locus-tag	class	description
E3U36_RS00015	COG4811	Protein of unknown function (DUF986)
E3U36_RS00020	COG3716	PTS system mannose fructose sorbose family IID component
E3U36_RS00025	COG3715	PTS system
E3U36_RS00030	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3U36_RS00030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E3U36_RS00040	COG0583	DNA-binding transcription factor activity
E3U36_RS00050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E3U36_RS00055	COG0616	signal peptide processing
E3U36_RS00060	COG1028	Short-chain dehydrogenase reductase Sdr
E3U36_RS00080	COG0009	L-threonylcarbamoyladenylate synthase
E3U36_RS00085	COG0613	PHP domain protein
E3U36_RS00095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3U36_RS00095	COG0512	Glutamine amidotransferase of anthranilate synthase
E3U36_RS00100	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E3U36_RS00100	COG0512	Glutamine amidotransferase of anthranilate synthase
E3U36_RS00150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E3U36_RS00180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3U36_RS00185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E3U36_RS00190	COG1702	phosphate starvation-inducible protein PhoH
E3U36_RS00195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
E3U36_RS00200	COG4535	Mg2 and Co2 transporter CorC
E3U36_RS00205	COG0815	Transfers the fatty acyl group on membrane lipoproteins
E3U36_RS00215	COG0495	leucyl-tRNA aminoacylation
E3U36_RS00220	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
E3U36_RS00225	COG1466	dna polymerase III delta subunit
E3U36_RS00235	COG0799	negative regulation of ribosome biogenesis
E3U36_RS00240	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
E3U36_RS00245	COG0768	penicillin binding
E3U36_RS00250	COG0772	Belongs to the SEDS family
E3U36_RS00255	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E3U36_RS00260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E3U36_RS00265	COG1686	Belongs to the peptidase S11 family
E3U36_RS00270	COG2921	Belongs to the UPF0250 family
E3U36_RS00275	COG0321	lipoyl(octanoyl) transferase activity
E3U36_RS00280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
E3U36_RS00295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E3U36_RS00305	COG1780	Probably involved in ribonucleotide reductase function
E3U36_RS00315	COG1780	Probably involved in ribonucleotide reductase function
E3U36_RS00330	COG4175	Glycine betaine
E3U36_RS00335	COG4176	ABC-type proline glycine betaine transport system permease component
E3U36_RS00340	COG2113	Glycine betaine
E3U36_RS00360	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
E3U36_RS00360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E3U36_RS00365	COG2960	long-chain fatty acid transporting porin activity
E3U36_RS00380	COG1609	Transcriptional regulator
E3U36_RS00390	COG0275	rRNA processing
E3U36_RS00395	COG3116	cell division
E3U36_RS00400	COG0768	penicillin binding
E3U36_RS00405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E3U36_RS00410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E3U36_RS00415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3U36_RS00420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E3U36_RS00425	COG0772	Belongs to the SEDS family
E3U36_RS00430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
E3U36_RS00435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E3U36_RS00440	COG1181	Belongs to the D-alanine--D-alanine ligase family
E3U36_RS00445	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E3U36_RS00450	COG0849	cell division
E3U36_RS00455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E3U36_RS00460	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
E3U36_RS00475	COG0653	protein targeting
E3U36_RS00480	COG0494	nUDIX hydrolase
E3U36_RS00485	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
E3U36_RS00490	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
E3U36_RS00495	COG0237	dephospho-CoA kinase activity
E3U36_RS00530	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
E3U36_RS00535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E3U36_RS00540	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E3U36_RS00565	COG2918	glutathione biosynthetic process
E3U36_RS00590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3U36_RS00600	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
E3U36_RS00610	COG0335	large ribosomal subunit rRNA binding
E3U36_RS00620	COG0287	Prephenate dehydrogenase
E3U36_RS00620	COG1605	Chorismate mutase
E3U36_RS00635	COG0596	Alpha beta hydrolase
E3U36_RS00650	COG0814	amino acid
E3U36_RS00655	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
E3U36_RS00660	COG2855	membrane
E3U36_RS00670	COG0833	amino acid
E3U36_RS00680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3U36_RS00710	COG0531	amino acid
E3U36_RS00715	COG2925	Exonuclease
E3U36_RS00760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E3U36_RS00770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
E3U36_RS00775	COG1381	Involved in DNA repair and RecF pathway recombination
E3U36_RS00780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
E3U36_RS00785	COG0571	ribonuclease III activity
E3U36_RS00800	COG3086	response to oxidative stress
E3U36_RS00805	COG3026	antisigma factor binding
E3U36_RS00815	COG1595	DNA-templated transcription, initiation
E3U36_RS00835	COG0513	Belongs to the DEAD box helicase family
E3U36_RS00845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
E3U36_RS00850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E3U36_RS00855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
E3U36_RS00865	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3U36_RS00870	COG2914	Belongs to the UPF0125 (RnfH) family
E3U36_RS00875	COG2867	negative regulation of translational initiation
E3U36_RS00880	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
E3U36_RS00900	COG3311	Transcriptional regulator
E3U36_RS00960	COG3596	GTP binding
E3U36_RS00965	COG2378	regulation of single-species biofilm formation
E3U36_RS00985	COG2003	Belongs to the UPF0758 family
E3U36_RS01035	COG0751	glycine-tRNA ligase activity
E3U36_RS01065	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
E3U36_RS01080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E3U36_RS01085	COG0546	phosphoglycolate phosphatase activity
E3U36_RS01090	COG0180	Tryptophanyl-tRNA synthetase
E3U36_RS01105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E3U36_RS01115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E3U36_RS01120	COG0009	L-threonylcarbamoyladenylate synthase
E3U36_RS01135	COG2989	Protein conserved in bacteria
E3U36_RS01140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3U36_RS01150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E3U36_RS01155	COG0017	Asparaginyl-tRNA synthetase
E3U36_RS01160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E3U36_RS01170	COG0167	dihydroorotate dehydrogenase activity
E3U36_RS01190	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
E3U36_RS01200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E3U36_RS01220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E3U36_RS01230	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
E3U36_RS01235	COG1575	Belongs to the MenA family. Type 1 subfamily
E3U36_RS01250	COG3074	FtsZ-dependent cytokinesis
E3U36_RS01270	COG1442	glycosyl transferase family 8
E3U36_RS01275	COG0515	serine threonine protein kinase
E3U36_RS01280	COG0438	transferase activity, transferring glycosyl groups
E3U36_RS01310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3U36_RS01325	COG0218	Necessary for normal cell division and for the maintenance of normal septation
E3U36_RS01335	COG1194	a g-specific adenine glycosylase
E3U36_RS01340	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
E3U36_RS01345	COG0741	lytic transglycosylase activity
E3U36_RS01390	COG0318	PFAM AMP-dependent synthetase and ligase
E3U36_RS01415	COG2076	Multidrug Resistance protein
E3U36_RS01420	COG2076	Multidrug Resistance protein
E3U36_RS01425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E3U36_RS01430	COG1737	Transcriptional regulator
E3U36_RS01440	COG1737	Transcriptional regulator
E3U36_RS01455	COG0561	phosphatase activity
E3U36_RS01460	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E3U36_RS01515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E3U36_RS01520	COG0322	excinuclease ABC activity
E3U36_RS01525	COG2197	response regulator
E3U36_RS01555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E3U36_RS01560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3U36_RS01565	COG0346	lactoylglutathione lyase activity
E3U36_RS01590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
E3U36_RS01595	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
E3U36_RS01605	COG3422	double-strand break repair
E3U36_RS01610	COG0484	heat shock protein binding
E3U36_RS01615	COG0443	Heat shock 70 kDa protein
E3U36_RS01620	COG1584	GPR1 FUN34 yaaH family protein
E3U36_RS01625	COG0521	Mo-molybdopterin cofactor biosynthetic process
E3U36_RS01630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E3U36_RS01635	COG3022	response to hydroperoxide
E3U36_RS01665	COG3045	CreA protein
E3U36_RS01670	COG2207	Transcriptional regulator
E3U36_RS01670	COG3708	Transcriptional regulator
E3U36_RS01695	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
E3U36_RS01705	COG0741	lytic transglycosylase activity
E3U36_RS01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
E3U36_RS01745	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
E3U36_RS01750	COG2195	Cleaves the N-terminal amino acid of tripeptides
E3U36_RS01765	COG1815	bacterial-type flagellum-dependent cell motility
E3U36_RS01830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E3U36_RS01845	COG1191	sigma factor activity
E3U36_RS01910	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E3U36_RS01925	COG1987	bacterial-type flagellum assembly
E3U36_RS01940	COG1454	alcohol dehydrogenase
E3U36_RS01945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3U36_RS01965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3U36_RS01970	COG0564	pseudouridine synthase activity
E3U36_RS01980	COG0542	response to heat
E3U36_RS02010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
E3U36_RS02020	COG1072	(Pantothenic acid kinase))
E3U36_RS02045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E3U36_RS02055	COG0250	Participates in transcription elongation, termination and antitermination
E3U36_RS02060	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
E3U36_RS02065	COG0081	regulation of translation
E3U36_RS02070	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
E3U36_RS02075	COG0222	ribosome binding
E3U36_RS02080	COG0085	RNA polymerase activity
E3U36_RS02085	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E3U36_RS02100	COG2022	thiamine diphosphate biosynthetic process
E3U36_RS02115	COG0352	thiamine-phosphate diphosphorylase activity
E3U36_RS02125	COG2816	NAD+ diphosphatase activity
E3U36_RS02155	COG0745	RESPONSE REGULATOR receiver
E3U36_RS02165	COG1114	Component of the transport system for branched-chain amino acids
E3U36_RS02170	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
E3U36_RS02175	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E3U36_RS02180	COG0343	queuine tRNA-ribosyltransferase activity
E3U36_RS02185	COG1862	Preprotein translocase
E3U36_RS02195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E3U36_RS02200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
E3U36_RS02205	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3U36_RS02205	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E3U36_RS02210	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
E3U36_RS02215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3U36_RS02220	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E3U36_RS02225	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E3U36_RS02230	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E3U36_RS02235	COG0142	geranyltranstransferase activity
E3U36_RS02245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3U36_RS02245	COG0301	tRNA thio-modification
E3U36_RS02255	COG1666	GTP binding
E3U36_RS02265	COG0109	protoheme IX farnesyltransferase activity
E3U36_RS02270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E3U36_RS02275	COG1845	cytochrome c oxidase, subunit III
E3U36_RS02280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E3U36_RS02285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E3U36_RS02310	COG0033	Phosphoglucomutase
E3U36_RS02315	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
E3U36_RS02325	COG3171	Protein conserved in bacteria
E3U36_RS02330	COG0220	tRNA (guanine-N7-)-methyltransferase activity
E3U36_RS02355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E3U36_RS02365	COG0758	DNA mediated transformation
E3U36_RS02375	COG0242	peptide deformylase activity
E3U36_RS02380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E3U36_RS02385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E3U36_RS02385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E3U36_RS02395	COG1970	mechanosensitive ion channel activity
E3U36_RS02400	COG3036	rescue of stalled ribosome
E3U36_RS02405	COG0789	Transcriptional regulator
E3U36_RS02410	COG0203	ribosomal protein L17
E3U36_RS02420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
E3U36_RS02430	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E3U36_RS02435	COG0257	Belongs to the bacterial ribosomal protein bL36 family
E3U36_RS02440	COG0201	protein transport
E3U36_RS02445	COG0200	Binds to the 23S rRNA
E3U36_RS02450	COG1841	ribosomal large subunit assembly
E3U36_RS02455	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
E3U36_RS02460	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
E3U36_RS02465	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
E3U36_RS02470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
E3U36_RS02475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
E3U36_RS02480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E3U36_RS02490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
E3U36_RS02495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
E3U36_RS02505	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
E3U36_RS02520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E3U36_RS02525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E3U36_RS02530	COG0089	rRNA binding
E3U36_RS02535	COG0088	Forms part of the polypeptide exit tunnel
E3U36_RS02540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
E3U36_RS02545	COG0051	transcription antitermination factor activity, RNA binding
E3U36_RS02560	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E3U36_RS02565	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
E3U36_RS02570	COG0049	tRNA binding
E3U36_RS02575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
E3U36_RS02585	COG2923	Belongs to the DsrF TusC family
E3U36_RS02590	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E3U36_RS02595	COG2964	Protein conserved in bacteria
E3U36_RS02600	COG0545	Peptidyl-prolyl cis-trans isomerase
E3U36_RS02720	COG3772	lysozyme
E3U36_RS02755	COG1484	DNA-dependent DNA replication
E3U36_RS02860	COG3023	N-Acetylmuramoyl-L-alanine amidase
E3U36_RS02895	COG1124	(ABC) transporter
E3U36_RS02910	COG2974	May be involved in recombination
E3U36_RS02960	COG3530	Putative quorum-sensing-regulated virulence factor
E3U36_RS02975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3U36_RS02980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E3U36_RS02985	COG3115	cell septum assembly
E3U36_RS02995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E3U36_RS03000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3U36_RS03005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E3U36_RS03010	COG2190	(PTS) system
E3U36_RS03030	COG0408	coproporphyrinogen oxidase activity
E3U36_RS03035	COG1160	GTP binding
E3U36_RS03040	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3U36_RS03045	COG2976	Protein conserved in bacteria
E3U36_RS03050	COG0124	histidyl-tRNA synthetase
E3U36_RS03055	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
E3U36_RS03075	COG0105	UTP biosynthetic process
E3U36_RS03090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E3U36_RS03095	COG2975	iron-sulfur cluster assembly
E3U36_RS03100	COG0633	Ferredoxin
E3U36_RS03110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
E3U36_RS03120	COG4991	sh3 domain protein
E3U36_RS03130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E3U36_RS03135	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
E3U36_RS03140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
E3U36_RS03150	COG0358	DNA primase activity
E3U36_RS03170	COG0501	Belongs to the peptidase M48B family
E3U36_RS03195	COG2966	Psort location CytoplasmicMembrane, score
E3U36_RS03200	COG3610	response to peptide
E3U36_RS03215	COG2356	endonuclease I
E3U36_RS03235	COG0012	GTP binding
E3U36_RS03250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E3U36_RS03255	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
E3U36_RS03260	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
E3U36_RS03265	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
E3U36_RS03270	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
E3U36_RS03275	COG2890	protein-(glutamine-N5) methyltransferase activity
E3U36_RS03280	COG2912	Transglutaminase-like superfamily
E3U36_RS03285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
E3U36_RS03290	COG1242	4 iron, 4 sulfur cluster binding
E3U36_RS03300	COG3381	protein complex oligomerization
E3U36_RS03350	COG0534	Mate efflux family protein
E3U36_RS03355	COG0307	riboflavin synthase, alpha
E3U36_RS03380	COG0583	DNA-binding transcription factor activity
E3U36_RS03385	COG1609	Transcriptional regulator
E3U36_RS03390	COG0018	arginyl-trna synthetase
E3U36_RS03400	COG0500	methyltransferase
E3U36_RS03405	COG2226	methyltransferase
E3U36_RS03410	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E3U36_RS03415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
E3U36_RS03420	COG0494	nUDIX hydrolase
E3U36_RS03425	COG0217	transcriptional regulatory protein
E3U36_RS03430	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
E3U36_RS03435	COG0632	four-way junction helicase activity
E3U36_RS03440	COG2255	four-way junction helicase activity
E3U36_RS03460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E3U36_RS03475	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E3U36_RS03490	COG0567	Dehydrogenase, E1 component
E3U36_RS03495	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3U36_RS03505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E3U36_RS03510	COG1271	oxidase subunit
E3U36_RS03515	COG1294	oxidase, subunit
E3U36_RS03520	COG4890	Cyd operon protein YbgT
E3U36_RS03535	COG0811	peptide transport
E3U36_RS03540	COG0848	biopolymer transport protein
E3U36_RS03545	COG3064	Membrane
E3U36_RS03550	COG0823	Involved in the tonB-independent uptake of proteins
E3U36_RS03555	COG2885	chlorophyll binding
E3U36_RS03560	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E3U36_RS03575	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
E3U36_RS03595	COG0588	phosphoglycerate mutase activity
E3U36_RS03625	COG2823	Periplasmic or secreted lipoprotein
E3U36_RS03630	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
E3U36_RS03635	COG0792	nuclease activity
E3U36_RS03645	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E3U36_RS03710	COG2259	Doxx family
E3U36_RS03730	COG0586	Pfam SNARE associated Golgi protein
E3U36_RS03735	COG0861	Integral membrane protein TerC family
E3U36_RS03750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
E3U36_RS03790	COG0215	cysteine-tRNA ligase activity
E3U36_RS03795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E3U36_RS03800	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E3U36_RS03820	COG0300	oxidoreductase activity
E3U36_RS03825	COG3118	belongs to the thioredoxin family
E3U36_RS03845	COG2217	Heavy metal translocating P-type atpase
E3U36_RS03850	COG3735	TraB family
E3U36_RS03870	COG4232	protein-disulfide reductase activity
E3U36_RS03875	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E3U36_RS03885	COG3030	protein affecting phage T7 exclusion by the F plasmid
E3U36_RS03890	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
E3U36_RS03895	COG0459	protein refolding
E3U36_RS03910	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
E3U36_RS03950	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
E3U36_RS03955	COG0706	membrane insertase activity
E3U36_RS03960	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
E3U36_RS03965	COG0594	ribonuclease P activity
E3U36_RS03970	COG0230	Belongs to the bacterial ribosomal protein bL34 family
E3U36_RS03975	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
E3U36_RS03980	COG0592	DNA-directed DNA polymerase activity
E3U36_RS03990	COG0187	DNA topoisomerase II activity
E3U36_RS03995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E3U36_RS04005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E3U36_RS04010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
E3U36_RS04015	COG0355	proton-transporting ATP synthase activity, rotational mechanism
E3U36_RS04020	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
E3U36_RS04030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
E3U36_RS04035	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E3U36_RS04040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
E3U36_RS04050	COG0356	it plays a direct role in the translocation of protons across the membrane
E3U36_RS04055	COG3312	ion transport
E3U36_RS04080	COG0445	tRNA wobble uridine modification
E3U36_RS04085	COG0716	FMN binding
E3U36_RS04090	COG1522	sequence-specific DNA binding
E3U36_RS04095	COG2502	aspartate--ammonia ligase
E3U36_RS04140	COG0583	DNA-binding transcription factor activity
E3U36_RS04145	COG3085	chromosome segregation
E3U36_RS04165	COG0028	Belongs to the TPP enzyme family
E3U36_RS04190	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
E3U36_RS04205	COG0210	DNA helicase
E3U36_RS04210	COG0248	Ppx GppA phosphatase
E3U36_RS04215	COG0513	Belongs to the DEAD box helicase family
E3U36_RS04220	COG3118	belongs to the thioredoxin family
E3U36_RS04230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E3U36_RS04240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E3U36_RS04245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E3U36_RS04250	COG1088	dTDP-glucose 4,6-dehydratase activity
E3U36_RS04255	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E3U36_RS04260	COG0456	acetyltransferase
E3U36_RS04265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E3U36_RS04270	COG2244	polysaccharide biosynthetic process
E3U36_RS04275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
E3U36_RS04285	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
E3U36_RS04315	COG3071	HemY protein
E3U36_RS04320	COG2959	enzyme of heme biosynthesis
E3U36_RS04325	COG1587	Uroporphyrinogen-III synthase
E3U36_RS04330	COG0181	hydroxymethylbilane synthase activity
E3U36_RS04340	COG1965	Belongs to the frataxin family
E3U36_RS04350	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
E3U36_RS04355	COG3159	Protein conserved in bacteria
E3U36_RS04365	COG1011	Hydrolase
E3U36_RS04370	COG0210	DNA helicase
E3U36_RS04385	COG0598	Magnesium transport protein CorA
E3U36_RS04395	COG0514	ATP-dependent DNA helicase (RecQ)
E3U36_RS04410	COG2267	carboxylic ester hydrolase activity
E3U36_RS04415	COG0561	phosphatase activity
E3U36_RS04425	COG3121	Chaperone
E3U36_RS04430	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E3U36_RS04445	COG0149	triose-phosphate isomerase activity
E3U36_RS04465	COG2814	Major facilitator Superfamily
E3U36_RS04495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E3U36_RS04500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
E3U36_RS04505	COG1519	Transferase
E3U36_RS04515	COG0859	PFAM glycosyl transferase family 9
E3U36_RS04520	COG0859	PFAM glycosyl transferase family 9
E3U36_RS04525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3U36_RS04530	COG2861	carbohydrate metabolic process
E3U36_RS04535	COG4942	peptidase
E3U36_RS04540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3U36_RS04545	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
E3U36_RS04550	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
E3U36_RS04560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E3U36_RS04580	COG2205	protein histidine kinase activity
E3U36_RS04585	COG0745	RESPONSE REGULATOR receiver
E3U36_RS04595	COG3678	ATP-independent chaperone mediated protein folding
E3U36_RS04740	COG1530	ribonuclease E activity
E3U36_RS04745	COG0564	pseudouridine synthase activity
E3U36_RS04750	COG0424	maF-like protein
E3U36_RS04760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
E3U36_RS04765	COG0416	fatty acid biosynthetic process
E3U36_RS04770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E3U36_RS04775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
E3U36_RS04780	COG1028	Short-chain dehydrogenase reductase Sdr
E3U36_RS04790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3U36_RS04795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E3U36_RS04800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E3U36_RS04805	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
E3U36_RS04810	COG0470	DNA polymerase III
E3U36_RS04815	COG0084	hydrolase, TatD family'
E3U36_RS04820	COG0537	adenosine 5'-monophosphoramidase activity
E3U36_RS04825	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
E3U36_RS04860	COG3066	DNA modification
E3U36_RS04870	COG0010	Belongs to the arginase family
E3U36_RS04885	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
E3U36_RS04890	COG3091	SprT-like family
E3U36_RS04930	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3U36_RS04940	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E3U36_RS04945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E3U36_RS04955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E3U36_RS04970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3U36_RS04970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3U36_RS04975	COG1105	Belongs to the carbohydrate kinase PfkB family
E3U36_RS04990	COG1715	Restriction endonuclease
E3U36_RS05095	COG0142	geranyltranstransferase activity
E3U36_RS05100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
E3U36_RS05105	COG0211	Belongs to the bacterial ribosomal protein bL27 family
E3U36_RS05110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E3U36_RS05120	COG1534	Rna-binding protein
E3U36_RS05135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E3U36_RS05140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E3U36_RS05145	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E3U36_RS05160	COG0779	Required for maturation of 30S ribosomal subunits
E3U36_RS05165	COG0195	Participates in both transcription termination and antitermination
E3U36_RS05170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
E3U36_RS05175	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
E3U36_RS05180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
E3U36_RS05190	COG1185	polyribonucleotide nucleotidyltransferase activity
E3U36_RS05235	COG0826	peptidase U32
E3U36_RS05250	COG3153	acetyltransferase
E3U36_RS05260	COG3787	Belongs to the UPF0306 family
E3U36_RS05265	COG0602	queuosine metabolic process
E3U36_RS05280	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
E3U36_RS05295	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
E3U36_RS05300	COG0525	valine-tRNA ligase activity
E3U36_RS05305	COG2927	DNA polymerase III (CHI subunit)
E3U36_RS05310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E3U36_RS05315	COG0795	lipopolysaccharide-transporting ATPase activity
E3U36_RS05320	COG0795	lipopolysaccharide-transporting ATPase activity
E3U36_RS05325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E3U36_RS05345	COG3423	Transcriptional regulator
E3U36_RS05355	COG1438	arginine binding
E3U36_RS05375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
E3U36_RS05385	COG4783	chaperone-mediated protein folding
E3U36_RS05390	COG0628	permease
E3U36_RS05395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3U36_RS05420	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E3U36_RS05440	COG2707	UPF0756 membrane protein
E3U36_RS05445	COG1444	tRNA N-acetyltransferase activity
E3U36_RS05465	COG2832	Protein of unknown function (DUF454)
E3U36_RS05470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E3U36_RS05495	COG3188	usher protein
E3U36_RS05505	COG3188	usher protein
E3U36_RS05520	COG0579	oxidoreductase
E3U36_RS05550	COG3683	transport system, periplasmic component
E3U36_RS05565	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
E3U36_RS05575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E3U36_RS05590	COG3034	peptidoglycan biosynthetic process
E3U36_RS05630	COG1477	protein flavinylation
E3U36_RS05635	COG2991	Protein conserved in bacteria
E3U36_RS05650	COG0306	phosphate transporter
E3U36_RS05655	COG2081	HI0933 family
E3U36_RS05670	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
E3U36_RS05675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
E3U36_RS05685	COG0626	cystathionine gamma-synthase activity
E3U36_RS05690	COG1757	Na H antiporter
E3U36_RS05695	COG0113	porphobilinogen synthase activity
E3U36_RS05735	COG1301	dicarboxylic acid transport
E3U36_RS05750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E3U36_RS05755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E3U36_RS05765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E3U36_RS05770	COG0328	RNA-DNA hybrid ribonuclease activity
E3U36_RS05775	COG2226	methyltransferase
E3U36_RS05780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E3U36_RS05785	COG0741	lytic transglycosylase activity
E3U36_RS05785	COG1388	LysM domain
E3U36_RS05795	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
E3U36_RS05810	COG0668	transmembrane transport
E3U36_RS05840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3U36_RS05845	COG0508	dehydrogenase complex catalyzes the overall conversion of
E3U36_RS05850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E3U36_RS05875	COG1448	Aminotransferase
E3U36_RS05895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3U36_RS05945	COG3708	Transcriptional regulator
E3U36_RS05945	COG2207	Transcriptional regulator
E3U36_RS05960	COG1113	amino acid transport
E3U36_RS05990	COG2610	gluconate transmembrane transporter activity
E3U36_RS06000	COG0735	belongs to the Fur family
E3U36_RS06015	COG2937	Belongs to the GPAT DAPAT family
E3U36_RS06020	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
E3U36_RS06030	COG0166	Belongs to the GPI family
E3U36_RS06035	COG0527	aspartate kinase activity
E3U36_RS06060	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E3U36_RS06100	COG0354	folic acid binding
E3U36_RS06140	COG4974	Belongs to the 'phage' integrase family
E3U36_RS06145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E3U36_RS06150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E3U36_RS06160	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E3U36_RS06165	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E3U36_RS06195	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E3U36_RS06210	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E3U36_RS06230	COG0839	Belongs to the complex I subunit 6 family
E3U36_RS06240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E3U36_RS06250	COG1007	ATP synthesis coupled electron transport
E3U36_RS06275	COG1441	menaquinone biosynthetic process
E3U36_RS06295	COG0814	amino acid
E3U36_RS06305	COG0633	Ferredoxin
E3U36_RS06310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3U36_RS06315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E3U36_RS06320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E3U36_RS06330	COG2205	protein histidine kinase activity
E3U36_RS06330	COG0784	Response regulator, receiver
E3U36_RS06345	COG2197	response regulator
E3U36_RS06350	COG0642	Histidine kinase
E3U36_RS06350	COG2198	Histidine kinase
E3U36_RS06370	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
E3U36_RS06375	COG3081	Nucleoid-associated protein
E3U36_RS06385	COG3083	sulfuric ester hydrolase activity
E3U36_RS06435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3U36_RS06460	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
E3U36_RS06465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E3U36_RS06480	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
E3U36_RS06485	COG1956	GAF domain-containing protein
E3U36_RS06520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E3U36_RS06525	COG3140	Belongs to the UPF0181 family
E3U36_RS06555	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
E3U36_RS06565	COG0084	hydrolase, TatD family'
E3U36_RS06570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E3U36_RS06580	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
E3U36_RS06585	COG0813	purine-nucleoside phosphorylase activity
E3U36_RS06605	COG0560	Phosphoserine phosphatase
E3U36_RS06620	COG0488	(ABC) transporter
E3U36_RS06660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3U36_RS06670	COG3210	domain, Protein
E3U36_RS06700	COG3479	Phenolic acid decarboxylase
E3U36_RS06705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E3U36_RS06725	COG1309	transcriptional regulator
E3U36_RS06795	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E3U36_RS06830	COG3120	sequence-specific DNA binding
E3U36_RS06835	COG1067	ATP-dependent peptidase activity
E3U36_RS06840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E3U36_RS06845	COG3009	Protein conserved in bacteria
E3U36_RS06860	COG0488	(ABC) transporter
E3U36_RS06865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E3U36_RS06865	COG0116	Belongs to the methyltransferase superfamily
E3U36_RS06885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
E3U36_RS06895	COG0437	4 iron, 4 sulfur cluster binding
E3U36_RS06900	COG2864	formate dehydrogenase
E3U36_RS06975	COG3188	usher protein
E3U36_RS06990	COG0688	phosphatidylethanolamine metabolic process
E3U36_RS06995	COG1162	GTPase activity
E3U36_RS07000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
E3U36_RS07015	COG0802	atpase or kinase
E3U36_RS07020	COG0860	N-Acetylmuramoyl-L-alanine amidase
E3U36_RS07025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
E3U36_RS07030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
E3U36_RS07035	COG1923	regulation of RNA biosynthetic process
E3U36_RS07040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E3U36_RS07045	COG0330	HflC and HflK could
E3U36_RS07050	COG0330	HflC and HflK could
E3U36_RS07055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
E3U36_RS07060	COG1959	2 iron, 2 sulfur cluster binding
E3U36_RS07065	COG0557	exoribonuclease II activity
E3U36_RS07070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3U36_RS07075	COG0360	Binds together with S18 to 16S ribosomal RNA
E3U36_RS07080	COG2965	DNA replication, synthesis of RNA primer
E3U36_RS07085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E3U36_RS07090	COG0359	binds to the 23S rRNA
E3U36_RS07110	COG3590	peptidase
E3U36_RS07150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3U36_RS07185	COG0019	diaminopimelate decarboxylase activity
E3U36_RS07210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3U36_RS07220	COG1120	ATPase activity
E3U36_RS07290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E3U36_RS07290	COG4651	solute:proton antiporter activity
E3U36_RS07310	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E3U36_RS07320	COG0671	phosphoesterase, PA-phosphatase related
E3U36_RS07350	COG4160	amino acid transport
E3U36_RS07355	COG4215	(ABC) transporter
E3U36_RS07360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E3U36_RS07365	COG1126	abc transporter atp-binding protein
E3U36_RS07395	COG1278	Cold shock
E3U36_RS07400	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
E3U36_RS07405	COG0542	response to heat
E3U36_RS07410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
E3U36_RS07415	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
E3U36_RS07420	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E3U36_RS07430	COG0492	ferredoxin-NADP+ reductase activity
E3U36_RS07440	COG1674	ftsk spoiiie
E3U36_RS07440	COG3107	peptidoglycan biosynthetic process
E3U36_RS07445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
E3U36_RS07450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E3U36_RS07455	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
E3U36_RS07470	COG0252	asparaginase activity
E3U36_RS07475	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
E3U36_RS07480	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
E3U36_RS07485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
E3U36_RS07490	COG0539	negative regulation of cytoplasmic translation
E3U36_RS07495	COG0776	regulation of translation
E3U36_RS07505	COG0842	Transport permease protein
E3U36_RS07510	COG1131	(ABC) transporter
E3U36_RS07540	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
E3U36_RS07545	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
E3U36_RS07565	COG0534	Mate efflux family protein
E3U36_RS07570	COG0523	cobalamin synthesis protein
E3U36_RS07575	COG2879	small protein
E3U36_RS07605	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E3U36_RS07620	COG1388	LysM domain
E3U36_RS07620	COG4942	peptidase
E3U36_RS07625	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
E3U36_RS07630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
E3U36_RS07645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
E3U36_RS07650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
E3U36_RS07680	COG3021	interspecies interaction between organisms
E3U36_RS07715	COG0138	bifunctional purine biosynthesis protein purh
E3U36_RS07735	COG3068	Protein conserved in bacteria
E3U36_RS07740	COG1515	deoxyribonuclease V activity
E3U36_RS07775	COG0114	fumarate hydratase activity
E3U36_RS07785	COG5339	Protein conserved in bacteria
E3U36_RS07805	COG4657	Part of a membrane complex involved in electron transport
E3U36_RS07815	COG4656	Part of a membrane complex involved in electron transport
E3U36_RS07825	COG4659	FMN binding
E3U36_RS07835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E3U36_RS07840	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
E3U36_RS07860	COG0284	orotidine-5'-phosphate decarboxylase activity
E3U36_RS07865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E3U36_RS07870	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E3U36_RS07875	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E3U36_RS07890	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
E3U36_RS07895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E3U36_RS07930	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E3U36_RS07945	COG0805	protein transport
E3U36_RS07950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E3U36_RS07970	COG2226	methyltransferase
E3U36_RS07975	COG1322	Protein conserved in bacteria
E3U36_RS07980	COG0586	Pfam SNARE associated Golgi protein
E3U36_RS08030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E3U36_RS08030	COG2226	methyltransferase
E3U36_RS08030	COG3433	isochorismatase activity
E3U36_RS08070	COG0742	ribosomal rna small subunit methyltransferase
E3U36_RS08130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E3U36_RS08145	COG0583	DNA-binding transcription factor activity
E3U36_RS08175	COG3092	negative regulation of chromosome organization
E3U36_RS08180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E3U36_RS08185	COG0280	phosphate acetyltransferase
E3U36_RS08185	COG0857	belongs to the CobB CobQ family
E3U36_RS08250	COG3691	Protein conserved in bacteria
E3U36_RS08255	COG0183	Belongs to the thiolase family
E3U36_RS08260	COG1024	Enoyl-CoA hydratase
E3U36_RS08260	COG1250	3-hydroxyacyl-CoA dehydrogenase
E3U36_RS08270	COG2840	Smr protein MutS2
E3U36_RS08285	COG3101	peptidyl-lysine hydroxylation
E3U36_RS08305	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
E3U36_RS08305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E3U36_RS08315	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
E3U36_RS08315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E3U36_RS08320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E3U36_RS08330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E3U36_RS08340	COG0101	tRNA pseudouridine synthase activity
E3U36_RS08345	COG0586	Pfam SNARE associated Golgi protein
E3U36_RS08350	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
E3U36_RS08355	COG0285	dihydrofolate synthase activity
E3U36_RS08360	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E3U36_RS08365	COG1286	toxin biosynthetic process
E3U36_RS08375	COG0163	prenyltransferase activity
E3U36_RS08390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E3U36_RS08395	COG1074	ATP-dependent DNA helicase activity
E3U36_RS08405	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E3U36_RS08440	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
E3U36_RS08445	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
E3U36_RS08450	COG0494	nUDIX hydrolase
E3U36_RS08455	COG4143	(ABC) transporter
E3U36_RS08460	COG1178	ABC-type Fe3 transport system permease component
E3U36_RS08465	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
E3U36_RS08480	COG0564	pseudouridine synthase activity
E3U36_RS08485	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
E3U36_RS08490	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E3U36_RS08495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E3U36_RS08500	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E3U36_RS08505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
E3U36_RS08510	COG2967	ApaG domain
E3U36_RS08515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E3U36_RS08530	COG0204	Acyl-transferase
E3U36_RS08535	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E3U36_RS08550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E3U36_RS08565	COG5463	Belongs to the UPF0441 family
E3U36_RS08570	COG0754	glutathionylspermidine amidase activity
E3U36_RS08580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E3U36_RS08605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
E3U36_RS08610	COG0227	Belongs to the bacterial ribosomal protein bL28 family
E3U36_RS08615	COG2003	Belongs to the UPF0758 family
E3U36_RS08620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E3U36_RS08625	COG0756	dUTP diphosphatase activity
E3U36_RS08630	COG1309	transcriptional regulator
E3U36_RS08635	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
E3U36_RS08640	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
E3U36_RS08645	COG1561	YicC-like family, N-terminal region
E3U36_RS08685	COG0205	6-phosphofructokinase activity
E3U36_RS08690	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E3U36_RS08695	COG1349	DNA-binding transcription factor activity
E3U36_RS08700	COG0705	Rhomboid family
E3U36_RS08705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E3U36_RS08715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E3U36_RS08715	COG0316	Belongs to the HesB IscA family
E3U36_RS08725	COG0596	Alpha beta hydrolase
E3U36_RS08740	COG1918	ferrous iron import across plasma membrane
E3U36_RS08755	COG2183	response to ionizing radiation
E3U36_RS08760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E3U36_RS08765	COG0745	RESPONSE REGULATOR receiver
E3U36_RS08780	COG0573	inorganic phosphate transmembrane transporter activity
E3U36_RS08800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E3U36_RS08805	COG0704	Plays a role in the regulation of phosphate uptake
E3U36_RS08825	COG0765	amino acid transport
E3U36_RS08830	COG2252	PERMEase
E3U36_RS08835	COG3078	GTPase activator activity
E3U36_RS08845	COG3078	GTPase activator activity
E3U36_RS08880	COG2860	membrane
E3U36_RS08885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E3U36_RS08890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E3U36_RS08905	COG0194	GDP metabolic process
E3U36_RS08910	COG1758	RNA polymerase activity
E3U36_RS08915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E3U36_RS08920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E3U36_RS08925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E3U36_RS08930	COG0786	glutamate:sodium symporter activity
E3U36_RS08960	COG2813	Specifically methylates the guanine in position
E3U36_RS08975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E3U36_RS09010	COG0189	ligase activity
E3U36_RS09015	COG1678	Uncharacterized ACR, COG1678
E3U36_RS09030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E3U36_RS09035	COG0762	integral membrane protein
E3U36_RS09040	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
E3U36_RS09045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E3U36_RS09075	COG0488	(ABC) transporter
E3U36_RS09100	COG0429	hydrolase of the alpha beta-hydrolase fold
E3U36_RS09110	COG3954	Phosphoribulokinase
E3U36_RS09125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3U36_RS09150	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
E3U36_RS09155	COG0538	isocitrate dehydrogenase activity
E3U36_RS09160	COG1187	pseudouridine synthase activity
E3U36_RS09170	COG0482	sulfurtransferase activity
E3U36_RS09175	COG2915	High frequency lysogenization protein hflD homolog
E3U36_RS09180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E3U36_RS09190	COG0745	RESPONSE REGULATOR receiver
E3U36_RS09215	COG4591	ABC-type transport system involved in lipoprotein release permease component
E3U36_RS09220	COG1136	(ABC) transporter
E3U36_RS09225	COG4591	ABC-type transport system involved in lipoprotein release permease component
E3U36_RS09235	COG1252	NADH dehydrogenase
E3U36_RS09245	COG0583	DNA-binding transcription factor activity
E3U36_RS09270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E3U36_RS09285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3U36_RS09285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
E3U36_RS09290	COG2204	response regulator
E3U36_RS09295	COG3170	Tfp pilus assembly protein FimV
E3U36_RS09300	COG2205	protein histidine kinase activity
E3U36_RS09310	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
E3U36_RS09325	COG2194	sulfuric ester hydrolase activity
E3U36_RS09335	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E3U36_RS09345	COG2969	positive regulation of protein catabolic process
E3U36_RS09350	COG0625	glutathione transferase activity
E3U36_RS09360	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
E3U36_RS09370	COG3105	Protein conserved in bacteria
E3U36_RS09375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3U36_RS09380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E3U36_RS09385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
E3U36_RS09390	COG5007	Belongs to the BolA IbaG family
E3U36_RS09400	COG2854	intermembrane phospholipid transfer
E3U36_RS09405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E3U36_RS09410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E3U36_RS09415	COG1127	ABC transporter
E3U36_RS09420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E3U36_RS09420	COG0517	IMP dehydrogenase activity
E3U36_RS09425	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E3U36_RS09430	COG3117	lipopolysaccharide transmembrane transporter activity
E3U36_RS09435	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E3U36_RS09440	COG1137	ATPase activity
E3U36_RS09445	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
E3U36_RS09450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E3U36_RS09460	COG1660	Displays ATPase and GTPase activities
E3U36_RS09465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E3U36_RS09475	COG3028	Belongs to the UPF0307 family
E3U36_RS09495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E3U36_RS09500	COG3164	Protein of unknown function
E3U36_RS09505	COG1530	ribonuclease E activity
E3U36_RS09510	COG0424	maF-like protein
E3U36_RS09515	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E3U36_RS09520	COG1792	Involved in formation and maintenance of cell shape
E3U36_RS09525	COG1077	Cell shape determining protein MreB Mrl
E3U36_RS09540	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
E3U36_RS09545	COG0511	ligase activity, forming carbon-carbon bonds
E3U36_RS09550	COG0439	Biotin carboxylase
E3U36_RS09555	COG3924	membrane
E3U36_RS09560	COG4145	pantothenate transmembrane transporter activity
E3U36_RS09565	COG2264	protein methyltransferase activity
E3U36_RS09570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3U36_RS09575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E3U36_RS09590	COG2177	Part of the ABC transporter FtsEX involved in
E3U36_RS09595	COG2884	Cell division ATP-binding protein ftsE
E3U36_RS09600	COG0552	protein localization to endoplasmic reticulum
E3U36_RS09605	COG0742	ribosomal rna small subunit methyltransferase
E3U36_RS09610	COG3776	membrane
E3U36_RS09620	COG3714	YhhN family
E3U36_RS09630	COG0425	Belongs to the sulfur carrier protein TusA family
E3U36_RS09635	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E3U36_RS09700	COG0583	DNA-binding transcription factor activity
E3U36_RS09715	COG0628	permease
E3U36_RS09730	COG0316	Belongs to the HesB IscA family
E3U36_RS09735	COG0719	Fe-S assembly protein
E3U36_RS09740	COG0396	ATPase activity
E3U36_RS09745	COG0719	Fe-S assembly protein
E3U36_RS09750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E3U36_RS09755	COG2166	iron-sulfur cluster assembly
E3U36_RS09760	COG1376	ErfK ybiS ycfS ynhG family protein
E3U36_RS09760	COG1388	LysM domain
E3U36_RS09765	COG4238	major outer membrane lipoprotein
E3U36_RS09770	COG0469	pyruvate kinase activity
E3U36_RS09790	COG1560	Kdo2-lipid A biosynthetic process
E3U36_RS09800	COG0739	heme binding
E3U36_RS09805	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E3U36_RS09810	COG1121	(ABC) transporter
E3U36_RS09815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3U36_RS09820	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E3U36_RS09830	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
E3U36_RS09835	COG2894	cell division
E3U36_RS09840	COG0850	regulation of cytokinetic process
E3U36_RS09845	COG3100	YcgL domain-containing protein
E3U36_RS09860	COG0179	Fumarylacetoacetate (FAA) hydrolase
E3U36_RS09865	COG2983	Belongs to the UPF0260 family
E3U36_RS09885	COG2911	Protein conserved in bacteria
E3U36_RS09895	COG2911	Protein conserved in bacteria
E3U36_RS09905	COG3784	Protein of unknown function (DUF1318)
E3U36_RS09925	COG3188	usher protein
E3U36_RS09955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E3U36_RS09980	COG0604	alcohol dehydrogenase
E3U36_RS09980	COG1028	Short-chain dehydrogenase reductase Sdr
E3U36_RS09980	COG3321	synthase
E3U36_RS09995	COG0450	alkyl hydroperoxide reductase
E3U36_RS10035	COG1760	l-serine dehydratase
E3U36_RS10040	COG0814	amino acid
E3U36_RS10050	COG3264	Mechanosensitive ion channel
E3U36_RS10050	COG1196	nuclear chromosome segregation
E3U36_RS10055	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E3U36_RS10060	COG1309	transcriptional regulator
E3U36_RS10065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E3U36_RS10070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E3U36_RS10110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E3U36_RS10120	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E3U36_RS10125	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
E3U36_RS10130	COG0740	serine-type endopeptidase activity
E3U36_RS10140	COG0271	Belongs to the BolA IbaG family
E3U36_RS10165	COG0519	Catalyzes the synthesis of GMP from XMP
E3U36_RS10165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
E3U36_RS10170	COG0517	IMP dehydrogenase activity
E3U36_RS10170	COG0516	GMP reductase activity
E3U36_RS10190	COG0281	malic enzyme
E3U36_RS10190	COG0280	phosphate acetyltransferase
E3U36_RS10205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E3U36_RS10315	COG0418	dihydroorotase activity
E3U36_RS10345	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E3U36_RS10350	COG1959	2 iron, 2 sulfur cluster binding
E3U36_RS10360	COG0822	iron-sulfur transferase activity
E3U36_RS10365	COG0316	Belongs to the HesB IscA family
E3U36_RS10390	COG2771	luxR family
E3U36_RS10400	COG5464	transposase or invertase
E3U36_RS10450	COG0471	metal ion transport
E3U36_RS10460	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
E3U36_RS10470	COG2982	Protein involved in outer membrane biogenesis
E3U36_RS10475	COG0717	Belongs to the dCTP deaminase family
E3U36_RS10485	COG0489	protein tyrosine kinase activity
E3U36_RS10490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3U36_RS10490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3U36_RS10495	COG1380	Effector of murein hydrolase LrgA
E3U36_RS10500	COG1346	cytolysis
E3U36_RS10505	COG2949	membrane
E3U36_RS10510	COG2311	Membrane
E3U36_RS10515	COG2311	Membrane
E3U36_RS10530	COG0302	gtp cyclohydrolase
E3U36_RS10545	COG0303	'Molybdopterin
E3U36_RS10550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E3U36_RS10575	COG0783	Belongs to the Dps family
E3U36_RS10580	COG2824	Alkylphosphonate utilization operon protein PhnA
E3U36_RS10590	COG2897	thiosulfate sulfurtransferase activity
E3U36_RS10595	COG2261	transglycosylase associated protein
E3U36_RS10630	COG0670	Belongs to the BI1 family
E3U36_RS10645	COG0315	cyclic pyranopterin monophosphate synthase activity
E3U36_RS10655	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E3U36_RS10660	COG0556	nucleotide-excision repair
E3U36_RS10690	COG2706	6-phosphogluconolactonase activity
E3U36_RS10710	COG3104	oligopeptide transport
E3U36_RS10740	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E3U36_RS10745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E3U36_RS10750	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
E3U36_RS10760	COG2239	Acts as a magnesium transporter
E3U36_RS10775	COG0159	tryptophan synthase activity
E3U36_RS10795	COG2917	probably involved in intracellular septation
E3U36_RS10805	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
E3U36_RS10820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E3U36_RS10830	COG2095	MarC family integral membrane protein
E3U36_RS10865	COG0745	RESPONSE REGULATOR receiver
E3U36_RS10870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E3U36_RS10900	COG1435	thymidine kinase activity
E3U36_RS10915	COG0788	formyltetrahydrofolate deformylase activity
E3U36_RS10935	COG0708	Exodeoxyribonuclease III
E3U36_RS10940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E3U36_RS10950	COG0778	Nitroreductase
E3U36_RS10955	COG0616	signal peptide processing
E3U36_RS10965	COG3139	Protein of unknown function (DUF1315)
E3U36_RS10970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E3U36_RS11025	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E3U36_RS11035	COG3768	UPF0283 membrane protein
E3U36_RS11045	COG1983	PspC domain protein
E3U36_RS11065	COG1842	Phage shock protein A
E3U36_RS11075	COG4166	transmembrane transport
E3U36_RS11080	COG4168	peptide transport system, permease
E3U36_RS11085	COG4171	peptide transport system, permease
E3U36_RS11090	COG4172	Belongs to the ABC transporter superfamily
E3U36_RS11095	COG4172	Belongs to the ABC transporter superfamily
E3U36_RS11100	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E3U36_RS11165	COG1560	Kdo2-lipid A biosynthetic process
E3U36_RS11185	COG0563	adenylate kinase activity
E3U36_RS11190	COG0326	Molecular chaperone. Has ATPase activity
E3U36_RS11200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E3U36_RS11205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E3U36_RS11210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E3U36_RS11235	COG0848	biopolymer transport protein
E3U36_RS11255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E3U36_RS11260	COG0505	Belongs to the CarA family
E3U36_RS11265	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
E3U36_RS11275	COG1047	Peptidyl-prolyl cis-trans
E3U36_RS11280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
E3U36_RS11285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
E3U36_RS11290	COG0196	riboflavin kinase activity
E3U36_RS11295	COG0268	Binds directly to 16S ribosomal RNA
E3U36_RS11310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E3U36_RS11345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E3U36_RS11355	COG1803	Methylglyoxal synthase
E3U36_RS11365	COG3785	DNA binding
E3U36_RS11370	COG1254	Belongs to the acylphosphatase family
E3U36_RS11375	COG2920	part of a sulfur-relay system
E3U36_RS11410	COG0716	FMN binding
E3U36_RS11415	COG0735	belongs to the Fur family
E3U36_RS11440	COG0612	Peptidase, M16
E3U36_RS11445	COG1295	ribonuclease BN
E3U36_RS11475	COG1317	bacterial-type flagellum organization
E3U36_RS11480	COG3137	Salt-induced outer membrane protein
E3U36_RS11515	COG0589	response to stress
E3U36_RS11545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3U36_RS11550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E3U36_RS11555	COG0006	proline dipeptidase activity
E3U36_RS11560	COG3079	Belongs to the UPF0149 family
E3U36_RS11565	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
E3U36_RS11590	COG0148	phosphopyruvate hydratase activity
E3U36_RS11595	COG0504	CTP synthase activity
E3U36_RS11600	COG3956	TIGRFAM MazG family protein
E3U36_RS11610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E3U36_RS11625	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E3U36_RS11630	COG0316	Belongs to the HesB IscA family
E3U36_RS11635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
E3U36_RS11640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E3U36_RS11645	COG1489	DNA binding
E3U36_RS11665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3U36_RS11685	COG2333	competence protein COMEC
E3U36_RS11685	COG0658	competence protein
E3U36_RS11690	COG0658	competence protein
E3U36_RS11690	COG2333	competence protein COMEC
E3U36_RS11695	COG1132	(ABC) transporter
E3U36_RS11700	COG1663	tetraacyldisaccharide 4'-kinase activity
E3U36_RS11705	COG1278	Cold shock
E3U36_RS11710	COG2835	tetraacyldisaccharide 4'-kinase activity
E3U36_RS11715	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
E3U36_RS11730	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
E3U36_RS11735	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E3U36_RS11740	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
E3U36_RS11795	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
E3U36_RS11795	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
E3U36_RS11810	COG0564	pseudouridine synthase activity
E3U36_RS11825	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
E3U36_RS11840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
E3U36_RS11845	COG0528	UMP kinase activity
E3U36_RS11850	COG0233	cytoplasmic translational termination
E3U36_RS11855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
E3U36_RS11860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E3U36_RS11865	COG0575	Belongs to the CDS family
E3U36_RS11870	COG0750	zinc metalloprotease
E3U36_RS11875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3U36_RS11880	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
E3U36_RS11885	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E3U36_RS11890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E3U36_RS11895	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E3U36_RS11900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
E3U36_RS11910	COG0825	malonyl-CoA metabolic process
E3U36_RS11915	COG0037	tRNA processing
E3U36_RS11920	COG4568	rho-dependent transcription termination
E3U36_RS11925	COG3015	lipoprotein NlpE involved in copper resistance
E3U36_RS11930	COG0442	prolyl-tRNA aminoacylation
E3U36_RS11935	COG1720	tRNA m6t6A37 methyltransferase activity
E3U36_RS11955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E3U36_RS11960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E3U36_RS12000	COG1988	membrane-bound metal-dependent
E3U36_RS12005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E3U36_RS12025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E3U36_RS12040	COG0803	Belongs to the bacterial solute-binding protein 9 family
E3U36_RS12050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E3U36_RS12055	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
E3U36_RS12060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
E3U36_RS12065	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
E3U36_RS12075	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
E3U36_RS12080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E3U36_RS12080	COG0072	phenylalanine-tRNA ligase activity
E3U36_RS12085	COG0776	regulation of translation
E3U36_RS12090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E3U36_RS12095	COG0463	Glycosyl transferase, family 2
E3U36_RS12100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E3U36_RS12100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E3U36_RS12105	COG0726	polysaccharide deacetylase
E3U36_RS12110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
E3U36_RS12115	COG2076	Multidrug Resistance protein
E3U36_RS12120	COG2076	Multidrug Resistance protein
E3U36_RS12125	COG0791	NLP P60 protein
E3U36_RS12280	COG0071	Belongs to the small heat shock protein (HSP20) family
E3U36_RS12300	COG1278	Cold shock