locus-tag	class	description
AREALGSMS7_RS00020	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AREALGSMS7_RS00030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AREALGSMS7_RS00035	COG0085	RNA polymerase activity
AREALGSMS7_RS00040	COG0222	ribosome binding
AREALGSMS7_RS00045	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AREALGSMS7_RS00050	COG0081	regulation of translation
AREALGSMS7_RS00055	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AREALGSMS7_RS00105	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS00110	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AREALGSMS7_RS00115	COG1960	acyl-CoA dehydrogenase activity
AREALGSMS7_RS00125	COG1115	amino acid carrier protein
AREALGSMS7_RS00145	COG0301	tRNA thio-modification
AREALGSMS7_RS00145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AREALGSMS7_RS00150	COG1846	Transcriptional regulator
AREALGSMS7_RS00155	COG0778	Nitroreductase
AREALGSMS7_RS00165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AREALGSMS7_RS00170	COG0512	Glutamine amidotransferase of anthranilate synthase
AREALGSMS7_RS00175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AREALGSMS7_RS00180	COG0134	indole-3-glycerol-phosphate synthase activity
AREALGSMS7_RS00185	COG0135	phosphoribosylanthranilate isomerase activity
AREALGSMS7_RS00190	COG0133	tryptophan synthase activity
AREALGSMS7_RS00195	COG0159	tryptophan synthase activity
AREALGSMS7_RS00225	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AREALGSMS7_RS00240	COG3022	response to hydroperoxide
AREALGSMS7_RS00245	COG0564	pseudouridine synthase activity
AREALGSMS7_RS00255	COG1181	Belongs to the D-alanine--D-alanine ligase family
AREALGSMS7_RS00260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AREALGSMS7_RS00265	COG2205	protein histidine kinase activity
AREALGSMS7_RS00270	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS00285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AREALGSMS7_RS00300	COG0799	negative regulation of ribosome biogenesis
AREALGSMS7_RS00305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AREALGSMS7_RS00315	COG4589	Belongs to the CDS family
AREALGSMS7_RS00320	COG0688	phosphatidylethanolamine metabolic process
AREALGSMS7_RS00335	COG2205	protein histidine kinase activity
AREALGSMS7_RS00335	COG3850	Histidine kinase
AREALGSMS7_RS00335	COG4999	Histidine kinase
AREALGSMS7_RS00335	COG3437	response regulator, receiver
AREALGSMS7_RS00340	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS00385	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AREALGSMS7_RS00400	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS00410	COG1609	Transcriptional regulator
AREALGSMS7_RS00420	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS00425	COG0525	valine-tRNA ligase activity
AREALGSMS7_RS00440	COG0436	Aminotransferase
AREALGSMS7_RS00445	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AREALGSMS7_RS00450	COG1595	DNA-templated transcription, initiation
AREALGSMS7_RS00470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AREALGSMS7_RS00475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AREALGSMS7_RS00485	COG1663	tetraacyldisaccharide 4'-kinase activity
AREALGSMS7_RS00490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AREALGSMS7_RS00500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AREALGSMS7_RS00505	COG0740	serine-type endopeptidase activity
AREALGSMS7_RS00520	COG3844	kynureninase activity
AREALGSMS7_RS00525	COG1247	-acetyltransferase
AREALGSMS7_RS00540	COG0671	phosphoesterase, PA-phosphatase related
AREALGSMS7_RS00580	COG3340	Belongs to the peptidase S51 family
AREALGSMS7_RS00620	COG0501	Belongs to the peptidase M48B family
AREALGSMS7_RS00630	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AREALGSMS7_RS00640	COG2226	methyltransferase
AREALGSMS7_RS00660	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AREALGSMS7_RS00665	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AREALGSMS7_RS00670	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AREALGSMS7_RS00675	COG1805	sodium ion transport
AREALGSMS7_RS00680	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AREALGSMS7_RS00690	COG0584	glycerophosphoryl diester phosphodiesterase
AREALGSMS7_RS00705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AREALGSMS7_RS00725	COG4771	TonB-dependent receptor
AREALGSMS7_RS00725	COG4771	TonB-dependent receptor
AREALGSMS7_RS00745	COG1073	alpha beta
AREALGSMS7_RS00760	COG0385	Bile acid
AREALGSMS7_RS00780	COG3537	Alpha-1,2-mannosidase
AREALGSMS7_RS00800	COG1199	ATP-dependent helicase activity
AREALGSMS7_RS00800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AREALGSMS7_RS00805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AREALGSMS7_RS00805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AREALGSMS7_RS00835	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS00840	COG3876	Protein conserved in bacteria
AREALGSMS7_RS00855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AREALGSMS7_RS00865	COG0251	oxidation-reduction process
AREALGSMS7_RS00880	COG0205	6-phosphofructokinase activity
AREALGSMS7_RS00890	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AREALGSMS7_RS00950	COG1331	Highly conserved protein containing a thioredoxin domain
AREALGSMS7_RS00970	COG1312	Catalyzes the dehydration of D-mannonate
AREALGSMS7_RS00975	COG0363	glucosamine-6-phosphate deaminase activity
AREALGSMS7_RS01055	COG4152	abc transporter atp-binding protein
AREALGSMS7_RS01080	COG4263	nitrous-oxide reductase activity
AREALGSMS7_RS01085	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AREALGSMS7_RS01100	COG0439	Biotin carboxylase
AREALGSMS7_RS01105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AREALGSMS7_RS01110	COG1946	Acyl-CoA thioesterase
AREALGSMS7_RS01120	COG0602	queuosine metabolic process
AREALGSMS7_RS01135	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS01140	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS01180	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AREALGSMS7_RS01190	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS01255	COG3437	response regulator, receiver
AREALGSMS7_RS01275	COG4771	TonB-dependent receptor
AREALGSMS7_RS01285	COG3292	Two component regulator propeller
AREALGSMS7_RS01285	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS01285	COG2205	protein histidine kinase activity
AREALGSMS7_RS01290	COG0433	COG0433 Predicted ATPase
AREALGSMS7_RS01315	COG0667	Aldo Keto reductase
AREALGSMS7_RS01320	COG2382	esterase
AREALGSMS7_RS01325	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AREALGSMS7_RS01340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AREALGSMS7_RS01350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AREALGSMS7_RS01380	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS01390	COG0018	arginyl-trna synthetase
AREALGSMS7_RS01400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AREALGSMS7_RS01420	COG0297	glycogen (starch) synthase activity
AREALGSMS7_RS01425	COG0148	phosphopyruvate hydratase activity
AREALGSMS7_RS01430	COG0505	Belongs to the CarA family
AREALGSMS7_RS01435	COG0203	ribosomal protein L17
AREALGSMS7_RS01440	COG0202	RNA polymerase activity
AREALGSMS7_RS01445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AREALGSMS7_RS01450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AREALGSMS7_RS01455	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AREALGSMS7_RS01460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AREALGSMS7_RS01465	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AREALGSMS7_RS01470	COG0201	protein transport
AREALGSMS7_RS01475	COG0200	Binds to the 23S rRNA
AREALGSMS7_RS01480	COG1841	ribosomal large subunit assembly
AREALGSMS7_RS01485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AREALGSMS7_RS01495	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AREALGSMS7_RS01500	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AREALGSMS7_RS01505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AREALGSMS7_RS01510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AREALGSMS7_RS01515	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AREALGSMS7_RS01520	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AREALGSMS7_RS01525	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AREALGSMS7_RS01530	COG0255	Belongs to the universal ribosomal protein uL29 family
AREALGSMS7_RS01535	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AREALGSMS7_RS01540	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AREALGSMS7_RS01545	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AREALGSMS7_RS01550	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AREALGSMS7_RS01555	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AREALGSMS7_RS01560	COG0089	rRNA binding
AREALGSMS7_RS01565	COG0088	Forms part of the polypeptide exit tunnel
AREALGSMS7_RS01570	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AREALGSMS7_RS01575	COG0051	transcription antitermination factor activity, RNA binding
AREALGSMS7_RS01580	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AREALGSMS7_RS01585	COG0049	tRNA binding
AREALGSMS7_RS01590	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AREALGSMS7_RS01595	COG4206	TonB-dependent receptor
AREALGSMS7_RS01595	COG1629	transport
AREALGSMS7_RS01610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AREALGSMS7_RS01620	COG2852	Protein conserved in bacteria
AREALGSMS7_RS01625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AREALGSMS7_RS01650	COG1011	Hydrolase
AREALGSMS7_RS01660	COG2003	Belongs to the UPF0758 family
AREALGSMS7_RS01665	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS01675	COG2514	catechol 2,3-dioxygenase activity
AREALGSMS7_RS01695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AREALGSMS7_RS01710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AREALGSMS7_RS01730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AREALGSMS7_RS01735	COG1410	methionine synthase
AREALGSMS7_RS01735	COG0646	methionine synthase
AREALGSMS7_RS01745	COG0492	ferredoxin-NADP+ reductase activity
AREALGSMS7_RS01750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AREALGSMS7_RS01750	COG1648	precorrin-2 dehydrogenase activity
AREALGSMS7_RS01755	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AREALGSMS7_RS01760	COG2895	sulfate adenylyltransferase (ATP) activity
AREALGSMS7_RS01765	COG0175	sulfate reduction
AREALGSMS7_RS01780	COG1959	2 iron, 2 sulfur cluster binding
AREALGSMS7_RS01790	COG2827	Endonuclease containing a URI domain
AREALGSMS7_RS01795	COG0527	aspartate kinase activity
AREALGSMS7_RS01795	COG0460	homoserine dehydrogenase
AREALGSMS7_RS01805	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AREALGSMS7_RS01810	COG1629	transport
AREALGSMS7_RS01810	COG4206	TonB-dependent receptor
AREALGSMS7_RS01820	COG1428	Deoxynucleoside kinase
AREALGSMS7_RS01825	COG3174	membrane
AREALGSMS7_RS01830	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AREALGSMS7_RS01835	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AREALGSMS7_RS01840	COG4206	TonB-dependent receptor
AREALGSMS7_RS01840	COG1629	transport
AREALGSMS7_RS01845	COG0508	dehydrogenase complex catalyzes the overall conversion of
AREALGSMS7_RS01845	COG0022	dehydrogenase e1 component
AREALGSMS7_RS01855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AREALGSMS7_RS01865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AREALGSMS7_RS01870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AREALGSMS7_RS01875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AREALGSMS7_RS01890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AREALGSMS7_RS01895	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AREALGSMS7_RS01900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AREALGSMS7_RS01910	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS01930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AREALGSMS7_RS01935	COG0563	adenylate kinase activity
AREALGSMS7_RS01940	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AREALGSMS7_RS01945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AREALGSMS7_RS01950	COG0339	signal peptide processing
AREALGSMS7_RS01980	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AREALGSMS7_RS01980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AREALGSMS7_RS01985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AREALGSMS7_RS01995	COG1215	transferase activity, transferring glycosyl groups
AREALGSMS7_RS02005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AREALGSMS7_RS02010	COG1127	ABC transporter
AREALGSMS7_RS02020	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AREALGSMS7_RS02020	COG0662	Cupin 2, conserved barrel domain protein
AREALGSMS7_RS02030	COG0628	permease
AREALGSMS7_RS02035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AREALGSMS7_RS02040	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS02055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AREALGSMS7_RS02060	COG0295	cytidine deaminase activity
AREALGSMS7_RS02075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AREALGSMS7_RS02090	COG3119	arylsulfatase activity
AREALGSMS7_RS02110	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS02115	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS02120	COG4821	SIS domain
AREALGSMS7_RS02135	COG2188	Transcriptional regulator
AREALGSMS7_RS02155	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS02200	COG3275	phosphorelay sensor kinase activity
AREALGSMS7_RS02205	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS02250	COG0285	dihydrofolate synthase activity
AREALGSMS7_RS02265	COG0811	peptide transport
AREALGSMS7_RS02270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AREALGSMS7_RS02280	COG1960	acyl-CoA dehydrogenase activity
AREALGSMS7_RS02285	COG0070	glutamate synthase
AREALGSMS7_RS02285	COG0069	glutamate synthase activity
AREALGSMS7_RS02285	COG0067	glutamate synthase
AREALGSMS7_RS02320	COG3119	arylsulfatase activity
AREALGSMS7_RS02325	COG3119	arylsulfatase activity
AREALGSMS7_RS02330	COG3119	arylsulfatase activity
AREALGSMS7_RS02335	COG0702	epimerase
AREALGSMS7_RS02340	COG4771	TonB-dependent receptor
AREALGSMS7_RS02355	COG3119	arylsulfatase activity
AREALGSMS7_RS02400	COG1629	transport
AREALGSMS7_RS02405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AREALGSMS7_RS02495	COG0321	lipoyl(octanoyl) transferase activity
AREALGSMS7_RS02510	COG0401	homolog of Blt101
AREALGSMS7_RS02515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AREALGSMS7_RS02540	COG0471	metal ion transport
AREALGSMS7_RS02565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AREALGSMS7_RS02570	COG1388	LysM domain
AREALGSMS7_RS02575	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AREALGSMS7_RS02590	COG3186	Phenylalanine-4-hydroxylase
AREALGSMS7_RS02610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AREALGSMS7_RS02615	COG0739	heme binding
AREALGSMS7_RS02635	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AREALGSMS7_RS02645	COG1160	GTP binding
AREALGSMS7_RS02665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AREALGSMS7_RS02670	COG1757	Na H antiporter
AREALGSMS7_RS02675	COG0653	protein targeting
AREALGSMS7_RS02685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AREALGSMS7_RS02695	COG0697	spore germination
AREALGSMS7_RS02700	COG1335	isochorismatase
AREALGSMS7_RS02710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AREALGSMS7_RS02715	COG2318	DinB family
AREALGSMS7_RS02730	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AREALGSMS7_RS02780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AREALGSMS7_RS02790	COG1733	regulation of RNA biosynthetic process
AREALGSMS7_RS02795	COG4584	PFAM Integrase catalytic
AREALGSMS7_RS02800	COG1484	DNA-dependent DNA replication
AREALGSMS7_RS02810	COG1902	pentaerythritol trinitrate reductase activity
AREALGSMS7_RS02815	COG1012	belongs to the aldehyde dehydrogenase family
AREALGSMS7_RS02820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AREALGSMS7_RS02820	COG2207	Transcriptional regulator
AREALGSMS7_RS02825	COG0860	N-Acetylmuramoyl-L-alanine amidase
AREALGSMS7_RS02870	COG0326	Molecular chaperone. Has ATPase activity
AREALGSMS7_RS02880	COG1196	nuclear chromosome segregation
AREALGSMS7_RS02890	COG4584	PFAM Integrase catalytic
AREALGSMS7_RS02895	COG1484	DNA-dependent DNA replication
AREALGSMS7_RS02920	COG2003	Belongs to the UPF0758 family
AREALGSMS7_RS02925	COG0629	single-stranded DNA binding
AREALGSMS7_RS02990	COG0737	Belongs to the 5'-nucleotidase family
AREALGSMS7_RS02995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AREALGSMS7_RS03000	COG0737	Belongs to the 5'-nucleotidase family
AREALGSMS7_RS03035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AREALGSMS7_RS03040	COG3119	arylsulfatase activity
AREALGSMS7_RS03050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AREALGSMS7_RS03080	COG1228	amidohydrolase
AREALGSMS7_RS03095	COG4585	Histidine kinase
AREALGSMS7_RS03130	COG2192	nodulation
AREALGSMS7_RS03135	COG0385	Bile acid
AREALGSMS7_RS03145	COG4993	Dehydrogenase
AREALGSMS7_RS03155	COG0561	phosphatase activity
AREALGSMS7_RS03160	COG4771	TonB-dependent receptor
AREALGSMS7_RS03180	COG3119	arylsulfatase activity
AREALGSMS7_RS03185	COG3119	arylsulfatase activity
AREALGSMS7_RS03190	COG2080	2 iron, 2 sulfur cluster binding
AREALGSMS7_RS03195	COG2010	Cytochrome c
AREALGSMS7_RS03195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AREALGSMS7_RS03215	COG0702	epimerase
AREALGSMS7_RS03220	COG4771	TonB-dependent receptor
AREALGSMS7_RS03225	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS03225	COG3292	Two component regulator propeller
AREALGSMS7_RS03225	COG2205	protein histidine kinase activity
AREALGSMS7_RS03230	COG3119	arylsulfatase activity
AREALGSMS7_RS03245	COG3119	arylsulfatase activity
AREALGSMS7_RS03270	COG3123	guanosine phosphorylase activity
AREALGSMS7_RS03315	COG1484	DNA-dependent DNA replication
AREALGSMS7_RS03320	COG0586	Pfam SNARE associated Golgi protein
AREALGSMS7_RS03335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AREALGSMS7_RS03345	COG1473	amidohydrolase
AREALGSMS7_RS03405	COG1917	Cupin 2, conserved barrel domain protein
AREALGSMS7_RS03405	COG2207	Transcriptional regulator
AREALGSMS7_RS03415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AREALGSMS7_RS03415	COG0515	serine threonine protein kinase
AREALGSMS7_RS03420	COG0612	Peptidase, M16
AREALGSMS7_RS03455	COG0488	(ABC) transporter
AREALGSMS7_RS03465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AREALGSMS7_RS03485	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AREALGSMS7_RS03510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AREALGSMS7_RS03535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AREALGSMS7_RS03540	COG0459	protein refolding
AREALGSMS7_RS03565	COG0138	bifunctional purine biosynthesis protein purh
AREALGSMS7_RS03570	COG1077	Cell shape determining protein MreB Mrl
AREALGSMS7_RS03585	COG0768	penicillin binding
AREALGSMS7_RS03590	COG0772	Belongs to the SEDS family
AREALGSMS7_RS03600	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AREALGSMS7_RS03605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AREALGSMS7_RS03615	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AREALGSMS7_RS03630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AREALGSMS7_RS03645	COG0791	NLP P60 protein
AREALGSMS7_RS03650	COG0658	competence protein
AREALGSMS7_RS03650	COG2333	competence protein COMEC
AREALGSMS7_RS03660	COG3104	oligopeptide transport
AREALGSMS7_RS03680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AREALGSMS7_RS03710	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AREALGSMS7_RS03755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AREALGSMS7_RS03765	COG1621	beta-fructofuranosidase activity
AREALGSMS7_RS03830	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AREALGSMS7_RS03840	COG4771	TonB-dependent receptor
AREALGSMS7_RS03845	COG1609	Transcriptional regulator
AREALGSMS7_RS03850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AREALGSMS7_RS03855	COG1554	hydrolase, family 65, central catalytic
AREALGSMS7_RS03865	COG0584	glycerophosphoryl diester phosphodiesterase
AREALGSMS7_RS03870	COG2081	HI0933 family
AREALGSMS7_RS03875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AREALGSMS7_RS03890	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AREALGSMS7_RS03910	COG1187	pseudouridine synthase activity
AREALGSMS7_RS03960	COG0165	Argininosuccinate lyase
AREALGSMS7_RS03970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AREALGSMS7_RS03980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AREALGSMS7_RS03985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AREALGSMS7_RS03990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AREALGSMS7_RS03995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AREALGSMS7_RS04000	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AREALGSMS7_RS04005	COG0137	argininosuccinate synthase activity
AREALGSMS7_RS04020	COG1215	transferase activity, transferring glycosyl groups
AREALGSMS7_RS04035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AREALGSMS7_RS04040	COG5002	protein histidine kinase activity
AREALGSMS7_RS04045	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS04055	COG1629	transport
AREALGSMS7_RS04080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AREALGSMS7_RS04095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AREALGSMS7_RS04100	COG0463	Glycosyl transferase, family 2
AREALGSMS7_RS04115	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AREALGSMS7_RS04120	COG2363	Small membrane protein
AREALGSMS7_RS04130	COG1522	sequence-specific DNA binding
AREALGSMS7_RS04140	COG0686	Belongs to the AlaDH PNT family
AREALGSMS7_RS04150	COG0495	leucyl-tRNA aminoacylation
AREALGSMS7_RS04155	COG2177	Part of the ABC transporter FtsEX involved in
AREALGSMS7_RS04165	COG1968	undecaprenyl-diphosphatase activity
AREALGSMS7_RS04170	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AREALGSMS7_RS04185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AREALGSMS7_RS04190	COG1054	Belongs to the UPF0176 family
AREALGSMS7_RS04200	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AREALGSMS7_RS04205	COG2226	methyltransferase
AREALGSMS7_RS04230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AREALGSMS7_RS04245	COG0489	protein tyrosine kinase activity
AREALGSMS7_RS04255	COG0492	ferredoxin-NADP+ reductase activity
AREALGSMS7_RS04260	COG0633	Ferredoxin
AREALGSMS7_RS04265	COG1132	(ABC) transporter
AREALGSMS7_RS04285	COG1012	belongs to the aldehyde dehydrogenase family
AREALGSMS7_RS04290	COG2207	Transcriptional regulator
AREALGSMS7_RS04310	COG2610	gluconate transmembrane transporter activity
AREALGSMS7_RS04315	COG0671	phosphoesterase, PA-phosphatase related
AREALGSMS7_RS04325	COG0519	Catalyzes the synthesis of GMP from XMP
AREALGSMS7_RS04335	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AREALGSMS7_RS04350	COG5000	phosphorelay sensor kinase activity
AREALGSMS7_RS04365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AREALGSMS7_RS04375	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS04395	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS04405	COG5002	protein histidine kinase activity
AREALGSMS7_RS04405	COG0784	Response regulator, receiver
AREALGSMS7_RS04450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AREALGSMS7_RS04460	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AREALGSMS7_RS04465	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AREALGSMS7_RS04485	COG4535	Mg2 and Co2 transporter CorC
AREALGSMS7_RS04490	COG0629	single-stranded DNA binding
AREALGSMS7_RS04500	COG0776	regulation of translation
AREALGSMS7_RS04505	COG1530	ribonuclease E activity
AREALGSMS7_RS04530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AREALGSMS7_RS04540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AREALGSMS7_RS04545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AREALGSMS7_RS04650	COG4771	TonB-dependent receptor
AREALGSMS7_RS04655	COG0702	epimerase
AREALGSMS7_RS04680	COG4771	TonB-dependent receptor
AREALGSMS7_RS04725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AREALGSMS7_RS04740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AREALGSMS7_RS04750	COG0297	glycogen (starch) synthase activity
AREALGSMS7_RS04755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AREALGSMS7_RS04760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AREALGSMS7_RS04775	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AREALGSMS7_RS04780	COG0667	Aldo Keto reductase
AREALGSMS7_RS04790	COG0708	Exodeoxyribonuclease III
AREALGSMS7_RS04800	COG0423	glycine-tRNA ligase activity
AREALGSMS7_RS04810	COG1040	competence protein
AREALGSMS7_RS04820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AREALGSMS7_RS04830	COG5001	Diguanylate cyclase
AREALGSMS7_RS04830	COG5002	protein histidine kinase activity
AREALGSMS7_RS04830	COG3447	MASE1 domain protein
AREALGSMS7_RS04835	COG2197	response regulator
AREALGSMS7_RS04865	COG1629	transport
AREALGSMS7_RS04870	COG0166	Belongs to the GPI family
AREALGSMS7_RS04880	COG3483	tryptophan 2,3-dioxygenase activity
AREALGSMS7_RS04890	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AREALGSMS7_RS04895	COG1752	Esterase of the alpha-beta hydrolase superfamily
AREALGSMS7_RS04905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AREALGSMS7_RS04910	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AREALGSMS7_RS04925	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AREALGSMS7_RS04940	COG4206	TonB-dependent receptor
AREALGSMS7_RS04945	COG1381	Involved in DNA repair and RecF pathway recombination
AREALGSMS7_RS04950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AREALGSMS7_RS04955	COG0626	cystathionine gamma-synthase activity
AREALGSMS7_RS04990	COG4771	TonB-dependent receptor
AREALGSMS7_RS05000	COG1609	Transcriptional regulator
AREALGSMS7_RS05025	COG0429	hydrolase of the alpha beta-hydrolase fold
AREALGSMS7_RS05035	COG0659	secondary active sulfate transmembrane transporter activity
AREALGSMS7_RS05055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AREALGSMS7_RS05060	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AREALGSMS7_RS05065	COG4953	penicillin-binding protein 1C
AREALGSMS7_RS05070	COG2329	Antibiotic biosynthesis monooxygenase
AREALGSMS7_RS05090	COG2373	Large extracellular alpha-helical protein
AREALGSMS7_RS05100	COG0662	Cupin 2, conserved barrel domain protein
AREALGSMS7_RS05105	COG1012	belongs to the aldehyde dehydrogenase family
AREALGSMS7_RS05135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AREALGSMS7_RS05145	COG4221	oxidoreductase activity
AREALGSMS7_RS05150	COG0714	Associated with various cellular activities
AREALGSMS7_RS05170	COG2304	oxidoreductase activity
AREALGSMS7_RS05195	COG0659	secondary active sulfate transmembrane transporter activity
AREALGSMS7_RS05210	COG0659	secondary active sulfate transmembrane transporter activity
AREALGSMS7_RS05215	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AREALGSMS7_RS05235	COG1538	Outer membrane efflux protein
AREALGSMS7_RS05245	COG2954	triphosphatase activity
AREALGSMS7_RS05250	COG0702	epimerase
AREALGSMS7_RS05255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AREALGSMS7_RS05260	COG0469	pyruvate kinase activity
AREALGSMS7_RS05270	COG0571	ribonuclease III activity
AREALGSMS7_RS05275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AREALGSMS7_RS05280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AREALGSMS7_RS05285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AREALGSMS7_RS05290	COG3341	Caulimovirus viroplasmin
AREALGSMS7_RS05290	COG0328	RNA-DNA hybrid ribonuclease activity
AREALGSMS7_RS05320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AREALGSMS7_RS05320	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AREALGSMS7_RS05325	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AREALGSMS7_RS05330	COG0720	synthase
AREALGSMS7_RS05355	COG0534	Mate efflux family protein
AREALGSMS7_RS05420	COG0860	N-Acetylmuramoyl-L-alanine amidase
AREALGSMS7_RS05485	COG2003	Belongs to the UPF0758 family
AREALGSMS7_RS05505	COG0202	RNA polymerase activity
AREALGSMS7_RS05585	COG0629	single-stranded DNA binding
AREALGSMS7_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS05610	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS05640	COG0667	Aldo Keto reductase
AREALGSMS7_RS05660	COG3119	arylsulfatase activity
AREALGSMS7_RS05665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AREALGSMS7_RS05695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AREALGSMS7_RS05705	COG2186	Transcriptional regulator
AREALGSMS7_RS05710	COG0702	epimerase
AREALGSMS7_RS05715	COG4771	TonB-dependent receptor
AREALGSMS7_RS05730	COG4771	TonB-dependent receptor
AREALGSMS7_RS05735	COG0702	epimerase
AREALGSMS7_RS05745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AREALGSMS7_RS05750	COG3119	arylsulfatase activity
AREALGSMS7_RS05750	COG3408	Glycogen debranching enzyme
AREALGSMS7_RS05755	COG3119	arylsulfatase activity
AREALGSMS7_RS05760	COG3119	arylsulfatase activity
AREALGSMS7_RS05785	COG1858	cytochrome C peroxidase
AREALGSMS7_RS05825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AREALGSMS7_RS05830	COG1127	ABC transporter
AREALGSMS7_RS05855	COG1360	Flagellar Motor Protein
AREALGSMS7_RS05875	COG0813	purine-nucleoside phosphorylase activity
AREALGSMS7_RS05880	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AREALGSMS7_RS05900	COG0210	DNA helicase
AREALGSMS7_RS05905	COG2885	chlorophyll binding
AREALGSMS7_RS05905	COG3047	cAMP biosynthetic process
AREALGSMS7_RS05910	COG1074	ATP-dependent DNA helicase activity
AREALGSMS7_RS05930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AREALGSMS7_RS05940	COG1435	thymidine kinase activity
AREALGSMS7_RS05945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AREALGSMS7_RS05950	COG1970	mechanosensitive ion channel activity
AREALGSMS7_RS05955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AREALGSMS7_RS05965	COG3842	ATPase activity
AREALGSMS7_RS05970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AREALGSMS7_RS05990	COG0439	Biotin carboxylase
AREALGSMS7_RS05995	COG0511	ligase activity, forming carbon-carbon bonds
AREALGSMS7_RS06000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AREALGSMS7_RS06005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AREALGSMS7_RS06015	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AREALGSMS7_RS06065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AREALGSMS7_RS06085	COG4771	TonB-dependent receptor
AREALGSMS7_RS06095	COG2217	Heavy metal translocating P-type atpase
AREALGSMS7_RS06135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AREALGSMS7_RS06165	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS06175	COG0584	glycerophosphoryl diester phosphodiesterase
AREALGSMS7_RS06190	COG3250	beta-galactosidase activity
AREALGSMS7_RS06210	COG4771	TonB-dependent receptor
AREALGSMS7_RS06235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AREALGSMS7_RS06250	COG0446	pyridine nucleotide-disulphide oxidoreductase
AREALGSMS7_RS06270	COG1611	Belongs to the LOG family
AREALGSMS7_RS06275	COG0842	Transport permease protein
AREALGSMS7_RS06275	COG1129	ABC transporter
AREALGSMS7_RS06280	COG0842	Transport permease protein
AREALGSMS7_RS06285	COG1131	(ABC) transporter
AREALGSMS7_RS06290	COG1131	(ABC) transporter
AREALGSMS7_RS06300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AREALGSMS7_RS06310	COG1309	transcriptional regulator
AREALGSMS7_RS06325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AREALGSMS7_RS06335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AREALGSMS7_RS06350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AREALGSMS7_RS06365	COG0385	Bile acid
AREALGSMS7_RS06395	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AREALGSMS7_RS06400	COG3119	arylsulfatase activity
AREALGSMS7_RS06405	COG3119	arylsulfatase activity
AREALGSMS7_RS06420	COG1131	(ABC) transporter
AREALGSMS7_RS06485	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AREALGSMS7_RS06490	COG0732	type I restriction modification DNA specificity domain
AREALGSMS7_RS06495	COG4249	Peptidase C14 caspase catalytic subunit p20
AREALGSMS7_RS06520	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AREALGSMS7_RS06530	COG3119	arylsulfatase activity
AREALGSMS7_RS06535	COG1472	Belongs to the glycosyl hydrolase 3 family
AREALGSMS7_RS06565	COG0702	epimerase
AREALGSMS7_RS06570	COG4771	TonB-dependent receptor
AREALGSMS7_RS06590	COG0346	lactoylglutathione lyase activity
AREALGSMS7_RS06595	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AREALGSMS7_RS06600	COG4591	ABC-type transport system involved in lipoprotein release permease component
AREALGSMS7_RS06630	COG0481	GTPase activity
AREALGSMS7_RS06640	COG3263	regulation of cellular component size
AREALGSMS7_RS06645	COG0475	glutathione-regulated potassium exporter activity
AREALGSMS7_RS06650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AREALGSMS7_RS06655	COG1404	Belongs to the peptidase S8 family
AREALGSMS7_RS06665	COG2988	succinylglutamate desuccinylase activity
AREALGSMS7_RS06675	COG0594	ribonuclease P activity
AREALGSMS7_RS06705	COG4948	Mandelate Racemase Muconate Lactonizing
AREALGSMS7_RS06710	COG2610	gluconate transmembrane transporter activity
AREALGSMS7_RS06715	COG3386	PFAM SMP-30 Gluconolaconase
AREALGSMS7_RS06720	COG0791	NLP P60 protein
AREALGSMS7_RS06735	COG2153	protein acetylation
AREALGSMS7_RS06740	COG0698	ribose 5-phosphate isomerase
AREALGSMS7_RS06745	COG0557	exoribonuclease II activity
AREALGSMS7_RS06790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AREALGSMS7_RS06815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AREALGSMS7_RS06825	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AREALGSMS7_RS06830	COG0445	tRNA wobble uridine modification
AREALGSMS7_RS06950	COG1091	dTDP-4-dehydrorhamnose reductase activity
AREALGSMS7_RS06975	COG4942	peptidase
AREALGSMS7_RS06980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AREALGSMS7_RS06995	COG0791	NLP P60 protein
AREALGSMS7_RS06995	COG1388	LysM domain
AREALGSMS7_RS07000	COG0126	phosphoglycerate kinase activity
AREALGSMS7_RS07020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AREALGSMS7_RS07060	COG0356	it plays a direct role in the translocation of protons across the membrane
AREALGSMS7_RS07065	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AREALGSMS7_RS07070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AREALGSMS7_RS07075	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AREALGSMS7_RS07080	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AREALGSMS7_RS07085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AREALGSMS7_RS07095	COG0756	dUTP diphosphatase activity
AREALGSMS7_RS07115	COG0656	L-ascorbic acid biosynthetic process
AREALGSMS7_RS07120	COG1607	acyl-coa hydrolase
AREALGSMS7_RS07135	COG4771	TonB-dependent receptor
AREALGSMS7_RS07140	COG0180	Tryptophanyl-tRNA synthetase
AREALGSMS7_RS07165	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AREALGSMS7_RS07170	COG1054	Belongs to the UPF0176 family
AREALGSMS7_RS07175	COG1774	PSP1 C-terminal conserved region
AREALGSMS7_RS07185	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AREALGSMS7_RS07190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AREALGSMS7_RS07210	COG0436	Aminotransferase
AREALGSMS7_RS07220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AREALGSMS7_RS07230	COG1053	succinate dehydrogenase
AREALGSMS7_RS07250	COG0006	proline dipeptidase activity
AREALGSMS7_RS07270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AREALGSMS7_RS07285	COG0316	Belongs to the HesB IscA family
AREALGSMS7_RS07290	COG0719	Fe-S assembly protein
AREALGSMS7_RS07295	COG0396	ATPase activity
AREALGSMS7_RS07305	COG0719	Fe-S assembly protein
AREALGSMS7_RS07310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AREALGSMS7_RS07315	COG2166	iron-sulfur cluster assembly
AREALGSMS7_RS07320	COG2151	metal-sulfur cluster biosynthetic enzyme
AREALGSMS7_RS07335	COG2819	hydrolase of the alpha beta superfamily
AREALGSMS7_RS07340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AREALGSMS7_RS07360	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AREALGSMS7_RS07375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AREALGSMS7_RS07395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AREALGSMS7_RS07400	COG1253	flavin adenine dinucleotide binding
AREALGSMS7_RS07415	COG0113	porphobilinogen synthase activity
AREALGSMS7_RS07420	COG3012	SEC-C Motif Domain Protein
AREALGSMS7_RS07425	COG0408	coproporphyrinogen oxidase activity
AREALGSMS7_RS07440	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AREALGSMS7_RS07450	COG0181	hydroxymethylbilane synthase activity
AREALGSMS7_RS07455	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AREALGSMS7_RS07480	COG1247	-acetyltransferase
AREALGSMS7_RS07525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AREALGSMS7_RS07540	COG1981	membrane
AREALGSMS7_RS07550	COG1024	Enoyl-CoA hydratase
AREALGSMS7_RS07565	COG1418	mRNA catabolic process
AREALGSMS7_RS07595	COG0793	Belongs to the peptidase S41A family
AREALGSMS7_RS07605	COG2095	MarC family integral membrane protein
AREALGSMS7_RS07615	COG3275	phosphorelay sensor kinase activity
AREALGSMS7_RS07620	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS07630	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS07630	COG2205	protein histidine kinase activity
AREALGSMS7_RS07630	COG3292	Two component regulator propeller
AREALGSMS7_RS07640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AREALGSMS7_RS07640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AREALGSMS7_RS07670	COG2211	Major facilitator Superfamily
AREALGSMS7_RS07675	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS07705	COG5658	integral membrane protein
AREALGSMS7_RS07710	COG1561	YicC-like family, N-terminal region
AREALGSMS7_RS07715	COG0194	GDP metabolic process
AREALGSMS7_RS07720	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AREALGSMS7_RS07740	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AREALGSMS7_RS07750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AREALGSMS7_RS07755	COG0590	tRNA wobble adenosine to inosine editing
AREALGSMS7_RS07765	COG1278	Cold shock
AREALGSMS7_RS07780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AREALGSMS7_RS07785	COG4771	TonB-dependent receptor
AREALGSMS7_RS07800	COG3344	reverse transcriptase
AREALGSMS7_RS07820	COG1309	transcriptional regulator
AREALGSMS7_RS07845	COG4771	TonB-dependent receptor
AREALGSMS7_RS07870	COG2363	Small membrane protein
AREALGSMS7_RS07890	COG1999	signal sequence binding
AREALGSMS7_RS07895	COG0750	zinc metalloprotease
AREALGSMS7_RS07925	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS07925	COG2205	protein histidine kinase activity
AREALGSMS7_RS07925	COG3292	Two component regulator propeller
AREALGSMS7_RS07925	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS07925	COG3292	Two component regulator propeller
AREALGSMS7_RS07925	COG2205	protein histidine kinase activity
AREALGSMS7_RS07930	COG4771	TonB-dependent receptor
AREALGSMS7_RS07935	COG0702	epimerase
AREALGSMS7_RS07970	COG3177	Filamentation induced by cAMP protein fic
AREALGSMS7_RS08015	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AREALGSMS7_RS08050	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AREALGSMS7_RS08075	COG3344	reverse transcriptase
AREALGSMS7_RS08095	COG3422	double-strand break repair
AREALGSMS7_RS08110	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS08125	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AREALGSMS7_RS08130	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AREALGSMS7_RS08150	COG2755	lipolytic protein G-D-S-L family
AREALGSMS7_RS08150	COG0657	acetylesterase activity
AREALGSMS7_RS08155	COG2755	lipolytic protein G-D-S-L family
AREALGSMS7_RS08160	COG4677	pectinesterase activity
AREALGSMS7_RS08170	COG2721	sulfolactate sulfo-lyase activity
AREALGSMS7_RS08175	COG0246	Mannitol dehydrogenase
AREALGSMS7_RS08180	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS08185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AREALGSMS7_RS08190	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AREALGSMS7_RS08195	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AREALGSMS7_RS08200	COG3119	arylsulfatase activity
AREALGSMS7_RS08225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AREALGSMS7_RS08245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AREALGSMS7_RS08250	COG0657	acetylesterase activity
AREALGSMS7_RS08250	COG2755	lipolytic protein G-D-S-L family
AREALGSMS7_RS08280	COG4206	TonB-dependent receptor
AREALGSMS7_RS08280	COG1629	transport
AREALGSMS7_RS08290	COG2205	protein histidine kinase activity
AREALGSMS7_RS08290	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS08290	COG3292	Two component regulator propeller
AREALGSMS7_RS08310	COG0702	epimerase
AREALGSMS7_RS08315	COG4771	TonB-dependent receptor
AREALGSMS7_RS08325	COG1595	DNA-templated transcription, initiation
AREALGSMS7_RS08335	COG4948	Mandelate Racemase Muconate Lactonizing
AREALGSMS7_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS08350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AREALGSMS7_RS08355	COG3119	arylsulfatase activity
AREALGSMS7_RS08360	COG0179	Fumarylacetoacetate (FAA) hydrolase
AREALGSMS7_RS08370	COG2755	lipolytic protein G-D-S-L family
AREALGSMS7_RS08370	COG0657	acetylesterase activity
AREALGSMS7_RS08385	COG3119	arylsulfatase activity
AREALGSMS7_RS08395	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS08400	COG0738	Major facilitator superfamily
AREALGSMS7_RS08405	COG3254	rhamnose metabolic process
AREALGSMS7_RS08415	COG1304	FMN binding
AREALGSMS7_RS08425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AREALGSMS7_RS08450	COG1069	ribulokinase activity
AREALGSMS7_RS08470	COG0667	Aldo Keto reductase
AREALGSMS7_RS08485	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AREALGSMS7_RS08510	COG2272	Belongs to the type-B carboxylesterase lipase family
AREALGSMS7_RS08515	COG2755	lipolytic protein G-D-S-L family
AREALGSMS7_RS08515	COG0657	acetylesterase activity
AREALGSMS7_RS08535	COG1349	DNA-binding transcription factor activity
AREALGSMS7_RS08550	COG4821	SIS domain
AREALGSMS7_RS08580	COG3384	dioxygenase
AREALGSMS7_RS08590	COG3059	membrane
AREALGSMS7_RS08605	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AREALGSMS7_RS08755	COG0024	Methionine aminopeptidase
AREALGSMS7_RS08795	COG0010	Belongs to the arginase family
AREALGSMS7_RS08800	COG1899	peptidyl-lysine modification to peptidyl-hypusine
AREALGSMS7_RS08820	COG4067	protein conserved in archaea
AREALGSMS7_RS08820	COG0189	ligase activity
AREALGSMS7_RS08845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AREALGSMS7_RS08855	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS08855	COG0516	GMP reductase activity
AREALGSMS7_RS08870	COG0346	lactoylglutathione lyase activity
AREALGSMS7_RS08895	COG0629	single-stranded DNA binding
AREALGSMS7_RS08910	COG1528	Iron-storage protein
AREALGSMS7_RS08925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AREALGSMS7_RS08925	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AREALGSMS7_RS08940	COG0792	nuclease activity
AREALGSMS7_RS08955	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AREALGSMS7_RS08960	COG2010	Cytochrome c
AREALGSMS7_RS08965	COG3256	nitric oxide reductase
AREALGSMS7_RS08970	COG0714	Associated with various cellular activities
AREALGSMS7_RS08975	COG4548	von Willebrand factor, type A
AREALGSMS7_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS09015	COG3386	PFAM SMP-30 Gluconolaconase
AREALGSMS7_RS09035	COG2197	response regulator
AREALGSMS7_RS09050	COG2308	Evidence 4 Homologs of previously reported genes of
AREALGSMS7_RS09050	COG2307	Protein conserved in bacteria
AREALGSMS7_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS09125	COG3609	addiction module antidote protein, CC2985 family
AREALGSMS7_RS09145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AREALGSMS7_RS09150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AREALGSMS7_RS09155	COG0193	aminoacyl-tRNA hydrolase activity
AREALGSMS7_RS09165	COG1404	Belongs to the peptidase S8 family
AREALGSMS7_RS09165	COG4935	Belongs to the peptidase S8 family
AREALGSMS7_RS09170	COG0196	riboflavin kinase activity
AREALGSMS7_RS09185	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AREALGSMS7_RS09205	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AREALGSMS7_RS09210	COG2239	Acts as a magnesium transporter
AREALGSMS7_RS09230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AREALGSMS7_RS09235	COG0346	lactoylglutathione lyase activity
AREALGSMS7_RS09250	COG1484	DNA-dependent DNA replication
AREALGSMS7_RS09265	COG0527	aspartate kinase activity
AREALGSMS7_RS09275	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AREALGSMS7_RS09285	COG2205	protein histidine kinase activity
AREALGSMS7_RS09285	COG0784	Response regulator, receiver
AREALGSMS7_RS09300	COG2723	6-phospho-beta-galactosidase activity
AREALGSMS7_RS09315	COG4206	TonB-dependent receptor
AREALGSMS7_RS09315	COG1629	transport
AREALGSMS7_RS09325	COG1595	DNA-templated transcription, initiation
AREALGSMS7_RS09335	COG4771	TonB-dependent receptor
AREALGSMS7_RS09345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AREALGSMS7_RS09350	COG1960	acyl-CoA dehydrogenase activity
AREALGSMS7_RS09355	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AREALGSMS7_RS09360	COG3119	arylsulfatase activity
AREALGSMS7_RS09370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AREALGSMS7_RS09375	COG0228	four-way junction DNA binding
AREALGSMS7_RS09390	COG3118	belongs to the thioredoxin family
AREALGSMS7_RS09410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AREALGSMS7_RS09415	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS09420	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS09440	COG1333	cytochrome c biogenesis protein
AREALGSMS7_RS09440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AREALGSMS7_RS09490	COG3609	addiction module antidote protein, CC2985 family
AREALGSMS7_RS09615	COG3385	transposase activity
AREALGSMS7_RS09640	COG1051	belongs to the nudix hydrolase family
AREALGSMS7_RS09765	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS09800	COG2423	ornithine cyclodeaminase activity
AREALGSMS7_RS09810	COG3119	arylsulfatase activity
AREALGSMS7_RS09815	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS09855	COG3734	2-keto-3-deoxy-galactonokinase
AREALGSMS7_RS09860	COG0800	Aldolase
AREALGSMS7_RS09870	COG2706	6-phosphogluconolactonase activity
AREALGSMS7_RS09875	COG3119	arylsulfatase activity
AREALGSMS7_RS09880	COG3119	arylsulfatase activity
AREALGSMS7_RS09905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AREALGSMS7_RS09915	COG2186	Transcriptional regulator
AREALGSMS7_RS09940	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AREALGSMS7_RS09950	COG0702	epimerase
AREALGSMS7_RS09955	COG4771	TonB-dependent receptor
AREALGSMS7_RS09965	COG4771	TonB-dependent receptor
AREALGSMS7_RS09980	COG4771	TonB-dependent receptor
AREALGSMS7_RS09990	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS10025	COG3718	enzyme involved in inositol metabolism
AREALGSMS7_RS10030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AREALGSMS7_RS10035	COG3962	Belongs to the TPP enzyme family
AREALGSMS7_RS10040	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AREALGSMS7_RS10045	COG1012	belongs to the aldehyde dehydrogenase family
AREALGSMS7_RS10050	COG1082	Xylose isomerase domain protein TIM barrel
AREALGSMS7_RS10055	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS10070	COG4771	TonB-dependent receptor
AREALGSMS7_RS10075	COG0702	epimerase
AREALGSMS7_RS10080	COG0833	amino acid
AREALGSMS7_RS10100	COG0519	Catalyzes the synthesis of GMP from XMP
AREALGSMS7_RS10100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AREALGSMS7_RS10105	COG3537	Alpha-1,2-mannosidase
AREALGSMS7_RS10110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AREALGSMS7_RS10115	COG5002	protein histidine kinase activity
AREALGSMS7_RS10120	COG2201	protein-glutamate methylesterase activity
AREALGSMS7_RS10130	COG1904	glucuronate isomerase
AREALGSMS7_RS10140	COG1609	Transcriptional regulator
AREALGSMS7_RS10145	COG4771	TonB-dependent receptor
AREALGSMS7_RS10160	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS10170	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS10195	COG4771	TonB-dependent receptor
AREALGSMS7_RS10220	COG1012	belongs to the aldehyde dehydrogenase family
AREALGSMS7_RS10225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AREALGSMS7_RS10225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AREALGSMS7_RS10230	COG2271	Major facilitator Superfamily
AREALGSMS7_RS10245	COG1063	alcohol dehydrogenase
AREALGSMS7_RS10250	COG0477	Major facilitator Superfamily
AREALGSMS7_RS10260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AREALGSMS7_RS10260	COG2022	thiamine diphosphate biosynthetic process
AREALGSMS7_RS10280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AREALGSMS7_RS10285	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AREALGSMS7_RS10290	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AREALGSMS7_RS10295	COG3537	Alpha-1,2-mannosidase
AREALGSMS7_RS10300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AREALGSMS7_RS10300	COG1648	precorrin-2 dehydrogenase activity
AREALGSMS7_RS10305	COG1070	Carbohydrate kinase
AREALGSMS7_RS10310	COG2115	Belongs to the xylose isomerase family
AREALGSMS7_RS10315	COG2852	Protein conserved in bacteria
AREALGSMS7_RS10320	COG1609	Transcriptional regulator
AREALGSMS7_RS10335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AREALGSMS7_RS10340	COG0589	response to stress
AREALGSMS7_RS10365	COG0348	domain, Protein
AREALGSMS7_RS10395	COG2217	Heavy metal translocating P-type atpase
AREALGSMS7_RS10400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AREALGSMS7_RS10420	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AREALGSMS7_RS10425	COG0010	Belongs to the arginase family
AREALGSMS7_RS10445	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AREALGSMS7_RS10450	COG1228	amidohydrolase
AREALGSMS7_RS10455	COG2986	histidine ammonia-lyase
AREALGSMS7_RS10460	COG0583	DNA-binding transcription factor activity
AREALGSMS7_RS10500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AREALGSMS7_RS10510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AREALGSMS7_RS10575	COG2239	Acts as a magnesium transporter
AREALGSMS7_RS10605	COG1132	(ABC) transporter
AREALGSMS7_RS10640	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS10660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AREALGSMS7_RS10665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AREALGSMS7_RS10710	COG0604	alcohol dehydrogenase
AREALGSMS7_RS10730	COG2814	Major facilitator Superfamily
AREALGSMS7_RS10740	COG1519	Transferase
AREALGSMS7_RS10750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AREALGSMS7_RS10775	COG0508	dehydrogenase complex catalyzes the overall conversion of
AREALGSMS7_RS10785	COG0084	hydrolase, TatD family'
AREALGSMS7_RS10790	COG0252	asparaginase activity
AREALGSMS7_RS10800	COG0811	peptide transport
AREALGSMS7_RS10830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AREALGSMS7_RS10835	COG0017	Asparaginyl-tRNA synthetase
AREALGSMS7_RS10845	COG0233	cytoplasmic translational termination
AREALGSMS7_RS10850	COG0528	UMP kinase activity
AREALGSMS7_RS10860	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AREALGSMS7_RS10865	COG0052	Belongs to the universal ribosomal protein uS2 family
AREALGSMS7_RS10870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AREALGSMS7_RS10875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AREALGSMS7_RS10890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AREALGSMS7_RS10890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AREALGSMS7_RS10895	COG1446	asparaginase
AREALGSMS7_RS10905	COG1408	metallophosphoesterase
AREALGSMS7_RS10970	COG3384	dioxygenase
AREALGSMS7_RS10980	COG1733	regulation of RNA biosynthetic process
AREALGSMS7_RS10990	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS10995	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS11005	COG1733	regulation of RNA biosynthetic process
AREALGSMS7_RS11010	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS11015	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS11030	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS11035	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS11040	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS11065	COG0779	Required for maturation of 30S ribosomal subunits
AREALGSMS7_RS11070	COG0195	Participates in both transcription termination and antitermination
AREALGSMS7_RS11075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AREALGSMS7_RS11090	COG0437	4 iron, 4 sulfur cluster binding
AREALGSMS7_RS11115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AREALGSMS7_RS11120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AREALGSMS7_RS11135	COG2255	four-way junction helicase activity
AREALGSMS7_RS11145	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AREALGSMS7_RS11150	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AREALGSMS7_RS11155	COG0281	malic enzyme
AREALGSMS7_RS11155	COG0280	phosphate acetyltransferase
AREALGSMS7_RS11160	COG0632	four-way junction helicase activity
AREALGSMS7_RS11170	COG0509	glycine decarboxylation via glycine cleavage system
AREALGSMS7_RS11185	COG0109	protoheme IX farnesyltransferase activity
AREALGSMS7_RS11210	COG1999	signal sequence binding
AREALGSMS7_RS11215	COG2322	membrane
AREALGSMS7_RS11225	COG1136	(ABC) transporter
AREALGSMS7_RS11225	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS11230	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS11230	COG1136	(ABC) transporter
AREALGSMS7_RS11235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AREALGSMS7_RS11240	COG1136	(ABC) transporter
AREALGSMS7_RS11245	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS11245	COG1136	(ABC) transporter
AREALGSMS7_RS11250	COG1136	(ABC) transporter
AREALGSMS7_RS11250	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS11265	COG1214	PFAM Peptidase M22, glycoprotease
AREALGSMS7_RS11270	COG0668	transmembrane transport
AREALGSMS7_RS11280	COG0316	Belongs to the HesB IscA family
AREALGSMS7_RS11280	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AREALGSMS7_RS11295	COG3275	phosphorelay sensor kinase activity
AREALGSMS7_RS11300	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS11305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AREALGSMS7_RS11310	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AREALGSMS7_RS11340	COG2949	membrane
AREALGSMS7_RS11370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AREALGSMS7_RS11375	COG2814	Major facilitator Superfamily
AREALGSMS7_RS11380	COG2217	Heavy metal translocating P-type atpase
AREALGSMS7_RS11395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AREALGSMS7_RS11405	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AREALGSMS7_RS11430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AREALGSMS7_RS11435	COG0205	6-phosphofructokinase activity
AREALGSMS7_RS11440	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AREALGSMS7_RS11455	COG0058	SHG alpha-glucan phosphorylase activity
AREALGSMS7_RS11475	COG1301	dicarboxylic acid transport
AREALGSMS7_RS11480	COG1830	Aldolase
AREALGSMS7_RS11490	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AREALGSMS7_RS11495	COG1252	NADH dehydrogenase
AREALGSMS7_RS11585	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AREALGSMS7_RS11595	COG1629	transport
AREALGSMS7_RS11620	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AREALGSMS7_RS11630	COG2217	Heavy metal translocating P-type atpase
AREALGSMS7_RS11635	COG2132	Multicopper oxidase
AREALGSMS7_RS11640	COG0531	amino acid
AREALGSMS7_RS11670	COG2226	methyltransferase
AREALGSMS7_RS11700	COG0640	Transcriptional regulator
AREALGSMS7_RS11715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AREALGSMS7_RS11735	COG2217	Heavy metal translocating P-type atpase
AREALGSMS7_RS11785	COG2217	Heavy metal translocating P-type atpase
AREALGSMS7_RS11840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AREALGSMS7_RS11850	COG1428	Deoxynucleoside kinase
AREALGSMS7_RS11855	COG0616	signal peptide processing
AREALGSMS7_RS11895	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AREALGSMS7_RS11910	COG0415	Belongs to the DNA photolyase family
AREALGSMS7_RS11930	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AREALGSMS7_RS11940	COG0544	peptidyl-prolyl cis-trans isomerase activity
AREALGSMS7_RS11945	COG1950	PFAM Membrane protein of
AREALGSMS7_RS11950	COG0596	Alpha beta hydrolase
AREALGSMS7_RS11955	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AREALGSMS7_RS11965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AREALGSMS7_RS11975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AREALGSMS7_RS12010	COG2897	thiosulfate sulfurtransferase activity
AREALGSMS7_RS12035	COG3842	ATPase activity
AREALGSMS7_RS12045	COG0077	Prephenate dehydratase
AREALGSMS7_RS12045	COG1605	Chorismate mutase
AREALGSMS7_RS12050	COG0436	Aminotransferase
AREALGSMS7_RS12060	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AREALGSMS7_RS12075	COG1162	GTPase activity
AREALGSMS7_RS12080	COG1490	D-aminoacyl-tRNA deacylase activity
AREALGSMS7_RS12090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AREALGSMS7_RS12095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AREALGSMS7_RS12100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AREALGSMS7_RS12130	COG0358	DNA primase activity
AREALGSMS7_RS12140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AREALGSMS7_RS12160	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AREALGSMS7_RS12170	COG2001	Belongs to the MraZ family
AREALGSMS7_RS12175	COG0275	rRNA processing
AREALGSMS7_RS12190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AREALGSMS7_RS12195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AREALGSMS7_RS12200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AREALGSMS7_RS12205	COG0772	Belongs to the SEDS family
AREALGSMS7_RS12210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AREALGSMS7_RS12215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AREALGSMS7_RS12230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AREALGSMS7_RS12235	COG1610	YqeY-like protein
AREALGSMS7_RS12250	COG0475	glutathione-regulated potassium exporter activity
AREALGSMS7_RS12250	COG0589	response to stress
AREALGSMS7_RS12260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AREALGSMS7_RS12285	COG0469	pyruvate kinase activity
AREALGSMS7_RS12290	COG4677	pectinesterase activity
AREALGSMS7_RS12295	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS12300	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AREALGSMS7_RS12305	COG1609	Transcriptional regulator
AREALGSMS7_RS12310	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AREALGSMS7_RS12315	COG0492	ferredoxin-NADP+ reductase activity
AREALGSMS7_RS12320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AREALGSMS7_RS12325	COG0513	Belongs to the DEAD box helicase family
AREALGSMS7_RS12345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AREALGSMS7_RS12350	COG1185	polyribonucleotide nucleotidyltransferase activity
AREALGSMS7_RS12355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AREALGSMS7_RS12365	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AREALGSMS7_RS12370	COG0191	fructose-bisphosphate aldolase activity
AREALGSMS7_RS12390	COG2226	methyltransferase
AREALGSMS7_RS12395	COG0569	domain protein
AREALGSMS7_RS12400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AREALGSMS7_RS12405	COG0436	Aminotransferase
AREALGSMS7_RS12410	COG3239	Fatty acid desaturase
AREALGSMS7_RS12415	COG0357	Ribosomal RNA small subunit methyltransferase G
AREALGSMS7_RS12420	COG1012	belongs to the aldehyde dehydrogenase family
AREALGSMS7_RS12430	COG3385	transposase activity
AREALGSMS7_RS12455	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AREALGSMS7_RS12465	COG2198	Histidine kinase
AREALGSMS7_RS12465	COG0784	Response regulator, receiver
AREALGSMS7_RS12465	COG0643	Histidine kinase
AREALGSMS7_RS12470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AREALGSMS7_RS12565	COG0347	Belongs to the P(II) protein family
AREALGSMS7_RS12590	COG3781	membrane
AREALGSMS7_RS12610	COG2217	Heavy metal translocating P-type atpase
AREALGSMS7_RS12635	COG1321	iron dependent repressor
AREALGSMS7_RS12680	COG0582	viral genome integration into host DNA
AREALGSMS7_RS12710	COG1484	DNA-dependent DNA replication
AREALGSMS7_RS12715	COG4584	PFAM Integrase catalytic
AREALGSMS7_RS12725	COG3609	addiction module antidote protein, CC2985 family
AREALGSMS7_RS12760	COG3119	arylsulfatase activity
AREALGSMS7_RS12765	COG3119	arylsulfatase activity
AREALGSMS7_RS12770	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AREALGSMS7_RS12780	COG1217	gtp-binding protein TYPA
AREALGSMS7_RS12785	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS12810	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS12815	COG3275	phosphorelay sensor kinase activity
AREALGSMS7_RS12825	COG2884	Cell division ATP-binding protein ftsE
AREALGSMS7_RS12845	COG2885	chlorophyll binding
AREALGSMS7_RS12850	COG1278	Cold shock
AREALGSMS7_RS12855	COG4821	SIS domain
AREALGSMS7_RS12870	COG3119	arylsulfatase activity
AREALGSMS7_RS12885	COG0488	(ABC) transporter
AREALGSMS7_RS12905	COG0367	asparagine synthase
AREALGSMS7_RS12910	COG0187	DNA topoisomerase II activity
AREALGSMS7_RS12930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AREALGSMS7_RS12935	COG1119	ATPase activity
AREALGSMS7_RS12950	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AREALGSMS7_RS12955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AREALGSMS7_RS12960	COG0215	cysteine-tRNA ligase activity
AREALGSMS7_RS12965	COG0302	gtp cyclohydrolase
AREALGSMS7_RS13000	COG0442	prolyl-tRNA aminoacylation
AREALGSMS7_RS13015	COG0268	Binds directly to 16S ribosomal RNA
AREALGSMS7_RS13035	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AREALGSMS7_RS13040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AREALGSMS7_RS13050	COG0437	4 iron, 4 sulfur cluster binding
AREALGSMS7_RS13065	COG0243	molybdopterin cofactor binding
AREALGSMS7_RS13085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AREALGSMS7_RS13095	COG0105	UTP biosynthetic process
AREALGSMS7_RS13110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AREALGSMS7_RS13120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AREALGSMS7_RS13130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AREALGSMS7_RS13160	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS13175	COG0681	Belongs to the peptidase S26 family
AREALGSMS7_RS13180	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AREALGSMS7_RS13190	COG1475	DNA binding
AREALGSMS7_RS13195	COG1192	Involved in chromosome partitioning
AREALGSMS7_RS13200	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AREALGSMS7_RS13200	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AREALGSMS7_RS13205	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AREALGSMS7_RS13215	COG0572	uridine kinase
AREALGSMS7_RS13280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AREALGSMS7_RS13315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AREALGSMS7_RS13335	COG0842	Transport permease protein
AREALGSMS7_RS13340	COG1131	(ABC) transporter
AREALGSMS7_RS13360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AREALGSMS7_RS13365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AREALGSMS7_RS13380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AREALGSMS7_RS13385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AREALGSMS7_RS13390	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS13415	COG2814	Major facilitator Superfamily
AREALGSMS7_RS13430	COG0798	PFAM Bile acid sodium symporter
AREALGSMS7_RS13450	COG4106	trans-aconitate 2-methyltransferase activity
AREALGSMS7_RS13500	COG0653	protein targeting
AREALGSMS7_RS13510	COG2096	Adenosyltransferase
AREALGSMS7_RS13520	COG0488	(ABC) transporter
AREALGSMS7_RS13530	COG1183	phosphatidylcholine synthase activity
AREALGSMS7_RS13535	COG1137	ATPase activity
AREALGSMS7_RS13545	COG0805	protein transport
AREALGSMS7_RS13550	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS13550	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AREALGSMS7_RS13555	COG0514	ATP-dependent DNA helicase (RecQ)
AREALGSMS7_RS13560	COG1619	proteins homologs of microcin C7 resistance protein MccF
AREALGSMS7_RS13570	COG3153	acetyltransferase
AREALGSMS7_RS13570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AREALGSMS7_RS13575	COG1187	pseudouridine synthase activity
AREALGSMS7_RS13595	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AREALGSMS7_RS13600	COG0076	glutamate decarboxylase activity
AREALGSMS7_RS13615	COG0519	Catalyzes the synthesis of GMP from XMP
AREALGSMS7_RS13615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AREALGSMS7_RS13640	COG3530	Putative quorum-sensing-regulated virulence factor
AREALGSMS7_RS13645	COG0504	CTP synthase activity
AREALGSMS7_RS13650	COG0706	membrane insertase activity
AREALGSMS7_RS13655	COG0482	sulfurtransferase activity
AREALGSMS7_RS13660	COG1404	Belongs to the peptidase S8 family
AREALGSMS7_RS13690	COG0714	Associated with various cellular activities
AREALGSMS7_RS13725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AREALGSMS7_RS13730	COG0494	nUDIX hydrolase
AREALGSMS7_RS13755	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS13760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AREALGSMS7_RS13770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AREALGSMS7_RS13775	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AREALGSMS7_RS13785	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AREALGSMS7_RS13800	COG2270	Major facilitator Superfamily
AREALGSMS7_RS13825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AREALGSMS7_RS13830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AREALGSMS7_RS13850	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AREALGSMS7_RS13855	COG0540	Belongs to the ATCase OTCase family
AREALGSMS7_RS13865	COG1234	tRNA 3'-trailer cleavage
AREALGSMS7_RS13870	COG0259	pyridoxamine-phosphate oxidase activity
AREALGSMS7_RS13880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AREALGSMS7_RS13920	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AREALGSMS7_RS13945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AREALGSMS7_RS13970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AREALGSMS7_RS13980	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AREALGSMS7_RS13985	COG1011	Hydrolase
AREALGSMS7_RS13990	COG1454	alcohol dehydrogenase
AREALGSMS7_RS14005	COG0217	transcriptional regulatory protein
AREALGSMS7_RS14010	COG2154	pterin-4-alpha-carbinolamine dehydratase
AREALGSMS7_RS14020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AREALGSMS7_RS14025	COG0006	proline dipeptidase activity
AREALGSMS7_RS14030	COG0438	transferase activity, transferring glycosyl groups
AREALGSMS7_RS14035	COG0562	UDP-galactopyranose mutase
AREALGSMS7_RS14040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AREALGSMS7_RS14045	COG0083	homoserine kinase activity
AREALGSMS7_RS14050	COG0527	aspartate kinase activity
AREALGSMS7_RS14050	COG0460	homoserine dehydrogenase
AREALGSMS7_RS14055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AREALGSMS7_RS14065	COG0542	response to heat
AREALGSMS7_RS14085	COG0183	Belongs to the thiolase family
AREALGSMS7_RS14110	COG3940	Belongs to the glycosyl hydrolase 43 family
AREALGSMS7_RS14135	COG0386	Belongs to the glutathione peroxidase family
AREALGSMS7_RS14140	COG0300	oxidoreductase activity
AREALGSMS7_RS14150	COG0302	gtp cyclohydrolase
AREALGSMS7_RS14165	COG0702	epimerase
AREALGSMS7_RS14190	COG1289	transmembrane transporter activity
AREALGSMS7_RS14195	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AREALGSMS7_RS14235	COG3119	arylsulfatase activity
AREALGSMS7_RS14250	COG1024	Enoyl-CoA hydratase
AREALGSMS7_RS14255	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS14260	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS14275	COG0783	Belongs to the Dps family
AREALGSMS7_RS14290	COG4251	negative regulation of phosphorylation
AREALGSMS7_RS14295	COG2201	protein-glutamate methylesterase activity
AREALGSMS7_RS14320	COG0668	transmembrane transport
AREALGSMS7_RS14330	COG1012	belongs to the aldehyde dehydrogenase family
AREALGSMS7_RS14375	COG1132	(ABC) transporter
AREALGSMS7_RS14385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AREALGSMS7_RS14400	COG0149	triose-phosphate isomerase activity
AREALGSMS7_RS14405	COG2264	protein methyltransferase activity
AREALGSMS7_RS14420	COG2391	methyltransferase activity
AREALGSMS7_RS14450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AREALGSMS7_RS14455	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AREALGSMS7_RS14465	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AREALGSMS7_RS14485	COG1629	transport
AREALGSMS7_RS14520	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS14610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AREALGSMS7_RS14620	COG4771	TonB-dependent receptor
AREALGSMS7_RS14630	COG0784	Response regulator, receiver
AREALGSMS7_RS14655	COG3237	CsbD-like
AREALGSMS7_RS14670	COG2354	Protein conserved in bacteria
AREALGSMS7_RS14715	COG1609	Transcriptional regulator
AREALGSMS7_RS14725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AREALGSMS7_RS14780	COG3292	Two component regulator propeller
AREALGSMS7_RS14780	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS14780	COG2205	protein histidine kinase activity
AREALGSMS7_RS14815	COG1629	transport
AREALGSMS7_RS14820	COG0702	epimerase
AREALGSMS7_RS14825	COG3119	arylsulfatase activity
AREALGSMS7_RS14830	COG3119	arylsulfatase activity
AREALGSMS7_RS14880	COG2188	Transcriptional regulator
AREALGSMS7_RS14895	COG4771	TonB-dependent receptor
AREALGSMS7_RS14900	COG0702	epimerase
AREALGSMS7_RS14905	COG3119	arylsulfatase activity
AREALGSMS7_RS14910	COG3940	Belongs to the glycosyl hydrolase 43 family
AREALGSMS7_RS14915	COG3254	rhamnose metabolic process
AREALGSMS7_RS14920	COG3940	Belongs to the glycosyl hydrolase 43 family
AREALGSMS7_RS14925	COG3940	Belongs to the glycosyl hydrolase 43 family
AREALGSMS7_RS14960	COG0069	glutamate synthase activity
AREALGSMS7_RS14970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AREALGSMS7_RS14975	COG0783	Belongs to the Dps family
AREALGSMS7_RS14980	COG0668	transmembrane transport
AREALGSMS7_RS14990	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS14995	COG1366	Belongs to the anti-sigma-factor antagonist family
AREALGSMS7_RS14995	COG2202	Pas domain
AREALGSMS7_RS15040	COG2807	transmembrane transport
AREALGSMS7_RS15055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AREALGSMS7_RS15085	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS15085	COG3292	Two component regulator propeller
AREALGSMS7_RS15085	COG2205	protein histidine kinase activity
AREALGSMS7_RS15090	COG4771	TonB-dependent receptor
AREALGSMS7_RS15125	COG1929	Belongs to the glycerate kinase type-1 family
AREALGSMS7_RS15140	COG5564	TIM-barrel signal transduction protein
AREALGSMS7_RS15180	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS15180	COG3292	Two component regulator propeller
AREALGSMS7_RS15180	COG2205	protein histidine kinase activity
AREALGSMS7_RS15185	COG2814	Major facilitator Superfamily
AREALGSMS7_RS15190	COG1621	beta-fructofuranosidase activity
AREALGSMS7_RS15195	COG4771	TonB-dependent receptor
AREALGSMS7_RS15230	COG1401	restriction endodeoxyribonuclease activity
AREALGSMS7_RS15240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AREALGSMS7_RS15245	COG0732	type I restriction modification DNA specificity domain
AREALGSMS7_RS15280	COG1858	cytochrome C peroxidase
AREALGSMS7_RS15285	COG3250	beta-galactosidase activity
AREALGSMS7_RS15290	COG3119	arylsulfatase activity
AREALGSMS7_RS15300	COG3119	arylsulfatase activity
AREALGSMS7_RS15315	COG3119	arylsulfatase activity
AREALGSMS7_RS15315	COG3408	Glycogen debranching enzyme
AREALGSMS7_RS15335	COG0702	epimerase
AREALGSMS7_RS15340	COG4771	TonB-dependent receptor
AREALGSMS7_RS15355	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS15355	COG3347	Dehydrogenase
AREALGSMS7_RS15360	COG4952	isomerase
AREALGSMS7_RS15365	COG1070	Carbohydrate kinase
AREALGSMS7_RS15385	COG3119	arylsulfatase activity
AREALGSMS7_RS15390	COG3254	rhamnose metabolic process
AREALGSMS7_RS15395	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AREALGSMS7_RS15400	COG0667	Aldo Keto reductase
AREALGSMS7_RS15405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AREALGSMS7_RS15410	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AREALGSMS7_RS15420	COG1288	antiporter activity
AREALGSMS7_RS15445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AREALGSMS7_RS15450	COG1312	Catalyzes the dehydration of D-mannonate
AREALGSMS7_RS15460	COG3046	protein related to deoxyribodipyrimidine photolyase
AREALGSMS7_RS15470	COG0415	Belongs to the DNA photolyase family
AREALGSMS7_RS15490	COG5002	protein histidine kinase activity
AREALGSMS7_RS15515	COG4585	Histidine kinase
AREALGSMS7_RS15530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AREALGSMS7_RS15545	COG2076	Multidrug Resistance protein
AREALGSMS7_RS15565	COG0322	excinuclease ABC activity
AREALGSMS7_RS15580	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS15595	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS15610	COG1917	Cupin 2, conserved barrel domain protein
AREALGSMS7_RS15610	COG2207	Transcriptional regulator
AREALGSMS7_RS15640	COG0300	oxidoreductase activity
AREALGSMS7_RS15645	COG0604	alcohol dehydrogenase
AREALGSMS7_RS15645	COG3321	synthase
AREALGSMS7_RS15655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AREALGSMS7_RS15660	COG1012	belongs to the aldehyde dehydrogenase family
AREALGSMS7_RS15670	COG1858	cytochrome C peroxidase
AREALGSMS7_RS15680	COG0587	DNA-directed DNA polymerase activity
AREALGSMS7_RS15690	COG0860	N-Acetylmuramoyl-L-alanine amidase
AREALGSMS7_RS15700	COG2181	nitrate reductase activity
AREALGSMS7_RS15700	COG0247	lactate metabolic process
AREALGSMS7_RS15705	COG0247	lactate metabolic process
AREALGSMS7_RS15705	COG2181	nitrate reductase activity
AREALGSMS7_RS15715	COG1472	Belongs to the glycosyl hydrolase 3 family
AREALGSMS7_RS15720	COG0438	transferase activity, transferring glycosyl groups
AREALGSMS7_RS15730	COG2885	chlorophyll binding
AREALGSMS7_RS15760	COG2963	transposase activity
AREALGSMS7_RS15765	COG2801	Transposase and inactivated derivatives
AREALGSMS7_RS15785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AREALGSMS7_RS15790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AREALGSMS7_RS15795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AREALGSMS7_RS15805	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS15815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AREALGSMS7_RS15830	COG1216	Glycosyl transferase, family 2
AREALGSMS7_RS15835	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS15845	COG0656	L-ascorbic acid biosynthetic process
AREALGSMS7_RS15855	COG3206	protein involved in exopolysaccharide biosynthesis
AREALGSMS7_RS15855	COG0489	protein tyrosine kinase activity
AREALGSMS7_RS15875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AREALGSMS7_RS15885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AREALGSMS7_RS15905	COG0438	transferase activity, transferring glycosyl groups
AREALGSMS7_RS15910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AREALGSMS7_RS15915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AREALGSMS7_RS15925	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AREALGSMS7_RS15930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AREALGSMS7_RS15940	COG1090	epimerase
AREALGSMS7_RS15950	COG2801	Transposase and inactivated derivatives
AREALGSMS7_RS15955	COG2963	transposase activity
AREALGSMS7_RS15980	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AREALGSMS7_RS16015	COG2824	Alkylphosphonate utilization operon protein PhnA
AREALGSMS7_RS16025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AREALGSMS7_RS16025	COG2010	Cytochrome c
AREALGSMS7_RS16045	COG1595	DNA-templated transcription, initiation
AREALGSMS7_RS16055	COG4771	TonB-dependent receptor
AREALGSMS7_RS16065	COG3119	arylsulfatase activity
AREALGSMS7_RS16075	COG3119	arylsulfatase activity
AREALGSMS7_RS16085	COG1966	Carbon starvation protein
AREALGSMS7_RS16115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AREALGSMS7_RS16125	COG2267	carboxylic ester hydrolase activity
AREALGSMS7_RS16130	COG3177	Filamentation induced by cAMP protein fic
AREALGSMS7_RS16135	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AREALGSMS7_RS16150	COG0592	DNA-directed DNA polymerase activity
AREALGSMS7_RS16175	COG1702	phosphate starvation-inducible protein PhoH
AREALGSMS7_RS16180	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AREALGSMS7_RS16185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AREALGSMS7_RS16200	COG3273	potassium ion transport
AREALGSMS7_RS16200	COG0471	metal ion transport
AREALGSMS7_RS16210	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AREALGSMS7_RS16215	COG2195	Cleaves the N-terminal amino acid of tripeptides
AREALGSMS7_RS16225	COG0167	dihydroorotate dehydrogenase activity
AREALGSMS7_RS16250	COG1730	sister chromatid segregation
AREALGSMS7_RS16265	COG0516	GMP reductase activity
AREALGSMS7_RS16265	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS16275	COG0019	diaminopimelate decarboxylase activity
AREALGSMS7_RS16285	COG0045	succinate-CoA ligase (ADP-forming) activity
AREALGSMS7_RS16305	COG0556	nucleotide-excision repair
AREALGSMS7_RS16315	COG1131	(ABC) transporter
AREALGSMS7_RS16335	COG1612	heme a metabolic process
AREALGSMS7_RS16340	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS16340	COG0617	tRNA 3'-terminal CCA addition
AREALGSMS7_RS16340	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AREALGSMS7_RS16345	COG0009	L-threonylcarbamoyladenylate synthase
AREALGSMS7_RS16380	COG2171	N-acyltransferase activity
AREALGSMS7_RS16385	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AREALGSMS7_RS16390	COG0242	peptide deformylase activity
AREALGSMS7_RS16415	COG3275	phosphorelay sensor kinase activity
AREALGSMS7_RS16465	COG0823	Involved in the tonB-independent uptake of proteins
AREALGSMS7_RS16470	COG3956	TIGRFAM MazG family protein
AREALGSMS7_RS16480	COG0534	Mate efflux family protein
AREALGSMS7_RS16490	COG0671	phosphoesterase, PA-phosphatase related
AREALGSMS7_RS16505	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AREALGSMS7_RS16505	COG3952	Lipid A Biosynthesis
AREALGSMS7_RS16510	COG0463	Glycosyl transferase, family 2
AREALGSMS7_RS16525	COG2017	converts alpha-aldose to the beta-anomer
AREALGSMS7_RS16530	COG1595	DNA-templated transcription, initiation
AREALGSMS7_RS16545	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS16555	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AREALGSMS7_RS16575	COG4191	Histidine kinase
AREALGSMS7_RS16580	COG2201	protein-glutamate methylesterase activity
AREALGSMS7_RS16600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AREALGSMS7_RS16605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AREALGSMS7_RS16625	COG1472	Belongs to the glycosyl hydrolase 3 family
AREALGSMS7_RS16630	COG2211	Major facilitator Superfamily
AREALGSMS7_RS16635	COG1649	PFAM Uncharacterised BCR, COG1649
AREALGSMS7_RS16645	COG1629	transport
AREALGSMS7_RS16645	COG4206	TonB-dependent receptor
AREALGSMS7_RS16650	COG1349	DNA-binding transcription factor activity
AREALGSMS7_RS16655	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AREALGSMS7_RS16665	COG2133	pyrroloquinoline quinone binding
AREALGSMS7_RS16715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AREALGSMS7_RS16725	COG1538	Outer membrane efflux protein
AREALGSMS7_RS16760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AREALGSMS7_RS16775	COG3384	dioxygenase
AREALGSMS7_RS16795	COG0702	epimerase
AREALGSMS7_RS16800	COG1733	regulation of RNA biosynthetic process
AREALGSMS7_RS16810	COG0667	Aldo Keto reductase
AREALGSMS7_RS16830	COG4771	TonB-dependent receptor
AREALGSMS7_RS16855	COG2207	Transcriptional regulator
AREALGSMS7_RS16855	COG1609	Transcriptional regulator
AREALGSMS7_RS16890	COG0551	DNA topoisomerase type I activity
AREALGSMS7_RS16890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AREALGSMS7_RS16950	COG0464	growth
AREALGSMS7_RS17050	COG0587	DNA-directed DNA polymerase activity
AREALGSMS7_RS17055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AREALGSMS7_RS17105	COG0629	single-stranded DNA binding
AREALGSMS7_RS17125	COG4206	TonB-dependent receptor
AREALGSMS7_RS17125	COG1629	transport
AREALGSMS7_RS17130	COG1522	sequence-specific DNA binding
AREALGSMS7_RS17165	COG2249	NAD(P)H dehydrogenase (quinone) activity
AREALGSMS7_RS17170	COG0668	transmembrane transport
AREALGSMS7_RS17190	COG2249	NAD(P)H dehydrogenase (quinone) activity
AREALGSMS7_RS17205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AREALGSMS7_RS17210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AREALGSMS7_RS17225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AREALGSMS7_RS17255	COG0589	response to stress
AREALGSMS7_RS17265	COG0589	response to stress
AREALGSMS7_RS17275	COG0589	response to stress
AREALGSMS7_RS17290	COG0589	response to stress
AREALGSMS7_RS17300	COG5002	protein histidine kinase activity
AREALGSMS7_RS17310	COG0589	response to stress
AREALGSMS7_RS17320	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS17330	COG1994	Peptidase M50
AREALGSMS7_RS17330	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS17340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AREALGSMS7_RS17345	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AREALGSMS7_RS17355	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AREALGSMS7_RS17365	COG2202	Pas domain
AREALGSMS7_RS17365	COG1366	Belongs to the anti-sigma-factor antagonist family
AREALGSMS7_RS17370	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS17410	COG0708	Exodeoxyribonuclease III
AREALGSMS7_RS17430	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AREALGSMS7_RS17435	COG0857	belongs to the CobB CobQ family
AREALGSMS7_RS17435	COG0280	phosphate acetyltransferase
AREALGSMS7_RS17440	COG0589	response to stress
AREALGSMS7_RS17445	COG0837	glucose binding
AREALGSMS7_RS17450	COG1105	Belongs to the carbohydrate kinase PfkB family
AREALGSMS7_RS17455	COG0574	Belongs to the PEP-utilizing enzyme family
AREALGSMS7_RS17455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AREALGSMS7_RS17475	COG1136	(ABC) transporter
AREALGSMS7_RS17475	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS17480	COG1136	(ABC) transporter
AREALGSMS7_RS17505	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS17525	COG0702	epimerase
AREALGSMS7_RS17530	COG1629	transport
AREALGSMS7_RS17535	COG1629	transport
AREALGSMS7_RS17535	COG4206	TonB-dependent receptor
AREALGSMS7_RS17540	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS17550	COG3292	Two component regulator propeller
AREALGSMS7_RS17550	COG2205	protein histidine kinase activity
AREALGSMS7_RS17550	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS17570	COG2234	aminopeptidase activity
AREALGSMS7_RS17570	COG4935	Belongs to the peptidase S8 family
AREALGSMS7_RS17575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AREALGSMS7_RS17580	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AREALGSMS7_RS17585	COG1085	galactose-1-phosphate uridylyltransferase
AREALGSMS7_RS17595	COG0789	Transcriptional regulator
AREALGSMS7_RS17600	COG0484	heat shock protein binding
AREALGSMS7_RS17605	COG0589	response to stress
AREALGSMS7_RS17610	COG0492	ferredoxin-NADP+ reductase activity
AREALGSMS7_RS17620	COG4206	TonB-dependent receptor
AREALGSMS7_RS17620	COG1629	transport
AREALGSMS7_RS17630	COG0156	8-amino-7-oxononanoate synthase activity
AREALGSMS7_RS17635	COG4948	Mandelate Racemase Muconate Lactonizing
AREALGSMS7_RS17680	COG0494	nUDIX hydrolase
AREALGSMS7_RS17685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AREALGSMS7_RS17715	COG1136	(ABC) transporter
AREALGSMS7_RS17715	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS17725	COG0783	Belongs to the Dps family
AREALGSMS7_RS17805	COG2814	Major facilitator Superfamily
AREALGSMS7_RS17820	COG0778	Nitroreductase
AREALGSMS7_RS17870	COG0475	glutathione-regulated potassium exporter activity
AREALGSMS7_RS17875	COG0531	amino acid
AREALGSMS7_RS17940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AREALGSMS7_RS17960	COG0604	alcohol dehydrogenase
AREALGSMS7_RS18075	COG1484	DNA-dependent DNA replication
AREALGSMS7_RS18140	COG3549	Plasmid maintenance system killer
AREALGSMS7_RS18165	COG4221	oxidoreductase activity
AREALGSMS7_RS18175	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS18225	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS18230	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AREALGSMS7_RS18240	COG4771	TonB-dependent receptor
AREALGSMS7_RS18245	COG0702	epimerase
AREALGSMS7_RS18290	COG1917	Cupin 2, conserved barrel domain protein
AREALGSMS7_RS18290	COG2169	Transcriptional regulator
AREALGSMS7_RS18315	COG0659	secondary active sulfate transmembrane transporter activity
AREALGSMS7_RS18330	COG0598	Magnesium transport protein CorA
AREALGSMS7_RS18335	COG3264	Mechanosensitive ion channel
AREALGSMS7_RS18335	COG1196	nuclear chromosome segregation
AREALGSMS7_RS18350	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS18370	COG3119	arylsulfatase activity
AREALGSMS7_RS18415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AREALGSMS7_RS18445	COG5434	Belongs to the glycosyl hydrolase 28 family
AREALGSMS7_RS18455	COG1073	alpha beta
AREALGSMS7_RS18470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AREALGSMS7_RS18475	COG1522	sequence-specific DNA binding
AREALGSMS7_RS18485	COG0156	8-amino-7-oxononanoate synthase activity
AREALGSMS7_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS18540	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS18545	COG3458	cephalosporin-C deacetylase activity
AREALGSMS7_RS18555	COG5002	protein histidine kinase activity
AREALGSMS7_RS18555	COG0784	Response regulator, receiver
AREALGSMS7_RS18565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AREALGSMS7_RS18580	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AREALGSMS7_RS18585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AREALGSMS7_RS18655	COG2205	protein histidine kinase activity
AREALGSMS7_RS18655	COG0784	Response regulator, receiver
AREALGSMS7_RS18665	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS18730	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS18740	COG2211	Major facilitator Superfamily
AREALGSMS7_RS18765	COG0300	oxidoreductase activity
AREALGSMS7_RS18775	COG0129	dihydroxy-acid dehydratase activity
AREALGSMS7_RS18800	COG1678	Uncharacterized ACR, COG1678
AREALGSMS7_RS18810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AREALGSMS7_RS18815	COG0514	ATP-dependent DNA helicase (RecQ)
AREALGSMS7_RS18835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AREALGSMS7_RS18850	COG1846	Transcriptional regulator
AREALGSMS7_RS18850	COG0456	acetyltransferase
AREALGSMS7_RS18905	COG0457	Tetratricopeptide repeat
AREALGSMS7_RS18920	COG4771	TonB-dependent receptor
AREALGSMS7_RS18925	COG1609	Transcriptional regulator
AREALGSMS7_RS18950	COG0424	maF-like protein
AREALGSMS7_RS18965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AREALGSMS7_RS18965	COG1333	cytochrome c biogenesis protein
AREALGSMS7_RS18970	COG0534	Mate efflux family protein
AREALGSMS7_RS18975	COG0626	cystathionine gamma-synthase activity
AREALGSMS7_RS18980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AREALGSMS7_RS18985	COG2205	protein histidine kinase activity
AREALGSMS7_RS18985	COG2202	Pas domain
AREALGSMS7_RS19000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AREALGSMS7_RS19030	COG0069	glutamate synthase activity
AREALGSMS7_RS19035	COG1473	amidohydrolase
AREALGSMS7_RS19050	COG0009	L-threonylcarbamoyladenylate synthase
AREALGSMS7_RS19090	COG1611	Belongs to the LOG family
AREALGSMS7_RS19125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AREALGSMS7_RS19130	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS19135	COG4948	Mandelate Racemase Muconate Lactonizing
AREALGSMS7_RS19140	COG1266	CAAX protease self-immunity
AREALGSMS7_RS19155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AREALGSMS7_RS19160	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS19170	COG0488	(ABC) transporter
AREALGSMS7_RS19195	COG3011	Protein conserved in bacteria
AREALGSMS7_RS19200	COG1193	negative regulation of DNA recombination
AREALGSMS7_RS19215	COG1132	(ABC) transporter
AREALGSMS7_RS19220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AREALGSMS7_RS19225	COG0463	Glycosyl transferase, family 2
AREALGSMS7_RS19235	COG0254	rRNA binding
AREALGSMS7_RS19245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AREALGSMS7_RS19265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AREALGSMS7_RS19280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AREALGSMS7_RS19285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AREALGSMS7_RS19290	COG2936	dipeptidyl-peptidase activity
AREALGSMS7_RS19300	COG4181	ATPase activity
AREALGSMS7_RS19305	COG1136	(ABC) transporter
AREALGSMS7_RS19305	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS19330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AREALGSMS7_RS19340	COG1929	Belongs to the glycerate kinase type-1 family
AREALGSMS7_RS19345	COG5564	TIM-barrel signal transduction protein
AREALGSMS7_RS19360	COG3263	regulation of cellular component size
AREALGSMS7_RS19375	COG4771	TonB-dependent receptor
AREALGSMS7_RS19395	COG4585	Histidine kinase
AREALGSMS7_RS19410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AREALGSMS7_RS19415	COG1648	precorrin-2 dehydrogenase activity
AREALGSMS7_RS19415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AREALGSMS7_RS19420	COG2223	nitrite transmembrane transporter activity
AREALGSMS7_RS19435	COG0243	molybdopterin cofactor binding
AREALGSMS7_RS19445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AREALGSMS7_RS19460	COG0154	amidase activity
AREALGSMS7_RS19475	COG2378	regulation of single-species biofilm formation
AREALGSMS7_RS19520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AREALGSMS7_RS19525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AREALGSMS7_RS19525	COG0574	Belongs to the PEP-utilizing enzyme family
AREALGSMS7_RS19530	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS19585	COG0640	Transcriptional regulator
AREALGSMS7_RS19605	COG2207	Transcriptional regulator
AREALGSMS7_RS19625	COG4771	TonB-dependent receptor
AREALGSMS7_RS19630	COG2814	Major facilitator Superfamily
AREALGSMS7_RS19640	COG4251	negative regulation of phosphorylation
AREALGSMS7_RS19645	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS19650	COG0784	Response regulator, receiver
AREALGSMS7_RS19655	COG4251	negative regulation of phosphorylation
AREALGSMS7_RS19660	COG0784	Response regulator, receiver
AREALGSMS7_RS19665	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AREALGSMS7_RS19665	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AREALGSMS7_RS19685	COG4251	negative regulation of phosphorylation
AREALGSMS7_RS19690	COG4251	negative regulation of phosphorylation
AREALGSMS7_RS19735	COG4565	transcriptional regulatory protein
AREALGSMS7_RS19765	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AREALGSMS7_RS19795	COG2003	Belongs to the UPF0758 family
AREALGSMS7_RS19800	COG0629	single-stranded DNA binding
AREALGSMS7_RS19850	COG0860	N-Acetylmuramoyl-L-alanine amidase
AREALGSMS7_RS19875	COG3852	Histidine kinase
AREALGSMS7_RS19880	COG2204	response regulator
AREALGSMS7_RS19895	COG1136	(ABC) transporter
AREALGSMS7_RS19900	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS19905	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS19910	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS19910	COG1136	(ABC) transporter
AREALGSMS7_RS19915	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS19930	COG2186	Transcriptional regulator
AREALGSMS7_RS19935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AREALGSMS7_RS19940	COG4771	TonB-dependent receptor
AREALGSMS7_RS19965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AREALGSMS7_RS19970	COG0583	DNA-binding transcription factor activity
AREALGSMS7_RS19975	COG0450	alkyl hydroperoxide reductase
AREALGSMS7_RS19980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AREALGSMS7_RS19985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AREALGSMS7_RS19990	COG2226	methyltransferase
AREALGSMS7_RS19995	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AREALGSMS7_RS20010	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS20020	COG1252	NADH dehydrogenase
AREALGSMS7_RS20035	COG2205	protein histidine kinase activity
AREALGSMS7_RS20075	COG2169	Transcriptional regulator
AREALGSMS7_RS20115	COG0038	chloride channel
AREALGSMS7_RS20140	COG0732	type I restriction modification DNA specificity domain
AREALGSMS7_RS20160	COG1629	transport
AREALGSMS7_RS20170	COG0612	Peptidase, M16
AREALGSMS7_RS20185	COG2207	Transcriptional regulator
AREALGSMS7_RS20185	COG1609	Transcriptional regulator
AREALGSMS7_RS20230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AREALGSMS7_RS20245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AREALGSMS7_RS20245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AREALGSMS7_RS20260	COG1674	ftsk spoiiie
AREALGSMS7_RS20280	COG3118	belongs to the thioredoxin family
AREALGSMS7_RS20285	COG0450	alkyl hydroperoxide reductase
AREALGSMS7_RS20290	COG1757	Na H antiporter
AREALGSMS7_RS20300	COG1522	sequence-specific DNA binding
AREALGSMS7_RS20305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AREALGSMS7_RS20320	COG0431	NADPH-dependent FMN reductase
AREALGSMS7_RS20335	COG0037	tRNA processing
AREALGSMS7_RS20380	COG2957	Belongs to the agmatine deiminase family
AREALGSMS7_RS20400	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS20420	COG1914	H( )-stimulated, divalent metal cation uptake system
AREALGSMS7_RS20425	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AREALGSMS7_RS20430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AREALGSMS7_RS20440	COG0129	dihydroxy-acid dehydratase activity
AREALGSMS7_RS20445	COG0028	Belongs to the TPP enzyme family
AREALGSMS7_RS20450	COG0440	acetolactate synthase activity
AREALGSMS7_RS20455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AREALGSMS7_RS20460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AREALGSMS7_RS20465	COG1012	belongs to the aldehyde dehydrogenase family
AREALGSMS7_RS20470	COG2205	protein histidine kinase activity
AREALGSMS7_RS20470	COG0784	Response regulator, receiver
AREALGSMS7_RS20480	COG2814	Major facilitator Superfamily
AREALGSMS7_RS20500	COG0066	3-isopropylmalate dehydratase activity
AREALGSMS7_RS20505	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AREALGSMS7_RS20510	COG2234	aminopeptidase activity
AREALGSMS7_RS20515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AREALGSMS7_RS20525	COG3938	Belongs to the proline racemase family
AREALGSMS7_RS20530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AREALGSMS7_RS20550	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS20590	COG1169	isochorismate synthase
AREALGSMS7_RS20595	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AREALGSMS7_RS20605	COG2996	Protein conserved in bacteria
AREALGSMS7_RS20615	COG1575	Belongs to the MenA family. Type 1 subfamily
AREALGSMS7_RS20620	COG0784	Response regulator, receiver
AREALGSMS7_RS20625	COG2201	protein-glutamate methylesterase activity
AREALGSMS7_RS20700	COG2234	aminopeptidase activity
AREALGSMS7_RS20715	COG3387	PFAM Glycoside hydrolase 15-related
AREALGSMS7_RS20735	COG0302	gtp cyclohydrolase
AREALGSMS7_RS20785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AREALGSMS7_RS20790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AREALGSMS7_RS20800	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AREALGSMS7_RS20805	COG1629	transport
AREALGSMS7_RS20810	COG0012	GTP binding
AREALGSMS7_RS20830	COG0861	Integral membrane protein TerC family
AREALGSMS7_RS20850	COG1522	sequence-specific DNA binding
AREALGSMS7_RS20865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AREALGSMS7_RS20900	COG2204	response regulator
AREALGSMS7_RS20905	COG1078	dGTPase activity
AREALGSMS7_RS20910	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AREALGSMS7_RS20915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AREALGSMS7_RS20915	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AREALGSMS7_RS20920	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AREALGSMS7_RS20925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AREALGSMS7_RS20930	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AREALGSMS7_RS20935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AREALGSMS7_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS20955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AREALGSMS7_RS20960	COG0456	acetyltransferase
AREALGSMS7_RS20965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AREALGSMS7_RS20970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AREALGSMS7_RS20975	COG0131	Imidazoleglycerol-phosphate dehydratase
AREALGSMS7_RS20985	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AREALGSMS7_RS20990	COG0107	imidazoleglycerol-phosphate synthase activity
AREALGSMS7_RS20995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AREALGSMS7_RS20995	COG0140	phosphoribosyl-ATP diphosphatase activity
AREALGSMS7_RS21000	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS21035	COG0598	Magnesium transport protein CorA
AREALGSMS7_RS21045	COG1045	serine acetyltransferase
AREALGSMS7_RS21060	COG1607	acyl-coa hydrolase
AREALGSMS7_RS21080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AREALGSMS7_RS21090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AREALGSMS7_RS21110	COG1629	transport
AREALGSMS7_RS21140	COG1785	Belongs to the alkaline phosphatase family
AREALGSMS7_RS21145	COG1360	Flagellar Motor Protein
AREALGSMS7_RS21155	COG0363	glucosamine-6-phosphate deaminase activity
AREALGSMS7_RS21180	COG0315	cyclic pyranopterin monophosphate synthase activity
AREALGSMS7_RS21180	COG0746	molybdenum cofactor guanylyltransferase activity
AREALGSMS7_RS21185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AREALGSMS7_RS21195	COG0303	'Molybdopterin
AREALGSMS7_RS21200	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AREALGSMS7_RS21230	COG4206	TonB-dependent receptor
AREALGSMS7_RS21235	COG0514	ATP-dependent DNA helicase (RecQ)
AREALGSMS7_RS21245	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AREALGSMS7_RS21305	COG0577	efflux transmembrane transporter activity
AREALGSMS7_RS21305	COG1136	(ABC) transporter
AREALGSMS7_RS21310	COG1136	(ABC) transporter
AREALGSMS7_RS21350	COG0446	pyridine nucleotide-disulphide oxidoreductase
AREALGSMS7_RS21350	COG1902	pentaerythritol trinitrate reductase activity
AREALGSMS7_RS21365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AREALGSMS7_RS21385	COG3590	peptidase
AREALGSMS7_RS21420	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS21430	COG0604	alcohol dehydrogenase
AREALGSMS7_RS21465	COG2207	Transcriptional regulator
AREALGSMS7_RS21475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AREALGSMS7_RS21490	COG1309	transcriptional regulator
AREALGSMS7_RS21500	COG0484	heat shock protein binding
AREALGSMS7_RS21505	COG1278	Cold shock
AREALGSMS7_RS21515	COG1028	Short-chain dehydrogenase reductase Sdr
AREALGSMS7_RS21520	COG0513	Belongs to the DEAD box helicase family
AREALGSMS7_RS21545	COG1309	transcriptional regulator
AREALGSMS7_RS21550	COG2130	NADP-dependent
AREALGSMS7_RS21570	COG0339	signal peptide processing
AREALGSMS7_RS21580	COG2205	protein histidine kinase activity
AREALGSMS7_RS21580	COG0745	RESPONSE REGULATOR receiver
AREALGSMS7_RS21580	COG3292	Two component regulator propeller
AREALGSMS7_RS21595	COG0277	FAD linked oxidase domain protein
AREALGSMS7_RS21605	COG2207	Transcriptional regulator
AREALGSMS7_RS21605	COG0662	Cupin 2, conserved barrel domain protein
AREALGSMS7_RS21615	COG1321	iron dependent repressor
AREALGSMS7_RS21615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AREALGSMS7_RS21645	COG1187	pseudouridine synthase activity
AREALGSMS7_RS21650	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AREALGSMS7_RS21665	COG1047	Peptidyl-prolyl cis-trans
AREALGSMS7_RS21675	COG1278	Cold shock
AREALGSMS7_RS21680	COG1629	transport
AREALGSMS7_RS21685	COG1764	response to oxidative stress
AREALGSMS7_RS21690	COG0697	spore germination
AREALGSMS7_RS21700	COG1704	LemA family
AREALGSMS7_RS21710	COG3344	reverse transcriptase
AREALGSMS7_RS21720	COG1741	Belongs to the pirin family
AREALGSMS7_RS21725	COG1858	cytochrome C peroxidase
AREALGSMS7_RS21740	COG4628	conserved protein (DUF2132)
AREALGSMS7_RS21745	COG0513	Belongs to the DEAD box helicase family
AREALGSMS7_RS21770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AREALGSMS7_RS21775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AREALGSMS7_RS21795	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AREALGSMS7_RS21800	COG2885	chlorophyll binding
AREALGSMS7_RS21815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AREALGSMS7_RS21820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AREALGSMS7_RS21825	COG2204	response regulator
AREALGSMS7_RS21830	COG3852	Histidine kinase
AREALGSMS7_RS21835	COG0022	dehydrogenase e1 component
AREALGSMS7_RS21850	COG0023	Translation Initiation Factor
AREALGSMS7_RS21870	COG2201	protein-glutamate methylesterase activity
AREALGSMS7_RS21875	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AREALGSMS7_RS21880	COG1595	DNA-templated transcription, initiation
AREALGSMS7_RS21900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AREALGSMS7_RS21900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AREALGSMS7_RS21910	COG1960	acyl-CoA dehydrogenase activity
AREALGSMS7_RS21935	COG1022	Amp-dependent synthetase and ligase
AREALGSMS7_RS21940	COG1846	Transcriptional regulator
AREALGSMS7_RS21945	COG1024	Enoyl-CoA hydratase
AREALGSMS7_RS21945	COG1250	3-hydroxyacyl-CoA dehydrogenase
AREALGSMS7_RS21955	COG0183	Belongs to the thiolase family
AREALGSMS7_RS21960	COG1960	acyl-CoA dehydrogenase activity
AREALGSMS7_RS21965	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS21970	COG4251	negative regulation of phosphorylation
AREALGSMS7_RS21975	COG0784	Response regulator, receiver
AREALGSMS7_RS21985	COG1233	COG1233 Phytoene dehydrogenase and related
AREALGSMS7_RS21995	COG1215	transferase activity, transferring glycosyl groups
AREALGSMS7_RS22005	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AREALGSMS7_RS22040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AREALGSMS7_RS22045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AREALGSMS7_RS22055	COG1595	DNA-templated transcription, initiation
AREALGSMS7_RS22060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AREALGSMS7_RS22100	COG0156	8-amino-7-oxononanoate synthase activity
AREALGSMS7_RS22115	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AREALGSMS7_RS22125	COG0133	tryptophan synthase activity
AREALGSMS7_RS22140	COG2308	Evidence 4 Homologs of previously reported genes of
AREALGSMS7_RS22155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AREALGSMS7_RS22160	COG1393	Belongs to the ArsC family
AREALGSMS7_RS22185	COG1301	dicarboxylic acid transport
AREALGSMS7_RS22190	COG1301	dicarboxylic acid transport
AREALGSMS7_RS22195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AREALGSMS7_RS22205	COG0247	lactate metabolic process
AREALGSMS7_RS22205	COG0277	FAD linked oxidase domain protein
AREALGSMS7_RS22215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AREALGSMS7_RS22255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AREALGSMS7_RS22270	COG0405	Gamma-glutamyltransferase
AREALGSMS7_RS22290	COG1063	alcohol dehydrogenase
AREALGSMS7_RS22295	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AREALGSMS7_RS22320	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AREALGSMS7_RS22325	COG1063	alcohol dehydrogenase
AREALGSMS7_RS22330	COG2721	sulfolactate sulfo-lyase activity
AREALGSMS7_RS22335	COG3618	amidohydrolase
AREALGSMS7_RS22340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AREALGSMS7_RS22355	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AREALGSMS7_RS22360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AREALGSMS7_RS22375	COG0438	transferase activity, transferring glycosyl groups
AREALGSMS7_RS22375	COG0297	glycogen (starch) synthase activity
AREALGSMS7_RS22405	COG3394	polysaccharide catabolic process
AREALGSMS7_RS22415	COG0438	transferase activity, transferring glycosyl groups
AREALGSMS7_RS22455	COG0443	Heat shock 70 kDa protein
AREALGSMS7_RS22475	COG1760	l-serine dehydratase
AREALGSMS7_RS22495	COG0823	Involved in the tonB-independent uptake of proteins
AREALGSMS7_RS22505	COG0584	glycerophosphoryl diester phosphodiesterase
AREALGSMS7_RS22515	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AREALGSMS7_RS22520	COG0564	pseudouridine synthase activity
AREALGSMS7_RS22535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AREALGSMS7_RS22540	COG0473	3-isopropylmalate dehydrogenase activity
AREALGSMS7_RS22570	COG0488	(ABC) transporter
AREALGSMS7_RS22580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AREALGSMS7_RS22585	COG0300	oxidoreductase activity
AREALGSMS7_RS22635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AREALGSMS7_RS22655	COG0542	response to heat
AREALGSMS7_RS22680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AREALGSMS7_RS22685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AREALGSMS7_RS22690	COG0673	inositol 2-dehydrogenase activity
AREALGSMS7_RS22695	COG1250	3-hydroxyacyl-CoA dehydrogenase
AREALGSMS7_RS22700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AREALGSMS7_RS22705	COG2176	DNA-directed DNA polymerase activity
AREALGSMS7_RS22710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AREALGSMS7_RS22715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AREALGSMS7_RS22720	COG3265	gluconokinase activity
AREALGSMS7_RS22735	COG0237	dephospho-CoA kinase activity
AREALGSMS7_RS22745	COG0463	Glycosyl transferase, family 2
AREALGSMS7_RS22745	COG1216	Glycosyl transferase, family 2
AREALGSMS7_RS22750	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AREALGSMS7_RS22755	COG0497	DNA recombination
AREALGSMS7_RS22780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AREALGSMS7_RS22790	COG0737	Belongs to the 5'-nucleotidase family
AREALGSMS7_RS22795	COG0737	Belongs to the 5'-nucleotidase family
AREALGSMS7_RS22800	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AREALGSMS7_RS22835	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AREALGSMS7_RS22845	COG2890	protein-(glutamine-N5) methyltransferase activity
AREALGSMS7_RS22855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AREALGSMS7_RS22855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AREALGSMS7_RS22860	COG1011	Hydrolase
AREALGSMS7_RS22865	COG0697	spore germination
AREALGSMS7_RS22870	COG1739	Uncharacterized protein family UPF0029
AREALGSMS7_RS22880	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AREALGSMS7_RS22885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AREALGSMS7_RS22890	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AREALGSMS7_RS22900	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AREALGSMS7_RS22910	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AREALGSMS7_RS22930	COG0336	Belongs to the RNA methyltransferase TrmD family
AREALGSMS7_RS22935	COG0335	large ribosomal subunit rRNA binding
AREALGSMS7_RS22995	COG1363	Peptidase, m42
AREALGSMS7_RS23000	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AREALGSMS7_RS23015	COG0124	histidyl-tRNA synthetase
AREALGSMS7_RS23025	COG0359	binds to the 23S rRNA
AREALGSMS7_RS23030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AREALGSMS7_RS23035	COG0360	Binds together with S18 to 16S ribosomal RNA
AREALGSMS7_RS23040	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS23045	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AREALGSMS7_RS23055	COG1295	ribonuclease BN
AREALGSMS7_RS23070	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AREALGSMS7_RS23075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AREALGSMS7_RS23095	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AREALGSMS7_RS23105	COG0513	Belongs to the DEAD box helicase family
AREALGSMS7_RS23115	COG0366	Alpha amylase catalytic
AREALGSMS7_RS23120	COG1408	metallophosphoesterase
AREALGSMS7_RS23140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AREALGSMS7_RS23150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AREALGSMS7_RS23155	COG0668	transmembrane transport
AREALGSMS7_RS23205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AREALGSMS7_RS23230	COG0363	glucosamine-6-phosphate deaminase activity
AREALGSMS7_RS23235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AREALGSMS7_RS23240	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AREALGSMS7_RS23275	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS23320	COG0662	Cupin 2, conserved barrel domain protein
AREALGSMS7_RS23320	COG2207	Transcriptional regulator
AREALGSMS7_RS23325	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AREALGSMS7_RS23330	COG0513	Belongs to the DEAD box helicase family
AREALGSMS7_RS23340	COG2808	Putative FMN-binding domain
AREALGSMS7_RS23345	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AREALGSMS7_RS23355	COG3279	Response regulator of the LytR AlgR family
AREALGSMS7_RS23405	COG2345	Transcriptional regulator
AREALGSMS7_RS23415	COG1966	Carbon starvation protein
AREALGSMS7_RS23425	COG1862	Preprotein translocase
AREALGSMS7_RS23435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AREALGSMS7_RS23440	COG1132	(ABC) transporter
AREALGSMS7_RS23460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AREALGSMS7_RS23475	COG2318	DinB family
AREALGSMS7_RS23480	COG0450	alkyl hydroperoxide reductase
AREALGSMS7_RS23485	COG1278	Cold shock
AREALGSMS7_RS23490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AREALGSMS7_RS23500	COG2326	polyphosphate kinase activity
AREALGSMS7_RS23510	COG2204	response regulator
AREALGSMS7_RS23520	COG3264	Mechanosensitive ion channel
AREALGSMS7_RS23520	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AREALGSMS7_RS23525	COG1668	transmembrane transport
AREALGSMS7_RS23530	COG4152	abc transporter atp-binding protein
AREALGSMS7_RS23540	COG0484	heat shock protein binding
AREALGSMS7_RS23545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AREALGSMS7_RS23555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AREALGSMS7_RS23555	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AREALGSMS7_RS23565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AREALGSMS7_RS23580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AREALGSMS7_RS23585	COG0347	Belongs to the P(II) protein family
AREALGSMS7_RS23590	COG0004	ammonium transporteR
AREALGSMS7_RS23610	COG1522	sequence-specific DNA binding
AREALGSMS7_RS23620	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AREALGSMS7_RS23620	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AREALGSMS7_RS23620	COG1703	isobutyryl-CoA mutase activity
AREALGSMS7_RS23625	COG0788	formyltetrahydrofolate deformylase activity
AREALGSMS7_RS23645	COG0284	orotidine-5'-phosphate decarboxylase activity
AREALGSMS7_RS23650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AREALGSMS7_RS23660	COG3842	ATPase activity
AREALGSMS7_RS23685	COG0174	glutamine synthetase
AREALGSMS7_RS23705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AREALGSMS7_RS23715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AREALGSMS7_RS23720	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS23720	COG0516	GMP reductase activity
AREALGSMS7_RS23725	COG2195	Cleaves the N-terminal amino acid of tripeptides
AREALGSMS7_RS23740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AREALGSMS7_RS23745	COG0501	Belongs to the peptidase M48B family
AREALGSMS7_RS23750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AREALGSMS7_RS23755	COG0735	belongs to the Fur family
AREALGSMS7_RS23760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AREALGSMS7_RS23770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AREALGSMS7_RS23790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AREALGSMS7_RS23810	COG1418	mRNA catabolic process
AREALGSMS7_RS23845	COG1104	cysteine desulfurase activity
AREALGSMS7_RS23885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AREALGSMS7_RS23895	COG3119	arylsulfatase activity
AREALGSMS7_RS23900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AREALGSMS7_RS23920	COG0116	Belongs to the methyltransferase superfamily
AREALGSMS7_RS23935	COG1272	protein, Hemolysin III
AREALGSMS7_RS23940	COG4206	TonB-dependent receptor
AREALGSMS7_RS23980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AREALGSMS7_RS23985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AREALGSMS7_RS23990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AREALGSMS7_RS23995	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AREALGSMS7_RS24010	COG0561	phosphatase activity
AREALGSMS7_RS24015	COG2207	Transcriptional regulator
AREALGSMS7_RS24040	COG0825	malonyl-CoA metabolic process
AREALGSMS7_RS24055	COG0343	queuine tRNA-ribosyltransferase activity
AREALGSMS7_RS24065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AREALGSMS7_RS24085	COG0500	methyltransferase
AREALGSMS7_RS24090	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AREALGSMS7_RS24095	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AREALGSMS7_RS24130	COG3385	transposase activity
AREALGSMS7_RS24140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AREALGSMS7_RS24150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AREALGSMS7_RS24155	COG0714	Associated with various cellular activities
AREALGSMS7_RS24195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AREALGSMS7_RS24210	COG0552	protein localization to endoplasmic reticulum
AREALGSMS7_RS24220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AREALGSMS7_RS24225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AREALGSMS7_RS24230	COG1546	Belongs to the CinA family
AREALGSMS7_RS24230	COG1058	Belongs to the CinA family
AREALGSMS7_RS24240	COG0179	Fumarylacetoacetate (FAA) hydrolase
AREALGSMS7_RS24245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AREALGSMS7_RS24250	COG0508	dehydrogenase complex catalyzes the overall conversion of
AREALGSMS7_RS24255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AREALGSMS7_RS24260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AREALGSMS7_RS24265	COG0326	Molecular chaperone. Has ATPase activity
AREALGSMS7_RS24275	COG2258	MOSC domain
AREALGSMS7_RS24285	COG2207	Transcriptional regulator
AREALGSMS7_RS24285	COG1917	Cupin 2, conserved barrel domain protein
AREALGSMS7_RS24300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AREALGSMS7_RS24320	COG0561	phosphatase activity
AREALGSMS7_RS24340	COG1482	cell wall glycoprotein biosynthetic process
AREALGSMS7_RS24350	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AREALGSMS7_RS24385	COG2816	NAD+ diphosphatase activity
AREALGSMS7_RS24395	COG1819	glycosyl
AREALGSMS7_RS24400	COG1484	DNA-dependent DNA replication
AREALGSMS7_RS24405	COG4584	PFAM Integrase catalytic
AREALGSMS7_RS24415	COG0517	IMP dehydrogenase activity
AREALGSMS7_RS24420	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS24505	COG1192	Involved in chromosome partitioning
AREALGSMS7_RS24515	COG1475	DNA binding
AREALGSMS7_RS24535	COG0629	single-stranded DNA binding
AREALGSMS7_RS24555	COG2003	Belongs to the UPF0758 family
AREALGSMS7_RS24620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AREALGSMS7_RS24625	COG0739	heme binding
AREALGSMS7_RS24625	COG0741	lytic transglycosylase activity
AREALGSMS7_RS24625	COG1196	nuclear chromosome segregation
AREALGSMS7_RS24725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AREALGSMS7_RS24730	COG4974	Belongs to the 'phage' integrase family
AREALGSMS7_RS24740	COG3385	transposase activity
AREALGSMS7_RS24745	COG1595	DNA-templated transcription, initiation
AREALGSMS7_RS24760	COG2249	NAD(P)H dehydrogenase (quinone) activity
AREALGSMS7_RS24770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity