locus-tag	class	description
ABED_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABED_RS00010	COG0592	DNA-directed DNA polymerase activity
ABED_RS00015	COG0187	DNA topoisomerase II activity
ABED_RS00020	COG0492	ferredoxin-NADP+ reductase activity
ABED_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABED_RS00035	COG1238	metal cluster binding
ABED_RS00040	COG0500	methyltransferase
ABED_RS00045	COG3842	ATPase activity
ABED_RS00090	COG0564	pseudouridine synthase activity
ABED_RS00095	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABED_RS00100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABED_RS00105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABED_RS00115	COG0824	Thioesterase
ABED_RS00135	COG0604	alcohol dehydrogenase
ABED_RS00140	COG1733	regulation of RNA biosynthetic process
ABED_RS00145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABED_RS00150	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABED_RS00165	COG1620	l-lactate permease
ABED_RS00170	COG0745	RESPONSE REGULATOR receiver
ABED_RS00175	COG3852	Histidine kinase
ABED_RS00180	COG1556	Lactate utilization protein
ABED_RS00185	COG1139	Iron-sulfur cluster binding protein
ABED_RS00190	COG0247	lactate metabolic process
ABED_RS00195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABED_RS00200	COG0511	ligase activity, forming carbon-carbon bonds
ABED_RS00205	COG0439	Biotin carboxylase
ABED_RS00210	COG0513	Belongs to the DEAD box helicase family
ABED_RS00215	COG0306	phosphate transporter
ABED_RS00225	COG0367	asparagine synthase
ABED_RS00235	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABED_RS00240	COG1981	membrane
ABED_RS00245	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ABED_RS00245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABED_RS00250	COG1187	pseudouridine synthase activity
ABED_RS00255	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ABED_RS00255	COG0517	IMP dehydrogenase activity
ABED_RS00260	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ABED_RS00265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABED_RS00270	COG0107	imidazoleglycerol-phosphate synthase activity
ABED_RS00285	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABED_RS00290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABED_RS00295	COG0724	RNA recognition motif
ABED_RS00300	COG0745	RESPONSE REGULATOR receiver
ABED_RS00305	COG0642	Histidine kinase
ABED_RS00325	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABED_RS00360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABED_RS00365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABED_RS00370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABED_RS00385	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABED_RS00390	COG0746	molybdenum cofactor guanylyltransferase activity
ABED_RS00395	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABED_RS00400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABED_RS00405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABED_RS00410	COG0268	Binds directly to 16S ribosomal RNA
ABED_RS00415	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABED_RS00425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABED_RS00430	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ABED_RS00435	COG0573	inorganic phosphate transmembrane transporter activity
ABED_RS00440	COG0581	inorganic phosphate transmembrane transporter activity
ABED_RS00445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABED_RS00450	COG0704	Plays a role in the regulation of phosphate uptake
ABED_RS00460	COG0745	RESPONSE REGULATOR receiver
ABED_RS00465	COG5002	protein histidine kinase activity
ABED_RS00470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABED_RS00475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABED_RS00485	COG0546	phosphoglycolate phosphatase activity
ABED_RS00505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABED_RS00510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABED_RS00515	COG1854	S-ribosylhomocysteine lyase activity
ABED_RS00530	COG1686	Belongs to the peptidase S11 family
ABED_RS00545	COG0646	methionine synthase
ABED_RS00545	COG1410	methionine synthase
ABED_RS00565	COG0140	phosphoribosyl-ATP diphosphatase activity
ABED_RS00565	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABED_RS00575	COG0489	protein tyrosine kinase activity
ABED_RS00580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABED_RS00590	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABED_RS00590	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABED_RS00600	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABED_RS00610	COG0505	Belongs to the CarA family
ABED_RS00620	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABED_RS00625	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABED_RS00630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABED_RS00635	COG2353	YceI-like domain
ABED_RS00640	COG1846	Transcriptional regulator
ABED_RS00645	COG2353	YceI-like domain
ABED_RS00665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABED_RS00670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABED_RS00675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABED_RS00680	COG0237	dephospho-CoA kinase activity
ABED_RS00685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABED_RS00690	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABED_RS00695	COG0456	acetyltransferase
ABED_RS00725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABED_RS00730	COG0254	rRNA binding
ABED_RS00735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ABED_RS00750	COG0436	Aminotransferase
ABED_RS00755	COG0460	homoserine dehydrogenase
ABED_RS00765	COG0575	Belongs to the CDS family
ABED_RS00770	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABED_RS00785	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABED_RS00790	COG0023	Translation Initiation Factor
ABED_RS00795	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABED_RS00795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABED_RS00800	COG1324	tolerance protein
ABED_RS00805	COG2022	thiamine diphosphate biosynthetic process
ABED_RS00860	COG0840	transmembrane signaling receptor activity
ABED_RS00880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABED_RS00890	COG1346	cytolysis
ABED_RS00900	COG3766	membrane
ABED_RS00905	COG1301	dicarboxylic acid transport
ABED_RS00925	COG4589	Belongs to the CDS family
ABED_RS00935	COG0318	PFAM AMP-dependent synthetase and ligase
ABED_RS00935	COG0204	Acyl-transferase
ABED_RS00940	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ABED_RS00955	COG0666	response to abiotic stimulus
ABED_RS00965	COG0418	dihydroorotase activity
ABED_RS00975	COG1706	bacterial-type flagellum-dependent cell motility
ABED_RS01010	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ABED_RS01040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABED_RS01045	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABED_RS01050	COG0601	transmembrane transport
ABED_RS01055	COG0736	holo-[acyl-carrier-protein] synthase activity
ABED_RS01060	COG0786	glutamate:sodium symporter activity
ABED_RS01065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABED_RS01075	COG0560	Phosphoserine phosphatase
ABED_RS01085	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ABED_RS01090	COG3248	Nucleoside-binding outer membrane protein
ABED_RS01095	COG1393	Belongs to the ArsC family
ABED_RS01100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABED_RS01105	COG0343	queuine tRNA-ribosyltransferase activity
ABED_RS01115	COG0436	Aminotransferase
ABED_RS01135	COG2861	carbohydrate metabolic process
ABED_RS01140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABED_RS01145	COG0557	exoribonuclease II activity
ABED_RS01150	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ABED_RS01160	COG0360	Binds together with S18 to 16S ribosomal RNA
ABED_RS01165	COG0629	single-stranded DNA binding
ABED_RS01170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABED_RS01180	COG0215	cysteine-tRNA ligase activity
ABED_RS01185	COG0195	Participates in both transcription termination and antitermination
ABED_RS01195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABED_RS01200	COG2121	Domain of unknown function (DUF374)
ABED_RS01215	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABED_RS01225	COG0288	reversible hydration of carbon dioxide
ABED_RS01230	COG0156	8-amino-7-oxononanoate synthase activity
ABED_RS01235	COG0792	nuclease activity
ABED_RS01255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABED_RS01265	COG0540	Belongs to the ATCase OTCase family
ABED_RS01270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABED_RS01290	COG2824	Alkylphosphonate utilization operon protein PhnA
ABED_RS01295	COG1451	nucleotide metabolic process
ABED_RS01300	COG0730	response to heat
ABED_RS01325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABED_RS01335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ABED_RS01340	COG0372	Belongs to the citrate synthase family
ABED_RS01345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABED_RS01350	COG2828	Protein conserved in bacteria
ABED_RS01360	COG1335	isochorismatase
ABED_RS01370	COG0181	hydroxymethylbilane synthase activity
ABED_RS01380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABED_RS01385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABED_RS01390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABED_RS01395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABED_RS01400	COG0450	alkyl hydroperoxide reductase
ABED_RS01410	COG0105	UTP biosynthetic process
ABED_RS01420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABED_RS01425	COG0416	fatty acid biosynthetic process
ABED_RS01430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABED_RS01450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABED_RS01455	COG1053	succinate dehydrogenase
ABED_RS01465	COG1007	ATP synthesis coupled electron transport
ABED_RS01475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABED_RS01480	COG0713	ATP synthesis coupled electron transport
ABED_RS01485	COG0839	Belongs to the complex I subunit 6 family
ABED_RS01490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABED_RS01495	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABED_RS01500	COG1034	ATP synthesis coupled electron transport
ABED_RS01505	COG0372	Belongs to the citrate synthase family
ABED_RS01520	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABED_RS01520	COG0649	NAD binding
ABED_RS01525	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABED_RS01530	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABED_RS01535	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ABED_RS01540	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABED_RS01545	COG3610	response to peptide
ABED_RS01550	COG2966	Psort location CytoplasmicMembrane, score
ABED_RS01565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABED_RS01590	COG4774	siderophore transport
ABED_RS01610	COG4771	TonB-dependent receptor
ABED_RS01620	COG1971	Probably functions as a manganese efflux pump
ABED_RS01640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABED_RS01645	COG1333	cytochrome c biogenesis protein
ABED_RS01645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABED_RS01650	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ABED_RS01655	COG3005	denitrification pathway
ABED_RS01665	COG2199	diguanylate cyclase activity
ABED_RS01665	COG3287	FIST C domain
ABED_RS01665	COG2200	EAL domain
ABED_RS01670	COG0840	transmembrane signaling receptor activity
ABED_RS01690	COG3043	anaerobic respiration
ABED_RS01695	COG0348	domain, Protein
ABED_RS01700	COG0437	4 iron, 4 sulfur cluster binding
ABED_RS01705	COG0243	molybdopterin cofactor binding
ABED_RS01715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABED_RS01720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABED_RS01730	COG4753	response regulator
ABED_RS01730	COG2207	Transcriptional regulator
ABED_RS01735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABED_RS01740	COG1648	precorrin-2 dehydrogenase activity
ABED_RS01740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABED_RS01755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABED_RS01760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABED_RS01765	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABED_RS01775	COG2404	hydrolase activity, acting on ester bonds
ABED_RS01780	COG1832	CoA-binding protein
ABED_RS01785	COG0642	Histidine kinase
ABED_RS01790	COG0745	RESPONSE REGULATOR receiver
ABED_RS01795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABED_RS01800	COG0191	fructose-bisphosphate aldolase activity
ABED_RS01820	COG0811	peptide transport
ABED_RS01830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABED_RS01835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABED_RS01845	COG0142	geranyltranstransferase activity
ABED_RS01850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABED_RS01855	COG0442	prolyl-tRNA aminoacylation
ABED_RS01860	COG0668	transmembrane transport
ABED_RS01865	COG0617	tRNA 3'-terminal CCA addition
ABED_RS01880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ABED_RS01885	COG1862	Preprotein translocase
ABED_RS01890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABED_RS01895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABED_RS01910	COG1360	Flagellar Motor Protein
ABED_RS01915	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ABED_RS01925	COG0495	leucyl-tRNA aminoacylation
ABED_RS01935	COG0285	dihydrofolate synthase activity
ABED_RS01965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABED_RS01985	COG0745	RESPONSE REGULATOR receiver
ABED_RS01990	COG0642	Histidine kinase
ABED_RS01995	COG2081	HI0933 family
ABED_RS02000	COG0840	transmembrane signaling receptor activity
ABED_RS02015	COG5002	protein histidine kinase activity
ABED_RS02020	COG1692	metallophosphoesterase
ABED_RS02035	COG2226	methyltransferase
ABED_RS02040	COG1570	exodeoxyribonuclease VII activity
ABED_RS02045	COG0835	chemotaxis
ABED_RS02050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABED_RS02055	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABED_RS02060	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABED_RS02070	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABED_RS02075	COG0459	protein refolding
ABED_RS02085	COG0745	RESPONSE REGULATOR receiver
ABED_RS02090	COG1408	metallophosphoesterase
ABED_RS02115	COG1136	(ABC) transporter
ABED_RS02135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABED_RS02140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABED_RS02145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABED_RS02150	COG0352	thiamine-phosphate diphosphorylase activity
ABED_RS02155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABED_RS02165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABED_RS02170	COG2264	protein methyltransferase activity
ABED_RS02175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABED_RS02180	COG0784	Response regulator, receiver
ABED_RS02180	COG3437	response regulator, receiver
ABED_RS02195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABED_RS02210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABED_RS02220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABED_RS02260	COG1132	(ABC) transporter
ABED_RS02280	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABED_RS02285	COG1090	epimerase
ABED_RS02290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABED_RS02310	COG0481	GTPase activity
ABED_RS02315	COG1937	Protein conserved in bacteria
ABED_RS02330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABED_RS02340	COG0482	sulfurtransferase activity
ABED_RS02345	COG0482	sulfurtransferase activity
ABED_RS02350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABED_RS02355	COG0006	proline dipeptidase activity
ABED_RS02360	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABED_RS02365	COG0402	S-adenosylhomocysteine deaminase activity
ABED_RS02370	COG0616	signal peptide processing
ABED_RS02380	COG0280	phosphate acetyltransferase
ABED_RS02385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABED_RS02395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABED_RS02400	COG2176	DNA-directed DNA polymerase activity
ABED_RS02430	COG2176	DNA-directed DNA polymerase activity
ABED_RS02440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABED_RS02455	COG5002	protein histidine kinase activity
ABED_RS02500	COG1546	Belongs to the CinA family
ABED_RS02500	COG1058	Belongs to the CinA family
ABED_RS02505	COG0579	oxidoreductase
ABED_RS02510	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABED_RS02525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABED_RS02545	COG0745	RESPONSE REGULATOR receiver
ABED_RS02550	COG4585	Histidine kinase
ABED_RS02565	COG0667	Aldo Keto reductase
ABED_RS02570	COG0306	phosphate transporter
ABED_RS02575	COG0840	transmembrane signaling receptor activity
ABED_RS02585	COG0840	transmembrane signaling receptor activity
ABED_RS02590	COG0824	Thioesterase
ABED_RS02600	COG0501	Belongs to the peptidase M48B family
ABED_RS02605	COG1322	Protein conserved in bacteria
ABED_RS02625	COG0037	tRNA processing
ABED_RS02645	COG0052	Belongs to the universal ribosomal protein uS2 family
ABED_RS02650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABED_RS02655	COG1136	(ABC) transporter
ABED_RS02665	COG0194	GDP metabolic process
ABED_RS02670	COG5001	Diguanylate cyclase
ABED_RS02670	COG5002	protein histidine kinase activity
ABED_RS02675	COG2217	Heavy metal translocating P-type atpase
ABED_RS02690	COG4608	Belongs to the ABC transporter superfamily
ABED_RS02695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABED_RS02700	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABED_RS02710	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ABED_RS02715	COG1121	(ABC) transporter
ABED_RS02720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABED_RS02725	COG2996	Protein conserved in bacteria
ABED_RS02730	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABED_RS02750	COG0210	DNA helicase
ABED_RS02755	COG0569	domain protein
ABED_RS02755	COG0475	glutathione-regulated potassium exporter activity
ABED_RS02760	COG0525	valine-tRNA ligase activity
ABED_RS02765	COG4895	conserved protein (DUF2196)
ABED_RS02775	COG2814	Major facilitator Superfamily
ABED_RS02780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABED_RS02800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABED_RS02805	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABED_RS02810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABED_RS02820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABED_RS02850	COG0840	transmembrane signaling receptor activity
ABED_RS02855	COG0840	transmembrane signaling receptor activity
ABED_RS02880	COG0439	Biotin carboxylase
ABED_RS02885	COG2151	metal-sulfur cluster biosynthetic enzyme
ABED_RS02890	COG2166	iron-sulfur cluster assembly
ABED_RS02895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABED_RS02905	COG0396	ATPase activity
ABED_RS02910	COG0719	Fe-S assembly protein
ABED_RS02920	COG2906	2 iron, 2 sulfur cluster binding
ABED_RS02920	COG0822	iron-sulfur transferase activity
ABED_RS02920	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ABED_RS02925	COG2239	Acts as a magnesium transporter
ABED_RS02930	COG3706	GGDEF domain
ABED_RS02935	COG0165	Argininosuccinate lyase
ABED_RS02940	COG0784	Response regulator, receiver
ABED_RS02940	COG0835	chemotaxis
ABED_RS02945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABED_RS02950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABED_RS02960	COG0556	nucleotide-excision repair
ABED_RS02970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABED_RS02990	COG0840	transmembrane signaling receptor activity
ABED_RS03010	COG4191	Histidine kinase
ABED_RS03015	COG0840	transmembrane signaling receptor activity
ABED_RS03035	COG0698	ribose 5-phosphate isomerase
ABED_RS03040	COG0681	Belongs to the peptidase S26 family
ABED_RS03045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABED_RS03050	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABED_RS03055	COG0193	aminoacyl-tRNA hydrolase activity
ABED_RS03070	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABED_RS03080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABED_RS03095	COG0528	UMP kinase activity
ABED_RS03105	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABED_RS03110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABED_RS03115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABED_RS03125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABED_RS03130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABED_RS03140	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABED_RS03150	COG0305	Participates in initiation and elongation during chromosome replication
ABED_RS03165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABED_RS03175	COG2089	acid synthase
ABED_RS03180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ABED_RS03190	COG1083	cytidylyl-transferase
ABED_RS03195	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABED_RS03205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABED_RS03225	COG1028	Short-chain dehydrogenase reductase Sdr
ABED_RS03240	COG0110	maltose O-acetyltransferase activity
ABED_RS03270	COG1086	Polysaccharide biosynthesis protein
ABED_RS03295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABED_RS03300	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ABED_RS03305	COG1086	Polysaccharide biosynthesis protein
ABED_RS03315	COG1793	dna ligase
ABED_RS03320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABED_RS03325	COG0133	tryptophan synthase activity
ABED_RS03335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABED_RS03345	COG0848	biopolymer transport protein
ABED_RS03365	COG1136	(ABC) transporter
ABED_RS03365	COG0577	efflux transmembrane transporter activity
ABED_RS03370	COG1136	(ABC) transporter
ABED_RS03370	COG0577	efflux transmembrane transporter activity
ABED_RS03415	COG0735	belongs to the Fur family
ABED_RS03425	COG0114	fumarate hydratase activity
ABED_RS03435	COG3920	Histidine kinase
ABED_RS03440	COG0784	Response regulator, receiver
ABED_RS03445	COG4774	siderophore transport
ABED_RS03450	COG3128	pkhd-type hydroxylase
ABED_RS03460	COG4771	TonB-dependent receptor
ABED_RS03480	COG1966	Carbon starvation protein
ABED_RS03485	COG0012	GTP binding
ABED_RS03505	COG3123	guanosine phosphorylase activity
ABED_RS03515	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ABED_RS03520	COG0585	pseudouridine synthase activity
ABED_RS03530	COG0840	transmembrane signaling receptor activity
ABED_RS03535	COG0632	four-way junction helicase activity
ABED_RS03540	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABED_RS03565	COG0051	transcription antitermination factor activity, RNA binding
ABED_RS03570	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABED_RS03575	COG0088	Forms part of the polypeptide exit tunnel
ABED_RS03580	COG0089	rRNA binding
ABED_RS03585	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABED_RS03590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABED_RS03595	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABED_RS03600	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABED_RS03605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABED_RS03610	COG0255	Belongs to the universal ribosomal protein uL29 family
ABED_RS03615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABED_RS03620	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABED_RS03625	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABED_RS03630	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABED_RS03635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABED_RS03640	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABED_RS03645	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABED_RS03650	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABED_RS03655	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABED_RS03660	COG0200	Binds to the 23S rRNA
ABED_RS03665	COG0201	protein transport
ABED_RS03670	COG0024	Methionine aminopeptidase
ABED_RS03675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABED_RS03680	COG1573	uracil-dna glycosylase
ABED_RS03690	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABED_RS03700	COG1032	radical SAM domain protein
ABED_RS03710	COG0563	adenylate kinase activity
ABED_RS03730	COG1064	alcohol dehydrogenase
ABED_RS03735	COG1979	alcohol dehydrogenase
ABED_RS03740	COG0840	transmembrane signaling receptor activity
ABED_RS03745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABED_RS03750	COG0322	excinuclease ABC activity
ABED_RS03755	COG0840	transmembrane signaling receptor activity
ABED_RS03760	COG0840	transmembrane signaling receptor activity
ABED_RS03765	COG0840	transmembrane signaling receptor activity
ABED_RS03770	COG0840	transmembrane signaling receptor activity
ABED_RS03820	COG3706	GGDEF domain
ABED_RS03825	COG0708	Exodeoxyribonuclease III
ABED_RS03845	COG3040	lipid binding
ABED_RS03860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABED_RS03870	COG2200	EAL domain
ABED_RS03875	COG3279	Response regulator of the LytR AlgR family
ABED_RS03880	COG3275	phosphorelay sensor kinase activity
ABED_RS03885	COG1233	COG1233 Phytoene dehydrogenase and related
ABED_RS03890	COG0415	Belongs to the DNA photolyase family
ABED_RS03910	COG0166	Belongs to the GPI family
ABED_RS03955	COG0840	transmembrane signaling receptor activity
ABED_RS03960	COG1942	4-Oxalocrotonate Tautomerase
ABED_RS03965	COG0583	DNA-binding transcription factor activity
ABED_RS03970	COG0134	indole-3-glycerol-phosphate synthase activity
ABED_RS03980	COG0727	PFAM Uncharacterised protein family (UPF0153)
ABED_RS03985	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ABED_RS03995	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ABED_RS03995	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABED_RS04000	COG1013	pyruvate-flavodoxin oxidoreductase activity
ABED_RS04010	COG2176	DNA-directed DNA polymerase activity
ABED_RS04015	COG0135	phosphoribosylanthranilate isomerase activity
ABED_RS04020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABED_RS04040	COG1666	GTP binding
ABED_RS04050	COG2363	Small membrane protein
ABED_RS04055	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ABED_RS04070	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ABED_RS04160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ABED_RS04195	COG3550	peptidyl-serine autophosphorylation
ABED_RS04205	COG0840	transmembrane signaling receptor activity
ABED_RS04210	COG0840	transmembrane signaling receptor activity
ABED_RS04215	COG0840	transmembrane signaling receptor activity
ABED_RS04225	COG0750	zinc metalloprotease
ABED_RS04230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABED_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
ABED_RS04240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABED_RS04250	COG0167	dihydroorotate dehydrogenase activity
ABED_RS04255	COG1132	(ABC) transporter
ABED_RS04260	COG0728	peptidoglycan biosynthetic process
ABED_RS04275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABED_RS04285	COG3340	Belongs to the peptidase S51 family
ABED_RS04290	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ABED_RS04295	COG3150	esterase
ABED_RS04300	COG1858	cytochrome C peroxidase
ABED_RS04315	COG0552	protein localization to endoplasmic reticulum
ABED_RS04320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABED_RS04325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ABED_RS04330	COG1418	mRNA catabolic process
ABED_RS04335	COG0742	ribosomal rna small subunit methyltransferase
ABED_RS04340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABED_RS04345	COG0300	oxidoreductase activity
ABED_RS04360	COG3258	Cytochrome c
ABED_RS04370	COG0745	RESPONSE REGULATOR receiver
ABED_RS04375	COG0642	Histidine kinase
ABED_RS04380	COG0157	Belongs to the NadC ModD family
ABED_RS04390	COG1610	YqeY-like protein
ABED_RS04395	COG0488	(ABC) transporter
ABED_RS04405	COG0492	ferredoxin-NADP+ reductase activity
ABED_RS04410	COG0596	Alpha beta hydrolase
ABED_RS04425	COG0251	oxidation-reduction process
ABED_RS04450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABED_RS04450	COG0519	Catalyzes the synthesis of GMP from XMP
ABED_RS04455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ABED_RS04465	COG1451	nucleotide metabolic process
ABED_RS04470	COG0436	Aminotransferase
ABED_RS04475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABED_RS04510	COG1696	Membrane protein involved in D-alanine export
ABED_RS04520	COG2223	nitrite transmembrane transporter activity
ABED_RS04530	COG0310	cobalt ion transport
ABED_RS04555	COG3210	domain, Protein
ABED_RS04555	COG3210	domain, Protein
ABED_RS04590	COG0515	serine threonine protein kinase
ABED_RS04590	COG2815	serine threonine protein kinase
ABED_RS04600	COG0628	permease
ABED_RS04625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABED_RS04635	COG0840	transmembrane signaling receptor activity
ABED_RS04640	COG0730	response to heat
ABED_RS04645	COG1045	serine acetyltransferase
ABED_RS04650	COG1166	arginine decarboxylase activity
ABED_RS04655	COG0124	histidyl-tRNA synthetase
ABED_RS04660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABED_RS04665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABED_RS04670	COG0163	prenyltransferase activity
ABED_RS04680	COG0359	binds to the 23S rRNA
ABED_RS04685	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABED_RS04690	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABED_RS04700	COG0084	hydrolase, TatD family'
ABED_RS04710	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ABED_RS04715	COG0131	Imidazoleglycerol-phosphate dehydratase
ABED_RS04720	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABED_RS04735	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABED_RS04740	COG0456	acetyltransferase
ABED_RS04760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABED_RS04765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABED_RS04790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABED_RS04800	COG0784	Response regulator, receiver
ABED_RS04800	COG3437	response regulator, receiver
ABED_RS04810	COG0768	penicillin binding
ABED_RS04830	COG2884	Cell division ATP-binding protein ftsE
ABED_RS04835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABED_RS04845	COG0564	pseudouridine synthase activity
ABED_RS04850	COG0772	Belongs to the SEDS family
ABED_RS04860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABED_RS04865	COG3123	guanosine phosphorylase activity
ABED_RS04885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABED_RS04890	COG0066	3-isopropylmalate dehydratase activity
ABED_RS04895	COG0473	3-isopropylmalate dehydrogenase activity
ABED_RS04910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABED_RS04915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABED_RS04920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABED_RS04925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABED_RS04930	COG0202	RNA polymerase activity
ABED_RS04935	COG0203	ribosomal protein L17
ABED_RS04940	COG0154	amidase activity
ABED_RS04945	COG0516	GMP reductase activity
ABED_RS04945	COG0517	IMP dehydrogenase activity
ABED_RS04995	COG0484	heat shock protein binding
ABED_RS05010	COG3290	protein histidine kinase activity
ABED_RS05015	COG2205	protein histidine kinase activity
ABED_RS05015	COG0784	Response regulator, receiver
ABED_RS05035	COG1119	ATPase activity
ABED_RS05070	COG1733	regulation of RNA biosynthetic process
ABED_RS05075	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABED_RS05085	COG2076	Multidrug Resistance protein
ABED_RS05100	COG1881	PFAM PEBP family protein
ABED_RS05105	COG0583	DNA-binding transcription factor activity
ABED_RS05110	COG2855	membrane
ABED_RS05140	COG1733	regulation of RNA biosynthetic process
ABED_RS05145	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABED_RS05165	COG0778	Nitroreductase
ABED_RS05175	COG0488	(ABC) transporter
ABED_RS05180	COG1607	acyl-coa hydrolase
ABED_RS05185	COG0840	transmembrane signaling receptor activity
ABED_RS05190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABED_RS05195	COG0754	glutathionylspermidine amidase activity
ABED_RS05210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABED_RS05220	COG1496	oxidoreductase activity
ABED_RS05225	COG0281	malic enzyme
ABED_RS05225	COG0280	phosphate acetyltransferase
ABED_RS05230	COG0788	formyltetrahydrofolate deformylase activity
ABED_RS05235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ABED_RS05260	COG0745	RESPONSE REGULATOR receiver
ABED_RS05270	COG0330	HflC and HflK could
ABED_RS05295	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ABED_RS05305	COG0546	phosphoglycolate phosphatase activity
ABED_RS05325	COG4206	TonB-dependent receptor
ABED_RS05335	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABED_RS05340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABED_RS05345	COG0475	glutathione-regulated potassium exporter activity
ABED_RS05350	COG0406	alpha-ribazole phosphatase activity
ABED_RS05355	COG1132	(ABC) transporter
ABED_RS05365	COG0745	RESPONSE REGULATOR receiver
ABED_RS05370	COG0642	Histidine kinase
ABED_RS05405	COG0513	Belongs to the DEAD box helicase family
ABED_RS05415	COG0745	RESPONSE REGULATOR receiver
ABED_RS05450	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABED_RS05460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABED_RS05465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABED_RS05475	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABED_RS05480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABED_RS05525	COG0243	molybdopterin cofactor binding
ABED_RS05540	COG1193	negative regulation of DNA recombination
ABED_RS05545	COG1253	flavin adenine dinucleotide binding
ABED_RS05555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABED_RS05560	COG0004	ammonium transporteR
ABED_RS05585	COG0028	Belongs to the TPP enzyme family
ABED_RS05590	COG0440	acetolactate synthase activity
ABED_RS05595	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABED_RS05600	COG1674	ftsk spoiiie
ABED_RS05600	COG1196	nuclear chromosome segregation
ABED_RS05610	COG0642	Histidine kinase
ABED_RS05615	COG3012	SEC-C Motif Domain Protein
ABED_RS05625	COG1160	GTP binding
ABED_RS05630	COG0659	secondary active sulfate transmembrane transporter activity
ABED_RS05650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABED_RS05660	COG1185	polyribonucleotide nucleotidyltransferase activity
ABED_RS05670	COG2198	Histidine kinase
ABED_RS05670	COG0643	Histidine kinase
ABED_RS05675	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABED_RS05680	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABED_RS05685	COG2201	protein-glutamate methylesterase activity
ABED_RS05695	COG2223	nitrite transmembrane transporter activity
ABED_RS05700	COG0582	viral genome integration into host DNA
ABED_RS05720	COG0339	signal peptide processing
ABED_RS05725	COG2890	protein-(glutamine-N5) methyltransferase activity
ABED_RS05730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABED_RS05735	COG0494	nUDIX hydrolase
ABED_RS05740	COG0527	aspartate kinase activity
ABED_RS05755	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABED_RS05760	COG0287	Prephenate dehydrogenase
ABED_RS05765	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABED_RS05770	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABED_RS05775	COG0612	Peptidase, M16
ABED_RS05780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABED_RS05805	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ABED_RS05815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABED_RS05815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABED_RS05840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ABED_RS05865	COG0751	glycine-tRNA ligase activity
ABED_RS05880	COG0357	Ribosomal RNA small subunit methyltransferase G
ABED_RS05885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABED_RS05890	COG0113	porphobilinogen synthase activity
ABED_RS05895	COG0784	Response regulator, receiver
ABED_RS05895	COG4191	Histidine kinase
ABED_RS05900	COG0745	RESPONSE REGULATOR receiver
ABED_RS05910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABED_RS05910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABED_RS05915	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABED_RS05920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABED_RS05935	COG1663	tetraacyldisaccharide 4'-kinase activity
ABED_RS05945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABED_RS05970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABED_RS05975	COG0805	protein transport
ABED_RS05980	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABED_RS05985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABED_RS06000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ABED_RS06020	COG0247	lactate metabolic process
ABED_RS06020	COG2181	nitrate reductase activity
ABED_RS06025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABED_RS06050	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABED_RS06055	COG2200	EAL domain
ABED_RS06055	COG3287	FIST C domain
ABED_RS06055	COG2199	diguanylate cyclase activity
ABED_RS06060	COG1137	ATPase activity
ABED_RS06065	COG0802	atpase or kinase
ABED_RS06070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABED_RS06085	COG0137	argininosuccinate synthase activity
ABED_RS06090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABED_RS06095	COG1696	Membrane protein involved in D-alanine export
ABED_RS06105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABED_RS06115	COG0569	domain protein
ABED_RS06120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABED_RS06125	COG0745	RESPONSE REGULATOR receiver
ABED_RS06130	COG2205	protein histidine kinase activity
ABED_RS06145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABED_RS06150	COG0484	heat shock protein binding
ABED_RS06155	COG0133	tryptophan synthase activity
ABED_RS06175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABED_RS06185	COG2199	diguanylate cyclase activity
ABED_RS06190	COG0500	methyltransferase
ABED_RS06200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABED_RS06200	COG1333	cytochrome c biogenesis protein
ABED_RS06205	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABED_RS06215	COG0840	transmembrane signaling receptor activity
ABED_RS06225	COG0653	protein targeting
ABED_RS06230	COG4591	ABC-type transport system involved in lipoprotein release permease component
ABED_RS06240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABED_RS06250	COG0039	L-malate dehydrogenase activity
ABED_RS06275	COG0275	rRNA processing
ABED_RS06285	COG0776	regulation of translation
ABED_RS06405	COG2026	Addiction module toxin, RelE StbE family
ABED_RS06415	COG4974	Belongs to the 'phage' integrase family
ABED_RS06420	COG1959	2 iron, 2 sulfur cluster binding
ABED_RS06435	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ABED_RS06435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABED_RS06445	COG2201	protein-glutamate methylesterase activity
ABED_RS06460	COG0484	heat shock protein binding
ABED_RS06465	COG0789	Transcriptional regulator
ABED_RS06470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABED_RS06475	COG1131	(ABC) transporter
ABED_RS06480	COG0842	Transport permease protein
ABED_RS06485	COG0842	Transport permease protein
ABED_RS06490	COG0861	Integral membrane protein TerC family
ABED_RS06495	COG1114	Component of the transport system for branched-chain amino acids
ABED_RS06515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABED_RS06525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABED_RS06535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABED_RS06540	COG4773	Receptor
ABED_RS06550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABED_RS06595	COG0488	(ABC) transporter
ABED_RS06605	COG2171	N-acyltransferase activity
ABED_RS06610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABED_RS06620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABED_RS06650	COG0309	Hydrogenase expression formation protein (HypE)
ABED_RS06660	COG2084	Dehydrogenase
ABED_RS06670	COG0409	Hydrogenase expression formation protein
ABED_RS06675	COG0298	carbon dioxide binding
ABED_RS06680	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABED_RS06690	COG0840	transmembrane signaling receptor activity
ABED_RS06700	COG2081	HI0933 family
ABED_RS06705	COG2354	Protein conserved in bacteria
ABED_RS06720	COG2814	Major facilitator Superfamily
ABED_RS06730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABED_RS06730	COG0301	tRNA thio-modification
ABED_RS06750	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABED_RS06755	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABED_RS06760	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ABED_RS06765	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ABED_RS06770	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ABED_RS06775	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ABED_RS06790	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABED_RS06805	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ABED_RS06810	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ABED_RS06830	COG1049	propionate catabolic process, 2-methylcitrate cycle
ABED_RS06840	COG3706	GGDEF domain
ABED_RS06840	COG4251	negative regulation of phosphorylation
ABED_RS06840	COG2203	Gaf domain
ABED_RS06840	COG5001	Diguanylate cyclase
ABED_RS06845	COG0217	transcriptional regulatory protein
ABED_RS06850	COG2853	Lipoprotein
ABED_RS06865	COG1611	Belongs to the LOG family
ABED_RS06870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABED_RS06885	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABED_RS06905	COG4774	siderophore transport
ABED_RS06935	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABED_RS06960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABED_RS06965	COG2258	MOSC domain
ABED_RS06970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABED_RS06975	COG0095	Lipoate-protein ligase
ABED_RS06980	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ABED_RS06985	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABED_RS06990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABED_RS06995	COG1492	cobalamin metabolic process
ABED_RS07015	COG0513	Belongs to the DEAD box helicase family
ABED_RS07020	COG1944	ATP diphosphatase activity
ABED_RS07035	COG0840	transmembrane signaling receptor activity
ABED_RS07040	COG0328	RNA-DNA hybrid ribonuclease activity
ABED_RS07045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABED_RS07070	COG1104	cysteine desulfurase activity
ABED_RS07075	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ABED_RS07085	COG0437	4 iron, 4 sulfur cluster binding
ABED_RS07090	COG3383	formate dehydrogenase (NAD+) activity
ABED_RS07095	COG0243	molybdopterin cofactor binding
ABED_RS07095	COG3383	formate dehydrogenase (NAD+) activity
ABED_RS07145	COG1305	Transglutaminase-like
ABED_RS07155	COG0437	4 iron, 4 sulfur cluster binding
ABED_RS07160	COG0243	molybdopterin cofactor binding
ABED_RS07160	COG3383	formate dehydrogenase (NAD+) activity
ABED_RS07170	COG0709	Synthesizes selenophosphate from selenide and ATP
ABED_RS07225	COG1921	L-seryl-tRNASec selenium transferase activity
ABED_RS07290	COG1078	dGTPase activity
ABED_RS07295	COG5001	Diguanylate cyclase
ABED_RS07295	COG5002	protein histidine kinase activity
ABED_RS07300	COG0259	pyridoxamine-phosphate oxidase activity
ABED_RS07310	COG0513	Belongs to the DEAD box helicase family
ABED_RS07330	COG0326	Molecular chaperone. Has ATPase activity
ABED_RS07335	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ABED_RS07355	COG2995	paraquat-inducible protein a
ABED_RS07370	COG5002	protein histidine kinase activity
ABED_RS07370	COG5001	Diguanylate cyclase
ABED_RS07400	COG4335	DNA alkylation repair
ABED_RS07405	COG2329	Antibiotic biosynthesis monooxygenase
ABED_RS07425	COG4774	siderophore transport
ABED_RS07435	COG1595	DNA-templated transcription, initiation
ABED_RS07440	COG0010	Belongs to the arginase family
ABED_RS07445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABED_RS07455	COG0519	Catalyzes the synthesis of GMP from XMP
ABED_RS07460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABED_RS07465	COG0668	transmembrane transport
ABED_RS07470	COG1227	inorganic diphosphatase activity
ABED_RS07485	COG1027	Aspartate ammonia-lyase
ABED_RS07490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABED_RS07495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABED_RS07500	COG1047	Peptidyl-prolyl cis-trans
ABED_RS07515	COG0823	Involved in the tonB-independent uptake of proteins
ABED_RS07525	COG0848	biopolymer transport protein
ABED_RS07530	COG0811	peptide transport
ABED_RS07535	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABED_RS07540	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABED_RS07545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABED_RS07550	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABED_RS07555	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABED_RS07560	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABED_RS07570	COG1475	DNA binding
ABED_RS07575	COG1192	Involved in chromosome partitioning
ABED_RS07590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABED_RS07595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABED_RS07600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABED_RS07605	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABED_RS07610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABED_RS07615	COG0358	DNA primase activity
ABED_RS07625	COG0571	ribonuclease III activity
ABED_RS07630	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABED_RS07640	COG0501	Belongs to the peptidase M48B family
ABED_RS07660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABED_RS07670	COG0706	membrane insertase activity
ABED_RS07675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABED_RS07685	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ABED_RS07690	COG0542	response to heat
ABED_RS07695	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABED_RS07705	COG2326	polyphosphate kinase activity
ABED_RS07715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABED_RS07720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABED_RS07725	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABED_RS07750	COG0138	bifunctional purine biosynthesis protein purh
ABED_RS07755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABED_RS07765	COG0739	heme binding
ABED_RS07770	COG0302	gtp cyclohydrolase
ABED_RS07775	COG0598	Magnesium transport protein CorA
ABED_RS07800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABED_RS07810	COG0606	chelatase, subunit chli
ABED_RS07835	COG0210	DNA helicase
ABED_RS07885	COG0606	chelatase, subunit chli
ABED_RS07890	COG0840	transmembrane signaling receptor activity
ABED_RS07905	COG0242	peptide deformylase activity
ABED_RS07910	COG0740	serine-type endopeptidase activity
ABED_RS07915	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABED_RS07950	COG0626	cystathionine gamma-synthase activity
ABED_RS07965	COG0840	transmembrane signaling receptor activity
ABED_RS07975	COG0784	Response regulator, receiver
ABED_RS07975	COG3437	response regulator, receiver
ABED_RS07980	COG0840	transmembrane signaling receptor activity
ABED_RS07985	COG2205	protein histidine kinase activity
ABED_RS08015	COG0745	RESPONSE REGULATOR receiver
ABED_RS08025	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ABED_RS08040	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABED_RS08045	COG1858	cytochrome C peroxidase
ABED_RS08075	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABED_RS08100	COG0351	phosphomethylpyrimidine kinase
ABED_RS08105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABED_RS08120	COG0348	domain, Protein
ABED_RS08130	COG2207	Transcriptional regulator
ABED_RS08130	COG4753	response regulator
ABED_RS08145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABED_RS08165	COG0716	FMN binding
ABED_RS08180	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ABED_RS08185	COG0159	tryptophan synthase activity
ABED_RS08190	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABED_RS08195	COG2255	four-way junction helicase activity
ABED_RS08200	COG0628	permease
ABED_RS08240	COG0731	radical SAM domain protein
ABED_RS08245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABED_RS08255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABED_RS08270	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABED_RS08280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABED_RS08300	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABED_RS08300	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ABED_RS08305	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ABED_RS08310	COG1368	sulfuric ester hydrolase activity
ABED_RS08315	COG0859	PFAM glycosyl transferase family 9
ABED_RS08325	COG0859	PFAM glycosyl transferase family 9
ABED_RS08330	COG0463	Glycosyl transferase, family 2
ABED_RS08345	COG0438	transferase activity, transferring glycosyl groups
ABED_RS08365	COG1696	Membrane protein involved in D-alanine export
ABED_RS08375	COG1696	Membrane protein involved in D-alanine export
ABED_RS08385	COG1696	Membrane protein involved in D-alanine export
ABED_RS08440	COG0859	PFAM glycosyl transferase family 9
ABED_RS08450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABED_RS08460	COG0493	'glutamate synthase
ABED_RS08465	COG0067	glutamate synthase
ABED_RS08465	COG0069	glutamate synthase activity
ABED_RS08465	COG0070	glutamate synthase
ABED_RS08480	COG0840	transmembrane signaling receptor activity
ABED_RS08485	COG0840	transmembrane signaling receptor activity
ABED_RS08495	COG1739	Uncharacterized protein family UPF0029
ABED_RS08505	COG0196	riboflavin kinase activity
ABED_RS08510	COG2226	methyltransferase
ABED_RS08515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABED_RS08525	COG0277	FAD linked oxidase domain protein
ABED_RS08530	COG1295	ribonuclease BN
ABED_RS08540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABED_RS08550	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ABED_RS08555	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABED_RS08560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABED_RS08565	COG0284	orotidine-5'-phosphate decarboxylase activity
ABED_RS08590	COG1918	ferrous iron import across plasma membrane
ABED_RS08595	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABED_RS08595	COG1918	ferrous iron import across plasma membrane
ABED_RS08620	COG2217	Heavy metal translocating P-type atpase
ABED_RS08630	COG4773	Receptor
ABED_RS08640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABED_RS08655	COG1278	Cold shock
ABED_RS08660	COG4753	response regulator
ABED_RS08660	COG2207	Transcriptional regulator
ABED_RS08665	COG3852	Histidine kinase
ABED_RS08695	COG3135	benzoate transporter
ABED_RS08710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABED_RS08715	COG0085	RNA polymerase activity
ABED_RS08720	COG0222	ribosome binding
ABED_RS08725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABED_RS08730	COG0081	regulation of translation
ABED_RS08735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABED_RS08740	COG0250	Participates in transcription elongation, termination and antitermination
ABED_RS08755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABED_RS08760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABED_RS08790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABED_RS08795	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ABED_RS08800	COG0444	Belongs to the ABC transporter superfamily
ABED_RS08805	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ABED_RS08810	COG0174	glutamine synthetase
ABED_RS08820	COG0314	molybdopterin synthase activity
ABED_RS08830	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ABED_RS08835	COG1968	undecaprenyl-diphosphatase activity
ABED_RS08840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABED_RS08845	COG0772	Belongs to the SEDS family
ABED_RS08855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABED_RS08895	COG0542	response to heat
ABED_RS08900	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABED_RS08905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ABED_RS08920	COG2030	dehydratase
ABED_RS08940	COG0840	transmembrane signaling receptor activity
ABED_RS08945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABED_RS08965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABED_RS08970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABED_RS08980	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABED_RS08985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABED_RS08990	COG1157	protein secretion by the type III secretion system
ABED_RS09000	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABED_RS09020	COG1677	Flagellar hook-basal body complex protein FliE
ABED_RS09030	COG0455	bacterial-type flagellum organization
ABED_RS09035	COG1419	protein localization to endoplasmic reticulum
ABED_RS09050	COG3951	Flagellar rod assembly protein muramidase FlgJ
ABED_RS09075	COG1749	Flagellar hook protein flgE
ABED_RS09090	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABED_RS09100	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABED_RS09105	COG1766	The M ring may be actively involved in energy transduction
ABED_RS09110	COG1815	bacterial-type flagellum-dependent cell motility
ABED_RS09115	COG4786	Flagellar basal body rod
ABED_RS09125	COG0745	RESPONSE REGULATOR receiver
ABED_RS09130	COG4786	Flagellar basal body rod
ABED_RS09145	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABED_RS09155	COG0228	four-way junction DNA binding
ABED_RS09160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABED_RS09165	COG0564	pseudouridine synthase activity
ABED_RS09170	COG1519	Transferase
ABED_RS09180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABED_RS09185	COG0752	glycyl-tRNA synthetase alpha subunit
ABED_RS09195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABED_RS09205	COG0826	peptidase U32
ABED_RS09210	COG0840	transmembrane signaling receptor activity
ABED_RS09215	COG0497	DNA recombination
ABED_RS09220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABED_RS09225	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABED_RS09230	COG0049	tRNA binding
ABED_RS09235	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABED_RS09245	COG2814	Major facilitator Superfamily
ABED_RS09250	COG4771	TonB-dependent receptor
ABED_RS09265	COG1116	anion transmembrane transporter activity
ABED_RS09270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABED_RS09310	COG0512	Glutamine amidotransferase of anthranilate synthase
ABED_RS09315	COG1309	transcriptional regulator
ABED_RS09320	COG4221	oxidoreductase activity
ABED_RS09330	COG1840	ABC-type Fe3 transport system, periplasmic component
ABED_RS09335	COG1178	ABC-type Fe3 transport system permease component
ABED_RS09350	COG4774	siderophore transport
ABED_RS09390	COG2183	response to ionizing radiation
ABED_RS09400	COG0251	oxidation-reduction process
ABED_RS09415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABED_RS09425	COG0586	Pfam SNARE associated Golgi protein
ABED_RS09430	COG0335	large ribosomal subunit rRNA binding
ABED_RS09435	COG0336	Belongs to the RNA methyltransferase TrmD family
ABED_RS09445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABED_RS09450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABED_RS09455	COG0356	it plays a direct role in the translocation of protons across the membrane
ABED_RS09465	COG4773	Receptor
ABED_RS09475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABED_RS09485	COG0157	Belongs to the NadC ModD family
ABED_RS09500	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ABED_RS09510	COG0083	homoserine kinase activity
ABED_RS09520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABED_RS09525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABED_RS09530	COG0779	Required for maturation of 30S ribosomal subunits
ABED_RS09535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABED_RS09535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABED_RS09540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABED_RS09545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABED_RS09550	COG0539	negative regulation of cytoplasmic translation
ABED_RS09550	COG1185	polyribonucleotide nucleotidyltransferase activity
ABED_RS09555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABED_RS09560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABED_RS09565	COG0072	phenylalanine-tRNA ligase activity
ABED_RS09565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABED_RS09570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABED_RS09575	COG0537	adenosine 5'-monophosphoramidase activity
ABED_RS09580	COG0825	malonyl-CoA metabolic process
ABED_RS09585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABED_RS09590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABED_RS09600	COG0602	queuosine metabolic process
ABED_RS09610	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABED_RS09620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABED_RS09630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABED_RS09640	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABED_RS09645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABED_RS09650	COG1074	ATP-dependent DNA helicase activity
ABED_RS09660	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ABED_RS09705	COG3278	Belongs to the heme-copper respiratory oxidase family
ABED_RS09710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABED_RS09715	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABED_RS09720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABED_RS09735	COG1242	4 iron, 4 sulfur cluster binding
ABED_RS09740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ABED_RS09745	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABED_RS09750	COG0492	ferredoxin-NADP+ reductase activity
ABED_RS09755	COG3118	belongs to the thioredoxin family
ABED_RS09760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABED_RS09785	COG0642	Histidine kinase
ABED_RS09790	COG0745	RESPONSE REGULATOR receiver
ABED_RS09800	COG0129	dihydroxy-acid dehydratase activity
ABED_RS09830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABED_RS09845	COG0585	pseudouridine synthase activity
ABED_RS09860	COG0793	Belongs to the peptidase S41A family
ABED_RS09865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABED_RS09870	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABED_RS09875	COG0047	phosphoribosylformylglycinamidine synthase activity
ABED_RS09885	COG0204	Acyl-transferase
ABED_RS09890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABED_RS09895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABED_RS09900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABED_RS09905	COG0018	arginyl-trna synthetase
ABED_RS09915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABED_RS09925	COG0126	phosphoglycerate kinase activity
ABED_RS09930	COG0149	triose-phosphate isomerase activity
ABED_RS09935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ABED_RS09940	COG0019	diaminopimelate decarboxylase activity
ABED_RS09945	COG0077	Prephenate dehydratase
ABED_RS09945	COG1605	Chorismate mutase
ABED_RS09950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABED_RS09955	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABED_RS09965	COG0424	maF-like protein
ABED_RS09980	COG0791	NLP P60 protein
ABED_RS09995	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABED_RS10000	COG1012	belongs to the aldehyde dehydrogenase family
ABED_RS10010	COG1704	LemA family
ABED_RS10025	COG0546	phosphoglycolate phosphatase activity
ABED_RS10030	COG0783	Belongs to the Dps family
ABED_RS10045	COG2814	Major facilitator Superfamily
ABED_RS10060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABED_RS10065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABED_RS10085	COG1595	DNA-templated transcription, initiation
ABED_RS10095	COG2081	HI0933 family
ABED_RS10110	COG1959	2 iron, 2 sulfur cluster binding
ABED_RS10125	COG0175	sulfate reduction
ABED_RS10130	COG0175	sulfate reduction
ABED_RS10135	COG2895	sulfate adenylyltransferase (ATP) activity
ABED_RS10150	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABED_RS10180	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ABED_RS10195	COG4232	protein-disulfide reductase activity
ABED_RS10200	COG0189	ligase activity
ABED_RS10215	COG2200	EAL domain
ABED_RS10215	COG3287	FIST C domain
ABED_RS10215	COG2199	diguanylate cyclase activity
ABED_RS10220	COG0688	phosphatidylethanolamine metabolic process
ABED_RS10230	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ABED_RS10235	COG0443	Heat shock 70 kDa protein
ABED_RS10240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABED_RS10255	COG0101	tRNA pseudouridine synthase activity
ABED_RS10270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABED_RS10275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABED_RS10280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABED_RS10295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABED_RS10300	COG0494	nUDIX hydrolase
ABED_RS10315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABED_RS10390	COG0445	tRNA wobble uridine modification
ABED_RS10410	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABED_RS10415	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABED_RS10420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABED_RS10425	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABED_RS10430	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABED_RS10440	COG1252	NADH dehydrogenase
ABED_RS10445	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ABED_RS10455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABED_RS10470	COG2814	Major facilitator Superfamily
ABED_RS10475	COG0659	secondary active sulfate transmembrane transporter activity
ABED_RS10495	COG1222	aaa ATPase
ABED_RS10505	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ABED_RS10510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ABED_RS10525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABED_RS10540	COG0148	phosphopyruvate hydratase activity
ABED_RS10545	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABED_RS10555	COG1086	Polysaccharide biosynthesis protein
ABED_RS10560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABED_RS10565	COG1083	cytidylyl-transferase
ABED_RS10570	COG2089	acid synthase
ABED_RS10590	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABED_RS10610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABED_RS10620	COG0348	domain, Protein
ABED_RS10625	COG0504	CTP synthase activity
ABED_RS10630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABED_RS10655	COG0587	DNA-directed DNA polymerase activity
ABED_RS10660	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABED_RS10675	COG0315	cyclic pyranopterin monophosphate synthase activity
ABED_RS10680	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABED_RS10710	COG0670	Belongs to the BI1 family
ABED_RS10715	COG0352	thiamine-phosphate diphosphorylase activity
ABED_RS10725	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABED_RS10730	COG0233	cytoplasmic translational termination
ABED_RS10735	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABED_RS10755	COG3022	response to hydroperoxide
ABED_RS10790	COG3022	response to hydroperoxide
ABED_RS10810	COG3022	response to hydroperoxide
ABED_RS10825	COG1408	metallophosphoesterase
ABED_RS10830	COG0071	Belongs to the small heat shock protein (HSP20) family
ABED_RS10835	COG2703	oxygen carrier activity
ABED_RS10855	COG2308	Evidence 4 Homologs of previously reported genes of
ABED_RS10860	COG1305	Transglutaminase-like
ABED_RS10870	COG4208	sulfate ABC transporter
ABED_RS10875	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ABED_RS10885	COG3287	FIST C domain
ABED_RS10885	COG2199	diguanylate cyclase activity
ABED_RS10885	COG2200	EAL domain
ABED_RS10900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABED_RS10910	COG1116	anion transmembrane transporter activity
ABED_RS10920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABED_RS10925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABED_RS10935	COG1116	anion transmembrane transporter activity
ABED_RS10940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABED_RS10945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABED_RS10950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABED_RS10975	COG2308	Evidence 4 Homologs of previously reported genes of
ABED_RS10980	COG1217	gtp-binding protein TYPA
ABED_RS10985	COG2391	methyltransferase activity
ABED_RS10990	COG0425	Belongs to the sulfur carrier protein TusA family
ABED_RS11025	COG3706	GGDEF domain
ABED_RS11070	COG0745	RESPONSE REGULATOR receiver
ABED_RS11075	COG0642	Histidine kinase
ABED_RS11080	COG2226	methyltransferase
ABED_RS11085	COG2207	Transcriptional regulator
ABED_RS11090	COG0784	Response regulator, receiver
ABED_RS11090	COG3437	response regulator, receiver
ABED_RS11095	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ABED_RS11115	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group