locus-tag	class	description
AANAER_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AANAER_RS00010	COG0592	DNA-directed DNA polymerase activity
AANAER_RS00015	COG0187	DNA topoisomerase II activity
AANAER_RS00055	COG1280	lysine exporter protein (LysE YggA)
AANAER_RS00075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AANAER_RS00095	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AANAER_RS00100	COG0830	nickel cation binding
AANAER_RS00105	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AANAER_RS00110	COG0804	urea catabolic process
AANAER_RS00115	COG0831	urea catabolic process
AANAER_RS00115	COG0832	Belongs to the urease beta subunit family
AANAER_RS00120	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AANAER_RS00125	COG1953	Uracil, thiamine, allantoin
AANAER_RS00135	COG4266	Belongs to the allantoicase family
AANAER_RS00170	COG4177	L-phenylalanine transmembrane transporter activity
AANAER_RS00180	COG0683	leucine binding
AANAER_RS00195	COG4120	Belongs to the binding-protein-dependent transport system permease family
AANAER_RS00200	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AANAER_RS00205	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AANAER_RS00210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AANAER_RS00220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AANAER_RS00235	COG0829	nickel cation binding
AANAER_RS00280	COG0745	RESPONSE REGULATOR receiver
AANAER_RS00295	COG0840	transmembrane signaling receptor activity
AANAER_RS00305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AANAER_RS00315	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AANAER_RS00340	COG1053	succinate dehydrogenase
AANAER_RS00350	COG0157	Belongs to the NadC ModD family
AANAER_RS00360	COG4208	sulfate ABC transporter
AANAER_RS00370	COG3842	ATPase activity
AANAER_RS00395	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AANAER_RS00400	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AANAER_RS00410	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AANAER_RS00415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AANAER_RS00425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AANAER_RS00430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AANAER_RS00435	COG0633	Ferredoxin
AANAER_RS00455	COG0716	FMN binding
AANAER_RS00485	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AANAER_RS00495	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AANAER_RS00505	COG0628	permease
AANAER_RS00515	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AANAER_RS00525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AANAER_RS00540	COG0426	domain, Protein
AANAER_RS00560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AANAER_RS00590	COG0564	pseudouridine synthase activity
AANAER_RS00595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AANAER_RS00600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AANAER_RS00605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AANAER_RS00610	COG0697	spore germination
AANAER_RS00630	COG1280	lysine exporter protein (LysE YggA)
AANAER_RS00650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AANAER_RS00655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AANAER_RS00660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AANAER_RS00665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AANAER_RS00670	COG1280	lysine exporter protein (LysE YggA)
AANAER_RS00675	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AANAER_RS00680	COG3118	belongs to the thioredoxin family
AANAER_RS00685	COG1733	regulation of RNA biosynthetic process
AANAER_RS00690	COG0604	alcohol dehydrogenase
AANAER_RS00695	COG1733	regulation of RNA biosynthetic process
AANAER_RS00700	COG0390	transport system, permease component
AANAER_RS00705	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AANAER_RS00720	COG0277	FAD linked oxidase domain protein
AANAER_RS00735	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AANAER_RS00740	COG0745	RESPONSE REGULATOR receiver
AANAER_RS00745	COG4191	Histidine kinase
AANAER_RS00750	COG1556	Lactate utilization protein
AANAER_RS00755	COG1139	Iron-sulfur cluster binding protein
AANAER_RS00760	COG0247	lactate metabolic process
AANAER_RS00765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AANAER_RS00770	COG0511	ligase activity, forming carbon-carbon bonds
AANAER_RS00775	COG0439	Biotin carboxylase
AANAER_RS00780	COG0513	Belongs to the DEAD box helicase family
AANAER_RS00795	COG0306	phosphate transporter
AANAER_RS00805	COG0367	asparagine synthase
AANAER_RS00820	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AANAER_RS00840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AANAER_RS00845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AANAER_RS00850	COG1981	membrane
AANAER_RS00855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AANAER_RS00855	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AANAER_RS00860	COG1187	pseudouridine synthase activity
AANAER_RS00865	COG0517	IMP dehydrogenase activity
AANAER_RS00865	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AANAER_RS00870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AANAER_RS00875	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AANAER_RS00880	COG0107	imidazoleglycerol-phosphate synthase activity
AANAER_RS00895	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AANAER_RS00900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AANAER_RS00905	COG0724	RNA recognition motif
AANAER_RS00930	COG0642	Histidine kinase
AANAER_RS00935	COG0745	RESPONSE REGULATOR receiver
AANAER_RS00940	COG0642	Histidine kinase
AANAER_RS00945	COG0745	RESPONSE REGULATOR receiver
AANAER_RS00950	COG2353	YceI-like domain
AANAER_RS00955	COG0534	Mate efflux family protein
AANAER_RS00960	COG0460	homoserine dehydrogenase
AANAER_RS00965	COG0436	Aminotransferase
AANAER_RS00975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AANAER_RS00980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AANAER_RS00985	COG0254	rRNA binding
AANAER_RS00990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AANAER_RS00995	COG0109	protoheme IX farnesyltransferase activity
AANAER_RS01025	COG1794	racemase activity, acting on amino acids and derivatives
AANAER_RS01040	COG0745	RESPONSE REGULATOR receiver
AANAER_RS01045	COG5000	phosphorelay sensor kinase activity
AANAER_RS01050	COG0243	molybdopterin cofactor binding
AANAER_RS01055	COG0437	4 iron, 4 sulfur cluster binding
AANAER_RS01060	COG3302	dmso reductase anchor subunit
AANAER_RS01070	COG0659	secondary active sulfate transmembrane transporter activity
AANAER_RS01090	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AANAER_RS01095	COG2992	FlgJ-related protein
AANAER_RS01100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AANAER_RS01105	COG0237	dephospho-CoA kinase activity
AANAER_RS01110	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AANAER_RS01115	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AANAER_RS01120	COG1741	Belongs to the pirin family
AANAER_RS01150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AANAER_RS01155	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AANAER_RS01160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AANAER_RS01170	COG0505	Belongs to the CarA family
AANAER_RS01185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AANAER_RS01185	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AANAER_RS01195	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AANAER_RS01200	COG0489	protein tyrosine kinase activity
AANAER_RS01205	COG0735	belongs to the Fur family
AANAER_RS01210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AANAER_RS01215	COG1129	ABC transporter
AANAER_RS01215	COG0842	Transport permease protein
AANAER_RS01220	COG0842	Transport permease protein
AANAER_RS01225	COG0140	phosphoribosyl-ATP diphosphatase activity
AANAER_RS01225	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AANAER_RS01250	COG1410	methionine synthase
AANAER_RS01250	COG0646	methionine synthase
AANAER_RS01260	COG3647	Membrane
AANAER_RS01295	COG1854	S-ribosylhomocysteine lyase activity
AANAER_RS01310	COG3287	FIST C domain
AANAER_RS01310	COG2200	EAL domain
AANAER_RS01310	COG2199	diguanylate cyclase activity
AANAER_RS01315	COG1013	pyruvate-flavodoxin oxidoreductase activity
AANAER_RS01320	COG0674	pyruvate-flavodoxin oxidoreductase activity
AANAER_RS01325	COG1144	Oxidoreductase
AANAER_RS01330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AANAER_RS01340	COG0546	phosphoglycolate phosphatase activity
AANAER_RS01355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AANAER_RS01360	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AANAER_RS01365	COG3850	Histidine kinase
AANAER_RS01365	COG5002	protein histidine kinase activity
AANAER_RS01370	COG0745	RESPONSE REGULATOR receiver
AANAER_RS01385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AANAER_RS01390	COG0581	inorganic phosphate transmembrane transporter activity
AANAER_RS01395	COG0573	inorganic phosphate transmembrane transporter activity
AANAER_RS01400	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AANAER_RS01405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AANAER_RS01410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AANAER_RS01415	COG0268	Binds directly to 16S ribosomal RNA
AANAER_RS01420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AANAER_RS01425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AANAER_RS01430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AANAER_RS01435	COG0746	molybdenum cofactor guanylyltransferase activity
AANAER_RS01440	COG0446	pyridine nucleotide-disulphide oxidoreductase
AANAER_RS01485	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AANAER_RS01490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AANAER_RS01495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AANAER_RS01530	COG0575	Belongs to the CDS family
AANAER_RS01535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AANAER_RS01555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AANAER_RS01565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AANAER_RS01565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AANAER_RS01570	COG1324	tolerance protein
AANAER_RS01575	COG2022	thiamine diphosphate biosynthetic process
AANAER_RS01590	COG2207	Transcriptional regulator
AANAER_RS01590	COG1917	Cupin 2, conserved barrel domain protein
AANAER_RS01630	COG1309	transcriptional regulator
AANAER_RS01640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AANAER_RS01650	COG0783	Belongs to the Dps family
AANAER_RS01655	COG0574	Belongs to the PEP-utilizing enzyme family
AANAER_RS01655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AANAER_RS01680	COG0837	glucose binding
AANAER_RS01705	COG0585	pseudouridine synthase activity
AANAER_RS01710	COG3706	GGDEF domain
AANAER_RS01715	COG4191	Histidine kinase
AANAER_RS01730	COG0793	Belongs to the peptidase S41A family
AANAER_RS01735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AANAER_RS01740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AANAER_RS01745	COG0047	phosphoribosylformylglycinamidine synthase activity
AANAER_RS01755	COG0204	Acyl-transferase
AANAER_RS01760	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AANAER_RS01770	COG0018	arginyl-trna synthetase
AANAER_RS01780	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AANAER_RS01790	COG0126	phosphoglycerate kinase activity
AANAER_RS01795	COG0149	triose-phosphate isomerase activity
AANAER_RS01800	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AANAER_RS01805	COG0019	diaminopimelate decarboxylase activity
AANAER_RS01815	COG0077	Prephenate dehydratase
AANAER_RS01815	COG1605	Chorismate mutase
AANAER_RS01820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AANAER_RS01825	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AANAER_RS01840	COG0424	maF-like protein
AANAER_RS01855	COG0791	NLP P60 protein
AANAER_RS01860	COG0791	NLP P60 protein
AANAER_RS01870	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS01875	COG3261	NADH dehydrogenase
AANAER_RS01875	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AANAER_RS01885	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS01895	COG2111	Na H antiporter
AANAER_RS01895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AANAER_RS01900	COG1276	copper resistance
AANAER_RS01905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AANAER_RS01910	COG3118	belongs to the thioredoxin family
AANAER_RS01915	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AANAER_RS01920	COG4191	Histidine kinase
AANAER_RS01925	COG0745	RESPONSE REGULATOR receiver
AANAER_RS01930	COG0745	RESPONSE REGULATOR receiver
AANAER_RS01935	COG3852	Histidine kinase
AANAER_RS01940	COG0252	asparaginase activity
AANAER_RS01945	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AANAER_RS01950	COG1027	Aspartate ammonia-lyase
AANAER_RS01960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AANAER_RS01965	COG1053	succinate dehydrogenase
AANAER_RS01975	COG1115	amino acid carrier protein
AANAER_RS01980	COG0492	ferredoxin-NADP+ reductase activity
AANAER_RS01985	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AANAER_RS01990	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AANAER_RS01995	COG1242	4 iron, 4 sulfur cluster binding
AANAER_RS02005	COG0210	DNA helicase
AANAER_RS02010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AANAER_RS02015	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AANAER_RS02020	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AANAER_RS02025	COG3278	Belongs to the heme-copper respiratory oxidase family
AANAER_RS02060	COG2887	Belongs to the helicase family. UvrD subfamily
AANAER_RS02065	COG4773	Receptor
AANAER_RS02070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AANAER_RS02080	COG4773	Receptor
AANAER_RS02090	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AANAER_RS02100	COG0157	Belongs to the NadC ModD family
AANAER_RS02115	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AANAER_RS02125	COG0083	homoserine kinase activity
AANAER_RS02135	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AANAER_RS02140	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AANAER_RS02145	COG0779	Required for maturation of 30S ribosomal subunits
AANAER_RS02150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AANAER_RS02150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AANAER_RS02165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AANAER_RS02170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AANAER_RS02175	COG1185	polyribonucleotide nucleotidyltransferase activity
AANAER_RS02175	COG0539	negative regulation of cytoplasmic translation
AANAER_RS02180	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AANAER_RS02185	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AANAER_RS02190	COG0072	phenylalanine-tRNA ligase activity
AANAER_RS02190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AANAER_RS02195	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AANAER_RS02200	COG0537	adenosine 5'-monophosphoramidase activity
AANAER_RS02205	COG0825	malonyl-CoA metabolic process
AANAER_RS02210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AANAER_RS02215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AANAER_RS02235	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AANAER_RS02240	COG0303	'Molybdopterin
AANAER_RS02265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AANAER_RS02270	COG0723	plastoquinol--plastocyanin reductase activity
AANAER_RS02275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AANAER_RS02280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AANAER_RS02290	COG1074	ATP-dependent DNA helicase activity
AANAER_RS02300	COG0356	it plays a direct role in the translocation of protons across the membrane
AANAER_RS02305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AANAER_RS02315	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AANAER_RS02325	COG0336	Belongs to the RNA methyltransferase TrmD family
AANAER_RS02330	COG0335	large ribosomal subunit rRNA binding
AANAER_RS02350	COG1126	abc transporter atp-binding protein
AANAER_RS02355	COG0765	amino acid transport
AANAER_RS02360	COG0765	amino acid transport
AANAER_RS02365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AANAER_RS02370	COG0784	Response regulator, receiver
AANAER_RS02370	COG4191	Histidine kinase
AANAER_RS02375	COG0450	alkyl hydroperoxide reductase
AANAER_RS02380	COG0586	Pfam SNARE associated Golgi protein
AANAER_RS02385	COG4221	oxidoreductase activity
AANAER_RS02395	COG2198	Histidine kinase
AANAER_RS02395	COG0643	Histidine kinase
AANAER_RS02405	COG2201	protein-glutamate methylesterase activity
AANAER_RS02410	COG3706	GGDEF domain
AANAER_RS02425	COG2966	Psort location CytoplasmicMembrane, score
AANAER_RS02450	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AANAER_RS02460	COG3204	pilus organization
AANAER_RS02490	COG0848	biopolymer transport protein
AANAER_RS02495	COG0811	peptide transport
AANAER_RS02500	COG0811	peptide transport
AANAER_RS02540	COG4773	Receptor
AANAER_RS02545	COG2207	Transcriptional regulator
AANAER_RS02545	COG4753	response regulator
AANAER_RS02550	COG2205	protein histidine kinase activity
AANAER_RS02555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AANAER_RS02565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AANAER_RS02570	COG4773	Receptor
AANAER_RS02600	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AANAER_RS02605	COG2199	diguanylate cyclase activity
AANAER_RS02605	COG2200	EAL domain
AANAER_RS02605	COG3287	FIST C domain
AANAER_RS02615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AANAER_RS02620	COG1280	lysine exporter protein (LysE YggA)
AANAER_RS02625	COG1126	abc transporter atp-binding protein
AANAER_RS02630	COG0765	amino acid transport
AANAER_RS02635	COG4597	amino acid ABC transporter
AANAER_RS02640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AANAER_RS02650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AANAER_RS02660	COG1119	ATPase activity
AANAER_RS02665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AANAER_RS02675	COG2404	hydrolase activity, acting on ester bonds
AANAER_RS02680	COG0288	reversible hydration of carbon dioxide
AANAER_RS02685	COG0439	Biotin carboxylase
AANAER_RS02695	COG2197	response regulator
AANAER_RS02720	COG3328	transposase activity
AANAER_RS02735	COG0642	Histidine kinase
AANAER_RS02740	COG0745	RESPONSE REGULATOR receiver
AANAER_RS02745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AANAER_RS02750	COG0191	fructose-bisphosphate aldolase activity
AANAER_RS02755	COG0848	biopolymer transport protein
AANAER_RS02775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AANAER_RS02780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AANAER_RS02790	COG0142	geranyltranstransferase activity
AANAER_RS02795	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AANAER_RS02800	COG0442	prolyl-tRNA aminoacylation
AANAER_RS02805	COG0668	transmembrane transport
AANAER_RS02810	COG0617	tRNA 3'-terminal CCA addition
AANAER_RS02815	COG0668	transmembrane transport
AANAER_RS02820	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AANAER_RS02825	COG1862	Preprotein translocase
AANAER_RS02830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AANAER_RS02835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AANAER_RS02855	COG0495	leucyl-tRNA aminoacylation
AANAER_RS02865	COG0285	dihydrofolate synthase activity
AANAER_RS02870	COG0739	heme binding
AANAER_RS02900	COG1136	(ABC) transporter
AANAER_RS02900	COG0577	efflux transmembrane transporter activity
AANAER_RS02905	COG1136	(ABC) transporter
AANAER_RS02905	COG0577	efflux transmembrane transporter activity
AANAER_RS02915	COG4771	TonB-dependent receptor
AANAER_RS02935	COG0784	Response regulator, receiver
AANAER_RS02960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AANAER_RS02970	COG0745	RESPONSE REGULATOR receiver
AANAER_RS02975	COG0642	Histidine kinase
AANAER_RS02980	COG2081	HI0933 family
AANAER_RS02985	COG0840	transmembrane signaling receptor activity
AANAER_RS02990	COG2204	response regulator
AANAER_RS02995	COG3920	Histidine kinase
AANAER_RS03000	COG5000	phosphorelay sensor kinase activity
AANAER_RS03005	COG1692	metallophosphoesterase
AANAER_RS03030	COG1570	exodeoxyribonuclease VII activity
AANAER_RS03040	COG0840	transmembrane signaling receptor activity
AANAER_RS03050	COG0745	RESPONSE REGULATOR receiver
AANAER_RS03060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AANAER_RS03070	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AANAER_RS03075	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AANAER_RS03085	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AANAER_RS03090	COG0459	protein refolding
AANAER_RS03100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AANAER_RS03105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AANAER_RS03110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AANAER_RS03115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AANAER_RS03130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AANAER_RS03135	COG2264	protein methyltransferase activity
AANAER_RS03140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AANAER_RS03150	COG2205	protein histidine kinase activity
AANAER_RS03165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AANAER_RS03175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AANAER_RS03200	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AANAER_RS03205	COG3706	GGDEF domain
AANAER_RS03210	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AANAER_RS03215	COG0784	Response regulator, receiver
AANAER_RS03215	COG3437	response regulator, receiver
AANAER_RS03225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AANAER_RS03240	COG0745	RESPONSE REGULATOR receiver
AANAER_RS03245	COG0642	Histidine kinase
AANAER_RS03255	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AANAER_RS03265	COG0640	Transcriptional regulator
AANAER_RS03270	COG2217	Heavy metal translocating P-type atpase
AANAER_RS03280	COG0481	GTPase activity
AANAER_RS03290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AANAER_RS03295	COG2814	Major facilitator Superfamily
AANAER_RS03300	COG0482	sulfurtransferase activity
AANAER_RS03305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AANAER_RS03310	COG0006	proline dipeptidase activity
AANAER_RS03315	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AANAER_RS03320	COG0402	S-adenosylhomocysteine deaminase activity
AANAER_RS03330	COG3852	Histidine kinase
AANAER_RS03340	COG4263	nitrous-oxide reductase activity
AANAER_RS03355	COG0437	4 iron, 4 sulfur cluster binding
AANAER_RS03370	COG0348	domain, Protein
AANAER_RS03375	COG1131	(ABC) transporter
AANAER_RS03405	COG2151	metal-sulfur cluster biosynthetic enzyme
AANAER_RS03425	COG0513	Belongs to the DEAD box helicase family
AANAER_RS03435	COG0280	phosphate acetyltransferase
AANAER_RS03440	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AANAER_RS03445	COG0280	phosphate acetyltransferase
AANAER_RS03460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AANAER_RS03465	COG2176	DNA-directed DNA polymerase activity
AANAER_RS03475	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AANAER_RS03485	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AANAER_RS03495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AANAER_RS03505	COG0745	RESPONSE REGULATOR receiver
AANAER_RS03510	COG5002	protein histidine kinase activity
AANAER_RS03555	COG1058	Belongs to the CinA family
AANAER_RS03555	COG1546	Belongs to the CinA family
AANAER_RS03560	COG0579	oxidoreductase
AANAER_RS03565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AANAER_RS03580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AANAER_RS03605	COG0714	Associated with various cellular activities
AANAER_RS03615	COG0052	Belongs to the universal ribosomal protein uS2 family
AANAER_RS03620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AANAER_RS03625	COG1136	(ABC) transporter
AANAER_RS03635	COG0194	GDP metabolic process
AANAER_RS03640	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AANAER_RS03640	COG2199	diguanylate cyclase activity
AANAER_RS03645	COG2199	diguanylate cyclase activity
AANAER_RS03645	COG2200	EAL domain
AANAER_RS03645	COG3287	FIST C domain
AANAER_RS03650	COG2217	Heavy metal translocating P-type atpase
AANAER_RS03665	COG1124	(ABC) transporter
AANAER_RS03670	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AANAER_RS03685	COG1355	regulation of microtubule-based process
AANAER_RS03690	COG1121	(ABC) transporter
AANAER_RS03695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AANAER_RS03700	COG2996	Protein conserved in bacteria
AANAER_RS03705	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AANAER_RS03715	COG0210	DNA helicase
AANAER_RS03720	COG0525	valine-tRNA ligase activity
AANAER_RS03730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AANAER_RS03740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AANAER_RS03760	COG2814	Major facilitator Superfamily
AANAER_RS03765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AANAER_RS03790	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AANAER_RS03795	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AANAER_RS03810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AANAER_RS03825	COG3852	Histidine kinase
AANAER_RS03830	COG0668	transmembrane transport
AANAER_RS03850	COG0716	FMN binding
AANAER_RS03860	COG2200	EAL domain
AANAER_RS03860	COG3287	FIST C domain
AANAER_RS03860	COG2199	diguanylate cyclase activity
AANAER_RS03880	COG1858	cytochrome C peroxidase
AANAER_RS03960	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AANAER_RS03960	COG1918	ferrous iron import across plasma membrane
AANAER_RS03965	COG1918	ferrous iron import across plasma membrane
AANAER_RS03975	COG2205	protein histidine kinase activity
AANAER_RS03975	COG0784	Response regulator, receiver
AANAER_RS03980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AANAER_RS04005	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AANAER_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
AANAER_RS04045	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AANAER_RS04050	COG0735	belongs to the Fur family
AANAER_RS04060	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AANAER_RS04065	COG0840	transmembrane signaling receptor activity
AANAER_RS04070	COG0492	ferredoxin-NADP+ reductase activity
AANAER_RS04080	COG0626	cystathionine gamma-synthase activity
AANAER_RS04085	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AANAER_RS04090	COG1858	cytochrome C peroxidase
AANAER_RS04105	COG0432	Pfam Uncharacterised protein family UPF0047
AANAER_RS04115	COG2169	Transcriptional regulator
AANAER_RS04115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AANAER_RS04125	COG2151	metal-sulfur cluster biosynthetic enzyme
AANAER_RS04130	COG2166	iron-sulfur cluster assembly
AANAER_RS04135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AANAER_RS04145	COG0396	ATPase activity
AANAER_RS04150	COG0719	Fe-S assembly protein
AANAER_RS04155	COG0765	amino acid transport
AANAER_RS04160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AANAER_RS04170	COG2906	2 iron, 2 sulfur cluster binding
AANAER_RS04170	COG0822	iron-sulfur transferase activity
AANAER_RS04170	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AANAER_RS04180	COG0165	Argininosuccinate lyase
AANAER_RS04185	COG0835	chemotaxis
AANAER_RS04185	COG0784	Response regulator, receiver
AANAER_RS04190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AANAER_RS04195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AANAER_RS04200	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AANAER_RS04215	COG2326	polyphosphate kinase activity
AANAER_RS04220	COG0556	nucleotide-excision repair
AANAER_RS04230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AANAER_RS04240	COG2200	EAL domain
AANAER_RS04240	COG3287	FIST C domain
AANAER_RS04240	COG2199	diguanylate cyclase activity
AANAER_RS04295	COG0698	ribose 5-phosphate isomerase
AANAER_RS04300	COG0681	Belongs to the peptidase S26 family
AANAER_RS04305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AANAER_RS04315	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AANAER_RS04320	COG0193	aminoacyl-tRNA hydrolase activity
AANAER_RS04335	COG0860	N-Acetylmuramoyl-L-alanine amidase
AANAER_RS04345	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AANAER_RS04355	COG1758	RNA polymerase activity
AANAER_RS04360	COG0528	UMP kinase activity
AANAER_RS04370	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AANAER_RS04375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AANAER_RS04380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AANAER_RS04390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AANAER_RS04395	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AANAER_RS04405	COG4191	Histidine kinase
AANAER_RS04410	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AANAER_RS04415	COG0305	Participates in initiation and elongation during chromosome replication
AANAER_RS04430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AANAER_RS04435	COG0133	tryptophan synthase activity
AANAER_RS04445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AANAER_RS04450	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AANAER_RS04450	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AANAER_RS04475	COG3123	guanosine phosphorylase activity
AANAER_RS04505	COG0585	pseudouridine synthase activity
AANAER_RS04515	COG0840	transmembrane signaling receptor activity
AANAER_RS04520	COG0632	four-way junction helicase activity
AANAER_RS04525	COG1181	Belongs to the D-alanine--D-alanine ligase family
AANAER_RS04535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AANAER_RS04565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AANAER_RS04575	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
AANAER_RS04595	COG0051	transcription antitermination factor activity, RNA binding
AANAER_RS04600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AANAER_RS04605	COG0088	Forms part of the polypeptide exit tunnel
AANAER_RS04610	COG0089	rRNA binding
AANAER_RS04615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AANAER_RS04620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AANAER_RS04625	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AANAER_RS04630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AANAER_RS04635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AANAER_RS04640	COG0255	Belongs to the universal ribosomal protein uL29 family
AANAER_RS04645	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AANAER_RS04650	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AANAER_RS04655	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AANAER_RS04660	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AANAER_RS04665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AANAER_RS04670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AANAER_RS04675	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AANAER_RS04680	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AANAER_RS04685	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AANAER_RS04690	COG0200	Binds to the 23S rRNA
AANAER_RS04695	COG0201	protein transport
AANAER_RS04700	COG0024	Methionine aminopeptidase
AANAER_RS04705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AANAER_RS04730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AANAER_RS04745	COG1032	radical SAM domain protein
AANAER_RS04750	COG1331	Highly conserved protein containing a thioredoxin domain
AANAER_RS04760	COG0563	adenylate kinase activity
AANAER_RS04780	COG2239	Acts as a magnesium transporter
AANAER_RS04790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AANAER_RS04795	COG0322	excinuclease ABC activity
AANAER_RS04805	COG5002	protein histidine kinase activity
AANAER_RS04830	COG3437	response regulator, receiver
AANAER_RS04830	COG0784	Response regulator, receiver
AANAER_RS04835	COG3328	transposase activity
AANAER_RS04865	COG1846	Transcriptional regulator
AANAER_RS04870	COG1538	Outer membrane efflux protein
AANAER_RS04890	COG0583	DNA-binding transcription factor activity
AANAER_RS04905	COG2357	RelA SpoT domain protein
AANAER_RS04910	COG0326	Molecular chaperone. Has ATPase activity
AANAER_RS04920	COG0386	Belongs to the glutathione peroxidase family
AANAER_RS05000	COG0515	serine threonine protein kinase
AANAER_RS05070	COG3179	chitinase
AANAER_RS05100	COG3328	transposase activity
AANAER_RS05110	COG0739	heme binding
AANAER_RS05130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AANAER_RS05140	COG0484	heat shock protein binding
AANAER_RS05155	COG0484	heat shock protein binding
AANAER_RS05175	COG1858	cytochrome C peroxidase
AANAER_RS05180	COG0840	transmembrane signaling receptor activity
AANAER_RS05185	COG0708	Exodeoxyribonuclease III
AANAER_RS05210	COG2205	protein histidine kinase activity
AANAER_RS05210	COG0784	Response regulator, receiver
AANAER_RS05215	COG0583	DNA-binding transcription factor activity
AANAER_RS05235	COG0842	Transport permease protein
AANAER_RS05240	COG0842	Transport permease protein
AANAER_RS05245	COG1131	(ABC) transporter
AANAER_RS05250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AANAER_RS05260	COG1227	inorganic diphosphatase activity
AANAER_RS05265	COG0519	Catalyzes the synthesis of GMP from XMP
AANAER_RS05270	COG5002	protein histidine kinase activity
AANAER_RS05270	COG5001	Diguanylate cyclase
AANAER_RS05315	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AANAER_RS05320	COG4335	DNA alkylation repair
AANAER_RS05330	COG2902	Dehydrogenase
AANAER_RS05340	COG0189	ligase activity
AANAER_RS05340	COG4067	protein conserved in archaea
AANAER_RS05360	COG3706	GGDEF domain
AANAER_RS05360	COG5001	Diguanylate cyclase
AANAER_RS05360	COG2203	Gaf domain
AANAER_RS05360	COG4251	negative regulation of phosphorylation
AANAER_RS05375	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AANAER_RS05385	COG1984	allophanate hydrolase subunit 2
AANAER_RS05395	COG2200	EAL domain
AANAER_RS05395	COG2199	diguanylate cyclase activity
AANAER_RS05395	COG3287	FIST C domain
AANAER_RS05405	COG0513	Belongs to the DEAD box helicase family
AANAER_RS05410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AANAER_RS05420	COG1078	dGTPase activity
AANAER_RS05425	COG1702	phosphate starvation-inducible protein PhoH
AANAER_RS05435	COG2951	lytic endotransglycosylase activity
AANAER_RS05440	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AANAER_RS05445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AANAER_RS05470	COG0436	Aminotransferase
AANAER_RS05475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AANAER_RS05510	COG0217	transcriptional regulatory protein
AANAER_RS05520	COG0697	spore germination
AANAER_RS05530	COG1049	propionate catabolic process, 2-methylcitrate cycle
AANAER_RS05550	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AANAER_RS05555	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AANAER_RS05575	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AANAER_RS05580	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AANAER_RS05585	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AANAER_RS05590	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AANAER_RS05605	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AANAER_RS05610	COG0733	neurotransmitter:sodium symporter activity
AANAER_RS05615	COG2814	Major facilitator Superfamily
AANAER_RS05625	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AANAER_RS05630	COG0298	carbon dioxide binding
AANAER_RS05635	COG0409	Hydrogenase expression formation protein
AANAER_RS05645	COG0309	Hydrogenase expression formation protein (HypE)
AANAER_RS05650	COG0375	protein maturation
AANAER_RS05675	COG0410	ABC transporter
AANAER_RS05700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AANAER_RS05705	COG2171	N-acyltransferase activity
AANAER_RS05710	COG3706	GGDEF domain
AANAER_RS05725	COG2884	Cell division ATP-binding protein ftsE
AANAER_RS05730	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AANAER_RS05735	COG3103	Sh3 type 3 domain protein
AANAER_RS05735	COG0366	Alpha amylase catalytic
AANAER_RS05740	COG0564	pseudouridine synthase activity
AANAER_RS05745	COG0772	Belongs to the SEDS family
AANAER_RS05750	COG0010	Belongs to the arginase family
AANAER_RS05775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AANAER_RS05780	COG3123	guanosine phosphorylase activity
AANAER_RS05800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AANAER_RS05805	COG0066	3-isopropylmalate dehydratase activity
AANAER_RS05810	COG0473	3-isopropylmalate dehydrogenase activity
AANAER_RS05820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AANAER_RS05825	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AANAER_RS05830	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AANAER_RS05835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AANAER_RS05840	COG0202	RNA polymerase activity
AANAER_RS05845	COG0203	ribosomal protein L17
AANAER_RS05850	COG0154	amidase activity
AANAER_RS05855	COG0517	IMP dehydrogenase activity
AANAER_RS05855	COG0516	GMP reductase activity
AANAER_RS05915	COG1280	lysine exporter protein (LysE YggA)
AANAER_RS05950	COG0210	DNA helicase
AANAER_RS05955	COG2814	Major facilitator Superfamily
AANAER_RS05960	COG1566	PFAM secretion protein HlyD family protein
AANAER_RS05965	COG1309	transcriptional regulator
AANAER_RS05975	COG0662	Cupin 2, conserved barrel domain protein
AANAER_RS05980	COG0716	FMN binding
AANAER_RS06005	COG0745	RESPONSE REGULATOR receiver
AANAER_RS06010	COG1047	Peptidyl-prolyl cis-trans
AANAER_RS06015	COG1047	Peptidyl-prolyl cis-trans
AANAER_RS06040	COG1280	lysine exporter protein (LysE YggA)
AANAER_RS06045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AANAER_RS06055	COG2873	o-acetylhomoserine
AANAER_RS06060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AANAER_RS06070	COG2003	Belongs to the UPF0758 family
AANAER_RS06110	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AANAER_RS06115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AANAER_RS06120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AANAER_RS06180	COG2909	trisaccharide binding
AANAER_RS06245	COG0784	Response regulator, receiver
AANAER_RS06255	COG0039	L-malate dehydrogenase activity
AANAER_RS06260	COG0543	2 iron, 2 sulfur cluster binding
AANAER_RS06260	COG0633	Ferredoxin
AANAER_RS06285	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AANAER_RS06305	COG2267	carboxylic ester hydrolase activity
AANAER_RS06320	COG1605	Chorismate mutase
AANAER_RS06320	COG0077	Prephenate dehydratase
AANAER_RS06325	COG1368	sulfuric ester hydrolase activity
AANAER_RS06355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AANAER_RS06360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AANAER_RS06370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AANAER_RS06385	COG0521	Mo-molybdopterin cofactor biosynthetic process
AANAER_RS06390	COG0471	metal ion transport
AANAER_RS06395	COG2207	Transcriptional regulator
AANAER_RS06405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AANAER_RS06410	COG0840	transmembrane signaling receptor activity
AANAER_RS06415	COG0840	transmembrane signaling receptor activity
AANAER_RS06420	COG1193	negative regulation of DNA recombination
AANAER_RS06440	COG0583	DNA-binding transcription factor activity
AANAER_RS06445	COG2855	membrane
AANAER_RS06450	COG0730	response to heat
AANAER_RS06455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AANAER_RS06470	COG0745	RESPONSE REGULATOR receiver
AANAER_RS06485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AANAER_RS06505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AANAER_RS06515	COG2329	Antibiotic biosynthesis monooxygenase
AANAER_RS06545	COG0450	alkyl hydroperoxide reductase
AANAER_RS06565	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AANAER_RS06575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AANAER_RS06585	COG2258	MOSC domain
AANAER_RS06590	COG1881	PFAM PEBP family protein
AANAER_RS06615	COG2824	Alkylphosphonate utilization operon protein PhnA
AANAER_RS06620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AANAER_RS06625	COG0840	transmembrane signaling receptor activity
AANAER_RS06650	COG1733	regulation of RNA biosynthetic process
AANAER_RS06660	COG2249	NAD(P)H dehydrogenase (quinone) activity
AANAER_RS06665	COG0778	Nitroreductase
AANAER_RS06685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AANAER_RS06685	COG0301	tRNA thio-modification
AANAER_RS06695	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AANAER_RS06695	COG2885	chlorophyll binding
AANAER_RS06705	COG3040	lipid binding
AANAER_RS06710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AANAER_RS06715	COG0259	pyridoxamine-phosphate oxidase activity
AANAER_RS06730	COG0352	thiamine-phosphate diphosphorylase activity
AANAER_RS06735	COG0351	phosphomethylpyrimidine kinase
AANAER_RS06745	COG0488	(ABC) transporter
AANAER_RS06750	COG1607	acyl-coa hydrolase
AANAER_RS06755	COG3437	response regulator, receiver
AANAER_RS06760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AANAER_RS06765	COG2226	methyltransferase
AANAER_RS06765	COG1073	alpha beta
AANAER_RS06775	COG3001	Fructosamine kinase
AANAER_RS06780	COG0840	transmembrane signaling receptor activity
AANAER_RS06790	COG1271	oxidase subunit
AANAER_RS06805	COG0114	fumarate hydratase activity
AANAER_RS06820	COG2195	Cleaves the N-terminal amino acid of tripeptides
AANAER_RS06825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AANAER_RS06830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AANAER_RS06835	COG0569	domain protein
AANAER_RS06865	COG2030	dehydratase
AANAER_RS06880	COG1414	Transcriptional regulator
AANAER_RS06885	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AANAER_RS06890	COG0095	Lipoate-protein ligase
AANAER_RS06895	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AANAER_RS06900	COG0508	dehydrogenase complex catalyzes the overall conversion of
AANAER_RS06905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AANAER_RS06930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AANAER_RS06935	COG0745	RESPONSE REGULATOR receiver
AANAER_RS06950	COG0488	(ABC) transporter
AANAER_RS06960	COG3706	GGDEF domain
AANAER_RS06970	COG0745	RESPONSE REGULATOR receiver
AANAER_RS06975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AANAER_RS06975	COG1333	cytochrome c biogenesis protein
AANAER_RS06980	COG0500	methyltransferase
AANAER_RS06985	COG2199	diguanylate cyclase activity
AANAER_RS06985	COG2203	Gaf domain
AANAER_RS06990	COG5001	Diguanylate cyclase
AANAER_RS06990	COG4251	negative regulation of phosphorylation
AANAER_RS06990	COG3706	GGDEF domain
AANAER_RS06990	COG2203	Gaf domain
AANAER_RS06995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AANAER_RS07000	COG2833	Protein of unknown function (DUF455)
AANAER_RS07005	COG2188	Transcriptional regulator
AANAER_RS07010	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AANAER_RS07020	COG3639	organic phosphonate transmembrane transporter activity
AANAER_RS07040	COG3627	carbon phosphorus lyase activity
AANAER_RS07045	COG4107	phosphonate C-P lyase system protein PhnK
AANAER_RS07050	COG4778	phosphonate C-P lyase system protein PhnL
AANAER_RS07055	COG3454	Phosphonate metabolism
AANAER_RS07065	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AANAER_RS07070	COG1234	tRNA 3'-trailer cleavage
AANAER_RS07075	COG0133	tryptophan synthase activity
AANAER_RS07080	COG0484	heat shock protein binding
AANAER_RS07110	COG3706	GGDEF domain
AANAER_RS07115	COG2199	diguanylate cyclase activity
AANAER_RS07115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AANAER_RS07130	COG0745	RESPONSE REGULATOR receiver
AANAER_RS07135	COG4565	transcriptional regulatory protein
AANAER_RS07145	COG0137	argininosuccinate synthase activity
AANAER_RS07155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AANAER_RS07160	COG0802	atpase or kinase
AANAER_RS07165	COG1137	ATPase activity
AANAER_RS07170	COG0745	RESPONSE REGULATOR receiver
AANAER_RS07175	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AANAER_RS07185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AANAER_RS07185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AANAER_RS07210	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AANAER_RS07215	COG0247	lactate metabolic process
AANAER_RS07215	COG2181	nitrate reductase activity
AANAER_RS07220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AANAER_RS07225	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AANAER_RS07255	COG1053	succinate dehydrogenase
AANAER_RS07260	COG0745	RESPONSE REGULATOR receiver
AANAER_RS07275	COG0113	porphobilinogen synthase activity
AANAER_RS07280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AANAER_RS07285	COG0357	Ribosomal RNA small subunit methyltransferase G
AANAER_RS07360	COG0358	DNA primase activity
AANAER_RS07455	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AANAER_RS07470	COG0629	single-stranded DNA binding
AANAER_RS07665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AANAER_RS07670	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AANAER_RS07675	COG5016	pyruvate
AANAER_RS07675	COG0511	ligase activity, forming carbon-carbon bonds
AANAER_RS07680	COG3630	sodium ion export across plasma membrane
AANAER_RS07695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AANAER_RS07695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AANAER_RS07705	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AANAER_RS07730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AANAER_RS07735	COG0612	Peptidase, M16
AANAER_RS07740	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AANAER_RS07745	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AANAER_RS07750	COG0287	Prephenate dehydrogenase
AANAER_RS07755	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AANAER_RS07770	COG0527	aspartate kinase activity
AANAER_RS07775	COG0494	nUDIX hydrolase
AANAER_RS07780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AANAER_RS07785	COG2890	protein-(glutamine-N5) methyltransferase activity
AANAER_RS07790	COG0339	signal peptide processing
AANAER_RS07815	COG0071	Belongs to the small heat shock protein (HSP20) family
AANAER_RS07820	COG0071	Belongs to the small heat shock protein (HSP20) family
AANAER_RS07830	COG0582	viral genome integration into host DNA
AANAER_RS07835	COG2201	protein-glutamate methylesterase activity
AANAER_RS07840	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AANAER_RS07845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AANAER_RS07850	COG2198	Histidine kinase
AANAER_RS07850	COG0643	Histidine kinase
AANAER_RS07860	COG1185	polyribonucleotide nucleotidyltransferase activity
AANAER_RS07870	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AANAER_RS07890	COG1160	GTP binding
AANAER_RS07905	COG1749	Flagellar hook protein flgE
AANAER_RS07910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AANAER_RS07915	COG1749	Flagellar hook protein flgE
AANAER_RS07925	COG0642	Histidine kinase
AANAER_RS07930	COG0745	RESPONSE REGULATOR receiver
AANAER_RS07935	COG1674	ftsk spoiiie
AANAER_RS07935	COG1196	nuclear chromosome segregation
AANAER_RS07940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AANAER_RS07945	COG0440	acetolactate synthase activity
AANAER_RS07950	COG0028	Belongs to the TPP enzyme family
AANAER_RS07970	COG3706	GGDEF domain
AANAER_RS07975	COG0659	secondary active sulfate transmembrane transporter activity
AANAER_RS08005	COG0037	tRNA processing
AANAER_RS08030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AANAER_RS08035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AANAER_RS08040	COG3938	Belongs to the proline racemase family
AANAER_RS08045	COG2423	ornithine cyclodeaminase activity
AANAER_RS08055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AANAER_RS08075	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AANAER_RS08145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AANAER_RS08150	COG0303	'Molybdopterin
AANAER_RS08155	COG1322	Protein conserved in bacteria
AANAER_RS08160	COG0501	Belongs to the peptidase M48B family
AANAER_RS08165	COG3706	GGDEF domain
AANAER_RS08170	COG0824	Thioesterase
AANAER_RS08180	COG4191	Histidine kinase
AANAER_RS08185	COG2267	carboxylic ester hydrolase activity
AANAER_RS08190	COG0840	transmembrane signaling receptor activity
AANAER_RS08200	COG0745	RESPONSE REGULATOR receiver
AANAER_RS08205	COG0667	Aldo Keto reductase
AANAER_RS08230	COG1492	cobalamin metabolic process
AANAER_RS08240	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AANAER_RS08260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AANAER_RS08275	COG4771	TonB-dependent receptor
AANAER_RS08310	COG5002	protein histidine kinase activity
AANAER_RS08330	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AANAER_RS08335	COG0788	formyltetrahydrofolate deformylase activity
AANAER_RS08340	COG0281	malic enzyme
AANAER_RS08340	COG0280	phosphate acetyltransferase
AANAER_RS08350	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AANAER_RS08370	COG3645	SOS response
AANAER_RS08395	COG0419	ATPase involved in DNA repair
AANAER_RS08410	COG0754	glutathionylspermidine amidase activity
AANAER_RS08415	COG1663	tetraacyldisaccharide 4'-kinase activity
AANAER_RS08420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AANAER_RS08435	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AANAER_RS08445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AANAER_RS08450	COG0805	protein transport
AANAER_RS08455	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AANAER_RS08465	COG0733	neurotransmitter:sodium symporter activity
AANAER_RS08470	COG0513	Belongs to the DEAD box helicase family
AANAER_RS08495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AANAER_RS08525	COG0275	rRNA processing
AANAER_RS08535	COG0776	regulation of translation
AANAER_RS08550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AANAER_RS08570	COG0642	Histidine kinase
AANAER_RS08575	COG0745	RESPONSE REGULATOR receiver
AANAER_RS08590	COG1132	(ABC) transporter
AANAER_RS08620	COG0653	protein targeting
AANAER_RS08645	COG0039	L-malate dehydrogenase activity
AANAER_RS08655	COG2217	Heavy metal translocating P-type atpase
AANAER_RS08670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AANAER_RS08685	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AANAER_RS08685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AANAER_RS08695	COG0484	heat shock protein binding
AANAER_RS08700	COG0789	Transcriptional regulator
AANAER_RS08705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AANAER_RS08710	COG0849	cell division
AANAER_RS08720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AANAER_RS08730	COG1393	Belongs to the ArsC family
AANAER_RS08745	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AANAER_RS08750	COG0768	penicillin binding
AANAER_RS08755	COG1338	Plays a role in the flagellum-specific transport system
AANAER_RS08760	COG4251	negative regulation of phosphorylation
AANAER_RS08760	COG3706	GGDEF domain
AANAER_RS08760	COG2203	Gaf domain
AANAER_RS08760	COG5001	Diguanylate cyclase
AANAER_RS08770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AANAER_RS08780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AANAER_RS08785	COG0456	acetyltransferase
AANAER_RS08790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AANAER_RS08805	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AANAER_RS08810	COG0131	Imidazoleglycerol-phosphate dehydratase
AANAER_RS08815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AANAER_RS08820	COG1388	LysM domain
AANAER_RS08820	COG0791	NLP P60 protein
AANAER_RS08825	COG0084	hydrolase, TatD family'
AANAER_RS08835	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AANAER_RS08840	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AANAER_RS08845	COG0359	binds to the 23S rRNA
AANAER_RS08865	COG0163	prenyltransferase activity
AANAER_RS08870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AANAER_RS08875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AANAER_RS08880	COG0124	histidyl-tRNA synthetase
AANAER_RS08885	COG1166	arginine decarboxylase activity
AANAER_RS08890	COG1045	serine acetyltransferase
AANAER_RS08905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AANAER_RS08920	COG1253	flavin adenine dinucleotide binding
AANAER_RS08925	COG0748	coenzyme F420 binding
AANAER_RS08935	COG0745	RESPONSE REGULATOR receiver
AANAER_RS08945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AANAER_RS08950	COG1917	Cupin 2, conserved barrel domain protein
AANAER_RS08965	COG0527	aspartate kinase activity
AANAER_RS08990	COG2223	nitrite transmembrane transporter activity
AANAER_RS08995	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AANAER_RS09005	COG0243	molybdopterin cofactor binding
AANAER_RS09015	COG0642	Histidine kinase
AANAER_RS09025	COG0745	RESPONSE REGULATOR receiver
AANAER_RS09030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AANAER_RS09095	COG1280	lysine exporter protein (LysE YggA)
AANAER_RS09155	COG0384	phenazine biosynthesis protein PhzF
AANAER_RS09175	COG1752	Esterase of the alpha-beta hydrolase superfamily
AANAER_RS09200	COG2267	carboxylic ester hydrolase activity
AANAER_RS09210	COG1643	Atp-dependent helicase
AANAER_RS09235	COG1187	pseudouridine synthase activity
AANAER_RS09280	COG0519	Catalyzes the synthesis of GMP from XMP
AANAER_RS09280	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AANAER_RS09290	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AANAER_RS09320	COG0488	(ABC) transporter
AANAER_RS09325	COG1610	YqeY-like protein
AANAER_RS09335	COG1472	Belongs to the glycosyl hydrolase 3 family
AANAER_RS09340	COG1979	alcohol dehydrogenase
AANAER_RS09345	COG1917	Cupin 2, conserved barrel domain protein
AANAER_RS09345	COG2207	Transcriptional regulator
AANAER_RS09350	COG4191	Histidine kinase
AANAER_RS09390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AANAER_RS09400	COG2095	MarC family integral membrane protein
AANAER_RS09415	COG0300	oxidoreductase activity
AANAER_RS09420	COG1757	Na H antiporter
AANAER_RS09425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AANAER_RS09430	COG0742	ribosomal rna small subunit methyltransferase
AANAER_RS09450	COG1418	mRNA catabolic process
AANAER_RS09460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AANAER_RS09465	COG0552	protein localization to endoplasmic reticulum
AANAER_RS09480	COG5002	protein histidine kinase activity
AANAER_RS09485	COG3258	Cytochrome c
AANAER_RS09490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AANAER_RS09495	COG3150	esterase
AANAER_RS09515	COG1278	Cold shock
AANAER_RS09525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AANAER_RS09530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AANAER_RS09545	COG1592	Rubrerythrin
AANAER_RS09555	COG0728	peptidoglycan biosynthetic process
AANAER_RS09560	COG1132	(ABC) transporter
AANAER_RS09565	COG0167	dihydroorotate dehydrogenase activity
AANAER_RS09580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AANAER_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
AANAER_RS09590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AANAER_RS09595	COG0750	zinc metalloprotease
AANAER_RS09600	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AANAER_RS09615	COG0134	indole-3-glycerol-phosphate synthase activity
AANAER_RS09625	COG0727	PFAM Uncharacterised protein family (UPF0153)
AANAER_RS09630	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AANAER_RS09640	COG0674	pyruvate-flavodoxin oxidoreductase activity
AANAER_RS09640	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AANAER_RS09645	COG0028	Belongs to the TPP enzyme family
AANAER_RS09655	COG4191	Histidine kinase
AANAER_RS09660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AANAER_RS09665	COG2176	DNA-directed DNA polymerase activity
AANAER_RS09670	COG0135	phosphoribosylanthranilate isomerase activity
AANAER_RS09675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AANAER_RS09685	COG0494	nUDIX hydrolase
AANAER_RS09695	COG0642	Histidine kinase
AANAER_RS09700	COG0745	RESPONSE REGULATOR receiver
AANAER_RS09710	COG1666	GTP binding
AANAER_RS09720	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AANAER_RS09735	COG2363	Small membrane protein
AANAER_RS09745	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AANAER_RS09750	COG2252	PERMEase
AANAER_RS09760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AANAER_RS09765	COG1609	Transcriptional regulator
AANAER_RS09765	COG2207	Transcriptional regulator
AANAER_RS09775	COG0840	transmembrane signaling receptor activity
AANAER_RS09780	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AANAER_RS09785	COG0500	methyltransferase
AANAER_RS09795	COG0437	4 iron, 4 sulfur cluster binding
AANAER_RS09800	COG0243	molybdopterin cofactor binding
AANAER_RS09800	COG3383	formate dehydrogenase (NAD+) activity
AANAER_RS09830	COG4565	transcriptional regulatory protein
AANAER_RS09880	COG0439	Biotin carboxylase
AANAER_RS09915	COG0514	ATP-dependent DNA helicase (RecQ)
AANAER_RS09925	COG0450	alkyl hydroperoxide reductase
AANAER_RS09950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AANAER_RS09980	COG0628	permease
AANAER_RS09985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AANAER_RS09990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AANAER_RS10005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AANAER_RS10015	COG0745	RESPONSE REGULATOR receiver
AANAER_RS10045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AANAER_RS10085	COG0731	radical SAM domain protein
AANAER_RS10090	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AANAER_RS10100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AANAER_RS10115	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AANAER_RS10120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AANAER_RS10125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AANAER_RS10130	COG1793	dna ligase
AANAER_RS10140	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AANAER_RS10145	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AANAER_RS10145	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AANAER_RS10150	COG2026	Addiction module toxin, RelE StbE family
AANAER_RS10165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AANAER_RS10170	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AANAER_RS10185	COG0438	transferase activity, transferring glycosyl groups
AANAER_RS10215	COG0656	L-ascorbic acid biosynthetic process
AANAER_RS10225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AANAER_RS10230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AANAER_RS10250	COG0859	PFAM glycosyl transferase family 9
AANAER_RS10280	COG1696	Membrane protein involved in D-alanine export
AANAER_RS10300	COG0297	glycogen (starch) synthase activity
AANAER_RS10305	COG0463	Glycosyl transferase, family 2
AANAER_RS10310	COG0438	transferase activity, transferring glycosyl groups
AANAER_RS10320	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AANAER_RS10345	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AANAER_RS10355	COG0859	PFAM glycosyl transferase family 9
AANAER_RS10370	COG0493	'glutamate synthase
AANAER_RS10375	COG0070	glutamate synthase
AANAER_RS10375	COG0069	glutamate synthase activity
AANAER_RS10375	COG0067	glutamate synthase
AANAER_RS10400	COG1971	Probably functions as a manganese efflux pump
AANAER_RS10405	COG0428	transporter
AANAER_RS10425	COG3437	response regulator, receiver
AANAER_RS10425	COG0784	Response regulator, receiver
AANAER_RS10435	COG0745	RESPONSE REGULATOR receiver
AANAER_RS10440	COG0840	transmembrane signaling receptor activity
AANAER_RS10450	COG2204	response regulator
AANAER_RS10510	COG0410	ABC transporter
AANAER_RS10515	COG1012	belongs to the aldehyde dehydrogenase family
AANAER_RS10530	COG3287	FIST C domain
AANAER_RS10530	COG2200	EAL domain
AANAER_RS10530	COG2199	diguanylate cyclase activity
AANAER_RS10535	COG2205	protein histidine kinase activity
AANAER_RS10540	COG3706	GGDEF domain
AANAER_RS10565	COG2207	Transcriptional regulator
AANAER_RS10570	COG1846	Transcriptional regulator
AANAER_RS10585	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AANAER_RS10595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AANAER_RS10600	COG0673	inositol 2-dehydrogenase activity
AANAER_RS10620	COG1064	alcohol dehydrogenase
AANAER_RS10630	COG1979	alcohol dehydrogenase
AANAER_RS10675	COG0284	orotidine-5'-phosphate decarboxylase activity
AANAER_RS10680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AANAER_RS10685	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AANAER_RS10710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AANAER_RS10730	COG1739	Uncharacterized protein family UPF0029
AANAER_RS10740	COG0196	riboflavin kinase activity
AANAER_RS10745	COG2226	methyltransferase
AANAER_RS10750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AANAER_RS10760	COG0277	FAD linked oxidase domain protein
AANAER_RS10785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AANAER_RS10790	COG0243	molybdopterin cofactor binding
AANAER_RS10795	COG0437	4 iron, 4 sulfur cluster binding
AANAER_RS10800	COG0348	domain, Protein
AANAER_RS10805	COG3043	anaerobic respiration
AANAER_RS10810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS10830	COG0840	transmembrane signaling receptor activity
AANAER_RS10905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AANAER_RS10905	COG2010	Cytochrome c
AANAER_RS10920	COG0778	Nitroreductase
AANAER_RS10925	COG1012	belongs to the aldehyde dehydrogenase family
AANAER_RS10930	COG0386	Belongs to the glutathione peroxidase family
AANAER_RS10940	COG0778	Nitroreductase
AANAER_RS10950	COG2249	NAD(P)H dehydrogenase (quinone) activity
AANAER_RS10955	COG1979	alcohol dehydrogenase
AANAER_RS10960	COG1733	regulation of RNA biosynthetic process
AANAER_RS10965	COG2814	Major facilitator Superfamily
AANAER_RS10970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AANAER_RS10975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AANAER_RS10980	COG1047	Peptidyl-prolyl cis-trans
AANAER_RS10995	COG1090	epimerase
AANAER_RS11000	COG3279	Response regulator of the LytR AlgR family
AANAER_RS11005	COG3275	phosphorelay sensor kinase activity
AANAER_RS11015	COG0415	Belongs to the DNA photolyase family
AANAER_RS11025	COG0823	Involved in the tonB-independent uptake of proteins
AANAER_RS11035	COG0848	biopolymer transport protein
AANAER_RS11040	COG0811	peptide transport
AANAER_RS11045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AANAER_RS11050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AANAER_RS11055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AANAER_RS11060	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AANAER_RS11065	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AANAER_RS11070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AANAER_RS11080	COG1475	DNA binding
AANAER_RS11085	COG1192	Involved in chromosome partitioning
AANAER_RS11100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AANAER_RS11105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AANAER_RS11110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AANAER_RS11115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AANAER_RS11120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AANAER_RS11125	COG0251	oxidation-reduction process
AANAER_RS11130	COG0358	DNA primase activity
AANAER_RS11140	COG0328	RNA-DNA hybrid ribonuclease activity
AANAER_RS11145	COG0571	ribonuclease III activity
AANAER_RS11150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AANAER_RS11180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AANAER_RS11185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AANAER_RS11190	COG1120	ATPase activity
AANAER_RS11200	COG1629	transport
AANAER_RS11210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AANAER_RS11215	COG4604	ABC transporter, ATP-binding protein
AANAER_RS11235	COG1342	Belongs to the UPF0251 family
AANAER_RS11240	COG0501	Belongs to the peptidase M48B family
AANAER_RS11250	COG0745	RESPONSE REGULATOR receiver
AANAER_RS11255	COG0406	alpha-ribazole phosphatase activity
AANAER_RS11260	COG2062	phosphohistidine phosphatase, SixA
AANAER_RS11265	COG2081	HI0933 family
AANAER_RS11275	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AANAER_RS11285	COG0706	membrane insertase activity
AANAER_RS11290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AANAER_RS11295	COG0594	ribonuclease P activity
AANAER_RS11300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AANAER_RS11305	COG0542	response to heat
AANAER_RS11320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AANAER_RS11360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AANAER_RS11365	COG1120	ATPase activity
AANAER_RS11375	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AANAER_RS11385	COG4772	TonB-dependent receptor
AANAER_RS11400	COG2226	methyltransferase
AANAER_RS11405	COG0811	peptide transport
AANAER_RS11410	COG0848	biopolymer transport protein
AANAER_RS11420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AANAER_RS11420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AANAER_RS11425	COG0179	Fumarylacetoacetate (FAA) hydrolase
AANAER_RS11470	COG1803	Methylglyoxal synthase
AANAER_RS11485	COG0138	bifunctional purine biosynthesis protein purh
AANAER_RS11490	COG0004	ammonium transporteR
AANAER_RS11535	COG0189	ligase activity
AANAER_RS11560	COG0189	ligase activity
AANAER_RS11565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AANAER_RS11575	COG0741	lytic transglycosylase activity
AANAER_RS11575	COG0739	heme binding
AANAER_RS11575	COG1196	nuclear chromosome segregation
AANAER_RS11580	COG2239	Acts as a magnesium transporter
AANAER_RS11585	COG1280	lysine exporter protein (LysE YggA)
AANAER_RS11605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AANAER_RS11620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AANAER_RS11625	COG0606	chelatase, subunit chli
AANAER_RS11630	COG0242	peptide deformylase activity
AANAER_RS11635	COG0740	serine-type endopeptidase activity
AANAER_RS11640	COG0544	peptidyl-prolyl cis-trans isomerase activity
AANAER_RS11645	COG2304	oxidoreductase activity
AANAER_RS11650	COG2326	polyphosphate kinase activity
AANAER_RS11685	COG3328	transposase activity
AANAER_RS11700	COG0166	Belongs to the GPI family
AANAER_RS11705	COG0800	Aldolase
AANAER_RS11710	COG0129	dihydroxy-acid dehydratase activity
AANAER_RS11720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AANAER_RS11735	COG1215	transferase activity, transferring glycosyl groups
AANAER_RS11740	COG2379	hydroxypyruvate reductase
AANAER_RS11745	COG3769	mannosylglycerate metabolic process
AANAER_RS11755	COG5001	Diguanylate cyclase
AANAER_RS11755	COG3300	MHYT domain
AANAER_RS11760	COG1858	cytochrome C peroxidase
AANAER_RS11775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AANAER_RS11785	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AANAER_RS11790	COG0159	tryptophan synthase activity
AANAER_RS11795	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AANAER_RS11800	COG2255	four-way junction helicase activity
AANAER_RS11805	COG0628	permease
AANAER_RS11820	COG2995	paraquat-inducible protein a
AANAER_RS11825	COG3008	intermembrane lipid transfer
AANAER_RS11835	COG0542	response to heat
AANAER_RS11840	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AANAER_RS11845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AANAER_RS11870	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AANAER_RS11875	COG1157	protein secretion by the type III secretion system
AANAER_RS11885	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AANAER_RS11905	COG1677	Flagellar hook-basal body complex protein FliE
AANAER_RS11915	COG0455	bacterial-type flagellum organization
AANAER_RS11920	COG1419	protein localization to endoplasmic reticulum
AANAER_RS11935	COG3951	Flagellar rod assembly protein muramidase FlgJ
AANAER_RS11945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AANAER_RS11970	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AANAER_RS11980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AANAER_RS11985	COG1766	The M ring may be actively involved in energy transduction
AANAER_RS11990	COG1815	bacterial-type flagellum-dependent cell motility
AANAER_RS11995	COG4786	Flagellar basal body rod
AANAER_RS12005	COG0745	RESPONSE REGULATOR receiver
AANAER_RS12010	COG4786	Flagellar basal body rod
AANAER_RS12025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AANAER_RS12035	COG0228	four-way junction DNA binding
AANAER_RS12040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AANAER_RS12045	COG0564	pseudouridine synthase activity
AANAER_RS12050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AANAER_RS12050	COG1519	Transferase
AANAER_RS12060	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AANAER_RS12065	COG0752	glycyl-tRNA synthetase alpha subunit
AANAER_RS12075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AANAER_RS12085	COG0826	peptidase U32
AANAER_RS12090	COG0840	transmembrane signaling receptor activity
AANAER_RS12090	COG0840	transmembrane signaling receptor activity
AANAER_RS12095	COG0497	DNA recombination
AANAER_RS12100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AANAER_RS12110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AANAER_RS12115	COG0049	tRNA binding
AANAER_RS12120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AANAER_RS12140	COG1671	Belongs to the UPF0178 family
AANAER_RS12145	COG4895	conserved protein (DUF2196)
AANAER_RS12160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AANAER_RS12165	COG4139	cobalamin transport
AANAER_RS12170	COG1120	ATPase activity
AANAER_RS12185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AANAER_RS12185	COG4191	Histidine kinase
AANAER_RS12195	COG2814	Major facilitator Superfamily
AANAER_RS12210	COG1794	racemase activity, acting on amino acids and derivatives
AANAER_RS12235	COG0310	cobalt ion transport
AANAER_RS12320	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AANAER_RS12355	COG0464	growth
AANAER_RS12390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AANAER_RS12395	COG0085	RNA polymerase activity
AANAER_RS12400	COG0222	ribosome binding
AANAER_RS12405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AANAER_RS12410	COG0081	regulation of translation
AANAER_RS12415	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AANAER_RS12420	COG0250	Participates in transcription elongation, termination and antitermination
AANAER_RS12435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AANAER_RS12440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AANAER_RS12465	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AANAER_RS12470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AANAER_RS12475	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AANAER_RS12480	COG0444	Belongs to the ABC transporter superfamily
AANAER_RS12485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AANAER_RS12490	COG0174	glutamine synthetase
AANAER_RS12495	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AANAER_RS12505	COG0314	molybdopterin synthase activity
AANAER_RS12515	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AANAER_RS12520	COG1968	undecaprenyl-diphosphatase activity
AANAER_RS12530	COG0772	Belongs to the SEDS family
AANAER_RS12535	COG0768	penicillin binding
AANAER_RS12540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AANAER_RS12550	COG3706	GGDEF domain
AANAER_RS12550	COG4251	negative regulation of phosphorylation
AANAER_RS12550	COG5001	Diguanylate cyclase
AANAER_RS12550	COG2203	Gaf domain
AANAER_RS12590	COG0512	Glutamine amidotransferase of anthranilate synthase
AANAER_RS12595	COG3706	GGDEF domain
AANAER_RS12600	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AANAER_RS12605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AANAER_RS12610	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS12615	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS12620	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS12620	COG0649	NAD binding
AANAER_RS12635	COG0372	Belongs to the citrate synthase family
AANAER_RS12645	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AANAER_RS12650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS12655	COG0839	Belongs to the complex I subunit 6 family
AANAER_RS12660	COG0713	ATP synthesis coupled electron transport
AANAER_RS12665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AANAER_RS12675	COG1007	ATP synthesis coupled electron transport
AANAER_RS12685	COG1053	succinate dehydrogenase
AANAER_RS12690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AANAER_RS12695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AANAER_RS12710	COG1012	belongs to the aldehyde dehydrogenase family
AANAER_RS12745	COG2183	response to ionizing radiation
AANAER_RS12750	COG0251	oxidation-reduction process
AANAER_RS12765	COG2095	MarC family integral membrane protein
AANAER_RS12770	COG0765	amino acid transport
AANAER_RS12815	COG1280	lysine exporter protein (LysE YggA)
AANAER_RS12830	COG0372	Belongs to the citrate synthase family
AANAER_RS12840	COG2828	Protein conserved in bacteria
AANAER_RS12850	COG3706	GGDEF domain
AANAER_RS12860	COG0181	hydroxymethylbilane synthase activity
AANAER_RS12870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AANAER_RS12875	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AANAER_RS12890	COG2011	ABC-type metal ion transport system permease component
AANAER_RS12895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AANAER_RS12910	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AANAER_RS12915	COG0450	alkyl hydroperoxide reductase
AANAER_RS12925	COG0105	UTP biosynthetic process
AANAER_RS12935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AANAER_RS12940	COG0416	fatty acid biosynthetic process
AANAER_RS12945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AANAER_RS12955	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AANAER_RS12995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AANAER_RS13000	COG0540	Belongs to the ATCase OTCase family
AANAER_RS13005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AANAER_RS13020	COG2885	chlorophyll binding
AANAER_RS13035	COG1012	belongs to the aldehyde dehydrogenase family
AANAER_RS13040	COG0642	Histidine kinase
AANAER_RS13045	COG0745	RESPONSE REGULATOR receiver
AANAER_RS13055	COG3383	formate dehydrogenase (NAD+) activity
AANAER_RS13060	COG0792	nuclease activity
AANAER_RS13065	COG0038	chloride channel
AANAER_RS13075	COG0475	glutathione-regulated potassium exporter activity
AANAER_RS13075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AANAER_RS13080	COG0156	8-amino-7-oxononanoate synthase activity
AANAER_RS13090	COG0288	reversible hydration of carbon dioxide
AANAER_RS13100	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AANAER_RS13125	COG2121	Domain of unknown function (DUF374)
AANAER_RS13130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AANAER_RS13140	COG0195	Participates in both transcription termination and antitermination
AANAER_RS13145	COG0215	cysteine-tRNA ligase activity
AANAER_RS13155	COG3842	ATPase activity
AANAER_RS13160	COG1176	ABC-type spermidine putrescine transport system, permease component I
AANAER_RS13165	COG1840	ABC-type Fe3 transport system, periplasmic component
AANAER_RS13170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AANAER_RS13175	COG0629	single-stranded DNA binding
AANAER_RS13180	COG0360	Binds together with S18 to 16S ribosomal RNA
AANAER_RS13185	COG1466	dna polymerase III delta subunit
AANAER_RS13195	COG0557	exoribonuclease II activity
AANAER_RS13200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AANAER_RS13210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AANAER_RS13215	COG0758	DNA mediated transformation
AANAER_RS13220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AANAER_RS13225	COG0840	transmembrane signaling receptor activity
AANAER_RS13250	COG0343	queuine tRNA-ribosyltransferase activity
AANAER_RS13255	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AANAER_RS13260	COG1393	Belongs to the ArsC family
AANAER_RS13265	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AANAER_RS13275	COG0560	Phosphoserine phosphatase
AANAER_RS13280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AANAER_RS13285	COG0736	holo-[acyl-carrier-protein] synthase activity
AANAER_RS13290	COG0601	transmembrane transport
AANAER_RS13295	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AANAER_RS13300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AANAER_RS13320	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AANAER_RS13355	COG1706	bacterial-type flagellum-dependent cell motility
AANAER_RS13360	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AANAER_RS13375	COG0004	ammonium transporteR
AANAER_RS13380	COG0347	Belongs to the P(II) protein family
AANAER_RS13385	COG0004	ammonium transporteR
AANAER_RS13400	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AANAER_RS13405	COG2962	Rard protein
AANAER_RS13425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AANAER_RS13435	COG0640	Transcriptional regulator
AANAER_RS13440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AANAER_RS13470	COG0745	RESPONSE REGULATOR receiver
AANAER_RS13475	COG4191	Histidine kinase
AANAER_RS13515	COG3259	Nickel-dependent hydrogenase
AANAER_RS13525	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AANAER_RS13530	COG1543	Belongs to the glycosyl hydrolase 57 family
AANAER_RS13540	COG0033	Phosphoglucomutase
AANAER_RS13550	COG0297	glycogen (starch) synthase activity
AANAER_RS13565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AANAER_RS13570	COG0205	6-phosphofructokinase activity
AANAER_RS13580	COG1449	Belongs to the glycosyl hydrolase 57 family
AANAER_RS13590	COG4772	TonB-dependent receptor
AANAER_RS13600	COG4251	negative regulation of phosphorylation
AANAER_RS13610	COG0745	RESPONSE REGULATOR receiver
AANAER_RS13620	COG0745	RESPONSE REGULATOR receiver
AANAER_RS13625	COG3706	GGDEF domain
AANAER_RS13635	COG1879	ABC-type sugar transport system periplasmic component
AANAER_RS13640	COG0840	transmembrane signaling receptor activity
AANAER_RS13660	COG0129	dihydroxy-acid dehydratase activity
AANAER_RS13700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AANAER_RS13705	COG0745	RESPONSE REGULATOR receiver
AANAER_RS13710	COG0642	Histidine kinase
AANAER_RS13735	COG2095	MarC family integral membrane protein
AANAER_RS13740	COG4232	protein-disulfide reductase activity
AANAER_RS13745	COG3118	belongs to the thioredoxin family
AANAER_RS13760	COG2200	EAL domain
AANAER_RS13760	COG3287	FIST C domain
AANAER_RS13760	COG2199	diguanylate cyclase activity
AANAER_RS13765	COG0688	phosphatidylethanolamine metabolic process
AANAER_RS13790	COG0443	Heat shock 70 kDa protein
AANAER_RS13795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AANAER_RS13805	COG2358	TRAP transporter, solute receptor (TAXI family
AANAER_RS13810	COG0745	RESPONSE REGULATOR receiver
AANAER_RS13820	COG0101	tRNA pseudouridine synthase activity
AANAER_RS13830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AANAER_RS13835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AANAER_RS13845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AANAER_RS13855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AANAER_RS13860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AANAER_RS13895	COG0028	Belongs to the TPP enzyme family
AANAER_RS13920	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AANAER_RS13925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AANAER_RS13930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AANAER_RS13935	COG2226	methyltransferase
AANAER_RS13945	COG2089	acid synthase
AANAER_RS13950	COG1083	cytidylyl-transferase
AANAER_RS13955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AANAER_RS13960	COG1086	Polysaccharide biosynthesis protein
AANAER_RS13970	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AANAER_RS13975	COG0148	phosphopyruvate hydratase activity
AANAER_RS13990	COG0569	domain protein
AANAER_RS13990	COG0475	glutathione-regulated potassium exporter activity
AANAER_RS13995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AANAER_RS14010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AANAER_RS14015	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AANAER_RS14020	COG1366	Belongs to the anti-sigma-factor antagonist family
AANAER_RS14045	COG1007	ATP synthesis coupled electron transport
AANAER_RS14055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AANAER_RS14060	COG0713	ATP synthesis coupled electron transport
AANAER_RS14065	COG0839	Belongs to the complex I subunit 6 family
AANAER_RS14070	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS14075	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AANAER_RS14095	COG0649	NAD binding
AANAER_RS14100	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS14105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS14110	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AANAER_RS14115	COG1222	aaa ATPase
AANAER_RS14160	COG3328	transposase activity
AANAER_RS14165	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AANAER_RS14170	COG1252	NADH dehydrogenase
AANAER_RS14180	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AANAER_RS14185	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AANAER_RS14190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AANAER_RS14195	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AANAER_RS14200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AANAER_RS14205	COG1077	Cell shape determining protein MreB Mrl
AANAER_RS14215	COG2040	homocysteine
AANAER_RS14225	COG0445	tRNA wobble uridine modification
AANAER_RS14310	COG0745	RESPONSE REGULATOR receiver
AANAER_RS14315	COG3706	GGDEF domain
AANAER_RS14320	COG3328	transposase activity
AANAER_RS14330	COG2194	sulfuric ester hydrolase activity
AANAER_RS14340	COG0348	domain, Protein
AANAER_RS14345	COG0504	CTP synthase activity
AANAER_RS14350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AANAER_RS14350	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AANAER_RS14365	COG0693	protein deglycase activity
AANAER_RS14385	COG0587	DNA-directed DNA polymerase activity
AANAER_RS14390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AANAER_RS14415	COG0315	cyclic pyranopterin monophosphate synthase activity
AANAER_RS14420	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AANAER_RS14480	COG0670	Belongs to the BI1 family
AANAER_RS14485	COG0352	thiamine-phosphate diphosphorylase activity
AANAER_RS14490	COG4106	trans-aconitate 2-methyltransferase activity
AANAER_RS14495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AANAER_RS14500	COG0233	cytoplasmic translational termination
AANAER_RS14505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AANAER_RS14515	COG2814	Major facilitator Superfamily
AANAER_RS14525	COG3022	response to hydroperoxide
AANAER_RS14535	COG3012	SEC-C Motif Domain Protein
AANAER_RS14540	COG1555	photosystem II stabilization
AANAER_RS14555	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AANAER_RS14560	COG1704	LemA family
AANAER_RS14580	COG0546	phosphoglycolate phosphatase activity
AANAER_RS14600	COG1253	flavin adenine dinucleotide binding
AANAER_RS14620	COG2081	HI0933 family
AANAER_RS14640	COG2814	Major facilitator Superfamily
AANAER_RS14655	COG1959	2 iron, 2 sulfur cluster binding
AANAER_RS14670	COG0175	sulfate reduction
AANAER_RS14675	COG0175	sulfate reduction
AANAER_RS14680	COG2895	sulfate adenylyltransferase (ATP) activity
AANAER_RS14685	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AANAER_RS14695	COG1408	metallophosphoesterase
AANAER_RS14715	COG2308	Evidence 4 Homologs of previously reported genes of
AANAER_RS14740	COG2308	Evidence 4 Homologs of previously reported genes of
AANAER_RS14750	COG1217	gtp-binding protein TYPA
AANAER_RS14760	COG1136	(ABC) transporter
AANAER_RS14785	COG1408	metallophosphoesterase
AANAER_RS14805	COG0697	spore germination
AANAER_RS14835	COG0745	RESPONSE REGULATOR receiver
AANAER_RS14840	COG0642	Histidine kinase
AANAER_RS14845	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AANAER_RS14850	COG2860	membrane
AANAER_RS14855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AANAER_RS14860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AANAER_RS14865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AANAER_RS14875	COG0509	glycine decarboxylation via glycine cleavage system
AANAER_RS14880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AANAER_RS14885	COG0450	alkyl hydroperoxide reductase
AANAER_RS14895	COG0745	RESPONSE REGULATOR receiver
AANAER_RS14900	COG3852	Histidine kinase
AANAER_RS14905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AANAER_RS14915	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group