locus-tag	class	description
E3U36_RS00015	ENOG4108NK4	UPF0266 membrane protein
E3U36_RS00020	ENOG4105F3R	pts system mannose fructose sorbose family iid
E3U36_RS00025	ENOG4105ETZ	PTS System
E3U36_RS00030	ENOG4105DAS	pts system
E3U36_RS00040	ENOG4107R11	Transcriptional regulator
E3U36_RS00050	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E3U36_RS00055	ENOG4105ERU	peptidase
E3U36_RS00060	ENOG4105UBK	short-chain dehydrogenase reductase
E3U36_RS00080	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E3U36_RS00085	ENOG4105DB7	PHP domain protein
E3U36_RS00095	ENOG4108EFP	Anthranilate synthase component II
E3U36_RS00100	ENOG4108EFP	Anthranilate synthase component II
E3U36_RS00115	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E3U36_RS00150	ENOG4105CE4	GlcNAc 6-P deacetylase
E3U36_RS00180	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E3U36_RS00185	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E3U36_RS00190	ENOG4105C9A	Phoh family
E3U36_RS00195	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E3U36_RS00200	ENOG4108JU5	Magnesium and cobalt efflux protein
E3U36_RS00205	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E3U36_RS00215	ENOG4105C8T	Leucyl-tRNA synthetase
E3U36_RS00220	ENOG4108U2H	Rare lipoprotein B
E3U36_RS00225	ENOG4105DJF	DNA polymerase III, delta' subunit
E3U36_RS00235	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
E3U36_RS00240	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E3U36_RS00245	ENOG4105CJN	penicillin-binding protein
E3U36_RS00250	ENOG4105CNI	cell division protein FtsW
E3U36_RS00255	ENOG4105K6T	rare lipoprotein A
E3U36_RS00260	ENOG4105K6T	rare lipoprotein A
E3U36_RS00265	ENOG4105DZ1	carboxypeptidase
E3U36_RS00270	ENOG4108Z43	UPF0250 protein
E3U36_RS00275	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E3U36_RS00280	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E3U36_RS00295	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E3U36_RS00305	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
E3U36_RS00315	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
E3U36_RS00330	ENOG4108IJ7	Glycine betaine
E3U36_RS00335	ENOG4108HQS	Glycine betaine
E3U36_RS00340	ENOG4105GIJ	Glycine betaine
E3U36_RS00360	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E3U36_RS00365	ENOG4105W0Z	cytoplasmic protein
E3U36_RS00380	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
E3U36_RS00390	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E3U36_RS00395	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E3U36_RS00400	ENOG4105CJN	penicillin-binding protein
E3U36_RS00405	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E3U36_RS00410	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E3U36_RS00415	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E3U36_RS00420	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E3U36_RS00425	ENOG4105CNI	cell division protein FtsW
E3U36_RS00430	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E3U36_RS00435	ENOG4105DFU	Cell wall formation (By similarity)
E3U36_RS00440	ENOG4105CPF	Cell wall formation (By similarity)
E3U36_RS00445	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E3U36_RS00450	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E3U36_RS00455	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E3U36_RS00460	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3U36_RS00470	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
E3U36_RS00475	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E3U36_RS00480	ENOG4105M6F	mutator MutT protein
E3U36_RS00485	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E3U36_RS00490	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
E3U36_RS00495	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
E3U36_RS00530	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E3U36_RS00535	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E3U36_RS00565	ENOG4105D9M	gamma-glutamylcysteine synthetase
E3U36_RS00570	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
E3U36_RS00590	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3U36_RS00600	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E3U36_RS00610	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E3U36_RS00635	ENOG4105EV9	Alpha Beta Hydrolase
E3U36_RS00650	ENOG4105CIC	tryptophan-specific transport protein
E3U36_RS00655	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
E3U36_RS00660	ENOG4105HMI	Membrane
E3U36_RS00670	ENOG4108IQI	permease
E3U36_RS00680	ENOG4105EHG	Permease protein
E3U36_RS00710	ENOG4105CUB	amino acid
E3U36_RS00715	ENOG4105CJB	Exodeoxyribonuclease I
E3U36_RS00760	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E3U36_RS00770	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E3U36_RS00775	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E3U36_RS00780	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E3U36_RS00785	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E3U36_RS00790	ENOG4105C3F	Signal peptidase i
E3U36_RS00795	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E3U36_RS00800	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
E3U36_RS00805	ENOG4105VQK	sigma E regulatory protein, MucB RseB
E3U36_RS00815	ENOG4105EMN	RNA polymerase sigma factor
E3U36_RS00835	ENOG4105C1J	atp-dependent rna helicase
E3U36_RS00840	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
E3U36_RS00845	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E3U36_RS00850	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E3U36_RS00855	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E3U36_RS00865	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E3U36_RS00870	ENOG4105VDB	UPF0125 protein
E3U36_RS00875	ENOG4108Z1B	Cyclase dehydrase
E3U36_RS00880	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E3U36_RS00900	ENOG410679B	prophage CP4-57 regulatory protein alpA
E3U36_RS00960	ENOG4108MXD	gtp-binding protein
E3U36_RS00965	ENOG4108KZE	transcriptional regulator
E3U36_RS00980	ENOG4106549	Antirestriction protein
E3U36_RS00985	ENOG4108XS9	dna repair protein
E3U36_RS01035	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E3U36_RS01065	ENOG4105D49	3-dehydroquinate synthase
E3U36_RS01080	ENOG4105DJV	ribulose-phosphate 3-epimerase
E3U36_RS01085	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E3U36_RS01090	ENOG4105C31	Tryptophanyl-tRNA synthetase
E3U36_RS01105	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E3U36_RS01115	ENOG4105E2X	shikimate dehydrogenase
E3U36_RS01120	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E3U36_RS01135	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
E3U36_RS01140	ENOG4105C5X	domain protein
E3U36_RS01150	ENOG4105FCK	Membrane
E3U36_RS01155	ENOG4105C5S	asparaginyl-tRNA synthetase
E3U36_RS01160	ENOG4107RH7	Nicotinate phosphoribosyltransferase
E3U36_RS01170	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E3U36_RS01190	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
E3U36_RS01200	ENOG4105C25	Primosomal protein n'
E3U36_RS01220	ENOG41063M6	Cell Division Protein
E3U36_RS01230	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
E3U36_RS01235	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
E3U36_RS01250	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
E3U36_RS01265	ENOG4105X1N	Glycosyl transferase family 8
E3U36_RS01270	ENOG4106AH0	Glycosyl Transferase
E3U36_RS01275	ENOG4107543	(lipo)polysaccharide
E3U36_RS01280	ENOG4107RJ7	Glycosyl transferase (Group 1
E3U36_RS01310	ENOG4108Z33	Thiol disulfide Interchange Protein
E3U36_RS01315	ENOG4105C2M	dna polymerase I
E3U36_RS01325	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
E3U36_RS01335	ENOG4105CEN	a g-specific adenine glycosylase
E3U36_RS01340	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
E3U36_RS01345	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
E3U36_RS01390	ENOG4105CEY	Amp-dependent synthetase and ligase
E3U36_RS01400	ENOG41072GX	Peptidase M22 Glycoprotease
E3U36_RS01415	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
E3U36_RS01420	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
E3U36_RS01425	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
E3U36_RS01430	ENOG4106KNT	transcriptional regulator
E3U36_RS01440	ENOG4106KNT	transcriptional regulator
E3U36_RS01455	ENOG4108K4B	hydrolase
E3U36_RS01460	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E3U36_RS01515	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
E3U36_RS01520	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
E3U36_RS01525	ENOG4105WH1	Two component transcriptional regulator luxr family
E3U36_RS01540	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E3U36_RS01550	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E3U36_RS01555	ENOG4105M2J	Glutaredoxin
E3U36_RS01560	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E3U36_RS01565	ENOG4108UYE	Lactoylglutathione lyase
E3U36_RS01590	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E3U36_RS01595	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
E3U36_RS01610	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E3U36_RS01615	ENOG4105CFG	Acts as a chaperone (By similarity)
E3U36_RS01620	ENOG4106HK8	GPR1 FUN34 yaaH family protein
E3U36_RS01625	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E3U36_RS01630	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E3U36_RS01635	ENOG4105D1Q	UPF0246 protein
E3U36_RS01665	ENOG4108RH0	Crea protein
E3U36_RS01670	ENOG4105UEI	Transcriptional Regulator AraC Family
E3U36_RS01685	ENOG4105CVJ	phosphoglycerate mutase
E3U36_RS01695	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
E3U36_RS01700	ENOG4107SC1	transglycosylase
E3U36_RS01705	ENOG4107SC1	transglycosylase
E3U36_RS01720	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E3U36_RS01745	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
E3U36_RS01750	ENOG4105CIN	aminoacyl-histidine dipeptidase
E3U36_RS01755	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E3U36_RS01770	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
E3U36_RS01780	ENOG4105QVD	Flagella synthesis protein FlgN
E3U36_RS01800	ENOG4105ER2	Ompa motb domain protein
E3U36_RS01805	ENOG4107RD7	Flagellar Motor Protein, MotA
E3U36_RS01810	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
E3U36_RS01830	ENOG4105CK7	Sodium proline symporter
E3U36_RS01840	ENOG4108M9K	flagella biosynthesis protein FliZ
E3U36_RS01845	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3U36_RS01860	ENOG4105DTS	flagellar hook-associated
E3U36_RS01870	ENOG4105MQ3	flagellar protein FliS
E3U36_RS01875	ENOG4108JIR	Flagellum-specific ATP synthase
E3U36_RS01890	ENOG4105WF4	Flagellar hook-length control protein
E3U36_RS01910	ENOG4105DD5	Flagellar motor switch protein
E3U36_RS01930	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E3U36_RS01940	ENOG4105C0A	alcohol dehydrogenase
E3U36_RS01945	ENOG4107SRH	Nad-dependent epimerase dehydratase
E3U36_RS01965	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3U36_RS01970	ENOG4105C34	Pseudouridine synthase
E3U36_RS01975	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E3U36_RS01980	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3U36_RS02010	ENOG4105D4A	Cell wall formation (By similarity)
E3U36_RS02015	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
E3U36_RS02020	ENOG4105CS9	pantothenic acid kinase
E3U36_RS02045	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E3U36_RS02050	ENOG4105PM1	preprotein translocase subunit SecE
E3U36_RS02055	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E3U36_RS02060	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E3U36_RS02065	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E3U36_RS02070	ENOG4108VZM	50s ribosomal protein L10
E3U36_RS02075	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E3U36_RS02080	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3U36_RS02085	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3U36_RS02100	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E3U36_RS02115	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E3U36_RS02125	ENOG4105E09	nadh pyrophosphatase
E3U36_RS02155	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E3U36_RS02165	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E3U36_RS02170	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
E3U36_RS02175	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E3U36_RS02180	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E3U36_RS02185	ENOG4105VIE	preprotein translocase, subunit YajC
E3U36_RS02195	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E3U36_RS02200	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
E3U36_RS02205	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E3U36_RS02210	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E3U36_RS02215	ENOG4107YIM	Involved in the transcription termination process (By similarity)
E3U36_RS02220	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E3U36_RS02225	ENOG4108ZAI	phosphatidylglycerophosphatase a
E3U36_RS02230	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E3U36_RS02235	ENOG4105CTB	Polyprenyl synthetase
E3U36_RS02245	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
E3U36_RS02255	ENOG4108VPT	UPF0234 protein
E3U36_RS02265	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E3U36_RS02270	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
E3U36_RS02275	ENOG4105CCU	oxidase (Subunit III)
E3U36_RS02280	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E3U36_RS02285	ENOG4105E2S	oxidase) subunit II
E3U36_RS02310	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
E3U36_RS02315	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
E3U36_RS02325	ENOG41090ED	Protein with unknown function (DUF469)
E3U36_RS02330	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E3U36_RS02355	ENOG4105CMR	udp-glucose 4-epimerase
E3U36_RS02365	ENOG4105C79	DNA protecting protein DprA
E3U36_RS02375	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E3U36_RS02380	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E3U36_RS02385	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E3U36_RS02390	ENOG4105C1A	potassium transporter peripheral membrane
E3U36_RS02395	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E3U36_RS02400	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
E3U36_RS02405	ENOG4105W1Y	Transcriptional regulator
E3U36_RS02410	ENOG4108ZT0	50S ribosomal protein l17
E3U36_RS02420	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E3U36_RS02425	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E3U36_RS02430	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E3U36_RS02435	ENOG41067V7	50S ribosomal protein L36
E3U36_RS02440	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E3U36_RS02445	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E3U36_RS02450	ENOG4105VPB	50S ribosomal protein L30
E3U36_RS02455	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E3U36_RS02460	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E3U36_RS02465	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E3U36_RS02470	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E3U36_RS02475	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E3U36_RS02480	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E3U36_RS02490	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E3U36_RS02495	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E3U36_RS02500	ENOG41083MP	50s ribosomal protein l29
E3U36_RS02505	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E3U36_RS02510	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E3U36_RS02520	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E3U36_RS02525	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E3U36_RS02530	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E3U36_RS02535	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E3U36_RS02540	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E3U36_RS02550	ENOG4108UQY	Iron-storage protein
E3U36_RS02560	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E3U36_RS02565	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E3U36_RS02570	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E3U36_RS02575	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E3U36_RS02580	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E3U36_RS02585	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E3U36_RS02590	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
E3U36_RS02595	ENOG4105WWK	YheO domain protein
E3U36_RS02600	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E3U36_RS02720	ENOG4105KUS	lysozyme
E3U36_RS02860	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
E3U36_RS02890	ENOG4106665	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
E3U36_RS02895	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
E3U36_RS02910	ENOG4105DH7	May be involved in recombination (By similarity)
E3U36_RS02960	ENOG4105VRT	cytoplasmic protein
E3U36_RS02975	ENOG4105D9N	nucleoside
E3U36_RS02980	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E3U36_RS02985	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
E3U36_RS02995	ENOG4105C6T	cysteine synthase
E3U36_RS03005	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
E3U36_RS03010	ENOG4105C5Y	PTS System
E3U36_RS03030	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E3U36_RS03035	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E3U36_RS03040	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E3U36_RS03045	ENOG4105N21	Membrane
E3U36_RS03050	ENOG4105CUT	histidyl-tRNA synthetase
E3U36_RS03055	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E3U36_RS03075	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E3U36_RS03090	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E3U36_RS03095	ENOG4105WVQ	Fe-S assembly protein IscX
E3U36_RS03100	ENOG4108ZIT	Ferredoxin, 2FE-2S
E3U36_RS03110	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E3U36_RS03120	ENOG4106MWK	domain protein
E3U36_RS03130	ENOG4107ZVW	dihydroneopterin aldolase
E3U36_RS03135	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
E3U36_RS03140	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E3U36_RS03145	ENOG4105VCC	30S ribosomal protein S21
E3U36_RS03150	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E3U36_RS03155	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3U36_RS03170	ENOG4105D0M	Protease HtpX homolog
E3U36_RS03175	ENOG4105XVG	cytoplasmic protein
E3U36_RS03195	ENOG4105DWK	Membrane
E3U36_RS03200	ENOG4107XM3	UPF0442 protein
E3U36_RS03215	ENOG4105RWS	endonuclease I
E3U36_RS03235	ENOG4105C3G	gtp-binding protein
E3U36_RS03250	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E3U36_RS03255	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
E3U36_RS03260	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
E3U36_RS03265	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E3U36_RS03270	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E3U36_RS03275	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E3U36_RS03280	ENOG41063JG	Transcriptional regulator
E3U36_RS03285	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E3U36_RS03290	ENOG4105N5T	Radical SAM Protein
E3U36_RS03300	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
E3U36_RS03305	ENOG4105F3T	(LipO)protein
E3U36_RS03340	ENOG4105CJR	Integral membrane protein (MviN
E3U36_RS03350	ENOG4107QI1	Mate efflux family protein
E3U36_RS03355	ENOG4108R6K	riboflavin synthase, subunit alpha
E3U36_RS03380	ENOG4105F52	Transcriptional regulator
E3U36_RS03385	ENOG4105ETE	Transcriptional regulator (LacI family
E3U36_RS03390	ENOG4105C75	arginyL-tRNA synthetase
E3U36_RS03400	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
E3U36_RS03405	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
E3U36_RS03410	ENOG4105WJG	Glutathione
E3U36_RS03415	ENOG4105C9M	aspartyl-trna synthetase
E3U36_RS03420	ENOG4108TIT	dATP pyrophosphohydrolase
E3U36_RS03425	ENOG4105CDY	transcriptional regulatory protein
E3U36_RS03430	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E3U36_RS03435	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E3U36_RS03440	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E3U36_RS03455	ENOG4105XIQ	Protein of unknown function (DUF2517)
E3U36_RS03460	ENOG4107QNR	UPF0135 protein
E3U36_RS03475	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E3U36_RS03485	ENOG4105E33	succinate dehydrogenase
E3U36_RS03490	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E3U36_RS03495	ENOG4105C7S	Dehydrogenase
E3U36_RS03500	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
E3U36_RS03505	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E3U36_RS03510	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E3U36_RS03515	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E3U36_RS03535	ENOG4105E02	MotA TolQ exbB proton channel
E3U36_RS03545	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
E3U36_RS03550	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E3U36_RS03555	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E3U36_RS03560	ENOG4105UFD	tol-pal system protein YbgF
E3U36_RS03575	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E3U36_RS03580	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
E3U36_RS03595	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E3U36_RS03625	ENOG4105W4M	Transport-associated protein
E3U36_RS03630	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E3U36_RS03635	ENOG41082RQ	UPF0102 protein
E3U36_RS03645	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E3U36_RS03710	ENOG4108VBZ	doxx family
E3U36_RS03730	ENOG4106W5V	Membrane
E3U36_RS03735	ENOG4105DU1	integral membrane protein, terc
E3U36_RS03750	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E3U36_RS03790	ENOG4105C8N	cysteinyl-tRNA synthetase
E3U36_RS03795	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E3U36_RS03800	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
E3U36_RS03820	ENOG4105E1F	short-chain dehydrogenase reductase
E3U36_RS03825	ENOG4107QR8	Thioredoxin
E3U36_RS03840	ENOG4108Z6Z	Transcriptional regulator
E3U36_RS03845	ENOG4105C59	p-type ATPase
E3U36_RS03850	ENOG4105MBR	gumn family
E3U36_RS03855	ENOG4108Z66	YbaK ebsC protein
E3U36_RS03870	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E3U36_RS03875	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E3U36_RS03885	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
E3U36_RS03890	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E3U36_RS03895	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E3U36_RS03905	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
E3U36_RS03910	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E3U36_RS03950	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E3U36_RS03955	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E3U36_RS03960	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E3U36_RS03965	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E3U36_RS03970	ENOG4105VG0	50S ribosomal protein l34
E3U36_RS03975	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E3U36_RS03980	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E3U36_RS03990	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3U36_RS03995	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E3U36_RS04000	ENOG4105F32	YngK protein
E3U36_RS04005	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E3U36_RS04010	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E3U36_RS04015	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E3U36_RS04020	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E3U36_RS04030	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E3U36_RS04035	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E3U36_RS04040	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E3U36_RS04050	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
E3U36_RS04055	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
E3U36_RS04070	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E3U36_RS04080	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E3U36_RS04085	ENOG4105QTB	Flavodoxin
E3U36_RS04090	ENOG4108VVK	transcriptional Regulator, AsnC
E3U36_RS04095	ENOG4105CU9	asparagine synthetase A
E3U36_RS04140	ENOG4105CVI	Transcriptional regulator
E3U36_RS04145	ENOG4108WFC	UPF0438 protein yifE
E3U36_RS04190	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E3U36_RS04205	ENOG4105C4R	Atp-dependent dna helicase
E3U36_RS04210	ENOG4105C9X	ppx gppa phosphatase
E3U36_RS04215	ENOG4105C1J	atp-dependent rna helicase
E3U36_RS04225	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E3U36_RS04230	ENOG4105ESV	Glycosyl transferase, family 4
E3U36_RS04235	ENOG4105SFE	lipopolysaccharide biosynthesis protein
E3U36_RS04240	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
E3U36_RS04245	ENOG4108IJ1	Dehydrogenase
E3U36_RS04250	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E3U36_RS04255	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
E3U36_RS04260	ENOG4108WJ1	acetyltransferase
E3U36_RS04265	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E3U36_RS04270	ENOG4105EGZ	biosynthesis protein
E3U36_RS04275	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
E3U36_RS04280	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
E3U36_RS04285	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
E3U36_RS04290	ENOG4105C85	amino acid
E3U36_RS04315	ENOG410601J	HemY protein
E3U36_RS04320	ENOG4105ECF	c-methyltransferase
E3U36_RS04325	ENOG41076E6	Uroporphyrinogen-III Synthase
E3U36_RS04330	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E3U36_RS04335	ENOG4107T0K	Adenylate cyclase
E3U36_RS04340	ENOG4105XQ6	frataxin-like protein
E3U36_RS04350	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E3U36_RS04355	ENOG4105CT0	Protein of unknown function, DUF484
E3U36_RS04365	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
E3U36_RS04370	ENOG4105C4R	Atp-dependent dna helicase
E3U36_RS04385	ENOG4107QUT	magnesium and cobalt transport protein CorA
E3U36_RS04395	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E3U36_RS04405	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E3U36_RS04410	ENOG4108EUD	Lysophospholipase
E3U36_RS04415	ENOG4105DQF	Hydrolase
E3U36_RS04425	ENOG4108TTM	chaperone
E3U36_RS04430	ENOG4105D03	DNA-3-methyladenine glycosylase II
E3U36_RS04445	ENOG4105CP7	Triose-phosphate isomerase
E3U36_RS04450	ENOG4105EBK	exported protein
E3U36_RS04460	ENOG4105DP0	ferredoxin-NADP reductase
E3U36_RS04465	ENOG4105E5M	Multidrug resistance protein D
E3U36_RS04495	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E3U36_RS04500	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E3U36_RS04505	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E3U36_RS04515	ENOG4105D16	lipopolysaccharide heptosyltransferase i
E3U36_RS04520	ENOG4105XA0	heptosyltransferase ii
E3U36_RS04525	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
E3U36_RS04530	ENOG4105PXI	polysaccharide deacetylase
E3U36_RS04535	ENOG41063SB	peptidase
E3U36_RS04540	ENOG4107YZP	Rhodanese domain protein
E3U36_RS04545	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
E3U36_RS04550	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
E3U36_RS04560	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E3U36_RS04580	ENOG4105E0F	Histidine kinase
E3U36_RS04585	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E3U36_RS04595	ENOG4105FMW	periplasmic
E3U36_RS04740	ENOG4107QQB	Ribonuclease E
E3U36_RS04745	ENOG4105EI2	Pseudouridine synthase
E3U36_RS04750	ENOG4108UHJ	MAF-like protein
E3U36_RS04760	ENOG4105VGS	50s ribosomal protein l32
E3U36_RS04765	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
E3U36_RS04770	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E3U36_RS04775	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E3U36_RS04780	ENOG4105CHR	reductase
E3U36_RS04785	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E3U36_RS04790	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3U36_RS04795	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
E3U36_RS04800	ENOG4105HHA	aminodeoxychorismate lyase
E3U36_RS04805	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
E3U36_RS04810	ENOG4107QRG	dna polymerase iii
E3U36_RS04815	ENOG4105F8V	Hydrolase, tatD family
E3U36_RS04820	ENOG4105K59	histidine triad (HIT) protein
E3U36_RS04825	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
E3U36_RS04860	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
E3U36_RS04870	ENOG4105CYW	agmatinase
E3U36_RS04885	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E3U36_RS04890	ENOG4105GPY	SprT protein
E3U36_RS04930	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E3U36_RS04940	ENOG4105CUZ	uba thif-type nad fad binding protein
E3U36_RS04945	ENOG4105C9B	Cysteine desulfurase
E3U36_RS04950	ENOG4105C9B	Cysteine desulfurase
E3U36_RS04955	ENOG4105C9B	Cysteine desulfurase
E3U36_RS04970	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
E3U36_RS04975	ENOG4105DE4	1-phosphofructokinase
E3U36_RS04990	ENOG4106H3A	restriction
E3U36_RS05095	ENOG4105EAH	synthase
E3U36_RS05100	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E3U36_RS05105	ENOG4105K46	50S ribosomal protein l27
E3U36_RS05110	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E3U36_RS05115	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E3U36_RS05120	ENOG4105HBR	Rna-binding protein
E3U36_RS05130	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E3U36_RS05135	ENOG4105EEI	dihydropteroate synthase
E3U36_RS05140	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E3U36_RS05145	ENOG4105NTZ	Preprotein translocase subunit SecG
E3U36_RS05160	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
E3U36_RS05165	ENOG4105CHV	Transcription elongation factor NusA
E3U36_RS05170	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E3U36_RS05175	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E3U36_RS05180	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E3U36_RS05190	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E3U36_RS05205	ENOG4105C1J	atp-dependent rna helicase
E3U36_RS05250	ENOG4108YYD	acetyltransferase
E3U36_RS05260	ENOG4108ZPB	UPF0306 protein
E3U36_RS05265	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
E3U36_RS05275	ENOG4105KME	endoribonuclease L-psp
E3U36_RS05280	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
E3U36_RS05295	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
E3U36_RS05300	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E3U36_RS05305	ENOG4105MYG	DNA polymerase iii, chi subunit
E3U36_RS05310	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E3U36_RS05315	ENOG4108M8S	permease YjgP YjgQ family protein
E3U36_RS05320	ENOG4108K5H	permease YjgP YjgQ family protein
E3U36_RS05325	ENOG4107R6D	beta-lactam binding protein AmpH
E3U36_RS05345	ENOG4105HVQ	Regulatory factor of maltose metabolism
E3U36_RS05355	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
E3U36_RS05375	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
E3U36_RS05385	ENOG4105ERG	peptidase m48, ste24p
E3U36_RS05390	ENOG4105C02	permease
E3U36_RS05395	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3U36_RS05420	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E3U36_RS05440	ENOG4108VMM	UPF0756 membrane protein
E3U36_RS05445	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
E3U36_RS05450	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
E3U36_RS05465	ENOG4105WD1	Membrane
E3U36_RS05470	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E3U36_RS05495	ENOG4105CW0	outer membrane usher protein
E3U36_RS05505	ENOG4105CW0	outer membrane usher protein
E3U36_RS05520	ENOG4105DWT	malate dehydrogenase (quinone)
E3U36_RS05550	ENOG41065CD	Exported protein
E3U36_RS05565	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
E3U36_RS05590	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
E3U36_RS05630	ENOG4105CJ2	(LipO)protein
E3U36_RS05650	ENOG4105CJ3	phosphate transporter
E3U36_RS05655	ENOG4105CBX	hi0933 family
E3U36_RS05670	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
E3U36_RS05675	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
E3U36_RS05685	ENOG4105C28	cystathionine
E3U36_RS05690	ENOG4107S6Z	Na H antiporter
E3U36_RS05695	ENOG4105D52	delta-aminolevulinic acid dehydratase
E3U36_RS05700	ENOG4107Z6W	Protein CrcB homolog
E3U36_RS05735	ENOG4105CK2	sodium dicarboxylate symporter
E3U36_RS05740	ENOG4105D2N	Aldolase
E3U36_RS05745	ENOG4105BZA	Phosphoglycerate kinase
E3U36_RS05750	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E3U36_RS05755	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E3U36_RS05765	ENOG4107RZZ	dna polymerase iii epsilon subunit
E3U36_RS05770	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E3U36_RS05775	ENOG4105D1A	Methyltransferase
E3U36_RS05780	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E3U36_RS05785	ENOG4105E9H	Lytic Murein transglycosylase
E3U36_RS05795	ENOG4105E66	phosphoriboisomerase A
E3U36_RS05810	ENOG4105D64	Mechanosensitive ion channel
E3U36_RS05840	ENOG4107QN2	dihydrolipoyl dehydrogenase
E3U36_RS05845	ENOG4107QSN	dihydrolipoamide acetyltransferase
E3U36_RS05850	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E3U36_RS05875	ENOG4105CGF	Aromatic amino acid aminotransferase
E3U36_RS05885	ENOG4105CDU	Replicative dna helicase
E3U36_RS05895	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E3U36_RS05945	ENOG4105UEI	Transcriptional Regulator AraC Family
E3U36_RS05960	ENOG4105C85	amino acid
E3U36_RS05990	ENOG4105C6Z	Gluconate
E3U36_RS06000	ENOG4105MYN	Zinc uptake regulation protein
E3U36_RS06005	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
E3U36_RS06015	ENOG4105E55	glycerol-3-phosphate acyltransferase
E3U36_RS06020	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E3U36_RS06030	ENOG4107QP8	phosphohexose isomerase
E3U36_RS06035	ENOG4105CFH	Aspartokinase
E3U36_RS06060	ENOG4107QP3	malate synthase g
E3U36_RS06100	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
E3U36_RS06140	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E3U36_RS06145	ENOG4105T95	Thiol disulfide interChange protein
E3U36_RS06150	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E3U36_RS06160	ENOG4105CRK	lysyL-tRNA synthetase
E3U36_RS06165	ENOG4105WPN	DNA integration recombination invertion protein
E3U36_RS06195	ENOG4107QIZ	NADH dehydrogenase
E3U36_RS06200	ENOG4108IEH	NADH dehydrogenase subunit g
E3U36_RS06210	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3U36_RS06230	ENOG4107UFS	subunit j
E3U36_RS06240	ENOG4105D65	subunit l
E3U36_RS06250	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3U36_RS06275	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
E3U36_RS06295	ENOG4105E0U	tyrosine-specific transport protein
E3U36_RS06305	ENOG4105XPH	Ferredoxin
E3U36_RS06310	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3U36_RS06315	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3U36_RS06320	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E3U36_RS06325	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3U36_RS06330	ENOG4105BZU	Histidine kinase
E3U36_RS06345	ENOG41068CG	regulatoR
E3U36_RS06350	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
E3U36_RS06370	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E3U36_RS06375	ENOG4106V8H	Nucleoid-associated protein
E3U36_RS06385	ENOG4105E68	Sulfatase
E3U36_RS06435	ENOG4105JIM	Phosphatidylserine synthase
E3U36_RS06460	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E3U36_RS06465	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
E3U36_RS06475	ENOG4105CN1	protease
E3U36_RS06480	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
E3U36_RS06485	ENOG4108ZGC	gaf domain protein
E3U36_RS06495	ENOG4105WT8	Protein of unknown function (DUF1480)
E3U36_RS06520	ENOG4105CRQ	synthase (Component I)
E3U36_RS06525	ENOG4105X5C	UPF0181 protein
E3U36_RS06530	ENOG4105VBS	Inherit from NOG: Secreted protein
E3U36_RS06535	ENOG4105MPK	DNA polymerase III subunit theta
E3U36_RS06555	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E3U36_RS06565	ENOG4105EYA	deoxyribonuclease
E3U36_RS06570	ENOG4105D9N	nucleoside
E3U36_RS06575	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
E3U36_RS06580	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
E3U36_RS06585	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
E3U36_RS06605	ENOG4105EAC	phosphoserine phosphatase
E3U36_RS06610	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E3U36_RS06615	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
E3U36_RS06620	ENOG4105C5H	ABC transporter
E3U36_RS06635	ENOG4105CFP	Peptidase U32
E3U36_RS06660	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
E3U36_RS06670	ENOG4105CKT	filamentous hemagglutinin
E3U36_RS06700	ENOG4105PY6	Phenolic acid decarboxylase
E3U36_RS06705	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E3U36_RS06710	ENOG4108UUM	single-stranded DNA-binding protein
E3U36_RS06725	ENOG4105XEA	Tetr family transcriptional regulator
E3U36_RS06765	ENOG4105EMK	carboxylate amino acid amine transporter
E3U36_RS06790	ENOG4105DQY	intracellular growth attenuator
E3U36_RS06795	ENOG4105VEJ	Heat shock protein
E3U36_RS06825	ENOG4105UYK	outer membrane protein a
E3U36_RS06830	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
E3U36_RS06835	ENOG4105DAN	ATP-dependent protease
E3U36_RS06840	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
E3U36_RS06845	ENOG4108Q2G	(LipO)protein
E3U36_RS06860	ENOG4105C5H	ABC transporter
E3U36_RS06865	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
E3U36_RS06875	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
E3U36_RS06885	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E3U36_RS06895	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E3U36_RS06900	ENOG4108MG3	formate dehydrogenase
E3U36_RS06975	ENOG4105CW0	outer membrane usher protein
E3U36_RS06990	ENOG4105DJ4	phosphatidylserine decarboxylase
E3U36_RS06995	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E3U36_RS07000	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E3U36_RS07015	ENOG4105K8N	protein family UPF0079, ATPase
E3U36_RS07020	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E3U36_RS07025	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E3U36_RS07030	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E3U36_RS07035	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E3U36_RS07040	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E3U36_RS07045	ENOG4107QJR	hflk protein
E3U36_RS07050	ENOG4105EPW	hflc protein
E3U36_RS07055	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E3U36_RS07060	ENOG4105KPV	Transcriptional regulator
E3U36_RS07065	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E3U36_RS07070	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E3U36_RS07075	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
E3U36_RS07080	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
E3U36_RS07085	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E3U36_RS07090	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E3U36_RS07095	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E3U36_RS07105	ENOG41061GZ	Protein of unknown function (DUF1107)
E3U36_RS07110	ENOG4105C9K	Endothelin-converting enzyme 1
E3U36_RS07135	ENOG4105F0N	pyrophosphate phospho-hydrolase
E3U36_RS07150	ENOG4107URF	beta-phospho-glucomutase
E3U36_RS07210	ENOG4105DQ5	transport system permease protein
E3U36_RS07220	ENOG4105E0A	ABC, transporter
E3U36_RS07245	ENOG4105J5G	Transferase hexapeptide repeat containing protein
E3U36_RS07250	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E3U36_RS07290	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E3U36_RS07310	ENOG4108QY5	Ferric enterobactin transport protein
E3U36_RS07320	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
E3U36_RS07330	ENOG41090BQ	Glutaredoxin
E3U36_RS07335	ENOG4105X20	member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress
E3U36_RS07340	ENOG4108RMJ	sensory transduction regulator
E3U36_RS07350	ENOG4105DMR	ABC, transporter
E3U36_RS07355	ENOG4105GBT	ABC transporter
E3U36_RS07360	ENOG4106PMH	Extracellular solute-binding protein family 3
E3U36_RS07365	ENOG4105E5Z	arginine transporter ATP-binding subunit
E3U36_RS07395	ENOG4105VEQ	Cold shock protein
E3U36_RS07400	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E3U36_RS07405	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3U36_RS07415	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E3U36_RS07420	ENOG4108JJ8	(ABC) transporter
E3U36_RS07425	ENOG4108JJ9	ABC, transporter
E3U36_RS07430	ENOG4105C3M	thioredoxin reductase
E3U36_RS07435	ENOG4105EW9	transcriptional regulator AsnC family
E3U36_RS07440	ENOG4105CNU	cell division protein FtsK
E3U36_RS07445	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E3U36_RS07450	ENOG4105D1H	recombination factor protein RarA
E3U36_RS07455	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E3U36_RS07470	ENOG4105HDK	L-asparaginase
E3U36_RS07475	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E3U36_RS07480	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E3U36_RS07485	ENOG4105CAT	Cytidine monophosphate kinase
E3U36_RS07490	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E3U36_RS07495	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E3U36_RS07505	ENOG4105E3A	(ABC) transporter
E3U36_RS07510	ENOG4105DA5	(ABC) transporter
E3U36_RS07520	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E3U36_RS07535	ENOG4108ZRK	uncharacterized protein yacC
E3U36_RS07540	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
E3U36_RS07545	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
E3U36_RS07565	ENOG4105UQX	Mate efflux family protein
E3U36_RS07570	ENOG4105CKI	cobalamin synthesis protein
E3U36_RS07575	ENOG4105VCD	cytoplasmic protein
E3U36_RS07605	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E3U36_RS07620	ENOG4108K5P	(LipO)protein
E3U36_RS07625	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E3U36_RS07630	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E3U36_RS07645	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E3U36_RS07650	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
E3U36_RS07675	ENOG4105C85	amino acid
E3U36_RS07680	ENOG4107NA1	Endonuclease Exonuclease phosphatase
E3U36_RS07715	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E3U36_RS07725	ENOG4108T8B	Protein of unknown function (DUF1481)
E3U36_RS07735	ENOG4105R2J	Conserved Protein
E3U36_RS07740	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
E3U36_RS07765	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
E3U36_RS07775	ENOG4105C9Q	fumarate hydratase class II
E3U36_RS07780	ENOG4105EIP	mannose-6-phosphate isomerase
E3U36_RS07785	ENOG4106J39	exported protein
E3U36_RS07805	ENOG4105DGN	Electron transport complex
E3U36_RS07815	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
E3U36_RS07825	ENOG4108UQQ	Electron transport complex
E3U36_RS07835	ENOG4105CSM	endonuclease III
E3U36_RS07840	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
E3U36_RS07860	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
E3U36_RS07865	ENOG4105CFV	Tetratricopeptide repeat protein
E3U36_RS07870	ENOG4105Q4A	inner membrane protein yciS
E3U36_RS07875	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
E3U36_RS07890	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
E3U36_RS07895	ENOG4105EHG	Permease protein
E3U36_RS07930	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E3U36_RS07935	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
E3U36_RS07940	ENOG4105MDZ	Transcriptional activator rfaH
E3U36_RS07945	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E3U36_RS07950	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
E3U36_RS07955	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E3U36_RS07960	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E3U36_RS07970	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E3U36_RS07975	ENOG4105CGY	Dna recombination protein
E3U36_RS07980	ENOG4108KF1	Membrane
E3U36_RS08030	ENOG4105C0W	non-ribosomal peptide synthetase
E3U36_RS08065	ENOG4105DGW	oligopeptidase A
E3U36_RS08070	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
E3U36_RS08130	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
E3U36_RS08135	ENOG4105C5Q	Transcriptional regulator
E3U36_RS08145	ENOG4107NQ8	LysR family Transcriptional regulator
E3U36_RS08175	ENOG4105PQ6	UPF0208 membrane protein
E3U36_RS08180	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E3U36_RS08185	ENOG4105C6K	Malic enzyme
E3U36_RS08240	ENOG410903C	(LipO)protein
E3U36_RS08250	ENOG4105KZW	UPF0381 protein
E3U36_RS08255	ENOG4105CHU	acetyl-coa acetyltransferase
E3U36_RS08260	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3U36_RS08270	ENOG4108DG9	Smr protein MutS2
E3U36_RS08275	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E3U36_RS08285	ENOG4108BPE	-transporting atpase
E3U36_RS08290	ENOG4105MH2	YfcL protein
E3U36_RS08305	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
E3U36_RS08315	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
E3U36_RS08320	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3U36_RS08330	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
E3U36_RS08340	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E3U36_RS08345	ENOG4105DQR	SNARE associated Golgi
E3U36_RS08350	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E3U36_RS08355	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E3U36_RS08360	ENOG4108S3P	Sporulation domain protein
E3U36_RS08365	ENOG4105E96	Colicin v production protein
E3U36_RS08375	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E3U36_RS08390	ENOG4107QYX	exodeoxyribonuclease v alpha
E3U36_RS08395	ENOG4107QKA	exodeoxyribonuclease V beta
E3U36_RS08405	ENOG4105DSY	exodeoxyribonuclease V, gamma
E3U36_RS08440	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E3U36_RS08445	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E3U36_RS08450	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E3U36_RS08455	ENOG4105DP9	ABC transporter
E3U36_RS08460	ENOG4106SMU	thiamine transporter membrane protein
E3U36_RS08465	ENOG4107T0D	ABC, transporter
E3U36_RS08480	ENOG4105D3G	Pseudouridine synthase
E3U36_RS08485	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
E3U36_RS08490	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E3U36_RS08495	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E3U36_RS08500	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E3U36_RS08505	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E3U36_RS08510	ENOG4105NWN	ApaG protein
E3U36_RS08515	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E3U36_RS08520	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
E3U36_RS08530	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
E3U36_RS08535	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3U36_RS08540	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3U36_RS08550	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E3U36_RS08565	ENOG4105F1G	UPF0441 protein
E3U36_RS08570	ENOG4106032	Glutathionylspermidine synthase
E3U36_RS08580	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E3U36_RS08605	ENOG4105W0E	50S ribosomal protein L33
E3U36_RS08610	ENOG4105KDC	50s ribosomal protein l28
E3U36_RS08615	ENOG4105W5Q	DNA repair protein (RadC
E3U36_RS08620	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E3U36_RS08625	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E3U36_RS08630	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
E3U36_RS08635	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E3U36_RS08640	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
E3U36_RS08645	ENOG4105DSJ	YicC domain protein
E3U36_RS08685	ENOG4105CTQ	phosphohexokinase
E3U36_RS08690	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E3U36_RS08695	ENOG4105E98	transcriptional regulator DeoR family
E3U36_RS08700	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
E3U36_RS08705	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
E3U36_RS08715	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
E3U36_RS08720	ENOG4105MJ2	Competence protein
E3U36_RS08725	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E3U36_RS08730	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
E3U36_RS08735	ENOG4105CE1	Ferrous iron transport protein b
E3U36_RS08740	ENOG4105XFK	Ferrous iron transport protein A
E3U36_RS08755	ENOG4105BZM	domain protein
E3U36_RS08760	ENOG4108RRZ	Transcription elongation factor GreB
E3U36_RS08770	ENOG4105E0F	Histidine kinase
E3U36_RS08780	ENOG4105C8U	phosphate abc transporter
E3U36_RS08800	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E3U36_RS08805	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E3U36_RS08825	ENOG4105DRP	amino acid AbC transporter
E3U36_RS08830	ENOG4105C7N	Xanthine uracil vitamin C permease
E3U36_RS08835	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
E3U36_RS08845	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
E3U36_RS08850	ENOG4105D4P	Coproporphyrinogen iii oxidase
E3U36_RS08880	ENOG4105EN6	Membrane
E3U36_RS08885	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
E3U36_RS08890	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
E3U36_RS08905	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E3U36_RS08910	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E3U36_RS08915	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E3U36_RS08920	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
E3U36_RS08925	ENOG4105CB5	ATP-dependent DNA helicase recG
E3U36_RS08930	ENOG4105D6U	Sodium Glutamate Symporter
E3U36_RS08960	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
E3U36_RS08970	ENOG4108RR8	protoporphyrinogen oxidase
E3U36_RS08975	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E3U36_RS09010	ENOG4105D7Z	glutathione synthase
E3U36_RS09015	ENOG4108UJU	UPF0301 protein
E3U36_RS09030	ENOG4105II7	pyrroline-5-carboxylate reductase
E3U36_RS09035	ENOG4108VIA	integral membrane protein
E3U36_RS09040	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E3U36_RS09045	ENOG4105CSA	Coproporphyrinogen iii oxidase
E3U36_RS09070	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
E3U36_RS09075	ENOG4105C5H	ABC transporter
E3U36_RS09080	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
E3U36_RS09100	ENOG4105DNZ	Alpha Beta Hydrolase
E3U36_RS09110	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
E3U36_RS09150	ENOG4105QNJ	serralysin (EC 3.4.24.40)
E3U36_RS09155	ENOG4108HMX	isocitrate dehydrogenase (NADP)
E3U36_RS09160	ENOG4108R99	pseudouridine synthase
E3U36_RS09170	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E3U36_RS09175	ENOG41075W9	High frequency lysogenization protein HflD homolog
E3U36_RS09180	ENOG4107QTF	adenylosuccinate lyase
E3U36_RS09190	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3U36_RS09215	ENOG4105D60	lipoprotein releasing system transmembrane protein
E3U36_RS09220	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E3U36_RS09225	ENOG4105D60	lipoprotein releasing system transmembrane protein
E3U36_RS09235	ENOG4105CEP	NADH dehydrogenase
E3U36_RS09270	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E3U36_RS09285	ENOG4105C4K	Nad synthetase
E3U36_RS09290	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3U36_RS09295	ENOG4108SKK	alpha helix protein
E3U36_RS09300	ENOG4107WP9	Histidine kinase
E3U36_RS09310	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E3U36_RS09315	ENOG4108Z6B	deaminase
E3U36_RS09325	ENOG4108I6E	Sulfatase
E3U36_RS09335	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
E3U36_RS09345	ENOG4105KB2	stringent starvation protein b
E3U36_RS09350	ENOG4107MKT	Stringent starvation protein a
E3U36_RS09355	ENOG4108UJD	30S ribosomal protein S9
E3U36_RS09360	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E3U36_RS09370	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
E3U36_RS09375	ENOG4105C0H	protease
E3U36_RS09380	ENOG4105C0H	protease
E3U36_RS09385	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E3U36_RS09390	ENOG4105VFK	BolA family
E3U36_RS09400	ENOG4105E3I	toluene tolerance
E3U36_RS09405	ENOG4107PE3	Mammalian cell entry related domain protein
E3U36_RS09410	ENOG4105CY3	ABC transporter, permease
E3U36_RS09415	ENOG4105DHJ	ABC, transporter
E3U36_RS09420	ENOG4105C2X	Arabinose 5-phosphate isomerase
E3U36_RS09425	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
E3U36_RS09430	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
E3U36_RS09435	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
E3U36_RS09440	ENOG4108IUZ	ABC transporter
E3U36_RS09445	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3U36_RS09450	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
E3U36_RS09455	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
E3U36_RS09460	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E3U36_RS09465	ENOG41080Z8	PHOSPHOCARRIER protein
E3U36_RS09475	ENOG4105N42	UPF0307 protein
E3U36_RS09500	ENOG4105QD6	exported protein
E3U36_RS09505	ENOG4105C03	ribonuclease
E3U36_RS09510	ENOG4108Z03	MAF-like protein
E3U36_RS09515	ENOG4105VQ7	Rod shape-determining protein MreD
E3U36_RS09520	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E3U36_RS09540	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E3U36_RS09545	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E3U36_RS09550	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E3U36_RS09555	ENOG4105RG0	Membrane
E3U36_RS09560	ENOG4108IA2	Sodium pantothenate symporter
E3U36_RS09565	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E3U36_RS09590	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
E3U36_RS09595	ENOG4105CAK	Cell division ATP-binding protein ftsE
E3U36_RS09600	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E3U36_RS09605	ENOG4106H78	methyltransferase
E3U36_RS09610	ENOG4105MG3	Membrane
E3U36_RS09620	ENOG4107FS9	Membrane
E3U36_RS09630	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E3U36_RS09635	ENOG4105EX9	Membrane
E3U36_RS09685	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E3U36_RS09700	ENOG4105RQF	LysR family Transcriptional regulator
E3U36_RS09715	ENOG4105IPI	Membrane
E3U36_RS09730	ENOG4108Z4V	iron-sulfur cluster assembly
E3U36_RS09735	ENOG4105DIW	FeS assembly protein SUFB
E3U36_RS09740	ENOG4105C3K	feS assembly ATPase SufC
E3U36_RS09745	ENOG4105JRK	feS assembly protein SufD
E3U36_RS09750	ENOG4105C9B	Cysteine desulfurase
E3U36_RS09755	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
E3U36_RS09760	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E3U36_RS09765	ENOG4105KMX	major outer membrane lipoprotein
E3U36_RS09770	ENOG4105CA9	Pyruvate kinase
E3U36_RS09790	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E3U36_RS09800	ENOG4105DR5	peptidase
E3U36_RS09805	ENOG4105NXV	High-affinity zinc uptake system protein
E3U36_RS09810	ENOG4105FDK	ABC transporter
E3U36_RS09815	ENOG4105FAV	ABC, transporter
E3U36_RS09820	ENOG4108T1M	outer membrane protein x
E3U36_RS09830	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
E3U36_RS09835	ENOG4107QMS	site-determining protein
E3U36_RS09840	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
E3U36_RS09845	ENOG4105VNG	YcgL domain-containing protein
E3U36_RS09860	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
E3U36_RS09865	ENOG4108ZZ3	UPF0260 protein
E3U36_RS09885	ENOG4107H52	Dicarboxylate transport
E3U36_RS09895	ENOG4107H52	Dicarboxylate transport
E3U36_RS09905	ENOG4105WXT	Conserved Protein
E3U36_RS09925	ENOG4105CW0	outer membrane usher protein
E3U36_RS09935	ENOG4105C5D	exported protein
E3U36_RS09955	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
E3U36_RS09995	ENOG4105D3R	alkyl hydroperoxide reductase
E3U36_RS10035	ENOG4105EJQ	L-serine dehydratase
E3U36_RS10040	ENOG4105C44	Serine transporter
E3U36_RS10050	ENOG4105EGS	Mechanosensitive ion channel
E3U36_RS10055	ENOG41090EX	DsrE family
E3U36_RS10060	ENOG4107XI7	Tetr family transcriptional regulator
E3U36_RS10065	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E3U36_RS10070	ENOG4105BZS	acriflavin resistance protein
E3U36_RS10095	ENOG4105KF5	hemolysin expression-modulating protein
E3U36_RS10110	ENOG4105EIN	peptidylprolyl cis-trans isomerase
E3U36_RS10120	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E3U36_RS10125	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E3U36_RS10130	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E3U36_RS10135	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E3U36_RS10140	ENOG4105M85	Bola protein
E3U36_RS10165	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E3U36_RS10170	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E3U36_RS10190	ENOG4105C6K	Malic enzyme
E3U36_RS10205	ENOG4105CX6	glutaminyL-tRNA synthetase
E3U36_RS10210	ENOG4105CI1	PTS System
E3U36_RS10220	ENOG4108RW8	Universal stress protein F
E3U36_RS10255	ENOG4105K5X	acetyltransferase
E3U36_RS10265	ENOG4106V6P	Exoenzyme S synthesis protein C
E3U36_RS10295	ENOG4105VZF	DsrB protein
E3U36_RS10315	ENOG4105EKE	dihydroorotase
E3U36_RS10325	ENOG4106AH0	Glycosyl Transferase
E3U36_RS10340	ENOG4105ECY	inositol monophosphatase
E3U36_RS10345	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
E3U36_RS10350	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E3U36_RS10360	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
E3U36_RS10365	ENOG4108Z4V	iron-sulfur cluster assembly
E3U36_RS10390	ENOG4105VJY	transcriptional regulator
E3U36_RS10400	ENOG4105DNE	Transposase
E3U36_RS10435	ENOG4105CI3	gtp-binding protein typa
E3U36_RS10450	ENOG4107QPK	)-transporter
E3U36_RS10460	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
E3U36_RS10465	ENOG4105EE5	Membrane protein terC
E3U36_RS10470	ENOG4108GAE	asmA family
E3U36_RS10475	ENOG4105DHP	deoxycytidine triphosphate deaminase
E3U36_RS10485	ENOG4105D1F	ATP-binding protein
E3U36_RS10490	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E3U36_RS10495	ENOG4105VAW	lrga family
E3U36_RS10500	ENOG41067MG	lrgb family
E3U36_RS10505	ENOG4107GZ4	SanA protein
E3U36_RS10510	ENOG4105DHF	Membrane
E3U36_RS10515	ENOG4105DHF	Membrane
E3U36_RS10530	ENOG4105EUJ	GTP cyclohydrolase i
E3U36_RS10545	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E3U36_RS10550	ENOG4105D06	uba thif-type nad fad binding protein
E3U36_RS10575	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
E3U36_RS10580	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E3U36_RS10590	ENOG4105KHC	sulfurtransferase
E3U36_RS10595	ENOG4105Y3U	Transglycosylase-associated protein
E3U36_RS10630	ENOG4105HFZ	Membrane
E3U36_RS10645	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E3U36_RS10655	ENOG4105CHW	UPF0052 protein
E3U36_RS10660	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E3U36_RS10690	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
E3U36_RS10710	ENOG4105DUX	Transporter
E3U36_RS10740	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E3U36_RS10745	ENOG4108MK9	spermidine N(1)-acetyltransferase
E3U36_RS10750	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
E3U36_RS10755	ENOG4105C9X	ppx gppa phosphatase
E3U36_RS10760	ENOG4105CJW	magnesium transporter
E3U36_RS10775	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E3U36_RS10780	ENOG4105W4M	Transport-associated protein
E3U36_RS10795	ENOG4107835	probably involved in intracellular septation (By similarity)
E3U36_RS10800	ENOG4105NAU	thioesterase Superfamily protein
E3U36_RS10805	ENOG410822N	TonB family
E3U36_RS10820	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E3U36_RS10830	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
E3U36_RS10865	ENOG4105I93	response regulator
E3U36_RS10870	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E3U36_RS10900	ENOG4107104	thymidine kinase
E3U36_RS10915	ENOG4105CIY	formyltetrahydrofolate deformylase
E3U36_RS10935	ENOG4105CGK	Exodeoxyribonuclease III
E3U36_RS10940	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E3U36_RS10950	ENOG41069NU	Nitroreductase
E3U36_RS10955	ENOG4105D07	Signal peptide peptidase, SppA
E3U36_RS10965	ENOG4105VUT	cytoplasmic protein
E3U36_RS10970	ENOG4105E0X	reductase
E3U36_RS10985	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
E3U36_RS11025	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E3U36_RS11035	ENOG4106K28	UPF0283 membrane protein
E3U36_RS11045	ENOG4105FM1	phage shock protein C
E3U36_RS11050	ENOG4105YYT	phage shock protein B
E3U36_RS11065	ENOG41087YS	Phage shock protein A
E3U36_RS11075	ENOG4108HIY	periplasmic
E3U36_RS11080	ENOG4108I5W	peptide transport system, permease protein
E3U36_RS11085	ENOG4108EU3	peptide transport system, permease
E3U36_RS11090	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
E3U36_RS11095	ENOG4108JQ2	peptide transport system atp-binding protein
E3U36_RS11100	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E3U36_RS11135	ENOG4107XU6	Glycosyl transferase (Group 1
E3U36_RS11165	ENOG4105D1S	lipid A biosynthesis
E3U36_RS11185	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E3U36_RS11190	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E3U36_RS11200	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E3U36_RS11205	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E3U36_RS11210	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E3U36_RS11220	ENOG4106428	Protein of unknown function (DUF2496)
E3U36_RS11235	ENOG4108ZZF	transport protein (ExbD)
E3U36_RS11250	ENOG4108K81	inner membrane protein YghB
E3U36_RS11255	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E3U36_RS11260	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E3U36_RS11265	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E3U36_RS11275	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E3U36_RS11280	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E3U36_RS11285	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E3U36_RS11290	ENOG4105DTN	riboflavin biosynthesis protein ribF
E3U36_RS11295	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
E3U36_RS11310	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E3U36_RS11345	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E3U36_RS11355	ENOG4108Z5K	methylglyoxal synthase
E3U36_RS11365	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
E3U36_RS11370	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
E3U36_RS11375	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
E3U36_RS11405	ENOG4105NNH	LexA regulated protein
E3U36_RS11410	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
E3U36_RS11415	ENOG41090R7	Ferric uptake
E3U36_RS11440	ENOG4105CS0	peptidase
E3U36_RS11445	ENOG4107H3J	ribonuclease
E3U36_RS11480	ENOG4108NE3	Salt-induced outer membrane protein
E3U36_RS11515	ENOG4108M6U	Universal stress protein A
E3U36_RS11545	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E3U36_RS11550	ENOG4105D0A	hydroxylase
E3U36_RS11555	ENOG4107RAQ	aminopeptidase
E3U36_RS11560	ENOG4105E07	UPF0149 protein
E3U36_RS11565	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
E3U36_RS11590	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E3U36_RS11595	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E3U36_RS11600	ENOG4105DXN	mazG family
E3U36_RS11610	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E3U36_RS11625	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E3U36_RS11630	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E3U36_RS11635	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E3U36_RS11640	ENOG4105BZ4	penicillin-binding protein
E3U36_RS11645	ENOG4105PW4	Sugar fermentation stimulation protein homolog
E3U36_RS11650	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3U36_RS11660	ENOG4105DJ0	Poly(A) Polymerase
E3U36_RS11665	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3U36_RS11685	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
E3U36_RS11690	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
E3U36_RS11695	ENOG4105BZ1	(ABC) transporter
E3U36_RS11700	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E3U36_RS11705	ENOG4105VEQ	Cold shock protein
E3U36_RS11710	ENOG4105W49	UPF0434 protein
E3U36_RS11715	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
E3U36_RS11730	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
E3U36_RS11735	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
E3U36_RS11740	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
E3U36_RS11750	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
E3U36_RS11795	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
E3U36_RS11810	ENOG4105DR9	pseudouridine synthase
E3U36_RS11815	ENOG4108T8E	UPF0325 protein
E3U36_RS11825	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E3U36_RS11830	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E3U36_RS11840	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E3U36_RS11845	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E3U36_RS11850	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E3U36_RS11855	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
E3U36_RS11860	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E3U36_RS11865	ENOG4105KNE	Phosphatidate cytidylyltransferase
E3U36_RS11870	ENOG4105DZP	Membrane-associated zinc metalloprotease
E3U36_RS11875	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3U36_RS11880	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
E3U36_RS11885	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3U36_RS11890	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E3U36_RS11895	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3U36_RS11900	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E3U36_RS11905	ENOG4105C0B	DNA polymerase III (alpha subunit)
E3U36_RS11910	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E3U36_RS11915	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E3U36_RS11920	ENOG4105M1T	rho-binding antiterminator
E3U36_RS11925	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
E3U36_RS11930	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E3U36_RS11935	ENOG4108R96	Methyltransferase, YaeB family
E3U36_RS11950	ENOG4108UMI	ABC transporter, permease
E3U36_RS11955	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E3U36_RS11960	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E3U36_RS11995	ENOG4108ETY	sodium dicarboxylate symporter
E3U36_RS12000	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
E3U36_RS12005	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
E3U36_RS12010	ENOG4107PN8	YfeABCD locus regulator
E3U36_RS12025	ENOG4105CC5	ABC transporter
E3U36_RS12040	ENOG4105DSE	periplasmic solute binding protein
E3U36_RS12050	ENOG4105C22	threonyL-tRNA synthetase
E3U36_RS12055	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
E3U36_RS12060	ENOG41082NX	50s ribosomal protein l35
E3U36_RS12065	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E3U36_RS12075	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E3U36_RS12080	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E3U36_RS12085	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E3U36_RS12090	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E3U36_RS12095	ENOG4105CKK	Glycosyl transferase, family 2
E3U36_RS12100	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E3U36_RS12105	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E3U36_RS12110	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E3U36_RS12115	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
E3U36_RS12120	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
E3U36_RS12125	ENOG4108QBX	(LipO)protein
E3U36_RS12280	ENOG4108ZNX	Heat shock protein
E3U36_RS12290	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
E3U36_RS12300	ENOG4105VEQ	Cold shock protein
