locus-tag	class	description
ASUIS_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASUIS_RS00010	COG0592	DNA-directed DNA polymerase activity
ASUIS_RS00015	COG0187	DNA topoisomerase II activity
ASUIS_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASUIS_RS00035	COG1238	metal cluster binding
ASUIS_RS00045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASUIS_RS00070	COG1053	succinate dehydrogenase
ASUIS_RS00075	COG0667	Aldo Keto reductase
ASUIS_RS00090	COG0500	methyltransferase
ASUIS_RS00095	COG3842	ATPase activity
ASUIS_RS00120	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ASUIS_RS00125	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ASUIS_RS00135	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ASUIS_RS00150	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ASUIS_RS00155	COG0633	Ferredoxin
ASUIS_RS00175	COG0716	FMN binding
ASUIS_RS00210	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ASUIS_RS00220	COG0840	transmembrane signaling receptor activity
ASUIS_RS00225	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ASUIS_RS00245	COG0426	domain, Protein
ASUIS_RS00270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASUIS_RS00300	COG0564	pseudouridine synthase activity
ASUIS_RS00305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASUIS_RS00310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASUIS_RS00315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASUIS_RS00335	COG1151	hydroxylamine reductase activity
ASUIS_RS00345	COG0493	'glutamate synthase
ASUIS_RS00360	COG0604	alcohol dehydrogenase
ASUIS_RS00365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASUIS_RS00370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASUIS_RS00385	COG1620	l-lactate permease
ASUIS_RS00390	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS00395	COG4191	Histidine kinase
ASUIS_RS00400	COG1556	Lactate utilization protein
ASUIS_RS00405	COG1139	Iron-sulfur cluster binding protein
ASUIS_RS00410	COG0247	lactate metabolic process
ASUIS_RS00420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASUIS_RS00420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASUIS_RS00425	COG0511	ligase activity, forming carbon-carbon bonds
ASUIS_RS00430	COG0439	Biotin carboxylase
ASUIS_RS00435	COG0513	Belongs to the DEAD box helicase family
ASUIS_RS00440	COG0306	phosphate transporter
ASUIS_RS00450	COG0367	asparagine synthase
ASUIS_RS00460	COG0778	Nitroreductase
ASUIS_RS00465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASUIS_RS00470	COG1053	succinate dehydrogenase
ASUIS_RS00480	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASUIS_RS00485	COG1981	membrane
ASUIS_RS00490	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ASUIS_RS00490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASUIS_RS00495	COG1187	pseudouridine synthase activity
ASUIS_RS00500	COG0517	IMP dehydrogenase activity
ASUIS_RS00500	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ASUIS_RS00505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ASUIS_RS00510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASUIS_RS00515	COG0107	imidazoleglycerol-phosphate synthase activity
ASUIS_RS00530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASUIS_RS00535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASUIS_RS00540	COG0724	RNA recognition motif
ASUIS_RS00545	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS00550	COG0642	Histidine kinase
ASUIS_RS00570	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASUIS_RS00575	COG2353	YceI-like domain
ASUIS_RS00585	COG0534	Mate efflux family protein
ASUIS_RS00590	COG0460	homoserine dehydrogenase
ASUIS_RS00595	COG0436	Aminotransferase
ASUIS_RS00610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ASUIS_RS00615	COG0254	rRNA binding
ASUIS_RS00620	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASUIS_RS00645	COG3706	GGDEF domain
ASUIS_RS00650	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ASUIS_RS00655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASUIS_RS00660	COG0237	dephospho-CoA kinase activity
ASUIS_RS00665	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ASUIS_RS00670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASUIS_RS00675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASUIS_RS00680	COG1741	Belongs to the pirin family
ASUIS_RS00695	COG1846	Transcriptional regulator
ASUIS_RS00700	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASUIS_RS00705	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ASUIS_RS00710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASUIS_RS00720	COG0505	Belongs to the CarA family
ASUIS_RS00725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASUIS_RS00735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASUIS_RS00735	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASUIS_RS00750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASUIS_RS00755	COG0489	protein tyrosine kinase activity
ASUIS_RS00760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASUIS_RS00760	COG0140	phosphoribosyl-ATP diphosphatase activity
ASUIS_RS00790	COG0646	methionine synthase
ASUIS_RS00790	COG1410	methionine synthase
ASUIS_RS00805	COG3647	Membrane
ASUIS_RS00810	COG1979	alcohol dehydrogenase
ASUIS_RS00835	COG1854	S-ribosylhomocysteine lyase activity
ASUIS_RS00860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASUIS_RS00865	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASUIS_RS00880	COG3180	Ammonia monooxygenase
ASUIS_RS00890	COG1013	pyruvate-flavodoxin oxidoreductase activity
ASUIS_RS00895	COG0674	pyruvate-flavodoxin oxidoreductase activity
ASUIS_RS00905	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ASUIS_RS00910	COG0546	phosphoglycolate phosphatase activity
ASUIS_RS00920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASUIS_RS00925	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASUIS_RS00930	COG2205	protein histidine kinase activity
ASUIS_RS00935	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS00945	COG0704	Plays a role in the regulation of phosphate uptake
ASUIS_RS00950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASUIS_RS00955	COG0581	inorganic phosphate transmembrane transporter activity
ASUIS_RS00960	COG0573	inorganic phosphate transmembrane transporter activity
ASUIS_RS00970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASUIS_RS00980	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASUIS_RS00985	COG0268	Binds directly to 16S ribosomal RNA
ASUIS_RS00990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASUIS_RS00995	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASUIS_RS01000	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASUIS_RS01005	COG0746	molybdenum cofactor guanylyltransferase activity
ASUIS_RS01010	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASUIS_RS01025	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASUIS_RS01030	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASUIS_RS01035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASUIS_RS01040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASUIS_RS01070	COG0575	Belongs to the CDS family
ASUIS_RS01075	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASUIS_RS01090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASUIS_RS01100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ASUIS_RS01100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASUIS_RS01105	COG2022	thiamine diphosphate biosynthetic process
ASUIS_RS01140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASUIS_RS01155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ASUIS_RS01175	COG2199	diguanylate cyclase activity
ASUIS_RS01185	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS01195	COG2274	protein secretion by the type I secretion system
ASUIS_RS01200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASUIS_RS01215	COG4191	Histidine kinase
ASUIS_RS01220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASUIS_RS01245	COG1346	cytolysis
ASUIS_RS01250	COG0640	Transcriptional regulator
ASUIS_RS01260	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASUIS_RS01275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASUIS_RS01285	COG1742	UPF0060 membrane protein
ASUIS_RS01305	COG1301	dicarboxylic acid transport
ASUIS_RS01320	COG4191	Histidine kinase
ASUIS_RS01330	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ASUIS_RS01355	COG0004	ammonium transporteR
ASUIS_RS01360	COG0004	ammonium transporteR
ASUIS_RS01370	COG0418	dihydroorotase activity
ASUIS_RS01375	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASUIS_RS01380	COG1706	bacterial-type flagellum-dependent cell motility
ASUIS_RS01415	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ASUIS_RS01420	COG4786	Flagellar basal body rod
ASUIS_RS01420	COG1256	bacterial-type flagellum assembly
ASUIS_RS01425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASUIS_RS01445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASUIS_RS01450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASUIS_RS01455	COG0601	transmembrane transport
ASUIS_RS01460	COG0736	holo-[acyl-carrier-protein] synthase activity
ASUIS_RS01465	COG0786	glutamate:sodium symporter activity
ASUIS_RS01470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASUIS_RS01480	COG0560	Phosphoserine phosphatase
ASUIS_RS01490	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ASUIS_RS01500	COG1393	Belongs to the ArsC family
ASUIS_RS01505	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASUIS_RS01510	COG0343	queuine tRNA-ribosyltransferase activity
ASUIS_RS01520	COG0436	Aminotransferase
ASUIS_RS01535	COG0758	DNA mediated transformation
ASUIS_RS01540	COG2861	carbohydrate metabolic process
ASUIS_RS01545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASUIS_RS01550	COG0557	exoribonuclease II activity
ASUIS_RS01560	COG0360	Binds together with S18 to 16S ribosomal RNA
ASUIS_RS01565	COG0629	single-stranded DNA binding
ASUIS_RS01570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASUIS_RS01580	COG0215	cysteine-tRNA ligase activity
ASUIS_RS01585	COG0195	Participates in both transcription termination and antitermination
ASUIS_RS01595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASUIS_RS01600	COG2121	Domain of unknown function (DUF374)
ASUIS_RS01610	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ASUIS_RS01620	COG0288	reversible hydration of carbon dioxide
ASUIS_RS01625	COG0156	8-amino-7-oxononanoate synthase activity
ASUIS_RS01630	COG0792	nuclease activity
ASUIS_RS01650	COG0469	pyruvate kinase activity
ASUIS_RS01660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASUIS_RS01670	COG0540	Belongs to the ATCase OTCase family
ASUIS_RS01680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASUIS_RS01695	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ASUIS_RS01705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASUIS_RS01710	COG0416	fatty acid biosynthetic process
ASUIS_RS01715	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASUIS_RS01725	COG0105	UTP biosynthetic process
ASUIS_RS01735	COG0450	alkyl hydroperoxide reductase
ASUIS_RS01740	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASUIS_RS01745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASUIS_RS01750	COG2011	ABC-type metal ion transport system permease component
ASUIS_RS01765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASUIS_RS01770	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASUIS_RS01775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASUIS_RS01785	COG0181	hydroxymethylbilane synthase activity
ASUIS_RS01800	COG2828	Protein conserved in bacteria
ASUIS_RS01805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ASUIS_RS01810	COG0372	Belongs to the citrate synthase family
ASUIS_RS01815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ASUIS_RS01825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASUIS_RS01870	COG1335	isochorismatase
ASUIS_RS01875	COG2823	Periplasmic or secreted lipoprotein
ASUIS_RS01895	COG0514	ATP-dependent DNA helicase (RecQ)
ASUIS_RS01905	COG3437	response regulator, receiver
ASUIS_RS01905	COG0784	Response regulator, receiver
ASUIS_RS01915	COG1451	nucleotide metabolic process
ASUIS_RS01935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASUIS_RS01940	COG1053	succinate dehydrogenase
ASUIS_RS01950	COG1007	ATP synthesis coupled electron transport
ASUIS_RS01960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASUIS_RS01965	COG0713	ATP synthesis coupled electron transport
ASUIS_RS01970	COG0839	Belongs to the complex I subunit 6 family
ASUIS_RS01975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASUIS_RS01980	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ASUIS_RS01990	COG0372	Belongs to the citrate synthase family
ASUIS_RS02005	COG0649	NAD binding
ASUIS_RS02005	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASUIS_RS02010	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASUIS_RS02015	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASUIS_RS02020	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ASUIS_RS02025	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASUIS_RS02030	COG3610	response to peptide
ASUIS_RS02035	COG2966	Psort location CytoplasmicMembrane, score
ASUIS_RS02045	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ASUIS_RS02050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASUIS_RS02070	COG1971	Probably functions as a manganese efflux pump
ASUIS_RS02090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASUIS_RS02095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASUIS_RS02095	COG1333	cytochrome c biogenesis protein
ASUIS_RS02100	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ASUIS_RS02105	COG3005	denitrification pathway
ASUIS_RS02120	COG0840	transmembrane signaling receptor activity
ASUIS_RS02140	COG3043	anaerobic respiration
ASUIS_RS02145	COG0348	domain, Protein
ASUIS_RS02150	COG0437	4 iron, 4 sulfur cluster binding
ASUIS_RS02155	COG0243	molybdopterin cofactor binding
ASUIS_RS02170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASUIS_RS02180	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS02185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASUIS_RS02190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASUIS_RS02190	COG1648	precorrin-2 dehydrogenase activity
ASUIS_RS02205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASUIS_RS02210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASUIS_RS02215	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASUIS_RS02225	COG2404	hydrolase activity, acting on ester bonds
ASUIS_RS02230	COG1832	CoA-binding protein
ASUIS_RS02235	COG0642	Histidine kinase
ASUIS_RS02240	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS02245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASUIS_RS02250	COG0191	fructose-bisphosphate aldolase activity
ASUIS_RS02265	COG2205	protein histidine kinase activity
ASUIS_RS02265	COG0784	Response regulator, receiver
ASUIS_RS02280	COG1278	Cold shock
ASUIS_RS02285	COG0848	biopolymer transport protein
ASUIS_RS02290	COG0811	peptide transport
ASUIS_RS02300	COG4191	Histidine kinase
ASUIS_RS02305	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASUIS_RS02310	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASUIS_RS02320	COG0142	geranyltranstransferase activity
ASUIS_RS02325	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASUIS_RS02330	COG0442	prolyl-tRNA aminoacylation
ASUIS_RS02335	COG0668	transmembrane transport
ASUIS_RS02340	COG0617	tRNA 3'-terminal CCA addition
ASUIS_RS02355	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASUIS_RS02360	COG1862	Preprotein translocase
ASUIS_RS02365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASUIS_RS02370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASUIS_RS02380	COG0840	transmembrane signaling receptor activity
ASUIS_RS02390	COG0495	leucyl-tRNA aminoacylation
ASUIS_RS02400	COG0285	dihydrofolate synthase activity
ASUIS_RS02420	COG0848	biopolymer transport protein
ASUIS_RS02440	COG1136	(ABC) transporter
ASUIS_RS02440	COG0577	efflux transmembrane transporter activity
ASUIS_RS02445	COG0577	efflux transmembrane transporter activity
ASUIS_RS02445	COG1136	(ABC) transporter
ASUIS_RS02490	COG0735	belongs to the Fur family
ASUIS_RS02500	COG0114	fumarate hydratase activity
ASUIS_RS02515	COG3852	Histidine kinase
ASUIS_RS02520	COG4753	response regulator
ASUIS_RS02520	COG2207	Transcriptional regulator
ASUIS_RS02545	COG4773	Receptor
ASUIS_RS02580	COG4774	siderophore transport
ASUIS_RS02585	COG3128	pkhd-type hydroxylase
ASUIS_RS02625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASUIS_RS02650	COG5001	Diguanylate cyclase
ASUIS_RS02650	COG4251	negative regulation of phosphorylation
ASUIS_RS02650	COG3706	GGDEF domain
ASUIS_RS02650	COG2203	Gaf domain
ASUIS_RS02660	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS02665	COG0642	Histidine kinase
ASUIS_RS02670	COG2081	HI0933 family
ASUIS_RS02675	COG0840	transmembrane signaling receptor activity
ASUIS_RS02690	COG5000	phosphorelay sensor kinase activity
ASUIS_RS02695	COG1692	metallophosphoesterase
ASUIS_RS02710	COG2226	methyltransferase
ASUIS_RS02715	COG1570	exodeoxyribonuclease VII activity
ASUIS_RS02720	COG0835	chemotaxis
ASUIS_RS02740	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ASUIS_RS02745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASUIS_RS02755	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASUIS_RS02760	COG0459	protein refolding
ASUIS_RS02765	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASUIS_RS02780	COG1408	metallophosphoesterase
ASUIS_RS02805	COG0577	efflux transmembrane transporter activity
ASUIS_RS02805	COG1136	(ABC) transporter
ASUIS_RS02820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASUIS_RS02835	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASUIS_RS02840	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ASUIS_RS02845	COG0352	thiamine-phosphate diphosphorylase activity
ASUIS_RS02850	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASUIS_RS02860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASUIS_RS02865	COG2264	protein methyltransferase activity
ASUIS_RS02875	COG4191	Histidine kinase
ASUIS_RS02880	COG0784	Response regulator, receiver
ASUIS_RS02880	COG3437	response regulator, receiver
ASUIS_RS02890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASUIS_RS02905	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASUIS_RS02950	COG3706	GGDEF domain
ASUIS_RS02955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASUIS_RS02960	COG1090	epimerase
ASUIS_RS02965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASUIS_RS02980	COG0481	GTPase activity
ASUIS_RS02990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASUIS_RS03000	COG0482	sulfurtransferase activity
ASUIS_RS03005	COG0482	sulfurtransferase activity
ASUIS_RS03010	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASUIS_RS03015	COG0006	proline dipeptidase activity
ASUIS_RS03020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASUIS_RS03025	COG0402	S-adenosylhomocysteine deaminase activity
ASUIS_RS03030	COG0616	signal peptide processing
ASUIS_RS03040	COG0280	phosphate acetyltransferase
ASUIS_RS03045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASUIS_RS03050	COG2176	DNA-directed DNA polymerase activity
ASUIS_RS03075	COG3162	membrane
ASUIS_RS03090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASUIS_RS03105	COG5002	protein histidine kinase activity
ASUIS_RS03150	COG1546	Belongs to the CinA family
ASUIS_RS03150	COG1058	Belongs to the CinA family
ASUIS_RS03155	COG0579	oxidoreductase
ASUIS_RS03160	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASUIS_RS03175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASUIS_RS03195	COG0052	Belongs to the universal ribosomal protein uS2 family
ASUIS_RS03200	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASUIS_RS03205	COG1136	(ABC) transporter
ASUIS_RS03215	COG0194	GDP metabolic process
ASUIS_RS03220	COG5001	Diguanylate cyclase
ASUIS_RS03220	COG5002	protein histidine kinase activity
ASUIS_RS03225	COG2217	Heavy metal translocating P-type atpase
ASUIS_RS03240	COG4608	Belongs to the ABC transporter superfamily
ASUIS_RS03245	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASUIS_RS03260	COG1355	regulation of microtubule-based process
ASUIS_RS03270	COG1121	(ABC) transporter
ASUIS_RS03275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASUIS_RS03280	COG2996	Protein conserved in bacteria
ASUIS_RS03285	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ASUIS_RS03290	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ASUIS_RS03300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ASUIS_RS03305	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ASUIS_RS03310	COG0210	DNA helicase
ASUIS_RS03315	COG0475	glutathione-regulated potassium exporter activity
ASUIS_RS03315	COG0569	domain protein
ASUIS_RS03320	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ASUIS_RS03330	COG2010	Cytochrome c
ASUIS_RS03345	COG3258	Cytochrome c
ASUIS_RS03380	COG1414	Transcriptional regulator
ASUIS_RS03385	COG0693	protein deglycase activity
ASUIS_RS03400	COG0525	valine-tRNA ligase activity
ASUIS_RS03425	COG3706	GGDEF domain
ASUIS_RS03435	COG2814	Major facilitator Superfamily
ASUIS_RS03440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASUIS_RS03460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASUIS_RS03465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASUIS_RS03470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASUIS_RS03500	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ASUIS_RS03540	COG0439	Biotin carboxylase
ASUIS_RS03550	COG2166	iron-sulfur cluster assembly
ASUIS_RS03555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASUIS_RS03560	COG0719	Fe-S assembly protein
ASUIS_RS03565	COG0396	ATPase activity
ASUIS_RS03570	COG0719	Fe-S assembly protein
ASUIS_RS03580	COG0822	iron-sulfur transferase activity
ASUIS_RS03580	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ASUIS_RS03580	COG2906	2 iron, 2 sulfur cluster binding
ASUIS_RS03605	COG2239	Acts as a magnesium transporter
ASUIS_RS03620	COG0165	Argininosuccinate lyase
ASUIS_RS03625	COG0784	Response regulator, receiver
ASUIS_RS03625	COG0835	chemotaxis
ASUIS_RS03630	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASUIS_RS03635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASUIS_RS03640	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASUIS_RS03655	COG0556	nucleotide-excision repair
ASUIS_RS03660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASUIS_RS03670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASUIS_RS03685	COG0698	ribose 5-phosphate isomerase
ASUIS_RS03690	COG0681	Belongs to the peptidase S26 family
ASUIS_RS03695	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASUIS_RS03700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASUIS_RS03705	COG0193	aminoacyl-tRNA hydrolase activity
ASUIS_RS03720	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASUIS_RS03730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASUIS_RS03735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASUIS_RS03745	COG0528	UMP kinase activity
ASUIS_RS03755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASUIS_RS03760	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ASUIS_RS03765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASUIS_RS03775	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASUIS_RS03780	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASUIS_RS03795	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASUIS_RS03800	COG0305	Participates in initiation and elongation during chromosome replication
ASUIS_RS03810	COG1793	dna ligase
ASUIS_RS03815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASUIS_RS03820	COG0133	tryptophan synthase activity
ASUIS_RS03830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASUIS_RS04135	COG0457	Tetratricopeptide repeat
ASUIS_RS04135	COG0859	PFAM glycosyl transferase family 9
ASUIS_RS04190	COG1966	Carbon starvation protein
ASUIS_RS04195	COG0012	GTP binding
ASUIS_RS04215	COG3123	guanosine phosphorylase activity
ASUIS_RS04235	COG1979	alcohol dehydrogenase
ASUIS_RS04255	COG2207	Transcriptional regulator
ASUIS_RS04270	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ASUIS_RS04275	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASUIS_RS04280	COG0667	Aldo Keto reductase
ASUIS_RS04290	COG4974	Belongs to the 'phage' integrase family
ASUIS_RS04300	COG3550	peptidyl-serine autophosphorylation
ASUIS_RS04345	COG2205	protein histidine kinase activity
ASUIS_RS04390	COG4974	Belongs to the 'phage' integrase family
ASUIS_RS04415	COG1475	DNA binding
ASUIS_RS04430	COG0489	protein tyrosine kinase activity
ASUIS_RS04485	COG0305	Participates in initiation and elongation during chromosome replication
ASUIS_RS04535	COG0740	serine-type endopeptidase activity
ASUIS_RS04650	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ASUIS_RS04655	COG0585	pseudouridine synthase activity
ASUIS_RS04665	COG0840	transmembrane signaling receptor activity
ASUIS_RS04670	COG0632	four-way junction helicase activity
ASUIS_RS04675	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASUIS_RS04685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASUIS_RS04700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASUIS_RS04795	COG2801	Transposase and inactivated derivatives
ASUIS_RS04810	COG0051	transcription antitermination factor activity, RNA binding
ASUIS_RS04815	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASUIS_RS04820	COG0088	Forms part of the polypeptide exit tunnel
ASUIS_RS04825	COG0089	rRNA binding
ASUIS_RS04830	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASUIS_RS04835	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASUIS_RS04840	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASUIS_RS04845	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASUIS_RS04850	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASUIS_RS04855	COG0255	Belongs to the universal ribosomal protein uL29 family
ASUIS_RS04860	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASUIS_RS04865	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASUIS_RS04870	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASUIS_RS04875	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASUIS_RS04880	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASUIS_RS04885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASUIS_RS04890	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASUIS_RS04895	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASUIS_RS04900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASUIS_RS04905	COG0200	Binds to the 23S rRNA
ASUIS_RS04910	COG0201	protein transport
ASUIS_RS04915	COG0024	Methionine aminopeptidase
ASUIS_RS04920	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASUIS_RS04930	COG1573	uracil-dna glycosylase
ASUIS_RS04940	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASUIS_RS04955	COG1032	radical SAM domain protein
ASUIS_RS04965	COG0563	adenylate kinase activity
ASUIS_RS04975	COG3739	integral membrane protein
ASUIS_RS04990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASUIS_RS04995	COG0322	excinuclease ABC activity
ASUIS_RS05005	COG4565	transcriptional regulatory protein
ASUIS_RS05015	COG3201	nicotinamide mononucleotide transporter
ASUIS_RS05020	COG0386	Belongs to the glutathione peroxidase family
ASUIS_RS05025	COG0840	transmembrane signaling receptor activity
ASUIS_RS05035	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS05045	COG2205	protein histidine kinase activity
ASUIS_RS05045	COG0784	Response regulator, receiver
ASUIS_RS05055	COG4773	Receptor
ASUIS_RS05085	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ASUIS_RS05095	COG0829	nickel cation binding
ASUIS_RS05100	COG0831	urea catabolic process
ASUIS_RS05100	COG0832	Belongs to the urease beta subunit family
ASUIS_RS05105	COG0804	urea catabolic process
ASUIS_RS05110	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ASUIS_RS05120	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ASUIS_RS05125	COG2204	response regulator
ASUIS_RS05150	COG0840	transmembrane signaling receptor activity
ASUIS_RS05160	COG1921	L-seryl-tRNASec selenium transferase activity
ASUIS_RS05175	COG0709	Synthesizes selenophosphate from selenide and ATP
ASUIS_RS05180	COG1305	Transglutaminase-like
ASUIS_RS05195	COG4565	transcriptional regulatory protein
ASUIS_RS05230	COG0437	4 iron, 4 sulfur cluster binding
ASUIS_RS05240	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASUIS_RS05260	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASUIS_RS05270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASUIS_RS05275	COG0306	phosphate transporter
ASUIS_RS05285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASUIS_RS05290	COG0328	RNA-DNA hybrid ribonuclease activity
ASUIS_RS05295	COG0840	transmembrane signaling receptor activity
ASUIS_RS05310	COG1960	acyl-CoA dehydrogenase activity
ASUIS_RS05330	COG1944	ATP diphosphatase activity
ASUIS_RS05340	COG0861	Integral membrane protein TerC family
ASUIS_RS05360	COG0513	Belongs to the DEAD box helicase family
ASUIS_RS05375	COG2258	MOSC domain
ASUIS_RS05380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASUIS_RS05390	COG3135	benzoate transporter
ASUIS_RS05400	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASUIS_RS05410	COG0475	glutathione-regulated potassium exporter activity
ASUIS_RS05410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASUIS_RS05510	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASUIS_RS05515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASUIS_RS05515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASUIS_RS05535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASUIS_RS05555	COG2853	Lipoprotein
ASUIS_RS05560	COG0217	transcriptional regulatory protein
ASUIS_RS05570	COG1960	acyl-CoA dehydrogenase activity
ASUIS_RS05575	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASUIS_RS05575	COG1024	Enoyl-CoA hydratase
ASUIS_RS05580	COG0183	Belongs to the thiolase family
ASUIS_RS05585	COG1022	Amp-dependent synthetase and ligase
ASUIS_RS05595	COG0242	peptide deformylase activity
ASUIS_RS05605	COG1049	propionate catabolic process, 2-methylcitrate cycle
ASUIS_RS05620	COG2199	diguanylate cyclase activity
ASUIS_RS05620	COG2203	Gaf domain
ASUIS_RS05625	COG1309	transcriptional regulator
ASUIS_RS05630	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ASUIS_RS05635	COG3259	Nickel-dependent hydrogenase
ASUIS_RS05640	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ASUIS_RS05645	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ASUIS_RS05670	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ASUIS_RS05675	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ASUIS_RS05680	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ASUIS_RS05685	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ASUIS_RS05690	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ASUIS_RS05695	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ASUIS_RS05715	COG3383	formate dehydrogenase (NAD+) activity
ASUIS_RS05750	COG3263	regulation of cellular component size
ASUIS_RS05765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASUIS_RS05765	COG0301	tRNA thio-modification
ASUIS_RS05785	COG0596	Alpha beta hydrolase
ASUIS_RS05790	COG0384	phenazine biosynthesis protein PhzF
ASUIS_RS05800	COG2814	Major facilitator Superfamily
ASUIS_RS05820	COG2354	Protein conserved in bacteria
ASUIS_RS05830	COG2081	HI0933 family
ASUIS_RS05845	COG0840	transmembrane signaling receptor activity
ASUIS_RS05855	COG0310	cobalt ion transport
ASUIS_RS05875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ASUIS_RS05885	COG4191	Histidine kinase
ASUIS_RS05900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ASUIS_RS05905	COG0298	carbon dioxide binding
ASUIS_RS05910	COG0409	Hydrogenase expression formation protein
ASUIS_RS05915	COG2084	Dehydrogenase
ASUIS_RS05925	COG1401	restriction endodeoxyribonuclease activity
ASUIS_RS05925	COG1401	restriction endodeoxyribonuclease activity
ASUIS_RS05935	COG0309	Hydrogenase expression formation protein (HypE)
ASUIS_RS05945	COG3706	GGDEF domain
ASUIS_RS05970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASUIS_RS05975	COG2171	N-acyltransferase activity
ASUIS_RS05980	COG0488	(ABC) transporter
ASUIS_RS05990	COG1671	Belongs to the UPF0178 family
ASUIS_RS06005	COG2884	Cell division ATP-binding protein ftsE
ASUIS_RS06010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASUIS_RS06020	COG0564	pseudouridine synthase activity
ASUIS_RS06025	COG0772	Belongs to the SEDS family
ASUIS_RS06040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASUIS_RS06065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASUIS_RS06070	COG0066	3-isopropylmalate dehydratase activity
ASUIS_RS06075	COG0473	3-isopropylmalate dehydrogenase activity
ASUIS_RS06090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASUIS_RS06095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASUIS_RS06100	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASUIS_RS06105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASUIS_RS06110	COG0202	RNA polymerase activity
ASUIS_RS06115	COG0203	ribosomal protein L17
ASUIS_RS06120	COG0154	amidase activity
ASUIS_RS06125	COG0517	IMP dehydrogenase activity
ASUIS_RS06125	COG0516	GMP reductase activity
ASUIS_RS06170	COG0484	heat shock protein binding
ASUIS_RS06190	COG1472	Belongs to the glycosyl hydrolase 3 family
ASUIS_RS06195	COG1132	(ABC) transporter
ASUIS_RS06210	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS06215	COG0642	Histidine kinase
ASUIS_RS06230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASUIS_RS06245	COG0415	Belongs to the DNA photolyase family
ASUIS_RS06260	COG3275	phosphorelay sensor kinase activity
ASUIS_RS06265	COG3279	Response regulator of the LytR AlgR family
ASUIS_RS06275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASUIS_RS06280	COG0513	Belongs to the DEAD box helicase family
ASUIS_RS06285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASUIS_RS06295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASUIS_RS06300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASUIS_RS06310	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASUIS_RS06325	COG4774	siderophore transport
ASUIS_RS06330	COG1193	negative regulation of DNA recombination
ASUIS_RS06345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASUIS_RS06360	COG1396	sequence-specific DNA binding
ASUIS_RS06370	COG0789	Transcriptional regulator
ASUIS_RS06375	COG0484	heat shock protein binding
ASUIS_RS06390	COG2201	protein-glutamate methylesterase activity
ASUIS_RS06410	COG1388	LysM domain
ASUIS_RS06410	COG1376	ErfK ybiS ycfS ynhG family protein
ASUIS_RS06425	COG0776	regulation of translation
ASUIS_RS06435	COG0275	rRNA processing
ASUIS_RS06470	COG4865	methylaspartate mutase activity
ASUIS_RS06490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASUIS_RS06500	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASUIS_RS06505	COG0653	protein targeting
ASUIS_RS06535	COG0754	glutathionylspermidine amidase activity
ASUIS_RS06545	COG0840	transmembrane signaling receptor activity
ASUIS_RS06550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASUIS_RS06555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASUIS_RS06565	COG0788	formyltetrahydrofolate deformylase activity
ASUIS_RS06570	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASUIS_RS06575	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS06590	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ASUIS_RS06605	COG0811	peptide transport
ASUIS_RS06610	COG0848	biopolymer transport protein
ASUIS_RS06625	COG0419	ATPase involved in DNA repair
ASUIS_RS06635	COG2801	Transposase and inactivated derivatives
ASUIS_RS06670	COG0028	Belongs to the TPP enzyme family
ASUIS_RS06675	COG0440	acetolactate synthase activity
ASUIS_RS06680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASUIS_RS06685	COG1674	ftsk spoiiie
ASUIS_RS06685	COG1196	nuclear chromosome segregation
ASUIS_RS06690	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS06695	COG0642	Histidine kinase
ASUIS_RS06705	COG1749	Flagellar hook protein flgE
ASUIS_RS06725	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASUIS_RS06740	COG1160	GTP binding
ASUIS_RS06745	COG0659	secondary active sulfate transmembrane transporter activity
ASUIS_RS06765	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASUIS_RS06775	COG1185	polyribonucleotide nucleotidyltransferase activity
ASUIS_RS06785	COG2198	Histidine kinase
ASUIS_RS06785	COG0643	Histidine kinase
ASUIS_RS06790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASUIS_RS06795	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ASUIS_RS06800	COG2201	protein-glutamate methylesterase activity
ASUIS_RS06805	COG2223	nitrite transmembrane transporter activity
ASUIS_RS06810	COG0582	viral genome integration into host DNA
ASUIS_RS06830	COG0339	signal peptide processing
ASUIS_RS06835	COG2890	protein-(glutamine-N5) methyltransferase activity
ASUIS_RS06840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASUIS_RS06845	COG0494	nUDIX hydrolase
ASUIS_RS06850	COG0527	aspartate kinase activity
ASUIS_RS06865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASUIS_RS06870	COG0287	Prephenate dehydrogenase
ASUIS_RS06875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASUIS_RS06880	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ASUIS_RS06885	COG0612	Peptidase, M16
ASUIS_RS06890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASUIS_RS06915	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ASUIS_RS06925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASUIS_RS06925	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASUIS_RS06940	COG3630	sodium ion export across plasma membrane
ASUIS_RS06945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASUIS_RS06955	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ASUIS_RS07010	COG0357	Ribosomal RNA small subunit methyltransferase G
ASUIS_RS07015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASUIS_RS07020	COG0113	porphobilinogen synthase activity
ASUIS_RS07035	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS07050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASUIS_RS07050	COG1328	CTP reductase activity
ASUIS_RS07055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASUIS_RS07060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASUIS_RS07070	COG1663	tetraacyldisaccharide 4'-kinase activity
ASUIS_RS07080	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASUIS_RS07100	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASUIS_RS07105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASUIS_RS07110	COG0805	protein transport
ASUIS_RS07115	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASUIS_RS07155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASUIS_RS07165	COG2181	nitrate reductase activity
ASUIS_RS07165	COG0247	lactate metabolic process
ASUIS_RS07170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASUIS_RS07190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASUIS_RS07190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASUIS_RS07195	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASUIS_RS07200	COG2199	diguanylate cyclase activity
ASUIS_RS07200	COG2200	EAL domain
ASUIS_RS07200	COG3287	FIST C domain
ASUIS_RS07210	COG1137	ATPase activity
ASUIS_RS07215	COG0802	atpase or kinase
ASUIS_RS07220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASUIS_RS07230	COG0137	argininosuccinate synthase activity
ASUIS_RS07240	COG0569	domain protein
ASUIS_RS07245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASUIS_RS07250	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS07255	COG2205	protein histidine kinase activity
ASUIS_RS07265	COG0840	transmembrane signaling receptor activity
ASUIS_RS07275	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASUIS_RS07280	COG0484	heat shock protein binding
ASUIS_RS07285	COG0133	tryptophan synthase activity
ASUIS_RS07305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASUIS_RS07310	COG5001	Diguanylate cyclase
ASUIS_RS07315	COG2203	Gaf domain
ASUIS_RS07315	COG5001	Diguanylate cyclase
ASUIS_RS07315	COG4251	negative regulation of phosphorylation
ASUIS_RS07315	COG3706	GGDEF domain
ASUIS_RS07320	COG0500	methyltransferase
ASUIS_RS07325	COG1333	cytochrome c biogenesis protein
ASUIS_RS07325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASUIS_RS07330	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASUIS_RS07345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASUIS_RS07365	COG3706	GGDEF domain
ASUIS_RS07365	COG4251	negative regulation of phosphorylation
ASUIS_RS07365	COG2203	Gaf domain
ASUIS_RS07365	COG5001	Diguanylate cyclase
ASUIS_RS07385	COG0037	tRNA processing
ASUIS_RS07405	COG1322	Protein conserved in bacteria
ASUIS_RS07410	COG0501	Belongs to the peptidase M48B family
ASUIS_RS07420	COG0824	Thioesterase
ASUIS_RS07430	COG0840	transmembrane signaling receptor activity
ASUIS_RS07435	COG0667	Aldo Keto reductase
ASUIS_RS07455	COG4822	anaerobic cobalamin biosynthetic process
ASUIS_RS07465	COG1797	cobyrinic acid a,c-diamide synthase activity
ASUIS_RS07510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASUIS_RS07525	COG4206	TonB-dependent receptor
ASUIS_RS07545	COG0546	phosphoglycolate phosphatase activity
ASUIS_RS07550	COG1187	pseudouridine synthase activity
ASUIS_RS07555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ASUIS_RS07560	COG1607	acyl-coa hydrolase
ASUIS_RS07565	COG0488	(ABC) transporter
ASUIS_RS07575	COG0300	oxidoreductase activity
ASUIS_RS07580	COG2211	Major facilitator Superfamily
ASUIS_RS07585	COG3040	lipid binding
ASUIS_RS07600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASUIS_RS07610	COG2200	EAL domain
ASUIS_RS07610	COG2199	diguanylate cyclase activity
ASUIS_RS07610	COG3287	FIST C domain
ASUIS_RS07615	COG3706	GGDEF domain
ASUIS_RS07620	COG3046	protein related to deoxyribodipyrimidine photolyase
ASUIS_RS07635	COG3040	lipid binding
ASUIS_RS07650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASUIS_RS07655	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ASUIS_RS07660	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS07665	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS07675	COG0840	transmembrane signaling receptor activity
ASUIS_RS07680	COG0643	Histidine kinase
ASUIS_RS07680	COG2198	Histidine kinase
ASUIS_RS07690	COG0840	transmembrane signaling receptor activity
ASUIS_RS07695	COG0840	transmembrane signaling receptor activity
ASUIS_RS07700	COG0840	transmembrane signaling receptor activity
ASUIS_RS07730	COG3852	Histidine kinase
ASUIS_RS07735	COG0778	Nitroreductase
ASUIS_RS07745	COG1902	pentaerythritol trinitrate reductase activity
ASUIS_RS07755	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASUIS_RS07760	COG1733	regulation of RNA biosynthetic process
ASUIS_RS07775	COG2855	membrane
ASUIS_RS07780	COG0583	DNA-binding transcription factor activity
ASUIS_RS07785	COG1881	PFAM PEBP family protein
ASUIS_RS07795	COG2203	Gaf domain
ASUIS_RS07795	COG3706	GGDEF domain
ASUIS_RS07795	COG4251	negative regulation of phosphorylation
ASUIS_RS07795	COG5001	Diguanylate cyclase
ASUIS_RS07810	COG2076	Multidrug Resistance protein
ASUIS_RS07820	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASUIS_RS07825	COG1733	regulation of RNA biosynthetic process
ASUIS_RS07850	COG2824	Alkylphosphonate utilization operon protein PhnA
ASUIS_RS07865	COG0596	Alpha beta hydrolase
ASUIS_RS07890	COG0454	-acetyltransferase
ASUIS_RS07895	COG1605	Chorismate mutase
ASUIS_RS07895	COG0077	Prephenate dehydratase
ASUIS_RS07910	COG1119	ATPase activity
ASUIS_RS07925	COG4974	Belongs to the 'phage' integrase family
ASUIS_RS08000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASUIS_RS08005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASUIS_RS08010	COG1722	exodeoxyribonuclease VII activity
ASUIS_RS08015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASUIS_RS08040	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASUIS_RS08045	COG0849	cell division
ASUIS_RS08095	COG0768	penicillin binding
ASUIS_RS08100	COG1338	Plays a role in the flagellum-specific transport system
ASUIS_RS08110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASUIS_RS08155	COG0456	acetyltransferase
ASUIS_RS08160	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASUIS_RS08175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ASUIS_RS08180	COG0131	Imidazoleglycerol-phosphate dehydratase
ASUIS_RS08185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASUIS_RS08195	COG0084	hydrolase, TatD family'
ASUIS_RS08205	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASUIS_RS08210	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASUIS_RS08215	COG0359	binds to the 23S rRNA
ASUIS_RS08225	COG0163	prenyltransferase activity
ASUIS_RS08230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASUIS_RS08235	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASUIS_RS08240	COG0124	histidyl-tRNA synthetase
ASUIS_RS08245	COG1166	arginine decarboxylase activity
ASUIS_RS08250	COG1045	serine acetyltransferase
ASUIS_RS08260	COG0513	Belongs to the DEAD box helicase family
ASUIS_RS08265	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASUIS_RS08275	COG1309	transcriptional regulator
ASUIS_RS08295	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASUIS_RS08320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASUIS_RS08335	COG1253	flavin adenine dinucleotide binding
ASUIS_RS08350	COG1280	lysine exporter protein (LysE YggA)
ASUIS_RS08360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASUIS_RS08365	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASUIS_RS08370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASUIS_RS08375	COG0095	Lipoate-protein ligase
ASUIS_RS08380	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASUIS_RS08385	COG0039	L-malate dehydrogenase activity
ASUIS_RS08390	COG0628	permease
ASUIS_RS08400	COG2989	Protein conserved in bacteria
ASUIS_RS08405	COG1253	flavin adenine dinucleotide binding
ASUIS_RS08435	COG1028	Short-chain dehydrogenase reductase Sdr
ASUIS_RS08440	COG2807	transmembrane transport
ASUIS_RS08445	COG2186	Transcriptional regulator
ASUIS_RS08450	COG2223	nitrite transmembrane transporter activity
ASUIS_RS08455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASUIS_RS08460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASUIS_RS08490	COG0564	pseudouridine synthase activity
ASUIS_RS08550	COG1187	pseudouridine synthase activity
ASUIS_RS08580	COG0454	-acetyltransferase
ASUIS_RS08595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASUIS_RS08595	COG0519	Catalyzes the synthesis of GMP from XMP
ASUIS_RS08600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASUIS_RS08605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ASUIS_RS08615	COG1451	nucleotide metabolic process
ASUIS_RS08620	COG0436	Aminotransferase
ASUIS_RS08635	COG0488	(ABC) transporter
ASUIS_RS08640	COG1610	YqeY-like protein
ASUIS_RS08655	COG5002	protein histidine kinase activity
ASUIS_RS08670	COG3258	Cytochrome c
ASUIS_RS08690	COG0300	oxidoreductase activity
ASUIS_RS08695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASUIS_RS08700	COG0742	ribosomal rna small subunit methyltransferase
ASUIS_RS08705	COG1418	mRNA catabolic process
ASUIS_RS08715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASUIS_RS08720	COG0552	protein localization to endoplasmic reticulum
ASUIS_RS08765	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASUIS_RS08770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASUIS_RS08780	COG1592	Rubrerythrin
ASUIS_RS08790	COG0728	peptidoglycan biosynthetic process
ASUIS_RS08795	COG1132	(ABC) transporter
ASUIS_RS08800	COG0167	dihydroorotate dehydrogenase activity
ASUIS_RS08815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASUIS_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
ASUIS_RS08825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASUIS_RS08830	COG0750	zinc metalloprotease
ASUIS_RS08835	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASUIS_RS08840	COG1942	4-Oxalocrotonate Tautomerase
ASUIS_RS08850	COG0583	DNA-binding transcription factor activity
ASUIS_RS08855	COG0134	indole-3-glycerol-phosphate synthase activity
ASUIS_RS08865	COG0727	PFAM Uncharacterised protein family (UPF0153)
ASUIS_RS08870	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ASUIS_RS08880	COG0674	pyruvate-flavodoxin oxidoreductase activity
ASUIS_RS08880	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ASUIS_RS08885	COG1013	pyruvate-flavodoxin oxidoreductase activity
ASUIS_RS08900	COG2176	DNA-directed DNA polymerase activity
ASUIS_RS08905	COG0135	phosphoribosylanthranilate isomerase activity
ASUIS_RS08910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASUIS_RS08930	COG0642	Histidine kinase
ASUIS_RS08935	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS08940	COG1666	GTP binding
ASUIS_RS08945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASUIS_RS08955	COG2363	Small membrane protein
ASUIS_RS08960	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ASUIS_RS08995	COG0166	Belongs to the GPI family
ASUIS_RS09010	COG0531	amino acid
ASUIS_RS09040	COG0708	Exodeoxyribonuclease III
ASUIS_RS09050	COG1846	Transcriptional regulator
ASUIS_RS09075	COG2205	protein histidine kinase activity
ASUIS_RS09075	COG3850	Histidine kinase
ASUIS_RS09075	COG3437	response regulator, receiver
ASUIS_RS09075	COG4999	Histidine kinase
ASUIS_RS09100	COG0582	viral genome integration into host DNA
ASUIS_RS09135	COG4191	Histidine kinase
ASUIS_RS09145	COG3287	FIST C domain
ASUIS_RS09145	COG2200	EAL domain
ASUIS_RS09145	COG2199	diguanylate cyclase activity
ASUIS_RS09150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASUIS_RS09160	COG1078	dGTPase activity
ASUIS_RS09165	COG0259	pyridoxamine-phosphate oxidase activity
ASUIS_RS09175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASUIS_RS09185	COG0513	Belongs to the DEAD box helicase family
ASUIS_RS09200	COG2199	diguanylate cyclase activity
ASUIS_RS09200	COG2200	EAL domain
ASUIS_RS09200	COG3287	FIST C domain
ASUIS_RS09210	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ASUIS_RS09240	COG0326	Molecular chaperone. Has ATPase activity
ASUIS_RS09255	COG0753	catalase activity
ASUIS_RS09265	COG2995	paraquat-inducible protein a
ASUIS_RS09280	COG5001	Diguanylate cyclase
ASUIS_RS09280	COG5002	protein histidine kinase activity
ASUIS_RS09300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASUIS_RS09305	COG0716	FMN binding
ASUIS_RS09315	COG4335	DNA alkylation repair
ASUIS_RS09345	COG0010	Belongs to the arginase family
ASUIS_RS09350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASUIS_RS09355	COG2207	Transcriptional regulator
ASUIS_RS09360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASUIS_RS09370	COG1227	inorganic diphosphatase activity
ASUIS_RS09400	COG1027	Aspartate ammonia-lyase
ASUIS_RS09405	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS09415	COG1115	amino acid carrier protein
ASUIS_RS09420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASUIS_RS09425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASUIS_RS09430	COG1047	Peptidyl-prolyl cis-trans
ASUIS_RS09445	COG0823	Involved in the tonB-independent uptake of proteins
ASUIS_RS09455	COG0848	biopolymer transport protein
ASUIS_RS09460	COG0811	peptide transport
ASUIS_RS09465	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASUIS_RS09470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASUIS_RS09475	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASUIS_RS09480	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASUIS_RS09485	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASUIS_RS09490	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASUIS_RS09500	COG1475	DNA binding
ASUIS_RS09505	COG1192	Involved in chromosome partitioning
ASUIS_RS09510	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ASUIS_RS09510	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ASUIS_RS09520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASUIS_RS09525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASUIS_RS09530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASUIS_RS09535	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASUIS_RS09540	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASUIS_RS09545	COG0251	oxidation-reduction process
ASUIS_RS09550	COG0358	DNA primase activity
ASUIS_RS09555	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASUIS_RS09560	COG0571	ribonuclease III activity
ASUIS_RS09565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASUIS_RS09575	COG1686	Belongs to the peptidase S11 family
ASUIS_RS09580	COG0501	Belongs to the peptidase M48B family
ASUIS_RS09600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASUIS_RS09610	COG0706	membrane insertase activity
ASUIS_RS09615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASUIS_RS09630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASUIS_RS09635	COG0542	response to heat
ASUIS_RS09650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASUIS_RS09665	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASUIS_RS09675	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASUIS_RS09680	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS09685	COG3437	response regulator, receiver
ASUIS_RS09695	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASUIS_RS09700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASUIS_RS09700	COG0730	response to heat
ASUIS_RS09730	COG0138	bifunctional purine biosynthesis protein purh
ASUIS_RS09735	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASUIS_RS09745	COG0739	heme binding
ASUIS_RS09750	COG0302	gtp cyclohydrolase
ASUIS_RS09755	COG0598	Magnesium transport protein CorA
ASUIS_RS09760	COG1459	type II secretion system
ASUIS_RS09780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASUIS_RS09785	COG0606	chelatase, subunit chli
ASUIS_RS09795	COG0840	transmembrane signaling receptor activity
ASUIS_RS09805	COG0242	peptide deformylase activity
ASUIS_RS09810	COG0740	serine-type endopeptidase activity
ASUIS_RS09815	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASUIS_RS09820	COG2326	polyphosphate kinase activity
ASUIS_RS09850	COG0582	viral genome integration into host DNA
ASUIS_RS09860	COG2801	Transposase and inactivated derivatives
ASUIS_RS09880	COG2801	Transposase and inactivated derivatives
ASUIS_RS09925	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS09935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASUIS_RS09940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASUIS_RS09940	COG1648	precorrin-2 dehydrogenase activity
ASUIS_RS09945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASUIS_RS09970	COG3278	Belongs to the heme-copper respiratory oxidase family
ASUIS_RS09995	COG4681	YaeQ
ASUIS_RS10005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASUIS_RS10010	COG1696	Membrane protein involved in D-alanine export
ASUIS_RS10020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASUIS_RS10025	COG0626	cystathionine gamma-synthase activity
ASUIS_RS10035	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS10045	COG0840	transmembrane signaling receptor activity
ASUIS_RS10050	COG0840	transmembrane signaling receptor activity
ASUIS_RS10055	COG0840	transmembrane signaling receptor activity
ASUIS_RS10060	COG0840	transmembrane signaling receptor activity
ASUIS_RS10070	COG3437	response regulator, receiver
ASUIS_RS10070	COG0784	Response regulator, receiver
ASUIS_RS10080	COG2198	Histidine kinase
ASUIS_RS10080	COG0643	Histidine kinase
ASUIS_RS10105	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS10115	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ASUIS_RS10130	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASUIS_RS10135	COG1917	Cupin 2, conserved barrel domain protein
ASUIS_RS10135	COG2207	Transcriptional regulator
ASUIS_RS10145	COG1301	dicarboxylic acid transport
ASUIS_RS10150	COG1028	Short-chain dehydrogenase reductase Sdr
ASUIS_RS10160	COG2199	diguanylate cyclase activity
ASUIS_RS10160	COG3287	FIST C domain
ASUIS_RS10160	COG2200	EAL domain
ASUIS_RS10170	COG0628	permease
ASUIS_RS10180	COG1858	cytochrome C peroxidase
ASUIS_RS10210	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASUIS_RS10225	COG1086	Polysaccharide biosynthesis protein
ASUIS_RS10235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASUIS_RS10240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASUIS_RS10310	COG0367	asparagine synthase
ASUIS_RS10340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASUIS_RS10350	COG0529	Catalyzes the synthesis of activated sulfate
ASUIS_RS10360	COG0471	metal ion transport
ASUIS_RS10360	COG3273	potassium ion transport
ASUIS_RS10370	COG0455	bacterial-type flagellum organization
ASUIS_RS10390	COG2801	Transposase and inactivated derivatives
ASUIS_RS10410	COG0351	phosphomethylpyrimidine kinase
ASUIS_RS10420	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASUIS_RS10435	COG0348	domain, Protein
ASUIS_RS10440	COG4191	Histidine kinase
ASUIS_RS10445	COG2207	Transcriptional regulator
ASUIS_RS10445	COG4753	response regulator
ASUIS_RS10460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASUIS_RS10485	COG0716	FMN binding
ASUIS_RS10535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASUIS_RS10565	COG0731	radical SAM domain protein
ASUIS_RS10570	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASUIS_RS10580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASUIS_RS10615	COG0582	viral genome integration into host DNA
ASUIS_RS10625	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ASUIS_RS10635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASUIS_RS10645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASUIS_RS10650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASUIS_RS10655	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ASUIS_RS10655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ASUIS_RS10660	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASUIS_RS10675	COG1215	transferase activity, transferring glycosyl groups
ASUIS_RS10740	COG0297	glycogen (starch) synthase activity
ASUIS_RS10745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASUIS_RS10765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASUIS_RS10775	COG0493	'glutamate synthase
ASUIS_RS10780	COG0070	glutamate synthase
ASUIS_RS10780	COG0067	glutamate synthase
ASUIS_RS10780	COG0069	glutamate synthase activity
ASUIS_RS10785	COG0584	glycerophosphoryl diester phosphodiesterase
ASUIS_RS10805	COG0840	transmembrane signaling receptor activity
ASUIS_RS10865	COG0284	orotidine-5'-phosphate decarboxylase activity
ASUIS_RS10870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASUIS_RS10875	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASUIS_RS10880	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ASUIS_RS10900	COG0697	spore germination
ASUIS_RS10905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASUIS_RS10940	COG1739	Uncharacterized protein family UPF0029
ASUIS_RS10955	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ASUIS_RS10960	COG0196	riboflavin kinase activity
ASUIS_RS10965	COG2226	methyltransferase
ASUIS_RS10970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASUIS_RS10980	COG0277	FAD linked oxidase domain protein
ASUIS_RS11025	COG0542	response to heat
ASUIS_RS11030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ASUIS_RS11035	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASUIS_RS11045	COG0318	PFAM AMP-dependent synthetase and ligase
ASUIS_RS11050	COG2030	dehydratase
ASUIS_RS11075	COG1970	mechanosensitive ion channel activity
ASUIS_RS11080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASUIS_RS11100	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASUIS_RS11105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASUIS_RS11110	COG1157	protein secretion by the type III secretion system
ASUIS_RS11120	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASUIS_RS11140	COG1677	Flagellar hook-basal body complex protein FliE
ASUIS_RS11150	COG0455	bacterial-type flagellum organization
ASUIS_RS11155	COG1419	protein localization to endoplasmic reticulum
ASUIS_RS11195	COG1749	Flagellar hook protein flgE
ASUIS_RS11210	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASUIS_RS11220	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASUIS_RS11225	COG1766	The M ring may be actively involved in energy transduction
ASUIS_RS11230	COG1815	bacterial-type flagellum-dependent cell motility
ASUIS_RS11235	COG4786	Flagellar basal body rod
ASUIS_RS11245	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS11265	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASUIS_RS11270	COG1837	Belongs to the UPF0109 family
ASUIS_RS11275	COG0228	four-way junction DNA binding
ASUIS_RS11280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASUIS_RS11285	COG0564	pseudouridine synthase activity
ASUIS_RS11290	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASUIS_RS11290	COG1519	Transferase
ASUIS_RS11300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASUIS_RS11305	COG0752	glycyl-tRNA synthetase alpha subunit
ASUIS_RS11315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASUIS_RS11325	COG0826	peptidase U32
ASUIS_RS11330	COG0840	transmembrane signaling receptor activity
ASUIS_RS11330	COG0840	transmembrane signaling receptor activity
ASUIS_RS11335	COG0497	DNA recombination
ASUIS_RS11340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASUIS_RS11345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASUIS_RS11350	COG0049	tRNA binding
ASUIS_RS11355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASUIS_RS11360	COG2814	Major facilitator Superfamily
ASUIS_RS11375	COG4895	conserved protein (DUF2196)
ASUIS_RS11385	COG0840	transmembrane signaling receptor activity
ASUIS_RS11395	COG1086	Polysaccharide biosynthesis protein
ASUIS_RS11420	COG1360	Flagellar Motor Protein
ASUIS_RS11425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ASUIS_RS11430	COG0004	ammonium transporteR
ASUIS_RS11435	COG0347	Belongs to the P(II) protein family
ASUIS_RS11440	COG1309	transcriptional regulator
ASUIS_RS11480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASUIS_RS11485	COG0085	RNA polymerase activity
ASUIS_RS11490	COG0222	ribosome binding
ASUIS_RS11495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASUIS_RS11500	COG0081	regulation of translation
ASUIS_RS11505	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASUIS_RS11510	COG0250	Participates in transcription elongation, termination and antitermination
ASUIS_RS11525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASUIS_RS11530	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASUIS_RS11560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASUIS_RS11565	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ASUIS_RS11570	COG0444	Belongs to the ABC transporter superfamily
ASUIS_RS11580	COG0174	glutamine synthetase
ASUIS_RS11590	COG0314	molybdopterin synthase activity
ASUIS_RS11600	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ASUIS_RS11605	COG1968	undecaprenyl-diphosphatase activity
ASUIS_RS11615	COG0772	Belongs to the SEDS family
ASUIS_RS11620	COG0768	penicillin binding
ASUIS_RS11625	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASUIS_RS11675	COG0512	Glutamine amidotransferase of anthranilate synthase
ASUIS_RS11680	COG1840	ABC-type Fe3 transport system, periplasmic component
ASUIS_RS11690	COG3842	ATPase activity
ASUIS_RS11695	COG3706	GGDEF domain
ASUIS_RS11730	COG2183	response to ionizing radiation
ASUIS_RS11745	COG3287	FIST C domain
ASUIS_RS11745	COG2199	diguanylate cyclase activity
ASUIS_RS11745	COG2200	EAL domain
ASUIS_RS11750	COG0251	oxidation-reduction process
ASUIS_RS11775	COG0586	Pfam SNARE associated Golgi protein
ASUIS_RS11785	COG0335	large ribosomal subunit rRNA binding
ASUIS_RS11790	COG0336	Belongs to the RNA methyltransferase TrmD family
ASUIS_RS11800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASUIS_RS11805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASUIS_RS11810	COG0356	it plays a direct role in the translocation of protons across the membrane
ASUIS_RS11820	COG1074	ATP-dependent DNA helicase activity
ASUIS_RS11825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASUIS_RS11830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASUIS_RS11840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASUIS_RS11855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASUIS_RS11865	COG0303	'Molybdopterin
ASUIS_RS11870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ASUIS_RS11880	COG0602	queuosine metabolic process
ASUIS_RS11890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASUIS_RS11900	COG0825	malonyl-CoA metabolic process
ASUIS_RS11905	COG0537	adenosine 5'-monophosphoramidase activity
ASUIS_RS11910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASUIS_RS11915	COG0072	phenylalanine-tRNA ligase activity
ASUIS_RS11915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASUIS_RS11920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASUIS_RS11925	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASUIS_RS11930	COG1185	polyribonucleotide nucleotidyltransferase activity
ASUIS_RS11930	COG0539	negative regulation of cytoplasmic translation
ASUIS_RS11935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASUIS_RS11940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASUIS_RS11945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASUIS_RS11945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASUIS_RS11950	COG0779	Required for maturation of 30S ribosomal subunits
ASUIS_RS11955	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASUIS_RS11960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASUIS_RS11970	COG0083	homoserine kinase activity
ASUIS_RS11980	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASUIS_RS11990	COG2404	hydrolase activity, acting on ester bonds
ASUIS_RS11995	COG0157	Belongs to the NadC ModD family
ASUIS_RS12005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASUIS_RS12015	COG4773	Receptor
ASUIS_RS12025	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASUIS_RS12065	COG3278	Belongs to the heme-copper respiratory oxidase family
ASUIS_RS12070	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASUIS_RS12075	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASUIS_RS12080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASUIS_RS12085	COG0210	DNA helicase
ASUIS_RS12095	COG1242	4 iron, 4 sulfur cluster binding
ASUIS_RS12100	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASUIS_RS12105	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASUIS_RS12110	COG0492	ferredoxin-NADP+ reductase activity
ASUIS_RS12115	COG3118	belongs to the thioredoxin family
ASUIS_RS12120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASUIS_RS12140	COG0791	NLP P60 protein
ASUIS_RS12145	COG0791	NLP P60 protein
ASUIS_RS12160	COG0424	maF-like protein
ASUIS_RS12175	COG4585	Histidine kinase
ASUIS_RS12180	COG0424	maF-like protein
ASUIS_RS12215	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASUIS_RS12220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASUIS_RS12225	COG0077	Prephenate dehydratase
ASUIS_RS12225	COG1605	Chorismate mutase
ASUIS_RS12230	COG0019	diaminopimelate decarboxylase activity
ASUIS_RS12235	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASUIS_RS12240	COG0149	triose-phosphate isomerase activity
ASUIS_RS12245	COG0126	phosphoglycerate kinase activity
ASUIS_RS12255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASUIS_RS12265	COG0018	arginyl-trna synthetase
ASUIS_RS12270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASUIS_RS12275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASUIS_RS12280	COG0204	Acyl-transferase
ASUIS_RS12290	COG0047	phosphoribosylformylglycinamidine synthase activity
ASUIS_RS12295	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASUIS_RS12300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASUIS_RS12305	COG0793	Belongs to the peptidase S41A family
ASUIS_RS12320	COG0585	pseudouridine synthase activity
ASUIS_RS12325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASUIS_RS12335	COG0577	efflux transmembrane transporter activity
ASUIS_RS12335	COG1136	(ABC) transporter
ASUIS_RS12350	COG0861	Integral membrane protein TerC family
ASUIS_RS12370	COG0129	dihydroxy-acid dehydratase activity
ASUIS_RS12380	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS12385	COG0642	Histidine kinase
ASUIS_RS12400	COG0702	epimerase
ASUIS_RS12405	COG1492	cobalamin metabolic process
ASUIS_RS12425	COG4771	TonB-dependent receptor
ASUIS_RS12435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASUIS_RS12440	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ASUIS_RS12450	COG2095	MarC family integral membrane protein
ASUIS_RS12455	COG2755	lipolytic protein G-D-S-L family
ASUIS_RS12455	COG1083	cytidylyl-transferase
ASUIS_RS12460	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ASUIS_RS12490	COG0189	ligase activity
ASUIS_RS12505	COG3287	FIST C domain
ASUIS_RS12505	COG2200	EAL domain
ASUIS_RS12505	COG2199	diguanylate cyclase activity
ASUIS_RS12510	COG0688	phosphatidylethanolamine metabolic process
ASUIS_RS12520	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ASUIS_RS12530	COG0443	Heat shock 70 kDa protein
ASUIS_RS12535	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASUIS_RS12550	COG0101	tRNA pseudouridine synthase activity
ASUIS_RS12560	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASUIS_RS12565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASUIS_RS12570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASUIS_RS12575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASUIS_RS12580	COG3177	Filamentation induced by cAMP protein fic
ASUIS_RS12580	COG0666	response to abiotic stimulus
ASUIS_RS12585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASUIS_RS12590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASUIS_RS12605	COG3980	spore coat polysaccharide biosynthesis protein
ASUIS_RS12610	COG2089	acid synthase
ASUIS_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
ASUIS_RS12630	COG0318	PFAM AMP-dependent synthetase and ligase
ASUIS_RS12640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASUIS_RS12645	COG4221	oxidoreductase activity
ASUIS_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
ASUIS_RS12660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASUIS_RS12680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASUIS_RS12690	COG1083	cytidylyl-transferase
ASUIS_RS12695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASUIS_RS12700	COG1086	Polysaccharide biosynthesis protein
ASUIS_RS12710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASUIS_RS12715	COG0148	phosphopyruvate hydratase activity
ASUIS_RS12730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASUIS_RS12745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASUIS_RS12750	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ASUIS_RS12755	COG1007	ATP synthesis coupled electron transport
ASUIS_RS12765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASUIS_RS12770	COG0713	ATP synthesis coupled electron transport
ASUIS_RS12775	COG0839	Belongs to the complex I subunit 6 family
ASUIS_RS12780	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASUIS_RS12785	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ASUIS_RS12790	COG1034	ATP synthesis coupled electron transport
ASUIS_RS12805	COG0649	NAD binding
ASUIS_RS12810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASUIS_RS12815	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASUIS_RS12820	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASUIS_RS12825	COG1222	aaa ATPase
ASUIS_RS12845	COG0659	secondary active sulfate transmembrane transporter activity
ASUIS_RS12860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASUIS_RS12875	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ASUIS_RS12880	COG1252	NADH dehydrogenase
ASUIS_RS12885	COG3287	FIST C domain
ASUIS_RS12885	COG2199	diguanylate cyclase activity
ASUIS_RS12885	COG2200	EAL domain
ASUIS_RS12890	COG0733	neurotransmitter:sodium symporter activity
ASUIS_RS12900	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASUIS_RS12905	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASUIS_RS12910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASUIS_RS12915	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASUIS_RS12920	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASUIS_RS12940	COG0445	tRNA wobble uridine modification
ASUIS_RS12950	COG0348	domain, Protein
ASUIS_RS12955	COG0504	CTP synthase activity
ASUIS_RS12960	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASUIS_RS12960	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ASUIS_RS12990	COG0587	DNA-directed DNA polymerase activity
ASUIS_RS12995	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ASUIS_RS13010	COG0315	cyclic pyranopterin monophosphate synthase activity
ASUIS_RS13015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASUIS_RS13025	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ASUIS_RS13030	COG0159	tryptophan synthase activity
ASUIS_RS13035	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASUIS_RS13040	COG2255	four-way junction helicase activity
ASUIS_RS13045	COG0628	permease
ASUIS_RS13055	COG4628	conserved protein (DUF2132)
ASUIS_RS13090	COG0670	Belongs to the BI1 family
ASUIS_RS13095	COG0352	thiamine-phosphate diphosphorylase activity
ASUIS_RS13105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASUIS_RS13110	COG0233	cytoplasmic translational termination
ASUIS_RS13115	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASUIS_RS13125	COG2814	Major facilitator Superfamily
ASUIS_RS13130	COG3264	Mechanosensitive ion channel
ASUIS_RS13130	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ASUIS_RS13140	COG3022	response to hydroperoxide
ASUIS_RS13145	COG3012	SEC-C Motif Domain Protein
ASUIS_RS13180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASUIS_RS13185	COG1012	belongs to the aldehyde dehydrogenase family
ASUIS_RS13195	COG1704	LemA family
ASUIS_RS13210	COG0546	phosphoglycolate phosphatase activity
ASUIS_RS13230	COG2814	Major facilitator Superfamily
ASUIS_RS13240	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS13245	COG0840	transmembrane signaling receptor activity
ASUIS_RS13250	COG0784	Response regulator, receiver
ASUIS_RS13250	COG3437	response regulator, receiver
ASUIS_RS13275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASUIS_RS13295	COG0679	Auxin Efflux Carrier
ASUIS_RS13305	COG2081	HI0933 family
ASUIS_RS13330	COG1959	2 iron, 2 sulfur cluster binding
ASUIS_RS13345	COG0175	sulfate reduction
ASUIS_RS13350	COG0175	sulfate reduction
ASUIS_RS13355	COG2895	sulfate adenylyltransferase (ATP) activity
ASUIS_RS13360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASUIS_RS13365	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASUIS_RS13375	COG1408	metallophosphoesterase
ASUIS_RS13385	COG2307	Protein conserved in bacteria
ASUIS_RS13385	COG2308	Evidence 4 Homologs of previously reported genes of
ASUIS_RS13395	COG0840	transmembrane signaling receptor activity
ASUIS_RS13415	COG2308	Evidence 4 Homologs of previously reported genes of
ASUIS_RS13420	COG1217	gtp-binding protein TYPA
ASUIS_RS13435	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASUIS_RS13465	COG0745	RESPONSE REGULATOR receiver
ASUIS_RS13470	COG2205	protein histidine kinase activity
ASUIS_RS13475	COG2391	methyltransferase activity
ASUIS_RS13480	COG0425	Belongs to the sulfur carrier protein TusA family
ASUIS_RS13485	COG0784	Response regulator, receiver
ASUIS_RS13485	COG3437	response regulator, receiver
ASUIS_RS13490	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ASUIS_RS13495	COG2066	Belongs to the glutaminase family
ASUIS_RS13500	COG2860	membrane
ASUIS_RS13510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASUIS_RS13515	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group