locus-tag	class	description
ACLO_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ACLO_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
ACLO_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACLO_RS00020	ENOG4105CAY	ferredoxin--nadp reductase
ACLO_RS00025	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
ACLO_RS00035	ENOG4105W39	Membrane
ACLO_RS00040	ENOG4105CBP	Major Facilitator
ACLO_RS00045	ENOG4105EI2	Pseudouridine synthase
ACLO_RS00050	ENOG4107QTF	adenylosuccinate lyase
ACLO_RS00055	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACLO_RS00060	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACLO_RS00070	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
ACLO_RS00090	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
ACLO_RS00100	ENOG4105BZ8	glutamate synthase
ACLO_RS00110	ENOG4105CE9	30S ribosomal protein S2
ACLO_RS00125	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ACLO_RS00130	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ACLO_RS00135	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
ACLO_RS00150	ENOG4105BZU	Histidine kinase
ACLO_RS00155	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
ACLO_RS00160	ENOG4107QR9	Iron-sulfur cluster binding protein
ACLO_RS00165	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
ACLO_RS00175	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ACLO_RS00180	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ACLO_RS00185	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ACLO_RS00190	ENOG4105C1J	atp-dependent rna helicase
ACLO_RS00195	ENOG4105CJ3	phosphate transporter
ACLO_RS00205	ENOG4105CAQ	asparagine synthetase
ACLO_RS00215	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
ACLO_RS00235	ENOG4108IAB	Phoh family
ACLO_RS00240	ENOG4108YXA	Membrane
ACLO_RS00245	ENOG4105D1H	recombination factor protein RarA
ACLO_RS00250	ENOG4105FE9	pseudouridine synthase
ACLO_RS00255	ENOG4105C2X	Arabinose 5-phosphate isomerase
ACLO_RS00265	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ACLO_RS00270	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ACLO_RS00285	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ACLO_RS00290	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ACLO_RS00295	ENOG4105VFU	Rna-binding protein
ACLO_RS00310	ENOG4105BZU	Histidine kinase
ACLO_RS00330	ENOG4108IJF	Heavy metal efflux pump, CzcA
ACLO_RS00335	ENOG4108YYC	ycei family
ACLO_RS00350	ENOG4105D6E	homoserine dehydrogenase
ACLO_RS00355	ENOG4105CHM	Aminotransferase
ACLO_RS00375	ENOG41082DI	50s ribosomal protein l31
ACLO_RS00380	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
ACLO_RS00490	ENOG4107QHF	type ii secretion system protein e
ACLO_RS00495	ENOG4107QHF	type ii secretion system protein e
ACLO_RS00525	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
ACLO_RS00530	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
ACLO_RS00535	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
ACLO_RS00540	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
ACLO_RS00545	ENOG41084QV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
ACLO_RS00550	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
ACLO_RS00555	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ACLO_RS00560	ENOG4105C2I	pirin domain protein
ACLO_RS00565	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
ACLO_RS00575	ENOG41090MY	MarR family Transcriptional regulator
ACLO_RS00580	ENOG4107UUH	Aminotransferase
ACLO_RS00585	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
ACLO_RS00590	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ACLO_RS00600	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
ACLO_RS00615	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
ACLO_RS00630	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
ACLO_RS00635	ENOG4105D1F	ATP-binding protein
ACLO_RS00645	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ACLO_RS00655	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ACLO_RS00665	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
ACLO_RS00670	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS00685	ENOG4105D3R	alkyl hydroperoxide reductase
ACLO_RS00700	ENOG4108I6A	alcohol dehydrogenase
ACLO_RS00705	ENOG4105BZU	Histidine kinase
ACLO_RS00715	ENOG4105DZ1	carboxypeptidase
ACLO_RS00730	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
ACLO_RS00755	ENOG4105F3T	(LipO)protein
ACLO_RS00760	ENOG4105CY3	ABC transporter, permease
ACLO_RS00765	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
ACLO_RS00780	ENOG4108KK1	membrane protein AbrB duplication
ACLO_RS00785	ENOG4105KVH	Transcriptional regulator
ACLO_RS00790	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
ACLO_RS00795	ENOG4105DDK	oxidoreductase, beta subunit
ACLO_RS00800	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
ACLO_RS00810	ENOG4105EJ5	oxidoreductase gamma subunit
ACLO_RS00815	ENOG4107XGZ	Hydrolase
ACLO_RS00825	ENOG4108UJD	30S ribosomal protein S9
ACLO_RS00830	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
ACLO_RS00840	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ACLO_RS00850	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
ACLO_RS00855	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
ACLO_RS00860	ENOG4105E2Z	phosphate ABC transporter (Permease
ACLO_RS00865	ENOG4105C8U	phosphate abc transporter
ACLO_RS00870	ENOG4105PWN	phosphate abc transporter
ACLO_RS00880	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ACLO_RS00885	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
ACLO_RS00890	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
ACLO_RS00895	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ACLO_RS00900	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ACLO_RS00910	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
ACLO_RS00920	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ACLO_RS00925	ENOG41084M8	50s ribosomal protein L35
ACLO_RS00930	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ACLO_RS00960	ENOG4105KNE	Phosphatidate cytidylyltransferase
ACLO_RS00965	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
ACLO_RS00985	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ACLO_RS00990	ENOG4108ZJT	translation initiation factor, Sui1
ACLO_RS00995	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
ACLO_RS01000	ENOG4105VF7	tolerance protein
ACLO_RS01005	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ACLO_RS01045	ENOG4105D85	methylase
ACLO_RS01060	ENOG4107R3N	Filamentation induced by cAMP protein fic
ACLO_RS01065	ENOG4105F6A	helicase
ACLO_RS01070	ENOG4105ECI	YeeC-like protein
ACLO_RS01090	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ACLO_RS01100	ENOG4105MZU	cell filamentation protein
ACLO_RS01105	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
ACLO_RS01110	ENOG4108C33	Resolvase
ACLO_RS01120	ENOG4105KK4	UPF0060 membrane protein
ACLO_RS01125	ENOG4105C59	p-type ATPase
ACLO_RS01155	ENOG4105EKQ	RNA-directed DNA polymerase
ACLO_RS01160	ENOG4108C33	Resolvase
ACLO_RS01165	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACLO_RS01200	ENOG4105GR3	Histidine kinase
ACLO_RS01220	ENOG4105C59	p-type ATPase
ACLO_RS01240	ENOG4105E3B	Multicopper oxidase
ACLO_RS01260	ENOG4108JU5	Magnesium and cobalt efflux protein
ACLO_RS01265	ENOG4105DSF	transport protein
ACLO_RS01270	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ACLO_RS01285	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ACLO_RS01425	ENOG4108KU3	Integrase
ACLO_RS01445	ENOG4105D9Q	decarboxylase (Beta subunit)
ACLO_RS01450	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ACLO_RS01470	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS01490	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ACLO_RS01500	ENOG4108JJA	ABC, transporter
ACLO_RS01505	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
ACLO_RS01515	ENOG4105BZU	Histidine kinase
ACLO_RS01520	ENOG4105CV1	Transketolase (EC 2.2.1.1)
ACLO_RS01540	ENOG41067MG	lrgb family
ACLO_RS01550	ENOG4105KK4	UPF0060 membrane protein
ACLO_RS01565	ENOG4105CHH	sulfate transporter
ACLO_RS01570	ENOG4105BZU	Histidine kinase
ACLO_RS01575	ENOG4105BZU	Histidine kinase
ACLO_RS01595	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
ACLO_RS01605	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
ACLO_RS01625	ENOG4108YZA	Nitrogen regulatory protein pii
ACLO_RS01635	ENOG4108YZA	Nitrogen regulatory protein pii
ACLO_RS01640	ENOG4105EKE	dihydroorotase
ACLO_RS01645	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
ACLO_RS01650	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
ACLO_RS01660	ENOG4105VS8	Flagellar biosynthetic protein fliq
ACLO_RS01685	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
ACLO_RS01690	ENOG4105E1Q	flagellar hook-associated protein
ACLO_RS01695	ENOG4107W9T	flagellar hook-associated
ACLO_RS01715	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ACLO_RS01720	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
ACLO_RS01730	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
ACLO_RS01735	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
ACLO_RS01745	ENOG4105EAC	phosphoserine phosphatase
ACLO_RS01750	ENOG4107V25	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
ACLO_RS01755	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
ACLO_RS01760	ENOG4105DRB	nucleoside-specific channel-forming protein
ACLO_RS01765	ENOG4105KUZ	arsenate reductase
ACLO_RS01770	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ACLO_RS01775	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
ACLO_RS01785	ENOG4105CHM	Aminotransferase
ACLO_RS01795	ENOG4105DFU	Cell wall formation (By similarity)
ACLO_RS01805	ENOG4105PXI	polysaccharide deacetylase
ACLO_RS01810	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
ACLO_RS01815	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
ACLO_RS01820	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
ACLO_RS01830	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
ACLO_RS01835	ENOG4108UUM	single-stranded DNA-binding protein
ACLO_RS01840	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
ACLO_RS01850	ENOG4105C8N	cysteinyl-tRNA synthetase
ACLO_RS01855	ENOG4105CHV	Transcription elongation factor NusA
ACLO_RS01865	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ACLO_RS01870	ENOG4105KB8	(LipO)protein
ACLO_RS01880	ENOG4105DVY	radical SAM domain protein
ACLO_RS01895	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ACLO_RS01900	ENOG41082UM	UPF0102 protein
ACLO_RS01915	ENOG4105CDV	Ompa motb domain protein
ACLO_RS01920	ENOG4105CA9	Pyruvate kinase
ACLO_RS01935	ENOG4105C8Y	Acetylornithine aminotransferase
ACLO_RS01945	ENOG4105CXT	aspartate transcarbamylase
ACLO_RS01970	ENOG4108UMN	azlc family
ACLO_RS01975	ENOG4105KMT	branched-chain amino acid
ACLO_RS01980	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ACLO_RS01985	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
ACLO_RS01990	ENOG4105YQ2	50s ribosomal protein l32
ACLO_RS02000	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ACLO_RS02010	ENOG4105D3R	alkyl hydroperoxide reductase
ACLO_RS02015	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
ACLO_RS02020	ENOG4105D82	Glutamate dehydrogenase
ACLO_RS02025	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
ACLO_RS02030	ENOG4107QMP	dna polymerase iii subunits gamma and tau
ACLO_RS02040	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
ACLO_RS02050	ENOG4108K0B	C-di-gmp phosphodiesterase
ACLO_RS02055	ENOG4105C7F	AcnD-accessory protein PrpF
ACLO_RS02060	ENOG4108I0Z	Aconitate hydratase
ACLO_RS02065	ENOG4105BZN	citrate synthase
ACLO_RS02070	ENOG4105CR4	methylisocitrate lyase
ACLO_RS02080	ENOG4105C5I	Dehydrogenase
ACLO_RS02105	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ACLO_RS02110	ENOG4108BSC	Methyltransferase
ACLO_RS02125	ENOG4108VKG	metal-dependent hydrolase
ACLO_RS02140	ENOG4105E33	succinate dehydrogenase
ACLO_RS02145	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
ACLO_RS02150	ENOG4108S24	Fumarate reduCtase
ACLO_RS02155	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_RS02160	ENOG4105C8S	subunit m
ACLO_RS02165	ENOG4105D65	subunit l
ACLO_RS02170	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_RS02185	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ACLO_RS02190	ENOG4108IEH	NADH dehydrogenase subunit g
ACLO_RS02195	ENOG4105BZN	citrate synthase
ACLO_RS02210	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_RS02215	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_RS02220	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACLO_RS02225	ENOG4105C87	Aminotransferase class I and II
ACLO_RS02230	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ACLO_RS02235	ENOG4107XM3	UPF0442 protein
ACLO_RS02240	ENOG4105DWK	Membrane
ACLO_RS02250	ENOG4108VHG	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
ACLO_RS02255	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
ACLO_RS02270	ENOG4105BZU	Histidine kinase
ACLO_RS02290	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
ACLO_RS02305	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_RS02325	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ACLO_RS02330	ENOG4105GXZ	Ferredoxin-type protein NapH
ACLO_RS02335	ENOG4108BGM	Quinol dehydrogenase periplasmic component
ACLO_RS02340	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ACLO_RS02345	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ACLO_RS02350	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
ACLO_RS02355	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ACLO_RS02365	ENOG410812K	response regulator receiver protein
ACLO_RS02370	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ACLO_RS02375	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ACLO_RS02390	ENOG4107QYG	anthranilate phosphoribosyltransferase
ACLO_RS02395	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ACLO_RS02410	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
ACLO_RS02415	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
ACLO_RS02420	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ACLO_RS02425	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
ACLO_RS02430	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
ACLO_RS02440	ENOG4105DHQ	Histidine kinase
ACLO_RS02445	ENOG4105ETX	regulatoR
ACLO_RS02455	ENOG4105D2N	Aldolase
ACLO_RS02460	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACLO_RS02470	ENOG4105D38	putrescine abc transporter
ACLO_RS02475	ENOG4107RUE	extracellular solute-binding protein family 1
ACLO_RS02480	ENOG4105VEQ	Cold shock protein
ACLO_RS02485	ENOG4105SG9	biopolymer transport protein, ExbD
ACLO_RS02490	ENOG4105M8K	biopolymer transport protein
ACLO_RS02500	ENOG4105BZU	Histidine kinase
ACLO_RS02505	ENOG4105BZU	Histidine kinase
ACLO_RS02510	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ACLO_RS02515	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
ACLO_RS02525	ENOG4105EAH	synthase
ACLO_RS02530	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
ACLO_RS02535	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ACLO_RS02545	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ACLO_RS02565	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
ACLO_RS02570	ENOG4105VIE	preprotein translocase, subunit YajC
ACLO_RS02575	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACLO_RS02580	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACLO_RS02590	ENOG4105C8T	Leucyl-tRNA synthetase
ACLO_RS02600	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ACLO_RS02675	ENOG4108JA2	transcriptioN-repair coupling factor
ACLO_RS02705	ENOG4105CBX	hi0933 family
ACLO_RS02710	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS02720	ENOG410903D	sensor protein
ACLO_RS02725	ENOG4108HWS	Histidine kinase
ACLO_RS02730	ENOG4105D48	metallophosphoesterase
ACLO_RS02745	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ACLO_RS02750	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ACLO_RS02755	ENOG4108V3W	Chemotaxis protein, CheW
ACLO_RS02765	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ACLO_RS02775	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
ACLO_RS02780	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
ACLO_RS02790	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ACLO_RS02795	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ACLO_RS02800	ENOG4105ECY	inositol monophosphatase
ACLO_RS02805	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ACLO_RS02820	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
ACLO_RS02825	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
ACLO_RS02830	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ACLO_RS02835	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
ACLO_RS02845	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ACLO_RS02850	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
ACLO_RS02855	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACLO_RS02860	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ACLO_RS02875	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ACLO_RS02890	ENOG4105KJM	monovalent cation h antiporter subunit g
ACLO_RS02910	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_RS02915	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ACLO_RS02920	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ACLO_RS02925	ENOG4105BZU	Histidine kinase
ACLO_RS02930	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
ACLO_RS02935	ENOG4105ECP	epimerase
ACLO_RS02940	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
ACLO_RS03000	ENOG4105CVR	type I restriction-modification system
ACLO_RS03005	ENOG41082EK	Restriction modification system DNA (Specificity
ACLO_RS03025	ENOG4105DZR	Type I site-specific deoxyribonuclease
ACLO_RS03060	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ACLO_RS03065	ENOG4105CDV	Ompa motb domain protein
ACLO_RS03070	ENOG4105CDV	Ompa motb domain protein
ACLO_RS03075	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ACLO_RS03090	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ACLO_RS03095	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ACLO_RS03100	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACLO_RS03105	ENOG4105DC7	peptidase M24
ACLO_RS03110	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ACLO_RS03115	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
ACLO_RS03130	ENOG4108IJ2	phosphate acetyltransferase
ACLO_RS03135	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ACLO_RS03145	ENOG4107S1V	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ACLO_RS03155	ENOG4107QN1	sodium solute
ACLO_RS03165	ENOG4107QN1	sodium solute
ACLO_RS03175	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
ACLO_RS03185	ENOG4107QN1	sodium solute
ACLO_RS03195	ENOG4108STX	response regulator
ACLO_RS03200	ENOG4105BZU	Histidine kinase
ACLO_RS03245	ENOG4105CEV	competence damage-inducible protein
ACLO_RS03250	ENOG4107RSR	Malate quinone oxidoreductase
ACLO_RS03255	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
ACLO_RS03270	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
ACLO_RS03295	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ACLO_RS03300	ENOG4105CE9	30S ribosomal protein S2
ACLO_RS03305	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ACLO_RS03320	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ACLO_RS03325	ENOG4105BZU	Histidine kinase
ACLO_RS03330	ENOG4105C59	p-type ATPase
ACLO_RS03345	ENOG4107H6U	ABC transporter
ACLO_RS03350	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ACLO_RS03355	ENOG4105NBF	ammecr1 domain protein
ACLO_RS03360	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
ACLO_RS03365	ENOG4107S90	membrAne
ACLO_RS03370	ENOG4105FDK	ABC transporter
ACLO_RS03395	ENOG4105QNR	S1 RNA binding domain protein
ACLO_RS03400	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
ACLO_RS03415	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
ACLO_RS03420	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
ACLO_RS03425	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
ACLO_RS03440	ENOG4105ENA	helicase
ACLO_RS03450	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
ACLO_RS03475	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
ACLO_RS03490	ENOG4105C7Z	Conserved Protein
ACLO_RS03540	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
ACLO_RS03550	ENOG4108UYN	gCN5-related N-acetyltransferase
ACLO_RS03565	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
ACLO_RS03570	ENOG4105BZS	acriflavin resistance protein
ACLO_RS03590	ENOG4106TD9	Diguanylate cyclase
ACLO_RS03600	ENOG4107RDB	Major Facilitator
ACLO_RS03605	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ACLO_RS03630	ENOG410901F	(LipO)protein
ACLO_RS03635	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ACLO_RS03685	ENOG4105CNG	UPF0061 protein
ACLO_RS03705	ENOG4105BZS	acriflavin resistance protein
ACLO_RS03715	ENOG4105KPY	Small multidrug resistance protein
ACLO_RS03725	ENOG4105BZU	Histidine kinase
ACLO_RS03735	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ACLO_RS03740	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_RS03745	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS03775	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
ACLO_RS03780	ENOG4105C9B	Cysteine desulfurase
ACLO_RS03790	ENOG4105C3K	feS assembly ATPase SufC
ACLO_RS03805	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
ACLO_RS03815	ENOG4105CJW	magnesium transporter
ACLO_RS03845	ENOG4105FQT	
ACLO_RS03850	ENOG4105CH7	arginosuccinase
ACLO_RS03860	ENOG4105CUZ	uba thif-type nad fad binding protein
ACLO_RS03865	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ACLO_RS03870	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
ACLO_RS03885	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
ACLO_RS03920	ENOG4108YZG	isomerase
ACLO_RS03925	ENOG4105C3F	Signal peptidase i
ACLO_RS03930	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ACLO_RS03935	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
ACLO_RS03940	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ACLO_RS03955	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
ACLO_RS03965	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ACLO_RS03975	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
ACLO_RS03980	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
ACLO_RS03990	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
ACLO_RS03995	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
ACLO_RS04000	ENOG4105CRQ	synthase (Component I)
ACLO_RS04010	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ACLO_RS04015	ENOG4105CRK	lysyL-tRNA synthetase
ACLO_RS04030	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
ACLO_RS04040	ENOG4105CDU	Replicative dna helicase
ACLO_RS04045	ENOG4108VAU	general secretion pathway protein G
ACLO_RS04055	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
ACLO_RS04060	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ACLO_RS04070	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ACLO_RS04080	ENOG4105M15	transport protein ExbD
ACLO_RS04085	ENOG4105M8K	biopolymer transport protein
ACLO_RS04100	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACLO_RS04105	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACLO_RS04125	ENOG4107S8A	protein TIM barrel
ACLO_RS04190	ENOG41090R7	Ferric uptake
ACLO_RS04205	ENOG4105CE1	Ferrous iron transport protein b
ACLO_RS04210	ENOG4105XFK	Ferrous iron transport protein A
ACLO_RS04230	ENOG4107F3C	Hemin uptake protein
ACLO_RS04235	ENOG4108IU3	tonb-dependent siderophore receptor
ACLO_RS04240	ENOG4107E2E	PKHD-type hydroxylase
ACLO_RS04250	ENOG4105D05	Receptor
ACLO_RS04265	ENOG4105BZU	Histidine kinase
ACLO_RS04275	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
ACLO_RS04280	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ACLO_RS04295	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
ACLO_RS04300	ENOG4105CPF	Cell wall formation (By similarity)
ACLO_RS04305	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
ACLO_RS04310	ENOG4105DFU	Cell wall formation (By similarity)
ACLO_RS04325	ENOG4107QMZ	Dehydrogenase
ACLO_RS04330	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
ACLO_RS04335	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ACLO_RS04340	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ACLO_RS04345	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
ACLO_RS04350	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACLO_RS04355	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ACLO_RS04360	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ACLO_RS04365	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ACLO_RS04370	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ACLO_RS04375	ENOG41084HJ	50s ribosomal protein l29
ACLO_RS04380	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ACLO_RS04385	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ACLO_RS04390	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ACLO_RS04395	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACLO_RS04400	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
ACLO_RS04405	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ACLO_RS04410	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ACLO_RS04415	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ACLO_RS04420	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ACLO_RS04425	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
ACLO_RS04430	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
ACLO_RS04435	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
ACLO_RS04440	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
ACLO_RS04450	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
ACLO_RS04460	ENOG4105C9M	aspartyl-trna synthetase
ACLO_RS04475	ENOG4105CCT	upf0313 protein
ACLO_RS04480	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ACLO_RS04485	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ACLO_RS04500	ENOG4105C32	Amino acid ABC transporter (Permease)
ACLO_RS04510	ENOG4105C0Z	ABC transporter
ACLO_RS04515	ENOG4108IV0	ABC, transporter
ACLO_RS04535	ENOG4108YZ9	Urea amidohydrolase subunit gamma
ACLO_RS04540	ENOG4105CQM	Urea amidohydrolase subunit alpha
ACLO_RS04555	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
ACLO_RS04565	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
ACLO_RS04585	ENOG4105BZU	Histidine kinase
ACLO_RS04590	ENOG4105CGK	Exodeoxyribonuclease III
ACLO_RS04620	ENOG4107QP8	phosphohexose isomerase
ACLO_RS04625	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
ACLO_RS04630	ENOG4107QKV	phosphomannomutase
ACLO_RS04665	ENOG4105NBK	UPF0345 protein
ACLO_RS04685	ENOG4105C3G	gtp-binding protein
ACLO_RS04690	ENOG4105C7N	Xanthine uracil vitamin C permease
ACLO_RS04695	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
ACLO_RS04710	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
ACLO_RS04715	ENOG4105C2W	permease
ACLO_RS04720	ENOG4108VPT	UPF0234 protein
ACLO_RS04740	ENOG4107VIJ	nudix hydrolase
ACLO_RS04750	ENOG4105HDD	phospholipase
ACLO_RS04755	ENOG4105DJV	ribulose-phosphate 3-epimerase
ACLO_RS04760	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
ACLO_RS04765	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ACLO_RS04770	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ACLO_RS04780	ENOG4105DQU	oxidoreductase, subunit beta
ACLO_RS04785	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
ACLO_RS04795	ENOG41060K3	Methyltransferase
ACLO_RS04800	ENOG4105QTX	Pfam:UPF0153
ACLO_RS04810	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ACLO_RS04820	ENOG4105VSH	4-oxalocrotonate tautomerase
ACLO_RS04830	ENOG4105DFA	alanine racemase domain protein
ACLO_RS04835	ENOG4105DZP	Membrane-associated zinc metalloprotease
ACLO_RS04840	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
ACLO_RS04845	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
ACLO_RS04850	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ACLO_RS04865	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
ACLO_RS04870	ENOG4105BZ1	(ABC) transporter
ACLO_RS04875	ENOG4105CJR	Integral membrane protein (MviN
ACLO_RS04885	ENOG4108RAC	Rubrerythrin
ACLO_RS04895	ENOG4105FEU	K -dependent Na -Ca exchanger
ACLO_RS04900	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ACLO_RS04905	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
ACLO_RS04945	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ACLO_RS04950	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACLO_RS04960	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
ACLO_RS04965	ENOG4106H78	methyltransferase
ACLO_RS04970	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ACLO_RS04980	ENOG4105E1F	short-chain dehydrogenase reductase
ACLO_RS04995	ENOG4105NQN	cytochrome C
ACLO_RS05020	ENOG4108PQF	modD protein
ACLO_RS05030	ENOG4105KTH	gatB Yqey
ACLO_RS05035	ENOG4105C5H	ABC transporter
ACLO_RS05045	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
ACLO_RS05050	ENOG4105DHT	Metal Dependent Phosphohydrolase
ACLO_RS05055	ENOG41076HS	cation diffusion facilitator family transporter
ACLO_RS05060	ENOG4105CHM	Aminotransferase
ACLO_RS05065	ENOG4108VKG	metal-dependent hydrolase
ACLO_RS05080	ENOG4108IYU	L-aspartate oxidase
ACLO_RS05085	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ACLO_RS05100	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
ACLO_RS05115	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ACLO_RS05155	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
ACLO_RS05160	ENOG4105PW4	Sugar fermentation stimulation protein homolog
ACLO_RS05175	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
ACLO_RS05180	ENOG4105EI2	Pseudouridine synthase
ACLO_RS05185	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ACLO_RS05190	ENOG4105DR4	Methyltransferase
ACLO_RS05215	ENOG4105E1F	short-chain dehydrogenase reductase
ACLO_RS05220	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ACLO_RS05275	ENOG4108JU5	Magnesium and cobalt efflux protein
ACLO_RS05280	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
ACLO_RS05285	ENOG4105DSF	transport protein
ACLO_RS05290	ENOG4105DHT	Metal Dependent Phosphohydrolase
ACLO_RS05305	ENOG4108JU6	CBS domain protein
ACLO_RS05320	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ACLO_RS05325	ENOG4108RZE	Tetr family transcriptional regulator
ACLO_RS05340	ENOG4105C1J	atp-dependent rna helicase
ACLO_RS05350	ENOG4105D7W	serine acetyltransferase
ACLO_RS05355	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
ACLO_RS05360	ENOG4105CUT	histidyl-tRNA synthetase
ACLO_RS05365	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
ACLO_RS05370	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
ACLO_RS05375	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
ACLO_RS05385	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
ACLO_RS05390	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
ACLO_RS05395	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
ACLO_RS05405	ENOG4105F8V	Hydrolase, tatD family
ACLO_RS05415	ENOG4105K6T	rare lipoprotein A
ACLO_RS05420	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
ACLO_RS05425	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
ACLO_RS05440	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
ACLO_RS05450	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ACLO_RS05455	ENOG41090Y0	FMN-binding protein
ACLO_RS05465	ENOG4105BZS	acriflavin resistance protein
ACLO_RS05475	ENOG410624X	efflux transporter, rnd family, mfp subunit
ACLO_RS05485	ENOG4105KHC	sulfurtransferase
ACLO_RS05495	ENOG4105CN7	Flagellar biosynthetic protein FliP
ACLO_RS05500	ENOG4107RVG	penicillin-binding protein
ACLO_RS05550	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
ACLO_RS05555	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ACLO_RS05570	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
ACLO_RS05580	ENOG4105DWV	Homoserine O-trans-acetylase
ACLO_RS05590	ENOG4105C98	muts2 protein
ACLO_RS05610	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
ACLO_RS05635	ENOG4105DKW	ABC transporter
ACLO_RS05650	ENOG4105CQC	Prephenate dehydratase
ACLO_RS05655	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ACLO_RS05675	ENOG4108V1U	phospholipid-binding protein
ACLO_RS05680	ENOG4105DUM	transcriptional regulator, lysR family
ACLO_RS05685	ENOG4105HMI	Membrane
ACLO_RS05695	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS05710	ENOG4105KVH	Transcriptional regulator
ACLO_RS05715	ENOG4105NF4	modulator of drug activity
ACLO_RS05725	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ACLO_RS05730	ENOG4108RCM	Nitroreductase
ACLO_RS05740	ENOG4105BZU	Histidine kinase
ACLO_RS05770	ENOG4105CBS	Chea signal transduction histidine kinase
ACLO_RS05785	ENOG4108QDE	fad dependent oxidoreductase
ACLO_RS05800	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_RS05810	ENOG4105QNF	Outer membrane lipoprotein
ACLO_RS05825	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
ACLO_RS05840	ENOG4105BZU	Histidine kinase
ACLO_RS05850	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
ACLO_RS05865	ENOG4105QNF	Outer membrane lipoprotein
ACLO_RS05870	ENOG4105CT4	transporter
ACLO_RS05875	ENOG4107FW0	short-chain dehydrogenase reductase
ACLO_RS05885	ENOG4105C5H	ABC transporter
ACLO_RS05890	ENOG4108S4H	thioesterase Superfamily protein
ACLO_RS05895	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_RS05900	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS05905	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_RS05910	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ACLO_RS06030	ENOG4105K8R	UPF0145 protein
ACLO_RS06085	ENOG4105CNU	cell division protein FtsK
ACLO_RS06090	ENOG4105CIN	aminoacyl-histidine dipeptidase
ACLO_RS06100	ENOG4105ETX	regulatoR
ACLO_RS06105	ENOG4105CRE	cytochrome C
ACLO_RS06140	ENOG4105VTR	Integrase
ACLO_RS06145	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
ACLO_RS06160	ENOG4105C5X	domain protein
ACLO_RS06180	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ACLO_RS06185	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ACLO_RS06190	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
ACLO_RS06210	ENOG4108Z0R	Transferase
ACLO_RS06215	ENOG4105CDH	Citrulline--aspartate ligase
ACLO_RS06225	ENOG4105D05	Receptor
ACLO_RS06235	ENOG4107QYG	anthranilate phosphoribosyltransferase
ACLO_RS06240	ENOG4105K8N	protein family UPF0079, ATPase
ACLO_RS06245	ENOG4108IUZ	ABC transporter
ACLO_RS06250	ENOG4105BZU	Histidine kinase
ACLO_RS06255	ENOG4105BZU	Histidine kinase
ACLO_RS06260	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
ACLO_RS06265	ENOG4105C2M	dna polymerase I
ACLO_RS06285	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
ACLO_RS06290	ENOG4105DF6	Fe-S oxidoreductase
ACLO_RS06300	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ACLO_RS06330	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
ACLO_RS06335	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ACLO_RS06345	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ACLO_RS06365	ENOG4105C4K	Nad synthetase
ACLO_RS06375	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
ACLO_RS06385	ENOG4105D4P	Coproporphyrinogen iii oxidase
ACLO_RS06390	ENOG4105DBV	ornithine carbamoyltransferase
ACLO_RS06395	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACLO_RS06410	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ACLO_RS06415	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_RS06420	ENOG4105D52	delta-aminolevulinic acid dehydratase
ACLO_RS06425	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
ACLO_RS06430	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ACLO_RS06460	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ACLO_RS06470	ENOG4107QX8	SPFH domain, Band 7 family protein
ACLO_RS06510	ENOG4105M8K	biopolymer transport protein
ACLO_RS06515	ENOG4105M15	transport protein ExbD
ACLO_RS06530	ENOG4105EYH	Exonuclease
ACLO_RS06570	ENOG4105JSC	dimethylmenaquinone methyltransferase
ACLO_RS06575	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
ACLO_RS06580	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ACLO_RS06585	ENOG4105I08	Pseudouridine synthase
ACLO_RS06620	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ACLO_RS06625	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
ACLO_RS06630	ENOG4108JJB	ABC transporter
ACLO_RS06635	ENOG4105EHG	Permease protein
ACLO_RS06660	ENOG4105CPC	Aldo Keto reductase
ACLO_RS06665	ENOG4105E2X	shikimate dehydrogenase
ACLO_RS06670	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
ACLO_RS06680	ENOG4105C6K	Malic enzyme
ACLO_RS06685	ENOG4105CIY	formyltetrahydrofolate deformylase
ACLO_RS06690	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
ACLO_RS06720	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
ACLO_RS06725	ENOG4105D9Q	decarboxylase (Beta subunit)
ACLO_RS06730	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ACLO_RS06750	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ACLO_RS06760	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACLO_RS06790	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ACLO_RS06800	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
ACLO_RS06805	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACLO_RS06815	ENOG4105EEI	dihydropteroate synthase
ACLO_RS06830	ENOG4105CFH	Aspartokinase
ACLO_RS06835	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
ACLO_RS06840	ENOG4105CSA	Coproporphyrinogen iii oxidase
ACLO_RS06845	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ACLO_RS06850	ENOG4105DGW	oligopeptidase A
ACLO_RS06870	ENOG4105F4R	Transcriptional regulator mode
ACLO_RS06875	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
ACLO_RS06885	ENOG4105E0C	molybdate abc transporter
ACLO_RS06895	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACLO_RS06900	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ACLO_RS06905	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
ACLO_RS06910	ENOG4105BZU	Histidine kinase
ACLO_RS06915	ENOG4105CBS	Chea signal transduction histidine kinase
ACLO_RS06920	ENOG4108VYJ	response regulator receiver protein
ACLO_RS06925	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ACLO_RS06935	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
ACLO_RS06955	ENOG4105CHH	sulfate transporter
ACLO_RS06960	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ACLO_RS06970	ENOG4105CNU	cell division protein FtsK
ACLO_RS06975	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACLO_RS06980	ENOG4108ZP8	Acetolactate synthase small subunit
ACLO_RS06985	ENOG4105C7K	acetolactate synthase
ACLO_RS06990	ENOG4105BZU	Histidine kinase
ACLO_RS07040	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
ACLO_RS07050	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ACLO_RS07065	ENOG4105CGY	Dna recombination protein
ACLO_RS07070	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
ACLO_RS07080	ENOG4107YD3	Thioesterase
ACLO_RS07090	ENOG4105BZU	Histidine kinase
ACLO_RS07095	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_RS07100	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_RS07105	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS07120	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_RS07125	ENOG4105BZU	Histidine kinase
ACLO_RS07130	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS07145	ENOG4105FGV	Chromate
ACLO_RS07150	ENOG4108UXE	Protein tyrosine phosphatase
ACLO_RS07165	ENOG41085FC	arsR family transcriptional regulator
ACLO_RS07170	ENOG4108UHV	Lipoprotein
ACLO_RS07175	ENOG4106032	Glutathionylspermidine synthase
ACLO_RS07180	ENOG4105BZU	Histidine kinase
ACLO_RS07185	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
ACLO_RS07205	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ACLO_RS07210	ENOG4105D60	lipoprotein releasing system transmembrane protein
ACLO_RS07225	ENOG4105E9K	Isocitrate dehydrogenase
ACLO_RS07230	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ACLO_RS07245	ENOG4105DJI	Methylaspartate mutase, E subunit
ACLO_RS07255	ENOG4105CEY	Amp-dependent synthetase and ligase
ACLO_RS07285	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
ACLO_RS07305	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ACLO_RS07315	ENOG410841J	DNA-binding protein Hu
ACLO_RS07330	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
ACLO_RS07340	ENOG4107YTP	response regulator receiver protein
ACLO_RS07355	ENOG4105DVC	DnaJ domain protein
ACLO_RS07360	ENOG4105KNI	merR family transcriptional Regulator
ACLO_RS07365	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACLO_RS07435	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
ACLO_RS07440	ENOG410829K	Lysine exporter protein (Lyse ygga)
ACLO_RS07445	ENOG4105D06	uba thif-type nad fad binding protein
ACLO_RS07450	ENOG4108M8H	domain protein
ACLO_RS07460	ENOG4105C8P	)-transporter
ACLO_RS07465	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
ACLO_RS07475	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACLO_RS07480	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ACLO_RS07490	ENOG4105D49	3-dehydroquinate synthase
ACLO_RS07495	ENOG4105C1J	atp-dependent rna helicase
ACLO_RS07500	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ACLO_RS07530	ENOG4105DY9	regulatoR
ACLO_RS07540	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
ACLO_RS07555	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
ACLO_RS07575	ENOG4105I03	Flagellin
ACLO_RS07575	ENOG4105I03	Flagellin
ACLO_RS07595	ENOG4108STX	response regulator
ACLO_RS07615	ENOG4105BZ1	(ABC) transporter
ACLO_RS07620	ENOG4105DSF	transport protein
ACLO_RS07630	ENOG4105BZU	Histidine kinase
ACLO_RS07635	ENOG4105K63	Thioredoxin
ACLO_RS07640	ENOG4105D3R	alkyl hydroperoxide reductase
ACLO_RS07645	ENOG4105BZU	Histidine kinase
ACLO_RS07655	ENOG4105D17	glycoside hydrolase, family 3 domain protein
ACLO_RS07680	ENOG4105DAA	L-lactate
ACLO_RS07685	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ACLO_RS07715	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ACLO_RS07720	ENOG4105BZU	Histidine kinase
ACLO_RS07730	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
ACLO_RS07735	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ACLO_RS07740	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ACLO_RS07745	ENOG4108ZT0	50S ribosomal protein l17
ACLO_RS07750	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACLO_RS07755	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ACLO_RS07760	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
ACLO_RS07765	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACLO_RS07770	ENOG41067V7	50S ribosomal protein L36
ACLO_RS07785	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
ACLO_RS07790	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ACLO_RS07795	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ACLO_RS07815	ENOG4105NBK	UPF0345 protein
ACLO_RS07820	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ACLO_RS07845	ENOG4105CNI	cell division protein FtsW
ACLO_RS07850	ENOG4105C34	Pseudouridine synthase
ACLO_RS07855	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
ACLO_RS07860	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ACLO_RS07865	ENOG4105CAK	Cell division ATP-binding protein ftsE
ACLO_RS07880	ENOG4108UPT	UPF0178 protein
ACLO_RS07890	ENOG4105C5H	ABC transporter
ACLO_RS07905	ENOG4105C0D	helicase
ACLO_RS07920	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
ACLO_RS07925	ENOG4105C25	Primosomal protein n'
ACLO_RS07955	ENOG4105C45	hydrogenase expression formation protein (HypE)
ACLO_RS07975	ENOG4105CQS	hydrogenase expression formation protein HypD
ACLO_RS07980	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
ACLO_RS07985	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
ACLO_RS08005	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
ACLO_RS08015	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS08025	ENOG4105CBX	hi0933 family
ACLO_RS08040	ENOG4105VCH	membrane
ACLO_RS08050	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
ACLO_RS08090	ENOG41080XP	Cbs domain
ACLO_RS08130	ENOG4105DPX	Hydrogenase, large subunit
ACLO_RS08135	ENOG4105E3S	small subunit
ACLO_RS08150	ENOG4108IG5	Transcriptional regulator
ACLO_RS08155	ENOG4107QIJ	Aconitate hydratase 2
ACLO_RS08180	ENOG4108IQE	Amp-dependent synthetase and ligase
ACLO_RS08185	ENOG4105CHU	acetyl-coa acetyltransferase
ACLO_RS08195	ENOG4107QPN	acyl-Coa dehydrogenase
ACLO_RS08250	ENOG4105BZU	Histidine kinase
ACLO_RS08270	ENOG4105CDY	transcriptional regulatory protein
ACLO_RS08275	ENOG4105DR5	peptidase
ACLO_RS08280	ENOG410903C	(LipO)protein
ACLO_RS08295	ENOG4108URH	decarboxylase
ACLO_RS08300	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
ACLO_RS08345	ENOG4105C94	Transporter
ACLO_RS08350	ENOG4108ISG	Major Facilitator
ACLO_RS08370	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ACLO_RS08375	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ACLO_RS08385	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
ACLO_RS08405	ENOG4105C1J	atp-dependent rna helicase
ACLO_RS08410	ENOG4105DDY	UPF0142 protein ycaO
ACLO_RS08430	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS08440	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ACLO_RS08445	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
ACLO_RS08460	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
ACLO_RS08470	ENOG4107S7U	Sulfide dehydrogenase
ACLO_RS08490	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
ACLO_RS08495	ENOG4105C8W	ABC transporter
ACLO_RS08500	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ACLO_RS08510	ENOG4105F4R	Transcriptional regulator mode
ACLO_RS08520	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
ACLO_RS08530	ENOG4105QAX	Iron-sulfur
ACLO_RS08565	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ACLO_RS08570	ENOG4105K3M	)-transporter
ACLO_RS08605	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ACLO_RS08645	ENOG4108KS2	transglutaminase domain protein
ACLO_RS08650	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
ACLO_RS08660	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
ACLO_RS08665	ENOG4105EM7	Selenocysteine-specific translation elongation factor
ACLO_RS08690	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ACLO_RS08695	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_RS08700	ENOG4105BZU	Histidine kinase
ACLO_RS08705	ENOG4105BZU	Histidine kinase
ACLO_RS08710	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_RS08715	ENOG4105BZU	Histidine kinase
ACLO_RS08750	ENOG4105BZU	Histidine kinase
ACLO_RS08770	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ACLO_RS08775	ENOG4105EKE	dihydroorotase
ACLO_RS08780	ENOG4108N6H	6-pyruvoyl tetrahydrobiopterin synthase
ACLO_RS08790	ENOG4105DCI	Phosphohydrolase
ACLO_RS08795	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
ACLO_RS08805	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
ACLO_RS08810	ENOG4105BZU	Histidine kinase
ACLO_RS08815	ENOG4105C1J	atp-dependent rna helicase
ACLO_RS08830	ENOG4105BZU	Histidine kinase
ACLO_RS08850	ENOG4105E7W	lamb ycsf family protein
ACLO_RS08870	ENOG4105CMI	transporter
ACLO_RS08875	ENOG4105CJ1	ABC, transporter
ACLO_RS08880	ENOG4105D0S	secretion protein (HlyD
ACLO_RS08890	ENOG4105CJ3	phosphate transporter
ACLO_RS08905	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
ACLO_RS08910	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
ACLO_RS08915	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
ACLO_RS08925	ENOG4105BZU	Histidine kinase
ACLO_RS08930	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_RS08945	ENOG4105F1S	paraquat-inducible protein a
ACLO_RS08960	ENOG4105BZU	Histidine kinase
ACLO_RS08970	ENOG4105C08	Histidine kinase
ACLO_RS08975	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
ACLO_RS08980	ENOG4105CZN	Potassium uptake protein
ACLO_RS09000	ENOG4105C7I	Dehydrogenase
ACLO_RS09005	ENOG4108Z66	YbaK ebsC protein
ACLO_RS09010	ENOG4105F1N	DNA alkylation repair
ACLO_RS09025	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ACLO_RS09035	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ACLO_RS09040	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
ACLO_RS09050	ENOG4108IJ0	Aspartate ammonia-lyase
ACLO_RS09055	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ACLO_RS09060	ENOG4105CQZ	Histidine kinase
ACLO_RS09070	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
ACLO_RS09075	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
ACLO_RS09080	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ACLO_RS09095	ENOG4108UQY	Iron-storage protein
ACLO_RS09100	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
ACLO_RS09110	ENOG4105M8F	Biopolymer transport protein exbD tolR
ACLO_RS09115	ENOG4105E02	MotA TolQ exbB proton channel
ACLO_RS09120	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ACLO_RS09125	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
ACLO_RS09130	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
ACLO_RS09135	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
ACLO_RS09140	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ACLO_RS09145	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
ACLO_RS09155	ENOG4105FA0	parb-like partition protein
ACLO_RS09160	ENOG4107QJE	Chromosome Partitioning Protein
ACLO_RS09165	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
ACLO_RS09175	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ACLO_RS09180	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ACLO_RS09185	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACLO_RS09190	ENOG4105K46	50S ribosomal protein l27
ACLO_RS09195	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
ACLO_RS09205	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ACLO_RS09215	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
ACLO_RS09220	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ACLO_RS09230	ENOG4105D0M	Protease HtpX homolog
ACLO_RS09245	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
ACLO_RS09255	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ACLO_RS09260	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
ACLO_RS09265	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
ACLO_RS09270	ENOG4105VG0	50S ribosomal protein l34
ACLO_RS09275	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ACLO_RS09290	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ACLO_RS09305	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ACLO_RS09310	ENOG4105E0X	reductase
ACLO_RS09315	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
ACLO_RS09340	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_RS09350	ENOG4105C72	UPF0176 protein
ACLO_RS09355	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ACLO_RS09365	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACLO_RS09370	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACLO_RS09375	ENOG4107TS3	membrane protein, TerC
ACLO_RS09385	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS09390	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS09395	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS09400	ENOG4108V06	Glutathione peroxidase
ACLO_RS09405	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
ACLO_RS09410	ENOG4108KN0	Choline kinase
ACLO_RS09415	ENOG4105BZU	Histidine kinase
ACLO_RS09420	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ACLO_RS09425	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ACLO_RS09450	ENOG4105DC1	bifunctional purine biosynthesis protein purh
ACLO_RS09455	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
ACLO_RS09465	ENOG4105DR5	peptidase
ACLO_RS09480	ENOG4108JPW	Aminotransferase
ACLO_RS09485	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
ACLO_RS09495	ENOG4105CFH	Aspartokinase
ACLO_RS09500	ENOG4105EUJ	GTP cyclohydrolase i
ACLO_RS09505	ENOG4105D7N	magnesium and cobalt transport protein CorA
ACLO_RS09510	ENOG4105D7Q	type ii secretion system
ACLO_RS09515	ENOG4107QHF	type ii secretion system protein e
ACLO_RS09530	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
ACLO_RS09535	ENOG4105C0P	Mg chelatase subunit ChlI
ACLO_RS09545	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ACLO_RS09550	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ACLO_RS09555	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
ACLO_RS09565	ENOG4105CSR	polyphosphate kinase 2
ACLO_RS09570	ENOG4105CSR	polyphosphate kinase 2
ACLO_RS09580	ENOG4105VCQ	rubredoxin
ACLO_RS09595	ENOG4105DFP	Integrase
ACLO_RS09600	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ACLO_RS09785	ENOG4108VWS	Yaeq family
ACLO_RS09805	ENOG4105C28	cystathionine
ACLO_RS09825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ACLO_RS09830	ENOG4105WQG	acetyltransferase
ACLO_RS09840	ENOG4105D7X	high-affinity nickel-transporter
ACLO_RS09855	ENOG4105D65	subunit l
ACLO_RS09860	ENOG4108ZE9	Monovalent cation H antiporter subunit C
ACLO_RS09865	ENOG4107R4Z	monovalent cation h antiporter subunit d
ACLO_RS09870	ENOG4105SC1	monovalent cation H antiporter subunit E
ACLO_RS09875	ENOG4105W4C	monovalent cation H antiporter subunit F
ACLO_RS09880	ENOG4105KJM	monovalent cation h antiporter subunit g
ACLO_RS09885	ENOG4105CHR	reductase
ACLO_RS09895	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ACLO_RS09900	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS09905	ENOG4107XTP	(EAL) domain protein
ACLO_RS09910	ENOG4105D7T	ABC transporter
ACLO_RS09930	ENOG4108IFG	nitrite reductase, (NAD(P)H)
ACLO_RS09980	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ACLO_RS09985	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS10130	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACLO_RS10140	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACLO_RS10145	ENOG4105D64	Mechanosensitive ion channel
ACLO_RS10170	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
ACLO_RS10185	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ACLO_RS10190	ENOG4105BZU	Histidine kinase
ACLO_RS10195	ENOG4107VQW	regulatoR
ACLO_RS10205	ENOG4107QKV	phosphomannomutase
ACLO_RS10235	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ACLO_RS10250	ENOG4105CE1	Ferrous iron transport protein b
ACLO_RS10265	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
ACLO_RS10270	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
ACLO_RS10275	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
ACLO_RS10280	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ACLO_RS10285	ENOG4105F4G	Membrane
ACLO_RS10295	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
ACLO_RS10350	ENOG41082XB	radical SAM domain protein
ACLO_RS10355	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
ACLO_RS10365	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ACLO_RS10380	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
ACLO_RS10390	ENOG4105VB9	50S ribosomal protein l28
ACLO_RS10400	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
ACLO_RS10405	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
ACLO_RS10410	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
ACLO_RS10415	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
ACLO_RS10420	ENOG4105DKP	glycosyl transferase, family 9
ACLO_RS10435	ENOG4107R51	Glycosyl transferase, family 2
ACLO_RS10450	ENOG4105CPK	Glycosyl transferase (Group 1
ACLO_RS10455	ENOG4107S6X	Glycosyl transferase, family 2
ACLO_RS10470	ENOG4108RJ9	Glycosyl transferase, family 2
ACLO_RS10475	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ACLO_RS10490	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ACLO_RS10495	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ACLO_RS10515	ENOG4105DKP	glycosyl transferase, family 9
ACLO_RS10525	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
ACLO_RS10535	ENOG4105BZ8	glutamate synthase
ACLO_RS10540	ENOG4105CBC	glutamate synthase
ACLO_RS10610	ENOG4105C5E	polysaccharide biosynthesis protein
ACLO_RS10615	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ACLO_RS10620	ENOG4105ESV	Glycosyl transferase, family 4
ACLO_RS10685	ENOG4105K64	Glycosyl transferase, family 2
ACLO_RS10695	ENOG4108RT7	Glycosyl transferase, family 2
ACLO_RS10700	ENOG410650X	lipopolysaccharide core region biosynthetic process
ACLO_RS10705	ENOG4108UW5	maltose o-acetyltransferase
ACLO_RS10720	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ACLO_RS10725	ENOG4105F0R	Cytidylyltransferase
ACLO_RS10740	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ACLO_RS10760	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ACLO_RS10765	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ACLO_RS10770	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
ACLO_RS10775	ENOG4105M7K	Involved in the transcription termination process (By similarity)
ACLO_RS10780	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
ACLO_RS10815	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
ACLO_RS10835	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ACLO_RS10850	ENOG4105GVR	general secretion pathway protein D
ACLO_RS10855	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
ACLO_RS10860	ENOG4105DX0	Hemolysin A
ACLO_RS10865	ENOG4105DTN	riboflavin biosynthesis protein ribF
ACLO_RS10870	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
ACLO_RS10875	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACLO_RS10885	ENOG4105CQB	FAD linked oxidase domain protein
ACLO_RS10890	ENOG4107S2Z	UPF0761 membrane protein
ACLO_RS10930	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ACLO_RS10935	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
ACLO_RS10940	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ACLO_RS10955	ENOG4105DJG	MaoC domain protein dehydratase
ACLO_RS10975	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS10980	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
ACLO_RS10985	ENOG4107XC4	flavin reductase domain protein, FMN-binding
ACLO_RS11015	ENOG4105D7B	Flagellar biosynthesis protein flha
ACLO_RS11020	ENOG4105DTJ	flagellar hook-associated protein
ACLO_RS11025	ENOG4108JIR	Flagellum-specific ATP synthase
ACLO_RS11035	ENOG4105D00	flagellar biosynthetic protein flhB
ACLO_RS11050	ENOG4108ZC9	flagellar basal-body rod protein flgc
ACLO_RS11055	ENOG41084DA	flagellar hook-basal body complex protein fliE
ACLO_RS11065	ENOG4107R21	site-determining protein
ACLO_RS11070	ENOG4105FZW	flagellar biosynthesis regulator FlhF
ACLO_RS11095	ENOG4105E14	MotA TolQ exbB proton channel
ACLO_RS11100	ENOG4105DD5	Flagellar motor switch protein
ACLO_RS11120	ENOG4105BZE	flagellar hook protein, FlgE
ACLO_RS11125	ENOG4108JQA	flagellar
ACLO_RS11135	ENOG4105DD5	Flagellar motor switch protein
ACLO_RS11145	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
ACLO_RS11150	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
ACLO_RS11155	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
ACLO_RS11160	ENOG4105CGA	flagellar basal-body rod protein FlgG
ACLO_RS11175	ENOG4105CGA	flagellar basal-body rod protein FlgG
ACLO_RS11190	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
ACLO_RS11200	ENOG4105K5M	30s ribosomal protein S16
ACLO_RS11205	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACLO_RS11215	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
ACLO_RS11225	ENOG4105EGD	dinuclear metal center protein, YbgI family
ACLO_RS11230	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
ACLO_RS11240	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
ACLO_RS11250	ENOG4105CFP	Peptidase U32
ACLO_RS11255	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ACLO_RS11255	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ACLO_RS11260	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ACLO_RS11265	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
ACLO_RS11270	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ACLO_RS11275	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ACLO_RS11280	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ACLO_RS11345	ENOG4105BZU	Histidine kinase
ACLO_RS11375	ENOG4107S1Q	Phosphatase
ACLO_RS11430	ENOG4105DFP	Integrase
ACLO_RS11445	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACLO_RS11450	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACLO_RS11455	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
ACLO_RS11460	ENOG4108VZM	50s ribosomal protein L10
ACLO_RS11465	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
ACLO_RS11470	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
ACLO_RS11475	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
ACLO_RS11490	ENOG41086AR	50S ribosomal protein L33
ACLO_RS11495	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ACLO_RS11520	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
ACLO_RS11525	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ACLO_RS11530	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ACLO_RS11540	ENOG4108JQC	penicillin-binding protein 1A
ACLO_RS11545	ENOG4105C5F	glutamine synthetase
ACLO_RS11555	ENOG4105BZU	Histidine kinase
ACLO_RS11560	ENOG4108ZEX	molybdopterin converting factor, subunit 2
ACLO_RS11570	ENOG4108XUR	Pfam:DUF178
ACLO_RS11575	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ACLO_RS11585	ENOG4105CNI	cell division protein FtsW
ACLO_RS11590	ENOG4105CJN	penicillin-binding protein
ACLO_RS11595	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ACLO_RS11635	ENOG4105DDQ	anthranilate synthase
ACLO_RS11645	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
ACLO_RS11650	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACLO_RS11660	ENOG4105BZU	Histidine kinase
ACLO_RS11695	ENOG4105BZU	Histidine kinase
ACLO_RS11715	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ACLO_RS11720	ENOG4107T5V	SNARE associated Golgi
ACLO_RS11730	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
ACLO_RS11735	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
ACLO_RS11745	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
ACLO_RS11750	ENOG4105C7B	Threonine dehydratase
ACLO_RS11755	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
ACLO_RS11765	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
ACLO_RS11770	ENOG4105CAS	nag kinase
ACLO_RS11775	ENOG4107QID	Threonine synthase
ACLO_RS11785	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ACLO_RS11800	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
ACLO_RS11810	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ACLO_RS11815	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
ACLO_RS11825	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
ACLO_RS11830	ENOG4105CHR	reductase
ACLO_RS11835	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ACLO_RS11840	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ACLO_RS11845	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
ACLO_RS11850	ENOG4105K59	histidine triad (HIT) protein
ACLO_RS11855	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ACLO_RS11860	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ACLO_RS11865	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ACLO_RS11870	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
ACLO_RS11875	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ACLO_RS11880	ENOG4108JQ1	Dehydrogenase
ACLO_RS11885	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
ACLO_RS11890	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ACLO_RS11895	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
ACLO_RS11900	ENOG4105MGB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
ACLO_RS11905	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ACLO_RS11915	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
ACLO_RS11925	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACLO_RS11940	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ACLO_RS11950	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
ACLO_RS11960	ENOG4105YIC	Major outer membrane protein
ACLO_RS11990	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
ACLO_RS12030	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
ACLO_RS12035	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
ACLO_RS12040	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
ACLO_RS12045	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ACLO_RS12050	ENOG4105C4R	Atp-dependent dna helicase
ACLO_RS12055	ENOG4105DUM	transcriptional regulator, lysR family
ACLO_RS12060	ENOG4105N5T	Radical SAM Protein
ACLO_RS12065	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
ACLO_RS12070	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
ACLO_RS12075	ENOG4105C3M	thioredoxin reductase
ACLO_RS12080	ENOG4105K63	Thioredoxin
ACLO_RS12085	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ACLO_RS12110	ENOG4107TT5	NLP P60 protein
ACLO_RS12115	ENOG4107TT5	NLP P60 protein
ACLO_RS12130	ENOG4107YJQ	MAF-like protein
ACLO_RS12135	ENOG4105CA0	peroxidase
ACLO_RS12140	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ACLO_RS12145	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ACLO_RS12150	ENOG4105CQC	Prephenate dehydratase
ACLO_RS12155	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ACLO_RS12160	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
ACLO_RS12165	ENOG4105CP7	Triose-phosphate isomerase
ACLO_RS12170	ENOG4105BZA	Phosphoglycerate kinase
ACLO_RS12180	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
ACLO_RS12190	ENOG4105C75	arginyL-tRNA synthetase
ACLO_RS12195	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ACLO_RS12200	ENOG4105WMR	Protein CrcB homolog
ACLO_RS12205	ENOG4105E9Q	Acyl-transferase
ACLO_RS12215	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
ACLO_RS12220	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
ACLO_RS12225	ENOG4105C8V	SAICAR synthetase
ACLO_RS12230	ENOG4105CN1	protease
ACLO_RS12245	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ACLO_RS12260	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACLO_RS12290	ENOG4105C01	Dihydroxy-acid dehydratase
ACLO_RS12295	ENOG4105C0H	protease
ACLO_RS12315	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
ACLO_RS12320	ENOG4105CGD	Nad-dependent epimerase dehydratase
ACLO_RS12335	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
ACLO_RS12345	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
ACLO_RS12355	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ACLO_RS12360	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
ACLO_RS12370	ENOG41081FY	multiple antibiotic resistance (MarC)-related
ACLO_RS12375	ENOG4105F0R	Cytidylyltransferase
ACLO_RS12380	ENOG4108K7V	UPF0284 protein
ACLO_RS12395	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
ACLO_RS12400	ENOG4105K63	Thioredoxin
ACLO_RS12405	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
ACLO_RS12420	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
ACLO_RS12435	ENOG4105BZU	Histidine kinase
ACLO_RS12440	ENOG4105DJ4	phosphatidylserine decarboxylase
ACLO_RS12450	ENOG4105CA3	membrane-bound lytic murein transglycosylase
ACLO_RS12460	ENOG4105CFG	Acts as a chaperone (By similarity)
ACLO_RS12465	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACLO_RS12475	ENOG4105H1G	trap transporter solute receptor taxi family
ACLO_RS12485	ENOG4105WH1	Two component transcriptional regulator luxr family
ACLO_RS12495	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ACLO_RS12510	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ACLO_RS12515	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
ACLO_RS12520	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ACLO_RS12530	ENOG4105CQR	helicase
ACLO_RS12535	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ACLO_RS12545	ENOG4105I03	Flagellin
ACLO_RS12565	ENOG4105F0R	Cytidylyltransferase
ACLO_RS12580	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
ACLO_RS12600	ENOG4105EWK	phytoene
ACLO_RS12605	ENOG4105D2T	synthase
ACLO_RS12615	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ACLO_RS12625	ENOG4105CB5	ATP-dependent DNA helicase recG
ACLO_RS12635	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ACLO_RS12640	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ACLO_RS12655	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
ACLO_RS12675	ENOG4105E63	Pfam:DUF178
ACLO_RS12685	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_RS12690	ENOG4105C8S	subunit m
ACLO_RS12695	ENOG4105D65	subunit l
ACLO_RS12700	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_RS12710	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_RS12715	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ACLO_RS12735	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_RS12740	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACLO_RS12745	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_RS12750	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACLO_RS12755	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
ACLO_RS12780	ENOG4105CHH	sulfate transporter
ACLO_RS12785	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
ACLO_RS12795	ENOG4105C8J	)-transporter
ACLO_RS12805	ENOG4105WPN	DNA integration recombination invertion protein
ACLO_RS12815	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ACLO_RS12820	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACLO_RS12825	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
ACLO_RS12845	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
ACLO_RS12860	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ACLO_RS12865	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ACLO_RS12870	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
ACLO_RS12900	ENOG4105C0B	DNA polymerase III (alpha subunit)
ACLO_RS12905	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ACLO_RS12920	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ACLO_RS12955	ENOG4105HFZ	Membrane
ACLO_RS12960	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ACLO_RS12970	ENOG4105NU9	Preprotein translocase subunit SecG
ACLO_RS12980	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ACLO_RS12985	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ACLO_RS12995	ENOG4105D8G	Major Facilitator superfamily
ACLO_RS13000	ENOG4105EGS	Mechanosensitive ion channel
ACLO_RS13010	ENOG410802Z	Protein of unknown function (DUF328)
ACLO_RS13015	ENOG4105K5B	UPF0225 protein
ACLO_RS13040	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
ACLO_RS13050	ENOG4105C7K	acetolactate synthase
ACLO_RS13055	ENOG4108V0P	LemA family
ACLO_RS13070	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ACLO_RS13080	ENOG4108RMU	ferritin dps family protein
ACLO_RS13090	ENOG4105C2C	drug resistance transporter, Bcr CflA
ACLO_RS13095	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS13140	ENOG4105CBX	hi0933 family
ACLO_RS13165	ENOG4105C6T	cysteine synthase
ACLO_RS13180	ENOG4105C11	sulfate adenylyltransferase), subunit 2
ACLO_RS13185	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
ACLO_RS13190	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
ACLO_RS13195	ENOG4105C9B	Cysteine desulfurase
ACLO_RS13210	ENOG4107RN3	metallophosphoesterase
ACLO_RS13215	ENOG4107Y70	Heat shock protein
ACLO_RS13235	ENOG4108IJ6	ABC transporter
ACLO_RS13245	ENOG4108I5D	sulfate abc transporter
ACLO_RS13250	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
ACLO_RS13280	ENOG4105CI3	gtp-binding protein typa
ACLO_RS13295	ENOG41080IJ	Diacylglycerol kinase
ACLO_RS13325	ENOG41066VF	YeeE YedE family protein
ACLO_RS13335	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
ACLO_RS13340	ENOG4105CSV	Glutaminase
ACLO_RS13345	ENOG4105EN6	Membrane
ACLO_RS13355	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ACLO_RS13360	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
ACLO_RS13370	ENOG4105CDU	Replicative dna helicase
ACLO_RS13380	ENOG4105FA0	parb-like partition protein
ACLO_RS13385	ENOG4107QJE	Chromosome Partitioning Protein
ACLO_RS13395	ENOG4105D05	Receptor
ACLO_RS13430	ENOG4105D05	Receptor
ACLO_RS13445	ENOG4105ETX	regulatoR
ACLO_RS13455	ENOG4105CAF	HipA N-terminal domain protein
ACLO_RS13505	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_RS13510	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS13515	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS13535	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_RS13540	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS13550	ENOG4105CBS	Chea signal transduction histidine kinase
ACLO_RS13570	ENOG4105D5G	Transposase
ACLO_RS13600	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
ACLO_RS13615	ENOG4105E4P	ATPase (AAA
ACLO_RS13695	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
ACLO_RS13730	ENOG4105CAF	HipA N-terminal domain protein
ACLO_RS13740	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
ACLO_RS13745	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
ACLO_RS13785	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS13795	ENOG41062JF	Transcriptional regulator
ACLO_RS13815	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACLO_RS13835	ENOG4108UAJ	Transcriptional regulator
ACLO_RS13845	ENOG4108JJA	ABC, transporter
ACLO_RS13850	ENOG4105CDV	Ompa motb domain protein
ACLO_RS13855	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ACLO_RS13885	ENOG4105BZU	Histidine kinase
ACLO_RS13925	ENOG41075H3	AraC family transcriptional regulator
ACLO_RS13945	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ACLO_RS13970	ENOG4105EQD	regulatoR
ACLO_RS13975	ENOG4105BZU	Histidine kinase
ACLO_RS13990	ENOG4105C9Q	fumarate hydratase class II
ACLO_RS14030	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_RS14035	ENOG4105BZU	Histidine kinase
ACLO_RS14040	ENOG4105CQC	Prephenate dehydratase
ACLO_RS14055	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
ACLO_RS14060	ENOG4108JNI	Alpha beta hydrolase
ACLO_RS14065	ENOG4105DEN	Luciferase family
ACLO_RS14080	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
ACLO_RS14085	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
ACLO_RS14110	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
ACLO_RS14130	ENOG4105HF0	Membrane
ACLO_RS14170	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ACLO_RS14175	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
ACLO_RS14180	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)