locus-tag	class	description
ADFLV_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADFLV_RS00010	COG0592	DNA-directed DNA polymerase activity
ADFLV_RS00015	COG0187	DNA topoisomerase II activity
ADFLV_RS00020	COG0492	ferredoxin-NADP+ reductase activity
ADFLV_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADFLV_RS00085	COG0582	viral genome integration into host DNA
ADFLV_RS00090	COG1238	metal cluster binding
ADFLV_RS00100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADFLV_RS00125	COG1053	succinate dehydrogenase
ADFLV_RS00130	COG0667	Aldo Keto reductase
ADFLV_RS00145	COG4208	sulfate ABC transporter
ADFLV_RS00160	COG0500	methyltransferase
ADFLV_RS00165	COG1120	ATPase activity
ADFLV_RS00185	COG3842	ATPase activity
ADFLV_RS00210	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ADFLV_RS00215	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ADFLV_RS00225	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ADFLV_RS00245	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ADFLV_RS00250	COG0633	Ferredoxin
ADFLV_RS00270	COG0716	FMN binding
ADFLV_RS00305	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ADFLV_RS00325	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ADFLV_RS00330	COG2249	NAD(P)H dehydrogenase (quinone) activity
ADFLV_RS00335	COG1733	regulation of RNA biosynthetic process
ADFLV_RS00355	COG0426	domain, Protein
ADFLV_RS00370	COG1280	lysine exporter protein (LysE YggA)
ADFLV_RS00390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADFLV_RS00425	COG0840	transmembrane signaling receptor activity
ADFLV_RS00430	COG0564	pseudouridine synthase activity
ADFLV_RS00435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADFLV_RS00440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADFLV_RS00445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADFLV_RS00475	COG2954	triphosphatase activity
ADFLV_RS00480	COG1151	hydroxylamine reductase activity
ADFLV_RS00495	COG2885	chlorophyll binding
ADFLV_RS00500	COG0052	Belongs to the universal ribosomal protein uS2 family
ADFLV_RS00505	COG0604	alcohol dehydrogenase
ADFLV_RS00510	COG1733	regulation of RNA biosynthetic process
ADFLV_RS00515	COG0390	transport system, permease component
ADFLV_RS00525	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ADFLV_RS00530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADFLV_RS00555	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADFLV_RS00560	COG1252	NADH dehydrogenase
ADFLV_RS00570	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS00575	COG3852	Histidine kinase
ADFLV_RS00580	COG1556	Lactate utilization protein
ADFLV_RS00585	COG1139	Iron-sulfur cluster binding protein
ADFLV_RS00590	COG0247	lactate metabolic process
ADFLV_RS00600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADFLV_RS00605	COG0511	ligase activity, forming carbon-carbon bonds
ADFLV_RS00610	COG0439	Biotin carboxylase
ADFLV_RS00615	COG0513	Belongs to the DEAD box helicase family
ADFLV_RS00620	COG0306	phosphate transporter
ADFLV_RS00630	COG0367	asparagine synthase
ADFLV_RS00640	COG0778	Nitroreductase
ADFLV_RS00645	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADFLV_RS00655	COG1053	succinate dehydrogenase
ADFLV_RS00665	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ADFLV_RS00675	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ADFLV_RS00675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ADFLV_RS00680	COG1187	pseudouridine synthase activity
ADFLV_RS00685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ADFLV_RS00685	COG0517	IMP dehydrogenase activity
ADFLV_RS00690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ADFLV_RS00695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADFLV_RS00700	COG0107	imidazoleglycerol-phosphate synthase activity
ADFLV_RS00715	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ADFLV_RS00720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADFLV_RS00725	COG0724	RNA recognition motif
ADFLV_RS00730	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS00735	COG0642	Histidine kinase
ADFLV_RS00770	COG0534	Mate efflux family protein
ADFLV_RS00775	COG0789	Transcriptional regulator
ADFLV_RS00780	COG1335	isochorismatase
ADFLV_RS00785	COG0460	homoserine dehydrogenase
ADFLV_RS00790	COG0436	Aminotransferase
ADFLV_RS00805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ADFLV_RS00810	COG0254	rRNA binding
ADFLV_RS00815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ADFLV_RS00905	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ADFLV_RS00915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ADFLV_RS00920	COG0237	dephospho-CoA kinase activity
ADFLV_RS00925	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ADFLV_RS00930	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ADFLV_RS00935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADFLV_RS00955	COG2353	YceI-like domain
ADFLV_RS00960	COG1846	Transcriptional regulator
ADFLV_RS00965	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ADFLV_RS00970	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ADFLV_RS00975	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADFLV_RS00985	COG0505	Belongs to the CarA family
ADFLV_RS00990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ADFLV_RS01000	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADFLV_RS01000	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ADFLV_RS01015	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ADFLV_RS01020	COG0489	protein tyrosine kinase activity
ADFLV_RS01030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ADFLV_RS01030	COG0140	phosphoribosyl-ATP diphosphatase activity
ADFLV_RS01050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADFLV_RS01060	COG1410	methionine synthase
ADFLV_RS01060	COG0646	methionine synthase
ADFLV_RS01065	COG0697	spore germination
ADFLV_RS01075	COG1979	alcohol dehydrogenase
ADFLV_RS01080	COG3647	Membrane
ADFLV_RS01095	COG1686	Belongs to the peptidase S11 family
ADFLV_RS01110	COG1854	S-ribosylhomocysteine lyase activity
ADFLV_RS01150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ADFLV_RS01175	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADFLV_RS01180	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADFLV_RS01190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADFLV_RS01195	COG0546	phosphoglycolate phosphatase activity
ADFLV_RS01205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ADFLV_RS01210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADFLV_RS01215	COG5002	protein histidine kinase activity
ADFLV_RS01230	COG0704	Plays a role in the regulation of phosphate uptake
ADFLV_RS01235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ADFLV_RS01240	COG0581	inorganic phosphate transmembrane transporter activity
ADFLV_RS01245	COG0573	inorganic phosphate transmembrane transporter activity
ADFLV_RS01250	COG2203	Gaf domain
ADFLV_RS01250	COG2200	EAL domain
ADFLV_RS01250	COG2199	diguanylate cyclase activity
ADFLV_RS01255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ADFLV_RS01265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADFLV_RS01270	COG0268	Binds directly to 16S ribosomal RNA
ADFLV_RS01275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADFLV_RS01285	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADFLV_RS01290	COG0746	molybdenum cofactor guanylyltransferase activity
ADFLV_RS01300	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADFLV_RS01305	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ADFLV_RS01310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADFLV_RS01315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADFLV_RS01345	COG0575	Belongs to the CDS family
ADFLV_RS01350	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ADFLV_RS01370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ADFLV_RS01375	COG0023	Translation Initiation Factor
ADFLV_RS01380	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADFLV_RS01380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADFLV_RS01385	COG1324	tolerance protein
ADFLV_RS01390	COG2022	thiamine diphosphate biosynthetic process
ADFLV_RS01415	COG0582	viral genome integration into host DNA
ADFLV_RS01505	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ADFLV_RS01555	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS01570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADFLV_RS01580	COG4191	Histidine kinase
ADFLV_RS01585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ADFLV_RS01595	COG2084	Dehydrogenase
ADFLV_RS01610	COG1346	cytolysis
ADFLV_RS01615	COG0640	Transcriptional regulator
ADFLV_RS01625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ADFLV_RS01630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADFLV_RS01645	COG1742	UPF0060 membrane protein
ADFLV_RS01650	COG0659	secondary active sulfate transmembrane transporter activity
ADFLV_RS01670	COG4589	Belongs to the CDS family
ADFLV_RS01690	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ADFLV_RS01715	COG0666	response to abiotic stimulus
ADFLV_RS01720	COG0004	ammonium transporteR
ADFLV_RS01730	COG0004	ammonium transporteR
ADFLV_RS01740	COG0418	dihydroorotase activity
ADFLV_RS01745	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADFLV_RS01750	COG1706	bacterial-type flagellum-dependent cell motility
ADFLV_RS01785	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ADFLV_RS01795	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ADFLV_RS01810	COG0037	tRNA processing
ADFLV_RS01815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADFLV_RS01820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADFLV_RS01825	COG0601	transmembrane transport
ADFLV_RS01835	COG0736	holo-[acyl-carrier-protein] synthase activity
ADFLV_RS01840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ADFLV_RS01850	COG0560	Phosphoserine phosphatase
ADFLV_RS01860	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ADFLV_RS01865	COG3248	Nucleoside-binding outer membrane protein
ADFLV_RS01875	COG1393	Belongs to the ArsC family
ADFLV_RS01880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADFLV_RS01885	COG0343	queuine tRNA-ribosyltransferase activity
ADFLV_RS01895	COG0436	Aminotransferase
ADFLV_RS01910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADFLV_RS01920	COG2861	carbohydrate metabolic process
ADFLV_RS01925	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADFLV_RS01930	COG0557	exoribonuclease II activity
ADFLV_RS01945	COG0360	Binds together with S18 to 16S ribosomal RNA
ADFLV_RS01950	COG0629	single-stranded DNA binding
ADFLV_RS01955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADFLV_RS01960	COG0215	cysteine-tRNA ligase activity
ADFLV_RS01965	COG0195	Participates in both transcription termination and antitermination
ADFLV_RS01975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADFLV_RS01980	COG2121	Domain of unknown function (DUF374)
ADFLV_RS01990	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ADFLV_RS02000	COG0288	reversible hydration of carbon dioxide
ADFLV_RS02005	COG0156	8-amino-7-oxononanoate synthase activity
ADFLV_RS02010	COG0792	nuclease activity
ADFLV_RS02040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADFLV_RS02050	COG0540	Belongs to the ATCase OTCase family
ADFLV_RS02055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADFLV_RS02075	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ADFLV_RS02080	COG1687	branched-chain amino acid
ADFLV_RS02085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADFLV_RS02090	COG0416	fatty acid biosynthetic process
ADFLV_RS02095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ADFLV_RS02105	COG0105	UTP biosynthetic process
ADFLV_RS02115	COG0450	alkyl hydroperoxide reductase
ADFLV_RS02120	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ADFLV_RS02130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADFLV_RS02135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ADFLV_RS02140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADFLV_RS02150	COG0181	hydroxymethylbilane synthase activity
ADFLV_RS02165	COG2828	Protein conserved in bacteria
ADFLV_RS02170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ADFLV_RS02180	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ADFLV_RS02190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADFLV_RS02225	COG2207	Transcriptional regulator
ADFLV_RS02225	COG3708	Transcriptional regulator
ADFLV_RS02230	COG0514	ATP-dependent DNA helicase (RecQ)
ADFLV_RS02240	COG0640	Transcriptional regulator
ADFLV_RS02245	COG2217	Heavy metal translocating P-type atpase
ADFLV_RS02260	COG1451	nucleotide metabolic process
ADFLV_RS02265	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ADFLV_RS02275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADFLV_RS02280	COG1053	succinate dehydrogenase
ADFLV_RS02290	COG1007	ATP synthesis coupled electron transport
ADFLV_RS02300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADFLV_RS02305	COG0713	ATP synthesis coupled electron transport
ADFLV_RS02310	COG0839	Belongs to the complex I subunit 6 family
ADFLV_RS02315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_RS02320	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADFLV_RS02325	COG1034	ATP synthesis coupled electron transport
ADFLV_RS02330	COG0372	Belongs to the citrate synthase family
ADFLV_RS02345	COG0649	NAD binding
ADFLV_RS02345	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_RS02350	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_RS02355	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_RS02360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ADFLV_RS02365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ADFLV_RS02370	COG3610	response to peptide
ADFLV_RS02375	COG2966	Psort location CytoplasmicMembrane, score
ADFLV_RS02385	COG0863	Belongs to the N(4) N(6)-methyltransferase family
ADFLV_RS02405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ADFLV_RS02415	COG3706	GGDEF domain
ADFLV_RS02440	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADFLV_RS02460	COG0840	transmembrane signaling receptor activity
ADFLV_RS02480	COG3043	anaerobic respiration
ADFLV_RS02485	COG0348	domain, Protein
ADFLV_RS02490	COG0437	4 iron, 4 sulfur cluster binding
ADFLV_RS02495	COG0243	molybdopterin cofactor binding
ADFLV_RS02500	COG3287	FIST C domain
ADFLV_RS02500	COG2199	diguanylate cyclase activity
ADFLV_RS02500	COG2200	EAL domain
ADFLV_RS02505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADFLV_RS02520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADFLV_RS02525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADFLV_RS02530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ADFLV_RS02540	COG2404	hydrolase activity, acting on ester bonds
ADFLV_RS02545	COG1832	CoA-binding protein
ADFLV_RS02550	COG0642	Histidine kinase
ADFLV_RS02555	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS02560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADFLV_RS02565	COG0191	fructose-bisphosphate aldolase activity
ADFLV_RS02570	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS02575	COG0642	Histidine kinase
ADFLV_RS02595	COG0811	peptide transport
ADFLV_RS02605	COG4191	Histidine kinase
ADFLV_RS02620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADFLV_RS02630	COG0142	geranyltranstransferase activity
ADFLV_RS02635	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ADFLV_RS02640	COG0442	prolyl-tRNA aminoacylation
ADFLV_RS02645	COG0668	transmembrane transport
ADFLV_RS02665	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ADFLV_RS02670	COG1862	Preprotein translocase
ADFLV_RS02675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADFLV_RS02680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADFLV_RS02695	COG0495	leucyl-tRNA aminoacylation
ADFLV_RS02705	COG0285	dihydrofolate synthase activity
ADFLV_RS02740	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ADFLV_RS02760	COG4399	Belongs to the UPF0754 family
ADFLV_RS02775	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ADFLV_RS02790	COG3292	Two component regulator propeller
ADFLV_RS02790	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS02790	COG2205	protein histidine kinase activity
ADFLV_RS02800	COG3706	GGDEF domain
ADFLV_RS02800	COG2203	Gaf domain
ADFLV_RS02800	COG4251	negative regulation of phosphorylation
ADFLV_RS02800	COG5001	Diguanylate cyclase
ADFLV_RS02810	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS02815	COG0642	Histidine kinase
ADFLV_RS02820	COG2081	HI0933 family
ADFLV_RS02825	COG0840	transmembrane signaling receptor activity
ADFLV_RS02835	COG0840	transmembrane signaling receptor activity
ADFLV_RS02845	COG1692	metallophosphoesterase
ADFLV_RS02860	COG2226	methyltransferase
ADFLV_RS02865	COG1570	exodeoxyribonuclease VII activity
ADFLV_RS02880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADFLV_RS02890	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ADFLV_RS02895	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ADFLV_RS02905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ADFLV_RS02910	COG0459	protein refolding
ADFLV_RS02915	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ADFLV_RS02925	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS02930	COG1408	metallophosphoesterase
ADFLV_RS02955	COG1136	(ABC) transporter
ADFLV_RS02970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADFLV_RS02990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ADFLV_RS02995	COG0352	thiamine-phosphate diphosphorylase activity
ADFLV_RS03000	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ADFLV_RS03010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADFLV_RS03015	COG2264	protein methyltransferase activity
ADFLV_RS03020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADFLV_RS03025	COG0784	Response regulator, receiver
ADFLV_RS03025	COG3437	response regulator, receiver
ADFLV_RS03035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADFLV_RS03055	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ADFLV_RS03085	COG1132	(ABC) transporter
ADFLV_RS03100	COG3706	GGDEF domain
ADFLV_RS03105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ADFLV_RS03110	COG1090	epimerase
ADFLV_RS03115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADFLV_RS03125	COG0481	GTPase activity
ADFLV_RS03140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADFLV_RS03150	COG0482	sulfurtransferase activity
ADFLV_RS03155	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ADFLV_RS03160	COG0006	proline dipeptidase activity
ADFLV_RS03165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ADFLV_RS03170	COG0402	S-adenosylhomocysteine deaminase activity
ADFLV_RS03175	COG0616	signal peptide processing
ADFLV_RS03185	COG0280	phosphate acetyltransferase
ADFLV_RS03190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADFLV_RS03195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADFLV_RS03200	COG2176	DNA-directed DNA polymerase activity
ADFLV_RS03220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADFLV_RS03230	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ADFLV_RS03240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADFLV_RS03250	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS03300	COG1058	Belongs to the CinA family
ADFLV_RS03300	COG1546	Belongs to the CinA family
ADFLV_RS03305	COG0579	oxidoreductase
ADFLV_RS03310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ADFLV_RS03325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADFLV_RS03355	COG0714	Associated with various cellular activities
ADFLV_RS03360	COG0052	Belongs to the universal ribosomal protein uS2 family
ADFLV_RS03365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ADFLV_RS03370	COG1136	(ABC) transporter
ADFLV_RS03380	COG0194	GDP metabolic process
ADFLV_RS03385	COG5001	Diguanylate cyclase
ADFLV_RS03385	COG5002	protein histidine kinase activity
ADFLV_RS03390	COG2217	Heavy metal translocating P-type atpase
ADFLV_RS03405	COG4608	Belongs to the ABC transporter superfamily
ADFLV_RS03410	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ADFLV_RS03425	COG1355	regulation of microtubule-based process
ADFLV_RS03435	COG1121	(ABC) transporter
ADFLV_RS03440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ADFLV_RS03455	COG2996	Protein conserved in bacteria
ADFLV_RS03460	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ADFLV_RS03465	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ADFLV_RS03475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ADFLV_RS03485	COG0210	DNA helicase
ADFLV_RS03490	COG0475	glutathione-regulated potassium exporter activity
ADFLV_RS03490	COG0569	domain protein
ADFLV_RS03495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ADFLV_RS03520	COG3258	Cytochrome c
ADFLV_RS03560	COG0693	protein deglycase activity
ADFLV_RS03580	COG0525	valine-tRNA ligase activity
ADFLV_RS03585	COG4895	conserved protein (DUF2196)
ADFLV_RS03590	COG1047	Peptidyl-prolyl cis-trans
ADFLV_RS03600	COG3706	GGDEF domain
ADFLV_RS03610	COG2814	Major facilitator Superfamily
ADFLV_RS03615	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADFLV_RS03625	COG2197	response regulator
ADFLV_RS03635	COG2831	hemolysin activation secretion protein
ADFLV_RS03655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADFLV_RS03660	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADFLV_RS03665	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADFLV_RS03685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADFLV_RS03695	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ADFLV_RS03700	COG1309	transcriptional regulator
ADFLV_RS03725	COG0840	transmembrane signaling receptor activity
ADFLV_RS03740	COG0439	Biotin carboxylase
ADFLV_RS03745	COG3040	lipid binding
ADFLV_RS03775	COG2151	metal-sulfur cluster biosynthetic enzyme
ADFLV_RS03780	COG2166	iron-sulfur cluster assembly
ADFLV_RS03785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ADFLV_RS03795	COG0396	ATPase activity
ADFLV_RS03800	COG0719	Fe-S assembly protein
ADFLV_RS03805	COG4191	Histidine kinase
ADFLV_RS03810	COG1366	Belongs to the anti-sigma-factor antagonist family
ADFLV_RS03810	COG2202	Pas domain
ADFLV_RS03820	COG0822	iron-sulfur transferase activity
ADFLV_RS03820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ADFLV_RS03820	COG2906	2 iron, 2 sulfur cluster binding
ADFLV_RS03825	COG1280	lysine exporter protein (LysE YggA)
ADFLV_RS03840	COG2239	Acts as a magnesium transporter
ADFLV_RS03850	COG3706	GGDEF domain
ADFLV_RS03870	COG0165	Argininosuccinate lyase
ADFLV_RS03875	COG0784	Response regulator, receiver
ADFLV_RS03875	COG0835	chemotaxis
ADFLV_RS03880	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ADFLV_RS03885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADFLV_RS03900	COG0556	nucleotide-excision repair
ADFLV_RS03905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADFLV_RS03915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ADFLV_RS03940	COG0698	ribose 5-phosphate isomerase
ADFLV_RS03945	COG0681	Belongs to the peptidase S26 family
ADFLV_RS03950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADFLV_RS03955	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ADFLV_RS03960	COG0193	aminoacyl-tRNA hydrolase activity
ADFLV_RS03975	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADFLV_RS03985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADFLV_RS03995	COG1758	RNA polymerase activity
ADFLV_RS04000	COG0528	UMP kinase activity
ADFLV_RS04010	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ADFLV_RS04015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ADFLV_RS04020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADFLV_RS04030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADFLV_RS04035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADFLV_RS04050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ADFLV_RS04060	COG0305	Participates in initiation and elongation during chromosome replication
ADFLV_RS04075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ADFLV_RS04115	COG1011	Hydrolase
ADFLV_RS04130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADFLV_RS04175	COG2337	Toxic component of a toxin-antitoxin (TA) module
ADFLV_RS04185	COG4115	mRNA cleavage
ADFLV_RS04190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADFLV_RS04200	COG1086	Polysaccharide biosynthesis protein
ADFLV_RS04210	COG1793	dna ligase
ADFLV_RS04215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADFLV_RS04220	COG0133	tryptophan synthase activity
ADFLV_RS04230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ADFLV_RS04235	COG0848	biopolymer transport protein
ADFLV_RS04260	COG0577	efflux transmembrane transporter activity
ADFLV_RS04260	COG1136	(ABC) transporter
ADFLV_RS04265	COG1136	(ABC) transporter
ADFLV_RS04265	COG0577	efflux transmembrane transporter activity
ADFLV_RS04320	COG0114	fumarate hydratase activity
ADFLV_RS04350	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADFLV_RS04350	COG1918	ferrous iron import across plasma membrane
ADFLV_RS04355	COG1918	ferrous iron import across plasma membrane
ADFLV_RS04365	COG4771	TonB-dependent receptor
ADFLV_RS04370	COG2819	hydrolase of the alpha beta superfamily
ADFLV_RS04375	COG3920	Histidine kinase
ADFLV_RS04380	COG0784	Response regulator, receiver
ADFLV_RS04385	COG4771	TonB-dependent receptor
ADFLV_RS04400	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS04425	COG0012	GTP binding
ADFLV_RS04445	COG3123	guanosine phosphorylase activity
ADFLV_RS04470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ADFLV_RS04475	COG0585	pseudouridine synthase activity
ADFLV_RS04485	COG4773	Receptor
ADFLV_RS04490	COG0840	transmembrane signaling receptor activity
ADFLV_RS04495	COG0632	four-way junction helicase activity
ADFLV_RS04500	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADFLV_RS04510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADFLV_RS04525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADFLV_RS04530	COG0051	transcription antitermination factor activity, RNA binding
ADFLV_RS04535	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADFLV_RS04540	COG0088	Forms part of the polypeptide exit tunnel
ADFLV_RS04545	COG0089	rRNA binding
ADFLV_RS04550	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADFLV_RS04555	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADFLV_RS04560	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ADFLV_RS04565	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADFLV_RS04570	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADFLV_RS04575	COG0255	Belongs to the universal ribosomal protein uL29 family
ADFLV_RS04580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADFLV_RS04585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADFLV_RS04590	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADFLV_RS04595	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADFLV_RS04600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADFLV_RS04605	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADFLV_RS04610	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADFLV_RS04615	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADFLV_RS04620	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADFLV_RS04625	COG0200	Binds to the 23S rRNA
ADFLV_RS04630	COG0201	protein transport
ADFLV_RS04635	COG0024	Methionine aminopeptidase
ADFLV_RS04640	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADFLV_RS04650	COG1573	uracil-dna glycosylase
ADFLV_RS04660	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ADFLV_RS04675	COG1032	radical SAM domain protein
ADFLV_RS04685	COG0563	adenylate kinase activity
ADFLV_RS04700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADFLV_RS04705	COG0322	excinuclease ABC activity
ADFLV_RS04715	COG3706	GGDEF domain
ADFLV_RS04725	COG3201	nicotinamide mononucleotide transporter
ADFLV_RS04730	COG0386	Belongs to the glutathione peroxidase family
ADFLV_RS04745	COG0840	transmembrane signaling receptor activity
ADFLV_RS04750	COG0840	transmembrane signaling receptor activity
ADFLV_RS04760	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS04770	COG2205	protein histidine kinase activity
ADFLV_RS04770	COG0784	Response regulator, receiver
ADFLV_RS04800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADFLV_RS04810	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADFLV_RS04815	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ADFLV_RS04850	COG0829	nickel cation binding
ADFLV_RS04855	COG0402	S-adenosylhomocysteine deaminase activity
ADFLV_RS04860	COG2252	PERMEase
ADFLV_RS04875	COG4266	Belongs to the allantoicase family
ADFLV_RS04890	COG2351	hydroxyisourate hydrolase activity
ADFLV_RS04900	COG2233	PERMEase
ADFLV_RS04925	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ADFLV_RS04925	COG3608	succinylglutamate desuccinylase aspartoacylase
ADFLV_RS04930	COG0832	Belongs to the urease beta subunit family
ADFLV_RS04930	COG0831	urea catabolic process
ADFLV_RS04935	COG0804	urea catabolic process
ADFLV_RS04940	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ADFLV_RS04950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ADFLV_RS04970	COG1846	Transcriptional regulator
ADFLV_RS04980	COG3706	GGDEF domain
ADFLV_RS04985	COG0708	Exodeoxyribonuclease III
ADFLV_RS05020	COG0166	Belongs to the GPI family
ADFLV_RS05065	COG2252	PERMEase
ADFLV_RS05070	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ADFLV_RS05080	COG2363	Small membrane protein
ADFLV_RS05090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ADFLV_RS05095	COG2233	PERMEase
ADFLV_RS05100	COG1666	GTP binding
ADFLV_RS05110	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS05115	COG0642	Histidine kinase
ADFLV_RS05135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADFLV_RS05140	COG0135	phosphoribosylanthranilate isomerase activity
ADFLV_RS05145	COG2176	DNA-directed DNA polymerase activity
ADFLV_RS05150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADFLV_RS05160	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADFLV_RS05165	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADFLV_RS05165	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADFLV_RS05175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ADFLV_RS05180	COG0727	PFAM Uncharacterised protein family (UPF0153)
ADFLV_RS05190	COG0134	indole-3-glycerol-phosphate synthase activity
ADFLV_RS05195	COG0583	DNA-binding transcription factor activity
ADFLV_RS05205	COG0840	transmembrane signaling receptor activity
ADFLV_RS05215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ADFLV_RS05220	COG0750	zinc metalloprotease
ADFLV_RS05225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADFLV_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
ADFLV_RS05235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADFLV_RS05250	COG0167	dihydroorotate dehydrogenase activity
ADFLV_RS05255	COG1132	(ABC) transporter
ADFLV_RS05260	COG0728	peptidoglycan biosynthetic process
ADFLV_RS05270	COG1592	Rubrerythrin
ADFLV_RS05280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ADFLV_RS05285	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ADFLV_RS05325	COG1858	cytochrome C peroxidase
ADFLV_RS05340	COG0552	protein localization to endoplasmic reticulum
ADFLV_RS05345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADFLV_RS05355	COG1418	mRNA catabolic process
ADFLV_RS05360	COG0742	ribosomal rna small subunit methyltransferase
ADFLV_RS05365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADFLV_RS05375	COG0300	oxidoreductase activity
ADFLV_RS05385	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ADFLV_RS05390	COG0732	type I restriction modification DNA specificity domain
ADFLV_RS05410	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ADFLV_RS05415	COG3258	Cytochrome c
ADFLV_RS05430	COG0642	Histidine kinase
ADFLV_RS05445	COG1610	YqeY-like protein
ADFLV_RS05455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ADFLV_RS05460	COG0436	Aminotransferase
ADFLV_RS05465	COG1451	nucleotide metabolic process
ADFLV_RS05475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ADFLV_RS05480	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ADFLV_RS05485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADFLV_RS05485	COG0519	Catalyzes the synthesis of GMP from XMP
ADFLV_RS05535	COG0697	spore germination
ADFLV_RS05555	COG0596	Alpha beta hydrolase
ADFLV_RS05560	COG0204	Acyl-transferase
ADFLV_RS05570	COG0531	amino acid
ADFLV_RS05590	COG1696	Membrane protein involved in D-alanine export
ADFLV_RS05595	COG0564	pseudouridine synthase activity
ADFLV_RS05700	COG1393	Belongs to the ArsC family
ADFLV_RS05710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADFLV_RS05715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADFLV_RS05720	COG2223	nitrite transmembrane transporter activity
ADFLV_RS05725	COG2186	Transcriptional regulator
ADFLV_RS05730	COG2807	transmembrane transport
ADFLV_RS05745	COG1028	Short-chain dehydrogenase reductase Sdr
ADFLV_RS05750	COG0519	Catalyzes the synthesis of GMP from XMP
ADFLV_RS05750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADFLV_RS05785	COG1253	flavin adenine dinucleotide binding
ADFLV_RS05790	COG2989	Protein conserved in bacteria
ADFLV_RS05800	COG0628	permease
ADFLV_RS05815	COG1253	flavin adenine dinucleotide binding
ADFLV_RS05830	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADFLV_RS05870	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADFLV_RS05875	COG0513	Belongs to the DEAD box helicase family
ADFLV_RS05880	COG2200	EAL domain
ADFLV_RS05880	COG2199	diguanylate cyclase activity
ADFLV_RS05880	COG3287	FIST C domain
ADFLV_RS05885	COG0840	transmembrane signaling receptor activity
ADFLV_RS05890	COG0840	transmembrane signaling receptor activity
ADFLV_RS05905	COG1045	serine acetyltransferase
ADFLV_RS05910	COG1166	arginine decarboxylase activity
ADFLV_RS05915	COG0124	histidyl-tRNA synthetase
ADFLV_RS05920	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADFLV_RS05925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ADFLV_RS05930	COG0163	prenyltransferase activity
ADFLV_RS05940	COG0359	binds to the 23S rRNA
ADFLV_RS05945	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ADFLV_RS05950	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ADFLV_RS05960	COG0084	hydrolase, TatD family'
ADFLV_RS05970	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ADFLV_RS05975	COG0131	Imidazoleglycerol-phosphate dehydratase
ADFLV_RS05980	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ADFLV_RS05995	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ADFLV_RS06000	COG0456	acetyltransferase
ADFLV_RS06010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADFLV_RS06020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADFLV_RS06025	COG3576	pyridoxamine 5-phosphate
ADFLV_RS06045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADFLV_RS06055	COG2897	thiosulfate sulfurtransferase activity
ADFLV_RS06065	COG1338	Plays a role in the flagellum-specific transport system
ADFLV_RS06125	COG0849	cell division
ADFLV_RS06130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADFLV_RS06135	COG2391	methyltransferase activity
ADFLV_RS06160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADFLV_RS06180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ADFLV_RS06185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ADFLV_RS06275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADFLV_RS06320	COG3505	Type IV secretory pathway VirD4
ADFLV_RS06335	COG3504	Conjugal transfer protein
ADFLV_RS06530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ADFLV_RS06545	COG1401	restriction endodeoxyribonuclease activity
ADFLV_RS06555	COG1401	restriction endodeoxyribonuclease activity
ADFLV_RS06610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADFLV_RS06640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADFLV_RS06700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ADFLV_RS06705	COG4974	Belongs to the 'phage' integrase family
ADFLV_RS06720	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ADFLV_RS06740	COG2026	Addiction module toxin, RelE StbE family
ADFLV_RS06770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ADFLV_RS06775	COG1360	Flagellar Motor Protein
ADFLV_RS06780	COG0861	Integral membrane protein TerC family
ADFLV_RS06825	COG0842	Transport permease protein
ADFLV_RS06830	COG0842	Transport permease protein
ADFLV_RS06835	COG1131	(ABC) transporter
ADFLV_RS06840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADFLV_RS06845	COG0789	Transcriptional regulator
ADFLV_RS06850	COG0484	heat shock protein binding
ADFLV_RS06855	COG4191	Histidine kinase
ADFLV_RS06865	COG2201	protein-glutamate methylesterase activity
ADFLV_RS06875	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ADFLV_RS06875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADFLV_RS06890	COG0776	regulation of translation
ADFLV_RS06900	COG0275	rRNA processing
ADFLV_RS06930	COG0318	PFAM AMP-dependent synthetase and ligase
ADFLV_RS06940	COG4865	methylaspartate mutase activity
ADFLV_RS06950	COG0039	L-malate dehydrogenase activity
ADFLV_RS06970	COG4591	ABC-type transport system involved in lipoprotein release permease component
ADFLV_RS06975	COG0653	protein targeting
ADFLV_RS06990	COG2207	Transcriptional regulator
ADFLV_RS06995	COG1979	alcohol dehydrogenase
ADFLV_RS07005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADFLV_RS07005	COG4191	Histidine kinase
ADFLV_RS07010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADFLV_RS07010	COG1587	Uroporphyrinogen-III synthase
ADFLV_RS07020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ADFLV_RS07025	COG0243	molybdopterin cofactor binding
ADFLV_RS07030	COG2200	EAL domain
ADFLV_RS07030	COG3287	FIST C domain
ADFLV_RS07030	COG2199	diguanylate cyclase activity
ADFLV_RS07035	COG2815	serine threonine protein kinase
ADFLV_RS07035	COG0515	serine threonine protein kinase
ADFLV_RS07040	COG2223	nitrite transmembrane transporter activity
ADFLV_RS07045	COG0754	glutathionylspermidine amidase activity
ADFLV_RS07055	COG3706	GGDEF domain
ADFLV_RS07060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ADFLV_RS07090	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS07100	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS07195	COG4804	nuclease activity
ADFLV_RS07245	COG0640	Transcriptional regulator
ADFLV_RS07355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADFLV_RS07370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADFLV_RS07385	COG0281	malic enzyme
ADFLV_RS07385	COG0280	phosphate acetyltransferase
ADFLV_RS07390	COG0788	formyltetrahydrofolate deformylase activity
ADFLV_RS07395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ADFLV_RS07410	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS07420	COG0330	HflC and HflK could
ADFLV_RS07440	COG1271	oxidase subunit
ADFLV_RS07465	COG0450	alkyl hydroperoxide reductase
ADFLV_RS07480	COG0811	peptide transport
ADFLV_RS07485	COG0848	biopolymer transport protein
ADFLV_RS07500	COG0419	ATPase involved in DNA repair
ADFLV_RS07530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ADFLV_RS07535	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ADFLV_RS07540	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ADFLV_RS07545	COG1187	pseudouridine synthase activity
ADFLV_RS07575	COG4206	TonB-dependent receptor
ADFLV_RS07590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADFLV_RS07615	COG0667	Aldo Keto reductase
ADFLV_RS07620	COG0840	transmembrane signaling receptor activity
ADFLV_RS07635	COG0824	Thioesterase
ADFLV_RS07645	COG0501	Belongs to the peptidase M48B family
ADFLV_RS07650	COG1322	Protein conserved in bacteria
ADFLV_RS07660	COG2321	neutral zinc metallopeptidase
ADFLV_RS07685	COG0037	tRNA processing
ADFLV_RS07690	COG1683	Conserved Protein
ADFLV_RS07710	COG5001	Diguanylate cyclase
ADFLV_RS07710	COG4251	negative regulation of phosphorylation
ADFLV_RS07710	COG3706	GGDEF domain
ADFLV_RS07710	COG2203	Gaf domain
ADFLV_RS07730	COG0028	Belongs to the TPP enzyme family
ADFLV_RS07735	COG0440	acetolactate synthase activity
ADFLV_RS07740	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADFLV_RS07745	COG1196	nuclear chromosome segregation
ADFLV_RS07745	COG1674	ftsk spoiiie
ADFLV_RS07755	COG1160	GTP binding
ADFLV_RS07760	COG0659	secondary active sulfate transmembrane transporter activity
ADFLV_RS07780	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ADFLV_RS07790	COG1185	polyribonucleotide nucleotidyltransferase activity
ADFLV_RS07800	COG0643	Histidine kinase
ADFLV_RS07800	COG2198	Histidine kinase
ADFLV_RS07805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ADFLV_RS07810	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ADFLV_RS07815	COG2201	protein-glutamate methylesterase activity
ADFLV_RS07825	COG0582	viral genome integration into host DNA
ADFLV_RS07845	COG0339	signal peptide processing
ADFLV_RS07850	COG2890	protein-(glutamine-N5) methyltransferase activity
ADFLV_RS07855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADFLV_RS07860	COG0494	nUDIX hydrolase
ADFLV_RS07865	COG0527	aspartate kinase activity
ADFLV_RS07880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADFLV_RS07885	COG0287	Prephenate dehydrogenase
ADFLV_RS07890	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADFLV_RS07895	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ADFLV_RS07900	COG0612	Peptidase, M16
ADFLV_RS07905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADFLV_RS07935	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ADFLV_RS07945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADFLV_RS07945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADFLV_RS07970	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ADFLV_RS07975	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ADFLV_RS08030	COG4974	Belongs to the 'phage' integrase family
ADFLV_RS08095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADFLV_RS08125	COG0357	Ribosomal RNA small subunit methyltransferase G
ADFLV_RS08130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADFLV_RS08135	COG0113	porphobilinogen synthase activity
ADFLV_RS08160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADFLV_RS08160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADFLV_RS08165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADFLV_RS08170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADFLV_RS08180	COG1663	tetraacyldisaccharide 4'-kinase activity
ADFLV_RS08190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ADFLV_RS08210	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ADFLV_RS08215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADFLV_RS08220	COG0805	protein transport
ADFLV_RS08225	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ADFLV_RS08260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ADFLV_RS08275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ADFLV_RS08295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADFLV_RS08295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADFLV_RS08300	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ADFLV_RS08305	COG2200	EAL domain
ADFLV_RS08305	COG3287	FIST C domain
ADFLV_RS08305	COG2199	diguanylate cyclase activity
ADFLV_RS08310	COG3706	GGDEF domain
ADFLV_RS08315	COG1137	ATPase activity
ADFLV_RS08320	COG0802	atpase or kinase
ADFLV_RS08325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADFLV_RS08335	COG0137	argininosuccinate synthase activity
ADFLV_RS08345	COG0189	ligase activity
ADFLV_RS08365	COG0569	domain protein
ADFLV_RS08370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADFLV_RS08375	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS08380	COG2205	protein histidine kinase activity
ADFLV_RS08390	COG4191	Histidine kinase
ADFLV_RS08400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADFLV_RS08410	COG0484	heat shock protein binding
ADFLV_RS08415	COG0133	tryptophan synthase activity
ADFLV_RS08435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADFLV_RS08440	COG5001	Diguanylate cyclase
ADFLV_RS08445	COG2203	Gaf domain
ADFLV_RS08445	COG3706	GGDEF domain
ADFLV_RS08445	COG4251	negative regulation of phosphorylation
ADFLV_RS08445	COG5001	Diguanylate cyclase
ADFLV_RS08450	COG0500	methyltransferase
ADFLV_RS08455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADFLV_RS08455	COG1333	cytochrome c biogenesis protein
ADFLV_RS08460	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS08470	COG2195	Cleaves the N-terminal amino acid of tripeptides
ADFLV_RS08480	COG0840	transmembrane signaling receptor activity
ADFLV_RS08485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADFLV_RS08490	COG2205	protein histidine kinase activity
ADFLV_RS08490	COG4999	Histidine kinase
ADFLV_RS08490	COG3437	response regulator, receiver
ADFLV_RS08490	COG3850	Histidine kinase
ADFLV_RS08495	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS08500	COG3437	response regulator, receiver
ADFLV_RS08500	COG0784	Response regulator, receiver
ADFLV_RS08505	COG1607	acyl-coa hydrolase
ADFLV_RS08510	COG0488	(ABC) transporter
ADFLV_RS08520	COG1979	alcohol dehydrogenase
ADFLV_RS08525	COG2207	Transcriptional regulator
ADFLV_RS08530	COG3706	GGDEF domain
ADFLV_RS08535	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS08540	COG0643	Histidine kinase
ADFLV_RS08540	COG2198	Histidine kinase
ADFLV_RS08550	COG2205	protein histidine kinase activity
ADFLV_RS08565	COG3710	Transcriptional regulator
ADFLV_RS08570	COG0778	Nitroreductase
ADFLV_RS08590	COG2249	NAD(P)H dehydrogenase (quinone) activity
ADFLV_RS08595	COG1733	regulation of RNA biosynthetic process
ADFLV_RS08610	COG2855	membrane
ADFLV_RS08615	COG0583	DNA-binding transcription factor activity
ADFLV_RS08620	COG3706	GGDEF domain
ADFLV_RS08625	COG1881	PFAM PEBP family protein
ADFLV_RS08635	COG3706	GGDEF domain
ADFLV_RS08650	COG2076	Multidrug Resistance protein
ADFLV_RS08685	COG2824	Alkylphosphonate utilization operon protein PhnA
ADFLV_RS08695	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ADFLV_RS08700	COG0095	Lipoate-protein ligase
ADFLV_RS08705	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ADFLV_RS08710	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADFLV_RS08715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADFLV_RS08775	COG1605	Chorismate mutase
ADFLV_RS08775	COG0077	Prephenate dehydratase
ADFLV_RS08780	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADFLV_RS08785	COG1119	ATPase activity
ADFLV_RS08790	COG0784	Response regulator, receiver
ADFLV_RS08790	COG2205	protein histidine kinase activity
ADFLV_RS08795	COG2205	protein histidine kinase activity
ADFLV_RS08795	COG2202	Pas domain
ADFLV_RS08800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADFLV_RS08820	COG1193	negative regulation of DNA recombination
ADFLV_RS08830	COG0471	metal ion transport
ADFLV_RS08835	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADFLV_RS08845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADFLV_RS08850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADFLV_RS08860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADFLV_RS08890	COG2274	protein secretion by the type I secretion system
ADFLV_RS08900	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS08915	COG0513	Belongs to the DEAD box helicase family
ADFLV_RS08925	COG3706	GGDEF domain
ADFLV_RS08930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ADFLV_RS08940	COG3279	Response regulator of the LytR AlgR family
ADFLV_RS08955	COG1233	COG1233 Phytoene dehydrogenase and related
ADFLV_RS08995	COG0642	Histidine kinase
ADFLV_RS09000	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS09020	COG1132	(ABC) transporter
ADFLV_RS09025	COG0628	permease
ADFLV_RS09030	COG1472	Belongs to the glycosyl hydrolase 3 family
ADFLV_RS09055	COG1620	l-lactate permease
ADFLV_RS09070	COG0484	heat shock protein binding
ADFLV_RS09120	COG0517	IMP dehydrogenase activity
ADFLV_RS09120	COG0516	GMP reductase activity
ADFLV_RS09125	COG0154	amidase activity
ADFLV_RS09130	COG0203	ribosomal protein L17
ADFLV_RS09135	COG0202	RNA polymerase activity
ADFLV_RS09140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADFLV_RS09145	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ADFLV_RS09150	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ADFLV_RS09155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ADFLV_RS09170	COG0473	3-isopropylmalate dehydrogenase activity
ADFLV_RS09245	COG3504	Conjugal transfer protein
ADFLV_RS09260	COG3505	Type IV secretory pathway VirD4
ADFLV_RS09305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADFLV_RS09385	COG0066	3-isopropylmalate dehydratase activity
ADFLV_RS09390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADFLV_RS09410	COG3123	guanosine phosphorylase activity
ADFLV_RS09415	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ADFLV_RS09430	COG0772	Belongs to the SEDS family
ADFLV_RS09435	COG0564	pseudouridine synthase activity
ADFLV_RS09440	COG3103	Sh3 type 3 domain protein
ADFLV_RS09440	COG0366	Alpha amylase catalytic
ADFLV_RS09445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ADFLV_RS09450	COG2884	Cell division ATP-binding protein ftsE
ADFLV_RS09465	COG1671	Belongs to the UPF0178 family
ADFLV_RS09475	COG0488	(ABC) transporter
ADFLV_RS09480	COG2171	N-acyltransferase activity
ADFLV_RS09485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADFLV_RS09510	COG3706	GGDEF domain
ADFLV_RS09520	COG0309	Hydrogenase expression formation protein (HypE)
ADFLV_RS09540	COG0298	carbon dioxide binding
ADFLV_RS09545	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ADFLV_RS09560	COG0840	transmembrane signaling receptor activity
ADFLV_RS09570	COG2081	HI0933 family
ADFLV_RS09585	COG0439	Biotin carboxylase
ADFLV_RS09615	COG2354	Protein conserved in bacteria
ADFLV_RS09625	COG2814	Major facilitator Superfamily
ADFLV_RS09645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ADFLV_RS09645	COG0301	tRNA thio-modification
ADFLV_RS09670	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ADFLV_RS09695	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ADFLV_RS09705	COG1518	maintenance of DNA repeat elements
ADFLV_RS09760	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ADFLV_RS09765	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ADFLV_RS09775	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ADFLV_RS09790	COG1049	propionate catabolic process, 2-methylcitrate cycle
ADFLV_RS09805	COG0242	peptide deformylase activity
ADFLV_RS09810	COG1022	Amp-dependent synthetase and ligase
ADFLV_RS09815	COG0183	Belongs to the thiolase family
ADFLV_RS09820	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADFLV_RS09820	COG1024	Enoyl-CoA hydratase
ADFLV_RS09825	COG1960	acyl-CoA dehydrogenase activity
ADFLV_RS09885	COG0217	transcriptional regulatory protein
ADFLV_RS09890	COG2853	Lipoprotein
ADFLV_RS09905	COG1611	Belongs to the LOG family
ADFLV_RS09910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADFLV_RS09915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADFLV_RS09935	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ADFLV_RS09950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ADFLV_RS09960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ADFLV_RS09965	COG0477	Major facilitator Superfamily
ADFLV_RS09985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADFLV_RS09985	COG0475	glutathione-regulated potassium exporter activity
ADFLV_RS09995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADFLV_RS10000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADFLV_RS10000	COG2169	Transcriptional regulator
ADFLV_RS10090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADFLV_RS10095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADFLV_RS10100	COG2258	MOSC domain
ADFLV_RS10120	COG0513	Belongs to the DEAD box helicase family
ADFLV_RS10150	COG1944	ATP diphosphatase activity
ADFLV_RS10170	COG0840	transmembrane signaling receptor activity
ADFLV_RS10175	COG0328	RNA-DNA hybrid ribonuclease activity
ADFLV_RS10180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADFLV_RS10205	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADFLV_RS10235	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS10285	COG5001	Diguanylate cyclase
ADFLV_RS10285	COG5002	protein histidine kinase activity
ADFLV_RS10300	COG1078	dGTPase activity
ADFLV_RS10305	COG0259	pyridoxamine-phosphate oxidase activity
ADFLV_RS10315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADFLV_RS10325	COG0513	Belongs to the DEAD box helicase family
ADFLV_RS10340	COG2200	EAL domain
ADFLV_RS10340	COG3287	FIST C domain
ADFLV_RS10340	COG2199	diguanylate cyclase activity
ADFLV_RS10350	COG1984	allophanate hydrolase subunit 2
ADFLV_RS10360	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ADFLV_RS10385	COG0842	Transport permease protein
ADFLV_RS10390	COG0842	Transport permease protein
ADFLV_RS10390	COG1129	ABC transporter
ADFLV_RS10395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADFLV_RS10400	COG1309	transcriptional regulator
ADFLV_RS10405	COG0306	phosphate transporter
ADFLV_RS10415	COG0326	Molecular chaperone. Has ATPase activity
ADFLV_RS10420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ADFLV_RS10450	COG2995	paraquat-inducible protein a
ADFLV_RS10465	COG5001	Diguanylate cyclase
ADFLV_RS10465	COG5002	protein histidine kinase activity
ADFLV_RS10485	COG2902	Dehydrogenase
ADFLV_RS10495	COG4335	DNA alkylation repair
ADFLV_RS10530	COG0010	Belongs to the arginase family
ADFLV_RS10535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADFLV_RS10540	COG2207	Transcriptional regulator
ADFLV_RS10560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADFLV_RS10565	COG1227	inorganic diphosphatase activity
ADFLV_RS10580	COG1027	Aspartate ammonia-lyase
ADFLV_RS10585	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS10595	COG1115	amino acid carrier protein
ADFLV_RS10600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ADFLV_RS10605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ADFLV_RS10610	COG1047	Peptidyl-prolyl cis-trans
ADFLV_RS10625	COG2193	ferroxidase activity
ADFLV_RS10630	COG0823	Involved in the tonB-independent uptake of proteins
ADFLV_RS10640	COG0848	biopolymer transport protein
ADFLV_RS10645	COG0811	peptide transport
ADFLV_RS10650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ADFLV_RS10655	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADFLV_RS10660	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADFLV_RS10665	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ADFLV_RS10670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADFLV_RS10675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADFLV_RS10685	COG1475	DNA binding
ADFLV_RS10690	COG1192	Involved in chromosome partitioning
ADFLV_RS10695	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ADFLV_RS10695	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ADFLV_RS10705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADFLV_RS10710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADFLV_RS10715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADFLV_RS10720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ADFLV_RS10725	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADFLV_RS10735	COG0358	DNA primase activity
ADFLV_RS10745	COG0571	ribonuclease III activity
ADFLV_RS10750	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ADFLV_RS10760	COG0501	Belongs to the peptidase M48B family
ADFLV_RS10780	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ADFLV_RS10790	COG0706	membrane insertase activity
ADFLV_RS10795	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ADFLV_RS10800	COG0594	ribonuclease P activity
ADFLV_RS10805	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ADFLV_RS10810	COG0542	response to heat
ADFLV_RS10825	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ADFLV_RS10840	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADFLV_RS10860	COG1120	ATPase activity
ADFLV_RS10895	COG0811	peptide transport
ADFLV_RS10900	COG0848	biopolymer transport protein
ADFLV_RS10915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADFLV_RS10920	COG3437	response regulator, receiver
ADFLV_RS10930	COG0784	Response regulator, receiver
ADFLV_RS10930	COG2205	protein histidine kinase activity
ADFLV_RS10935	COG0179	Fumarylacetoacetate (FAA) hydrolase
ADFLV_RS10965	COG0138	bifunctional purine biosynthesis protein purh
ADFLV_RS10970	COG0004	ammonium transporteR
ADFLV_RS10975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADFLV_RS10985	COG0741	lytic transglycosylase activity
ADFLV_RS10985	COG1196	nuclear chromosome segregation
ADFLV_RS10985	COG0739	heme binding
ADFLV_RS11000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADFLV_RS11015	COG0302	gtp cyclohydrolase
ADFLV_RS11020	COG0598	Magnesium transport protein CorA
ADFLV_RS11025	COG1459	type II secretion system
ADFLV_RS11045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ADFLV_RS11050	COG0606	chelatase, subunit chli
ADFLV_RS11060	COG0242	peptide deformylase activity
ADFLV_RS11065	COG0740	serine-type endopeptidase activity
ADFLV_RS11070	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADFLV_RS11095	COG1773	rubredoxin
ADFLV_RS11110	COG4974	Belongs to the 'phage' integrase family
ADFLV_RS11310	COG3501	Rhs element vgr protein
ADFLV_RS11390	COG0739	heme binding
ADFLV_RS11405	COG3501	Rhs element vgr protein
ADFLV_RS11430	COG3842	ATPase activity
ADFLV_RS11445	COG1177	transmembrane transport
ADFLV_RS11450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ADFLV_RS11470	COG0626	cystathionine gamma-synthase activity
ADFLV_RS11485	COG0840	transmembrane signaling receptor activity
ADFLV_RS11495	COG5002	protein histidine kinase activity
ADFLV_RS11500	COG0840	transmembrane signaling receptor activity
ADFLV_RS11505	COG0840	transmembrane signaling receptor activity
ADFLV_RS11515	COG0583	DNA-binding transcription factor activity
ADFLV_RS11540	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS11545	COG0456	acetyltransferase
ADFLV_RS11550	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ADFLV_RS11565	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADFLV_RS11575	COG2207	Transcriptional regulator
ADFLV_RS11580	COG0720	synthase
ADFLV_RS11585	COG0418	dihydroorotase activity
ADFLV_RS11595	COG1301	dicarboxylic acid transport
ADFLV_RS11600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADFLV_RS11615	COG1309	transcriptional regulator
ADFLV_RS11620	COG0840	transmembrane signaling receptor activity
ADFLV_RS11625	COG1028	Short-chain dehydrogenase reductase Sdr
ADFLV_RS11635	COG1858	cytochrome C peroxidase
ADFLV_RS11665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADFLV_RS11675	COG0668	transmembrane transport
ADFLV_RS11700	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADFLV_RS11715	COG0348	domain, Protein
ADFLV_RS11720	COG4191	Histidine kinase
ADFLV_RS11725	COG2207	Transcriptional regulator
ADFLV_RS11725	COG4753	response regulator
ADFLV_RS11735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADFLV_RS11740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ADFLV_RS11765	COG0716	FMN binding
ADFLV_RS11780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADFLV_RS11795	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ADFLV_RS11800	COG0159	tryptophan synthase activity
ADFLV_RS11805	COG0038	chloride channel
ADFLV_RS11810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ADFLV_RS11815	COG2255	four-way junction helicase activity
ADFLV_RS11820	COG0628	permease
ADFLV_RS11830	COG4628	conserved protein (DUF2132)
ADFLV_RS11885	COG0731	radical SAM domain protein
ADFLV_RS11890	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ADFLV_RS11900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADFLV_RS11915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADFLV_RS11925	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ADFLV_RS11935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ADFLV_RS11940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADFLV_RS11945	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ADFLV_RS11945	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ADFLV_RS11950	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ADFLV_RS11955	COG2990	Protein conserved in bacteria
ADFLV_RS11985	COG1696	Membrane protein involved in D-alanine export
ADFLV_RS12020	COG0438	transferase activity, transferring glycosyl groups
ADFLV_RS12025	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADFLV_RS12045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADFLV_RS12055	COG0493	'glutamate synthase
ADFLV_RS12060	COG0070	glutamate synthase
ADFLV_RS12060	COG0069	glutamate synthase activity
ADFLV_RS12060	COG0067	glutamate synthase
ADFLV_RS12070	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADFLV_RS12075	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADFLV_RS12090	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS12160	COG0284	orotidine-5'-phosphate decarboxylase activity
ADFLV_RS12165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADFLV_RS12170	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ADFLV_RS12175	COG3706	GGDEF domain
ADFLV_RS12180	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ADFLV_RS12205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ADFLV_RS12250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ADFLV_RS12310	COG1739	Uncharacterized protein family UPF0029
ADFLV_RS12320	COG0196	riboflavin kinase activity
ADFLV_RS12325	COG2226	methyltransferase
ADFLV_RS12330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADFLV_RS12340	COG0277	FAD linked oxidase domain protein
ADFLV_RS12350	COG5001	Diguanylate cyclase
ADFLV_RS12350	COG4251	negative regulation of phosphorylation
ADFLV_RS12350	COG3706	GGDEF domain
ADFLV_RS12350	COG2203	Gaf domain
ADFLV_RS12390	COG0542	response to heat
ADFLV_RS12395	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ADFLV_RS12400	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ADFLV_RS12415	COG2030	dehydratase
ADFLV_RS12440	COG1970	mechanosensitive ion channel activity
ADFLV_RS12445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADFLV_RS12475	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADFLV_RS12480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ADFLV_RS12485	COG1157	protein secretion by the type III secretion system
ADFLV_RS12495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADFLV_RS12515	COG1677	Flagellar hook-basal body complex protein FliE
ADFLV_RS12525	COG0455	bacterial-type flagellum organization
ADFLV_RS12530	COG1419	protein localization to endoplasmic reticulum
ADFLV_RS12560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADFLV_RS12580	COG1749	Flagellar hook protein flgE
ADFLV_RS12585	COG1749	Flagellar hook protein flgE
ADFLV_RS12595	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADFLV_RS12605	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADFLV_RS12610	COG1766	The M ring may be actively involved in energy transduction
ADFLV_RS12615	COG1815	bacterial-type flagellum-dependent cell motility
ADFLV_RS12620	COG4786	Flagellar basal body rod
ADFLV_RS12630	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS12650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADFLV_RS12660	COG0228	four-way junction DNA binding
ADFLV_RS12665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADFLV_RS12670	COG0564	pseudouridine synthase activity
ADFLV_RS12675	COG1519	Transferase
ADFLV_RS12685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ADFLV_RS12690	COG0752	glycyl-tRNA synthetase alpha subunit
ADFLV_RS12700	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADFLV_RS12715	COG0840	transmembrane signaling receptor activity
ADFLV_RS12715	COG0840	transmembrane signaling receptor activity
ADFLV_RS12720	COG0497	DNA recombination
ADFLV_RS12725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADFLV_RS12730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADFLV_RS12735	COG0049	tRNA binding
ADFLV_RS12740	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADFLV_RS12745	COG2814	Major facilitator Superfamily
ADFLV_RS12755	COG0840	transmembrane signaling receptor activity
ADFLV_RS12780	COG0310	cobalt ion transport
ADFLV_RS12800	COG0077	Prephenate dehydratase
ADFLV_RS12800	COG1605	Chorismate mutase
ADFLV_RS12835	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ADFLV_RS12860	COG0633	Ferredoxin
ADFLV_RS12860	COG0543	2 iron, 2 sulfur cluster binding
ADFLV_RS12865	COG0039	L-malate dehydrogenase activity
ADFLV_RS12875	COG0784	Response regulator, receiver
ADFLV_RS12890	COG0730	response to heat
ADFLV_RS12930	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS12935	COG0840	transmembrane signaling receptor activity
ADFLV_RS12940	COG1028	Short-chain dehydrogenase reductase Sdr
ADFLV_RS12945	COG0473	3-isopropylmalate dehydrogenase activity
ADFLV_RS12960	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADFLV_RS12965	COG0085	RNA polymerase activity
ADFLV_RS12970	COG0222	ribosome binding
ADFLV_RS12975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ADFLV_RS12980	COG0081	regulation of translation
ADFLV_RS12985	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADFLV_RS12990	COG0250	Participates in transcription elongation, termination and antitermination
ADFLV_RS13005	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ADFLV_RS13010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADFLV_RS13035	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADFLV_RS13040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADFLV_RS13045	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ADFLV_RS13050	COG0444	Belongs to the ABC transporter superfamily
ADFLV_RS13055	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ADFLV_RS13060	COG0174	glutamine synthetase
ADFLV_RS13075	COG0314	molybdopterin synthase activity
ADFLV_RS13085	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ADFLV_RS13090	COG1968	undecaprenyl-diphosphatase activity
ADFLV_RS13100	COG0772	Belongs to the SEDS family
ADFLV_RS13110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADFLV_RS13150	COG0512	Glutamine amidotransferase of anthranilate synthase
ADFLV_RS13155	COG1840	ABC-type Fe3 transport system, periplasmic component
ADFLV_RS13160	COG1178	ABC-type Fe3 transport system permease component
ADFLV_RS13165	COG3842	ATPase activity
ADFLV_RS13205	COG2183	response to ionizing radiation
ADFLV_RS13220	COG0251	oxidation-reduction process
ADFLV_RS13235	COG2095	MarC family integral membrane protein
ADFLV_RS13240	COG0765	amino acid transport
ADFLV_RS13265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADFLV_RS13285	COG0335	large ribosomal subunit rRNA binding
ADFLV_RS13290	COG0336	Belongs to the RNA methyltransferase TrmD family
ADFLV_RS13300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ADFLV_RS13305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADFLV_RS13310	COG0356	it plays a direct role in the translocation of protons across the membrane
ADFLV_RS13320	COG1074	ATP-dependent DNA helicase activity
ADFLV_RS13325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADFLV_RS13330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADFLV_RS13335	COG0723	plastoquinol--plastocyanin reductase activity
ADFLV_RS13340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ADFLV_RS13355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ADFLV_RS13365	COG0303	'Molybdopterin
ADFLV_RS13370	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ADFLV_RS13380	COG0602	queuosine metabolic process
ADFLV_RS13390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADFLV_RS13395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADFLV_RS13400	COG0825	malonyl-CoA metabolic process
ADFLV_RS13405	COG0537	adenosine 5'-monophosphoramidase activity
ADFLV_RS13410	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ADFLV_RS13415	COG0072	phenylalanine-tRNA ligase activity
ADFLV_RS13415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADFLV_RS13420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ADFLV_RS13425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ADFLV_RS13430	COG1185	polyribonucleotide nucleotidyltransferase activity
ADFLV_RS13430	COG0539	negative regulation of cytoplasmic translation
ADFLV_RS13435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADFLV_RS13440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADFLV_RS13445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADFLV_RS13445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADFLV_RS13450	COG0779	Required for maturation of 30S ribosomal subunits
ADFLV_RS13455	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ADFLV_RS13460	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADFLV_RS13470	COG0083	homoserine kinase activity
ADFLV_RS13480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ADFLV_RS13495	COG0157	Belongs to the NadC ModD family
ADFLV_RS13505	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ADFLV_RS13515	COG4773	Receptor
ADFLV_RS13525	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADFLV_RS13545	COG1538	Outer membrane efflux protein
ADFLV_RS13550	COG1846	Transcriptional regulator
ADFLV_RS13590	COG3278	Belongs to the heme-copper respiratory oxidase family
ADFLV_RS13595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ADFLV_RS13600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ADFLV_RS13605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADFLV_RS13610	COG0210	DNA helicase
ADFLV_RS13620	COG1242	4 iron, 4 sulfur cluster binding
ADFLV_RS13625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ADFLV_RS13630	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ADFLV_RS13635	COG0492	ferredoxin-NADP+ reductase activity
ADFLV_RS13640	COG3118	belongs to the thioredoxin family
ADFLV_RS13645	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADFLV_RS13675	COG0791	NLP P60 protein
ADFLV_RS13680	COG0791	NLP P60 protein
ADFLV_RS13695	COG0697	spore germination
ADFLV_RS13705	COG0424	maF-like protein
ADFLV_RS13715	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ADFLV_RS13720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADFLV_RS13725	COG1605	Chorismate mutase
ADFLV_RS13725	COG0077	Prephenate dehydratase
ADFLV_RS13730	COG0019	diaminopimelate decarboxylase activity
ADFLV_RS13735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADFLV_RS13740	COG0149	triose-phosphate isomerase activity
ADFLV_RS13745	COG0126	phosphoglycerate kinase activity
ADFLV_RS13755	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADFLV_RS13765	COG0018	arginyl-trna synthetase
ADFLV_RS13775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADFLV_RS13780	COG0204	Acyl-transferase
ADFLV_RS13790	COG0047	phosphoribosylformylglycinamidine synthase activity
ADFLV_RS13795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADFLV_RS13800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ADFLV_RS13805	COG0793	Belongs to the peptidase S41A family
ADFLV_RS13820	COG0585	pseudouridine synthase activity
ADFLV_RS13850	COG4191	Histidine kinase
ADFLV_RS13900	COG4974	Belongs to the 'phage' integrase family
ADFLV_RS13915	COG0129	dihydroxy-acid dehydratase activity
ADFLV_RS13920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADFLV_RS13925	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS13930	COG0642	Histidine kinase
ADFLV_RS13945	COG0702	epimerase
ADFLV_RS13950	COG1492	cobalamin metabolic process
ADFLV_RS13970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADFLV_RS13975	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ADFLV_RS13985	COG2095	MarC family integral membrane protein
ADFLV_RS13990	COG1083	cytidylyl-transferase
ADFLV_RS13990	COG2755	lipolytic protein G-D-S-L family
ADFLV_RS13995	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ADFLV_RS14010	COG4232	protein-disulfide reductase activity
ADFLV_RS14015	COG3118	belongs to the thioredoxin family
ADFLV_RS14025	COG0189	ligase activity
ADFLV_RS14040	COG3287	FIST C domain
ADFLV_RS14040	COG2199	diguanylate cyclase activity
ADFLV_RS14040	COG2200	EAL domain
ADFLV_RS14045	COG0688	phosphatidylethanolamine metabolic process
ADFLV_RS14055	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ADFLV_RS14065	COG0443	Heat shock 70 kDa protein
ADFLV_RS14070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ADFLV_RS14075	COG1420	regulation of RNA biosynthetic process
ADFLV_RS14080	COG2358	TRAP transporter, solute receptor (TAXI family
ADFLV_RS14090	COG2197	response regulator
ADFLV_RS14100	COG0101	tRNA pseudouridine synthase activity
ADFLV_RS14110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ADFLV_RS14115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADFLV_RS14120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADFLV_RS14125	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADFLV_RS14140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADFLV_RS14160	COG3980	spore coat polysaccharide biosynthesis protein
ADFLV_RS14165	COG2089	acid synthase
ADFLV_RS14170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADFLV_RS14180	COG1028	Short-chain dehydrogenase reductase Sdr
ADFLV_RS14220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADFLV_RS14255	COG1083	cytidylyl-transferase
ADFLV_RS14265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADFLV_RS14270	COG1086	Polysaccharide biosynthesis protein
ADFLV_RS14280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ADFLV_RS14285	COG0148	phosphopyruvate hydratase activity
ADFLV_RS14300	COG0475	glutathione-regulated potassium exporter activity
ADFLV_RS14300	COG0569	domain protein
ADFLV_RS14305	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADFLV_RS14325	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ADFLV_RS14335	COG1007	ATP synthesis coupled electron transport
ADFLV_RS14345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADFLV_RS14350	COG0713	ATP synthesis coupled electron transport
ADFLV_RS14355	COG0839	Belongs to the complex I subunit 6 family
ADFLV_RS14360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_RS14365	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADFLV_RS14370	COG1034	ATP synthesis coupled electron transport
ADFLV_RS14385	COG0649	NAD binding
ADFLV_RS14395	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_RS14400	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_RS14405	COG1222	aaa ATPase
ADFLV_RS14435	COG0659	secondary active sulfate transmembrane transporter activity
ADFLV_RS14445	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ADFLV_RS14450	COG1252	NADH dehydrogenase
ADFLV_RS14455	COG0733	neurotransmitter:sodium symporter activity
ADFLV_RS14465	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADFLV_RS14475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ADFLV_RS14480	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADFLV_RS14485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADFLV_RS14505	COG0445	tRNA wobble uridine modification
ADFLV_RS14520	COG0348	domain, Protein
ADFLV_RS14525	COG0504	CTP synthase activity
ADFLV_RS14530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ADFLV_RS14530	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ADFLV_RS14545	COG0693	protein deglycase activity
ADFLV_RS14560	COG0587	DNA-directed DNA polymerase activity
ADFLV_RS14565	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ADFLV_RS14580	COG0315	cyclic pyranopterin monophosphate synthase activity
ADFLV_RS14585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ADFLV_RS14615	COG0670	Belongs to the BI1 family
ADFLV_RS14620	COG0352	thiamine-phosphate diphosphorylase activity
ADFLV_RS14630	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADFLV_RS14640	COG0233	cytoplasmic translational termination
ADFLV_RS14645	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ADFLV_RS14655	COG2814	Major facilitator Superfamily
ADFLV_RS14660	COG1196	nuclear chromosome segregation
ADFLV_RS14660	COG3264	Mechanosensitive ion channel
ADFLV_RS14670	COG3022	response to hydroperoxide
ADFLV_RS14675	COG3012	SEC-C Motif Domain Protein
ADFLV_RS14695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADFLV_RS14705	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ADFLV_RS14720	COG1704	LemA family
ADFLV_RS14735	COG0546	phosphoglycolate phosphatase activity
ADFLV_RS14755	COG2814	Major facilitator Superfamily
ADFLV_RS14765	COG4191	Histidine kinase
ADFLV_RS14770	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS14790	COG3706	GGDEF domain
ADFLV_RS14800	COG0840	transmembrane signaling receptor activity
ADFLV_RS14805	COG3437	response regulator, receiver
ADFLV_RS14805	COG0784	Response regulator, receiver
ADFLV_RS14830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADFLV_RS14855	COG2081	HI0933 family
ADFLV_RS14885	COG1959	2 iron, 2 sulfur cluster binding
ADFLV_RS14900	COG0175	sulfate reduction
ADFLV_RS14905	COG0175	sulfate reduction
ADFLV_RS14910	COG2895	sulfate adenylyltransferase (ATP) activity
ADFLV_RS14920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADFLV_RS14925	COG1408	metallophosphoesterase
ADFLV_RS14930	COG0071	Belongs to the small heat shock protein (HSP20) family
ADFLV_RS14950	COG0840	transmembrane signaling receptor activity
ADFLV_RS14960	COG4208	sulfate ABC transporter
ADFLV_RS14965	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ADFLV_RS14970	COG3287	FIST C domain
ADFLV_RS14970	COG2199	diguanylate cyclase activity
ADFLV_RS14970	COG2200	EAL domain
ADFLV_RS14975	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ADFLV_RS14980	COG1959	2 iron, 2 sulfur cluster binding
ADFLV_RS15000	COG2308	Evidence 4 Homologs of previously reported genes of
ADFLV_RS15020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ADFLV_RS15025	COG1858	cytochrome C peroxidase
ADFLV_RS15050	COG0745	RESPONSE REGULATOR receiver
ADFLV_RS15055	COG0642	Histidine kinase
ADFLV_RS15060	COG2226	methyltransferase
ADFLV_RS15070	COG3437	response regulator, receiver
ADFLV_RS15070	COG0784	Response regulator, receiver
ADFLV_RS15075	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ADFLV_RS15080	COG2066	Belongs to the glutaminase family
ADFLV_RS15085	COG2860	membrane
ADFLV_RS15095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADFLV_RS15100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group