locus-tag	class	description
H2O17_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
H2O17_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
H2O17_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
H2O17_RS00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H2O17_RS00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H2O17_RS00035	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
H2O17_RS00080	ENOG4105VPX	protein, conserved in bacteria
H2O17_RS00100	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H2O17_RS00110	ENOG4105DEF	Extracellular solute-binding protein, family 5
H2O17_RS00115	ENOG4105CI2	imidazolone-5-propionate hydrolase
H2O17_RS00145	ENOG4105CPC	Aldo Keto reductase
H2O17_RS00160	ENOG4108RYK	Nad-dependent epimerase dehydratase
H2O17_RS00165	ENOG4105DQ4	alcohol dehydrogenase
H2O17_RS00170	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
H2O17_RS00190	ENOG4105ZJT	Cell division protein CrgA
H2O17_RS00195	ENOG4108U4N	(sortase) family
H2O17_RS00205	ENOG4105D9P	serine threonine protein kinase
H2O17_RS00210	ENOG4105CJN	penicillin-binding protein
H2O17_RS00225	ENOG4105HZM	Fha domain containing protein
H2O17_RS00230	ENOG4105IDI	abc transporter atp-binding protein
H2O17_RS00245	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H2O17_RS00250	ENOG4105BZ1	(ABC) transporter
H2O17_RS00255	ENOG4105BZ1	(ABC) transporter
H2O17_RS00260	ENOG4108UVJ	appr-1-p processing domain protein
H2O17_RS00275	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
H2O17_RS00280	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
H2O17_RS00295	ENOG4107QI1	Mate efflux family protein
H2O17_RS00300	ENOG4105CDU	Replicative dna helicase
H2O17_RS00305	ENOG4105DWF	phosphomethylpyrimidine kinase
H2O17_RS00345	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
H2O17_RS00385	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H2O17_RS00395	ENOG4105WH1	Two component transcriptional regulator luxr family
H2O17_RS00400	ENOG4105CQ7	ATP-dependent helicase
H2O17_RS00425	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
H2O17_RS00430	ENOG4105ETE	Transcriptional regulator (LacI family
H2O17_RS00450	ENOG4105CNT	hydrolase family 2
H2O17_RS00460	ENOG4105CMR	udp-glucose 4-epimerase
H2O17_RS00475	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
H2O17_RS00505	ENOG4105DEI	Mannitol dehydrogenase
H2O17_RS00510	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
H2O17_RS00515	ENOG4108UHU	Aldolase
H2O17_RS00520	ENOG4105D7K	pfkb domain protein
H2O17_RS00540	ENOG4105CPQ	Dehydrogenase
H2O17_RS00600	ENOG410667J	hydrolase
H2O17_RS00605	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
H2O17_RS00615	ENOG4105CQC	Prephenate dehydratase
H2O17_RS00645	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
H2O17_RS00650	ENOG4108Z6B	deaminase
H2O17_RS00680	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H2O17_RS00695	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
H2O17_RS00700	ENOG4105CEY	Amp-dependent synthetase and ligase
H2O17_RS00705	ENOG4105D49	3-dehydroquinate synthase
H2O17_RS00720	ENOG4107RBB	ABC transporter, permease
H2O17_RS00735	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H2O17_RS00740	ENOG4105DEF	Extracellular solute-binding protein, family 5
H2O17_RS00750	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H2O17_RS00755	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H2O17_RS00790	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H2O17_RS00795	ENOG4105CTU	Proline racemase
H2O17_RS00805	ENOG4108WYP	Transcriptional regulator
H2O17_RS00820	ENOG4105DIN	metallophosphoesterase
H2O17_RS00825	ENOG4105BZ4	penicillin-binding protein
H2O17_RS00855	ENOG4105D74	hydrolase
H2O17_RS00905	ENOG4108I5C	dEAD DEAH box helicase
H2O17_RS00925	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
H2O17_RS00930	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
H2O17_RS00935	ENOG4105C6E	dna polymerase iii
H2O17_RS00980	ENOG4105VEQ	Cold shock protein
H2O17_RS00995	ENOG4108NNZ	chitinase
H2O17_RS01000	ENOG4105BZU	Histidine kinase
H2O17_RS01015	ENOG4105E2Y	ABC, transporter
H2O17_RS01020	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H2O17_RS01025	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
H2O17_RS01030	ENOG4105BZU	Histidine kinase
H2O17_RS01035	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H2O17_RS01040	ENOG4108VJ1	Transcriptional regulator (CarD family
H2O17_RS01045	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
H2O17_RS01050	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
H2O17_RS01060	ENOG4105C8N	cysteinyl-tRNA synthetase
H2O17_RS01065	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H2O17_RS01090	ENOG4105CSV	Glutaminase
H2O17_RS01095	ENOG4108KQ5	Integrase catalytic subunit
H2O17_RS01140	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
H2O17_RS01145	ENOG4105CFH	Aspartokinase
H2O17_RS01190	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
H2O17_RS01235	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
H2O17_RS01250	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
H2O17_RS01275	ENOG4105BZU	Histidine kinase
H2O17_RS01280	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H2O17_RS01285	ENOG41087YS	Phage shock protein A
H2O17_RS01295	ENOG4105VEQ	Cold shock protein
H2O17_RS01305	ENOG4105EIP	mannose-6-phosphate isomerase
H2O17_RS01310	ENOG4105C7N	Xanthine uracil vitamin C permease
H2O17_RS01315	ENOG4107Y80	Major Facilitator superfamily
H2O17_RS01325	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
H2O17_RS01365	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
H2O17_RS01375	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H2O17_RS01415	ENOG4108KQ5	Integrase catalytic subunit
H2O17_RS01445	ENOG4105CVR	type I restriction-modification system
H2O17_RS01460	ENOG4105DZR	Type I site-specific deoxyribonuclease
H2O17_RS01480	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
H2O17_RS01495	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
H2O17_RS01500	ENOG4105E90	ABC transporter
H2O17_RS01505	ENOG4105E90	ABC transporter
H2O17_RS01515	ENOG4105K7K	Transcriptional regulator
H2O17_RS01520	ENOG4105CIS	alcohol dehydrogenase
H2O17_RS01550	ENOG4105D56	permease protein
H2O17_RS01555	ENOG4105EG2	ABC transporter, permease
H2O17_RS01560	ENOG4105EVU	fructokinase
H2O17_RS01565	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
H2O17_RS01580	ENOG4105CG3	alpha amylase, catalytic region
H2O17_RS01590	ENOG4105EBR	Carboxylesterase
H2O17_RS01595	ENOG4105C72	UPF0176 protein
H2O17_RS01600	ENOG4105KPY	Small multidrug resistance protein
H2O17_RS01610	ENOG4105C0D	helicase
H2O17_RS01630	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
H2O17_RS01655	ENOG4108RWI	nicotinamidase
H2O17_RS01660	ENOG4105E98	transcriptional regulator DeoR family
H2O17_RS01670	ENOG4105DM4	PTS System
H2O17_RS01675	ENOG410849S	phosphocarrier protein (HPr)
H2O17_RS01680	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
H2O17_RS01685	ENOG4105F8V	Hydrolase, tatD family
H2O17_RS01700	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H2O17_RS01725	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
H2O17_RS01740	ENOG4107QWE	)-transporter
H2O17_RS01745	ENOG4105CFC	Transporter
H2O17_RS01750	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
H2O17_RS01760	ENOG4105WH1	Two component transcriptional regulator luxr family
H2O17_RS01775	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
H2O17_RS01780	ENOG4105C5H	ABC transporter
H2O17_RS01795	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
H2O17_RS01825	ENOG4108IUX	(ABC) transporter
H2O17_RS01840	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
H2O17_RS01845	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
H2O17_RS01860	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
H2O17_RS01865	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
H2O17_RS01880	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
H2O17_RS01900	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
H2O17_RS01925	ENOG4105CJ1	ABC, transporter
H2O17_RS01935	ENOG4108V1T	peptidylprolyl cis-trans isomerase
H2O17_RS01940	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H2O17_RS01945	ENOG4105E98	transcriptional regulator DeoR family
H2O17_RS01950	ENOG4107YVI	ribose 5-phosphate isomerase
H2O17_RS01955	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
H2O17_RS01960	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
H2O17_RS01975	ENOG4107Y7Q	pfkb domain protein
H2O17_RS01980	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H2O17_RS01985	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H2O17_RS01990	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
H2O17_RS02000	ENOG4105CGY	Dna recombination protein
H2O17_RS02005	ENOG4105C3G	gtp-binding protein
H2O17_RS02065	ENOG4108MTT	Glutamate-rich protein grpB
H2O17_RS02090	ENOG4107QUV	Domain protein
H2O17_RS02095	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
H2O17_RS02100	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
H2O17_RS02110	ENOG4105BZ1	(ABC) transporter
H2O17_RS02150	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
H2O17_RS02155	ENOG4107YJ4	chain length determinant protein
H2O17_RS02160	ENOG4105D3Q	Sugar transferase
H2O17_RS02170	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
H2O17_RS02215	ENOG4105C94	Transporter
H2O17_RS02240	ENOG4105DA5	(ABC) transporter
H2O17_RS02295	ENOG4105CPK	Glycosyl transferase (Group 1
H2O17_RS02315	ENOG4105K78	MarR family Transcriptional regulator
H2O17_RS02335	ENOG4105CEI	nitrite reductase
H2O17_RS02345	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H2O17_RS02355	ENOG4108JQ6	ABC transporter
H2O17_RS02360	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H2O17_RS02365	ENOG4105C85	amino acid
H2O17_RS02375	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H2O17_RS02380	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H2O17_RS02385	ENOG4108JQ6	ABC transporter
H2O17_RS02395	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
H2O17_RS02415	ENOG4105R3P	Inner membrane protein yagU
H2O17_RS02430	ENOG4105C85	amino acid
H2O17_RS02445	ENOG4108IQE	Amp-dependent synthetase and ligase
H2O17_RS02460	ENOG4105DA5	(ABC) transporter
H2O17_RS02480	ENOG4105DFH	Transport of potassium into the cell (By similarity)
H2O17_RS02485	ENOG4105DFM	M18 family aminopeptidase
H2O17_RS02490	ENOG4105CEY	Amp-dependent synthetase and ligase
H2O17_RS02495	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
H2O17_RS02500	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
H2O17_RS02520	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
H2O17_RS02535	ENOG4105CI3	gtp-binding protein typa
H2O17_RS02550	ENOG4108Z4U	Ferredoxin
H2O17_RS02565	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
H2O17_RS02570	ENOG4108JW7	Maf-like protein
H2O17_RS02585	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H2O17_RS02590	ENOG41065SU	Two-component system sensor kinase
H2O17_RS02610	ENOG4108KGH	TRANSCRIPTIONal
H2O17_RS02615	ENOG4108KGH	TRANSCRIPTIONal
H2O17_RS02630	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
H2O17_RS02650	ENOG4105EY8	ABC transporter
H2O17_RS02670	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
H2O17_RS02675	ENOG4105CKK	Glycosyl transferase, family 2
H2O17_RS02700	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
H2O17_RS02710	ENOG4105ECY	inositol monophosphatase
H2O17_RS02715	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
H2O17_RS02740	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H2O17_RS02745	ENOG4105BZU	Histidine kinase
H2O17_RS02750	ENOG4108T3R	lipoprotein lpqB
H2O17_RS02760	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
H2O17_RS02770	ENOG4108VPT	UPF0234 protein
H2O17_RS02790	ENOG4105WDJ	50S ribosomal protein L33
H2O17_RS02795	ENOG4107R4N	Cell wall formation (By similarity)
H2O17_RS02800	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
H2O17_RS02820	ENOG410683Z	Preprotein translocase SecE subunit
H2O17_RS02825	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
H2O17_RS02830	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
H2O17_RS02835	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
H2O17_RS02850	ENOG4108VZM	50s ribosomal protein L10
H2O17_RS02855	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
H2O17_RS02860	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H2O17_RS02865	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H2O17_RS02870	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
H2O17_RS02875	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
H2O17_RS02880	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
H2O17_RS02885	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
H2O17_RS02905	ENOG4105CI1	PTS System
H2O17_RS02915	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
H2O17_RS02920	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
H2O17_RS02925	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
H2O17_RS02930	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
H2O17_RS02935	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H2O17_RS02940	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
H2O17_RS02945	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
H2O17_RS02950	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
H2O17_RS02955	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
H2O17_RS02960	ENOG41082SA	50s ribosomal protein l29
H2O17_RS02965	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
H2O17_RS02970	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
H2O17_RS02975	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
H2O17_RS02980	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H2O17_RS02985	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
H2O17_RS02990	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
H2O17_RS02995	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
H2O17_RS03000	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
H2O17_RS03005	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
H2O17_RS03010	ENOG410849U	50S ribosomal protein L30
H2O17_RS03015	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
H2O17_RS03025	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
H2O17_RS03030	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
H2O17_RS03035	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
H2O17_RS03040	ENOG41067V7	50S ribosomal protein L36
H2O17_RS03045	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H2O17_RS03050	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
H2O17_RS03055	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H2O17_RS03060	ENOG4108ZT0	50S ribosomal protein l17
H2O17_RS03070	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
H2O17_RS03075	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
H2O17_RS03080	ENOG4108UJD	30S ribosomal protein S9
H2O17_RS03090	ENOG4105CS9	pantothenic acid kinase
H2O17_RS03095	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
H2O17_RS03105	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
H2O17_RS03110	ENOG4108097	ATP-binding protein
H2O17_RS03120	ENOG41072GX	Peptidase M22 Glycoprotease
H2O17_RS03140	ENOG4105E33	succinate dehydrogenase
H2O17_RS03145	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H2O17_RS03150	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
H2O17_RS03155	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H2O17_RS03160	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
H2O17_RS03165	ENOG4107QVP	Dehydrogenase
H2O17_RS03175	ENOG4107GFK	fumarate
H2O17_RS03180	ENOG4108ZJ4	polysaccharide deacetylase
H2O17_RS03200	ENOG4108IUW	ABC transporter
H2O17_RS03210	ENOG4106448	streptomycin biosynthesis protein strI
H2O17_RS03235	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
H2O17_RS03275	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
H2O17_RS03285	ENOG4107QRI	Phosphoketolase
H2O17_RS03295	ENOG4105PGM	cation diffusion facilitator family transporter
H2O17_RS03305	ENOG4105VMP	Transcriptional regulator
H2O17_RS03310	ENOG4105CHR	reductase
H2O17_RS03315	ENOG4105C7K	acetolactate synthase
H2O17_RS03320	ENOG4105E39	Enoyl-CoA hydratase
H2O17_RS03330	ENOG4105C1G	acyl-Coa dehydrogenase
H2O17_RS03335	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
H2O17_RS03340	ENOG4105C10	Electron transfer flavoprotein
H2O17_RS03360	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
H2O17_RS03365	ENOG4105C6K	Malic enzyme
H2O17_RS03375	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H2O17_RS03390	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H2O17_RS03455	ENOG41080R2	UPF0102 protein
H2O17_RS03480	ENOG4107QJE	Chromosome Partitioning Protein
H2O17_RS03535	ENOG4108KB2	LysR family Transcriptional regulator
H2O17_RS03550	ENOG4105C6N	Formate acetyltransferase
H2O17_RS03555	ENOG4105C6N	Formate acetyltransferase
H2O17_RS03565	ENOG4105C26	Dehydrogenase
H2O17_RS03575	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
H2O17_RS03585	ENOG4105CE4	GlcNAc 6-P deacetylase
H2O17_RS03590	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
H2O17_RS03610	ENOG4105DC1	bifunctional purine biosynthesis protein purh
H2O17_RS03615	ENOG4105C26	Dehydrogenase
H2O17_RS03640	ENOG4105CTQ	phosphohexokinase
H2O17_RS03645	ENOG4107QP8	phosphohexose isomerase
H2O17_RS03650	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
H2O17_RS03655	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
H2O17_RS03660	ENOG4108JIK	carboxylase
H2O17_RS03665	ENOG4105D8K	carboxyl transferase
H2O17_RS03675	ENOG4105IBS	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
H2O17_RS03680	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
H2O17_RS03685	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
H2O17_RS03700	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
H2O17_RS03705	ENOG4105DIH	basic membrane
H2O17_RS03710	ENOG4108JQ9	ABC transporter
H2O17_RS03715	ENOG4105UIB	(ABC) transporter
H2O17_RS03740	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
H2O17_RS03750	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
H2O17_RS03755	ENOG4108URH	decarboxylase
H2O17_RS03795	ENOG4105CJW	magnesium transporter
H2O17_RS03800	ENOG4107T6F	Xaa-Pro aminopeptidase
H2O17_RS03810	ENOG41081FY	multiple antibiotic resistance (MarC)-related
H2O17_RS03815	ENOG410667J	hydrolase
H2O17_RS03820	ENOG4105C1J	atp-dependent rna helicase
H2O17_RS03830	ENOG4105C4R	Atp-dependent dna helicase
H2O17_RS03845	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
H2O17_RS03850	ENOG4105CAK	Cell division ATP-binding protein ftsE
H2O17_RS03855	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
H2O17_RS03860	ENOG4105DR5	peptidase
H2O17_RS03865	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
H2O17_RS03895	ENOG41089UC	methyltransferase, type 11
H2O17_RS03905	ENOG4105C87	Aminotransferase class I and II
H2O17_RS03910	ENOG4105DXI	Major Facilitator superfamily
H2O17_RS03925	ENOG4105KTU	Transcriptional regulator, arsr family
H2O17_RS04120	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
H2O17_RS04220	ENOG4105CPQ	Dehydrogenase
H2O17_RS04240	ENOG4105C0B	DNA polymerase III (alpha subunit)
H2O17_RS04245	ENOG4105CNU	cell division protein FtsK
H2O17_RS04335	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
H2O17_RS04360	ENOG4107J0C	type IIi
H2O17_RS04365	ENOG4107QMH	DNA methylase
H2O17_RS04570	ENOG4108IQE	Amp-dependent synthetase and ligase
H2O17_RS04585	ENOG41082SX	arsR family transcriptional regulator
H2O17_RS04590	ENOG4105C59	p-type ATPase
H2O17_RS04595	ENOG4108426	dNA-binding protein
H2O17_RS04615	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
H2O17_RS04625	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
H2O17_RS04630	ENOG4108RQ5	Beta-lactamase domain-containing protein
H2O17_RS04635	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
H2O17_RS04640	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
H2O17_RS04660	ENOG4108R5T	secreted protein
H2O17_RS04670	ENOG41079KZ	Major Facilitator Superfamily
H2O17_RS04705	ENOG4105CIG	ABC transporter
H2O17_RS04715	ENOG4105C87	Aminotransferase class I and II
H2O17_RS04720	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
H2O17_RS04745	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
H2O17_RS04750	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
H2O17_RS04755	ENOG4105EPJ	extracellular solute-binding protein family 1
H2O17_RS04780	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H2O17_RS04785	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H2O17_RS04790	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
H2O17_RS04815	ENOG4105CPF	Cell wall formation (By similarity)
H2O17_RS04835	ENOG4108RMH	femAB family
H2O17_RS04840	ENOG4105VB9	50S ribosomal protein l28
H2O17_RS04845	ENOG4105CB5	ATP-dependent DNA helicase recG
H2O17_RS04850	ENOG4106H78	methyltransferase
H2O17_RS04855	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
H2O17_RS04870	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
H2O17_RS04875	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
H2O17_RS04910	ENOG4108JJ8	(ABC) transporter
H2O17_RS04915	ENOG4108JJ9	ABC, transporter
H2O17_RS04920	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
H2O17_RS04925	ENOG4105C4M	(Ubiquinol oxidase) subunit I
H2O17_RS04930	ENOG4105C03	ribonuclease
H2O17_RS04935	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
H2O17_RS04940	ENOG4105K46	50S ribosomal protein l27
H2O17_RS04945	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H2O17_RS04950	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
H2O17_RS04960	ENOG41080RH	Thioredoxin
H2O17_RS04965	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
H2O17_RS04970	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H2O17_RS04985	ENOG4105CVJ	phosphoglycerate mutase
H2O17_RS05030	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H2O17_RS05045	ENOG4105DQ5	transport system permease protein
H2O17_RS05050	ENOG4105TVJ	transport system, permease
H2O17_RS05055	ENOG4105E0A	ABC, transporter
H2O17_RS05085	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
H2O17_RS05100	ENOG4105WYW	fructose-bisphosphate aldolase
H2O17_RS05105	ENOG4105CMQ	Chloride channel
H2O17_RS05135	ENOG4105C0D	helicase
H2O17_RS05140	ENOG4105C0D	helicase
H2O17_RS05170	ENOG4105CPC	Aldo Keto reductase
H2O17_RS05195	ENOG4108ZHJ	Organic hydroperoxide resistance protein
H2O17_RS05200	ENOG4105K56	Transcriptional regulator
H2O17_RS05210	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H2O17_RS05225	ENOG4108UZX	fmn reductase
H2O17_RS05240	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H2O17_RS05265	ENOG4105EFZ	amidohydrolase
H2O17_RS05280	ENOG4105C19	ABC transporter
H2O17_RS05305	ENOG4105D01	(LipO)protein
H2O17_RS05310	ENOG4108UMI	ABC transporter, permease
H2O17_RS05315	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
H2O17_RS05325	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
H2O17_RS05345	ENOG4105C8T	Leucyl-tRNA synthetase
H2O17_RS05360	ENOG4108EC8	DNA internalization-related competence protein ComEC
H2O17_RS05370	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H2O17_RS05375	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H2O17_RS05390	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
H2O17_RS05400	ENOG4107TB5	TRANSCRIPTIONal
H2O17_RS05425	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
H2O17_RS05430	ENOG4108MWI	inositol mono-phosphatase
H2O17_RS05435	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
H2O17_RS05450	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
H2O17_RS05455	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H2O17_RS05470	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
H2O17_RS05480	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
H2O17_RS05490	ENOG4108ZF3	Phosphatase
H2O17_RS05505	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
H2O17_RS05510	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
H2O17_RS05520	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
H2O17_RS05525	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
H2O17_RS05530	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
H2O17_RS05550	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
H2O17_RS05560	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
H2O17_RS05565	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
H2O17_RS05575	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
H2O17_RS05580	ENOG41084BS	50S ribosomal protein L35
H2O17_RS05585	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
H2O17_RS05590	ENOG4108RWN	rrna methyltransferase
H2O17_RS05600	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
H2O17_RS05605	ENOG4105DDK	oxidoreductase, beta subunit
H2O17_RS05625	ENOG4108DBC	nitroreductase
H2O17_RS05635	ENOG4105DBV	ornithine carbamoyltransferase
H2O17_RS05640	ENOG4105CH7	arginosuccinase
H2O17_RS05645	ENOG4108VX5	3-methyladenine DNA glycosylase
H2O17_RS05650	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
H2O17_RS05685	ENOG4105DSU	hydrolase
H2O17_RS05700	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
H2O17_RS05725	ENOG4105CJR	Integral membrane protein (MviN
H2O17_RS05730	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
H2O17_RS05755	ENOG4105JRK	feS assembly protein SufD
H2O17_RS05765	ENOG4105C3K	feS assembly ATPase SufC
H2O17_RS05775	ENOG4108UNV	SUF system FeS assembly protein, NifU family
H2O17_RS05780	ENOG4105VG1	fes assembly suf system protein
H2O17_RS05785	ENOG4105C5H	ABC transporter
H2O17_RS05800	ENOG4105D7N	magnesium and cobalt transport protein CorA
H2O17_RS05805	ENOG4105EAC	phosphoserine phosphatase
H2O17_RS05815	ENOG4107QPH	glycogen) synthase
H2O17_RS05820	ENOG4105DKW	ABC transporter
H2O17_RS05845	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
H2O17_RS05850	ENOG4108V1U	phospholipid-binding protein
H2O17_RS05865	ENOG4105C0B	DNA polymerase III (alpha subunit)
H2O17_RS05885	ENOG4105C5Y	PTS System
H2O17_RS05890	ENOG4105CS2	ec 3.2.1.21
H2O17_RS05910	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
H2O17_RS05920	ENOG4105CPC	Aldo Keto reductase
H2O17_RS05925	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
H2O17_RS05940	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
H2O17_RS05945	ENOG4105E5F	proteasome
H2O17_RS05950	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
H2O17_RS05955	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
H2O17_RS05965	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
H2O17_RS05970	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
H2O17_RS05980	ENOG4105DK0	Indole-3-glycerol phosphate synthase
H2O17_RS05985	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
H2O17_RS05990	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
H2O17_RS05995	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
H2O17_RS06000	ENOG4105CBC	glutamate synthase
H2O17_RS06035	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H2O17_RS06040	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
H2O17_RS06045	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
H2O17_RS06050	ENOG4105C28	cystathionine
H2O17_RS06055	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
H2O17_RS06060	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H2O17_RS06065	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
H2O17_RS06075	ENOG4105DHU	Bile acid
H2O17_RS06090	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
H2O17_RS06095	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
H2O17_RS06105	ENOG4105CIE	May be required for sporulation (By similarity)
H2O17_RS06110	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
H2O17_RS06115	ENOG4105BZA	Phosphoglycerate kinase
H2O17_RS06120	ENOG4105CP7	Triose-phosphate isomerase
H2O17_RS06160	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
H2O17_RS06170	ENOG4105CAT	Cytidine monophosphate kinase
H2O17_RS06175	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
H2O17_RS06190	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H2O17_RS06195	ENOG4108SGK	Tetr family transcriptional regulator
H2O17_RS06200	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
H2O17_RS06205	ENOG4105CEU	Arginine dihydrolase
H2O17_RS06250	ENOG4107TXC	Transcriptional regulator
H2O17_RS06370	ENOG4105DEF	Extracellular solute-binding protein, family 5
H2O17_RS06380	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H2O17_RS06410	ENOG4105DZW	Dipeptidase
H2O17_RS06420	ENOG4105C4C	beta-galactosidase
H2O17_RS06435	ENOG4105CPQ	Dehydrogenase
H2O17_RS06440	ENOG4108UW8	fha domain-containing protein
H2O17_RS06460	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
H2O17_RS06470	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
H2O17_RS06485	ENOG4107TE5	Lipid kinase
H2O17_RS06510	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
H2O17_RS06515	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
H2O17_RS06520	ENOG4107XKF	NMT1 THI5 Like Domain Protein
H2O17_RS06525	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
H2O17_RS06530	ENOG4107R13	MMPL domain protein
H2O17_RS06535	ENOG4105CK7	Sodium proline symporter
H2O17_RS06540	ENOG4105CSR	polyphosphate kinase 2
H2O17_RS06545	ENOG4105DJV	ribulose-phosphate 3-epimerase
H2O17_RS06555	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
H2O17_RS06565	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
H2O17_RS06575	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
H2O17_RS06580	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
H2O17_RS06585	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
H2O17_RS06590	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
H2O17_RS06595	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
H2O17_RS06605	ENOG4105CD3	dihydroorotase
H2O17_RS06610	ENOG4105CXT	aspartate transcarbamylase
H2O17_RS06615	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
H2O17_RS06620	ENOG410803B	Involved in the transcription termination process (By similarity)
H2O17_RS06625	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
H2O17_RS06640	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
H2O17_RS06660	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
H2O17_RS06665	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
H2O17_RS06675	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
H2O17_RS06690	ENOG4105C9M	aspartyl-trna synthetase
H2O17_RS06705	ENOG4105D22	carbon starvation protein
H2O17_RS06725	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
H2O17_RS06730	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
H2O17_RS06745	ENOG4105CDH	Citrulline--aspartate ligase
H2O17_RS06755	ENOG4105C8Y	Acetylornithine aminotransferase
H2O17_RS06760	ENOG4105CAS	nag kinase
H2O17_RS06765	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
H2O17_RS06770	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
H2O17_RS06785	ENOG4105CUT	histidyl-tRNA synthetase
H2O17_RS06790	ENOG4105C5X	domain protein
H2O17_RS06795	ENOG4105C99	atpase involved in dna repair
H2O17_RS06805	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H2O17_RS06810	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
H2O17_RS06815	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H2O17_RS06820	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H2O17_RS06830	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
H2O17_RS06835	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
H2O17_RS06840	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
H2O17_RS06845	ENOG4105CDY	transcriptional regulatory protein
H2O17_RS06850	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
H2O17_RS06865	ENOG4105E2K	Glycosyl transferase (Group 1
H2O17_RS06880	ENOG4105E2D	ec 3.2.1.52
H2O17_RS06915	ENOG4105C22	threonyL-tRNA synthetase
H2O17_RS07000	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
H2O17_RS07005	ENOG4107QM5	aconitate hydratase
H2O17_RS07010	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H2O17_RS07020	ENOG4107VEG	TrkA-N domain protein
H2O17_RS07055	ENOG4107W53	thymidine kinase
H2O17_RS07070	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H2O17_RS07080	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H2O17_RS07090	ENOG4108JDX	DNA polymerase iii, epsilon subunit
H2O17_RS07095	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H2O17_RS07100	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H2O17_RS07105	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
H2O17_RS07110	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
H2O17_RS07130	ENOG4105C57	major facilitator superfamily
H2O17_RS07145	ENOG4105E4C	Lytic transglycosylase catalytic
H2O17_RS07155	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
H2O17_RS07180	ENOG4108I0Q	anthranilate phosphoribosyltransferase
H2O17_RS07210	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H2O17_RS07220	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
H2O17_RS07230	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
H2O17_RS07255	ENOG4105C5F	glutamine synthetase
H2O17_RS07260	ENOG4108HW3	(ABC) transporter
H2O17_RS07265	ENOG4105E5Q	amino acid AbC transporter
H2O17_RS07270	ENOG4108JEH	abc transporter atp-binding protein
H2O17_RS07275	ENOG4105GCF	PGAM
H2O17_RS07280	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
H2O17_RS07285	ENOG4105C5F	glutamine synthetase
H2O17_RS07295	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
H2O17_RS07320	ENOG410802Z	Protein of unknown function (DUF328)
H2O17_RS07330	ENOG4105EGD	dinuclear metal center protein, YbgI family
H2O17_RS07340	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
H2O17_RS07370	ENOG4108XM1	transcriptional regulator AsnC family
H2O17_RS07380	ENOG4105M6F	mutator MutT protein
H2O17_RS07385	ENOG4105C7K	acetolactate synthase
H2O17_RS07395	ENOG4105K8R	UPF0145 protein
H2O17_RS07400	ENOG4105CDA	abc transporter atp-binding protein
H2O17_RS07405	ENOG4105DRP	amino acid AbC transporter
H2O17_RS07410	ENOG4108Q1T	ABC transporter
H2O17_RS07415	ENOG4107UBR	Extracellular solute-binding protein family 3
H2O17_RS07435	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
H2O17_RS07440	ENOG4106V2I	dimethylaminohydrolase
H2O17_RS07455	ENOG4105DIM	ABC transporter
H2O17_RS07460	ENOG4105CIG	ABC transporter
H2O17_RS07485	ENOG41089UC	methyltransferase, type 11
H2O17_RS07500	ENOG4105EYH	Exonuclease
H2O17_RS07530	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H2O17_RS07560	ENOG4105F9F	transposase
H2O17_RS07585	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
H2O17_RS07600	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
H2O17_RS07605	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
H2O17_RS07630	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H2O17_RS07650	ENOG4108RMH	femAB family
H2O17_RS07665	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
H2O17_RS07670	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
H2O17_RS07700	ENOG4108Z0Z	intracellular protease Pfpi family
H2O17_RS07705	ENOG4105DQ4	alcohol dehydrogenase
H2O17_RS07720	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H2O17_RS07725	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
H2O17_RS07735	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H2O17_RS07740	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
H2O17_RS07745	ENOG4105DSE	periplasmic solute binding protein
H2O17_RS07750	ENOG4105DIK	(ABC) transporter
H2O17_RS07755	ENOG4105CC5	ABC transporter
H2O17_RS07760	ENOG4105I3K	Ferric uptake regulator, Fur family
H2O17_RS07775	ENOG4105C0B	DNA polymerase III (alpha subunit)
H2O17_RS07780	ENOG4108HPG	-acetyltransferase
H2O17_RS07790	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
H2O17_RS07805	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
H2O17_RS07810	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
H2O17_RS07815	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
H2O17_RS07825	ENOG4105DFU	Cell wall formation (By similarity)
H2O17_RS07835	ENOG4105CNI	cell division protein FtsW
H2O17_RS07840	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
H2O17_RS07845	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
H2O17_RS07855	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
H2O17_RS07860	ENOG4105CJN	penicillin-binding protein
H2O17_RS07870	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
H2O17_RS07875	ENOG4108V6E	Cell division protein mraZ
H2O17_RS07910	ENOG4108JQ1	Dehydrogenase
H2O17_RS07915	ENOG4105CEY	Amp-dependent synthetase and ligase
H2O17_RS07920	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
H2O17_RS07930	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
H2O17_RS07945	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H2O17_RS07950	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
H2O17_RS07955	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
H2O17_RS07960	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
H2O17_RS07965	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
H2O17_RS07970	ENOG4105KC9	Modulates RecA activity (By similarity)
H2O17_RS07975	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
H2O17_RS07985	ENOG4105WBV	Transcriptional regulator
H2O17_RS07990	ENOG4105CEV	competence damage-inducible protein
H2O17_RS08005	ENOG4107QZI	cell division protein FtsK
H2O17_RS08015	ENOG4105CN5	Metallo-Beta-Lactamase
H2O17_RS08020	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H2O17_RS08030	ENOG4105CTQ	phosphohexokinase
H2O17_RS08035	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
H2O17_RS08040	ENOG4105C1V	Peptidase, M16
H2O17_RS08045	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
H2O17_RS08050	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
H2O17_RS08065	ENOG4105CTX	dehydratase
H2O17_RS08070	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
H2O17_RS08075	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
H2O17_RS08080	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
H2O17_RS08080	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
H2O17_RS08095	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
H2O17_RS08115	ENOG4108C33	Resolvase
H2O17_RS08130	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
H2O17_RS08140	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
H2O17_RS08145	ENOG4105DZP	Membrane-associated zinc metalloprotease
H2O17_RS08150	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
H2O17_RS08160	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
H2O17_RS08170	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
H2O17_RS08175	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
H2O17_RS08185	ENOG4105CAG	UPF0210 protein
H2O17_RS08190	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
H2O17_RS08195	ENOG4105CE9	30S ribosomal protein S2
H2O17_RS08205	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H2O17_RS08220	ENOG41080R2	UPF0102 protein
H2O17_RS08230	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H2O17_RS08235	ENOG4107QYR	Signal peptidase i
H2O17_RS08240	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
H2O17_RS08245	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
H2O17_RS08250	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
H2O17_RS08255	ENOG41082KU	UPF0109 protein
H2O17_RS08260	ENOG4105K5M	30s ribosomal protein S16
H2O17_RS08280	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
H2O17_RS08295	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
H2O17_RS08310	ENOG4105KRI	phosphocarrier protein (HPr
H2O17_RS08315	ENOG4108UTZ	Dihydroxyacetone kinase
H2O17_RS08320	ENOG4105CMT	Dihydroxyacetone kinase
H2O17_RS08325	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
H2O17_RS08330	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H2O17_RS08335	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
H2O17_RS08340	ENOG4105ETE	Transcriptional regulator (LacI family
H2O17_RS08350	ENOG4105DRS	transport system, permease
H2O17_RS08355	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
H2O17_RS08370	ENOG4105II7	pyrroline-5-carboxylate reductase
H2O17_RS08385	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
H2O17_RS08390	ENOG4108IQE	Amp-dependent synthetase and ligase
H2O17_RS08395	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
H2O17_RS08400	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
H2O17_RS08405	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H2O17_RS08410	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H2O17_RS08415	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
H2O17_RS08465	ENOG4105PF9	Transcriptional regulator
H2O17_RS08470	ENOG4105EYF	MMPL domain protein
H2O17_RS08480	ENOG41068HZ	50S ribosomal protein L32
H2O17_RS08485	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
H2O17_RS08490	ENOG4105C6T	cysteine synthase
H2O17_RS08495	ENOG4105D7W	serine acetyltransferase
H2O17_RS08500	ENOG4108YZG	isomerase
H2O17_RS08505	ENOG4105C9K	Endothelin-converting enzyme 1
H2O17_RS08515	ENOG4105C5Y	PTS System
H2O17_RS08530	ENOG4105C29	acyl-CoA thioesterase
H2O17_RS08585	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
H2O17_RS08595	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
H2O17_RS08600	ENOG4105CSH	Transporter
H2O17_RS08610	ENOG4108JJB	ABC transporter
H2O17_RS08615	ENOG4107ZYJ	bioY protein
H2O17_RS08625	ENOG4105EAB	amino acid AbC transporter
H2O17_RS08630	ENOG4105E5Q	amino acid AbC transporter
H2O17_RS08635	ENOG4105E5Q	amino acid AbC transporter
H2O17_RS08640	ENOG4105CDA	abc transporter atp-binding protein
H2O17_RS08660	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
H2O17_RS08665	ENOG4108RYK	Nad-dependent epimerase dehydratase
H2O17_RS08670	ENOG4105KVH	Transcriptional regulator
H2O17_RS08675	ENOG4105NAE	bifunctional deaminase-reductase domain protein
H2O17_RS08685	ENOG41061H0	Monooxygenase
H2O17_RS08770	ENOG4105VPX	protein, conserved in bacteria
H2O17_RS08780	ENOG4105IJJ	transcriptional regulator, crp fnr family
H2O17_RS08860	ENOG4108UUM	single-stranded DNA-binding protein
H2O17_RS08900	ENOG4107WGA	YidE YbjL
H2O17_RS08935	ENOG4105DFA	alanine racemase domain protein
H2O17_RS08940	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
H2O17_RS08945	ENOG4105CM2	brancheD-chain amino acid aminotransferase
H2O17_RS08950	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H2O17_RS08955	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
H2O17_RS08970	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H2O17_RS08985	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
H2O17_RS08990	ENOG4108ZP8	Acetolactate synthase small subunit
H2O17_RS08995	ENOG4105C7K	acetolactate synthase
H2O17_RS09010	ENOG4105D0C	transport protein
H2O17_RS09015	ENOG4105C01	Dihydroxy-acid dehydratase
H2O17_RS09020	ENOG4105BZ1	(ABC) transporter
H2O17_RS09025	ENOG4108JJ9	ABC, transporter
H2O17_RS09030	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
H2O17_RS09035	ENOG4105EHG	Permease protein
H2O17_RS09055	ENOG4105CH6	catalase
H2O17_RS09060	ENOG4105E2V	Glycosyltransferase 36
H2O17_RS09075	ENOG4108YYC	ycei family
H2O17_RS09100	ENOG4105ETE	Transcriptional regulator (LacI family
H2O17_RS09140	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H2O17_RS09145	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H2O17_RS09150	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H2O17_RS09155	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H2O17_RS09160	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
H2O17_RS09190	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
H2O17_RS09210	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
H2O17_RS09215	ENOG4105BZ1	(ABC) transporter
H2O17_RS09225	ENOG4105ST3	Transcriptional regulator
H2O17_RS09230	ENOG4105C9Q	fumarate hydratase class II
H2O17_RS09245	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
H2O17_RS09255	ENOG4105DSB	aldose 1-epimerase
H2O17_RS09260	ENOG4105C0A	alcohol dehydrogenase
H2O17_RS09265	ENOG41082JN	Transcriptional regulator
H2O17_RS09285	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
H2O17_RS09290	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
H2O17_RS09300	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
H2O17_RS09320	ENOG4105DJZ	UPF0182 protein
H2O17_RS09330	ENOG41063PX	domain protein
H2O17_RS09360	ENOG4105C31	Tryptophanyl-tRNA synthetase
H2O17_RS09370	ENOG4105DZC	cytosine deaminase
H2O17_RS09385	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
H2O17_RS09395	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
H2O17_RS09400	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
H2O17_RS09440	ENOG4105CE4	GlcNAc 6-P deacetylase
H2O17_RS09445	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
H2O17_RS09460	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
H2O17_RS09465	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
H2O17_RS09470	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
H2O17_RS09475	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H2O17_RS09480	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
H2O17_RS09485	ENOG4105ZA1	atp synthase
H2O17_RS09490	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
H2O17_RS09500	ENOG4105ESV	Glycosyl transferase, family 4
H2O17_RS09510	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
H2O17_RS09515	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
H2O17_RS09520	ENOG4105VFB	Binds the 23S rRNA (By similarity)
H2O17_RS09530	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
H2O17_RS09535	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
H2O17_RS09540	ENOG4105D6E	homoserine dehydrogenase
H2O17_RS09545	ENOG4105FF2	Type I DHQase
H2O17_RS09555	ENOG4105C75	arginyL-tRNA synthetase
H2O17_RS09565	ENOG4105K5B	UPF0225 protein
H2O17_RS09570	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
H2O17_RS09575	ENOG4105E4C	Lytic transglycosylase catalytic
H2O17_RS09585	ENOG4105C37	(CBS) domain
H2O17_RS09590	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
H2O17_RS09620	ENOG4105EMN	RNA polymerase sigma factor
H2O17_RS09630	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
H2O17_RS09635	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
H2O17_RS09640	ENOG4107TK4	histidinol-phosphate phosphatase
H2O17_RS09645	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
H2O17_RS09655	ENOG4105EYH	Exonuclease
H2O17_RS09670	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
H2O17_RS09680	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H2O17_RS09690	ENOG4105D65	subunit l
H2O17_RS09695	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H2O17_RS09700	ENOG41087XN	oxidoreductase
H2O17_RS09705	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H2O17_RS09710	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
H2O17_RS09715	ENOG4108IEH	NADH dehydrogenase subunit g
H2O17_RS09720	ENOG4107QIZ	NADH dehydrogenase
H2O17_RS09730	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H2O17_RS09735	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H2O17_RS09740	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H2O17_RS09750	ENOG4105P52	geranylgeranyl reductase
H2O17_RS09755	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H2O17_RS09760	ENOG4107SIQ	Naphthoate synthase
H2O17_RS09780	ENOG4108RH7	phosphoglycerate mutase
H2O17_RS09810	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
H2O17_RS09820	ENOG4105CEN	a g-specific adenine glycosylase
H2O17_RS09840	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
H2O17_RS09850	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
H2O17_RS09855	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
H2O17_RS09860	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
H2O17_RS09865	ENOG4105DAA	L-lactate
H2O17_RS09870	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
H2O17_RS09875	ENOG4107QR9	Iron-sulfur cluster binding protein
H2O17_RS09880	ENOG41080R8	Conserved Protein
H2O17_RS09895	ENOG4105CRK	lysyL-tRNA synthetase
H2O17_RS09900	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
H2O17_RS09905	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
H2O17_RS09915	ENOG4108V06	Glutathione peroxidase
H2O17_RS09940	ENOG4105EEI	dihydropteroate synthase
H2O17_RS09945	ENOG4105EUJ	GTP cyclohydrolase i
H2O17_RS09950	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H2O17_RS09960	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
H2O17_RS09975	ENOG4105F0N	pyrophosphate phospho-hydrolase
H2O17_RS09985	ENOG4108IQK	o-acetylhomoserine
H2O17_RS09990	ENOG4105DWV	Homoserine O-trans-acetylase
H2O17_RS10005	ENOG4105CQB	FAD linked oxidase domain protein
H2O17_RS10020	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
H2O17_RS10025	ENOG4105CKU	formyltetrahydrofolate synthetase
H2O17_RS10030	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H2O17_RS10035	ENOG4105ETE	Transcriptional regulator (LacI family
H2O17_RS10045	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
H2O17_RS10050	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
H2O17_RS10055	ENOG4105C2J	ABC transporter
H2O17_RS10060	ENOG4107R9N	ABC transporter
H2O17_RS10065	ENOG41062B0	ABC transporter, permease
H2O17_RS10070	ENOG4108RVA	ribokinase
H2O17_RS10075	ENOG4105CPQ	Dehydrogenase
H2O17_RS10080	ENOG4105CT4	transporter
H2O17_RS10085	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
H2O17_RS10090	ENOG4108HHA	Transketolase
H2O17_RS10100	ENOG4105ETE	Transcriptional regulator (LacI family
H2O17_RS10160	ENOG4105I82	acetyl xylan esterase
H2O17_RS10165	ENOG4105MP0	transposase
H2O17_RS10170	ENOG4105ETE	Transcriptional regulator (LacI family
H2O17_RS10185	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
H2O17_RS10200	ENOG4105EEQ	Na H antiporter
H2O17_RS10220	ENOG4105ETE	Transcriptional regulator (LacI family
H2O17_RS10225	ENOG4105C93	Xylose Isomerase
H2O17_RS10240	ENOG4107WI4	Aldose-1-epimerase
H2O17_RS10250	ENOG4108MKX	Triose-phosphate isomerase
H2O17_RS10255	ENOG4105CMT	Dihydroxyacetone kinase
H2O17_RS10265	ENOG4105CHR	reductase
H2O17_RS10270	ENOG4105CSP	Major Facilitator Superfamily
H2O17_RS10290	ENOG4106ETB	IIa component
H2O17_RS10300	ENOG4105CV1	Transketolase (EC 2.2.1.1)
H2O17_RS10310	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
H2O17_RS10325	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
H2O17_RS10335	ENOG4107NHD	transcriptional regulator
H2O17_RS10345	ENOG4105CJ3	phosphate transporter
H2O17_RS10350	ENOG4105EEQ	Na H antiporter
H2O17_RS10375	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H2O17_RS10390	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
H2O17_RS10405	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
H2O17_RS10425	ENOG4105EB3	Histidine kinase
H2O17_RS10430	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H2O17_RS10435	ENOG4107AQZ	Membrane
H2O17_RS10445	ENOG4105E0X	reductase
H2O17_RS10515	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
H2O17_RS10535	ENOG4107R37	Glutamate dehydrogenase
H2O17_RS10540	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
H2O17_RS10545	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
H2O17_RS10555	ENOG4105C8V	SAICAR synthetase
H2O17_RS10560	ENOG4105C12	Phosphoribosylglycinamide synthetase
H2O17_RS10570	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
H2O17_RS10580	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
H2O17_RS10610	ENOG4107RCW	fructose-bisphosphate aldolase
H2O17_RS10625	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
H2O17_RS10630	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H2O17_RS10640	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H2O17_RS10670	ENOG4105EMU	Dehydrogenase
H2O17_RS10675	ENOG4105CGK	Exodeoxyribonuclease III
H2O17_RS10695	ENOG4105BZG	amino acid carrier protein
H2O17_RS10700	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H2O17_RS10710	ENOG4108Z66	YbaK ebsC protein
H2O17_RS10725	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
H2O17_RS10735	ENOG4105CG3	alpha amylase, catalytic region
H2O17_RS10755	ENOG4105DJ2	Major Facilitator Superfamily
H2O17_RS10770	ENOG4105CFG	Acts as a chaperone (By similarity)
H2O17_RS10775	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H2O17_RS10780	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H2O17_RS10785	ENOG4105KNI	merR family transcriptional Regulator
H2O17_RS10795	ENOG4108UCS	ABC, transporter
H2O17_RS10820	ENOG410684G	monovalent cation H antiporter subunit F
H2O17_RS10830	ENOG4108JPZ	Monovalent cation H antiporter subunit D
H2O17_RS10835	ENOG4105MKQ	Monovalent cation H antiporter subunit C
H2O17_RS10840	ENOG4105D65	subunit l
H2O17_RS10845	ENOG4105DHP	deoxycytidine triphosphate deaminase
H2O17_RS10850	ENOG4107TCW	O-succinylbenzoate synthase
H2O17_RS10855	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
H2O17_RS10865	ENOG4105E4F	Isochorismate synthase
H2O17_RS10890	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H2O17_RS10900	ENOG41082T9	Membrane
H2O17_RS10905	ENOG4107QTF	adenylosuccinate lyase
H2O17_RS10910	ENOG4107T5V	SNARE associated Golgi
H2O17_RS10930	ENOG4105C2W	permease
H2O17_RS10935	ENOG4105WMR	Protein CrcB homolog
H2O17_RS10940	ENOG4105WMR	Protein CrcB homolog
H2O17_RS10955	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
H2O17_RS10965	ENOG4105DIA	mandelate racemase muconate lactonizing
H2O17_RS10970	ENOG4105JXH	GntR family transcriptional regulator
H2O17_RS10975	ENOG4105BZW	Glycerate kinase
H2O17_RS10980	ENOG4105EQX	glucarate dehydratase
H2O17_RS10985	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
H2O17_RS10990	ENOG4105C6Z	Gluconate
H2O17_RS10995	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H2O17_RS11000	ENOG4107HP6	Transcriptional regulator
H2O17_RS11010	ENOG4105EN6	Membrane
H2O17_RS11030	ENOG4105CQ7	ATP-dependent helicase
H2O17_RS11040	ENOG4107QRT	dEAD DEAH box helicase
H2O17_RS11065	ENOG4105C5R	Aminotransferase
H2O17_RS11090	ENOG4105DEF	Extracellular solute-binding protein, family 5
H2O17_RS11095	ENOG4105CI2	imidazolone-5-propionate hydrolase
H2O17_RS11125	ENOG4105H3G	oxidoreductase
H2O17_RS11130	ENOG4105WAB	arsR family transcriptional regulator
H2O17_RS11155	ENOG4105DEF	Extracellular solute-binding protein, family 5
H2O17_RS11170	ENOG4108JQ7	(ABC) transporter
H2O17_RS11175	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H2O17_RS11180	ENOG4105DKQ	ROK family
H2O17_RS11185	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
H2O17_RS11190	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
H2O17_RS11195	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
H2O17_RS11215	ENOG4105KJF	protein tyrosine phosphatase
H2O17_RS11225	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H2O17_RS11235	ENOG4105C8P	)-transporter
H2O17_RS11240	ENOG4105CUX	Signal transduction histidine kinase
H2O17_RS11265	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H2O17_RS11270	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
H2O17_RS11280	ENOG4105EJQ	L-serine dehydratase
H2O17_RS11305	ENOG4105D2H	Uronic isomerase
H2O17_RS11315	ENOG4105CT4	transporter
H2O17_RS11320	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
H2O17_RS11325	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
H2O17_RS11330	ENOG4107YH6	single-stranded DNA-binding protein
H2O17_RS11335	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
H2O17_RS11340	ENOG4105BZ4	penicillin-binding protein
H2O17_RS11345	ENOG4105DSF	transport protein
H2O17_RS11355	ENOG4105CZA	synthase
H2O17_RS11365	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
H2O17_RS11385	ENOG4105C3M	thioredoxin reductase
H2O17_RS11395	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H2O17_RS11410	ENOG4107QJE	Chromosome Partitioning Protein
H2O17_RS11420	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
H2O17_RS11430	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins