locus-tag	class	description
ARCVE_RS00010	COG0003	Pfam Anion-transporting ATPase
ARCVE_RS00020	COG1793	dna ligase
ARCVE_RS00020	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ARCVE_RS00170	COG2409	Drug exporters of the RND superfamily
ARCVE_RS00215	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ARCVE_RS00225	COG1522	sequence-specific DNA binding
ARCVE_RS00230	COG0647	UMP catabolic process
ARCVE_RS00240	COG0572	uridine kinase
ARCVE_RS00250	COG2414	aldehyde ferredoxin oxidoreductase
ARCVE_RS00290	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ARCVE_RS00315	COG3547	Transposase (IS116 IS110 IS902 family)
ARCVE_RS00320	COG0352	thiamine-phosphate diphosphorylase activity
ARCVE_RS00330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ARCVE_RS00350	COG1047	Peptidyl-prolyl cis-trans
ARCVE_RS00365	COG1694	Mazg nucleotide pyrophosphohydrolase
ARCVE_RS00380	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ARCVE_RS00435	COG2131	deaminase
ARCVE_RS00440	COG0084	hydrolase, TatD family'
ARCVE_RS00450	COG2239	Acts as a magnesium transporter
ARCVE_RS00455	COG0140	phosphoribosyl-ATP diphosphatase activity
ARCVE_RS00465	COG0116	Belongs to the methyltransferase superfamily
ARCVE_RS00465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ARCVE_RS00470	COG0110	maltose O-acetyltransferase activity
ARCVE_RS00480	COG0613	PHP domain protein
ARCVE_RS00500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ARCVE_RS00500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ARCVE_RS00525	COG4962	Type ii secretion system protein e
ARCVE_RS00575	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ARCVE_RS00585	COG0142	geranyltranstransferase activity
ARCVE_RS00620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ARCVE_RS00630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ARCVE_RS00685	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ARCVE_RS00700	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ARCVE_RS00710	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ARCVE_RS00725	COG0589	response to stress
ARCVE_RS00750	COG0531	amino acid
ARCVE_RS00780	COG0375	protein maturation
ARCVE_RS00800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ARCVE_RS00805	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ARCVE_RS00830	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ARCVE_RS00840	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ARCVE_RS00850	COG0018	arginyl-trna synthetase
ARCVE_RS00855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ARCVE_RS00875	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ARCVE_RS00905	COG5002	protein histidine kinase activity
ARCVE_RS00910	COG3290	protein histidine kinase activity
ARCVE_RS00920	COG3290	protein histidine kinase activity
ARCVE_RS00925	COG2197	response regulator
ARCVE_RS00950	COG2860	membrane
ARCVE_RS00990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARCVE_RS01015	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ARCVE_RS01020	COG1793	dna ligase
ARCVE_RS01020	COG3285	dna ligase
ARCVE_RS01035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ARCVE_RS01050	COG0109	protoheme IX farnesyltransferase activity
ARCVE_RS01070	COG0314	molybdopterin synthase activity
ARCVE_RS01085	COG0864	Transcriptional regulator
ARCVE_RS01090	COG2088	sporulation resulting in formation of a cellular spore
ARCVE_RS01095	COG0017	Asparaginyl-tRNA synthetase
ARCVE_RS01100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ARCVE_RS01115	COG3118	belongs to the thioredoxin family
ARCVE_RS01120	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ARCVE_RS01145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ARCVE_RS01150	COG1160	GTP binding
ARCVE_RS01180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ARCVE_RS01190	COG4399	Belongs to the UPF0754 family
ARCVE_RS01195	COG0303	'Molybdopterin
ARCVE_RS01200	COG0303	'Molybdopterin
ARCVE_RS01225	COG1122	ATPase activity
ARCVE_RS01230	COG1268	BioY protein
ARCVE_RS01235	COG1522	sequence-specific DNA binding
ARCVE_RS01245	COG1131	(ABC) transporter
ARCVE_RS01275	COG1131	(ABC) transporter
ARCVE_RS01300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARCVE_RS01315	COG1683	Conserved Protein
ARCVE_RS01320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ARCVE_RS01330	COG0252	asparaginase activity
ARCVE_RS01335	COG0165	Argininosuccinate lyase
ARCVE_RS01350	COG0358	DNA primase activity
ARCVE_RS01365	COG0076	glutamate decarboxylase activity
ARCVE_RS01370	COG0746	molybdenum cofactor guanylyltransferase activity
ARCVE_RS01375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ARCVE_RS01380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ARCVE_RS01395	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ARCVE_RS01415	COG0436	Aminotransferase
ARCVE_RS01470	COG1269	ATP hydrolysis coupled proton transport
ARCVE_RS01495	COG1527	subunit (C
ARCVE_RS01505	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ARCVE_RS01510	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
ARCVE_RS01525	COG0456	acetyltransferase
ARCVE_RS01530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARCVE_RS01535	COG0428	transporter
ARCVE_RS01565	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ARCVE_RS01590	COG0857	belongs to the CobB CobQ family
ARCVE_RS01595	COG1328	CTP reductase activity
ARCVE_RS01595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ARCVE_RS01605	COG0602	queuosine metabolic process
ARCVE_RS01615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARCVE_RS01620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARCVE_RS01630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ARCVE_RS01640	COG0517	IMP dehydrogenase activity
ARCVE_RS01640	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ARCVE_RS01645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ARCVE_RS01660	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
ARCVE_RS01705	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ARCVE_RS01720	COG0840	transmembrane signaling receptor activity
ARCVE_RS01720	COG3290	protein histidine kinase activity
ARCVE_RS01755	COG0154	amidase activity
ARCVE_RS01760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ARCVE_RS01775	COG1444	tRNA N-acetyltransferase activity
ARCVE_RS01785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ARCVE_RS01795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ARCVE_RS01825	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ARCVE_RS01835	COG0489	protein tyrosine kinase activity
ARCVE_RS01845	COG1229	Formylmethanofuran dehydrogenase subunit A
ARCVE_RS01865	COG0517	IMP dehydrogenase activity
ARCVE_RS01885	COG4191	Histidine kinase
ARCVE_RS01915	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ARCVE_RS01965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ARCVE_RS01975	COG0688	phosphatidylethanolamine metabolic process
ARCVE_RS01980	COG1183	phosphatidylcholine synthase activity
ARCVE_RS02000	COG1720	tRNA m6t6A37 methyltransferase activity
ARCVE_RS02015	COG0436	Aminotransferase
ARCVE_RS02025	COG1489	DNA binding
ARCVE_RS02035	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ARCVE_RS02060	COG0012	GTP binding
ARCVE_RS02085	COG2046	Belongs to the sulfate adenylyltransferase family
ARCVE_RS02105	COG1233	COG1233 Phytoene dehydrogenase and related
ARCVE_RS02110	COG0446	pyridine nucleotide-disulphide oxidoreductase
ARCVE_RS02135	COG1830	Aldolase
ARCVE_RS02140	COG1465	3-dehydroquinate synthase
ARCVE_RS02145	COG0710	3-dehydroquinate dehydratase activity
ARCVE_RS02150	COG0077	Prephenate dehydratase
ARCVE_RS02150	COG1605	Chorismate mutase
ARCVE_RS02160	COG1131	(ABC) transporter
ARCVE_RS02165	COG0842	Transport permease protein
ARCVE_RS02180	COG2358	TRAP transporter, solute receptor (TAXI family
ARCVE_RS02195	COG2104	thiamine diphosphate biosynthetic process
ARCVE_RS02220	COG1079	Belongs to the binding-protein-dependent transport system permease family
ARCVE_RS02225	COG4603	Belongs to the binding-protein-dependent transport system permease family
ARCVE_RS02230	COG3845	ABC transporter
ARCVE_RS02235	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ARCVE_RS02240	COG1342	Belongs to the UPF0251 family
ARCVE_RS02260	COG0105	UTP biosynthetic process
ARCVE_RS02265	COG3170	Tfp pilus assembly protein FimV
ARCVE_RS02265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ARCVE_RS02285	COG2226	methyltransferase
ARCVE_RS02325	COG0535	radical SAM domain protein
ARCVE_RS02330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ARCVE_RS02485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ARCVE_RS02490	COG0113	porphobilinogen synthase activity
ARCVE_RS02495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ARCVE_RS02500	COG0181	hydroxymethylbilane synthase activity
ARCVE_RS02520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ARCVE_RS02525	COG0489	protein tyrosine kinase activity
ARCVE_RS02535	COG0531	amino acid
ARCVE_RS02540	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ARCVE_RS02545	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ARCVE_RS02550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ARCVE_RS02560	COG0501	Belongs to the peptidase M48B family
ARCVE_RS02565	COG0371	Dehydrogenase
ARCVE_RS02585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ARCVE_RS02590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ARCVE_RS02605	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ARCVE_RS02615	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ARCVE_RS02650	COG0425	Belongs to the sulfur carrier protein TusA family
ARCVE_RS02675	COG0442	prolyl-tRNA aminoacylation
ARCVE_RS02680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ARCVE_RS02720	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ARCVE_RS02730	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ARCVE_RS02780	COG0463	Glycosyl transferase, family 2
ARCVE_RS02790	COG0673	inositol 2-dehydrogenase activity
ARCVE_RS02800	COG0438	transferase activity, transferring glycosyl groups
ARCVE_RS02860	COG1793	dna ligase
ARCVE_RS02890	COG0644	oxidoreductase
ARCVE_RS02895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ARCVE_RS02905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARCVE_RS02920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ARCVE_RS02930	COG0517	IMP dehydrogenase activity
ARCVE_RS02930	COG1994	Peptidase M50
ARCVE_RS02940	COG0730	response to heat
ARCVE_RS02945	COG0473	3-isopropylmalate dehydrogenase activity
ARCVE_RS02950	COG1355	regulation of microtubule-based process
ARCVE_RS02955	COG0083	homoserine kinase activity
ARCVE_RS02965	COG1304	FMN binding
ARCVE_RS03025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ARCVE_RS03045	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ARCVE_RS03050	COG0589	response to stress
ARCVE_RS03055	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ARCVE_RS03060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ARCVE_RS03070	COG2255	four-way junction helicase activity
ARCVE_RS03075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARCVE_RS03080	COG1201	RNA secondary structure unwinding
ARCVE_RS03085	COG0446	pyridine nucleotide-disulphide oxidoreductase
ARCVE_RS03090	COG1573	uracil-dna glycosylase
ARCVE_RS03110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ARCVE_RS03115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ARCVE_RS03160	COG1592	Rubrerythrin
ARCVE_RS03160	COG1773	rubredoxin
ARCVE_RS03165	COG1271	oxidase subunit
ARCVE_RS03200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ARCVE_RS03210	COG1592	Rubrerythrin
ARCVE_RS03215	COG0450	alkyl hydroperoxide reductase
ARCVE_RS03380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ARCVE_RS03390	COG0004	ammonium transporteR
ARCVE_RS03410	COG2985	domain, Protein
ARCVE_RS03410	COG0490	domain, Protein
ARCVE_RS03415	COG0475	glutathione-regulated potassium exporter activity
ARCVE_RS03420	COG0004	ammonium transporteR
ARCVE_RS03430	COG0426	domain, Protein
ARCVE_RS03435	COG3842	ATPase activity
ARCVE_RS03440	COG0519	Catalyzes the synthesis of GMP from XMP
ARCVE_RS03440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ARCVE_RS03445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARCVE_RS03450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARCVE_RS03475	COG0393	Putative heavy-metal-binding
ARCVE_RS03490	COG0438	transferase activity, transferring glycosyl groups
ARCVE_RS03515	COG1234	tRNA 3'-trailer cleavage
ARCVE_RS03520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ARCVE_RS03535	COG0437	4 iron, 4 sulfur cluster binding
ARCVE_RS03540	COG0243	molybdopterin cofactor binding
ARCVE_RS03540	COG3383	formate dehydrogenase (NAD+) activity
ARCVE_RS03560	COG0358	DNA primase activity
ARCVE_RS03620	COG1598	PFAM Uncharacterised protein family UPF0150
ARCVE_RS03670	COG0525	valine-tRNA ligase activity
ARCVE_RS03675	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARCVE_RS03685	COG1254	Belongs to the acylphosphatase family
ARCVE_RS03710	COG0569	domain protein
ARCVE_RS03715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ARCVE_RS03735	COG0343	queuine tRNA-ribosyltransferase activity
ARCVE_RS03765	COG1181	Belongs to the D-alanine--D-alanine ligase family
ARCVE_RS03775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ARCVE_RS03780	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ARCVE_RS03790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ARCVE_RS03795	COG1203	CRISPR-associated helicase, Cas3
ARCVE_RS03820	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ARCVE_RS03825	COG1518	maintenance of DNA repeat elements
ARCVE_RS03840	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ARCVE_RS03860	COG1850	ribulose-bisphosphate carboxylase activity
ARCVE_RS03875	COG0528	UMP kinase activity
ARCVE_RS03900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ARCVE_RS03905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ARCVE_RS03910	COG1013	pyruvate-flavodoxin oxidoreductase activity
ARCVE_RS03915	COG0674	pyruvate-flavodoxin oxidoreductase activity
ARCVE_RS03930	COG0493	'glutamate synthase
ARCVE_RS03930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ARCVE_RS03950	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ARCVE_RS03955	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ARCVE_RS03965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARCVE_RS03995	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ARCVE_RS04035	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ARCVE_RS04040	COG1940	carbohydrate kinase activity
ARCVE_RS04055	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ARCVE_RS04095	COG0310	cobalt ion transport
ARCVE_RS04105	COG3335	DDE superfamily endonuclease
ARCVE_RS04165	COG0539	negative regulation of cytoplasmic translation
ARCVE_RS04190	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ARCVE_RS04195	COG0515	serine threonine protein kinase
ARCVE_RS04240	COG0758	DNA mediated transformation
ARCVE_RS04255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ARCVE_RS04260	COG0704	Plays a role in the regulation of phosphate uptake
ARCVE_RS04270	COG0573	inorganic phosphate transmembrane transporter activity
ARCVE_RS04275	COG0573	inorganic phosphate transmembrane transporter activity
ARCVE_RS04280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ARCVE_RS04290	COG1335	isochorismatase
ARCVE_RS04375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARCVE_RS04395	COG0765	amino acid transport
ARCVE_RS04400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARCVE_RS04450	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ARCVE_RS04465	COG1980	fructose-bisphosphate aldolase activity
ARCVE_RS04470	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ARCVE_RS04480	COG1110	DNA topoisomerase II activity
ARCVE_RS04520	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ARCVE_RS04530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ARCVE_RS04535	COG0284	orotidine-5'-phosphate decarboxylase activity
ARCVE_RS04540	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ARCVE_RS04545	COG1363	Peptidase, m42
ARCVE_RS04565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ARCVE_RS04570	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ARCVE_RS04570	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ARCVE_RS04580	COG1227	inorganic diphosphatase activity
ARCVE_RS04585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ARCVE_RS04585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ARCVE_RS04590	COG1546	Belongs to the CinA family
ARCVE_RS04590	COG1058	Belongs to the CinA family
ARCVE_RS04655	COG0535	radical SAM domain protein
ARCVE_RS04665	COG0081	regulation of translation
ARCVE_RS04670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ARCVE_RS04710	COG0720	synthase
ARCVE_RS04715	COG0602	queuosine metabolic process
ARCVE_RS04720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ARCVE_RS04735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ARCVE_RS04735	COG0519	Catalyzes the synthesis of GMP from XMP
ARCVE_RS04745	COG1136	(ABC) transporter
ARCVE_RS04755	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ARCVE_RS04765	COG0201	protein transport
ARCVE_RS04780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ARCVE_RS04800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ARCVE_RS04805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ARCVE_RS04815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ARCVE_RS04825	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ARCVE_RS04830	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ARCVE_RS04835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ARCVE_RS04845	COG0255	Belongs to the universal ribosomal protein uL29 family
ARCVE_RS04850	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ARCVE_RS04855	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ARCVE_RS04860	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ARCVE_RS04865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ARCVE_RS04870	COG0089	rRNA binding
ARCVE_RS04895	COG0066	3-isopropylmalate dehydratase activity
ARCVE_RS04910	COG0215	cysteine-tRNA ligase activity
ARCVE_RS04920	COG0383	alpha-mannosidase activity
ARCVE_RS04925	COG3769	mannosylglycerate metabolic process
ARCVE_RS04945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARCVE_RS04955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ARCVE_RS04960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ARCVE_RS04975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ARCVE_RS05045	COG0529	Catalyzes the synthesis of activated sulfate
ARCVE_RS05080	COG2264	protein methyltransferase activity
ARCVE_RS05095	COG3118	belongs to the thioredoxin family
ARCVE_RS05110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ARCVE_RS05115	COG1836	PFAM Integral membrane protein DUF92
ARCVE_RS05125	COG1185	polyribonucleotide nucleotidyltransferase activity
ARCVE_RS05140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ARCVE_RS05145	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
ARCVE_RS05165	COG0583	DNA-binding transcription factor activity
ARCVE_RS05170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARCVE_RS05220	COG1185	polyribonucleotide nucleotidyltransferase activity
ARCVE_RS05230	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ARCVE_RS05280	COG1592	Rubrerythrin
ARCVE_RS05300	COG0124	histidyl-tRNA synthetase
ARCVE_RS05305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ARCVE_RS05310	COG0051	transcription antitermination factor activity, RNA binding
ARCVE_RS05315	COG1234	tRNA 3'-trailer cleavage
ARCVE_RS05320	COG0436	Aminotransferase
ARCVE_RS05325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ARCVE_RS05340	COG0560	Phosphoserine phosphatase
ARCVE_RS05340	COG3830	Belongs to the UPF0237 family
ARCVE_RS05360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ARCVE_RS05375	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ARCVE_RS05395	COG4109	DRTGG domain
ARCVE_RS05405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ARCVE_RS05435	COG1073	alpha beta
ARCVE_RS05440	COG0563	adenylate kinase activity
ARCVE_RS05445	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ARCVE_RS05450	COG0402	S-adenosylhomocysteine deaminase activity
ARCVE_RS05460	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ARCVE_RS05470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARCVE_RS05510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ARCVE_RS05560	COG1229	Formylmethanofuran dehydrogenase subunit A
ARCVE_RS05630	COG0470	DNA polymerase III
ARCVE_RS05630	COG1067	ATP-dependent peptidase activity
ARCVE_RS05655	COG0402	S-adenosylhomocysteine deaminase activity
ARCVE_RS05665	COG0540	Belongs to the ATCase OTCase family
ARCVE_RS05670	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ARCVE_RS05675	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ARCVE_RS05685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARCVE_RS05695	COG0668	transmembrane transport
ARCVE_RS05705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARCVE_RS05710	COG1305	Transglutaminase-like
ARCVE_RS05720	COG0714	Associated with various cellular activities
ARCVE_RS05740	COG1773	rubredoxin
ARCVE_RS05765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ARCVE_RS05775	COG1213	nucleotidyl transferase
ARCVE_RS05775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ARCVE_RS05780	COG1899	peptidyl-lysine modification to peptidyl-hypusine
ARCVE_RS05785	COG1945	arginine decarboxylase activity
ARCVE_RS05795	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ARCVE_RS05805	COG1763	Mo-molybdopterin cofactor biosynthetic process
ARCVE_RS05810	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ARCVE_RS05815	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ARCVE_RS05825	COG1830	Aldolase
ARCVE_RS05850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ARCVE_RS05855	COG0047	phosphoribosylformylglycinamidine synthase activity
ARCVE_RS05865	COG2855	membrane
ARCVE_RS05870	COG5002	protein histidine kinase activity
ARCVE_RS05870	COG3447	MASE1 domain protein
ARCVE_RS05870	COG5001	Diguanylate cyclase
ARCVE_RS05875	COG2855	membrane
ARCVE_RS05885	COG0535	radical SAM domain protein
ARCVE_RS05895	COG2855	membrane
ARCVE_RS05905	COG2855	membrane
ARCVE_RS05920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARCVE_RS05940	COG0561	phosphatase activity
ARCVE_RS05960	COG0109	protoheme IX farnesyltransferase activity
ARCVE_RS05980	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ARCVE_RS05985	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
ARCVE_RS06010	COG0674	pyruvate-flavodoxin oxidoreductase activity
ARCVE_RS06015	COG1013	pyruvate-flavodoxin oxidoreductase activity
ARCVE_RS06020	COG0483	inositol monophosphate 1-phosphatase activity
ARCVE_RS06045	COG0010	Belongs to the arginase family
ARCVE_RS06075	COG0297	glycogen (starch) synthase activity
ARCVE_RS06115	COG0247	lactate metabolic process
ARCVE_RS06115	COG2181	nitrate reductase activity
ARCVE_RS06140	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ARCVE_RS06145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ARCVE_RS06150	COG0459	protein refolding
ARCVE_RS06155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ARCVE_RS06210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ARCVE_RS06230	COG0437	4 iron, 4 sulfur cluster binding
ARCVE_RS06260	COG0803	Belongs to the bacterial solute-binding protein 9 family
ARCVE_RS06265	COG1121	(ABC) transporter
ARCVE_RS06275	COG0066	3-isopropylmalate dehydratase activity
ARCVE_RS06280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ARCVE_RS06285	COG0009	L-threonylcarbamoyladenylate synthase
ARCVE_RS06325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ARCVE_RS06355	COG2361	Protein of unknown function DUF86
ARCVE_RS06360	COG1028	Short-chain dehydrogenase reductase Sdr
ARCVE_RS06375	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ARCVE_RS06380	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ARCVE_RS06395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ARCVE_RS06400	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ARCVE_RS06415	COG2264	protein methyltransferase activity
ARCVE_RS06455	COG0069	glutamate synthase activity
ARCVE_RS06460	COG0067	glutamate synthase
ARCVE_RS06470	COG0037	tRNA processing
ARCVE_RS06505	COG1215	transferase activity, transferring glycosyl groups
ARCVE_RS06515	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ARCVE_RS06535	COG0538	isocitrate dehydrogenase activity
ARCVE_RS06540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ARCVE_RS06565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ARCVE_RS06570	COG0482	sulfurtransferase activity
ARCVE_RS06575	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ARCVE_RS06590	COG0187	DNA topoisomerase II activity
ARCVE_RS06605	COG0367	asparagine synthase
ARCVE_RS06615	COG1335	isochorismatase
ARCVE_RS06640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ARCVE_RS06655	COG0306	phosphate transporter
ARCVE_RS06720	COG0195	Participates in both transcription termination and antitermination
ARCVE_RS06730	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ARCVE_RS06735	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ARCVE_RS06740	COG0085	RNA polymerase activity
ARCVE_RS06770	COG0129	dihydroxy-acid dehydratase activity
ARCVE_RS06795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ARCVE_RS06800	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ARCVE_RS06805	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ARCVE_RS06810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ARCVE_RS06825	COG0463	Glycosyl transferase, family 2
ARCVE_RS06845	COG1131	(ABC) transporter
ARCVE_RS06895	COG1598	PFAM Uncharacterised protein family UPF0150
ARCVE_RS06900	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ARCVE_RS06905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ARCVE_RS06915	COG2078	PFAM AMMECR1 domain protein
ARCVE_RS06940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ARCVE_RS06950	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ARCVE_RS06965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ARCVE_RS06975	COG1196	nuclear chromosome segregation
ARCVE_RS07000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ARCVE_RS07005	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ARCVE_RS07010	COG4451	ribulose bisphosphate carboxylase, small
ARCVE_RS07010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ARCVE_RS07020	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ARCVE_RS07030	COG0149	triose-phosphate isomerase activity
ARCVE_RS07035	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
ARCVE_RS07050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ARCVE_RS07050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ARCVE_RS07070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ARCVE_RS07080	COG0440	acetolactate synthase activity
ARCVE_RS07145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ARCVE_RS07160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ARCVE_RS07165	COG1213	nucleotidyl transferase
ARCVE_RS07165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ARCVE_RS07175	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ARCVE_RS07205	COG0301	tRNA thio-modification
ARCVE_RS07215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ARCVE_RS07245	COG0805	protein transport
ARCVE_RS07250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ARCVE_RS07270	COG0183	Belongs to the thiolase family
ARCVE_RS07275	COG2201	protein-glutamate methylesterase activity
ARCVE_RS07280	COG2201	protein-glutamate methylesterase activity
ARCVE_RS07285	COG2198	Histidine kinase
ARCVE_RS07285	COG0643	Histidine kinase
ARCVE_RS07295	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ARCVE_RS07300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ARCVE_RS07330	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ARCVE_RS07360	COG0517	IMP dehydrogenase activity
ARCVE_RS07365	COG0517	IMP dehydrogenase activity
ARCVE_RS07375	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ARCVE_RS07380	COG0301	tRNA thio-modification
ARCVE_RS07385	COG0585	pseudouridine synthase activity
ARCVE_RS07395	COG0011	TIGRFAM Protein of
ARCVE_RS07400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ARCVE_RS07420	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ARCVE_RS07450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ARCVE_RS07455	COG0312	modulator of DNA gyrase
ARCVE_RS07475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ARCVE_RS07480	COG0322	excinuclease ABC activity
ARCVE_RS07510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ARCVE_RS07520	COG0574	Belongs to the PEP-utilizing enzyme family
ARCVE_RS07520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ARCVE_RS07570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARCVE_RS07575	COG1993	acr, cog1993
ARCVE_RS07580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARCVE_RS07585	COG1522	sequence-specific DNA binding
ARCVE_RS07600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ARCVE_RS07605	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ARCVE_RS07610	COG0330	HflC and HflK could
ARCVE_RS07615	COG0439	Biotin carboxylase
ARCVE_RS07625	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ARCVE_RS07635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ARCVE_RS07640	COG1691	(AIR) carboxylase
ARCVE_RS07645	COG0569	domain protein
ARCVE_RS07670	COG0674	pyruvate-flavodoxin oxidoreductase activity
ARCVE_RS07675	COG1013	pyruvate-flavodoxin oxidoreductase activity
ARCVE_RS07690	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ARCVE_RS07730	COG0101	tRNA pseudouridine synthase activity
ARCVE_RS07740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ARCVE_RS07745	COG1120	ATPase activity
ARCVE_RS07765	COG2181	nitrate reductase activity
ARCVE_RS07765	COG0247	lactate metabolic process
ARCVE_RS07795	COG3259	Nickel-dependent hydrogenase
ARCVE_RS07815	COG0459	protein refolding
ARCVE_RS07830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ARCVE_RS07865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ARCVE_RS07875	COG0460	homoserine dehydrogenase
ARCVE_RS07890	COG0200	Binds to the 23S rRNA
ARCVE_RS07900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ARCVE_RS07920	COG0148	phosphopyruvate hydratase activity
ARCVE_RS07925	COG0052	Belongs to the universal ribosomal protein uS2 family
ARCVE_RS07930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ARCVE_RS07950	COG3547	Transposase (IS116 IS110 IS902 family)
ARCVE_RS07960	COG1185	polyribonucleotide nucleotidyltransferase activity
ARCVE_RS07970	COG0489	protein tyrosine kinase activity
ARCVE_RS07980	COG0489	protein tyrosine kinase activity
ARCVE_RS07995	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ARCVE_RS08000	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ARCVE_RS08015	COG0517	IMP dehydrogenase activity
ARCVE_RS08015	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ARCVE_RS08020	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ARCVE_RS08030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ARCVE_RS08035	COG1891	lyase activity
ARCVE_RS08050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ARCVE_RS08055	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ARCVE_RS08060	COG0157	Belongs to the NadC ModD family
ARCVE_RS08090	COG0805	protein transport
ARCVE_RS08140	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ARCVE_RS08145	COG0444	Belongs to the ABC transporter superfamily
ARCVE_RS08160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ARCVE_RS08170	COG0747	negative chemotaxis
ARCVE_RS08175	COG2226	methyltransferase
ARCVE_RS08205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ARCVE_RS08210	COG4607	ABC-type enterochelin transport system periplasmic component
ARCVE_RS08250	COG1515	deoxyribonuclease V activity
ARCVE_RS08255	COG1321	iron dependent repressor
ARCVE_RS08280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ARCVE_RS08295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ARCVE_RS08300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ARCVE_RS08325	COG1454	alcohol dehydrogenase
ARCVE_RS08330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ARCVE_RS08410	COG1797	cobyrinic acid a,c-diamide synthase activity
ARCVE_RS08415	COG0247	lactate metabolic process
ARCVE_RS08450	COG0037	tRNA processing
ARCVE_RS08465	COG2264	protein methyltransferase activity
ARCVE_RS08500	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ARCVE_RS08520	COG0531	amino acid
ARCVE_RS08530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ARCVE_RS08540	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ARCVE_RS08540	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ARCVE_RS08545	COG0163	prenyltransferase activity
ARCVE_RS08550	COG0126	phosphoglycerate kinase activity
ARCVE_RS08560	COG0546	phosphoglycolate phosphatase activity
ARCVE_RS08570	COG0434	BtpA family
ARCVE_RS08585	COG0697	spore germination
ARCVE_RS08610	COG1131	(ABC) transporter
ARCVE_RS08625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ARCVE_RS08650	COG1598	PFAM Uncharacterised protein family UPF0150
ARCVE_RS08660	COG0719	Fe-S assembly protein
ARCVE_RS08690	COG0725	ABC transporter, periplasmic molybdate-binding protein
ARCVE_RS08700	COG3842	ATPase activity
ARCVE_RS08705	COG2005	Transcriptional regulator
ARCVE_RS08730	COG2095	MarC family integral membrane protein
ARCVE_RS08740	COG0513	Belongs to the DEAD box helicase family
ARCVE_RS08790	COG0552	protein localization to endoplasmic reticulum
ARCVE_RS08810	COG0733	neurotransmitter:sodium symporter activity
ARCVE_RS08820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ARCVE_RS08820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ARCVE_RS08850	COG1492	cobalamin metabolic process
ARCVE_RS08880	COG0131	Imidazoleglycerol-phosphate dehydratase
ARCVE_RS08880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ARCVE_RS08885	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ARCVE_RS08900	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ARCVE_RS08905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARCVE_RS08905	COG0301	tRNA thio-modification
ARCVE_RS08910	COG0315	cyclic pyranopterin monophosphate synthase activity
ARCVE_RS08915	COG1458	PINc domain ribonuclease
ARCVE_RS08930	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ARCVE_RS08935	COG3431	PFAM Phosphate-starvation-inducible E
ARCVE_RS08940	COG1881	PFAM PEBP family protein
ARCVE_RS08945	COG1469	GTP cyclohydrolase I activity
ARCVE_RS08975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ARCVE_RS08995	COG1122	ATPase activity
ARCVE_RS09010	COG0310	cobalt ion transport
ARCVE_RS09015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ARCVE_RS09045	COG0543	2 iron, 2 sulfur cluster binding
ARCVE_RS09050	COG0167	dihydroorotate dehydrogenase activity
ARCVE_RS09055	COG1794	racemase activity, acting on amino acids and derivatives
ARCVE_RS09060	COG1945	arginine decarboxylase activity
ARCVE_RS09065	COG0495	leucyl-tRNA aminoacylation
ARCVE_RS09095	COG2050	protein possibly involved in aromatic compounds catabolism
ARCVE_RS09110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARCVE_RS09115	COG1960	acyl-CoA dehydrogenase activity
ARCVE_RS09130	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ARCVE_RS09160	COG4581	dead DEAH box helicase
ARCVE_RS09190	COG2894	cell division
ARCVE_RS09210	COG0137	argininosuccinate synthase activity
ARCVE_RS09220	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ARCVE_RS09225	COG3259	Nickel-dependent hydrogenase
ARCVE_RS09230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ARCVE_RS09240	COG1476	TRANSCRIPTIONal
ARCVE_RS09265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ARCVE_RS09265	COG0731	radical SAM domain protein
ARCVE_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
ARCVE_RS09335	COG1078	dGTPase activity
ARCVE_RS09345	COG0006	proline dipeptidase activity
ARCVE_RS09360	COG0470	DNA polymerase III
ARCVE_RS09360	COG1067	ATP-dependent peptidase activity
ARCVE_RS09385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ARCVE_RS09385	COG2146	nitrite reductase [NAD(P)H] activity
ARCVE_RS09430	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ARCVE_RS09440	COG1451	nucleotide metabolic process
ARCVE_RS09445	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ARCVE_RS09475	COG0732	type I restriction modification DNA specificity domain
ARCVE_RS09525	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ARCVE_RS09535	COG2414	aldehyde ferredoxin oxidoreductase
ARCVE_RS09540	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
ARCVE_RS09545	COG1811	Na channel or pump
ARCVE_RS09605	COG1136	(ABC) transporter
ARCVE_RS09610	COG1136	(ABC) transporter
ARCVE_RS09610	COG0577	efflux transmembrane transporter activity
ARCVE_RS09630	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ARCVE_RS09635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARCVE_RS09670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ARCVE_RS09690	COG2221	Nitrite and sulphite reductase 4Fe-4S
ARCVE_RS09695	COG2221	Nitrite and sulphite reductase 4Fe-4S
ARCVE_RS09700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ARCVE_RS09705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ARCVE_RS09715	COG1121	(ABC) transporter
ARCVE_RS09720	COG1615	UPF0182 protein
ARCVE_RS09725	COG1482	cell wall glycoprotein biosynthetic process
ARCVE_RS09755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARCVE_RS09770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ARCVE_RS09795	COG0519	Catalyzes the synthesis of GMP from XMP
ARCVE_RS09795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ARCVE_RS09835	COG4608	Belongs to the ABC transporter superfamily
ARCVE_RS09840	COG0444	Belongs to the ABC transporter superfamily
ARCVE_RS09845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ARCVE_RS09850	COG0601	transmembrane transport
ARCVE_RS09855	COG0747	negative chemotaxis
ARCVE_RS09860	COG0138	bifunctional purine biosynthesis protein purh
ARCVE_RS09865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ARCVE_RS09870	COG0589	response to stress
ARCVE_RS09885	COG0492	ferredoxin-NADP+ reductase activity
ARCVE_RS09890	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ARCVE_RS09895	COG1138	Cytochrome C-type biogenesis protein
ARCVE_RS09930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ARCVE_RS09940	COG4956	integral membrane protein (PIN domain superfamily)
ARCVE_RS09945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ARCVE_RS09945	COG0140	phosphoribosyl-ATP diphosphatase activity
ARCVE_RS09975	COG0004	ammonium transporteR
ARCVE_RS09985	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
ARCVE_RS09990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ARCVE_RS09990	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ARCVE_RS10010	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
ARCVE_RS10020	COG1213	nucleotidyl transferase
ARCVE_RS10020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ARCVE_RS10025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ARCVE_RS10035	COG0521	Mo-molybdopterin cofactor biosynthetic process
ARCVE_RS10055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ARCVE_RS10115	COG0133	tryptophan synthase activity
ARCVE_RS10120	COG0135	phosphoribosylanthranilate isomerase activity
ARCVE_RS10125	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ARCVE_RS10125	COG0512	Glutamine amidotransferase of anthranilate synthase
ARCVE_RS10140	COG0134	indole-3-glycerol-phosphate synthase activity
ARCVE_RS10165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ARCVE_RS10195	COG0183	Belongs to the thiolase family
ARCVE_RS10270	COG0572	uridine kinase
ARCVE_RS10325	COG2217	Heavy metal translocating P-type atpase
ARCVE_RS10360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ARCVE_RS10370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ARCVE_RS10380	COG1201	RNA secondary structure unwinding
ARCVE_RS10400	COG1418	mRNA catabolic process
ARCVE_RS10420	COG0372	Belongs to the citrate synthase family
ARCVE_RS10425	COG0436	Aminotransferase
ARCVE_RS10430	COG0019	diaminopimelate decarboxylase activity
ARCVE_RS10435	COG2814	Major facilitator Superfamily
ARCVE_RS10450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARCVE_RS10455	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ARCVE_RS10465	COG0543	2 iron, 2 sulfur cluster binding
ARCVE_RS10485	COG0430	RNA-3'-phosphate cyclase activity
ARCVE_RS10520	COG0419	ATPase involved in DNA repair
ARCVE_RS10540	COG0589	response to stress
ARCVE_RS10555	COG0023	Translation Initiation Factor
ARCVE_RS10560	COG4555	ABC transporter
ARCVE_RS10580	COG0442	prolyl-tRNA aminoacylation
ARCVE_RS10645	COG0504	CTP synthase activity
ARCVE_RS10650	COG2835	tetraacyldisaccharide 4'-kinase activity
ARCVE_RS10655	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ARCVE_RS10685	COG0305	Participates in initiation and elongation during chromosome replication
ARCVE_RS10685	COG1372	Participates in initiation and elongation during chromosome replication
ARCVE_RS10730	COG1378	Sugar-specific transcriptional regulator TrmB
ARCVE_RS10905	COG0384	phenazine biosynthesis protein PhzF
ARCVE_RS10925	COG4152	abc transporter atp-binding protein
ARCVE_RS11010	COG1720	tRNA m6t6A37 methyltransferase activity
ARCVE_RS11020	COG4637	Psort location Cytoplasmic, score
ARCVE_RS11065	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ARCVE_RS11100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ARCVE_RS11140	COG0463	Glycosyl transferase, family 2
ARCVE_RS11170	COG4152	abc transporter atp-binding protein