locus-tag	class	description
AMRN_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMRN_RS00010	COG0592	DNA-directed DNA polymerase activity
AMRN_RS00015	COG0187	DNA topoisomerase II activity
AMRN_RS00045	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMRN_RS00060	COG1238	metal cluster binding
AMRN_RS00065	COG2202	Pas domain
AMRN_RS00065	COG2205	protein histidine kinase activity
AMRN_RS00070	COG0564	pseudouridine synthase activity
AMRN_RS00075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMRN_RS00080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMRN_RS00085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMRN_RS00095	COG0778	Nitroreductase
AMRN_RS00100	COG2205	protein histidine kinase activity
AMRN_RS00105	COG1151	hydroxylamine reductase activity
AMRN_RS00110	COG0493	'glutamate synthase
AMRN_RS00130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMRN_RS00145	COG1858	cytochrome C peroxidase
AMRN_RS00155	COG2207	Transcriptional regulator
AMRN_RS00155	COG4753	response regulator
AMRN_RS00160	COG3852	Histidine kinase
AMRN_RS00170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMRN_RS00175	COG0348	domain, Protein
AMRN_RS00180	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMRN_RS00185	COG3118	belongs to the thioredoxin family
AMRN_RS00190	COG1733	regulation of RNA biosynthetic process
AMRN_RS00195	COG0604	alcohol dehydrogenase
AMRN_RS00200	COG1733	regulation of RNA biosynthetic process
AMRN_RS00205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMRN_RS00210	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMRN_RS00225	COG0107	imidazoleglycerol-phosphate synthase activity
AMRN_RS00230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMRN_RS00235	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AMRN_RS00240	COG0517	IMP dehydrogenase activity
AMRN_RS00240	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AMRN_RS00245	COG1187	pseudouridine synthase activity
AMRN_RS00250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMRN_RS00250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AMRN_RS00255	COG1981	membrane
AMRN_RS00260	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMRN_RS00265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMRN_RS00275	COG0840	transmembrane signaling receptor activity
AMRN_RS00280	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AMRN_RS00285	COG0778	Nitroreductase
AMRN_RS00295	COG0367	asparagine synthase
AMRN_RS00305	COG0306	phosphate transporter
AMRN_RS00315	COG0513	Belongs to the DEAD box helicase family
AMRN_RS00320	COG0439	Biotin carboxylase
AMRN_RS00325	COG0511	ligase activity, forming carbon-carbon bonds
AMRN_RS00340	COG0247	lactate metabolic process
AMRN_RS00345	COG1139	Iron-sulfur cluster binding protein
AMRN_RS00350	COG1556	Lactate utilization protein
AMRN_RS00355	COG3852	Histidine kinase
AMRN_RS00360	COG0745	RESPONSE REGULATOR receiver
AMRN_RS00365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AMRN_RS00380	COG0277	FAD linked oxidase domain protein
AMRN_RS00380	COG0247	lactate metabolic process
AMRN_RS00390	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMRN_RS00395	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMRN_RS00405	COG0745	RESPONSE REGULATOR receiver
AMRN_RS00420	COG1342	Belongs to the UPF0251 family
AMRN_RS00450	COG0390	transport system, permease component
AMRN_RS00455	COG0745	RESPONSE REGULATOR receiver
AMRN_RS00465	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMRN_RS00470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMRN_RS00485	COG0642	Histidine kinase
AMRN_RS00490	COG0745	RESPONSE REGULATOR receiver
AMRN_RS00505	COG3220	belongs to the UPF0276 family
AMRN_RS00515	COG4191	Histidine kinase
AMRN_RS00535	COG0534	Mate efflux family protein
AMRN_RS00540	COG0789	Transcriptional regulator
AMRN_RS00545	COG1335	isochorismatase
AMRN_RS00550	COG0460	homoserine dehydrogenase
AMRN_RS00555	COG0436	Aminotransferase
AMRN_RS00570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AMRN_RS00575	COG0254	rRNA binding
AMRN_RS00580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMRN_RS00595	COG2199	diguanylate cyclase activity
AMRN_RS00635	COG2239	Acts as a magnesium transporter
AMRN_RS00640	COG2203	Gaf domain
AMRN_RS00640	COG5001	Diguanylate cyclase
AMRN_RS00640	COG3706	GGDEF domain
AMRN_RS00640	COG4251	negative regulation of phosphorylation
AMRN_RS00655	COG0492	ferredoxin-NADP+ reductase activity
AMRN_RS00660	COG0450	alkyl hydroperoxide reductase
AMRN_RS00670	COG4191	Histidine kinase
AMRN_RS00685	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AMRN_RS00690	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMRN_RS00695	COG0237	dephospho-CoA kinase activity
AMRN_RS00700	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AMRN_RS00705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMRN_RS00715	COG2353	YceI-like domain
AMRN_RS00720	COG1846	Transcriptional regulator
AMRN_RS00725	COG1280	lysine exporter protein (LysE YggA)
AMRN_RS00735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMRN_RS00740	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AMRN_RS00745	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMRN_RS00755	COG0505	Belongs to the CarA family
AMRN_RS00770	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMRN_RS00770	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMRN_RS00780	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMRN_RS00785	COG0489	protein tyrosine kinase activity
AMRN_RS00795	COG0140	phosphoribosyl-ATP diphosphatase activity
AMRN_RS00795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMRN_RS00815	COG1410	methionine synthase
AMRN_RS00815	COG0646	methionine synthase
AMRN_RS00850	COG5001	Diguanylate cyclase
AMRN_RS00850	COG4251	negative regulation of phosphorylation
AMRN_RS00850	COG2203	Gaf domain
AMRN_RS00850	COG3706	GGDEF domain
AMRN_RS00860	COG0277	FAD linked oxidase domain protein
AMRN_RS00870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMRN_RS00875	COG2226	methyltransferase
AMRN_RS00880	COG0196	riboflavin kinase activity
AMRN_RS00890	COG1739	Uncharacterized protein family UPF0029
AMRN_RS00895	COG1450	Type ii and iii secretion system protein
AMRN_RS00910	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMRN_RS00920	COG0069	glutamate synthase activity
AMRN_RS00940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMRN_RS00945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMRN_RS00950	COG0284	orotidine-5'-phosphate decarboxylase activity
AMRN_RS01040	COG1854	S-ribosylhomocysteine lyase activity
AMRN_RS01045	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMRN_RS01045	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMRN_RS01045	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMRN_RS01045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMRN_RS01050	COG0546	phosphoglycolate phosphatase activity
AMRN_RS01055	COG0747	negative chemotaxis
AMRN_RS01075	COG0243	molybdopterin cofactor binding
AMRN_RS01085	COG3708	Transcriptional regulator
AMRN_RS01085	COG2207	Transcriptional regulator
AMRN_RS01090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMRN_RS01095	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMRN_RS01100	COG2205	protein histidine kinase activity
AMRN_RS01115	COG0704	Plays a role in the regulation of phosphate uptake
AMRN_RS01120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMRN_RS01130	COG0573	inorganic phosphate transmembrane transporter activity
AMRN_RS01135	COG2199	diguanylate cyclase activity
AMRN_RS01135	COG2203	Gaf domain
AMRN_RS01135	COG2200	EAL domain
AMRN_RS01145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMRN_RS01150	COG0268	Binds directly to 16S ribosomal RNA
AMRN_RS01155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMRN_RS01160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMRN_RS01165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMRN_RS01170	COG0746	molybdenum cofactor guanylyltransferase activity
AMRN_RS01185	COG0243	molybdopterin cofactor binding
AMRN_RS01190	COG0437	4 iron, 4 sulfur cluster binding
AMRN_RS01200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMRN_RS01210	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMRN_RS01215	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMRN_RS01220	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMRN_RS01255	COG0575	Belongs to the CDS family
AMRN_RS01260	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMRN_RS01280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMRN_RS01285	COG0023	Translation Initiation Factor
AMRN_RS01290	COG1115	amino acid carrier protein
AMRN_RS01295	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMRN_RS01295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMRN_RS01305	COG2022	thiamine diphosphate biosynthetic process
AMRN_RS01375	COG0745	RESPONSE REGULATOR receiver
AMRN_RS01380	COG4251	negative regulation of phosphorylation
AMRN_RS01380	COG3706	GGDEF domain
AMRN_RS01380	COG5001	Diguanylate cyclase
AMRN_RS01380	COG2203	Gaf domain
AMRN_RS01385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMRN_RS01390	COG0585	pseudouridine synthase activity
AMRN_RS01400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMRN_RS01405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMRN_RS01410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMRN_RS01425	COG0793	Belongs to the peptidase S41A family
AMRN_RS01430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMRN_RS01435	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMRN_RS01440	COG0047	phosphoribosylformylglycinamidine synthase activity
AMRN_RS01450	COG0204	Acyl-transferase
AMRN_RS01455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMRN_RS01465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMRN_RS01470	COG0018	arginyl-trna synthetase
AMRN_RS01480	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMRN_RS01485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMRN_RS01490	COG0126	phosphoglycerate kinase activity
AMRN_RS01495	COG0149	triose-phosphate isomerase activity
AMRN_RS01500	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMRN_RS01505	COG0019	diaminopimelate decarboxylase activity
AMRN_RS01510	COG0647	UMP catabolic process
AMRN_RS01515	COG0077	Prephenate dehydratase
AMRN_RS01515	COG1605	Chorismate mutase
AMRN_RS01520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMRN_RS01525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMRN_RS01530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMRN_RS01540	COG0424	maF-like protein
AMRN_RS01565	COG0791	NLP P60 protein
AMRN_RS01575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMRN_RS01580	COG3118	belongs to the thioredoxin family
AMRN_RS01585	COG5002	protein histidine kinase activity
AMRN_RS01590	COG0745	RESPONSE REGULATOR receiver
AMRN_RS01595	COG1115	amino acid carrier protein
AMRN_RS01600	COG0492	ferredoxin-NADP+ reductase activity
AMRN_RS01605	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMRN_RS01610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AMRN_RS01615	COG1242	4 iron, 4 sulfur cluster binding
AMRN_RS01625	COG0210	DNA helicase
AMRN_RS01630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMRN_RS01635	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMRN_RS01640	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMRN_RS01645	COG3278	Belongs to the heme-copper respiratory oxidase family
AMRN_RS01680	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AMRN_RS01685	COG0814	amino acid
AMRN_RS01690	COG4773	Receptor
AMRN_RS01695	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMRN_RS01705	COG4773	Receptor
AMRN_RS01715	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMRN_RS01725	COG0157	Belongs to the NadC ModD family
AMRN_RS01740	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AMRN_RS01750	COG0083	homoserine kinase activity
AMRN_RS01760	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMRN_RS01765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMRN_RS01770	COG0779	Required for maturation of 30S ribosomal subunits
AMRN_RS01775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMRN_RS01775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMRN_RS01830	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMRN_RS01835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMRN_RS01840	COG1185	polyribonucleotide nucleotidyltransferase activity
AMRN_RS01840	COG0539	negative regulation of cytoplasmic translation
AMRN_RS01845	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMRN_RS01850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMRN_RS01855	COG0072	phenylalanine-tRNA ligase activity
AMRN_RS01855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMRN_RS01860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMRN_RS01865	COG0537	adenosine 5'-monophosphoramidase activity
AMRN_RS01870	COG0825	malonyl-CoA metabolic process
AMRN_RS01875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMRN_RS01880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMRN_RS01900	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AMRN_RS01905	COG0303	'Molybdopterin
AMRN_RS01915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMRN_RS01930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMRN_RS01940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMRN_RS01945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMRN_RS01950	COG3706	GGDEF domain
AMRN_RS01955	COG1074	ATP-dependent DNA helicase activity
AMRN_RS01960	COG0840	transmembrane signaling receptor activity
AMRN_RS01965	COG0352	thiamine-phosphate diphosphorylase activity
AMRN_RS01970	COG0840	transmembrane signaling receptor activity
AMRN_RS01975	COG0356	it plays a direct role in the translocation of protons across the membrane
AMRN_RS01980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMRN_RS01985	COG0336	Belongs to the RNA methyltransferase TrmD family
AMRN_RS01990	COG0335	large ribosomal subunit rRNA binding
AMRN_RS02005	COG1280	lysine exporter protein (LysE YggA)
AMRN_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
AMRN_RS02025	COG2966	Psort location CytoplasmicMembrane, score
AMRN_RS02040	COG3287	FIST C domain
AMRN_RS02040	COG2200	EAL domain
AMRN_RS02040	COG2199	diguanylate cyclase activity
AMRN_RS02050	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AMRN_RS02055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMRN_RS02110	COG1971	Probably functions as a manganese efflux pump
AMRN_RS02120	COG2814	Major facilitator Superfamily
AMRN_RS02125	COG1132	(ABC) transporter
AMRN_RS02130	COG1132	(ABC) transporter
AMRN_RS02135	COG4771	TonB-dependent receptor
AMRN_RS02145	COG4771	TonB-dependent receptor
AMRN_RS02155	COG4771	TonB-dependent receptor
AMRN_RS02165	COG1629	transport
AMRN_RS02170	COG0784	Response regulator, receiver
AMRN_RS02205	COG0848	biopolymer transport protein
AMRN_RS02210	COG0811	peptide transport
AMRN_RS02215	COG0811	peptide transport
AMRN_RS02250	COG4774	siderophore transport
AMRN_RS02255	COG1917	Cupin 2, conserved barrel domain protein
AMRN_RS02255	COG2169	Transcriptional regulator
AMRN_RS02265	COG4773	Receptor
AMRN_RS02270	COG2207	Transcriptional regulator
AMRN_RS02270	COG4753	response regulator
AMRN_RS02275	COG3852	Histidine kinase
AMRN_RS02295	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMRN_RS02300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMRN_RS02300	COG1333	cytochrome c biogenesis protein
AMRN_RS02305	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AMRN_RS02310	COG3005	denitrification pathway
AMRN_RS02320	COG0840	transmembrane signaling receptor activity
AMRN_RS02340	COG3043	anaerobic respiration
AMRN_RS02345	COG0348	domain, Protein
AMRN_RS02350	COG0437	4 iron, 4 sulfur cluster binding
AMRN_RS02355	COG0243	molybdopterin cofactor binding
AMRN_RS02360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMRN_RS02360	COG1648	precorrin-2 dehydrogenase activity
AMRN_RS02385	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMRN_RS02395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMRN_RS02405	COG2404	hydrolase activity, acting on ester bonds
AMRN_RS02415	COG0579	oxidoreductase
AMRN_RS02430	COG0745	RESPONSE REGULATOR receiver
AMRN_RS02445	COG0753	catalase activity
AMRN_RS02470	COG0642	Histidine kinase
AMRN_RS02475	COG0745	RESPONSE REGULATOR receiver
AMRN_RS02480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMRN_RS02485	COG0191	fructose-bisphosphate aldolase activity
AMRN_RS02490	COG0848	biopolymer transport protein
AMRN_RS02495	COG0811	peptide transport
AMRN_RS02510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMRN_RS02515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMRN_RS02525	COG0142	geranyltranstransferase activity
AMRN_RS02530	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMRN_RS02535	COG0442	prolyl-tRNA aminoacylation
AMRN_RS02540	COG0668	transmembrane transport
AMRN_RS02545	COG0617	tRNA 3'-terminal CCA addition
AMRN_RS02560	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMRN_RS02565	COG1862	Preprotein translocase
AMRN_RS02570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMRN_RS02575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMRN_RS02595	COG0495	leucyl-tRNA aminoacylation
AMRN_RS02605	COG0285	dihydrofolate synthase activity
AMRN_RS02610	COG0739	heme binding
AMRN_RS02640	COG1136	(ABC) transporter
AMRN_RS02640	COG0577	efflux transmembrane transporter activity
AMRN_RS02645	COG0577	efflux transmembrane transporter activity
AMRN_RS02645	COG1136	(ABC) transporter
AMRN_RS02650	COG4771	TonB-dependent receptor
AMRN_RS02670	COG0784	Response regulator, receiver
AMRN_RS02695	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMRN_RS02700	COG2986	histidine ammonia-lyase
AMRN_RS02715	COG1053	succinate dehydrogenase
AMRN_RS02715	COG3976	FMN-binding domain protein
AMRN_RS02720	COG3852	Histidine kinase
AMRN_RS02725	COG0745	RESPONSE REGULATOR receiver
AMRN_RS02735	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMRN_RS02745	COG0745	RESPONSE REGULATOR receiver
AMRN_RS02750	COG0642	Histidine kinase
AMRN_RS02755	COG2081	HI0933 family
AMRN_RS02760	COG1692	metallophosphoesterase
AMRN_RS02780	COG2226	methyltransferase
AMRN_RS02785	COG1570	exodeoxyribonuclease VII activity
AMRN_RS02795	COG0840	transmembrane signaling receptor activity
AMRN_RS02800	COG0835	chemotaxis
AMRN_RS02805	COG0745	RESPONSE REGULATOR receiver
AMRN_RS02810	COG2204	response regulator
AMRN_RS02815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMRN_RS02825	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMRN_RS02830	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMRN_RS02845	COG0459	protein refolding
AMRN_RS02865	COG2076	Multidrug Resistance protein
AMRN_RS02880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMRN_RS02885	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMRN_RS02890	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AMRN_RS02900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMRN_RS02915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMRN_RS02920	COG2264	protein methyltransferase activity
AMRN_RS02925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMRN_RS02935	COG0784	Response regulator, receiver
AMRN_RS02935	COG3437	response regulator, receiver
AMRN_RS02950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMRN_RS02955	COG0475	glutathione-regulated potassium exporter activity
AMRN_RS02955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMRN_RS02975	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMRN_RS03010	COG1309	transcriptional regulator
AMRN_RS03015	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMRN_RS03025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMRN_RS03030	COG1090	epimerase
AMRN_RS03035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMRN_RS03055	COG0481	GTPase activity
AMRN_RS03065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMRN_RS03070	COG0482	sulfurtransferase activity
AMRN_RS03075	COG0482	sulfurtransferase activity
AMRN_RS03080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMRN_RS03085	COG0006	proline dipeptidase activity
AMRN_RS03090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMRN_RS03095	COG0402	S-adenosylhomocysteine deaminase activity
AMRN_RS03100	COG0616	signal peptide processing
AMRN_RS03105	COG0513	Belongs to the DEAD box helicase family
AMRN_RS03110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMRN_RS03115	COG0280	phosphate acetyltransferase
AMRN_RS03120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMRN_RS03125	COG2176	DNA-directed DNA polymerase activity
AMRN_RS03145	COG2176	DNA-directed DNA polymerase activity
AMRN_RS03155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMRN_RS03165	COG0745	RESPONSE REGULATOR receiver
AMRN_RS03170	COG0642	Histidine kinase
AMRN_RS03240	COG0579	oxidoreductase
AMRN_RS03245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMRN_RS03260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMRN_RS03285	COG0714	Associated with various cellular activities
AMRN_RS03295	COG0052	Belongs to the universal ribosomal protein uS2 family
AMRN_RS03300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMRN_RS03305	COG1136	(ABC) transporter
AMRN_RS03315	COG0194	GDP metabolic process
AMRN_RS03320	COG5002	protein histidine kinase activity
AMRN_RS03320	COG5001	Diguanylate cyclase
AMRN_RS03330	COG2217	Heavy metal translocating P-type atpase
AMRN_RS03340	COG2863	cytochrome
AMRN_RS03345	COG1132	(ABC) transporter
AMRN_RS03350	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMRN_RS03360	COG0784	Response regulator, receiver
AMRN_RS03360	COG3437	response regulator, receiver
AMRN_RS03365	COG1355	regulation of microtubule-based process
AMRN_RS03370	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AMRN_RS03375	COG1121	(ABC) transporter
AMRN_RS03380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMRN_RS03385	COG2996	Protein conserved in bacteria
AMRN_RS03390	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AMRN_RS03400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMRN_RS03405	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AMRN_RS03410	COG0300	oxidoreductase activity
AMRN_RS03440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMRN_RS03450	COG0210	DNA helicase
AMRN_RS03455	COG2199	diguanylate cyclase activity
AMRN_RS03460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMRN_RS03530	COG0525	valine-tRNA ligase activity
AMRN_RS03535	COG1733	regulation of RNA biosynthetic process
AMRN_RS03560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMRN_RS03580	COG2814	Major facilitator Superfamily
AMRN_RS03585	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMRN_RS03605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMRN_RS03610	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMRN_RS03615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMRN_RS03630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMRN_RS03645	COG0840	transmembrane signaling receptor activity
AMRN_RS03655	COG2217	Heavy metal translocating P-type atpase
AMRN_RS03690	COG0582	viral genome integration into host DNA
AMRN_RS03700	COG0863	Belongs to the N(4) N(6)-methyltransferase family
AMRN_RS03795	COG0450	alkyl hydroperoxide reductase
AMRN_RS03800	COG2354	Protein conserved in bacteria
AMRN_RS03810	COG1124	(ABC) transporter
AMRN_RS03815	COG0444	Belongs to the ABC transporter superfamily
AMRN_RS03825	COG0601	transmembrane transport
AMRN_RS03845	COG0840	transmembrane signaling receptor activity
AMRN_RS03850	COG0840	transmembrane signaling receptor activity
AMRN_RS03855	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMRN_RS03885	COG1858	cytochrome C peroxidase
AMRN_RS03890	COG1028	Short-chain dehydrogenase reductase Sdr
AMRN_RS03910	COG2207	Transcriptional regulator
AMRN_RS03910	COG1917	Cupin 2, conserved barrel domain protein
AMRN_RS03920	COG0803	Belongs to the bacterial solute-binding protein 9 family
AMRN_RS03925	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AMRN_RS03950	COG0626	cystathionine gamma-synthase activity
AMRN_RS03955	COG1242	4 iron, 4 sulfur cluster binding
AMRN_RS03960	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AMRN_RS04005	COG2151	metal-sulfur cluster biosynthetic enzyme
AMRN_RS04010	COG2166	iron-sulfur cluster assembly
AMRN_RS04015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMRN_RS04020	COG0719	Fe-S assembly protein
AMRN_RS04025	COG0396	ATPase activity
AMRN_RS04030	COG0719	Fe-S assembly protein
AMRN_RS04035	COG0765	amino acid transport
AMRN_RS04040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMRN_RS04050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AMRN_RS04050	COG0822	iron-sulfur transferase activity
AMRN_RS04050	COG2906	2 iron, 2 sulfur cluster binding
AMRN_RS04070	COG0165	Argininosuccinate lyase
AMRN_RS04075	COG0835	chemotaxis
AMRN_RS04075	COG0784	Response regulator, receiver
AMRN_RS04080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AMRN_RS04085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMRN_RS04090	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMRN_RS04105	COG0556	nucleotide-excision repair
AMRN_RS04120	COG0779	Required for maturation of 30S ribosomal subunits
AMRN_RS04125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMRN_RS04150	COG0698	ribose 5-phosphate isomerase
AMRN_RS04155	COG0681	Belongs to the peptidase S26 family
AMRN_RS04160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMRN_RS04170	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AMRN_RS04175	COG0193	aminoacyl-tRNA hydrolase activity
AMRN_RS04190	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMRN_RS04200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMRN_RS04210	COG1758	RNA polymerase activity
AMRN_RS04215	COG0528	UMP kinase activity
AMRN_RS04225	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMRN_RS04230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMRN_RS04235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMRN_RS04245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMRN_RS04250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMRN_RS04265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMRN_RS04270	COG0305	Participates in initiation and elongation during chromosome replication
AMRN_RS04280	COG0166	Belongs to the GPI family
AMRN_RS04300	COG1943	Transposase
AMRN_RS04305	COG1793	dna ligase
AMRN_RS04315	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMRN_RS04315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMRN_RS04320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMRN_RS04330	COG0133	tryptophan synthase activity
AMRN_RS04340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMRN_RS04355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AMRN_RS04375	COG0673	inositol 2-dehydrogenase activity
AMRN_RS04380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMRN_RS04390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMRN_RS04430	COG1063	alcohol dehydrogenase
AMRN_RS04445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMRN_RS04450	COG0110	maltose O-acetyltransferase activity
AMRN_RS04455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMRN_RS04460	COG1086	Polysaccharide biosynthesis protein
AMRN_RS04485	COG3123	guanosine phosphorylase activity
AMRN_RS04505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMRN_RS04510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMRN_RS04520	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AMRN_RS04525	COG0585	pseudouridine synthase activity
AMRN_RS04540	COG0632	four-way junction helicase activity
AMRN_RS04545	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMRN_RS04555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMRN_RS04570	COG0573	inorganic phosphate transmembrane transporter activity
AMRN_RS04575	COG0581	inorganic phosphate transmembrane transporter activity
AMRN_RS04580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMRN_RS04590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMRN_RS04615	COG0051	transcription antitermination factor activity, RNA binding
AMRN_RS04620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMRN_RS04625	COG0088	Forms part of the polypeptide exit tunnel
AMRN_RS04630	COG0089	rRNA binding
AMRN_RS04635	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMRN_RS04640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMRN_RS04645	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMRN_RS04650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMRN_RS04655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMRN_RS04660	COG0255	Belongs to the universal ribosomal protein uL29 family
AMRN_RS04665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMRN_RS04670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AMRN_RS04675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMRN_RS04680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMRN_RS04685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMRN_RS04690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMRN_RS04695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMRN_RS04705	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMRN_RS04710	COG0200	Binds to the 23S rRNA
AMRN_RS04715	COG0201	protein transport
AMRN_RS04720	COG0024	Methionine aminopeptidase
AMRN_RS04725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMRN_RS04730	COG2199	diguanylate cyclase activity
AMRN_RS04740	COG1573	uracil-dna glycosylase
AMRN_RS04750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMRN_RS04765	COG1032	radical SAM domain protein
AMRN_RS04770	COG0563	adenylate kinase activity
AMRN_RS04785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMRN_RS04790	COG0322	excinuclease ABC activity
AMRN_RS04805	COG3201	nicotinamide mononucleotide transporter
AMRN_RS04825	COG0484	heat shock protein binding
AMRN_RS04830	COG1620	l-lactate permease
AMRN_RS04835	COG0840	transmembrane signaling receptor activity
AMRN_RS04855	COG0724	RNA recognition motif
AMRN_RS04860	COG0708	Exodeoxyribonuclease III
AMRN_RS04885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMRN_RS04890	COG0765	amino acid transport
AMRN_RS04905	COG1528	Iron-storage protein
AMRN_RS04910	COG1227	inorganic diphosphatase activity
AMRN_RS04920	COG0010	Belongs to the arginase family
AMRN_RS04965	COG0702	epimerase
AMRN_RS04970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMRN_RS04990	COG0326	Molecular chaperone. Has ATPase activity
AMRN_RS05015	COG0583	DNA-binding transcription factor activity
AMRN_RS05020	COG0326	Molecular chaperone. Has ATPase activity
AMRN_RS05030	COG1566	PFAM secretion protein HlyD family protein
AMRN_RS05080	COG0840	transmembrane signaling receptor activity
AMRN_RS05085	COG2207	Transcriptional regulator
AMRN_RS05085	COG4753	response regulator
AMRN_RS05090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMRN_RS05105	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AMRN_RS05115	COG1984	allophanate hydrolase subunit 2
AMRN_RS05125	COG3287	FIST C domain
AMRN_RS05125	COG2199	diguanylate cyclase activity
AMRN_RS05125	COG2200	EAL domain
AMRN_RS05140	COG2183	response to ionizing radiation
AMRN_RS05150	COG2890	protein-(glutamine-N5) methyltransferase activity
AMRN_RS05160	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AMRN_RS05175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMRN_RS05190	COG0492	ferredoxin-NADP+ reductase activity
AMRN_RS05195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMRN_RS05195	COG0475	glutathione-regulated potassium exporter activity
AMRN_RS05205	COG0693	protein deglycase activity
AMRN_RS05215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AMRN_RS05230	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AMRN_RS05235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AMRN_RS05245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMRN_RS05255	COG0439	Biotin carboxylase
AMRN_RS05260	COG0288	reversible hydration of carbon dioxide
AMRN_RS05305	COG2207	Transcriptional regulator
AMRN_RS05350	COG4999	Histidine kinase
AMRN_RS05350	COG3850	Histidine kinase
AMRN_RS05350	COG3437	response regulator, receiver
AMRN_RS05350	COG2205	protein histidine kinase activity
AMRN_RS05360	COG0745	RESPONSE REGULATOR receiver
AMRN_RS05390	COG0739	heme binding
AMRN_RS05395	COG0217	transcriptional regulatory protein
AMRN_RS05405	COG4783	chaperone-mediated protein folding
AMRN_RS05420	COG1960	acyl-CoA dehydrogenase activity
AMRN_RS05425	COG1049	propionate catabolic process, 2-methylcitrate cycle
AMRN_RS05435	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AMRN_RS05445	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AMRN_RS05450	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AMRN_RS05455	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AMRN_RS05460	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AMRN_RS05470	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AMRN_RS05475	COG0733	neurotransmitter:sodium symporter activity
AMRN_RS05480	COG2814	Major facilitator Superfamily
AMRN_RS05495	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AMRN_RS05500	COG0298	carbon dioxide binding
AMRN_RS05505	COG0409	Hydrogenase expression formation protein
AMRN_RS05510	COG0309	Hydrogenase expression formation protein (HypE)
AMRN_RS05515	COG1024	Enoyl-CoA hydratase
AMRN_RS05515	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMRN_RS05520	COG0375	protein maturation
AMRN_RS05525	COG3706	GGDEF domain
AMRN_RS05535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMRN_RS05535	COG1648	precorrin-2 dehydrogenase activity
AMRN_RS05555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AMRN_RS05560	COG2171	N-acyltransferase activity
AMRN_RS05570	COG1047	Peptidyl-prolyl cis-trans
AMRN_RS05590	COG2884	Cell division ATP-binding protein ftsE
AMRN_RS05595	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMRN_RS05605	COG0564	pseudouridine synthase activity
AMRN_RS05610	COG0772	Belongs to the SEDS family
AMRN_RS05620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMRN_RS05640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMRN_RS05645	COG0066	3-isopropylmalate dehydratase activity
AMRN_RS05650	COG0473	3-isopropylmalate dehydrogenase activity
AMRN_RS05665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMRN_RS05675	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMRN_RS05680	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AMRN_RS05685	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMRN_RS05690	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMRN_RS05695	COG0202	RNA polymerase activity
AMRN_RS05700	COG0203	ribosomal protein L17
AMRN_RS05705	COG0154	amidase activity
AMRN_RS05710	COG0516	GMP reductase activity
AMRN_RS05710	COG0517	IMP dehydrogenase activity
AMRN_RS05795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMRN_RS05805	COG2003	Belongs to the UPF0758 family
AMRN_RS05830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMRN_RS05835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMRN_RS05870	COG0420	3'-5' exonuclease activity
AMRN_RS05875	COG0419	ATPase involved in DNA repair
AMRN_RS05910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMRN_RS05910	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AMRN_RS05920	COG2084	Dehydrogenase
AMRN_RS05930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMRN_RS05935	COG0251	oxidation-reduction process
AMRN_RS05940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMRN_RS05945	COG1879	ABC-type sugar transport system periplasmic component
AMRN_RS05955	COG1846	Transcriptional regulator
AMRN_RS05975	COG1309	transcriptional regulator
AMRN_RS05985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMRN_RS05995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMRN_RS06000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMRN_RS06010	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMRN_RS06015	COG0471	metal ion transport
AMRN_RS06020	COG1193	negative regulation of DNA recombination
AMRN_RS06025	COG0668	transmembrane transport
AMRN_RS06040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMRN_RS06050	COG0454	-acetyltransferase
AMRN_RS06070	COG1742	UPF0060 membrane protein
AMRN_RS06080	COG1917	Cupin 2, conserved barrel domain protein
AMRN_RS06080	COG2207	Transcriptional regulator
AMRN_RS06085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMRN_RS06090	COG2258	MOSC domain
AMRN_RS06130	COG2824	Alkylphosphonate utilization operon protein PhnA
AMRN_RS06185	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMRN_RS06195	COG0778	Nitroreductase
AMRN_RS06205	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AMRN_RS06210	COG0840	transmembrane signaling receptor activity
AMRN_RS06215	COG0840	transmembrane signaling receptor activity
AMRN_RS06220	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMRN_RS06250	COG3046	protein related to deoxyribodipyrimidine photolyase
AMRN_RS06255	COG2200	EAL domain
AMRN_RS06260	COG0352	thiamine-phosphate diphosphorylase activity
AMRN_RS06265	COG0157	Belongs to the NadC ModD family
AMRN_RS06275	COG3842	ATPase activity
AMRN_RS06305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMRN_RS06315	COG0488	(ABC) transporter
AMRN_RS06330	COG1607	acyl-coa hydrolase
AMRN_RS06335	COG1607	acyl-coa hydrolase
AMRN_RS06340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMRN_RS06345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMRN_RS06350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AMRN_RS06355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMRN_RS06365	COG0114	fumarate hydratase activity
AMRN_RS06385	COG2030	dehydratase
AMRN_RS06405	COG2195	Cleaves the N-terminal amino acid of tripeptides
AMRN_RS06410	COG3287	FIST C domain
AMRN_RS06410	COG2200	EAL domain
AMRN_RS06410	COG2199	diguanylate cyclase activity
AMRN_RS06415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMRN_RS06415	COG1333	cytochrome c biogenesis protein
AMRN_RS06420	COG0500	methyltransferase
AMRN_RS06425	COG3706	GGDEF domain
AMRN_RS06425	COG2203	Gaf domain
AMRN_RS06425	COG5001	Diguanylate cyclase
AMRN_RS06425	COG4251	negative regulation of phosphorylation
AMRN_RS06440	COG2833	Protein of unknown function (DUF455)
AMRN_RS06445	COG0133	tryptophan synthase activity
AMRN_RS06450	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AMRN_RS06455	COG0484	heat shock protein binding
AMRN_RS06460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMRN_RS06465	COG1902	pentaerythritol trinitrate reductase activity
AMRN_RS06475	COG0778	Nitroreductase
AMRN_RS06480	COG1733	regulation of RNA biosynthetic process
AMRN_RS06485	COG0840	transmembrane signaling receptor activity
AMRN_RS06510	COG3153	acetyltransferase
AMRN_RS06510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMRN_RS06525	COG0745	RESPONSE REGULATOR receiver
AMRN_RS06560	COG0137	argininosuccinate synthase activity
AMRN_RS06570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMRN_RS06575	COG0802	atpase or kinase
AMRN_RS06580	COG1137	ATPase activity
AMRN_RS06585	COG3706	GGDEF domain
AMRN_RS06590	COG5002	protein histidine kinase activity
AMRN_RS06590	COG5001	Diguanylate cyclase
AMRN_RS06595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMRN_RS06605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMRN_RS06605	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMRN_RS06610	COG0745	RESPONSE REGULATOR receiver
AMRN_RS06625	COG0840	transmembrane signaling receptor activity
AMRN_RS06630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMRN_RS06640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMRN_RS06645	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMRN_RS06665	COG0745	RESPONSE REGULATOR receiver
AMRN_RS06670	COG0189	ligase activity
AMRN_RS06685	COG3852	Histidine kinase
AMRN_RS06690	COG0113	porphobilinogen synthase activity
AMRN_RS06695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMRN_RS06700	COG0357	Ribosomal RNA small subunit methyltransferase G
AMRN_RS06755	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AMRN_RS06760	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AMRN_RS06765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMRN_RS06770	COG3630	sodium ion export across plasma membrane
AMRN_RS06785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMRN_RS06785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMRN_RS06795	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AMRN_RS06820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMRN_RS06825	COG0612	Peptidase, M16
AMRN_RS06830	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMRN_RS06835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMRN_RS06840	COG0287	Prephenate dehydrogenase
AMRN_RS06845	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMRN_RS06860	COG0527	aspartate kinase activity
AMRN_RS06865	COG0494	nUDIX hydrolase
AMRN_RS06870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMRN_RS06875	COG2890	protein-(glutamine-N5) methyltransferase activity
AMRN_RS06880	COG0339	signal peptide processing
AMRN_RS06965	COG2815	serine threonine protein kinase
AMRN_RS06965	COG0515	serine threonine protein kinase
AMRN_RS07080	COG0582	viral genome integration into host DNA
AMRN_RS07085	COG2201	protein-glutamate methylesterase activity
AMRN_RS07090	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AMRN_RS07095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMRN_RS07110	COG1185	polyribonucleotide nucleotidyltransferase activity
AMRN_RS07120	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AMRN_RS07140	COG1160	GTP binding
AMRN_RS07150	COG1674	ftsk spoiiie
AMRN_RS07150	COG1196	nuclear chromosome segregation
AMRN_RS07155	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMRN_RS07160	COG0440	acetolactate synthase activity
AMRN_RS07165	COG0028	Belongs to the TPP enzyme family
AMRN_RS07170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMRN_RS07185	COG2203	Gaf domain
AMRN_RS07185	COG3706	GGDEF domain
AMRN_RS07185	COG4251	negative regulation of phosphorylation
AMRN_RS07185	COG5001	Diguanylate cyclase
AMRN_RS07200	COG3118	belongs to the thioredoxin family
AMRN_RS07210	COG1683	Conserved Protein
AMRN_RS07215	COG0037	tRNA processing
AMRN_RS07220	COG2056	Na+-H+ antiporter family
AMRN_RS07230	COG0189	ligase activity
AMRN_RS07230	COG4067	protein conserved in archaea
AMRN_RS07245	COG1012	belongs to the aldehyde dehydrogenase family
AMRN_RS07250	COG0410	ABC transporter
AMRN_RS07290	COG0745	RESPONSE REGULATOR receiver
AMRN_RS07310	COG0303	'Molybdopterin
AMRN_RS07325	COG1322	Protein conserved in bacteria
AMRN_RS07330	COG0501	Belongs to the peptidase M48B family
AMRN_RS07340	COG4191	Histidine kinase
AMRN_RS07345	COG0824	Thioesterase
AMRN_RS07350	COG2205	protein histidine kinase activity
AMRN_RS07360	COG0667	Aldo Keto reductase
AMRN_RS07375	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AMRN_RS07380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMRN_RS07390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMRN_RS07405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AMRN_RS07425	COG1797	cobyrinic acid a,c-diamide synthase activity
AMRN_RS07440	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AMRN_RS07480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMRN_RS07495	COG0546	phosphoglycolate phosphatase activity
AMRN_RS07505	COG0840	transmembrane signaling receptor activity
AMRN_RS07515	COG0848	biopolymer transport protein
AMRN_RS07520	COG0811	peptide transport
AMRN_RS07525	COG0642	Histidine kinase
AMRN_RS07530	COG0745	RESPONSE REGULATOR receiver
AMRN_RS07550	COG0788	formyltetrahydrofolate deformylase activity
AMRN_RS07555	COG0281	malic enzyme
AMRN_RS07555	COG0280	phosphate acetyltransferase
AMRN_RS07560	COG1496	oxidoreductase activity
AMRN_RS07565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMRN_RS07595	COG2186	Transcriptional regulator
AMRN_RS07600	COG2807	transmembrane transport
AMRN_RS07605	COG0301	tRNA thio-modification
AMRN_RS07605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMRN_RS07615	COG0754	glutathionylspermidine amidase activity
AMRN_RS07625	COG1663	tetraacyldisaccharide 4'-kinase activity
AMRN_RS07630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMRN_RS07635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMRN_RS07655	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMRN_RS07660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMRN_RS07665	COG0805	protein transport
AMRN_RS07670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMRN_RS07675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMRN_RS07680	COG0733	neurotransmitter:sodium symporter activity
AMRN_RS07715	COG4865	methylaspartate mutase activity
AMRN_RS07730	COG2863	cytochrome
AMRN_RS07735	COG2199	diguanylate cyclase activity
AMRN_RS07750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMRN_RS07765	COG0275	rRNA processing
AMRN_RS07775	COG0776	regulation of translation
AMRN_RS07800	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMRN_RS07815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMRN_RS07820	COG1917	Cupin 2, conserved barrel domain protein
AMRN_RS07835	COG0527	aspartate kinase activity
AMRN_RS07855	COG2863	cytochrome
AMRN_RS07865	COG0642	Histidine kinase
AMRN_RS07870	COG0745	RESPONSE REGULATOR receiver
AMRN_RS07960	COG2199	diguanylate cyclase activity
AMRN_RS07960	COG2200	EAL domain
AMRN_RS07960	COG3287	FIST C domain
AMRN_RS07970	COG1132	(ABC) transporter
AMRN_RS07975	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AMRN_RS07995	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AMRN_RS08000	COG0653	protein targeting
AMRN_RS08015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMRN_RS08030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMRN_RS08030	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AMRN_RS08040	COG2201	protein-glutamate methylesterase activity
AMRN_RS08055	COG0484	heat shock protein binding
AMRN_RS08060	COG0789	Transcriptional regulator
AMRN_RS08065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMRN_RS08070	COG0849	cell division
AMRN_RS08080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMRN_RS08090	COG1393	Belongs to the ArsC family
AMRN_RS08115	COG0768	penicillin binding
AMRN_RS08120	COG1338	Plays a role in the flagellum-specific transport system
AMRN_RS08145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMRN_RS08150	COG0456	acetyltransferase
AMRN_RS08155	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AMRN_RS08170	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AMRN_RS08175	COG0131	Imidazoleglycerol-phosphate dehydratase
AMRN_RS08180	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMRN_RS08190	COG0084	hydrolase, TatD family'
AMRN_RS08205	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AMRN_RS08210	COG0359	binds to the 23S rRNA
AMRN_RS08220	COG0163	prenyltransferase activity
AMRN_RS08225	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMRN_RS08230	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMRN_RS08235	COG0124	histidyl-tRNA synthetase
AMRN_RS08240	COG1166	arginine decarboxylase activity
AMRN_RS08245	COG1045	serine acetyltransferase
AMRN_RS08255	COG1473	amidohydrolase
AMRN_RS08260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMRN_RS08265	COG1012	belongs to the aldehyde dehydrogenase family
AMRN_RS08270	COG0006	proline dipeptidase activity
AMRN_RS08280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMRN_RS08290	COG1301	dicarboxylic acid transport
AMRN_RS08300	COG4536	flavin adenine dinucleotide binding
AMRN_RS08305	COG0748	coenzyme F420 binding
AMRN_RS08315	COG0259	pyridoxamine-phosphate oxidase activity
AMRN_RS08320	COG0386	Belongs to the glutathione peroxidase family
AMRN_RS08355	COG2011	ABC-type metal ion transport system permease component
AMRN_RS08360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMRN_RS08365	COG2223	nitrite transmembrane transporter activity
AMRN_RS08375	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AMRN_RS08380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMRN_RS08385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMRN_RS08410	COG3852	Histidine kinase
AMRN_RS08415	COG0745	RESPONSE REGULATOR receiver
AMRN_RS08420	COG0659	secondary active sulfate transmembrane transporter activity
AMRN_RS08425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMRN_RS08435	COG2264	protein methyltransferase activity
AMRN_RS08445	COG1489	DNA binding
AMRN_RS08460	COG2133	pyrroloquinoline quinone binding
AMRN_RS08465	COG1643	Atp-dependent helicase
AMRN_RS08470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMRN_RS08495	COG3287	FIST C domain
AMRN_RS08495	COG2200	EAL domain
AMRN_RS08495	COG2199	diguanylate cyclase activity
AMRN_RS08505	COG0596	Alpha beta hydrolase
AMRN_RS08530	COG1278	Cold shock
AMRN_RS08545	COG0513	Belongs to the DEAD box helicase family
AMRN_RS08550	COG1187	pseudouridine synthase activity
AMRN_RS08580	COG0840	transmembrane signaling receptor activity
AMRN_RS08620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMRN_RS08620	COG0519	Catalyzes the synthesis of GMP from XMP
AMRN_RS08635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMRN_RS08655	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AMRN_RS08665	COG0840	transmembrane signaling receptor activity
AMRN_RS08670	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AMRN_RS08680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMRN_RS08685	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMRN_RS08690	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AMRN_RS08700	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMRN_RS08705	COG0039	L-malate dehydrogenase activity
AMRN_RS08720	COG0488	(ABC) transporter
AMRN_RS08725	COG1610	YqeY-like protein
AMRN_RS08735	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMRN_RS08740	COG5001	Diguanylate cyclase
AMRN_RS08740	COG3300	MHYT domain
AMRN_RS08760	COG1136	(ABC) transporter
AMRN_RS08775	COG1320	monovalent cation:proton antiporter activity
AMRN_RS08780	COG2212	antiporter activity
AMRN_RS08785	COG1863	multisubunit Na H antiporter MnhE subunit
AMRN_RS08790	COG0651	ATP synthesis coupled electron transport
AMRN_RS08795	COG1006	Multisubunit Na H antiporter MnhC subunit
AMRN_RS08800	COG2111	Na H antiporter
AMRN_RS08800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AMRN_RS08805	COG0300	oxidoreductase activity
AMRN_RS08810	COG1757	Na H antiporter
AMRN_RS08815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMRN_RS08820	COG0742	ribosomal rna small subunit methyltransferase
AMRN_RS08825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AMRN_RS08830	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AMRN_RS08840	COG1418	mRNA catabolic process
AMRN_RS08850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMRN_RS08855	COG0552	protein localization to endoplasmic reticulum
AMRN_RS08870	COG5002	protein histidine kinase activity
AMRN_RS08875	COG3258	Cytochrome c
AMRN_RS08880	COG3150	esterase
AMRN_RS08895	COG0840	transmembrane signaling receptor activity
AMRN_RS08900	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AMRN_RS08915	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMRN_RS08930	COG0783	Belongs to the Dps family
AMRN_RS08935	COG1592	Rubrerythrin
AMRN_RS08970	COG0728	peptidoglycan biosynthetic process
AMRN_RS08975	COG1132	(ABC) transporter
AMRN_RS08980	COG0167	dihydroorotate dehydrogenase activity
AMRN_RS08990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMRN_RS08995	COG1028	Short-chain dehydrogenase reductase Sdr
AMRN_RS09000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMRN_RS09005	COG0750	zinc metalloprotease
AMRN_RS09010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AMRN_RS09030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AMRN_RS09035	COG1368	sulfuric ester hydrolase activity
AMRN_RS09040	COG3328	transposase activity
AMRN_RS09060	COG0189	ligase activity
AMRN_RS09075	COG0134	indole-3-glycerol-phosphate synthase activity
AMRN_RS09085	COG0727	PFAM Uncharacterised protein family (UPF0153)
AMRN_RS09090	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AMRN_RS09100	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMRN_RS09100	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMRN_RS09105	COG0028	Belongs to the TPP enzyme family
AMRN_RS09125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMRN_RS09130	COG2176	DNA-directed DNA polymerase activity
AMRN_RS09135	COG0135	phosphoribosylanthranilate isomerase activity
AMRN_RS09140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AMRN_RS09145	COG3008	intermembrane lipid transfer
AMRN_RS09150	COG2995	paraquat-inducible protein a
AMRN_RS09155	COG2995	paraquat-inducible protein a
AMRN_RS09160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMRN_RS09200	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AMRN_RS09210	COG3706	GGDEF domain
AMRN_RS09215	COG0666	response to abiotic stimulus
AMRN_RS09235	COG0642	Histidine kinase
AMRN_RS09240	COG0745	RESPONSE REGULATOR receiver
AMRN_RS09245	COG2855	membrane
AMRN_RS09250	COG0583	DNA-binding transcription factor activity
AMRN_RS09260	COG1666	GTP binding
AMRN_RS09280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMRN_RS09290	COG2363	Small membrane protein
AMRN_RS09300	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AMRN_RS09305	COG2252	PERMEase
AMRN_RS09315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMRN_RS09320	COG4977	sequence-specific DNA binding
AMRN_RS09325	COG3437	response regulator, receiver
AMRN_RS09325	COG0784	Response regulator, receiver
AMRN_RS09330	COG0640	Transcriptional regulator
AMRN_RS09335	COG2217	Heavy metal translocating P-type atpase
AMRN_RS09355	COG0745	RESPONSE REGULATOR receiver
AMRN_RS09365	COG0243	molybdopterin cofactor binding
AMRN_RS09370	COG1979	alcohol dehydrogenase
AMRN_RS09385	COG1918	ferrous iron import across plasma membrane
AMRN_RS09390	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AMRN_RS09390	COG1918	ferrous iron import across plasma membrane
AMRN_RS09430	COG0731	radical SAM domain protein
AMRN_RS09435	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AMRN_RS09445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMRN_RS09460	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AMRN_RS09470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMRN_RS09480	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMRN_RS09485	COG0859	PFAM glycosyl transferase family 9
AMRN_RS09515	COG0515	serine threonine protein kinase
AMRN_RS09520	COG0297	glycogen (starch) synthase activity
AMRN_RS09525	COG0463	Glycosyl transferase, family 2
AMRN_RS09570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AMRN_RS09590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMRN_RS09600	COG0493	'glutamate synthase
AMRN_RS09605	COG0069	glutamate synthase activity
AMRN_RS09605	COG0070	glutamate synthase
AMRN_RS09605	COG0067	glutamate synthase
AMRN_RS09645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMRN_RS09660	COG1942	4-Oxalocrotonate Tautomerase
AMRN_RS09695	COG1472	Belongs to the glycosyl hydrolase 3 family
AMRN_RS09715	COG2116	formate transmembrane transporter activity
AMRN_RS09730	COG3260	NADH ubiquinone oxidoreductase 20
AMRN_RS09740	COG3261	NADH dehydrogenase
AMRN_RS09740	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AMRN_RS09745	COG0651	ATP synthesis coupled electron transport
AMRN_RS09750	COG4237	Hydrogenase 4 membrane
AMRN_RS09755	COG0650	Formate hydrogenlyase subunit 4
AMRN_RS09760	COG0651	ATP synthesis coupled electron transport
AMRN_RS09765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMRN_RS09770	COG3383	formate dehydrogenase (NAD+) activity
AMRN_RS09775	COG3383	formate dehydrogenase (NAD+) activity
AMRN_RS09785	COG0596	Alpha beta hydrolase
AMRN_RS09790	COG4771	TonB-dependent receptor
AMRN_RS09810	COG1120	ATPase activity
AMRN_RS09815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMRN_RS09825	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AMRN_RS09830	COG3842	ATPase activity
AMRN_RS09835	COG0725	ABC transporter, periplasmic molybdate-binding protein
AMRN_RS09845	COG4662	Binding-protein-dependent transport system inner membrane component
AMRN_RS09850	COG2998	abc-type tungstate transport system, permease component
AMRN_RS09855	COG0303	'Molybdopterin
AMRN_RS09860	COG1104	cysteine desulfurase activity
AMRN_RS09865	COG2005	Transcriptional regulator
AMRN_RS09875	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMRN_RS09885	COG0437	4 iron, 4 sulfur cluster binding
AMRN_RS09910	COG0437	4 iron, 4 sulfur cluster binding
AMRN_RS09940	COG0437	4 iron, 4 sulfur cluster binding
AMRN_RS09945	COG0243	molybdopterin cofactor binding
AMRN_RS09945	COG3383	formate dehydrogenase (NAD+) activity
AMRN_RS09965	COG2204	response regulator
AMRN_RS09980	COG1305	Transglutaminase-like
AMRN_RS09985	COG0709	Synthesizes selenophosphate from selenide and ATP
AMRN_RS09990	COG1921	L-seryl-tRNASec selenium transferase activity
AMRN_RS10005	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMRN_RS10020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMRN_RS10025	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AMRN_RS10030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMRN_RS10045	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMRN_RS10055	COG0513	Belongs to the DEAD box helicase family
AMRN_RS10060	COG0840	transmembrane signaling receptor activity
AMRN_RS10065	COG0419	ATPase involved in DNA repair
AMRN_RS10105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMRN_RS10110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMRN_RS10115	COG1047	Peptidyl-prolyl cis-trans
AMRN_RS10130	COG0823	Involved in the tonB-independent uptake of proteins
AMRN_RS10140	COG0848	biopolymer transport protein
AMRN_RS10145	COG0811	peptide transport
AMRN_RS10150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMRN_RS10155	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMRN_RS10160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMRN_RS10165	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMRN_RS10170	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMRN_RS10175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMRN_RS10185	COG1475	DNA binding
AMRN_RS10190	COG1192	Involved in chromosome partitioning
AMRN_RS10195	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AMRN_RS10195	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AMRN_RS10210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMRN_RS10215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMRN_RS10220	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMRN_RS10225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMRN_RS10230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMRN_RS10235	COG0251	oxidation-reduction process
AMRN_RS10240	COG0358	DNA primase activity
AMRN_RS10250	COG0328	RNA-DNA hybrid ribonuclease activity
AMRN_RS10255	COG0571	ribonuclease III activity
AMRN_RS10260	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMRN_RS10270	COG1342	Belongs to the UPF0251 family
AMRN_RS10275	COG0501	Belongs to the peptidase M48B family
AMRN_RS10285	COG2062	phosphohistidine phosphatase, SixA
AMRN_RS10290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AMRN_RS10300	COG0706	membrane insertase activity
AMRN_RS10305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AMRN_RS10315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AMRN_RS10325	COG0542	response to heat
AMRN_RS10340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMRN_RS10350	COG5001	Diguanylate cyclase
AMRN_RS10350	COG5002	protein histidine kinase activity
AMRN_RS10360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMRN_RS10360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMRN_RS10365	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMRN_RS10375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMRN_RS10390	COG2610	gluconate transmembrane transporter activity
AMRN_RS10400	COG3118	belongs to the thioredoxin family
AMRN_RS10405	COG0450	alkyl hydroperoxide reductase
AMRN_RS10410	COG0028	Belongs to the TPP enzyme family
AMRN_RS10445	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMRN_RS10455	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AMRN_RS10480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMRN_RS10490	COG0739	heme binding
AMRN_RS10490	COG1196	nuclear chromosome segregation
AMRN_RS10490	COG0741	lytic transglycosylase activity
AMRN_RS10495	COG2239	Acts as a magnesium transporter
AMRN_RS10505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMRN_RS10520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMRN_RS10535	COG0415	Belongs to the DNA photolyase family
AMRN_RS10555	COG0351	phosphomethylpyrimidine kinase
AMRN_RS10560	COG3279	Response regulator of the LytR AlgR family
AMRN_RS10565	COG3275	phosphorelay sensor kinase activity
AMRN_RS10575	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMRN_RS10585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AMRN_RS10590	COG0606	chelatase, subunit chli
AMRN_RS10620	COG0210	DNA helicase
AMRN_RS10675	COG0840	transmembrane signaling receptor activity
AMRN_RS10685	COG0242	peptide deformylase activity
AMRN_RS10690	COG0740	serine-type endopeptidase activity
AMRN_RS10695	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMRN_RS10715	COG2326	polyphosphate kinase activity
AMRN_RS10730	COG1773	rubredoxin
AMRN_RS10765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMRN_RS10775	COG0840	transmembrane signaling receptor activity
AMRN_RS10785	COG0668	transmembrane transport
AMRN_RS10790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMRN_RS10810	COG1122	ATPase activity
AMRN_RS10815	COG0348	domain, Protein
AMRN_RS10830	COG0437	4 iron, 4 sulfur cluster binding
AMRN_RS10845	COG4263	nitrous-oxide reductase activity
AMRN_RS10860	COG1271	oxidase subunit
AMRN_RS10870	COG1342	Belongs to the UPF0251 family
AMRN_RS10895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMRN_RS10910	COG4771	TonB-dependent receptor
AMRN_RS10935	COG0716	FMN binding
AMRN_RS10960	COG0745	RESPONSE REGULATOR receiver
AMRN_RS10965	COG0716	FMN binding
AMRN_RS10970	COG0716	FMN binding
AMRN_RS11015	COG3706	GGDEF domain
AMRN_RS11025	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AMRN_RS11050	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AMRN_RS11055	COG0159	tryptophan synthase activity
AMRN_RS11060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMRN_RS11065	COG2255	four-way junction helicase activity
AMRN_RS11070	COG0628	permease
AMRN_RS11085	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AMRN_RS11090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMRN_RS11090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMRN_RS11100	COG0542	response to heat
AMRN_RS11105	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMRN_RS11110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AMRN_RS11125	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AMRN_RS11140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMRN_RS11150	COG1157	protein secretion by the type III secretion system
AMRN_RS11160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMRN_RS11175	COG1558	bacterial-type flagellum-dependent cell motility
AMRN_RS11180	COG1677	Flagellar hook-basal body complex protein FliE
AMRN_RS11190	COG0455	bacterial-type flagellum organization
AMRN_RS11195	COG1419	protein localization to endoplasmic reticulum
AMRN_RS11210	COG3951	Flagellar rod assembly protein muramidase FlgJ
AMRN_RS11220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMRN_RS11245	COG1749	Flagellar hook protein flgE
AMRN_RS11250	COG1749	Flagellar hook protein flgE
AMRN_RS11260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMRN_RS11270	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMRN_RS11275	COG1766	The M ring may be actively involved in energy transduction
AMRN_RS11280	COG1815	bacterial-type flagellum-dependent cell motility
AMRN_RS11285	COG4786	Flagellar basal body rod
AMRN_RS11295	COG0745	RESPONSE REGULATOR receiver
AMRN_RS11315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMRN_RS11325	COG0228	four-way junction DNA binding
AMRN_RS11330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMRN_RS11340	COG1519	Transferase
AMRN_RS11350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AMRN_RS11355	COG0752	glycyl-tRNA synthetase alpha subunit
AMRN_RS11360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AMRN_RS11370	COG0826	peptidase U32
AMRN_RS11375	COG0840	transmembrane signaling receptor activity
AMRN_RS11375	COG0840	transmembrane signaling receptor activity
AMRN_RS11385	COG0497	DNA recombination
AMRN_RS11390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMRN_RS11395	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMRN_RS11400	COG0049	tRNA binding
AMRN_RS11405	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMRN_RS11410	COG2814	Major facilitator Superfamily
AMRN_RS11430	COG1132	(ABC) transporter
AMRN_RS11435	COG1132	(ABC) transporter
AMRN_RS11435	COG2375	cellular response to nickel ion
AMRN_RS11445	COG4771	TonB-dependent receptor
AMRN_RS11455	COG1671	Belongs to the UPF0178 family
AMRN_RS11460	COG4895	conserved protein (DUF2196)
AMRN_RS11515	COG0745	RESPONSE REGULATOR receiver
AMRN_RS11530	COG2860	membrane
AMRN_RS11550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMRN_RS11555	COG0085	RNA polymerase activity
AMRN_RS11560	COG0222	ribosome binding
AMRN_RS11565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMRN_RS11570	COG0081	regulation of translation
AMRN_RS11575	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMRN_RS11580	COG0250	Participates in transcription elongation, termination and antitermination
AMRN_RS11595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMRN_RS11600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMRN_RS11625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMRN_RS11630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMRN_RS11635	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AMRN_RS11640	COG2204	response regulator
AMRN_RS11645	COG0444	Belongs to the ABC transporter superfamily
AMRN_RS11650	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMRN_RS11655	COG0174	glutamine synthetase
AMRN_RS11660	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AMRN_RS11670	COG0314	molybdopterin synthase activity
AMRN_RS11680	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AMRN_RS11685	COG1968	undecaprenyl-diphosphatase activity
AMRN_RS11695	COG0772	Belongs to the SEDS family
AMRN_RS11700	COG0768	penicillin binding
AMRN_RS11705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMRN_RS11750	COG0512	Glutamine amidotransferase of anthranilate synthase
AMRN_RS11760	COG1840	ABC-type Fe3 transport system, periplasmic component
AMRN_RS11770	COG3842	ATPase activity
AMRN_RS11775	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AMRN_RS11780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMRN_RS11785	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMRN_RS11790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMRN_RS11795	COG0649	NAD binding
AMRN_RS11795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMRN_RS11810	COG0372	Belongs to the citrate synthase family
AMRN_RS11815	COG1034	ATP synthesis coupled electron transport
AMRN_RS11820	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMRN_RS11825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMRN_RS11830	COG0839	Belongs to the complex I subunit 6 family
AMRN_RS11835	COG0713	ATP synthesis coupled electron transport
AMRN_RS11840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AMRN_RS11850	COG1007	ATP synthesis coupled electron transport
AMRN_RS11860	COG1053	succinate dehydrogenase
AMRN_RS11865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMRN_RS11875	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AMRN_RS11895	COG3301	Polysulphide reductase, NrfD
AMRN_RS11900	COG2207	Transcriptional regulator
AMRN_RS11905	COG1929	Belongs to the glycerate kinase type-1 family
AMRN_RS11920	COG0038	chloride channel
AMRN_RS11935	COG1012	belongs to the aldehyde dehydrogenase family
AMRN_RS11970	COG2095	MarC family integral membrane protein
AMRN_RS11975	COG0765	amino acid transport
AMRN_RS11995	COG0500	methyltransferase
AMRN_RS12005	COG1335	isochorismatase
AMRN_RS12025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AMRN_RS12030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AMRN_RS12035	COG0514	ATP-dependent DNA helicase (RecQ)
AMRN_RS12055	COG1280	lysine exporter protein (LysE YggA)
AMRN_RS12065	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AMRN_RS12075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMRN_RS12080	COG2828	Protein conserved in bacteria
AMRN_RS12090	COG0181	hydroxymethylbilane synthase activity
AMRN_RS12105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AMRN_RS12120	COG0784	Response regulator, receiver
AMRN_RS12125	COG1629	transport
AMRN_RS12125	COG4774	siderophore transport
AMRN_RS12130	COG2382	esterase
AMRN_RS12135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMRN_RS12140	COG0450	alkyl hydroperoxide reductase
AMRN_RS12150	COG0105	UTP biosynthetic process
AMRN_RS12160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMRN_RS12165	COG0416	fatty acid biosynthetic process
AMRN_RS12170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMRN_RS12180	COG1687	branched-chain amino acid
AMRN_RS12185	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AMRN_RS12215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMRN_RS12225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMRN_RS12240	COG1704	LemA family
AMRN_RS12265	COG1280	lysine exporter protein (LysE YggA)
AMRN_RS12285	COG0469	pyruvate kinase activity
AMRN_RS12305	COG0642	Histidine kinase
AMRN_RS12310	COG0745	RESPONSE REGULATOR receiver
AMRN_RS12320	COG0792	nuclease activity
AMRN_RS12325	COG0840	transmembrane signaling receptor activity
AMRN_RS12330	COG0156	8-amino-7-oxononanoate synthase activity
AMRN_RS12340	COG0288	reversible hydration of carbon dioxide
AMRN_RS12350	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMRN_RS12360	COG2121	Domain of unknown function (DUF374)
AMRN_RS12365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMRN_RS12375	COG0195	Participates in both transcription termination and antitermination
AMRN_RS12380	COG0215	cysteine-tRNA ligase activity
AMRN_RS12385	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMRN_RS12390	COG0629	single-stranded DNA binding
AMRN_RS12395	COG0360	Binds together with S18 to 16S ribosomal RNA
AMRN_RS12400	COG1466	dna polymerase III delta subunit
AMRN_RS12405	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AMRN_RS12410	COG0557	exoribonuclease II activity
AMRN_RS12420	COG3852	Histidine kinase
AMRN_RS12425	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AMRN_RS12445	COG2205	protein histidine kinase activity
AMRN_RS12450	COG0745	RESPONSE REGULATOR receiver
AMRN_RS12455	COG3301	Polysulphide reductase, NrfD
AMRN_RS12460	COG0437	4 iron, 4 sulfur cluster binding
AMRN_RS12465	COG0243	molybdopterin cofactor binding
AMRN_RS12480	COG0436	Aminotransferase
AMRN_RS12490	COG0343	queuine tRNA-ribosyltransferase activity
AMRN_RS12495	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMRN_RS12500	COG1393	Belongs to the ArsC family
AMRN_RS12505	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMRN_RS12515	COG0560	Phosphoserine phosphatase
AMRN_RS12520	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AMRN_RS12520	COG0646	methionine synthase
AMRN_RS12525	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMRN_RS12530	COG0784	Response regulator, receiver
AMRN_RS12530	COG3437	response regulator, receiver
AMRN_RS12535	COG0736	holo-[acyl-carrier-protein] synthase activity
AMRN_RS12540	COG0601	transmembrane transport
AMRN_RS12545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMRN_RS12550	COG0745	RESPONSE REGULATOR receiver
AMRN_RS12560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMRN_RS12580	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AMRN_RS12615	COG1987	bacterial-type flagellum assembly
AMRN_RS12625	COG1706	bacterial-type flagellum-dependent cell motility
AMRN_RS12630	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMRN_RS12640	COG3069	C4-dicarboxylate transmembrane transporter activity
AMRN_RS12650	COG3069	C4-dicarboxylate transmembrane transporter activity
AMRN_RS12655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMRN_RS12660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMRN_RS12665	COG0540	Belongs to the ATCase OTCase family
AMRN_RS12675	COG0004	ammonium transporteR
AMRN_RS12680	COG0347	Belongs to the P(II) protein family
AMRN_RS12685	COG0004	ammonium transporteR
AMRN_RS12700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMRN_RS12705	COG0204	Acyl-transferase
AMRN_RS12705	COG0318	PFAM AMP-dependent synthetase and ligase
AMRN_RS12710	COG0640	Transcriptional regulator
AMRN_RS12715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AMRN_RS12720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMRN_RS12735	COG0598	Magnesium transport protein CorA
AMRN_RS12740	COG0659	secondary active sulfate transmembrane transporter activity
AMRN_RS12750	COG2962	Rard protein
AMRN_RS12760	COG1253	flavin adenine dinucleotide binding
AMRN_RS12765	COG1346	cytolysis
AMRN_RS12780	COG0840	transmembrane signaling receptor activity
AMRN_RS12785	COG0745	RESPONSE REGULATOR receiver
AMRN_RS12790	COG5000	phosphorelay sensor kinase activity
AMRN_RS12795	COG0252	asparaginase activity
AMRN_RS12800	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AMRN_RS12805	COG1027	Aspartate ammonia-lyase
AMRN_RS12810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMRN_RS12815	COG1053	succinate dehydrogenase
AMRN_RS12825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AMRN_RS12850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMRN_RS12870	COG0628	permease
AMRN_RS12875	COG3852	Histidine kinase
AMRN_RS12895	COG0745	RESPONSE REGULATOR receiver
AMRN_RS12930	COG0129	dihydroxy-acid dehydratase activity
AMRN_RS12940	COG0745	RESPONSE REGULATOR receiver
AMRN_RS12945	COG0642	Histidine kinase
AMRN_RS12950	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AMRN_RS12960	COG0745	RESPONSE REGULATOR receiver
AMRN_RS12975	COG1492	cobalamin metabolic process
AMRN_RS12980	COG1490	D-aminoacyl-tRNA deacylase activity
AMRN_RS12995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMRN_RS13000	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AMRN_RS13010	COG2095	MarC family integral membrane protein
AMRN_RS13015	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AMRN_RS13025	COG4191	Histidine kinase
AMRN_RS13045	COG3118	belongs to the thioredoxin family
AMRN_RS13065	COG0688	phosphatidylethanolamine metabolic process
AMRN_RS13075	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AMRN_RS13080	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AMRN_RS13090	COG0443	Heat shock 70 kDa protein
AMRN_RS13095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMRN_RS13100	COG1420	regulation of RNA biosynthetic process
AMRN_RS13120	COG2358	TRAP transporter, solute receptor (TAXI family
AMRN_RS13135	COG0745	RESPONSE REGULATOR receiver
AMRN_RS13145	COG0101	tRNA pseudouridine synthase activity
AMRN_RS13155	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AMRN_RS13160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMRN_RS13165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMRN_RS13170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMRN_RS13185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMRN_RS13240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMRN_RS13250	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AMRN_RS13260	COG2089	acid synthase
AMRN_RS13265	COG2226	methyltransferase
AMRN_RS13280	COG3980	spore coat polysaccharide biosynthesis protein
AMRN_RS13285	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMRN_RS13290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMRN_RS13300	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMRN_RS13310	COG2089	acid synthase
AMRN_RS13320	COG1086	Polysaccharide biosynthesis protein
AMRN_RS13325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMRN_RS13330	COG0148	phosphopyruvate hydratase activity
AMRN_RS13345	COG0569	domain protein
AMRN_RS13345	COG0475	glutathione-regulated potassium exporter activity
AMRN_RS13350	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMRN_RS13370	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AMRN_RS13380	COG1007	ATP synthesis coupled electron transport
AMRN_RS13390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AMRN_RS13395	COG0713	ATP synthesis coupled electron transport
AMRN_RS13400	COG0839	Belongs to the complex I subunit 6 family
AMRN_RS13405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMRN_RS13410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMRN_RS13430	COG0649	NAD binding
AMRN_RS13440	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMRN_RS13445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMRN_RS13450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMRN_RS13470	COG0488	(ABC) transporter
AMRN_RS13480	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AMRN_RS13490	COG3287	FIST C domain
AMRN_RS13490	COG2200	EAL domain
AMRN_RS13490	COG2199	diguanylate cyclase activity
AMRN_RS13510	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AMRN_RS13520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMRN_RS13525	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMRN_RS13530	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMRN_RS13535	COG1077	Cell shape determining protein MreB Mrl
AMRN_RS13565	COG0445	tRNA wobble uridine modification
AMRN_RS13575	COG1960	acyl-CoA dehydrogenase activity
AMRN_RS13590	COG2030	dehydratase
AMRN_RS13600	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMRN_RS13620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMRN_RS13625	COG2030	dehydratase
AMRN_RS13640	COG0644	oxidoreductase
AMRN_RS13645	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AMRN_RS13655	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AMRN_RS13665	COG0348	domain, Protein
AMRN_RS13670	COG0504	CTP synthase activity
AMRN_RS13675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AMRN_RS13705	COG0587	DNA-directed DNA polymerase activity
AMRN_RS13710	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMRN_RS13735	COG0315	cyclic pyranopterin monophosphate synthase activity
AMRN_RS13740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AMRN_RS13745	COG0471	metal ion transport
AMRN_RS13750	COG0628	permease
AMRN_RS13785	COG0670	Belongs to the BI1 family
AMRN_RS13790	COG0352	thiamine-phosphate diphosphorylase activity
AMRN_RS13800	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMRN_RS13810	COG0233	cytoplasmic translational termination
AMRN_RS13815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMRN_RS13825	COG2814	Major facilitator Superfamily
AMRN_RS13830	COG3022	response to hydroperoxide
AMRN_RS13835	COG3012	SEC-C Motif Domain Protein
AMRN_RS13850	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMRN_RS13855	COG1704	LemA family
AMRN_RS13895	COG0415	Belongs to the DNA photolyase family
AMRN_RS13900	COG0415	Belongs to the DNA photolyase family
AMRN_RS13905	COG2081	HI0933 family
AMRN_RS13920	COG1959	2 iron, 2 sulfur cluster binding
AMRN_RS13935	COG0175	sulfate reduction
AMRN_RS13940	COG0175	sulfate reduction
AMRN_RS13945	COG2895	sulfate adenylyltransferase (ATP) activity
AMRN_RS13950	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMRN_RS13955	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMRN_RS13960	COG0840	transmembrane signaling receptor activity
AMRN_RS13965	COG1408	metallophosphoesterase
AMRN_RS13980	COG1217	gtp-binding protein TYPA
AMRN_RS13990	COG0577	efflux transmembrane transporter activity
AMRN_RS13990	COG1136	(ABC) transporter
AMRN_RS14015	COG1408	metallophosphoesterase
AMRN_RS14020	COG0745	RESPONSE REGULATOR receiver
AMRN_RS14030	COG0784	Response regulator, receiver
AMRN_RS14030	COG3437	response regulator, receiver
AMRN_RS14035	COG2391	methyltransferase activity
AMRN_RS14040	COG0425	Belongs to the sulfur carrier protein TusA family
AMRN_RS14045	COG2066	Belongs to the glutaminase family
AMRN_RS14075	COG0745	RESPONSE REGULATOR receiver
AMRN_RS14080	COG0642	Histidine kinase
AMRN_RS14085	COG2860	membrane
AMRN_RS14090	COG0745	RESPONSE REGULATOR receiver
AMRN_RS14100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group