locus-tag	class	description
ABIV_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABIV_RS00010	COG0592	DNA-directed DNA polymerase activity
ABIV_RS00015	COG0187	DNA topoisomerase II activity
ABIV_RS00030	COG0428	transporter
ABIV_RS00035	COG2084	Dehydrogenase
ABIV_RS00040	COG1280	lysine exporter protein (LysE YggA)
ABIV_RS00065	COG0492	ferredoxin-NADP+ reductase activity
ABIV_RS00070	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABIV_RS00090	COG1238	metal cluster binding
ABIV_RS00095	COG1309	transcriptional regulator
ABIV_RS00120	COG4191	Histidine kinase
ABIV_RS00135	COG0564	pseudouridine synthase activity
ABIV_RS00140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABIV_RS00145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABIV_RS00150	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABIV_RS00170	COG0745	RESPONSE REGULATOR receiver
ABIV_RS00175	COG0642	Histidine kinase
ABIV_RS00195	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABIV_RS00200	COG0724	RNA recognition motif
ABIV_RS00205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABIV_RS00210	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABIV_RS00225	COG0107	imidazoleglycerol-phosphate synthase activity
ABIV_RS00230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABIV_RS00240	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ABIV_RS00240	COG0517	IMP dehydrogenase activity
ABIV_RS00245	COG1187	pseudouridine synthase activity
ABIV_RS00250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ABIV_RS00250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABIV_RS00255	COG1981	membrane
ABIV_RS00260	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABIV_RS00265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABIV_RS00275	COG1053	succinate dehydrogenase
ABIV_RS00285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABIV_RS00300	COG0367	asparagine synthase
ABIV_RS00310	COG0306	phosphate transporter
ABIV_RS00320	COG0513	Belongs to the DEAD box helicase family
ABIV_RS00325	COG0439	Biotin carboxylase
ABIV_RS00330	COG0511	ligase activity, forming carbon-carbon bonds
ABIV_RS00345	COG0247	lactate metabolic process
ABIV_RS00350	COG1139	Iron-sulfur cluster binding protein
ABIV_RS00355	COG1556	Lactate utilization protein
ABIV_RS00365	COG0745	RESPONSE REGULATOR receiver
ABIV_RS00370	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABIV_RS00395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABIV_RS00400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABIV_RS00405	COG0390	transport system, permease component
ABIV_RS00415	COG1733	regulation of RNA biosynthetic process
ABIV_RS00420	COG0604	alcohol dehydrogenase
ABIV_RS00425	COG1733	regulation of RNA biosynthetic process
ABIV_RS00430	COG3118	belongs to the thioredoxin family
ABIV_RS00435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABIV_RS00445	COG1280	lysine exporter protein (LysE YggA)
ABIV_RS00450	COG0348	domain, Protein
ABIV_RS00455	COG4191	Histidine kinase
ABIV_RS00460	COG0745	RESPONSE REGULATOR receiver
ABIV_RS00475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABIV_RS00490	COG0189	ligase activity
ABIV_RS00510	COG0052	Belongs to the universal ribosomal protein uS2 family
ABIV_RS00525	COG0642	Histidine kinase
ABIV_RS00530	COG0745	RESPONSE REGULATOR receiver
ABIV_RS00535	COG2353	YceI-like domain
ABIV_RS00545	COG3220	belongs to the UPF0276 family
ABIV_RS00555	COG2205	protein histidine kinase activity
ABIV_RS00555	COG0745	RESPONSE REGULATOR receiver
ABIV_RS00555	COG4191	Histidine kinase
ABIV_RS00560	COG0745	RESPONSE REGULATOR receiver
ABIV_RS00575	COG0534	Mate efflux family protein
ABIV_RS00580	COG0460	homoserine dehydrogenase
ABIV_RS00585	COG0436	Aminotransferase
ABIV_RS00595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABIV_RS00600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ABIV_RS00605	COG0254	rRNA binding
ABIV_RS00610	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABIV_RS00615	COG3153	acetyltransferase
ABIV_RS00615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABIV_RS00620	COG0109	protoheme IX farnesyltransferase activity
ABIV_RS00625	COG2199	diguanylate cyclase activity
ABIV_RS00630	COG0668	transmembrane transport
ABIV_RS00640	COG0840	transmembrane signaling receptor activity
ABIV_RS00655	COG0840	transmembrane signaling receptor activity
ABIV_RS00660	COG4191	Histidine kinase
ABIV_RS00670	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABIV_RS00680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABIV_RS00685	COG0237	dephospho-CoA kinase activity
ABIV_RS00690	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABIV_RS00695	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABIV_RS00700	COG1741	Belongs to the pirin family
ABIV_RS00710	COG2353	YceI-like domain
ABIV_RS00720	COG1280	lysine exporter protein (LysE YggA)
ABIV_RS00730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABIV_RS00735	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABIV_RS00740	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABIV_RS00750	COG0505	Belongs to the CarA family
ABIV_RS00770	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABIV_RS00770	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABIV_RS00785	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABIV_RS00790	COG0489	protein tyrosine kinase activity
ABIV_RS00795	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABIV_RS00805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABIV_RS00805	COG0140	phosphoribosyl-ATP diphosphatase activity
ABIV_RS00825	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ABIV_RS00830	COG0646	methionine synthase
ABIV_RS00830	COG1410	methionine synthase
ABIV_RS00845	COG1854	S-ribosylhomocysteine lyase activity
ABIV_RS00855	COG0546	phosphoglycolate phosphatase activity
ABIV_RS00865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABIV_RS00870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABIV_RS00875	COG2770	Histidine kinase
ABIV_RS00875	COG2205	protein histidine kinase activity
ABIV_RS00880	COG0745	RESPONSE REGULATOR receiver
ABIV_RS00890	COG0704	Plays a role in the regulation of phosphate uptake
ABIV_RS00895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABIV_RS00900	COG0581	inorganic phosphate transmembrane transporter activity
ABIV_RS00905	COG0573	inorganic phosphate transmembrane transporter activity
ABIV_RS00915	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ABIV_RS00925	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABIV_RS00930	COG0268	Binds directly to 16S ribosomal RNA
ABIV_RS00935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABIV_RS00940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABIV_RS00945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABIV_RS00950	COG0746	molybdenum cofactor guanylyltransferase activity
ABIV_RS00955	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABIV_RS00975	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABIV_RS00980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABIV_RS00985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABIV_RS00990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABIV_RS01020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABIV_RS01040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABIV_RS01055	COG1131	(ABC) transporter
ABIV_RS01085	COG1028	Short-chain dehydrogenase reductase Sdr
ABIV_RS01090	COG2986	histidine ammonia-lyase
ABIV_RS01110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABIV_RS01115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABIV_RS01130	COG0575	Belongs to the CDS family
ABIV_RS01135	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABIV_RS01155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABIV_RS01165	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABIV_RS01165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABIV_RS01170	COG1324	tolerance protein
ABIV_RS01175	COG2022	thiamine diphosphate biosynthetic process
ABIV_RS01220	COG3210	domain, Protein
ABIV_RS01220	COG3210	domain, Protein
ABIV_RS01245	COG0745	RESPONSE REGULATOR receiver
ABIV_RS01275	COG2885	chlorophyll binding
ABIV_RS01280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABIV_RS01285	COG0792	nuclease activity
ABIV_RS01295	COG0840	transmembrane signaling receptor activity
ABIV_RS01315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABIV_RS01325	COG0540	Belongs to the ATCase OTCase family
ABIV_RS01330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABIV_RS01340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABIV_RS01350	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABIV_RS01355	COG1687	branched-chain amino acid
ABIV_RS01365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABIV_RS01370	COG0416	fatty acid biosynthetic process
ABIV_RS01375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABIV_RS01385	COG0105	UTP biosynthetic process
ABIV_RS01395	COG0450	alkyl hydroperoxide reductase
ABIV_RS01400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABIV_RS01405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABIV_RS01410	COG2011	ABC-type metal ion transport system permease component
ABIV_RS01415	COG1464	Belongs to the NlpA lipoprotein family
ABIV_RS01425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABIV_RS01430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABIV_RS01445	COG0181	hydroxymethylbilane synthase activity
ABIV_RS01450	COG1335	isochorismatase
ABIV_RS01455	COG1879	ABC-type sugar transport system periplasmic component
ABIV_RS01460	COG4191	Histidine kinase
ABIV_RS01460	COG0784	Response regulator, receiver
ABIV_RS01470	COG2828	Protein conserved in bacteria
ABIV_RS01475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABIV_RS01485	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ABIV_RS01495	COG1280	lysine exporter protein (LysE YggA)
ABIV_RS01500	COG1309	transcriptional regulator
ABIV_RS01505	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ABIV_RS01510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ABIV_RS01530	COG0765	amino acid transport
ABIV_RS01535	COG2095	MarC family integral membrane protein
ABIV_RS01560	COG0251	oxidation-reduction process
ABIV_RS01570	COG2183	response to ionizing radiation
ABIV_RS01595	COG1012	belongs to the aldehyde dehydrogenase family
ABIV_RS01605	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ABIV_RS01610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ABIV_RS01615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABIV_RS01620	COG1053	succinate dehydrogenase
ABIV_RS01630	COG1007	ATP synthesis coupled electron transport
ABIV_RS01640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABIV_RS01645	COG0713	ATP synthesis coupled electron transport
ABIV_RS01650	COG0839	Belongs to the complex I subunit 6 family
ABIV_RS01655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABIV_RS01660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABIV_RS01670	COG0372	Belongs to the citrate synthase family
ABIV_RS01680	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ABIV_RS01685	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABIV_RS01685	COG0649	NAD binding
ABIV_RS01690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABIV_RS01695	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABIV_RS01700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ABIV_RS01705	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABIV_RS01715	COG0512	Glutamine amidotransferase of anthranilate synthase
ABIV_RS01755	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABIV_RS01760	COG0768	penicillin binding
ABIV_RS01765	COG0772	Belongs to the SEDS family
ABIV_RS01775	COG1968	undecaprenyl-diphosphatase activity
ABIV_RS01780	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ABIV_RS01790	COG0314	molybdopterin synthase activity
ABIV_RS01795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ABIV_RS01800	COG0174	glutamine synthetase
ABIV_RS01805	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ABIV_RS01810	COG0444	Belongs to the ABC transporter superfamily
ABIV_RS01815	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ABIV_RS01820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABIV_RS01850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABIV_RS01855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABIV_RS01870	COG0250	Participates in transcription elongation, termination and antitermination
ABIV_RS01875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABIV_RS01880	COG0081	regulation of translation
ABIV_RS01885	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABIV_RS01890	COG0222	ribosome binding
ABIV_RS01895	COG0085	RNA polymerase activity
ABIV_RS01900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABIV_RS01920	COG0582	viral genome integration into host DNA
ABIV_RS02020	COG4895	conserved protein (DUF2196)
ABIV_RS02025	COG1671	Belongs to the UPF0178 family
ABIV_RS02045	COG2010	Cytochrome c
ABIV_RS02050	COG2010	Cytochrome c
ABIV_RS02065	COG0535	radical SAM domain protein
ABIV_RS02075	COG1648	precorrin-2 dehydrogenase activity
ABIV_RS02075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABIV_RS02095	COG1522	sequence-specific DNA binding
ABIV_RS02115	COG0038	chloride channel
ABIV_RS02135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABIV_RS02140	COG0049	tRNA binding
ABIV_RS02145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABIV_RS02150	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABIV_RS02155	COG0497	DNA recombination
ABIV_RS02165	COG0840	transmembrane signaling receptor activity
ABIV_RS02165	COG0840	transmembrane signaling receptor activity
ABIV_RS02170	COG0826	peptidase U32
ABIV_RS02190	COG0752	glycyl-tRNA synthetase alpha subunit
ABIV_RS02195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABIV_RS02205	COG1519	Transferase
ABIV_RS02210	COG0564	pseudouridine synthase activity
ABIV_RS02215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABIV_RS02220	COG0228	four-way junction DNA binding
ABIV_RS02230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABIV_RS02245	COG0745	RESPONSE REGULATOR receiver
ABIV_RS02255	COG4786	Flagellar basal body rod
ABIV_RS02260	COG1815	bacterial-type flagellum-dependent cell motility
ABIV_RS02265	COG1766	The M ring may be actively involved in energy transduction
ABIV_RS02270	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABIV_RS02290	COG1749	Flagellar hook protein flgE
ABIV_RS02300	COG1749	Flagellar hook protein flgE
ABIV_RS02325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ABIV_RS02335	COG3951	Flagellar rod assembly protein muramidase FlgJ
ABIV_RS02350	COG1419	protein localization to endoplasmic reticulum
ABIV_RS02355	COG0455	bacterial-type flagellum organization
ABIV_RS02365	COG1677	Flagellar hook-basal body complex protein FliE
ABIV_RS02385	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABIV_RS02395	COG1157	protein secretion by the type III secretion system
ABIV_RS02400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABIV_RS02405	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABIV_RS02420	COG0243	molybdopterin cofactor binding
ABIV_RS02430	COG3005	denitrification pathway
ABIV_RS02435	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ABIV_RS02440	COG1333	cytochrome c biogenesis protein
ABIV_RS02440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABIV_RS02445	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ABIV_RS02455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABIV_RS02460	COG0542	response to heat
ABIV_RS02470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ABIV_RS02480	COG0628	permease
ABIV_RS02485	COG2255	four-way junction helicase activity
ABIV_RS02490	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABIV_RS02495	COG0159	tryptophan synthase activity
ABIV_RS02500	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ABIV_RS02510	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABIV_RS02530	COG1858	cytochrome C peroxidase
ABIV_RS02540	COG5001	Diguanylate cyclase
ABIV_RS02540	COG4251	negative regulation of phosphorylation
ABIV_RS02540	COG3706	GGDEF domain
ABIV_RS02540	COG2203	Gaf domain
ABIV_RS02550	COG0745	RESPONSE REGULATOR receiver
ABIV_RS02555	COG0642	Histidine kinase
ABIV_RS02560	COG2081	HI0933 family
ABIV_RS02565	COG0840	transmembrane signaling receptor activity
ABIV_RS02570	COG0745	RESPONSE REGULATOR receiver
ABIV_RS02575	COG0840	transmembrane signaling receptor activity
ABIV_RS02580	COG5000	phosphorelay sensor kinase activity
ABIV_RS02585	COG1692	metallophosphoesterase
ABIV_RS02605	COG2226	methyltransferase
ABIV_RS02610	COG1570	exodeoxyribonuclease VII activity
ABIV_RS02620	COG0840	transmembrane signaling receptor activity
ABIV_RS02630	COG0745	RESPONSE REGULATOR receiver
ABIV_RS02640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABIV_RS02650	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABIV_RS02655	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABIV_RS02665	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABIV_RS02670	COG0459	protein refolding
ABIV_RS02685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABIV_RS02690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABIV_RS02695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABIV_RS02700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABIV_RS02705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABIV_RS02715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABIV_RS02720	COG2264	protein methyltransferase activity
ABIV_RS02725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABIV_RS02735	COG0784	Response regulator, receiver
ABIV_RS02735	COG3437	response regulator, receiver
ABIV_RS02750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABIV_RS02770	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABIV_RS02780	COG1309	transcriptional regulator
ABIV_RS02790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABIV_RS02795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABIV_RS02800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABIV_RS02805	COG0640	Transcriptional regulator
ABIV_RS02810	COG2217	Heavy metal translocating P-type atpase
ABIV_RS02815	COG0481	GTPase activity
ABIV_RS02825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABIV_RS02835	COG0482	sulfurtransferase activity
ABIV_RS02840	COG0482	sulfurtransferase activity
ABIV_RS02845	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABIV_RS02850	COG0006	proline dipeptidase activity
ABIV_RS02855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABIV_RS02860	COG0402	S-adenosylhomocysteine deaminase activity
ABIV_RS02865	COG0616	signal peptide processing
ABIV_RS02870	COG0513	Belongs to the DEAD box helicase family
ABIV_RS02880	COG0280	phosphate acetyltransferase
ABIV_RS02885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABIV_RS02900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABIV_RS02920	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ABIV_RS02930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABIV_RS02940	COG0745	RESPONSE REGULATOR receiver
ABIV_RS02945	COG5002	protein histidine kinase activity
ABIV_RS02995	COG0579	oxidoreductase
ABIV_RS03000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABIV_RS03015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABIV_RS03035	COG4774	siderophore transport
ABIV_RS03065	COG0714	Associated with various cellular activities
ABIV_RS03075	COG0052	Belongs to the universal ribosomal protein uS2 family
ABIV_RS03080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABIV_RS03085	COG1136	(ABC) transporter
ABIV_RS03095	COG0194	GDP metabolic process
ABIV_RS03100	COG2199	diguanylate cyclase activity
ABIV_RS03100	COG2200	EAL domain
ABIV_RS03100	COG3287	FIST C domain
ABIV_RS03105	COG2217	Heavy metal translocating P-type atpase
ABIV_RS03140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABIV_RS03145	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABIV_RS03150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABIV_RS03170	COG2056	Na+-H+ antiporter family
ABIV_RS03175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABIV_RS03180	COG2814	Major facilitator Superfamily
ABIV_RS03200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABIV_RS03220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABIV_RS03230	COG0525	valine-tRNA ligase activity
ABIV_RS03240	COG0210	DNA helicase
ABIV_RS03255	COG0585	pseudouridine synthase activity
ABIV_RS03265	COG0840	transmembrane signaling receptor activity
ABIV_RS03270	COG0632	four-way junction helicase activity
ABIV_RS03275	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABIV_RS03285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABIV_RS03300	COG0242	peptide deformylase activity
ABIV_RS03320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABIV_RS03325	COG0784	Response regulator, receiver
ABIV_RS03325	COG2205	protein histidine kinase activity
ABIV_RS03335	COG0051	transcription antitermination factor activity, RNA binding
ABIV_RS03340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABIV_RS03345	COG0088	Forms part of the polypeptide exit tunnel
ABIV_RS03350	COG0089	rRNA binding
ABIV_RS03355	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABIV_RS03360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABIV_RS03365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABIV_RS03370	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABIV_RS03375	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABIV_RS03380	COG0255	Belongs to the universal ribosomal protein uL29 family
ABIV_RS03385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABIV_RS03390	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABIV_RS03395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABIV_RS03400	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABIV_RS03405	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABIV_RS03410	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABIV_RS03415	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABIV_RS03420	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABIV_RS03425	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABIV_RS03430	COG0200	Binds to the 23S rRNA
ABIV_RS03435	COG0201	protein transport
ABIV_RS03440	COG0024	Methionine aminopeptidase
ABIV_RS03445	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABIV_RS03450	COG3706	GGDEF domain
ABIV_RS03455	COG1573	uracil-dna glycosylase
ABIV_RS03465	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABIV_RS03480	COG1032	radical SAM domain protein
ABIV_RS03485	COG0563	adenylate kinase activity
ABIV_RS03500	COG3264	Mechanosensitive ion channel
ABIV_RS03500	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ABIV_RS03510	COG2239	Acts as a magnesium transporter
ABIV_RS03520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABIV_RS03525	COG0322	excinuclease ABC activity
ABIV_RS03545	COG0642	Histidine kinase
ABIV_RS03560	COG0386	Belongs to the glutathione peroxidase family
ABIV_RS03570	COG0484	heat shock protein binding
ABIV_RS03585	COG0484	heat shock protein binding
ABIV_RS03605	COG1858	cytochrome C peroxidase
ABIV_RS03615	COG0708	Exodeoxyribonuclease III
ABIV_RS03625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABIV_RS03645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABIV_RS03650	COG0765	amino acid transport
ABIV_RS03660	COG1380	Effector of murein hydrolase LrgA
ABIV_RS03665	COG1346	cytolysis
ABIV_RS03695	COG1942	4-Oxalocrotonate Tautomerase
ABIV_RS03705	COG1115	amino acid carrier protein
ABIV_RS03715	COG2197	response regulator
ABIV_RS03720	COG1027	Aspartate ammonia-lyase
ABIV_RS03730	COG1227	inorganic diphosphatase activity
ABIV_RS03735	COG2207	Transcriptional regulator
ABIV_RS03735	COG1917	Cupin 2, conserved barrel domain protein
ABIV_RS03740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABIV_RS03750	COG4335	DNA alkylation repair
ABIV_RS03775	COG2203	Gaf domain
ABIV_RS03775	COG4251	negative regulation of phosphorylation
ABIV_RS03775	COG5001	Diguanylate cyclase
ABIV_RS03775	COG3706	GGDEF domain
ABIV_RS03790	COG0326	Molecular chaperone. Has ATPase activity
ABIV_RS03805	COG0326	Molecular chaperone. Has ATPase activity
ABIV_RS03815	COG0583	DNA-binding transcription factor activity
ABIV_RS03840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABIV_RS03870	COG1611	Belongs to the LOG family
ABIV_RS03880	COG4753	response regulator
ABIV_RS03880	COG2207	Transcriptional regulator
ABIV_RS03885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABIV_RS03900	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ABIV_RS03910	COG1984	allophanate hydrolase subunit 2
ABIV_RS03920	COG2200	EAL domain
ABIV_RS03920	COG3287	FIST C domain
ABIV_RS03920	COG2199	diguanylate cyclase activity
ABIV_RS03930	COG0840	transmembrane signaling receptor activity
ABIV_RS03935	COG0513	Belongs to the DEAD box helicase family
ABIV_RS03955	COG0277	FAD linked oxidase domain protein
ABIV_RS03965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABIV_RS03970	COG2226	methyltransferase
ABIV_RS03975	COG0196	riboflavin kinase activity
ABIV_RS03985	COG1739	Uncharacterized protein family UPF0029
ABIV_RS04005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABIV_RS04015	COG0069	glutamate synthase activity
ABIV_RS04015	COG0069	glutamate synthase activity
ABIV_RS04030	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ABIV_RS04035	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABIV_RS04040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABIV_RS04045	COG0284	orotidine-5'-phosphate decarboxylase activity
ABIV_RS04070	COG3852	Histidine kinase
ABIV_RS04140	COG0070	glutamate synthase
ABIV_RS04140	COG0067	glutamate synthase
ABIV_RS04140	COG0069	glutamate synthase activity
ABIV_RS04145	COG0493	'glutamate synthase
ABIV_RS04150	COG0483	inositol monophosphate 1-phosphatase activity
ABIV_RS04155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABIV_RS04165	COG0859	PFAM glycosyl transferase family 9
ABIV_RS04175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ABIV_RS04200	COG0515	serine threonine protein kinase
ABIV_RS04205	COG2194	sulfuric ester hydrolase activity
ABIV_RS04215	COG0463	Glycosyl transferase, family 2
ABIV_RS04220	COG0438	transferase activity, transferring glycosyl groups
ABIV_RS04230	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABIV_RS04240	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ABIV_RS04260	COG2194	sulfuric ester hydrolase activity
ABIV_RS04270	COG0859	PFAM glycosyl transferase family 9
ABIV_RS04290	COG0859	PFAM glycosyl transferase family 9
ABIV_RS04305	COG0166	Belongs to the GPI family
ABIV_RS04315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABIV_RS04345	COG0482	sulfurtransferase activity
ABIV_RS04355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABIV_RS04360	COG0463	Glycosyl transferase, family 2
ABIV_RS04385	COG0438	transferase activity, transferring glycosyl groups
ABIV_RS04400	COG0438	transferase activity, transferring glycosyl groups
ABIV_RS04420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABIV_RS04425	COG0110	maltose O-acetyltransferase activity
ABIV_RS04430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABIV_RS04435	COG1086	Polysaccharide biosynthesis protein
ABIV_RS04445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABIV_RS04445	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ABIV_RS04450	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ABIV_RS04460	COG1793	dna ligase
ABIV_RS04475	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABIV_RS04490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABIV_RS04500	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABIV_RS04505	COG0731	radical SAM domain protein
ABIV_RS04525	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ABIV_RS04530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABIV_RS04535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABIV_RS04540	COG1595	DNA-templated transcription, initiation
ABIV_RS04550	COG0450	alkyl hydroperoxide reductase
ABIV_RS04555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABIV_RS04560	COG0840	transmembrane signaling receptor activity
ABIV_RS04565	COG2203	Gaf domain
ABIV_RS04565	COG5001	Diguanylate cyclase
ABIV_RS04565	COG4251	negative regulation of phosphorylation
ABIV_RS04565	COG3706	GGDEF domain
ABIV_RS04575	COG4191	Histidine kinase
ABIV_RS04580	COG0500	methyltransferase
ABIV_RS04605	COG2884	Cell division ATP-binding protein ftsE
ABIV_RS04610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABIV_RS04620	COG0564	pseudouridine synthase activity
ABIV_RS04625	COG0772	Belongs to the SEDS family
ABIV_RS04630	COG0010	Belongs to the arginase family
ABIV_RS04650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABIV_RS04655	COG3123	guanosine phosphorylase activity
ABIV_RS04675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABIV_RS04680	COG0066	3-isopropylmalate dehydratase activity
ABIV_RS04685	COG0473	3-isopropylmalate dehydrogenase activity
ABIV_RS04700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABIV_RS04705	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABIV_RS04710	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABIV_RS04715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABIV_RS04720	COG0202	RNA polymerase activity
ABIV_RS04725	COG0203	ribosomal protein L17
ABIV_RS04730	COG0154	amidase activity
ABIV_RS04735	COG0517	IMP dehydrogenase activity
ABIV_RS04735	COG0516	GMP reductase activity
ABIV_RS04805	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABIV_RS04815	COG3706	GGDEF domain
ABIV_RS04840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABIV_RS04845	COG1047	Peptidyl-prolyl cis-trans
ABIV_RS04855	COG0716	FMN binding
ABIV_RS04870	COG2391	methyltransferase activity
ABIV_RS04880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ABIV_RS04890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABIV_RS04900	COG2003	Belongs to the UPF0758 family
ABIV_RS04915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABIV_RS04920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABIV_RS05180	COG0457	Tetratricopeptide repeat
ABIV_RS05180	COG0859	PFAM glycosyl transferase family 9
ABIV_RS05275	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ABIV_RS05295	COG0420	3'-5' exonuclease activity
ABIV_RS05300	COG0419	ATPase involved in DNA repair
ABIV_RS05305	COG1122	ATPase activity
ABIV_RS05345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABIV_RS05365	COG4771	TonB-dependent receptor
ABIV_RS05370	COG5002	protein histidine kinase activity
ABIV_RS05380	COG4191	Histidine kinase
ABIV_RS05385	COG2199	diguanylate cyclase activity
ABIV_RS05385	COG2200	EAL domain
ABIV_RS05385	COG3287	FIST C domain
ABIV_RS05395	COG3706	GGDEF domain
ABIV_RS05405	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABIV_RS05415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABIV_RS05420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABIV_RS05430	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABIV_RS05435	COG0471	metal ion transport
ABIV_RS05440	COG0840	transmembrane signaling receptor activity
ABIV_RS05450	COG1921	L-seryl-tRNASec selenium transferase activity
ABIV_RS05455	COG0709	Synthesizes selenophosphate from selenide and ATP
ABIV_RS05460	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ABIV_RS05465	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABIV_RS05470	COG3639	organic phosphonate transmembrane transporter activity
ABIV_RS05480	COG2204	response regulator
ABIV_RS05485	COG2205	protein histidine kinase activity
ABIV_RS05515	COG0437	4 iron, 4 sulfur cluster binding
ABIV_RS05525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ABIV_RS05545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABIV_RS05550	COG0840	transmembrane signaling receptor activity
ABIV_RS05555	COG0840	transmembrane signaling receptor activity
ABIV_RS05560	COG1193	negative regulation of DNA recombination
ABIV_RS05565	COG0668	transmembrane transport
ABIV_RS05580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABIV_RS05600	COG1881	PFAM PEBP family protein
ABIV_RS05610	COG1794	racemase activity, acting on amino acids and derivatives
ABIV_RS05620	COG2824	Alkylphosphonate utilization operon protein PhnA
ABIV_RS05625	COG1742	UPF0060 membrane protein
ABIV_RS05635	COG1917	Cupin 2, conserved barrel domain protein
ABIV_RS05635	COG2207	Transcriptional regulator
ABIV_RS05650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABIV_RS05655	COG2258	MOSC domain
ABIV_RS05660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABIV_RS05700	COG1733	regulation of RNA biosynthetic process
ABIV_RS05705	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABIV_RS05715	COG0778	Nitroreductase
ABIV_RS05730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABIV_RS05730	COG0301	tRNA thio-modification
ABIV_RS05735	COG3040	lipid binding
ABIV_RS05760	COG4294	response to UV
ABIV_RS05775	COG2200	EAL domain
ABIV_RS05780	COG0259	pyridoxamine-phosphate oxidase activity
ABIV_RS05795	COG0352	thiamine-phosphate diphosphorylase activity
ABIV_RS05800	COG0351	phosphomethylpyrimidine kinase
ABIV_RS05810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABIV_RS05845	COG3287	FIST C domain
ABIV_RS05845	COG2199	diguanylate cyclase activity
ABIV_RS05845	COG2200	EAL domain
ABIV_RS05850	COG0840	transmembrane signaling receptor activity
ABIV_RS05855	COG0488	(ABC) transporter
ABIV_RS05860	COG1607	acyl-coa hydrolase
ABIV_RS05880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABIV_RS05885	COG2226	methyltransferase
ABIV_RS05930	COG0114	fumarate hydratase activity
ABIV_RS05940	COG3852	Histidine kinase
ABIV_RS05945	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABIV_RS05950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABIV_RS05970	COG2030	dehydratase
ABIV_RS05990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABIV_RS05995	COG0095	Lipoate-protein ligase
ABIV_RS06000	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ABIV_RS06005	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABIV_RS06010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABIV_RS06025	COG0488	(ABC) transporter
ABIV_RS06040	COG0681	Belongs to the peptidase S26 family
ABIV_RS06060	COG0745	RESPONSE REGULATOR receiver
ABIV_RS06100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ABIV_RS06135	COG1459	type II secretion system
ABIV_RS06145	COG2165	general secretion pathway protein
ABIV_RS06185	COG0513	Belongs to the DEAD box helicase family
ABIV_RS06190	COG0733	neurotransmitter:sodium symporter activity
ABIV_RS06200	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABIV_RS06205	COG0805	protein transport
ABIV_RS06210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABIV_RS06215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ABIV_RS06235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABIV_RS06240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABIV_RS06245	COG1663	tetraacyldisaccharide 4'-kinase activity
ABIV_RS06260	COG0754	glutathionylspermidine amidase activity
ABIV_RS06270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABIV_RS06305	COG1401	restriction endodeoxyribonuclease activity
ABIV_RS06340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABIV_RS06360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABIV_RS06370	COG0280	phosphate acetyltransferase
ABIV_RS06370	COG0281	malic enzyme
ABIV_RS06375	COG0788	formyltetrahydrofolate deformylase activity
ABIV_RS06380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ABIV_RS06395	COG0745	RESPONSE REGULATOR receiver
ABIV_RS06400	COG2770	Histidine kinase
ABIV_RS06400	COG2205	protein histidine kinase activity
ABIV_RS06410	COG0348	domain, Protein
ABIV_RS06415	COG0811	peptide transport
ABIV_RS06420	COG0848	biopolymer transport protein
ABIV_RS06440	COG0745	RESPONSE REGULATOR receiver
ABIV_RS06445	COG1333	cytochrome c biogenesis protein
ABIV_RS06445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABIV_RS06450	COG0500	methyltransferase
ABIV_RS06455	COG2199	diguanylate cyclase activity
ABIV_RS06455	COG2203	Gaf domain
ABIV_RS06460	COG2203	Gaf domain
ABIV_RS06460	COG5001	Diguanylate cyclase
ABIV_RS06460	COG3706	GGDEF domain
ABIV_RS06460	COG4251	negative regulation of phosphorylation
ABIV_RS06470	COG2833	Protein of unknown function (DUF455)
ABIV_RS06475	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ABIV_RS06485	COG0133	tryptophan synthase activity
ABIV_RS06490	COG0484	heat shock protein binding
ABIV_RS06495	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABIV_RS06515	COG2207	Transcriptional regulator
ABIV_RS06515	COG4753	response regulator
ABIV_RS06520	COG2201	protein-glutamate methylesterase activity
ABIV_RS06535	COG0137	argininosuccinate synthase activity
ABIV_RS06545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABIV_RS06550	COG0802	atpase or kinase
ABIV_RS06555	COG1137	ATPase activity
ABIV_RS06560	COG3706	GGDEF domain
ABIV_RS06565	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABIV_RS06570	COG5002	protein histidine kinase activity
ABIV_RS06575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABIV_RS06575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABIV_RS06595	COG0840	transmembrane signaling receptor activity
ABIV_RS06600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABIV_RS06605	COG0247	lactate metabolic process
ABIV_RS06605	COG2181	nitrate reductase activity
ABIV_RS06610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABIV_RS06615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABIV_RS06620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABIV_RS06625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABIV_RS06645	COG0745	RESPONSE REGULATOR receiver
ABIV_RS06655	COG0113	porphobilinogen synthase activity
ABIV_RS06660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABIV_RS06665	COG0357	Ribosomal RNA small subunit methyltransferase G
ABIV_RS06685	COG3852	Histidine kinase
ABIV_RS06720	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ABIV_RS06725	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ABIV_RS06730	COG0511	ligase activity, forming carbon-carbon bonds
ABIV_RS06730	COG5016	pyruvate
ABIV_RS06735	COG3630	sodium ion export across plasma membrane
ABIV_RS06750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABIV_RS06750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABIV_RS06760	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ABIV_RS06785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABIV_RS06790	COG0612	Peptidase, M16
ABIV_RS06795	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABIV_RS06800	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABIV_RS06805	COG0287	Prephenate dehydrogenase
ABIV_RS06810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABIV_RS06825	COG0527	aspartate kinase activity
ABIV_RS06830	COG0494	nUDIX hydrolase
ABIV_RS06835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABIV_RS06840	COG2890	protein-(glutamine-N5) methyltransferase activity
ABIV_RS06845	COG0339	signal peptide processing
ABIV_RS06860	COG0582	viral genome integration into host DNA
ABIV_RS06865	COG2201	protein-glutamate methylesterase activity
ABIV_RS06870	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABIV_RS06875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABIV_RS06885	COG0745	RESPONSE REGULATOR receiver
ABIV_RS06890	COG1185	polyribonucleotide nucleotidyltransferase activity
ABIV_RS06900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABIV_RS06915	COG0659	secondary active sulfate transmembrane transporter activity
ABIV_RS06920	COG1160	GTP binding
ABIV_RS06930	COG1674	ftsk spoiiie
ABIV_RS06930	COG1196	nuclear chromosome segregation
ABIV_RS06935	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABIV_RS06940	COG0440	acetolactate synthase activity
ABIV_RS06945	COG0028	Belongs to the TPP enzyme family
ABIV_RS06955	COG0248	Ppx GppA phosphatase
ABIV_RS06960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABIV_RS06965	COG3706	GGDEF domain
ABIV_RS06970	COG0659	secondary active sulfate transmembrane transporter activity
ABIV_RS06985	COG3118	belongs to the thioredoxin family
ABIV_RS06990	COG1683	Conserved Protein
ABIV_RS06995	COG0037	tRNA processing
ABIV_RS07005	COG4067	protein conserved in archaea
ABIV_RS07005	COG0189	ligase activity
ABIV_RS07020	COG1012	belongs to the aldehyde dehydrogenase family
ABIV_RS07035	COG2259	Doxx family
ABIV_RS07040	COG0410	ABC transporter
ABIV_RS07120	COG3258	Cytochrome c
ABIV_RS07145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABIV_RS07150	COG0303	'Molybdopterin
ABIV_RS07155	COG0697	spore germination
ABIV_RS07165	COG1322	Protein conserved in bacteria
ABIV_RS07170	COG0501	Belongs to the peptidase M48B family
ABIV_RS07175	COG3706	GGDEF domain
ABIV_RS07180	COG0824	Thioesterase
ABIV_RS07185	COG0582	viral genome integration into host DNA
ABIV_RS07215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABIV_RS07245	COG3706	GGDEF domain
ABIV_RS07260	COG1918	ferrous iron import across plasma membrane
ABIV_RS07265	COG1918	ferrous iron import across plasma membrane
ABIV_RS07265	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABIV_RS07275	COG0667	Aldo Keto reductase
ABIV_RS07300	COG1492	cobalamin metabolic process
ABIV_RS07310	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ABIV_RS07315	COG0778	Nitroreductase
ABIV_RS07335	COG1797	cobyrinic acid a,c-diamide synthase activity
ABIV_RS07350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABIV_RS07350	COG1648	precorrin-2 dehydrogenase activity
ABIV_RS07355	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ABIV_RS07385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABIV_RS07400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABIV_RS07415	COG4206	TonB-dependent receptor
ABIV_RS07440	COG4865	methylaspartate mutase activity
ABIV_RS07450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABIV_RS07460	COG3706	GGDEF domain
ABIV_RS07475	COG0702	epimerase
ABIV_RS07490	COG0275	rRNA processing
ABIV_RS07500	COG0776	regulation of translation
ABIV_RS07510	COG3852	Histidine kinase
ABIV_RS07530	COG2863	cytochrome
ABIV_RS07540	COG0642	Histidine kinase
ABIV_RS07545	COG0745	RESPONSE REGULATOR receiver
ABIV_RS07560	COG1132	(ABC) transporter
ABIV_RS07575	COG2356	endonuclease I
ABIV_RS07585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABIV_RS07590	COG0653	protein targeting
ABIV_RS07615	COG0039	L-malate dehydrogenase activity
ABIV_RS07630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABIV_RS07650	COG0484	heat shock protein binding
ABIV_RS07655	COG0789	Transcriptional regulator
ABIV_RS07660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABIV_RS07665	COG0849	cell division
ABIV_RS07675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABIV_RS07695	COG2257	FlhB HrpN YscU SpaS Family
ABIV_RS07705	COG0768	penicillin binding
ABIV_RS07710	COG1338	Plays a role in the flagellum-specific transport system
ABIV_RS07715	COG4191	Histidine kinase
ABIV_RS07755	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABIV_RS07770	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABIV_RS07775	COG0131	Imidazoleglycerol-phosphate dehydratase
ABIV_RS07780	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ABIV_RS07785	COG0741	lytic transglycosylase activity
ABIV_RS07785	COG1388	LysM domain
ABIV_RS07790	COG0084	hydrolase, TatD family'
ABIV_RS07800	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABIV_RS07805	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABIV_RS07810	COG0359	binds to the 23S rRNA
ABIV_RS07825	COG0745	RESPONSE REGULATOR receiver
ABIV_RS07840	COG0163	prenyltransferase activity
ABIV_RS07845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABIV_RS07850	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABIV_RS07855	COG0124	histidyl-tRNA synthetase
ABIV_RS07860	COG1166	arginine decarboxylase activity
ABIV_RS07865	COG1045	serine acetyltransferase
ABIV_RS07870	COG0730	response to heat
ABIV_RS07875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABIV_RS07880	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABIV_RS07890	COG4536	flavin adenine dinucleotide binding
ABIV_RS07905	COG2113	Glycine betaine
ABIV_RS07910	COG4176	ABC-type proline glycine betaine transport system permease component
ABIV_RS07915	COG4175	Glycine betaine
ABIV_RS07945	COG1028	Short-chain dehydrogenase reductase Sdr
ABIV_RS07950	COG5002	protein histidine kinase activity
ABIV_RS07950	COG5001	Diguanylate cyclase
ABIV_RS07960	COG2223	nitrite transmembrane transporter activity
ABIV_RS07965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABIV_RS07970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABIV_RS08000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABIV_RS08005	COG1414	Transcriptional regulator
ABIV_RS08010	COG0693	protein deglycase activity
ABIV_RS08020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABIV_RS08025	COG0513	Belongs to the DEAD box helicase family
ABIV_RS08030	COG0596	Alpha beta hydrolase
ABIV_RS08075	COG0393	Putative heavy-metal-binding
ABIV_RS08100	COG1733	regulation of RNA biosynthetic process
ABIV_RS08105	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABIV_RS08110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABIV_RS08120	COG1187	pseudouridine synthase activity
ABIV_RS08125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABIV_RS08140	COG0519	Catalyzes the synthesis of GMP from XMP
ABIV_RS08140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABIV_RS08145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABIV_RS08150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ABIV_RS08170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABIV_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
ABIV_RS08200	COG0488	(ABC) transporter
ABIV_RS08205	COG1610	YqeY-like protein
ABIV_RS08210	COG3706	GGDEF domain
ABIV_RS08220	COG0840	transmembrane signaling receptor activity
ABIV_RS08260	COG0300	oxidoreductase activity
ABIV_RS08265	COG1757	Na H antiporter
ABIV_RS08270	COG2202	Pas domain
ABIV_RS08270	COG2199	diguanylate cyclase activity
ABIV_RS08270	COG2200	EAL domain
ABIV_RS08275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABIV_RS08280	COG0742	ribosomal rna small subunit methyltransferase
ABIV_RS08300	COG1418	mRNA catabolic process
ABIV_RS08310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABIV_RS08315	COG0552	protein localization to endoplasmic reticulum
ABIV_RS08330	COG5002	protein histidine kinase activity
ABIV_RS08335	COG3258	Cytochrome c
ABIV_RS08350	COG3150	esterase
ABIV_RS08365	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ABIV_RS08375	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABIV_RS08390	COG0783	Belongs to the Dps family
ABIV_RS08395	COG1592	Rubrerythrin
ABIV_RS08405	COG0728	peptidoglycan biosynthetic process
ABIV_RS08410	COG1132	(ABC) transporter
ABIV_RS08415	COG0167	dihydroorotate dehydrogenase activity
ABIV_RS08425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABIV_RS08430	COG1028	Short-chain dehydrogenase reductase Sdr
ABIV_RS08435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABIV_RS08440	COG0750	zinc metalloprotease
ABIV_RS08445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ABIV_RS08465	COG0134	indole-3-glycerol-phosphate synthase activity
ABIV_RS08475	COG0727	PFAM Uncharacterised protein family (UPF0153)
ABIV_RS08480	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ABIV_RS08490	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABIV_RS08490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ABIV_RS08495	COG0028	Belongs to the TPP enzyme family
ABIV_RS08515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABIV_RS08520	COG2176	DNA-directed DNA polymerase activity
ABIV_RS08525	COG0135	phosphoribosylanthranilate isomerase activity
ABIV_RS08530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABIV_RS08535	COG3008	intermembrane lipid transfer
ABIV_RS08535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABIV_RS08540	COG2995	paraquat-inducible protein a
ABIV_RS08550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABIV_RS08575	COG1280	lysine exporter protein (LysE YggA)
ABIV_RS08580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABIV_RS08595	COG0534	Mate efflux family protein
ABIV_RS08600	COG1522	sequence-specific DNA binding
ABIV_RS08610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABIV_RS08620	COG0535	radical SAM domain protein
ABIV_RS08635	COG0352	thiamine-phosphate diphosphorylase activity
ABIV_RS08635	COG0351	phosphomethylpyrimidine kinase
ABIV_RS08650	COG0642	Histidine kinase
ABIV_RS08655	COG0745	RESPONSE REGULATOR receiver
ABIV_RS08660	COG0784	Response regulator, receiver
ABIV_RS08660	COG3437	response regulator, receiver
ABIV_RS08665	COG1666	GTP binding
ABIV_RS08670	COG2233	PERMEase
ABIV_RS08675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ABIV_RS08690	COG2363	Small membrane protein
ABIV_RS08700	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ABIV_RS08705	COG2252	PERMEase
ABIV_RS08710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABIV_RS08715	COG2207	Transcriptional regulator
ABIV_RS08715	COG3708	Transcriptional regulator
ABIV_RS08725	COG5001	Diguanylate cyclase
ABIV_RS08725	COG4251	negative regulation of phosphorylation
ABIV_RS08725	COG3706	GGDEF domain
ABIV_RS08725	COG2203	Gaf domain
ABIV_RS08730	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ABIV_RS08735	COG0432	Pfam Uncharacterised protein family UPF0047
ABIV_RS08750	COG2207	Transcriptional regulator
ABIV_RS08760	COG0640	Transcriptional regulator
ABIV_RS08765	COG2217	Heavy metal translocating P-type atpase
ABIV_RS08770	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ABIV_RS08775	COG2171	N-acyltransferase activity
ABIV_RS08780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABIV_RS08830	COG0375	protein maturation
ABIV_RS08835	COG1024	Enoyl-CoA hydratase
ABIV_RS08835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABIV_RS08840	COG0309	Hydrogenase expression formation protein (HypE)
ABIV_RS08845	COG0409	Hydrogenase expression formation protein
ABIV_RS08850	COG0298	carbon dioxide binding
ABIV_RS08855	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABIV_RS08865	COG2814	Major facilitator Superfamily
ABIV_RS08870	COG0840	transmembrane signaling receptor activity
ABIV_RS08880	COG0733	neurotransmitter:sodium symporter activity
ABIV_RS08890	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABIV_RS08900	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ABIV_RS08905	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ABIV_RS08910	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ABIV_RS08915	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ABIV_RS08925	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ABIV_RS08935	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ABIV_RS08940	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ABIV_RS08960	COG1049	propionate catabolic process, 2-methylcitrate cycle
ABIV_RS08970	COG0697	spore germination
ABIV_RS08980	COG0217	transcriptional regulatory protein
ABIV_RS08985	COG0739	heme binding
ABIV_RS08990	COG2853	Lipoprotein
ABIV_RS09005	COG1611	Belongs to the LOG family
ABIV_RS09015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABIV_RS09020	COG0436	Aminotransferase
ABIV_RS09045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABIV_RS09050	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABIV_RS09060	COG4191	Histidine kinase
ABIV_RS09070	COG1078	dGTPase activity
ABIV_RS09080	COG3123	guanosine phosphorylase activity
ABIV_RS09100	COG0745	RESPONSE REGULATOR receiver
ABIV_RS09105	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABIV_RS09105	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ABIV_RS09110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABIV_RS09120	COG0133	tryptophan synthase activity
ABIV_RS09125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABIV_RS09140	COG0305	Participates in initiation and elongation during chromosome replication
ABIV_RS09145	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABIV_RS09155	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABIV_RS09160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABIV_RS09170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABIV_RS09175	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABIV_RS09180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABIV_RS09190	COG0528	UMP kinase activity
ABIV_RS09195	COG1758	RNA polymerase activity
ABIV_RS09200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABIV_RS09205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABIV_RS09230	COG0193	aminoacyl-tRNA hydrolase activity
ABIV_RS09235	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABIV_RS09245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABIV_RS09250	COG0681	Belongs to the peptidase S26 family
ABIV_RS09255	COG0698	ribose 5-phosphate isomerase
ABIV_RS09295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABIV_RS09305	COG0556	nucleotide-excision repair
ABIV_RS09320	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABIV_RS09325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABIV_RS09330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABIV_RS09335	COG0835	chemotaxis
ABIV_RS09335	COG0784	Response regulator, receiver
ABIV_RS09340	COG0165	Argininosuccinate lyase
ABIV_RS09355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABIV_RS09360	COG0765	amino acid transport
ABIV_RS09370	COG0719	Fe-S assembly protein
ABIV_RS09375	COG0396	ATPase activity
ABIV_RS09380	COG0719	Fe-S assembly protein
ABIV_RS09385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABIV_RS09390	COG2166	iron-sulfur cluster assembly
ABIV_RS09395	COG2151	metal-sulfur cluster biosynthetic enzyme
ABIV_RS09405	COG2199	diguanylate cyclase activity
ABIV_RS09405	COG3287	FIST C domain
ABIV_RS09405	COG2200	EAL domain
ABIV_RS09425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABIV_RS09440	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABIV_RS09450	COG3852	Histidine kinase
ABIV_RS09455	COG4753	response regulator
ABIV_RS09455	COG2207	Transcriptional regulator
ABIV_RS09460	COG4263	nitrous-oxide reductase activity
ABIV_RS09475	COG0437	4 iron, 4 sulfur cluster binding
ABIV_RS09490	COG0348	domain, Protein
ABIV_RS09495	COG1131	(ABC) transporter
ABIV_RS09515	COG0626	cystathionine gamma-synthase activity
ABIV_RS09530	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ABIV_RS09545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABIV_RS09560	COG1999	signal sequence binding
ABIV_RS09565	COG1917	Cupin 2, conserved barrel domain protein
ABIV_RS09565	COG2207	Transcriptional regulator
ABIV_RS09580	COG1301	dicarboxylic acid transport
ABIV_RS09605	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABIV_RS09610	COG0747	negative chemotaxis
ABIV_RS09620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABIV_RS09640	COG2354	Protein conserved in bacteria
ABIV_RS09650	COG0840	transmembrane signaling receptor activity
ABIV_RS09660	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ABIV_RS09665	COG3706	GGDEF domain
ABIV_RS09685	COG3706	GGDEF domain
ABIV_RS09690	COG1131	(ABC) transporter
ABIV_RS09765	COG1858	cytochrome C peroxidase
ABIV_RS09775	COG0189	ligase activity
ABIV_RS09790	COG0716	FMN binding
ABIV_RS09815	COG0784	Response regulator, receiver
ABIV_RS09815	COG2205	protein histidine kinase activity
ABIV_RS09825	COG4608	Belongs to the ABC transporter superfamily
ABIV_RS09830	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABIV_RS09845	COG1355	regulation of microtubule-based process
ABIV_RS09850	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ABIV_RS09855	COG1121	(ABC) transporter
ABIV_RS09860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABIV_RS09865	COG2996	Protein conserved in bacteria
ABIV_RS09875	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABIV_RS09880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABIV_RS09925	COG2274	protein secretion by the type I secretion system
ABIV_RS09980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABIV_RS09985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABIV_RS09990	COG1047	Peptidyl-prolyl cis-trans
ABIV_RS10010	COG1090	epimerase
ABIV_RS10015	COG3279	Response regulator of the LytR AlgR family
ABIV_RS10020	COG3275	phosphorelay sensor kinase activity
ABIV_RS10030	COG0415	Belongs to the DNA photolyase family
ABIV_RS10040	COG0823	Involved in the tonB-independent uptake of proteins
ABIV_RS10050	COG0848	biopolymer transport protein
ABIV_RS10055	COG0811	peptide transport
ABIV_RS10060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABIV_RS10065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABIV_RS10070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABIV_RS10075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABIV_RS10080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABIV_RS10085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABIV_RS10095	COG1475	DNA binding
ABIV_RS10100	COG1192	Involved in chromosome partitioning
ABIV_RS10105	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ABIV_RS10105	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ABIV_RS10115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABIV_RS10120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABIV_RS10125	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABIV_RS10130	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABIV_RS10135	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABIV_RS10140	COG0251	oxidation-reduction process
ABIV_RS10145	COG0358	DNA primase activity
ABIV_RS10155	COG0328	RNA-DNA hybrid ribonuclease activity
ABIV_RS10160	COG0571	ribonuclease III activity
ABIV_RS10165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABIV_RS10175	COG1342	Belongs to the UPF0251 family
ABIV_RS10180	COG0501	Belongs to the peptidase M48B family
ABIV_RS10200	COG2081	HI0933 family
ABIV_RS10205	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABIV_RS10215	COG0706	membrane insertase activity
ABIV_RS10220	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABIV_RS10225	COG0594	ribonuclease P activity
ABIV_RS10230	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ABIV_RS10235	COG0542	response to heat
ABIV_RS10255	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABIV_RS10280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABIV_RS10285	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABIV_RS10290	COG0494	nUDIX hydrolase
ABIV_RS10295	COG0784	Response regulator, receiver
ABIV_RS10295	COG2205	protein histidine kinase activity
ABIV_RS10295	COG2198	Histidine kinase
ABIV_RS10295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABIV_RS10300	COG2855	membrane
ABIV_RS10305	COG0583	DNA-binding transcription factor activity
ABIV_RS10320	COG0138	bifunctional purine biosynthesis protein purh
ABIV_RS10335	COG2151	metal-sulfur cluster biosynthetic enzyme
ABIV_RS10350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABIV_RS10360	COG0741	lytic transglycosylase activity
ABIV_RS10360	COG1196	nuclear chromosome segregation
ABIV_RS10360	COG0739	heme binding
ABIV_RS10365	COG2239	Acts as a magnesium transporter
ABIV_RS10380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ABIV_RS10395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABIV_RS10405	COG3437	response regulator, receiver
ABIV_RS10405	COG0784	Response regulator, receiver
ABIV_RS10415	COG0606	chelatase, subunit chli
ABIV_RS10420	COG0840	transmembrane signaling receptor activity
ABIV_RS10425	COG0242	peptide deformylase activity
ABIV_RS10430	COG0740	serine-type endopeptidase activity
ABIV_RS10435	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABIV_RS10440	COG2304	oxidoreductase activity
ABIV_RS10445	COG2326	polyphosphate kinase activity
ABIV_RS10465	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABIV_RS10515	COG3706	GGDEF domain
ABIV_RS10525	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABIV_RS10635	COG0784	Response regulator, receiver
ABIV_RS10640	COG4771	TonB-dependent receptor
ABIV_RS10680	COG0739	heme binding
ABIV_RS10685	COG0285	dihydrofolate synthase activity
ABIV_RS10695	COG0495	leucyl-tRNA aminoacylation
ABIV_RS10715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABIV_RS10720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABIV_RS10725	COG1862	Preprotein translocase
ABIV_RS10730	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ABIV_RS10735	COG0617	tRNA 3'-terminal CCA addition
ABIV_RS10740	COG0668	transmembrane transport
ABIV_RS10745	COG0442	prolyl-tRNA aminoacylation
ABIV_RS10750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABIV_RS10755	COG0142	geranyltranstransferase activity
ABIV_RS10765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABIV_RS10770	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABIV_RS10800	COG0642	Histidine kinase
ABIV_RS10805	COG0745	RESPONSE REGULATOR receiver
ABIV_RS10810	COG0191	fructose-bisphosphate aldolase activity
ABIV_RS10815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABIV_RS10820	COG0745	RESPONSE REGULATOR receiver
ABIV_RS10825	COG0642	Histidine kinase
ABIV_RS10835	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ABIV_RS10840	COG5016	pyruvate
ABIV_RS10840	COG0511	ligase activity, forming carbon-carbon bonds
ABIV_RS10845	COG3630	sodium ion export across plasma membrane
ABIV_RS10855	COG2404	hydrolase activity, acting on ester bonds
ABIV_RS10865	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABIV_RS10875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABIV_RS10880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABIV_RS10885	COG4597	amino acid ABC transporter
ABIV_RS10890	COG0765	amino acid transport
ABIV_RS10895	COG1126	abc transporter atp-binding protein
ABIV_RS10910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABIV_RS10920	COG3287	FIST C domain
ABIV_RS10920	COG2199	diguanylate cyclase activity
ABIV_RS10920	COG2200	EAL domain
ABIV_RS10930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABIV_RS10945	COG4772	TonB-dependent receptor
ABIV_RS10965	COG3852	Histidine kinase
ABIV_RS10970	COG4753	response regulator
ABIV_RS10970	COG2207	Transcriptional regulator
ABIV_RS10975	COG4773	Receptor
ABIV_RS10990	COG0811	peptide transport
ABIV_RS10995	COG0811	peptide transport
ABIV_RS11000	COG0848	biopolymer transport protein
ABIV_RS11020	COG3437	response regulator, receiver
ABIV_RS11020	COG0784	Response regulator, receiver
ABIV_RS11030	COG4771	TonB-dependent receptor
ABIV_RS11035	COG1132	(ABC) transporter
ABIV_RS11035	COG2375	cellular response to nickel ion
ABIV_RS11040	COG1132	(ABC) transporter
ABIV_RS11055	COG1971	Probably functions as a manganese efflux pump
ABIV_RS11080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABIV_RS11085	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ABIV_RS11100	COG0189	ligase activity
ABIV_RS11115	COG2966	Psort location CytoplasmicMembrane, score
ABIV_RS11135	COG4221	oxidoreductase activity
ABIV_RS11150	COG0488	(ABC) transporter
ABIV_RS11165	COG0335	large ribosomal subunit rRNA binding
ABIV_RS11170	COG0336	Belongs to the RNA methyltransferase TrmD family
ABIV_RS11180	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABIV_RS11185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABIV_RS11190	COG0356	it plays a direct role in the translocation of protons across the membrane
ABIV_RS11200	COG1074	ATP-dependent DNA helicase activity
ABIV_RS11210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABIV_RS11215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABIV_RS11225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABIV_RS11240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABIV_RS11250	COG0303	'Molybdopterin
ABIV_RS11255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABIV_RS11260	COG0720	synthase
ABIV_RS11265	COG0602	queuosine metabolic process
ABIV_RS11275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABIV_RS11280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABIV_RS11285	COG0825	malonyl-CoA metabolic process
ABIV_RS11290	COG0537	adenosine 5'-monophosphoramidase activity
ABIV_RS11295	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABIV_RS11300	COG0072	phenylalanine-tRNA ligase activity
ABIV_RS11300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABIV_RS11305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABIV_RS11310	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABIV_RS11315	COG1185	polyribonucleotide nucleotidyltransferase activity
ABIV_RS11315	COG0539	negative regulation of cytoplasmic translation
ABIV_RS11320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABIV_RS11325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABIV_RS11330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABIV_RS11330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABIV_RS11335	COG0779	Required for maturation of 30S ribosomal subunits
ABIV_RS11340	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABIV_RS11345	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABIV_RS11355	COG0083	homoserine kinase activity
ABIV_RS11365	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ABIV_RS11370	COG1388	LysM domain
ABIV_RS11370	COG4942	peptidase
ABIV_RS11380	COG0157	Belongs to the NadC ModD family
ABIV_RS11390	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABIV_RS11400	COG4773	Receptor
ABIV_RS11410	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ABIV_RS11415	COG4773	Receptor
ABIV_RS11455	COG3278	Belongs to the heme-copper respiratory oxidase family
ABIV_RS11460	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABIV_RS11465	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABIV_RS11470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABIV_RS11475	COG0210	DNA helicase
ABIV_RS11485	COG1242	4 iron, 4 sulfur cluster binding
ABIV_RS11490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ABIV_RS11495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABIV_RS11500	COG3118	belongs to the thioredoxin family
ABIV_RS11505	COG0492	ferredoxin-NADP+ reductase activity
ABIV_RS11510	COG1115	amino acid carrier protein
ABIV_RS11520	COG3118	belongs to the thioredoxin family
ABIV_RS11525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABIV_RS11535	COG0791	NLP P60 protein
ABIV_RS11555	COG0424	maF-like protein
ABIV_RS11560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABIV_RS11565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABIV_RS11575	COG0019	diaminopimelate decarboxylase activity
ABIV_RS11580	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ABIV_RS11585	COG0149	triose-phosphate isomerase activity
ABIV_RS11590	COG0126	phosphoglycerate kinase activity
ABIV_RS11600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABIV_RS11610	COG0018	arginyl-trna synthetase
ABIV_RS11620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABIV_RS11625	COG0204	Acyl-transferase
ABIV_RS11635	COG0047	phosphoribosylformylglycinamidine synthase activity
ABIV_RS11640	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABIV_RS11645	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABIV_RS11650	COG0793	Belongs to the peptidase S41A family
ABIV_RS11665	COG0585	pseudouridine synthase activity
ABIV_RS11680	COG2205	protein histidine kinase activity
ABIV_RS11700	COG4208	sulfate ABC transporter
ABIV_RS11710	COG3842	ATPase activity
ABIV_RS11735	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ABIV_RS11740	COG0205	6-phosphofructokinase activity
ABIV_RS11745	COG0628	permease
ABIV_RS11760	COG0156	8-amino-7-oxononanoate synthase activity
ABIV_RS11770	COG0288	reversible hydration of carbon dioxide
ABIV_RS11780	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABIV_RS11785	COG2205	protein histidine kinase activity
ABIV_RS11785	COG0784	Response regulator, receiver
ABIV_RS11790	COG0784	Response regulator, receiver
ABIV_RS11790	COG2205	protein histidine kinase activity
ABIV_RS11805	COG2121	Domain of unknown function (DUF374)
ABIV_RS11810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABIV_RS11820	COG0195	Participates in both transcription termination and antitermination
ABIV_RS11825	COG0215	cysteine-tRNA ligase activity
ABIV_RS11830	COG1620	l-lactate permease
ABIV_RS11835	COG3842	ATPase activity
ABIV_RS11840	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABIV_RS11845	COG1840	ABC-type Fe3 transport system, periplasmic component
ABIV_RS11850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABIV_RS11855	COG0629	single-stranded DNA binding
ABIV_RS11860	COG0360	Binds together with S18 to 16S ribosomal RNA
ABIV_RS11865	COG1466	dna polymerase III delta subunit
ABIV_RS11885	COG0557	exoribonuclease II activity
ABIV_RS11895	COG3852	Histidine kinase
ABIV_RS11900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABIV_RS11930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABIV_RS11945	COG0436	Aminotransferase
ABIV_RS11955	COG0343	queuine tRNA-ribosyltransferase activity
ABIV_RS11960	COG1450	Type ii and iii secretion system protein
ABIV_RS11985	COG4962	Type ii secretion system protein e
ABIV_RS12010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABIV_RS12015	COG1393	Belongs to the ArsC family
ABIV_RS12025	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ABIV_RS12035	COG0560	Phosphoserine phosphatase
ABIV_RS12040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABIV_RS12055	COG3437	response regulator, receiver
ABIV_RS12055	COG0784	Response regulator, receiver
ABIV_RS12060	COG0736	holo-[acyl-carrier-protein] synthase activity
ABIV_RS12065	COG0601	transmembrane transport
ABIV_RS12070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABIV_RS12080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABIV_RS12145	COG1706	bacterial-type flagellum-dependent cell motility
ABIV_RS12150	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABIV_RS12155	COG0418	dihydroorotase activity
ABIV_RS12165	COG0004	ammonium transporteR
ABIV_RS12170	COG0347	Belongs to the P(II) protein family
ABIV_RS12175	COG0004	ammonium transporteR
ABIV_RS12190	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ABIV_RS12200	COG2962	Rard protein
ABIV_RS12215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABIV_RS12220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABIV_RS12245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABIV_RS12300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABIV_RS12305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABIV_RS12305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABIV_RS12330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ABIV_RS12340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ABIV_RS12355	COG0745	RESPONSE REGULATOR receiver
ABIV_RS12365	COG3290	protein histidine kinase activity
ABIV_RS12380	COG3437	response regulator, receiver
ABIV_RS12405	COG0129	dihydroxy-acid dehydratase activity
ABIV_RS12415	COG0745	RESPONSE REGULATOR receiver
ABIV_RS12420	COG0642	Histidine kinase
ABIV_RS12435	COG1490	D-aminoacyl-tRNA deacylase activity
ABIV_RS12440	COG1401	restriction endodeoxyribonuclease activity
ABIV_RS12455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABIV_RS12460	COG2095	MarC family integral membrane protein
ABIV_RS12465	COG4232	protein-disulfide reductase activity
ABIV_RS12480	COG2199	diguanylate cyclase activity
ABIV_RS12480	COG3287	FIST C domain
ABIV_RS12480	COG2200	EAL domain
ABIV_RS12495	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ABIV_RS12505	COG0443	Heat shock 70 kDa protein
ABIV_RS12510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABIV_RS12515	COG1420	regulation of RNA biosynthetic process
ABIV_RS12525	COG0745	RESPONSE REGULATOR receiver
ABIV_RS12535	COG0101	tRNA pseudouridine synthase activity
ABIV_RS12550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABIV_RS12555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABIV_RS12560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABIV_RS12570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABIV_RS12575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABIV_RS12600	COG4122	O-methyltransferase activity
ABIV_RS12605	COG0367	asparagine synthase
ABIV_RS12610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABIV_RS12670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABIV_RS12675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ABIV_RS12680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABIV_RS12680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABIV_RS12685	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ABIV_RS12690	COG2089	acid synthase
ABIV_RS12700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABIV_RS12715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABIV_RS12720	COG0148	phosphopyruvate hydratase activity
ABIV_RS12735	COG0475	glutathione-regulated potassium exporter activity
ABIV_RS12735	COG0569	domain protein
ABIV_RS12740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABIV_RS12760	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ABIV_RS12770	COG0747	negative chemotaxis
ABIV_RS12775	COG0745	RESPONSE REGULATOR receiver
ABIV_RS12785	COG0243	molybdopterin cofactor binding
ABIV_RS12790	COG1979	alcohol dehydrogenase
ABIV_RS12800	COG1007	ATP synthesis coupled electron transport
ABIV_RS12810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABIV_RS12815	COG0713	ATP synthesis coupled electron transport
ABIV_RS12820	COG0839	Belongs to the complex I subunit 6 family
ABIV_RS12825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABIV_RS12830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABIV_RS12850	COG0649	NAD binding
ABIV_RS12860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABIV_RS12865	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABIV_RS12905	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ABIV_RS12915	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABIV_RS12925	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABIV_RS12930	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABIV_RS12935	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABIV_RS12940	COG1077	Cell shape determining protein MreB Mrl
ABIV_RS12950	COG0307	riboflavin synthase, alpha
ABIV_RS12955	COG0445	tRNA wobble uridine modification
ABIV_RS12965	COG0504	CTP synthase activity
ABIV_RS12970	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ABIV_RS12970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABIV_RS12985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABIV_RS13005	COG0587	DNA-directed DNA polymerase activity
ABIV_RS13010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABIV_RS13035	COG0315	cyclic pyranopterin monophosphate synthase activity
ABIV_RS13040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABIV_RS13075	COG0670	Belongs to the BI1 family
ABIV_RS13080	COG0352	thiamine-phosphate diphosphorylase activity
ABIV_RS13085	COG4106	trans-aconitate 2-methyltransferase activity
ABIV_RS13090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABIV_RS13095	COG0233	cytoplasmic translational termination
ABIV_RS13100	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABIV_RS13110	COG2814	Major facilitator Superfamily
ABIV_RS13120	COG0527	aspartate kinase activity
ABIV_RS13125	COG0745	RESPONSE REGULATOR receiver
ABIV_RS13135	COG1917	Cupin 2, conserved barrel domain protein
ABIV_RS13140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABIV_RS13145	COG0456	acetyltransferase
ABIV_RS13155	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABIV_RS13160	COG3022	response to hydroperoxide
ABIV_RS13165	COG3012	SEC-C Motif Domain Protein
ABIV_RS13170	COG1555	photosystem II stabilization
ABIV_RS13185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABIV_RS13195	COG0546	phosphoglycolate phosphatase activity
ABIV_RS13215	COG1253	flavin adenine dinucleotide binding
ABIV_RS13220	COG2703	oxygen carrier activity
ABIV_RS13260	COG2081	HI0933 family
ABIV_RS13270	COG1959	2 iron, 2 sulfur cluster binding
ABIV_RS13290	COG0175	sulfate reduction
ABIV_RS13295	COG2895	sulfate adenylyltransferase (ATP) activity
ABIV_RS13320	COG0840	transmembrane signaling receptor activity
ABIV_RS13345	COG3043	anaerobic respiration
ABIV_RS13350	COG0348	domain, Protein
ABIV_RS13355	COG0437	4 iron, 4 sulfur cluster binding
ABIV_RS13360	COG0243	molybdopterin cofactor binding
ABIV_RS13380	COG1408	metallophosphoesterase
ABIV_RS13400	COG0840	transmembrane signaling receptor activity
ABIV_RS13410	COG0071	Belongs to the small heat shock protein (HSP20) family
ABIV_RS13415	COG1217	gtp-binding protein TYPA
ABIV_RS13425	COG0577	efflux transmembrane transporter activity
ABIV_RS13425	COG1136	(ABC) transporter
ABIV_RS13450	COG1408	metallophosphoesterase
ABIV_RS13455	COG0745	RESPONSE REGULATOR receiver
ABIV_RS13460	COG5002	protein histidine kinase activity
ABIV_RS13465	COG3437	response regulator, receiver
ABIV_RS13465	COG0784	Response regulator, receiver
ABIV_RS13475	COG2391	methyltransferase activity
ABIV_RS13480	COG0425	Belongs to the sulfur carrier protein TusA family
ABIV_RS13485	COG2066	Belongs to the glutaminase family
ABIV_RS13515	COG0745	RESPONSE REGULATOR receiver
ABIV_RS13520	COG0642	Histidine kinase
ABIV_RS13525	COG2860	membrane
ABIV_RS13530	COG3706	GGDEF domain
ABIV_RS13540	COG2201	protein-glutamate methylesterase activity
ABIV_RS13550	COG0697	spore germination
ABIV_RS13555	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group