RS04160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSB73_RS04165	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSB73_RS04175	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FSB73_RS04185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSB73_RS04250	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FSB73_RS04290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSB73_RS04300	COG1538	Outer membrane efflux protein
FSB73_RS04305	COG1902	pentaerythritol trinitrate reductase activity
FSB73_RS04320	COG0577	efflux transmembrane transporter activity
FSB73_RS04385	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FSB73_RS04415	COG0196	riboflavin kinase activity
FSB73_RS04430	COG0297	glycogen (starch) synthase activity
FSB73_RS04435	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FSB73_RS04460	COG0848	biopolymer transport protein
FSB73_RS04465	COG0811	peptide transport
FSB73_RS04515	COG4771	TonB-dependent receptor
FSB73_RS04540	COG1629	transport
FSB73_RS04555	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FSB73_RS04560	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FSB73_RS04565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FSB73_RS04570	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FSB73_RS04575	COG0356	it plays a direct role in the translocation of protons across the membrane
FSB73_RS04590	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FSB73_RS04605	COG1253	flavin adenine dinucleotide binding
FSB73_RS04610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS04650	COG1733	regulation of RNA biosynthetic process
FSB73_RS04675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FSB73_RS04690	COG2177	Part of the ABC transporter FtsEX involved in
FSB73_RS04695	COG0495	leucyl-tRNA aminoacylation
FSB73_RS04720	COG2264	protein methyltransferase activity
FSB73_RS04725	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FSB73_RS04770	COG3457	Alanine racemase
FSB73_RS04780	COG3345	alpha-galactosidase
FSB73_RS04785	COG0416	fatty acid biosynthetic process
FSB73_RS04805	COG3158	transport of potassium into the cell
FSB73_RS04815	COG0047	phosphoribosylformylglycinamidine synthase activity
FSB73_RS04840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FSB73_RS04845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSB73_RS04855	COG0492	ferredoxin-NADP+ reductase activity
FSB73_RS04860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FSB73_RS04890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FSB73_RS04900	COG2003	Belongs to the UPF0758 family
FSB73_RS04935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSB73_RS04945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FSB73_RS04950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FSB73_RS04960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FSB73_RS05005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSB73_RS05010	COG1132	(ABC) transporter
FSB73_RS05015	COG3655	Transcriptional regulator
FSB73_RS05030	COG0154	amidase activity
FSB73_RS05035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FSB73_RS05040	COG3239	Fatty acid desaturase
FSB73_RS05045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FSB73_RS05060	COG0514	ATP-dependent DNA helicase (RecQ)
FSB73_RS05090	COG1528	Iron-storage protein
FSB73_RS05095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FSB73_RS05115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FSB73_RS05120	COG0052	Belongs to the universal ribosomal protein uS2 family
FSB73_RS05125	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSB73_RS05130	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FSB73_RS05190	COG0702	epimerase
FSB73_RS05195	COG1629	transport
FSB73_RS05220	COG0163	prenyltransferase activity
FSB73_RS05230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSB73_RS05245	COG0083	homoserine kinase activity
FSB73_RS05250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FSB73_RS05255	COG5002	protein histidine kinase activity
FSB73_RS05255	COG2205	protein histidine kinase activity
FSB73_RS05255	COG0784	Response regulator, receiver
FSB73_RS05270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSB73_RS05280	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FSB73_RS05285	COG1981	membrane
FSB73_RS05335	COG1610	YqeY-like protein
FSB73_RS05395	COG1960	acyl-CoA dehydrogenase activity
FSB73_RS05400	COG0504	CTP synthase activity
FSB73_RS05415	COG0357	Ribosomal RNA small subunit methyltransferase G
FSB73_RS05420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FSB73_RS05425	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FSB73_RS05440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FSB73_RS05475	COG0443	Heat shock 70 kDa protein
FSB73_RS05500	COG0346	lactoylglutathione lyase activity
FSB73_RS05570	COG2160	L-arabinose isomerase activity
FSB73_RS05575	COG0235	Class ii aldolase
FSB73_RS05580	COG1069	ribulokinase activity
FSB73_RS05585	COG2207	Transcriptional regulator
FSB73_RS05590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSB73_RS05595	COG1012	belongs to the aldehyde dehydrogenase family
FSB73_RS05600	COG1012	belongs to the aldehyde dehydrogenase family
FSB73_RS05615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSB73_RS05620	COG0006	proline dipeptidase activity
FSB73_RS05655	COG0702	epimerase
FSB73_RS05705	COG2910	NAD(P)H-binding
FSB73_RS05740	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FSB73_RS05745	COG0798	PFAM Bile acid sodium symporter
FSB73_RS05755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSB73_RS05775	COG2197	response regulator
FSB73_RS05780	COG0642	Histidine kinase
FSB73_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS05825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSB73_RS05830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FSB73_RS05840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSB73_RS05845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSB73_RS05850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FSB73_RS05855	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FSB73_RS05890	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSB73_RS05890	COG1024	Enoyl-CoA hydratase
FSB73_RS05895	COG2079	MmgE PrpD family protein
FSB73_RS05900	COG0372	Belongs to the citrate synthase family
FSB73_RS05910	COG1024	Enoyl-CoA hydratase
FSB73_RS05965	COG2873	o-acetylhomoserine
FSB73_RS05970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSB73_RS05995	COG2205	protein histidine kinase activity
FSB73_RS06030	COG2186	Transcriptional regulator
FSB73_RS06080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FSB73_RS06085	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FSB73_RS06105	COG4948	Mandelate Racemase Muconate Lactonizing
FSB73_RS06110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FSB73_RS06155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FSB73_RS06165	COG0673	inositol 2-dehydrogenase activity
FSB73_RS06170	COG4221	oxidoreductase activity
FSB73_RS06175	COG1917	Cupin 2, conserved barrel domain protein
FSB73_RS06175	COG4977	sequence-specific DNA binding
FSB73_RS06185	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FSB73_RS06200	COG0314	molybdopterin synthase activity
FSB73_RS06210	COG0243	molybdopterin cofactor binding
FSB73_RS06215	COG0243	molybdopterin cofactor binding
FSB73_RS06245	COG0746	molybdenum cofactor guanylyltransferase activity
FSB73_RS06260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSB73_RS06330	COG0477	Major facilitator Superfamily
FSB73_RS06345	COG2132	Multicopper oxidase
FSB73_RS06380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSB73_RS06395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FSB73_RS06400	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FSB73_RS06415	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FSB73_RS06420	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSB73_RS06425	COG1136	(ABC) transporter
FSB73_RS06430	COG2096	Adenosyltransferase
FSB73_RS06435	COG1136	(ABC) transporter
FSB73_RS06470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FSB73_RS06480	COG0336	Belongs to the RNA methyltransferase TrmD family
FSB73_RS06530	COG4771	TonB-dependent receptor
FSB73_RS06540	COG1595	DNA-templated transcription, initiation
FSB73_RS06545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FSB73_RS06575	COG0583	DNA-binding transcription factor activity
FSB73_RS06585	COG3002	Belongs to the UPF0753 family
FSB73_RS06595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSB73_RS06600	COG0328	RNA-DNA hybrid ribonuclease activity
FSB73_RS06605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FSB73_RS06625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FSB73_RS06640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSB73_RS06650	COG0433	COG0433 Predicted ATPase
FSB73_RS06655	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FSB73_RS06680	COG0824	Thioesterase
FSB73_RS06740	COG0563	adenylate kinase activity
FSB73_RS06775	COG0697	spore germination
FSB73_RS06780	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FSB73_RS06800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FSB73_RS06835	COG0366	Alpha amylase catalytic
FSB73_RS06845	COG0366	Alpha amylase catalytic
FSB73_RS06860	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FSB73_RS06865	COG4206	TonB-dependent receptor
FSB73_RS06865	COG1629	transport
FSB73_RS06900	COG1136	(ABC) transporter
FSB73_RS06900	COG0577	efflux transmembrane transporter activity
FSB73_RS06905	COG0577	efflux transmembrane transporter activity
FSB73_RS06915	COG0577	efflux transmembrane transporter activity
FSB73_RS06920	COG1136	(ABC) transporter
FSB73_RS06930	COG0577	efflux transmembrane transporter activity
FSB73_RS06950	COG3852	Histidine kinase
FSB73_RS06960	COG0300	oxidoreductase activity
FSB73_RS06965	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FSB73_RS06970	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FSB73_RS06990	COG0779	Required for maturation of 30S ribosomal subunits
FSB73_RS06995	COG0195	Participates in both transcription termination and antitermination
FSB73_RS07000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FSB73_RS07005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSB73_RS07020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSB73_RS07045	COG3279	Response regulator of the LytR AlgR family
FSB73_RS07065	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FSB73_RS07070	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FSB73_RS07105	COG0222	ribosome binding
FSB73_RS07110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FSB73_RS07120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FSB73_RS07160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSB73_RS07170	COG1388	LysM domain
FSB73_RS07170	COG0791	NLP P60 protein
FSB73_RS07175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FSB73_RS07175	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FSB73_RS07185	COG3292	Two component regulator propeller
FSB73_RS07185	COG2205	protein histidine kinase activity
FSB73_RS07185	COG0745	RESPONSE REGULATOR receiver
FSB73_RS07185	COG3292	Two component regulator propeller
FSB73_RS07185	COG2205	protein histidine kinase activity
FSB73_RS07185	COG0745	RESPONSE REGULATOR receiver
FSB73_RS07215	COG4948	Mandelate Racemase Muconate Lactonizing
FSB73_RS07230	COG4771	TonB-dependent receptor
FSB73_RS07235	COG4206	TonB-dependent receptor
FSB73_RS07235	COG1629	transport
FSB73_RS07240	COG1629	transport
FSB73_RS07260	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSB73_RS07265	COG4771	TonB-dependent receptor
FSB73_RS07270	COG0702	epimerase
FSB73_RS07295	COG3537	Alpha-1,2-mannosidase
FSB73_RS07310	COG0477	Major facilitator Superfamily
FSB73_RS07375	COG0069	glutamate synthase activity
FSB73_RS07380	COG0009	L-threonylcarbamoyladenylate synthase
FSB73_RS07400	COG0084	hydrolase, TatD family'
FSB73_RS07470	COG4206	TonB-dependent receptor
FSB73_RS07470	COG1629	transport
FSB73_RS07510	COG1082	Xylose isomerase domain protein TIM barrel
FSB73_RS07530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSB73_RS07555	COG1629	transport
FSB73_RS07560	COG3537	Alpha-1,2-mannosidase
FSB73_RS07570	COG0577	efflux transmembrane transporter activity
FSB73_RS07580	COG4771	TonB-dependent receptor
FSB73_RS07600	COG1131	(ABC) transporter
FSB73_RS07610	COG3119	arylsulfatase activity
FSB73_RS07620	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS07670	COG1472	Belongs to the glycosyl hydrolase 3 family
FSB73_RS07685	COG3537	Alpha-1,2-mannosidase
FSB73_RS07690	COG0702	epimerase
FSB73_RS07695	COG4771	TonB-dependent receptor
FSB73_RS07700	COG2814	Major facilitator Superfamily
FSB73_RS07730	COG3507	Belongs to the glycosyl hydrolase 43 family
FSB73_RS07775	COG4206	TonB-dependent receptor
FSB73_RS07775	COG1629	transport
FSB73_RS07815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSB73_RS07820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSB73_RS07825	COG0673	inositol 2-dehydrogenase activity
FSB73_RS07835	COG0110	maltose O-acetyltransferase activity
FSB73_RS07905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSB73_RS07940	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSB73_RS07945	COG1612	heme a metabolic process
FSB73_RS07950	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FSB73_RS07955	COG3668	Plasmid stabilization system
FSB73_RS07960	COG3609	addiction module antidote protein, CC2985 family
FSB73_RS07970	COG0598	Magnesium transport protein CorA
FSB73_RS07980	COG0772	Belongs to the SEDS family
FSB73_RS07985	COG0768	penicillin binding
FSB73_RS08000	COG1077	Cell shape determining protein MreB Mrl
FSB73_RS08020	COG0577	efflux transmembrane transporter activity
FSB73_RS08045	COG3345	alpha-galactosidase
FSB73_RS08055	COG2382	esterase
FSB73_RS08055	COG3693	PFAM glycoside hydrolase, family 10
FSB73_RS08065	COG1501	Belongs to the glycosyl hydrolase 31 family
FSB73_RS08100	COG1501	Belongs to the glycosyl hydrolase 31 family
FSB73_RS08105	COG3693	PFAM glycoside hydrolase, family 10
FSB73_RS08105	COG3507	Belongs to the glycosyl hydrolase 43 family
FSB73_RS08105	COG2382	esterase
FSB73_RS08135	COG0702	epimerase
FSB73_RS08150	COG4771	TonB-dependent receptor
FSB73_RS08160	COG1629	transport
FSB73_RS08165	COG3661	Belongs to the glycosyl hydrolase 67 family
FSB73_RS08180	COG3507	Belongs to the glycosyl hydrolase 43 family
FSB73_RS08190	COG2814	Major facilitator Superfamily
FSB73_RS08190	COG0477	Major facilitator Superfamily
FSB73_RS08195	COG2814	Major facilitator Superfamily
FSB73_RS08195	COG0477	Major facilitator Superfamily
FSB73_RS08200	COG2115	Belongs to the xylose isomerase family
FSB73_RS08205	COG1070	Carbohydrate kinase
FSB73_RS08210	COG1609	Transcriptional regulator
FSB73_RS08235	COG1472	Belongs to the glycosyl hydrolase 3 family
FSB73_RS08250	COG0346	lactoylglutathione lyase activity
FSB73_RS08270	COG2235	arginine
FSB73_RS08275	COG2235	arginine
FSB73_RS08300	COG0335	large ribosomal subunit rRNA binding
FSB73_RS08315	COG0436	Aminotransferase
FSB73_RS08325	COG1760	l-serine dehydratase
FSB73_RS08335	COG1234	tRNA 3'-trailer cleavage
FSB73_RS08340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FSB73_RS08345	COG2205	protein histidine kinase activity
FSB73_RS08345	COG2205	protein histidine kinase activity
FSB73_RS08345	COG3292	Two component regulator propeller
FSB73_RS08345	COG3292	Two component regulator propeller
FSB73_RS08345	COG0745	RESPONSE REGULATOR receiver
FSB73_RS08345	COG0745	RESPONSE REGULATOR receiver
FSB73_RS08370	COG1501	Belongs to the glycosyl hydrolase 31 family
FSB73_RS08375	COG1501	Belongs to the glycosyl hydrolase 31 family
FSB73_RS08380	COG1501	Belongs to the glycosyl hydrolase 31 family
FSB73_RS08385	COG1629	transport
FSB73_RS08425	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSB73_RS08445	COG0673	inositol 2-dehydrogenase activity
FSB73_RS08460	COG2211	Major facilitator Superfamily
FSB73_RS08480	COG2217	Heavy metal translocating P-type atpase
FSB73_RS08495	COG0215	cysteine-tRNA ligase activity
FSB73_RS08505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSB73_RS08525	COG0571	ribonuclease III activity
FSB73_RS08530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSB73_RS08535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSB73_RS08560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FSB73_RS08565	COG2315	Protein conserved in bacteria
FSB73_RS08590	COG1629	transport
FSB73_RS08600	COG0326	Molecular chaperone. Has ATPase activity
FSB73_RS08620	COG0592	DNA-directed DNA polymerase activity
FSB73_RS08630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSB73_RS08650	COG1215	transferase activity, transferring glycosyl groups
FSB73_RS08670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSB73_RS08675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSB73_RS08680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSB73_RS08735	COG0387	Pfam Sodium calcium exchanger
FSB73_RS08745	COG1349	DNA-binding transcription factor activity
FSB73_RS08750	COG1335	isochorismatase
FSB73_RS08770	COG3940	Belongs to the glycosyl hydrolase 43 family
FSB73_RS08775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSB73_RS08785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSB73_RS08790	COG3537	Alpha-1,2-mannosidase
FSB73_RS08810	COG2207	Transcriptional regulator
FSB73_RS08845	COG1022	Amp-dependent synthetase and ligase
FSB73_RS08850	COG0151	Belongs to the GarS family
FSB73_RS08865	COG2076	Multidrug Resistance protein
FSB73_RS08875	COG1597	lipid kinase activity
FSB73_RS08885	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FSB73_RS08895	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FSB73_RS08900	COG0445	tRNA wobble uridine modification
FSB73_RS08910	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FSB73_RS08915	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSB73_RS08935	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FSB73_RS08970	COG1629	transport
FSB73_RS08970	COG4206	TonB-dependent receptor
FSB73_RS09000	COG1629	transport
FSB73_RS09015	COG2884	Cell division ATP-binding protein ftsE
FSB73_RS09030	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FSB73_RS09035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FSB73_RS09060	COG0113	porphobilinogen synthase activity
FSB73_RS09065	COG0408	coproporphyrinogen oxidase activity
FSB73_RS09080	COG0181	hydroxymethylbilane synthase activity
FSB73_RS09085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FSB73_RS09090	COG1940	carbohydrate kinase activity
FSB73_RS09125	COG0025	NhaP-type Na H and K H
FSB73_RS09130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FSB73_RS09135	COG0302	gtp cyclohydrolase
FSB73_RS09175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FSB73_RS09180	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FSB73_RS09195	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FSB73_RS09230	COG0561	phosphatase activity
FSB73_RS09235	COG1629	transport
FSB73_RS09235	COG4206	TonB-dependent receptor
FSB73_RS09250	COG3011	Protein conserved in bacteria
FSB73_RS09265	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FSB73_RS09275	COG0537	adenosine 5'-monophosphoramidase activity
FSB73_RS09280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSB73_RS09280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FSB73_RS09290	COG0402	S-adenosylhomocysteine deaminase activity
FSB73_RS09295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSB73_RS09300	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FSB73_RS09305	COG0688	phosphatidylethanolamine metabolic process
FSB73_RS09310	COG4589	Belongs to the CDS family
FSB73_RS09320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FSB73_RS09325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FSB73_RS09355	COG3408	Glycogen debranching enzyme
FSB73_RS09360	COG3537	Alpha-1,2-mannosidase
FSB73_RS09370	COG1629	transport
FSB73_RS09370	COG4206	TonB-dependent receptor
FSB73_RS09380	COG1609	Transcriptional regulator
FSB73_RS09385	COG3408	Glycogen debranching enzyme
FSB73_RS09385	COG3119	arylsulfatase activity
FSB73_RS09390	COG3119	arylsulfatase activity
FSB73_RS09390	COG3408	Glycogen debranching enzyme
FSB73_RS09480	COG3347	Dehydrogenase
FSB73_RS09480	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS09485	COG4952	isomerase
FSB73_RS09490	COG1070	Carbohydrate kinase
FSB73_RS09495	COG1304	FMN binding
FSB73_RS09500	COG4771	TonB-dependent receptor
FSB73_RS09505	COG0702	epimerase
FSB73_RS09560	COG3254	rhamnose metabolic process
FSB73_RS09565	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FSB73_RS09580	COG4733	cellulase activity
FSB73_RS09590	COG4771	TonB-dependent receptor
FSB73_RS09595	COG0702	epimerase
FSB73_RS09610	COG1629	transport
FSB73_RS09610	COG4206	TonB-dependent receptor
FSB73_RS09615	COG1629	transport
FSB73_RS09630	COG2755	lipolytic protein G-D-S-L family
FSB73_RS09635	COG2755	lipolytic protein G-D-S-L family
FSB73_RS09640	COG3401	FG-GAP repeat protein
FSB73_RS09645	COG3250	beta-galactosidase activity
FSB73_RS09650	COG3250	beta-galactosidase activity
FSB73_RS09665	COG0702	epimerase
FSB73_RS09675	COG3279	Response regulator of the LytR AlgR family
FSB73_RS09680	COG3275	phosphorelay sensor kinase activity
FSB73_RS09690	COG2885	chlorophyll binding
FSB73_RS09705	COG4206	TonB-dependent receptor
FSB73_RS09705	COG1629	transport
FSB73_RS09715	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSB73_RS09720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSB73_RS09730	COG0649	NAD binding
FSB73_RS09735	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FSB73_RS09745	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FSB73_RS09750	COG1034	ATP synthesis coupled electron transport
FSB73_RS09755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FSB73_RS09765	COG0839	Belongs to the complex I subunit 6 family
FSB73_RS09785	COG1007	ATP synthesis coupled electron transport
FSB73_RS09800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FSB73_RS09825	COG3292	Two component regulator propeller
FSB73_RS09825	COG0745	RESPONSE REGULATOR receiver
FSB73_RS09825	COG2205	protein histidine kinase activity
FSB73_RS09845	COG1629	transport
FSB73_RS09845	COG4206	TonB-dependent receptor
FSB73_RS09850	COG4206	TonB-dependent receptor
FSB73_RS09850	COG1629	transport
FSB73_RS09880	COG3250	beta-galactosidase activity
FSB73_RS09890	COG0579	oxidoreductase
FSB73_RS09915	COG2326	polyphosphate kinase activity
FSB73_RS09920	COG1970	mechanosensitive ion channel activity
FSB73_RS09925	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSB73_RS09945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSB73_RS09955	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSB73_RS09960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FSB73_RS09965	COG1956	GAF domain-containing protein
FSB73_RS09970	COG3279	Response regulator of the LytR AlgR family
FSB73_RS09975	COG3275	phosphorelay sensor kinase activity
FSB73_RS09980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FSB73_RS09985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSB73_RS09990	COG3876	Protein conserved in bacteria
FSB73_RS10005	COG1418	mRNA catabolic process
FSB73_RS10010	COG1217	gtp-binding protein TYPA
FSB73_RS10025	COG0233	cytoplasmic translational termination
FSB73_RS10030	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FSB73_RS10035	COG0126	phosphoglycerate kinase activity
FSB73_RS10050	COG0640	Transcriptional regulator
FSB73_RS10055	COG1214	PFAM Peptidase M22, glycoprotease
FSB73_RS10060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FSB73_RS10070	COG0437	4 iron, 4 sulfur cluster binding
FSB73_RS10095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FSB73_RS10100	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FSB73_RS10105	COG0109	protoheme IX farnesyltransferase activity
FSB73_RS10110	COG1845	cytochrome c oxidase, subunit III
FSB73_RS10115	COG1845	cytochrome c oxidase, subunit III
FSB73_RS10150	COG2322	membrane
FSB73_RS10155	COG3118	belongs to the thioredoxin family
FSB73_RS10160	COG0463	Glycosyl transferase, family 2
FSB73_RS10165	COG2176	DNA-directed DNA polymerase activity
FSB73_RS10170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSB73_RS10200	COG2363	Small membrane protein
FSB73_RS10205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FSB73_RS10210	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FSB73_RS10215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FSB73_RS10225	COG0497	DNA recombination
FSB73_RS10240	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FSB73_RS10245	COG0017	Asparaginyl-tRNA synthetase
FSB73_RS10275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSB73_RS10290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FSB73_RS10295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FSB73_RS10355	COG2001	Belongs to the MraZ family
FSB73_RS10370	COG1733	regulation of RNA biosynthetic process
FSB73_RS10380	COG4771	TonB-dependent receptor
FSB73_RS10490	COG3119	arylsulfatase activity
FSB73_RS10495	COG3507	Belongs to the glycosyl hydrolase 43 family
FSB73_RS10510	COG0702	epimerase
FSB73_RS10515	COG4771	TonB-dependent receptor
FSB73_RS10530	COG2205	protein histidine kinase activity
FSB73_RS10530	COG3292	Two component regulator propeller
FSB73_RS10530	COG0745	RESPONSE REGULATOR receiver
FSB73_RS10535	COG0745	RESPONSE REGULATOR receiver
FSB73_RS10535	COG2205	protein histidine kinase activity
FSB73_RS10535	COG3292	Two component regulator propeller
FSB73_RS10560	COG0051	transcription antitermination factor activity, RNA binding
FSB73_RS10570	COG0088	Forms part of the polypeptide exit tunnel
FSB73_RS10575	COG0089	rRNA binding
FSB73_RS10585	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FSB73_RS10590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FSB73_RS10595	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FSB73_RS10600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FSB73_RS10605	COG0255	Belongs to the universal ribosomal protein uL29 family
FSB73_RS10610	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FSB73_RS10615	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FSB73_RS10620	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FSB73_RS10630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FSB73_RS10635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSB73_RS10640	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSB73_RS10645	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FSB73_RS10650	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSB73_RS10655	COG1841	ribosomal large subunit assembly
FSB73_RS10660	COG0200	Binds to the 23S rRNA
FSB73_RS10675	COG2081	HI0933 family
FSB73_RS10705	COG0415	Belongs to the DNA photolyase family
FSB73_RS10720	COG0714	Associated with various cellular activities
FSB73_RS10760	COG4585	Histidine kinase
FSB73_RS10790	COG0321	lipoyl(octanoyl) transferase activity
FSB73_RS10800	COG4206	TonB-dependent receptor
FSB73_RS10815	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FSB73_RS10820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FSB73_RS10825	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FSB73_RS10825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSB73_RS10835	COG1183	phosphatidylcholine synthase activity
FSB73_RS10840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSB73_RS10850	COG1162	GTPase activity
FSB73_RS10870	COG1138	Cytochrome C-type biogenesis protein
FSB73_RS10880	COG3345	alpha-galactosidase
FSB73_RS10890	COG3292	Two component regulator propeller
FSB73_RS10890	COG2205	protein histidine kinase activity
FSB73_RS10890	COG0745	RESPONSE REGULATOR receiver
FSB73_RS10890	COG2205	protein histidine kinase activity
FSB73_RS10890	COG0745	RESPONSE REGULATOR receiver
FSB73_RS10890	COG3292	Two component regulator propeller
FSB73_RS10895	COG0745	RESPONSE REGULATOR receiver
FSB73_RS10895	COG2205	protein histidine kinase activity
FSB73_RS10895	COG3292	Two component regulator propeller
FSB73_RS10900	COG1629	transport
FSB73_RS10900	COG4206	TonB-dependent receptor
FSB73_RS10905	COG4771	TonB-dependent receptor
FSB73_RS10915	COG0702	epimerase
FSB73_RS10920	COG3507	Belongs to the glycosyl hydrolase 43 family
FSB73_RS10930	COG3507	Belongs to the glycosyl hydrolase 43 family
FSB73_RS10935	COG1629	transport
FSB73_RS10965	COG3250	beta-galactosidase activity
FSB73_RS10985	COG4771	TonB-dependent receptor
FSB73_RS11005	COG3250	beta-galactosidase activity
FSB73_RS11010	COG3250	beta-galactosidase activity
FSB73_RS11025	COG3258	Cytochrome c
FSB73_RS11030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSB73_RS11040	COG0564	pseudouridine synthase activity
FSB73_RS11045	COG1047	Peptidyl-prolyl cis-trans
FSB73_RS11050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS11075	COG1556	Lactate utilization protein
FSB73_RS11080	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSB73_RS11090	COG0668	transmembrane transport
FSB73_RS11100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FSB73_RS11125	COG0616	signal peptide processing
FSB73_RS11130	COG0616	signal peptide processing
FSB73_RS11135	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FSB73_RS11135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FSB73_RS11140	COG0805	protein transport
FSB73_RS11145	COG0604	alcohol dehydrogenase
FSB73_RS11165	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FSB73_RS11165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FSB73_RS11175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSB73_RS11195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS11210	COG2204	response regulator
FSB73_RS11215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FSB73_RS11225	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSB73_RS11235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSB73_RS11265	COG0577	efflux transmembrane transporter activity
FSB73_RS11270	COG0724	RNA recognition motif
FSB73_RS11275	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FSB73_RS11385	COG1484	DNA-dependent DNA replication
FSB73_RS11395	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FSB73_RS11400	COG2086	electron transfer activity
FSB73_RS11415	COG1131	(ABC) transporter
FSB73_RS11430	COG1136	(ABC) transporter
FSB73_RS11485	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FSB73_RS11490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FSB73_RS11500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSB73_RS11510	COG1482	cell wall glycoprotein biosynthetic process
FSB73_RS11520	COG4974	Belongs to the 'phage' integrase family
FSB73_RS11550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FSB73_RS11565	COG0149	triose-phosphate isomerase activity
FSB73_RS11605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSB73_RS11615	COG1999	signal sequence binding
FSB73_RS11625	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FSB73_RS11675	COG4771	TonB-dependent receptor
FSB73_RS11725	COG3119	arylsulfatase activity
FSB73_RS11765	COG4771	TonB-dependent receptor
FSB73_RS11770	COG4771	TonB-dependent receptor
FSB73_RS11870	COG3119	arylsulfatase activity
FSB73_RS11875	COG3279	Response regulator of the LytR AlgR family
FSB73_RS11935	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FSB73_RS11960	COG3250	beta-galactosidase activity
FSB73_RS12010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSB73_RS12060	COG4206	TonB-dependent receptor
FSB73_RS12060	COG1629	transport
FSB73_RS12065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS12095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSB73_RS12105	COG0129	dihydroxy-acid dehydratase activity
FSB73_RS12140	COG0251	oxidation-reduction process
FSB73_RS12245	COG3345	alpha-galactosidase
FSB73_RS12250	COG0339	signal peptide processing
FSB73_RS12270	COG2706	6-phosphogluconolactonase activity
FSB73_RS12290	COG0657	acetylesterase activity
FSB73_RS12295	COG1619	proteins homologs of microcin C7 resistance protein MccF
FSB73_RS12300	COG1619	proteins homologs of microcin C7 resistance protein MccF
FSB73_RS12315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FSB73_RS12340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FSB73_RS12345	COG0632	four-way junction helicase activity
FSB73_RS12375	COG0746	molybdenum cofactor guanylyltransferase activity
FSB73_RS12380	COG0038	chloride channel
FSB73_RS12385	COG1522	sequence-specific DNA binding
FSB73_RS12420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FSB73_RS12430	COG0556	nucleotide-excision repair
FSB73_RS12470	COG3852	Histidine kinase
FSB73_RS12480	COG0175	sulfate reduction
FSB73_RS12485	COG0175	sulfate reduction
FSB73_RS12495	COG1648	precorrin-2 dehydrogenase activity
FSB73_RS12495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSB73_RS12500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FSB73_RS12510	COG0730	response to heat
FSB73_RS12575	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FSB73_RS12580	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FSB73_RS12585	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FSB73_RS12595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSB73_RS12600	COG0202	RNA polymerase activity
FSB73_RS12605	COG0203	ribosomal protein L17
FSB73_RS12620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSB73_RS12635	COG1704	LemA family
FSB73_RS12655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FSB73_RS12665	COG0512	Glutamine amidotransferase of anthranilate synthase
FSB73_RS12670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FSB73_RS12675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FSB73_RS12695	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FSB73_RS12695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FSB73_RS12700	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSB73_RS12735	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FSB73_RS12740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSB73_RS12750	COG0439	Biotin carboxylase
FSB73_RS12760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FSB73_RS12765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FSB73_RS12800	COG0071	Belongs to the small heat shock protein (HSP20) family
FSB73_RS12810	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FSB73_RS12825	COG0583	DNA-binding transcription factor activity
FSB73_RS12840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FSB73_RS12900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FSB73_RS12920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSB73_RS12930	COG1194	a g-specific adenine glycosylase
FSB73_RS12950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FSB73_RS12960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FSB73_RS12970	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FSB73_RS12990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FSB73_RS12995	COG1136	(ABC) transporter
FSB73_RS12995	COG0577	efflux transmembrane transporter activity
FSB73_RS13000	COG0577	efflux transmembrane transporter activity
FSB73_RS13000	COG1136	(ABC) transporter
FSB73_RS13005	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSB73_RS13015	COG0268	Binds directly to 16S ribosomal RNA
FSB73_RS13025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSB73_RS13025	COG0519	Catalyzes the synthesis of GMP from XMP
FSB73_RS13065	COG5002	protein histidine kinase activity
FSB73_RS13065	COG3850	Histidine kinase
FSB73_RS13070	COG0745	RESPONSE REGULATOR receiver
FSB73_RS13115	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FSB73_RS13140	COG3842	ATPase activity
FSB73_RS13165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FSB73_RS13180	COG0431	NADPH-dependent FMN reductase
FSB73_RS13195	COG1501	Belongs to the glycosyl hydrolase 31 family
FSB73_RS13215	COG3275	phosphorelay sensor kinase activity
FSB73_RS13225	COG2755	lipolytic protein G-D-S-L family
FSB73_RS13225	COG0657	acetylesterase activity
FSB73_RS13265	COG0366	Alpha amylase catalytic
FSB73_RS13290	COG0583	DNA-binding transcription factor activity
FSB73_RS13295	COG2855	membrane
FSB73_RS13300	COG2084	Dehydrogenase
FSB73_RS13310	COG2986	histidine ammonia-lyase
FSB73_RS13320	COG1228	amidohydrolase
FSB73_RS13355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FSB73_RS13365	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSB73_RS13385	COG2154	pterin-4-alpha-carbinolamine dehydratase
FSB73_RS13425	COG0589	response to stress
FSB73_RS13470	COG2027	D-alanyl-D-alanine carboxypeptidase
FSB73_RS13475	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FSB73_RS13480	COG1959	2 iron, 2 sulfur cluster binding
FSB73_RS13500	COG0860	N-Acetylmuramoyl-L-alanine amidase
FSB73_RS13515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FSB73_RS13540	COG0714	Associated with various cellular activities
FSB73_RS13545	COG2226	methyltransferase
FSB73_RS13580	COG4221	oxidoreductase activity
FSB73_RS13590	COG2321	neutral zinc metallopeptidase
FSB73_RS13600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FSB73_RS13605	COG0193	aminoacyl-tRNA hydrolase activity
FSB73_RS13615	COG1289	transmembrane transporter activity
FSB73_RS13645	COG0194	GDP metabolic process
FSB73_RS13655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FSB73_RS13665	COG2226	methyltransferase
FSB73_RS13670	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS13710	COG0284	orotidine-5'-phosphate decarboxylase activity
FSB73_RS13740	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSB73_RS13745	COG1058	Belongs to the CinA family
FSB73_RS13745	COG1546	Belongs to the CinA family
FSB73_RS13760	COG0442	prolyl-tRNA aminoacylation
FSB73_RS13775	COG0527	aspartate kinase activity
FSB73_RS13780	COG1131	(ABC) transporter
FSB73_RS13790	COG0494	nUDIX hydrolase
FSB73_RS13800	COG0531	amino acid
FSB73_RS13810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FSB73_RS13840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FSB73_RS13860	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FSB73_RS13870	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FSB73_RS13870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FSB73_RS13875	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FSB73_RS13880	COG2171	N-acyltransferase activity
FSB73_RS13885	COG0009	L-threonylcarbamoyladenylate synthase
FSB73_RS13895	COG0306	phosphate transporter
FSB73_RS13905	COG1629	transport
FSB73_RS13935	COG0673	inositol 2-dehydrogenase activity
FSB73_RS13950	COG3958	Transketolase
FSB73_RS14000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSB73_RS14010	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FSB73_RS14015	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSB73_RS14025	COG0316	Belongs to the HesB IscA family
FSB73_RS14030	COG0719	Fe-S assembly protein
FSB73_RS14035	COG0396	ATPase activity
FSB73_RS14040	COG0719	Fe-S assembly protein
FSB73_RS14050	COG2166	iron-sulfur cluster assembly
FSB73_RS14055	COG2151	metal-sulfur cluster biosynthetic enzyme
FSB73_RS14065	COG1609	Transcriptional regulator
FSB73_RS14070	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FSB73_RS14090	COG0700	Nucleoside recognition
FSB73_RS14100	COG0205	6-phosphofructokinase activity
FSB73_RS14155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FSB73_RS14160	COG0681	Belongs to the peptidase S26 family
FSB73_RS14220	COG1629	transport
FSB73_RS14260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FSB73_RS14270	COG0738	Major facilitator superfamily
FSB73_RS14275	COG3254	rhamnose metabolic process
FSB73_RS14280	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS14285	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSB73_RS14290	COG3618	amidohydrolase
FSB73_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS14300	COG2721	sulfolactate sulfo-lyase activity
FSB73_RS14310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FSB73_RS14360	COG0561	phosphatase activity
FSB73_RS14375	COG2755	lipolytic protein G-D-S-L family
FSB73_RS14405	COG2755	lipolytic protein G-D-S-L family
FSB73_RS14425	COG4771	TonB-dependent receptor
FSB73_RS14430	COG4771	TonB-dependent receptor
FSB73_RS14435	COG0702	epimerase
FSB73_RS14450	COG0246	Mannitol dehydrogenase
FSB73_RS14465	COG0745	RESPONSE REGULATOR receiver
FSB73_RS14465	COG2205	protein histidine kinase activity
FSB73_RS14465	COG3292	Two component regulator propeller
FSB73_RS14470	COG1879	ABC-type sugar transport system periplasmic component
FSB73_RS14505	COG1621	beta-fructofuranosidase activity
FSB73_RS14510	COG3118	belongs to the thioredoxin family
FSB73_RS14525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSB73_RS14535	COG3279	Response regulator of the LytR AlgR family
FSB73_RS14540	COG3275	phosphorelay sensor kinase activity
FSB73_RS14545	COG1136	(ABC) transporter
FSB73_RS14545	COG0577	efflux transmembrane transporter activity
FSB73_RS14555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSB73_RS14565	COG1629	transport
FSB73_RS14565	COG4206	TonB-dependent receptor
FSB73_RS14570	COG0702	epimerase
FSB73_RS14580	COG0702	epimerase
FSB73_RS14585	COG4771	TonB-dependent receptor
FSB73_RS14620	COG3537	Alpha-1,2-mannosidase
FSB73_RS14625	COG1321	iron dependent repressor
FSB73_RS14625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSB73_RS14640	COG0045	succinate-CoA ligase (ADP-forming) activity
FSB73_RS14645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FSB73_RS14650	COG0538	isocitrate dehydrogenase activity
FSB73_RS14660	COG0285	dihydrofolate synthase activity
FSB73_RS14695	COG2244	polysaccharide biosynthetic process
FSB73_RS14720	COG1649	PFAM Uncharacterised BCR, COG1649
FSB73_RS14775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSB73_RS14785	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FSB73_RS14795	COG1940	carbohydrate kinase activity
FSB73_RS14845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FSB73_RS14850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FSB73_RS14875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FSB73_RS14880	COG0653	protein targeting
FSB73_RS14890	COG1476	TRANSCRIPTIONal
FSB73_RS14900	COG2378	regulation of single-species biofilm formation
FSB73_RS14905	COG1668	transmembrane transport
FSB73_RS14910	COG4152	abc transporter atp-binding protein
FSB73_RS14915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSB73_RS14920	COG1611	Belongs to the LOG family
FSB73_RS14935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FSB73_RS14940	COG0482	sulfurtransferase activity
FSB73_RS14965	COG2885	chlorophyll binding
FSB73_RS14965	COG3047	cAMP biosynthetic process
FSB73_RS14990	COG1104	cysteine desulfurase activity
FSB73_RS15000	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FSB73_RS15005	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FSB73_RS15010	COG1739	Uncharacterized protein family UPF0029
FSB73_RS15015	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSB73_RS15015	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSB73_RS15040	COG1381	Involved in DNA repair and RecF pathway recombination
FSB73_RS15050	COG0527	aspartate kinase activity
FSB73_RS15120	COG2239	Acts as a magnesium transporter
FSB73_RS15180	COG2860	membrane
FSB73_RS15185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSB73_RS15215	COG0540	Belongs to the ATCase OTCase family
FSB73_RS15220	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FSB73_RS15230	COG4585	Histidine kinase
FSB73_RS15295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSB73_RS15310	COG0148	phosphopyruvate hydratase activity
FSB73_RS15320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSB73_RS15340	COG3152	Membrane
FSB73_RS15345	COG0077	Prephenate dehydratase
FSB73_RS15350	COG0436	Aminotransferase
FSB73_RS15360	COG0513	Belongs to the DEAD box helicase family
FSB73_RS15365	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FSB73_RS15395	COG3590	peptidase
FSB73_RS15405	COG0531	amino acid
FSB73_RS15415	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FSB73_RS15425	COG1252	NADH dehydrogenase
FSB73_RS15440	COG1388	LysM domain
FSB73_RS15440	COG0791	NLP P60 protein
FSB73_RS15450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSB73_RS15470	COG0671	phosphoesterase, PA-phosphatase related
FSB73_RS15475	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FSB73_RS15490	COG0107	imidazoleglycerol-phosphate synthase activity
FSB73_RS15500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS15505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSB73_RS15510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FSB73_RS15515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FSB73_RS15550	COG0628	permease
FSB73_RS15560	COG0463	Glycosyl transferase, family 2
FSB73_RS15570	COG2151	metal-sulfur cluster biosynthetic enzyme
FSB73_RS15590	COG0010	Belongs to the arginase family
FSB73_RS15605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FSB73_RS15610	COG3360	Dodecin
FSB73_RS15620	COG0166	Belongs to the GPI family
FSB73_RS15635	COG1968	undecaprenyl-diphosphatase activity
FSB73_RS15640	COG2270	Major facilitator Superfamily
FSB73_RS15645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS15655	COG2264	protein methyltransferase activity
FSB73_RS15675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSB73_RS15675	COG1587	Uroporphyrinogen-III synthase
FSB73_RS15680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSB73_RS15685	COG2146	nitrite reductase [NAD(P)H] activity
FSB73_RS15685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSB73_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS15725	COG0539	negative regulation of cytoplasmic translation
FSB73_RS15725	COG2183	response to ionizing radiation
FSB73_RS15735	COG1166	arginine decarboxylase activity
FSB73_RS15740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FSB73_RS15745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FSB73_RS15750	COG0038	chloride channel
FSB73_RS15755	COG1054	Belongs to the UPF0176 family
FSB73_RS15790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSB73_RS15805	COG0037	tRNA processing
FSB73_RS15820	COG0022	dehydrogenase e1 component
FSB73_RS15820	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSB73_RS15855	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FSB73_RS15865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FSB73_RS15890	COG0706	membrane insertase activity
FSB73_RS15920	COG1396	sequence-specific DNA binding
FSB73_RS15925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FSB73_RS15940	COG2989	Protein conserved in bacteria
FSB73_RS15960	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FSB73_RS15970	COG3250	beta-galactosidase activity
FSB73_RS15980	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FSB73_RS15990	COG0552	protein localization to endoplasmic reticulum
FSB73_RS16030	COG1518	maintenance of DNA repeat elements
FSB73_RS16035	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FSB73_RS16045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSB73_RS16055	COG1073	alpha beta
FSB73_RS16085	COG4206	TonB-dependent receptor
FSB73_RS16085	COG1629	transport
FSB73_RS16100	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FSB73_RS16105	COG2272	Belongs to the type-B carboxylesterase lipase family
FSB73_RS16110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSB73_RS16115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSB73_RS16120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FSB73_RS16185	COG3279	Response regulator of the LytR AlgR family
FSB73_RS16190	COG3275	phosphorelay sensor kinase activity
FSB73_RS16195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FSB73_RS16200	COG1674	ftsk spoiiie
FSB73_RS16205	COG1607	acyl-coa hydrolase
FSB73_RS16225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FSB73_RS16240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSB73_RS16245	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FSB73_RS16255	COG0159	tryptophan synthase activity
FSB73_RS16275	COG0135	phosphoribosylanthranilate isomerase activity
FSB73_RS16280	COG0134	indole-3-glycerol-phosphate synthase activity
FSB73_RS16285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FSB73_RS16290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FSB73_RS16290	COG0512	Glutamine amidotransferase of anthranilate synthase
FSB73_RS16295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FSB73_RS16355	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FSB73_RS16365	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FSB73_RS16375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSB73_RS16380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FSB73_RS16385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FSB73_RS16390	COG2045	Belongs to the ComB family
FSB73_RS16410	COG0583	DNA-binding transcription factor activity
FSB73_RS16415	COG0745	RESPONSE REGULATOR receiver
FSB73_RS16420	COG5002	protein histidine kinase activity
FSB73_RS16435	COG1472	Belongs to the glycosyl hydrolase 3 family
FSB73_RS16440	COG1595	DNA-templated transcription, initiation
FSB73_RS16460	COG0531	amino acid
FSB73_RS16480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FSB73_RS16480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FSB73_RS16490	COG3459	Glycosyltransferase 36 associated
FSB73_RS16495	COG3459	Glycosyltransferase 36 associated
FSB73_RS16500	COG2211	Major facilitator Superfamily
FSB73_RS16510	COG0514	ATP-dependent DNA helicase (RecQ)
FSB73_RS16515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FSB73_RS16515	COG0517	IMP dehydrogenase activity
FSB73_RS16525	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS16530	COG1733	regulation of RNA biosynthetic process
FSB73_RS16560	COG4771	TonB-dependent receptor
FSB73_RS16565	COG0702	epimerase
FSB73_RS16570	COG2186	Transcriptional regulator
FSB73_RS16575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSB73_RS16585	COG1506	peptidase
FSB73_RS16585	COG0823	Involved in the tonB-independent uptake of proteins
FSB73_RS16590	COG0705	Rhomboid family
FSB73_RS16595	COG0528	UMP kinase activity
FSB73_RS16605	COG0067	glutamate synthase
FSB73_RS16605	COG0070	glutamate synthase
FSB73_RS16605	COG0069	glutamate synthase activity
FSB73_RS16610	COG0386	Belongs to the glutathione peroxidase family
FSB73_RS16630	COG0657	acetylesterase activity
FSB73_RS16640	COG1205	dead DEAH box helicase
FSB73_RS16640	COG1111	helicase
FSB73_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS16740	COG2602	Beta-lactamase
FSB73_RS16760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSB73_RS16765	COG5492	domain, Protein
FSB73_RS16780	COG3292	Two component regulator propeller
FSB73_RS16780	COG0745	RESPONSE REGULATOR receiver
FSB73_RS16780	COG2205	protein histidine kinase activity
FSB73_RS16785	COG3537	Alpha-1,2-mannosidase
FSB73_RS16830	COG1629	transport
FSB73_RS16835	COG4771	TonB-dependent receptor
FSB73_RS16840	COG0561	phosphatase activity
FSB73_RS16860	COG0484	heat shock protein binding
FSB73_RS16865	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FSB73_RS16870	COG0545	Peptidyl-prolyl cis-trans isomerase
FSB73_RS16880	COG0124	histidyl-tRNA synthetase
FSB73_RS16885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSB73_RS16900	COG0131	Imidazoleglycerol-phosphate dehydratase
FSB73_RS16915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSB73_RS16920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSB73_RS16925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSB73_RS16940	COG3547	Transposase (IS116 IS110 IS902 family)
FSB73_RS16945	COG3345	alpha-galactosidase
FSB73_RS16955	COG2942	2-epimerase
FSB73_RS16960	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FSB73_RS16985	COG1764	response to oxidative stress
FSB73_RS16990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FSB73_RS17000	COG0667	Aldo Keto reductase
FSB73_RS17005	COG2255	four-way junction helicase activity
FSB73_RS17010	COG0038	chloride channel
FSB73_RS17035	COG0544	peptidyl-prolyl cis-trans isomerase activity
FSB73_RS17050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FSB73_RS17095	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FSB73_RS17100	COG0667	Aldo Keto reductase
FSB73_RS17125	COG2814	Major facilitator Superfamily
FSB73_RS17135	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FSB73_RS17145	COG0489	protein tyrosine kinase activity
FSB73_RS17155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FSB73_RS17205	COG0191	fructose-bisphosphate aldolase activity
FSB73_RS17220	COG0601	transmembrane transport
FSB73_RS17250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSB73_RS17275	COG1396	sequence-specific DNA binding
FSB73_RS17285	COG0492	ferredoxin-NADP+ reductase activity
FSB73_RS17295	COG3547	Transposase (IS116 IS110 IS902 family)
FSB73_RS17330	COG0281	malic enzyme
FSB73_RS17330	COG0280	phosphate acetyltransferase
FSB73_RS17335	COG1473	amidohydrolase
FSB73_RS17340	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FSB73_RS17345	COG0023	Translation Initiation Factor
FSB73_RS17365	COG0488	(ABC) transporter
FSB73_RS17370	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FSB73_RS17400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSB73_RS17405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSB73_RS17410	COG0066	3-isopropylmalate dehydratase activity
FSB73_RS17415	COG1119	ATPase activity
FSB73_RS17420	COG1119	ATPase activity
FSB73_RS17425	COG0473	3-isopropylmalate dehydrogenase activity
FSB73_RS17430	COG0129	dihydroxy-acid dehydratase activity
FSB73_RS17435	COG0028	Belongs to the TPP enzyme family
FSB73_RS17450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FSB73_RS17455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FSB73_RS17500	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FSB73_RS17505	COG1192	Involved in chromosome partitioning
FSB73_RS17510	COG1475	DNA binding
FSB73_RS17520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FSB73_RS17525	COG0277	FAD linked oxidase domain protein
FSB73_RS17540	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FSB73_RS17545	COG1388	LysM domain
FSB73_RS17545	COG1705	Flagellar rod assembly protein muramidase FlgJ
FSB73_RS17560	COG2153	protein acetylation
FSB73_RS17565	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FSB73_RS17570	COG0156	8-amino-7-oxononanoate synthase activity
FSB73_RS17580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSB73_RS17640	COG0488	(ABC) transporter
FSB73_RS17645	COG1584	GPR1 FUN34 yaaH family protein
FSB73_RS17650	COG0519	Catalyzes the synthesis of GMP from XMP
FSB73_RS17655	COG0363	glucosamine-6-phosphate deaminase activity
FSB73_RS17665	COG1595	DNA-templated transcription, initiation
FSB73_RS17675	COG0463	Glycosyl transferase, family 2
FSB73_RS17685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FSB73_RS17690	COG1104	cysteine desulfurase activity
FSB73_RS17710	COG0484	heat shock protein binding
FSB73_RS17720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FSB73_RS17735	COG4608	Belongs to the ABC transporter superfamily
FSB73_RS17745	COG4608	Belongs to the ABC transporter superfamily
FSB73_RS17755	COG0506	proline dehydrogenase activity
FSB73_RS17775	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FSB73_RS17790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSB73_RS17815	COG3668	Plasmid stabilization system
FSB73_RS17890	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS17895	COG2207	Transcriptional regulator
FSB73_RS17900	COG0494	nUDIX hydrolase
FSB73_RS17905	COG0693	protein deglycase activity
FSB73_RS17910	COG0589	response to stress
FSB73_RS17910	COG0475	glutathione-regulated potassium exporter activity
FSB73_RS17935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSB73_RS17955	COG1595	DNA-templated transcription, initiation
FSB73_RS17990	COG0588	phosphoglycerate mutase activity
FSB73_RS17995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FSB73_RS18005	COG0798	PFAM Bile acid sodium symporter
FSB73_RS18010	COG2226	methyltransferase
FSB73_RS18015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSB73_RS18050	COG2132	Multicopper oxidase
FSB73_RS18100	COG0640	Transcriptional regulator
FSB73_RS18110	COG2217	Heavy metal translocating P-type atpase
FSB73_RS18130	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FSB73_RS18170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSB73_RS18175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSB73_RS18240	COG4974	Belongs to the 'phage' integrase family
FSB73_RS18250	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSB73_RS18270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FSB73_RS18275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FSB73_RS18290	COG1472	Belongs to the glycosyl hydrolase 3 family
FSB73_RS18295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FSB73_RS18310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FSB73_RS18345	COG0492	ferredoxin-NADP+ reductase activity
FSB73_RS18355	COG2249	NAD(P)H dehydrogenase (quinone) activity
FSB73_RS18390	COG1640	4-alpha-glucanotransferase
FSB73_RS18395	COG1640	4-alpha-glucanotransferase
FSB73_RS18415	COG0626	cystathionine gamma-synthase activity
FSB73_RS18445	COG1363	Peptidase, m42
FSB73_RS18495	COG2346	COG2346, Truncated hemoglobins
FSB73_RS18535	COG0450	alkyl hydroperoxide reductase
FSB73_RS18545	COG0668	transmembrane transport
FSB73_RS18565	COG1410	methionine synthase
FSB73_RS18565	COG0646	methionine synthase
FSB73_RS18580	COG1410	methionine synthase
FSB73_RS18580	COG0646	methionine synthase
FSB73_RS18585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSB73_RS18650	COG2197	response regulator
FSB73_RS18670	COG1132	(ABC) transporter
FSB73_RS18685	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FSB73_RS18690	COG0247	lactate metabolic process
FSB73_RS18720	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FSB73_RS18725	COG0105	UTP biosynthetic process
FSB73_RS18730	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSB73_RS18750	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FSB73_RS18755	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FSB73_RS18765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSB73_RS18775	COG1862	Preprotein translocase
FSB73_RS18780	COG0237	dephospho-CoA kinase activity
FSB73_RS18805	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FSB73_RS18810	COG0363	glucosamine-6-phosphate deaminase activity
FSB73_RS18820	COG1053	succinate dehydrogenase
FSB73_RS18855	COG4974	Belongs to the 'phage' integrase family
FSB73_RS18860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FSB73_RS18885	COG0617	tRNA 3'-terminal CCA addition
FSB73_RS18900	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FSB73_RS18910	COG2733	membrane
FSB73_RS18915	COG2733	membrane
FSB73_RS18935	COG1309	transcriptional regulator
FSB73_RS18950	COG5000	phosphorelay sensor kinase activity
FSB73_RS18965	COG0252	asparaginase activity
FSB73_RS18985	COG3590	peptidase
FSB73_RS18990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSB73_RS18995	COG0825	malonyl-CoA metabolic process
FSB73_RS19030	COG4771	TonB-dependent receptor
FSB73_RS19040	COG3250	beta-galactosidase activity
FSB73_RS19070	COG0513	Belongs to the DEAD box helicase family
FSB73_RS19085	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FSB73_RS19105	COG4771	TonB-dependent receptor
FSB73_RS19110	COG2176	DNA-directed DNA polymerase activity
FSB73_RS19165	COG4555	ABC transporter
FSB73_RS19185	COG1309	transcriptional regulator
FSB73_RS19195	COG0675	Transposase, IS605 OrfB family
FSB73_RS19220	COG0018	arginyl-trna synthetase
FSB73_RS19225	COG0156	8-amino-7-oxononanoate synthase activity
FSB73_RS19235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSB73_RS19240	COG0242	peptide deformylase activity
FSB73_RS19250	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FSB73_RS19260	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FSB73_RS19270	COG1629	transport
FSB73_RS19320	COG1629	transport
FSB73_RS19325	COG4771	TonB-dependent receptor
FSB73_RS19410	COG0156	8-amino-7-oxononanoate synthase activity
FSB73_RS19415	COG0488	(ABC) transporter
FSB73_RS19420	COG0488	(ABC) transporter
FSB73_RS19435	COG4585	Histidine kinase
FSB73_RS19440	COG2885	chlorophyll binding
FSB73_RS19460	COG3250	beta-galactosidase activity
FSB73_RS19470	COG1570	exodeoxyribonuclease VII activity
FSB73_RS19535	COG0561	phosphatase activity
FSB73_RS19540	COG4771	TonB-dependent receptor
FSB73_RS19550	COG1917	Cupin 2, conserved barrel domain protein
FSB73_RS19550	COG4977	sequence-specific DNA binding
FSB73_RS19555	COG1408	metallophosphoesterase
FSB73_RS19560	COG3661	Belongs to the glycosyl hydrolase 67 family
FSB73_RS19565	COG3537	Alpha-1,2-mannosidase
FSB73_RS19590	COG4771	TonB-dependent receptor
FSB73_RS19600	COG1629	transport
FSB73_RS19615	COG0702	epimerase
FSB73_RS19635	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FSB73_RS19680	COG1609	Transcriptional regulator
FSB73_RS19740	COG1629	transport
FSB73_RS19820	COG4771	TonB-dependent receptor
FSB73_RS19855	COG0745	RESPONSE REGULATOR receiver
FSB73_RS19860	COG5002	protein histidine kinase activity
FSB73_RS19870	COG0793	Belongs to the peptidase S41A family
FSB73_RS19890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FSB73_RS19910	COG1131	(ABC) transporter
FSB73_RS19915	COG2223	nitrite transmembrane transporter activity
FSB73_RS19920	COG2186	Transcriptional regulator
FSB73_RS19930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FSB73_RS19960	COG3250	beta-galactosidase activity
FSB73_RS20000	COG1629	transport
FSB73_RS20000	COG4206	TonB-dependent receptor
FSB73_RS20070	COG0438	transferase activity, transferring glycosyl groups
FSB73_RS20100	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FSB73_RS20130	COG3685	Protein conserved in bacteria
FSB73_RS20150	COG2204	response regulator
FSB73_RS20165	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS20205	COG1629	transport
FSB73_RS20205	COG4206	TonB-dependent receptor
FSB73_RS20235	COG3119	arylsulfatase activity
FSB73_RS20260	COG3511	phospholipase C
FSB73_RS20290	COG4206	TonB-dependent receptor
FSB73_RS20290	COG1629	transport
FSB73_RS20350	COG0702	epimerase
FSB73_RS20445	COG1501	Belongs to the glycosyl hydrolase 31 family
FSB73_RS20460	COG3507	Belongs to the glycosyl hydrolase 43 family
FSB73_RS20465	COG3507	Belongs to the glycosyl hydrolase 43 family
FSB73_RS20465	COG2382	esterase
FSB73_RS20465	COG3693	PFAM glycoside hydrolase, family 10
FSB73_RS20505	COG4771	TonB-dependent receptor
FSB73_RS20510	COG4771	TonB-dependent receptor
FSB73_RS20585	COG3250	beta-galactosidase activity
FSB73_RS20610	COG1629	transport
FSB73_RS20655	COG0702	epimerase
FSB73_RS20660	COG1629	transport
FSB73_RS20675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FSB73_RS20680	COG2197	response regulator
FSB73_RS20810	COG2972	Histidine kinase
FSB73_RS20810	COG0745	RESPONSE REGULATOR receiver
FSB73_RS20815	COG3279	Response regulator of the LytR AlgR family
FSB73_RS20825	COG4948	Mandelate Racemase Muconate Lactonizing
FSB73_RS20860	COG0675	Transposase, IS605 OrfB family
FSB73_RS21040	COG2814	Major facilitator Superfamily
FSB73_RS21075	COG0708	Exodeoxyribonuclease III
FSB73_RS21110	COG3250	beta-galactosidase activity
FSB73_RS21150	COG1917	Cupin 2, conserved barrel domain protein
FSB73_RS21150	COG4977	sequence-specific DNA binding
FSB73_RS21160	COG3250	beta-galactosidase activity
FSB73_RS21185	COG0702	epimerase
FSB73_RS21195	COG4771	TonB-dependent receptor
FSB73_RS21205	COG4948	Mandelate Racemase Muconate Lactonizing
FSB73_RS21265	COG3420	alginic acid biosynthetic process
FSB73_RS21280	COG0673	inositol 2-dehydrogenase activity
FSB73_RS21295	COG3507	Belongs to the glycosyl hydrolase 43 family
FSB73_RS21305	COG2169	Transcriptional regulator
FSB73_RS21335	COG4206	TonB-dependent receptor
FSB73_RS21335	COG1629	transport
FSB73_RS21395	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FSB73_RS21395	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FSB73_RS21405	COG1028	Short-chain dehydrogenase reductase Sdr
FSB73_RS21470	COG3385	transposase activity
FSB73_RS21490	COG4974	Belongs to the 'phage' integrase family
FSB73_RS21510	COG4974	Belongs to the 'phage' integrase family
FSB73_RS21520	COG4974	Belongs to the 'phage' integrase family
FSB73_RS21535	COG0671	phosphoesterase, PA-phosphatase related
FSB73_RS21565	COG2194	sulfuric ester hydrolase activity
FSB73_RS21575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSB73_RS21580	COG0581	inorganic phosphate transmembrane transporter activity
FSB73_RS21590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FSB73_RS21650	COG1090	epimerase
FSB73_RS21810	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FSB73_RS21830	COG0489	protein tyrosine kinase activity
FSB73_RS21830	COG3206	protein involved in exopolysaccharide biosynthesis
FSB73_RS21865	COG0438	transferase activity, transferring glycosyl groups
FSB73_RS21865	COG0297	glycogen (starch) synthase activity
FSB73_RS21875	COG0175	sulfate reduction
FSB73_RS21880	COG0529	Catalyzes the synthesis of activated sulfate
FSB73_RS21890	COG0438	transferase activity, transferring glycosyl groups
FSB73_RS21910	COG0438	transferase activity, transferring glycosyl groups
FSB73_RS22050	COG0438	transferase activity, transferring glycosyl groups
FSB73_RS22160	COG3852	Histidine kinase
FSB73_RS22170	COG5002	protein histidine kinase activity
FSB73_RS22235	COG0745	RESPONSE REGULATOR receiver
FSB73_RS22240	COG2205	protein histidine kinase activity
FSB73_RS22255	COG3437	response regulator, receiver
FSB73_RS22260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FSB73_RS22305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FSB73_RS22360	COG0612	Peptidase, M16
FSB73_RS22365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FSB73_RS22375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FSB73_RS22385	COG4555	ABC transporter
FSB73_RS22395	COG0702	epimerase
FSB73_RS22400	COG4771	TonB-dependent receptor
FSB73_RS22430	COG0497	DNA recombination
FSB73_RS22440	COG3344	reverse transcriptase
FSB73_RS22530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS22535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS22555	COG4206	TonB-dependent receptor
FSB73_RS22555	COG1629	transport
FSB73_RS22570	COG1595	DNA-templated transcription, initiation
FSB73_RS22595	COG3254	rhamnose metabolic process
FSB73_RS22640	COG4948	Mandelate Racemase Muconate Lactonizing
FSB73_RS22655	COG0662	Cupin 2, conserved barrel domain protein
FSB73_RS22655	COG2207	Transcriptional regulator
FSB73_RS22685	COG0662	Cupin 2, conserved barrel domain protein
FSB73_RS22685	COG2207	Transcriptional regulator
FSB73_RS22700	COG0702	epimerase
FSB73_RS22705	COG4771	TonB-dependent receptor
FSB73_RS22720	COG2010	Cytochrome c
FSB73_RS22860	COG1629	transport
FSB73_RS22880	COG1629	transport
FSB73_RS22955	COG4771	TonB-dependent receptor
FSB73_RS23015	COG4942	peptidase
FSB73_RS23020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSB73_RS23080	COG4771	TonB-dependent receptor
FSB73_RS23085	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FSB73_RS23110	COG1629	transport
FSB73_RS23120	COG1629	transport
FSB73_RS23120	COG4206	TonB-dependent receptor