locus-tag	class	description
AELL_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AELL_RS00010	COG0592	DNA-directed DNA polymerase activity
AELL_RS00015	COG0187	DNA topoisomerase II activity
AELL_RS00020	COG0492	ferredoxin-NADP+ reductase activity
AELL_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AELL_RS00035	COG1238	metal cluster binding
AELL_RS00045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AELL_RS00070	COG1053	succinate dehydrogenase
AELL_RS00075	COG0667	Aldo Keto reductase
AELL_RS00085	COG3842	ATPase activity
AELL_RS00110	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AELL_RS00115	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AELL_RS00125	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AELL_RS00135	COG5002	protein histidine kinase activity
AELL_RS00140	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AELL_RS00145	COG0633	Ferredoxin
AELL_RS00165	COG0716	FMN binding
AELL_RS00200	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AELL_RS00205	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AELL_RS00210	COG2249	NAD(P)H dehydrogenase (quinone) activity
AELL_RS00215	COG1733	regulation of RNA biosynthetic process
AELL_RS00235	COG0426	domain, Protein
AELL_RS00260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AELL_RS00290	COG0840	transmembrane signaling receptor activity
AELL_RS00295	COG0840	transmembrane signaling receptor activity
AELL_RS00300	COG0564	pseudouridine synthase activity
AELL_RS00305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AELL_RS00310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AELL_RS00315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AELL_RS00335	COG2954	triphosphatase activity
AELL_RS00340	COG1151	hydroxylamine reductase activity
AELL_RS00350	COG0493	'glutamate synthase
AELL_RS00355	COG2885	chlorophyll binding
AELL_RS00360	COG0052	Belongs to the universal ribosomal protein uS2 family
AELL_RS00365	COG0604	alcohol dehydrogenase
AELL_RS00370	COG1733	regulation of RNA biosynthetic process
AELL_RS00380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AELL_RS00385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AELL_RS00410	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AELL_RS00415	COG0745	RESPONSE REGULATOR receiver
AELL_RS00420	COG4191	Histidine kinase
AELL_RS00425	COG1556	Lactate utilization protein
AELL_RS00430	COG1139	Iron-sulfur cluster binding protein
AELL_RS00435	COG0247	lactate metabolic process
AELL_RS00445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AELL_RS00445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AELL_RS00450	COG0511	ligase activity, forming carbon-carbon bonds
AELL_RS00455	COG0439	Biotin carboxylase
AELL_RS00460	COG0513	Belongs to the DEAD box helicase family
AELL_RS00465	COG0306	phosphate transporter
AELL_RS00475	COG0367	asparagine synthase
AELL_RS00485	COG0778	Nitroreductase
AELL_RS00490	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AELL_RS00500	COG1053	succinate dehydrogenase
AELL_RS00510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AELL_RS00515	COG1981	membrane
AELL_RS00520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AELL_RS00520	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AELL_RS00525	COG1187	pseudouridine synthase activity
AELL_RS00530	COG0517	IMP dehydrogenase activity
AELL_RS00530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AELL_RS00535	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AELL_RS00540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AELL_RS00545	COG0107	imidazoleglycerol-phosphate synthase activity
AELL_RS00560	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AELL_RS00565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AELL_RS00570	COG0724	RNA recognition motif
AELL_RS00575	COG0745	RESPONSE REGULATOR receiver
AELL_RS00580	COG0642	Histidine kinase
AELL_RS00615	COG0534	Mate efflux family protein
AELL_RS00620	COG0460	homoserine dehydrogenase
AELL_RS00625	COG0436	Aminotransferase
AELL_RS00640	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AELL_RS00645	COG0254	rRNA binding
AELL_RS00650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AELL_RS00680	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AELL_RS00755	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AELL_RS00765	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AELL_RS00770	COG0237	dephospho-CoA kinase activity
AELL_RS00775	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AELL_RS00780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AELL_RS00785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AELL_RS00800	COG2353	YceI-like domain
AELL_RS00805	COG1846	Transcriptional regulator
AELL_RS00810	COG1280	lysine exporter protein (LysE YggA)
AELL_RS00815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AELL_RS00820	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AELL_RS00825	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AELL_RS00835	COG0505	Belongs to the CarA family
AELL_RS00840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AELL_RS00850	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AELL_RS00850	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AELL_RS00865	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AELL_RS00870	COG0489	protein tyrosine kinase activity
AELL_RS00880	COG0140	phosphoribosyl-ATP diphosphatase activity
AELL_RS00880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AELL_RS00905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AELL_RS00915	COG1410	methionine synthase
AELL_RS00915	COG0646	methionine synthase
AELL_RS00920	COG0697	spore germination
AELL_RS00930	COG1979	alcohol dehydrogenase
AELL_RS00935	COG3647	Membrane
AELL_RS00950	COG1686	Belongs to the peptidase S11 family
AELL_RS00965	COG1854	S-ribosylhomocysteine lyase activity
AELL_RS00975	COG1335	isochorismatase
AELL_RS01010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AELL_RS01035	COG1013	pyruvate-flavodoxin oxidoreductase activity
AELL_RS01040	COG0674	pyruvate-flavodoxin oxidoreductase activity
AELL_RS01050	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AELL_RS01055	COG0546	phosphoglycolate phosphatase activity
AELL_RS01065	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AELL_RS01070	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AELL_RS01075	COG2205	protein histidine kinase activity
AELL_RS01090	COG0704	Plays a role in the regulation of phosphate uptake
AELL_RS01095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AELL_RS01100	COG0581	inorganic phosphate transmembrane transporter activity
AELL_RS01105	COG0573	inorganic phosphate transmembrane transporter activity
AELL_RS01110	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AELL_RS01115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AELL_RS01125	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AELL_RS01130	COG0268	Binds directly to 16S ribosomal RNA
AELL_RS01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AELL_RS01140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AELL_RS01145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AELL_RS01150	COG0746	molybdenum cofactor guanylyltransferase activity
AELL_RS01155	COG0446	pyridine nucleotide-disulphide oxidoreductase
AELL_RS01170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AELL_RS01175	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AELL_RS01180	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AELL_RS01185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AELL_RS01215	COG0575	Belongs to the CDS family
AELL_RS01220	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AELL_RS01240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AELL_RS01245	COG0023	Translation Initiation Factor
AELL_RS01250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AELL_RS01250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AELL_RS01255	COG1324	tolerance protein
AELL_RS01260	COG2022	thiamine diphosphate biosynthetic process
AELL_RS01315	COG0840	transmembrane signaling receptor activity
AELL_RS01335	COG0840	transmembrane signaling receptor activity
AELL_RS01345	COG0840	transmembrane signaling receptor activity
AELL_RS01355	COG2198	Histidine kinase
AELL_RS01355	COG0643	Histidine kinase
AELL_RS01360	COG0840	transmembrane signaling receptor activity
AELL_RS01370	COG2203	Gaf domain
AELL_RS01370	COG3706	GGDEF domain
AELL_RS01370	COG4251	negative regulation of phosphorylation
AELL_RS01370	COG5001	Diguanylate cyclase
AELL_RS01380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AELL_RS01495	COG0582	viral genome integration into host DNA
AELL_RS01525	COG3630	sodium ion export across plasma membrane
AELL_RS01580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AELL_RS01590	COG4191	Histidine kinase
AELL_RS01595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AELL_RS01610	COG5001	Diguanylate cyclase
AELL_RS01610	COG4251	negative regulation of phosphorylation
AELL_RS01610	COG3706	GGDEF domain
AELL_RS01610	COG2203	Gaf domain
AELL_RS01620	COG1346	cytolysis
AELL_RS01625	COG0640	Transcriptional regulator
AELL_RS01635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AELL_RS01645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AELL_RS01650	COG2059	Chromate
AELL_RS01675	COG0659	secondary active sulfate transmembrane transporter activity
AELL_RS01695	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AELL_RS01720	COG0004	ammonium transporteR
AELL_RS01730	COG0004	ammonium transporteR
AELL_RS01735	COG0347	Belongs to the P(II) protein family
AELL_RS01740	COG0418	dihydroorotase activity
AELL_RS01750	COG1706	bacterial-type flagellum-dependent cell motility
AELL_RS01790	COG4786	Flagellar basal body rod
AELL_RS01790	COG1256	bacterial-type flagellum assembly
AELL_RS01795	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AELL_RS01815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AELL_RS01820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AELL_RS01825	COG0601	transmembrane transport
AELL_RS01830	COG0736	holo-[acyl-carrier-protein] synthase activity
AELL_RS01845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AELL_RS01855	COG0560	Phosphoserine phosphatase
AELL_RS01860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AELL_RS01865	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AELL_RS01870	COG3248	Nucleoside-binding outer membrane protein
AELL_RS01875	COG1393	Belongs to the ArsC family
AELL_RS01880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AELL_RS01885	COG0343	queuine tRNA-ribosyltransferase activity
AELL_RS01895	COG0436	Aminotransferase
AELL_RS01910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AELL_RS01920	COG2861	carbohydrate metabolic process
AELL_RS01925	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AELL_RS01930	COG0557	exoribonuclease II activity
AELL_RS01945	COG0360	Binds together with S18 to 16S ribosomal RNA
AELL_RS01950	COG0629	single-stranded DNA binding
AELL_RS01955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AELL_RS01965	COG0215	cysteine-tRNA ligase activity
AELL_RS01970	COG0195	Participates in both transcription termination and antitermination
AELL_RS01980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AELL_RS01985	COG2121	Domain of unknown function (DUF374)
AELL_RS01995	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AELL_RS02005	COG0288	reversible hydration of carbon dioxide
AELL_RS02010	COG0156	8-amino-7-oxononanoate synthase activity
AELL_RS02015	COG0792	nuclease activity
AELL_RS02035	COG0469	pyruvate kinase activity
AELL_RS02045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AELL_RS02055	COG0540	Belongs to the ATCase OTCase family
AELL_RS02060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AELL_RS02065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AELL_RS02080	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AELL_RS02085	COG1687	branched-chain amino acid
AELL_RS02090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AELL_RS02095	COG0416	fatty acid biosynthetic process
AELL_RS02100	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AELL_RS02110	COG0105	UTP biosynthetic process
AELL_RS02120	COG0450	alkyl hydroperoxide reductase
AELL_RS02125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AELL_RS02135	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AELL_RS02140	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AELL_RS02145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AELL_RS02155	COG0181	hydroxymethylbilane synthase activity
AELL_RS02170	COG2828	Protein conserved in bacteria
AELL_RS02175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AELL_RS02185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AELL_RS02195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AELL_RS02220	COG0514	ATP-dependent DNA helicase (RecQ)
AELL_RS02235	COG1451	nucleotide metabolic process
AELL_RS02240	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AELL_RS02250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AELL_RS02255	COG1053	succinate dehydrogenase
AELL_RS02265	COG1007	ATP synthesis coupled electron transport
AELL_RS02275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AELL_RS02280	COG0713	ATP synthesis coupled electron transport
AELL_RS02285	COG0839	Belongs to the complex I subunit 6 family
AELL_RS02290	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AELL_RS02295	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AELL_RS02305	COG0372	Belongs to the citrate synthase family
AELL_RS02320	COG0649	NAD binding
AELL_RS02320	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AELL_RS02325	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AELL_RS02330	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AELL_RS02335	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AELL_RS02340	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AELL_RS02345	COG3610	response to peptide
AELL_RS02350	COG2966	Psort location CytoplasmicMembrane, score
AELL_RS02360	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AELL_RS02365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AELL_RS02380	COG3706	GGDEF domain
AELL_RS02400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AELL_RS02405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AELL_RS02405	COG1333	cytochrome c biogenesis protein
AELL_RS02410	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AELL_RS02415	COG3005	denitrification pathway
AELL_RS02430	COG0840	transmembrane signaling receptor activity
AELL_RS02450	COG3043	anaerobic respiration
AELL_RS02455	COG0348	domain, Protein
AELL_RS02460	COG0437	4 iron, 4 sulfur cluster binding
AELL_RS02465	COG0243	molybdopterin cofactor binding
AELL_RS02470	COG3287	FIST C domain
AELL_RS02470	COG2200	EAL domain
AELL_RS02470	COG2199	diguanylate cyclase activity
AELL_RS02475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AELL_RS02475	COG1648	precorrin-2 dehydrogenase activity
AELL_RS02490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AELL_RS02495	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AELL_RS02510	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AELL_RS02515	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AELL_RS02520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AELL_RS02530	COG2404	hydrolase activity, acting on ester bonds
AELL_RS02535	COG1832	CoA-binding protein
AELL_RS02540	COG0642	Histidine kinase
AELL_RS02545	COG0745	RESPONSE REGULATOR receiver
AELL_RS02550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AELL_RS02555	COG0191	fructose-bisphosphate aldolase activity
AELL_RS02565	COG2205	protein histidine kinase activity
AELL_RS02565	COG2198	Histidine kinase
AELL_RS02565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AELL_RS02565	COG0784	Response regulator, receiver
AELL_RS02590	COG0811	peptide transport
AELL_RS02600	COG4191	Histidine kinase
AELL_RS02610	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AELL_RS02615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AELL_RS02625	COG0142	geranyltranstransferase activity
AELL_RS02630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AELL_RS02635	COG0442	prolyl-tRNA aminoacylation
AELL_RS02640	COG0668	transmembrane transport
AELL_RS02660	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AELL_RS02665	COG1862	Preprotein translocase
AELL_RS02670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AELL_RS02675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AELL_RS02680	COG0840	transmembrane signaling receptor activity
AELL_RS02695	COG0495	leucyl-tRNA aminoacylation
AELL_RS02705	COG0285	dihydrofolate synthase activity
AELL_RS02745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AELL_RS02765	COG5001	Diguanylate cyclase
AELL_RS02765	COG3706	GGDEF domain
AELL_RS02765	COG4251	negative regulation of phosphorylation
AELL_RS02765	COG2203	Gaf domain
AELL_RS02775	COG0745	RESPONSE REGULATOR receiver
AELL_RS02780	COG0642	Histidine kinase
AELL_RS02785	COG2081	HI0933 family
AELL_RS02790	COG0840	transmembrane signaling receptor activity
AELL_RS02800	COG0840	transmembrane signaling receptor activity
AELL_RS02810	COG1692	metallophosphoesterase
AELL_RS02825	COG2226	methyltransferase
AELL_RS02830	COG1570	exodeoxyribonuclease VII activity
AELL_RS02845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AELL_RS02855	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AELL_RS02860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AELL_RS02870	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AELL_RS02875	COG0459	protein refolding
AELL_RS02940	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AELL_RS02955	COG1408	metallophosphoesterase
AELL_RS02965	COG2353	YceI-like domain
AELL_RS02980	COG0577	efflux transmembrane transporter activity
AELL_RS02980	COG1136	(ABC) transporter
AELL_RS02995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AELL_RS03010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AELL_RS03015	COG0352	thiamine-phosphate diphosphorylase activity
AELL_RS03020	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AELL_RS03030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AELL_RS03035	COG2264	protein methyltransferase activity
AELL_RS03040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AELL_RS03045	COG3437	response regulator, receiver
AELL_RS03045	COG0784	Response regulator, receiver
AELL_RS03055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AELL_RS03075	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AELL_RS03110	COG1132	(ABC) transporter
AELL_RS03125	COG3706	GGDEF domain
AELL_RS03130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AELL_RS03135	COG1090	epimerase
AELL_RS03140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AELL_RS03150	COG0481	GTPase activity
AELL_RS03165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AELL_RS03180	COG0482	sulfurtransferase activity
AELL_RS03185	COG0482	sulfurtransferase activity
AELL_RS03190	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AELL_RS03195	COG0006	proline dipeptidase activity
AELL_RS03200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AELL_RS03205	COG0402	S-adenosylhomocysteine deaminase activity
AELL_RS03210	COG0616	signal peptide processing
AELL_RS03220	COG0280	phosphate acetyltransferase
AELL_RS03225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AELL_RS03230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AELL_RS03235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AELL_RS03240	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AELL_RS03240	COG0517	IMP dehydrogenase activity
AELL_RS03245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AELL_RS03255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AELL_RS03265	COG2176	DNA-directed DNA polymerase activity
AELL_RS03285	COG0745	RESPONSE REGULATOR receiver
AELL_RS03335	COG1058	Belongs to the CinA family
AELL_RS03335	COG1546	Belongs to the CinA family
AELL_RS03340	COG0579	oxidoreductase
AELL_RS03345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AELL_RS03360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AELL_RS03390	COG0714	Associated with various cellular activities
AELL_RS03395	COG0052	Belongs to the universal ribosomal protein uS2 family
AELL_RS03400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AELL_RS03405	COG1136	(ABC) transporter
AELL_RS03415	COG0194	GDP metabolic process
AELL_RS03420	COG5002	protein histidine kinase activity
AELL_RS03420	COG5001	Diguanylate cyclase
AELL_RS03425	COG2217	Heavy metal translocating P-type atpase
AELL_RS03440	COG4608	Belongs to the ABC transporter superfamily
AELL_RS03445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AELL_RS03460	COG1355	regulation of microtubule-based process
AELL_RS03470	COG1121	(ABC) transporter
AELL_RS03475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AELL_RS03485	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AELL_RS03500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AELL_RS03510	COG0210	DNA helicase
AELL_RS03515	COG0569	domain protein
AELL_RS03515	COG0475	glutathione-regulated potassium exporter activity
AELL_RS03520	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AELL_RS03545	COG3258	Cytochrome c
AELL_RS03560	COG1331	Highly conserved protein containing a thioredoxin domain
AELL_RS03575	COG0492	ferredoxin-NADP+ reductase activity
AELL_RS03620	COG0525	valine-tRNA ligase activity
AELL_RS03645	COG0454	-acetyltransferase
AELL_RS03655	COG4895	conserved protein (DUF2196)
AELL_RS03660	COG1047	Peptidyl-prolyl cis-trans
AELL_RS03670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AELL_RS03675	COG2200	EAL domain
AELL_RS03685	COG2814	Major facilitator Superfamily
AELL_RS03690	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AELL_RS03710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AELL_RS03715	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AELL_RS03720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AELL_RS03740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AELL_RS03745	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AELL_RS03755	COG2200	EAL domain
AELL_RS03755	COG3287	FIST C domain
AELL_RS03755	COG2199	diguanylate cyclase activity
AELL_RS03765	COG0439	Biotin carboxylase
AELL_RS03790	COG3046	protein related to deoxyribodipyrimidine photolyase
AELL_RS03795	COG3287	FIST C domain
AELL_RS03795	COG2200	EAL domain
AELL_RS03795	COG2199	diguanylate cyclase activity
AELL_RS03805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AELL_RS03820	COG3040	lipid binding
AELL_RS03830	COG4221	oxidoreductase activity
AELL_RS03840	COG2166	iron-sulfur cluster assembly
AELL_RS03845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AELL_RS03855	COG0396	ATPase activity
AELL_RS03860	COG0719	Fe-S assembly protein
AELL_RS03870	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AELL_RS03870	COG2906	2 iron, 2 sulfur cluster binding
AELL_RS03870	COG0822	iron-sulfur transferase activity
AELL_RS03980	COG2239	Acts as a magnesium transporter
AELL_RS04010	COG0165	Argininosuccinate lyase
AELL_RS04015	COG0835	chemotaxis
AELL_RS04015	COG0784	Response regulator, receiver
AELL_RS04020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AELL_RS04025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AELL_RS04040	COG0556	nucleotide-excision repair
AELL_RS04045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AELL_RS04060	COG4771	TonB-dependent receptor
AELL_RS04070	COG0698	ribose 5-phosphate isomerase
AELL_RS04075	COG0681	Belongs to the peptidase S26 family
AELL_RS04080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AELL_RS04085	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AELL_RS04090	COG0193	aminoacyl-tRNA hydrolase activity
AELL_RS04105	COG0860	N-Acetylmuramoyl-L-alanine amidase
AELL_RS04115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AELL_RS04125	COG1758	RNA polymerase activity
AELL_RS04130	COG0528	UMP kinase activity
AELL_RS04140	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AELL_RS04145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AELL_RS04150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AELL_RS04160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AELL_RS04165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AELL_RS04180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AELL_RS04185	COG0305	Participates in initiation and elongation during chromosome replication
AELL_RS04190	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AELL_RS04200	COG1793	dna ligase
AELL_RS04205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AELL_RS04210	COG0133	tryptophan synthase activity
AELL_RS04220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AELL_RS04230	COG0848	biopolymer transport protein
AELL_RS04250	COG0577	efflux transmembrane transporter activity
AELL_RS04250	COG1136	(ABC) transporter
AELL_RS04255	COG0577	efflux transmembrane transporter activity
AELL_RS04255	COG1136	(ABC) transporter
AELL_RS04300	COG0735	belongs to the Fur family
AELL_RS04315	COG3852	Histidine kinase
AELL_RS04320	COG0745	RESPONSE REGULATOR receiver
AELL_RS04325	COG4773	Receptor
AELL_RS04350	COG4774	siderophore transport
AELL_RS04355	COG3128	pkhd-type hydroxylase
AELL_RS04370	COG0784	Response regulator, receiver
AELL_RS04375	COG4771	TonB-dependent receptor
AELL_RS04390	COG0012	GTP binding
AELL_RS04410	COG3123	guanosine phosphorylase activity
AELL_RS04430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AELL_RS04435	COG0585	pseudouridine synthase activity
AELL_RS04445	COG0840	transmembrane signaling receptor activity
AELL_RS04450	COG0632	four-way junction helicase activity
AELL_RS04455	COG1181	Belongs to the D-alanine--D-alanine ligase family
AELL_RS04460	COG0596	Alpha beta hydrolase
AELL_RS04465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AELL_RS04480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AELL_RS04485	COG0051	transcription antitermination factor activity, RNA binding
AELL_RS04490	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AELL_RS04495	COG0088	Forms part of the polypeptide exit tunnel
AELL_RS04500	COG0089	rRNA binding
AELL_RS04505	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AELL_RS04510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AELL_RS04515	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AELL_RS04520	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AELL_RS04525	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AELL_RS04530	COG0255	Belongs to the universal ribosomal protein uL29 family
AELL_RS04535	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AELL_RS04540	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AELL_RS04545	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AELL_RS04550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AELL_RS04555	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AELL_RS04560	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AELL_RS04565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AELL_RS04570	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AELL_RS04575	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AELL_RS04580	COG0200	Binds to the 23S rRNA
AELL_RS04585	COG0201	protein transport
AELL_RS04590	COG0024	Methionine aminopeptidase
AELL_RS04595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AELL_RS04605	COG1573	uracil-dna glycosylase
AELL_RS04615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AELL_RS04630	COG1032	radical SAM domain protein
AELL_RS04640	COG0563	adenylate kinase activity
AELL_RS04655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AELL_RS04660	COG0322	excinuclease ABC activity
AELL_RS04670	COG3706	GGDEF domain
AELL_RS04675	COG4565	transcriptional regulatory protein
AELL_RS04685	COG3201	nicotinamide mononucleotide transporter
AELL_RS04690	COG0386	Belongs to the glutathione peroxidase family
AELL_RS04695	COG0840	transmembrane signaling receptor activity
AELL_RS04705	COG0745	RESPONSE REGULATOR receiver
AELL_RS04715	COG0784	Response regulator, receiver
AELL_RS04715	COG2205	protein histidine kinase activity
AELL_RS04765	COG0829	nickel cation binding
AELL_RS04770	COG0831	urea catabolic process
AELL_RS04770	COG0832	Belongs to the urease beta subunit family
AELL_RS04775	COG0804	urea catabolic process
AELL_RS04780	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AELL_RS04790	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AELL_RS04820	COG3706	GGDEF domain
AELL_RS04825	COG0708	Exodeoxyribonuclease III
AELL_RS04855	COG0166	Belongs to the GPI family
AELL_RS04900	COG2252	PERMEase
AELL_RS04905	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AELL_RS04915	COG2363	Small membrane protein
AELL_RS04925	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AELL_RS04930	COG2233	PERMEase
AELL_RS04935	COG1666	GTP binding
AELL_RS04945	COG0745	RESPONSE REGULATOR receiver
AELL_RS04950	COG0642	Histidine kinase
AELL_RS04970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AELL_RS04975	COG0135	phosphoribosylanthranilate isomerase activity
AELL_RS04980	COG2176	DNA-directed DNA polymerase activity
AELL_RS04985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AELL_RS04995	COG1013	pyruvate-flavodoxin oxidoreductase activity
AELL_RS05000	COG0674	pyruvate-flavodoxin oxidoreductase activity
AELL_RS05000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AELL_RS05010	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AELL_RS05015	COG0727	PFAM Uncharacterised protein family (UPF0153)
AELL_RS05025	COG0134	indole-3-glycerol-phosphate synthase activity
AELL_RS05035	COG1942	4-Oxalocrotonate Tautomerase
AELL_RS05040	COG0840	transmembrane signaling receptor activity
AELL_RS05045	COG0840	transmembrane signaling receptor activity
AELL_RS05050	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AELL_RS05055	COG0750	zinc metalloprotease
AELL_RS05060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AELL_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
AELL_RS05070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AELL_RS05085	COG0167	dihydroorotate dehydrogenase activity
AELL_RS05090	COG1132	(ABC) transporter
AELL_RS05095	COG0728	peptidoglycan biosynthetic process
AELL_RS05105	COG1592	Rubrerythrin
AELL_RS05115	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AELL_RS05120	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AELL_RS05155	COG1858	cytochrome C peroxidase
AELL_RS05170	COG0552	protein localization to endoplasmic reticulum
AELL_RS05175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AELL_RS05185	COG1418	mRNA catabolic process
AELL_RS05190	COG0742	ribosomal rna small subunit methyltransferase
AELL_RS05195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AELL_RS05205	COG0300	oxidoreductase activity
AELL_RS05220	COG3258	Cytochrome c
AELL_RS05235	COG5002	protein histidine kinase activity
AELL_RS05250	COG1610	YqeY-like protein
AELL_RS05255	COG0488	(ABC) transporter
AELL_RS05265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AELL_RS05275	COG1451	nucleotide metabolic process
AELL_RS05285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AELL_RS05290	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AELL_RS05295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AELL_RS05295	COG0519	Catalyzes the synthesis of GMP from XMP
AELL_RS05340	COG0596	Alpha beta hydrolase
AELL_RS05345	COG0204	Acyl-transferase
AELL_RS05365	COG0564	pseudouridine synthase activity
AELL_RS05395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AELL_RS05405	COG2223	nitrite transmembrane transporter activity
AELL_RS05410	COG1028	Short-chain dehydrogenase reductase Sdr
AELL_RS05415	COG0519	Catalyzes the synthesis of GMP from XMP
AELL_RS05415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AELL_RS05445	COG1253	flavin adenine dinucleotide binding
AELL_RS05450	COG2989	Protein conserved in bacteria
AELL_RS05460	COG0628	permease
AELL_RS05465	COG0748	coenzyme F420 binding
AELL_RS05475	COG4536	flavin adenine dinucleotide binding
AELL_RS05490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AELL_RS05495	COG1716	ATPase activity
AELL_RS05495	COG5001	Diguanylate cyclase
AELL_RS05500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AELL_RS05515	COG0513	Belongs to the DEAD box helicase family
AELL_RS05525	COG1045	serine acetyltransferase
AELL_RS05530	COG1166	arginine decarboxylase activity
AELL_RS05535	COG0124	histidyl-tRNA synthetase
AELL_RS05540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AELL_RS05545	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AELL_RS05550	COG0163	prenyltransferase activity
AELL_RS05560	COG0359	binds to the 23S rRNA
AELL_RS05565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AELL_RS05570	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AELL_RS05580	COG0084	hydrolase, TatD family'
AELL_RS05590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AELL_RS05595	COG0131	Imidazoleglycerol-phosphate dehydratase
AELL_RS05600	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AELL_RS05615	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AELL_RS05620	COG0456	acetyltransferase
AELL_RS05625	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AELL_RS05630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AELL_RS05650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AELL_RS05660	COG2897	thiosulfate sulfurtransferase activity
AELL_RS05665	COG3852	Histidine kinase
AELL_RS05670	COG1338	Plays a role in the flagellum-specific transport system
AELL_RS05675	COG0768	penicillin binding
AELL_RS05730	COG0849	cell division
AELL_RS05735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AELL_RS05740	COG2391	methyltransferase activity
AELL_RS05765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AELL_RS05785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AELL_RS05795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AELL_RS05855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AELL_RS05860	COG1360	Flagellar Motor Protein
AELL_RS05865	COG0861	Integral membrane protein TerC family
AELL_RS05870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AELL_RS05875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AELL_RS05890	COG0842	Transport permease protein
AELL_RS05895	COG0842	Transport permease protein
AELL_RS05900	COG1131	(ABC) transporter
AELL_RS05905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AELL_RS05930	COG2197	response regulator
AELL_RS05935	COG0789	Transcriptional regulator
AELL_RS05940	COG0484	heat shock protein binding
AELL_RS05955	COG2201	protein-glutamate methylesterase activity
AELL_RS05965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AELL_RS05965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AELL_RS05980	COG3077	Addiction module antitoxin, RelB DinJ family
AELL_RS06070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AELL_RS06080	COG2205	protein histidine kinase activity
AELL_RS06105	COG0784	Response regulator, receiver
AELL_RS06105	COG2205	protein histidine kinase activity
AELL_RS06130	COG2132	Multicopper oxidase
AELL_RS06150	COG2217	Heavy metal translocating P-type atpase
AELL_RS06170	COG0642	Histidine kinase
AELL_RS06190	COG0745	RESPONSE REGULATOR receiver
AELL_RS06195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AELL_RS06230	COG2217	Heavy metal translocating P-type atpase
AELL_RS06235	COG1742	UPF0060 membrane protein
AELL_RS06245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AELL_RS06250	COG2337	Toxic component of a toxin-antitoxin (TA) module
AELL_RS06285	COG0582	viral genome integration into host DNA
AELL_RS06295	COG0776	regulation of translation
AELL_RS06305	COG0275	rRNA processing
AELL_RS06335	COG0318	PFAM AMP-dependent synthetase and ligase
AELL_RS06345	COG4865	methylaspartate mutase activity
AELL_RS06360	COG0039	L-malate dehydrogenase activity
AELL_RS06380	COG4591	ABC-type transport system involved in lipoprotein release permease component
AELL_RS06385	COG0653	protein targeting
AELL_RS06400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AELL_RS06410	COG1696	Membrane protein involved in D-alanine export
AELL_RS06425	COG4191	Histidine kinase
AELL_RS06425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AELL_RS06430	COG1587	Uroporphyrinogen-III synthase
AELL_RS06430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AELL_RS06440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AELL_RS06445	COG0840	transmembrane signaling receptor activity
AELL_RS06450	COG2200	EAL domain
AELL_RS06450	COG2199	diguanylate cyclase activity
AELL_RS06450	COG3287	FIST C domain
AELL_RS06455	COG0243	molybdopterin cofactor binding
AELL_RS06460	COG0437	4 iron, 4 sulfur cluster binding
AELL_RS06465	COG0243	molybdopterin cofactor binding
AELL_RS06470	COG2199	diguanylate cyclase activity
AELL_RS06470	COG3287	FIST C domain
AELL_RS06470	COG2200	EAL domain
AELL_RS06475	COG2815	serine threonine protein kinase
AELL_RS06475	COG0515	serine threonine protein kinase
AELL_RS06480	COG2223	nitrite transmembrane transporter activity
AELL_RS06485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AELL_RS06485	COG1116	anion transmembrane transporter activity
AELL_RS06495	COG1116	anion transmembrane transporter activity
AELL_RS06500	COG0754	glutathionylspermidine amidase activity
AELL_RS06510	COG2199	diguanylate cyclase activity
AELL_RS06525	COG0745	RESPONSE REGULATOR receiver
AELL_RS06535	COG0745	RESPONSE REGULATOR receiver
AELL_RS06550	COG0582	viral genome integration into host DNA
AELL_RS06560	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AELL_RS06575	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AELL_RS06635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AELL_RS06640	COG4106	trans-aconitate 2-methyltransferase activity
AELL_RS06650	COG0280	phosphate acetyltransferase
AELL_RS06650	COG0281	malic enzyme
AELL_RS06655	COG0788	formyltetrahydrofolate deformylase activity
AELL_RS06660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AELL_RS06675	COG0840	transmembrane signaling receptor activity
AELL_RS06680	COG0745	RESPONSE REGULATOR receiver
AELL_RS06690	COG0330	HflC and HflK could
AELL_RS06705	COG1294	oxidase, subunit
AELL_RS06710	COG1271	oxidase subunit
AELL_RS06720	COG1342	Belongs to the UPF0251 family
AELL_RS06750	COG0450	alkyl hydroperoxide reductase
AELL_RS06770	COG0848	biopolymer transport protein
AELL_RS06785	COG0419	ATPase involved in DNA repair
AELL_RS06820	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AELL_RS06825	COG1187	pseudouridine synthase activity
AELL_RS06850	COG4206	TonB-dependent receptor
AELL_RS06865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AELL_RS06880	COG1797	cobyrinic acid a,c-diamide synthase activity
AELL_RS06900	COG0667	Aldo Keto reductase
AELL_RS06905	COG0840	transmembrane signaling receptor activity
AELL_RS06910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AELL_RS06925	COG0824	Thioesterase
AELL_RS06935	COG0501	Belongs to the peptidase M48B family
AELL_RS06940	COG1322	Protein conserved in bacteria
AELL_RS06965	COG0037	tRNA processing
AELL_RS06990	COG3706	GGDEF domain
AELL_RS06990	COG5001	Diguanylate cyclase
AELL_RS06990	COG4251	negative regulation of phosphorylation
AELL_RS06990	COG2203	Gaf domain
AELL_RS07010	COG0028	Belongs to the TPP enzyme family
AELL_RS07015	COG0440	acetolactate synthase activity
AELL_RS07020	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AELL_RS07025	COG1196	nuclear chromosome segregation
AELL_RS07025	COG1674	ftsk spoiiie
AELL_RS07030	COG0745	RESPONSE REGULATOR receiver
AELL_RS07035	COG0642	Histidine kinase
AELL_RS07045	COG1749	Flagellar hook protein flgE
AELL_RS07065	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AELL_RS07080	COG1160	GTP binding
AELL_RS07085	COG0659	secondary active sulfate transmembrane transporter activity
AELL_RS07100	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AELL_RS07170	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AELL_RS07180	COG1185	polyribonucleotide nucleotidyltransferase activity
AELL_RS07195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AELL_RS07200	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AELL_RS07205	COG2201	protein-glutamate methylesterase activity
AELL_RS07305	COG0582	viral genome integration into host DNA
AELL_RS07325	COG0339	signal peptide processing
AELL_RS07330	COG2890	protein-(glutamine-N5) methyltransferase activity
AELL_RS07335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AELL_RS07340	COG0494	nUDIX hydrolase
AELL_RS07345	COG0527	aspartate kinase activity
AELL_RS07360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AELL_RS07365	COG0287	Prephenate dehydrogenase
AELL_RS07370	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AELL_RS07375	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AELL_RS07380	COG0612	Peptidase, M16
AELL_RS07385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AELL_RS07415	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AELL_RS07425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AELL_RS07425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AELL_RS07440	COG3630	sodium ion export across plasma membrane
AELL_RS07455	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AELL_RS07575	COG2207	Transcriptional regulator
AELL_RS07580	COG0751	glycine-tRNA ligase activity
AELL_RS07600	COG0357	Ribosomal RNA small subunit methyltransferase G
AELL_RS07605	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AELL_RS07610	COG0113	porphobilinogen synthase activity
AELL_RS07615	COG0840	transmembrane signaling receptor activity
AELL_RS07620	COG0745	RESPONSE REGULATOR receiver
AELL_RS07635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AELL_RS07635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AELL_RS07640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AELL_RS07645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AELL_RS07655	COG1663	tetraacyldisaccharide 4'-kinase activity
AELL_RS07660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AELL_RS07665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AELL_RS07685	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AELL_RS07690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AELL_RS07695	COG0805	protein transport
AELL_RS07700	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AELL_RS07735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AELL_RS07750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AELL_RS07770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AELL_RS07770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AELL_RS07775	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AELL_RS07780	COG2200	EAL domain
AELL_RS07780	COG2199	diguanylate cyclase activity
AELL_RS07780	COG3287	FIST C domain
AELL_RS07785	COG3706	GGDEF domain
AELL_RS07790	COG1137	ATPase activity
AELL_RS07795	COG0802	atpase or kinase
AELL_RS07800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AELL_RS07810	COG4771	TonB-dependent receptor
AELL_RS07815	COG3706	GGDEF domain
AELL_RS07820	COG0137	argininosuccinate synthase activity
AELL_RS07830	COG0189	ligase activity
AELL_RS07835	COG1555	photosystem II stabilization
AELL_RS07865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AELL_RS07870	COG0484	heat shock protein binding
AELL_RS07875	COG0133	tryptophan synthase activity
AELL_RS07895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AELL_RS07900	COG5001	Diguanylate cyclase
AELL_RS07905	COG3706	GGDEF domain
AELL_RS07905	COG4251	negative regulation of phosphorylation
AELL_RS07905	COG2203	Gaf domain
AELL_RS07905	COG5001	Diguanylate cyclase
AELL_RS07910	COG0500	methyltransferase
AELL_RS07915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AELL_RS07915	COG1333	cytochrome c biogenesis protein
AELL_RS07920	COG0745	RESPONSE REGULATOR receiver
AELL_RS07930	COG2195	Cleaves the N-terminal amino acid of tripeptides
AELL_RS07945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AELL_RS07950	COG0784	Response regulator, receiver
AELL_RS07950	COG2205	protein histidine kinase activity
AELL_RS07960	COG0784	Response regulator, receiver
AELL_RS07960	COG3437	response regulator, receiver
AELL_RS07965	COG1607	acyl-coa hydrolase
AELL_RS07970	COG0488	(ABC) transporter
AELL_RS07985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AELL_RS07985	COG2010	Cytochrome c
AELL_RS07990	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AELL_RS08005	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AELL_RS08010	COG2201	protein-glutamate methylesterase activity
AELL_RS08015	COG0643	Histidine kinase
AELL_RS08015	COG2198	Histidine kinase
AELL_RS08020	COG3852	Histidine kinase
AELL_RS08040	COG0778	Nitroreductase
AELL_RS08055	COG2249	NAD(P)H dehydrogenase (quinone) activity
AELL_RS08060	COG1733	regulation of RNA biosynthetic process
AELL_RS08065	COG1484	DNA-dependent DNA replication
AELL_RS08095	COG2271	Major facilitator Superfamily
AELL_RS08100	COG0583	DNA-binding transcription factor activity
AELL_RS08120	COG1280	lysine exporter protein (LysE YggA)
AELL_RS08125	COG1280	lysine exporter protein (LysE YggA)
AELL_RS08130	COG1280	lysine exporter protein (LysE YggA)
AELL_RS08175	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AELL_RS08225	COG2855	membrane
AELL_RS08230	COG0583	DNA-binding transcription factor activity
AELL_RS08235	COG1881	PFAM PEBP family protein
AELL_RS08250	COG2076	Multidrug Resistance protein
AELL_RS08275	COG2824	Alkylphosphonate utilization operon protein PhnA
AELL_RS08285	COG1119	ATPase activity
AELL_RS08305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AELL_RS08325	COG1193	negative regulation of DNA recombination
AELL_RS08340	COG0471	metal ion transport
AELL_RS08345	COG0521	Mo-molybdopterin cofactor biosynthetic process
AELL_RS08355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AELL_RS08360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AELL_RS08370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AELL_RS08375	COG0513	Belongs to the DEAD box helicase family
AELL_RS08380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AELL_RS08390	COG3279	Response regulator of the LytR AlgR family
AELL_RS08405	COG0415	Belongs to the DNA photolyase family
AELL_RS08435	COG0642	Histidine kinase
AELL_RS08440	COG0745	RESPONSE REGULATOR receiver
AELL_RS08460	COG1132	(ABC) transporter
AELL_RS08465	COG0628	permease
AELL_RS08480	COG1472	Belongs to the glycosyl hydrolase 3 family
AELL_RS08500	COG1620	l-lactate permease
AELL_RS08515	COG0484	heat shock protein binding
AELL_RS08545	COG2204	response regulator
AELL_RS08550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AELL_RS08550	COG2198	Histidine kinase
AELL_RS08550	COG2205	protein histidine kinase activity
AELL_RS08550	COG0784	Response regulator, receiver
AELL_RS08560	COG1047	Peptidyl-prolyl cis-trans
AELL_RS08565	COG0516	GMP reductase activity
AELL_RS08565	COG0517	IMP dehydrogenase activity
AELL_RS08570	COG0154	amidase activity
AELL_RS08575	COG0203	ribosomal protein L17
AELL_RS08580	COG0202	RNA polymerase activity
AELL_RS08585	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AELL_RS08590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AELL_RS08595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AELL_RS08600	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AELL_RS08615	COG0473	3-isopropylmalate dehydrogenase activity
AELL_RS08620	COG0066	3-isopropylmalate dehydratase activity
AELL_RS08625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AELL_RS08645	COG3123	guanosine phosphorylase activity
AELL_RS08650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AELL_RS08665	COG0772	Belongs to the SEDS family
AELL_RS08670	COG0564	pseudouridine synthase activity
AELL_RS08675	COG0366	Alpha amylase catalytic
AELL_RS08675	COG3103	Sh3 type 3 domain protein
AELL_RS08680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AELL_RS08685	COG2884	Cell division ATP-binding protein ftsE
AELL_RS08700	COG1671	Belongs to the UPF0178 family
AELL_RS08710	COG0488	(ABC) transporter
AELL_RS08715	COG4716	Myosin-crossreactive antigen
AELL_RS08720	COG2171	N-acyltransferase activity
AELL_RS08725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AELL_RS08760	COG0309	Hydrogenase expression formation protein (HypE)
AELL_RS08775	COG0298	carbon dioxide binding
AELL_RS08780	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AELL_RS08810	COG4804	nuclease activity
AELL_RS08820	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AELL_RS08825	COG2081	HI0933 family
AELL_RS08845	COG0439	Biotin carboxylase
AELL_RS08875	COG2354	Protein conserved in bacteria
AELL_RS08890	COG2814	Major facilitator Superfamily
AELL_RS08910	COG0301	tRNA thio-modification
AELL_RS08910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AELL_RS08935	COG3263	regulation of cellular component size
AELL_RS08945	COG0517	IMP dehydrogenase activity
AELL_RS08965	COG3383	formate dehydrogenase (NAD+) activity
AELL_RS08975	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AELL_RS08990	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AELL_RS09005	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AELL_RS09010	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AELL_RS09025	COG1309	transcriptional regulator
AELL_RS09035	COG1049	propionate catabolic process, 2-methylcitrate cycle
AELL_RS09045	COG3706	GGDEF domain
AELL_RS09045	COG2203	Gaf domain
AELL_RS09045	COG5001	Diguanylate cyclase
AELL_RS09045	COG4251	negative regulation of phosphorylation
AELL_RS09050	COG0242	peptide deformylase activity
AELL_RS09060	COG1022	Amp-dependent synthetase and ligase
AELL_RS09065	COG0183	Belongs to the thiolase family
AELL_RS09070	COG1250	3-hydroxyacyl-CoA dehydrogenase
AELL_RS09070	COG1024	Enoyl-CoA hydratase
AELL_RS09075	COG1960	acyl-CoA dehydrogenase activity
AELL_RS09090	COG0217	transcriptional regulatory protein
AELL_RS09095	COG2853	Lipoprotein
AELL_RS09110	COG1611	Belongs to the LOG family
AELL_RS09115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AELL_RS09120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AELL_RS09140	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AELL_RS09155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AELL_RS09165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AELL_RS09190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AELL_RS09190	COG0475	glutathione-regulated potassium exporter activity
AELL_RS09200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AELL_RS09205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AELL_RS09205	COG2169	Transcriptional regulator
AELL_RS09210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AELL_RS09215	COG2258	MOSC domain
AELL_RS09230	COG0513	Belongs to the DEAD box helicase family
AELL_RS09235	COG1944	ATP diphosphatase activity
AELL_RS09250	COG0840	transmembrane signaling receptor activity
AELL_RS09255	COG0328	RNA-DNA hybrid ribonuclease activity
AELL_RS09260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AELL_RS09285	COG0446	pyridine nucleotide-disulphide oxidoreductase
AELL_RS09315	COG4662	Binding-protein-dependent transport system inner membrane component
AELL_RS09320	COG2998	abc-type tungstate transport system, permease component
AELL_RS09325	COG0303	'Molybdopterin
AELL_RS09335	COG2005	Transcriptional regulator
AELL_RS09345	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AELL_RS09355	COG0437	4 iron, 4 sulfur cluster binding
AELL_RS09390	COG4565	transcriptional regulatory protein
AELL_RS09395	COG0596	Alpha beta hydrolase
AELL_RS09410	COG1305	Transglutaminase-like
AELL_RS09415	COG0709	Synthesizes selenophosphate from selenide and ATP
AELL_RS09445	COG1921	L-seryl-tRNASec selenium transferase activity
AELL_RS09480	COG0745	RESPONSE REGULATOR receiver
AELL_RS09490	COG2205	protein histidine kinase activity
AELL_RS09490	COG4999	Histidine kinase
AELL_RS09490	COG3850	Histidine kinase
AELL_RS09490	COG3437	response regulator, receiver
AELL_RS09530	COG3287	FIST C domain
AELL_RS09530	COG2199	diguanylate cyclase activity
AELL_RS09530	COG2200	EAL domain
AELL_RS09545	COG1078	dGTPase activity
AELL_RS09550	COG0259	pyridoxamine-phosphate oxidase activity
AELL_RS09560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AELL_RS09570	COG0513	Belongs to the DEAD box helicase family
AELL_RS09585	COG3287	FIST C domain
AELL_RS09585	COG2200	EAL domain
AELL_RS09585	COG2199	diguanylate cyclase activity
AELL_RS09595	COG1984	allophanate hydrolase subunit 2
AELL_RS09605	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AELL_RS09630	COG0326	Molecular chaperone. Has ATPase activity
AELL_RS09645	COG3437	response regulator, receiver
AELL_RS09650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AELL_RS09660	COG3008	intermembrane lipid transfer
AELL_RS09665	COG2995	paraquat-inducible protein a
AELL_RS09690	COG2205	protein histidine kinase activity
AELL_RS09695	COG0745	RESPONSE REGULATOR receiver
AELL_RS09700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AELL_RS09720	COG2902	Dehydrogenase
AELL_RS09725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AELL_RS09730	COG4335	DNA alkylation repair
AELL_RS09745	COG0010	Belongs to the arginase family
AELL_RS09750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AELL_RS09765	COG1429	ligase activity, forming nitrogen-metal bonds
AELL_RS09770	COG1227	inorganic diphosphatase activity
AELL_RS09785	COG1027	Aspartate ammonia-lyase
AELL_RS09790	COG0745	RESPONSE REGULATOR receiver
AELL_RS09800	COG1115	amino acid carrier protein
AELL_RS09805	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AELL_RS09810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AELL_RS09815	COG1047	Peptidyl-prolyl cis-trans
AELL_RS09830	COG2193	ferroxidase activity
AELL_RS09835	COG0823	Involved in the tonB-independent uptake of proteins
AELL_RS09845	COG0848	biopolymer transport protein
AELL_RS09850	COG0811	peptide transport
AELL_RS09855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AELL_RS09860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AELL_RS09865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AELL_RS09870	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AELL_RS09875	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AELL_RS09880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AELL_RS09890	COG1475	DNA binding
AELL_RS09895	COG1192	Involved in chromosome partitioning
AELL_RS09910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AELL_RS09915	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AELL_RS09920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AELL_RS09925	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AELL_RS09930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AELL_RS09940	COG0358	DNA primase activity
AELL_RS09950	COG0571	ribonuclease III activity
AELL_RS09955	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AELL_RS09965	COG0501	Belongs to the peptidase M48B family
AELL_RS09985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AELL_RS09995	COG0706	membrane insertase activity
AELL_RS10000	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AELL_RS10005	COG0594	ribonuclease P activity
AELL_RS10010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AELL_RS10015	COG0542	response to heat
AELL_RS10030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AELL_RS10045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AELL_RS10055	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AELL_RS10060	COG0745	RESPONSE REGULATOR receiver
AELL_RS10070	COG2205	protein histidine kinase activity
AELL_RS10070	COG0784	Response regulator, receiver
AELL_RS10075	COG0179	Fumarylacetoacetate (FAA) hydrolase
AELL_RS10100	COG0138	bifunctional purine biosynthesis protein purh
AELL_RS10105	COG0004	ammonium transporteR
AELL_RS10110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AELL_RS10120	COG0739	heme binding
AELL_RS10120	COG1196	nuclear chromosome segregation
AELL_RS10120	COG0741	lytic transglycosylase activity
AELL_RS10135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AELL_RS10140	COG1917	Cupin 2, conserved barrel domain protein
AELL_RS10150	COG0302	gtp cyclohydrolase
AELL_RS10155	COG0598	Magnesium transport protein CorA
AELL_RS10180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AELL_RS10215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AELL_RS10220	COG3422	double-strand break repair
AELL_RS10245	COG1196	nuclear chromosome segregation
AELL_RS10260	COG0242	peptide deformylase activity
AELL_RS10265	COG0740	serine-type endopeptidase activity
AELL_RS10270	COG0544	peptidyl-prolyl cis-trans isomerase activity
AELL_RS10280	COG2326	polyphosphate kinase activity
AELL_RS10295	COG1773	rubredoxin
AELL_RS10310	COG4974	Belongs to the 'phage' integrase family
AELL_RS10355	COG2378	regulation of single-species biofilm formation
AELL_RS10455	COG1309	transcriptional regulator
AELL_RS10495	COG0582	viral genome integration into host DNA
AELL_RS10520	COG0626	cystathionine gamma-synthase activity
AELL_RS10535	COG0840	transmembrane signaling receptor activity
AELL_RS10545	COG0583	DNA-binding transcription factor activity
AELL_RS10580	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AELL_RS10595	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AELL_RS10600	COG1301	dicarboxylic acid transport
AELL_RS10605	COG1028	Short-chain dehydrogenase reductase Sdr
AELL_RS10620	COG1858	cytochrome C peroxidase
AELL_RS10650	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AELL_RS10655	COG0840	transmembrane signaling receptor activity
AELL_RS10665	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AELL_RS10670	COG0450	alkyl hydroperoxide reductase
AELL_RS10675	COG3118	belongs to the thioredoxin family
AELL_RS10680	COG0668	transmembrane transport
AELL_RS10685	COG5002	protein histidine kinase activity
AELL_RS10710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AELL_RS10725	COG0348	domain, Protein
AELL_RS10735	COG4753	response regulator
AELL_RS10735	COG2207	Transcriptional regulator
AELL_RS10750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AELL_RS10775	COG0716	FMN binding
AELL_RS10790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AELL_RS10805	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AELL_RS10810	COG0159	tryptophan synthase activity
AELL_RS10815	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AELL_RS10820	COG2255	four-way junction helicase activity
AELL_RS10825	COG0628	permease
AELL_RS10835	COG4628	conserved protein (DUF2132)
AELL_RS10865	COG1942	4-Oxalocrotonate Tautomerase
AELL_RS10895	COG0731	radical SAM domain protein
AELL_RS10900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AELL_RS10910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AELL_RS10925	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AELL_RS10935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AELL_RS10945	COG0463	Glycosyl transferase, family 2
AELL_RS10950	COG0726	polysaccharide deacetylase
AELL_RS10970	COG0726	polysaccharide deacetylase
AELL_RS10980	COG1696	Membrane protein involved in D-alanine export
AELL_RS10990	COG0438	transferase activity, transferring glycosyl groups
AELL_RS11010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AELL_RS11020	COG0493	'glutamate synthase
AELL_RS11025	COG0070	glutamate synthase
AELL_RS11025	COG0067	glutamate synthase
AELL_RS11025	COG0069	glutamate synthase activity
AELL_RS11040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AELL_RS11045	COG0584	glycerophosphoryl diester phosphodiesterase
AELL_RS11055	COG0745	RESPONSE REGULATOR receiver
AELL_RS11090	COG0745	RESPONSE REGULATOR receiver
AELL_RS11100	COG0840	transmembrane signaling receptor activity
AELL_RS11105	COG0840	transmembrane signaling receptor activity
AELL_RS11110	COG3437	response regulator, receiver
AELL_RS11110	COG0784	Response regulator, receiver
AELL_RS11115	COG0840	transmembrane signaling receptor activity
AELL_RS11225	COG1086	Polysaccharide biosynthesis protein
AELL_RS11230	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AELL_RS11245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AELL_RS11280	COG1216	Glycosyl transferase, family 2
AELL_RS11315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AELL_RS11320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AELL_RS11340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AELL_RS11415	COG0582	viral genome integration into host DNA
AELL_RS11450	COG2026	Addiction module toxin, RelE StbE family
AELL_RS11460	COG0582	viral genome integration into host DNA
AELL_RS11475	COG0284	orotidine-5'-phosphate decarboxylase activity
AELL_RS11480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AELL_RS11485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AELL_RS11490	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AELL_RS11510	COG0697	spore germination
AELL_RS11515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AELL_RS11530	COG1450	Type ii and iii secretion system protein
AELL_RS11535	COG1739	Uncharacterized protein family UPF0029
AELL_RS11545	COG0196	riboflavin kinase activity
AELL_RS11550	COG2226	methyltransferase
AELL_RS11555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AELL_RS11565	COG0277	FAD linked oxidase domain protein
AELL_RS11610	COG0542	response to heat
AELL_RS11615	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AELL_RS11620	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AELL_RS11635	COG2030	dehydratase
AELL_RS11655	COG0840	transmembrane signaling receptor activity
AELL_RS11660	COG1970	mechanosensitive ion channel activity
AELL_RS11665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AELL_RS11695	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AELL_RS11700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AELL_RS11705	COG1157	protein secretion by the type III secretion system
AELL_RS11715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AELL_RS11735	COG1677	Flagellar hook-basal body complex protein FliE
AELL_RS11745	COG0455	bacterial-type flagellum organization
AELL_RS11750	COG1419	protein localization to endoplasmic reticulum
AELL_RS11775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AELL_RS11800	COG1749	Flagellar hook protein flgE
AELL_RS11815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AELL_RS11825	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AELL_RS11830	COG1766	The M ring may be actively involved in energy transduction
AELL_RS11835	COG1815	bacterial-type flagellum-dependent cell motility
AELL_RS11840	COG4786	Flagellar basal body rod
AELL_RS11850	COG0745	RESPONSE REGULATOR receiver
AELL_RS11870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AELL_RS11880	COG0228	four-way junction DNA binding
AELL_RS11885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AELL_RS11890	COG0564	pseudouridine synthase activity
AELL_RS11895	COG1519	Transferase
AELL_RS11905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AELL_RS11910	COG0752	glycyl-tRNA synthetase alpha subunit
AELL_RS11920	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AELL_RS11930	COG0826	peptidase U32
AELL_RS11935	COG0840	transmembrane signaling receptor activity
AELL_RS11935	COG0840	transmembrane signaling receptor activity
AELL_RS11940	COG0497	DNA recombination
AELL_RS11945	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AELL_RS11950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AELL_RS11955	COG0049	tRNA binding
AELL_RS11960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AELL_RS11965	COG2814	Major facilitator Superfamily
AELL_RS11975	COG0840	transmembrane signaling receptor activity
AELL_RS12000	COG0310	cobalt ion transport
AELL_RS12030	COG0077	Prephenate dehydratase
AELL_RS12030	COG1605	Chorismate mutase
AELL_RS12040	COG0840	transmembrane signaling receptor activity
AELL_RS12045	COG0840	transmembrane signaling receptor activity
AELL_RS12050	COG0840	transmembrane signaling receptor activity
AELL_RS12055	COG1028	Short-chain dehydrogenase reductase Sdr
AELL_RS12070	COG2932	Transcriptional regulator
AELL_RS12145	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AELL_RS12215	COG0582	viral genome integration into host DNA
AELL_RS12230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AELL_RS12235	COG0085	RNA polymerase activity
AELL_RS12240	COG0222	ribosome binding
AELL_RS12245	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AELL_RS12250	COG0081	regulation of translation
AELL_RS12255	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AELL_RS12260	COG0250	Participates in transcription elongation, termination and antitermination
AELL_RS12275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AELL_RS12280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AELL_RS12305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AELL_RS12310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AELL_RS12315	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AELL_RS12320	COG0444	Belongs to the ABC transporter superfamily
AELL_RS12325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AELL_RS12330	COG0174	glutamine synthetase
AELL_RS12340	COG0314	molybdopterin synthase activity
AELL_RS12350	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AELL_RS12355	COG1968	undecaprenyl-diphosphatase activity
AELL_RS12365	COG0772	Belongs to the SEDS family
AELL_RS12370	COG0768	penicillin binding
AELL_RS12375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AELL_RS12420	COG1840	ABC-type Fe3 transport system, periplasmic component
AELL_RS12425	COG1178	ABC-type Fe3 transport system permease component
AELL_RS12430	COG3842	ATPase activity
AELL_RS12435	COG3706	GGDEF domain
AELL_RS12465	COG2183	response to ionizing radiation
AELL_RS12475	COG5001	Diguanylate cyclase
AELL_RS12475	COG5002	protein histidine kinase activity
AELL_RS12480	COG0251	oxidation-reduction process
AELL_RS12495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AELL_RS12505	COG0586	Pfam SNARE associated Golgi protein
AELL_RS12515	COG0335	large ribosomal subunit rRNA binding
AELL_RS12520	COG0336	Belongs to the RNA methyltransferase TrmD family
AELL_RS12530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AELL_RS12535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AELL_RS12540	COG0356	it plays a direct role in the translocation of protons across the membrane
AELL_RS12550	COG1074	ATP-dependent DNA helicase activity
AELL_RS12555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AELL_RS12560	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AELL_RS12570	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AELL_RS12585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AELL_RS12600	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AELL_RS12610	COG0602	queuosine metabolic process
AELL_RS12620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AELL_RS12625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AELL_RS12630	COG0825	malonyl-CoA metabolic process
AELL_RS12635	COG0537	adenosine 5'-monophosphoramidase activity
AELL_RS12640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AELL_RS12645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AELL_RS12645	COG0072	phenylalanine-tRNA ligase activity
AELL_RS12650	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AELL_RS12655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AELL_RS12660	COG1185	polyribonucleotide nucleotidyltransferase activity
AELL_RS12660	COG0539	negative regulation of cytoplasmic translation
AELL_RS12665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AELL_RS12670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AELL_RS12675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AELL_RS12675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AELL_RS12680	COG0779	Required for maturation of 30S ribosomal subunits
AELL_RS12685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AELL_RS12690	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AELL_RS12700	COG0083	homoserine kinase activity
AELL_RS12710	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AELL_RS12720	COG2404	hydrolase activity, acting on ester bonds
AELL_RS12725	COG0157	Belongs to the NadC ModD family
AELL_RS12735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AELL_RS12745	COG4773	Receptor
AELL_RS12755	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AELL_RS12795	COG3278	Belongs to the heme-copper respiratory oxidase family
AELL_RS12800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AELL_RS12805	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AELL_RS12810	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AELL_RS12815	COG0210	DNA helicase
AELL_RS12825	COG1242	4 iron, 4 sulfur cluster binding
AELL_RS12830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AELL_RS12835	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AELL_RS12840	COG0492	ferredoxin-NADP+ reductase activity
AELL_RS12845	COG3118	belongs to the thioredoxin family
AELL_RS12850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AELL_RS12865	COG0791	NLP P60 protein
AELL_RS12870	COG0791	NLP P60 protein
AELL_RS12885	COG0697	spore germination
AELL_RS12890	COG0424	maF-like protein
AELL_RS12905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AELL_RS12910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AELL_RS12915	COG1605	Chorismate mutase
AELL_RS12915	COG0077	Prephenate dehydratase
AELL_RS12920	COG0019	diaminopimelate decarboxylase activity
AELL_RS12925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AELL_RS12930	COG0149	triose-phosphate isomerase activity
AELL_RS12935	COG0126	phosphoglycerate kinase activity
AELL_RS12945	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AELL_RS12955	COG0018	arginyl-trna synthetase
AELL_RS12965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AELL_RS12970	COG0204	Acyl-transferase
AELL_RS12980	COG0047	phosphoribosylformylglycinamidine synthase activity
AELL_RS12985	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AELL_RS12990	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AELL_RS12995	COG0793	Belongs to the peptidase S41A family
AELL_RS13010	COG0585	pseudouridine synthase activity
AELL_RS13030	COG1136	(ABC) transporter
AELL_RS13065	COG0129	dihydroxy-acid dehydratase activity
AELL_RS13075	COG0745	RESPONSE REGULATOR receiver
AELL_RS13080	COG0642	Histidine kinase
AELL_RS13090	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AELL_RS13095	COG0702	epimerase
AELL_RS13100	COG1492	cobalamin metabolic process
AELL_RS13105	COG2205	protein histidine kinase activity
AELL_RS13125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AELL_RS13130	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AELL_RS13140	COG2095	MarC family integral membrane protein
AELL_RS13145	COG1083	cytidylyl-transferase
AELL_RS13145	COG2755	lipolytic protein G-D-S-L family
AELL_RS13150	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AELL_RS13165	COG4232	protein-disulfide reductase activity
AELL_RS13180	COG0189	ligase activity
AELL_RS13195	COG2200	EAL domain
AELL_RS13195	COG3287	FIST C domain
AELL_RS13195	COG2199	diguanylate cyclase activity
AELL_RS13200	COG0688	phosphatidylethanolamine metabolic process
AELL_RS13210	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AELL_RS13220	COG0443	Heat shock 70 kDa protein
AELL_RS13225	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AELL_RS13235	COG2358	TRAP transporter, solute receptor (TAXI family
AELL_RS13245	COG2197	response regulator
AELL_RS13265	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AELL_RS13270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AELL_RS13275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AELL_RS13280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AELL_RS13290	COG4581	dead DEAH box helicase
AELL_RS13295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AELL_RS13325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AELL_RS13335	COG1083	cytidylyl-transferase
AELL_RS13340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AELL_RS13345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AELL_RS13350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AELL_RS13355	COG2030	dehydratase
AELL_RS13360	COG2089	acid synthase
AELL_RS13370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AELL_RS13375	COG1086	Polysaccharide biosynthesis protein
AELL_RS13385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AELL_RS13390	COG0148	phosphopyruvate hydratase activity
AELL_RS13405	COG0569	domain protein
AELL_RS13405	COG0475	glutathione-regulated potassium exporter activity
AELL_RS13410	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AELL_RS13430	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AELL_RS13440	COG1007	ATP synthesis coupled electron transport
AELL_RS13450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AELL_RS13455	COG0713	ATP synthesis coupled electron transport
AELL_RS13460	COG0839	Belongs to the complex I subunit 6 family
AELL_RS13465	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AELL_RS13470	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AELL_RS13490	COG0649	NAD binding
AELL_RS13500	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AELL_RS13505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AELL_RS13540	COG0659	secondary active sulfate transmembrane transporter activity
AELL_RS13550	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AELL_RS13555	COG1252	NADH dehydrogenase
AELL_RS13560	COG0733	neurotransmitter:sodium symporter activity
AELL_RS13570	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AELL_RS13580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AELL_RS13585	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AELL_RS13590	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AELL_RS13610	COG0445	tRNA wobble uridine modification
AELL_RS13665	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AELL_RS13685	COG0348	domain, Protein
AELL_RS13690	COG0504	CTP synthase activity
AELL_RS13695	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AELL_RS13695	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AELL_RS13710	COG0693	protein deglycase activity
AELL_RS13725	COG0587	DNA-directed DNA polymerase activity
AELL_RS13730	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AELL_RS13745	COG0315	cyclic pyranopterin monophosphate synthase activity
AELL_RS13750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AELL_RS13780	COG0670	Belongs to the BI1 family
AELL_RS13785	COG0352	thiamine-phosphate diphosphorylase activity
AELL_RS13795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AELL_RS13805	COG0233	cytoplasmic translational termination
AELL_RS13810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AELL_RS13820	COG2814	Major facilitator Superfamily
AELL_RS13825	COG3264	Mechanosensitive ion channel
AELL_RS13825	COG1196	nuclear chromosome segregation
AELL_RS13835	COG3022	response to hydroperoxide
AELL_RS13840	COG3012	SEC-C Motif Domain Protein
AELL_RS13865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AELL_RS13870	COG1012	belongs to the aldehyde dehydrogenase family
AELL_RS13880	COG1704	LemA family
AELL_RS13895	COG0546	phosphoglycolate phosphatase activity
AELL_RS13910	COG2814	Major facilitator Superfamily
AELL_RS13935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AELL_RS13940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AELL_RS13970	COG2081	HI0933 family
AELL_RS13995	COG1959	2 iron, 2 sulfur cluster binding
AELL_RS14010	COG0175	sulfate reduction
AELL_RS14015	COG0175	sulfate reduction
AELL_RS14020	COG2895	sulfate adenylyltransferase (ATP) activity
AELL_RS14030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AELL_RS14040	COG1408	metallophosphoesterase
AELL_RS14045	COG0071	Belongs to the small heat shock protein (HSP20) family
AELL_RS14065	COG0840	transmembrane signaling receptor activity
AELL_RS14070	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AELL_RS14075	COG4208	sulfate ABC transporter
AELL_RS14080	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AELL_RS14085	COG2200	EAL domain
AELL_RS14085	COG2199	diguanylate cyclase activity
AELL_RS14085	COG3287	FIST C domain
AELL_RS14090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AELL_RS14095	COG1959	2 iron, 2 sulfur cluster binding
AELL_RS14115	COG2308	Evidence 4 Homologs of previously reported genes of
AELL_RS14120	COG1217	gtp-binding protein TYPA
AELL_RS14135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AELL_RS14160	COG0745	RESPONSE REGULATOR receiver
AELL_RS14165	COG0642	Histidine kinase
AELL_RS14175	COG0425	Belongs to the sulfur carrier protein TusA family
AELL_RS14180	COG0784	Response regulator, receiver
AELL_RS14180	COG3437	response regulator, receiver
AELL_RS14185	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AELL_RS14190	COG2066	Belongs to the glutaminase family
AELL_RS14195	COG2860	membrane
AELL_RS14210	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group