locus-tag class description AVENP_RS00005 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) AVENP_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AVENP_RS00015 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AVENP_RS00020 ENOG4105CAY ferredoxin--nadp reductase AVENP_RS00025 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) AVENP_RS00035 ENOG4108JHT EamA-like transporter family AVENP_RS00040 ENOG4105W39 Membrane AVENP_RS00050 ENOG4108M5V ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) AVENP_RS00065 ENOG4105BZU Histidine kinase AVENP_RS00075 ENOG4108JUA Transcriptional regulator AVENP_RS00085 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) AVENP_RS00090 ENOG4105CPC Aldo Keto reductase AVENP_RS00095 ENOG4105F4R Transcriptional regulator mode AVENP_RS00100 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AVENP_RS00105 ENOG4105ECW sulfate abc transporter AVENP_RS00120 ENOG4108BSC Methyltransferase AVENP_RS00125 ENOG4105E0A ABC, transporter AVENP_RS00130 ENOG4105EHG Permease protein AVENP_RS00150 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AVENP_RS00155 ENOG4105E0C molybdate abc transporter AVENP_RS00165 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AVENP_RS00170 ENOG4105F4R Transcriptional regulator mode AVENP_RS00180 ENOG4105D0B Nitrogenase protein alpha chain AVENP_RS00190 ENOG4105DSM The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity) AVENP_RS00195 ENOG4105CSR polyphosphate kinase 2 AVENP_RS00210 ENOG4107SDU Methyl-accepting chemotaxis AVENP_RS00215 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AVENP_RS00220 ENOG4105KXW Ferredoxin AVENP_RS00230 ENOG4105XV5 nifz family AVENP_RS00240 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) AVENP_RS00245 ENOG4108VQE nitrogen fixation protein AVENP_RS00250 ENOG4108UR2 Nitrogen fixation protein NifX AVENP_RS00280 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS00285 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AVENP_RS00310 ENOG4105CNW domain protein AVENP_RS00320 ENOG4105CGC Nitrogenase cofactor biosynthesis protein NifB AVENP_RS00335 ENOG4107S73 homocitrate synthase AVENP_RS00365 ENOG4105EI2 Pseudouridine synthase AVENP_RS00370 ENOG4107QTF adenylosuccinate lyase AVENP_RS00375 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AVENP_RS00380 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AVENP_RS00405 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase AVENP_RS00425 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) AVENP_RS00435 ENOG4105BZ8 glutamate synthase AVENP_RS00440 ENOG4105UYK outer membrane protein a AVENP_RS00460 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase AVENP_RS00465 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) AVENP_RS00480 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AVENP_RS00490 ENOG4105CH5 extracellular solute-binding protein, family 7 AVENP_RS00500 ENOG4105BZU Histidine kinase AVENP_RS00505 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) AVENP_RS00510 ENOG4107QR9 Iron-sulfur cluster binding protein AVENP_RS00515 ENOG4107R5T Cysteine-rich domain AVENP_RS00525 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AVENP_RS00530 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein AVENP_RS00535 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AVENP_RS00540 ENOG4105C1J atp-dependent rna helicase AVENP_RS00545 ENOG4105CJ3 phosphate transporter AVENP_RS00555 ENOG4105CAQ asparagine synthetase AVENP_RS00565 ENOG4105E7Q Cob(II)yrinic acid a,c-diamide reductase AVENP_RS00570 ENOG4105CH5 extracellular solute-binding protein, family 7 AVENP_RS00575 ENOG4105E33 succinate dehydrogenase AVENP_RS00580 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) AVENP_RS00590 ENOG4108IAB Phoh family AVENP_RS00595 ENOG4108YXA Membrane AVENP_RS00600 ENOG4105D1H recombination factor protein RarA AVENP_RS00605 ENOG4105FE9 pseudouridine synthase AVENP_RS00610 ENOG4105C2X Arabinose 5-phosphate isomerase AVENP_RS00620 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) AVENP_RS00625 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) AVENP_RS00640 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs AVENP_RS00645 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) AVENP_RS00685 ENOG4108YYC ycei family AVENP_RS00695 ENOG4107QJQ Mate efflux family protein AVENP_RS00700 ENOG4105D6E homoserine dehydrogenase AVENP_RS00705 ENOG4105CHM Aminotransferase AVENP_RS00725 ENOG41082DI 50s ribosomal protein l31 AVENP_RS00730 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) AVENP_RS00790 ENOG4107QHF type ii secretion system protein e AVENP_RS00820 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR AVENP_RS00825 ENOG4108UR8 BAX protein AVENP_RS00830 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) AVENP_RS00835 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) AVENP_RS00840 ENOG41084QV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) AVENP_RS00845 ENOG4105CXB phosphoribosylaminoimidazole synthetase AVENP_RS00850 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AVENP_RS00860 ENOG4108YYC ycei family AVENP_RS00865 ENOG4105GVJ transcriptional regulator AVENP_RS00870 ENOG4105C2I pirin domain protein AVENP_RS00880 ENOG4108YYC ycei family AVENP_RS00885 ENOG4107RIH serine-glyoxylate aminotransferase AVENP_RS00890 ENOG4105CYE ATP phosphoribosyltransferase regulatory subunit AVENP_RS00895 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis AVENP_RS00905 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain AVENP_RS00910 ENOG4108ZAI phosphatidylglycerophosphatase a AVENP_RS00920 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) AVENP_RS00935 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) AVENP_RS00940 ENOG4105D1F ATP-binding protein AVENP_RS00945 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase AVENP_RS00965 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) AVENP_RS00970 ENOG4105EQQ protein containing aminopeptidase domain AVENP_RS00995 ENOG4107Y9U Membrane AVENP_RS01005 ENOG4108R5S membrane AVENP_RS01010 ENOG4108I6A alcohol dehydrogenase AVENP_RS01035 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) AVENP_RS01045 ENOG4108W2Y isochorismatase AVENP_RS01060 ENOG4107QWP ABC-2 type transporter AVENP_RS01065 ENOG4107QWP ABC-2 type transporter AVENP_RS01070 ENOG4105CJ1 ABC, transporter AVENP_RS01080 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AVENP_RS01085 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS01105 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AVENP_RS01120 ENOG4108KK1 membrane protein AbrB duplication AVENP_RS01125 ENOG4107B2H carbonic anhydrase AVENP_RS01155 ENOG4105DDK oxidoreductase, beta subunit AVENP_RS01170 ENOG4105EJ5 oxidoreductase gamma subunit AVENP_RS01175 ENOG4107XGZ Hydrolase AVENP_RS01185 ENOG4108UJD 30S ribosomal protein S9 AVENP_RS01190 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) AVENP_RS01200 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS01210 ENOG4108UTW Plays a role in the regulation of phosphate uptake AVENP_RS01215 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) AVENP_RS01220 ENOG4105E2Z phosphate ABC transporter (Permease AVENP_RS01225 ENOG4105C8U phosphate abc transporter AVENP_RS01230 ENOG4108M8H domain protein AVENP_RS01235 ENOG4105PWN phosphate abc transporter AVENP_RS01245 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) AVENP_RS01250 ENOG4108317 Binds directly to 16S ribosomal RNA (By similarity) AVENP_RS01255 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) AVENP_RS01260 ENOG410813J This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) AVENP_RS01265 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AVENP_RS01275 ENOG4107SA8 fad-dependent pyridine nucleotide-disulfide oxidoreductase AVENP_RS01285 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) AVENP_RS01290 ENOG41084M8 50s ribosomal protein L35 AVENP_RS01295 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) AVENP_RS01330 ENOG4105KNE Phosphatidate cytidylyltransferase AVENP_RS01335 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) AVENP_RS01355 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AVENP_RS01360 ENOG4108ZJT translation initiation factor, Sui1 AVENP_RS01365 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) AVENP_RS01370 ENOG4105VF7 tolerance protein AVENP_RS01375 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) AVENP_RS01435 ENOG4105C4M (Ubiquinol oxidase) subunit I AVENP_RS01445 ENOG4105D9Q decarboxylase (Beta subunit) AVENP_RS01450 ENOG4105PV1 biotin lipoyl attachment domaiN-containing protein AVENP_RS01470 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) AVENP_RS01505 ENOG4108JJA ABC, transporter AVENP_RS01520 ENOG4105BZU Histidine kinase AVENP_RS01525 ENOG4105CV1 Transketolase (EC 2.2.1.1) AVENP_RS01535 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AVENP_RS01560 ENOG41067MG lrgb family AVENP_RS01565 ENOG41085FC arsR family transcriptional regulator AVENP_RS01585 ENOG4108UXE Protein tyrosine phosphatase AVENP_RS01595 ENOG4105KK4 UPF0060 membrane protein AVENP_RS01615 ENOG4105CK2 sodium dicarboxylate symporter AVENP_RS01620 ENOG4105CHH sulfate transporter AVENP_RS01630 ENOG4105CEY Amp-dependent synthetase and ligase AVENP_RS01635 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) AVENP_RS01665 ENOG4108YZA Nitrogen regulatory protein pii AVENP_RS01675 ENOG4108YZA Nitrogen regulatory protein pii AVENP_RS01680 ENOG4105EKE dihydroorotase AVENP_RS01685 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AVENP_RS01690 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) AVENP_RS01700 ENOG4105VS8 Flagellar biosynthetic protein fliq AVENP_RS01725 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) AVENP_RS01735 ENOG4107TPX flagellar hook-associated AVENP_RS01755 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) AVENP_RS01760 ENOG4107R03 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) AVENP_RS01775 ENOG410829W Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) AVENP_RS01780 ENOG4105GSH Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) AVENP_RS01790 ENOG4105EAC phosphoserine phosphatase AVENP_RS01795 ENOG4107V25 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AVENP_RS01800 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase AVENP_RS01805 ENOG4105DRB nucleoside-specific channel-forming protein AVENP_RS01810 ENOG4105KUZ arsenate reductase AVENP_RS01815 ENOG410855J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) AVENP_RS01820 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) AVENP_RS01830 ENOG4105CHM Aminotransferase AVENP_RS01840 ENOG4105DFU Cell wall formation (By similarity) AVENP_RS01850 ENOG4105PXI polysaccharide deacetylase AVENP_RS01855 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase AVENP_RS01860 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) AVENP_RS01870 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) AVENP_RS01875 ENOG4108UUM single-stranded DNA-binding protein AVENP_RS01880 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) AVENP_RS01885 ENOG4105C8N cysteinyl-tRNA synthetase AVENP_RS01890 ENOG4105CHV Transcription elongation factor NusA AVENP_RS01900 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AVENP_RS01905 ENOG4105KB8 (LipO)protein AVENP_RS01915 ENOG4105DVY radical SAM domain protein AVENP_RS01930 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AVENP_RS01935 ENOG41082UM UPF0102 protein AVENP_RS01950 ENOG4105UYK outer membrane protein a AVENP_RS01970 ENOG4105C8Y Acetylornithine aminotransferase AVENP_RS01980 ENOG4105CXT aspartate transcarbamylase AVENP_RS02005 ENOG4108UMN azlc family AVENP_RS02010 ENOG4105KMT branched-chain amino acid AVENP_RS02015 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AVENP_RS02020 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) AVENP_RS02025 ENOG4105YQ2 50s ribosomal protein l32 AVENP_RS02035 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) AVENP_RS02045 ENOG4105D3R alkyl hydroperoxide reductase AVENP_RS02050 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) AVENP_RS02055 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AVENP_RS02060 ENOG4108UMI ABC transporter, permease AVENP_RS02065 ENOG4105D01 (LipO)protein AVENP_RS02070 ENOG4105D82 Glutamate dehydrogenase AVENP_RS02075 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) AVENP_RS02080 ENOG4107QMP dna polymerase iii subunits gamma and tau AVENP_RS02090 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) AVENP_RS02105 ENOG4105C7F AcnD-accessory protein PrpF AVENP_RS02110 ENOG4108I0Z Aconitate hydratase AVENP_RS02115 ENOG4105BZN citrate synthase AVENP_RS02120 ENOG4105CR4 methylisocitrate lyase AVENP_RS02155 ENOG4105C5I Dehydrogenase AVENP_RS02165 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) AVENP_RS02170 ENOG4105C09 Bile acid AVENP_RS02180 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AVENP_RS02185 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AVENP_RS02190 ENOG4107QSI ABC, transporter AVENP_RS02205 ENOG4105C9U ATP-dependent DNA helicase RecQ AVENP_RS02215 ENOG41082BM Transcriptional regulator, arsr family AVENP_RS02220 ENOG4105C59 p-type ATPase AVENP_RS02235 ENOG4108VKG metal-dependent hydrolase AVENP_RS02240 ENOG4106K80 AVENP_RS02245 ENOG4106K80 AVENP_RS02270 ENOG4105E33 succinate dehydrogenase AVENP_RS02275 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) AVENP_RS02280 ENOG4108S24 Fumarate reduCtase AVENP_RS02285 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AVENP_RS02290 ENOG4105C8S subunit m AVENP_RS02295 ENOG4105D65 subunit l AVENP_RS02300 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AVENP_RS02305 ENOG4107YX3 NADH dehydrogenase subunit j AVENP_RS02315 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) AVENP_RS02325 ENOG4105BZN citrate synthase AVENP_RS02340 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AVENP_RS02345 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AVENP_RS02350 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain AVENP_RS02355 ENOG4105C87 Aminotransferase class I and II AVENP_RS02360 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) AVENP_RS02365 ENOG4107XM3 UPF0442 protein AVENP_RS02370 ENOG4107XM3 UPF0442 protein AVENP_RS02380 ENOG4108VHG Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) AVENP_RS02385 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) AVENP_RS02405 ENOG4108UI1 Probably functions as a manganese efflux pump (By similarity) AVENP_RS02420 ENOG4105BZ1 (ABC) transporter AVENP_RS02430 ENOG4107ZSV Receptor AVENP_RS02445 ENOG4105PGM cation diffusion facilitator family transporter AVENP_RS02455 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) AVENP_RS02470 ENOG410829K Lysine exporter protein (Lyse ygga) AVENP_RS02475 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS02480 ENOG4105EJQ L-serine dehydratase AVENP_RS02490 ENOG4105CDA abc transporter atp-binding protein AVENP_RS02495 ENOG4105DRP amino acid AbC transporter AVENP_RS02500 ENOG4105EZ7 amino acid ABC transporter AVENP_RS02505 ENOG4107QXX ABC transporter AVENP_RS02510 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AVENP_RS02530 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) AVENP_RS02535 ENOG4105GXZ Ferredoxin-type protein NapH AVENP_RS02540 ENOG4108BGM Quinol dehydrogenase periplasmic component AVENP_RS02545 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AVENP_RS02550 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AVENP_RS02565 ENOG4107QYG anthranilate phosphoribosyltransferase AVENP_RS02570 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AVENP_RS02575 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) AVENP_RS02585 ENOG4108KA0 Inherit from COG: Phosphoesterase, DHHA1 AVENP_RS02590 ENOG4105K4P CoA-binding domain protein AVENP_RS02595 ENOG4105DHQ Histidine kinase AVENP_RS02600 ENOG4105ETX regulatoR AVENP_RS02605 ENOG4105EIN peptidylprolyl cis-trans isomerase AVENP_RS02610 ENOG4105D2N Aldolase AVENP_RS02615 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) AVENP_RS02635 ENOG4105DEN Luciferase family AVENP_RS02655 ENOG4105DZG Dehydrogenase AVENP_RS02680 ENOG4105WF7 pyrroloquinoline quinone biosynthesis protein d AVENP_RS02685 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E AVENP_RS02690 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AVENP_RS02700 ENOG4105D38 putrescine abc transporter AVENP_RS02705 ENOG4107RUE extracellular solute-binding protein family 1 AVENP_RS02715 ENOG4105BZU Histidine kinase AVENP_RS02730 ENOG4105VEQ Cold shock protein AVENP_RS02735 ENOG4109015 Biopolymer transport protein exbD tolR AVENP_RS02740 ENOG4105M8K biopolymer transport protein AVENP_RS02750 ENOG4105BZU Histidine kinase AVENP_RS02755 ENOG4105BZU Histidine kinase AVENP_RS02765 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) AVENP_RS02780 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) AVENP_RS02785 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) AVENP_RS02795 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate AVENP_RS02810 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) AVENP_RS02815 ENOG4105VIE preprotein translocase, subunit YajC AVENP_RS02820 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AVENP_RS02825 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AVENP_RS02845 ENOG4105C8T Leucyl-tRNA synthetase AVENP_RS02855 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AVENP_RS02870 ENOG4106GFD transport protein AVENP_RS02875 ENOG4105M8K biopolymer transport protein AVENP_RS02895 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) AVENP_RS02900 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) AVENP_RS02945 ENOG41090R7 Ferric uptake AVENP_RS02985 ENOG4105C9Q fumarate hydratase class II AVENP_RS02995 ENOG4105BZU Histidine kinase AVENP_RS03000 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AVENP_RS03010 ENOG4105KVH Transcriptional regulator AVENP_RS03015 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS03040 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) AVENP_RS03070 ENOG4108IU3 tonb-dependent siderophore receptor AVENP_RS03075 ENOG4107E2E PKHD-type hydroxylase AVENP_RS03115 ENOG4105EKE dihydroorotase AVENP_RS03120 ENOG4108N6H 6-pyruvoyl tetrahydrobiopterin synthase AVENP_RS03165 ENOG4105CGH 5'-nucleotidase AVENP_RS03180 ENOG4105D7X high-affinity nickel-transporter AVENP_RS03225 ENOG4108JA2 transcriptioN-repair coupling factor AVENP_RS03230 ENOG4106492 Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO (By similarity) AVENP_RS03265 ENOG4105CBX hi0933 family AVENP_RS03270 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS03290 ENOG4105D48 metallophosphoesterase AVENP_RS03310 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AVENP_RS03315 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) AVENP_RS03320 ENOG4108V3W Chemotaxis protein, CheW AVENP_RS03340 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) AVENP_RS03345 ENOG41084FT Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) AVENP_RS03355 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) AVENP_RS03360 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) AVENP_RS03370 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS03375 ENOG4107RN3 metallophosphoesterase AVENP_RS03385 ENOG4108YYC ycei family AVENP_RS03400 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) AVENP_RS03410 ENOG4105ECY inositol monophosphatase AVENP_RS03415 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) AVENP_RS03430 ENOG4105FR1 rard protein AVENP_RS03435 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP AVENP_RS03440 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) AVENP_RS03450 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) AVENP_RS03460 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AVENP_RS03465 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) AVENP_RS03470 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AVENP_RS03490 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) AVENP_RS03495 ENOG4107SVH Potassium channel protein AVENP_RS03520 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) AVENP_RS03545 ENOG4105I7I quinohemoprotein amine dehydrogenase gamma subunit AVENP_RS03570 ENOG4105J9X quinohemoprotein amine dehydrogenase gamma subunit AVENP_RS03580 ENOG4105BZ1 (ABC) transporter AVENP_RS03595 ENOG4105BZU Histidine kinase AVENP_RS03600 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase AVENP_RS03605 ENOG4105ECP epimerase AVENP_RS03610 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) AVENP_RS03620 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS03645 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) AVENP_RS03650 ENOG4105UYK outer membrane protein a AVENP_RS03655 ENOG4105CDV Ompa motb domain protein AVENP_RS03660 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AVENP_RS03670 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) AVENP_RS03680 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) AVENP_RS03685 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase AVENP_RS03690 ENOG4105DC7 peptidase M24 AVENP_RS03695 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) AVENP_RS03700 ENOG4107SYB Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) AVENP_RS03715 ENOG4108IJ2 phosphate acetyltransferase AVENP_RS03720 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AVENP_RS03725 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AVENP_RS03730 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) AVENP_RS03740 ENOG4107QN1 sodium solute AVENP_RS03750 ENOG4107QN1 sodium solute AVENP_RS03760 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) AVENP_RS03770 ENOG4107QN1 sodium solute AVENP_RS03780 ENOG4108STX response regulator AVENP_RS03785 ENOG4105BZU Histidine kinase AVENP_RS03830 ENOG4105CEV competence damage-inducible protein AVENP_RS03835 ENOG4107RSR Malate quinone oxidoreductase AVENP_RS03840 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AVENP_RS03855 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AVENP_RS03865 ENOG4105CE9 30S ribosomal protein S2 AVENP_RS03870 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) AVENP_RS03885 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) AVENP_RS03890 ENOG4105BZU Histidine kinase AVENP_RS03895 ENOG4105C59 p-type ATPase AVENP_RS03910 ENOG4107H6U ABC transporter AVENP_RS03915 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) AVENP_RS03930 ENOG41074MP UPF0103 Mediator of ErbB2-driven cell motility-containing protein AVENP_RS03935 ENOG4107S90 membrAne AVENP_RS03940 ENOG4105FDK ABC transporter AVENP_RS03955 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) AVENP_RS03960 ENOG4105EUU Sel1 domain protein repeat-containing protein AVENP_RS03970 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) AVENP_RS03980 ENOG4105DHT Metal Dependent Phosphohydrolase AVENP_RS03985 ENOG4108HM4 ABC transporter AVENP_RS03990 ENOG4105BZU Histidine kinase AVENP_RS03995 ENOG4108YZA Nitrogen regulatory protein pii AVENP_RS04000 ENOG4105ENA helicase AVENP_RS04010 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) AVENP_RS04035 ENOG41088H4 Diheme cytochrome SoxA (Sulfur oxidation) AVENP_RS04070 ENOG4107R7Y intracellular protease Pfpi family AVENP_RS04085 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AVENP_RS04100 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AVENP_RS04115 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase AVENP_RS04150 ENOG4105BZS acriflavin resistance protein AVENP_RS04165 ENOG4107RDB Major Facilitator AVENP_RS04170 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) AVENP_RS04200 ENOG410901F (LipO)protein AVENP_RS04205 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) AVENP_RS04245 ENOG4105CNG UPF0061 protein AVENP_RS04295 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AVENP_RS04305 ENOG4107R3N Filamentation induced by cAMP protein fic AVENP_RS04320 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) AVENP_RS04325 ENOG4105C9B Cysteine desulfurase AVENP_RS04335 ENOG4105C3K feS assembly ATPase SufC AVENP_RS04350 ENOG4107RIU May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity) AVENP_RS04355 ENOG4105E82 cytochrome subunit of dehydrogenase AVENP_RS04365 ENOG4105CJW magnesium transporter AVENP_RS04370 ENOG4105CH7 arginosuccinase AVENP_RS04380 ENOG4105CUZ uba thif-type nad fad binding protein AVENP_RS04385 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) AVENP_RS04390 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase AVENP_RS04425 ENOG4105CSM endonuclease III AVENP_RS04460 ENOG4108YZG isomerase AVENP_RS04465 ENOG4105C3F Signal peptidase i AVENP_RS04470 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) AVENP_RS04475 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) AVENP_RS04480 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) AVENP_RS04495 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AVENP_RS04505 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AVENP_RS04510 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AVENP_RS04515 ENOG410692R Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) AVENP_RS04520 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) AVENP_RS04530 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) AVENP_RS04535 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) AVENP_RS04540 ENOG4105CRQ synthase (Component I) AVENP_RS04550 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) AVENP_RS04555 ENOG4105CRK lysyL-tRNA synthetase AVENP_RS04570 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) AVENP_RS04575 ENOG4105CDU Replicative dna helicase AVENP_RS04585 ENOG4105CMR udp-glucose 4-epimerase AVENP_RS04595 ENOG4107QQG Dehydrogenase AVENP_RS04600 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) AVENP_RS04605 ENOG4105C1B dTDP-glucose 4-6-dehydratase AVENP_RS04610 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AVENP_RS04635 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) AVENP_RS04650 ENOG4107QJZ Glycosyl transferase, family 2 AVENP_RS04670 ENOG41068W6 Capsular polysaccharide biosynthesis protein AVENP_RS04700 ENOG4105CPQ Dehydrogenase AVENP_RS04705 ENOG4108PTS heparinase ii AVENP_RS04720 ENOG4105ESV Glycosyl transferase, family 4 AVENP_RS04725 ENOG4105C5E polysaccharide biosynthesis protein AVENP_RS04740 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) AVENP_RS04745 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) AVENP_RS04755 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) AVENP_RS04765 ENOG4107QW4 alcohol dehydrogenase AVENP_RS04770 ENOG4107SET aldo keto reductase AVENP_RS04780 ENOG41088CC tellurite resistance protein tehB AVENP_RS04785 ENOG4105CF7 AraC family transcriptional regulator AVENP_RS04795 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AVENP_RS04800 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AVENP_RS04805 ENOG4108VHC Short-chain dehydrogenase reductase Sdr AVENP_RS04815 ENOG4105BZS acriflavin resistance protein AVENP_RS04855 ENOG4105C3G gtp-binding protein AVENP_RS04875 ENOG4105NBK UPF0345 protein AVENP_RS04885 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i AVENP_RS04905 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) AVENP_RS04910 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AVENP_RS04915 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS04920 ENOG4105CIH Imidazole acetol-phosphate transaminase AVENP_RS04950 ENOG4105DUM transcriptional regulator, lysR family AVENP_RS04955 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AVENP_RS04960 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AVENP_RS04970 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AVENP_RS05140 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) AVENP_RS05145 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) AVENP_RS05155 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS05160 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) AVENP_RS05165 ENOG4105CPF Cell wall formation (By similarity) AVENP_RS05175 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) AVENP_RS05190 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS05195 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS05200 ENOG4107QMZ Dehydrogenase AVENP_RS05205 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) AVENP_RS05210 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) AVENP_RS05215 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) AVENP_RS05220 ENOG4105KZZ One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) AVENP_RS05225 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity AVENP_RS05230 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) AVENP_RS05235 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) AVENP_RS05240 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) AVENP_RS05245 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) AVENP_RS05250 ENOG41084HJ 50s ribosomal protein l29 AVENP_RS05255 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal AVENP_RS05260 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) AVENP_RS05265 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) AVENP_RS05270 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits AVENP_RS05275 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) AVENP_RS05280 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) AVENP_RS05285 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) AVENP_RS05290 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) AVENP_RS05295 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) AVENP_RS05300 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) AVENP_RS05305 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AVENP_RS05310 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AVENP_RS05315 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) AVENP_RS05325 ENOG4108UN4 phage SPO1 DNA polymerase-related protein AVENP_RS05335 ENOG4105C9M aspartyl-trna synthetase AVENP_RS05350 ENOG4105CCT upf0313 protein AVENP_RS05355 ENOG4105N14 lysine exporter protein LysE YggA AVENP_RS05360 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) AVENP_RS05365 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) AVENP_RS05380 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AVENP_RS05385 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) AVENP_RS05400 ENOG4106Z1T Nicotinamide Mononucleotide Transporter AVENP_RS05405 ENOG4108V06 Glutathione peroxidase AVENP_RS05410 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS05415 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS05435 ENOG4108SEK ompa motb domain protein AVENP_RS05440 ENOG4105E14 MotA TolQ exbB proton channel AVENP_RS05450 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS05460 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) AVENP_RS05465 ENOG4105C8U phosphate abc transporter AVENP_RS05470 ENOG4105E2Z phosphate ABC transporter (Permease AVENP_RS05475 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) AVENP_RS05505 ENOG4105CNM Receptor AVENP_RS05525 ENOG4105C32 Amino acid ABC transporter (Permease) AVENP_RS05535 ENOG4105D5T phosphonate abc transporter AVENP_RS05540 ENOG4108IV0 ABC, transporter AVENP_RS05565 ENOG4105C7N Xanthine uracil vitamin C permease AVENP_RS05575 ENOG4105E5Q amino acid AbC transporter AVENP_RS05580 ENOG4105E5Q amino acid AbC transporter AVENP_RS05600 ENOG4105DHG Allantoate amidinohydrolase AVENP_RS05605 ENOG4108Z2U ureidoglycolate hydrolase AVENP_RS05610 ENOG4108YZ9 Urea amidohydrolase subunit gamma AVENP_RS05615 ENOG4105CQM Urea amidohydrolase subunit alpha AVENP_RS05630 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) AVENP_RS05635 ENOG4108VYJ response regulator receiver protein AVENP_RS05660 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS05670 ENOG4107Z3H Transcriptional regulator, TetR family AVENP_RS05700 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AVENP_RS05705 ENOG4108MRH transcriptional regulatory protein AVENP_RS05735 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AVENP_RS05740 ENOG4105QAX Iron-sulfur AVENP_RS05750 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) AVENP_RS05785 ENOG4105NVB glycoside hydrolase, family 19 AVENP_RS05800 ENOG4105KME endoribonuclease L-psp AVENP_RS05805 ENOG4107QMZ Dehydrogenase AVENP_RS05810 ENOG4105BZG amino acid carrier protein AVENP_RS05815 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AVENP_RS05820 ENOG4105DF3 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity) AVENP_RS05825 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) AVENP_RS05835 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS05865 ENOG4107SDU Methyl-accepting chemotaxis AVENP_RS05870 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase AVENP_RS05885 ENOG4105DDY UPF0142 protein ycaO AVENP_RS05905 ENOG4105C1J atp-dependent rna helicase AVENP_RS05930 ENOG4108RPX mosc domain containing protein AVENP_RS05935 ENOG4105C8Y Acetylornithine aminotransferase AVENP_RS05940 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AVENP_RS05945 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AVENP_RS05950 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) AVENP_RS05960 ENOG4105CKD glutathione-regulated potassium-efflux system protein AVENP_RS05980 ENOG4108ISG Major Facilitator AVENP_RS05985 ENOG4105C94 Transporter AVENP_RS05995 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) AVENP_RS06035 ENOG4105MN5 HAD-superfamily hydrolase subfamily IA variant 3 AVENP_RS06040 ENOG4108URH decarboxylase AVENP_RS06060 ENOG4105CDY transcriptional regulatory protein AVENP_RS06080 ENOG4107QPN acyl-Coa dehydrogenase AVENP_RS06085 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AVENP_RS06090 ENOG4105CHU acetyl-coa acetyltransferase AVENP_RS06095 ENOG4108IQE Amp-dependent synthetase and ligase AVENP_RS06110 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AVENP_RS06120 ENOG4107QIJ Aconitate hydratase 2 AVENP_RS06125 ENOG4108JYZ YitT family AVENP_RS06135 ENOG4108594 Permease of the drug metabolite transporter AVENP_RS06140 ENOG4108JQ1 Dehydrogenase AVENP_RS06155 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein AVENP_RS06165 ENOG4108VP3 Lysine exporter protein (LysE YggA) AVENP_RS06170 ENOG4105E0X reductase AVENP_RS06180 ENOG4105BZU Histidine kinase AVENP_RS06195 ENOG4105FDK ABC transporter AVENP_RS06225 ENOG4105BZU Histidine kinase AVENP_RS06245 ENOG4105E3S small subunit AVENP_RS06250 ENOG4105DPX Hydrogenase, large subunit AVENP_RS06295 ENOG4105E0K tonB-dependent siderophore receptor AVENP_RS06300 ENOG4108R6W Transcriptional regulator, ARAC family AVENP_RS06305 ENOG4108USZ hydrogenase AVENP_RS06310 ENOG4108P97 AVENP_RS06390 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) AVENP_RS06410 ENOG4105D3Y Na H antiporter AVENP_RS06425 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) AVENP_RS06435 ENOG4107TIF Phenazine biosynthesis protein, PhzF family AVENP_RS06445 ENOG4105VCH membrane AVENP_RS06460 ENOG4105CKW Inner membrane protein yedI AVENP_RS06470 ENOG4105CBX hi0933 family AVENP_RS06475 ENOG4105BZU Histidine kinase AVENP_RS06480 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS06490 ENOG4107XQ1 cobalamin (vitamin B12) biosynthesis CbiM protein AVENP_RS06520 ENOG4105CVR type I restriction-modification system AVENP_RS06530 ENOG4105DFS Conserved Protein AVENP_RS06550 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) AVENP_RS06555 ENOG4105WRB Hydrogenase assembly chaperone hypC hupF AVENP_RS06560 ENOG4105CQS hydrogenase expression formation protein HypD AVENP_RS06565 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AVENP_RS06575 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 AVENP_RS06585 ENOG4105C45 hydrogenase expression formation protein (HypE) AVENP_RS06600 ENOG4105C32 Amino acid ABC transporter (Permease) AVENP_RS06605 ENOG4105CF8 branched-chain amino acid ABC transporter, permease AVENP_RS06610 ENOG4105C0Z ABC transporter AVENP_RS06615 ENOG4108IV0 ABC, transporter AVENP_RS06620 ENOG4105BZU Histidine kinase AVENP_RS06645 ENOG4105C25 Primosomal protein n' AVENP_RS06650 ENOG4105EJ3 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity) AVENP_RS06655 ENOG4105C5H ABC transporter AVENP_RS06665 ENOG4108UPT UPF0178 protein AVENP_RS06680 ENOG4105CAK Cell division ATP-binding protein ftsE AVENP_RS06685 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) AVENP_RS06695 ENOG4105C34 Pseudouridine synthase AVENP_RS06700 ENOG4105CNI cell division protein FtsW AVENP_RS06715 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase AVENP_RS06720 ENOG4105NBK UPF0345 protein AVENP_RS06740 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AVENP_RS06745 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AVENP_RS06750 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AVENP_RS06765 ENOG41067V7 50S ribosomal protein L36 AVENP_RS06770 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits AVENP_RS06775 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) AVENP_RS06780 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) AVENP_RS06785 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AVENP_RS06790 ENOG4108ZT0 50S ribosomal protein l17 AVENP_RS06795 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) AVENP_RS06800 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AVENP_RS06810 ENOG41082IR Excinuclease ABC C subunit domain protein AVENP_RS06820 ENOG4108YZY peptidylprolyl cis-trans isomerase AVENP_RS06825 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) AVENP_RS06830 ENOG4108J5H Homocysteine s-methyltransferase AVENP_RS06835 ENOG4105N14 lysine exporter protein LysE YggA AVENP_RS06890 ENOG4105DAA L-lactate AVENP_RS06900 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) AVENP_RS06915 ENOG4105D17 glycoside hydrolase, family 3 domain protein AVENP_RS06920 ENOG4105DSF transport protein AVENP_RS06925 ENOG4105BZ1 (ABC) transporter AVENP_RS06965 ENOG4105I03 Flagellin AVENP_RS06985 ENOG4105CVP deoxyribo-dipyrimidine photolyase AVENP_RS06995 ENOG4105E4P ATPase (AAA AVENP_RS07010 ENOG4105DY9 regulatoR AVENP_RS07020 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) AVENP_RS07025 ENOG4105C1J atp-dependent rna helicase AVENP_RS07030 ENOG4105D49 3-dehydroquinate synthase AVENP_RS07040 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AVENP_RS07045 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AVENP_RS07055 ENOG4108RIR Molybdenum cofactor biosynthesis protein AVENP_RS07060 ENOG4105C8P )-transporter AVENP_RS07070 ENOG4105BZU Histidine kinase AVENP_RS07080 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AVENP_RS07095 ENOG4105QNF Outer membrane lipoprotein AVENP_RS07105 ENOG4105EMU Dehydrogenase AVENP_RS07115 ENOG4105C5H ABC transporter AVENP_RS07120 ENOG4108S4H thioesterase Superfamily protein AVENP_RS07125 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) AVENP_RS07130 ENOG4105I08 Pseudouridine synthase AVENP_RS07140 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) AVENP_RS07160 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) AVENP_RS07170 ENOG4108JJB ABC transporter AVENP_RS07175 ENOG4105EHG Permease protein AVENP_RS07180 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) AVENP_RS07185 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) AVENP_RS07205 ENOG4105C98 muts2 protein AVENP_RS07225 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) AVENP_RS07260 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) AVENP_RS07265 ENOG4105KNI merR family transcriptional Regulator AVENP_RS07270 ENOG4105DVC DnaJ domain protein AVENP_RS07285 ENOG4107Z9R response regulator AVENP_RS07305 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AVENP_RS07315 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) AVENP_RS07330 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AVENP_RS07335 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) AVENP_RS07345 ENOG410841J DNA-binding protein Hu AVENP_RS07355 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) AVENP_RS07395 ENOG4105DJI Methylaspartate mutase, E subunit AVENP_RS07405 ENOG4105E9K Isocitrate dehydrogenase AVENP_RS07420 ENOG4105D60 lipoprotein releasing system transmembrane protein AVENP_RS07425 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving AVENP_RS07440 ENOG4105VTR Integrase AVENP_RS07540 ENOG4105CIN aminoacyl-histidine dipeptidase AVENP_RS07555 ENOG4105CRE cytochrome C AVENP_RS07560 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) AVENP_RS07575 ENOG4105C5X domain protein AVENP_RS07595 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) AVENP_RS07605 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) AVENP_RS07610 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) AVENP_RS07620 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AVENP_RS07635 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS07640 ENOG4105BZU Histidine kinase AVENP_RS07645 ENOG4105C08 Histidine kinase AVENP_RS07650 ENOG4105EEX Two component transcriptional regulator (Winged helix family AVENP_RS07655 ENOG4105CZN Potassium uptake protein AVENP_RS07660 ENOG4107ZYR domain protein AVENP_RS07685 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) AVENP_RS07690 ENOG4105CDH Citrulline--aspartate ligase AVENP_RS07715 ENOG4108I0Q anthranilate phosphoribosyltransferase AVENP_RS07720 ENOG4105K8N protein family UPF0079, ATPase AVENP_RS07725 ENOG4108IUZ ABC transporter AVENP_RS07730 ENOG4105BZU Histidine kinase AVENP_RS07735 ENOG4105BZU Histidine kinase AVENP_RS07740 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) AVENP_RS07745 ENOG4105C2M dna polymerase I AVENP_RS07765 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) AVENP_RS07780 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) AVENP_RS07810 ENOG4105C8J )-transporter AVENP_RS07825 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) AVENP_RS07830 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) AVENP_RS07835 ENOG41084AD Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) AVENP_RS07840 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) AVENP_RS07860 ENOG4105C4K Nad synthetase AVENP_RS07865 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AVENP_RS07870 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) AVENP_RS07880 ENOG4105D4P Coproporphyrinogen iii oxidase AVENP_RS07885 ENOG4105DBV ornithine carbamoyltransferase AVENP_RS07890 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase AVENP_RS07905 ENOG4105XJC Two component transcriptional regulator (Winged helix family AVENP_RS07910 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AVENP_RS07915 ENOG4105D52 delta-aminolevulinic acid dehydratase AVENP_RS07925 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) AVENP_RS07980 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase AVENP_RS07985 ENOG4105D9Q decarboxylase (Beta subunit) AVENP_RS07990 ENOG4105PV1 biotin lipoyl attachment domaiN-containing protein AVENP_RS08010 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) AVENP_RS08020 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 AVENP_RS08050 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) AVENP_RS08060 ENOG4105DKF Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity) AVENP_RS08065 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane AVENP_RS08075 ENOG4105EEI dihydropteroate synthase AVENP_RS08090 ENOG4105CFH Aspartokinase AVENP_RS08095 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) AVENP_RS08100 ENOG4105CSA Coproporphyrinogen iii oxidase AVENP_RS08105 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AVENP_RS08110 ENOG4105DGW oligopeptidase A AVENP_RS08130 ENOG4108EU4 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AVENP_RS08240 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) AVENP_RS08250 ENOG4105BZU Histidine kinase AVENP_RS08255 ENOG4105CBS Chea signal transduction histidine kinase AVENP_RS08260 ENOG4108VYJ response regulator receiver protein AVENP_RS08265 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) AVENP_RS08275 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) AVENP_RS08295 ENOG4105CHH sulfate transporter AVENP_RS08300 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) AVENP_RS08315 ENOG4107TPX flagellar hook-associated AVENP_RS08320 ENOG4105BZE flagellar hook protein, FlgE AVENP_RS08335 ENOG4105BZE flagellar hook protein, FlgE AVENP_RS08355 ENOG4105CNU cell division protein FtsK AVENP_RS08360 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AVENP_RS08365 ENOG4108ZP8 Acetolactate synthase small subunit AVENP_RS08370 ENOG4105C7K acetolactate synthase AVENP_RS08375 ENOG4105BZU Histidine kinase AVENP_RS08395 ENOG4105M15 transport protein ExbD AVENP_RS08400 ENOG4105M8K biopolymer transport protein AVENP_RS08410 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) AVENP_RS08415 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS08450 ENOG4105EYH Exonuclease AVENP_RS08460 ENOG41075H3 AraC family transcriptional regulator AVENP_RS08475 ENOG4105D3R alkyl hydroperoxide reductase AVENP_RS08490 ENOG4105VYW UPF0251 protein AVENP_RS08500 ENOG4105C4M (Ubiquinol oxidase) subunit I AVENP_RS08520 ENOG4107QX8 SPFH domain, Band 7 family protein AVENP_RS08525 ENOG4105EBA Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity) AVENP_RS08535 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS08540 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS08555 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AVENP_RS08560 ENOG4105CIY formyltetrahydrofolate deformylase AVENP_RS08565 ENOG4105C6K Malic enzyme AVENP_RS08570 ENOG4108IJ0 Aspartate ammonia-lyase AVENP_RS08575 ENOG4105BZU Histidine kinase AVENP_RS08580 ENOG4108RQS Two component transcriptional regulator (Winged helix family AVENP_RS08600 ENOG4105E2X shikimate dehydrogenase AVENP_RS08620 ENOG4108UHV Lipoprotein AVENP_RS08625 ENOG4106032 Glutathionylspermidine synthase AVENP_RS08640 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) AVENP_RS08680 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) AVENP_RS08695 ENOG4105CVM Molybdenum cofactor synthesis domain protein AVENP_RS08700 ENOG4108PJD permease AVENP_RS08705 ENOG4105CGY Dna recombination protein AVENP_RS08710 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 AVENP_RS08720 ENOG4107YD3 Thioesterase AVENP_RS08735 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS08740 ENOG4105CPC Aldo Keto reductase AVENP_RS08785 ENOG4105CX4 Precorrin-6y C5,15-methyltransferase AVENP_RS08790 ENOG4105CIA precorrin-4 C(11)-methyltransferase AVENP_RS08795 ENOG4108P62 biosynthesis protein (CbiG) AVENP_RS08805 ENOG4105KVH Transcriptional regulator AVENP_RS08810 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein AVENP_RS08815 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein AVENP_RS08820 ENOG4105QNF Outer membrane lipoprotein AVENP_RS08845 ENOG4105EQD regulatoR AVENP_RS08895 ENOG4108RCM Nitroreductase AVENP_RS08905 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AVENP_RS08915 ENOG4108DBC nitroreductase AVENP_RS08920 ENOG4105NF4 modulator of drug activity AVENP_RS08925 ENOG4105KVH Transcriptional regulator AVENP_RS08945 ENOG4105HMI Membrane AVENP_RS08950 ENOG4105DUM transcriptional regulator, lysR family AVENP_RS08960 ENOG4105BZU Histidine kinase AVENP_RS08985 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein AVENP_RS08990 ENOG4105KVH Transcriptional regulator AVENP_RS09015 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA AVENP_RS09030 ENOG4105C5H ABC transporter AVENP_RS09040 ENOG4105EV9 Alpha Beta Hydrolase AVENP_RS09050 ENOG4105CQC Prephenate dehydratase AVENP_RS09060 ENOG4105DKW ABC transporter AVENP_RS09065 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AVENP_RS09100 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain AVENP_RS09110 ENOG4105D06 uba thif-type nad fad binding protein AVENP_RS09120 ENOG4105DZR Type I site-specific deoxyribonuclease AVENP_RS09135 ENOG4105W5Q DNA repair protein (RadC AVENP_RS09145 ENOG4105DWV Homoserine O-trans-acetylase AVENP_RS09170 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) AVENP_RS09175 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) AVENP_RS09220 ENOG4105D00 flagellar biosynthetic protein flhB AVENP_RS09230 ENOG4105CJN penicillin-binding protein AVENP_RS09235 ENOG4105CN7 Flagellar biosynthetic protein FliP AVENP_RS09245 ENOG4105KHC sulfurtransferase AVENP_RS09255 ENOG4105C1P efflux transporter, rnd family, mfp subunit AVENP_RS09285 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AVENP_RS09305 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) AVENP_RS09325 ENOG4105ECC imidazole-glycerol-phosphate dehydratase AVENP_RS09330 ENOG4105K6T rare lipoprotein A AVENP_RS09340 ENOG4105F8V Hydrolase, tatD family AVENP_RS09350 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) AVENP_RS09355 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) AVENP_RS09360 ENOG4105K9Q Binds to the 23S rRNA (By similarity) AVENP_RS09370 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AVENP_RS09375 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) AVENP_RS09380 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) AVENP_RS09385 ENOG4105CUT histidyl-tRNA synthetase AVENP_RS09390 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) AVENP_RS09395 ENOG4105D7W serine acetyltransferase AVENP_RS09405 ENOG4105C1J atp-dependent rna helicase AVENP_RS09420 ENOG4108RZE Tetr family transcriptional regulator AVENP_RS09435 ENOG4105C26 Dehydrogenase AVENP_RS09440 ENOG4108V1U phospholipid-binding protein AVENP_RS09445 ENOG4105T16 Transcriptional regulator (AraC family) AVENP_RS09460 ENOG4108U5N UPF0316 protein AVENP_RS09470 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) AVENP_RS09485 ENOG4105CKD glutathione-regulated potassium-efflux system protein AVENP_RS09490 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase AVENP_RS09495 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AVENP_RS09510 ENOG4105C37 (CBS) domain AVENP_RS09535 ENOG4107QN2 dihydrolipoyl dehydrogenase AVENP_RS09540 ENOG4107QSN dihydrolipoamide acetyltransferase AVENP_RS09545 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) AVENP_RS09550 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) AVENP_RS09555 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) AVENP_RS09560 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) AVENP_RS09565 ENOG4105DSF transport protein AVENP_RS09580 ENOG4105DIT ErfK YbiS YcfS YnhG family protein AVENP_RS09585 ENOG4105C37 (CBS) domain AVENP_RS09620 ENOG4105DJ2 Major Facilitator Superfamily AVENP_RS09625 ENOG4105JXH GntR family transcriptional regulator AVENP_RS09635 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) AVENP_RS09640 ENOG4105DR4 Methyltransferase AVENP_RS09645 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) AVENP_RS09655 ENOG4105ND9 Nitrogenase-associated protein AVENP_RS09660 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) AVENP_RS09685 ENOG4105EI2 Pseudouridine synthase AVENP_RS09700 ENOG410829K Lysine exporter protein (Lyse ygga) AVENP_RS09705 ENOG4105PW4 Sugar fermentation stimulation protein homolog AVENP_RS09730 ENOG4105C0R drug resistance transporter emrb qaca subfamily AVENP_RS09735 ENOG4105CW7 secretion protein, HlyD family AVENP_RS09740 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AVENP_RS09745 ENOG41064MX Tetr family transcriptional regulator AVENP_RS09750 ENOG4105BZU Histidine kinase AVENP_RS09790 ENOG4105FE9 pseudouridine synthase AVENP_RS09840 ENOG4108UYN gCN5-related N-acetyltransferase AVENP_RS09855 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AVENP_RS09860 ENOG4105DN9 Na H antiporter AVENP_RS09865 ENOG4108IYU L-aspartate oxidase AVENP_RS09890 ENOG41076HS cation diffusion facilitator family transporter AVENP_RS09895 ENOG4108ESY Metal dependent phosphohydrolase AVENP_RS09900 ENOG4105F8J Adenylate Guanylate cyclase AVENP_RS09925 ENOG4105C5H ABC transporter AVENP_RS09960 ENOG4105NQN cytochrome C AVENP_RS09980 ENOG4108TMJ glycosyl transferase AVENP_RS09985 ENOG4105K64 Glycosyl transferase, family 2 AVENP_RS10025 ENOG4107TXM Nad-dependent epimerase dehydratase AVENP_RS10035 ENOG4105D2T synthase AVENP_RS10040 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AVENP_RS10050 ENOG4105C30 Nad-dependent epimerase dehydratase AVENP_RS10060 ENOG4105CJT Mannose-1-phosphate guanylyltransferase AVENP_RS10070 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase AVENP_RS10075 ENOG4107UCJ Catalyzes the synthesis of activated sulfate (By similarity) AVENP_RS10120 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) AVENP_RS10125 ENOG4105E1F short-chain dehydrogenase reductase AVENP_RS10130 ENOG4107S6Z Na H antiporter AVENP_RS10135 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AVENP_RS10140 ENOG4106H78 methyltransferase AVENP_RS10145 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) AVENP_RS10155 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AVENP_RS10160 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AVENP_RS10200 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS10205 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) AVENP_RS10210 ENOG41080V7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) AVENP_RS10220 ENOG4108RAC Rubrerythrin AVENP_RS10225 ENOG4108RAC Rubrerythrin AVENP_RS10235 ENOG4105CJR Integral membrane protein (MviN AVENP_RS10240 ENOG4105BZ1 (ABC) transporter AVENP_RS10245 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) AVENP_RS10260 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AVENP_RS10265 ENOG4105CAN Short-chain dehydrogenase reductase Sdr AVENP_RS10270 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase AVENP_RS10275 ENOG4105DZP Membrane-associated zinc metalloprotease AVENP_RS10280 ENOG4105DFA alanine racemase domain protein AVENP_RS10285 ENOG4105VSH 4-oxalocrotonate tautomerase AVENP_RS10295 ENOG4105EGI Transcriptional regulator AVENP_RS10300 ENOG4105DK0 Indole-3-glycerol phosphate synthase AVENP_RS10310 ENOG4105QTX Pfam:UPF0153 AVENP_RS10315 ENOG41060K3 Methyltransferase AVENP_RS10325 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein AVENP_RS10330 ENOG4105DQU oxidoreductase, subunit beta AVENP_RS10340 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AVENP_RS10345 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) AVENP_RS10350 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase AVENP_RS10355 ENOG4105DJV ribulose-phosphate 3-epimerase AVENP_RS10370 ENOG4107VIJ nudix hydrolase AVENP_RS10390 ENOG4105D0M Protease HtpX homolog AVENP_RS10395 ENOG4108V0P LemA family AVENP_RS10400 ENOG4108VPT UPF0234 protein AVENP_RS10405 ENOG4105C2W permease AVENP_RS10410 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) AVENP_RS10420 ENOG4105M08 Membrane AVENP_RS10430 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) AVENP_RS10465 ENOG4107QKV phosphomannomutase AVENP_RS10475 ENOG4107QP8 phosphohexose isomerase AVENP_RS10490 ENOG4105CUB amino acid AVENP_RS10495 ENOG4107FQ9 ethanolamine ammonia-lyase AVENP_RS10500 ENOG4105CPD ethanolamine ammonia-lyase AVENP_RS10515 ENOG4105CGK Exodeoxyribonuclease III AVENP_RS10540 ENOG4105BZU Histidine kinase AVENP_RS10575 ENOG4105BZU Histidine kinase AVENP_RS10600 ENOG4105BZU Histidine kinase AVENP_RS10610 ENOG4105BZU Histidine kinase AVENP_RS10615 ENOG4108IAB Phoh family AVENP_RS10620 ENOG4105DCI Phosphohydrolase AVENP_RS10625 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) AVENP_RS10635 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) AVENP_RS10640 ENOG4105BZU Histidine kinase AVENP_RS10645 ENOG4105C1J atp-dependent rna helicase AVENP_RS10660 ENOG4105BZU Histidine kinase AVENP_RS10680 ENOG4105E7W lamb ycsf family protein AVENP_RS10685 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AVENP_RS10695 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AVENP_RS10700 ENOG4107VQW regulatoR AVENP_RS10705 ENOG4105CQZ Histidine kinase AVENP_RS10735 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) AVENP_RS10740 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS10745 ENOG4105C2C drug resistance transporter, Bcr CflA AVENP_RS10750 ENOG4105CPC Aldo Keto reductase AVENP_RS10755 ENOG4107HP6 Transcriptional regulator AVENP_RS10765 ENOG4105KA0 thioesterase Superfamily protein AVENP_RS10780 ENOG4105RD8 TRAP dicarboxylate transporter AVENP_RS10785 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase AVENP_RS10835 ENOG4108ERU trap dicarboxylate transporter subunit DctP AVENP_RS10840 ENOG4105QPS Monooxygenase AVENP_RS10850 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AVENP_RS10860 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AVENP_RS10880 ENOG4105KHM amidohydrolase 2 AVENP_RS10890 ENOG4105GAK amidohydrolase 2 AVENP_RS10905 ENOG4105JXB ankyrin repeat-containing protein AVENP_RS10910 ENOG4105CH6 catalase AVENP_RS10920 ENOG4105F1S paraquat-inducible protein a AVENP_RS10935 ENOG4105BZU Histidine kinase AVENP_RS10955 ENOG4108Z66 YbaK ebsC protein AVENP_RS10960 ENOG4105F1N DNA alkylation repair AVENP_RS10980 ENOG4105DHT Metal Dependent Phosphohydrolase AVENP_RS10985 ENOG4105CNM Receptor AVENP_RS11000 ENOG4105CYW agmatinase AVENP_RS11005 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) AVENP_RS11015 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AVENP_RS11045 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase AVENP_RS11065 ENOG4108IJ0 Aspartate ammonia-lyase AVENP_RS11070 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS11075 ENOG4105CQZ Histidine kinase AVENP_RS11085 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) AVENP_RS11090 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AVENP_RS11095 ENOG4108YZY peptidylprolyl cis-trans isomerase AVENP_RS11110 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) AVENP_RS11120 ENOG4105M8F Biopolymer transport protein exbD tolR AVENP_RS11125 ENOG4105E02 MotA TolQ exbB proton channel AVENP_RS11130 ENOG41082MC Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) AVENP_RS11135 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) AVENP_RS11140 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) AVENP_RS11145 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) AVENP_RS11150 ENOG4105PQH F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AVENP_RS11155 ENOG4105YF2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity) AVENP_RS11165 ENOG4105FA0 parb-like partition protein AVENP_RS11170 ENOG4107QJE Chromosome Partitioning Protein AVENP_RS11175 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase AVENP_RS11190 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) AVENP_RS11195 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) AVENP_RS11200 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control AVENP_RS11205 ENOG4105K46 50S ribosomal protein l27 AVENP_RS11210 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) AVENP_RS11220 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AVENP_RS11230 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) AVENP_RS11235 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase AVENP_RS11240 ENOG4105DZ1 carboxypeptidase AVENP_RS11245 ENOG4105D0M Protease HtpX homolog AVENP_RS11265 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) AVENP_RS11275 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins AVENP_RS11280 ENOG4108512 Could be involved in insertion of integral membrane proteins into the membrane (By similarity) AVENP_RS11285 ENOG41067YR RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) AVENP_RS11290 ENOG4105VG0 50S ribosomal protein l34 AVENP_RS11295 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AVENP_RS11300 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) AVENP_RS11315 ENOG4107QXP Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) AVENP_RS11320 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AVENP_RS11330 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AVENP_RS11340 ENOG4105E0X reductase AVENP_RS11345 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS11350 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase AVENP_RS11355 ENOG4105BZU Histidine kinase AVENP_RS11360 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase AVENP_RS11375 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AVENP_RS11390 ENOG4108ISG Major Facilitator AVENP_RS11405 ENOG4105DC1 bifunctional purine biosynthesis protein purh AVENP_RS11415 ENOG4107QIK phosphoribosylformylglycinamidine synthase AVENP_RS11425 ENOG4105E4C Lytic transglycosylase catalytic AVENP_RS11440 ENOG4108JPW Aminotransferase AVENP_RS11445 ENOG4108Z6K Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity) AVENP_RS11455 ENOG4105CFH Aspartokinase AVENP_RS11485 ENOG4105CVR type I restriction-modification system AVENP_RS11490 ENOG4107SID ATP-dependent exodnase (exonuclease v) AVENP_RS11565 ENOG4105EUJ GTP cyclohydrolase i AVENP_RS11570 ENOG4105D7N magnesium and cobalt transport protein CorA AVENP_RS11575 ENOG4105D7Q type ii secretion system AVENP_RS11580 ENOG4107QHF type ii secretion system protein e AVENP_RS11595 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) AVENP_RS11600 ENOG4105C0P Mg chelatase subunit ChlI AVENP_RS11610 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AVENP_RS11615 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AVENP_RS11620 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation AVENP_RS11630 ENOG4105CSR polyphosphate kinase 2 AVENP_RS11675 ENOG4107RTG Major Facilitator superfamily AVENP_RS11685 ENOG4105DQ4 alcohol dehydrogenase AVENP_RS11690 ENOG4105CF7 AraC family transcriptional regulator AVENP_RS11695 ENOG4108VWS Yaeq family AVENP_RS11705 ENOG4105C28 cystathionine AVENP_RS11715 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS11720 ENOG4105CQZ Histidine kinase AVENP_RS11730 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AVENP_RS11735 ENOG4105CBS Chea signal transduction histidine kinase AVENP_RS11760 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS11770 ENOG4105D7X high-affinity nickel-transporter AVENP_RS11785 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) AVENP_RS11790 ENOG4106AXJ AraC family transcriptional regulator AVENP_RS11810 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS11825 ENOG4105CHR reductase AVENP_RS11835 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS11845 ENOG4105BZU Histidine kinase AVENP_RS11850 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS11855 ENOG4107XTP (EAL) domain protein AVENP_RS11865 ENOG4105D9P serine threonine protein kinase AVENP_RS11870 ENOG4105BZU Histidine kinase AVENP_RS11885 ENOG4105BZU Histidine kinase AVENP_RS11890 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS11895 ENOG4108IJ6 ABC transporter AVENP_RS11905 ENOG4108I5D sulfate abc transporter AVENP_RS11910 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein AVENP_RS11920 ENOG4108IFG nitrite reductase, (NAD(P)H) AVENP_RS11975 ENOG41084IH F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AVENP_RS11980 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS11990 ENOG4105XJC Two component transcriptional regulator (Winged helix family AVENP_RS12020 ENOG4105D64 Mechanosensitive ion channel AVENP_RS12045 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) AVENP_RS12060 ENOG4105C58 cytochrome c oxidase accessory protein ccog AVENP_RS12065 ENOG4105BZU Histidine kinase AVENP_RS12070 ENOG4107VQW regulatoR AVENP_RS12080 ENOG4107QKV phosphomannomutase AVENP_RS12110 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) AVENP_RS12125 ENOG4105CE1 Ferrous iron transport protein b AVENP_RS12160 ENOG4106PMH Extracellular solute-binding protein family 3 AVENP_RS12165 ENOG4107YTP response regulator receiver protein AVENP_RS12180 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase AVENP_RS12185 ENOG4105CX6 glutaminyL-tRNA synthetase AVENP_RS12215 ENOG41082XB radical SAM domain protein AVENP_RS12220 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) AVENP_RS12230 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AVENP_RS12245 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) AVENP_RS12255 ENOG4105VB9 50S ribosomal protein l28 AVENP_RS12270 ENOG4105CG5 Glycosyl transferase (Group 1 AVENP_RS12295 ENOG4107BJW polysaccharide deacetylase AVENP_RS12310 ENOG4107QQG Dehydrogenase AVENP_RS12330 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding AVENP_RS12335 ENOG4105ECY inositol monophosphatase AVENP_RS12340 ENOG4105BZ8 glutamate synthase AVENP_RS12345 ENOG4105CBC glutamate synthase AVENP_RS12350 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AVENP_RS12360 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AVENP_RS12375 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS12395 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS12410 ENOG4105BZU Histidine kinase AVENP_RS12465 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) AVENP_RS12470 ENOG4105M7K Involved in the transcription termination process (By similarity) AVENP_RS12475 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) AVENP_RS12480 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase AVENP_RS12505 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) AVENP_RS12530 ENOG4107QHF type ii secretion system protein e AVENP_RS12535 ENOG4105GVR general secretion pathway protein D AVENP_RS12575 ENOG4108VAU general secretion pathway protein G AVENP_RS12595 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein AVENP_RS12600 ENOG4105DX0 Hemolysin A AVENP_RS12605 ENOG4105DTN riboflavin biosynthesis protein ribF AVENP_RS12610 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) AVENP_RS12615 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AVENP_RS12625 ENOG4105CQB FAD linked oxidase domain protein AVENP_RS12630 ENOG4107S2Z UPF0761 membrane protein AVENP_RS12675 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AVENP_RS12680 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) AVENP_RS12685 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AVENP_RS12720 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) AVENP_RS12730 ENOG4105CEY Amp-dependent synthetase and ligase AVENP_RS12735 ENOG4105DJG MaoC domain protein dehydratase AVENP_RS12755 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS12760 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) AVENP_RS12765 ENOG4107XWI flavin reductase domain protein, FMN-binding AVENP_RS12790 ENOG4105D7B Flagellar biosynthesis protein flha AVENP_RS12795 ENOG4105DTJ flagellar hook-associated protein AVENP_RS12800 ENOG4108JIR Flagellum-specific ATP synthase AVENP_RS12810 ENOG4105D00 flagellar biosynthetic protein flhB AVENP_RS12825 ENOG4108ZC9 flagellar basal-body rod protein flgc AVENP_RS12830 ENOG41084DA flagellar hook-basal body complex protein fliE AVENP_RS12840 ENOG4107R21 site-determining protein AVENP_RS12845 ENOG4105FZW flagellar biosynthesis regulator FlhF AVENP_RS12870 ENOG4105E14 MotA TolQ exbB proton channel AVENP_RS12895 ENOG4105BZE flagellar hook protein, FlgE AVENP_RS12900 ENOG4105BZE flagellar hook protein, FlgE AVENP_RS12910 ENOG4105DD5 Flagellar motor switch protein AVENP_RS12920 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AVENP_RS12925 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) AVENP_RS12930 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) AVENP_RS12935 ENOG4105CGA flagellar basal-body rod protein FlgG AVENP_RS12945 ENOG4108VYJ response regulator receiver protein AVENP_RS12950 ENOG4105CGA flagellar basal-body rod protein FlgG AVENP_RS12965 ENOG4105V3S An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) AVENP_RS12970 ENOG4105VB6 UPF0109 protein AVENP_RS12975 ENOG4105K5M 30s ribosomal protein S16 AVENP_RS12980 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY AVENP_RS12985 ENOG4105C34 Pseudouridine synthase AVENP_RS12990 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase AVENP_RS13000 ENOG4105EGD dinuclear metal center protein, YbgI family AVENP_RS13005 ENOG4107QIB glycyl-tRNA synthetase, alpha subunit AVENP_RS13015 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AVENP_RS13025 ENOG4105CFP Peptidase U32 AVENP_RS13030 ENOG41080BE Methyl-accepting chemotaxis sensory transducer AVENP_RS13035 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) AVENP_RS13040 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) AVENP_RS13045 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) AVENP_RS13050 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) AVENP_RS13055 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) AVENP_RS13060 ENOG4105F27 Major Facilitator AVENP_RS13090 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS13110 ENOG4105D3R alkyl hydroperoxide reductase AVENP_RS13115 ENOG4105K63 Thioredoxin AVENP_RS13250 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AVENP_RS13255 ENOG4107QIH DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AVENP_RS13260 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) AVENP_RS13265 ENOG4108VZM 50s ribosomal protein L10 AVENP_RS13270 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) AVENP_RS13275 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) AVENP_RS13280 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) AVENP_RS13295 ENOG41086AR 50S ribosomal protein L33 AVENP_RS13300 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) AVENP_RS13330 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) AVENP_RS13335 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) AVENP_RS13340 ENOG4105C3U ABC transporter AVENP_RS13345 ENOG4108JQC penicillin-binding protein 1A AVENP_RS13350 ENOG4105C5F glutamine synthetase AVENP_RS13360 ENOG4108ZEX molybdopterin converting factor, subunit 2 AVENP_RS13370 ENOG4108XUR Pfam:DUF178 AVENP_RS13375 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) AVENP_RS13385 ENOG4105CNI cell division protein FtsW AVENP_RS13390 ENOG4105CJN penicillin-binding protein AVENP_RS13395 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AVENP_RS13450 ENOG4105DDQ anthranilate synthase AVENP_RS13460 ENOG4107QVT Binding-protein-dependent transport systems, inner membrane component AVENP_RS13465 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AVENP_RS13470 ENOG4105BZU Histidine kinase AVENP_RS13515 ENOG4105BZU Histidine kinase AVENP_RS13535 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein AVENP_RS13540 ENOG4105E5Q amino acid AbC transporter AVENP_RS13545 ENOG4106PMH Extracellular solute-binding protein family 3 AVENP_RS13570 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS13580 ENOG4105C26 Dehydrogenase AVENP_RS13585 ENOG4108IV0 ABC, transporter AVENP_RS13590 ENOG4105C0Z ABC transporter AVENP_RS13595 ENOG4105CF8 branched-chain amino acid ABC transporter, permease AVENP_RS13600 ENOG4105C32 Amino acid ABC transporter (Permease) AVENP_RS13630 ENOG4107T5V SNARE associated Golgi AVENP_RS13640 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) AVENP_RS13645 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) AVENP_RS13655 ENOG4107QYE Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) AVENP_RS13660 ENOG4105C7B Threonine dehydratase AVENP_RS13665 ENOG4107WJT it plays a direct role in the translocation of protons across the membrane (By similarity) AVENP_RS13675 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation AVENP_RS13680 ENOG4105CAS nag kinase AVENP_RS13685 ENOG4107QID Threonine synthase AVENP_RS13690 ENOG4108R5F Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) AVENP_RS13695 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) AVENP_RS13710 ENOG4107YV6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) AVENP_RS13720 ENOG4105CVM Molybdenum cofactor synthesis domain protein AVENP_RS13725 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) AVENP_RS13735 ENOG4107SPB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) AVENP_RS13740 ENOG4105CHR reductase AVENP_RS13745 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) AVENP_RS13750 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AVENP_RS13755 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) AVENP_RS13760 ENOG4105K59 histidine triad (HIT) protein AVENP_RS13765 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) AVENP_RS13770 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AVENP_RS13775 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase AVENP_RS13780 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) AVENP_RS13785 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) AVENP_RS13790 ENOG4108JQ1 Dehydrogenase AVENP_RS13795 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) AVENP_RS13800 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AVENP_RS13805 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) AVENP_RS13810 ENOG4105MGB Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) AVENP_RS13815 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) AVENP_RS13825 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) AVENP_RS13835 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AVENP_RS13850 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AVENP_RS13860 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) AVENP_RS13870 ENOG4105YIC Major outer membrane protein AVENP_RS13880 ENOG4105YIC Major outer membrane protein AVENP_RS13885 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) AVENP_RS13900 ENOG4107Z11 Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity) AVENP_RS13950 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i AVENP_RS13955 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) AVENP_RS13960 ENOG4107Z7S Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) AVENP_RS13965 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) AVENP_RS13970 ENOG4105C4R Atp-dependent dna helicase AVENP_RS13975 ENOG4105DUM transcriptional regulator, lysR family AVENP_RS13980 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase AVENP_RS13985 ENOG4105N5T Radical SAM Protein AVENP_RS13990 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase AVENP_RS13995 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) AVENP_RS14000 ENOG4105C3M thioredoxin reductase AVENP_RS14005 ENOG4105K63 Thioredoxin AVENP_RS14010 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AVENP_RS14030 ENOG4107TT5 NLP P60 protein AVENP_RS14035 ENOG4107TT5 NLP P60 protein AVENP_RS14060 ENOG4107YJQ MAF-like protein AVENP_RS14065 ENOG4105CA0 peroxidase AVENP_RS14070 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) AVENP_RS14075 ENOG4105CIH Imidazole acetol-phosphate transaminase AVENP_RS14080 ENOG4105CQC Prephenate dehydratase AVENP_RS14085 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) AVENP_RS14090 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH AVENP_RS14095 ENOG4105CP7 Triose-phosphate isomerase AVENP_RS14100 ENOG4105BZA Phosphoglycerate kinase AVENP_RS14110 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) AVENP_RS14120 ENOG4105C75 arginyL-tRNA synthetase AVENP_RS14125 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) AVENP_RS14130 ENOG4105WMR Protein CrcB homolog AVENP_RS14135 ENOG4105E9Q Acyl-transferase AVENP_RS14145 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I AVENP_RS14150 ENOG4105VR9 phosphoribosylformylglycinamidine synthase AVENP_RS14155 ENOG4105C8V SAICAR synthetase AVENP_RS14160 ENOG4105CN1 protease AVENP_RS14175 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) AVENP_RS14190 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) AVENP_RS14300 ENOG4105C01 Dihydroxy-acid dehydratase AVENP_RS14305 ENOG4105C0H protease AVENP_RS14330 ENOG4105CGD Nad-dependent epimerase dehydratase AVENP_RS14345 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) AVENP_RS14350 ENOG4108HGU Histidine kinase AVENP_RS14380 ENOG4105CIH Imidazole acetol-phosphate transaminase AVENP_RS14395 ENOG41081FY multiple antibiotic resistance (MarC)-related AVENP_RS14400 ENOG4108K7V UPF0284 protein AVENP_RS14405 ENOG4105E3W Two component transcriptional regulator (Winged helix family AVENP_RS14410 ENOG4105BZU Histidine kinase AVENP_RS14420 ENOG4105XJC Two component transcriptional regulator (Winged helix family AVENP_RS14425 ENOG4105BZU Histidine kinase AVENP_RS14430 ENOG4105HDK L-asparaginase AVENP_RS14435 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AVENP_RS14440 ENOG4108IJ0 Aspartate ammonia-lyase AVENP_RS14445 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS14450 ENOG4105E33 succinate dehydrogenase AVENP_RS14455 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) AVENP_RS14460 ENOG4108S24 Fumarate reduCtase AVENP_RS14465 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit AVENP_RS14470 ENOG4105DPX Hydrogenase, large subunit AVENP_RS14475 ENOG4105E3S small subunit AVENP_RS14480 ENOG4105BZU Histidine kinase AVENP_RS14490 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) AVENP_RS14495 ENOG4105K63 Thioredoxin AVENP_RS14510 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) AVENP_RS14525 ENOG4105BZU Histidine kinase AVENP_RS14550 ENOG4105CFG Acts as a chaperone (By similarity) AVENP_RS14555 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ AVENP_RS14560 ENOG4108122 heat-inducible transcription repressor AVENP_RS14575 ENOG4105WH1 Two component transcriptional regulator luxr family AVENP_RS14585 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) AVENP_RS14595 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) AVENP_RS14600 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) AVENP_RS14605 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase AVENP_RS14610 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) AVENP_RS14620 ENOG4105CB5 ATP-dependent DNA helicase recG AVENP_RS14625 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AVENP_RS14630 ENOG4105I03 Flagellin AVENP_RS14630 ENOG4105I03 Flagellin AVENP_RS14670 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AVENP_RS14690 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AVENP_RS14695 ENOG4105DXX methyltransferase AVENP_RS14715 ENOG4105ECJ Glycosyl Transferase AVENP_RS14730 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase AVENP_RS14735 ENOG4105C5R Aminotransferase AVENP_RS14750 ENOG4105CHR reductase AVENP_RS14760 ENOG4105VDT -acetyltransferase AVENP_RS14765 ENOG4107DKY pseudaminic acid biosynthesis-associated protein PseG AVENP_RS14770 ENOG4105D2T synthase AVENP_RS14775 ENOG4105F0R Cytidylyltransferase AVENP_RS14780 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AVENP_RS14785 ENOG4105C5E polysaccharide biosynthesis protein AVENP_RS14795 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) AVENP_RS14800 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) AVENP_RS14820 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) AVENP_RS14835 ENOG4105D4A Cell wall formation (By similarity) AVENP_RS14840 ENOG4105E63 Pfam:DUF178 AVENP_RS14850 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AVENP_RS14855 ENOG4105C8S subunit m AVENP_RS14860 ENOG4105D65 subunit l AVENP_RS14865 ENOG4105M5H NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AVENP_RS14870 ENOG4107UFS subunit j AVENP_RS14875 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AVENP_RS14880 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) AVENP_RS14900 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AVENP_RS14905 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain AVENP_RS14910 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AVENP_RS14915 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain AVENP_RS14920 ENOG4105DHM ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity) AVENP_RS14950 ENOG4105CHH sulfate transporter AVENP_RS14965 ENOG4105C1P efflux transporter, rnd family, mfp subunit AVENP_RS14970 ENOG4105BZS acriflavin resistance protein AVENP_RS14975 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AVENP_RS14980 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) AVENP_RS14990 ENOG4105BZU Histidine kinase AVENP_RS14995 ENOG4105C8J )-transporter AVENP_RS15005 ENOG4105WPN DNA integration recombination invertion protein AVENP_RS15015 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) AVENP_RS15020 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AVENP_RS15025 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) AVENP_RS15045 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) AVENP_RS15055 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family AVENP_RS15060 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding AVENP_RS15080 ENOG4105C58 cytochrome c oxidase accessory protein ccog AVENP_RS15085 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) AVENP_RS15090 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) AVENP_RS15120 ENOG4105C0B DNA polymerase III (alpha subunit) AVENP_RS15125 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) AVENP_RS15140 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AVENP_RS15160 ENOG4105DWA May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate AVENP_RS15165 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) AVENP_RS15170 ENOG4107R4J Chloride channel AVENP_RS15175 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) AVENP_RS15180 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) AVENP_RS15185 ENOG4105F4G Membrane AVENP_RS15195 ENOG4105VYA Uncharacterized conserved protein (DUF2132) AVENP_RS15255 ENOG4105HFZ Membrane AVENP_RS15260 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) AVENP_RS15270 ENOG4105NU9 Preprotein translocase subunit SecG AVENP_RS15280 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) AVENP_RS15285 ENOG4107VCP Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) AVENP_RS15295 ENOG4105D8G Major Facilitator superfamily AVENP_RS15300 ENOG4105EGS Mechanosensitive ion channel AVENP_RS15315 ENOG410802Z Protein of unknown function (DUF328) AVENP_RS15320 ENOG4105K5B UPF0225 protein AVENP_RS15400 ENOG4105CKT filamentous hemagglutinin AVENP_RS15400 ENOG4105CKT filamentous hemagglutinin AVENP_RS15405 ENOG4105D5K Hemolysin activator protein AVENP_RS15410 ENOG4106GFD transport protein AVENP_RS15415 ENOG4105M8K biopolymer transport protein AVENP_RS15420 ENOG4105HB4 Pathways of utilization of iron bound to transferrin, lactoferrin and hemoglobin but not to haemin or citrate where dependent on the TonB system AVENP_RS15435 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) AVENP_RS15440 ENOG4105C26 Dehydrogenase AVENP_RS15445 ENOG4108RW8 Universal stress protein F AVENP_RS15450 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AVENP_RS15460 ENOG41085JF Trap dicarboxylate transporter-dctp subunit AVENP_RS15465 ENOG4108JPW Aminotransferase AVENP_RS15480 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AVENP_RS15485 ENOG4105C26 Dehydrogenase AVENP_RS15490 ENOG4105C7K acetolactate synthase AVENP_RS15495 ENOG4108V0P LemA family AVENP_RS15510 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) AVENP_RS15525 ENOG4105C2C drug resistance transporter, Bcr CflA AVENP_RS15540 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS15545 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase AVENP_RS15585 ENOG4105CBX hi0933 family AVENP_RS15600 ENOG4105C1P efflux transporter, rnd family, mfp subunit AVENP_RS15605 ENOG4105BZS acriflavin resistance protein AVENP_RS15610 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AVENP_RS15640 ENOG4105C6T cysteine synthase AVENP_RS15655 ENOG4105C11 sulfate adenylyltransferase), subunit 2 AVENP_RS15660 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) AVENP_RS15670 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor AVENP_RS15675 ENOG4107RN3 metallophosphoesterase AVENP_RS15700 ENOG4105C8Q Methyl-accepting chemotaxis AVENP_RS15725 ENOG4105CI3 gtp-binding protein typa AVENP_RS15740 ENOG41080IJ Diacylglycerol kinase AVENP_RS15775 ENOG41090JE Utilization Protein AVENP_RS15780 ENOG4105BZ1 (ABC) transporter AVENP_RS15790 ENOG4108WHG pyridoxamine 5'-phosphate AVENP_RS15795 ENOG4107R4I Periplasmic binding protein AVENP_RS15800 ENOG4105EHG Permease protein AVENP_RS15805 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) AVENP_RS15810 ENOG4105D05 Receptor AVENP_RS15820 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AVENP_RS15825 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase AVENP_RS15830 ENOG4107R2U Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) AVENP_RS15835 ENOG4105CSV Glutaminase AVENP_RS15840 ENOG4105EN6 Membrane AVENP_RS15850 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) AVENP_RS15855 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)