locus-tag	class	description
AHALO_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AHALO_RS00010	COG0592	DNA-directed DNA polymerase activity
AHALO_RS00015	COG0187	DNA topoisomerase II activity
AHALO_RS00050	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AHALO_RS00080	COG0564	pseudouridine synthase activity
AHALO_RS00085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AHALO_RS00090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHALO_RS00095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHALO_RS00105	COG0778	Nitroreductase
AHALO_RS00115	COG1151	hydroxylamine reductase activity
AHALO_RS00135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AHALO_RS00155	COG1858	cytochrome C peroxidase
AHALO_RS00165	COG2207	Transcriptional regulator
AHALO_RS00165	COG4753	response regulator
AHALO_RS00175	COG1490	D-aminoacyl-tRNA deacylase activity
AHALO_RS00185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AHALO_RS00190	COG0348	domain, Protein
AHALO_RS00195	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AHALO_RS00200	COG3118	belongs to the thioredoxin family
AHALO_RS00205	COG1733	regulation of RNA biosynthetic process
AHALO_RS00210	COG0604	alcohol dehydrogenase
AHALO_RS00215	COG1733	regulation of RNA biosynthetic process
AHALO_RS00220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHALO_RS00225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AHALO_RS00240	COG0107	imidazoleglycerol-phosphate synthase activity
AHALO_RS00245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AHALO_RS00250	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AHALO_RS00255	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AHALO_RS00255	COG0517	IMP dehydrogenase activity
AHALO_RS00260	COG1187	pseudouridine synthase activity
AHALO_RS00265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AHALO_RS00265	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AHALO_RS00270	COG1981	membrane
AHALO_RS00275	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AHALO_RS00280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AHALO_RS00290	COG0840	transmembrane signaling receptor activity
AHALO_RS00295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AHALO_RS00300	COG0778	Nitroreductase
AHALO_RS00310	COG0367	asparagine synthase
AHALO_RS00320	COG0745	RESPONSE REGULATOR receiver
AHALO_RS00325	COG0306	phosphate transporter
AHALO_RS00335	COG0513	Belongs to the DEAD box helicase family
AHALO_RS00340	COG0439	Biotin carboxylase
AHALO_RS00345	COG0511	ligase activity, forming carbon-carbon bonds
AHALO_RS00350	COG0590	tRNA wobble adenosine to inosine editing
AHALO_RS00360	COG0247	lactate metabolic process
AHALO_RS00365	COG1139	Iron-sulfur cluster binding protein
AHALO_RS00370	COG1556	Lactate utilization protein
AHALO_RS00375	COG3852	Histidine kinase
AHALO_RS00385	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AHALO_RS00410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AHALO_RS00415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AHALO_RS00440	COG0390	transport system, permease component
AHALO_RS00445	COG0745	RESPONSE REGULATOR receiver
AHALO_RS00455	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHALO_RS00475	COG0642	Histidine kinase
AHALO_RS00480	COG0745	RESPONSE REGULATOR receiver
AHALO_RS00485	COG2353	YceI-like domain
AHALO_RS00495	COG3220	belongs to the UPF0276 family
AHALO_RS00505	COG4191	Histidine kinase
AHALO_RS00510	COG0745	RESPONSE REGULATOR receiver
AHALO_RS00525	COG0534	Mate efflux family protein
AHALO_RS00530	COG0460	homoserine dehydrogenase
AHALO_RS00535	COG0436	Aminotransferase
AHALO_RS00545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AHALO_RS00550	COG0840	transmembrane signaling receptor activity
AHALO_RS00555	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AHALO_RS00560	COG0254	rRNA binding
AHALO_RS00565	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AHALO_RS00580	COG3706	GGDEF domain
AHALO_RS00620	COG5444	nuclease activity
AHALO_RS00630	COG2239	Acts as a magnesium transporter
AHALO_RS00640	COG3706	GGDEF domain
AHALO_RS00655	COG0492	ferredoxin-NADP+ reductase activity
AHALO_RS00660	COG0450	alkyl hydroperoxide reductase
AHALO_RS00670	COG4191	Histidine kinase
AHALO_RS00680	COG5002	protein histidine kinase activity
AHALO_RS00680	COG3447	MASE1 domain protein
AHALO_RS00680	COG5001	Diguanylate cyclase
AHALO_RS00685	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AHALO_RS00690	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AHALO_RS00695	COG0237	dephospho-CoA kinase activity
AHALO_RS00700	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AHALO_RS00705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AHALO_RS00715	COG2353	YceI-like domain
AHALO_RS00720	COG1846	Transcriptional regulator
AHALO_RS00725	COG1280	lysine exporter protein (LysE YggA)
AHALO_RS00735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AHALO_RS00740	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AHALO_RS00745	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AHALO_RS00755	COG0505	Belongs to the CarA family
AHALO_RS00770	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AHALO_RS00770	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AHALO_RS00780	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AHALO_RS00785	COG0489	protein tyrosine kinase activity
AHALO_RS00795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AHALO_RS00795	COG0140	phosphoribosyl-ATP diphosphatase activity
AHALO_RS00815	COG1410	methionine synthase
AHALO_RS00815	COG0646	methionine synthase
AHALO_RS00855	COG1854	S-ribosylhomocysteine lyase activity
AHALO_RS00865	COG0546	phosphoglycolate phosphatase activity
AHALO_RS00870	COG0747	negative chemotaxis
AHALO_RS00890	COG0243	molybdopterin cofactor binding
AHALO_RS00900	COG3708	Transcriptional regulator
AHALO_RS00900	COG2207	Transcriptional regulator
AHALO_RS00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AHALO_RS00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AHALO_RS00915	COG5002	protein histidine kinase activity
AHALO_RS00915	COG3850	Histidine kinase
AHALO_RS00920	COG0745	RESPONSE REGULATOR receiver
AHALO_RS00930	COG0704	Plays a role in the regulation of phosphate uptake
AHALO_RS00935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AHALO_RS00940	COG0581	inorganic phosphate transmembrane transporter activity
AHALO_RS00945	COG0573	inorganic phosphate transmembrane transporter activity
AHALO_RS00950	COG2203	Gaf domain
AHALO_RS00950	COG2199	diguanylate cyclase activity
AHALO_RS00950	COG2200	EAL domain
AHALO_RS00960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AHALO_RS00965	COG0268	Binds directly to 16S ribosomal RNA
AHALO_RS00970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AHALO_RS00975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AHALO_RS00980	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AHALO_RS00985	COG0746	molybdenum cofactor guanylyltransferase activity
AHALO_RS01005	COG0243	molybdopterin cofactor binding
AHALO_RS01010	COG0437	4 iron, 4 sulfur cluster binding
AHALO_RS01030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AHALO_RS01035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AHALO_RS01040	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AHALO_RS01075	COG0575	Belongs to the CDS family
AHALO_RS01080	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AHALO_RS01100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AHALO_RS01105	COG0023	Translation Initiation Factor
AHALO_RS01110	COG1115	amino acid carrier protein
AHALO_RS01115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AHALO_RS01115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AHALO_RS01125	COG2022	thiamine diphosphate biosynthetic process
AHALO_RS01195	COG0745	RESPONSE REGULATOR receiver
AHALO_RS01200	COG5001	Diguanylate cyclase
AHALO_RS01200	COG4251	negative regulation of phosphorylation
AHALO_RS01200	COG3706	GGDEF domain
AHALO_RS01200	COG2203	Gaf domain
AHALO_RS01210	COG0585	pseudouridine synthase activity
AHALO_RS01230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AHALO_RS01245	COG0793	Belongs to the peptidase S41A family
AHALO_RS01250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AHALO_RS01255	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AHALO_RS01260	COG0047	phosphoribosylformylglycinamidine synthase activity
AHALO_RS01270	COG0204	Acyl-transferase
AHALO_RS01285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AHALO_RS01290	COG0018	arginyl-trna synthetase
AHALO_RS01295	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AHALO_RS01305	COG0126	phosphoglycerate kinase activity
AHALO_RS01310	COG0149	triose-phosphate isomerase activity
AHALO_RS01315	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AHALO_RS01320	COG0019	diaminopimelate decarboxylase activity
AHALO_RS01325	COG0647	UMP catabolic process
AHALO_RS01330	COG0077	Prephenate dehydratase
AHALO_RS01330	COG1605	Chorismate mutase
AHALO_RS01335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AHALO_RS01340	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AHALO_RS01345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AHALO_RS01355	COG0424	maF-like protein
AHALO_RS01380	COG0791	NLP P60 protein
AHALO_RS01390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AHALO_RS01395	COG3118	belongs to the thioredoxin family
AHALO_RS01400	COG3852	Histidine kinase
AHALO_RS01405	COG0745	RESPONSE REGULATOR receiver
AHALO_RS01410	COG1115	amino acid carrier protein
AHALO_RS01415	COG0492	ferredoxin-NADP+ reductase activity
AHALO_RS01420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AHALO_RS01425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AHALO_RS01430	COG1242	4 iron, 4 sulfur cluster binding
AHALO_RS01440	COG0210	DNA helicase
AHALO_RS01445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AHALO_RS01450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AHALO_RS01455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AHALO_RS01460	COG3278	Belongs to the heme-copper respiratory oxidase family
AHALO_RS01495	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AHALO_RS01500	COG0814	amino acid
AHALO_RS01505	COG4773	Receptor
AHALO_RS01510	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AHALO_RS01520	COG4773	Receptor
AHALO_RS01530	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AHALO_RS01540	COG0157	Belongs to the NadC ModD family
AHALO_RS01545	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AHALO_RS01555	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AHALO_RS01565	COG0083	homoserine kinase activity
AHALO_RS01575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AHALO_RS01580	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AHALO_RS01585	COG0779	Required for maturation of 30S ribosomal subunits
AHALO_RS01590	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AHALO_RS01590	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AHALO_RS01595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AHALO_RS01600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AHALO_RS01605	COG1185	polyribonucleotide nucleotidyltransferase activity
AHALO_RS01605	COG0539	negative regulation of cytoplasmic translation
AHALO_RS01610	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AHALO_RS01615	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AHALO_RS01620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHALO_RS01620	COG0072	phenylalanine-tRNA ligase activity
AHALO_RS01625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AHALO_RS01630	COG0537	adenosine 5'-monophosphoramidase activity
AHALO_RS01635	COG0825	malonyl-CoA metabolic process
AHALO_RS01640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AHALO_RS01645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AHALO_RS01675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AHALO_RS01680	COG0303	'Molybdopterin
AHALO_RS01705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AHALO_RS01715	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AHALO_RS01720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AHALO_RS01725	COG3706	GGDEF domain
AHALO_RS01735	COG0840	transmembrane signaling receptor activity
AHALO_RS01740	COG0352	thiamine-phosphate diphosphorylase activity
AHALO_RS01750	COG0840	transmembrane signaling receptor activity
AHALO_RS01755	COG0356	it plays a direct role in the translocation of protons across the membrane
AHALO_RS01760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AHALO_RS01765	COG0336	Belongs to the RNA methyltransferase TrmD family
AHALO_RS01770	COG0335	large ribosomal subunit rRNA binding
AHALO_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
AHALO_RS01800	COG2966	Psort location CytoplasmicMembrane, score
AHALO_RS01815	COG3706	GGDEF domain
AHALO_RS01815	COG2203	Gaf domain
AHALO_RS01815	COG5001	Diguanylate cyclase
AHALO_RS01815	COG4251	negative regulation of phosphorylation
AHALO_RS01825	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AHALO_RS01830	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AHALO_RS01870	COG1971	Probably functions as a manganese efflux pump
AHALO_RS01880	COG2814	Major facilitator Superfamily
AHALO_RS01885	COG1132	(ABC) transporter
AHALO_RS01890	COG1132	(ABC) transporter
AHALO_RS01895	COG4771	TonB-dependent receptor
AHALO_RS01905	COG4771	TonB-dependent receptor
AHALO_RS01915	COG1629	transport
AHALO_RS01920	COG0784	Response regulator, receiver
AHALO_RS01940	COG0848	biopolymer transport protein
AHALO_RS01945	COG0811	peptide transport
AHALO_RS01950	COG0811	peptide transport
AHALO_RS01975	COG4774	siderophore transport
AHALO_RS01985	COG4774	siderophore transport
AHALO_RS02005	COG4753	response regulator
AHALO_RS02005	COG2207	Transcriptional regulator
AHALO_RS02030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AHALO_RS02055	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AHALO_RS02060	COG1333	cytochrome c biogenesis protein
AHALO_RS02060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AHALO_RS02065	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AHALO_RS02070	COG3005	denitrification pathway
AHALO_RS02080	COG0840	transmembrane signaling receptor activity
AHALO_RS02100	COG3043	anaerobic respiration
AHALO_RS02105	COG0348	domain, Protein
AHALO_RS02110	COG0437	4 iron, 4 sulfur cluster binding
AHALO_RS02115	COG0243	molybdopterin cofactor binding
AHALO_RS02135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AHALO_RS02145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AHALO_RS02155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AHALO_RS02165	COG2404	hydrolase activity, acting on ester bonds
AHALO_RS02180	COG1832	CoA-binding protein
AHALO_RS02185	COG0642	Histidine kinase
AHALO_RS02190	COG0745	RESPONSE REGULATOR receiver
AHALO_RS02195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AHALO_RS02200	COG0191	fructose-bisphosphate aldolase activity
AHALO_RS02205	COG0848	biopolymer transport protein
AHALO_RS02210	COG0811	peptide transport
AHALO_RS02225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AHALO_RS02230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AHALO_RS02240	COG0142	geranyltranstransferase activity
AHALO_RS02245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AHALO_RS02250	COG0442	prolyl-tRNA aminoacylation
AHALO_RS02255	COG0668	transmembrane transport
AHALO_RS02260	COG0617	tRNA 3'-terminal CCA addition
AHALO_RS02265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AHALO_RS02270	COG1862	Preprotein translocase
AHALO_RS02275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AHALO_RS02280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AHALO_RS02300	COG0495	leucyl-tRNA aminoacylation
AHALO_RS02310	COG0285	dihydrofolate synthase activity
AHALO_RS02315	COG0739	heme binding
AHALO_RS02345	COG1136	(ABC) transporter
AHALO_RS02345	COG0577	efflux transmembrane transporter activity
AHALO_RS02350	COG1136	(ABC) transporter
AHALO_RS02350	COG0577	efflux transmembrane transporter activity
AHALO_RS02375	COG0784	Response regulator, receiver
AHALO_RS02400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AHALO_RS02405	COG2986	histidine ammonia-lyase
AHALO_RS02420	COG1053	succinate dehydrogenase
AHALO_RS02420	COG3976	FMN-binding domain protein
AHALO_RS02425	COG3852	Histidine kinase
AHALO_RS02430	COG0745	RESPONSE REGULATOR receiver
AHALO_RS02440	COG0745	RESPONSE REGULATOR receiver
AHALO_RS02455	COG0745	RESPONSE REGULATOR receiver
AHALO_RS02460	COG0642	Histidine kinase
AHALO_RS02465	COG2081	HI0933 family
AHALO_RS02470	COG0840	transmembrane signaling receptor activity
AHALO_RS02475	COG2204	response regulator
AHALO_RS02480	COG0840	transmembrane signaling receptor activity
AHALO_RS02490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AHALO_RS02495	COG1692	metallophosphoesterase
AHALO_RS02515	COG2226	methyltransferase
AHALO_RS02520	COG1570	exodeoxyribonuclease VII activity
AHALO_RS02530	COG0840	transmembrane signaling receptor activity
AHALO_RS02535	COG0835	chemotaxis
AHALO_RS02540	COG0745	RESPONSE REGULATOR receiver
AHALO_RS02545	COG2201	protein-glutamate methylesterase activity
AHALO_RS02550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AHALO_RS02560	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AHALO_RS02565	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AHALO_RS02580	COG0459	protein refolding
AHALO_RS02620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AHALO_RS02625	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AHALO_RS02630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AHALO_RS02635	COG0352	thiamine-phosphate diphosphorylase activity
AHALO_RS02640	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AHALO_RS02655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AHALO_RS02660	COG2264	protein methyltransferase activity
AHALO_RS02665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHALO_RS02675	COG0784	Response regulator, receiver
AHALO_RS02675	COG3437	response regulator, receiver
AHALO_RS02680	COG0745	RESPONSE REGULATOR receiver
AHALO_RS02695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHALO_RS02700	COG0475	glutathione-regulated potassium exporter activity
AHALO_RS02700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AHALO_RS02720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AHALO_RS02730	COG1309	transcriptional regulator
AHALO_RS02740	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AHALO_RS02745	COG1090	epimerase
AHALO_RS02750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AHALO_RS02765	COG0481	GTPase activity
AHALO_RS02775	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AHALO_RS02780	COG0482	sulfurtransferase activity
AHALO_RS02785	COG0482	sulfurtransferase activity
AHALO_RS02790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AHALO_RS02795	COG0006	proline dipeptidase activity
AHALO_RS02800	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AHALO_RS02805	COG0402	S-adenosylhomocysteine deaminase activity
AHALO_RS02810	COG0616	signal peptide processing
AHALO_RS02815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AHALO_RS02820	COG0280	phosphate acetyltransferase
AHALO_RS02825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AHALO_RS02830	COG2176	DNA-directed DNA polymerase activity
AHALO_RS02850	COG2176	DNA-directed DNA polymerase activity
AHALO_RS02870	COG0745	RESPONSE REGULATOR receiver
AHALO_RS02875	COG0642	Histidine kinase
AHALO_RS02940	COG1546	Belongs to the CinA family
AHALO_RS02940	COG1058	Belongs to the CinA family
AHALO_RS02945	COG0579	oxidoreductase
AHALO_RS02950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AHALO_RS02965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AHALO_RS02990	COG0714	Associated with various cellular activities
AHALO_RS03000	COG4175	Glycine betaine
AHALO_RS03005	COG4176	ABC-type proline glycine betaine transport system permease component
AHALO_RS03010	COG2113	Glycine betaine
AHALO_RS03015	COG0052	Belongs to the universal ribosomal protein uS2 family
AHALO_RS03020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AHALO_RS03025	COG1136	(ABC) transporter
AHALO_RS03035	COG0194	GDP metabolic process
AHALO_RS03040	COG2200	EAL domain
AHALO_RS03040	COG3287	FIST C domain
AHALO_RS03040	COG2199	diguanylate cyclase activity
AHALO_RS03045	COG0252	asparaginase activity
AHALO_RS03050	COG2217	Heavy metal translocating P-type atpase
AHALO_RS03060	COG2863	cytochrome
AHALO_RS03065	COG1132	(ABC) transporter
AHALO_RS03070	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AHALO_RS03075	COG2078	PFAM AMMECR1 domain protein
AHALO_RS03080	COG3437	response regulator, receiver
AHALO_RS03080	COG0784	Response regulator, receiver
AHALO_RS03085	COG1355	regulation of microtubule-based process
AHALO_RS03090	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AHALO_RS03095	COG1121	(ABC) transporter
AHALO_RS03100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AHALO_RS03105	COG2996	Protein conserved in bacteria
AHALO_RS03110	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AHALO_RS03120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AHALO_RS03125	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AHALO_RS03130	COG1028	Short-chain dehydrogenase reductase Sdr
AHALO_RS03155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AHALO_RS03165	COG0210	DNA helicase
AHALO_RS03170	COG2199	diguanylate cyclase activity
AHALO_RS03175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AHALO_RS03215	COG0737	Belongs to the 5'-nucleotidase family
AHALO_RS03245	COG0525	valine-tRNA ligase activity
AHALO_RS03265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHALO_RS03275	COG3852	Histidine kinase
AHALO_RS03305	COG2814	Major facilitator Superfamily
AHALO_RS03310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AHALO_RS03330	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AHALO_RS03335	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AHALO_RS03340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AHALO_RS03355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHALO_RS03370	COG0840	transmembrane signaling receptor activity
AHALO_RS03375	COG0840	transmembrane signaling receptor activity
AHALO_RS03380	COG2217	Heavy metal translocating P-type atpase
AHALO_RS03385	COG0640	Transcriptional regulator
AHALO_RS03455	COG0732	type I restriction modification DNA specificity domain
AHALO_RS03515	COG0450	alkyl hydroperoxide reductase
AHALO_RS03520	COG2354	Protein conserved in bacteria
AHALO_RS03530	COG1124	(ABC) transporter
AHALO_RS03545	COG0601	transmembrane transport
AHALO_RS03550	COG0747	negative chemotaxis
AHALO_RS03565	COG0840	transmembrane signaling receptor activity
AHALO_RS03570	COG0840	transmembrane signaling receptor activity
AHALO_RS03575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AHALO_RS03605	COG1858	cytochrome C peroxidase
AHALO_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
AHALO_RS03630	COG2207	Transcriptional regulator
AHALO_RS03630	COG1917	Cupin 2, conserved barrel domain protein
AHALO_RS03640	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AHALO_RS03645	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AHALO_RS03660	COG0626	cystathionine gamma-synthase activity
AHALO_RS03665	COG1242	4 iron, 4 sulfur cluster binding
AHALO_RS03670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AHALO_RS03715	COG2151	metal-sulfur cluster biosynthetic enzyme
AHALO_RS03720	COG2166	iron-sulfur cluster assembly
AHALO_RS03725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AHALO_RS03730	COG0719	Fe-S assembly protein
AHALO_RS03735	COG0396	ATPase activity
AHALO_RS03740	COG0719	Fe-S assembly protein
AHALO_RS03745	COG0765	amino acid transport
AHALO_RS03750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHALO_RS03760	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AHALO_RS03760	COG0822	iron-sulfur transferase activity
AHALO_RS03760	COG2906	2 iron, 2 sulfur cluster binding
AHALO_RS03780	COG0165	Argininosuccinate lyase
AHALO_RS03785	COG0784	Response regulator, receiver
AHALO_RS03785	COG0835	chemotaxis
AHALO_RS03790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AHALO_RS03795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AHALO_RS03800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AHALO_RS03815	COG0556	nucleotide-excision repair
AHALO_RS03835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AHALO_RS03860	COG0698	ribose 5-phosphate isomerase
AHALO_RS03865	COG0681	Belongs to the peptidase S26 family
AHALO_RS03870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AHALO_RS03880	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AHALO_RS03885	COG0193	aminoacyl-tRNA hydrolase activity
AHALO_RS03900	COG0860	N-Acetylmuramoyl-L-alanine amidase
AHALO_RS03910	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AHALO_RS03920	COG1758	RNA polymerase activity
AHALO_RS03925	COG0528	UMP kinase activity
AHALO_RS03935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AHALO_RS03940	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AHALO_RS03945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AHALO_RS03955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AHALO_RS03960	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AHALO_RS03970	COG4191	Histidine kinase
AHALO_RS03975	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AHALO_RS03980	COG0305	Participates in initiation and elongation during chromosome replication
AHALO_RS03990	COG0166	Belongs to the GPI family
AHALO_RS04010	COG1943	Transposase
AHALO_RS04015	COG1793	dna ligase
AHALO_RS04020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AHALO_RS04025	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AHALO_RS04025	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AHALO_RS04030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AHALO_RS04040	COG0133	tryptophan synthase activity
AHALO_RS04050	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AHALO_RS04065	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AHALO_RS04085	COG0175	sulfate reduction
AHALO_RS04090	COG2895	sulfate adenylyltransferase (ATP) activity
AHALO_RS04100	COG0529	Catalyzes the synthesis of activated sulfate
AHALO_RS04155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AHALO_RS04160	COG0110	maltose O-acetyltransferase activity
AHALO_RS04170	COG2030	dehydratase
AHALO_RS04175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AHALO_RS04180	COG1086	Polysaccharide biosynthesis protein
AHALO_RS04185	COG0012	GTP binding
AHALO_RS04205	COG3123	guanosine phosphorylase activity
AHALO_RS04225	COG4139	cobalamin transport
AHALO_RS04230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AHALO_RS04245	COG0585	pseudouridine synthase activity
AHALO_RS04255	COG0840	transmembrane signaling receptor activity
AHALO_RS04260	COG0632	four-way junction helicase activity
AHALO_RS04265	COG1181	Belongs to the D-alanine--D-alanine ligase family
AHALO_RS04275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AHALO_RS04295	COG0581	inorganic phosphate transmembrane transporter activity
AHALO_RS04295	COG0573	inorganic phosphate transmembrane transporter activity
AHALO_RS04300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AHALO_RS04310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AHALO_RS04325	COG0051	transcription antitermination factor activity, RNA binding
AHALO_RS04330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AHALO_RS04335	COG0088	Forms part of the polypeptide exit tunnel
AHALO_RS04340	COG0089	rRNA binding
AHALO_RS04345	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AHALO_RS04350	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AHALO_RS04355	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AHALO_RS04360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AHALO_RS04365	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AHALO_RS04370	COG0255	Belongs to the universal ribosomal protein uL29 family
AHALO_RS04375	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AHALO_RS04380	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AHALO_RS04385	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AHALO_RS04390	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AHALO_RS04395	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AHALO_RS04400	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AHALO_RS04405	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AHALO_RS04415	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AHALO_RS04420	COG0200	Binds to the 23S rRNA
AHALO_RS04425	COG0201	protein transport
AHALO_RS04430	COG0024	Methionine aminopeptidase
AHALO_RS04435	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AHALO_RS04460	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AHALO_RS04475	COG1032	radical SAM domain protein
AHALO_RS04480	COG0563	adenylate kinase activity
AHALO_RS04495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AHALO_RS04500	COG0322	excinuclease ABC activity
AHALO_RS04540	COG0484	heat shock protein binding
AHALO_RS04550	COG0840	transmembrane signaling receptor activity
AHALO_RS04575	COG0724	RNA recognition motif
AHALO_RS04580	COG0708	Exodeoxyribonuclease III
AHALO_RS04605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AHALO_RS04610	COG0765	amino acid transport
AHALO_RS04625	COG1528	Iron-storage protein
AHALO_RS04630	COG1227	inorganic diphosphatase activity
AHALO_RS04635	COG0010	Belongs to the arginase family
AHALO_RS04655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AHALO_RS04680	COG0702	epimerase
AHALO_RS04685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHALO_RS04705	COG0326	Molecular chaperone. Has ATPase activity
AHALO_RS04730	COG0583	DNA-binding transcription factor activity
AHALO_RS04735	COG0326	Molecular chaperone. Has ATPase activity
AHALO_RS04745	COG2358	TRAP transporter, solute receptor (TAXI family
AHALO_RS04775	COG0840	transmembrane signaling receptor activity
AHALO_RS04780	COG0840	transmembrane signaling receptor activity
AHALO_RS04785	COG2207	Transcriptional regulator
AHALO_RS04785	COG4753	response regulator
AHALO_RS04790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AHALO_RS04805	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AHALO_RS04810	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AHALO_RS04815	COG1984	allophanate hydrolase subunit 2
AHALO_RS04850	COG2183	response to ionizing radiation
AHALO_RS04855	COG0840	transmembrane signaling receptor activity
AHALO_RS04860	COG0513	Belongs to the DEAD box helicase family
AHALO_RS04870	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AHALO_RS04885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AHALO_RS04890	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AHALO_RS04895	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AHALO_RS04925	COG1921	L-seryl-tRNASec selenium transferase activity
AHALO_RS04930	COG0709	Synthesizes selenophosphate from selenide and ATP
AHALO_RS04935	COG1305	Transglutaminase-like
AHALO_RS04950	COG2204	response regulator
AHALO_RS04990	COG0437	4 iron, 4 sulfur cluster binding
AHALO_RS05010	COG3383	formate dehydrogenase (NAD+) activity
AHALO_RS05015	COG0243	molybdopterin cofactor binding
AHALO_RS05015	COG3383	formate dehydrogenase (NAD+) activity
AHALO_RS05020	COG0437	4 iron, 4 sulfur cluster binding
AHALO_RS05030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AHALO_RS05045	COG1104	cysteine desulfurase activity
AHALO_RS05050	COG0303	'Molybdopterin
AHALO_RS05055	COG2998	abc-type tungstate transport system, permease component
AHALO_RS05060	COG4662	Binding-protein-dependent transport system inner membrane component
AHALO_RS05070	COG0725	ABC transporter, periplasmic molybdate-binding protein
AHALO_RS05075	COG3842	ATPase activity
AHALO_RS05080	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AHALO_RS05090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AHALO_RS05095	COG1120	ATPase activity
AHALO_RS05115	COG4771	TonB-dependent receptor
AHALO_RS05120	COG0596	Alpha beta hydrolase
AHALO_RS05130	COG3383	formate dehydrogenase (NAD+) activity
AHALO_RS05135	COG3383	formate dehydrogenase (NAD+) activity
AHALO_RS05140	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AHALO_RS05145	COG0651	ATP synthesis coupled electron transport
AHALO_RS05150	COG0650	Formate hydrogenlyase subunit 4
AHALO_RS05155	COG4237	Hydrogenase 4 membrane
AHALO_RS05160	COG0651	ATP synthesis coupled electron transport
AHALO_RS05165	COG3261	NADH dehydrogenase
AHALO_RS05165	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AHALO_RS05175	COG3260	NADH ubiquinone oxidoreductase 20
AHALO_RS05190	COG2116	formate transmembrane transporter activity
AHALO_RS05195	COG3383	formate dehydrogenase (NAD+) activity
AHALO_RS05200	COG3383	formate dehydrogenase (NAD+) activity
AHALO_RS05215	COG1472	Belongs to the glycosyl hydrolase 3 family
AHALO_RS05235	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AHALO_RS05265	COG0492	ferredoxin-NADP+ reductase activity
AHALO_RS05270	COG0475	glutathione-regulated potassium exporter activity
AHALO_RS05270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AHALO_RS05280	COG0693	protein deglycase activity
AHALO_RS05290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AHALO_RS05305	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AHALO_RS05310	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AHALO_RS05320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AHALO_RS05330	COG0439	Biotin carboxylase
AHALO_RS05335	COG0288	reversible hydration of carbon dioxide
AHALO_RS05440	COG0745	RESPONSE REGULATOR receiver
AHALO_RS05445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AHALO_RS05455	COG1611	Belongs to the LOG family
AHALO_RS05475	COG0739	heme binding
AHALO_RS05480	COG1027	Aspartate ammonia-lyase
AHALO_RS05485	COG0217	transcriptional regulatory protein
AHALO_RS05495	COG4783	chaperone-mediated protein folding
AHALO_RS05500	COG0697	spore germination
AHALO_RS05510	COG1960	acyl-CoA dehydrogenase activity
AHALO_RS05515	COG1049	propionate catabolic process, 2-methylcitrate cycle
AHALO_RS05525	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AHALO_RS05535	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AHALO_RS05540	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AHALO_RS05545	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AHALO_RS05550	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AHALO_RS05555	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AHALO_RS05560	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AHALO_RS05565	COG0733	neurotransmitter:sodium symporter activity
AHALO_RS05570	COG2814	Major facilitator Superfamily
AHALO_RS05575	COG0840	transmembrane signaling receptor activity
AHALO_RS05585	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AHALO_RS05590	COG0298	carbon dioxide binding
AHALO_RS05595	COG0409	Hydrogenase expression formation protein
AHALO_RS05600	COG0309	Hydrogenase expression formation protein (HypE)
AHALO_RS05605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AHALO_RS05605	COG1024	Enoyl-CoA hydratase
AHALO_RS05610	COG0375	protein maturation
AHALO_RS05615	COG3706	GGDEF domain
AHALO_RS05625	COG1648	precorrin-2 dehydrogenase activity
AHALO_RS05625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AHALO_RS05645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AHALO_RS05650	COG2171	N-acyltransferase activity
AHALO_RS05660	COG1047	Peptidyl-prolyl cis-trans
AHALO_RS05680	COG2884	Cell division ATP-binding protein ftsE
AHALO_RS05685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AHALO_RS05695	COG0564	pseudouridine synthase activity
AHALO_RS05700	COG0772	Belongs to the SEDS family
AHALO_RS05710	COG3706	GGDEF domain
AHALO_RS05720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AHALO_RS05740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AHALO_RS05745	COG0066	3-isopropylmalate dehydratase activity
AHALO_RS05750	COG0473	3-isopropylmalate dehydrogenase activity
AHALO_RS05770	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AHALO_RS05775	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AHALO_RS05780	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AHALO_RS05785	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AHALO_RS05790	COG0202	RNA polymerase activity
AHALO_RS05795	COG0203	ribosomal protein L17
AHALO_RS05800	COG0154	amidase activity
AHALO_RS05805	COG0517	IMP dehydrogenase activity
AHALO_RS05805	COG0516	GMP reductase activity
AHALO_RS05855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AHALO_RS05865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AHALO_RS05870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AHALO_RS05885	COG0420	3'-5' exonuclease activity
AHALO_RS05890	COG0419	ATPase involved in DNA repair
AHALO_RS05900	COG1074	ATP-dependent DNA helicase activity
AHALO_RS05910	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AHALO_RS05930	COG2084	Dehydrogenase
AHALO_RS05940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AHALO_RS05945	COG0251	oxidation-reduction process
AHALO_RS05960	COG1846	Transcriptional regulator
AHALO_RS05980	COG1309	transcriptional regulator
AHALO_RS05985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AHALO_RS05990	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AHALO_RS06000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AHALO_RS06005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHALO_RS06015	COG0521	Mo-molybdopterin cofactor biosynthetic process
AHALO_RS06020	COG0471	metal ion transport
AHALO_RS06025	COG1193	negative regulation of DNA recombination
AHALO_RS06030	COG0668	transmembrane transport
AHALO_RS06045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AHALO_RS06070	COG0454	-acetyltransferase
AHALO_RS06085	COG1794	racemase activity, acting on amino acids and derivatives
AHALO_RS06090	COG1742	UPF0060 membrane protein
AHALO_RS06100	COG1917	Cupin 2, conserved barrel domain protein
AHALO_RS06100	COG2207	Transcriptional regulator
AHALO_RS06115	COG2258	MOSC domain
AHALO_RS06120	COG2824	Alkylphosphonate utilization operon protein PhnA
AHALO_RS06175	COG1733	regulation of RNA biosynthetic process
AHALO_RS06180	COG2249	NAD(P)H dehydrogenase (quinone) activity
AHALO_RS06190	COG0778	Nitroreductase
AHALO_RS06200	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AHALO_RS06210	COG0840	transmembrane signaling receptor activity
AHALO_RS06215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AHALO_RS06245	COG3046	protein related to deoxyribodipyrimidine photolyase
AHALO_RS06250	COG2200	EAL domain
AHALO_RS06255	COG0352	thiamine-phosphate diphosphorylase activity
AHALO_RS06260	COG0157	Belongs to the NadC ModD family
AHALO_RS06275	COG3842	ATPase activity
AHALO_RS06305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AHALO_RS06315	COG0488	(ABC) transporter
AHALO_RS06325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AHALO_RS06345	COG1607	acyl-coa hydrolase
AHALO_RS06355	COG4999	Histidine kinase
AHALO_RS06355	COG3437	response regulator, receiver
AHALO_RS06355	COG2205	protein histidine kinase activity
AHALO_RS06355	COG3850	Histidine kinase
AHALO_RS06360	COG1607	acyl-coa hydrolase
AHALO_RS06365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AHALO_RS06375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AHALO_RS06380	COG0840	transmembrane signaling receptor activity
AHALO_RS06385	COG0114	fumarate hydratase activity
AHALO_RS06405	COG2030	dehydratase
AHALO_RS06425	COG2195	Cleaves the N-terminal amino acid of tripeptides
AHALO_RS06435	COG2200	EAL domain
AHALO_RS06435	COG3287	FIST C domain
AHALO_RS06435	COG2199	diguanylate cyclase activity
AHALO_RS06440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AHALO_RS06440	COG1333	cytochrome c biogenesis protein
AHALO_RS06445	COG0500	methyltransferase
AHALO_RS06450	COG4251	negative regulation of phosphorylation
AHALO_RS06450	COG5001	Diguanylate cyclase
AHALO_RS06450	COG3706	GGDEF domain
AHALO_RS06450	COG2203	Gaf domain
AHALO_RS06465	COG2833	Protein of unknown function (DUF455)
AHALO_RS06470	COG0133	tryptophan synthase activity
AHALO_RS06480	COG0484	heat shock protein binding
AHALO_RS06490	COG0840	transmembrane signaling receptor activity
AHALO_RS06515	COG4191	Histidine kinase
AHALO_RS06520	COG0745	RESPONSE REGULATOR receiver
AHALO_RS06525	COG4753	response regulator
AHALO_RS06525	COG2207	Transcriptional regulator
AHALO_RS06555	COG0137	argininosuccinate synthase activity
AHALO_RS06565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AHALO_RS06575	COG1137	ATPase activity
AHALO_RS06580	COG3706	GGDEF domain
AHALO_RS06585	COG5001	Diguanylate cyclase
AHALO_RS06585	COG5002	protein histidine kinase activity
AHALO_RS06590	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AHALO_RS06600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AHALO_RS06600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AHALO_RS06620	COG0840	transmembrane signaling receptor activity
AHALO_RS06625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AHALO_RS06635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AHALO_RS06640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AHALO_RS06665	COG0189	ligase activity
AHALO_RS06685	COG0113	porphobilinogen synthase activity
AHALO_RS06690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AHALO_RS06695	COG0357	Ribosomal RNA small subunit methyltransferase G
AHALO_RS06765	COG0582	viral genome integration into host DNA
AHALO_RS06850	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AHALO_RS06855	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AHALO_RS06865	COG3630	sodium ion export across plasma membrane
AHALO_RS06880	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHALO_RS06880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHALO_RS06890	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AHALO_RS06915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHALO_RS06920	COG0612	Peptidase, M16
AHALO_RS06925	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AHALO_RS06930	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AHALO_RS06935	COG0287	Prephenate dehydrogenase
AHALO_RS06940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AHALO_RS06955	COG0527	aspartate kinase activity
AHALO_RS06960	COG0494	nUDIX hydrolase
AHALO_RS06965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AHALO_RS06970	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AHALO_RS06970	COG2890	protein-(glutamine-N5) methyltransferase activity
AHALO_RS06975	COG0339	signal peptide processing
AHALO_RS07065	COG0515	serine threonine protein kinase
AHALO_RS07100	COG0582	viral genome integration into host DNA
AHALO_RS07105	COG2201	protein-glutamate methylesterase activity
AHALO_RS07110	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AHALO_RS07115	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AHALO_RS07120	COG0643	Histidine kinase
AHALO_RS07120	COG2198	Histidine kinase
AHALO_RS07130	COG1185	polyribonucleotide nucleotidyltransferase activity
AHALO_RS07140	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AHALO_RS07160	COG1160	GTP binding
AHALO_RS07170	COG1196	nuclear chromosome segregation
AHALO_RS07170	COG1674	ftsk spoiiie
AHALO_RS07175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AHALO_RS07180	COG0440	acetolactate synthase activity
AHALO_RS07185	COG0028	Belongs to the TPP enzyme family
AHALO_RS07190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AHALO_RS07195	COG0248	Ppx GppA phosphatase
AHALO_RS07205	COG4251	negative regulation of phosphorylation
AHALO_RS07205	COG2203	Gaf domain
AHALO_RS07205	COG5001	Diguanylate cyclase
AHALO_RS07205	COG3706	GGDEF domain
AHALO_RS07220	COG3118	belongs to the thioredoxin family
AHALO_RS07235	COG0037	tRNA processing
AHALO_RS07240	COG2056	Na+-H+ antiporter family
AHALO_RS07250	COG0189	ligase activity
AHALO_RS07250	COG4067	protein conserved in archaea
AHALO_RS07265	COG1012	belongs to the aldehyde dehydrogenase family
AHALO_RS07270	COG0410	ABC transporter
AHALO_RS07310	COG0745	RESPONSE REGULATOR receiver
AHALO_RS07320	COG0303	'Molybdopterin
AHALO_RS07330	COG0477	Major facilitator Superfamily
AHALO_RS07335	COG1322	Protein conserved in bacteria
AHALO_RS07340	COG0501	Belongs to the peptidase M48B family
AHALO_RS07355	COG0824	Thioesterase
AHALO_RS07370	COG0667	Aldo Keto reductase
AHALO_RS07400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AHALO_RS07405	COG4206	TonB-dependent receptor
AHALO_RS07435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AHALO_RS07450	COG0546	phosphoglycolate phosphatase activity
AHALO_RS07460	COG0840	transmembrane signaling receptor activity
AHALO_RS07470	COG0848	biopolymer transport protein
AHALO_RS07475	COG0811	peptide transport
AHALO_RS07480	COG0642	Histidine kinase
AHALO_RS07485	COG0745	RESPONSE REGULATOR receiver
AHALO_RS07505	COG0788	formyltetrahydrofolate deformylase activity
AHALO_RS07510	COG0280	phosphate acetyltransferase
AHALO_RS07510	COG0281	malic enzyme
AHALO_RS07520	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AHALO_RS07545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AHALO_RS07545	COG0301	tRNA thio-modification
AHALO_RS07555	COG0754	glutathionylspermidine amidase activity
AHALO_RS07565	COG1663	tetraacyldisaccharide 4'-kinase activity
AHALO_RS07570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AHALO_RS07575	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AHALO_RS07595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AHALO_RS07600	COG0805	protein transport
AHALO_RS07605	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AHALO_RS07615	COG0733	neurotransmitter:sodium symporter activity
AHALO_RS07625	COG2199	diguanylate cyclase activity
AHALO_RS07645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AHALO_RS07655	COG4865	methylaspartate mutase activity
AHALO_RS07675	COG3706	GGDEF domain
AHALO_RS07705	COG0275	rRNA processing
AHALO_RS07715	COG0776	regulation of translation
AHALO_RS07725	COG2203	Gaf domain
AHALO_RS07725	COG3706	GGDEF domain
AHALO_RS07725	COG5001	Diguanylate cyclase
AHALO_RS07725	COG4251	negative regulation of phosphorylation
AHALO_RS07740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AHALO_RS07755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AHALO_RS07760	COG1917	Cupin 2, conserved barrel domain protein
AHALO_RS07775	COG0527	aspartate kinase activity
AHALO_RS07805	COG0642	Histidine kinase
AHALO_RS07810	COG0745	RESPONSE REGULATOR receiver
AHALO_RS07895	COG2201	protein-glutamate methylesterase activity
AHALO_RS07900	COG2200	EAL domain
AHALO_RS07900	COG3287	FIST C domain
AHALO_RS07900	COG2199	diguanylate cyclase activity
AHALO_RS07910	COG1132	(ABC) transporter
AHALO_RS07915	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AHALO_RS07935	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AHALO_RS07940	COG0653	protein targeting
AHALO_RS07970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AHALO_RS07970	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AHALO_RS07980	COG2201	protein-glutamate methylesterase activity
AHALO_RS07990	COG4191	Histidine kinase
AHALO_RS07995	COG0484	heat shock protein binding
AHALO_RS08000	COG0789	Transcriptional regulator
AHALO_RS08005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AHALO_RS08010	COG0849	cell division
AHALO_RS08020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AHALO_RS08030	COG1393	Belongs to the ArsC family
AHALO_RS08055	COG0768	penicillin binding
AHALO_RS08090	COG0456	acetyltransferase
AHALO_RS08095	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AHALO_RS08110	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AHALO_RS08115	COG0131	Imidazoleglycerol-phosphate dehydratase
AHALO_RS08120	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AHALO_RS08125	COG0860	N-Acetylmuramoyl-L-alanine amidase
AHALO_RS08125	COG1388	LysM domain
AHALO_RS08130	COG0084	hydrolase, TatD family'
AHALO_RS08140	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AHALO_RS08145	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AHALO_RS08150	COG0359	binds to the 23S rRNA
AHALO_RS08160	COG0163	prenyltransferase activity
AHALO_RS08165	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AHALO_RS08170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AHALO_RS08175	COG0124	histidyl-tRNA synthetase
AHALO_RS08180	COG1166	arginine decarboxylase activity
AHALO_RS08185	COG1045	serine acetyltransferase
AHALO_RS08190	COG0730	response to heat
AHALO_RS08195	COG4191	Histidine kinase
AHALO_RS08200	COG1473	amidohydrolase
AHALO_RS08205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AHALO_RS08210	COG1012	belongs to the aldehyde dehydrogenase family
AHALO_RS08215	COG0006	proline dipeptidase activity
AHALO_RS08220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AHALO_RS08230	COG1301	dicarboxylic acid transport
AHALO_RS08240	COG4536	flavin adenine dinucleotide binding
AHALO_RS08245	COG0748	coenzyme F420 binding
AHALO_RS08255	COG0259	pyridoxamine-phosphate oxidase activity
AHALO_RS08260	COG0386	Belongs to the glutathione peroxidase family
AHALO_RS08295	COG2011	ABC-type metal ion transport system permease component
AHALO_RS08300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AHALO_RS08305	COG1028	Short-chain dehydrogenase reductase Sdr
AHALO_RS08310	COG2223	nitrite transmembrane transporter activity
AHALO_RS08320	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AHALO_RS08325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AHALO_RS08330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AHALO_RS08345	COG0659	secondary active sulfate transmembrane transporter activity
AHALO_RS08355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHALO_RS08365	COG2264	protein methyltransferase activity
AHALO_RS08390	COG2133	pyrroloquinoline quinone binding
AHALO_RS08395	COG1643	Atp-dependent helicase
AHALO_RS08400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AHALO_RS08430	COG0582	viral genome integration into host DNA
AHALO_RS08520	COG0204	Acyl-transferase
AHALO_RS08525	COG0596	Alpha beta hydrolase
AHALO_RS08545	COG1278	Cold shock
AHALO_RS08590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AHALO_RS08590	COG0519	Catalyzes the synthesis of GMP from XMP
AHALO_RS08600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AHALO_RS08605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AHALO_RS08625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AHALO_RS08640	COG0840	transmembrane signaling receptor activity
AHALO_RS08645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AHALO_RS08655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHALO_RS08660	COG0508	dehydrogenase complex catalyzes the overall conversion of
AHALO_RS08665	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AHALO_RS08670	COG0095	Lipoate-protein ligase
AHALO_RS08675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AHALO_RS08680	COG0039	L-malate dehydrogenase activity
AHALO_RS08685	COG0488	(ABC) transporter
AHALO_RS08690	COG1610	YqeY-like protein
AHALO_RS08700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AHALO_RS08715	COG0300	oxidoreductase activity
AHALO_RS08720	COG1757	Na H antiporter
AHALO_RS08725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHALO_RS08730	COG0742	ribosomal rna small subunit methyltransferase
AHALO_RS08735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AHALO_RS08740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AHALO_RS08750	COG1418	mRNA catabolic process
AHALO_RS08760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AHALO_RS08765	COG0552	protein localization to endoplasmic reticulum
AHALO_RS08775	COG0745	RESPONSE REGULATOR receiver
AHALO_RS08780	COG5002	protein histidine kinase activity
AHALO_RS08785	COG3258	Cytochrome c
AHALO_RS08800	COG0840	transmembrane signaling receptor activity
AHALO_RS08805	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AHALO_RS08815	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AHALO_RS08820	COG0530	calcium, potassium:sodium antiporter activity
AHALO_RS08830	COG0783	Belongs to the Dps family
AHALO_RS08835	COG1592	Rubrerythrin
AHALO_RS08860	COG0728	peptidoglycan biosynthetic process
AHALO_RS08865	COG1132	(ABC) transporter
AHALO_RS08870	COG0167	dihydroorotate dehydrogenase activity
AHALO_RS08880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AHALO_RS08885	COG1028	Short-chain dehydrogenase reductase Sdr
AHALO_RS08890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AHALO_RS08895	COG0750	zinc metalloprotease
AHALO_RS08900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AHALO_RS08920	COG0189	ligase activity
AHALO_RS08925	COG0134	indole-3-glycerol-phosphate synthase activity
AHALO_RS08935	COG0727	PFAM Uncharacterised protein family (UPF0153)
AHALO_RS08940	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AHALO_RS08950	COG0674	pyruvate-flavodoxin oxidoreductase activity
AHALO_RS08950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AHALO_RS08955	COG0028	Belongs to the TPP enzyme family
AHALO_RS08975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AHALO_RS08980	COG2176	DNA-directed DNA polymerase activity
AHALO_RS08985	COG0135	phosphoribosylanthranilate isomerase activity
AHALO_RS08990	COG0745	RESPONSE REGULATOR receiver
AHALO_RS08995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AHALO_RS09000	COG3008	intermembrane lipid transfer
AHALO_RS09005	COG2995	paraquat-inducible protein a
AHALO_RS09010	COG2995	paraquat-inducible protein a
AHALO_RS09015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHALO_RS09035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AHALO_RS09045	COG0840	transmembrane signaling receptor activity
AHALO_RS09055	COG3177	Filamentation induced by cAMP protein fic
AHALO_RS09055	COG0666	response to abiotic stimulus
AHALO_RS09075	COG0642	Histidine kinase
AHALO_RS09080	COG0745	RESPONSE REGULATOR receiver
AHALO_RS09090	COG0583	DNA-binding transcription factor activity
AHALO_RS09100	COG1666	GTP binding
AHALO_RS09115	COG2233	PERMEase
AHALO_RS09120	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AHALO_RS09130	COG2363	Small membrane protein
AHALO_RS09140	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AHALO_RS09145	COG2252	PERMEase
AHALO_RS09155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AHALO_RS09160	COG4977	sequence-specific DNA binding
AHALO_RS09165	COG3437	response regulator, receiver
AHALO_RS09165	COG0784	Response regulator, receiver
AHALO_RS09175	COG0640	Transcriptional regulator
AHALO_RS09180	COG2217	Heavy metal translocating P-type atpase
AHALO_RS09195	COG0747	negative chemotaxis
AHALO_RS09200	COG0745	RESPONSE REGULATOR receiver
AHALO_RS09210	COG0243	molybdopterin cofactor binding
AHALO_RS09215	COG1979	alcohol dehydrogenase
AHALO_RS09230	COG1918	ferrous iron import across plasma membrane
AHALO_RS09235	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AHALO_RS09235	COG1918	ferrous iron import across plasma membrane
AHALO_RS09275	COG0731	radical SAM domain protein
AHALO_RS09280	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AHALO_RS09290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AHALO_RS09305	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AHALO_RS09315	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AHALO_RS09325	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AHALO_RS09330	COG0859	PFAM glycosyl transferase family 9
AHALO_RS09345	COG0859	PFAM glycosyl transferase family 9
AHALO_RS09355	COG0515	serine threonine protein kinase
AHALO_RS09360	COG0297	glycogen (starch) synthase activity
AHALO_RS09365	COG0463	Glycosyl transferase, family 2
AHALO_RS09410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AHALO_RS09420	COG0859	PFAM glycosyl transferase family 9
AHALO_RS09440	COG0493	'glutamate synthase
AHALO_RS09445	COG0070	glutamate synthase
AHALO_RS09445	COG0069	glutamate synthase activity
AHALO_RS09445	COG0067	glutamate synthase
AHALO_RS09485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AHALO_RS09500	COG1942	4-Oxalocrotonate Tautomerase
AHALO_RS09510	COG0583	DNA-binding transcription factor activity
AHALO_RS09545	COG0745	RESPONSE REGULATOR receiver
AHALO_RS09555	COG0419	ATPase involved in DNA repair
AHALO_RS09645	COG0284	orotidine-5'-phosphate decarboxylase activity
AHALO_RS09650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AHALO_RS09655	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AHALO_RS09675	COG0069	glutamate synthase activity
AHALO_RS09685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AHALO_RS09705	COG1739	Uncharacterized protein family UPF0029
AHALO_RS09720	COG2226	methyltransferase
AHALO_RS09725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AHALO_RS09735	COG0277	FAD linked oxidase domain protein
AHALO_RS09745	COG2203	Gaf domain
AHALO_RS09745	COG3706	GGDEF domain
AHALO_RS09745	COG4251	negative regulation of phosphorylation
AHALO_RS09745	COG5001	Diguanylate cyclase
AHALO_RS09780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AHALO_RS09785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AHALO_RS09790	COG1047	Peptidyl-prolyl cis-trans
AHALO_RS09805	COG0823	Involved in the tonB-independent uptake of proteins
AHALO_RS09815	COG0848	biopolymer transport protein
AHALO_RS09820	COG0811	peptide transport
AHALO_RS09825	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AHALO_RS09830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AHALO_RS09835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AHALO_RS09840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AHALO_RS09845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AHALO_RS09850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AHALO_RS09860	COG1475	DNA binding
AHALO_RS09865	COG1192	Involved in chromosome partitioning
AHALO_RS09885	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AHALO_RS09890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AHALO_RS09895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AHALO_RS09900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AHALO_RS09905	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AHALO_RS09910	COG0251	oxidation-reduction process
AHALO_RS09915	COG0358	DNA primase activity
AHALO_RS09925	COG0328	RNA-DNA hybrid ribonuclease activity
AHALO_RS09930	COG0571	ribonuclease III activity
AHALO_RS09935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AHALO_RS09945	COG1342	Belongs to the UPF0251 family
AHALO_RS09950	COG0501	Belongs to the peptidase M48B family
AHALO_RS09965	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AHALO_RS09975	COG0706	membrane insertase activity
AHALO_RS09980	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AHALO_RS09985	COG0594	ribonuclease P activity
AHALO_RS09990	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AHALO_RS10000	COG0542	response to heat
AHALO_RS10020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AHALO_RS10030	COG5001	Diguanylate cyclase
AHALO_RS10030	COG5002	protein histidine kinase activity
AHALO_RS10040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHALO_RS10040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHALO_RS10045	COG0179	Fumarylacetoacetate (FAA) hydrolase
AHALO_RS10055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AHALO_RS10070	COG2610	gluconate transmembrane transporter activity
AHALO_RS10075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AHALO_RS10110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AHALO_RS10120	COG0741	lytic transglycosylase activity
AHALO_RS10120	COG1196	nuclear chromosome segregation
AHALO_RS10120	COG0739	heme binding
AHALO_RS10125	COG2239	Acts as a magnesium transporter
AHALO_RS10135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AHALO_RS10150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AHALO_RS10165	COG0415	Belongs to the DNA photolyase family
AHALO_RS10185	COG0351	phosphomethylpyrimidine kinase
AHALO_RS10190	COG3279	Response regulator of the LytR AlgR family
AHALO_RS10195	COG3275	phosphorelay sensor kinase activity
AHALO_RS10205	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AHALO_RS10210	COG2989	Protein conserved in bacteria
AHALO_RS10220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AHALO_RS10225	COG0606	chelatase, subunit chli
AHALO_RS10240	COG0242	peptide deformylase activity
AHALO_RS10245	COG0740	serine-type endopeptidase activity
AHALO_RS10250	COG0544	peptidyl-prolyl cis-trans isomerase activity
AHALO_RS10270	COG2326	polyphosphate kinase activity
AHALO_RS10285	COG1773	rubredoxin
AHALO_RS10300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AHALO_RS10320	COG0840	transmembrane signaling receptor activity
AHALO_RS10330	COG0668	transmembrane transport
AHALO_RS10345	COG1271	oxidase subunit
AHALO_RS10355	COG1342	Belongs to the UPF0251 family
AHALO_RS10380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AHALO_RS10395	COG4771	TonB-dependent receptor
AHALO_RS10420	COG0716	FMN binding
AHALO_RS10425	COG0716	FMN binding
AHALO_RS10430	COG0716	FMN binding
AHALO_RS10485	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AHALO_RS10510	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AHALO_RS10515	COG0159	tryptophan synthase activity
AHALO_RS10520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AHALO_RS10525	COG2255	four-way junction helicase activity
AHALO_RS10530	COG0628	permease
AHALO_RS10550	COG1518	maintenance of DNA repeat elements
AHALO_RS10555	COG1373	ATPase (AAA superfamily
AHALO_RS10590	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AHALO_RS10595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AHALO_RS10595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AHALO_RS10605	COG0542	response to heat
AHALO_RS10610	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AHALO_RS10615	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AHALO_RS10645	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AHALO_RS10655	COG1157	protein secretion by the type III secretion system
AHALO_RS10665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AHALO_RS10685	COG1677	Flagellar hook-basal body complex protein FliE
AHALO_RS10695	COG0455	bacterial-type flagellum organization
AHALO_RS10700	COG1419	protein localization to endoplasmic reticulum
AHALO_RS10715	COG3951	Flagellar rod assembly protein muramidase FlgJ
AHALO_RS10725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AHALO_RS10730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AHALO_RS10730	COG1776	CheC inhibitor of MCP methylation
AHALO_RS10750	COG1749	Flagellar hook protein flgE
AHALO_RS10755	COG1749	Flagellar hook protein flgE
AHALO_RS10765	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AHALO_RS10775	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AHALO_RS10780	COG1766	The M ring may be actively involved in energy transduction
AHALO_RS10785	COG1815	bacterial-type flagellum-dependent cell motility
AHALO_RS10790	COG4786	Flagellar basal body rod
AHALO_RS10800	COG0745	RESPONSE REGULATOR receiver
AHALO_RS10820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AHALO_RS10830	COG0228	four-way junction DNA binding
AHALO_RS10835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AHALO_RS10840	COG0564	pseudouridine synthase activity
AHALO_RS10845	COG1519	Transferase
AHALO_RS10845	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AHALO_RS10855	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AHALO_RS10860	COG0752	glycyl-tRNA synthetase alpha subunit
AHALO_RS10875	COG0826	peptidase U32
AHALO_RS10880	COG0840	transmembrane signaling receptor activity
AHALO_RS10880	COG0840	transmembrane signaling receptor activity
AHALO_RS10890	COG0497	DNA recombination
AHALO_RS10895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AHALO_RS10900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AHALO_RS10905	COG0049	tRNA binding
AHALO_RS10910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AHALO_RS10915	COG2814	Major facilitator Superfamily
AHALO_RS10930	COG1671	Belongs to the UPF0178 family
AHALO_RS10935	COG4895	conserved protein (DUF2196)
AHALO_RS10990	COG0745	RESPONSE REGULATOR receiver
AHALO_RS11005	COG2860	membrane
AHALO_RS11050	COG0582	viral genome integration into host DNA
AHALO_RS11070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AHALO_RS11075	COG0085	RNA polymerase activity
AHALO_RS11080	COG0222	ribosome binding
AHALO_RS11085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AHALO_RS11090	COG0081	regulation of translation
AHALO_RS11095	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AHALO_RS11100	COG0250	Participates in transcription elongation, termination and antitermination
AHALO_RS11115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AHALO_RS11120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AHALO_RS11145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AHALO_RS11150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AHALO_RS11155	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AHALO_RS11165	COG0444	Belongs to the ABC transporter superfamily
AHALO_RS11170	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AHALO_RS11175	COG0174	glutamine synthetase
AHALO_RS11180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AHALO_RS11185	COG3706	GGDEF domain
AHALO_RS11190	COG0314	molybdopterin synthase activity
AHALO_RS11200	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AHALO_RS11205	COG1968	undecaprenyl-diphosphatase activity
AHALO_RS11215	COG0772	Belongs to the SEDS family
AHALO_RS11220	COG0768	penicillin binding
AHALO_RS11225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AHALO_RS11375	COG1840	ABC-type Fe3 transport system, periplasmic component
AHALO_RS11385	COG3842	ATPase activity
AHALO_RS11390	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AHALO_RS11395	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AHALO_RS11400	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHALO_RS11405	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHALO_RS11410	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHALO_RS11410	COG0649	NAD binding
AHALO_RS11415	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AHALO_RS11425	COG0372	Belongs to the citrate synthase family
AHALO_RS11435	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AHALO_RS11440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHALO_RS11445	COG0839	Belongs to the complex I subunit 6 family
AHALO_RS11450	COG0713	ATP synthesis coupled electron transport
AHALO_RS11455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AHALO_RS11465	COG1007	ATP synthesis coupled electron transport
AHALO_RS11475	COG1053	succinate dehydrogenase
AHALO_RS11480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AHALO_RS11490	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AHALO_RS11495	COG1929	Belongs to the glycerate kinase type-1 family
AHALO_RS11510	COG0038	chloride channel
AHALO_RS11525	COG1012	belongs to the aldehyde dehydrogenase family
AHALO_RS11535	COG0045	succinate-CoA ligase (ADP-forming) activity
AHALO_RS11565	COG2095	MarC family integral membrane protein
AHALO_RS11570	COG0765	amino acid transport
AHALO_RS11590	COG0500	methyltransferase
AHALO_RS11600	COG1335	isochorismatase
AHALO_RS11610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AHALO_RS11615	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AHALO_RS11620	COG0514	ATP-dependent DNA helicase (RecQ)
AHALO_RS11635	COG1280	lysine exporter protein (LysE YggA)
AHALO_RS11645	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AHALO_RS11650	COG0372	Belongs to the citrate synthase family
AHALO_RS11655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AHALO_RS11670	COG0181	hydroxymethylbilane synthase activity
AHALO_RS11685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AHALO_RS11700	COG0784	Response regulator, receiver
AHALO_RS11705	COG4774	siderophore transport
AHALO_RS11705	COG1629	transport
AHALO_RS11710	COG2382	esterase
AHALO_RS11715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AHALO_RS11720	COG0450	alkyl hydroperoxide reductase
AHALO_RS11725	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AHALO_RS11735	COG0105	UTP biosynthetic process
AHALO_RS11745	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AHALO_RS11750	COG0416	fatty acid biosynthetic process
AHALO_RS11755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AHALO_RS11765	COG1687	branched-chain amino acid
AHALO_RS11770	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AHALO_RS11805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AHALO_RS11815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AHALO_RS11835	COG1012	belongs to the aldehyde dehydrogenase family
AHALO_RS11840	COG0642	Histidine kinase
AHALO_RS11845	COG0745	RESPONSE REGULATOR receiver
AHALO_RS11850	COG2104	thiamine diphosphate biosynthetic process
AHALO_RS11855	COG0792	nuclease activity
AHALO_RS11865	COG0840	transmembrane signaling receptor activity
AHALO_RS11870	COG0156	8-amino-7-oxononanoate synthase activity
AHALO_RS11880	COG0288	reversible hydration of carbon dioxide
AHALO_RS11890	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AHALO_RS11900	COG2121	Domain of unknown function (DUF374)
AHALO_RS11905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AHALO_RS11915	COG0195	Participates in both transcription termination and antitermination
AHALO_RS11920	COG0215	cysteine-tRNA ligase activity
AHALO_RS11925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AHALO_RS11930	COG0629	single-stranded DNA binding
AHALO_RS11935	COG0360	Binds together with S18 to 16S ribosomal RNA
AHALO_RS11940	COG1466	dna polymerase III delta subunit
AHALO_RS11945	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AHALO_RS11950	COG0557	exoribonuclease II activity
AHALO_RS11965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AHALO_RS11980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AHALO_RS11990	COG5002	protein histidine kinase activity
AHALO_RS11995	COG0745	RESPONSE REGULATOR receiver
AHALO_RS12000	COG3301	Polysulphide reductase, NrfD
AHALO_RS12005	COG0437	4 iron, 4 sulfur cluster binding
AHALO_RS12015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AHALO_RS12030	COG0436	Aminotransferase
AHALO_RS12040	COG0343	queuine tRNA-ribosyltransferase activity
AHALO_RS12045	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AHALO_RS12050	COG1393	Belongs to the ArsC family
AHALO_RS12055	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AHALO_RS12060	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AHALO_RS12065	COG0560	Phosphoserine phosphatase
AHALO_RS12070	COG0646	methionine synthase
AHALO_RS12070	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AHALO_RS12075	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AHALO_RS12080	COG0736	holo-[acyl-carrier-protein] synthase activity
AHALO_RS12085	COG0601	transmembrane transport
AHALO_RS12090	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AHALO_RS12095	COG0745	RESPONSE REGULATOR receiver
AHALO_RS12100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AHALO_RS12120	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AHALO_RS12125	COG4786	Flagellar basal body rod
AHALO_RS12125	COG1256	bacterial-type flagellum assembly
AHALO_RS12165	COG1706	bacterial-type flagellum-dependent cell motility
AHALO_RS12170	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AHALO_RS12180	COG0004	ammonium transporteR
AHALO_RS12190	COG0004	ammonium transporteR
AHALO_RS12215	COG0659	secondary active sulfate transmembrane transporter activity
AHALO_RS12225	COG2962	Rard protein
AHALO_RS12240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AHALO_RS12245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AHALO_RS12260	COG1253	flavin adenine dinucleotide binding
AHALO_RS12265	COG1346	cytolysis
AHALO_RS12270	COG1380	Effector of murein hydrolase LrgA
AHALO_RS12280	COG0745	RESPONSE REGULATOR receiver
AHALO_RS12285	COG5000	phosphorelay sensor kinase activity
AHALO_RS12290	COG0252	asparaginase activity
AHALO_RS12295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AHALO_RS12300	COG1027	Aspartate ammonia-lyase
AHALO_RS12305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AHALO_RS12310	COG1053	succinate dehydrogenase
AHALO_RS12320	COG5000	phosphorelay sensor kinase activity
AHALO_RS12325	COG0540	Belongs to the ATCase OTCase family
AHALO_RS12330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AHALO_RS12335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AHALO_RS12340	COG3069	C4-dicarboxylate transmembrane transporter activity
AHALO_RS12345	COG1473	amidohydrolase
AHALO_RS12350	COG3069	C4-dicarboxylate transmembrane transporter activity
AHALO_RS12355	COG1027	Aspartate ammonia-lyase
AHALO_RS12360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AHALO_RS12390	COG2274	protein secretion by the type I secretion system
AHALO_RS12400	COG0745	RESPONSE REGULATOR receiver
AHALO_RS12405	COG0628	permease
AHALO_RS12415	COG4191	Histidine kinase
AHALO_RS12440	COG2207	Transcriptional regulator
AHALO_RS12470	COG0129	dihydroxy-acid dehydratase activity
AHALO_RS12475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AHALO_RS12480	COG0745	RESPONSE REGULATOR receiver
AHALO_RS12485	COG0642	Histidine kinase
AHALO_RS12500	COG1492	cobalamin metabolic process
AHALO_RS12510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AHALO_RS12515	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AHALO_RS12525	COG2095	MarC family integral membrane protein
AHALO_RS12530	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AHALO_RS12535	COG0745	RESPONSE REGULATOR receiver
AHALO_RS12540	COG4191	Histidine kinase
AHALO_RS12580	COG0688	phosphatidylethanolamine metabolic process
AHALO_RS12590	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AHALO_RS12595	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AHALO_RS12605	COG0443	Heat shock 70 kDa protein
AHALO_RS12610	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AHALO_RS12615	COG1420	regulation of RNA biosynthetic process
AHALO_RS12630	COG4191	Histidine kinase
AHALO_RS12640	COG2358	TRAP transporter, solute receptor (TAXI family
AHALO_RS12665	COG0101	tRNA pseudouridine synthase activity
AHALO_RS12675	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AHALO_RS12680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AHALO_RS12685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AHALO_RS12690	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AHALO_RS12705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AHALO_RS12740	COG2089	acid synthase
AHALO_RS12750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AHALO_RS12760	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AHALO_RS12800	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AHALO_RS12815	COG0529	Catalyzes the synthesis of activated sulfate
AHALO_RS12825	COG2046	Belongs to the sulfate adenylyltransferase family
AHALO_RS12840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AHALO_RS12845	COG3959	Transketolase, thiamine diphosphate binding domain
AHALO_RS12850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AHALO_RS12865	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AHALO_RS12865	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AHALO_RS12870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AHALO_RS12875	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AHALO_RS12880	COG0148	phosphopyruvate hydratase activity
AHALO_RS12895	COG0569	domain protein
AHALO_RS12895	COG0475	glutathione-regulated potassium exporter activity
AHALO_RS12900	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AHALO_RS12920	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AHALO_RS12930	COG1007	ATP synthesis coupled electron transport
AHALO_RS12940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AHALO_RS12945	COG0713	ATP synthesis coupled electron transport
AHALO_RS12950	COG0839	Belongs to the complex I subunit 6 family
AHALO_RS12955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHALO_RS12960	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AHALO_RS12980	COG0649	NAD binding
AHALO_RS12990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHALO_RS12995	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHALO_RS13000	COG1222	aaa ATPase
AHALO_RS13020	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AHALO_RS13025	COG1252	NADH dehydrogenase
AHALO_RS13055	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AHALO_RS13060	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AHALO_RS13065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AHALO_RS13070	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AHALO_RS13075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AHALO_RS13080	COG1077	Cell shape determining protein MreB Mrl
AHALO_RS13105	COG0840	transmembrane signaling receptor activity
AHALO_RS13110	COG0445	tRNA wobble uridine modification
AHALO_RS13130	COG1960	acyl-CoA dehydrogenase activity
AHALO_RS13135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AHALO_RS13145	COG2030	dehydratase
AHALO_RS13155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AHALO_RS13175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AHALO_RS13180	COG2030	dehydratase
AHALO_RS13195	COG0644	oxidoreductase
AHALO_RS13200	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AHALO_RS13210	COG0348	domain, Protein
AHALO_RS13215	COG0504	CTP synthase activity
AHALO_RS13220	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AHALO_RS13220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AHALO_RS13250	COG0587	DNA-directed DNA polymerase activity
AHALO_RS13255	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AHALO_RS13280	COG0315	cyclic pyranopterin monophosphate synthase activity
AHALO_RS13285	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AHALO_RS13290	COG0471	metal ion transport
AHALO_RS13320	COG0670	Belongs to the BI1 family
AHALO_RS13325	COG0352	thiamine-phosphate diphosphorylase activity
AHALO_RS13335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AHALO_RS13345	COG0233	cytoplasmic translational termination
AHALO_RS13350	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AHALO_RS13360	COG2814	Major facilitator Superfamily
AHALO_RS13365	COG3022	response to hydroperoxide
AHALO_RS13370	COG3012	SEC-C Motif Domain Protein
AHALO_RS13390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AHALO_RS13395	COG1704	LemA family
AHALO_RS13410	COG0546	phosphoglycolate phosphatase activity
AHALO_RS13435	COG0415	Belongs to the DNA photolyase family
AHALO_RS13440	COG2081	HI0933 family
AHALO_RS13455	COG1959	2 iron, 2 sulfur cluster binding
AHALO_RS13470	COG0175	sulfate reduction
AHALO_RS13475	COG0175	sulfate reduction
AHALO_RS13480	COG2895	sulfate adenylyltransferase (ATP) activity
AHALO_RS13490	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AHALO_RS13495	COG0840	transmembrane signaling receptor activity
AHALO_RS13500	COG1408	metallophosphoesterase
AHALO_RS13515	COG1217	gtp-binding protein TYPA
AHALO_RS13525	COG0577	efflux transmembrane transporter activity
AHALO_RS13525	COG1136	(ABC) transporter
AHALO_RS13550	COG1408	metallophosphoesterase
AHALO_RS13555	COG0745	RESPONSE REGULATOR receiver
AHALO_RS13560	COG5002	protein histidine kinase activity
AHALO_RS13565	COG2391	methyltransferase activity
AHALO_RS13570	COG0425	Belongs to the sulfur carrier protein TusA family
AHALO_RS13575	COG2066	Belongs to the glutaminase family
AHALO_RS13605	COG0745	RESPONSE REGULATOR receiver
AHALO_RS13610	COG0642	Histidine kinase
AHALO_RS13615	COG2860	membrane
AHALO_RS13620	COG0840	transmembrane signaling receptor activity
AHALO_RS13625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AHALO_RS13630	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group