locus-tag	class	description
ACRYA_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACRYA_RS00010	COG0592	DNA-directed DNA polymerase activity
ACRYA_RS00015	COG0187	DNA topoisomerase II activity
ACRYA_RS00020	COG0492	ferredoxin-NADP+ reductase activity
ACRYA_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACRYA_RS00045	COG0500	methyltransferase
ACRYA_RS00105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACRYA_RS00115	COG0840	transmembrane signaling receptor activity
ACRYA_RS00120	COG2081	HI0933 family
ACRYA_RS00135	COG1959	2 iron, 2 sulfur cluster binding
ACRYA_RS00150	COG0175	sulfate reduction
ACRYA_RS00155	COG0175	sulfate reduction
ACRYA_RS00160	COG2895	sulfate adenylyltransferase (ATP) activity
ACRYA_RS00170	COG2814	Major facilitator Superfamily
ACRYA_RS00175	COG0783	Belongs to the Dps family
ACRYA_RS00180	COG0546	phosphoglycolate phosphatase activity
ACRYA_RS00190	COG1012	belongs to the aldehyde dehydrogenase family
ACRYA_RS00195	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACRYA_RS00210	COG3022	response to hydroperoxide
ACRYA_RS00215	COG0270	DNA (cytosine-5-)-methyltransferase activity
ACRYA_RS00235	COG0270	DNA (cytosine-5-)-methyltransferase activity
ACRYA_RS00245	COG3022	response to hydroperoxide
ACRYA_RS00265	COG3022	response to hydroperoxide
ACRYA_RS00285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACRYA_RS00290	COG0233	cytoplasmic translational termination
ACRYA_RS00295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACRYA_RS00305	COG0352	thiamine-phosphate diphosphorylase activity
ACRYA_RS00310	COG0670	Belongs to the BI1 family
ACRYA_RS00340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACRYA_RS00420	COG1459	type II secretion system
ACRYA_RS00425	COG0598	Magnesium transport protein CorA
ACRYA_RS00440	COG1178	ABC-type Fe3 transport system permease component
ACRYA_RS00445	COG1840	ABC-type Fe3 transport system, periplasmic component
ACRYA_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
ACRYA_RS00500	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACRYA_RS00505	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACRYA_RS00510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACRYA_RS00515	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACRYA_RS00520	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACRYA_RS00525	COG1077	Cell shape determining protein MreB Mrl
ACRYA_RS00540	COG0445	tRNA wobble uridine modification
ACRYA_RS00550	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACRYA_RS00555	COG1028	Short-chain dehydrogenase reductase Sdr
ACRYA_RS00560	COG0659	secondary active sulfate transmembrane transporter activity
ACRYA_RS00575	COG1222	aaa ATPase
ACRYA_RS00585	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACRYA_RS00590	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACRYA_RS00610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACRYA_RS00615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACRYA_RS00625	COG1086	Polysaccharide biosynthesis protein
ACRYA_RS00630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACRYA_RS00635	COG1083	cytidylyl-transferase
ACRYA_RS00640	COG3980	spore coat polysaccharide biosynthesis protein
ACRYA_RS00645	COG2089	acid synthase
ACRYA_RS00660	COG1028	Short-chain dehydrogenase reductase Sdr
ACRYA_RS00665	COG0318	PFAM AMP-dependent synthetase and ligase
ACRYA_RS00665	COG0204	Acyl-transferase
ACRYA_RS00685	COG0438	transferase activity, transferring glycosyl groups
ACRYA_RS00685	COG1216	Glycosyl transferase, family 2
ACRYA_RS00695	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACRYA_RS00710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACRYA_RS00750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACRYA_RS00760	COG2089	acid synthase
ACRYA_RS00765	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACRYA_RS00785	COG1083	cytidylyl-transferase
ACRYA_RS00790	COG1028	Short-chain dehydrogenase reductase Sdr
ACRYA_RS00810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACRYA_RS00815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACRYA_RS00825	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACRYA_RS00830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACRYA_RS00835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACRYA_RS00850	COG0101	tRNA pseudouridine synthase activity
ACRYA_RS00860	COG1420	regulation of RNA biosynthetic process
ACRYA_RS00865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACRYA_RS00870	COG0443	Heat shock 70 kDa protein
ACRYA_RS00890	COG2121	Domain of unknown function (DUF374)
ACRYA_RS00895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACRYA_RS00905	COG0195	Participates in both transcription termination and antitermination
ACRYA_RS00910	COG0215	cysteine-tRNA ligase activity
ACRYA_RS00915	COG1393	Belongs to the ArsC family
ACRYA_RS00920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACRYA_RS00925	COG0343	queuine tRNA-ribosyltransferase activity
ACRYA_RS00990	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACRYA_RS00995	COG0210	DNA helicase
ACRYA_RS01020	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACRYA_RS01025	COG0557	exoribonuclease II activity
ACRYA_RS01035	COG1466	dna polymerase III delta subunit
ACRYA_RS01040	COG0360	Binds together with S18 to 16S ribosomal RNA
ACRYA_RS01045	COG0629	single-stranded DNA binding
ACRYA_RS01050	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACRYA_RS01055	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACRYA_RS01070	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACRYA_RS01080	COG0157	Belongs to the NadC ModD family
ACRYA_RS01095	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACRYA_RS01105	COG0083	homoserine kinase activity
ACRYA_RS01115	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACRYA_RS01120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACRYA_RS01125	COG0779	Required for maturation of 30S ribosomal subunits
ACRYA_RS01130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACRYA_RS01130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACRYA_RS01135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACRYA_RS01140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACRYA_RS01145	COG1185	polyribonucleotide nucleotidyltransferase activity
ACRYA_RS01145	COG0539	negative regulation of cytoplasmic translation
ACRYA_RS01150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACRYA_RS01155	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACRYA_RS01160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACRYA_RS01160	COG0072	phenylalanine-tRNA ligase activity
ACRYA_RS01165	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACRYA_RS01170	COG0537	adenosine 5'-monophosphoramidase activity
ACRYA_RS01175	COG0825	malonyl-CoA metabolic process
ACRYA_RS01180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACRYA_RS01185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACRYA_RS01195	COG0602	queuosine metabolic process
ACRYA_RS01205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACRYA_RS01225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACRYA_RS01230	COG0723	plastoquinol--plastocyanin reductase activity
ACRYA_RS01235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACRYA_RS01240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACRYA_RS01255	COG0356	it plays a direct role in the translocation of protons across the membrane
ACRYA_RS01260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACRYA_RS01265	COG0191	fructose-bisphosphate aldolase activity
ACRYA_RS01275	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS01280	COG0642	Histidine kinase
ACRYA_RS01290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACRYA_RS01300	COG2199	diguanylate cyclase activity
ACRYA_RS01300	COG2200	EAL domain
ACRYA_RS01300	COG3287	FIST C domain
ACRYA_RS01320	COG3043	anaerobic respiration
ACRYA_RS01325	COG0348	domain, Protein
ACRYA_RS01330	COG0437	4 iron, 4 sulfur cluster binding
ACRYA_RS01335	COG0243	molybdopterin cofactor binding
ACRYA_RS01350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACRYA_RS01355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACRYA_RS01360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACRYA_RS01370	COG2404	hydrolase activity, acting on ester bonds
ACRYA_RS01380	COG0840	transmembrane signaling receptor activity
ACRYA_RS01385	COG0840	transmembrane signaling receptor activity
ACRYA_RS01410	COG2030	dehydratase
ACRYA_RS01425	COG1401	restriction endodeoxyribonuclease activity
ACRYA_RS01435	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACRYA_RS01440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACRYA_RS01445	COG0542	response to heat
ACRYA_RS01485	COG0148	phosphopyruvate hydratase activity
ACRYA_RS01500	COG2814	Major facilitator Superfamily
ACRYA_RS01510	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACRYA_RS01515	COG0049	tRNA binding
ACRYA_RS01520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACRYA_RS01525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACRYA_RS01530	COG0497	DNA recombination
ACRYA_RS01535	COG0840	transmembrane signaling receptor activity
ACRYA_RS01540	COG0826	peptidase U32
ACRYA_RS01550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACRYA_RS01560	COG0752	glycyl-tRNA synthetase alpha subunit
ACRYA_RS01565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACRYA_RS01575	COG1519	Transferase
ACRYA_RS01575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACRYA_RS01580	COG0564	pseudouridine synthase activity
ACRYA_RS01585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACRYA_RS01590	COG0228	four-way junction DNA binding
ACRYA_RS01595	COG1837	Belongs to the UPF0109 family
ACRYA_RS01600	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACRYA_RS01620	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS01630	COG4786	Flagellar basal body rod
ACRYA_RS01635	COG1815	bacterial-type flagellum-dependent cell motility
ACRYA_RS01640	COG1766	The M ring may be actively involved in energy transduction
ACRYA_RS01645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACRYA_RS01655	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACRYA_RS01665	COG1749	Flagellar hook protein flgE
ACRYA_RS01670	COG1749	Flagellar hook protein flgE
ACRYA_RS01695	COG3951	Flagellar rod assembly protein muramidase FlgJ
ACRYA_RS01710	COG1419	protein localization to endoplasmic reticulum
ACRYA_RS01715	COG0455	bacterial-type flagellum organization
ACRYA_RS01725	COG1677	Flagellar hook-basal body complex protein FliE
ACRYA_RS01745	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACRYA_RS01755	COG1157	protein secretion by the type III secretion system
ACRYA_RS01765	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACRYA_RS01775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACRYA_RS01790	COG0840	transmembrane signaling receptor activity
ACRYA_RS01795	COG0840	transmembrane signaling receptor activity
ACRYA_RS01810	COG3300	MHYT domain
ACRYA_RS01810	COG5001	Diguanylate cyclase
ACRYA_RS01815	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACRYA_RS01825	COG0336	Belongs to the RNA methyltransferase TrmD family
ACRYA_RS01830	COG0335	large ribosomal subunit rRNA binding
ACRYA_RS01835	COG0586	Pfam SNARE associated Golgi protein
ACRYA_RS01840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACRYA_RS01855	COG0251	oxidation-reduction process
ACRYA_RS01860	COG3610	response to peptide
ACRYA_RS01865	COG2966	Psort location CytoplasmicMembrane, score
ACRYA_RS01880	COG0811	peptide transport
ACRYA_RS01885	COG0848	biopolymer transport protein
ACRYA_RS01910	COG1971	Probably functions as a manganese efflux pump
ACRYA_RS01920	COG0659	secondary active sulfate transmembrane transporter activity
ACRYA_RS01935	COG0628	permease
ACRYA_RS01945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACRYA_RS01950	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACRYA_RS01955	COG4773	Receptor
ACRYA_RS01960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACRYA_RS01965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACRYA_RS01975	COG0142	geranyltranstransferase activity
ACRYA_RS01980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACRYA_RS01985	COG0442	prolyl-tRNA aminoacylation
ACRYA_RS01990	COG0668	transmembrane transport
ACRYA_RS02000	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACRYA_RS02005	COG1862	Preprotein translocase
ACRYA_RS02010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACRYA_RS02015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACRYA_RS02025	COG1360	Flagellar Motor Protein
ACRYA_RS02030	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACRYA_RS02040	COG0495	leucyl-tRNA aminoacylation
ACRYA_RS02050	COG0285	dihydrofolate synthase activity
ACRYA_RS02070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACRYA_RS02100	COG1396	sequence-specific DNA binding
ACRYA_RS02125	COG2911	Protein conserved in bacteria
ACRYA_RS02130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACRYA_RS02135	COG0444	Belongs to the ABC transporter superfamily
ACRYA_RS02140	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACRYA_RS02145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACRYA_RS02175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACRYA_RS02180	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACRYA_RS02195	COG0250	Participates in transcription elongation, termination and antitermination
ACRYA_RS02200	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACRYA_RS02205	COG0081	regulation of translation
ACRYA_RS02210	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACRYA_RS02215	COG0222	ribosome binding
ACRYA_RS02220	COG0085	RNA polymerase activity
ACRYA_RS02225	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACRYA_RS02240	COG0582	viral genome integration into host DNA
ACRYA_RS02365	COG1278	Cold shock
ACRYA_RS02370	COG0450	alkyl hydroperoxide reductase
ACRYA_RS02375	COG3118	belongs to the thioredoxin family
ACRYA_RS02390	COG0386	Belongs to the glutathione peroxidase family
ACRYA_RS02395	COG0300	oxidoreductase activity
ACRYA_RS02400	COG2211	Major facilitator Superfamily
ACRYA_RS02415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACRYA_RS02425	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ACRYA_RS02430	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ACRYA_RS02435	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ACRYA_RS02450	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ACRYA_RS02465	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ACRYA_RS02470	COG0298	carbon dioxide binding
ACRYA_RS02485	COG2084	Dehydrogenase
ACRYA_RS02495	COG0309	Hydrogenase expression formation protein (HypE)
ACRYA_RS02510	COG0310	cobalt ion transport
ACRYA_RS02555	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACRYA_RS02565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACRYA_RS02575	COG1295	ribonuclease BN
ACRYA_RS02580	COG0277	FAD linked oxidase domain protein
ACRYA_RS02590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACRYA_RS02595	COG2226	methyltransferase
ACRYA_RS02600	COG0196	riboflavin kinase activity
ACRYA_RS02610	COG1739	Uncharacterized protein family UPF0029
ACRYA_RS02630	COG0483	inositol monophosphate 1-phosphatase activity
ACRYA_RS02635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACRYA_RS02690	COG1216	Glycosyl transferase, family 2
ACRYA_RS02695	COG0438	transferase activity, transferring glycosyl groups
ACRYA_RS02700	COG0859	PFAM glycosyl transferase family 9
ACRYA_RS02720	COG0859	PFAM glycosyl transferase family 9
ACRYA_RS02730	COG0859	PFAM glycosyl transferase family 9
ACRYA_RS02735	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACRYA_RS02740	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACRYA_RS02740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACRYA_RS02750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACRYA_RS02760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACRYA_RS02770	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACRYA_RS02785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACRYA_RS02795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACRYA_RS02845	COG1136	(ABC) transporter
ACRYA_RS02870	COG1408	metallophosphoesterase
ACRYA_RS02875	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS02885	COG1121	(ABC) transporter
ACRYA_RS02890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACRYA_RS02895	COG2996	Protein conserved in bacteria
ACRYA_RS02900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ACRYA_RS02920	COG0525	valine-tRNA ligase activity
ACRYA_RS02935	COG2814	Major facilitator Superfamily
ACRYA_RS02940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACRYA_RS02960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACRYA_RS02965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACRYA_RS02970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACRYA_RS02995	COG0439	Biotin carboxylase
ACRYA_RS03005	COG2166	iron-sulfur cluster assembly
ACRYA_RS03010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACRYA_RS03020	COG0396	ATPase activity
ACRYA_RS03025	COG0719	Fe-S assembly protein
ACRYA_RS03035	COG2239	Acts as a magnesium transporter
ACRYA_RS03040	COG3706	GGDEF domain
ACRYA_RS03045	COG0165	Argininosuccinate lyase
ACRYA_RS03050	COG0556	nucleotide-excision repair
ACRYA_RS03060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACRYA_RS03065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACRYA_RS03070	COG0784	Response regulator, receiver
ACRYA_RS03070	COG0835	chemotaxis
ACRYA_RS03085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACRYA_RS03090	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACRYA_RS03095	COG0585	pseudouridine synthase activity
ACRYA_RS03105	COG0840	transmembrane signaling receptor activity
ACRYA_RS03110	COG0632	four-way junction helicase activity
ACRYA_RS03115	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACRYA_RS03125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACRYA_RS03140	COG0051	transcription antitermination factor activity, RNA binding
ACRYA_RS03145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACRYA_RS03150	COG0088	Forms part of the polypeptide exit tunnel
ACRYA_RS03155	COG0089	rRNA binding
ACRYA_RS03160	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACRYA_RS03165	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACRYA_RS03170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACRYA_RS03175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACRYA_RS03180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACRYA_RS03185	COG0255	Belongs to the universal ribosomal protein uL29 family
ACRYA_RS03190	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACRYA_RS03195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACRYA_RS03200	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACRYA_RS03205	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACRYA_RS03210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACRYA_RS03215	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACRYA_RS03220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACRYA_RS03225	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACRYA_RS03230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACRYA_RS03235	COG0200	Binds to the 23S rRNA
ACRYA_RS03240	COG0201	protein transport
ACRYA_RS03245	COG0024	Methionine aminopeptidase
ACRYA_RS03250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACRYA_RS03255	COG1573	uracil-dna glycosylase
ACRYA_RS03265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACRYA_RS03270	COG1032	radical SAM domain protein
ACRYA_RS03280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACRYA_RS03295	COG1131	(ABC) transporter
ACRYA_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
ACRYA_RS03325	COG2986	histidine ammonia-lyase
ACRYA_RS03345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACRYA_RS03350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACRYA_RS03355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACRYA_RS03370	COG2267	carboxylic ester hydrolase activity
ACRYA_RS03375	COG0500	methyltransferase
ACRYA_RS03390	COG2204	response regulator
ACRYA_RS03400	COG2203	Gaf domain
ACRYA_RS03400	COG3706	GGDEF domain
ACRYA_RS03400	COG4251	negative regulation of phosphorylation
ACRYA_RS03400	COG5001	Diguanylate cyclase
ACRYA_RS03425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACRYA_RS03430	COG0012	GTP binding
ACRYA_RS03435	COG1639	'signal transduction protein
ACRYA_RS03465	COG0730	response to heat
ACRYA_RS03470	COG1045	serine acetyltransferase
ACRYA_RS03475	COG1166	arginine decarboxylase activity
ACRYA_RS03480	COG0124	histidyl-tRNA synthetase
ACRYA_RS03485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACRYA_RS03490	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACRYA_RS03495	COG0163	prenyltransferase activity
ACRYA_RS03505	COG0359	binds to the 23S rRNA
ACRYA_RS03510	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACRYA_RS03515	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ACRYA_RS03525	COG0084	hydrolase, TatD family'
ACRYA_RS03535	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACRYA_RS03540	COG0131	Imidazoleglycerol-phosphate dehydratase
ACRYA_RS03545	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACRYA_RS03560	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACRYA_RS03565	COG0456	acetyltransferase
ACRYA_RS03575	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACRYA_RS03585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACRYA_RS03590	COG0328	RNA-DNA hybrid ribonuclease activity
ACRYA_RS03595	COG0840	transmembrane signaling receptor activity
ACRYA_RS03610	COG0513	Belongs to the DEAD box helicase family
ACRYA_RS03615	COG2217	Heavy metal translocating P-type atpase
ACRYA_RS03625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACRYA_RS03630	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACRYA_RS03635	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACRYA_RS03645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACRYA_RS03650	COG0488	(ABC) transporter
ACRYA_RS03655	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACRYA_RS03665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACRYA_RS03675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACRYA_RS03685	COG0849	cell division
ACRYA_RS03690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACRYA_RS03705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACRYA_RS03715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACRYA_RS03765	COG0582	viral genome integration into host DNA
ACRYA_RS03785	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ACRYA_RS03805	COG1132	(ABC) transporter
ACRYA_RS03810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ACRYA_RS03855	COG1216	Glycosyl transferase, family 2
ACRYA_RS03865	COG0438	transferase activity, transferring glycosyl groups
ACRYA_RS03880	COG0438	transferase activity, transferring glycosyl groups
ACRYA_RS03885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACRYA_RS03900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACRYA_RS03920	COG0166	Belongs to the GPI family
ACRYA_RS03935	COG1671	Belongs to the UPF0178 family
ACRYA_RS03965	COG0113	porphobilinogen synthase activity
ACRYA_RS03970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACRYA_RS03975	COG0357	Ribosomal RNA small subunit methyltransferase G
ACRYA_RS03995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACRYA_RS04000	COG0066	3-isopropylmalate dehydratase activity
ACRYA_RS04005	COG0473	3-isopropylmalate dehydrogenase activity
ACRYA_RS04020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACRYA_RS04025	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACRYA_RS04030	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACRYA_RS04035	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACRYA_RS04040	COG0202	RNA polymerase activity
ACRYA_RS04045	COG0203	ribosomal protein L17
ACRYA_RS04050	COG0154	amidase activity
ACRYA_RS04055	COG0517	IMP dehydrogenase activity
ACRYA_RS04055	COG0516	GMP reductase activity
ACRYA_RS04060	COG0840	transmembrane signaling receptor activity
ACRYA_RS04065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACRYA_RS04070	COG0840	transmembrane signaling receptor activity
ACRYA_RS04075	COG0754	glutathionylspermidine amidase activity
ACRYA_RS04085	COG0513	Belongs to the DEAD box helicase family
ACRYA_RS04100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACRYA_RS04110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACRYA_RS04115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACRYA_RS04125	COG0788	formyltetrahydrofolate deformylase activity
ACRYA_RS04135	COG1114	Component of the transport system for branched-chain amino acids
ACRYA_RS04160	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS04165	COG5002	protein histidine kinase activity
ACRYA_RS04190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACRYA_RS04200	COG1696	Membrane protein involved in D-alanine export
ACRYA_RS04205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACRYA_RS04235	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACRYA_RS04240	COG0352	thiamine-phosphate diphosphorylase activity
ACRYA_RS04240	COG0351	phosphomethylpyrimidine kinase
ACRYA_RS04260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACRYA_RS04265	COG1611	Belongs to the LOG family
ACRYA_RS04285	COG0217	transcriptional regulatory protein
ACRYA_RS04290	COG1132	(ABC) transporter
ACRYA_RS04300	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS04305	COG0642	Histidine kinase
ACRYA_RS04315	COG0840	transmembrane signaling receptor activity
ACRYA_RS04325	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACRYA_RS04330	COG0750	zinc metalloprotease
ACRYA_RS04335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACRYA_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
ACRYA_RS04345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACRYA_RS04355	COG0167	dihydroorotate dehydrogenase activity
ACRYA_RS04360	COG1132	(ABC) transporter
ACRYA_RS04365	COG0728	peptidoglycan biosynthetic process
ACRYA_RS04375	COG0735	belongs to the Fur family
ACRYA_RS04380	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACRYA_RS04390	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACRYA_RS04395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACRYA_RS04395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACRYA_RS04410	COG1233	COG1233 Phytoene dehydrogenase and related
ACRYA_RS04415	COG3275	phosphorelay sensor kinase activity
ACRYA_RS04420	COG3279	Response regulator of the LytR AlgR family
ACRYA_RS04425	COG2200	EAL domain
ACRYA_RS04435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACRYA_RS04450	COG3046	protein related to deoxyribodipyrimidine photolyase
ACRYA_RS04455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACRYA_RS04460	COG3040	lipid binding
ACRYA_RS04470	COG1090	epimerase
ACRYA_RS04475	COG0415	Belongs to the DNA photolyase family
ACRYA_RS04505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACRYA_RS04510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACRYA_RS04515	COG2199	diguanylate cyclase activity
ACRYA_RS04515	COG2200	EAL domain
ACRYA_RS04515	COG3287	FIST C domain
ACRYA_RS04530	COG0596	Alpha beta hydrolase
ACRYA_RS04550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACRYA_RS04550	COG0519	Catalyzes the synthesis of GMP from XMP
ACRYA_RS04555	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACRYA_RS04565	COG1451	nucleotide metabolic process
ACRYA_RS04605	COG0475	glutathione-regulated potassium exporter activity
ACRYA_RS04605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACRYA_RS04615	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACRYA_RS04640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACRYA_RS04645	COG1187	pseudouridine synthase activity
ACRYA_RS04650	COG0546	phosphoglycolate phosphatase activity
ACRYA_RS04665	COG4771	TonB-dependent receptor
ACRYA_RS04670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACRYA_RS04680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACRYA_RS04700	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACRYA_RS04710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACRYA_RS04715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACRYA_RS04725	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACRYA_RS04735	COG0653	protein targeting
ACRYA_RS04740	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACRYA_RS04755	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACRYA_RS04760	COG1333	cytochrome c biogenesis protein
ACRYA_RS04760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACRYA_RS04770	COG0500	methyltransferase
ACRYA_RS04775	COG4251	negative regulation of phosphorylation
ACRYA_RS04775	COG5001	Diguanylate cyclase
ACRYA_RS04775	COG2203	Gaf domain
ACRYA_RS04775	COG3706	GGDEF domain
ACRYA_RS04785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACRYA_RS04810	COG0484	heat shock protein binding
ACRYA_RS04815	COG0582	viral genome integration into host DNA
ACRYA_RS04820	COG2201	protein-glutamate methylesterase activity
ACRYA_RS04825	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ACRYA_RS04830	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACRYA_RS04835	COG0643	Histidine kinase
ACRYA_RS04835	COG2198	Histidine kinase
ACRYA_RS04840	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS04845	COG1185	polyribonucleotide nucleotidyltransferase activity
ACRYA_RS04855	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ACRYA_RS04875	COG0659	secondary active sulfate transmembrane transporter activity
ACRYA_RS04880	COG1160	GTP binding
ACRYA_RS04885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACRYA_RS04895	COG1674	ftsk spoiiie
ACRYA_RS04895	COG1196	nuclear chromosome segregation
ACRYA_RS04900	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACRYA_RS04905	COG0440	acetolactate synthase activity
ACRYA_RS04910	COG0028	Belongs to the TPP enzyme family
ACRYA_RS04945	COG0037	tRNA processing
ACRYA_RS04965	COG2321	neutral zinc metallopeptidase
ACRYA_RS04975	COG0501	Belongs to the peptidase M48B family
ACRYA_RS04980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACRYA_RS04985	COG0824	Thioesterase
ACRYA_RS04990	COG5001	Diguanylate cyclase
ACRYA_RS04990	COG3706	GGDEF domain
ACRYA_RS04990	COG2203	Gaf domain
ACRYA_RS04990	COG4251	negative regulation of phosphorylation
ACRYA_RS05005	COG0339	signal peptide processing
ACRYA_RS05010	COG2890	protein-(glutamine-N5) methyltransferase activity
ACRYA_RS05015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACRYA_RS05020	COG0494	nUDIX hydrolase
ACRYA_RS05025	COG0527	aspartate kinase activity
ACRYA_RS05040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACRYA_RS05060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACRYA_RS05065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACRYA_RS05075	COG3135	benzoate transporter
ACRYA_RS05085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACRYA_RS05090	COG2258	MOSC domain
ACRYA_RS05100	COG1119	ATPase activity
ACRYA_RS05110	COG1253	flavin adenine dinucleotide binding
ACRYA_RS05115	COG1193	negative regulation of DNA recombination
ACRYA_RS05125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACRYA_RS05135	COG0039	L-malate dehydrogenase activity
ACRYA_RS05165	COG0275	rRNA processing
ACRYA_RS05175	COG0776	regulation of translation
ACRYA_RS05190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACRYA_RS05190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ACRYA_RS05195	COG2201	protein-glutamate methylesterase activity
ACRYA_RS05210	COG0484	heat shock protein binding
ACRYA_RS05215	COG0789	Transcriptional regulator
ACRYA_RS05220	COG0861	Integral membrane protein TerC family
ACRYA_RS05225	COG1663	tetraacyldisaccharide 4'-kinase activity
ACRYA_RS05230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACRYA_RS05235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACRYA_RS05260	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ACRYA_RS05265	COG0805	protein transport
ACRYA_RS05270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACRYA_RS05275	COG0667	Aldo Keto reductase
ACRYA_RS05295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACRYA_RS05300	COG0488	(ABC) transporter
ACRYA_RS05310	COG0739	heme binding
ACRYA_RS05320	COG2199	diguanylate cyclase activity
ACRYA_RS05325	COG1942	4-Oxalocrotonate Tautomerase
ACRYA_RS05330	COG0134	indole-3-glycerol-phosphate synthase activity
ACRYA_RS05340	COG0727	PFAM Uncharacterised protein family (UPF0153)
ACRYA_RS05345	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ACRYA_RS05355	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACRYA_RS05355	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACRYA_RS05360	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACRYA_RS05370	COG2176	DNA-directed DNA polymerase activity
ACRYA_RS05375	COG0135	phosphoribosylanthranilate isomerase activity
ACRYA_RS05380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACRYA_RS05395	COG1921	L-seryl-tRNASec selenium transferase activity
ACRYA_RS05405	COG0243	molybdopterin cofactor binding
ACRYA_RS05420	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACRYA_RS05425	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACRYA_RS05430	COG0612	Peptidase, M16
ACRYA_RS05435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACRYA_RS05460	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACRYA_RS05470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACRYA_RS05470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACRYA_RS05485	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ACRYA_RS05520	COG1666	GTP binding
ACRYA_RS05525	COG2363	Small membrane protein
ACRYA_RS05530	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ACRYA_RS05535	COG1049	propionate catabolic process, 2-methylcitrate cycle
ACRYA_RS05545	COG3258	Cytochrome c
ACRYA_RS05555	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS05560	COG0642	Histidine kinase
ACRYA_RS05565	COG2076	Multidrug Resistance protein
ACRYA_RS05575	COG1881	PFAM PEBP family protein
ACRYA_RS05600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACRYA_RS05615	COG2201	protein-glutamate methylesterase activity
ACRYA_RS05625	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ACRYA_RS05630	COG1137	ATPase activity
ACRYA_RS05635	COG0802	atpase or kinase
ACRYA_RS05640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACRYA_RS05650	COG0300	oxidoreductase activity
ACRYA_RS05670	COG0484	heat shock protein binding
ACRYA_RS05680	COG0840	transmembrane signaling receptor activity
ACRYA_RS05685	COG1607	acyl-coa hydrolase
ACRYA_RS05690	COG0488	(ABC) transporter
ACRYA_RS05700	COG0778	Nitroreductase
ACRYA_RS05705	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACRYA_RS05725	COG0552	protein localization to endoplasmic reticulum
ACRYA_RS05740	COG1418	mRNA catabolic process
ACRYA_RS05745	COG0742	ribosomal rna small subunit methyltransferase
ACRYA_RS05750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACRYA_RS05755	COG0137	argininosuccinate synthase activity
ACRYA_RS05770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACRYA_RS05780	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACRYA_RS05785	COG0159	tryptophan synthase activity
ACRYA_RS05790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACRYA_RS05795	COG2255	four-way junction helicase activity
ACRYA_RS05800	COG0628	permease
ACRYA_RS05840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACRYA_RS05845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACRYA_RS05845	COG2169	Transcriptional regulator
ACRYA_RS05855	COG2171	N-acyltransferase activity
ACRYA_RS05860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACRYA_RS05885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACRYA_RS05890	COG2081	HI0933 family
ACRYA_RS05895	COG0726	polysaccharide deacetylase
ACRYA_RS05900	COG2354	Protein conserved in bacteria
ACRYA_RS05910	COG2814	Major facilitator Superfamily
ACRYA_RS05930	COG4662	Binding-protein-dependent transport system inner membrane component
ACRYA_RS05935	COG2998	abc-type tungstate transport system, permease component
ACRYA_RS05940	COG0303	'Molybdopterin
ACRYA_RS05960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACRYA_RS05970	COG0437	4 iron, 4 sulfur cluster binding
ACRYA_RS06005	COG2204	response regulator
ACRYA_RS06020	COG1305	Transglutaminase-like
ACRYA_RS06025	COG0709	Synthesizes selenophosphate from selenide and ATP
ACRYA_RS06030	COG0210	DNA helicase
ACRYA_RS06035	COG0569	domain protein
ACRYA_RS06035	COG0475	glutathione-regulated potassium exporter activity
ACRYA_RS06040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACRYA_RS06120	COG3123	guanosine phosphorylase activity
ACRYA_RS06125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACRYA_RS06135	COG0772	Belongs to the SEDS family
ACRYA_RS06140	COG0564	pseudouridine synthase activity
ACRYA_RS06150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACRYA_RS06155	COG2884	Cell division ATP-binding protein ftsE
ACRYA_RS06175	COG0768	penicillin binding
ACRYA_RS06180	COG1338	Plays a role in the flagellum-specific transport system
ACRYA_RS06185	COG0784	Response regulator, receiver
ACRYA_RS06185	COG3437	response regulator, receiver
ACRYA_RS06195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACRYA_RS06210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACRYA_RS06220	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS06245	COG0322	excinuclease ABC activity
ACRYA_RS06250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACRYA_RS06255	COG1979	alcohol dehydrogenase
ACRYA_RS06270	COG2207	Transcriptional regulator
ACRYA_RS06275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ACRYA_RS06280	COG3706	GGDEF domain
ACRYA_RS06290	COG0563	adenylate kinase activity
ACRYA_RS06295	COG0563	adenylate kinase activity
ACRYA_RS06310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACRYA_RS06325	COG1966	Carbon starvation protein
ACRYA_RS06340	COG4771	TonB-dependent receptor
ACRYA_RS06345	COG0673	inositol 2-dehydrogenase activity
ACRYA_RS06360	COG0305	Participates in initiation and elongation during chromosome replication
ACRYA_RS06365	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACRYA_RS06380	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACRYA_RS06385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACRYA_RS06395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACRYA_RS06400	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACRYA_RS06405	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACRYA_RS06415	COG3706	GGDEF domain
ACRYA_RS06435	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACRYA_RS06445	COG0706	membrane insertase activity
ACRYA_RS06450	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACRYA_RS06460	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACRYA_RS06465	COG0542	response to heat
ACRYA_RS06470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACRYA_RS06540	COG3210	domain, Protein
ACRYA_RS06540	COG3210	domain, Protein
ACRYA_RS06545	COG2831	hemolysin activation secretion protein
ACRYA_RS06550	COG0577	efflux transmembrane transporter activity
ACRYA_RS06550	COG1136	(ABC) transporter
ACRYA_RS06570	COG0811	peptide transport
ACRYA_RS06575	COG0848	biopolymer transport protein
ACRYA_RS06590	COG1686	Belongs to the peptidase S11 family
ACRYA_RS06595	COG0459	protein refolding
ACRYA_RS06610	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACRYA_RS06615	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACRYA_RS06625	COG0835	chemotaxis
ACRYA_RS06630	COG1570	exodeoxyribonuclease VII activity
ACRYA_RS06650	COG1692	metallophosphoesterase
ACRYA_RS06655	COG5002	protein histidine kinase activity
ACRYA_RS06660	COG3920	Histidine kinase
ACRYA_RS06665	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS06670	COG0840	transmembrane signaling receptor activity
ACRYA_RS06675	COG2081	HI0933 family
ACRYA_RS06680	COG0642	Histidine kinase
ACRYA_RS06685	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS06695	COG5001	Diguanylate cyclase
ACRYA_RS06695	COG2203	Gaf domain
ACRYA_RS06695	COG3706	GGDEF domain
ACRYA_RS06695	COG4251	negative regulation of phosphorylation
ACRYA_RS06705	COG2204	response regulator
ACRYA_RS06715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ACRYA_RS06730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACRYA_RS06735	COG1116	anion transmembrane transporter activity
ACRYA_RS06750	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACRYA_RS06780	COG1858	cytochrome C peroxidase
ACRYA_RS06785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACRYA_RS06790	COG0768	penicillin binding
ACRYA_RS06795	COG0772	Belongs to the SEDS family
ACRYA_RS06805	COG1968	undecaprenyl-diphosphatase activity
ACRYA_RS06810	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACRYA_RS06820	COG0314	molybdopterin synthase activity
ACRYA_RS06830	COG0174	glutamine synthetase
ACRYA_RS06835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACRYA_RS06840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACRYA_RS06845	COG0284	orotidine-5'-phosphate decarboxylase activity
ACRYA_RS06900	COG3041	Addiction module toxin RelE StbE family
ACRYA_RS06970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACRYA_RS06975	COG2197	response regulator
ACRYA_RS07010	COG0708	Exodeoxyribonuclease III
ACRYA_RS07015	COG0301	tRNA thio-modification
ACRYA_RS07015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACRYA_RS07070	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ACRYA_RS07110	COG0606	chelatase, subunit chli
ACRYA_RS07115	COG0840	transmembrane signaling receptor activity
ACRYA_RS07120	COG0840	transmembrane signaling receptor activity
ACRYA_RS07130	COG0242	peptide deformylase activity
ACRYA_RS07135	COG0740	serine-type endopeptidase activity
ACRYA_RS07140	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACRYA_RS07145	COG2326	polyphosphate kinase activity
ACRYA_RS07170	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ACRYA_RS07175	COG1355	regulation of microtubule-based process
ACRYA_RS07195	COG3256	nitric oxide reductase
ACRYA_RS07200	COG2010	Cytochrome c
ACRYA_RS07205	COG2010	Cytochrome c
ACRYA_RS07210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACRYA_RS07220	COG0535	radical SAM domain protein
ACRYA_RS07230	COG1648	precorrin-2 dehydrogenase activity
ACRYA_RS07230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACRYA_RS07240	COG1648	precorrin-2 dehydrogenase activity
ACRYA_RS07240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACRYA_RS07245	COG1522	sequence-specific DNA binding
ACRYA_RS07260	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACRYA_RS07270	COG1278	Cold shock
ACRYA_RS07285	COG2217	Heavy metal translocating P-type atpase
ACRYA_RS07290	COG5002	protein histidine kinase activity
ACRYA_RS07290	COG5001	Diguanylate cyclase
ACRYA_RS07295	COG0194	GDP metabolic process
ACRYA_RS07305	COG1136	(ABC) transporter
ACRYA_RS07310	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACRYA_RS07315	COG0052	Belongs to the universal ribosomal protein uS2 family
ACRYA_RS07320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACRYA_RS07335	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACRYA_RS07340	COG0579	oxidoreductase
ACRYA_RS07395	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS07405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACRYA_RS07415	COG2176	DNA-directed DNA polymerase activity
ACRYA_RS07425	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACRYA_RS07445	COG2176	DNA-directed DNA polymerase activity
ACRYA_RS07455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACRYA_RS07460	COG0280	phosphate acetyltransferase
ACRYA_RS07465	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACRYA_RS07470	COG0616	signal peptide processing
ACRYA_RS07475	COG0402	S-adenosylhomocysteine deaminase activity
ACRYA_RS07480	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACRYA_RS07485	COG0006	proline dipeptidase activity
ACRYA_RS07490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACRYA_RS07495	COG0482	sulfurtransferase activity
ACRYA_RS07500	COG0482	sulfurtransferase activity
ACRYA_RS07510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACRYA_RS07530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACRYA_RS07535	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACRYA_RS07540	COG3706	GGDEF domain
ACRYA_RS07550	COG2095	MarC family integral membrane protein
ACRYA_RS07555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACRYA_RS07570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACRYA_RS07580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACRYA_RS07585	COG2264	protein methyltransferase activity
ACRYA_RS07590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACRYA_RS07600	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACRYA_RS07610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACRYA_RS07615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACRYA_RS07630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACRYA_RS07645	COG0840	transmembrane signaling receptor activity
ACRYA_RS07685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACRYA_RS07695	COG0133	tryptophan synthase activity
ACRYA_RS07700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACRYA_RS07705	COG1793	dna ligase
ACRYA_RS07710	COG0626	cystathionine gamma-synthase activity
ACRYA_RS07720	COG0456	acetyltransferase
ACRYA_RS07740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACRYA_RS07780	COG0528	UMP kinase activity
ACRYA_RS07785	COG1758	RNA polymerase activity
ACRYA_RS07790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACRYA_RS07795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACRYA_RS07805	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACRYA_RS07820	COG0193	aminoacyl-tRNA hydrolase activity
ACRYA_RS07825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACRYA_RS07830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACRYA_RS07835	COG0681	Belongs to the peptidase S26 family
ACRYA_RS07840	COG0698	ribose 5-phosphate isomerase
ACRYA_RS07880	COG3287	FIST C domain
ACRYA_RS07880	COG2200	EAL domain
ACRYA_RS07880	COG2199	diguanylate cyclase activity
ACRYA_RS07885	COG0259	pyridoxamine-phosphate oxidase activity
ACRYA_RS07890	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACRYA_RS07900	COG0513	Belongs to the DEAD box helicase family
ACRYA_RS07920	COG0326	Molecular chaperone. Has ATPase activity
ACRYA_RS07930	COG0010	Belongs to the arginase family
ACRYA_RS07940	COG4335	DNA alkylation repair
ACRYA_RS07945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACRYA_RS07955	COG2264	protein methyltransferase activity
ACRYA_RS07975	COG2995	paraquat-inducible protein a
ACRYA_RS07980	COG3008	intermembrane lipid transfer
ACRYA_RS07985	COG0753	catalase activity
ACRYA_RS08000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACRYA_RS08005	COG0668	transmembrane transport
ACRYA_RS08010	COG1227	inorganic diphosphatase activity
ACRYA_RS08025	COG1027	Aspartate ammonia-lyase
ACRYA_RS08030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACRYA_RS08035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACRYA_RS08040	COG1047	Peptidyl-prolyl cis-trans
ACRYA_RS08055	COG0823	Involved in the tonB-independent uptake of proteins
ACRYA_RS08065	COG0848	biopolymer transport protein
ACRYA_RS08070	COG0811	peptide transport
ACRYA_RS08075	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACRYA_RS08080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACRYA_RS08085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACRYA_RS08090	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACRYA_RS08095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACRYA_RS08100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACRYA_RS08110	COG1475	DNA binding
ACRYA_RS08115	COG1192	Involved in chromosome partitioning
ACRYA_RS08130	COG0840	transmembrane signaling receptor activity
ACRYA_RS08135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACRYA_RS08140	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACRYA_RS08145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACRYA_RS08150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACRYA_RS08155	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACRYA_RS08160	COG0358	DNA primase activity
ACRYA_RS08170	COG0571	ribonuclease III activity
ACRYA_RS08175	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACRYA_RS08185	COG2326	polyphosphate kinase activity
ACRYA_RS08200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACRYA_RS08225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACRYA_RS08235	COG0741	lytic transglycosylase activity
ACRYA_RS08235	COG0739	heme binding
ACRYA_RS08235	COG1196	nuclear chromosome segregation
ACRYA_RS08255	COG2183	response to ionizing radiation
ACRYA_RS08260	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ACRYA_RS08265	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRYA_RS08270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRYA_RS08275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRYA_RS08275	COG0649	NAD binding
ACRYA_RS08280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACRYA_RS08290	COG0372	Belongs to the citrate synthase family
ACRYA_RS08300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACRYA_RS08305	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACRYA_RS08310	COG0839	Belongs to the complex I subunit 6 family
ACRYA_RS08315	COG0713	ATP synthesis coupled electron transport
ACRYA_RS08320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACRYA_RS08330	COG1007	ATP synthesis coupled electron transport
ACRYA_RS08340	COG1053	succinate dehydrogenase
ACRYA_RS08345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACRYA_RS08365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACRYA_RS08370	COG0416	fatty acid biosynthetic process
ACRYA_RS08375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACRYA_RS08385	COG0105	UTP biosynthetic process
ACRYA_RS08395	COG0450	alkyl hydroperoxide reductase
ACRYA_RS08400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACRYA_RS08405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACRYA_RS08410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACRYA_RS08415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACRYA_RS08425	COG0181	hydroxymethylbilane synthase activity
ACRYA_RS08470	COG3278	Belongs to the heme-copper respiratory oxidase family
ACRYA_RS08475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACRYA_RS08480	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACRYA_RS08485	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACRYA_RS08500	COG1242	4 iron, 4 sulfur cluster binding
ACRYA_RS08505	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACRYA_RS08510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACRYA_RS08515	COG0492	ferredoxin-NADP+ reductase activity
ACRYA_RS08520	COG3118	belongs to the thioredoxin family
ACRYA_RS08525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACRYA_RS08550	COG0642	Histidine kinase
ACRYA_RS08555	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS08565	COG0129	dihydroxy-acid dehydratase activity
ACRYA_RS08595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACRYA_RS08615	COG0585	pseudouridine synthase activity
ACRYA_RS08630	COG0793	Belongs to the peptidase S41A family
ACRYA_RS08635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACRYA_RS08640	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACRYA_RS08645	COG0047	phosphoribosylformylglycinamidine synthase activity
ACRYA_RS08655	COG0204	Acyl-transferase
ACRYA_RS08660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACRYA_RS08665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACRYA_RS08670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACRYA_RS08675	COG0018	arginyl-trna synthetase
ACRYA_RS08685	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACRYA_RS08690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACRYA_RS08695	COG0126	phosphoglycerate kinase activity
ACRYA_RS08700	COG0149	triose-phosphate isomerase activity
ACRYA_RS08705	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACRYA_RS08710	COG0019	diaminopimelate decarboxylase activity
ACRYA_RS08715	COG0077	Prephenate dehydratase
ACRYA_RS08715	COG1605	Chorismate mutase
ACRYA_RS08720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACRYA_RS08725	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACRYA_RS08740	COG0424	maF-like protein
ACRYA_RS08750	COG0791	NLP P60 protein
ACRYA_RS08780	COG0189	ligase activity
ACRYA_RS08795	COG3287	FIST C domain
ACRYA_RS08795	COG2200	EAL domain
ACRYA_RS08795	COG2199	diguanylate cyclase activity
ACRYA_RS08800	COG0688	phosphatidylethanolamine metabolic process
ACRYA_RS08810	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACRYA_RS08820	COG0288	reversible hydration of carbon dioxide
ACRYA_RS08825	COG0156	8-amino-7-oxononanoate synthase activity
ACRYA_RS08830	COG0792	nuclease activity
ACRYA_RS08850	COG5002	protein histidine kinase activity
ACRYA_RS08855	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS08870	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACRYA_RS08905	COG1987	bacterial-type flagellum assembly
ACRYA_RS08915	COG1706	bacterial-type flagellum-dependent cell motility
ACRYA_RS08935	COG0004	ammonium transporteR
ACRYA_RS08940	COG0666	response to abiotic stimulus
ACRYA_RS08945	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACRYA_RS08975	COG2059	Chromate
ACRYA_RS08980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACRYA_RS08990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACRYA_RS09005	COG0840	transmembrane signaling receptor activity
ACRYA_RS09010	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACRYA_RS09055	COG2022	thiamine diphosphate biosynthetic process
ACRYA_RS09065	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACRYA_RS09065	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACRYA_RS09075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACRYA_RS09090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACRYA_RS09095	COG0575	Belongs to the CDS family
ACRYA_RS09120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACRYA_RS09125	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACRYA_RS09130	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACRYA_RS09135	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACRYA_RS09145	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACRYA_RS09155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACRYA_RS09160	COG1393	Belongs to the ArsC family
ACRYA_RS09165	COG2828	Protein conserved in bacteria
ACRYA_RS09170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACRYA_RS09180	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACRYA_RS09190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACRYA_RS09195	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACRYA_RS09205	COG0560	Phosphoserine phosphatase
ACRYA_RS09215	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACRYA_RS09220	COG0786	glutamate:sodium symporter activity
ACRYA_RS09235	COG0736	holo-[acyl-carrier-protein] synthase activity
ACRYA_RS09240	COG0601	transmembrane transport
ACRYA_RS09245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACRYA_RS09255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACRYA_RS09285	COG2824	Alkylphosphonate utilization operon protein PhnA
ACRYA_RS09290	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACRYA_RS09295	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACRYA_RS09300	COG0573	inorganic phosphate transmembrane transporter activity
ACRYA_RS09305	COG0581	inorganic phosphate transmembrane transporter activity
ACRYA_RS09310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACRYA_RS09325	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS09330	COG5002	protein histidine kinase activity
ACRYA_RS09335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACRYA_RS09340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACRYA_RS09345	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACRYA_RS09350	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ACRYA_RS09385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACRYA_RS09400	COG1854	S-ribosylhomocysteine lyase activity
ACRYA_RS09410	COG1686	Belongs to the peptidase S11 family
ACRYA_RS09420	COG5002	protein histidine kinase activity
ACRYA_RS09425	COG0646	methionine synthase
ACRYA_RS09425	COG1410	methionine synthase
ACRYA_RS09450	COG0140	phosphoribosyl-ATP diphosphatase activity
ACRYA_RS09450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACRYA_RS09465	COG0456	acetyltransferase
ACRYA_RS09470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACRYA_RS09475	COG1917	Cupin 2, conserved barrel domain protein
ACRYA_RS09480	COG0489	protein tyrosine kinase activity
ACRYA_RS09485	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACRYA_RS09495	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACRYA_RS09495	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACRYA_RS09505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACRYA_RS09510	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACRYA_RS09515	COG0268	Binds directly to 16S ribosomal RNA
ACRYA_RS09520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACRYA_RS09525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACRYA_RS09530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACRYA_RS09540	COG0540	Belongs to the ATCase OTCase family
ACRYA_RS09545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACRYA_RS09550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACRYA_RS09555	COG0505	Belongs to the CarA family
ACRYA_RS09565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACRYA_RS09570	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ACRYA_RS09575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACRYA_RS09585	COG1846	Transcriptional regulator
ACRYA_RS09605	COG4895	conserved protein (DUF2196)
ACRYA_RS09610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACRYA_RS09615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACRYA_RS09620	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACRYA_RS09625	COG0237	dephospho-CoA kinase activity
ACRYA_RS09635	COG0348	domain, Protein
ACRYA_RS09640	COG0504	CTP synthase activity
ACRYA_RS09645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACRYA_RS09645	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ACRYA_RS09665	COG0587	DNA-directed DNA polymerase activity
ACRYA_RS09670	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACRYA_RS09685	COG0315	cyclic pyranopterin monophosphate synthase activity
ACRYA_RS09690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACRYA_RS09695	COG0428	transporter
ACRYA_RS09750	COG0582	viral genome integration into host DNA
ACRYA_RS09760	COG0109	protoheme IX farnesyltransferase activity
ACRYA_RS09770	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACRYA_RS09775	COG0254	rRNA binding
ACRYA_RS09780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACRYA_RS09785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACRYA_RS09795	COG0436	Aminotransferase
ACRYA_RS09800	COG0460	homoserine dehydrogenase
ACRYA_RS09805	COG0564	pseudouridine synthase activity
ACRYA_RS09810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACRYA_RS09815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACRYA_RS09820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACRYA_RS09825	COG3047	cAMP biosynthetic process
ACRYA_RS09825	COG2885	chlorophyll binding
ACRYA_RS09835	COG4206	TonB-dependent receptor
ACRYA_RS09850	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS09870	COG0604	alcohol dehydrogenase
ACRYA_RS09875	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACRYA_RS09880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACRYA_RS09890	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACRYA_RS09890	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACRYA_RS09895	COG0511	ligase activity, forming carbon-carbon bonds
ACRYA_RS09900	COG0439	Biotin carboxylase
ACRYA_RS09905	COG0513	Belongs to the DEAD box helicase family
ACRYA_RS09910	COG0306	phosphate transporter
ACRYA_RS09920	COG0367	asparagine synthase
ACRYA_RS09930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACRYA_RS09935	COG1981	membrane
ACRYA_RS09940	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ACRYA_RS09940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACRYA_RS09945	COG1187	pseudouridine synthase activity
ACRYA_RS09950	COG0517	IMP dehydrogenase activity
ACRYA_RS09950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACRYA_RS09955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACRYA_RS09960	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACRYA_RS09965	COG0107	imidazoleglycerol-phosphate synthase activity
ACRYA_RS09980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACRYA_RS09985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACRYA_RS09990	COG0724	RNA recognition motif
ACRYA_RS09995	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS10000	COG0642	Histidine kinase
ACRYA_RS10020	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACRYA_RS10025	COG2353	YceI-like domain
ACRYA_RS10030	COG0133	tryptophan synthase activity
ACRYA_RS10045	COG1408	metallophosphoesterase
ACRYA_RS10050	COG0071	Belongs to the small heat shock protein (HSP20) family
ACRYA_RS10060	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACRYA_RS10065	COG4208	sulfate ABC transporter
ACRYA_RS10070	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACRYA_RS10080	COG2199	diguanylate cyclase activity
ACRYA_RS10080	COG2200	EAL domain
ACRYA_RS10080	COG3287	FIST C domain
ACRYA_RS10095	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACRYA_RS10105	COG1217	gtp-binding protein TYPA
ACRYA_RS10110	COG2391	methyltransferase activity
ACRYA_RS10115	COG0425	Belongs to the sulfur carrier protein TusA family
ACRYA_RS10130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACRYA_RS10160	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS10165	COG0642	Histidine kinase
ACRYA_RS10170	COG3437	response regulator, receiver
ACRYA_RS10170	COG0784	Response regulator, receiver
ACRYA_RS10175	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ACRYA_RS10180	COG2860	membrane
ACRYA_RS10190	COG0788	formyltetrahydrofolate deformylase activity
ACRYA_RS10195	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACRYA_RS10200	COG0420	3'-5' exonuclease activity
ACRYA_RS10205	COG0419	ATPase involved in DNA repair
ACRYA_RS10225	COG0084	hydrolase, TatD family'
ACRYA_RS10295	COG0745	RESPONSE REGULATOR receiver
ACRYA_RS10300	COG2205	protein histidine kinase activity
ACRYA_RS10330	COG0653	protein targeting
ACRYA_RS10410	COG0582	viral genome integration into host DNA
ACRYA_RS10425	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACRYA_RS10530	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACRYA_RS10555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACRYA_RS10560	COG1450	Type ii and iii secretion system protein
ACRYA_RS10590	COG1459	type II secretion system
ACRYA_RS10600	COG2165	general secretion pathway protein
ACRYA_RS10660	COG0305	Participates in initiation and elongation during chromosome replication
ACRYA_RS10670	COG1475	DNA binding
ACRYA_RS10675	COG1192	Involved in chromosome partitioning
ACRYA_RS10680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance