locus-tag	class	description
JRI60_RS00005	COG0445	tRNA wobble uridine modification
JRI60_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
JRI60_RS00020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JRI60_RS00030	COG1192	Involved in chromosome partitioning
JRI60_RS00035	COG1475	DNA binding
JRI60_RS00055	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JRI60_RS00060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRI60_RS00065	COG0405	Gamma-glutamyltransferase
JRI60_RS00080	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JRI60_RS00155	COG0701	Predicted permease
JRI60_RS00175	COG0437	4 iron, 4 sulfur cluster binding
JRI60_RS00210	COG1845	cytochrome c oxidase, subunit III
JRI60_RS00210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JRI60_RS00255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JRI60_RS00270	COG0625	glutathione transferase activity
JRI60_RS00345	COG1127	ABC transporter
JRI60_RS00445	COG1309	transcriptional regulator
JRI60_RS00450	COG4221	oxidoreductase activity
JRI60_RS00480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_RS00535	COG0583	DNA-binding transcription factor activity
JRI60_RS00550	COG0583	DNA-binding transcription factor activity
JRI60_RS00555	COG0667	Aldo Keto reductase
JRI60_RS00560	COG0243	molybdopterin cofactor binding
JRI60_RS00590	COG3631	Ketosteroid isomerase-related protein
JRI60_RS00595	COG0702	epimerase
JRI60_RS00615	COG1793	dna ligase
JRI60_RS00630	COG5002	protein histidine kinase activity
JRI60_RS00655	COG3850	Histidine kinase
JRI60_RS00655	COG5002	protein histidine kinase activity
JRI60_RS00700	COG2226	methyltransferase
JRI60_RS00715	COG0519	Catalyzes the synthesis of GMP from XMP
JRI60_RS00720	COG0523	cobalamin synthesis protein
JRI60_RS00725	COG1301	dicarboxylic acid transport
JRI60_RS00755	COG1335	isochorismatase
JRI60_RS00835	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JRI60_RS00840	COG4181	ATPase activity
JRI60_RS00855	COG0583	DNA-binding transcription factor activity
JRI60_RS00865	COG2764	glyoxalase bleomycin resistance protein dioxygenase
JRI60_RS00915	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JRI60_RS00925	COG0625	glutathione transferase activity
JRI60_RS00930	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JRI60_RS00970	COG1902	pentaerythritol trinitrate reductase activity
JRI60_RS00990	COG2223	nitrite transmembrane transporter activity
JRI60_RS00995	COG1349	DNA-binding transcription factor activity
JRI60_RS01000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JRI60_RS01020	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_RS01040	COG0667	Aldo Keto reductase
JRI60_RS01045	COG1733	regulation of RNA biosynthetic process
JRI60_RS01055	COG0753	catalase activity
JRI60_RS01075	COG1653	transport
JRI60_RS01135	COG3227	Zinc metalloprotease (Elastase)
JRI60_RS01170	COG2815	serine threonine protein kinase
JRI60_RS01170	COG0515	serine threonine protein kinase
JRI60_RS01185	COG3174	membrane
JRI60_RS01200	COG5464	transposase or invertase
JRI60_RS01235	COG0697	spore germination
JRI60_RS01265	COG0667	Aldo Keto reductase
JRI60_RS01270	COG3034	peptidoglycan biosynthetic process
JRI60_RS01275	COG0656	L-ascorbic acid biosynthetic process
JRI60_RS01280	COG0840	transmembrane signaling receptor activity
JRI60_RS01280	COG3290	protein histidine kinase activity
JRI60_RS01305	COG0657	acetylesterase activity
JRI60_RS01310	COG4774	siderophore transport
JRI60_RS01330	COG1819	glycosyl
JRI60_RS01335	COG0515	serine threonine protein kinase
JRI60_RS01380	COG2197	response regulator
JRI60_RS01400	COG2267	carboxylic ester hydrolase activity
JRI60_RS01415	COG0515	serine threonine protein kinase
JRI60_RS01415	COG2815	serine threonine protein kinase
JRI60_RS01425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRI60_RS01445	COG0515	serine threonine protein kinase
JRI60_RS01450	COG0423	glycine-tRNA ligase activity
JRI60_RS01460	COG1228	amidohydrolase
JRI60_RS01475	COG0483	inositol monophosphate 1-phosphatase activity
JRI60_RS01485	COG0714	Associated with various cellular activities
JRI60_RS01490	COG1569	PIN domain
JRI60_RS01495	COG3311	Transcriptional regulator
JRI60_RS01570	COG1024	Enoyl-CoA hydratase
JRI60_RS01580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JRI60_RS01585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRI60_RS01610	COG0028	Belongs to the TPP enzyme family
JRI60_RS01630	COG5002	protein histidine kinase activity
JRI60_RS01635	COG2124	cytochrome p450
JRI60_RS01650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_RS01655	COG2207	Transcriptional regulator
JRI60_RS01685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JRI60_RS01715	COG2124	cytochrome p450
JRI60_RS01735	COG1763	Mo-molybdopterin cofactor biosynthetic process
JRI60_RS01815	COG0277	FAD linked oxidase domain protein
JRI60_RS01830	COG2204	response regulator
JRI60_RS01855	COG0437	4 iron, 4 sulfur cluster binding
JRI60_RS01890	COG4221	oxidoreductase activity
JRI60_RS01900	COG1739	Uncharacterized protein family UPF0029
JRI60_RS01935	COG0506	proline dehydrogenase activity
JRI60_RS01940	COG2267	carboxylic ester hydrolase activity
JRI60_RS01960	COG3483	tryptophan 2,3-dioxygenase activity
JRI60_RS02000	COG0589	response to stress
JRI60_RS02015	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JRI60_RS02025	COG5002	protein histidine kinase activity
JRI60_RS02025	COG0784	Response regulator, receiver
JRI60_RS02030	COG3179	chitinase
JRI60_RS02060	COG0516	GMP reductase activity
JRI60_RS02060	COG0517	IMP dehydrogenase activity
JRI60_RS02065	COG2124	cytochrome p450
JRI60_RS02070	COG0003	Pfam Anion-transporting ATPase
JRI60_RS02085	COG5002	protein histidine kinase activity
JRI60_RS02095	COG0235	Class ii aldolase
JRI60_RS02100	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JRI60_RS02105	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JRI60_RS02120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JRI60_RS02150	COG1917	Cupin 2, conserved barrel domain protein
JRI60_RS02155	COG0583	DNA-binding transcription factor activity
JRI60_RS02170	COG2124	cytochrome p450
JRI60_RS02220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JRI60_RS02250	COG2843	Capsule synthesis protein
JRI60_RS02275	COG2223	nitrite transmembrane transporter activity
JRI60_RS02290	COG0625	glutathione transferase activity
JRI60_RS02300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JRI60_RS02305	COG1984	allophanate hydrolase subunit 2
JRI60_RS02320	COG1940	carbohydrate kinase activity
JRI60_RS02325	COG4213	ABC transporter substrate-binding protein
JRI60_RS02360	COG4191	Histidine kinase
JRI60_RS02405	COG0328	RNA-DNA hybrid ribonuclease activity
JRI60_RS02415	COG2130	NADP-dependent
JRI60_RS02425	COG2124	cytochrome p450
JRI60_RS02425	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JRI60_RS02430	COG2124	cytochrome p450
JRI60_RS02440	COG0737	Belongs to the 5'-nucleotidase family
JRI60_RS02460	COG0596	Alpha beta hydrolase
JRI60_RS02465	COG3290	protein histidine kinase activity
JRI60_RS02475	COG0242	peptide deformylase activity
JRI60_RS02550	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JRI60_RS02550	COG0493	'glutamate synthase
JRI60_RS02555	COG4221	oxidoreductase activity
JRI60_RS02560	COG0702	epimerase
JRI60_RS02620	COG0784	Response regulator, receiver
JRI60_RS02620	COG2205	protein histidine kinase activity
JRI60_RS02635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JRI60_RS02640	COG1404	Belongs to the peptidase S8 family
JRI60_RS02650	COG1595	DNA-templated transcription, initiation
JRI60_RS02665	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JRI60_RS02700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JRI60_RS02725	COG0456	acetyltransferase
JRI60_RS02725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JRI60_RS02735	COG2267	carboxylic ester hydrolase activity
JRI60_RS02740	COG1309	transcriptional regulator
JRI60_RS02805	COG2124	cytochrome p450
JRI60_RS02810	COG0243	molybdopterin cofactor binding
JRI60_RS02895	COG2855	membrane
JRI60_RS02920	COG1233	COG1233 Phytoene dehydrogenase and related
JRI60_RS02950	COG0784	Response regulator, receiver
JRI60_RS02955	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS02955	COG1672	PFAM Archaeal ATPase
JRI60_RS02975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS02975	COG1672	PFAM Archaeal ATPase
JRI60_RS03010	COG1278	Cold shock
JRI60_RS03015	COG2205	protein histidine kinase activity
JRI60_RS03045	COG2204	response regulator
JRI60_RS03100	COG0702	epimerase
JRI60_RS03105	COG1733	regulation of RNA biosynthetic process
JRI60_RS03120	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JRI60_RS03125	COG3852	Histidine kinase
JRI60_RS03155	COG1252	NADH dehydrogenase
JRI60_RS03160	COG1122	ATPase activity
JRI60_RS03165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JRI60_RS03170	COG1268	BioY protein
JRI60_RS03175	COG1858	cytochrome C peroxidase
JRI60_RS03185	COG2201	protein-glutamate methylesterase activity
JRI60_RS03205	COG0653	protein targeting
JRI60_RS03275	COG1056	cytidyltransferase-related domain
JRI60_RS03275	COG1051	belongs to the nudix hydrolase family
JRI60_RS03305	COG2205	protein histidine kinase activity
JRI60_RS03315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JRI60_RS03320	COG0589	response to stress
JRI60_RS03345	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JRI60_RS03345	COG0515	serine threonine protein kinase
JRI60_RS03360	COG2234	aminopeptidase activity
JRI60_RS03425	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JRI60_RS03430	COG3321	synthase
JRI60_RS03430	COG0604	alcohol dehydrogenase
JRI60_RS03435	COG1882	Formate acetyltransferase
JRI60_RS03445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JRI60_RS03450	COG3321	synthase
JRI60_RS03450	COG4221	oxidoreductase activity
JRI60_RS03450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_RS03450	COG0300	oxidoreductase activity
JRI60_RS03465	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS03475	COG2133	pyrroloquinoline quinone binding
JRI60_RS03485	COG1446	asparaginase
JRI60_RS03495	COG3118	belongs to the thioredoxin family
JRI60_RS03520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JRI60_RS03525	COG1560	Kdo2-lipid A biosynthetic process
JRI60_RS03540	COG1024	Enoyl-CoA hydratase
JRI60_RS03555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JRI60_RS03580	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JRI60_RS03590	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_RS03595	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS03610	COG1058	Belongs to the CinA family
JRI60_RS03610	COG1546	Belongs to the CinA family
JRI60_RS03655	COG0477	Major facilitator Superfamily
JRI60_RS03660	COG3852	Histidine kinase
JRI60_RS03680	COG3268	Saccharopine dehydrogenase
JRI60_RS03685	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_RS03750	COG0784	Response regulator, receiver
JRI60_RS03750	COG2205	protein histidine kinase activity
JRI60_RS03755	COG0545	Peptidyl-prolyl cis-trans isomerase
JRI60_RS03760	COG0412	Dienelactone hydrolase
JRI60_RS03770	COG0010	Belongs to the arginase family
JRI60_RS03775	COG0515	serine threonine protein kinase
JRI60_RS03855	COG4191	Histidine kinase
JRI60_RS03855	COG0784	Response regulator, receiver
JRI60_RS03870	COG5006	permease, DMT superfamily
JRI60_RS03910	COG0515	serine threonine protein kinase
JRI60_RS03940	COG5002	protein histidine kinase activity
JRI60_RS03945	COG0697	spore germination
JRI60_RS03950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRI60_RS04005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_RS04085	COG0653	protein targeting
JRI60_RS04140	COG1309	transcriptional regulator
JRI60_RS04145	COG2205	protein histidine kinase activity
JRI60_RS04145	COG2202	Pas domain
JRI60_RS04175	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JRI60_RS04180	COG0443	Heat shock 70 kDa protein
JRI60_RS04255	COG0745	RESPONSE REGULATOR receiver
JRI60_RS04320	COG0542	response to heat
JRI60_RS04335	COG1324	tolerance protein
JRI60_RS04345	COG0745	RESPONSE REGULATOR receiver
JRI60_RS04355	COG2198	Histidine kinase
JRI60_RS04355	COG0643	Histidine kinase
JRI60_RS04365	COG0840	transmembrane signaling receptor activity
JRI60_RS04370	COG0835	chemotaxis
JRI60_RS04390	COG2723	6-phospho-beta-galactosidase activity
JRI60_RS04415	COG5002	protein histidine kinase activity
JRI60_RS04420	COG2201	protein-glutamate methylesterase activity
JRI60_RS04430	COG0840	transmembrane signaling receptor activity
JRI60_RS04445	COG0835	chemotaxis
JRI60_RS04470	COG2124	cytochrome p450
JRI60_RS04495	COG4989	oxidoreductase activity
JRI60_RS04515	COG2066	Belongs to the glutaminase family
JRI60_RS04515	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JRI60_RS04600	COG0588	phosphoglycerate mutase activity
JRI60_RS04625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JRI60_RS04630	COG0135	phosphoribosylanthranilate isomerase activity
JRI60_RS04635	COG0339	signal peptide processing
JRI60_RS04650	COG3118	belongs to the thioredoxin family
JRI60_RS04670	COG0628	permease
JRI60_RS04680	COG2949	membrane
JRI60_RS04690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JRI60_RS04695	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JRI60_RS04705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JRI60_RS04710	COG2346	COG2346, Truncated hemoglobins
JRI60_RS04720	COG1959	2 iron, 2 sulfur cluster binding
JRI60_RS04745	COG1271	oxidase subunit
JRI60_RS04755	COG1022	Amp-dependent synthetase and ligase
JRI60_RS04760	COG4251	negative regulation of phosphorylation
JRI60_RS04765	COG5002	protein histidine kinase activity
JRI60_RS04770	COG1505	serine-type exopeptidase activity
JRI60_RS04775	COG0537	adenosine 5'-monophosphoramidase activity
JRI60_RS04785	COG1228	amidohydrolase
JRI60_RS04790	COG0739	heme binding
JRI60_RS04810	COG2815	serine threonine protein kinase
JRI60_RS04810	COG0515	serine threonine protein kinase
JRI60_RS04815	COG0515	serine threonine protein kinase
JRI60_RS04815	COG2815	serine threonine protein kinase
JRI60_RS04840	COG2815	serine threonine protein kinase
JRI60_RS04840	COG0515	serine threonine protein kinase
JRI60_RS04845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JRI60_RS04880	COG3852	Histidine kinase
JRI60_RS04905	COG0835	chemotaxis
JRI60_RS04915	COG2201	protein-glutamate methylesterase activity
JRI60_RS04945	COG5002	protein histidine kinase activity
JRI60_RS05010	COG2204	response regulator
JRI60_RS05070	COG2205	protein histidine kinase activity
JRI60_RS05075	COG3852	Histidine kinase
JRI60_RS05100	COG0546	phosphoglycolate phosphatase activity
JRI60_RS05110	COG4191	Histidine kinase
JRI60_RS05125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JRI60_RS05125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JRI60_RS05140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_RS05145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JRI60_RS05150	COG3781	membrane
JRI60_RS05165	COG2204	response regulator
JRI60_RS05185	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JRI60_RS05200	COG4555	ABC transporter
JRI60_RS05205	COG1668	transmembrane transport
JRI60_RS05240	COG0308	aminopeptidase N
JRI60_RS05285	COG0625	glutathione transferase activity
JRI60_RS05290	COG0583	DNA-binding transcription factor activity
JRI60_RS05320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JRI60_RS05350	COG1673	EVE domain
JRI60_RS05355	COG2378	regulation of single-species biofilm formation
JRI60_RS05375	COG2066	Belongs to the glutaminase family
JRI60_RS05380	COG2433	Pfam Transposase IS66
JRI60_RS05405	COG3321	synthase
JRI60_RS05405	COG0604	alcohol dehydrogenase
JRI60_RS05415	COG0667	Aldo Keto reductase
JRI60_RS05420	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JRI60_RS05430	COG0667	Aldo Keto reductase
JRI60_RS05450	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JRI60_RS05480	COG0515	serine threonine protein kinase
JRI60_RS05480	COG2815	serine threonine protein kinase
JRI60_RS05485	COG4977	sequence-specific DNA binding
JRI60_RS05495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JRI60_RS05505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JRI60_RS05550	COG1846	Transcriptional regulator
JRI60_RS05570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_RS05575	COG1136	(ABC) transporter
JRI60_RS05585	COG0577	efflux transmembrane transporter activity
JRI60_RS05585	COG1136	(ABC) transporter
JRI60_RS05590	COG1077	Cell shape determining protein MreB Mrl
JRI60_RS05600	COG0463	Glycosyl transferase, family 2
JRI60_RS05610	COG3239	Fatty acid desaturase
JRI60_RS05615	COG0076	glutamate decarboxylase activity
JRI60_RS05630	COG2171	N-acyltransferase activity
JRI60_RS05635	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS05635	COG1672	PFAM Archaeal ATPase
JRI60_RS05640	COG2205	protein histidine kinase activity
JRI60_RS05645	COG2264	protein methyltransferase activity
JRI60_RS05650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JRI60_RS05670	COG2154	pterin-4-alpha-carbinolamine dehydratase
JRI60_RS05675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JRI60_RS05685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRI60_RS05705	COG0577	efflux transmembrane transporter activity
JRI60_RS05715	COG5002	protein histidine kinase activity
JRI60_RS05740	COG0408	coproporphyrinogen oxidase activity
JRI60_RS05790	COG4651	solute:proton antiporter activity
JRI60_RS05790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JRI60_RS05795	COG0534	Mate efflux family protein
JRI60_RS05805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS05810	COG0025	NhaP-type Na H and K H
JRI60_RS05820	COG2133	pyrroloquinoline quinone binding
JRI60_RS05845	COG1744	ABC transporter substrate-binding protein PnrA-like
JRI60_RS05865	COG0697	spore germination
JRI60_RS05870	COG1420	regulation of RNA biosynthetic process
JRI60_RS05880	COG1597	lipid kinase activity
JRI60_RS05885	COG0546	phosphoglycolate phosphatase activity
JRI60_RS05915	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JRI60_RS05920	COG2271	Major facilitator Superfamily
JRI60_RS05925	COG1199	ATP-dependent helicase activity
JRI60_RS05945	COG1100	Small GTP-binding protein
JRI60_RS05950	COG0784	Response regulator, receiver
JRI60_RS05950	COG5002	protein histidine kinase activity
JRI60_RS05950	COG2198	Histidine kinase
JRI60_RS05955	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JRI60_RS05960	COG0840	transmembrane signaling receptor activity
JRI60_RS05965	COG0835	chemotaxis
JRI60_RS05970	COG2201	protein-glutamate methylesterase activity
JRI60_RS05975	COG2198	Histidine kinase
JRI60_RS05975	COG0643	Histidine kinase
JRI60_RS05995	COG3842	ATPase activity
JRI60_RS06010	COG3833	ABC-type maltose transport systems, permease component
JRI60_RS06030	COG0366	Alpha amylase catalytic
JRI60_RS06040	COG1691	(AIR) carboxylase
JRI60_RS06045	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JRI60_RS06090	COG4948	Mandelate Racemase Muconate Lactonizing
JRI60_RS06130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JRI60_RS06135	COG0443	Heat shock 70 kDa protein
JRI60_RS06140	COG0515	serine threonine protein kinase
JRI60_RS06200	COG4106	trans-aconitate 2-methyltransferase activity
JRI60_RS06225	COG1404	Belongs to the peptidase S8 family
JRI60_RS06235	COG0442	prolyl-tRNA aminoacylation
JRI60_RS06260	COG4969	Belongs to the N-Me-Phe pilin family
JRI60_RS06290	COG1846	Transcriptional regulator
JRI60_RS06325	COG1755	Isoprenylcysteine carboxyl methyltransferase
JRI60_RS06335	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS06365	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS06370	COG3424	synthase
JRI60_RS06385	COG0277	FAD linked oxidase domain protein
JRI60_RS06400	COG0745	RESPONSE REGULATOR receiver
JRI60_RS06415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JRI60_RS06435	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_RS06450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_RS06515	COG0714	Associated with various cellular activities
JRI60_RS06525	COG0443	Heat shock 70 kDa protein
JRI60_RS06530	COG0475	glutathione-regulated potassium exporter activity
JRI60_RS06530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JRI60_RS06555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_RS06565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_RS06590	COG1846	Transcriptional regulator
JRI60_RS06600	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JRI60_RS06605	COG4208	sulfate ABC transporter
JRI60_RS06610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JRI60_RS06620	COG0406	alpha-ribazole phosphatase activity
JRI60_RS06635	COG1555	photosystem II stabilization
JRI60_RS06635	COG1596	polysaccharide export
JRI60_RS06665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRI60_RS06705	COG0723	plastoquinol--plastocyanin reductase activity
JRI60_RS06715	COG0515	serine threonine protein kinase
JRI60_RS06720	COG1120	ATPase activity
JRI60_RS06735	COG0537	adenosine 5'-monophosphoramidase activity
JRI60_RS06745	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JRI60_RS06750	COG1660	Displays ATPase and GTPase activities
JRI60_RS06755	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRI60_RS06755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRI60_RS06760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRI60_RS06770	COG3716	PTS system mannose fructose sorbose family IID component
JRI60_RS06780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JRI60_RS06785	COG1285	pathogenesis
JRI60_RS06795	COG0306	phosphate transporter
JRI60_RS06810	COG1070	Carbohydrate kinase
JRI60_RS06815	COG0829	nickel cation binding
JRI60_RS06820	COG0831	urea catabolic process
JRI60_RS06820	COG0832	Belongs to the urease beta subunit family
JRI60_RS06825	COG0804	urea catabolic process
JRI60_RS06835	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JRI60_RS06855	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JRI60_RS06860	COG0402	S-adenosylhomocysteine deaminase activity
JRI60_RS06885	COG1022	Amp-dependent synthetase and ligase
JRI60_RS06910	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JRI60_RS06915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JRI60_RS06975	COG3012	SEC-C Motif Domain Protein
JRI60_RS06980	COG1968	undecaprenyl-diphosphatase activity
JRI60_RS06990	COG2204	response regulator
JRI60_RS06995	COG4191	Histidine kinase
JRI60_RS07055	COG1940	carbohydrate kinase activity
JRI60_RS07060	COG1744	ABC transporter substrate-binding protein PnrA-like
JRI60_RS07075	COG2205	protein histidine kinase activity
JRI60_RS07075	COG3437	response regulator, receiver
JRI60_RS07075	COG3850	Histidine kinase
JRI60_RS07075	COG4999	Histidine kinase
JRI60_RS07090	COG2124	cytochrome p450
JRI60_RS07130	COG0656	L-ascorbic acid biosynthetic process
JRI60_RS07170	COG0515	serine threonine protein kinase
JRI60_RS07170	COG2815	serine threonine protein kinase
JRI60_RS07195	COG4771	TonB-dependent receptor
JRI60_RS07215	COG0714	Associated with various cellular activities
JRI60_RS07225	COG1131	(ABC) transporter
JRI60_RS07305	COG2124	cytochrome p450
JRI60_RS07310	COG2204	response regulator
JRI60_RS07330	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_RS07335	COG0730	response to heat
JRI60_RS07365	COG1640	4-alpha-glucanotransferase
JRI60_RS07370	COG2094	Belongs to the DNA glycosylase MPG family
JRI60_RS07385	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JRI60_RS07435	COG3663	DNA glycosylase
JRI60_RS07455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JRI60_RS07465	COG0477	Major facilitator Superfamily
JRI60_RS07475	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JRI60_RS07505	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS07515	COG0420	3'-5' exonuclease activity
JRI60_RS07520	COG4717	serine-type aminopeptidase activity
JRI60_RS07525	COG2224	Isocitrate lyase
JRI60_RS07530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JRI60_RS07550	COG0114	fumarate hydratase activity
JRI60_RS07575	COG0740	serine-type endopeptidase activity
JRI60_RS07590	COG0737	Belongs to the 5'-nucleotidase family
JRI60_RS07620	COG1022	Amp-dependent synthetase and ligase
JRI60_RS07650	COG1397	ADP-ribosylglycohydrolase
JRI60_RS07670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JRI60_RS07720	COG0456	acetyltransferase
JRI60_RS07725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JRI60_RS07730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JRI60_RS07745	COG4191	Histidine kinase
JRI60_RS07765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JRI60_RS07765	COG2755	lipolytic protein G-D-S-L family
JRI60_RS07795	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JRI60_RS07810	COG0676	glucose-6-phosphate 1-epimerase activity
JRI60_RS07815	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JRI60_RS07815	COG3608	succinylglutamate desuccinylase aspartoacylase
JRI60_RS07880	COG3158	transport of potassium into the cell
JRI60_RS07940	COG3848	Pyruvate phosphate dikinase
JRI60_RS07940	COG0574	Belongs to the PEP-utilizing enzyme family
JRI60_RS08080	COG0515	serine threonine protein kinase
JRI60_RS08115	COG3142	Participates in the control of copper homeostasis
JRI60_RS08125	COG2124	cytochrome p450
JRI60_RS08135	COG0741	lytic transglycosylase activity
JRI60_RS08165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JRI60_RS08270	COG0277	FAD linked oxidase domain protein
JRI60_RS08280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JRI60_RS08320	COG3942	CHAP domain
JRI60_RS08320	COG1388	LysM domain
JRI60_RS08370	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS08390	COG1136	(ABC) transporter
JRI60_RS08390	COG0577	efflux transmembrane transporter activity
JRI60_RS08395	COG1136	(ABC) transporter
JRI60_RS08395	COG0577	efflux transmembrane transporter activity
JRI60_RS08400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_RS08410	COG0745	RESPONSE REGULATOR receiver
JRI60_RS08430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JRI60_RS08450	COG5002	protein histidine kinase activity
JRI60_RS08455	COG0745	RESPONSE REGULATOR receiver
JRI60_RS08485	COG0625	glutathione transferase activity
JRI60_RS08490	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JRI60_RS08510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JRI60_RS08525	COG0023	Translation Initiation Factor
JRI60_RS08540	COG0473	3-isopropylmalate dehydrogenase activity
JRI60_RS08560	COG0583	DNA-binding transcription factor activity
JRI60_RS08565	COG0604	alcohol dehydrogenase
JRI60_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS08565	COG3321	synthase
JRI60_RS08570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JRI60_RS08610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JRI60_RS08620	COG0583	DNA-binding transcription factor activity
JRI60_RS08650	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS08655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JRI60_RS08660	COG0438	transferase activity, transferring glycosyl groups
JRI60_RS08670	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JRI60_RS08680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JRI60_RS08700	COG0248	Ppx GppA phosphatase
JRI60_RS08705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JRI60_RS08730	COG0784	Response regulator, receiver
JRI60_RS08735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRI60_RS08745	COG0515	serine threonine protein kinase
JRI60_RS08745	COG2815	serine threonine protein kinase
JRI60_RS08755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JRI60_RS08760	COG2205	protein histidine kinase activity
JRI60_RS08770	COG0070	glutamate synthase
JRI60_RS08770	COG0069	glutamate synthase activity
JRI60_RS08770	COG0067	glutamate synthase
JRI60_RS08780	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_RS08780	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_RS08795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_RS08805	COG3394	polysaccharide catabolic process
JRI60_RS08810	COG0515	serine threonine protein kinase
JRI60_RS08825	COG0402	S-adenosylhomocysteine deaminase activity
JRI60_RS08830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JRI60_RS08835	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JRI60_RS08855	COG3590	peptidase
JRI60_RS08875	COG2204	response regulator
JRI60_RS08880	COG1215	transferase activity, transferring glycosyl groups
JRI60_RS08935	COG2723	6-phospho-beta-galactosidase activity
JRI60_RS08965	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JRI60_RS08970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JRI60_RS08975	COG0784	Response regulator, receiver
JRI60_RS08985	COG0515	serine threonine protein kinase
JRI60_RS09065	COG0582	viral genome integration into host DNA
JRI60_RS09100	COG2433	Pfam Transposase IS66
JRI60_RS09130	COG0515	serine threonine protein kinase
JRI60_RS09180	COG2815	serine threonine protein kinase
JRI60_RS09180	COG0515	serine threonine protein kinase
JRI60_RS09220	COG1999	signal sequence binding
JRI60_RS09310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JRI60_RS09330	COG3620	sequence-specific DNA binding
JRI60_RS09375	COG1845	cytochrome c oxidase, subunit III
JRI60_RS09380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JRI60_RS09385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JRI60_RS09420	COG0437	4 iron, 4 sulfur cluster binding
JRI60_RS09435	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS09450	COG0693	protein deglycase activity
JRI60_RS09455	COG2819	hydrolase of the alpha beta superfamily
JRI60_RS09470	COG0512	Glutamine amidotransferase of anthranilate synthase
JRI60_RS09480	COG2070	2-Nitropropane dioxygenase
JRI60_RS09510	COG0406	alpha-ribazole phosphatase activity
JRI60_RS09515	COG0515	serine threonine protein kinase
JRI60_RS09515	COG0457	Tetratricopeptide repeat
JRI60_RS09555	COG0535	radical SAM domain protein
JRI60_RS09565	COG0159	tryptophan synthase activity
JRI60_RS09570	COG0133	tryptophan synthase activity
JRI60_RS09575	COG0135	phosphoribosylanthranilate isomerase activity
JRI60_RS09580	COG0134	indole-3-glycerol-phosphate synthase activity
JRI60_RS09585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JRI60_RS09615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JRI60_RS09620	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JRI60_RS09665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JRI60_RS09670	COG0745	RESPONSE REGULATOR receiver
JRI60_RS09715	COG1278	Cold shock
JRI60_RS09720	COG0508	dehydrogenase complex catalyzes the overall conversion of
JRI60_RS09730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JRI60_RS09735	COG2197	response regulator
JRI60_RS09745	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JRI60_RS09760	COG2201	protein-glutamate methylesterase activity
JRI60_RS09770	COG0542	response to heat
JRI60_RS09775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JRI60_RS09795	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JRI60_RS09835	COG4191	Histidine kinase
JRI60_RS09845	COG2197	response regulator
JRI60_RS09850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JRI60_RS09855	COG0477	Major facilitator Superfamily
JRI60_RS09860	COG4191	Histidine kinase
JRI60_RS09900	COG0515	serine threonine protein kinase
JRI60_RS09900	COG2815	serine threonine protein kinase
JRI60_RS09910	COG1131	(ABC) transporter
JRI60_RS09940	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JRI60_RS09965	COG3848	Pyruvate phosphate dikinase
JRI60_RS09965	COG0574	Belongs to the PEP-utilizing enzyme family
JRI60_RS09970	COG0515	serine threonine protein kinase
JRI60_RS09970	COG2815	serine threonine protein kinase
JRI60_RS10015	COG0037	tRNA processing
JRI60_RS10045	COG0515	serine threonine protein kinase
JRI60_RS10055	COG0508	dehydrogenase complex catalyzes the overall conversion of
JRI60_RS10055	COG0596	Alpha beta hydrolase
JRI60_RS10065	COG0667	Aldo Keto reductase
JRI60_RS10090	COG1404	Belongs to the peptidase S8 family
JRI60_RS10100	COG2815	serine threonine protein kinase
JRI60_RS10100	COG0515	serine threonine protein kinase
JRI60_RS10110	COG1733	regulation of RNA biosynthetic process
JRI60_RS10115	COG0604	alcohol dehydrogenase
JRI60_RS10185	COG0515	serine threonine protein kinase
JRI60_RS10205	COG0666	response to abiotic stimulus
JRI60_RS10230	COG3876	Protein conserved in bacteria
JRI60_RS10270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JRI60_RS10320	COG1196	nuclear chromosome segregation
JRI60_RS10325	COG2326	polyphosphate kinase activity
JRI60_RS10330	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS10365	COG3220	belongs to the UPF0276 family
JRI60_RS10390	COG1331	Highly conserved protein containing a thioredoxin domain
JRI60_RS10415	COG1078	dGTPase activity
JRI60_RS10420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRI60_RS10430	COG2204	response regulator
JRI60_RS10450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JRI60_RS10455	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JRI60_RS10470	COG2096	Adenosyltransferase
JRI60_RS10475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JRI60_RS10485	COG0697	spore germination
JRI60_RS10495	COG1295	ribonuclease BN
JRI60_RS10510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JRI60_RS10525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JRI60_RS10540	COG0019	diaminopimelate decarboxylase activity
JRI60_RS10545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JRI60_RS10550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JRI60_RS10555	COG0179	Fumarylacetoacetate (FAA) hydrolase
JRI60_RS10575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JRI60_RS10585	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS10590	COG2086	electron transfer activity
JRI60_RS10660	COG0300	oxidoreductase activity
JRI60_RS10675	COG0625	glutathione transferase activity
JRI60_RS10685	COG0123	including yeast histone deacetylase and acetoin utilization protein
JRI60_RS10700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JRI60_RS10705	COG0805	protein transport
JRI60_RS10705	COG0805	protein transport
JRI60_RS10720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JRI60_RS10730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JRI60_RS10735	COG0813	purine-nucleoside phosphorylase activity
JRI60_RS10740	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_RS10745	COG0667	Aldo Keto reductase
JRI60_RS10780	COG2815	serine threonine protein kinase
JRI60_RS10780	COG0515	serine threonine protein kinase
JRI60_RS10795	COG0183	Belongs to the thiolase family
JRI60_RS10820	COG3384	dioxygenase
JRI60_RS10840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JRI60_RS10845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JRI60_RS10850	COG3620	sequence-specific DNA binding
JRI60_RS10930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_RS10935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRI60_RS10950	COG0625	glutathione transferase activity
JRI60_RS11010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_RS11015	COG1388	LysM domain
JRI60_RS11015	COG3409	Peptidoglycan-binding domain 1 protein
JRI60_RS11015	COG5632	N-Acetylmuramoyl-L-alanine amidase
JRI60_RS11035	COG2815	serine threonine protein kinase
JRI60_RS11035	COG0515	serine threonine protein kinase
JRI60_RS11045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JRI60_RS11050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JRI60_RS11055	COG0583	DNA-binding transcription factor activity
JRI60_RS11060	COG1506	peptidase
JRI60_RS11060	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_RS11075	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JRI60_RS11110	COG0367	asparagine synthase
JRI60_RS11115	COG1063	alcohol dehydrogenase
JRI60_RS11145	COG0640	Transcriptional regulator
JRI60_RS11150	COG2267	carboxylic ester hydrolase activity
JRI60_RS11155	COG0697	spore germination
JRI60_RS11210	COG2032	superoxide dismutase activity
JRI60_RS11225	COG0326	Molecular chaperone. Has ATPase activity
JRI60_RS11235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_RS11260	COG2205	protein histidine kinase activity
JRI60_RS11260	COG3437	response regulator, receiver
JRI60_RS11260	COG3850	Histidine kinase
JRI60_RS11260	COG4999	Histidine kinase
JRI60_RS11270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JRI60_RS11280	COG0531	amino acid
JRI60_RS11285	COG2264	protein methyltransferase activity
JRI60_RS11295	COG2124	cytochrome p450
JRI60_RS11305	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS11315	COG0367	asparagine synthase
JRI60_RS11320	COG0736	holo-[acyl-carrier-protein] synthase activity
JRI60_RS11325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_RS11330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_RS11340	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS11350	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JRI60_RS11385	COG1846	Transcriptional regulator
JRI60_RS11390	COG4191	Histidine kinase
JRI60_RS11400	COG2339	peptidase activity
JRI60_RS11410	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
JRI60_RS11480	COG2879	small protein
JRI60_RS11485	COG1966	Carbon starvation protein
JRI60_RS11490	COG2124	cytochrome p450
JRI60_RS11495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JRI60_RS11500	COG0277	FAD linked oxidase domain protein
JRI60_RS11535	COG0587	DNA-directed DNA polymerase activity
JRI60_RS11540	COG1024	Enoyl-CoA hydratase
JRI60_RS11545	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS11560	COG0058	SHG alpha-glucan phosphorylase activity
JRI60_RS11575	COG0739	heme binding
JRI60_RS11580	COG2719	SpoVR family
JRI60_RS11585	COG2718	Belongs to the UPF0229 family
JRI60_RS11590	COG2766	serine protein kinase
JRI60_RS11600	COG4555	ABC transporter
JRI60_RS11605	COG0784	Response regulator, receiver
JRI60_RS11605	COG2205	protein histidine kinase activity
JRI60_RS11615	COG3437	response regulator, receiver
JRI60_RS11620	COG4191	Histidine kinase
JRI60_RS11640	COG2204	response regulator
JRI60_RS11645	COG3852	Histidine kinase
JRI60_RS11660	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JRI60_RS11670	COG0583	DNA-binding transcription factor activity
JRI60_RS11675	COG1741	Belongs to the pirin family
JRI60_RS11680	COG0776	regulation of translation
JRI60_RS11700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JRI60_RS11700	COG2755	lipolytic protein G-D-S-L family
JRI60_RS11725	COG1309	transcriptional regulator
JRI60_RS11755	COG0666	response to abiotic stimulus
JRI60_RS11770	COG2815	serine threonine protein kinase
JRI60_RS11770	COG0515	serine threonine protein kinase
JRI60_RS11800	COG5002	protein histidine kinase activity
JRI60_RS11810	COG2205	protein histidine kinase activity
JRI60_RS11815	COG0745	RESPONSE REGULATOR receiver
JRI60_RS11830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JRI60_RS11880	COG1192	Involved in chromosome partitioning
JRI60_RS11900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JRI60_RS11905	COG0584	glycerophosphoryl diester phosphodiesterase
JRI60_RS11915	COG0793	Belongs to the peptidase S41A family
JRI60_RS11925	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JRI60_RS11930	COG4191	Histidine kinase
JRI60_RS11930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JRI60_RS11950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JRI60_RS12005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JRI60_RS12015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRI60_RS12025	COG1459	type II secretion system
JRI60_RS12030	COG3852	Histidine kinase
JRI60_RS12045	COG1131	(ABC) transporter
JRI60_RS12055	COG4968	Prepilin-type N-terminal cleavage methylation domain
JRI60_RS12060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JRI60_RS12065	COG4191	Histidine kinase
JRI60_RS12070	COG2204	response regulator
JRI60_RS12110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JRI60_RS12115	COG0511	ligase activity, forming carbon-carbon bonds
JRI60_RS12120	COG0439	Biotin carboxylase
JRI60_RS12130	COG3267	Type II secretory pathway component ExeA
JRI60_RS12130	COG3409	Peptidoglycan-binding domain 1 protein
JRI60_RS12185	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JRI60_RS12200	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JRI60_RS12205	COG1902	pentaerythritol trinitrate reductase activity
JRI60_RS12215	COG0248	Ppx GppA phosphatase
JRI60_RS12240	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_RS12255	COG0811	peptide transport
JRI60_RS12265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JRI60_RS12280	COG2884	Cell division ATP-binding protein ftsE
JRI60_RS12285	COG2177	Part of the ABC transporter FtsEX involved in
JRI60_RS12290	COG4942	peptidase
JRI60_RS12295	COG0673	inositol 2-dehydrogenase activity
JRI60_RS12300	COG2267	carboxylic ester hydrolase activity
JRI60_RS12305	COG0793	Belongs to the peptidase S41A family
JRI60_RS12310	COG0583	DNA-binding transcription factor activity
JRI60_RS12315	COG3118	belongs to the thioredoxin family
JRI60_RS12320	COG0024	Methionine aminopeptidase
JRI60_RS12350	COG0753	catalase activity
JRI60_RS12370	COG1181	Belongs to the D-alanine--D-alanine ligase family
JRI60_RS12375	COG1215	transferase activity, transferring glycosyl groups
JRI60_RS12400	COG0552	protein localization to endoplasmic reticulum
JRI60_RS12475	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_RS12480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JRI60_RS12490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JRI60_RS12505	COG1079	Belongs to the binding-protein-dependent transport system permease family
JRI60_RS12510	COG4603	Belongs to the binding-protein-dependent transport system permease family
JRI60_RS12515	COG3845	ABC transporter
JRI60_RS12540	COG0667	Aldo Keto reductase
JRI60_RS12550	COG0402	S-adenosylhomocysteine deaminase activity
JRI60_RS12595	COG1136	(ABC) transporter
JRI60_RS12595	COG0577	efflux transmembrane transporter activity
JRI60_RS12610	COG0515	serine threonine protein kinase
JRI60_RS12620	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_RS12625	COG5002	protein histidine kinase activity
JRI60_RS12650	COG1388	LysM domain
JRI60_RS12650	COG0791	NLP P60 protein
JRI60_RS12665	COG0668	transmembrane transport
JRI60_RS12675	COG0517	IMP dehydrogenase activity
JRI60_RS12695	COG3541	Predicted nucleotidyltransferase
JRI60_RS12735	COG0596	Alpha beta hydrolase
JRI60_RS12740	COG0714	Associated with various cellular activities
JRI60_RS12780	COG1136	(ABC) transporter
JRI60_RS12805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JRI60_RS12815	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JRI60_RS12865	COG0577	efflux transmembrane transporter activity
JRI60_RS12890	COG4669	(LipO)protein
JRI60_RS12900	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JRI60_RS12910	COG4790	Type iii secretion
JRI60_RS12915	COG1987	bacterial-type flagellum assembly
JRI60_RS12920	COG1684	flagellar biosynthetic protein fliR
JRI60_RS12925	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JRI60_RS12930	COG4789	Type iii secretion
JRI60_RS12940	COG1295	ribonuclease BN
JRI60_RS12945	COG1530	ribonuclease E activity
JRI60_RS12945	COG1530	ribonuclease E activity
JRI60_RS12955	COG1254	Belongs to the acylphosphatase family
JRI60_RS12960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JRI60_RS12965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JRI60_RS12975	COG0628	permease
JRI60_RS12985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JRI60_RS12985	COG0519	Catalyzes the synthesis of GMP from XMP
JRI60_RS13000	COG1454	alcohol dehydrogenase
JRI60_RS13045	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS13060	COG2001	Belongs to the MraZ family
JRI60_RS13070	COG0275	rRNA processing
JRI60_RS13075	COG3116	cell division
JRI60_RS13085	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JRI60_RS13090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JRI60_RS13095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JRI60_RS13100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JRI60_RS13105	COG0772	Belongs to the SEDS family
JRI60_RS13110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JRI60_RS13115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JRI60_RS13120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JRI60_RS13125	COG1181	Belongs to the D-alanine--D-alanine ligase family
JRI60_RS13130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JRI60_RS13150	COG0515	serine threonine protein kinase
JRI60_RS13150	COG2815	serine threonine protein kinase
JRI60_RS13170	COG4372	Transposase
JRI60_RS13215	COG5464	transposase or invertase
JRI60_RS13220	COG1672	PFAM Archaeal ATPase
JRI60_RS13220	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS13250	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_RS13255	COG0745	RESPONSE REGULATOR receiver
JRI60_RS13280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JRI60_RS13290	COG0439	Biotin carboxylase
JRI60_RS13295	COG0511	ligase activity, forming carbon-carbon bonds
JRI60_RS13305	COG0745	RESPONSE REGULATOR receiver
JRI60_RS13310	COG0842	Transport permease protein
JRI60_RS13310	COG1716	ATPase activity
JRI60_RS13310	COG1131	(ABC) transporter
JRI60_RS13325	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JRI60_RS13335	COG0842	Transport permease protein
JRI60_RS13350	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JRI60_RS13360	COG0667	Aldo Keto reductase
JRI60_RS13400	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JRI60_RS13480	COG1929	Belongs to the glycerate kinase type-1 family
JRI60_RS13490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JRI60_RS13505	COG3030	protein affecting phage T7 exclusion by the F plasmid
JRI60_RS13535	COG0626	cystathionine gamma-synthase activity
JRI60_RS13560	COG0477	Major facilitator Superfamily
JRI60_RS13580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JRI60_RS13585	COG0631	protein serine/threonine phosphatase activity
JRI60_RS13595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JRI60_RS13610	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JRI60_RS13615	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JRI60_RS13630	COG1428	Deoxynucleoside kinase
JRI60_RS13635	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JRI60_RS13640	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JRI60_RS13645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JRI60_RS13665	COG2199	diguanylate cyclase activity
JRI60_RS13665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JRI60_RS13685	COG0779	Required for maturation of 30S ribosomal subunits
JRI60_RS13715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JRI60_RS13725	COG1185	polyribonucleotide nucleotidyltransferase activity
JRI60_RS13730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JRI60_RS13740	COG2815	serine threonine protein kinase
JRI60_RS13740	COG0515	serine threonine protein kinase
JRI60_RS13745	COG0756	dUTP diphosphatase activity
JRI60_RS13750	COG0739	heme binding
JRI60_RS13760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JRI60_RS13780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_RS13795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_RS13830	COG0612	Peptidase, M16
JRI60_RS13910	COG1484	DNA-dependent DNA replication
JRI60_RS13920	COG4584	PFAM Integrase catalytic
JRI60_RS13925	COG1484	DNA-dependent DNA replication
JRI60_RS13930	COG4584	PFAM Integrase catalytic
JRI60_RS13985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JRI60_RS13990	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS13995	COG2815	serine threonine protein kinase
JRI60_RS13995	COG0515	serine threonine protein kinase
JRI60_RS14050	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS14055	COG2205	protein histidine kinase activity
JRI60_RS14055	COG2202	Pas domain
JRI60_RS14110	COG4566	intracellular signal transduction
JRI60_RS14115	COG4191	Histidine kinase
JRI60_RS14140	COG1741	Belongs to the pirin family
JRI60_RS14170	COG3250	beta-galactosidase activity
JRI60_RS14235	COG1764	response to oxidative stress
JRI60_RS14245	COG0596	Alpha beta hydrolase
JRI60_RS14250	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JRI60_RS14260	COG0785	Cytochrome C biogenesis protein
JRI60_RS14285	COG1309	transcriptional regulator
JRI60_RS14310	COG3344	reverse transcriptase
JRI60_RS14315	COG3290	protein histidine kinase activity
JRI60_RS14340	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_RS14350	COG0183	Belongs to the thiolase family
JRI60_RS14355	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS14360	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS14370	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS14380	COG1024	Enoyl-CoA hydratase
JRI60_RS14390	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS14400	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS14405	COG2010	Cytochrome c
JRI60_RS14430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_RS14440	COG1320	monovalent cation:proton antiporter activity
JRI60_RS14445	COG2212	antiporter activity
JRI60_RS14450	COG1863	multisubunit Na H antiporter MnhE subunit
JRI60_RS14455	COG0651	ATP synthesis coupled electron transport
JRI60_RS14460	COG1006	Multisubunit Na H antiporter MnhC subunit
JRI60_RS14465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JRI60_RS14465	COG2111	Na H antiporter
JRI60_RS14490	COG2072	flavoprotein involved in K transport
JRI60_RS14500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JRI60_RS14505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_RS14515	COG0515	serine threonine protein kinase
JRI60_RS14515	COG2815	serine threonine protein kinase
JRI60_RS14520	COG2226	methyltransferase
JRI60_RS14525	COG0789	Transcriptional regulator
JRI60_RS14540	COG2815	serine threonine protein kinase
JRI60_RS14540	COG0515	serine threonine protein kinase
JRI60_RS14555	COG5507	3-demethylubiquinone-9 3-methyltransferase
JRI60_RS14605	COG0515	serine threonine protein kinase
JRI60_RS14635	COG1573	uracil-dna glycosylase
JRI60_RS14645	COG2205	protein histidine kinase activity
JRI60_RS14650	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
JRI60_RS14655	COG0412	Dienelactone hydrolase
JRI60_RS14670	COG5002	protein histidine kinase activity
JRI60_RS14685	COG4941	Belongs to the sigma-70 factor family
JRI60_RS14690	COG3795	YCII-related domain
JRI60_RS14695	COG0501	Belongs to the peptidase M48B family
JRI60_RS14715	COG1132	(ABC) transporter
JRI60_RS14720	COG1132	(ABC) transporter
JRI60_RS14725	COG2137	regulation of response to DNA damage stimulus
JRI60_RS14755	COG2124	cytochrome p450
JRI60_RS14765	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JRI60_RS14770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JRI60_RS14775	COG1492	cobalamin metabolic process
JRI60_RS14780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JRI60_RS14785	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JRI60_RS14805	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JRI60_RS14870	COG1122	ATPase activity
JRI60_RS14885	COG0310	cobalt ion transport
JRI60_RS14905	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS14950	COG4191	Histidine kinase
JRI60_RS14960	COG2706	6-phosphogluconolactonase activity
JRI60_RS14970	COG0095	Lipoate-protein ligase
JRI60_RS14980	COG3002	Belongs to the UPF0753 family
JRI60_RS14985	COG1007	ATP synthesis coupled electron transport
JRI60_RS14995	COG0659	secondary active sulfate transmembrane transporter activity
JRI60_RS15005	COG0596	Alpha beta hydrolase
JRI60_RS15020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_RS15025	COG3227	Zinc metalloprotease (Elastase)
JRI60_RS15040	COG4953	penicillin-binding protein 1C
JRI60_RS15045	COG2373	Large extracellular alpha-helical protein
JRI60_RS15090	COG4968	Prepilin-type N-terminal cleavage methylation domain
JRI60_RS15095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JRI60_RS15120	COG0681	Belongs to the peptidase S26 family
JRI60_RS15125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS15125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_RS15170	COG0300	oxidoreductase activity
JRI60_RS15185	COG2205	protein histidine kinase activity
JRI60_RS15195	COG0531	amino acid
JRI60_RS15225	COG1454	alcohol dehydrogenase
JRI60_RS15240	COG1408	metallophosphoesterase
JRI60_RS15245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JRI60_RS15270	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JRI60_RS15280	COG0840	transmembrane signaling receptor activity
JRI60_RS15290	COG2201	protein-glutamate methylesterase activity
JRI60_RS15295	COG0745	RESPONSE REGULATOR receiver
JRI60_RS15355	COG0693	protein deglycase activity
JRI60_RS15360	COG0546	phosphoglycolate phosphatase activity
JRI60_RS15365	COG1032	radical SAM domain protein
JRI60_RS15375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JRI60_RS15385	COG3292	Two component regulator propeller
JRI60_RS15385	COG0745	RESPONSE REGULATOR receiver
JRI60_RS15385	COG2205	protein histidine kinase activity
JRI60_RS15400	COG2363	Small membrane protein
JRI60_RS15410	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_RS15410	COG1506	peptidase
JRI60_RS15425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JRI60_RS15435	COG1045	serine acetyltransferase
JRI60_RS15480	COG1362	aminopeptidase activity
JRI60_RS15495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_RS15505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JRI60_RS15520	COG0631	protein serine/threonine phosphatase activity
JRI60_RS15560	COG2815	serine threonine protein kinase
JRI60_RS15560	COG0515	serine threonine protein kinase
JRI60_RS15570	COG0076	glutamate decarboxylase activity
JRI60_RS15585	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JRI60_RS15625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JRI60_RS15655	COG1301	dicarboxylic acid transport
JRI60_RS15660	COG1047	Peptidyl-prolyl cis-trans
JRI60_RS15685	COG0488	(ABC) transporter
JRI60_RS15690	COG0488	(ABC) transporter
JRI60_RS15695	COG0513	Belongs to the DEAD box helicase family
JRI60_RS15700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JRI60_RS15710	COG1187	pseudouridine synthase activity
JRI60_RS15740	COG2373	Large extracellular alpha-helical protein
JRI60_RS15750	COG0784	Response regulator, receiver
JRI60_RS15755	COG4251	negative regulation of phosphorylation
JRI60_RS15760	COG3852	Histidine kinase
JRI60_RS15765	COG0514	ATP-dependent DNA helicase (RecQ)
JRI60_RS15775	COG0644	oxidoreductase
JRI60_RS15785	COG4953	penicillin-binding protein 1C
JRI60_RS15800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_RS15800	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JRI60_RS15810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRI60_RS15820	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS15845	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JRI60_RS15865	COG0577	efflux transmembrane transporter activity
JRI60_RS15865	COG1136	(ABC) transporter
JRI60_RS15875	COG1136	(ABC) transporter
JRI60_RS15910	COG1191	sigma factor activity
JRI60_RS15920	COG1766	The M ring may be actively involved in energy transduction
JRI60_RS15930	COG1317	bacterial-type flagellum organization
JRI60_RS15935	COG1157	protein secretion by the type III secretion system
JRI60_RS15950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JRI60_RS15950	COG1776	CheC inhibitor of MCP methylation
JRI60_RS15960	COG1338	Plays a role in the flagellum-specific transport system
JRI60_RS15965	COG1987	bacterial-type flagellum assembly
JRI60_RS15975	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JRI60_RS15980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JRI60_RS16025	COG4789	Type iii secretion
JRI60_RS16035	COG1716	ATPase activity
JRI60_RS16070	COG2815	serine threonine protein kinase
JRI60_RS16070	COG0515	serine threonine protein kinase
JRI60_RS16080	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS16085	COG1169	isochorismate synthase
JRI60_RS16090	COG1021	2,3-dihydroxybenzoate-AMP ligase
JRI60_RS16095	COG1535	isochorismatase
JRI60_RS16095	COG3433	isochorismatase activity
JRI60_RS16100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_RS16105	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JRI60_RS16120	COG0811	peptide transport
JRI60_RS16140	COG2815	serine threonine protein kinase
JRI60_RS16140	COG0515	serine threonine protein kinase
JRI60_RS16145	COG2815	serine threonine protein kinase
JRI60_RS16145	COG0515	serine threonine protein kinase
JRI60_RS16165	COG0714	Associated with various cellular activities
JRI60_RS16185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JRI60_RS16215	COG3973	AAA domain
JRI60_RS16235	COG3321	synthase
JRI60_RS16235	COG0604	alcohol dehydrogenase
JRI60_RS16235	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS16255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JRI60_RS16275	COG4585	Histidine kinase
JRI60_RS16285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JRI60_RS16290	COG0616	signal peptide processing
JRI60_RS16305	COG0187	DNA topoisomerase II activity
JRI60_RS16310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JRI60_RS16320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRI60_RS16330	COG4990	cell redox homeostasis
JRI60_RS16330	COG3591	Belongs to the peptidase S1B family
JRI60_RS16340	COG1595	DNA-templated transcription, initiation
JRI60_RS16410	COG1459	type II secretion system
JRI60_RS16415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRI60_RS16445	COG1858	cytochrome C peroxidase
JRI60_RS16475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JRI60_RS16510	COG4085	toxin activity
JRI60_RS16510	COG1525	nuclease
JRI60_RS16510	COG0737	Belongs to the 5'-nucleotidase family
JRI60_RS16515	COG3275	phosphorelay sensor kinase activity
JRI60_RS16520	COG3279	Response regulator of the LytR AlgR family
JRI60_RS16535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JRI60_RS16540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JRI60_RS16575	COG0416	fatty acid biosynthetic process
JRI60_RS16605	COG0437	4 iron, 4 sulfur cluster binding
JRI60_RS16620	COG0243	molybdopterin cofactor binding
JRI60_RS16655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JRI60_RS16665	COG0564	pseudouridine synthase activity
JRI60_RS16680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JRI60_RS16685	COG4589	Belongs to the CDS family
JRI60_RS16690	COG0750	zinc metalloprotease
JRI60_RS16695	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JRI60_RS16700	COG1214	PFAM Peptidase M22, glycoprotease
JRI60_RS16705	COG0840	transmembrane signaling receptor activity
JRI60_RS16715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JRI60_RS16735	COG0314	molybdopterin synthase activity
JRI60_RS16745	COG0750	zinc metalloprotease
JRI60_RS16770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JRI60_RS16790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JRI60_RS16790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JRI60_RS16810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JRI60_RS16830	COG0515	serine threonine protein kinase
JRI60_RS16840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JRI60_RS16845	COG0316	Belongs to the HesB IscA family
JRI60_RS16850	COG1607	acyl-coa hydrolase
JRI60_RS16860	COG0584	glycerophosphoryl diester phosphodiesterase
JRI60_RS16895	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JRI60_RS16895	COG4106	trans-aconitate 2-methyltransferase activity
JRI60_RS16905	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JRI60_RS16930	COG3104	oligopeptide transport
JRI60_RS16935	COG3104	oligopeptide transport
JRI60_RS16990	COG0596	Alpha beta hydrolase
JRI60_RS16995	COG4335	DNA alkylation repair
JRI60_RS17040	COG0625	glutathione transferase activity
JRI60_RS17045	COG0583	DNA-binding transcription factor activity
JRI60_RS17105	COG1250	3-hydroxyacyl-CoA dehydrogenase
JRI60_RS17105	COG1024	Enoyl-CoA hydratase
JRI60_RS17110	COG0183	Belongs to the thiolase family
JRI60_RS17140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS17145	COG2204	response regulator
JRI60_RS17150	COG3852	Histidine kinase
JRI60_RS17170	COG2205	protein histidine kinase activity
JRI60_RS17170	COG0745	RESPONSE REGULATOR receiver
JRI60_RS17170	COG4191	Histidine kinase
JRI60_RS17190	COG2832	Protein of unknown function (DUF454)
JRI60_RS17205	COG2943	transferase activity, transferring hexosyl groups
JRI60_RS17215	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JRI60_RS17220	COG0667	Aldo Keto reductase
JRI60_RS17260	COG0402	S-adenosylhomocysteine deaminase activity
JRI60_RS17280	COG0745	RESPONSE REGULATOR receiver
JRI60_RS17290	COG0515	serine threonine protein kinase
JRI60_RS17315	COG0515	serine threonine protein kinase
JRI60_RS17315	COG2815	serine threonine protein kinase
JRI60_RS17320	COG1396	sequence-specific DNA binding
JRI60_RS17335	COG0515	serine threonine protein kinase
JRI60_RS17385	COG2354	Protein conserved in bacteria
JRI60_RS17455	COG3940	Belongs to the glycosyl hydrolase 43 family
JRI60_RS17460	COG3940	Belongs to the glycosyl hydrolase 43 family
JRI60_RS17475	COG1069	ribulokinase activity
JRI60_RS17485	COG1879	ABC-type sugar transport system periplasmic component
JRI60_RS17490	COG1129	ABC transporter
JRI60_RS17495	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRI60_RS17500	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRI60_RS17540	COG0071	Belongs to the small heat shock protein (HSP20) family
JRI60_RS17545	COG0625	glutathione transferase activity
JRI60_RS17575	COG1595	DNA-templated transcription, initiation
JRI60_RS17580	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS17615	COG1484	DNA-dependent DNA replication
JRI60_RS17620	COG4584	PFAM Integrase catalytic
JRI60_RS17655	COG0515	serine threonine protein kinase
JRI60_RS17655	COG2815	serine threonine protein kinase
JRI60_RS17705	COG0625	glutathione transferase activity
JRI60_RS17845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS17845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_RS17860	COG4771	TonB-dependent receptor
JRI60_RS17870	COG0542	response to heat
JRI60_RS17895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JRI60_RS17905	COG0305	Participates in initiation and elongation during chromosome replication
JRI60_RS17910	COG0359	binds to the 23S rRNA
JRI60_RS17915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JRI60_RS17920	COG0360	Binds together with S18 to 16S ribosomal RNA
JRI60_RS17925	COG0193	aminoacyl-tRNA hydrolase activity
JRI60_RS17930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JRI60_RS17935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JRI60_RS17940	COG2088	sporulation resulting in formation of a cellular spore
JRI60_RS17955	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JRI60_RS17980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JRI60_RS17990	COG0745	RESPONSE REGULATOR receiver
JRI60_RS17995	COG4771	TonB-dependent receptor
JRI60_RS18010	COG2378	regulation of single-species biofilm formation
JRI60_RS18035	COG3227	Zinc metalloprotease (Elastase)
JRI60_RS18055	COG0784	Response regulator, receiver
JRI60_RS18055	COG2205	protein histidine kinase activity
JRI60_RS18060	COG3507	Belongs to the glycosyl hydrolase 43 family
JRI60_RS18065	COG2124	cytochrome p450
JRI60_RS18100	COG3507	Belongs to the glycosyl hydrolase 43 family
JRI60_RS18120	COG0300	oxidoreductase activity
JRI60_RS18125	COG1773	rubredoxin
JRI60_RS18135	COG0612	Peptidase, M16
JRI60_RS18140	COG5002	protein histidine kinase activity
JRI60_RS18165	COG1304	FMN binding
JRI60_RS18195	COG1063	alcohol dehydrogenase
JRI60_RS18200	COG0667	Aldo Keto reductase
JRI60_RS18255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JRI60_RS18285	COG0583	DNA-binding transcription factor activity
JRI60_RS18300	COG0300	oxidoreductase activity
JRI60_RS18315	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JRI60_RS18320	COG1335	isochorismatase
JRI60_RS18330	COG2124	cytochrome p450
JRI60_RS18340	COG1309	transcriptional regulator
JRI60_RS18345	COG2124	cytochrome p450
JRI60_RS18350	COG5002	protein histidine kinase activity
JRI60_RS18375	COG0633	Ferredoxin
JRI60_RS18385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JRI60_RS18390	COG0316	Belongs to the HesB IscA family
JRI60_RS18395	COG0822	iron-sulfur transferase activity
JRI60_RS18400	COG1104	cysteine desulfurase activity
JRI60_RS18420	COG2239	Acts as a magnesium transporter
JRI60_RS18470	COG2211	Major facilitator Superfamily
JRI60_RS18475	COG4232	protein-disulfide reductase activity
JRI60_RS18505	COG1653	transport
JRI60_RS18540	COG0534	Mate efflux family protein
JRI60_RS18545	COG4650	regulator
JRI60_RS18550	COG1690	Belongs to the RtcB family
JRI60_RS18555	COG0430	RNA-3'-phosphate cyclase activity
JRI60_RS18570	COG0835	chemotaxis
JRI60_RS18570	COG0784	Response regulator, receiver
JRI60_RS18575	COG0217	transcriptional regulatory protein
JRI60_RS18580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JRI60_RS18585	COG0632	four-way junction helicase activity
JRI60_RS18595	COG0189	ligase activity
JRI60_RS18610	COG0475	glutathione-regulated potassium exporter activity
JRI60_RS18615	COG0475	glutathione-regulated potassium exporter activity
JRI60_RS18620	COG1396	sequence-specific DNA binding
JRI60_RS18650	COG1063	alcohol dehydrogenase
JRI60_RS18655	COG2255	four-way junction helicase activity
JRI60_RS18665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JRI60_RS18670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_RS18670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRI60_RS18690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JRI60_RS18700	COG0730	response to heat
JRI60_RS18725	COG1396	sequence-specific DNA binding
JRI60_RS18725	COG3800	Transcriptional regulator
JRI60_RS18740	COG3220	belongs to the UPF0276 family
JRI60_RS18775	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JRI60_RS18830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JRI60_RS18835	COG2890	protein-(glutamine-N5) methyltransferase activity
JRI60_RS18840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JRI60_RS18850	COG1253	flavin adenine dinucleotide binding
JRI60_RS18870	COG2205	protein histidine kinase activity
JRI60_RS18880	COG1609	Transcriptional regulator
JRI60_RS18900	COG0583	DNA-binding transcription factor activity
JRI60_RS18910	COG1196	nuclear chromosome segregation
JRI60_RS18925	COG3829	transcription factor binding
JRI60_RS18940	COG0459	protein refolding
JRI60_RS18945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JRI60_RS18965	COG1758	RNA polymerase activity
JRI60_RS18970	COG4191	Histidine kinase
JRI60_RS18975	COG4377	Putative membrane peptidase family (DUF2324)
JRI60_RS18980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JRI60_RS18990	COG0683	leucine binding
JRI60_RS18995	COG0477	Major facilitator Superfamily
JRI60_RS19015	COG1595	DNA-templated transcription, initiation
JRI60_RS19050	COG1131	(ABC) transporter
JRI60_RS19135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JRI60_RS19165	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS19175	COG0463	Glycosyl transferase, family 2
JRI60_RS19225	COG2986	histidine ammonia-lyase
JRI60_RS19335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_RS19370	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_RS19395	COG2234	aminopeptidase activity
JRI60_RS19405	COG1253	flavin adenine dinucleotide binding
JRI60_RS19410	COG0784	Response regulator, receiver
JRI60_RS19410	COG2205	protein histidine kinase activity
JRI60_RS19410	COG5002	protein histidine kinase activity
JRI60_RS19415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JRI60_RS19425	COG0704	Plays a role in the regulation of phosphate uptake
JRI60_RS19430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JRI60_RS19435	COG0581	inorganic phosphate transmembrane transporter activity
JRI60_RS19440	COG0573	inorganic phosphate transmembrane transporter activity
JRI60_RS19445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JRI60_RS19460	COG2062	phosphohistidine phosphatase, SixA
JRI60_RS19475	COG5002	protein histidine kinase activity
JRI60_RS19480	COG0745	RESPONSE REGULATOR receiver
JRI60_RS19500	COG0668	transmembrane transport
JRI60_RS19505	COG3387	PFAM Glycoside hydrolase 15-related
JRI60_RS19510	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JRI60_RS19515	COG0416	fatty acid biosynthetic process
JRI60_RS19520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_RS19535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_RS19540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_RS19545	COG0698	ribose 5-phosphate isomerase
JRI60_RS19550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JRI60_RS19555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JRI60_RS19560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_RS19560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_RS19605	COG2885	chlorophyll binding
JRI60_RS19610	COG0596	Alpha beta hydrolase
JRI60_RS19660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRI60_RS19660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRI60_RS19665	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JRI60_RS19670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JRI60_RS19680	COG0745	RESPONSE REGULATOR receiver
JRI60_RS19685	COG0784	Response regulator, receiver
JRI60_RS19685	COG2198	Histidine kinase
JRI60_RS19685	COG0784	Response regulator, receiver
JRI60_RS19685	COG0643	Histidine kinase
JRI60_RS19685	COG0643	Histidine kinase
JRI60_RS19685	COG2198	Histidine kinase
JRI60_RS19705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JRI60_RS19710	COG2201	protein-glutamate methylesterase activity
JRI60_RS19725	COG0784	Response regulator, receiver
JRI60_RS19730	COG0667	Aldo Keto reductase
JRI60_RS19735	COG3148	PFAM DTW domain containing protein
JRI60_RS19770	COG0745	RESPONSE REGULATOR receiver
JRI60_RS19775	COG0495	leucyl-tRNA aminoacylation
JRI60_RS19795	COG3956	TIGRFAM MazG family protein
JRI60_RS19805	COG0457	Tetratricopeptide repeat
JRI60_RS19815	COG1480	7TM receptor with intracellular HD hydrolase
JRI60_RS19820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JRI60_RS19820	COG0662	Cupin 2, conserved barrel domain protein
JRI60_RS19835	COG1846	Transcriptional regulator
JRI60_RS19850	COG3275	phosphorelay sensor kinase activity
JRI60_RS19855	COG3279	Response regulator of the LytR AlgR family
JRI60_RS19885	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JRI60_RS19895	COG1136	(ABC) transporter
JRI60_RS19900	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JRI60_RS19910	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JRI60_RS19915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JRI60_RS19940	COG2095	MarC family integral membrane protein
JRI60_RS19945	COG0463	Glycosyl transferase, family 2
JRI60_RS19950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JRI60_RS19975	COG1132	(ABC) transporter
JRI60_RS19985	COG3227	Zinc metalloprotease (Elastase)
JRI60_RS19990	COG1519	Transferase
JRI60_RS20000	COG1663	tetraacyldisaccharide 4'-kinase activity
JRI60_RS20010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JRI60_RS20010	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JRI60_RS20015	COG2835	tetraacyldisaccharide 4'-kinase activity
JRI60_RS20025	COG1561	YicC-like family, N-terminal region
JRI60_RS20030	COG0194	GDP metabolic process
JRI60_RS20060	COG0515	serine threonine protein kinase
JRI60_RS20090	COG2385	sporulation resulting in formation of a cellular spore
JRI60_RS20095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JRI60_RS20100	COG0343	queuine tRNA-ribosyltransferase activity
JRI60_RS20105	COG1862	Preprotein translocase
JRI60_RS20110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JRI60_RS20115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JRI60_RS20125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JRI60_RS20125	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JRI60_RS20145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JRI60_RS20150	COG1597	lipid kinase activity
JRI60_RS20165	COG1193	negative regulation of DNA recombination
JRI60_RS20170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_RS20190	COG0714	Associated with various cellular activities
JRI60_RS20200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JRI60_RS20215	COG2030	dehydratase
JRI60_RS20225	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS20255	COG0444	Belongs to the ABC transporter superfamily
JRI60_RS20260	COG4608	Belongs to the ABC transporter superfamily
JRI60_RS20330	COG1716	ATPase activity
JRI60_RS20340	COG1570	exodeoxyribonuclease VII activity
JRI60_RS20350	COG0745	RESPONSE REGULATOR receiver
JRI60_RS20360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JRI60_RS20365	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JRI60_RS20400	COG1695	Transcriptional regulator
JRI60_RS20405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JRI60_RS20415	COG0515	serine threonine protein kinase
JRI60_RS20430	COG3387	PFAM Glycoside hydrolase 15-related
JRI60_RS20450	COG2226	methyltransferase
JRI60_RS20525	COG4771	TonB-dependent receptor
JRI60_RS20555	COG0583	DNA-binding transcription factor activity
JRI60_RS20565	COG0515	serine threonine protein kinase
JRI60_RS20570	COG0583	DNA-binding transcription factor activity
JRI60_RS20575	COG2814	Major facilitator Superfamily
JRI60_RS20680	COG0596	Alpha beta hydrolase
JRI60_RS20740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JRI60_RS20755	COG0705	Rhomboid family
JRI60_RS20765	COG0741	lytic transglycosylase activity
JRI60_RS20850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_RS20855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JRI60_RS20880	COG1295	ribonuclease BN
JRI60_RS20885	COG0488	(ABC) transporter
JRI60_RS20915	COG2815	serine threonine protein kinase
JRI60_RS20915	COG0515	serine threonine protein kinase
JRI60_RS20940	COG0343	queuine tRNA-ribosyltransferase activity
JRI60_RS20965	COG0546	phosphoglycolate phosphatase activity
JRI60_RS20965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JRI60_RS20985	COG2175	clavaminate synthase activity
JRI60_RS21005	COG0022	dehydrogenase e1 component
JRI60_RS21015	COG2208	phosphoserine phosphatase activity
JRI60_RS21015	COG2770	Histidine kinase
JRI60_RS21030	COG4771	TonB-dependent receptor
JRI60_RS21040	COG0515	serine threonine protein kinase
JRI60_RS21060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JRI60_RS21085	COG0673	inositol 2-dehydrogenase activity
JRI60_RS21125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRI60_RS21130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_RS21130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_RS21140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRI60_RS21145	COG0515	serine threonine protein kinase
JRI60_RS21170	COG0443	Heat shock 70 kDa protein
JRI60_RS21230	COG4584	PFAM Integrase catalytic
JRI60_RS21240	COG4584	PFAM Integrase catalytic
JRI60_RS21245	COG1484	DNA-dependent DNA replication
JRI60_RS21275	COG1484	DNA-dependent DNA replication
JRI60_RS21280	COG4584	PFAM Integrase catalytic
JRI60_RS21285	COG1484	DNA-dependent DNA replication
JRI60_RS21290	COG4584	PFAM Integrase catalytic
JRI60_RS21335	COG0459	protein refolding
JRI60_RS21350	COG3706	GGDEF domain
JRI60_RS21365	COG0525	valine-tRNA ligase activity
JRI60_RS21375	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
JRI60_RS21380	COG0824	Thioesterase
JRI60_RS21385	COG1494	fructose-1,6-bisphosphatase
JRI60_RS21400	COG1397	ADP-ribosylglycohydrolase
JRI60_RS21405	COG0148	phosphopyruvate hydratase activity
JRI60_RS21410	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JRI60_RS21415	COG0739	heme binding
JRI60_RS21430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JRI60_RS21435	COG5002	protein histidine kinase activity
JRI60_RS21485	COG1215	transferase activity, transferring glycosyl groups
JRI60_RS21535	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
JRI60_RS21555	COG0583	DNA-binding transcription factor activity
JRI60_RS21625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_RS21635	COG0010	Belongs to the arginase family
JRI60_RS21640	COG0604	alcohol dehydrogenase
JRI60_RS21640	COG3321	synthase
JRI60_RS21645	COG2239	Acts as a magnesium transporter
JRI60_RS21650	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JRI60_RS21655	COG4464	protein tyrosine phosphatase activity
JRI60_RS21670	COG2119	membrane
JRI60_RS21675	COG5002	protein histidine kinase activity
JRI60_RS21730	COG0631	protein serine/threonine phosphatase activity
JRI60_RS21740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JRI60_RS21745	COG1360	Flagellar Motor Protein
JRI60_RS21755	COG1573	uracil-dna glycosylase
JRI60_RS21765	COG0604	alcohol dehydrogenase
JRI60_RS21770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JRI60_RS21780	COG5012	cobalamin binding
JRI60_RS21785	COG1607	acyl-coa hydrolase
JRI60_RS21790	COG3246	L-lysine catabolic process to acetate
JRI60_RS21810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JRI60_RS21815	COG0154	amidase activity
JRI60_RS21845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRI60_RS21855	COG0596	Alpha beta hydrolase
JRI60_RS21860	COG2226	methyltransferase
JRI60_RS21885	COG0697	spore germination
JRI60_RS21895	COG1819	glycosyl
JRI60_RS21925	COG2814	Major facilitator Superfamily
JRI60_RS21940	COG1605	Chorismate mutase
JRI60_RS21940	COG0077	Prephenate dehydratase
JRI60_RS21955	COG1278	Cold shock
JRI60_RS21980	COG1063	alcohol dehydrogenase
JRI60_RS21995	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JRI60_RS22015	COG0840	transmembrane signaling receptor activity
JRI60_RS22030	COG0300	oxidoreductase activity
JRI60_RS22115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JRI60_RS22165	COG0037	tRNA processing
JRI60_RS22170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRI60_RS22175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JRI60_RS22180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JRI60_RS22185	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JRI60_RS22190	COG0736	holo-[acyl-carrier-protein] synthase activity
JRI60_RS22195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JRI60_RS22195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JRI60_RS22200	COG0802	atpase or kinase
JRI60_RS22215	COG2205	protein histidine kinase activity
JRI60_RS22215	COG2202	Pas domain
JRI60_RS22225	COG1228	amidohydrolase
JRI60_RS22230	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JRI60_RS22235	COG0137	argininosuccinate synthase activity
JRI60_RS22255	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JRI60_RS22260	COG4968	Prepilin-type N-terminal cleavage methylation domain
JRI60_RS22275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_RS22280	COG1138	Cytochrome C-type biogenesis protein
JRI60_RS22285	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JRI60_RS22295	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JRI60_RS22305	COG4133	protoheme IX ABC transporter activity
JRI60_RS22330	COG0438	transferase activity, transferring glycosyl groups
JRI60_RS22365	COG0277	FAD linked oxidase domain protein
JRI60_RS22445	COG0564	pseudouridine synthase activity
JRI60_RS22460	COG1819	glycosyl
JRI60_RS22480	COG0471	metal ion transport
JRI60_RS22495	COG3781	membrane
JRI60_RS22500	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JRI60_RS22515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_RS22550	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS22585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JRI60_RS22590	COG0598	Magnesium transport protein CorA
JRI60_RS22675	COG2937	Belongs to the GPAT DAPAT family
JRI60_RS22680	COG0018	arginyl-trna synthetase
JRI60_RS22685	COG2202	Pas domain
JRI60_RS22685	COG2205	protein histidine kinase activity
JRI60_RS22700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRI60_RS22710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JRI60_RS22715	COG0049	tRNA binding
JRI60_RS22720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JRI60_RS22725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JRI60_RS22730	COG0051	transcription antitermination factor activity, RNA binding
JRI60_RS22735	COG0088	Forms part of the polypeptide exit tunnel
JRI60_RS22740	COG0089	rRNA binding
JRI60_RS22745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JRI60_RS22750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JRI60_RS22755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JRI60_RS22760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JRI60_RS22765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JRI60_RS22770	COG0255	Belongs to the universal ribosomal protein uL29 family
JRI60_RS22775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JRI60_RS22780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JRI60_RS22785	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JRI60_RS22795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JRI60_RS22800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JRI60_RS22805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JRI60_RS22810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JRI60_RS22815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JRI60_RS22820	COG1841	ribosomal large subunit assembly
JRI60_RS22825	COG0200	Binds to the 23S rRNA
JRI60_RS22840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JRI60_RS22845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JRI60_RS22850	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JRI60_RS22855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JRI60_RS22860	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JRI60_RS22875	COG0203	ribosomal protein L17
JRI60_RS22915	COG2313	pseudouridylate synthase activity
JRI60_RS22920	COG4251	negative regulation of phosphorylation
JRI60_RS22950	COG0741	lytic transglycosylase activity
JRI60_RS22975	COG3706	GGDEF domain
JRI60_RS22990	COG3209	COG3209 Rhs family protein
JRI60_RS23000	COG4372	Transposase
JRI60_RS23020	COG3209	COG3209 Rhs family protein
JRI60_RS23040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JRI60_RS23075	COG0515	serine threonine protein kinase
JRI60_RS23090	COG2706	6-phosphogluconolactonase activity
JRI60_RS23105	COG0583	DNA-binding transcription factor activity
JRI60_RS23120	COG5002	protein histidine kinase activity
JRI60_RS23140	COG2205	protein histidine kinase activity
JRI60_RS23185	COG1716	ATPase activity
JRI60_RS23195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JRI60_RS23215	COG2205	protein histidine kinase activity
JRI60_RS23215	COG0784	Response regulator, receiver
JRI60_RS23220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JRI60_RS23235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JRI60_RS23245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JRI60_RS23255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JRI60_RS23260	COG1058	Belongs to the CinA family
JRI60_RS23260	COG1546	Belongs to the CinA family
JRI60_RS23265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS23275	COG0531	amino acid
JRI60_RS23280	COG0017	Asparaginyl-tRNA synthetase
JRI60_RS23295	COG3321	synthase
JRI60_RS23295	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS23295	COG0604	alcohol dehydrogenase
JRI60_RS23365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JRI60_RS23400	COG0179	Fumarylacetoacetate (FAA) hydrolase
JRI60_RS23460	COG0217	transcriptional regulatory protein
JRI60_RS23475	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JRI60_RS23500	COG4213	ABC transporter substrate-binding protein
JRI60_RS23510	COG4214	carbohydrate transport
JRI60_RS23525	COG1595	DNA-templated transcription, initiation
JRI60_RS23545	COG1263	PTS System
JRI60_RS23545	COG2190	(PTS) system
JRI60_RS23545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRI60_RS23550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JRI60_RS23550	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRI60_RS23555	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JRI60_RS23560	COG2188	Transcriptional regulator
JRI60_RS23565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JRI60_RS23570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JRI60_RS23575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JRI60_RS23600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JRI60_RS23625	COG0527	aspartate kinase activity
JRI60_RS23670	COG5000	phosphorelay sensor kinase activity
JRI60_RS23670	COG5002	protein histidine kinase activity
JRI60_RS23690	COG0443	Heat shock 70 kDa protein
JRI60_RS23725	COG0501	Belongs to the peptidase M48B family
JRI60_RS23735	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_RS23735	COG2146	nitrite reductase [NAD(P)H] activity
JRI60_RS23755	COG1215	transferase activity, transferring glycosyl groups
JRI60_RS23815	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_RS23820	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JRI60_RS23830	COG1388	LysM domain
JRI60_RS23830	COG0791	NLP P60 protein
JRI60_RS23860	COG3321	synthase
JRI60_RS23860	COG0604	alcohol dehydrogenase
JRI60_RS23865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_RS23870	COG0179	Fumarylacetoacetate (FAA) hydrolase
JRI60_RS23880	COG1309	transcriptional regulator
JRI60_RS23920	COG5002	protein histidine kinase activity
JRI60_RS23945	COG0617	tRNA 3'-terminal CCA addition
JRI60_RS23950	COG0827	DNA restriction-modification system
JRI60_RS23955	COG0482	sulfurtransferase activity
JRI60_RS23965	COG1482	cell wall glycoprotein biosynthetic process
JRI60_RS23990	COG0481	GTPase activity
JRI60_RS24005	COG0540	Belongs to the ATCase OTCase family
JRI60_RS24015	COG0505	Belongs to the CarA family
JRI60_RS24040	COG2124	cytochrome p450
JRI60_RS24055	COG3537	Alpha-1,2-mannosidase
JRI60_RS24105	COG2267	carboxylic ester hydrolase activity
JRI60_RS24120	COG0515	serine threonine protein kinase
JRI60_RS24145	COG2267	carboxylic ester hydrolase activity
JRI60_RS24155	COG3401	FG-GAP repeat protein
JRI60_RS24160	COG1136	(ABC) transporter
JRI60_RS24160	COG0577	efflux transmembrane transporter activity
JRI60_RS24175	COG0577	efflux transmembrane transporter activity
JRI60_RS24175	COG1136	(ABC) transporter
JRI60_RS24180	COG0577	efflux transmembrane transporter activity
JRI60_RS24180	COG1136	(ABC) transporter
JRI60_RS24195	COG4191	Histidine kinase
JRI60_RS24200	COG2204	response regulator
JRI60_RS24225	COG2909	trisaccharide binding
JRI60_RS24330	COG1022	Amp-dependent synthetase and ligase
JRI60_RS24335	COG0372	Belongs to the citrate synthase family
JRI60_RS24340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JRI60_RS24345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JRI60_RS24350	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JRI60_RS24360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JRI60_RS24360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JRI60_RS24365	COG2226	methyltransferase
JRI60_RS24370	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JRI60_RS24380	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JRI60_RS24385	COG2267	carboxylic ester hydrolase activity
JRI60_RS24390	COG1575	Belongs to the MenA family. Type 1 subfamily
JRI60_RS24395	COG4948	Mandelate Racemase Muconate Lactonizing
JRI60_RS24435	COG4106	trans-aconitate 2-methyltransferase activity
JRI60_RS24440	COG0538	isocitrate dehydrogenase activity
JRI60_RS24450	COG1053	succinate dehydrogenase
JRI60_RS24455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JRI60_RS24460	COG0045	succinate-CoA ligase (ADP-forming) activity
JRI60_RS24465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JRI60_RS24510	COG4584	PFAM Integrase catalytic
JRI60_RS24520	COG1942	4-Oxalocrotonate Tautomerase
JRI60_RS24525	COG0583	DNA-binding transcription factor activity
JRI60_RS24530	COG2814	Major facilitator Superfamily
JRI60_RS24540	COG0633	Ferredoxin
JRI60_RS24550	COG1309	transcriptional regulator
JRI60_RS24570	COG2072	flavoprotein involved in K transport
JRI60_RS24590	COG1672	PFAM Archaeal ATPase
JRI60_RS24590	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS24605	COG3590	peptidase
JRI60_RS24620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_RS24655	COG1819	glycosyl
JRI60_RS24665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JRI60_RS24670	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JRI60_RS24675	COG0228	four-way junction DNA binding
JRI60_RS24680	COG1837	Belongs to the UPF0109 family
JRI60_RS24685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JRI60_RS24690	COG0336	Belongs to the RNA methyltransferase TrmD family
JRI60_RS24695	COG0335	large ribosomal subunit rRNA binding
JRI60_RS24705	COG0792	nuclease activity
JRI60_RS24710	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JRI60_RS24725	COG2204	response regulator
JRI60_RS24740	COG0728	peptidoglycan biosynthetic process
JRI60_RS24745	COG0539	negative regulation of cytoplasmic translation
JRI60_RS24790	COG2255	four-way junction helicase activity
JRI60_RS24805	COG0702	epimerase
JRI60_RS24825	COG4191	Histidine kinase
JRI60_RS24895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JRI60_RS24915	COG0515	serine threonine protein kinase
JRI60_RS24935	COG2205	protein histidine kinase activity
JRI60_RS24945	COG2124	cytochrome p450
JRI60_RS24950	COG0840	transmembrane signaling receptor activity
JRI60_RS24960	COG2124	cytochrome p450
JRI60_RS24965	COG3852	Histidine kinase
JRI60_RS24970	COG2304	oxidoreductase activity
JRI60_RS24990	COG4294	response to UV
JRI60_RS25000	COG1278	Cold shock
JRI60_RS25010	COG0545	Peptidyl-prolyl cis-trans isomerase
JRI60_RS25030	COG0628	permease
JRI60_RS25045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JRI60_RS25055	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JRI60_RS25060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JRI60_RS25065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JRI60_RS25070	COG0072	phenylalanine-tRNA ligase activity
JRI60_RS25075	COG0776	regulation of translation
JRI60_RS25125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS25150	COG0582	viral genome integration into host DNA
JRI60_RS25180	COG1484	DNA-dependent DNA replication
JRI60_RS25185	COG4584	PFAM Integrase catalytic
JRI60_RS25190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JRI60_RS25205	COG2080	2 iron, 2 sulfur cluster binding
JRI60_RS25210	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JRI60_RS25215	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JRI60_RS25220	COG4104	PAAR repeat-containing protein
JRI60_RS25235	COG1946	Acyl-CoA thioesterase
JRI60_RS25250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JRI60_RS25255	COG1116	anion transmembrane transporter activity
JRI60_RS25280	COG1131	(ABC) transporter
JRI60_RS25305	COG0525	valine-tRNA ligase activity
JRI60_RS25360	COG2720	vancomycin resistance protein
JRI60_RS25430	COG0583	DNA-binding transcription factor activity
JRI60_RS25435	COG2249	NAD(P)H dehydrogenase (quinone) activity
JRI60_RS25440	COG0583	DNA-binding transcription factor activity
JRI60_RS25450	COG0583	DNA-binding transcription factor activity
JRI60_RS25485	COG3848	Pyruvate phosphate dikinase
JRI60_RS25485	COG0574	Belongs to the PEP-utilizing enzyme family
JRI60_RS25495	COG0726	polysaccharide deacetylase
JRI60_RS25535	COG0025	NhaP-type Na H and K H
JRI60_RS25555	COG1505	serine-type exopeptidase activity
JRI60_RS25600	COG0477	Major facilitator Superfamily
JRI60_RS25620	COG4771	TonB-dependent receptor
JRI60_RS25660	COG0513	Belongs to the DEAD box helicase family
JRI60_RS25665	COG3158	transport of potassium into the cell
JRI60_RS25670	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS25690	COG5002	protein histidine kinase activity
JRI60_RS25695	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_RS25700	COG0745	RESPONSE REGULATOR receiver
JRI60_RS25705	COG1902	pentaerythritol trinitrate reductase activity
JRI60_RS25710	COG2272	Belongs to the type-B carboxylesterase lipase family
JRI60_RS25730	COG0753	catalase activity
JRI60_RS25775	COG4266	Belongs to the allantoicase family
JRI60_RS25780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JRI60_RS25785	COG2072	flavoprotein involved in K transport
JRI60_RS25790	COG2267	carboxylic ester hydrolase activity
JRI60_RS25800	COG3537	Alpha-1,2-mannosidase
JRI60_RS25805	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JRI60_RS25810	COG1131	(ABC) transporter
JRI60_RS25845	COG1047	Peptidyl-prolyl cis-trans
JRI60_RS25850	COG1671	Belongs to the UPF0178 family
JRI60_RS25885	COG3459	Glycosyltransferase 36 associated
JRI60_RS25895	COG0366	Alpha amylase catalytic
JRI60_RS25905	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JRI60_RS25910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JRI60_RS25915	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JRI60_RS25920	COG2080	2 iron, 2 sulfur cluster binding
JRI60_RS25930	COG0515	serine threonine protein kinase
JRI60_RS25950	COG0626	cystathionine gamma-synthase activity
JRI60_RS25970	COG1672	PFAM Archaeal ATPase
JRI60_RS25970	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS25985	COG2205	protein histidine kinase activity
JRI60_RS25990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JRI60_RS26000	COG0366	Alpha amylase catalytic
JRI60_RS26005	COG0366	Alpha amylase catalytic
JRI60_RS26055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_RS26070	COG2521	methyltransferase
JRI60_RS26070	COG2136	Putative SAM-dependent methyltransferase
JRI60_RS26095	COG2197	response regulator
JRI60_RS26125	COG5002	protein histidine kinase activity
JRI60_RS26130	COG2124	cytochrome p450
JRI60_RS26135	COG0612	Peptidase, M16
JRI60_RS26145	COG0564	pseudouridine synthase activity
JRI60_RS26155	COG2814	Major facilitator Superfamily
JRI60_RS26170	COG0515	serine threonine protein kinase
JRI60_RS26185	COG0750	zinc metalloprotease
JRI60_RS26205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JRI60_RS26215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JRI60_RS26250	COG0688	phosphatidylethanolamine metabolic process
JRI60_RS26305	COG0515	serine threonine protein kinase
JRI60_RS26310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JRI60_RS26315	COG0300	oxidoreductase activity
JRI60_RS26320	COG0745	RESPONSE REGULATOR receiver
JRI60_RS26345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JRI60_RS26345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JRI60_RS26365	COG0142	geranyltranstransferase activity
JRI60_RS26370	COG1830	Aldolase
JRI60_RS26385	COG0456	acetyltransferase
JRI60_RS26390	COG0156	8-amino-7-oxononanoate synthase activity
JRI60_RS26410	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JRI60_RS26410	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JRI60_RS26420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JRI60_RS26425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JRI60_RS26440	COG2204	response regulator
JRI60_RS26460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JRI60_RS26460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JRI60_RS26465	COG2223	nitrite transmembrane transporter activity
JRI60_RS26485	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS26485	COG0204	Acyl-transferase
JRI60_RS26495	COG1070	Carbohydrate kinase
JRI60_RS26500	COG0246	Mannitol dehydrogenase
JRI60_RS26515	COG4209	transmembrane transport
JRI60_RS26525	COG2124	cytochrome p450
JRI60_RS26540	COG0288	reversible hydration of carbon dioxide
JRI60_RS26555	COG0784	Response regulator, receiver
JRI60_RS26555	COG2205	protein histidine kinase activity
JRI60_RS26560	COG0457	Tetratricopeptide repeat
JRI60_RS26575	COG1024	Enoyl-CoA hydratase
JRI60_RS26595	COG1131	(ABC) transporter
JRI60_RS26650	COG0657	acetylesterase activity
JRI60_RS26655	COG2205	protein histidine kinase activity
JRI60_RS26655	COG2202	Pas domain
JRI60_RS26670	COG0583	DNA-binding transcription factor activity
JRI60_RS26685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JRI60_RS26700	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS26715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_RS26720	COG2124	cytochrome p450
JRI60_RS26725	COG2124	cytochrome p450
JRI60_RS26730	COG1309	transcriptional regulator
JRI60_RS26795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JRI60_RS26800	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS26815	COG0571	ribonuclease III activity
JRI60_RS26825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JRI60_RS26830	COG1160	GTP binding
JRI60_RS26845	COG0494	nUDIX hydrolase
JRI60_RS26870	COG3179	chitinase
JRI60_RS26960	COG0519	Catalyzes the synthesis of GMP from XMP
JRI60_RS26960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JRI60_RS26970	COG0516	GMP reductase activity
JRI60_RS26970	COG0517	IMP dehydrogenase activity
JRI60_RS26975	COG0443	Heat shock 70 kDa protein
JRI60_RS26980	COG0586	Pfam SNARE associated Golgi protein
JRI60_RS26990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JRI60_RS26995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JRI60_RS27025	COG0720	synthase
JRI60_RS27030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JRI60_RS27035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JRI60_RS27040	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JRI60_RS27045	COG0183	Belongs to the thiolase family
JRI60_RS27060	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS27070	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS27075	COG1024	Enoyl-CoA hydratase
JRI60_RS27080	COG1250	3-hydroxyacyl-CoA dehydrogenase
JRI60_RS27095	COG0489	protein tyrosine kinase activity
JRI60_RS27120	COG0515	serine threonine protein kinase
JRI60_RS27180	COG4221	oxidoreductase activity
JRI60_RS27185	COG0339	signal peptide processing
JRI60_RS27215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JRI60_RS27220	COG0667	Aldo Keto reductase
JRI60_RS27225	COG0519	Catalyzes the synthesis of GMP from XMP
JRI60_RS27270	COG2205	protein histidine kinase activity
JRI60_RS27275	COG0745	RESPONSE REGULATOR receiver
JRI60_RS27310	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS27310	COG3321	synthase
JRI60_RS27310	COG0604	alcohol dehydrogenase
JRI60_RS27325	COG1272	protein, Hemolysin III
JRI60_RS27380	COG0542	response to heat
JRI60_RS27390	COG2124	cytochrome p450
JRI60_RS27405	COG2124	cytochrome p450
JRI60_RS27415	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS27430	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS27460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_RS27470	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS27480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_RS27490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_RS27495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JRI60_RS27505	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS27520	COG2030	dehydratase
JRI60_RS27520	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_RS27525	COG0430	RNA-3'-phosphate cyclase activity
JRI60_RS27540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS27550	COG1187	pseudouridine synthase activity
JRI60_RS27555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JRI60_RS27560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JRI60_RS27595	COG4974	Belongs to the 'phage' integrase family
JRI60_RS27600	COG0009	L-threonylcarbamoyladenylate synthase
JRI60_RS27605	COG0475	glutathione-regulated potassium exporter activity
JRI60_RS27605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JRI60_RS27630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JRI60_RS27670	COG0515	serine threonine protein kinase
JRI60_RS27680	COG2433	Pfam Transposase IS66
JRI60_RS27735	COG2433	Pfam Transposase IS66
JRI60_RS27755	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JRI60_RS27755	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JRI60_RS27760	COG0860	N-Acetylmuramoyl-L-alanine amidase
JRI60_RS27780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JRI60_RS27825	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JRI60_RS27830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_RS27840	COG0747	negative chemotaxis
JRI60_RS27845	COG0601	transmembrane transport
JRI60_RS27850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JRI60_RS27855	COG0444	Belongs to the ABC transporter superfamily
JRI60_RS27860	COG4608	Belongs to the ABC transporter superfamily
JRI60_RS27865	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_RS27890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JRI60_RS27895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JRI60_RS27910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JRI60_RS27915	COG1126	abc transporter atp-binding protein
JRI60_RS27920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JRI60_RS27930	COG3507	Belongs to the glycosyl hydrolase 43 family
JRI60_RS27930	COG3693	PFAM glycoside hydrolase, family 10
JRI60_RS27930	COG2382	esterase
JRI60_RS28010	COG0515	serine threonine protein kinase
JRI60_RS28010	COG2815	serine threonine protein kinase
JRI60_RS28025	COG0585	pseudouridine synthase activity
JRI60_RS28030	COG1595	DNA-templated transcription, initiation
JRI60_RS28060	COG0300	oxidoreductase activity
JRI60_RS28090	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS28090	COG0204	Acyl-transferase
JRI60_RS28095	COG0708	Exodeoxyribonuclease III
JRI60_RS28105	COG0667	Aldo Keto reductase
JRI60_RS28115	COG4191	Histidine kinase
JRI60_RS28135	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS28140	COG1073	alpha beta
JRI60_RS28195	COG2267	carboxylic ester hydrolase activity
JRI60_RS28220	COG0488	(ABC) transporter
JRI60_RS28330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRI60_RS28355	COG0583	DNA-binding transcription factor activity
JRI60_RS28385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JRI60_RS28400	COG0463	Glycosyl transferase, family 2
JRI60_RS28490	COG0667	Aldo Keto reductase
JRI60_RS28500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_RS28515	COG2815	serine threonine protein kinase
JRI60_RS28515	COG0515	serine threonine protein kinase
JRI60_RS28540	COG2124	cytochrome p450
JRI60_RS28550	COG2070	2-Nitropropane dioxygenase
JRI60_RS28550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JRI60_RS28555	COG3321	synthase
JRI60_RS28560	COG1024	Enoyl-CoA hydratase
JRI60_RS28565	COG1024	Enoyl-CoA hydratase
JRI60_RS28570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_RS28575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_RS28580	COG3425	synthase
JRI60_RS28585	COG3321	synthase
JRI60_RS28585	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS28585	COG4221	oxidoreductase activity
JRI60_RS28585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_RS28595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_RS28595	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS28595	COG3321	synthase
JRI60_RS28595	COG4221	oxidoreductase activity
JRI60_RS28600	COG3321	synthase
JRI60_RS28600	COG4221	oxidoreductase activity
JRI60_RS28600	COG0300	oxidoreductase activity
JRI60_RS28600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_RS28610	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JRI60_RS28615	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JRI60_RS28620	COG1438	arginine binding
JRI60_RS28625	COG0165	Argininosuccinate lyase
JRI60_RS28630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JRI60_RS28635	COG2027	D-alanyl-D-alanine carboxypeptidase
JRI60_RS28640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JRI60_RS28650	COG0436	Aminotransferase
JRI60_RS28655	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JRI60_RS28660	COG0742	ribosomal rna small subunit methyltransferase
JRI60_RS28670	COG0004	ammonium transporteR
JRI60_RS28690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JRI60_RS28695	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JRI60_RS28705	COG2311	Membrane
JRI60_RS28745	COG0726	polysaccharide deacetylase
JRI60_RS28785	COG2204	response regulator
JRI60_RS28795	COG1217	gtp-binding protein TYPA
JRI60_RS28800	COG2814	Major facilitator Superfamily
JRI60_RS28840	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JRI60_RS28850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JRI60_RS28865	COG5002	protein histidine kinase activity
JRI60_RS28945	COG0583	DNA-binding transcription factor activity
JRI60_RS28950	COG0527	aspartate kinase activity
JRI60_RS28960	COG1830	Aldolase
JRI60_RS28975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JRI60_RS28990	COG1764	response to oxidative stress
JRI60_RS29000	COG2133	pyrroloquinoline quinone binding
JRI60_RS29005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JRI60_RS29050	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JRI60_RS29090	COG1846	Transcriptional regulator
JRI60_RS29105	COG1309	transcriptional regulator
JRI60_RS29110	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS29115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JRI60_RS29145	COG0739	heme binding
JRI60_RS29145	COG1196	nuclear chromosome segregation
JRI60_RS29145	COG0741	lytic transglycosylase activity
JRI60_RS29160	COG0714	Associated with various cellular activities
JRI60_RS29175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JRI60_RS29180	COG1297	OPT oligopeptide transporter protein
JRI60_RS29215	COG0564	pseudouridine synthase activity
JRI60_RS29250	COG0741	lytic transglycosylase activity
JRI60_RS29255	COG4191	Histidine kinase
JRI60_RS29280	COG4681	YaeQ
JRI60_RS29305	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JRI60_RS29315	COG0488	(ABC) transporter
JRI60_RS29330	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JRI60_RS29335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JRI60_RS29340	COG0825	malonyl-CoA metabolic process
JRI60_RS29390	COG0443	Heat shock 70 kDa protein
JRI60_RS29415	COG0101	tRNA pseudouridine synthase activity
JRI60_RS29430	COG1606	tRNA processing
JRI60_RS29435	COG2046	Belongs to the sulfate adenylyltransferase family
JRI60_RS29435	COG0529	Catalyzes the synthesis of activated sulfate
JRI60_RS29455	COG4585	Histidine kinase
JRI60_RS29490	COG1309	transcriptional regulator
JRI60_RS29530	COG2204	response regulator
JRI60_RS29655	COG1181	Belongs to the D-alanine--D-alanine ligase family
JRI60_RS29670	COG0113	porphobilinogen synthase activity
JRI60_RS29680	COG1131	(ABC) transporter
JRI60_RS29695	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JRI60_RS29760	COG0686	Belongs to the AlaDH PNT family
JRI60_RS29765	COG1595	DNA-templated transcription, initiation
JRI60_RS29785	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JRI60_RS29790	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JRI60_RS29790	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JRI60_RS29855	COG0572	uridine kinase
JRI60_RS29925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JRI60_RS29940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRI60_RS29950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JRI60_RS29960	COG0577	efflux transmembrane transporter activity
JRI60_RS29960	COG1136	(ABC) transporter
JRI60_RS29965	COG1136	(ABC) transporter
JRI60_RS29985	COG0542	response to heat
JRI60_RS30070	COG0737	Belongs to the 5'-nucleotidase family
JRI60_RS30110	COG0583	DNA-binding transcription factor activity
JRI60_RS30125	COG2815	serine threonine protein kinase
JRI60_RS30125	COG0515	serine threonine protein kinase
JRI60_RS30135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JRI60_RS30145	COG3876	Protein conserved in bacteria
JRI60_RS30160	COG1193	negative regulation of DNA recombination
JRI60_RS30175	COG4733	cellulase activity
JRI60_RS30175	COG4447	cellulose binding
JRI60_RS30180	COG5297	Belongs to the glycosyl hydrolase family 6
JRI60_RS30180	COG4733	cellulase activity
JRI60_RS30185	COG3842	ATPase activity
JRI60_RS30195	COG1175	transmembrane transport
JRI60_RS30200	COG1653	transport
JRI60_RS30205	COG2723	6-phospho-beta-galactosidase activity
JRI60_RS30210	COG1609	Transcriptional regulator
JRI60_RS30230	COG2205	protein histidine kinase activity
JRI60_RS30265	COG2897	thiosulfate sulfurtransferase activity
JRI60_RS30270	COG0564	pseudouridine synthase activity
JRI60_RS30280	COG0557	exoribonuclease II activity
JRI60_RS30290	COG0303	'Molybdopterin
JRI60_RS30295	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRI60_RS30295	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRI60_RS30320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JRI60_RS30330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JRI60_RS30350	COG0557	exoribonuclease II activity
JRI60_RS30360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JRI60_RS30360	COG0140	phosphoribosyl-ATP diphosphatase activity
JRI60_RS30370	COG0107	imidazoleglycerol-phosphate synthase activity
JRI60_RS30375	COG0131	Imidazoleglycerol-phosphate dehydratase
JRI60_RS30380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JRI60_RS30385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JRI60_RS30395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JRI60_RS30400	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JRI60_RS30410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JRI60_RS30420	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JRI60_RS30440	COG2204	response regulator
JRI60_RS30445	COG4191	Histidine kinase
JRI60_RS30450	COG0745	RESPONSE REGULATOR receiver
JRI60_RS30450	COG4566	intracellular signal transduction
JRI60_RS30455	COG2205	protein histidine kinase activity
JRI60_RS30505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JRI60_RS30505	COG0189	ligase activity
JRI60_RS30515	COG1695	Transcriptional regulator
JRI60_RS30535	COG2072	flavoprotein involved in K transport
JRI60_RS30545	COG0657	acetylesterase activity
JRI60_RS30550	COG0386	Belongs to the glutathione peroxidase family
JRI60_RS30635	COG0515	serine threonine protein kinase
JRI60_RS30645	COG0515	serine threonine protein kinase
JRI60_RS30645	COG2815	serine threonine protein kinase
JRI60_RS30680	COG2072	flavoprotein involved in K transport
JRI60_RS30685	COG1309	transcriptional regulator
JRI60_RS30690	COG0583	DNA-binding transcription factor activity
JRI60_RS30720	COG1335	isochorismatase
JRI60_RS30735	COG2124	cytochrome p450
JRI60_RS30740	COG1846	Transcriptional regulator
JRI60_RS30755	COG0583	DNA-binding transcription factor activity
JRI60_RS30760	COG0667	Aldo Keto reductase
JRI60_RS30765	COG1064	alcohol dehydrogenase
JRI60_RS30795	COG1064	alcohol dehydrogenase
JRI60_RS30820	COG0583	DNA-binding transcription factor activity
JRI60_RS30845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JRI60_RS30865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JRI60_RS30885	COG0494	nUDIX hydrolase
JRI60_RS30900	COG3088	subunit of a heme lyase
JRI60_RS30935	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JRI60_RS30940	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JRI60_RS30945	COG0489	protein tyrosine kinase activity
JRI60_RS30970	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JRI60_RS30990	COG4221	oxidoreductase activity
JRI60_RS30995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_RS31010	COG0784	Response regulator, receiver
JRI60_RS31010	COG4191	Histidine kinase
JRI60_RS31025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JRI60_RS31035	COG0583	DNA-binding transcription factor activity
JRI60_RS31045	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
JRI60_RS31085	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JRI60_RS31120	COG0534	Mate efflux family protein
JRI60_RS31150	COG1082	Xylose isomerase domain protein TIM barrel
JRI60_RS31205	COG1595	DNA-templated transcription, initiation
JRI60_RS31235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_RS31240	COG3852	Histidine kinase
JRI60_RS31255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRI60_RS31255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_RS31260	COG2204	response regulator
JRI60_RS31265	COG3706	GGDEF domain
JRI60_RS31295	COG1131	(ABC) transporter
JRI60_RS31300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRI60_RS31300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_RS31355	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS31360	COG1024	Enoyl-CoA hydratase
JRI60_RS31360	COG1250	3-hydroxyacyl-CoA dehydrogenase
JRI60_RS31365	COG0183	Belongs to the thiolase family
JRI60_RS31390	COG0443	Heat shock 70 kDa protein
JRI60_RS31405	COG2921	Belongs to the UPF0250 family
JRI60_RS31410	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JRI60_RS31415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JRI60_RS31430	COG0583	DNA-binding transcription factor activity
JRI60_RS31435	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS31435	COG3321	synthase
JRI60_RS31435	COG0604	alcohol dehydrogenase
JRI60_RS31460	COG2226	methyltransferase
JRI60_RS31465	COG5002	protein histidine kinase activity
JRI60_RS31475	COG3384	dioxygenase
JRI60_RS31480	COG0583	DNA-binding transcription factor activity
JRI60_RS31485	COG2198	Histidine kinase
JRI60_RS31485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JRI60_RS31485	COG0784	Response regulator, receiver
JRI60_RS31485	COG2205	protein histidine kinase activity
JRI60_RS31490	COG1879	ABC-type sugar transport system periplasmic component
JRI60_RS31505	COG4104	PAAR repeat-containing protein
JRI60_RS31520	COG0457	Tetratricopeptide repeat
JRI60_RS31525	COG0436	Aminotransferase
JRI60_RS31545	COG4191	Histidine kinase
JRI60_RS31550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JRI60_RS31555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JRI60_RS31565	COG0175	sulfate reduction
JRI60_RS31570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JRI60_RS31570	COG1648	precorrin-2 dehydrogenase activity
JRI60_RS31580	COG0175	sulfate reduction
JRI60_RS31590	COG3217	Mosc domain protein beta barrel domain protein
JRI60_RS31590	COG0633	Ferredoxin
JRI60_RS31595	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS31595	COG1672	PFAM Archaeal ATPase
JRI60_RS31600	COG1295	ribonuclease BN
JRI60_RS31600	COG1959	2 iron, 2 sulfur cluster binding
JRI60_RS31615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS31620	COG0006	proline dipeptidase activity
JRI60_RS31625	COG3227	Zinc metalloprotease (Elastase)
JRI60_RS31640	COG5002	protein histidine kinase activity
JRI60_RS31645	COG0745	RESPONSE REGULATOR receiver
JRI60_RS31685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JRI60_RS31695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_RS31730	COG2197	response regulator
JRI60_RS31735	COG0071	Belongs to the small heat shock protein (HSP20) family
JRI60_RS31800	COG1131	(ABC) transporter
JRI60_RS31820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JRI60_RS31840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JRI60_RS31855	COG4221	oxidoreductase activity
JRI60_RS31855	COG3321	synthase
JRI60_RS31855	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS31855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_RS31860	COG3852	Histidine kinase
JRI60_RS31870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_RS31880	COG0484	heat shock protein binding
JRI60_RS31885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JRI60_RS31895	COG1872	DUF167
JRI60_RS31920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JRI60_RS31920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JRI60_RS31935	COG1450	Type ii and iii secretion system protein
JRI60_RS31960	COG0751	glycine-tRNA ligase activity
JRI60_RS31965	COG0752	glycyl-tRNA synthetase alpha subunit
JRI60_RS31980	COG1381	Involved in DNA repair and RecF pathway recombination
JRI60_RS32015	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JRI60_RS32020	COG0085	RNA polymerase activity
JRI60_RS32025	COG0222	ribosome binding
JRI60_RS32030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JRI60_RS32035	COG0081	regulation of translation
JRI60_RS32040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JRI60_RS32060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JRI60_RS32065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JRI60_RS32090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JRI60_RS32125	COG1643	Atp-dependent helicase
JRI60_RS32185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JRI60_RS32185	COG0047	phosphoribosylformylglycinamidine synthase activity
JRI60_RS32195	COG0243	molybdopterin cofactor binding
JRI60_RS32215	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JRI60_RS32340	COG1484	DNA-dependent DNA replication
JRI60_RS32345	COG4584	PFAM Integrase catalytic
JRI60_RS32360	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JRI60_RS32360	COG0392	lysyltransferase activity
JRI60_RS32370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_RS32380	COG2247	cell wall binding repeat
JRI60_RS32380	COG2385	sporulation resulting in formation of a cellular spore
JRI60_RS32390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JRI60_RS32425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JRI60_RS32425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JRI60_RS32430	COG0509	glycine decarboxylation via glycine cleavage system
JRI60_RS32440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JRI60_RS32450	COG0596	Alpha beta hydrolase
JRI60_RS32460	COG4771	TonB-dependent receptor
JRI60_RS32470	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_RS32505	COG1129	ABC transporter
JRI60_RS32520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JRI60_RS32525	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JRI60_RS32530	COG0626	cystathionine gamma-synthase activity
JRI60_RS32535	COG0626	cystathionine gamma-synthase activity
JRI60_RS32540	COG0460	homoserine dehydrogenase
JRI60_RS32540	COG0527	aspartate kinase activity
JRI60_RS32555	COG2840	Smr protein MutS2
JRI60_RS32565	COG0167	dihydroorotate dehydrogenase activity
JRI60_RS32575	COG0297	glycogen (starch) synthase activity
JRI60_RS32590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JRI60_RS32605	COG0237	dephospho-CoA kinase activity
JRI60_RS32630	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JRI60_RS32635	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JRI60_RS32695	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JRI60_RS32720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JRI60_RS32740	COG1496	oxidoreductase activity
JRI60_RS32765	COG1543	Belongs to the glycosyl hydrolase 57 family
JRI60_RS32780	COG1196	nuclear chromosome segregation
JRI60_RS32780	COG0745	RESPONSE REGULATOR receiver
JRI60_RS32790	COG0542	response to heat
JRI60_RS32795	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JRI60_RS32810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JRI60_RS32835	COG0515	serine threonine protein kinase
JRI60_RS32855	COG1692	metallophosphoesterase
JRI60_RS32860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JRI60_RS32865	COG5002	protein histidine kinase activity
JRI60_RS32870	COG1940	carbohydrate kinase activity
JRI60_RS32875	COG1129	ABC transporter
JRI60_RS32880	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRI60_RS32885	COG1879	ABC-type sugar transport system periplasmic component
JRI60_RS32895	COG0673	inositol 2-dehydrogenase activity
JRI60_RS32915	COG1408	metallophosphoesterase
JRI60_RS32920	COG0427	acetyl-CoA hydrolase
JRI60_RS32925	COG2373	Large extracellular alpha-helical protein
JRI60_RS32930	COG2135	peptidase activity
JRI60_RS32940	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JRI60_RS32955	COG0515	serine threonine protein kinase
JRI60_RS32955	COG2815	serine threonine protein kinase
JRI60_RS32960	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS32985	COG5002	protein histidine kinase activity
JRI60_RS32995	COG3321	synthase
JRI60_RS32995	COG0604	alcohol dehydrogenase
JRI60_RS33005	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS33005	COG0604	alcohol dehydrogenase
JRI60_RS33005	COG3321	synthase
JRI60_RS33010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JRI60_RS33020	COG0745	RESPONSE REGULATOR receiver
JRI60_RS33030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JRI60_RS33050	COG0277	FAD linked oxidase domain protein
JRI60_RS33055	COG0302	gtp cyclohydrolase
JRI60_RS33085	COG1121	(ABC) transporter
JRI60_RS33090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JRI60_RS33095	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_RS33100	COG0745	RESPONSE REGULATOR receiver
JRI60_RS33105	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS33110	COG1335	isochorismatase
JRI60_RS33155	COG0670	Belongs to the BI1 family
JRI60_RS33165	COG3411	Ferredoxin
JRI60_RS33170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JRI60_RS33190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JRI60_RS33195	COG0297	glycogen (starch) synthase activity
JRI60_RS33200	COG0438	transferase activity, transferring glycosyl groups
JRI60_RS33220	COG0322	excinuclease ABC activity
JRI60_RS33230	COG0515	serine threonine protein kinase
JRI60_RS33240	COG1396	sequence-specific DNA binding
JRI60_RS33255	COG0795	lipopolysaccharide-transporting ATPase activity
JRI60_RS33260	COG0151	Belongs to the GarS family
JRI60_RS33270	COG0138	bifunctional purine biosynthesis protein purh
JRI60_RS33275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JRI60_RS33290	COG0515	serine threonine protein kinase
JRI60_RS33320	COG1183	phosphatidylcholine synthase activity
JRI60_RS33335	COG0351	phosphomethylpyrimidine kinase
JRI60_RS33340	COG0534	Mate efflux family protein
JRI60_RS33345	COG4191	Histidine kinase
JRI60_RS33360	COG0515	serine threonine protein kinase
JRI60_RS33360	COG0457	Tetratricopeptide repeat
JRI60_RS33370	COG2304	oxidoreductase activity
JRI60_RS33385	COG2890	protein-(glutamine-N5) methyltransferase activity
JRI60_RS33395	COG1793	dna ligase
JRI60_RS33425	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JRI60_RS33435	COG3507	Belongs to the glycosyl hydrolase 43 family
JRI60_RS33440	COG1879	ABC-type sugar transport system periplasmic component
JRI60_RS33445	COG1129	ABC transporter
JRI60_RS33450	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRI60_RS33455	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRI60_RS33480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JRI60_RS33530	COG2433	Pfam Transposase IS66
JRI60_RS33575	COG0515	serine threonine protein kinase
JRI60_RS33620	COG4974	Belongs to the 'phage' integrase family
JRI60_RS33635	COG0149	triose-phosphate isomerase activity
JRI60_RS33640	COG0126	phosphoglycerate kinase activity
JRI60_RS33655	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JRI60_RS33665	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JRI60_RS33675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JRI60_RS33695	COG0084	hydrolase, TatD family'
JRI60_RS33705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JRI60_RS33705	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JRI60_RS33720	COG1278	Cold shock
JRI60_RS33725	COG0626	cystathionine gamma-synthase activity
JRI60_RS33730	COG1522	sequence-specific DNA binding
JRI60_RS33755	COG3850	Histidine kinase
JRI60_RS33755	COG3437	response regulator, receiver
JRI60_RS33755	COG4999	Histidine kinase
JRI60_RS33755	COG2205	protein histidine kinase activity
JRI60_RS33760	COG0521	Mo-molybdopterin cofactor biosynthetic process
JRI60_RS33770	COG1796	DNA polymerase
JRI60_RS33770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JRI60_RS33790	COG0443	Heat shock 70 kDa protein
JRI60_RS33795	COG0484	heat shock protein binding
JRI60_RS33810	COG1166	arginine decarboxylase activity
JRI60_RS33815	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JRI60_RS33815	COG2755	lipolytic protein G-D-S-L family
JRI60_RS33840	COG1752	Esterase of the alpha-beta hydrolase superfamily
JRI60_RS33860	COG1899	peptidyl-lysine modification to peptidyl-hypusine
JRI60_RS33870	COG1959	2 iron, 2 sulfur cluster binding
JRI60_RS33875	COG0613	PHP domain protein
JRI60_RS33880	COG2124	cytochrome p450
JRI60_RS33890	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JRI60_RS33895	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JRI60_RS33905	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JRI60_RS33910	COG0649	NAD binding
JRI60_RS33915	COG1034	ATP synthesis coupled electron transport
JRI60_RS33920	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JRI60_RS33925	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JRI60_RS33985	COG0739	heme binding
JRI60_RS33990	COG3246	L-lysine catabolic process to acetate
JRI60_RS33995	COG1024	Enoyl-CoA hydratase
JRI60_RS34000	COG1309	transcriptional regulator
JRI60_RS34010	COG1396	sequence-specific DNA binding
JRI60_RS34045	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JRI60_RS34055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS34060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JRI60_RS34065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JRI60_RS34070	COG1683	Conserved Protein
JRI60_RS34075	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JRI60_RS34085	COG1309	transcriptional regulator
JRI60_RS34095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JRI60_RS34100	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JRI60_RS34120	COG1473	amidohydrolase
JRI60_RS34130	COG1846	Transcriptional regulator
JRI60_RS34140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JRI60_RS34145	COG1100	Small GTP-binding protein
JRI60_RS34170	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JRI60_RS34200	COG0625	glutathione transferase activity
JRI60_RS34225	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
JRI60_RS34260	COG0626	cystathionine gamma-synthase activity
JRI60_RS34265	COG2076	Multidrug Resistance protein
JRI60_RS34325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JRI60_RS34345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JRI60_RS34380	COG1760	l-serine dehydratase
JRI60_RS34430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JRI60_RS34430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JRI60_RS34430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JRI60_RS34435	COG1105	Belongs to the carbohydrate kinase PfkB family
JRI60_RS34440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JRI60_RS34440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRI60_RS34445	COG1609	Transcriptional regulator
JRI60_RS34455	COG3590	peptidase
JRI60_RS34510	COG3795	YCII-related domain
JRI60_RS34515	COG0564	pseudouridine synthase activity
JRI60_RS34525	COG2308	Evidence 4 Homologs of previously reported genes of
JRI60_RS34535	COG0121	glutamine amidotransferase
JRI60_RS34560	COG0596	Alpha beta hydrolase
JRI60_RS34590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS34615	COG4221	oxidoreductase activity
JRI60_RS34635	COG0586	Pfam SNARE associated Golgi protein
JRI60_RS34650	COG0784	Response regulator, receiver
JRI60_RS34655	COG0840	transmembrane signaling receptor activity
JRI60_RS34695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JRI60_RS34730	COG3852	Histidine kinase
JRI60_RS34745	COG0508	dehydrogenase complex catalyzes the overall conversion of
JRI60_RS34750	COG0508	dehydrogenase complex catalyzes the overall conversion of
JRI60_RS34750	COG0022	dehydrogenase e1 component
JRI60_RS34755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JRI60_RS34780	COG0737	Belongs to the 5'-nucleotidase family
JRI60_RS34805	COG0312	modulator of DNA gyrase
JRI60_RS34815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRI60_RS34830	COG0181	hydroxymethylbilane synthase activity
JRI60_RS34835	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JRI60_RS34840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JRI60_RS34850	COG3118	belongs to the thioredoxin family
JRI60_RS34860	COG2239	Acts as a magnesium transporter
JRI60_RS34870	COG0772	Belongs to the SEDS family
JRI60_RS34875	COG0768	penicillin binding
JRI60_RS34890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRI60_RS34895	COG5001	Diguanylate cyclase
JRI60_RS34900	COG0424	maF-like protein
JRI60_RS34945	COG0322	excinuclease ABC activity
JRI60_RS34950	COG0556	nucleotide-excision repair
JRI60_RS34960	COG0215	cysteine-tRNA ligase activity
JRI60_RS34965	COG1716	ATPase activity
JRI60_RS34975	COG1329	Transcriptional regulator
JRI60_RS34980	COG2333	competence protein COMEC
JRI60_RS34980	COG0658	competence protein
JRI60_RS35005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JRI60_RS35010	COG1074	ATP-dependent DNA helicase activity
JRI60_RS35040	COG0604	alcohol dehydrogenase
JRI60_RS35055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRI60_RS35060	COG4558	Periplasmic binding protein
JRI60_RS35070	COG2207	Transcriptional regulator
JRI60_RS35100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JRI60_RS35120	COG2130	NADP-dependent
JRI60_RS35135	COG4584	PFAM Integrase catalytic
JRI60_RS35140	COG1484	DNA-dependent DNA replication
JRI60_RS35165	COG1819	glycosyl
JRI60_RS35230	COG0515	serine threonine protein kinase
JRI60_RS35245	COG2815	serine threonine protein kinase
JRI60_RS35245	COG0515	serine threonine protein kinase
JRI60_RS35260	COG5006	permease, DMT superfamily
JRI60_RS35275	COG3940	Belongs to the glycosyl hydrolase 43 family
JRI60_RS35315	COG4968	Prepilin-type N-terminal cleavage methylation domain
JRI60_RS35335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JRI60_RS35335	COG2124	cytochrome p450
JRI60_RS35355	COG0183	Belongs to the thiolase family
JRI60_RS35360	COG0477	Major facilitator Superfamily
JRI60_RS35385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS35390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS35400	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_RS35435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JRI60_RS35440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_RS35445	COG0784	Response regulator, receiver
JRI60_RS35445	COG2205	protein histidine kinase activity
JRI60_RS35460	COG0693	protein deglycase activity
JRI60_RS35460	COG0753	catalase activity
JRI60_RS35465	COG1657	PFAM Prenyltransferase squalene oxidase
JRI60_RS35470	COG2203	Gaf domain
JRI60_RS35470	COG0840	transmembrane signaling receptor activity
JRI60_RS35515	COG2204	response regulator
JRI60_RS35535	COG0659	secondary active sulfate transmembrane transporter activity
JRI60_RS35540	COG2205	protein histidine kinase activity
JRI60_RS35545	COG2204	response regulator
JRI60_RS35565	COG2205	protein histidine kinase activity
JRI60_RS35570	COG0745	RESPONSE REGULATOR receiver
JRI60_RS35600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JRI60_RS35635	COG2815	serine threonine protein kinase
JRI60_RS35635	COG0515	serine threonine protein kinase
JRI60_RS35655	COG5297	Belongs to the glycosyl hydrolase family 6
JRI60_RS35660	COG1349	DNA-binding transcription factor activity
JRI60_RS35665	COG0494	nUDIX hydrolase
JRI60_RS35675	COG0477	Major facilitator Superfamily
JRI60_RS35715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JRI60_RS35770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRI60_RS35775	COG1278	Cold shock
JRI60_RS35780	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS35785	COG0495	leucyl-tRNA aminoacylation
JRI60_RS35825	COG2197	response regulator
JRI60_RS35915	COG3275	phosphorelay sensor kinase activity
JRI60_RS35920	COG3279	Response regulator of the LytR AlgR family
JRI60_RS35990	COG0848	biopolymer transport protein
JRI60_RS36000	COG0739	heme binding
JRI60_RS36000	COG1196	nuclear chromosome segregation
JRI60_RS36000	COG0741	lytic transglycosylase activity
JRI60_RS36035	COG0784	Response regulator, receiver
JRI60_RS36035	COG2205	protein histidine kinase activity
JRI60_RS36045	COG0596	Alpha beta hydrolase
JRI60_RS36065	COG0667	Aldo Keto reductase
JRI60_RS36130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRI60_RS36145	COG1690	Belongs to the RtcB family
JRI60_RS36150	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JRI60_RS36155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JRI60_RS36165	COG0254	rRNA binding
JRI60_RS36180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JRI60_RS36185	COG2201	protein-glutamate methylesterase activity
JRI60_RS36215	COG2885	chlorophyll binding
JRI60_RS36225	COG2205	protein histidine kinase activity
JRI60_RS36245	COG2204	response regulator
JRI60_RS36250	COG2259	Doxx family
JRI60_RS36255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JRI60_RS36260	COG0517	IMP dehydrogenase activity
JRI60_RS36260	COG0516	GMP reductase activity
JRI60_RS36300	COG0708	Exodeoxyribonuclease III
JRI60_RS36325	COG5000	phosphorelay sensor kinase activity
JRI60_RS36350	COG4584	PFAM Integrase catalytic
JRI60_RS36355	COG1484	DNA-dependent DNA replication
JRI60_RS36395	COG0513	Belongs to the DEAD box helicase family
JRI60_RS36425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JRI60_RS36435	COG2084	Dehydrogenase
JRI60_RS36475	COG2885	chlorophyll binding
JRI60_RS36475	COG3047	cAMP biosynthetic process
JRI60_RS36485	COG0585	pseudouridine synthase activity
JRI60_RS36495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_RS36495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRI60_RS36500	COG0252	asparaginase activity
JRI60_RS36590	COG1278	Cold shock
JRI60_RS36605	COG0745	RESPONSE REGULATOR receiver
JRI60_RS36610	COG2205	protein histidine kinase activity
JRI60_RS36625	COG1131	(ABC) transporter
JRI60_RS36630	COG0109	protoheme IX farnesyltransferase activity
JRI60_RS36655	COG0443	Heat shock 70 kDa protein
JRI60_RS36660	COG1126	abc transporter atp-binding protein
JRI60_RS36665	COG0765	amino acid transport
JRI60_RS36670	COG2208	phosphoserine phosphatase activity
JRI60_RS36675	COG0596	Alpha beta hydrolase
JRI60_RS36700	COG1752	Esterase of the alpha-beta hydrolase superfamily
JRI60_RS36710	COG1022	Amp-dependent synthetase and ligase
JRI60_RS36715	COG0596	Alpha beta hydrolase
JRI60_RS36725	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS36750	COG0475	glutathione-regulated potassium exporter activity
JRI60_RS36780	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS36800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JRI60_RS36815	COG0543	2 iron, 2 sulfur cluster binding
JRI60_RS36815	COG0493	'glutamate synthase
JRI60_RS36825	COG2062	phosphohistidine phosphatase, SixA
JRI60_RS36830	COG1965	Belongs to the frataxin family
JRI60_RS36840	COG0233	cytoplasmic translational termination
JRI60_RS36845	COG0528	UMP kinase activity
JRI60_RS36850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JRI60_RS36855	COG0052	Belongs to the universal ribosomal protein uS2 family
JRI60_RS36860	COG0653	protein targeting
JRI60_RS36865	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JRI60_RS36875	COG0739	heme binding
JRI60_RS36880	COG0631	protein serine/threonine phosphatase activity
JRI60_RS36885	COG0497	DNA recombination
JRI60_RS36890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_RS36895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JRI60_RS36900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JRI60_RS36910	COG1309	transcriptional regulator
JRI60_RS36915	COG2223	nitrite transmembrane transporter activity
JRI60_RS36920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JRI60_RS36930	COG0737	Belongs to the 5'-nucleotidase family
JRI60_RS36940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JRI60_RS36945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JRI60_RS36955	COG5002	protein histidine kinase activity
JRI60_RS36960	COG3706	GGDEF domain
JRI60_RS36965	COG0463	Glycosyl transferase, family 2
JRI60_RS36970	COG3394	polysaccharide catabolic process
JRI60_RS36990	COG1024	Enoyl-CoA hydratase
JRI60_RS36990	COG1250	3-hydroxyacyl-CoA dehydrogenase
JRI60_RS36995	COG0183	Belongs to the thiolase family
JRI60_RS37010	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JRI60_RS37050	COG4221	oxidoreductase activity
JRI60_RS37070	COG0456	acetyltransferase
JRI60_RS37080	COG0515	serine threonine protein kinase
JRI60_RS37080	COG2815	serine threonine protein kinase
JRI60_RS37120	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JRI60_RS37125	COG0515	serine threonine protein kinase
JRI60_RS37135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JRI60_RS37155	COG2815	serine threonine protein kinase
JRI60_RS37155	COG0515	serine threonine protein kinase
JRI60_RS37160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRI60_RS37170	COG3852	Histidine kinase
JRI60_RS37175	COG2204	response regulator
JRI60_RS37245	COG0438	transferase activity, transferring glycosyl groups
JRI60_RS37255	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JRI60_RS37275	COG0583	DNA-binding transcription factor activity
JRI60_RS37290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_RS37305	COG0531	amino acid
JRI60_RS37375	COG2304	oxidoreductase activity
JRI60_RS37395	COG0546	phosphoglycolate phosphatase activity
JRI60_RS37400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_RS37405	COG0596	Alpha beta hydrolase
JRI60_RS37415	COG4702	Belongs to the UPF0303 family
JRI60_RS37420	COG0300	oxidoreductase activity
JRI60_RS37440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JRI60_RS37450	COG2010	Cytochrome c
JRI60_RS37460	COG3278	Belongs to the heme-copper respiratory oxidase family
JRI60_RS37495	COG1404	Belongs to the peptidase S8 family
JRI60_RS37505	COG0515	serine threonine protein kinase
JRI60_RS37510	COG4268	DNA restriction-modification system
JRI60_RS37515	COG1401	restriction endodeoxyribonuclease activity
JRI60_RS37540	COG0437	4 iron, 4 sulfur cluster binding
JRI60_RS37575	COG1858	cytochrome C peroxidase
JRI60_RS37600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRI60_RS37620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_RS37630	COG2234	aminopeptidase activity
JRI60_RS37650	COG0006	proline dipeptidase activity
JRI60_RS37660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JRI60_RS37675	COG1621	beta-fructofuranosidase activity
JRI60_RS37710	COG1819	glycosyl
JRI60_RS37720	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JRI60_RS37725	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JRI60_RS37730	COG0271	Belongs to the BolA IbaG family
JRI60_RS37735	COG1678	Uncharacterized ACR, COG1678
JRI60_RS37740	COG4565	transcriptional regulatory protein
JRI60_RS37755	COG4166	transmembrane transport
JRI60_RS37765	COG1505	serine-type exopeptidase activity
JRI60_RS37775	COG0740	serine-type endopeptidase activity
JRI60_RS37780	COG0544	peptidyl-prolyl cis-trans isomerase activity
JRI60_RS37820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JRI60_RS37825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JRI60_RS37830	COG0860	N-Acetylmuramoyl-L-alanine amidase
JRI60_RS37850	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JRI60_RS37855	COG2137	regulation of response to DNA damage stimulus
JRI60_RS37875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JRI60_RS37880	COG0210	DNA helicase
JRI60_RS37895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JRI60_RS37950	COG0084	hydrolase, TatD family'
JRI60_RS37955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JRI60_RS37975	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS38030	COG1410	methionine synthase
JRI60_RS38030	COG0646	methionine synthase
JRI60_RS38035	COG2226	methyltransferase
JRI60_RS38050	COG1832	CoA-binding protein
JRI60_RS38065	COG0515	serine threonine protein kinase
JRI60_RS38140	COG1063	alcohol dehydrogenase
JRI60_RS38145	COG1181	Belongs to the D-alanine--D-alanine ligase family
JRI60_RS38155	COG3425	synthase
JRI60_RS38175	COG1309	transcriptional regulator
JRI60_RS38185	COG0315	cyclic pyranopterin monophosphate synthase activity
JRI60_RS38195	COG0492	ferredoxin-NADP+ reductase activity
JRI60_RS38200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS38205	COG5002	protein histidine kinase activity
JRI60_RS38210	COG0745	RESPONSE REGULATOR receiver
JRI60_RS38375	COG1335	isochorismatase
JRI60_RS38415	COG2022	thiamine diphosphate biosynthetic process
JRI60_RS38440	COG2124	cytochrome p450
JRI60_RS38455	COG1673	EVE domain
JRI60_RS38470	COG2202	Pas domain
JRI60_RS38470	COG2205	protein histidine kinase activity
JRI60_RS38490	COG0667	Aldo Keto reductase
JRI60_RS38495	COG2003	Belongs to the UPF0758 family
JRI60_RS38505	COG0514	ATP-dependent DNA helicase (RecQ)
JRI60_RS38535	COG0204	Acyl-transferase
JRI60_RS38550	COG0515	serine threonine protein kinase
JRI60_RS38550	COG2815	serine threonine protein kinase
JRI60_RS38575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JRI60_RS38595	COG0590	tRNA wobble adenosine to inosine editing
JRI60_RS38620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JRI60_RS38630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JRI60_RS38635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JRI60_RS38640	COG0515	serine threonine protein kinase
JRI60_RS38660	COG1100	Small GTP-binding protein
JRI60_RS38720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_RS38725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JRI60_RS38730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JRI60_RS38735	COG1619	proteins homologs of microcin C7 resistance protein MccF
JRI60_RS38740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JRI60_RS38740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JRI60_RS38760	COG1404	Belongs to the peptidase S8 family
JRI60_RS38765	COG0464	growth
JRI60_RS38815	COG3781	membrane
JRI60_RS38825	COG0534	Mate efflux family protein
JRI60_RS38900	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS38900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_RS38900	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS38900	COG3321	synthase
JRI60_RS38900	COG0300	oxidoreductase activity
JRI60_RS38935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JRI60_RS38950	COG0656	L-ascorbic acid biosynthetic process
JRI60_RS38955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JRI60_RS38965	COG0512	Glutamine amidotransferase of anthranilate synthase
JRI60_RS38975	COG2205	protein histidine kinase activity
JRI60_RS38980	COG1187	pseudouridine synthase activity
JRI60_RS39000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_RS39025	COG0515	serine threonine protein kinase
JRI60_RS39055	COG2311	Membrane
JRI60_RS39060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRI60_RS39060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_RS39070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JRI60_RS39095	COG3135	benzoate transporter
JRI60_RS39140	COG2205	protein histidine kinase activity
JRI60_RS39155	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS39160	COG2814	Major facilitator Superfamily
JRI60_RS39185	COG3854	ATPases associated with a variety of cellular activities
JRI60_RS39205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JRI60_RS39210	COG1196	nuclear chromosome segregation
JRI60_RS39220	COG0741	lytic transglycosylase activity
JRI60_RS39220	COG1196	nuclear chromosome segregation
JRI60_RS39220	COG0739	heme binding
JRI60_RS39240	COG0450	alkyl hydroperoxide reductase
JRI60_RS39245	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JRI60_RS39250	COG0783	Belongs to the Dps family
JRI60_RS39260	COG1505	serine-type exopeptidase activity
JRI60_RS39265	COG3590	peptidase
JRI60_RS39290	COG1309	transcriptional regulator
JRI60_RS39295	COG3243	poly(R)-hydroxyalkanoic acid synthase
JRI60_RS39315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JRI60_RS39325	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JRI60_RS39345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_RS39350	COG2010	Cytochrome c
JRI60_RS39355	COG3359	exonuclease
JRI60_RS39360	COG1111	helicase
JRI60_RS39360	COG1205	dead DEAH box helicase
JRI60_RS39365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JRI60_RS39390	COG0723	plastoquinol--plastocyanin reductase activity
JRI60_RS39390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JRI60_RS39425	COG1131	(ABC) transporter
JRI60_RS39435	COG0009	L-threonylcarbamoyladenylate synthase
JRI60_RS39445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JRI60_RS39450	COG2967	ApaG domain
JRI60_RS39475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_RS39495	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS39500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_RS39510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JRI60_RS39525	COG5002	protein histidine kinase activity
JRI60_RS39530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JRI60_RS39575	COG0702	epimerase
JRI60_RS39595	COG2205	protein histidine kinase activity
JRI60_RS39595	COG0784	Response regulator, receiver
JRI60_RS39600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JRI60_RS39620	COG5002	protein histidine kinase activity
JRI60_RS39630	COG4251	negative regulation of phosphorylation
JRI60_RS39715	COG0189	ligase activity
JRI60_RS39725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_RS39830	COG2234	aminopeptidase activity
JRI60_RS39875	COG5183	chlorophyll binding
JRI60_RS39875	COG2133	pyrroloquinoline quinone binding
JRI60_RS39895	COG2267	carboxylic ester hydrolase activity
JRI60_RS39910	COG1072	(Pantothenic acid kinase))
JRI60_RS39975	COG0714	Associated with various cellular activities
JRI60_RS39985	COG3552	Protein containing von Willebrand factor type A (VWA) domain
JRI60_RS39990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JRI60_RS40010	COG5002	protein histidine kinase activity
JRI60_RS40040	COG0784	Response regulator, receiver
JRI60_RS40055	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JRI60_RS40060	COG1666	GTP binding
JRI60_RS40070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JRI60_RS40110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JRI60_RS40115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JRI60_RS40120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JRI60_RS40140	COG4191	Histidine kinase
JRI60_RS40150	COG2205	protein histidine kinase activity
JRI60_RS40180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JRI60_RS40185	COG0583	DNA-binding transcription factor activity
JRI60_RS40190	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS40205	COG3279	Response regulator of the LytR AlgR family
JRI60_RS40210	COG3275	phosphorelay sensor kinase activity
JRI60_RS40215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JRI60_RS40220	COG0154	amidase activity
JRI60_RS40225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JRI60_RS40260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JRI60_RS40260	COG0116	Belongs to the methyltransferase superfamily
JRI60_RS40265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JRI60_RS40340	COG1252	NADH dehydrogenase
JRI60_RS40345	COG0204	Acyl-transferase
JRI60_RS40365	COG1058	Belongs to the CinA family
JRI60_RS40365	COG1546	Belongs to the CinA family
JRI60_RS40370	COG1183	phosphatidylcholine synthase activity
JRI60_RS40385	COG0776	regulation of translation
JRI60_RS40390	COG0739	heme binding
JRI60_RS40400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JRI60_RS40405	COG0242	peptide deformylase activity
JRI60_RS40415	COG0484	heat shock protein binding
JRI60_RS40420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JRI60_RS40465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JRI60_RS40490	COG1215	transferase activity, transferring glycosyl groups
JRI60_RS40560	COG5002	protein histidine kinase activity
JRI60_RS40565	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_RS40575	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS40585	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS40605	COG0596	Alpha beta hydrolase
JRI60_RS40630	COG2205	protein histidine kinase activity
JRI60_RS40635	COG0515	serine threonine protein kinase
JRI60_RS40645	COG1454	alcohol dehydrogenase
JRI60_RS40650	COG0824	Thioesterase
JRI60_RS40690	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS40725	COG0515	serine threonine protein kinase
JRI60_RS40730	COG5002	protein histidine kinase activity
JRI60_RS40735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JRI60_RS40740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JRI60_RS40745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JRI60_RS40805	COG1366	Belongs to the anti-sigma-factor antagonist family
JRI60_RS40815	COG1366	Belongs to the anti-sigma-factor antagonist family
JRI60_RS40845	COG0667	Aldo Keto reductase
JRI60_RS40850	COG2204	response regulator
JRI60_RS40860	COG2183	response to ionizing radiation
JRI60_RS40880	COG1304	FMN binding
JRI60_RS40885	COG1115	amino acid carrier protein
JRI60_RS40890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_RS40905	COG4948	Mandelate Racemase Muconate Lactonizing
JRI60_RS40935	COG1132	(ABC) transporter
JRI60_RS40950	COG0515	serine threonine protein kinase
JRI60_RS40960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JRI60_RS40970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JRI60_RS40975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JRI60_RS40985	COG0405	Gamma-glutamyltransferase
JRI60_RS41015	COG0788	formyltetrahydrofolate deformylase activity
JRI60_RS41080	COG0513	Belongs to the DEAD box helicase family
JRI60_RS41090	COG1741	Belongs to the pirin family
JRI60_RS41110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JRI60_RS41115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JRI60_RS41125	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JRI60_RS41150	COG0515	serine threonine protein kinase
JRI60_RS41155	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS41155	COG1672	PFAM Archaeal ATPase
JRI60_RS41165	COG5002	protein histidine kinase activity
JRI60_RS41165	COG3850	Histidine kinase
JRI60_RS41170	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS41180	COG2070	2-Nitropropane dioxygenase
JRI60_RS41190	COG0583	DNA-binding transcription factor activity
JRI60_RS41205	COG2815	serine threonine protein kinase
JRI60_RS41205	COG0515	serine threonine protein kinase
JRI60_RS41215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JRI60_RS41230	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS41235	COG0583	DNA-binding transcription factor activity
JRI60_RS41265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JRI60_RS41270	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS41295	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
JRI60_RS41305	COG1716	ATPase activity
JRI60_RS41325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JRI60_RS41340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JRI60_RS41350	COG5002	protein histidine kinase activity
JRI60_RS41355	COG0745	RESPONSE REGULATOR receiver
JRI60_RS41380	COG1228	amidohydrolase
JRI60_RS41405	COG1073	alpha beta
JRI60_RS41460	COG0402	S-adenosylhomocysteine deaminase activity
JRI60_RS41490	COG1007	ATP synthesis coupled electron transport
JRI60_RS41625	COG0730	response to heat
JRI60_RS41635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JRI60_RS41650	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS41655	COG0596	Alpha beta hydrolase
JRI60_RS41660	COG1024	Enoyl-CoA hydratase
JRI60_RS41700	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JRI60_RS41705	COG3852	Histidine kinase
JRI60_RS41710	COG3852	Histidine kinase
JRI60_RS41745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JRI60_RS41745	COG4651	solute:proton antiporter activity
JRI60_RS41770	COG0515	serine threonine protein kinase
JRI60_RS41775	COG0297	glycogen (starch) synthase activity
JRI60_RS41795	COG3275	phosphorelay sensor kinase activity
JRI60_RS41800	COG4585	Histidine kinase
JRI60_RS41805	COG0745	RESPONSE REGULATOR receiver
JRI60_RS41810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JRI60_RS41810	COG0784	Response regulator, receiver
JRI60_RS41820	COG1484	DNA-dependent DNA replication
JRI60_RS41825	COG4584	PFAM Integrase catalytic
JRI60_RS41840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JRI60_RS41865	COG2124	cytochrome p450
JRI60_RS41870	COG2124	cytochrome p450
JRI60_RS41890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JRI60_RS41935	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS41940	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JRI60_RS41955	COG4221	oxidoreductase activity
JRI60_RS41960	COG2207	Transcriptional regulator
JRI60_RS41985	COG0346	lactoylglutathione lyase activity
JRI60_RS41990	COG1940	carbohydrate kinase activity
JRI60_RS42005	COG1793	dna ligase
JRI60_RS42010	COG1201	RNA secondary structure unwinding
JRI60_RS42020	COG2124	cytochrome p450
JRI60_RS42025	COG3279	Response regulator of the LytR AlgR family
JRI60_RS42050	COG0644	oxidoreductase
JRI60_RS42065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JRI60_RS42075	COG0644	oxidoreductase
JRI60_RS42090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JRI60_RS42110	COG5002	protein histidine kinase activity
JRI60_RS42115	COG0471	metal ion transport
JRI60_RS42115	COG3273	potassium ion transport
JRI60_RS42120	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JRI60_RS42155	COG4221	oxidoreductase activity
JRI60_RS42155	COG3321	synthase
JRI60_RS42155	COG0300	oxidoreductase activity
JRI60_RS42155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_RS42170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_RS42175	COG1297	OPT oligopeptide transporter protein
JRI60_RS42180	COG4251	negative regulation of phosphorylation
JRI60_RS42185	COG0784	Response regulator, receiver
JRI60_RS42200	COG0436	Aminotransferase
JRI60_RS42210	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JRI60_RS42215	COG0156	8-amino-7-oxononanoate synthase activity
JRI60_RS42220	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JRI60_RS42230	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JRI60_RS42285	COG5297	Belongs to the glycosyl hydrolase family 6
JRI60_RS42290	COG1876	peptidase activity
JRI60_RS42310	COG5464	transposase or invertase
JRI60_RS42315	COG3852	Histidine kinase
JRI60_RS42320	COG4251	negative regulation of phosphorylation
JRI60_RS42330	COG2205	protein histidine kinase activity
JRI60_RS42380	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JRI60_RS42385	COG0471	metal ion transport
JRI60_RS42385	COG3273	potassium ion transport
JRI60_RS42390	COG0561	phosphatase activity
JRI60_RS42395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JRI60_RS42400	COG1690	Belongs to the RtcB family
JRI60_RS42415	COG0205	6-phosphofructokinase activity
JRI60_RS42425	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JRI60_RS42435	COG4191	Histidine kinase
JRI60_RS42465	COG5002	protein histidine kinase activity
JRI60_RS42475	COG2205	protein histidine kinase activity
JRI60_RS42505	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_RS42525	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JRI60_RS42555	COG0432	Pfam Uncharacterised protein family UPF0047
JRI60_RS42560	COG2204	response regulator
JRI60_RS42565	COG4251	negative regulation of phosphorylation
JRI60_RS42580	COG5001	Diguanylate cyclase
JRI60_RS42590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRI60_RS42645	COG1024	Enoyl-CoA hydratase
JRI60_RS42655	COG2151	metal-sulfur cluster biosynthetic enzyme
JRI60_RS42660	COG0822	iron-sulfur transferase activity
JRI60_RS42670	COG0719	Fe-S assembly protein
JRI60_RS42675	COG0396	ATPase activity
JRI60_RS42680	COG0719	Fe-S assembly protein
JRI60_RS42685	COG1959	2 iron, 2 sulfur cluster binding
JRI60_RS42755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JRI60_RS42765	COG0612	Peptidase, M16
JRI60_RS42795	COG2264	protein methyltransferase activity
JRI60_RS42820	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JRI60_RS42830	COG1714	RDD family
JRI60_RS42840	COG4191	Histidine kinase
JRI60_RS42890	COG2204	response regulator
JRI60_RS42895	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS42925	COG2264	protein methyltransferase activity
JRI60_RS42935	COG2264	protein methyltransferase activity
JRI60_RS42970	COG0339	signal peptide processing
JRI60_RS43005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JRI60_RS43015	COG0439	Biotin carboxylase
JRI60_RS43020	COG0511	ligase activity, forming carbon-carbon bonds
JRI60_RS43020	COG5016	pyruvate
JRI60_RS43025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JRI60_RS43025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JRI60_RS43055	COG0484	heat shock protein binding
JRI60_RS43070	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JRI60_RS43075	COG0519	Catalyzes the synthesis of GMP from XMP
JRI60_RS43095	COG0564	pseudouridine synthase activity
JRI60_RS43110	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JRI60_RS43115	COG1132	(ABC) transporter
JRI60_RS43125	COG0504	CTP synthase activity
JRI60_RS43130	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JRI60_RS43135	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JRI60_RS43145	COG0071	Belongs to the small heat shock protein (HSP20) family
JRI60_RS43170	COG2815	serine threonine protein kinase
JRI60_RS43170	COG0515	serine threonine protein kinase
JRI60_RS43190	COG0839	Belongs to the complex I subunit 6 family
JRI60_RS43195	COG0713	ATP synthesis coupled electron transport
JRI60_RS43200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JRI60_RS43210	COG1007	ATP synthesis coupled electron transport
JRI60_RS43215	COG2204	response regulator
JRI60_RS43220	COG4191	Histidine kinase
JRI60_RS43230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JRI60_RS43235	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JRI60_RS43245	COG0629	single-stranded DNA binding
JRI60_RS43250	COG2027	D-alanyl-D-alanine carboxypeptidase
JRI60_RS43260	COG0747	negative chemotaxis
JRI60_RS43265	COG0601	transmembrane transport
JRI60_RS43270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JRI60_RS43275	COG2153	protein acetylation
JRI60_RS43325	COG1309	transcriptional regulator
JRI60_RS43355	COG1490	D-aminoacyl-tRNA deacylase activity
JRI60_RS43365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRI60_RS43370	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_RS43405	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JRI60_RS43410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JRI60_RS43435	COG2267	carboxylic ester hydrolase activity
JRI60_RS43465	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS43520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_RS43560	COG0745	RESPONSE REGULATOR receiver
JRI60_RS43575	COG1733	regulation of RNA biosynthetic process
JRI60_RS43650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JRI60_RS43655	COG3848	Pyruvate phosphate dikinase
JRI60_RS43655	COG0574	Belongs to the PEP-utilizing enzyme family
JRI60_RS43685	COG2133	pyrroloquinoline quinone binding
JRI60_RS43730	COG2259	Doxx family
JRI60_RS43735	COG0583	DNA-binding transcription factor activity
JRI60_RS43790	COG0784	Response regulator, receiver
JRI60_RS43790	COG2205	protein histidine kinase activity
JRI60_RS43835	COG2124	cytochrome p450
JRI60_RS43840	COG1309	transcriptional regulator
JRI60_RS43850	COG1408	metallophosphoesterase
JRI60_RS43885	COG0657	acetylesterase activity
JRI60_RS43895	COG0583	DNA-binding transcription factor activity
JRI60_RS43935	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS43970	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS43980	COG0438	transferase activity, transferring glycosyl groups
JRI60_RS43995	COG1137	ATPase activity
JRI60_RS44010	COG1560	Kdo2-lipid A biosynthetic process
JRI60_RS44015	COG3724	N-succinylarginine dihydrolase activity
JRI60_RS44075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JRI60_RS44085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JRI60_RS44110	COG1874	Beta-galactosidase
JRI60_RS44110	COG0366	Alpha amylase catalytic
JRI60_RS44120	COG2124	cytochrome p450
JRI60_RS44155	COG0438	transferase activity, transferring glycosyl groups
JRI60_RS44165	COG0438	transferase activity, transferring glycosyl groups
JRI60_RS44180	COG0489	protein tyrosine kinase activity
JRI60_RS44210	COG1696	Membrane protein involved in D-alanine export
JRI60_RS44260	COG1999	signal sequence binding
JRI60_RS44300	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JRI60_RS44310	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JRI60_RS44360	COG2322	membrane
JRI60_RS44365	COG5002	protein histidine kinase activity
JRI60_RS44370	COG0784	Response regulator, receiver
JRI60_RS44375	COG4251	negative regulation of phosphorylation
JRI60_RS44385	COG1404	Belongs to the peptidase S8 family
JRI60_RS44390	COG3842	ATPase activity
JRI60_RS44395	COG3842	ATPase activity
JRI60_RS44405	COG0395	ABC-type sugar transport system, permease component
JRI60_RS44450	COG1201	RNA secondary structure unwinding
JRI60_RS44480	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
JRI60_RS44500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JRI60_RS44530	COG2010	Cytochrome c
JRI60_RS44530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JRI60_RS44560	COG0420	3'-5' exonuclease activity
JRI60_RS44575	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS44630	COG4555	ABC transporter
JRI60_RS44635	COG1668	transmembrane transport
JRI60_RS44645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JRI60_RS44650	COG0363	glucosamine-6-phosphate deaminase activity
JRI60_RS44655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JRI60_RS44670	COG2010	Cytochrome c
JRI60_RS44670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JRI60_RS44695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JRI60_RS44715	COG2205	protein histidine kinase activity
JRI60_RS44720	COG4191	Histidine kinase
JRI60_RS44725	COG0217	transcriptional regulatory protein
JRI60_RS44730	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JRI60_RS44735	COG3005	denitrification pathway
JRI60_RS44745	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JRI60_RS44750	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JRI60_RS44775	COG1876	peptidase activity
JRI60_RS44810	COG0515	serine threonine protein kinase
JRI60_RS44810	COG2815	serine threonine protein kinase
JRI60_RS44825	COG3425	synthase
JRI60_RS44860	COG0028	Belongs to the TPP enzyme family
JRI60_RS44905	COG1233	COG1233 Phytoene dehydrogenase and related
JRI60_RS44915	COG1562	ergosterol biosynthetic process
JRI60_RS44925	COG0142	geranyltranstransferase activity
JRI60_RS44935	COG1090	epimerase
JRI60_RS44940	COG1408	metallophosphoesterase
JRI60_RS44945	COG1309	transcriptional regulator
JRI60_RS45045	COG0783	Belongs to the Dps family
JRI60_RS45055	COG0625	glutathione transferase activity
JRI60_RS45060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JRI60_RS45065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JRI60_RS45080	COG0443	Heat shock 70 kDa protein
JRI60_RS45095	COG0242	peptide deformylase activity
JRI60_RS45110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_RS45110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS45125	COG0596	Alpha beta hydrolase
JRI60_RS45150	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_RS45155	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_RS45170	COG1858	cytochrome C peroxidase
JRI60_RS45190	COG1522	sequence-specific DNA binding
JRI60_RS45195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRI60_RS45255	COG1876	peptidase activity
JRI60_RS45265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_RS45280	COG0436	Aminotransferase
JRI60_RS45300	COG0826	peptidase U32
JRI60_RS45310	COG0287	Prephenate dehydrogenase
JRI60_RS45310	COG1605	Chorismate mutase
JRI60_RS45325	COG2376	Dihydroxyacetone kinase
JRI60_RS45330	COG2205	protein histidine kinase activity
JRI60_RS45335	COG1994	Peptidase M50
JRI60_RS45390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JRI60_RS45420	COG5002	protein histidine kinase activity
JRI60_RS45425	COG0784	Response regulator, receiver
JRI60_RS45430	COG4251	negative regulation of phosphorylation
JRI60_RS45440	COG4772	TonB-dependent receptor
JRI60_RS45450	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_RS45455	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS45465	COG4783	chaperone-mediated protein folding
JRI60_RS45475	COG3227	Zinc metalloprotease (Elastase)
JRI60_RS45495	COG0612	Peptidase, M16
JRI60_RS45500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_RS45540	COG0583	DNA-binding transcription factor activity
JRI60_RS45545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JRI60_RS45555	COG0438	transferase activity, transferring glycosyl groups
JRI60_RS45565	COG0330	HflC and HflK could
JRI60_RS45605	COG4977	sequence-specific DNA binding
JRI60_RS45640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JRI60_RS45695	COG3107	peptidoglycan biosynthetic process
JRI60_RS45715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JRI60_RS45725	COG0515	serine threonine protein kinase
JRI60_RS45730	COG2204	response regulator
JRI60_RS45740	COG3227	Zinc metalloprotease (Elastase)
JRI60_RS45750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JRI60_RS45755	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_RS45765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRI60_RS45770	COG0484	heat shock protein binding
JRI60_RS45780	COG1132	(ABC) transporter
JRI60_RS45815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_RS45820	COG5002	protein histidine kinase activity
JRI60_RS45835	COG4999	Histidine kinase
JRI60_RS45835	COG3850	Histidine kinase
JRI60_RS45835	COG2205	protein histidine kinase activity
JRI60_RS45835	COG3437	response regulator, receiver
JRI60_RS45865	COG0515	serine threonine protein kinase
JRI60_RS45865	COG3266	domain, Protein
JRI60_RS45900	COG5002	protein histidine kinase activity
JRI60_RS45910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JRI60_RS45925	COG2031	fatty acid transporter
JRI60_RS45935	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JRI60_RS45950	COG1278	Cold shock
JRI60_RS45980	COG1309	transcriptional regulator
JRI60_RS45990	COG1234	tRNA 3'-trailer cleavage
JRI60_RS46015	COG0596	Alpha beta hydrolase
JRI60_RS46050	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JRI60_RS46125	COG1764	response to oxidative stress
JRI60_RS46135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRI60_RS46150	COG5002	protein histidine kinase activity
JRI60_RS46165	COG2205	protein histidine kinase activity
JRI60_RS46210	COG2205	protein histidine kinase activity
JRI60_RS46215	COG0667	Aldo Keto reductase
JRI60_RS46220	COG1405	negative regulation of cell septum assembly
JRI60_RS46220	COG3012	SEC-C Motif Domain Protein
JRI60_RS46245	COG1131	(ABC) transporter
JRI60_RS46250	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JRI60_RS46270	COG1192	Involved in chromosome partitioning
JRI60_RS46280	COG1396	sequence-specific DNA binding
JRI60_RS46300	COG1309	transcriptional regulator
JRI60_RS46320	COG3265	gluconokinase activity
JRI60_RS46345	COG0110	maltose O-acetyltransferase activity
JRI60_RS46365	COG0671	phosphoesterase, PA-phosphatase related
JRI60_RS46375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JRI60_RS46405	COG1612	heme a metabolic process
JRI60_RS46405	COG0109	protoheme IX farnesyltransferase activity
JRI60_RS46415	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS46415	COG1672	PFAM Archaeal ATPase
JRI60_RS46450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JRI60_RS46450	COG0574	Belongs to the PEP-utilizing enzyme family
JRI60_RS46470	COG1174	glycine betaine transport
JRI60_RS46475	COG1125	glycine betaine transport
JRI60_RS46475	COG0517	IMP dehydrogenase activity
JRI60_RS46490	COG1525	nuclease
JRI60_RS46505	COG2819	hydrolase of the alpha beta superfamily
JRI60_RS46515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JRI60_RS46525	COG0438	transferase activity, transferring glycosyl groups
JRI60_RS46530	COG0488	(ABC) transporter
JRI60_RS46540	COG1131	(ABC) transporter
JRI60_RS46545	COG0842	Transport permease protein
JRI60_RS46550	COG0515	serine threonine protein kinase
JRI60_RS46555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JRI60_RS46565	COG2252	PERMEase
JRI60_RS46570	COG0784	Response regulator, receiver
JRI60_RS46570	COG4191	Histidine kinase
JRI60_RS46585	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JRI60_RS46640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRI60_RS46650	COG0551	DNA topoisomerase type I activity
JRI60_RS46650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JRI60_RS46670	COG0436	Aminotransferase
JRI60_RS46695	COG4251	negative regulation of phosphorylation
JRI60_RS46715	COG4774	siderophore transport
JRI60_RS46720	COG3128	pkhd-type hydroxylase
JRI60_RS46730	COG5002	protein histidine kinase activity
JRI60_RS46740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_RS46745	COG0745	RESPONSE REGULATOR receiver
JRI60_RS46770	COG2182	Extracellular solute-binding protein
JRI60_RS46775	COG4191	Histidine kinase
JRI60_RS46780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JRI60_RS46785	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS46820	COG4771	TonB-dependent receptor
JRI60_RS46825	COG0515	serine threonine protein kinase
JRI60_RS46830	COG1132	(ABC) transporter
JRI60_RS46835	COG1132	(ABC) transporter
JRI60_RS46850	COG2816	NAD+ diphosphatase activity
JRI60_RS46855	COG0602	queuosine metabolic process
JRI60_RS46875	COG1121	(ABC) transporter
JRI60_RS46885	COG2827	Endonuclease containing a URI domain
JRI60_RS46900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRI60_RS46905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRI60_RS46910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRI60_RS46915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JRI60_RS46935	COG0745	RESPONSE REGULATOR receiver
JRI60_RS46970	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JRI60_RS46985	COG1309	transcriptional regulator
JRI60_RS47025	COG0765	amino acid transport
JRI60_RS47030	COG1126	abc transporter atp-binding protein
JRI60_RS47035	COG3387	PFAM Glycoside hydrolase 15-related
JRI60_RS47050	COG3321	synthase
JRI60_RS47050	COG0604	alcohol dehydrogenase
JRI60_RS47090	COG2843	Capsule synthesis protein
JRI60_RS47100	COG0386	Belongs to the glutathione peroxidase family
JRI60_RS47115	COG1309	transcriptional regulator
JRI60_RS47145	COG0515	serine threonine protein kinase
JRI60_RS47145	COG2815	serine threonine protein kinase
JRI60_RS47160	COG0625	glutathione transferase activity
JRI60_RS47165	COG1215	transferase activity, transferring glycosyl groups
JRI60_RS47170	COG5000	phosphorelay sensor kinase activity
JRI60_RS47205	COG0346	lactoylglutathione lyase activity
JRI60_RS47220	COG2267	carboxylic ester hydrolase activity
JRI60_RS47240	COG2204	response regulator
JRI60_RS47245	COG5000	phosphorelay sensor kinase activity
JRI60_RS47270	COG0515	serine threonine protein kinase
JRI60_RS47270	COG2815	serine threonine protein kinase
JRI60_RS47275	COG0745	RESPONSE REGULATOR receiver
JRI60_RS47280	COG0745	RESPONSE REGULATOR receiver
JRI60_RS47285	COG0166	Belongs to the GPI family
JRI60_RS47295	COG2124	cytochrome p450
JRI60_RS47315	COG0515	serine threonine protein kinase
JRI60_RS47320	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS47325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_RS47330	COG3844	kynureninase activity
JRI60_RS47340	COG0662	Cupin 2, conserved barrel domain protein
JRI60_RS47365	COG0840	transmembrane signaling receptor activity
JRI60_RS47415	COG2205	protein histidine kinase activity
JRI60_RS47415	COG4999	Histidine kinase
JRI60_RS47415	COG3850	Histidine kinase
JRI60_RS47415	COG3437	response regulator, receiver
JRI60_RS47460	COG1404	Belongs to the peptidase S8 family
JRI60_RS47500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JRI60_RS47530	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JRI60_RS47545	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_RS47565	COG2205	protein histidine kinase activity
JRI60_RS47565	COG0784	Response regulator, receiver
JRI60_RS47570	COG2815	serine threonine protein kinase
JRI60_RS47570	COG0515	serine threonine protein kinase
JRI60_RS47600	COG1408	metallophosphoesterase
JRI60_RS47630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JRI60_RS47635	COG0372	Belongs to the citrate synthase family
JRI60_RS47665	COG1337	RAMP superfamily
JRI60_RS47705	COG2815	serine threonine protein kinase
JRI60_RS47705	COG0515	serine threonine protein kinase
JRI60_RS47715	COG0012	GTP binding
JRI60_RS47720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JRI60_RS47725	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JRI60_RS47730	COG0356	it plays a direct role in the translocation of protons across the membrane
JRI60_RS47755	COG1881	PFAM PEBP family protein
JRI60_RS47760	COG3852	Histidine kinase
JRI60_RS47790	COG1595	DNA-templated transcription, initiation
JRI60_RS47835	COG2124	cytochrome p450
JRI60_RS47870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JRI60_RS47875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JRI60_RS47890	COG2205	protein histidine kinase activity
JRI60_RS47930	COG0640	Transcriptional regulator
JRI60_RS47935	COG1902	pentaerythritol trinitrate reductase activity
JRI60_RS47945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JRI60_RS47975	COG0753	catalase activity
JRI60_RS48060	COG2205	protein histidine kinase activity
JRI60_RS48115	COG0583	DNA-binding transcription factor activity
JRI60_RS48135	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS48185	COG2204	response regulator
JRI60_RS48190	COG0596	Alpha beta hydrolase
JRI60_RS48195	COG1515	deoxyribonuclease V activity
JRI60_RS48205	COG0515	serine threonine protein kinase
JRI60_RS48225	COG2814	Major facilitator Superfamily
JRI60_RS48230	COG0631	protein serine/threonine phosphatase activity
JRI60_RS48240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JRI60_RS48270	COG2205	protein histidine kinase activity
JRI60_RS48280	COG2172	sigma factor antagonist activity
JRI60_RS48285	COG1366	Belongs to the anti-sigma-factor antagonist family
JRI60_RS48290	COG1366	Belongs to the anti-sigma-factor antagonist family
JRI60_RS48295	COG0515	serine threonine protein kinase
JRI60_RS48300	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JRI60_RS48345	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JRI60_RS48360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JRI60_RS48365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JRI60_RS48385	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JRI60_RS48420	COG2204	response regulator
JRI60_RS48425	COG0189	ligase activity
JRI60_RS48460	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_RS48485	COG2155	Conserved Protein
JRI60_RS48490	COG4946	Tricorn protease homolog
JRI60_RS48490	COG1506	peptidase
JRI60_RS48490	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_RS48535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_RS48540	COG2205	protein histidine kinase activity
JRI60_RS48565	COG1196	nuclear chromosome segregation
JRI60_RS48590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JRI60_RS48600	COG2339	peptidase activity
JRI60_RS48635	COG1408	metallophosphoesterase
JRI60_RS48660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_RS48665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_RS48690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JRI60_RS48700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JRI60_RS48700	COG4191	Histidine kinase
JRI60_RS48705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS48720	COG0515	serine threonine protein kinase
JRI60_RS48725	COG0443	Heat shock 70 kDa protein
JRI60_RS48775	COG2319	Wd-40 repeat
JRI60_RS48775	COG4249	Peptidase C14 caspase catalytic subunit p20
JRI60_RS48840	COG0515	serine threonine protein kinase
JRI60_RS48840	COG2815	serine threonine protein kinase
JRI60_RS48875	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_RS48890	COG2205	protein histidine kinase activity
JRI60_RS49010	COG5507	3-demethylubiquinone-9 3-methyltransferase
JRI60_RS49035	COG1643	Atp-dependent helicase
JRI60_RS49060	COG1196	nuclear chromosome segregation
JRI60_RS49090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JRI60_RS49115	COG2133	pyrroloquinoline quinone binding
JRI60_RS49125	COG0583	DNA-binding transcription factor activity
JRI60_RS49210	COG0247	lactate metabolic process
JRI60_RS49210	COG2181	nitrate reductase activity
JRI60_RS49215	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_RS49230	COG3437	response regulator, receiver
JRI60_RS49230	COG4999	Histidine kinase
JRI60_RS49230	COG2205	protein histidine kinase activity
JRI60_RS49230	COG3850	Histidine kinase
JRI60_RS49235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JRI60_RS49260	COG0848	biopolymer transport protein
JRI60_RS49280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_RS49300	COG0515	serine threonine protein kinase
JRI60_RS49320	COG0745	RESPONSE REGULATOR receiver
JRI60_RS49325	COG5002	protein histidine kinase activity
JRI60_RS49330	COG0784	Response regulator, receiver
JRI60_RS49335	COG4251	negative regulation of phosphorylation
JRI60_RS49350	COG0515	serine threonine protein kinase
JRI60_RS49365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JRI60_RS49385	COG4106	trans-aconitate 2-methyltransferase activity
JRI60_RS49400	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JRI60_RS49405	COG3387	PFAM Glycoside hydrolase 15-related
JRI60_RS49425	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS49445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JRI60_RS49500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRI60_RS49515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_RS49535	COG3186	Phenylalanine-4-hydroxylase
JRI60_RS49540	COG2072	flavoprotein involved in K transport
JRI60_RS49545	COG0657	acetylesterase activity
JRI60_RS49600	COG0625	glutathione transferase activity
JRI60_RS49605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JRI60_RS49605	COG2169	Transcriptional regulator
JRI60_RS49610	COG0667	Aldo Keto reductase
JRI60_RS49630	COG0640	Transcriptional regulator
JRI60_RS49635	COG0625	glutathione transferase activity
JRI60_RS49640	COG0583	DNA-binding transcription factor activity
JRI60_RS49695	COG2205	protein histidine kinase activity
JRI60_RS49710	COG2205	protein histidine kinase activity
JRI60_RS49750	COG4191	Histidine kinase
JRI60_RS49775	COG5002	protein histidine kinase activity
JRI60_RS49780	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS49780	COG1672	PFAM Archaeal ATPase
JRI60_RS49810	COG0640	Transcriptional regulator
JRI60_RS49835	COG0582	viral genome integration into host DNA
JRI60_RS49875	COG3344	reverse transcriptase
JRI60_RS49905	COG4372	Transposase
JRI60_RS49945	COG0024	Methionine aminopeptidase
JRI60_RS49955	COG2207	Transcriptional regulator
JRI60_RS49960	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JRI60_RS50000	COG0515	serine threonine protein kinase
JRI60_RS50000	COG2815	serine threonine protein kinase
JRI60_RS50100	COG2267	carboxylic ester hydrolase activity
JRI60_RS50115	COG2207	Transcriptional regulator
JRI60_RS50130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JRI60_RS50160	COG0657	acetylesterase activity
JRI60_RS50165	COG2815	serine threonine protein kinase
JRI60_RS50165	COG0515	serine threonine protein kinase
JRI60_RS50190	COG4257	antibiotic catabolic process
JRI60_RS50210	COG1595	DNA-templated transcription, initiation
JRI60_RS50215	COG0515	serine threonine protein kinase
JRI60_RS50240	COG0515	serine threonine protein kinase
JRI60_RS50255	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_RS50265	COG0583	DNA-binding transcription factor activity
JRI60_RS50285	COG2124	cytochrome p450
JRI60_RS50290	COG1131	(ABC) transporter
JRI60_RS50295	COG0842	Transport permease protein
JRI60_RS50310	COG0515	serine threonine protein kinase
JRI60_RS50335	COG4566	intracellular signal transduction
JRI60_RS50340	COG4566	intracellular signal transduction
JRI60_RS50355	COG2267	carboxylic ester hydrolase activity
JRI60_RS50360	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS50390	COG0644	oxidoreductase
JRI60_RS50430	COG1960	acyl-CoA dehydrogenase activity
JRI60_RS50500	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS50505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_RS50515	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS50530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JRI60_RS50540	COG2226	methyltransferase
JRI60_RS50555	COG2267	carboxylic ester hydrolase activity
JRI60_RS50560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JRI60_RS50565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JRI60_RS50570	COG5002	protein histidine kinase activity
JRI60_RS50570	COG2205	protein histidine kinase activity
JRI60_RS50570	COG0784	Response regulator, receiver
JRI60_RS50575	COG5002	protein histidine kinase activity
JRI60_RS50635	COG1764	response to oxidative stress
JRI60_RS50640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JRI60_RS50645	COG1846	Transcriptional regulator
JRI60_RS50705	COG0583	DNA-binding transcription factor activity
JRI60_RS50755	COG0435	Glutathione S-transferase
JRI60_RS50760	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS50760	COG1672	PFAM Archaeal ATPase
JRI60_RS50765	COG0446	pyridine nucleotide-disulphide oxidoreductase
JRI60_RS50770	COG2204	response regulator
JRI60_RS50780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JRI60_RS50785	COG0730	response to heat
JRI60_RS50805	COG3268	Saccharopine dehydrogenase
JRI60_RS50835	COG3311	Transcriptional regulator
JRI60_RS50840	COG5002	protein histidine kinase activity
JRI60_RS50845	COG2205	protein histidine kinase activity
JRI60_RS50850	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JRI60_RS50860	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JRI60_RS50870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRI60_RS50875	COG3228	Belongs to the MtfA family
JRI60_RS50890	COG0288	reversible hydration of carbon dioxide
JRI60_RS50945	COG2267	carboxylic ester hydrolase activity
JRI60_RS50960	COG4221	oxidoreductase activity
JRI60_RS50970	COG0596	Alpha beta hydrolase
JRI60_RS51000	COG5000	phosphorelay sensor kinase activity
JRI60_RS51020	COG0673	inositol 2-dehydrogenase activity
JRI60_RS51045	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JRI60_RS51055	COG5464	transposase or invertase
JRI60_RS51095	COG5632	N-Acetylmuramoyl-L-alanine amidase
JRI60_RS51095	COG3409	Peptidoglycan-binding domain 1 protein
JRI60_RS51095	COG1388	LysM domain
JRI60_RS51140	COG2124	cytochrome p450
JRI60_RS51150	COG1672	PFAM Archaeal ATPase
JRI60_RS51150	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_RS51165	COG3540	Alkaline phosphatase
JRI60_RS51195	COG0038	chloride channel
JRI60_RS51205	COG0346	lactoylglutathione lyase activity
JRI60_RS51230	COG0346	lactoylglutathione lyase activity
JRI60_RS51260	COG0515	serine threonine protein kinase
JRI60_RS51260	COG2815	serine threonine protein kinase
JRI60_RS51270	COG2885	chlorophyll binding
JRI60_RS51270	COG3047	cAMP biosynthetic process
JRI60_RS51310	COG0281	malic enzyme
JRI60_RS51315	COG2205	protein histidine kinase activity
JRI60_RS51360	COG4191	Histidine kinase
JRI60_RS51360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JRI60_RS51395	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_RS51455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JRI60_RS51520	COG0745	RESPONSE REGULATOR receiver
JRI60_RS51565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_RS51585	COG0154	amidase activity
JRI60_RS51600	COG0589	response to stress
JRI60_RS51610	COG3550	peptidyl-serine autophosphorylation
JRI60_RS51620	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JRI60_RS51620	COG2755	lipolytic protein G-D-S-L family
JRI60_RS51640	COG0778	Nitroreductase
JRI60_RS51645	COG0492	ferredoxin-NADP+ reductase activity
JRI60_RS51665	COG0515	serine threonine protein kinase
JRI60_RS51685	COG2321	neutral zinc metallopeptidase
JRI60_RS51695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_RS51700	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JRI60_RS51705	COG0544	peptidyl-prolyl cis-trans isomerase activity
JRI60_RS51720	COG0596	Alpha beta hydrolase
JRI60_RS51725	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_RS51730	COG1942	4-Oxalocrotonate Tautomerase
JRI60_RS51750	COG0352	thiamine-phosphate diphosphorylase activity
JRI60_RS51755	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JRI60_RS51820	COG4946	Tricorn protease homolog
JRI60_RS51820	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_RS51820	COG1506	peptidase
JRI60_RS51840	COG2815	serine threonine protein kinase
JRI60_RS51840	COG0515	serine threonine protein kinase
JRI60_RS51845	COG4191	Histidine kinase
JRI60_RS51905	COG2815	serine threonine protein kinase
JRI60_RS51905	COG0515	serine threonine protein kinase
JRI60_RS51930	COG1690	Belongs to the RtcB family
JRI60_RS51955	COG2234	aminopeptidase activity
JRI60_RS51995	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JRI60_RS52025	COG0515	serine threonine protein kinase
JRI60_RS52025	COG2815	serine threonine protein kinase
JRI60_RS52060	COG3387	PFAM Glycoside hydrolase 15-related
JRI60_RS52080	COG0477	Major facilitator Superfamily
JRI60_RS52085	COG0784	Response regulator, receiver
JRI60_RS52110	COG0515	serine threonine protein kinase
JRI60_RS52155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_RS52165	COG0667	Aldo Keto reductase
JRI60_RS52200	COG0515	serine threonine protein kinase
JRI60_RS52240	COG0515	serine threonine protein kinase
JRI60_RS52285	COG0189	ligase activity
JRI60_RS52290	COG1136	(ABC) transporter
JRI60_RS52320	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JRI60_RS52340	COG3214	Protein conserved in bacteria
JRI60_RS52355	COG0515	serine threonine protein kinase
JRI60_RS52355	COG2815	serine threonine protein kinase
JRI60_RS52480	COG2815	serine threonine protein kinase
JRI60_RS52480	COG0515	serine threonine protein kinase
JRI60_RS52485	COG2814	Major facilitator Superfamily
JRI60_RS52515	COG1752	Esterase of the alpha-beta hydrolase superfamily
JRI60_RS52545	COG3409	Peptidoglycan-binding domain 1 protein
JRI60_RS52570	COG2226	methyltransferase
JRI60_RS52575	COG2205	protein histidine kinase activity
JRI60_RS52615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JRI60_RS52620	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JRI60_RS52625	COG0594	ribonuclease P activity
JRI60_RS52630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JRI60_RS52635	COG0706	membrane insertase activity
JRI60_RS52650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JRI60_RS52670	COG0702	epimerase
JRI60_RS52715	COG0616	signal peptide processing
JRI60_RS52720	COG2267	carboxylic ester hydrolase activity
JRI60_RS52735	COG0612	Peptidase, M16
JRI60_RS52740	COG2226	methyltransferase
JRI60_RS52745	COG1104	cysteine desulfurase activity
JRI60_RS52760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JRI60_RS52765	COG0537	adenosine 5'-monophosphoramidase activity
JRI60_RS52790	COG0515	serine threonine protein kinase