locus-tag	class	description
ALEK_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ALEK_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
ALEK_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ALEK_RS00030	ENOG4105CAY	ferredoxin--nadp reductase
ALEK_RS00035	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
ALEK_RS00060	ENOG4105EI2	Pseudouridine synthase
ALEK_RS00065	ENOG4107QTF	adenylosuccinate lyase
ALEK_RS00070	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ALEK_RS00075	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ALEK_RS00095	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
ALEK_RS00135	ENOG4105BZ8	glutamate synthase
ALEK_RS00140	ENOG4105UYK	outer membrane protein a
ALEK_RS00170	ENOG4107QKV	phosphomannomutase
ALEK_RS00175	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ALEK_RS00190	ENOG4107VQW	regulatoR
ALEK_RS00195	ENOG4105BZU	Histidine kinase
ALEK_RS00205	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ALEK_RS00210	ENOG4105N14	lysine exporter protein LysE YggA
ALEK_RS00230	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
ALEK_RS00240	ENOG4105KVH	Transcriptional regulator
ALEK_RS00265	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ALEK_RS00270	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ALEK_RS00275	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
ALEK_RS00285	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_RS00295	ENOG4105CH5	extracellular solute-binding protein, family 7
ALEK_RS00305	ENOG4108F01	MaoC domain protein
ALEK_RS00315	ENOG4105C1G	acyl-Coa dehydrogenase
ALEK_RS00320	ENOG4105DF6	Fe-S oxidoreductase
ALEK_RS00325	ENOG4105BZJ	Electron transfer flavoprotein
ALEK_RS00330	ENOG4105C10	Electron transfer flavoprotein
ALEK_RS00335	ENOG4105FQ6	thiopurine methyltransferase
ALEK_RS00340	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ALEK_RS00345	ENOG4105KA0	thioesterase Superfamily protein
ALEK_RS00350	ENOG4107YD3	Thioesterase
ALEK_RS00355	ENOG4107QP7	CoA-transferase subunit A
ALEK_RS00365	ENOG4105CHU	acetyl-coa acetyltransferase
ALEK_RS00370	ENOG4105BZU	Histidine kinase
ALEK_RS00380	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS00385	ENOG4105BZU	Histidine kinase
ALEK_RS00390	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
ALEK_RS00395	ENOG4107QR9	Iron-sulfur cluster binding protein
ALEK_RS00400	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
ALEK_RS00410	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ALEK_RS00415	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ALEK_RS00420	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ALEK_RS00425	ENOG4105C1J	atp-dependent rna helicase
ALEK_RS00435	ENOG4105CJ3	phosphate transporter
ALEK_RS00440	ENOG4108PYU	two-component system response regulator
ALEK_RS00450	ENOG4105CAQ	asparagine synthetase
ALEK_RS00460	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
ALEK_RS00465	ENOG4105CH5	extracellular solute-binding protein, family 7
ALEK_RS00475	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
ALEK_RS00485	ENOG4108IAB	Phoh family
ALEK_RS00490	ENOG4108YXA	Membrane
ALEK_RS00495	ENOG4105D1H	recombination factor protein RarA
ALEK_RS00500	ENOG4105FE9	pseudouridine synthase
ALEK_RS00505	ENOG4105C2X	Arabinose 5-phosphate isomerase
ALEK_RS00515	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ALEK_RS00520	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ALEK_RS00535	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ALEK_RS00540	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ALEK_RS00545	ENOG4105VFU	Rna-binding protein
ALEK_RS00550	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS00580	ENOG4108IJF	Heavy metal efflux pump, CzcA
ALEK_RS00590	ENOG4105E18	UPF0276 protein
ALEK_RS00605	ENOG4105D6E	homoserine dehydrogenase
ALEK_RS00610	ENOG4105CHM	Aminotransferase
ALEK_RS00630	ENOG41082DI	50s ribosomal protein l31
ALEK_RS00635	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
ALEK_RS00650	ENOG41064RH	membrane protein YliF
ALEK_RS00665	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS00670	ENOG4105BZU	Histidine kinase
ALEK_RS00675	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
ALEK_RS00685	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
ALEK_RS00690	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
ALEK_RS00695	ENOG41084QV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
ALEK_RS00700	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
ALEK_RS00705	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS00710	ENOG4105C2C	drug resistance transporter, Bcr CflA
ALEK_RS00715	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ALEK_RS00720	ENOG4105C2I	pirin domain protein
ALEK_RS00730	ENOG4108YYH	Nadph-dependent fmn reductase
ALEK_RS00735	ENOG4108YYC	ycei family
ALEK_RS00745	ENOG410829K	Lysine exporter protein (Lyse ygga)
ALEK_RS00750	ENOG4107UUH	Aminotransferase
ALEK_RS00755	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
ALEK_RS00760	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ALEK_RS00770	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
ALEK_RS00780	ENOG4105KVH	Transcriptional regulator
ALEK_RS00795	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
ALEK_RS00805	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
ALEK_RS00820	ENOG4105D1F	ATP-binding protein
ALEK_RS00825	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
ALEK_RS00840	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ALEK_RS00855	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ALEK_RS00870	ENOG4105MSB	protein, conserved in bacteria
ALEK_RS00880	ENOG4105DIK	(ABC) transporter
ALEK_RS00915	ENOG410624X	efflux transporter, rnd family, mfp subunit
ALEK_RS00930	ENOG4105YIC	Major outer membrane protein
ALEK_RS00935	ENOG4108I6A	alcohol dehydrogenase
ALEK_RS00940	ENOG4105CF7	AraC family transcriptional regulator
ALEK_RS00945	ENOG4108I6A	alcohol dehydrogenase
ALEK_RS00950	ENOG4105CF7	AraC family transcriptional regulator
ALEK_RS00955	ENOG4107QY8	reductase
ALEK_RS00965	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS00990	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
ALEK_RS01020	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
ALEK_RS01030	ENOG4105CXC	rtn protein
ALEK_RS01035	ENOG4108KK1	membrane protein AbrB duplication
ALEK_RS01045	ENOG4107B2H	carbonic anhydrase
ALEK_RS01055	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS01075	ENOG4105KVH	Transcriptional regulator
ALEK_RS01080	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
ALEK_RS01085	ENOG4105DDK	oxidoreductase, beta subunit
ALEK_RS01090	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
ALEK_RS01100	ENOG4105EJ5	oxidoreductase gamma subunit
ALEK_RS01105	ENOG4107XGZ	Hydrolase
ALEK_RS01115	ENOG4108UJD	30S ribosomal protein S9
ALEK_RS01120	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
ALEK_RS01125	ENOG4105BZU	Histidine kinase
ALEK_RS01130	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS01140	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
ALEK_RS01145	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
ALEK_RS01150	ENOG4105E2Z	phosphate ABC transporter (Permease
ALEK_RS01155	ENOG4105C8U	phosphate abc transporter
ALEK_RS01160	ENOG4108M8H	domain protein
ALEK_RS01175	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ALEK_RS01180	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
ALEK_RS01185	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
ALEK_RS01190	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ALEK_RS01195	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ALEK_RS01215	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ALEK_RS01220	ENOG41084M8	50s ribosomal protein L35
ALEK_RS01225	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ALEK_RS01270	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ALEK_RS01290	ENOG4105C0W	non-ribosomal peptide synthetase
ALEK_RS01305	ENOG4105CJ1	ABC, transporter
ALEK_RS01330	ENOG4105CHR	reductase
ALEK_RS01335	ENOG4105C84	Histidine ammonia-lyase
ALEK_RS01355	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ALEK_RS01360	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ALEK_RS01385	ENOG4105KNE	Phosphatidate cytidylyltransferase
ALEK_RS01390	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
ALEK_RS01410	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ALEK_RS01415	ENOG4108ZJT	translation initiation factor, Sui1
ALEK_RS01420	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
ALEK_RS01425	ENOG4105VF7	tolerance protein
ALEK_RS01430	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ALEK_RS01525	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ALEK_RS01555	ENOG4105CN1	protease
ALEK_RS01560	ENOG4105C8V	SAICAR synthetase
ALEK_RS01565	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
ALEK_RS01570	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
ALEK_RS01580	ENOG4105E9Q	Acyl-transferase
ALEK_RS01585	ENOG4105WMR	Protein CrcB homolog
ALEK_RS01590	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ALEK_RS01595	ENOG4105C75	arginyL-tRNA synthetase
ALEK_RS01605	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
ALEK_RS01615	ENOG4105BZA	Phosphoglycerate kinase
ALEK_RS01620	ENOG4105CP7	Triose-phosphate isomerase
ALEK_RS01625	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
ALEK_RS01630	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ALEK_RS01635	ENOG4105CQC	Prephenate dehydratase
ALEK_RS01640	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ALEK_RS01645	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ALEK_RS01655	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
ALEK_RS01680	ENOG4105C26	Dehydrogenase
ALEK_RS01700	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
ALEK_RS01715	ENOG4105G3Z	GntR family transcriptional regulator
ALEK_RS01720	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
ALEK_RS01730	ENOG4108K1J	Transporter DctQ
ALEK_RS01735	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_RS01740	ENOG4107RCH	Diaminopropionate ammonia-lyase
ALEK_RS01745	ENOG4107S4Y	M20 DapE family protein YgeY
ALEK_RS01760	ENOG4105C5W	Aldolase
ALEK_RS01775	ENOG4107YJQ	MAF-like protein
ALEK_RS01790	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
ALEK_RS01795	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
ALEK_RS01825	ENOG4105DHT	Metal Dependent Phosphohydrolase
ALEK_RS01840	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_RS01880	ENOG4105HF0	Membrane
ALEK_RS01910	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
ALEK_RS01915	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
ALEK_RS01930	ENOG4105DEN	Luciferase family
ALEK_RS01935	ENOG4108JNI	Alpha beta hydrolase
ALEK_RS01955	ENOG4107TT5	NLP P60 protein
ALEK_RS01960	ENOG4107TT5	NLP P60 protein
ALEK_RS01980	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ALEK_RS01985	ENOG4105K63	Thioredoxin
ALEK_RS01990	ENOG4105K63	Thioredoxin
ALEK_RS02000	ENOG4105BZU	Histidine kinase
ALEK_RS02005	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_RS02010	ENOG4105BZG	amino acid carrier protein
ALEK_RS02015	ENOG4105C3M	thioredoxin reductase
ALEK_RS02020	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
ALEK_RS02025	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
ALEK_RS02030	ENOG4105N5T	Radical SAM Protein
ALEK_RS02035	ENOG4105DUM	transcriptional regulator, lysR family
ALEK_RS02040	ENOG4105C4R	Atp-dependent dna helicase
ALEK_RS02045	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ALEK_RS02050	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
ALEK_RS02055	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
ALEK_RS02060	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
ALEK_RS02100	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
ALEK_RS02120	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
ALEK_RS02130	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ALEK_RS02145	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALEK_RS02155	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
ALEK_RS02165	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ALEK_RS02170	ENOG4105MGB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
ALEK_RS02175	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
ALEK_RS02185	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
ALEK_RS02190	ENOG4108JQ1	Dehydrogenase
ALEK_RS02195	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ALEK_RS02200	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
ALEK_RS02205	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ALEK_RS02210	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ALEK_RS02215	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ALEK_RS02220	ENOG4105K59	histidine triad (HIT) protein
ALEK_RS02225	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
ALEK_RS02230	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ALEK_RS02235	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ALEK_RS02240	ENOG4105CHR	reductase
ALEK_RS02245	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
ALEK_RS02255	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
ALEK_RS02260	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ALEK_RS02270	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
ALEK_RS02285	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ALEK_RS02290	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ALEK_RS02295	ENOG4107QID	Threonine synthase
ALEK_RS02300	ENOG4105CAS	nag kinase
ALEK_RS02305	ENOG4105BZU	Histidine kinase
ALEK_RS02310	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
ALEK_RS02320	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
ALEK_RS02325	ENOG4105C7B	Threonine dehydratase
ALEK_RS02330	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
ALEK_RS02335	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
ALEK_RS02345	ENOG4107T5V	SNARE associated Golgi
ALEK_RS02355	ENOG4105DKW	ABC transporter
ALEK_RS02365	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ALEK_RS02375	ENOG4105CIF	Ornithine Cyclodeaminase
ALEK_RS02380	ENOG4105CTU	Proline racemase
ALEK_RS02385	ENOG4105F4E	fad dependent oxidoreductase
ALEK_RS02390	ENOG4108HW3	(ABC) transporter
ALEK_RS02395	ENOG4105DSP	amino acid AbC transporter
ALEK_RS02400	ENOG4105E5Q	amino acid AbC transporter
ALEK_RS02405	ENOG4105CDA	abc transporter atp-binding protein
ALEK_RS02410	ENOG4107WEA	mandelate racemase muconate lactonizing
ALEK_RS02420	ENOG4105CTU	Proline racemase
ALEK_RS02450	ENOG4105C32	Amino acid ABC transporter (Permease)
ALEK_RS02455	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
ALEK_RS02460	ENOG4105C0Z	ABC transporter
ALEK_RS02465	ENOG4108IV0	ABC, transporter
ALEK_RS02470	ENOG4105C26	Dehydrogenase
ALEK_RS02480	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS02520	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
ALEK_RS02540	ENOG4105KCK	Peptidoglycan-associated lipoprotein
ALEK_RS02550	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ALEK_RS02575	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
ALEK_RS02580	ENOG4105WH1	Two component transcriptional regulator luxr family
ALEK_RS02600	ENOG4107QYG	anthranilate phosphoribosyltransferase
ALEK_RS02625	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ALEK_RS02635	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
ALEK_RS02675	ENOG4108VKQ	nitriC oxide reductase
ALEK_RS02685	ENOG4107VQW	regulatoR
ALEK_RS02700	ENOG4105CNM	Receptor
ALEK_RS02705	ENOG4105BZU	Histidine kinase
ALEK_RS02750	ENOG4105CE1	Ferrous iron transport protein b
ALEK_RS02765	ENOG410822N	TonB family
ALEK_RS02770	ENOG4109015	Biopolymer transport protein exbD tolR
ALEK_RS02800	ENOG4107RBR	Receptor
ALEK_RS02805	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
ALEK_RS02820	ENOG4105CIS	alcohol dehydrogenase
ALEK_RS02855	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ALEK_RS02860	ENOG4105GXZ	Ferredoxin-type protein NapH
ALEK_RS02865	ENOG4108BGM	Quinol dehydrogenase periplasmic component
ALEK_RS02870	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ALEK_RS02880	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ALEK_RS02890	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS02895	ENOG4105EJQ	L-serine dehydratase
ALEK_RS02900	ENOG4105CDA	abc transporter atp-binding protein
ALEK_RS02905	ENOG4105DRP	amino acid AbC transporter
ALEK_RS02910	ENOG4105EZ7	amino acid ABC transporter
ALEK_RS02915	ENOG4107QXX	ABC transporter
ALEK_RS02920	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ALEK_RS02935	ENOG4108I0Q	anthranilate phosphoribosyltransferase
ALEK_RS02940	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ALEK_RS02945	ENOG4105BZU	Histidine kinase
ALEK_RS02955	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS02960	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ALEK_RS02970	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
ALEK_RS02975	ENOG4105K4P	CoA-binding domain protein
ALEK_RS02980	ENOG4105DHQ	Histidine kinase
ALEK_RS02985	ENOG4105ETX	regulatoR
ALEK_RS02990	ENOG4105EIN	peptidylprolyl cis-trans isomerase
ALEK_RS02995	ENOG4105D2N	Aldolase
ALEK_RS03010	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ALEK_RS03030	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
ALEK_RS03035	ENOG4105D7T	ABC transporter
ALEK_RS03065	ENOG4105DZG	Dehydrogenase
ALEK_RS03080	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
ALEK_RS03085	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
ALEK_RS03090	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
ALEK_RS03105	ENOG4105BZU	Histidine kinase
ALEK_RS03110	ENOG4105C26	Dehydrogenase
ALEK_RS03120	ENOG4105M8F	Biopolymer transport protein exbD tolR
ALEK_RS03125	ENOG4105M8K	biopolymer transport protein
ALEK_RS03135	ENOG4105BZU	Histidine kinase
ALEK_RS03140	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ALEK_RS03145	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
ALEK_RS03160	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
ALEK_RS03165	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ALEK_RS03175	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ALEK_RS03185	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
ALEK_RS03190	ENOG4105VIE	preprotein translocase, subunit YajC
ALEK_RS03195	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ALEK_RS03200	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ALEK_RS03225	ENOG4105C8T	Leucyl-tRNA synthetase
ALEK_RS03235	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ALEK_RS03240	ENOG4105DR5	peptidase
ALEK_RS03250	ENOG4105C1J	atp-dependent rna helicase
ALEK_RS03255	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
ALEK_RS03295	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
ALEK_RS03315	ENOG4106MP8	UPF0754 membrane protein
ALEK_RS03320	ENOG4105D7X	high-affinity nickel-transporter
ALEK_RS03340	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ALEK_RS03345	ENOG4105EKE	dihydroorotase
ALEK_RS03350	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ALEK_RS03355	ENOG4105GR3	Histidine kinase
ALEK_RS03365	ENOG4108JA2	transcriptioN-repair coupling factor
ALEK_RS03370	ENOG4105E09	nadh pyrophosphatase
ALEK_RS03385	ENOG4105CBX	hi0933 family
ALEK_RS03430	ENOG4105CBX	hi0933 family
ALEK_RS03435	ENOG4105D48	metallophosphoesterase
ALEK_RS03455	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ALEK_RS03460	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ALEK_RS03465	ENOG4108V3W	Chemotaxis protein, CheW
ALEK_RS03475	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ALEK_RS03480	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ALEK_RS03490	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
ALEK_RS03495	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
ALEK_RS03505	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ALEK_RS03510	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ALEK_RS03520	ENOG4108K01	transcriptional regulator
ALEK_RS03535	ENOG4107YTP	response regulator receiver protein
ALEK_RS03540	ENOG4105ECY	inositol monophosphatase
ALEK_RS03550	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ALEK_RS03555	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
ALEK_RS03560	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
ALEK_RS03565	ENOG4107W1P	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ALEK_RS03570	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
ALEK_RS03585	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ALEK_RS03590	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
ALEK_RS03595	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ALEK_RS03610	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ALEK_RS03630	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ALEK_RS03650	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
ALEK_RS03665	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
ALEK_RS03675	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS03685	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ALEK_RS03690	ENOG4108ZG0	Ompa motb domain protein
ALEK_RS03695	ENOG4105CDV	Ompa motb domain protein
ALEK_RS03700	ENOG4105CDV	Ompa motb domain protein
ALEK_RS03705	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ALEK_RS03710	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ALEK_RS03715	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ALEK_RS03720	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ALEK_RS03725	ENOG4105DC7	peptidase M24
ALEK_RS03730	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ALEK_RS03735	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
ALEK_RS03745	ENOG4105C1J	atp-dependent rna helicase
ALEK_RS03755	ENOG4108IJ2	phosphate acetyltransferase
ALEK_RS03760	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ALEK_RS03765	ENOG41083X2	DNA polymerase III, epsilon subunit
ALEK_RS03775	ENOG4107QN1	sodium solute
ALEK_RS03785	ENOG4107QN1	sodium solute
ALEK_RS03795	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ALEK_RS03805	ENOG4107QN1	sodium solute
ALEK_RS03815	ENOG4108STX	response regulator
ALEK_RS03820	ENOG4105BZU	Histidine kinase
ALEK_RS03925	ENOG4105CEV	competence damage-inducible protein
ALEK_RS03930	ENOG4107RSR	Malate quinone oxidoreductase
ALEK_RS03935	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
ALEK_RS03950	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
ALEK_RS03975	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ALEK_RS03985	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS04000	ENOG4105CE9	30S ribosomal protein S2
ALEK_RS04005	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ALEK_RS04010	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ALEK_RS04020	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ALEK_RS04025	ENOG4105BZU	Histidine kinase
ALEK_RS04030	ENOG4105C59	p-type ATPase
ALEK_RS04045	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
ALEK_RS04050	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ALEK_RS04065	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
ALEK_RS04070	ENOG4107S90	membrAne
ALEK_RS04075	ENOG4105FDK	ABC transporter
ALEK_RS04085	ENOG4105QNR	S1 RNA binding domain protein
ALEK_RS04090	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
ALEK_RS04100	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
ALEK_RS04105	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
ALEK_RS04110	ENOG4105ENA	helicase
ALEK_RS04120	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
ALEK_RS04130	ENOG4105BZS	acriflavin resistance protein
ALEK_RS04145	ENOG4107RDB	Major Facilitator
ALEK_RS04150	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ALEK_RS04175	ENOG410901F	(LipO)protein
ALEK_RS04180	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ALEK_RS04195	ENOG4106AXJ	AraC family transcriptional regulator
ALEK_RS04200	ENOG4108VP3	Lysine exporter protein (LysE YggA)
ALEK_RS04225	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS04230	ENOG4105D64	Mechanosensitive ion channel
ALEK_RS04265	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS04270	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ALEK_RS04275	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS04315	ENOG4105CHR	reductase
ALEK_RS04325	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
ALEK_RS04340	ENOG4105CK2	sodium dicarboxylate symporter
ALEK_RS04355	ENOG4106AXJ	AraC family transcriptional regulator
ALEK_RS04360	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ALEK_RS04385	ENOG4105D7X	high-affinity nickel-transporter
ALEK_RS04405	ENOG4105C28	cystathionine
ALEK_RS04430	ENOG4105DWY	Agmatine deiminase
ALEK_RS04440	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ALEK_RS04450	ENOG4105K63	Thioredoxin
ALEK_RS04455	ENOG4105CNG	UPF0061 protein
ALEK_RS04465	ENOG41067SE	Tetr family transcriptional regulator
ALEK_RS04480	ENOG4105BZS	acriflavin resistance protein
ALEK_RS04500	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
ALEK_RS04530	ENOG4105JSC	dimethylmenaquinone methyltransferase
ALEK_RS04535	ENOG4105D3Y	Na H antiporter
ALEK_RS04545	ENOG4105BZU	Histidine kinase
ALEK_RS04550	ENOG4105VG1	fes assembly suf system protein
ALEK_RS04555	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
ALEK_RS04570	ENOG4105C3K	feS assembly ATPase SufC
ALEK_RS04580	ENOG4105E5Q	amino acid AbC transporter
ALEK_RS04585	ENOG4105EAB	amino acid AbC transporter
ALEK_RS04590	ENOG4105C3J	Cysteine desulfurase
ALEK_RS04615	ENOG4105FQT	
ALEK_RS04620	ENOG4105CH7	arginosuccinase
ALEK_RS04630	ENOG4105CUZ	uba thif-type nad fad binding protein
ALEK_RS04635	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ALEK_RS04640	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
ALEK_RS04660	ENOG4105CSM	endonuclease III
ALEK_RS04665	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
ALEK_RS04685	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
ALEK_RS04705	ENOG4108YZG	isomerase
ALEK_RS04710	ENOG4105C3F	Signal peptidase i
ALEK_RS04715	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ALEK_RS04720	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
ALEK_RS04725	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ALEK_RS04740	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
ALEK_RS04750	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ALEK_RS04760	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
ALEK_RS04765	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
ALEK_RS04775	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
ALEK_RS04780	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
ALEK_RS04785	ENOG4105CRQ	synthase (Component I)
ALEK_RS04795	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ALEK_RS04800	ENOG4105CRK	lysyL-tRNA synthetase
ALEK_RS04810	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
ALEK_RS04815	ENOG4105CDU	Replicative dna helicase
ALEK_RS04855	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
ALEK_RS04860	ENOG4107QP8	phosphohexose isomerase
ALEK_RS04865	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
ALEK_RS04880	ENOG4107QQG	Dehydrogenase
ALEK_RS04885	ENOG4105D2T	synthase
ALEK_RS04890	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
ALEK_RS04895	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ALEK_RS04910	ENOG4105F0R	Cytidylyltransferase
ALEK_RS04925	ENOG4105D2T	synthase
ALEK_RS04930	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
ALEK_RS04960	ENOG4107T4Z	adenosine kinase
ALEK_RS05010	ENOG4105CPQ	Dehydrogenase
ALEK_RS05025	ENOG4105ESV	Glycosyl transferase, family 4
ALEK_RS05050	ENOG4107QKV	phosphomannomutase
ALEK_RS05055	ENOG4105CMR	udp-glucose 4-epimerase
ALEK_RS05060	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
ALEK_RS05065	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ALEK_RS05075	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ALEK_RS05080	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ALEK_RS05085	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ALEK_RS05090	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ALEK_RS05100	ENOG4105CVR	type I restriction-modification system
ALEK_RS05105	ENOG41082EK	Restriction modification system DNA (Specificity
ALEK_RS05130	ENOG4105DZR	Type I site-specific deoxyribonuclease
ALEK_RS05140	ENOG4108C33	Resolvase
ALEK_RS05205	ENOG4105C3G	gtp-binding protein
ALEK_RS05230	ENOG4105NBK	UPF0345 protein
ALEK_RS05245	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
ALEK_RS05250	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ALEK_RS05260	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS05265	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
ALEK_RS05270	ENOG4105CPF	Cell wall formation (By similarity)
ALEK_RS05280	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
ALEK_RS05325	ENOG41062JF	Transcriptional regulator
ALEK_RS05350	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
ALEK_RS05355	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ALEK_RS05360	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ALEK_RS05365	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
ALEK_RS05370	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ALEK_RS05375	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ALEK_RS05380	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ALEK_RS05385	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ALEK_RS05390	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ALEK_RS05395	ENOG41084HJ	50s ribosomal protein l29
ALEK_RS05400	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ALEK_RS05405	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ALEK_RS05410	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ALEK_RS05415	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ALEK_RS05420	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
ALEK_RS05425	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ALEK_RS05430	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ALEK_RS05435	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ALEK_RS05440	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ALEK_RS05445	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
ALEK_RS05450	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
ALEK_RS05455	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
ALEK_RS05460	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
ALEK_RS05470	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
ALEK_RS05480	ENOG4105C9M	aspartyl-trna synthetase
ALEK_RS05495	ENOG4105CCT	upf0313 protein
ALEK_RS05500	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ALEK_RS05505	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS05520	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ALEK_RS05525	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ALEK_RS05550	ENOG4108V06	Glutathione peroxidase
ALEK_RS05555	ENOG4105BZU	Histidine kinase
ALEK_RS05580	ENOG4105DAA	L-lactate
ALEK_RS05590	ENOG4105BZU	Histidine kinase
ALEK_RS05625	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ALEK_RS05625	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ALEK_RS05640	ENOG4105MEW	serine threonine protein phosphatase
ALEK_RS05645	ENOG4105D17	glycoside hydrolase, family 3 domain protein
ALEK_RS05675	ENOG4105CGK	Exodeoxyribonuclease III
ALEK_RS05715	ENOG4105DCM	major facilitator superfamily
ALEK_RS05740	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_RS05785	ENOG4105D5U	fad dependent oxidoreductase
ALEK_RS05790	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ALEK_RS05795	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ALEK_RS05815	ENOG4105CQZ	Histidine kinase
ALEK_RS05820	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS05825	ENOG4108IJ0	Aspartate ammonia-lyase
ALEK_RS05835	ENOG41090A1	ferritin
ALEK_RS05845	ENOG4105BZU	Histidine kinase
ALEK_RS05855	ENOG4105BZU	Histidine kinase
ALEK_RS05865	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
ALEK_RS05875	ENOG4105F1N	DNA alkylation repair
ALEK_RS05880	ENOG4108Z66	YbaK ebsC protein
ALEK_RS05885	ENOG4105C7I	Dehydrogenase
ALEK_RS05910	ENOG4105F1S	paraquat-inducible protein a
ALEK_RS05915	ENOG4105DY2	Paraquat-inducible protein b
ALEK_RS05920	ENOG4105C94	Transporter
ALEK_RS05925	ENOG4108IJ7	Glycine betaine
ALEK_RS05930	ENOG4108HQS	Glycine betaine
ALEK_RS05935	ENOG4105GIJ	Glycine betaine
ALEK_RS05945	ENOG4105GIJ	Glycine betaine
ALEK_RS05955	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
ALEK_RS05970	ENOG4105CGD	Nad-dependent epimerase dehydratase
ALEK_RS05985	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
ALEK_RS06010	ENOG4105EGI	Transcriptional regulator
ALEK_RS06030	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS06035	ENOG4108JYZ	YitT family
ALEK_RS06045	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS06090	ENOG4105BZS	acriflavin resistance protein
ALEK_RS06095	ENOG4105ETX	regulatoR
ALEK_RS06115	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS06140	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ALEK_RS06165	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ALEK_RS06190	ENOG4108URH	decarboxylase
ALEK_RS06200	ENOG4105DHT	Metal Dependent Phosphohydrolase
ALEK_RS06205	ENOG4107VQW	regulatoR
ALEK_RS06210	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ALEK_RS06220	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_RS06230	ENOG4105E7W	lamb ycsf family protein
ALEK_RS06250	ENOG4105BZU	Histidine kinase
ALEK_RS06265	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS06270	ENOG4105C1J	atp-dependent rna helicase
ALEK_RS06275	ENOG4105BZU	Histidine kinase
ALEK_RS06280	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
ALEK_RS06290	ENOG4105D05	Receptor
ALEK_RS06295	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
ALEK_RS06300	ENOG4105E2Y	ABC, transporter
ALEK_RS06325	ENOG4107ENK	receptor
ALEK_RS06330	ENOG41074H6	response regulator
ALEK_RS06350	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS06355	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
ALEK_RS06360	ENOG4105BZU	Histidine kinase
ALEK_RS06370	ENOG4108IAB	Phoh family
ALEK_RS06390	ENOG4105BZU	Histidine kinase
ALEK_RS06395	ENOG4105CJZ	response regulator
ALEK_RS06405	ENOG4105EQK	-acetyltransferase
ALEK_RS06410	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
ALEK_RS06420	ENOG4108JYZ	YitT family
ALEK_RS06435	ENOG4105BZU	Histidine kinase
ALEK_RS06440	ENOG4105BZU	Histidine kinase
ALEK_RS06445	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS06485	ENOG4105E5Q	amino acid AbC transporter
ALEK_RS06490	ENOG4105EAB	amino acid AbC transporter
ALEK_RS06505	ENOG4105EM7	Selenocysteine-specific translation elongation factor
ALEK_RS06510	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
ALEK_RS06530	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
ALEK_RS06535	ENOG4105BZU	Histidine kinase
ALEK_RS06540	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS06545	ENOG4105BZU	Histidine kinase
ALEK_RS06550	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS06555	ENOG4107T9Q	phosphonate abc transporter
ALEK_RS06560	ENOG4108VA1	ABC transporter
ALEK_RS06565	ENOG4105S7S	phosphonate abc transporter
ALEK_RS06585	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ALEK_RS06615	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ALEK_RS06620	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ALEK_RS06625	ENOG4105QAX	Iron-sulfur
ALEK_RS06635	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
ALEK_RS06655	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ALEK_RS06660	ENOG4105C8W	ABC transporter
ALEK_RS06665	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
ALEK_RS06725	ENOG4108R99	pseudouridine synthase
ALEK_RS06735	ENOG4105BZU	Histidine kinase
ALEK_RS06740	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
ALEK_RS06805	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ALEK_RS06840	ENOG4105KME	endoribonuclease L-psp
ALEK_RS06845	ENOG4107QMZ	Dehydrogenase
ALEK_RS06850	ENOG4105BZG	amino acid carrier protein
ALEK_RS06855	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ALEK_RS06860	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
ALEK_RS06865	ENOG4108DMH	HTH_ARAC
ALEK_RS06870	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
ALEK_RS06885	ENOG4105I93	response regulator
ALEK_RS06895	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ALEK_RS06930	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ALEK_RS06960	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ALEK_RS06965	ENOG4105BZU	Histidine kinase
ALEK_RS06970	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ALEK_RS06980	ENOG4105BZU	Histidine kinase
ALEK_RS06990	ENOG4108V3W	Chemotaxis protein, CheW
ALEK_RS06995	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS07000	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_RS07005	ENOG4105CBS	Chea signal transduction histidine kinase
ALEK_RS07015	ENOG4107YTP	response regulator receiver protein
ALEK_RS07020	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ALEK_RS07035	ENOG410812K	response regulator receiver protein
ALEK_RS07040	ENOG4105BZU	Histidine kinase
ALEK_RS07055	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ALEK_RS07100	ENOG4105BZU	Histidine kinase
ALEK_RS07110	ENOG4105KCK	Peptidoglycan-associated lipoprotein
ALEK_RS07115	ENOG4107R7Y	intracellular protease Pfpi family
ALEK_RS07120	ENOG4105J4Q	Transcriptional regulator
ALEK_RS07135	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ALEK_RS07160	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ALEK_RS07185	ENOG4105CHM	Aminotransferase
ALEK_RS07195	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
ALEK_RS07220	ENOG410903C	(LipO)protein
ALEK_RS07225	ENOG4105DR5	peptidase
ALEK_RS07230	ENOG4105DAN	ATP-dependent protease
ALEK_RS07235	ENOG4108IJ0	Aspartate ammonia-lyase
ALEK_RS07240	ENOG4105CDY	transcriptional regulatory protein
ALEK_RS07285	ENOG4105CJ2	(LipO)protein
ALEK_RS07290	ENOG4105ERG	peptidase m48, ste24p
ALEK_RS07300	ENOG4107QPN	acyl-Coa dehydrogenase
ALEK_RS07305	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ALEK_RS07315	ENOG4108IQE	Amp-dependent synthetase and ligase
ALEK_RS07320	ENOG4108UZ3	Transporter
ALEK_RS07330	ENOG4105C2N	RNA methyltransferase TrmH family group 3
ALEK_RS07335	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ALEK_RS07345	ENOG4105C9Q	fumarate hydratase class II
ALEK_RS07360	ENOG4105C26	Dehydrogenase
ALEK_RS07395	ENOG4105EI2	Pseudouridine synthase
ALEK_RS07420	ENOG4105E3S	small subunit
ALEK_RS07425	ENOG4105DPX	Hydrogenase, large subunit
ALEK_RS07455	ENOG4105EUZ	Beta-lactamase domain protein
ALEK_RS07460	ENOG4105E3S	small subunit
ALEK_RS07465	ENOG4105DPX	Hydrogenase, large subunit
ALEK_RS07470	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
ALEK_RS07475	ENOG4108USZ	hydrogenase
ALEK_RS07480	ENOG4108P97	
ALEK_RS07495	ENOG4108RCM	Nitroreductase
ALEK_RS07530	ENOG4105C8J	)-transporter
ALEK_RS07535	ENOG41084TB	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
ALEK_RS07540	ENOG4107QMS	site-determining protein
ALEK_RS07545	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
ALEK_RS07550	ENOG4105C1J	atp-dependent rna helicase
ALEK_RS07565	ENOG4105CA0	peroxidase
ALEK_RS07570	ENOG4108IXY	short-chain dehydrogenase reductase
ALEK_RS07580	ENOG4105E1F	short-chain dehydrogenase reductase
ALEK_RS07590	ENOG4105VCH	membrane
ALEK_RS07600	ENOG4105BZU	Histidine kinase
ALEK_RS07615	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ALEK_RS07640	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS07645	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
ALEK_RS07650	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
ALEK_RS07655	ENOG4105CQS	hydrogenase expression formation protein HypD
ALEK_RS07660	ENOG4105C45	hydrogenase expression formation protein (HypE)
ALEK_RS07665	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ALEK_RS07670	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
ALEK_RS07690	ENOG4105C32	Amino acid ABC transporter (Permease)
ALEK_RS07695	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
ALEK_RS07700	ENOG4105C0Z	ABC transporter
ALEK_RS07705	ENOG4108IV0	ABC, transporter
ALEK_RS07710	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
ALEK_RS07735	ENOG4105C25	Primosomal protein n'
ALEK_RS07745	ENOG4107QX8	SPFH domain, Band 7 family protein
ALEK_RS07750	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
ALEK_RS07760	ENOG4105C5H	ABC transporter
ALEK_RS07770	ENOG4105KPY	Small multidrug resistance protein
ALEK_RS07785	ENOG4106HK8	GPR1 FUN34 yaaH family protein
ALEK_RS07800	ENOG4105CAK	Cell division ATP-binding protein ftsE
ALEK_RS07805	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ALEK_RS07815	ENOG4105C34	Pseudouridine synthase
ALEK_RS07820	ENOG4105CNI	cell division protein FtsW
ALEK_RS07825	ENOG4105CYW	agmatinase
ALEK_RS07845	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ALEK_RS07850	ENOG4105NBK	UPF0345 protein
ALEK_RS07870	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ALEK_RS07875	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ALEK_RS07880	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
ALEK_RS07895	ENOG41067V7	50S ribosomal protein L36
ALEK_RS07900	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ALEK_RS07905	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
ALEK_RS07910	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ALEK_RS07915	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ALEK_RS07920	ENOG4108ZT0	50S ribosomal protein l17
ALEK_RS07925	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ALEK_RS07930	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ALEK_RS07975	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ALEK_RS08000	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ALEK_RS08005	ENOG4108URH	decarboxylase
ALEK_RS08020	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ALEK_RS08030	ENOG4105CUC	YeeE YedE family protein
ALEK_RS08045	ENOG4105N14	lysine exporter protein LysE YggA
ALEK_RS08050	ENOG4105N14	lysine exporter protein LysE YggA
ALEK_RS08065	ENOG4105GAV	receptor
ALEK_RS08085	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
ALEK_RS08095	ENOG4105DWV	Homoserine O-trans-acetylase
ALEK_RS08105	ENOG4105D06	uba thif-type nad fad binding protein
ALEK_RS08110	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
ALEK_RS08135	ENOG4108JJA	ABC, transporter
ALEK_RS08185	ENOG4105D49	3-dehydroquinate synthase
ALEK_RS08195	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ALEK_RS08200	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ALEK_RS08210	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
ALEK_RS08215	ENOG4105C8P	)-transporter
ALEK_RS08220	ENOG4105C98	muts2 protein
ALEK_RS08240	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
ALEK_RS08255	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
ALEK_RS08260	ENOG4105KK4	UPF0060 membrane protein
ALEK_RS08275	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
ALEK_RS08285	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ALEK_RS08295	ENOG4105DKW	ABC transporter
ALEK_RS08315	ENOG4105T16	Transcriptional regulator (AraC family)
ALEK_RS08320	ENOG4108V1U	phospholipid-binding protein
ALEK_RS08340	ENOG4105BZU	Histidine kinase
ALEK_RS08355	ENOG4105DUM	transcriptional regulator, lysR family
ALEK_RS08360	ENOG4105HMI	Membrane
ALEK_RS08375	ENOG4105KVH	Transcriptional regulator
ALEK_RS08380	ENOG4105NF4	modulator of drug activity
ALEK_RS08390	ENOG4108RCM	Nitroreductase
ALEK_RS08400	ENOG4105WH1	Two component transcriptional regulator luxr family
ALEK_RS08410	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ALEK_RS08415	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_RS08420	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ALEK_RS08440	ENOG4105E0C	molybdate abc transporter
ALEK_RS08450	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
ALEK_RS08455	ENOG4105F4R	Transcriptional regulator mode
ALEK_RS08475	ENOG4105GR3	Histidine kinase
ALEK_RS08485	ENOG41066UZ	arginase EC 3.5.3.1
ALEK_RS08495	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
ALEK_RS08510	ENOG4105BZU	Histidine kinase
ALEK_RS08515	ENOG4105BZU	Histidine kinase
ALEK_RS08520	ENOG4105C5H	ABC transporter
ALEK_RS08525	ENOG4108S4H	thioesterase Superfamily protein
ALEK_RS08535	ENOG4105BZU	Histidine kinase
ALEK_RS08540	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ALEK_RS08550	ENOG4105BZU	Histidine kinase
ALEK_RS08590	ENOG4105CIN	aminoacyl-histidine dipeptidase
ALEK_RS08595	ENOG4105DHT	Metal Dependent Phosphohydrolase
ALEK_RS08635	ENOG4108STX	response regulator
ALEK_RS08640	ENOG4105BZU	Histidine kinase
ALEK_RS08655	ENOG4105EMU	Dehydrogenase
ALEK_RS08660	ENOG4105CRE	cytochrome C
ALEK_RS08665	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
ALEK_RS08675	ENOG4105BZU	Histidine kinase
ALEK_RS08680	ENOG4105C5X	domain protein
ALEK_RS08690	ENOG4107414	GntR family transcriptional regulator
ALEK_RS08695	ENOG4105D5T	phosphonate abc transporter
ALEK_RS08725	ENOG4105FT8	Phosphonate metabolism
ALEK_RS08730	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
ALEK_RS08735	ENOG4105HRV	phosphonate c-p lyase system protein phnl
ALEK_RS08740	ENOG4105FD8	phosphonate metabolism protein PhnM
ALEK_RS08750	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS08755	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
ALEK_RS08790	ENOG4105QNF	Outer membrane lipoprotein
ALEK_RS08805	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
ALEK_RS08820	ENOG4105QNF	Outer membrane lipoprotein
ALEK_RS08825	ENOG4105CT4	transporter
ALEK_RS08835	ENOG4107FW0	short-chain dehydrogenase reductase
ALEK_RS08855	ENOG4108JJA	ABC, transporter
ALEK_RS08875	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ALEK_RS08880	ENOG4105BZU	Histidine kinase
ALEK_RS08885	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ALEK_RS08890	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
ALEK_RS08895	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_RS08900	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS08910	ENOG4108Z0R	Transferase
ALEK_RS08925	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
ALEK_RS08935	ENOG4105CDH	Citrulline--aspartate ligase
ALEK_RS08945	ENOG4107S1N	anthranilate phosphoribosyltransferase
ALEK_RS08950	ENOG4105K8N	protein family UPF0079, ATPase
ALEK_RS08955	ENOG4108IUZ	ABC transporter
ALEK_RS08960	ENOG4105BZU	Histidine kinase
ALEK_RS08965	ENOG4105BZU	Histidine kinase
ALEK_RS08970	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
ALEK_RS08975	ENOG4105C2M	dna polymerase I
ALEK_RS08995	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
ALEK_RS09000	ENOG4105DF6	Fe-S oxidoreductase
ALEK_RS09005	ENOG4105D4P	Coproporphyrinogen iii oxidase
ALEK_RS09010	ENOG4105DBV	ornithine carbamoyltransferase
ALEK_RS09015	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ALEK_RS09030	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS09035	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_RS09040	ENOG4105D52	delta-aminolevulinic acid dehydratase
ALEK_RS09050	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ALEK_RS09125	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
ALEK_RS09130	ENOG4105D9Q	decarboxylase (Beta subunit)
ALEK_RS09155	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ALEK_RS09165	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ALEK_RS09175	ENOG4105RWS	endonuclease I
ALEK_RS09195	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ALEK_RS09205	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
ALEK_RS09210	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALEK_RS09220	ENOG4105EEI	dihydropteroate synthase
ALEK_RS09235	ENOG4105CFH	Aspartokinase
ALEK_RS09240	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
ALEK_RS09245	ENOG4105CSA	Coproporphyrinogen iii oxidase
ALEK_RS09250	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ALEK_RS09255	ENOG4105DGW	oligopeptidase A
ALEK_RS09270	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ALEK_RS09275	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ALEK_RS09280	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
ALEK_RS09285	ENOG4105BZU	Histidine kinase
ALEK_RS09290	ENOG4105CBS	Chea signal transduction histidine kinase
ALEK_RS09295	ENOG4108VYJ	response regulator receiver protein
ALEK_RS09300	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ALEK_RS09310	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
ALEK_RS09330	ENOG4105CHH	sulfate transporter
ALEK_RS09335	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ALEK_RS09345	ENOG4105CNU	cell division protein FtsK
ALEK_RS09350	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALEK_RS09355	ENOG4108ZP8	Acetolactate synthase small subunit
ALEK_RS09360	ENOG4105C7K	acetolactate synthase
ALEK_RS09375	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
ALEK_RS09385	ENOG4105CHH	sulfate transporter
ALEK_RS09410	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
ALEK_RS09425	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ALEK_RS09440	ENOG4105CGY	Dna recombination protein
ALEK_RS09445	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
ALEK_RS09450	ENOG4105BZU	Histidine kinase
ALEK_RS09460	ENOG4107YD3	Thioesterase
ALEK_RS09500	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ALEK_RS09505	ENOG4108JQ5	ABC transporter
ALEK_RS09510	ENOG4107R73	Mate efflux family protein
ALEK_RS09520	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_RS09525	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS09530	ENOG4105CPC	Aldo Keto reductase
ALEK_RS09560	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
ALEK_RS09580	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
ALEK_RS09585	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
ALEK_RS09590	ENOG4108P62	biosynthesis protein (CbiG)
ALEK_RS09595	ENOG4105E4R	Precorrin-3B C17-methyltransferase
ALEK_RS09610	ENOG4105E7U	AraC family transcriptional regulator
ALEK_RS09620	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ALEK_RS09630	ENOG4105BZU	Histidine kinase
ALEK_RS09650	ENOG4105F2W	methyltransferase
ALEK_RS09655	ENOG4108IU2	vtamin B12-transporter permease
ALEK_RS09660	ENOG4108JJB	ABC transporter
ALEK_RS09685	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ALEK_RS09695	ENOG4107QX8	SPFH domain, Band 7 family protein
ALEK_RS09705	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_RS09715	ENOG4105CIY	formyltetrahydrofolate deformylase
ALEK_RS09725	ENOG4105C26	Dehydrogenase
ALEK_RS09730	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
ALEK_RS09745	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
ALEK_RS09760	ENOG4108IJ9	(ABC) transporter
ALEK_RS09765	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
ALEK_RS09775	ENOG4105FDP	GntR family transcriptional regulator
ALEK_RS09780	ENOG4105C6K	Malic enzyme
ALEK_RS09785	ENOG4108IJ0	Aspartate ammonia-lyase
ALEK_RS09790	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ALEK_RS09795	ENOG4105BZU	Histidine kinase
ALEK_RS09800	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
ALEK_RS09820	ENOG4105E2X	shikimate dehydrogenase
ALEK_RS09840	ENOG4105CEM	UPF0597 protein
ALEK_RS09845	ENOG4105EGI	Transcriptional regulator
ALEK_RS09855	ENOG4105CJW	magnesium transporter
ALEK_RS09865	ENOG4108UHV	Lipoprotein
ALEK_RS09870	ENOG4106032	Glutathionylspermidine synthase
ALEK_RS09905	ENOG4105EKT	)-iron permease
ALEK_RS09910	ENOG41088SP	formiminoglutamate hydrolase
ALEK_RS09915	ENOG4105CI2	imidazolone-5-propionate hydrolase
ALEK_RS09920	ENOG4105CGP	Urocanate hydratase
ALEK_RS09930	ENOG4105FDP	GntR family transcriptional regulator
ALEK_RS09965	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
ALEK_RS09975	ENOG4105C4K	Nad synthetase
ALEK_RS09995	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ALEK_RS10005	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ALEK_RS10010	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
ALEK_RS10040	ENOG4105C8J	)-transporter
ALEK_RS10060	ENOG4105BZW	Glycerate kinase
ALEK_RS10065	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
ALEK_RS10080	ENOG4105EYW	Ion transport protein
ALEK_RS10100	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ALEK_RS10115	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS10125	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
ALEK_RS10170	ENOG4105XDF	Protein of unknown function (DUF1272)
ALEK_RS10180	ENOG4106MWK	domain protein
ALEK_RS10195	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS10200	ENOG4105BZU	Histidine kinase
ALEK_RS10205	ENOG4107QUV	Domain protein
ALEK_RS10210	ENOG4108M3P	Membrane
ALEK_RS10215	ENOG4108K0D	peptidase, M48
ALEK_RS10220	ENOG4105EYH	Exonuclease
ALEK_RS10230	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS10240	ENOG4108HGU	Histidine kinase
ALEK_RS10245	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_RS10275	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
ALEK_RS10290	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ALEK_RS10295	ENOG4107XM9	(LipO)protein
ALEK_RS10310	ENOG4105BZU	Histidine kinase
ALEK_RS10320	ENOG4105DJI	Methylaspartate mutase, E subunit
ALEK_RS10330	ENOG4105CEY	Amp-dependent synthetase and ligase
ALEK_RS10360	ENOG4105F0I	Aminotransferase
ALEK_RS10380	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ALEK_RS10390	ENOG410841J	DNA-binding protein Hu
ALEK_RS10405	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ALEK_RS10415	ENOG4105DY9	regulatoR
ALEK_RS10420	ENOG4108HRK	Histidine kinase
ALEK_RS10425	ENOG4105EWK	phytoene
ALEK_RS10430	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
ALEK_RS10435	ENOG4107SEY	Conserved Protein
ALEK_RS10440	ENOG4105CQ7	ATP-dependent helicase
ALEK_RS10455	ENOG4105C1J	atp-dependent rna helicase
ALEK_RS10470	ENOG4105ID8	Transcriptional regulator, ARAC family
ALEK_RS10480	ENOG4105I03	Flagellin
ALEK_RS10480	ENOG4105I03	Flagellin
ALEK_RS10500	ENOG4105ETX	regulatoR
ALEK_RS10525	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS10530	ENOG4105BZ1	(ABC) transporter
ALEK_RS10540	ENOG4105DSF	transport protein
ALEK_RS10555	ENOG410829K	Lysine exporter protein (Lyse ygga)
ALEK_RS10565	ENOG4105ZGC	lipoprotein carrier protein
ALEK_RS10570	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ALEK_RS10575	ENOG4105D60	lipoprotein releasing system transmembrane protein
ALEK_RS10580	ENOG4105BZU	Histidine kinase
ALEK_RS10590	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS10605	ENOG4105E9K	Isocitrate dehydrogenase
ALEK_RS10610	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ALEK_RS10620	ENOG4105PGM	cation diffusion facilitator family transporter
ALEK_RS10635	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
ALEK_RS10645	ENOG4105DVC	DnaJ domain protein
ALEK_RS10650	ENOG4105KNI	merR family transcriptional Regulator
ALEK_RS10655	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ALEK_RS10660	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
ALEK_RS10670	ENOG4105C7H	Helicase, RecD TraA family
ALEK_RS10695	ENOG4105ERG	peptidase m48, ste24p
ALEK_RS10715	ENOG4105CJN	penicillin-binding protein
ALEK_RS10725	ENOG4105HKU	nucleoside recognition domain-containing protein
ALEK_RS10730	ENOG4105CN7	Flagellar biosynthetic protein FliP
ALEK_RS10735	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
ALEK_RS10755	ENOG4105BZS	acriflavin resistance protein
ALEK_RS10760	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS10765	ENOG4105EB3	Histidine kinase
ALEK_RS10770	ENOG4105DEF	Extracellular solute-binding protein, family 5
ALEK_RS10775	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ALEK_RS10780	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ALEK_RS10790	ENOG4108JQ7	(ABC) transporter
ALEK_RS10795	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
ALEK_RS10815	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
ALEK_RS10830	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
ALEK_RS10835	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
ALEK_RS10840	ENOG4105K6T	rare lipoprotein A
ALEK_RS10845	ENOG4105F8V	Hydrolase, tatD family
ALEK_RS10855	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
ALEK_RS10860	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
ALEK_RS10865	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
ALEK_RS10890	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
ALEK_RS10895	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
ALEK_RS10900	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
ALEK_RS10905	ENOG4105CUT	histidyl-tRNA synthetase
ALEK_RS10910	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
ALEK_RS10915	ENOG4105D7W	serine acetyltransferase
ALEK_RS10930	ENOG4108I0Z	Aconitate hydratase
ALEK_RS10950	ENOG4105CH6	catalase
ALEK_RS10955	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ALEK_RS10975	ENOG4108JU6	CBS domain protein
ALEK_RS10980	ENOG4108UHE	carbonic anhydrase
ALEK_RS10985	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
ALEK_RS11000	ENOG4105DSF	transport protein
ALEK_RS11020	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
ALEK_RS11030	ENOG4105BZU	Histidine kinase
ALEK_RS11035	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
ALEK_RS11040	ENOG4105VIG	Sec-independent protein translocase protein TatC
ALEK_RS11055	ENOG4105CTQ	phosphohexokinase
ALEK_RS11060	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
ALEK_RS11065	ENOG4105DR4	Methyltransferase
ALEK_RS11070	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ALEK_RS11075	ENOG4105BZU	Histidine kinase
ALEK_RS11085	ENOG4108MRH	transcriptional regulatory protein
ALEK_RS11095	ENOG4107QN2	dihydrolipoyl dehydrogenase
ALEK_RS11105	ENOG4105W4W	Transcriptional regulator
ALEK_RS11110	ENOG4105UEI	Transcriptional Regulator AraC Family
ALEK_RS11115	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ALEK_RS11130	ENOG4105PW4	Sugar fermentation stimulation protein homolog
ALEK_RS11145	ENOG4105W4W	Transcriptional regulator
ALEK_RS11200	ENOG4105M4H	endoribonuclease L-psp
ALEK_RS11205	ENOG4105EN6	Membrane
ALEK_RS11210	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS11215	ENOG4105BZU	Histidine kinase
ALEK_RS11225	ENOG4105BZU	Histidine kinase
ALEK_RS11250	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
ALEK_RS11260	ENOG4108VKQ	nitriC oxide reductase
ALEK_RS11275	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
ALEK_RS11280	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ALEK_RS11300	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ALEK_RS11330	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
ALEK_RS11340	ENOG4105CF7	AraC family transcriptional regulator
ALEK_RS11345	ENOG4105NF4	modulator of drug activity
ALEK_RS11355	ENOG4105C5I	Dehydrogenase
ALEK_RS11360	ENOG4105CTD	carboxy-peptidase
ALEK_RS11425	ENOG4105D5K	Hemolysin activator protein
ALEK_RS11430	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS11435	ENOG4105BZU	Histidine kinase
ALEK_RS11440	ENOG4107VQW	regulatoR
ALEK_RS11490	ENOG4105VCQ	rubredoxin
ALEK_RS11510	ENOG4105FE9	pseudouridine synthase
ALEK_RS11550	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ALEK_RS11570	ENOG4105M4H	endoribonuclease L-psp
ALEK_RS11590	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ALEK_RS11600	ENOG4105DN9	Na H antiporter
ALEK_RS11605	ENOG4108IYU	L-aspartate oxidase
ALEK_RS11615	ENOG4108VKG	metal-dependent hydrolase
ALEK_RS11625	ENOG41076HS	cation diffusion facilitator family transporter
ALEK_RS11630	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
ALEK_RS11640	ENOG4105DHT	Metal Dependent Phosphohydrolase
ALEK_RS11645	ENOG4105F8J	Adenylate Guanylate cyclase
ALEK_RS11675	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS11680	ENOG4105BZU	Histidine kinase
ALEK_RS11695	ENOG4105D3Q	Sugar transferase
ALEK_RS11700	ENOG4108TJN	glycosyl transferase group 1
ALEK_RS11710	ENOG4108KBE	Glycosyl transferase, family 2
ALEK_RS11725	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
ALEK_RS11740	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
ALEK_RS11785	ENOG4105D7W	serine acetyltransferase
ALEK_RS11815	ENOG4105C5H	ABC transporter
ALEK_RS11820	ENOG4105KTH	gatB Yqey
ALEK_RS11825	ENOG4105BZU	Histidine kinase
ALEK_RS11840	ENOG4105DHT	Metal Dependent Phosphohydrolase
ALEK_RS11880	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ALEK_RS11890	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ALEK_RS11900	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ALEK_RS11915	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
ALEK_RS11925	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_RS11945	ENOG4105ES5	Histidine kinase
ALEK_RS11975	ENOG4105ETX	regulatoR
ALEK_RS11980	ENOG4105DHQ	Histidine kinase
ALEK_RS11990	ENOG4105C5H	ABC transporter
ALEK_RS12005	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ALEK_RS12015	ENOG4105CX6	glutaminyL-tRNA synthetase
ALEK_RS12020	ENOG4105CA0	peroxidase
ALEK_RS12025	ENOG4105BZU	Histidine kinase
ALEK_RS12030	ENOG4105JAB	phenazine biosynthesis protein, phzf family
ALEK_RS12035	ENOG41075H3	AraC family transcriptional regulator
ALEK_RS12080	ENOG4105E1F	short-chain dehydrogenase reductase
ALEK_RS12085	ENOG4107S6Z	Na H antiporter
ALEK_RS12100	ENOG4107VQW	regulatoR
ALEK_RS12110	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ALEK_RS12115	ENOG4105EFX	secretion protein, HlyD family
ALEK_RS12120	ENOG4105KK7	inner membrane protein YiaW
ALEK_RS12130	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ALEK_RS12135	ENOG4106H78	methyltransferase
ALEK_RS12145	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
ALEK_RS12155	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALEK_RS12160	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ALEK_RS12165	ENOG4105N14	lysine exporter protein LysE YggA
ALEK_RS12175	ENOG4108WZ2	response regulator
ALEK_RS12185	ENOG4105NQN	cytochrome C
ALEK_RS12190	ENOG4105IPS	esterase
ALEK_RS12200	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
ALEK_RS12210	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ALEK_RS12225	ENOG4108RAC	Rubrerythrin
ALEK_RS12230	ENOG4108RAC	Rubrerythrin
ALEK_RS12240	ENOG4105CJR	Integral membrane protein (MviN
ALEK_RS12250	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ALEK_RS12255	ENOG4105CCU	oxidase (Subunit III)
ALEK_RS12265	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
ALEK_RS12275	ENOG4105BZ1	(ABC) transporter
ALEK_RS12280	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
ALEK_RS12295	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ALEK_RS12300	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
ALEK_RS12305	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
ALEK_RS12310	ENOG4105DZP	Membrane-associated zinc metalloprotease
ALEK_RS12315	ENOG4105DFA	alanine racemase domain protein
ALEK_RS12320	ENOG4105VSH	4-oxalocrotonate tautomerase
ALEK_RS12340	ENOG4105BZU	Histidine kinase
ALEK_RS12345	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ALEK_RS12355	ENOG4105QTX	Pfam:UPF0153
ALEK_RS12360	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
ALEK_RS12370	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
ALEK_RS12375	ENOG4105DQU	oxidoreductase, subunit beta
ALEK_RS12385	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ALEK_RS12390	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ALEK_RS12395	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
ALEK_RS12400	ENOG4105DJV	ribulose-phosphate 3-epimerase
ALEK_RS12405	ENOG4105HDD	phospholipase
ALEK_RS12415	ENOG4107VIJ	nudix hydrolase
ALEK_RS12435	ENOG4108VPT	UPF0234 protein
ALEK_RS12440	ENOG4105C2W	permease
ALEK_RS12445	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
ALEK_RS12460	ENOG4105M08	Membrane
ALEK_RS12470	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
ALEK_RS12475	ENOG4105C7N	Xanthine uracil vitamin C permease
ALEK_RS12490	ENOG4105VG1	fes assembly suf system protein
ALEK_RS12495	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ALEK_RS12500	ENOG4105EQD	regulatoR
ALEK_RS12565	ENOG41082XB	radical SAM domain protein
ALEK_RS12570	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
ALEK_RS12580	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ALEK_RS12595	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
ALEK_RS12600	ENOG4107SVH	Potassium channel protein
ALEK_RS12605	ENOG4105VB9	50S ribosomal protein l28
ALEK_RS12620	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
ALEK_RS12630	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
ALEK_RS12635	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
ALEK_RS12640	ENOG4105DKP	glycosyl transferase, family 9
ALEK_RS12645	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
ALEK_RS12655	ENOG4105M5K	heptosyltransferase
ALEK_RS12660	ENOG4105D16	lipopolysaccharide heptosyltransferase i
ALEK_RS12665	ENOG4105CPK	Glycosyl transferase (Group 1
ALEK_RS12690	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ALEK_RS12695	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ALEK_RS12705	ENOG4106WTF	Glycosyl transferase, family 2
ALEK_RS12715	ENOG4105D16	lipopolysaccharide heptosyltransferase i
ALEK_RS12725	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
ALEK_RS12730	ENOG4105ECY	inositol monophosphatase
ALEK_RS12735	ENOG4105BZ8	glutamate synthase
ALEK_RS12740	ENOG4105CBC	glutamate synthase
ALEK_RS12745	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ALEK_RS12750	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
ALEK_RS12755	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_RS12775	ENOG4108UJV	acyl-CoA thioesterase i
ALEK_RS12780	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ALEK_RS12810	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
ALEK_RS12910	ENOG4105WH1	Two component transcriptional regulator luxr family
ALEK_RS12965	ENOG4105CQZ	Histidine kinase
ALEK_RS12970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ALEK_RS13065	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
ALEK_RS13070	ENOG4105M7K	Involved in the transcription termination process (By similarity)
ALEK_RS13075	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
ALEK_RS13080	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
ALEK_RS13095	ENOG4105CBC	glutamate synthase
ALEK_RS13105	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ALEK_RS13135	ENOG4107QHF	type ii secretion system protein e
ALEK_RS13140	ENOG4105GVR	general secretion pathway protein D
ALEK_RS13180	ENOG4108VAU	general secretion pathway protein G
ALEK_RS13185	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
ALEK_RS13190	ENOG4105DX0	Hemolysin A
ALEK_RS13200	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
ALEK_RS13205	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALEK_RS13215	ENOG4105CQB	FAD linked oxidase domain protein
ALEK_RS13255	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
ALEK_RS13260	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
ALEK_RS13265	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ALEK_RS13280	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
ALEK_RS13290	ENOG4105M8F	Biopolymer transport protein exbD tolR
ALEK_RS13295	ENOG4105E02	MotA TolQ exbB proton channel
ALEK_RS13300	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ALEK_RS13305	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
ALEK_RS13310	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
ALEK_RS13315	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
ALEK_RS13320	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ALEK_RS13325	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
ALEK_RS13335	ENOG4105FA0	parb-like partition protein
ALEK_RS13340	ENOG4107QJE	Chromosome Partitioning Protein
ALEK_RS13355	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ALEK_RS13360	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ALEK_RS13365	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ALEK_RS13370	ENOG4105K46	50S ribosomal protein l27
ALEK_RS13375	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
ALEK_RS13380	ENOG4105KME	endoribonuclease L-psp
ALEK_RS13385	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ALEK_RS13395	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
ALEK_RS13400	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ALEK_RS13405	ENOG4105D0M	Protease HtpX homolog
ALEK_RS13410	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ALEK_RS13425	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
ALEK_RS13435	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ALEK_RS13440	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
ALEK_RS13450	ENOG4105VG0	50S ribosomal protein l34
ALEK_RS13460	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ALEK_RS13480	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ALEK_RS13495	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ALEK_RS13500	ENOG4105E0X	reductase
ALEK_RS13505	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS13510	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS13515	ENOG4105BZU	Histidine kinase
ALEK_RS13520	ENOG4105CBC	glutamate synthase
ALEK_RS13525	ENOG4109045	doxx family
ALEK_RS13530	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
ALEK_RS13540	ENOG4109045	doxx family
ALEK_RS13555	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
ALEK_RS13585	ENOG4105DC1	bifunctional purine biosynthesis protein purh
ALEK_RS13615	ENOG4108BGM	Quinol dehydrogenase periplasmic component
ALEK_RS13625	ENOG4106RE7	Cytochrome
ALEK_RS13635	ENOG4108M15	ABC transporter
ALEK_RS13645	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
ALEK_RS13650	ENOG4105DR5	peptidase
ALEK_RS13655	ENOG4105CJW	magnesium transporter
ALEK_RS13665	ENOG4105EUJ	GTP cyclohydrolase i
ALEK_RS13675	ENOG4107QHF	type ii secretion system protein e
ALEK_RS13690	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
ALEK_RS13695	ENOG4105C0P	Mg chelatase subunit ChlI
ALEK_RS13700	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS13705	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_RS13715	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ALEK_RS13720	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ALEK_RS13725	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
ALEK_RS13730	ENOG4107QVM	von Willebrand factor, type A
ALEK_RS13735	ENOG4105CSR	polyphosphate kinase 2
ALEK_RS13740	ENOG4105CSR	polyphosphate kinase 2
ALEK_RS13750	ENOG4105VCQ	rubredoxin
ALEK_RS13835	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS13840	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_RS13880	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ALEK_RS13930	ENOG4105CE1	Ferrous iron transport protein b
ALEK_RS13965	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
ALEK_RS13975	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
ALEK_RS13980	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ALEK_RS13985	ENOG4105F4G	Membrane
ALEK_RS14000	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
ALEK_RS14015	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_RS14030	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ALEK_RS14040	ENOG4105I03	Flagellin
ALEK_RS14045	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ALEK_RS14050	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
ALEK_RS14055	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ALEK_RS14065	ENOG4105CEY	Amp-dependent synthetase and ligase
ALEK_RS14070	ENOG4105DJG	MaoC domain protein dehydratase
ALEK_RS14110	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS14120	ENOG4107XC4	flavin reductase domain protein, FMN-binding
ALEK_RS14155	ENOG4105D7B	Flagellar biosynthesis protein flha
ALEK_RS14160	ENOG4105DTJ	flagellar hook-associated protein
ALEK_RS14165	ENOG4108JIR	Flagellum-specific ATP synthase
ALEK_RS14175	ENOG4105D00	flagellar biosynthetic protein flhB
ALEK_RS14190	ENOG4108ZC9	flagellar basal-body rod protein flgc
ALEK_RS14195	ENOG41084DA	flagellar hook-basal body complex protein fliE
ALEK_RS14205	ENOG4107R21	site-determining protein
ALEK_RS14210	ENOG4105FZW	flagellar biosynthesis regulator FlhF
ALEK_RS14225	ENOG4105YKR	
ALEK_RS14235	ENOG4105E14	MotA TolQ exbB proton channel
ALEK_RS14240	ENOG4105DD5	Flagellar motor switch protein
ALEK_RS14260	ENOG4105BZE	flagellar hook protein, FlgE
ALEK_RS14265	ENOG4105BZE	flagellar hook protein, FlgE
ALEK_RS14285	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
ALEK_RS14290	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
ALEK_RS14295	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
ALEK_RS14300	ENOG4105CGA	flagellar basal-body rod protein FlgG
ALEK_RS14310	ENOG4108VYJ	response regulator receiver protein
ALEK_RS14315	ENOG4105CGA	flagellar basal-body rod protein FlgG
ALEK_RS14330	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
ALEK_RS14340	ENOG4105K5M	30s ribosomal protein S16
ALEK_RS14345	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALEK_RS14350	ENOG4105C34	Pseudouridine synthase
ALEK_RS14355	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
ALEK_RS14365	ENOG4105EGD	dinuclear metal center protein, YbgI family
ALEK_RS14370	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
ALEK_RS14375	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
ALEK_RS14385	ENOG4105CFP	Peptidase U32
ALEK_RS14430	ENOG4105QN4	diheme cytochrome
ALEK_RS14455	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
ALEK_RS14460	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ALEK_RS14465	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
ALEK_RS14470	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ALEK_RS14475	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ALEK_RS14480	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ALEK_RS14490	ENOG4105DUM	transcriptional regulator, lysR family
ALEK_RS14500	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ALEK_RS14510	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_RS14515	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
ALEK_RS14520	ENOG4105KME	endoribonuclease L-psp
ALEK_RS14525	ENOG4105HMI	Membrane
ALEK_RS14530	ENOG4108UPT	UPF0178 protein
ALEK_RS14550	ENOG4107R4J	Chloride channel
ALEK_RS14560	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS14575	ENOG4105BZU	Histidine kinase
ALEK_RS14585	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ALEK_RS14590	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ALEK_RS14600	ENOG4108VZM	50s ribosomal protein L10
ALEK_RS14605	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
ALEK_RS14610	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
ALEK_RS14615	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
ALEK_RS14630	ENOG41086AR	50S ribosomal protein L33
ALEK_RS14635	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ALEK_RS14665	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ALEK_RS14670	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ALEK_RS14680	ENOG4108JQC	penicillin-binding protein 1A
ALEK_RS14685	ENOG4105C5F	glutamine synthetase
ALEK_RS14695	ENOG4108ZEX	molybdopterin converting factor, subunit 2
ALEK_RS14705	ENOG4108XUR	Pfam:DUF178
ALEK_RS14710	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ALEK_RS14720	ENOG4105CNI	cell division protein FtsW
ALEK_RS14725	ENOG4105CJN	penicillin-binding protein
ALEK_RS14730	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ALEK_RS14775	ENOG4105DDQ	anthranilate synthase
ALEK_RS14795	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ALEK_RS14800	ENOG4105BZU	Histidine kinase
ALEK_RS14805	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ALEK_RS14810	ENOG4105C87	Aminotransferase class I and II
ALEK_RS14815	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ALEK_RS14820	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_RS14825	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_RS14830	ENOG4105GKE	subunit e
ALEK_RS14840	ENOG4105BZN	citrate synthase
ALEK_RS14845	ENOG4108IEH	NADH dehydrogenase subunit g
ALEK_RS14850	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ALEK_RS14860	ENOG4107UFS	subunit j
ALEK_RS14865	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_RS14870	ENOG4105D65	subunit l
ALEK_RS14875	ENOG4105C8S	subunit m
ALEK_RS14880	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_RS14885	ENOG4108S24	Fumarate reduCtase
ALEK_RS14890	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
ALEK_RS14895	ENOG4105E33	succinate dehydrogenase
ALEK_RS14910	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ALEK_RS14915	ENOG4108VKG	metal-dependent hydrolase
ALEK_RS14975	ENOG41081FY	multiple antibiotic resistance (MarC)-related
ALEK_RS14980	ENOG4105E5Q	amino acid AbC transporter
ALEK_RS14985	ENOG4106PMH	Extracellular solute-binding protein family 3
ALEK_RS14990	ENOG4106PMH	Extracellular solute-binding protein family 3
ALEK_RS15010	ENOG4108BSC	Methyltransferase
ALEK_RS15015	ENOG4105YVS	arsR family transcriptional regulator
ALEK_RS15025	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
ALEK_RS15030	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
ALEK_RS15060	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ALEK_RS15070	ENOG4105C5I	Dehydrogenase
ALEK_RS15095	ENOG4105CR4	methylisocitrate lyase
ALEK_RS15100	ENOG4105BZN	citrate synthase
ALEK_RS15105	ENOG4108I0Z	Aconitate hydratase
ALEK_RS15110	ENOG4105C7F	AcnD-accessory protein PrpF
ALEK_RS15115	ENOG410620I	Diguanylate cyclase
ALEK_RS15125	ENOG4108QGH	periplasmic
ALEK_RS15135	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
ALEK_RS15150	ENOG4107QMP	dna polymerase iii subunits gamma and tau
ALEK_RS15155	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
ALEK_RS15170	ENOG4105D01	(LipO)protein
ALEK_RS15175	ENOG4108UMI	ABC transporter, permease
ALEK_RS15180	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
ALEK_RS15185	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
ALEK_RS15190	ENOG4105D3R	alkyl hydroperoxide reductase
ALEK_RS15200	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ALEK_RS15210	ENOG4105YQ2	50s ribosomal protein l32
ALEK_RS15215	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
ALEK_RS15220	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ALEK_RS15230	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_RS15235	ENOG4108YYC	ycei family
ALEK_RS15250	ENOG4108UMN	azlc family
ALEK_RS15280	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ALEK_RS15295	ENOG4105CXT	aspartate transcarbamylase
ALEK_RS15305	ENOG4105C8Y	Acetylornithine aminotransferase
ALEK_RS15315	ENOG4105BZU	Histidine kinase
ALEK_RS15345	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ALEK_RS15350	ENOG41082UM	UPF0102 protein
ALEK_RS15355	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
ALEK_RS15365	ENOG4106AXJ	AraC family transcriptional regulator
ALEK_RS15370	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ALEK_RS15390	ENOG4105DVY	radical SAM domain protein
ALEK_RS15400	ENOG4105KB8	(LipO)protein
ALEK_RS15405	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ALEK_RS15415	ENOG4105CHV	Transcription elongation factor NusA
ALEK_RS15420	ENOG4105C8N	cysteinyl-tRNA synthetase
ALEK_RS15435	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
ALEK_RS15440	ENOG4108UUM	single-stranded DNA-binding protein
ALEK_RS15445	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
ALEK_RS15455	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
ALEK_RS15470	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
ALEK_RS15490	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
ALEK_RS15510	ENOG4106AXJ	AraC family transcriptional regulator
ALEK_RS15515	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ALEK_RS15520	ENOG4105DFU	Cell wall formation (By similarity)
ALEK_RS15530	ENOG4105CHM	Aminotransferase
ALEK_RS15550	ENOG4105BZU	Histidine kinase
ALEK_RS15555	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
ALEK_RS15585	ENOG4108EHY	type IV secretion system
ALEK_RS15620	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ALEK_RS15630	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
ALEK_RS15640	ENOG4105EAC	phosphoserine phosphatase
ALEK_RS15645	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
ALEK_RS15655	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS15660	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
ALEK_RS15670	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
ALEK_RS15680	ENOG4108YYC	ycei family
ALEK_RS15685	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ALEK_RS15705	ENOG4107TPX	flagellar hook-associated
ALEK_RS15740	ENOG4105VS8	Flagellar biosynthetic protein fliq
ALEK_RS15750	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
ALEK_RS15755	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
ALEK_RS15760	ENOG4105EKE	dihydroorotase
ALEK_RS15765	ENOG4108YZA	Nitrogen regulatory protein pii
ALEK_RS15775	ENOG4108YZA	Nitrogen regulatory protein pii
ALEK_RS15785	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS15790	ENOG4107XTP	(EAL) domain protein
ALEK_RS15795	ENOG4105D7T	ABC transporter
ALEK_RS15815	ENOG4105D9P	serine threonine protein kinase
ALEK_RS15830	ENOG4108XIB	electron transport protein ysaA
ALEK_RS15855	ENOG41067MG	lrgb family
ALEK_RS15860	ENOG4105VAW	lrga family
ALEK_RS15865	ENOG4108IFG	nitrite reductase, (NAD(P)H)
ALEK_RS15900	ENOG4105CEY	Amp-dependent synthetase and ligase
ALEK_RS15910	ENOG4105FR1	rard protein
ALEK_RS15915	ENOG4105BZU	Histidine kinase
ALEK_RS15930	ENOG4108UXE	Protein tyrosine phosphatase
ALEK_RS15935	ENOG4108MGY	Histidine kinase
ALEK_RS15940	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
ALEK_RS15945	ENOG4107R5R	arsenical pump membrane protein
ALEK_RS15955	ENOG41085FC	arsR family transcriptional regulator
ALEK_RS15960	ENOG4108RPX	mosc domain containing protein
ALEK_RS15965	ENOG41067MG	lrgb family
ALEK_RS15975	ENOG4108SGR	YheO domain-containing protein
ALEK_RS15985	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
ALEK_RS16000	ENOG4105CV1	Transketolase (EC 2.2.1.1)
ALEK_RS16005	ENOG4105BZU	Histidine kinase
ALEK_RS16020	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
ALEK_RS16035	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS16070	ENOG4105C01	Dihydroxy-acid dehydratase
ALEK_RS16075	ENOG4105C0H	protease
ALEK_RS16095	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
ALEK_RS16100	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
ALEK_RS16105	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_RS16130	ENOG4105BZU	Histidine kinase
ALEK_RS16140	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
ALEK_RS16155	ENOG41081FY	multiple antibiotic resistance (MarC)-related
ALEK_RS16160	ENOG4108K7V	UPF0284 protein
ALEK_RS16170	ENOG4105K63	Thioredoxin
ALEK_RS16175	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
ALEK_RS16185	ENOG4105BZU	Histidine kinase
ALEK_RS16190	ENOG4105DJ4	phosphatidylserine decarboxylase
ALEK_RS16200	ENOG4105CA3	membrane-bound lytic murein transglycosylase
ALEK_RS16210	ENOG4105CFG	Acts as a chaperone (By similarity)
ALEK_RS16215	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALEK_RS16225	ENOG4105H1G	trap transporter solute receptor taxi family
ALEK_RS16235	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_RS16245	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ALEK_RS16255	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
ALEK_RS16260	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ALEK_RS16270	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ALEK_RS16280	ENOG4105C1J	atp-dependent rna helicase
ALEK_RS16285	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ALEK_RS16290	ENOG4105I03	Flagellin
ALEK_RS16295	ENOG4105I03	Flagellin
ALEK_RS16300	ENOG4105I03	Flagellin
ALEK_RS16305	ENOG4105I03	Flagellin
ALEK_RS16310	ENOG4105I03	Flagellin
ALEK_RS16315	ENOG4105I03	Flagellin
ALEK_RS16320	ENOG4105I03	Flagellin
ALEK_RS16325	ENOG4105I03	Flagellin
ALEK_RS16330	ENOG4105I03	Flagellin
ALEK_RS16335	ENOG4105I03	Flagellin
ALEK_RS16340	ENOG4105I03	Flagellin
ALEK_RS16345	ENOG4105I03	Flagellin
ALEK_RS16375	ENOG4107TY6	Acylneuraminate cytidylyltransferase
ALEK_RS16385	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
ALEK_RS16395	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ALEK_RS16405	ENOG4105D2T	synthase
ALEK_RS16415	ENOG4105C5E	polysaccharide biosynthesis protein
ALEK_RS16425	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ALEK_RS16430	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ALEK_RS16450	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
ALEK_RS16465	ENOG4105D4A	Cell wall formation (By similarity)
ALEK_RS16470	ENOG4105E63	Pfam:DUF178
ALEK_RS16480	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_RS16485	ENOG4105C8S	subunit m
ALEK_RS16490	ENOG4105D65	subunit l
ALEK_RS16495	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_RS16505	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_RS16510	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ALEK_RS16515	ENOG4108IEH	NADH dehydrogenase subunit g
ALEK_RS16530	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_RS16535	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ALEK_RS16540	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_RS16545	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ALEK_RS16550	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS16595	ENOG4105DZR	Type I site-specific deoxyribonuclease
ALEK_RS16640	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
ALEK_RS16650	ENOG4105BZU	Histidine kinase
ALEK_RS16655	ENOG4108PYU	two-component system response regulator
ALEK_RS16670	ENOG4105BZU	Histidine kinase
ALEK_RS16685	ENOG4105WPN	DNA integration recombination invertion protein
ALEK_RS16690	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALEK_RS16695	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ALEK_RS16700	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALEK_RS16705	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
ALEK_RS16725	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_RS16730	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
ALEK_RS16740	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ALEK_RS16745	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ALEK_RS16750	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
ALEK_RS16775	ENOG4105F8J	Adenylate Guanylate cyclase
ALEK_RS16790	ENOG4105C0B	DNA polymerase III (alpha subunit)
ALEK_RS16795	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ALEK_RS16820	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ALEK_RS16865	ENOG4105HFZ	Membrane
ALEK_RS16870	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ALEK_RS16880	ENOG4105NU9	Preprotein translocase subunit SecG
ALEK_RS16890	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ALEK_RS16895	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ALEK_RS16905	ENOG4105D8G	Major Facilitator superfamily
ALEK_RS16910	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_RS16915	ENOG4105BZU	Histidine kinase
ALEK_RS16920	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
ALEK_RS16925	ENOG410802Z	Protein of unknown function (DUF328)
ALEK_RS16960	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
ALEK_RS16965	ENOG4105C26	Dehydrogenase
ALEK_RS16970	ENOG4105C7K	acetolactate synthase
ALEK_RS16975	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ALEK_RS17030	ENOG4105CBX	hi0933 family
ALEK_RS17035	ENOG4108RPX	mosc domain containing protein
ALEK_RS17065	ENOG4105C6T	cysteine synthase
ALEK_RS17075	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
ALEK_RS17080	ENOG4105C11	sulfate adenylyltransferase), subunit 2
ALEK_RS17085	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
ALEK_RS17090	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
ALEK_RS17100	ENOG4105DIN	metallophosphoesterase
ALEK_RS17110	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ALEK_RS17115	ENOG4105CI3	gtp-binding protein typa
ALEK_RS17120	ENOG4105CSV	Glutaminase
ALEK_RS17130	ENOG4105GAV	receptor
ALEK_RS17140	ENOG4105EMN	RNA polymerase sigma factor
ALEK_RS17150	ENOG4105EN6	Membrane
ALEK_RS17165	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
ALEK_RS17170	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)