locus-tag	class	description
K9M52_RS00025	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K9M52_RS00035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K9M52_RS00095	COG2197	response regulator
K9M52_RS00105	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K9M52_RS00160	COG0702	epimerase
K9M52_RS00165	COG1629	transport
K9M52_RS00170	COG1069	ribulokinase activity
K9M52_RS00175	COG0738	Major facilitator superfamily
K9M52_RS00190	COG1609	Transcriptional regulator
K9M52_RS00205	COG1858	cytochrome C peroxidase
K9M52_RS00230	COG4771	TonB-dependent receptor
K9M52_RS00235	COG0702	epimerase
K9M52_RS00260	COG3511	phospholipase C
K9M52_RS00265	COG2081	HI0933 family
K9M52_RS00270	COG2271	Major facilitator Superfamily
K9M52_RS00280	COG1629	transport
K9M52_RS00290	COG1349	DNA-binding transcription factor activity
K9M52_RS00295	COG0406	alpha-ribazole phosphatase activity
K9M52_RS00300	COG1070	Carbohydrate kinase
K9M52_RS00305	COG1070	Carbohydrate kinase
K9M52_RS00310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9M52_RS00315	COG2814	Major facilitator Superfamily
K9M52_RS00325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS00330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS00340	COG3250	beta-galactosidase activity
K9M52_RS00375	COG1809	phosphosulfolactate synthase activity
K9M52_RS00385	COG3119	arylsulfatase activity
K9M52_RS00395	COG3940	Belongs to the glycosyl hydrolase 43 family
K9M52_RS00400	COG0702	epimerase
K9M52_RS00405	COG4771	TonB-dependent receptor
K9M52_RS00410	COG0745	RESPONSE REGULATOR receiver
K9M52_RS00410	COG2205	protein histidine kinase activity
K9M52_RS00410	COG3292	Two component regulator propeller
K9M52_RS00415	COG3292	Two component regulator propeller
K9M52_RS00415	COG2205	protein histidine kinase activity
K9M52_RS00415	COG0745	RESPONSE REGULATOR receiver
K9M52_RS00420	COG1595	DNA-templated transcription, initiation
K9M52_RS00440	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9M52_RS00445	COG4771	TonB-dependent receptor
K9M52_RS00450	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K9M52_RS00480	COG4771	TonB-dependent receptor
K9M52_RS00500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9M52_RS00505	COG0025	NhaP-type Na H and K H
K9M52_RS00510	COG1082	Xylose isomerase domain protein TIM barrel
K9M52_RS00525	COG4771	TonB-dependent receptor
K9M52_RS00550	COG1012	belongs to the aldehyde dehydrogenase family
K9M52_RS00555	COG1621	beta-fructofuranosidase activity
K9M52_RS00560	COG1285	pathogenesis
K9M52_RS00580	COG1472	Belongs to the glycosyl hydrolase 3 family
K9M52_RS00610	COG1629	transport
K9M52_RS00615	COG3119	arylsulfatase activity
K9M52_RS00625	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K9M52_RS00630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K9M52_RS00630	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9M52_RS00650	COG3291	Pkd domain containing protein
K9M52_RS00675	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9M52_RS00695	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K9M52_RS00705	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K9M52_RS00725	COG0584	glycerophosphoryl diester phosphodiesterase
K9M52_RS00730	COG3511	phospholipase C
K9M52_RS00735	COG0702	epimerase
K9M52_RS00740	COG1629	transport
K9M52_RS00745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K9M52_RS00750	COG1349	DNA-binding transcription factor activity
K9M52_RS00760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K9M52_RS00765	COG1595	DNA-templated transcription, initiation
K9M52_RS00790	COG1629	transport
K9M52_RS00825	COG3119	arylsulfatase activity
K9M52_RS00845	COG2610	gluconate transmembrane transporter activity
K9M52_RS00860	COG1846	Transcriptional regulator
K9M52_RS00875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9M52_RS00880	COG0477	Major facilitator Superfamily
K9M52_RS00880	COG2814	Major facilitator Superfamily
K9M52_RS00890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K9M52_RS00895	COG1490	D-aminoacyl-tRNA deacylase activity
K9M52_RS00900	COG1694	Mazg nucleotide pyrophosphohydrolase
K9M52_RS00910	COG1702	phosphate starvation-inducible protein PhoH
K9M52_RS00920	COG3340	Belongs to the peptidase S51 family
K9M52_RS00940	COG1127	ABC transporter
K9M52_RS00945	COG4221	oxidoreductase activity
K9M52_RS00955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9M52_RS00960	COG0297	glycogen (starch) synthase activity
K9M52_RS00965	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K9M52_RS00980	COG0443	Heat shock 70 kDa protein
K9M52_RS00985	COG2877	3-deoxy-8-phosphooctulonate synthase activity
K9M52_RS00990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K9M52_RS01000	COG0138	bifunctional purine biosynthesis protein purh
K9M52_RS01005	COG0049	tRNA binding
K9M52_RS01010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K9M52_RS01045	COG1595	DNA-templated transcription, initiation
K9M52_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS01080	COG0577	efflux transmembrane transporter activity
K9M52_RS01115	COG4804	nuclease activity
K9M52_RS01140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K9M52_RS01140	COG0574	Belongs to the PEP-utilizing enzyme family
K9M52_RS01145	COG1522	sequence-specific DNA binding
K9M52_RS01175	COG2003	Belongs to the UPF0758 family
K9M52_RS01185	COG0792	nuclease activity
K9M52_RS01260	COG1476	TRANSCRIPTIONal
K9M52_RS01305	COG1595	DNA-templated transcription, initiation
K9M52_RS01315	COG1629	transport
K9M52_RS01315	COG4206	TonB-dependent receptor
K9M52_RS01335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS01340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS01355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K9M52_RS01435	COG3486	L-lysine 6-monooxygenase (NADPH) activity
K9M52_RS01475	COG4771	TonB-dependent receptor
K9M52_RS01500	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K9M52_RS01520	COG3250	beta-galactosidase activity
K9M52_RS01560	COG4771	TonB-dependent receptor
K9M52_RS01565	COG0702	epimerase
K9M52_RS01570	COG3118	belongs to the thioredoxin family
K9M52_RS01590	COG3250	beta-galactosidase activity
K9M52_RS01725	COG4974	Belongs to the 'phage' integrase family
K9M52_RS01735	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K9M52_RS01745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS01760	COG0436	Aminotransferase
K9M52_RS01765	COG1733	regulation of RNA biosynthetic process
K9M52_RS01775	COG1803	Methylglyoxal synthase
K9M52_RS01795	COG0183	Belongs to the thiolase family
K9M52_RS01800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K9M52_RS01810	COG0431	NADPH-dependent FMN reductase
K9M52_RS01815	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
K9M52_RS01820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K9M52_RS01830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K9M52_RS01845	COG0022	dehydrogenase e1 component
K9M52_RS01855	COG4948	Mandelate Racemase Muconate Lactonizing
K9M52_RS01880	COG0702	epimerase
K9M52_RS01885	COG4206	TonB-dependent receptor
K9M52_RS01885	COG1629	transport
K9M52_RS01905	COG1609	Transcriptional regulator
K9M52_RS01915	COG1472	Belongs to the glycosyl hydrolase 3 family
K9M52_RS01920	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K9M52_RS01925	COG1609	Transcriptional regulator
K9M52_RS01930	COG1904	glucuronate isomerase
K9M52_RS01940	COG0800	Aldolase
K9M52_RS01945	COG2271	Major facilitator Superfamily
K9M52_RS01950	COG2755	lipolytic protein G-D-S-L family
K9M52_RS01950	COG0657	acetylesterase activity
K9M52_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS01960	COG1312	Catalyzes the dehydration of D-mannonate
K9M52_RS01975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K9M52_RS01980	COG5002	protein histidine kinase activity
K9M52_RS02005	COG1231	oxidoreductase activity
K9M52_RS02015	COG0247	lactate metabolic process
K9M52_RS02015	COG2181	nitrate reductase activity
K9M52_RS02025	COG3655	Transcriptional regulator
K9M52_RS02030	COG1131	(ABC) transporter
K9M52_RS02040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K9M52_RS02050	COG1774	PSP1 C-terminal conserved region
K9M52_RS02055	COG0470	DNA polymerase III
K9M52_RS02075	COG4804	nuclease activity
K9M52_RS02095	COG0577	efflux transmembrane transporter activity
K9M52_RS02105	COG2514	catechol 2,3-dioxygenase activity
K9M52_RS02135	COG0516	GMP reductase activity
K9M52_RS02135	COG0517	IMP dehydrogenase activity
K9M52_RS02160	COG2890	protein-(glutamine-N5) methyltransferase activity
K9M52_RS02175	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
K9M52_RS02180	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K9M52_RS02190	COG0525	valine-tRNA ligase activity
K9M52_RS02210	COG0791	NLP P60 protein
K9M52_RS02225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9M52_RS02230	COG1090	epimerase
K9M52_RS02235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K9M52_RS02235	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K9M52_RS02250	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
K9M52_RS02255	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS02270	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K9M52_RS02275	COG1609	Transcriptional regulator
K9M52_RS02280	COG4948	Mandelate Racemase Muconate Lactonizing
K9M52_RS02290	COG1428	Deoxynucleoside kinase
K9M52_RS02295	COG0180	Tryptophanyl-tRNA synthetase
K9M52_RS02300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K9M52_RS02310	COG2022	thiamine diphosphate biosynthetic process
K9M52_RS02315	COG0352	thiamine-phosphate diphosphorylase activity
K9M52_RS02320	COG0351	phosphomethylpyrimidine kinase
K9M52_RS02330	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K9M52_RS02340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9M52_RS02340	COG0723	plastoquinol--plastocyanin reductase activity
K9M52_RS02350	COG0438	transferase activity, transferring glycosyl groups
K9M52_RS02370	COG1252	NADH dehydrogenase
K9M52_RS02385	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
K9M52_RS02410	COG3685	Protein conserved in bacteria
K9M52_RS02440	COG2204	response regulator
K9M52_RS02445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K9M52_RS02455	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
K9M52_RS02460	COG3387	PFAM Glycoside hydrolase 15-related
K9M52_RS02515	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS02520	COG1074	ATP-dependent DNA helicase activity
K9M52_RS02525	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
K9M52_RS02530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9M52_RS02600	COG0359	binds to the 23S rRNA
K9M52_RS02605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K9M52_RS02610	COG0360	Binds together with S18 to 16S ribosomal RNA
K9M52_RS02615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K9M52_RS02630	COG0473	3-isopropylmalate dehydrogenase activity
K9M52_RS02645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K9M52_RS02655	COG4771	TonB-dependent receptor
K9M52_RS02660	COG0702	epimerase
K9M52_RS02675	COG2271	Major facilitator Superfamily
K9M52_RS02695	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K9M52_RS02715	COG0475	glutathione-regulated potassium exporter activity
K9M52_RS02715	COG0589	response to stress
K9M52_RS02725	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
K9M52_RS02755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K9M52_RS02760	COG1809	phosphosulfolactate synthase activity
K9M52_RS02775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K9M52_RS02780	COG0594	ribonuclease P activity
K9M52_RS02785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
K9M52_RS02790	COG0438	transferase activity, transferring glycosyl groups
K9M52_RS02865	COG2197	response regulator
K9M52_RS02870	COG0577	efflux transmembrane transporter activity
K9M52_RS02905	COG2130	NADP-dependent
K9M52_RS02920	COG1917	Cupin 2, conserved barrel domain protein
K9M52_RS02920	COG2207	Transcriptional regulator
K9M52_RS02925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9M52_RS02950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9M52_RS02955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9M52_RS02970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9M52_RS02970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9M52_RS02975	COG0492	ferredoxin-NADP+ reductase activity
K9M52_RS02985	COG1609	Transcriptional regulator
K9M52_RS03060	COG1609	Transcriptional regulator
K9M52_RS03065	COG1082	Xylose isomerase domain protein TIM barrel
K9M52_RS03090	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K9M52_RS03100	COG2814	Major facilitator Superfamily
K9M52_RS03100	COG0477	Major facilitator Superfamily
K9M52_RS03105	COG1082	Xylose isomerase domain protein TIM barrel
K9M52_RS03120	COG1609	Transcriptional regulator
K9M52_RS03125	COG4206	TonB-dependent receptor
K9M52_RS03125	COG1629	transport
K9M52_RS03130	COG0561	phosphatase activity
K9M52_RS03160	COG0346	lactoylglutathione lyase activity
K9M52_RS03165	COG0667	Aldo Keto reductase
K9M52_RS03170	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9M52_RS03185	COG4206	TonB-dependent receptor
K9M52_RS03190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9M52_RS03190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
K9M52_RS03195	COG2166	iron-sulfur cluster assembly
K9M52_RS03220	COG2132	Multicopper oxidase
K9M52_RS03245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS03260	COG0420	3'-5' exonuclease activity
K9M52_RS03295	COG1185	polyribonucleotide nucleotidyltransferase activity
K9M52_RS03300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K9M52_RS03305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K9M52_RS03320	COG0259	pyridoxamine-phosphate oxidase activity
K9M52_RS03325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K9M52_RS03335	COG2095	MarC family integral membrane protein
K9M52_RS03340	COG0589	response to stress
K9M52_RS03345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K9M52_RS03350	COG2885	chlorophyll binding
K9M52_RS03360	COG0745	RESPONSE REGULATOR receiver
K9M52_RS03375	COG1566	PFAM secretion protein HlyD family protein
K9M52_RS03380	COG0542	response to heat
K9M52_RS03410	COG2271	Major facilitator Superfamily
K9M52_RS03420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9M52_RS03430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9M52_RS03445	COG0702	epimerase
K9M52_RS03450	COG4771	TonB-dependent receptor
K9M52_RS03455	COG2186	Transcriptional regulator
K9M52_RS03495	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K9M52_RS03505	COG0671	phosphoesterase, PA-phosphatase related
K9M52_RS03520	COG0586	Pfam SNARE associated Golgi protein
K9M52_RS03525	COG1301	dicarboxylic acid transport
K9M52_RS03530	COG0531	amino acid
K9M52_RS03535	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K9M52_RS03545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9M52_RS03560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K9M52_RS03580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K9M52_RS03610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS03615	COG1012	belongs to the aldehyde dehydrogenase family
K9M52_RS03680	COG2261	transglycosylase associated protein
K9M52_RS03690	COG1914	H( )-stimulated, divalent metal cation uptake system
K9M52_RS03695	COG1530	ribonuclease E activity
K9M52_RS03745	COG1950	PFAM Membrane protein of
K9M52_RS03775	COG0659	secondary active sulfate transmembrane transporter activity
K9M52_RS03780	COG0577	efflux transmembrane transporter activity
K9M52_RS03795	COG1629	transport
K9M52_RS03805	COG3250	beta-galactosidase activity
K9M52_RS03825	COG0673	inositol 2-dehydrogenase activity
K9M52_RS03830	COG2814	Major facilitator Superfamily
K9M52_RS03860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9M52_RS03865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9M52_RS03930	COG3940	Belongs to the glycosyl hydrolase 43 family
K9M52_RS03935	COG2207	Transcriptional regulator
K9M52_RS03935	COG0662	Cupin 2, conserved barrel domain protein
K9M52_RS03940	COG3250	beta-galactosidase activity
K9M52_RS03945	COG3250	beta-galactosidase activity
K9M52_RS03965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9M52_RS03995	COG3250	beta-galactosidase activity
K9M52_RS04045	COG0702	epimerase
K9M52_RS04050	COG4771	TonB-dependent receptor
K9M52_RS04080	COG0702	epimerase
K9M52_RS04085	COG1629	transport
K9M52_RS04085	COG4206	TonB-dependent receptor
K9M52_RS04090	COG0745	RESPONSE REGULATOR receiver
K9M52_RS04095	COG5002	protein histidine kinase activity
K9M52_RS04105	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
K9M52_RS04110	COG1349	DNA-binding transcription factor activity
K9M52_RS04125	COG4977	sequence-specific DNA binding
K9M52_RS04140	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K9M52_RS04150	COG1858	cytochrome C peroxidase
K9M52_RS04480	COG1132	(ABC) transporter
K9M52_RS04495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K9M52_RS04505	COG0165	Argininosuccinate lyase
K9M52_RS04510	COG3265	gluconokinase activity
K9M52_RS04515	COG3548	integral membrane protein
K9M52_RS04530	COG3655	Transcriptional regulator
K9M52_RS04540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K9M52_RS04555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K9M52_RS04560	COG0137	argininosuccinate synthase activity
K9M52_RS04575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K9M52_RS04585	COG0517	IMP dehydrogenase activity
K9M52_RS04585	COG0516	GMP reductase activity
K9M52_RS04595	COG0542	response to heat
K9M52_RS04605	COG0659	secondary active sulfate transmembrane transporter activity
K9M52_RS04615	COG3781	membrane
K9M52_RS04625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K9M52_RS04640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K9M52_RS04650	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K9M52_RS04665	COG1522	sequence-specific DNA binding
K9M52_RS04685	COG2304	oxidoreductase activity
K9M52_RS04690	COG0481	GTPase activity
K9M52_RS04695	COG3409	Peptidoglycan-binding domain 1 protein
K9M52_RS04695	COG3757	hydrolase, family 25
K9M52_RS04705	COG1666	GTP binding
K9M52_RS04720	COG0424	maF-like protein
K9M52_RS04755	COG1137	ATPase activity
K9M52_RS04765	COG1393	Belongs to the ArsC family
K9M52_RS04770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K9M52_RS04785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K9M52_RS04790	COG1663	tetraacyldisaccharide 4'-kinase activity
K9M52_RS04795	COG0557	exoribonuclease II activity
K9M52_RS04800	COG1193	negative regulation of DNA recombination
K9M52_RS04825	COG0793	Belongs to the peptidase S41A family
K9M52_RS04860	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K9M52_RS04860	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
K9M52_RS04915	COG0505	Belongs to the CarA family
K9M52_RS04920	COG1418	mRNA catabolic process
K9M52_RS04925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K9M52_RS04940	COG0776	regulation of translation
K9M52_RS04950	COG0708	Exodeoxyribonuclease III
K9M52_RS04955	COG1181	Belongs to the D-alanine--D-alanine ligase family
K9M52_RS04960	COG2815	serine threonine protein kinase
K9M52_RS04960	COG0515	serine threonine protein kinase
K9M52_RS04965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K9M52_RS05015	COG0783	Belongs to the Dps family
K9M52_RS05030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K9M52_RS05055	COG4771	TonB-dependent receptor
K9M52_RS05075	COG3119	arylsulfatase activity
K9M52_RS05085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
K9M52_RS05090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K9M52_RS05100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9M52_RS05105	COG0179	Fumarylacetoacetate (FAA) hydrolase
K9M52_RS05115	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K9M52_RS05125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9M52_RS05140	COG3119	arylsulfatase activity
K9M52_RS05150	COG1216	Glycosyl transferase, family 2
K9M52_RS05155	COG5039	Polysaccharide pyruvyl transferase
K9M52_RS05175	COG0405	Gamma-glutamyltransferase
K9M52_RS05200	COG0602	queuosine metabolic process
K9M52_RS05205	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K9M52_RS05230	COG1902	pentaerythritol trinitrate reductase activity
K9M52_RS05240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K9M52_RS05280	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
K9M52_RS05295	COG0640	Transcriptional regulator
K9M52_RS05300	COG0196	riboflavin kinase activity
K9M52_RS05305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K9M52_RS05315	COG0297	glycogen (starch) synthase activity
K9M52_RS05320	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K9M52_RS05335	COG0848	biopolymer transport protein
K9M52_RS05340	COG0811	peptide transport
K9M52_RS05375	COG4771	TonB-dependent receptor
K9M52_RS05390	COG0702	epimerase
K9M52_RS05395	COG1629	transport
K9M52_RS05400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K9M52_RS05405	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K9M52_RS05410	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K9M52_RS05415	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K9M52_RS05420	COG0356	it plays a direct role in the translocation of protons across the membrane
K9M52_RS05430	COG0730	response to heat
K9M52_RS05435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
K9M52_RS05450	COG1253	flavin adenine dinucleotide binding
K9M52_RS05455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS05470	COG4654	Cytochrome c, class I
K9M52_RS05475	COG0590	tRNA wobble adenosine to inosine editing
K9M52_RS05480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K9M52_RS05495	COG2177	Part of the ABC transporter FtsEX involved in
K9M52_RS05500	COG0495	leucyl-tRNA aminoacylation
K9M52_RS05510	COG0577	efflux transmembrane transporter activity
K9M52_RS05510	COG1136	(ABC) transporter
K9M52_RS05525	COG2264	protein methyltransferase activity
K9M52_RS05530	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K9M52_RS05545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K9M52_RS05555	COG3457	Alanine racemase
K9M52_RS05565	COG2197	response regulator
K9M52_RS05570	COG4585	Histidine kinase
K9M52_RS05575	COG3345	alpha-galactosidase
K9M52_RS05580	COG0416	fatty acid biosynthetic process
K9M52_RS05600	COG3158	transport of potassium into the cell
K9M52_RS05610	COG0047	phosphoribosylformylglycinamidine synthase activity
K9M52_RS05625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K9M52_RS05630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K9M52_RS05640	COG0492	ferredoxin-NADP+ reductase activity
K9M52_RS05645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K9M52_RS05650	COG0484	heat shock protein binding
K9M52_RS05675	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K9M52_RS05680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K9M52_RS05685	COG2003	Belongs to the UPF0758 family
K9M52_RS05700	COG0038	chloride channel
K9M52_RS05705	COG4774	siderophore transport
K9M52_RS05725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K9M52_RS05735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K9M52_RS05740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K9M52_RS05750	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K9M52_RS05755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K9M52_RS05775	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K9M52_RS05780	COG1132	(ABC) transporter
K9M52_RS05795	COG0154	amidase activity
K9M52_RS05800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K9M52_RS05805	COG3239	Fatty acid desaturase
K9M52_RS05810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K9M52_RS05825	COG0514	ATP-dependent DNA helicase (RecQ)
K9M52_RS05830	COG4977	sequence-specific DNA binding
K9M52_RS05830	COG1917	Cupin 2, conserved barrel domain protein
K9M52_RS05850	COG3408	Glycogen debranching enzyme
K9M52_RS05855	COG0702	epimerase
K9M52_RS05860	COG4771	TonB-dependent receptor
K9M52_RS05870	COG1528	Iron-storage protein
K9M52_RS05875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9M52_RS05885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K9M52_RS05890	COG0052	Belongs to the universal ribosomal protein uS2 family
K9M52_RS05895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K9M52_RS05900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K9M52_RS05905	COG1187	pseudouridine synthase activity
K9M52_RS05915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K9M52_RS05925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K9M52_RS05940	COG0163	prenyltransferase activity
K9M52_RS05950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9M52_RS05960	COG3275	phosphorelay sensor kinase activity
K9M52_RS05965	COG3279	Response regulator of the LytR AlgR family
K9M52_RS05970	COG0460	homoserine dehydrogenase
K9M52_RS05970	COG0527	aspartate kinase activity
K9M52_RS05975	COG0083	homoserine kinase activity
K9M52_RS05985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9M52_RS05990	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K9M52_RS05995	COG1981	membrane
K9M52_RS06025	COG1610	YqeY-like protein
K9M52_RS06045	COG2885	chlorophyll binding
K9M52_RS06070	COG1960	acyl-CoA dehydrogenase activity
K9M52_RS06075	COG0504	CTP synthase activity
K9M52_RS06090	COG0357	Ribosomal RNA small subunit methyltransferase G
K9M52_RS06095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K9M52_RS06100	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
K9M52_RS06115	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K9M52_RS06200	COG3250	beta-galactosidase activity
K9M52_RS06230	COG2160	L-arabinose isomerase activity
K9M52_RS06240	COG1069	ribulokinase activity
K9M52_RS06245	COG2207	Transcriptional regulator
K9M52_RS06250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9M52_RS06260	COG3938	Belongs to the proline racemase family
K9M52_RS06270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9M52_RS06275	COG0006	proline dipeptidase activity
K9M52_RS06290	COG4771	TonB-dependent receptor
K9M52_RS06295	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9M52_RS06345	COG2910	NAD(P)H-binding
K9M52_RS06365	COG0402	S-adenosylhomocysteine deaminase activity
K9M52_RS06370	COG0402	S-adenosylhomocysteine deaminase activity
K9M52_RS06380	COG0673	inositol 2-dehydrogenase activity
K9M52_RS06390	COG0673	inositol 2-dehydrogenase activity
K9M52_RS06425	COG2079	MmgE PrpD family protein
K9M52_RS06435	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K9M52_RS06440	COG1024	Enoyl-CoA hydratase
K9M52_RS06475	COG1595	DNA-templated transcription, initiation
K9M52_RS06485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9M52_RS06520	COG0732	type I restriction modification DNA specificity domain
K9M52_RS06585	COG2873	o-acetylhomoserine
K9M52_RS06590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9M52_RS06595	COG0460	homoserine dehydrogenase
K9M52_RS06600	COG1473	amidohydrolase
K9M52_RS06605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K9M52_RS06620	COG0085	RNA polymerase activity
K9M52_RS06665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K9M52_RS06670	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K9M52_RS06675	COG4948	Mandelate Racemase Muconate Lactonizing
K9M52_RS06680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K9M52_RS06710	COG0101	tRNA pseudouridine synthase activity
K9M52_RS06720	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K9M52_RS06725	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
K9M52_RS06735	COG4221	oxidoreductase activity
K9M52_RS06755	COG0314	molybdopterin synthase activity
K9M52_RS06765	COG0243	molybdopterin cofactor binding
K9M52_RS06780	COG2837	iron assimilation
K9M52_RS06790	COG0746	molybdenum cofactor guanylyltransferase activity
K9M52_RS06795	COG0746	molybdenum cofactor guanylyltransferase activity
K9M52_RS06795	COG0315	cyclic pyranopterin monophosphate synthase activity
K9M52_RS06800	COG0303	'Molybdopterin
K9M52_RS06805	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K9M52_RS06815	COG0577	efflux transmembrane transporter activity
K9M52_RS06820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS06825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS06835	COG4771	TonB-dependent receptor
K9M52_RS06840	COG3275	phosphorelay sensor kinase activity
K9M52_RS06865	COG0587	DNA-directed DNA polymerase activity
K9M52_RS06880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K9M52_RS06885	COG0657	acetylesterase activity
K9M52_RS06885	COG2755	lipolytic protein G-D-S-L family
K9M52_RS06915	COG1850	ribulose-bisphosphate carboxylase activity
K9M52_RS06920	COG1218	3'(2'),5'-bisphosphate nucleotidase
K9M52_RS06940	COG1131	(ABC) transporter
K9M52_RS06955	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K9M52_RS06960	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K9M52_RS06965	COG1136	(ABC) transporter
K9M52_RS06970	COG2096	Adenosyltransferase
K9M52_RS06975	COG1136	(ABC) transporter
K9M52_RS07010	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K9M52_RS07015	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K9M52_RS07020	COG0336	Belongs to the RNA methyltransferase TrmD family
K9M52_RS07035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K9M52_RS07040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9M52_RS07065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS07085	COG4771	TonB-dependent receptor
K9M52_RS07100	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K9M52_RS07125	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS07130	COG0288	reversible hydration of carbon dioxide
K9M52_RS07140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K9M52_RS07145	COG0328	RNA-DNA hybrid ribonuclease activity
K9M52_RS07150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K9M52_RS07160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K9M52_RS07160	COG0662	Cupin 2, conserved barrel domain protein
K9M52_RS07165	COG0330	HflC and HflK could
K9M52_RS07170	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K9M52_RS07185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K9M52_RS07195	COG0433	COG0433 Predicted ATPase
K9M52_RS07200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K9M52_RS07225	COG0824	Thioesterase
K9M52_RS07245	COG4651	solute:proton antiporter activity
K9M52_RS07245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K9M52_RS07265	COG1595	DNA-templated transcription, initiation
K9M52_RS07275	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K9M52_RS07280	COG0563	adenylate kinase activity
K9M52_RS07290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K9M52_RS07305	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K9M52_RS07310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K9M52_RS07335	COG2382	esterase
K9M52_RS07340	COG2211	Major facilitator Superfamily
K9M52_RS07340	COG2190	(PTS) system
K9M52_RS07350	COG0366	Alpha amylase catalytic
K9M52_RS07365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9M52_RS07370	COG1629	transport
K9M52_RS07370	COG4206	TonB-dependent receptor
K9M52_RS07375	COG1609	Transcriptional regulator
K9M52_RS07405	COG0577	efflux transmembrane transporter activity
K9M52_RS07405	COG1136	(ABC) transporter
K9M52_RS07410	COG0577	efflux transmembrane transporter activity
K9M52_RS07415	COG0577	efflux transmembrane transporter activity
K9M52_RS07415	COG1136	(ABC) transporter
K9M52_RS07425	COG0577	efflux transmembrane transporter activity
K9M52_RS07425	COG1136	(ABC) transporter
K9M52_RS07430	COG1136	(ABC) transporter
K9M52_RS07440	COG0577	efflux transmembrane transporter activity
K9M52_RS07460	COG3852	Histidine kinase
K9M52_RS07480	COG0300	oxidoreductase activity
K9M52_RS07490	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
K9M52_RS07495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K9M52_RS07505	COG0004	ammonium transporteR
K9M52_RS07515	COG0779	Required for maturation of 30S ribosomal subunits
K9M52_RS07520	COG0195	Participates in both transcription termination and antitermination
K9M52_RS07520	COG2251	uridine kinase activity
K9M52_RS07525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K9M52_RS07530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9M52_RS07540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K9M52_RS07575	COG2972	Histidine kinase
K9M52_RS07590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K9M52_RS07595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K9M52_RS07615	COG3142	Participates in the control of copper homeostasis
K9M52_RS07620	COG0222	ribosome binding
K9M52_RS07625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K9M52_RS07630	COG0081	regulation of translation
K9M52_RS07635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K9M52_RS07655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9M52_RS07665	COG0791	NLP P60 protein
K9M52_RS07665	COG1388	LysM domain
K9M52_RS07670	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
K9M52_RS07670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K9M52_RS07710	COG4948	Mandelate Racemase Muconate Lactonizing
K9M52_RS07725	COG4771	TonB-dependent receptor
K9M52_RS07740	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9M52_RS07775	COG0702	epimerase
K9M52_RS07780	COG4771	TonB-dependent receptor
K9M52_RS07785	COG0457	Tetratricopeptide repeat
K9M52_RS07790	COG0477	Major facilitator Superfamily
K9M52_RS07790	COG2814	Major facilitator Superfamily
K9M52_RS07820	COG1428	Deoxynucleoside kinase
K9M52_RS07830	COG0069	glutamate synthase activity
K9M52_RS07835	COG0009	L-threonylcarbamoyladenylate synthase
K9M52_RS07850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K9M52_RS07855	COG0084	hydrolase, TatD family'
K9M52_RS07915	COG4771	TonB-dependent receptor
K9M52_RS07950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K9M52_RS07980	COG1629	transport
K9M52_RS07995	COG0577	efflux transmembrane transporter activity
K9M52_RS08025	COG3119	arylsulfatase activity
K9M52_RS08040	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS08070	COG1629	transport
K9M52_RS08080	COG1629	transport
K9M52_RS08085	COG0702	epimerase
K9M52_RS08110	COG1629	transport
K9M52_RS08140	COG0246	Mannitol dehydrogenase
K9M52_RS08145	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9M52_RS08150	COG1129	ABC transporter
K9M52_RS08180	COG1629	transport
K9M52_RS08205	COG1472	Belongs to the glycosyl hydrolase 3 family
K9M52_RS08235	COG0702	epimerase
K9M52_RS08240	COG4771	TonB-dependent receptor
K9M52_RS08245	COG2814	Major facilitator Superfamily
K9M52_RS08275	COG4771	TonB-dependent receptor
K9M52_RS08290	COG1051	belongs to the nudix hydrolase family
K9M52_RS08330	COG4804	nuclease activity
K9M52_RS08360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K9M52_RS08385	COG1011	Hydrolase
K9M52_RS08395	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K9M52_RS08400	COG1612	heme a metabolic process
K9M52_RS08405	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K9M52_RS08410	COG0598	Magnesium transport protein CorA
K9M52_RS08415	COG0772	Belongs to the SEDS family
K9M52_RS08420	COG0768	penicillin binding
K9M52_RS08430	COG1792	Involved in formation and maintenance of cell shape
K9M52_RS08435	COG1077	Cell shape determining protein MreB Mrl
K9M52_RS08485	COG3661	Belongs to the glycosyl hydrolase 67 family
K9M52_RS08495	COG1629	transport
K9M52_RS08500	COG1082	Xylose isomerase domain protein TIM barrel
K9M52_RS08505	COG3507	Belongs to the glycosyl hydrolase 43 family
K9M52_RS08505	COG3693	PFAM glycoside hydrolase, family 10
K9M52_RS08505	COG2382	esterase
K9M52_RS08535	COG4771	TonB-dependent receptor
K9M52_RS08540	COG3507	Belongs to the glycosyl hydrolase 43 family
K9M52_RS08560	COG0657	acetylesterase activity
K9M52_RS08560	COG2755	lipolytic protein G-D-S-L family
K9M52_RS08565	COG0657	acetylesterase activity
K9M52_RS08570	COG2382	esterase
K9M52_RS08575	COG3693	PFAM glycoside hydrolase, family 10
K9M52_RS08575	COG2382	esterase
K9M52_RS08580	COG1472	Belongs to the glycosyl hydrolase 3 family
K9M52_RS08585	COG3507	Belongs to the glycosyl hydrolase 43 family
K9M52_RS08600	COG1501	Belongs to the glycosyl hydrolase 31 family
K9M52_RS08615	COG0702	epimerase
K9M52_RS08620	COG4771	TonB-dependent receptor
K9M52_RS08625	COG0477	Major facilitator Superfamily
K9M52_RS08625	COG2814	Major facilitator Superfamily
K9M52_RS08630	COG2115	Belongs to the xylose isomerase family
K9M52_RS08635	COG1070	Carbohydrate kinase
K9M52_RS08660	COG1472	Belongs to the glycosyl hydrolase 3 family
K9M52_RS08665	COG1741	Belongs to the pirin family
K9M52_RS08670	COG0346	lactoylglutathione lyase activity
K9M52_RS08680	COG0346	lactoylglutathione lyase activity
K9M52_RS08705	COG0456	acetyltransferase
K9M52_RS08710	COG2235	arginine
K9M52_RS08730	COG0335	large ribosomal subunit rRNA binding
K9M52_RS08740	COG0509	glycine decarboxylation via glycine cleavage system
K9M52_RS08745	COG0436	Aminotransferase
K9M52_RS08755	COG1760	l-serine dehydratase
K9M52_RS08765	COG1234	tRNA 3'-trailer cleavage
K9M52_RS08770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K9M52_RS08775	COG0745	RESPONSE REGULATOR receiver
K9M52_RS08775	COG2205	protein histidine kinase activity
K9M52_RS08775	COG3292	Two component regulator propeller
K9M52_RS08780	COG1501	Belongs to the glycosyl hydrolase 31 family
K9M52_RS08785	COG4771	TonB-dependent receptor
K9M52_RS08805	COG1733	regulation of RNA biosynthetic process
K9M52_RS08810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K9M52_RS08835	COG0673	inositol 2-dehydrogenase activity
K9M52_RS08850	COG2211	Major facilitator Superfamily
K9M52_RS08880	COG2217	Heavy metal translocating P-type atpase
K9M52_RS08895	COG0215	cysteine-tRNA ligase activity
K9M52_RS08905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9M52_RS08920	COG0571	ribonuclease III activity
K9M52_RS08925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K9M52_RS08935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K9M52_RS08940	COG2153	protein acetylation
K9M52_RS08955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K9M52_RS08960	COG2315	Protein conserved in bacteria
K9M52_RS08980	COG4771	TonB-dependent receptor
K9M52_RS08990	COG0326	Molecular chaperone. Has ATPase activity
K9M52_RS09010	COG0592	DNA-directed DNA polymerase activity
K9M52_RS09020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K9M52_RS09040	COG1215	transferase activity, transferring glycosyl groups
K9M52_RS09055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K9M52_RS09060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9M52_RS09065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9M52_RS09095	COG3279	Response regulator of the LytR AlgR family
K9M52_RS09135	COG0387	Pfam Sodium calcium exchanger
K9M52_RS09140	COG4821	SIS domain
K9M52_RS09150	COG1940	carbohydrate kinase activity
K9M52_RS09155	COG1349	DNA-binding transcription factor activity
K9M52_RS09165	COG5297	Belongs to the glycosyl hydrolase family 6
K9M52_RS09165	COG3250	beta-galactosidase activity
K9M52_RS09175	COG4771	TonB-dependent receptor
K9M52_RS09185	COG1335	isochorismatase
K9M52_RS09205	COG3940	Belongs to the glycosyl hydrolase 43 family
K9M52_RS09210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9M52_RS09220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9M52_RS09230	COG1104	cysteine desulfurase activity
K9M52_RS09235	COG2207	Transcriptional regulator
K9M52_RS09275	COG1022	Amp-dependent synthetase and ligase
K9M52_RS09280	COG0151	Belongs to the GarS family
K9M52_RS09295	COG2076	Multidrug Resistance protein
K9M52_RS09305	COG1597	lipid kinase activity
K9M52_RS09315	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K9M52_RS09325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K9M52_RS09330	COG0445	tRNA wobble uridine modification
K9M52_RS09340	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K9M52_RS09345	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9M52_RS09365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K9M52_RS09400	COG1629	transport
K9M52_RS09400	COG4206	TonB-dependent receptor
K9M52_RS09420	COG4206	TonB-dependent receptor
K9M52_RS09420	COG1629	transport
K9M52_RS09430	COG4771	TonB-dependent receptor
K9M52_RS09440	COG2884	Cell division ATP-binding protein ftsE
K9M52_RS09455	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K9M52_RS09460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K9M52_RS09480	COG0113	porphobilinogen synthase activity
K9M52_RS09485	COG0408	coproporphyrinogen oxidase activity
K9M52_RS09490	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K9M52_RS09500	COG0181	hydroxymethylbilane synthase activity
K9M52_RS09505	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K9M52_RS09510	COG1940	carbohydrate kinase activity
K9M52_RS09515	COG4206	TonB-dependent receptor
K9M52_RS09515	COG1629	transport
K9M52_RS09540	COG0343	queuine tRNA-ribosyltransferase activity
K9M52_RS09545	COG0025	NhaP-type Na H and K H
K9M52_RS09555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K9M52_RS09560	COG0302	gtp cyclohydrolase
K9M52_RS09575	COG0456	acetyltransferase
K9M52_RS09615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K9M52_RS09620	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
K9M52_RS09635	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
K9M52_RS09665	COG3011	Protein conserved in bacteria
K9M52_RS09680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K9M52_RS09690	COG0537	adenosine 5'-monophosphoramidase activity
K9M52_RS09695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9M52_RS09695	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K9M52_RS09710	COG0402	S-adenosylhomocysteine deaminase activity
K9M52_RS09715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9M52_RS09720	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K9M52_RS09725	COG0688	phosphatidylethanolamine metabolic process
K9M52_RS09730	COG4589	Belongs to the CDS family
K9M52_RS09740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9M52_RS09745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K9M52_RS09750	COG3537	Alpha-1,2-mannosidase
K9M52_RS09770	COG3408	Glycogen debranching enzyme
K9M52_RS09785	COG1629	transport
K9M52_RS09785	COG4206	TonB-dependent receptor
K9M52_RS09790	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9M52_RS09795	COG1609	Transcriptional regulator
K9M52_RS09800	COG3408	Glycogen debranching enzyme
K9M52_RS09800	COG3119	arylsulfatase activity
K9M52_RS09805	COG1629	transport
K9M52_RS09805	COG4206	TonB-dependent receptor
K9M52_RS09825	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS09825	COG3347	Dehydrogenase
K9M52_RS09830	COG4952	isomerase
K9M52_RS09840	COG1304	FMN binding
K9M52_RS09845	COG4771	TonB-dependent receptor
K9M52_RS09850	COG0702	epimerase
K9M52_RS09865	COG4771	TonB-dependent receptor
K9M52_RS09905	COG3254	rhamnose metabolic process
K9M52_RS09910	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K9M52_RS09930	COG4771	TonB-dependent receptor
K9M52_RS09935	COG0702	epimerase
K9M52_RS09950	COG1629	transport
K9M52_RS09960	COG2755	lipolytic protein G-D-S-L family
K9M52_RS09965	COG2755	lipolytic protein G-D-S-L family
K9M52_RS09970	COG3401	FG-GAP repeat protein
K9M52_RS09975	COG3250	beta-galactosidase activity
K9M52_RS09980	COG3250	beta-galactosidase activity
K9M52_RS09995	COG3250	beta-galactosidase activity
K9M52_RS10000	COG4771	TonB-dependent receptor
K9M52_RS10015	COG1629	transport
K9M52_RS10030	COG3279	Response regulator of the LytR AlgR family
K9M52_RS10055	COG1629	transport
K9M52_RS10055	COG4206	TonB-dependent receptor
K9M52_RS10065	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9M52_RS10070	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9M52_RS10080	COG0649	NAD binding
K9M52_RS10085	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
K9M52_RS10100	COG1034	ATP synthesis coupled electron transport
K9M52_RS10105	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K9M52_RS10110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9M52_RS10115	COG0839	Belongs to the complex I subunit 6 family
K9M52_RS10120	COG0713	ATP synthesis coupled electron transport
K9M52_RS10125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K9M52_RS10135	COG1007	ATP synthesis coupled electron transport
K9M52_RS10145	COG3104	oligopeptide transport
K9M52_RS10150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K9M52_RS10165	COG0579	oxidoreductase
K9M52_RS10195	COG0561	phosphatase activity
K9M52_RS10200	COG4771	TonB-dependent receptor
K9M52_RS10205	COG2326	polyphosphate kinase activity
K9M52_RS10210	COG1970	mechanosensitive ion channel activity
K9M52_RS10245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9M52_RS10255	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9M52_RS10260	COG1136	(ABC) transporter
K9M52_RS10265	COG1956	GAF domain-containing protein
K9M52_RS10270	COG3279	Response regulator of the LytR AlgR family
K9M52_RS10275	COG3275	phosphorelay sensor kinase activity
K9M52_RS10280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K9M52_RS10285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K9M52_RS10290	COG3876	Protein conserved in bacteria
K9M52_RS10305	COG1418	mRNA catabolic process
K9M52_RS10310	COG1217	gtp-binding protein TYPA
K9M52_RS10320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K9M52_RS10325	COG0233	cytoplasmic translational termination
K9M52_RS10330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K9M52_RS10335	COG0126	phosphoglycerate kinase activity
K9M52_RS10355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K9M52_RS10355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9M52_RS10365	COG1214	PFAM Peptidase M22, glycoprotease
K9M52_RS10370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K9M52_RS10380	COG0437	4 iron, 4 sulfur cluster binding
K9M52_RS10405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K9M52_RS10410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K9M52_RS10415	COG0109	protoheme IX farnesyltransferase activity
K9M52_RS10425	COG1845	cytochrome c oxidase, subunit III
K9M52_RS10435	COG1999	signal sequence binding
K9M52_RS10440	COG2322	membrane
K9M52_RS10445	COG3118	belongs to the thioredoxin family
K9M52_RS10450	COG0463	Glycosyl transferase, family 2
K9M52_RS10455	COG2176	DNA-directed DNA polymerase activity
K9M52_RS10460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K9M52_RS10475	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K9M52_RS10500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9M52_RS10505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9M52_RS10515	COG1301	dicarboxylic acid transport
K9M52_RS10525	COG0358	DNA primase activity
K9M52_RS10530	COG2363	Small membrane protein
K9M52_RS10535	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K9M52_RS10540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K9M52_RS10550	COG0497	DNA recombination
K9M52_RS10565	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K9M52_RS10570	COG0702	epimerase
K9M52_RS10580	COG0017	Asparaginyl-tRNA synthetase
K9M52_RS10630	COG2814	Major facilitator Superfamily
K9M52_RS10635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K9M52_RS10645	COG1733	regulation of RNA biosynthetic process
K9M52_RS10650	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS10665	COG1764	response to oxidative stress
K9M52_RS10685	COG3279	Response regulator of the LytR AlgR family
K9M52_RS10690	COG0596	Alpha beta hydrolase
K9M52_RS10700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K9M52_RS10715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K9M52_RS10720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K9M52_RS10725	COG0772	Belongs to the SEDS family
K9M52_RS10730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K9M52_RS10735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K9M52_RS10740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K9M52_RS10745	COG0768	penicillin binding
K9M52_RS10755	COG0275	rRNA processing
K9M52_RS10760	COG2001	Belongs to the MraZ family
K9M52_RS10765	COG1733	regulation of RNA biosynthetic process
K9M52_RS10795	COG1940	carbohydrate kinase activity
K9M52_RS10800	COG1629	transport
K9M52_RS10810	COG0673	inositol 2-dehydrogenase activity
K9M52_RS10830	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K9M52_RS10850	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K9M52_RS10880	COG0051	transcription antitermination factor activity, RNA binding
K9M52_RS10885	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K9M52_RS10890	COG0088	Forms part of the polypeptide exit tunnel
K9M52_RS10895	COG0089	rRNA binding
K9M52_RS10900	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K9M52_RS10905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K9M52_RS10910	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K9M52_RS10915	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K9M52_RS10920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K9M52_RS10925	COG0255	Belongs to the universal ribosomal protein uL29 family
K9M52_RS10930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K9M52_RS10935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K9M52_RS10940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K9M52_RS10945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K9M52_RS10950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K9M52_RS10955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K9M52_RS10960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K9M52_RS10965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K9M52_RS10970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K9M52_RS10975	COG1841	ribosomal large subunit assembly
K9M52_RS10980	COG0200	Binds to the 23S rRNA
K9M52_RS10995	COG2081	HI0933 family
K9M52_RS11020	COG1349	DNA-binding transcription factor activity
K9M52_RS11030	COG3959	Transketolase, thiamine diphosphate binding domain
K9M52_RS11035	COG3958	Transketolase
K9M52_RS11050	COG1129	ABC transporter
K9M52_RS11055	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9M52_RS11060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K9M52_RS11065	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K9M52_RS11065	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K9M52_RS11075	COG0714	Associated with various cellular activities
K9M52_RS11120	COG0321	lipoyl(octanoyl) transferase activity
K9M52_RS11125	COG4206	TonB-dependent receptor
K9M52_RS11135	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K9M52_RS11145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9M52_RS11145	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K9M52_RS11160	COG0006	proline dipeptidase activity
K9M52_RS11165	COG1183	phosphatidylcholine synthase activity
K9M52_RS11170	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K9M52_RS11180	COG1162	GTPase activity
K9M52_RS11190	COG1138	Cytochrome C-type biogenesis protein
K9M52_RS11200	COG3345	alpha-galactosidase
K9M52_RS11210	COG0745	RESPONSE REGULATOR receiver
K9M52_RS11210	COG3292	Two component regulator propeller
K9M52_RS11210	COG2205	protein histidine kinase activity
K9M52_RS11225	COG1629	transport
K9M52_RS11240	COG3250	beta-galactosidase activity
K9M52_RS11245	COG4771	TonB-dependent receptor
K9M52_RS11255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9M52_RS11265	COG0564	pseudouridine synthase activity
K9M52_RS11270	COG1047	Peptidyl-prolyl cis-trans
K9M52_RS11275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS11280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9M52_RS11295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K9M52_RS11300	COG1556	Lactate utilization protein
K9M52_RS11305	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9M52_RS11315	COG0668	transmembrane transport
K9M52_RS11325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K9M52_RS11345	COG0616	signal peptide processing
K9M52_RS11350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K9M52_RS11355	COG0805	protein transport
K9M52_RS11360	COG0604	alcohol dehydrogenase
K9M52_RS11395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K9M52_RS11415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS11420	COG2204	response regulator
K9M52_RS11425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K9M52_RS11435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K9M52_RS11445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K9M52_RS11450	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9M52_RS11470	COG0724	RNA recognition motif
K9M52_RS11475	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K9M52_RS11480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K9M52_RS11485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K9M52_RS11485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K9M52_RS11490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K9M52_RS11505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K9M52_RS11520	COG3186	Phenylalanine-4-hydroxylase
K9M52_RS11525	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K9M52_RS11545	COG1131	(ABC) transporter
K9M52_RS11560	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K9M52_RS11610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K9M52_RS11615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K9M52_RS11625	COG1482	cell wall glycoprotein biosynthetic process
K9M52_RS11635	COG4974	Belongs to the 'phage' integrase family
K9M52_RS11640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K9M52_RS11645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K9M52_RS11650	COG0149	triose-phosphate isomerase activity
K9M52_RS11670	COG0322	excinuclease ABC activity
K9M52_RS11680	COG1331	Highly conserved protein containing a thioredoxin domain
K9M52_RS11690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K9M52_RS11700	COG1999	signal sequence binding
K9M52_RS11710	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
K9M52_RS11725	COG1063	alcohol dehydrogenase
K9M52_RS11745	COG4771	TonB-dependent receptor
K9M52_RS11755	COG1629	transport
K9M52_RS11755	COG4206	TonB-dependent receptor
K9M52_RS11805	COG3325	Belongs to the glycosyl hydrolase 18 family
K9M52_RS11805	COG3469	chitinase activity
K9M52_RS11900	COG4771	TonB-dependent receptor
K9M52_RS11910	COG2207	Transcriptional regulator
K9M52_RS11910	COG0662	Cupin 2, conserved barrel domain protein
K9M52_RS11930	COG2010	Cytochrome c
K9M52_RS11945	COG4771	TonB-dependent receptor
K9M52_RS11950	COG0702	epimerase
K9M52_RS11975	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K9M52_RS12005	COG3119	arylsulfatase activity
K9M52_RS12015	COG1629	transport
K9M52_RS12030	COG0577	efflux transmembrane transporter activity
K9M52_RS12035	COG0640	Transcriptional regulator
K9M52_RS12050	COG3486	L-lysine 6-monooxygenase (NADPH) activity
K9M52_RS12085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K9M52_RS12095	COG0251	oxidation-reduction process
K9M52_RS12130	COG3345	alpha-galactosidase
K9M52_RS12135	COG0339	signal peptide processing
K9M52_RS12150	COG2706	6-phosphogluconolactonase activity
K9M52_RS12170	COG0702	epimerase
K9M52_RS12185	COG1629	transport
K9M52_RS12190	COG0702	epimerase
K9M52_RS12210	COG0657	acetylesterase activity
K9M52_RS12215	COG1619	proteins homologs of microcin C7 resistance protein MccF
K9M52_RS12220	COG1619	proteins homologs of microcin C7 resistance protein MccF
K9M52_RS12250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K9M52_RS12255	COG0632	four-way junction helicase activity
K9M52_RS12265	COG0697	spore germination
K9M52_RS12275	COG2197	response regulator
K9M52_RS12290	COG1522	sequence-specific DNA binding
K9M52_RS12310	COG0668	transmembrane transport
K9M52_RS12315	COG0556	nucleotide-excision repair
K9M52_RS12325	COG3852	Histidine kinase
K9M52_RS12335	COG0175	sulfate reduction
K9M52_RS12340	COG0175	sulfate reduction
K9M52_RS12350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K9M52_RS12350	COG1648	precorrin-2 dehydrogenase activity
K9M52_RS12365	COG0730	response to heat
K9M52_RS12375	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K9M52_RS12380	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K9M52_RS12385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K9M52_RS12390	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K9M52_RS12395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K9M52_RS12400	COG0202	RNA polymerase activity
K9M52_RS12405	COG0203	ribosomal protein L17
K9M52_RS12420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K9M52_RS12425	COG0423	glycine-tRNA ligase activity
K9M52_RS12430	COG1704	LemA family
K9M52_RS12455	COG0512	Glutamine amidotransferase of anthranilate synthase
K9M52_RS12460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K9M52_RS12465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K9M52_RS12520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K9M52_RS12520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
K9M52_RS12525	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9M52_RS12530	COG1078	dGTPase activity
K9M52_RS12535	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K9M52_RS12555	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K9M52_RS12565	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K9M52_RS12570	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K9M52_RS12575	COG0511	ligase activity, forming carbon-carbon bonds
K9M52_RS12580	COG0439	Biotin carboxylase
K9M52_RS12610	COG0071	Belongs to the small heat shock protein (HSP20) family
K9M52_RS12620	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
K9M52_RS12655	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K9M52_RS12665	COG3304	Inner membrane component domain
K9M52_RS12670	COG3250	beta-galactosidase activity
K9M52_RS12685	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
K9M52_RS12705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K9M52_RS12710	COG0702	epimerase
K9M52_RS12715	COG1194	a g-specific adenine glycosylase
K9M52_RS12735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K9M52_RS12745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9M52_RS12755	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K9M52_RS12770	COG0545	Peptidyl-prolyl cis-trans isomerase
K9M52_RS12775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K9M52_RS12780	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9M52_RS12785	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9M52_RS12785	COG0567	Dehydrogenase, E1 component
K9M52_RS12790	COG0268	Binds directly to 16S ribosomal RNA
K9M52_RS12800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K9M52_RS12800	COG0519	Catalyzes the synthesis of GMP from XMP
K9M52_RS12870	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
K9M52_RS12885	COG0673	inositol 2-dehydrogenase activity
K9M52_RS12895	COG0523	cobalamin synthesis protein
K9M52_RS12905	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
K9M52_RS12910	COG1522	sequence-specific DNA binding
K9M52_RS12915	COG2149	membrane
K9M52_RS12925	COG0431	NADPH-dependent FMN reductase
K9M52_RS12990	COG0366	Alpha amylase catalytic
K9M52_RS13015	COG0583	DNA-binding transcription factor activity
K9M52_RS13020	COG2855	membrane
K9M52_RS13025	COG2084	Dehydrogenase
K9M52_RS13035	COG2986	histidine ammonia-lyase
K9M52_RS13040	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K9M52_RS13050	COG0010	Belongs to the arginase family
K9M52_RS13060	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K9M52_RS13070	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9M52_RS13090	COG2154	pterin-4-alpha-carbinolamine dehydratase
K9M52_RS13095	COG0589	response to stress
K9M52_RS13115	COG0561	phosphatase activity
K9M52_RS13120	COG1629	transport
K9M52_RS13135	COG0321	lipoyl(octanoyl) transferase activity
K9M52_RS13135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K9M52_RS13150	COG2027	D-alanyl-D-alanine carboxypeptidase
K9M52_RS13155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K9M52_RS13160	COG1959	2 iron, 2 sulfur cluster binding
K9M52_RS13170	COG0860	N-Acetylmuramoyl-L-alanine amidase
K9M52_RS13185	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K9M52_RS13205	COG0714	Associated with various cellular activities
K9M52_RS13210	COG2226	methyltransferase
K9M52_RS13225	COG1132	(ABC) transporter
K9M52_RS13230	COG4221	oxidoreductase activity
K9M52_RS13240	COG2321	neutral zinc metallopeptidase
K9M52_RS13245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K9M52_RS13250	COG0193	aminoacyl-tRNA hydrolase activity
K9M52_RS13255	COG1289	transmembrane transporter activity
K9M52_RS13260	COG0194	GDP metabolic process
K9M52_RS13265	COG0778	Nitroreductase
K9M52_RS13270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K9M52_RS13280	COG2133	pyrroloquinoline quinone binding
K9M52_RS13295	COG0284	orotidine-5'-phosphate decarboxylase activity
K9M52_RS13330	COG0505	Belongs to the CarA family
K9M52_RS13340	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9M52_RS13345	COG1058	Belongs to the CinA family
K9M52_RS13345	COG1546	Belongs to the CinA family
K9M52_RS13355	COG2814	Major facilitator Superfamily
K9M52_RS13365	COG0442	prolyl-tRNA aminoacylation
K9M52_RS13380	COG0527	aspartate kinase activity
K9M52_RS13385	COG1131	(ABC) transporter
K9M52_RS13390	COG2318	DinB family
K9M52_RS13405	COG0531	amino acid
K9M52_RS13415	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K9M52_RS13420	COG2204	response regulator
K9M52_RS13435	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
K9M52_RS13440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9M52_RS13465	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K9M52_RS13470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K9M52_RS13470	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
K9M52_RS13480	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
K9M52_RS13485	COG2171	N-acyltransferase activity
K9M52_RS13490	COG0009	L-threonylcarbamoyladenylate synthase
K9M52_RS13500	COG0306	phosphate transporter
K9M52_RS13520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K9M52_RS13525	COG3958	Transketolase
K9M52_RS13530	COG1595	DNA-templated transcription, initiation
K9M52_RS13545	COG0673	inositol 2-dehydrogenase activity
K9M52_RS13555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9M52_RS13575	COG0316	Belongs to the HesB IscA family
K9M52_RS13580	COG0719	Fe-S assembly protein
K9M52_RS13585	COG0396	ATPase activity
K9M52_RS13590	COG0719	Fe-S assembly protein
K9M52_RS13595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K9M52_RS13600	COG2166	iron-sulfur cluster assembly
K9M52_RS13605	COG2151	metal-sulfur cluster biosynthetic enzyme
K9M52_RS13615	COG1609	Transcriptional regulator
K9M52_RS13620	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
K9M52_RS13625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9M52_RS13640	COG0700	Nucleoside recognition
K9M52_RS13650	COG0205	6-phosphofructokinase activity
K9M52_RS13655	COG0469	pyruvate kinase activity
K9M52_RS13665	COG1435	thymidine kinase activity
K9M52_RS13680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K9M52_RS13685	COG0681	Belongs to the peptidase S26 family
K9M52_RS13700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K9M52_RS13710	COG0581	inorganic phosphate transmembrane transporter activity
K9M52_RS13715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K9M52_RS13730	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K9M52_RS13740	COG0738	Major facilitator superfamily
K9M52_RS13745	COG3254	rhamnose metabolic process
K9M52_RS13750	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS13755	COG0179	Fumarylacetoacetate (FAA) hydrolase
K9M52_RS13760	COG3618	amidohydrolase
K9M52_RS13770	COG2721	sulfolactate sulfo-lyase activity
K9M52_RS13775	COG1629	transport
K9M52_RS13790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K9M52_RS13800	COG0012	GTP binding
K9M52_RS13810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9M52_RS13815	COG3119	arylsulfatase activity
K9M52_RS13820	COG1629	transport
K9M52_RS13825	COG0561	phosphatase activity
K9M52_RS13845	COG2755	lipolytic protein G-D-S-L family
K9M52_RS13850	COG4677	pectinesterase activity
K9M52_RS13875	COG2755	lipolytic protein G-D-S-L family
K9M52_RS13895	COG1629	transport
K9M52_RS13900	COG0702	epimerase
K9M52_RS13910	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K9M52_RS13915	COG0246	Mannitol dehydrogenase
K9M52_RS13920	COG2721	sulfolactate sulfo-lyase activity
K9M52_RS13940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K9M52_RS13950	COG4206	TonB-dependent receptor
K9M52_RS13950	COG1629	transport
K9M52_RS13955	COG0702	epimerase
K9M52_RS13990	COG3537	Alpha-1,2-mannosidase
K9M52_RS13995	COG1321	iron dependent repressor
K9M52_RS14005	COG0045	succinate-CoA ligase (ADP-forming) activity
K9M52_RS14010	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K9M52_RS14015	COG0538	isocitrate dehydrogenase activity
K9M52_RS14025	COG0285	dihydrofolate synthase activity
K9M52_RS14030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K9M52_RS14050	COG1132	(ABC) transporter
K9M52_RS14075	COG1649	PFAM Uncharacterised BCR, COG1649
K9M52_RS14095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9M52_RS14100	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
K9M52_RS14105	COG0247	lactate metabolic process
K9M52_RS14105	COG2181	nitrate reductase activity
K9M52_RS14110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9M52_RS14115	COG3023	N-Acetylmuramoyl-L-alanine amidase
K9M52_RS14120	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K9M52_RS14130	COG1940	carbohydrate kinase activity
K9M52_RS14155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K9M52_RS14160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K9M52_RS14165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K9M52_RS14170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K9M52_RS14185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K9M52_RS14190	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K9M52_RS14195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K9M52_RS14200	COG0653	protein targeting
K9M52_RS14210	COG1476	TRANSCRIPTIONal
K9M52_RS14225	COG2378	regulation of single-species biofilm formation
K9M52_RS14230	COG1668	transmembrane transport
K9M52_RS14235	COG4152	abc transporter atp-binding protein
K9M52_RS14240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K9M52_RS14245	COG1611	Belongs to the LOG family
K9M52_RS14250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K9M52_RS14255	COG0482	sulfurtransferase activity
K9M52_RS14275	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
K9M52_RS14280	COG3047	cAMP biosynthetic process
K9M52_RS14280	COG2885	chlorophyll binding
K9M52_RS14315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K9M52_RS14320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K9M52_RS14325	COG1739	Uncharacterized protein family UPF0029
K9M52_RS14340	COG1381	Involved in DNA repair and RecF pathway recombination
K9M52_RS14350	COG0527	aspartate kinase activity
K9M52_RS14380	COG0662	Cupin 2, conserved barrel domain protein
K9M52_RS14380	COG2207	Transcriptional regulator
K9M52_RS14415	COG2239	Acts as a magnesium transporter
K9M52_RS14435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K9M52_RS14455	COG2176	DNA-directed DNA polymerase activity
K9M52_RS14465	COG0540	Belongs to the ATCase OTCase family
K9M52_RS14470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K9M52_RS14515	COG1064	alcohol dehydrogenase
K9M52_RS14530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K9M52_RS14545	COG0148	phosphopyruvate hydratase activity
K9M52_RS14555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K9M52_RS14575	COG0436	Aminotransferase
K9M52_RS14580	COG0287	Prephenate dehydrogenase
K9M52_RS14585	COG0513	Belongs to the DEAD box helicase family
K9M52_RS14590	COG2877	3-deoxy-8-phosphooctulonate synthase activity
K9M52_RS14610	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K9M52_RS14615	COG3590	peptidase
K9M52_RS14625	COG0531	amino acid
K9M52_RS14635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K9M52_RS14645	COG1252	NADH dehydrogenase
K9M52_RS14685	COG0671	phosphoesterase, PA-phosphatase related
K9M52_RS14690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K9M52_RS14705	COG0107	imidazoleglycerol-phosphate synthase activity
K9M52_RS14710	COG0140	phosphoribosyl-ATP diphosphatase activity
K9M52_RS14710	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K9M52_RS14715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS14720	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K9M52_RS14725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K9M52_RS14730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K9M52_RS14750	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K9M52_RS14755	COG0628	permease
K9M52_RS14765	COG1215	transferase activity, transferring glycosyl groups
K9M52_RS14770	COG2151	metal-sulfur cluster biosynthetic enzyme
K9M52_RS14790	COG0010	Belongs to the arginase family
K9M52_RS14805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K9M52_RS14810	COG4771	TonB-dependent receptor
K9M52_RS14815	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9M52_RS14825	COG0166	Belongs to the GPI family
K9M52_RS14830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K9M52_RS14835	COG1968	undecaprenyl-diphosphatase activity
K9M52_RS14840	COG2270	Major facilitator Superfamily
K9M52_RS14845	COG2226	methyltransferase
K9M52_RS14870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K9M52_RS14870	COG1648	precorrin-2 dehydrogenase activity
K9M52_RS14875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9M52_RS14885	COG0243	molybdopterin cofactor binding
K9M52_RS14910	COG0539	negative regulation of cytoplasmic translation
K9M52_RS14910	COG2183	response to ionizing radiation
K9M52_RS14920	COG1166	arginine decarboxylase activity
K9M52_RS14925	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K9M52_RS14930	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K9M52_RS14935	COG0038	chloride channel
K9M52_RS14940	COG1054	Belongs to the UPF0176 family
K9M52_RS14965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K9M52_RS14975	COG0037	tRNA processing
K9M52_RS14985	COG1012	belongs to the aldehyde dehydrogenase family
K9M52_RS14990	COG0022	dehydrogenase e1 component
K9M52_RS14990	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9M52_RS15015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K9M52_RS15025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K9M52_RS15045	COG0346	lactoylglutathione lyase activity
K9M52_RS15050	COG0706	membrane insertase activity
K9M52_RS15060	COG1051	belongs to the nudix hydrolase family
K9M52_RS15070	COG2195	Cleaves the N-terminal amino acid of tripeptides
K9M52_RS15080	COG1396	sequence-specific DNA binding
K9M52_RS15085	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K9M52_RS15095	COG2989	Protein conserved in bacteria
K9M52_RS15100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K9M52_RS15105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K9M52_RS15110	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K9M52_RS15120	COG0842	Transport permease protein
K9M52_RS15120	COG1129	ABC transporter
K9M52_RS15125	COG0842	Transport permease protein
K9M52_RS15130	COG1131	(ABC) transporter
K9M52_RS15135	COG1131	(ABC) transporter
K9M52_RS15140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9M52_RS15155	COG3250	beta-galactosidase activity
K9M52_RS15165	COG1051	belongs to the nudix hydrolase family
K9M52_RS15170	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K9M52_RS15175	COG0552	protein localization to endoplasmic reticulum
K9M52_RS15360	COG1629	transport
K9M52_RS15370	COG0300	oxidoreductase activity
K9M52_RS15375	COG0412	Dienelactone hydrolase
K9M52_RS15380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K9M52_RS15390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K9M52_RS15395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K9M52_RS15400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K9M52_RS15425	COG3279	Response regulator of the LytR AlgR family
K9M52_RS15430	COG3275	phosphorelay sensor kinase activity
K9M52_RS15435	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K9M52_RS15440	COG1674	ftsk spoiiie
K9M52_RS15445	COG1607	acyl-coa hydrolase
K9M52_RS15460	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K9M52_RS15475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9M52_RS15480	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K9M52_RS15485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K9M52_RS15490	COG0159	tryptophan synthase activity
K9M52_RS15495	COG0133	tryptophan synthase activity
K9M52_RS15505	COG0135	phosphoribosylanthranilate isomerase activity
K9M52_RS15510	COG0134	indole-3-glycerol-phosphate synthase activity
K9M52_RS15515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K9M52_RS15520	COG0512	Glutamine amidotransferase of anthranilate synthase
K9M52_RS15520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K9M52_RS15525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K9M52_RS15535	COG0564	pseudouridine synthase activity
K9M52_RS15540	COG1187	pseudouridine synthase activity
K9M52_RS15545	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K9M52_RS15555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K9M52_RS15565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K9M52_RS15570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K9M52_RS15575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K9M52_RS15580	COG2045	Belongs to the ComB family
K9M52_RS15610	COG1472	Belongs to the glycosyl hydrolase 3 family
K9M52_RS15615	COG1595	DNA-templated transcription, initiation
K9M52_RS15620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K9M52_RS15630	COG0531	amino acid
K9M52_RS15640	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K9M52_RS15640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K9M52_RS15650	COG3459	Glycosyltransferase 36 associated
K9M52_RS15655	COG2211	Major facilitator Superfamily
K9M52_RS15665	COG0514	ATP-dependent DNA helicase (RecQ)
K9M52_RS15670	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K9M52_RS15670	COG0517	IMP dehydrogenase activity
K9M52_RS15700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K9M52_RS15710	COG0823	Involved in the tonB-independent uptake of proteins
K9M52_RS15710	COG1506	peptidase
K9M52_RS15720	COG0528	UMP kinase activity
K9M52_RS15730	COG0067	glutamate synthase
K9M52_RS15730	COG0069	glutamate synthase activity
K9M52_RS15730	COG0070	glutamate synthase
K9M52_RS15735	COG0386	Belongs to the glutathione peroxidase family
K9M52_RS15745	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9M52_RS15745	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9M52_RS15755	COG1309	transcriptional regulator
K9M52_RS15770	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS15795	COG0667	Aldo Keto reductase
K9M52_RS15810	COG1446	asparaginase
K9M52_RS15840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K9M52_RS15850	COG0745	RESPONSE REGULATOR receiver
K9M52_RS15850	COG2205	protein histidine kinase activity
K9M52_RS15850	COG3292	Two component regulator propeller
K9M52_RS15855	COG0745	RESPONSE REGULATOR receiver
K9M52_RS15855	COG2205	protein histidine kinase activity
K9M52_RS15855	COG3292	Two component regulator propeller
K9M52_RS15885	COG1196	nuclear chromosome segregation
K9M52_RS15890	COG0484	heat shock protein binding
K9M52_RS15900	COG0545	Peptidyl-prolyl cis-trans isomerase
K9M52_RS15910	COG0124	histidyl-tRNA synthetase
K9M52_RS15915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K9M52_RS15930	COG0131	Imidazoleglycerol-phosphate dehydratase
K9M52_RS15935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K9M52_RS15945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K9M52_RS15965	COG1764	response to oxidative stress
K9M52_RS15970	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
K9M52_RS15980	COG0667	Aldo Keto reductase
K9M52_RS15985	COG2255	four-way junction helicase activity
K9M52_RS15995	COG0254	rRNA binding
K9M52_RS16000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K9M52_RS16015	COG0544	peptidyl-prolyl cis-trans isomerase activity
K9M52_RS16030	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K9M52_RS16050	COG4771	TonB-dependent receptor
K9M52_RS16060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K9M52_RS16065	COG0667	Aldo Keto reductase
K9M52_RS16070	COG3250	beta-galactosidase activity
K9M52_RS16080	COG2814	Major facilitator Superfamily
K9M52_RS16085	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K9M52_RS16095	COG0489	protein tyrosine kinase activity
K9M52_RS16105	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K9M52_RS16140	COG0191	fructose-bisphosphate aldolase activity
K9M52_RS16150	COG0601	transmembrane transport
K9M52_RS16185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K9M52_RS16205	COG0492	ferredoxin-NADP+ reductase activity
K9M52_RS16210	COG0280	phosphate acetyltransferase
K9M52_RS16210	COG0281	malic enzyme
K9M52_RS16215	COG1473	amidohydrolase
K9M52_RS16220	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K9M52_RS16225	COG0023	Translation Initiation Factor
K9M52_RS16235	COG1940	carbohydrate kinase activity
K9M52_RS16255	COG0488	(ABC) transporter
K9M52_RS16260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K9M52_RS16275	COG1765	OsmC-like protein
K9M52_RS16290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K9M52_RS16295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K9M52_RS16300	COG0066	3-isopropylmalate dehydratase activity
K9M52_RS16305	COG2226	methyltransferase
K9M52_RS16310	COG1119	ATPase activity
K9M52_RS16315	COG0473	3-isopropylmalate dehydrogenase activity
K9M52_RS16325	COG0028	Belongs to the TPP enzyme family
K9M52_RS16340	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K9M52_RS16345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K9M52_RS16350	COG0110	maltose O-acetyltransferase activity
K9M52_RS16365	COG1408	metallophosphoesterase
K9M52_RS16370	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K9M52_RS16375	COG1192	Involved in chromosome partitioning
K9M52_RS16380	COG1475	DNA binding
K9M52_RS16390	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K9M52_RS16395	COG0277	FAD linked oxidase domain protein
K9M52_RS16405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K9M52_RS16410	COG1388	LysM domain
K9M52_RS16410	COG1705	Flagellar rod assembly protein muramidase FlgJ
K9M52_RS16420	COG4145	pantothenate transmembrane transporter activity
K9M52_RS16425	COG2153	protein acetylation
K9M52_RS16430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K9M52_RS16435	COG0156	8-amino-7-oxononanoate synthase activity
K9M52_RS16445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K9M52_RS16475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9M52_RS16510	COG0488	(ABC) transporter
K9M52_RS16515	COG1584	GPR1 FUN34 yaaH family protein
K9M52_RS16520	COG0519	Catalyzes the synthesis of GMP from XMP
K9M52_RS16525	COG0363	glucosamine-6-phosphate deaminase activity
K9M52_RS16535	COG1271	oxidase subunit
K9M52_RS16540	COG0436	Aminotransferase
K9M52_RS16545	COG0463	Glycosyl transferase, family 2
K9M52_RS16555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K9M52_RS16560	COG1104	cysteine desulfurase activity
K9M52_RS16565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9M52_RS16585	COG0488	(ABC) transporter
K9M52_RS16590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9M52_RS16605	COG4172	Belongs to the ABC transporter superfamily
K9M52_RS16610	COG1132	(ABC) transporter
K9M52_RS16615	COG0506	proline dehydrogenase activity
K9M52_RS16630	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K9M52_RS16645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K9M52_RS16665	COG0596	Alpha beta hydrolase
K9M52_RS16675	COG2267	carboxylic ester hydrolase activity
K9M52_RS16680	COG2169	Transcriptional regulator
K9M52_RS16690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K9M52_RS16710	COG0667	Aldo Keto reductase
K9M52_RS16740	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS16750	COG0494	nUDIX hydrolase
K9M52_RS16755	COG0693	protein deglycase activity
K9M52_RS16760	COG0475	glutathione-regulated potassium exporter activity
K9M52_RS16760	COG0589	response to stress
K9M52_RS16775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K9M52_RS16795	COG1595	DNA-templated transcription, initiation
K9M52_RS16800	COG1064	alcohol dehydrogenase
K9M52_RS16840	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
K9M52_RS16850	COG2259	Doxx family
K9M52_RS16860	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K9M52_RS16880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K9M52_RS16885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K9M52_RS16890	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
K9M52_RS16900	COG1472	Belongs to the glycosyl hydrolase 3 family
K9M52_RS16905	COG1940	carbohydrate kinase activity
K9M52_RS16910	COG4206	TonB-dependent receptor
K9M52_RS16910	COG1629	transport
K9M52_RS16920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K9M52_RS16925	COG0167	dihydroorotate dehydrogenase activity
K9M52_RS16935	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K9M52_RS16940	COG0756	dUTP diphosphatase activity
K9M52_RS16970	COG0492	ferredoxin-NADP+ reductase activity
K9M52_RS16980	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9M52_RS17005	COG1640	4-alpha-glucanotransferase
K9M52_RS17020	COG0626	cystathionine gamma-synthase activity
K9M52_RS17030	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
K9M52_RS17060	COG1733	regulation of RNA biosynthetic process
K9M52_RS17065	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS17070	COG0673	inositol 2-dehydrogenase activity
K9M52_RS17080	COG1363	Peptidase, m42
K9M52_RS17100	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K9M52_RS17110	COG3189	MarR family transcriptional regulator
K9M52_RS17125	COG2346	COG2346, Truncated hemoglobins
K9M52_RS17145	COG2010	Cytochrome c
K9M52_RS17155	COG1959	2 iron, 2 sulfur cluster binding
K9M52_RS17165	COG0450	alkyl hydroperoxide reductase
K9M52_RS17170	COG0668	transmembrane transport
K9M52_RS17190	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K9M52_RS17225	COG2197	response regulator
K9M52_RS17240	COG2267	carboxylic ester hydrolase activity
K9M52_RS17245	COG1132	(ABC) transporter
K9M52_RS17250	COG1132	(ABC) transporter
K9M52_RS17255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K9M52_RS17265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K9M52_RS17270	COG0247	lactate metabolic process
K9M52_RS17300	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K9M52_RS17305	COG0105	UTP biosynthetic process
K9M52_RS17310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K9M52_RS17325	COG1629	transport
K9M52_RS17330	COG0702	epimerase
K9M52_RS17340	COG1472	Belongs to the glycosyl hydrolase 3 family
K9M52_RS17345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K9M52_RS17350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K9M52_RS17355	COG1393	Belongs to the ArsC family
K9M52_RS17360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K9M52_RS17370	COG1862	Preprotein translocase
K9M52_RS17375	COG0237	dephospho-CoA kinase activity
K9M52_RS17390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K9M52_RS17390	COG1796	DNA polymerase
K9M52_RS17395	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K9M52_RS17400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K9M52_RS17405	COG0363	glucosamine-6-phosphate deaminase activity
K9M52_RS17415	COG1053	succinate dehydrogenase
K9M52_RS17420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K9M52_RS17430	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K9M52_RS17435	COG4974	Belongs to the 'phage' integrase family
K9M52_RS17440	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K9M52_RS17455	COG1253	flavin adenine dinucleotide binding
K9M52_RS17465	COG0617	tRNA 3'-terminal CCA addition
K9M52_RS17480	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
K9M52_RS17490	COG2733	membrane
K9M52_RS17495	COG2814	Major facilitator Superfamily
K9M52_RS17510	COG1309	transcriptional regulator
K9M52_RS17515	COG3956	TIGRFAM MazG family protein
K9M52_RS17520	COG5000	phosphorelay sensor kinase activity
K9M52_RS17535	COG0252	asparaginase activity
K9M52_RS17540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9M52_RS17545	COG3590	peptidase
K9M52_RS17565	COG4771	TonB-dependent receptor
K9M52_RS17575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS17580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS17585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9M52_RS17590	COG0825	malonyl-CoA metabolic process
K9M52_RS17620	COG2814	Major facilitator Superfamily
K9M52_RS17640	COG0513	Belongs to the DEAD box helicase family
K9M52_RS17650	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K9M52_RS17660	COG3250	beta-galactosidase activity
K9M52_RS17670	COG2176	DNA-directed DNA polymerase activity
K9M52_RS17685	COG0577	efflux transmembrane transporter activity
K9M52_RS17685	COG1136	(ABC) transporter
K9M52_RS17695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K9M52_RS17710	COG0018	arginyl-trna synthetase
K9M52_RS17715	COG0156	8-amino-7-oxononanoate synthase activity
K9M52_RS17720	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K9M52_RS17725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K9M52_RS17730	COG0242	peptide deformylase activity
K9M52_RS17740	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
K9M52_RS17750	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
K9M52_RS17760	COG1629	transport
K9M52_RS17795	COG4771	TonB-dependent receptor
K9M52_RS17845	COG4771	TonB-dependent receptor
K9M52_RS17870	COG0156	8-amino-7-oxononanoate synthase activity
K9M52_RS17880	COG0488	(ABC) transporter
K9M52_RS17885	COG2885	chlorophyll binding
K9M52_RS17900	COG3250	beta-galactosidase activity
K9M52_RS17910	COG1570	exodeoxyribonuclease VII activity
K9M52_RS17930	COG3250	beta-galactosidase activity
K9M52_RS17935	COG1629	transport
K9M52_RS17935	COG4206	TonB-dependent receptor
K9M52_RS17940	COG0702	epimerase
K9M52_RS17945	COG1073	alpha beta
K9M52_RS17960	COG0596	Alpha beta hydrolase
K9M52_RS17965	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS17975	COG1028	Short-chain dehydrogenase reductase Sdr
K9M52_RS17980	COG1733	regulation of RNA biosynthetic process
K9M52_RS17990	COG4771	TonB-dependent receptor
K9M52_RS17995	COG4948	Mandelate Racemase Muconate Lactonizing
K9M52_RS18000	COG3537	Alpha-1,2-mannosidase
K9M52_RS18010	COG4771	TonB-dependent receptor
K9M52_RS18015	COG0702	epimerase
K9M52_RS18020	COG1629	transport
K9M52_RS18035	COG0702	epimerase
K9M52_RS18060	COG3537	Alpha-1,2-mannosidase
K9M52_RS18075	COG0738	Major facilitator superfamily
K9M52_RS18080	COG1609	Transcriptional regulator
K9M52_RS18110	COG1120	ATPase activity
K9M52_RS18115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K9M52_RS18120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9M52_RS18155	COG0745	RESPONSE REGULATOR receiver
K9M52_RS18160	COG5002	protein histidine kinase activity
K9M52_RS18200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K9M52_RS18205	COG1252	NADH dehydrogenase
K9M52_RS18215	COG3604	Transcriptional regulator
K9M52_RS18225	COG1725	Transcriptional regulator
K9M52_RS18235	COG1131	(ABC) transporter
K9M52_RS18240	COG2223	nitrite transmembrane transporter activity
K9M52_RS18245	COG2186	Transcriptional regulator
K9M52_RS18250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K9M52_RS18275	COG3250	beta-galactosidase activity
K9M52_RS18335	COG1629	transport
K9M52_RS18360	COG1629	transport
K9M52_RS18370	COG3511	phospholipase C
K9M52_RS18380	COG0657	acetylesterase activity
K9M52_RS18380	COG2755	lipolytic protein G-D-S-L family
K9M52_RS18385	COG3119	arylsulfatase activity
K9M52_RS18390	COG0702	epimerase
K9M52_RS18395	COG1629	transport
K9M52_RS18400	COG0667	Aldo Keto reductase
K9M52_RS18405	COG0405	Gamma-glutamyltransferase
K9M52_RS18410	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
K9M52_RS18425	COG0702	epimerase
K9M52_RS18430	COG1629	transport
K9M52_RS18455	COG0798	PFAM Bile acid sodium symporter
K9M52_RS18460	COG2226	methyltransferase
K9M52_RS18465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K9M52_RS18470	COG0640	Transcriptional regulator
K9M52_RS18485	COG2267	carboxylic ester hydrolase activity
K9M52_RS18500	COG4771	TonB-dependent receptor
K9M52_RS18520	COG0577	efflux transmembrane transporter activity
K9M52_RS18530	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K9M52_RS18535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9M52_RS18540	COG0477	Major facilitator Superfamily
K9M52_RS18545	COG2217	Heavy metal translocating P-type atpase
K9M52_RS18555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9M52_RS18580	COG3158	transport of potassium into the cell
K9M52_RS18585	COG0668	transmembrane transport
K9M52_RS18610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS18615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9M52_RS18620	COG0793	Belongs to the peptidase S41A family
K9M52_RS18635	COG1629	transport
K9M52_RS18635	COG4206	TonB-dependent receptor
K9M52_RS18645	COG1595	DNA-templated transcription, initiation
K9M52_RS18705	COG0702	epimerase
K9M52_RS18755	COG0587	DNA-directed DNA polymerase activity
K9M52_RS18760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K9M52_RS18785	COG3550	peptidyl-serine autophosphorylation
K9M52_RS18825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K9M52_RS18830	COG1733	regulation of RNA biosynthetic process
K9M52_RS18850	COG4771	TonB-dependent receptor
K9M52_RS18855	COG1846	Transcriptional regulator
K9M52_RS18855	COG1940	carbohydrate kinase activity
K9M52_RS18865	COG3604	Transcriptional regulator
K9M52_RS18870	COG0071	Belongs to the small heat shock protein (HSP20) family
K9M52_RS18885	COG0456	acetyltransferase
K9M52_RS18915	COG4974	Belongs to the 'phage' integrase family
K9M52_RS18920	COG4974	Belongs to the 'phage' integrase family
K9M52_RS18925	COG4974	Belongs to the 'phage' integrase family
K9M52_RS18950	COG0297	glycogen (starch) synthase activity
K9M52_RS18950	COG0438	transferase activity, transferring glycosyl groups
K9M52_RS18965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K9M52_RS18985	COG3328	transposase activity