locus-tag	class	description
A9P82_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A9P82_RS00015	COG1917	Cupin 2, conserved barrel domain protein
A9P82_RS00015	COG4977	sequence-specific DNA binding
A9P82_RS00020	COG1764	response to oxidative stress
A9P82_RS00035	COG1160	GTP binding
A9P82_RS00050	COG0156	8-amino-7-oxononanoate synthase activity
A9P82_RS00055	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A9P82_RS00060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A9P82_RS00070	COG0025	NhaP-type Na H and K H
A9P82_RS00085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A9P82_RS00090	COG1809	phosphosulfolactate synthase activity
A9P82_RS00105	COG0594	ribonuclease P activity
A9P82_RS00115	COG0438	transferase activity, transferring glycosyl groups
A9P82_RS00130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9P82_RS00135	COG0501	Belongs to the peptidase M48B family
A9P82_RS00140	COG3682	Transcriptional regulator
A9P82_RS00180	COG3279	Response regulator of the LytR AlgR family
A9P82_RS00185	COG2972	Histidine kinase
A9P82_RS00195	COG0484	heat shock protein binding
A9P82_RS00215	COG0298	carbon dioxide binding
A9P82_RS00225	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A9P82_RS00230	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A9P82_RS00235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A9P82_RS00240	COG0375	protein maturation
A9P82_RS00315	COG0527	aspartate kinase activity
A9P82_RS00335	COG0544	peptidyl-prolyl cis-trans isomerase activity
A9P82_RS00345	COG0659	secondary active sulfate transmembrane transporter activity
A9P82_RS00395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9P82_RS00410	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A9P82_RS00435	COG1733	regulation of RNA biosynthetic process
A9P82_RS00460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A9P82_RS00485	COG2197	response regulator
A9P82_RS00520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A9P82_RS00525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A9P82_RS00530	COG2003	Belongs to the UPF0758 family
A9P82_RS00570	COG1368	sulfuric ester hydrolase activity
A9P82_RS00575	COG1605	Chorismate mutase
A9P82_RS00575	COG0077	Prephenate dehydratase
A9P82_RS00580	COG0436	Aminotransferase
A9P82_RS00595	COG0513	Belongs to the DEAD box helicase family
A9P82_RS00600	COG2877	3-deoxy-8-phosphooctulonate synthase activity
A9P82_RS00610	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A9P82_RS00615	COG1830	Aldolase
A9P82_RS00625	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A9P82_RS00635	COG0667	Aldo Keto reductase
A9P82_RS00680	COG4654	Cytochrome c, class I
A9P82_RS00695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A9P82_RS00710	COG0071	Belongs to the small heat shock protein (HSP20) family
A9P82_RS00715	COG2226	methyltransferase
A9P82_RS00735	COG0517	IMP dehydrogenase activity
A9P82_RS00735	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A9P82_RS00750	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A9P82_RS00765	COG1127	ABC transporter
A9P82_RS00775	COG0019	diaminopimelate decarboxylase activity
A9P82_RS00795	COG3340	Belongs to the peptidase S51 family
A9P82_RS00805	COG1702	phosphate starvation-inducible protein PhoH
A9P82_RS00820	COG0322	excinuclease ABC activity
A9P82_RS00825	COG5000	phosphorelay sensor kinase activity
A9P82_RS00830	COG3956	TIGRFAM MazG family protein
A9P82_RS00845	COG1309	transcriptional regulator
A9P82_RS00860	COG2814	Major facilitator Superfamily
A9P82_RS00870	COG2733	membrane
A9P82_RS00920	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A9P82_RS00920	COG0617	tRNA 3'-terminal CCA addition
A9P82_RS00920	COG0517	IMP dehydrogenase activity
A9P82_RS00950	COG1981	membrane
A9P82_RS00970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A9P82_RS00980	COG4206	TonB-dependent receptor
A9P82_RS00980	COG1629	transport
A9P82_RS00990	COG1349	DNA-binding transcription factor activity
A9P82_RS01000	COG1194	a g-specific adenine glycosylase
A9P82_RS01010	COG2910	NAD(P)H-binding
A9P82_RS01015	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A9P82_RS01035	COG4206	TonB-dependent receptor
A9P82_RS01035	COG1629	transport
A9P82_RS01045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS01070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS01080	COG1629	transport
A9P82_RS01105	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A9P82_RS01115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A9P82_RS01120	COG1166	arginine decarboxylase activity
A9P82_RS01125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A9P82_RS01140	COG1595	DNA-templated transcription, initiation
A9P82_RS01155	COG0506	proline dehydrogenase activity
A9P82_RS01165	COG1131	(ABC) transporter
A9P82_RS01205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9P82_RS01205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9P82_RS01210	COG1040	competence protein
A9P82_RS01220	COG0386	Belongs to the glutathione peroxidase family
A9P82_RS01280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A9P82_RS01305	COG3279	Response regulator of the LytR AlgR family
A9P82_RS01310	COG3275	phosphorelay sensor kinase activity
A9P82_RS01325	COG1053	succinate dehydrogenase
A9P82_RS01330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A9P82_RS01340	COG0668	transmembrane transport
A9P82_RS01360	COG0811	peptide transport
A9P82_RS01365	COG0848	biopolymer transport protein
A9P82_RS01380	COG0606	chelatase, subunit chli
A9P82_RS01390	COG0783	Belongs to the Dps family
A9P82_RS01395	COG1012	belongs to the aldehyde dehydrogenase family
A9P82_RS01410	COG0037	tRNA processing
A9P82_RS01420	COG0281	malic enzyme
A9P82_RS01420	COG0280	phosphate acetyltransferase
A9P82_RS01435	COG1611	Belongs to the LOG family
A9P82_RS01450	COG0494	nUDIX hydrolase
A9P82_RS01455	COG0668	transmembrane transport
A9P82_RS01470	COG1598	PFAM Uncharacterised protein family UPF0150
A9P82_RS01485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A9P82_RS01485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A9P82_RS01495	COG3047	cAMP biosynthetic process
A9P82_RS01510	COG1917	Cupin 2, conserved barrel domain protein
A9P82_RS01510	COG2207	Transcriptional regulator
A9P82_RS01515	COG0300	oxidoreductase activity
A9P82_RS01525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9P82_RS01530	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
A9P82_RS01540	COG1410	methionine synthase
A9P82_RS01540	COG0646	methionine synthase
A9P82_RS01555	COG3757	hydrolase, family 25
A9P82_RS01565	COG0191	fructose-bisphosphate aldolase activity
A9P82_RS01570	COG0586	Pfam SNARE associated Golgi protein
A9P82_RS01615	COG0438	transferase activity, transferring glycosyl groups
A9P82_RS01620	COG0438	transferase activity, transferring glycosyl groups
A9P82_RS01630	COG0552	protein localization to endoplasmic reticulum
A9P82_RS01635	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A9P82_RS01640	COG1051	belongs to the nudix hydrolase family
A9P82_RS01665	COG0450	alkyl hydroperoxide reductase
A9P82_RS01670	COG0564	pseudouridine synthase activity
A9P82_RS01675	COG1187	pseudouridine synthase activity
A9P82_RS01685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A9P82_RS01700	COG1528	Iron-storage protein
A9P82_RS01710	COG2169	Transcriptional regulator
A9P82_RS01715	COG4771	TonB-dependent receptor
A9P82_RS01730	COG0484	heat shock protein binding
A9P82_RS01735	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A9P82_RS01745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A9P82_RS01770	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
A9P82_RS01780	COG2814	Major facilitator Superfamily
A9P82_RS01800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9P82_RS01835	COG2270	Major facilitator Superfamily
A9P82_RS01840	COG1968	undecaprenyl-diphosphatase activity
A9P82_RS01845	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A9P82_RS01875	COG1741	Belongs to the pirin family
A9P82_RS01880	COG0443	Heat shock 70 kDa protein
A9P82_RS01885	COG0393	Putative heavy-metal-binding
A9P82_RS01890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A9P82_RS01900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9P82_RS01905	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A9P82_RS01910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A9P82_RS01915	COG0159	tryptophan synthase activity
A9P82_RS01925	COG0133	tryptophan synthase activity
A9P82_RS01935	COG0135	phosphoribosylanthranilate isomerase activity
A9P82_RS01940	COG0134	indole-3-glycerol-phosphate synthase activity
A9P82_RS01950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A9P82_RS01955	COG0512	Glutamine amidotransferase of anthranilate synthase
A9P82_RS01955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A9P82_RS01960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A9P82_RS01970	COG0738	Major facilitator superfamily
A9P82_RS01975	COG3254	rhamnose metabolic process
A9P82_RS01980	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS01995	COG0179	Fumarylacetoacetate (FAA) hydrolase
A9P82_RS02010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS02015	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9P82_RS02025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9P82_RS02030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9P82_RS02055	COG1629	transport
A9P82_RS02055	COG4206	TonB-dependent receptor
A9P82_RS02070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A9P82_RS02095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A9P82_RS02120	COG0864	Transcriptional regulator
A9P82_RS02155	COG1858	cytochrome C peroxidase
A9P82_RS02165	COG1472	Belongs to the glycosyl hydrolase 3 family
A9P82_RS02190	COG5002	protein histidine kinase activity
A9P82_RS02195	COG0745	RESPONSE REGULATOR receiver
A9P82_RS02205	COG2045	Belongs to the ComB family
A9P82_RS02225	COG0583	DNA-binding transcription factor activity
A9P82_RS02230	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9P82_RS02240	COG0667	Aldo Keto reductase
A9P82_RS02255	COG2267	carboxylic ester hydrolase activity
A9P82_RS02290	COG0359	binds to the 23S rRNA
A9P82_RS02295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A9P82_RS02300	COG0360	Binds together with S18 to 16S ribosomal RNA
A9P82_RS02305	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A9P82_RS02310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A9P82_RS02320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9P82_RS02325	COG2239	Acts as a magnesium transporter
A9P82_RS02335	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A9P82_RS02350	COG0668	transmembrane transport
A9P82_RS02360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9P82_RS02365	COG0628	permease
A9P82_RS02385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS02405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS02410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS02430	COG0793	Belongs to the peptidase S41A family
A9P82_RS02440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS02445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS02540	COG4152	abc transporter atp-binding protein
A9P82_RS02550	COG1253	flavin adenine dinucleotide binding
A9P82_RS02555	COG0254	rRNA binding
A9P82_RS02565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A9P82_RS02605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A9P82_RS02610	COG0628	permease
A9P82_RS02615	COG0596	Alpha beta hydrolase
A9P82_RS02615	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9P82_RS02625	COG1530	ribonuclease E activity
A9P82_RS02635	COG0776	regulation of translation
A9P82_RS02675	COG0166	Belongs to the GPI family
A9P82_RS02680	COG0590	tRNA wobble adenosine to inosine editing
A9P82_RS02685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A9P82_RS02690	COG3590	peptidase
A9P82_RS02705	COG0531	amino acid
A9P82_RS02715	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A9P82_RS02725	COG1252	NADH dehydrogenase
A9P82_RS02760	COG0363	glucosamine-6-phosphate deaminase activity
A9P82_RS02795	COG3537	Alpha-1,2-mannosidase
A9P82_RS02800	COG3345	alpha-galactosidase
A9P82_RS02820	COG4948	Mandelate Racemase Muconate Lactonizing
A9P82_RS02835	COG0702	epimerase
A9P82_RS02840	COG1629	transport
A9P82_RS02850	COG1725	Transcriptional regulator
A9P82_RS02855	COG3250	beta-galactosidase activity
A9P82_RS02875	COG1629	transport
A9P82_RS02885	COG1725	Transcriptional regulator
A9P82_RS02890	COG3250	beta-galactosidase activity
A9P82_RS02910	COG1629	transport
A9P82_RS02930	COG0009	L-threonylcarbamoyladenylate synthase
A9P82_RS02935	COG2171	N-acyltransferase activity
A9P82_RS02940	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A9P82_RS02960	COG1666	GTP binding
A9P82_RS02980	COG0424	maF-like protein
A9P82_RS02990	COG3655	Transcriptional regulator
A9P82_RS03005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A9P82_RS03010	COG2721	sulfolactate sulfo-lyase activity
A9P82_RS03015	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A9P82_RS03025	COG4221	oxidoreductase activity
A9P82_RS03035	COG0495	leucyl-tRNA aminoacylation
A9P82_RS03040	COG2177	Part of the ABC transporter FtsEX involved in
A9P82_RS03060	COG1199	ATP-dependent helicase activity
A9P82_RS03060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A9P82_RS03070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9P82_RS03075	COG1090	epimerase
A9P82_RS03105	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A9P82_RS03110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9P82_RS03110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9P82_RS03120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS03125	COG2877	3-deoxy-8-phosphooctulonate synthase activity
A9P82_RS03130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A9P82_RS03145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A9P82_RS03150	COG1490	D-aminoacyl-tRNA deacylase activity
A9P82_RS03155	COG1694	Mazg nucleotide pyrophosphohydrolase
A9P82_RS03165	COG1260	myo-inositol-1-phosphate synthase
A9P82_RS03170	COG1312	Catalyzes the dehydration of D-mannonate
A9P82_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS03180	COG0657	acetylesterase activity
A9P82_RS03180	COG2755	lipolytic protein G-D-S-L family
A9P82_RS03200	COG1904	glucuronate isomerase
A9P82_RS03210	COG1393	Belongs to the ArsC family
A9P82_RS03215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A9P82_RS03235	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A9P82_RS03240	COG1663	tetraacyldisaccharide 4'-kinase activity
A9P82_RS03245	COG0557	exoribonuclease II activity
A9P82_RS03255	COG1733	regulation of RNA biosynthetic process
A9P82_RS03260	COG0667	Aldo Keto reductase
A9P82_RS03270	COG2211	Major facilitator Superfamily
A9P82_RS03280	COG0514	ATP-dependent DNA helicase (RecQ)
A9P82_RS03285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A9P82_RS03290	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A9P82_RS03300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A9P82_RS03310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A9P82_RS03315	COG0813	purine-nucleoside phosphorylase activity
A9P82_RS03325	COG0758	DNA mediated transformation
A9P82_RS03355	COG2181	nitrate reductase activity
A9P82_RS03355	COG0247	lactate metabolic process
A9P82_RS03365	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A9P82_RS03405	COG2353	YceI-like domain
A9P82_RS03430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A9P82_RS03490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A9P82_RS03490	COG0519	Catalyzes the synthesis of GMP from XMP
A9P82_RS03495	COG1621	beta-fructofuranosidase activity
A9P82_RS03505	COG1309	transcriptional regulator
A9P82_RS03510	COG1132	(ABC) transporter
A9P82_RS03515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9P82_RS03530	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A9P82_RS03535	COG1446	asparaginase
A9P82_RS03540	COG3590	peptidase
A9P82_RS03550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A9P82_RS03570	COG0534	Mate efflux family protein
A9P82_RS03575	COG2890	protein-(glutamine-N5) methyltransferase activity
A9P82_RS03580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9P82_RS03585	COG0210	DNA helicase
A9P82_RS03590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A9P82_RS03610	COG1435	thymidine kinase activity
A9P82_RS03620	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A9P82_RS03630	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A9P82_RS03635	COG0247	lactate metabolic process
A9P82_RS03645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A9P82_RS03660	COG0482	sulfurtransferase activity
A9P82_RS03680	COG2267	carboxylic ester hydrolase activity
A9P82_RS03690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9P82_RS03695	COG0488	(ABC) transporter
A9P82_RS03710	COG0228	four-way junction DNA binding
A9P82_RS03715	COG0156	8-amino-7-oxononanoate synthase activity
A9P82_RS03720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A9P82_RS03730	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A9P82_RS03745	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS03755	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS03760	COG4221	oxidoreductase activity
A9P82_RS03765	COG4977	sequence-specific DNA binding
A9P82_RS03765	COG1917	Cupin 2, conserved barrel domain protein
A9P82_RS03775	COG1917	Cupin 2, conserved barrel domain protein
A9P82_RS03775	COG4977	sequence-specific DNA binding
A9P82_RS03780	COG0667	Aldo Keto reductase
A9P82_RS03785	COG0667	Aldo Keto reductase
A9P82_RS03790	COG0629	single-stranded DNA binding
A9P82_RS03820	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A9P82_RS03830	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A9P82_RS03850	COG1363	Peptidase, m42
A9P82_RS03865	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A9P82_RS03880	COG0539	negative regulation of cytoplasmic translation
A9P82_RS03905	COG0067	glutamate synthase
A9P82_RS03905	COG0069	glutamate synthase activity
A9P82_RS03905	COG0070	glutamate synthase
A9P82_RS03910	COG0791	NLP P60 protein
A9P82_RS03920	COG4206	TonB-dependent receptor
A9P82_RS03925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A9P82_RS03930	COG0540	Belongs to the ATCase OTCase family
A9P82_RS03935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A9P82_RS03945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A9P82_RS03955	COG0489	protein tyrosine kinase activity
A9P82_RS03980	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A9P82_RS03985	COG0167	dihydroorotate dehydrogenase activity
A9P82_RS03995	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A9P82_RS04000	COG0756	dUTP diphosphatase activity
A9P82_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS04040	COG1917	Cupin 2, conserved barrel domain protein
A9P82_RS04040	COG4977	sequence-specific DNA binding
A9P82_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS04050	COG1917	Cupin 2, conserved barrel domain protein
A9P82_RS04050	COG4977	sequence-specific DNA binding
A9P82_RS04065	COG0300	oxidoreductase activity
A9P82_RS04080	COG1733	regulation of RNA biosynthetic process
A9P82_RS04090	COG2814	Major facilitator Superfamily
A9P82_RS04105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A9P82_RS04105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A9P82_RS04110	COG1739	Uncharacterized protein family UPF0029
A9P82_RS04120	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
A9P82_RS04135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A9P82_RS04140	COG1301	dicarboxylic acid transport
A9P82_RS04145	COG0531	amino acid
A9P82_RS04170	COG0778	Nitroreductase
A9P82_RS04175	COG0194	GDP metabolic process
A9P82_RS04180	COG0601	transmembrane transport
A9P82_RS04225	COG0823	Involved in the tonB-independent uptake of proteins
A9P82_RS04225	COG1506	peptidase
A9P82_RS04235	COG2814	Major facilitator Superfamily
A9P82_RS04240	COG0667	Aldo Keto reductase
A9P82_RS04260	COG1289	transmembrane transporter activity
A9P82_RS04265	COG0193	aminoacyl-tRNA hydrolase activity
A9P82_RS04290	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A9P82_RS04295	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A9P82_RS04300	COG2003	Belongs to the UPF0758 family
A9P82_RS04320	COG3250	beta-galactosidase activity
A9P82_RS04340	COG0702	epimerase
A9P82_RS04345	COG4771	TonB-dependent receptor
A9P82_RS04350	COG2205	protein histidine kinase activity
A9P82_RS04350	COG0745	RESPONSE REGULATOR receiver
A9P82_RS04350	COG0745	RESPONSE REGULATOR receiver
A9P82_RS04350	COG3292	Two component regulator propeller
A9P82_RS04350	COG2205	protein histidine kinase activity
A9P82_RS04350	COG3292	Two component regulator propeller
A9P82_RS04365	COG1999	signal sequence binding
A9P82_RS04370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A9P82_RS04380	COG0525	valine-tRNA ligase activity
A9P82_RS04435	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A9P82_RS04440	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
A9P82_RS04440	COG0662	Cupin 2, conserved barrel domain protein
A9P82_RS04445	COG0667	Aldo Keto reductase
A9P82_RS04460	COG2255	four-way junction helicase activity
A9P82_RS04465	COG0436	Aminotransferase
A9P82_RS04470	COG0463	Glycosyl transferase, family 2
A9P82_RS04480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A9P82_RS04485	COG1914	H( )-stimulated, divalent metal cation uptake system
A9P82_RS04530	COG3279	Response regulator of the LytR AlgR family
A9P82_RS04535	COG3275	phosphorelay sensor kinase activity
A9P82_RS04540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A9P82_RS04550	COG2153	protein acetylation
A9P82_RS04555	COG4145	pantothenate transmembrane transporter activity
A9P82_RS04560	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A9P82_RS04570	COG1940	carbohydrate kinase activity
A9P82_RS04585	COG2095	MarC family integral membrane protein
A9P82_RS04595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A9P82_RS04600	COG0259	pyridoxamine-phosphate oxidase activity
A9P82_RS04615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A9P82_RS04630	COG3345	alpha-galactosidase
A9P82_RS04650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A9P82_RS04655	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A9P82_RS04660	COG4106	trans-aconitate 2-methyltransferase activity
A9P82_RS04670	COG0066	3-isopropylmalate dehydratase activity
A9P82_RS04680	COG1119	ATPase activity
A9P82_RS04705	COG0028	Belongs to the TPP enzyme family
A9P82_RS04710	COG0440	acetolactate synthase activity
A9P82_RS04720	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A9P82_RS04745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A9P82_RS04750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS04760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS04765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS04770	COG0793	Belongs to the peptidase S41A family
A9P82_RS04790	COG4206	TonB-dependent receptor
A9P82_RS04790	COG1629	transport
A9P82_RS04805	COG0165	Argininosuccinate lyase
A9P82_RS04810	COG3265	gluconokinase activity
A9P82_RS04820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A9P82_RS04825	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A9P82_RS04835	COG0778	Nitroreductase
A9P82_RS04840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A9P82_RS04845	COG1139	Iron-sulfur cluster binding protein
A9P82_RS04850	COG3609	addiction module antidote protein, CC2985 family
A9P82_RS04865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A9P82_RS04870	COG0107	imidazoleglycerol-phosphate synthase activity
A9P82_RS04875	COG0140	phosphoribosyl-ATP diphosphatase activity
A9P82_RS04875	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A9P82_RS04880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS04910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A9P82_RS04920	COG1381	Involved in DNA repair and RecF pathway recombination
A9P82_RS04935	COG1064	alcohol dehydrogenase
A9P82_RS04945	COG0717	Belongs to the dCTP deaminase family
A9P82_RS04965	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A9P82_RS04975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A9P82_RS04995	COG0612	Peptidase, M16
A9P82_RS05000	COG0038	chloride channel
A9P82_RS05005	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A9P82_RS05010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A9P82_RS05025	COG0148	phosphopyruvate hydratase activity
A9P82_RS05055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A9P82_RS05075	COG0405	Gamma-glutamyltransferase
A9P82_RS05085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A9P82_RS05090	COG2755	lipolytic protein G-D-S-L family
A9P82_RS05090	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
A9P82_RS05095	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A9P82_RS05100	COG0667	Aldo Keto reductase
A9P82_RS05105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A9P82_RS05105	COG0131	Imidazoleglycerol-phosphate dehydratase
A9P82_RS05110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A9P82_RS05115	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A9P82_RS05125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A9P82_RS05130	COG2239	Acts as a magnesium transporter
A9P82_RS05140	COG1331	Highly conserved protein containing a thioredoxin domain
A9P82_RS05145	COG1660	Displays ATPase and GTPase activities
A9P82_RS05150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A9P82_RS05170	COG0706	membrane insertase activity
A9P82_RS05185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A9P82_RS05195	COG1054	Belongs to the UPF0176 family
A9P82_RS05205	COG0306	phosphate transporter
A9P82_RS05210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A9P82_RS05215	COG0083	homoserine kinase activity
A9P82_RS05220	COG0577	efflux transmembrane transporter activity
A9P82_RS05225	COG0527	aspartate kinase activity
A9P82_RS05225	COG0460	homoserine dehydrogenase
A9P82_RS05230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9P82_RS05260	COG3279	Response regulator of the LytR AlgR family
A9P82_RS05265	COG3275	phosphorelay sensor kinase activity
A9P82_RS05275	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A9P82_RS05280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS05290	COG1131	(ABC) transporter
A9P82_RS05300	COG0668	transmembrane transport
A9P82_RS05310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A9P82_RS05315	COG1556	Lactate utilization protein
A9P82_RS05320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A9P82_RS05340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9P82_RS05345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS05365	COG3220	belongs to the UPF0276 family
A9P82_RS05380	COG0124	histidyl-tRNA synthetase
A9P82_RS05385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A9P82_RS05395	COG1695	Transcriptional regulator
A9P82_RS05400	COG1983	PspC domain protein
A9P82_RS05405	COG1546	Belongs to the CinA family
A9P82_RS05405	COG1058	Belongs to the CinA family
A9P82_RS05410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A9P82_RS05415	COG1418	mRNA catabolic process
A9P82_RS05420	COG0505	Belongs to the CarA family
A9P82_RS05455	COG2814	Major facilitator Superfamily
A9P82_RS05455	COG0477	Major facilitator Superfamily
A9P82_RS05495	COG0702	epimerase
A9P82_RS05500	COG1629	transport
A9P82_RS05505	COG1609	Transcriptional regulator
A9P82_RS05510	COG1609	Transcriptional regulator
A9P82_RS05515	COG3250	beta-galactosidase activity
A9P82_RS05530	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A9P82_RS05540	COG2989	Protein conserved in bacteria
A9P82_RS05550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A9P82_RS05560	COG3275	phosphorelay sensor kinase activity
A9P82_RS05565	COG3279	Response regulator of the LytR AlgR family
A9P82_RS05590	COG4206	TonB-dependent receptor
A9P82_RS05590	COG1629	transport
A9P82_RS05600	COG1595	DNA-templated transcription, initiation
A9P82_RS05610	COG0457	Tetratricopeptide repeat
A9P82_RS05615	COG2814	Major facilitator Superfamily
A9P82_RS05620	COG4948	Mandelate Racemase Muconate Lactonizing
A9P82_RS05635	COG0237	dephospho-CoA kinase activity
A9P82_RS05640	COG1862	Preprotein translocase
A9P82_RS05650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A9P82_RS05655	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9P82_RS05785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A9P82_RS05810	COG4585	Histidine kinase
A9P82_RS05845	COG4206	TonB-dependent receptor
A9P82_RS05845	COG1629	transport
A9P82_RS05915	COG1045	serine acetyltransferase
A9P82_RS05920	COG0297	glycogen (starch) synthase activity
A9P82_RS05955	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
A9P82_RS05965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A9P82_RS05970	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A9P82_RS06055	COG4771	TonB-dependent receptor
A9P82_RS06065	COG3292	Two component regulator propeller
A9P82_RS06065	COG0745	RESPONSE REGULATOR receiver
A9P82_RS06065	COG2205	protein histidine kinase activity
A9P82_RS06070	COG3292	Two component regulator propeller
A9P82_RS06070	COG0745	RESPONSE REGULATOR receiver
A9P82_RS06070	COG2205	protein histidine kinase activity
A9P82_RS06080	COG0105	UTP biosynthetic process
A9P82_RS06085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A9P82_RS06105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9P82_RS06110	COG1104	cysteine desulfurase activity
A9P82_RS06115	COG0450	alkyl hydroperoxide reductase
A9P82_RS06120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A9P82_RS06125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A9P82_RS06165	COG0489	protein tyrosine kinase activity
A9P82_RS06170	COG2166	iron-sulfur cluster assembly
A9P82_RS06175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A9P82_RS06195	COG0719	Fe-S assembly protein
A9P82_RS06200	COG0396	ATPase activity
A9P82_RS06205	COG4115	mRNA cleavage
A9P82_RS06215	COG0719	Fe-S assembly protein
A9P82_RS06220	COG0316	Belongs to the HesB IscA family
A9P82_RS06225	COG3158	transport of potassium into the cell
A9P82_RS06235	COG0047	phosphoribosylformylglycinamidine synthase activity
A9P82_RS06265	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A9P82_RS06270	COG0295	cytidine deaminase activity
A9P82_RS06275	COG0681	Belongs to the peptidase S26 family
A9P82_RS06280	COG0538	isocitrate dehydrogenase activity
A9P82_RS06295	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A9P82_RS06305	COG0488	(ABC) transporter
A9P82_RS06315	COG1765	OsmC-like protein
A9P82_RS06355	COG2027	D-alanyl-D-alanine carboxypeptidase
A9P82_RS06365	COG0321	lipoyl(octanoyl) transferase activity
A9P82_RS06365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A9P82_RS06370	COG1555	photosystem II stabilization
A9P82_RS06370	COG1596	polysaccharide export
A9P82_RS06375	COG0038	chloride channel
A9P82_RS06385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A9P82_RS06390	COG0589	response to stress
A9P82_RS06400	COG0148	phosphopyruvate hydratase activity
A9P82_RS06430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9P82_RS06450	COG0300	oxidoreductase activity
A9P82_RS06460	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A9P82_RS06480	COG0297	glycogen (starch) synthase activity
A9P82_RS06485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A9P82_RS06490	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9P82_RS06495	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9P82_RS06505	COG1131	(ABC) transporter
A9P82_RS06510	COG0702	epimerase
A9P82_RS06515	COG1629	transport
A9P82_RS06530	COG1678	Uncharacterized ACR, COG1678
A9P82_RS06535	COG1187	pseudouridine synthase activity
A9P82_RS06550	COG0006	proline dipeptidase activity
A9P82_RS06560	COG1183	phosphatidylcholine synthase activity
A9P82_RS06575	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A9P82_RS06580	COG0328	RNA-DNA hybrid ribonuclease activity
A9P82_RS06585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A9P82_RS06595	COG3275	phosphorelay sensor kinase activity
A9P82_RS06610	COG0805	protein transport
A9P82_RS06615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A9P82_RS06625	COG5002	protein histidine kinase activity
A9P82_RS06630	COG0745	RESPONSE REGULATOR receiver
A9P82_RS06655	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A9P82_RS06675	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
A9P82_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS06685	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A9P82_RS06695	COG4948	Mandelate Racemase Muconate Lactonizing
A9P82_RS06720	COG1428	Deoxynucleoside kinase
A9P82_RS06725	COG0180	Tryptophanyl-tRNA synthetase
A9P82_RS06745	COG0492	ferredoxin-NADP+ reductase activity
A9P82_RS06755	COG0049	tRNA binding
A9P82_RS06760	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A9P82_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS06795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A9P82_RS06810	COG0612	Peptidase, M16
A9P82_RS06830	COG1764	response to oxidative stress
A9P82_RS06835	COG0658	competence protein
A9P82_RS06835	COG2333	competence protein COMEC
A9P82_RS06840	COG0138	bifunctional purine biosynthesis protein purh
A9P82_RS06850	COG0517	IMP dehydrogenase activity
A9P82_RS06850	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A9P82_RS06860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A9P82_RS06865	COG0629	single-stranded DNA binding
A9P82_RS06880	COG1774	PSP1 C-terminal conserved region
A9P82_RS06885	COG0516	GMP reductase activity
A9P82_RS06885	COG0517	IMP dehydrogenase activity
A9P82_RS06915	COG4771	TonB-dependent receptor
A9P82_RS06925	COG0484	heat shock protein binding
A9P82_RS06930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A9P82_RS06935	COG0492	ferredoxin-NADP+ reductase activity
A9P82_RS06950	COG0423	glycine-tRNA ligase activity
A9P82_RS06980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A9P82_RS06985	COG0336	Belongs to the RNA methyltransferase TrmD family
A9P82_RS07000	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A9P82_RS07050	COG1132	(ABC) transporter
A9P82_RS07055	COG0463	Glycosyl transferase, family 2
A9P82_RS07090	COG4771	TonB-dependent receptor
A9P82_RS07115	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A9P82_RS07125	COG3250	beta-galactosidase activity
A9P82_RS07150	COG0702	epimerase
A9P82_RS07155	COG1629	transport
A9P82_RS07170	COG0702	epimerase
A9P82_RS07175	COG4771	TonB-dependent receptor
A9P82_RS07195	COG0006	proline dipeptidase activity
A9P82_RS07205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9P82_RS07215	COG0531	amino acid
A9P82_RS07220	COG3938	Belongs to the proline racemase family
A9P82_RS07225	COG1012	belongs to the aldehyde dehydrogenase family
A9P82_RS07230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A9P82_RS07285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A9P82_RS07290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A9P82_RS07295	COG1045	serine acetyltransferase
A9P82_RS07305	COG0512	Glutamine amidotransferase of anthranilate synthase
A9P82_RS07330	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9P82_RS07330	COG0022	dehydrogenase e1 component
A9P82_RS07340	COG0442	prolyl-tRNA aminoacylation
A9P82_RS07350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A9P82_RS07355	COG0825	malonyl-CoA metabolic process
A9P82_RS07375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A9P82_RS07380	COG3384	dioxygenase
A9P82_RS07390	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A9P82_RS07395	COG1619	proteins homologs of microcin C7 resistance protein MccF
A9P82_RS07400	COG1619	proteins homologs of microcin C7 resistance protein MccF
A9P82_RS07425	COG1649	PFAM Uncharacterised BCR, COG1649
A9P82_RS07445	COG0137	argininosuccinate synthase activity
A9P82_RS07450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A9P82_RS07485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A9P82_RS07490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A9P82_RS07505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A9P82_RS07510	COG0469	pyruvate kinase activity
A9P82_RS07515	COG0205	6-phosphofructokinase activity
A9P82_RS07525	COG1132	(ABC) transporter
A9P82_RS07535	COG1725	Transcriptional regulator
A9P82_RS07545	COG1131	(ABC) transporter
A9P82_RS07550	COG4221	oxidoreductase activity
A9P82_RS07555	COG0308	aminopeptidase N
A9P82_RS07575	COG1388	LysM domain
A9P82_RS07575	COG0741	lytic transglycosylase activity
A9P82_RS07580	COG0154	amidase activity
A9P82_RS07585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A9P82_RS07590	COG3239	Fatty acid desaturase
A9P82_RS07610	COG0514	ATP-dependent DNA helicase (RecQ)
A9P82_RS07625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A9P82_RS07640	COG0596	Alpha beta hydrolase
A9P82_RS07660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A9P82_RS07670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS07700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9P82_RS07710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A9P82_RS07735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A9P82_RS07750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS07765	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A9P82_RS07770	COG2264	protein methyltransferase activity
A9P82_RS07790	COG1136	(ABC) transporter
A9P82_RS07790	COG0577	efflux transmembrane transporter activity
A9P82_RS07815	COG3011	Protein conserved in bacteria
A9P82_RS07830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A9P82_RS07840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A9P82_RS07845	COG2017	converts alpha-aldose to the beta-anomer
A9P82_RS07850	COG0537	adenosine 5'-monophosphoramidase activity
A9P82_RS07855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A9P82_RS07860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS07875	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A9P82_RS07880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A9P82_RS07885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A9P82_RS07900	COG0085	RNA polymerase activity
A9P82_RS07930	COG0811	peptide transport
A9P82_RS07970	COG1629	transport
A9P82_RS07975	COG1472	Belongs to the glycosyl hydrolase 3 family
A9P82_RS07995	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9P82_RS08000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9P82_RS08060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A9P82_RS08065	COG0587	DNA-directed DNA polymerase activity
A9P82_RS08070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A9P82_RS08070	COG1199	ATP-dependent helicase activity
A9P82_RS08095	COG0335	large ribosomal subunit rRNA binding
A9P82_RS08100	COG1271	oxidase subunit
A9P82_RS08130	COG1131	(ABC) transporter
A9P82_RS08140	COG0527	aspartate kinase activity
A9P82_RS08150	COG2885	chlorophyll binding
A9P82_RS08150	COG3047	cAMP biosynthetic process
A9P82_RS08175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A9P82_RS08175	COG1796	DNA polymerase
A9P82_RS08185	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A9P82_RS08190	COG4974	Belongs to the 'phage' integrase family
A9P82_RS08195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A9P82_RS08205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A9P82_RS08215	COG3279	Response regulator of the LytR AlgR family
A9P82_RS08220	COG3275	phosphorelay sensor kinase activity
A9P82_RS08250	COG3258	Cytochrome c
A9P82_RS08265	COG3279	Response regulator of the LytR AlgR family
A9P82_RS08270	COG3275	phosphorelay sensor kinase activity
A9P82_RS08275	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A9P82_RS08280	COG1674	ftsk spoiiie
A9P82_RS08285	COG0793	Belongs to the peptidase S41A family
A9P82_RS08615	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
A9P82_RS08620	COG0251	oxidation-reduction process
A9P82_RS08630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A9P82_RS08645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A9P82_RS08660	COG1733	regulation of RNA biosynthetic process
A9P82_RS08665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A9P82_RS08670	COG0563	adenylate kinase activity
A9P82_RS08690	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A9P82_RS08695	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A9P82_RS08715	COG2096	Adenosyltransferase
A9P82_RS08720	COG1136	(ABC) transporter
A9P82_RS08725	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A9P82_RS08730	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A9P82_RS08825	COG4771	TonB-dependent receptor
A9P82_RS08875	COG0358	DNA primase activity
A9P82_RS08900	COG0724	RNA recognition motif
A9P82_RS08905	COG1278	Cold shock
A9P82_RS08920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A9P82_RS08925	COG2059	Chromate
A9P82_RS08945	COG2204	response regulator
A9P82_RS08950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A9P82_RS08960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A9P82_RS09000	COG0181	hydroxymethylbilane synthase activity
A9P82_RS09005	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A9P82_RS09030	COG0667	Aldo Keto reductase
A9P82_RS09040	COG5002	protein histidine kinase activity
A9P82_RS09045	COG0745	RESPONSE REGULATOR receiver
A9P82_RS09065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9P82_RS09065	COG0072	phenylalanine-tRNA ligase activity
A9P82_RS09080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A9P82_RS09090	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
A9P82_RS09095	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A9P82_RS09105	COG1418	mRNA catabolic process
A9P82_RS09110	COG1136	(ABC) transporter
A9P82_RS09110	COG0577	efflux transmembrane transporter activity
A9P82_RS09115	COG0577	efflux transmembrane transporter activity
A9P82_RS09120	COG1136	(ABC) transporter
A9P82_RS09120	COG0577	efflux transmembrane transporter activity
A9P82_RS09130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A9P82_RS09135	COG0688	phosphatidylethanolamine metabolic process
A9P82_RS09140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A9P82_RS09145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A9P82_RS09150	COG0402	S-adenosylhomocysteine deaminase activity
A9P82_RS09160	COG0724	RNA recognition motif
A9P82_RS09170	COG0300	oxidoreductase activity
A9P82_RS09190	COG2186	Transcriptional regulator
A9P82_RS09195	COG2133	pyrroloquinoline quinone binding
A9P82_RS09200	COG2321	neutral zinc metallopeptidase
A9P82_RS09205	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A9P82_RS09225	COG1408	metallophosphoesterase
A9P82_RS09230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A9P82_RS09235	COG1192	Involved in chromosome partitioning
A9P82_RS09240	COG1475	DNA binding
A9P82_RS09250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A9P82_RS09255	COG0277	FAD linked oxidase domain protein
A9P82_RS09295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A9P82_RS09310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9P82_RS09330	COG1940	carbohydrate kinase activity
A9P82_RS09340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9P82_RS09355	COG1705	Flagellar rod assembly protein muramidase FlgJ
A9P82_RS09360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A9P82_RS09365	COG0793	Belongs to the peptidase S41A family
A9P82_RS09370	COG0175	sulfate reduction
A9P82_RS09375	COG0175	sulfate reduction
A9P82_RS09385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A9P82_RS09385	COG1648	precorrin-2 dehydrogenase activity
A9P82_RS09390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A9P82_RS09400	COG0730	response to heat
A9P82_RS09405	COG0343	queuine tRNA-ribosyltransferase activity
A9P82_RS09415	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A9P82_RS09430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A9P82_RS09435	COG0509	glycine decarboxylation via glycine cleavage system
A9P82_RS09450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9P82_RS09470	COG2329	Antibiotic biosynthesis monooxygenase
A9P82_RS09485	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A9P82_RS09490	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9P82_RS09495	COG1733	regulation of RNA biosynthetic process
A9P82_RS09505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A9P82_RS09510	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A9P82_RS09515	COG0195	Participates in both transcription termination and antitermination
A9P82_RS09520	COG0779	Required for maturation of 30S ribosomal subunits
A9P82_RS09530	COG1138	Cytochrome C-type biogenesis protein
A9P82_RS09540	COG0463	Glycosyl transferase, family 2
A9P82_RS09550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A9P82_RS09575	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A9P82_RS09595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A9P82_RS09600	COG0673	inositol 2-dehydrogenase activity
A9P82_RS09605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A9P82_RS09630	COG0824	Thioesterase
A9P82_RS09640	COG1309	transcriptional regulator
A9P82_RS09650	COG1428	Deoxynucleoside kinase
A9P82_RS09680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A9P82_RS09690	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
A9P82_RS09690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A9P82_RS09695	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A9P82_RS09700	COG1078	dGTPase activity
A9P82_RS09705	COG0714	Associated with various cellular activities
A9P82_RS09725	COG0798	PFAM Bile acid sodium symporter
A9P82_RS09730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A9P82_RS09735	COG0640	Transcriptional regulator
A9P82_RS09740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A9P82_RS09755	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9P82_RS09760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A9P82_RS09780	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A9P82_RS09785	COG1234	tRNA 3'-trailer cleavage
A9P82_RS09810	COG3104	oligopeptide transport
A9P82_RS09815	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A9P82_RS09820	COG0439	Biotin carboxylase
A9P82_RS09830	COG0511	ligase activity, forming carbon-carbon bonds
A9P82_RS09840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A9P82_RS09855	COG0792	nuclease activity
A9P82_RS09860	COG0583	DNA-binding transcription factor activity
A9P82_RS09865	COG2855	membrane
A9P82_RS09885	COG4974	Belongs to the 'phage' integrase family
A9P82_RS09895	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9P82_RS09900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A9P82_RS09905	COG1011	Hydrolase
A9P82_RS09920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A9P82_RS09925	COG1132	(ABC) transporter
A9P82_RS09945	COG0196	riboflavin kinase activity
A9P82_RS09955	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A9P82_RS09960	COG0297	glycogen (starch) synthase activity
A9P82_RS09970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A9P82_RS09980	COG2272	Belongs to the type-B carboxylesterase lipase family
A9P82_RS09985	COG5002	protein histidine kinase activity
A9P82_RS09990	COG0745	RESPONSE REGULATOR receiver
A9P82_RS10000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A9P82_RS10020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9P82_RS10025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9P82_RS10030	COG0542	response to heat
A9P82_RS10050	COG1629	transport
A9P82_RS10070	COG1917	Cupin 2, conserved barrel domain protein
A9P82_RS10070	COG4977	sequence-specific DNA binding
A9P82_RS10075	COG4221	oxidoreductase activity
A9P82_RS10085	COG0612	Peptidase, M16
A9P82_RS10090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9P82_RS10095	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9P82_RS10110	COG0702	epimerase
A9P82_RS10115	COG4771	TonB-dependent receptor
A9P82_RS10140	COG4771	TonB-dependent receptor
A9P82_RS10160	COG3250	beta-galactosidase activity
A9P82_RS10180	COG1690	Belongs to the RtcB family
A9P82_RS10190	COG3537	Alpha-1,2-mannosidase
A9P82_RS10210	COG0561	phosphatase activity
A9P82_RS10215	COG4771	TonB-dependent receptor
A9P82_RS10235	COG3408	Glycogen debranching enzyme
A9P82_RS10235	COG3119	arylsulfatase activity
A9P82_RS10260	COG0738	Major facilitator superfamily
A9P82_RS10270	COG3537	Alpha-1,2-mannosidase
A9P82_RS10285	COG1629	transport
A9P82_RS10290	COG0702	epimerase
A9P82_RS10315	COG3940	Belongs to the glycosyl hydrolase 43 family
A9P82_RS10325	COG3537	Alpha-1,2-mannosidase
A9P82_RS10330	COG3537	Alpha-1,2-mannosidase
A9P82_RS10365	COG4952	isomerase
A9P82_RS10370	COG3254	rhamnose metabolic process
A9P82_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS10375	COG3347	Dehydrogenase
A9P82_RS10395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS10400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS10415	COG1629	transport
A9P82_RS10415	COG4206	TonB-dependent receptor
A9P82_RS10435	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
A9P82_RS10440	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS10460	COG3590	peptidase
A9P82_RS10470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9P82_RS10500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A9P82_RS10505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A9P82_RS10510	COG0084	hydrolase, TatD family'
A9P82_RS10525	COG0210	DNA helicase
A9P82_RS10570	COG1629	transport
A9P82_RS10570	COG4206	TonB-dependent receptor
A9P82_RS10575	COG4974	Belongs to the 'phage' integrase family
A9P82_RS10600	COG3177	Filamentation induced by cAMP protein fic
A9P82_RS10655	COG3081	Nucleoid-associated protein
A9P82_RS10690	COG2235	arginine
A9P82_RS10725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A9P82_RS10730	COG2363	Small membrane protein
A9P82_RS10735	COG0358	DNA primase activity
A9P82_RS10740	COG0802	atpase or kinase
A9P82_RS10755	COG0673	inositol 2-dehydrogenase activity
A9P82_RS10765	COG0673	inositol 2-dehydrogenase activity
A9P82_RS10775	COG2211	Major facilitator Superfamily
A9P82_RS10780	COG1082	Xylose isomerase domain protein TIM barrel
A9P82_RS10790	COG2217	Heavy metal translocating P-type atpase
A9P82_RS10795	COG0017	Asparaginyl-tRNA synthetase
A9P82_RS10800	COG1309	transcriptional regulator
A9P82_RS10815	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A9P82_RS10850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A9P82_RS10850	COG0551	DNA topoisomerase type I activity
A9P82_RS10885	COG2814	Major facilitator Superfamily
A9P82_RS10915	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A9P82_RS10930	COG0024	Methionine aminopeptidase
A9P82_RS10945	COG1309	transcriptional regulator
A9P82_RS10950	COG2814	Major facilitator Superfamily
A9P82_RS10960	COG1733	regulation of RNA biosynthetic process
A9P82_RS11045	COG4977	sequence-specific DNA binding
A9P82_RS11045	COG1917	Cupin 2, conserved barrel domain protein
A9P82_RS11050	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS11075	COG1733	regulation of RNA biosynthetic process
A9P82_RS11275	COG0629	single-stranded DNA binding
A9P82_RS11290	COG1011	Hydrolase
A9P82_RS11300	COG1609	Transcriptional regulator
A9P82_RS11310	COG2884	Cell division ATP-binding protein ftsE
A9P82_RS11325	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A9P82_RS11330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A9P82_RS11350	COG0784	Response regulator, receiver
A9P82_RS11350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9P82_RS11350	COG2198	Histidine kinase
A9P82_RS11350	COG2205	protein histidine kinase activity
A9P82_RS11365	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A9P82_RS11375	COG0058	SHG alpha-glucan phosphorylase activity
A9P82_RS11380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A9P82_RS11390	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A9P82_RS11435	COG1629	transport
A9P82_RS11435	COG4206	TonB-dependent receptor
A9P82_RS11440	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A9P82_RS11455	COG0366	Alpha amylase catalytic
A9P82_RS11490	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A9P82_RS11495	COG2315	Protein conserved in bacteria
A9P82_RS11520	COG2153	protein acetylation
A9P82_RS11525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A9P82_RS11530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A9P82_RS11535	COG0571	ribonuclease III activity
A9P82_RS11540	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A9P82_RS11565	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A9P82_RS11590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A9P82_RS11595	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A9P82_RS11600	COG0300	oxidoreductase activity
A9P82_RS11610	COG3852	Histidine kinase
A9P82_RS11620	COG3177	Filamentation induced by cAMP protein fic
A9P82_RS11625	COG1136	(ABC) transporter
A9P82_RS11640	COG0577	efflux transmembrane transporter activity
A9P82_RS11645	COG1136	(ABC) transporter
A9P82_RS11675	COG1136	(ABC) transporter
A9P82_RS11675	COG0577	efflux transmembrane transporter activity
A9P82_RS11680	COG0577	efflux transmembrane transporter activity
A9P82_RS11685	COG1136	(ABC) transporter
A9P82_RS11685	COG0577	efflux transmembrane transporter activity
A9P82_RS11700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A9P82_RS11740	COG4771	TonB-dependent receptor
A9P82_RS11745	COG1629	transport
A9P82_RS11745	COG4206	TonB-dependent receptor
A9P82_RS11760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A9P82_RS11765	COG1970	mechanosensitive ion channel activity
A9P82_RS11770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A9P82_RS11785	COG0772	Belongs to the SEDS family
A9P82_RS11790	COG0768	penicillin binding
A9P82_RS11800	COG1792	Involved in formation and maintenance of cell shape
A9P82_RS11805	COG1077	Cell shape determining protein MreB Mrl
A9P82_RS11830	COG0233	cytoplasmic translational termination
A9P82_RS11835	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A9P82_RS11840	COG1162	GTPase activity
A9P82_RS11855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A9P82_RS11875	COG4771	TonB-dependent receptor
A9P82_RS11895	COG1597	lipid kinase activity
A9P82_RS11905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A9P82_RS11915	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A9P82_RS11920	COG0445	tRNA wobble uridine modification
A9P82_RS11930	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A9P82_RS11935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A9P82_RS11940	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A9P82_RS11960	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A9P82_RS11980	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A9P82_RS11995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A9P82_RS12000	COG3387	PFAM Glycoside hydrolase 15-related
A9P82_RS12005	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A9P82_RS12010	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A9P82_RS12015	COG3279	Response regulator of the LytR AlgR family
A9P82_RS12030	COG3275	phosphorelay sensor kinase activity
A9P82_RS12070	COG0151	Belongs to the GarS family
A9P82_RS12090	COG3275	phosphorelay sensor kinase activity
A9P82_RS12135	COG3250	beta-galactosidase activity
A9P82_RS12150	COG1472	Belongs to the glycosyl hydrolase 3 family
A9P82_RS12155	COG2755	lipolytic protein G-D-S-L family
A9P82_RS12155	COG0657	acetylesterase activity
A9P82_RS12165	COG1629	transport
A9P82_RS12170	COG0702	epimerase
A9P82_RS12180	COG1501	Belongs to the glycosyl hydrolase 31 family
A9P82_RS12190	COG1472	Belongs to the glycosyl hydrolase 3 family
A9P82_RS12200	COG3250	beta-galactosidase activity
A9P82_RS12215	COG3250	beta-galactosidase activity
A9P82_RS12240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A9P82_RS12245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A9P82_RS12250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A9P82_RS12270	COG2706	6-phosphogluconolactonase activity
A9P82_RS12280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A9P82_RS12280	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A9P82_RS12285	COG1388	LysM domain
A9P82_RS12285	COG4932	domain protein
A9P82_RS12290	COG0004	ammonium transporteR
A9P82_RS12295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A9P82_RS12310	COG1136	(ABC) transporter
A9P82_RS12330	COG0577	efflux transmembrane transporter activity
A9P82_RS12350	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
A9P82_RS12360	COG0302	gtp cyclohydrolase
A9P82_RS12370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A9P82_RS12380	COG1607	acyl-coa hydrolase
A9P82_RS12390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A9P82_RS12395	COG0081	regulation of translation
A9P82_RS12400	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A9P82_RS12405	COG0222	ribosome binding
A9P82_RS12410	COG3142	Participates in the control of copper homeostasis
A9P82_RS12430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9P82_RS12450	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A9P82_RS12475	COG0750	zinc metalloprotease
A9P82_RS12480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A9P82_RS12515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A9P82_RS12525	COG1629	transport
A9P82_RS12540	COG2353	YceI-like domain
A9P82_RS12555	COG0592	DNA-directed DNA polymerase activity
A9P82_RS12565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A9P82_RS12570	COG0326	Molecular chaperone. Has ATPase activity
A9P82_RS12575	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A9P82_RS12580	COG0149	triose-phosphate isomerase activity
A9P82_RS12600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A9P82_RS12605	COG1760	l-serine dehydratase
A9P82_RS12615	COG0436	Aminotransferase
A9P82_RS12620	COG3537	Alpha-1,2-mannosidase
A9P82_RS12635	COG3940	Belongs to the glycosyl hydrolase 43 family
A9P82_RS12650	COG0561	phosphatase activity
A9P82_RS12655	COG4771	TonB-dependent receptor
A9P82_RS12680	COG0738	Major facilitator superfamily
A9P82_RS12700	COG0702	epimerase
A9P82_RS12705	COG4771	TonB-dependent receptor
A9P82_RS12735	COG1629	transport
A9P82_RS12760	COG1629	transport
A9P82_RS12760	COG4206	TonB-dependent receptor
A9P82_RS12770	COG3537	Alpha-1,2-mannosidase
A9P82_RS12780	COG3537	Alpha-1,2-mannosidase
A9P82_RS12795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A9P82_RS12815	COG4977	sequence-specific DNA binding
A9P82_RS12815	COG1917	Cupin 2, conserved barrel domain protein
A9P82_RS12850	COG2132	Multicopper oxidase
A9P82_RS12870	COG3781	membrane
A9P82_RS12875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A9P82_RS12875	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A9P82_RS12880	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
A9P82_RS12890	COG0579	oxidoreductase
A9P82_RS13045	COG0702	epimerase
A9P82_RS13080	COG3525	Glycosyl hydrolase, family 20, catalytic domain
A9P82_RS13085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A9P82_RS13135	COG4771	TonB-dependent receptor
A9P82_RS13140	COG1940	carbohydrate kinase activity
A9P82_RS13155	COG4771	TonB-dependent receptor
A9P82_RS13160	COG0702	epimerase
A9P82_RS13180	COG1472	Belongs to the glycosyl hydrolase 3 family
A9P82_RS13190	COG1012	belongs to the aldehyde dehydrogenase family
A9P82_RS13210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A9P82_RS13215	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
A9P82_RS13225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A9P82_RS13245	COG3537	Alpha-1,2-mannosidase
A9P82_RS13255	COG1696	Membrane protein involved in D-alanine export
A9P82_RS13260	COG1217	gtp-binding protein TYPA
A9P82_RS13265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A9P82_RS13270	COG0009	L-threonylcarbamoyladenylate synthase
A9P82_RS13280	COG1305	Transglutaminase-like
A9P82_RS13290	COG2308	Evidence 4 Homologs of previously reported genes of
A9P82_RS13295	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A9P82_RS13300	COG0519	Catalyzes the synthesis of GMP from XMP
A9P82_RS13310	COG0632	four-way junction helicase activity
A9P82_RS13320	COG1902	pentaerythritol trinitrate reductase activity
A9P82_RS13325	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A9P82_RS13330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A9P82_RS13335	COG0649	NAD binding
A9P82_RS13350	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
A9P82_RS13370	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A9P82_RS13380	COG1034	ATP synthesis coupled electron transport
A9P82_RS13385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A9P82_RS13400	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A9P82_RS13410	COG0713	ATP synthesis coupled electron transport
A9P82_RS13415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A9P82_RS13420	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A9P82_RS13425	COG1007	ATP synthesis coupled electron transport
A9P82_RS13430	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A9P82_RS13435	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A9P82_RS13445	COG0113	porphobilinogen synthase activity
A9P82_RS13455	COG0408	coproporphyrinogen oxidase activity
A9P82_RS13460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A9P82_RS13465	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A9P82_RS13475	COG0126	phosphoglycerate kinase activity
A9P82_RS13495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9P82_RS13495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9P82_RS13505	COG1214	PFAM Peptidase M22, glycoprotease
A9P82_RS13510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A9P82_RS13520	COG0437	4 iron, 4 sulfur cluster binding
A9P82_RS13545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A9P82_RS13550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A9P82_RS13555	COG0109	protoheme IX farnesyltransferase activity
A9P82_RS13565	COG1845	cytochrome c oxidase, subunit III
A9P82_RS13575	COG2361	Protein of unknown function DUF86
A9P82_RS13600	COG2030	dehydratase
A9P82_RS13605	COG1960	acyl-CoA dehydrogenase activity
A9P82_RS13645	COG2197	response regulator
A9P82_RS13660	COG2322	membrane
A9P82_RS13675	COG4771	TonB-dependent receptor
A9P82_RS13680	COG0702	epimerase
A9P82_RS13695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS13705	COG4206	TonB-dependent receptor
A9P82_RS13705	COG1629	transport
A9P82_RS13720	COG3275	phosphorelay sensor kinase activity
A9P82_RS13725	COG3279	Response regulator of the LytR AlgR family
A9P82_RS13735	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
A9P82_RS13740	COG1629	transport
A9P82_RS13745	COG0561	phosphatase activity
A9P82_RS13755	COG4124	Belongs to the glycosyl hydrolase 26 family
A9P82_RS13770	COG1472	Belongs to the glycosyl hydrolase 3 family
A9P82_RS13775	COG1137	ATPase activity
A9P82_RS13800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A9P82_RS13820	COG0581	inorganic phosphate transmembrane transporter activity
A9P82_RS13825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A9P82_RS13835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A9P82_RS13840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A9P82_RS13845	COG0052	Belongs to the universal ribosomal protein uS2 family
A9P82_RS13850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A9P82_RS13880	COG3511	phospholipase C
A9P82_RS13885	COG0602	queuosine metabolic process
A9P82_RS13890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A9P82_RS13900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9P82_RS13910	COG1538	Outer membrane efflux protein
A9P82_RS13930	COG0018	arginyl-trna synthetase
A9P82_RS13940	COG0523	cobalamin synthesis protein
A9P82_RS13960	COG0321	lipoyl(octanoyl) transferase activity
A9P82_RS13965	COG3177	Filamentation induced by cAMP protein fic
A9P82_RS13995	COG0556	nucleotide-excision repair
A9P82_RS14005	COG4191	Histidine kinase
A9P82_RS14015	COG0010	Belongs to the arginase family
A9P82_RS14025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A9P82_RS14030	COG3958	Transketolase
A9P82_RS14055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A9P82_RS14060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A9P82_RS14065	COG4771	TonB-dependent receptor
A9P82_RS14075	COG2304	oxidoreductase activity
A9P82_RS14085	COG1028	Short-chain dehydrogenase reductase Sdr
A9P82_RS14110	COG0784	Response regulator, receiver
A9P82_RS14110	COG2205	protein histidine kinase activity
A9P82_RS14125	COG0573	inorganic phosphate transmembrane transporter activity
A9P82_RS14135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A9P82_RS14140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A9P82_RS14155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A9P82_RS14160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A9P82_RS14165	COG0772	Belongs to the SEDS family
A9P82_RS14170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A9P82_RS14175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A9P82_RS14180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A9P82_RS14185	COG0768	penicillin binding
A9P82_RS14195	COG0275	rRNA processing
A9P82_RS14200	COG2001	Belongs to the MraZ family
A9P82_RS14210	COG1193	negative regulation of DNA recombination
A9P82_RS14250	COG1082	Xylose isomerase domain protein TIM barrel
A9P82_RS14255	COG4948	Mandelate Racemase Muconate Lactonizing
A9P82_RS14260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A9P82_RS14265	COG1959	2 iron, 2 sulfur cluster binding
A9P82_RS14270	COG0460	homoserine dehydrogenase
A9P82_RS14280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A9P82_RS14285	COG2885	chlorophyll binding
A9P82_RS14305	COG1610	YqeY-like protein
A9P82_RS14320	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A9P82_RS14345	COG3279	Response regulator of the LytR AlgR family
A9P82_RS14350	COG3275	phosphorelay sensor kinase activity
A9P82_RS14360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A9P82_RS14360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A9P82_RS14370	COG1047	Peptidyl-prolyl cis-trans
A9P82_RS14375	COG3876	Protein conserved in bacteria
A9P82_RS14380	COG0564	pseudouridine synthase activity
A9P82_RS14385	COG0504	CTP synthase activity
A9P82_RS14400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A9P82_RS14405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A9P82_RS14410	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A9P82_RS14415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A9P82_RS14420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A9P82_RS14425	COG0202	RNA polymerase activity
A9P82_RS14430	COG0203	ribosomal protein L17
A9P82_RS14440	COG3292	Two component regulator propeller
A9P82_RS14440	COG0745	RESPONSE REGULATOR receiver
A9P82_RS14440	COG2205	protein histidine kinase activity
A9P82_RS14440	COG0745	RESPONSE REGULATOR receiver
A9P82_RS14440	COG3292	Two component regulator propeller
A9P82_RS14440	COG2205	protein histidine kinase activity
A9P82_RS14450	COG4771	TonB-dependent receptor
A9P82_RS14480	COG3250	beta-galactosidase activity
A9P82_RS14500	COG1522	sequence-specific DNA binding
A9P82_RS14510	COG0492	ferredoxin-NADP+ reductase activity
A9P82_RS14530	COG1629	transport
A9P82_RS14535	COG0702	epimerase
A9P82_RS14540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS14545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS14555	COG0051	transcription antitermination factor activity, RNA binding
A9P82_RS14560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A9P82_RS14565	COG0088	Forms part of the polypeptide exit tunnel
A9P82_RS14570	COG0089	rRNA binding
A9P82_RS14575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A9P82_RS14580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A9P82_RS14590	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A9P82_RS14595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A9P82_RS14600	COG0255	Belongs to the universal ribosomal protein uL29 family
A9P82_RS14605	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A9P82_RS14610	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A9P82_RS14615	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A9P82_RS14620	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A9P82_RS14625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A9P82_RS14630	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A9P82_RS14635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A9P82_RS14640	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A9P82_RS14645	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A9P82_RS14650	COG1841	ribosomal large subunit assembly
A9P82_RS14655	COG0200	Binds to the 23S rRNA
A9P82_RS14660	COG0201	protein transport
A9P82_RS14665	COG1472	Belongs to the glycosyl hydrolase 3 family
A9P82_RS14670	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A9P82_RS14675	COG1984	allophanate hydrolase subunit 2
A9P82_RS14685	COG1914	H( )-stimulated, divalent metal cation uptake system
A9P82_RS14695	COG2081	HI0933 family
A9P82_RS14700	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A9P82_RS14705	COG3657	addiction module killer protein
A9P82_RS14715	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A9P82_RS14725	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A9P82_RS14740	COG0604	alcohol dehydrogenase
A9P82_RS14770	COG2207	Transcriptional regulator
A9P82_RS14770	COG0662	Cupin 2, conserved barrel domain protein
A9P82_RS14795	COG4974	Belongs to the 'phage' integrase family
A9P82_RS14810	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A9P82_RS14815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9P82_RS14815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9P82_RS14830	COG3408	Glycogen debranching enzyme
A9P82_RS14845	COG0045	succinate-CoA ligase (ADP-forming) activity
A9P82_RS14855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A9P82_RS14860	COG1940	carbohydrate kinase activity
A9P82_RS14865	COG0157	Belongs to the NadC ModD family
A9P82_RS14870	COG0023	Translation Initiation Factor
A9P82_RS14875	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A9P82_RS14880	COG1473	amidohydrolase
A9P82_RS14890	COG1136	(ABC) transporter
A9P82_RS14890	COG0577	efflux transmembrane transporter activity
A9P82_RS14895	COG1136	(ABC) transporter
A9P82_RS14910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A9P82_RS14925	COG1584	GPR1 FUN34 yaaH family protein
A9P82_RS14935	COG0488	(ABC) transporter
A9P82_RS14970	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A9P82_RS14975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A9P82_RS14980	COG0456	acetyltransferase
A9P82_RS14990	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A9P82_RS15000	COG0101	tRNA pseudouridine synthase activity
A9P82_RS15005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9P82_RS15015	COG3275	phosphorelay sensor kinase activity
A9P82_RS15020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A9P82_RS15030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A9P82_RS15040	COG1131	(ABC) transporter
A9P82_RS15045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A9P82_RS15050	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A9P82_RS15070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A9P82_RS15085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A9P82_RS15090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A9P82_RS15095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A9P82_RS15100	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A9P82_RS15105	COG0616	signal peptide processing
A9P82_RS15110	COG0215	cysteine-tRNA ligase activity
A9P82_RS15115	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A9P82_RS15125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9P82_RS15145	COG0494	nUDIX hydrolase
A9P82_RS15150	COG1611	Belongs to the LOG family
A9P82_RS15155	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A9P82_RS15165	COG0242	peptide deformylase activity
A9P82_RS15170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A9P82_RS15175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A9P82_RS15180	COG0156	8-amino-7-oxononanoate synthase activity
A9P82_RS15190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A9P82_RS15200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family