locus-tag	class	description
AOC05_RS00010	COG0588	phosphoglycerate mutase activity
AOC05_RS00015	COG0704	Plays a role in the regulation of phosphate uptake
AOC05_RS00020	COG5002	protein histidine kinase activity
AOC05_RS00040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AOC05_RS00045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AOC05_RS00050	COG0215	cysteine-tRNA ligase activity
AOC05_RS00055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOC05_RS00070	COG0366	Alpha amylase catalytic
AOC05_RS00075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AOC05_RS00120	COG0277	FAD linked oxidase domain protein
AOC05_RS00135	COG3842	ATPase activity
AOC05_RS00250	COG0629	single-stranded DNA binding
AOC05_RS00255	COG1192	Involved in chromosome partitioning
AOC05_RS00285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOC05_RS00360	COG0277	FAD linked oxidase domain protein
AOC05_RS00365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOC05_RS00370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOC05_RS00375	COG2814	Major facilitator Superfamily
AOC05_RS00390	COG1024	Enoyl-CoA hydratase
AOC05_RS00395	COG1024	Enoyl-CoA hydratase
AOC05_RS00410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOC05_RS00415	COG0477	Major facilitator Superfamily
AOC05_RS00430	COG1024	Enoyl-CoA hydratase
AOC05_RS00445	COG1940	carbohydrate kinase activity
AOC05_RS00450	COG0366	Alpha amylase catalytic
AOC05_RS00455	COG0395	ABC-type sugar transport system, permease component
AOC05_RS00460	COG1175	transmembrane transport
AOC05_RS00470	COG1940	carbohydrate kinase activity
AOC05_RS00525	COG0747	negative chemotaxis
AOC05_RS00540	COG4608	Belongs to the ABC transporter superfamily
AOC05_RS00545	COG0673	inositol 2-dehydrogenase activity
AOC05_RS00550	COG0673	inositol 2-dehydrogenase activity
AOC05_RS00570	COG0395	ABC-type sugar transport system, permease component
AOC05_RS00575	COG1175	transmembrane transport
AOC05_RS00600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOC05_RS00610	COG0730	response to heat
AOC05_RS00615	COG0477	Major facilitator Superfamily
AOC05_RS00625	COG1937	Protein conserved in bacteria
AOC05_RS00640	COG1846	Transcriptional regulator
AOC05_RS00640	COG1940	carbohydrate kinase activity
AOC05_RS00645	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AOC05_RS00650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AOC05_RS00655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOC05_RS00660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOC05_RS00680	COG1940	carbohydrate kinase activity
AOC05_RS00685	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS00690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOC05_RS00695	COG0251	oxidation-reduction process
AOC05_RS00700	COG0477	Major facilitator Superfamily
AOC05_RS00710	COG0028	Belongs to the TPP enzyme family
AOC05_RS00715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOC05_RS00720	COG2826	transposase and inactivated derivatives, IS30 family
AOC05_RS00765	COG3142	Participates in the control of copper homeostasis
AOC05_RS00810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOC05_RS00815	COG4133	protoheme IX ABC transporter activity
AOC05_RS00820	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AOC05_RS00825	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOC05_RS00830	COG1129	ABC transporter
AOC05_RS00835	COG1869	D-ribose catabolic process
AOC05_RS00840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOC05_RS00845	COG1609	Transcriptional regulator
AOC05_RS00855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AOC05_RS00875	COG1960	acyl-CoA dehydrogenase activity
AOC05_RS00885	COG1309	transcriptional regulator
AOC05_RS00905	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS00910	COG0477	Major facilitator Superfamily
AOC05_RS00915	COG2030	dehydratase
AOC05_RS00925	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOC05_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS00980	COG1024	Enoyl-CoA hydratase
AOC05_RS00995	COG2080	2 iron, 2 sulfur cluster binding
AOC05_RS01010	COG3608	succinylglutamate desuccinylase aspartoacylase
AOC05_RS01010	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AOC05_RS01015	COG1802	Transcriptional regulator
AOC05_RS01020	COG1335	isochorismatase
AOC05_RS01035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOC05_RS01040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOC05_RS01045	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AOC05_RS01050	COG0066	3-isopropylmalate dehydratase activity
AOC05_RS01080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOC05_RS01085	COG0165	Argininosuccinate lyase
AOC05_RS01090	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AOC05_RS01095	COG3842	ATPase activity
AOC05_RS01105	COG1940	carbohydrate kinase activity
AOC05_RS01110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOC05_RS01125	COG1960	acyl-CoA dehydrogenase activity
AOC05_RS01135	COG0183	Belongs to the thiolase family
AOC05_RS01140	COG0183	Belongs to the thiolase family
AOC05_RS01145	COG0318	PFAM AMP-dependent synthetase and ligase
AOC05_RS01165	COG0183	Belongs to the thiolase family
AOC05_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
AOC05_RS01175	COG2070	2-Nitropropane dioxygenase
AOC05_RS01250	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOC05_RS01270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOC05_RS01275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOC05_RS01280	COG0277	FAD linked oxidase domain protein
AOC05_RS01330	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS01345	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS01355	COG1024	Enoyl-CoA hydratase
AOC05_RS01380	COG1136	(ABC) transporter
AOC05_RS01415	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AOC05_RS01430	COG0459	protein refolding
AOC05_RS01435	COG0328	RNA-DNA hybrid ribonuclease activity
AOC05_RS01445	COG2205	protein histidine kinase activity
AOC05_RS01450	COG0745	RESPONSE REGULATOR receiver
AOC05_RS01455	COG3119	arylsulfatase activity
AOC05_RS01465	COG3119	arylsulfatase activity
AOC05_RS01470	COG0395	ABC-type sugar transport system, permease component
AOC05_RS01490	COG0673	inositol 2-dehydrogenase activity
AOC05_RS01505	COG3119	arylsulfatase activity
AOC05_RS01525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOC05_RS01570	COG1278	Cold shock
AOC05_RS01585	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AOC05_RS01595	COG0739	heme binding
AOC05_RS01600	COG0791	NLP P60 protein
AOC05_RS01600	COG3103	Sh3 type 3 domain protein
AOC05_RS01600	COG1388	LysM domain
AOC05_RS01615	COG0746	molybdenum cofactor guanylyltransferase activity
AOC05_RS01650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOC05_RS01675	COG1126	abc transporter atp-binding protein
AOC05_RS01680	COG0765	amino acid transport
AOC05_RS01685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOC05_RS01690	COG1132	(ABC) transporter
AOC05_RS01695	COG1742	UPF0060 membrane protein
AOC05_RS01700	COG2962	Rard protein
AOC05_RS01715	COG0483	inositol monophosphate 1-phosphatase activity
AOC05_RS01730	COG0045	succinate-CoA ligase (ADP-forming) activity
AOC05_RS01755	COG1414	Transcriptional regulator
AOC05_RS01765	COG0477	Major facilitator Superfamily
AOC05_RS01795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOC05_RS01820	COG1760	l-serine dehydratase
AOC05_RS01850	COG1396	sequence-specific DNA binding
AOC05_RS01865	COG0028	Belongs to the TPP enzyme family
AOC05_RS01885	COG1309	transcriptional regulator
AOC05_RS01890	COG1090	epimerase
AOC05_RS01910	COG2186	Transcriptional regulator
AOC05_RS01920	COG1027	Aspartate ammonia-lyase
AOC05_RS01980	COG1185	polyribonucleotide nucleotidyltransferase activity
AOC05_RS02015	COG2801	Transposase and inactivated derivatives
AOC05_RS02065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOC05_RS02085	COG3634	alkyl hydroperoxide reductase activity
AOC05_RS02100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOC05_RS02120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOC05_RS02120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOC05_RS02130	COG1278	Cold shock
AOC05_RS02155	COG0477	Major facilitator Superfamily
AOC05_RS02160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOC05_RS02165	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AOC05_RS02170	COG1472	Belongs to the glycosyl hydrolase 3 family
AOC05_RS02175	COG0138	bifunctional purine biosynthesis protein purh
AOC05_RS02185	COG2838	Isocitrate dehydrogenase
AOC05_RS02215	COG0673	inositol 2-dehydrogenase activity
AOC05_RS02220	COG4213	ABC transporter substrate-binding protein
AOC05_RS02225	COG4214	carbohydrate transport
AOC05_RS02250	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOC05_RS02255	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AOC05_RS02270	COG2197	response regulator
AOC05_RS02295	COG0180	Tryptophanyl-tRNA synthetase
AOC05_RS02315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOC05_RS02330	COG2009	succinate dehydrogenase
AOC05_RS02340	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOC05_RS02340	COG1473	amidohydrolase
AOC05_RS02350	COG3845	ABC transporter
AOC05_RS02355	COG4603	Belongs to the binding-protein-dependent transport system permease family
AOC05_RS02360	COG1079	Belongs to the binding-protein-dependent transport system permease family
AOC05_RS02375	COG0586	Pfam SNARE associated Golgi protein
AOC05_RS02380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOC05_RS02385	COG3956	TIGRFAM MazG family protein
AOC05_RS02395	COG0148	phosphopyruvate hydratase activity
AOC05_RS02415	COG1404	Belongs to the peptidase S8 family
AOC05_RS02445	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AOC05_RS02455	COG1349	DNA-binding transcription factor activity
AOC05_RS02460	COG2017	converts alpha-aldose to the beta-anomer
AOC05_RS02470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOC05_RS02475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOC05_RS02485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOC05_RS02495	COG1331	Highly conserved protein containing a thioredoxin domain
AOC05_RS02500	COG1136	(ABC) transporter
AOC05_RS02515	COG0577	efflux transmembrane transporter activity
AOC05_RS02530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOC05_RS02535	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AOC05_RS02570	COG0114	fumarate hydratase activity
AOC05_RS02575	COG0288	reversible hydration of carbon dioxide
AOC05_RS02585	COG1494	fructose-1,6-bisphosphatase
AOC05_RS02595	COG1482	cell wall glycoprotein biosynthetic process
AOC05_RS02600	COG1316	TRANSCRIPTIONal
AOC05_RS02655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOC05_RS02660	COG1376	ErfK ybiS ycfS ynhG family protein
AOC05_RS02705	COG0714	Associated with various cellular activities
AOC05_RS02710	COG0084	hydrolase, TatD family'
AOC05_RS02715	COG3583	domain protein
AOC05_RS02720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOC05_RS02725	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AOC05_RS02730	COG0488	(ABC) transporter
AOC05_RS02745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AOC05_RS02760	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AOC05_RS02765	COG0193	aminoacyl-tRNA hydrolase activity
AOC05_RS02775	COG2197	response regulator
AOC05_RS02780	COG2197	response regulator
AOC05_RS02785	COG0529	Catalyzes the synthesis of activated sulfate
AOC05_RS02790	COG0730	response to heat
AOC05_RS02825	COG1218	3'(2'),5'-bisphosphate nucleotidase
AOC05_RS02845	COG1215	transferase activity, transferring glycosyl groups
AOC05_RS02910	COG0822	iron-sulfur transferase activity
AOC05_RS02920	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOC05_RS02930	COG5002	protein histidine kinase activity
AOC05_RS02960	COG5002	protein histidine kinase activity
AOC05_RS02965	COG0745	RESPONSE REGULATOR receiver
AOC05_RS02985	COG3979	chitinase
AOC05_RS03010	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AOC05_RS03020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOC05_RS03040	COG0477	Major facilitator Superfamily
AOC05_RS03050	COG2801	Transposase and inactivated derivatives
AOC05_RS03055	COG4770	biotin carboxylase activity
AOC05_RS03070	COG0424	maF-like protein
AOC05_RS03095	COG2409	Drug exporters of the RND superfamily
AOC05_RS03110	COG1823	symporter activity
AOC05_RS03130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOC05_RS03180	COG0714	Associated with various cellular activities
AOC05_RS03190	COG1305	Transglutaminase-like
AOC05_RS03230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOC05_RS03240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOC05_RS03260	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOC05_RS03265	COG0154	amidase activity
AOC05_RS03270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOC05_RS03295	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOC05_RS03300	COG0583	DNA-binding transcription factor activity
AOC05_RS03305	COG1063	alcohol dehydrogenase
AOC05_RS03310	COG0156	8-amino-7-oxononanoate synthase activity
AOC05_RS03315	COG1228	amidohydrolase
AOC05_RS03330	COG1940	carbohydrate kinase activity
AOC05_RS03345	COG1349	DNA-binding transcription factor activity
AOC05_RS03350	COG2837	iron assimilation
AOC05_RS03355	COG2822	iron ion transport
AOC05_RS03365	COG0588	phosphoglycerate mutase activity
AOC05_RS03390	COG2183	response to ionizing radiation
AOC05_RS03395	COG2873	o-acetylhomoserine
AOC05_RS03400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOC05_RS03435	COG0423	glycine-tRNA ligase activity
AOC05_RS03455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOC05_RS03460	COG3424	synthase
AOC05_RS03465	COG2239	Acts as a magnesium transporter
AOC05_RS03470	COG1309	transcriptional regulator
AOC05_RS03475	COG1511	domain protein
AOC05_RS03480	COG4133	protoheme IX ABC transporter activity
AOC05_RS03495	COG0358	DNA primase activity
AOC05_RS03510	COG2814	Major facilitator Superfamily
AOC05_RS03530	COG0297	glycogen (starch) synthase activity
AOC05_RS03540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOC05_RS03555	COG0052	Belongs to the universal ribosomal protein uS2 family
AOC05_RS03560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AOC05_RS03565	COG0528	UMP kinase activity
AOC05_RS03570	COG0233	cytoplasmic translational termination
AOC05_RS03575	COG0575	Belongs to the CDS family
AOC05_RS03585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOC05_RS03600	COG3275	phosphorelay sensor kinase activity
AOC05_RS03630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOC05_RS03635	COG1522	sequence-specific DNA binding
AOC05_RS03645	COG0022	dehydrogenase e1 component
AOC05_RS03650	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOC05_RS03665	COG1309	transcriptional regulator
AOC05_RS03670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOC05_RS03680	COG1960	acyl-CoA dehydrogenase activity
AOC05_RS03705	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AOC05_RS03710	COG0750	zinc metalloprotease
AOC05_RS03730	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AOC05_RS03740	COG1902	pentaerythritol trinitrate reductase activity
AOC05_RS03740	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOC05_RS03755	COG1309	transcriptional regulator
AOC05_RS03775	COG0442	prolyl-tRNA aminoacylation
AOC05_RS03785	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
AOC05_RS03800	COG0779	Required for maturation of 30S ribosomal subunits
AOC05_RS03805	COG0195	Participates in both transcription termination and antitermination
AOC05_RS03810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AOC05_RS03815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AOC05_RS03850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOC05_RS03875	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AOC05_RS03880	COG1185	polyribonucleotide nucleotidyltransferase activity
AOC05_RS03885	COG0612	Peptidase, M16
AOC05_RS03930	COG0315	cyclic pyranopterin monophosphate synthase activity
AOC05_RS03935	COG0315	cyclic pyranopterin monophosphate synthase activity
AOC05_RS03935	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOC05_RS03945	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AOC05_RS03955	COG0596	Alpha beta hydrolase
AOC05_RS03960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOC05_RS03965	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOC05_RS03970	COG1674	ftsk spoiiie
AOC05_RS03980	COG1546	Belongs to the CinA family
AOC05_RS03980	COG1058	Belongs to the CinA family
AOC05_RS04000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AOC05_RS04005	COG2137	regulation of response to DNA damage stimulus
AOC05_RS04015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOC05_RS04020	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AOC05_RS04025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AOC05_RS04030	COG2813	Specifically methylates the guanine in position
AOC05_RS04035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOC05_RS04045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AOC05_RS04055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOC05_RS04060	COG0131	Imidazoleglycerol-phosphate dehydratase
AOC05_RS04065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOC05_RS04070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AOC05_RS04090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AOC05_RS04095	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AOC05_RS04100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AOC05_RS04105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOC05_RS04115	COG2814	Major facilitator Superfamily
AOC05_RS04140	COG0318	PFAM AMP-dependent synthetase and ligase
AOC05_RS04160	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AOC05_RS04165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOC05_RS04165	COG0072	phenylalanine-tRNA ligase activity
AOC05_RS04225	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AOC05_RS04230	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOC05_RS04235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AOC05_RS04240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOC05_RS04245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AOC05_RS04250	COG1438	arginine binding
AOC05_RS04255	COG0137	argininosuccinate synthase activity
AOC05_RS04260	COG0165	Argininosuccinate lyase
AOC05_RS04280	COG2094	Belongs to the DNA glycosylase MPG family
AOC05_RS04285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOC05_RS04295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOC05_RS04340	COG0647	UMP catabolic process
AOC05_RS04350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOC05_RS04355	COG0497	DNA recombination
AOC05_RS04360	COG0504	CTP synthase activity
AOC05_RS04365	COG0494	nUDIX hydrolase
AOC05_RS04400	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS04405	COG3387	PFAM Glycoside hydrolase 15-related
AOC05_RS04410	COG2816	NAD+ diphosphatase activity
AOC05_RS04425	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOC05_RS04430	COG2079	MmgE PrpD family protein
AOC05_RS04450	COG3290	protein histidine kinase activity
AOC05_RS04455	COG1301	dicarboxylic acid transport
AOC05_RS04480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AOC05_RS04485	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOC05_RS04500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AOC05_RS04510	COG1160	GTP binding
AOC05_RS04535	COG1960	acyl-CoA dehydrogenase activity
AOC05_RS04555	COG0509	glycine decarboxylation via glycine cleavage system
AOC05_RS04560	COG1716	ATPase activity
AOC05_RS04585	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOC05_RS04585	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOC05_RS04590	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AOC05_RS04605	COG1940	carbohydrate kinase activity
AOC05_RS04625	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AOC05_RS04630	COG1403	HNH endonuclease
AOC05_RS04635	COG2815	serine threonine protein kinase
AOC05_RS04635	COG0515	serine threonine protein kinase
AOC05_RS04650	COG0142	geranyltranstransferase activity
AOC05_RS04665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOC05_RS04675	COG2001	Belongs to the MraZ family
AOC05_RS04680	COG0275	rRNA processing
AOC05_RS04690	COG0768	penicillin binding
AOC05_RS04705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOC05_RS04710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AOC05_RS04720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AOC05_RS04725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOC05_RS04730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOC05_RS04735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOC05_RS04740	COG1496	oxidoreductase activity
AOC05_RS04750	COG1799	cell septum assembly
AOC05_RS04765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AOC05_RS04775	COG0587	DNA-directed DNA polymerase activity
AOC05_RS04785	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOC05_RS04790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AOC05_RS04805	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AOC05_RS04810	COG0174	glutamine synthetase
AOC05_RS04815	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AOC05_RS04825	COG2066	Belongs to the glutaminase family
AOC05_RS04865	COG4974	Belongs to the 'phage' integrase family
AOC05_RS05050	COG2801	Transposase and inactivated derivatives
AOC05_RS05075	COG0305	Participates in initiation and elongation during chromosome replication
AOC05_RS05115	COG4974	Belongs to the 'phage' integrase family
AOC05_RS05145	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOC05_RS05150	COG0321	lipoyl(octanoyl) transferase activity
AOC05_RS05160	COG0793	Belongs to the peptidase S41A family
AOC05_RS05160	COG4946	Tricorn protease homolog
AOC05_RS05175	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOC05_RS05180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOC05_RS05185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOC05_RS05205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOC05_RS05230	COG1271	oxidase subunit
AOC05_RS05235	COG1294	oxidase, subunit
AOC05_RS05240	COG4988	ABC transporter
AOC05_RS05255	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOC05_RS05285	COG0756	dUTP diphosphatase activity
AOC05_RS05310	COG0569	domain protein
AOC05_RS05315	COG0531	amino acid
AOC05_RS05320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOC05_RS05325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOC05_RS05330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOC05_RS05335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AOC05_RS05355	COG0667	Aldo Keto reductase
AOC05_RS05365	COG1024	Enoyl-CoA hydratase
AOC05_RS05365	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOC05_RS05370	COG0183	Belongs to the thiolase family
AOC05_RS05375	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AOC05_RS05400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOC05_RS05415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOC05_RS05440	COG2072	flavoprotein involved in K transport
AOC05_RS05490	COG0242	peptide deformylase activity
AOC05_RS05495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AOC05_RS05505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOC05_RS05510	COG3201	nicotinamide mononucleotide transporter
AOC05_RS05525	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOC05_RS05525	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOC05_RS05530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOC05_RS05530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOC05_RS05535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AOC05_RS05540	COG0140	phosphoribosyl-ATP diphosphatase activity
AOC05_RS05545	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOC05_RS05550	COG0107	imidazoleglycerol-phosphate synthase activity
AOC05_RS05560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AOC05_RS05580	COG0134	indole-3-glycerol-phosphate synthase activity
AOC05_RS05585	COG0133	tryptophan synthase activity
AOC05_RS05590	COG0159	tryptophan synthase activity
AOC05_RS05595	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AOC05_RS05600	COG0069	glutamate synthase activity
AOC05_RS05600	COG0070	glutamate synthase
AOC05_RS05600	COG0067	glutamate synthase
AOC05_RS05640	COG3654	unkown
AOC05_RS05650	COG0019	diaminopimelate decarboxylase activity
AOC05_RS05660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOC05_RS05665	COG2261	transglycosylase associated protein
AOC05_RS05685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOC05_RS05705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOC05_RS05710	COG0667	Aldo Keto reductase
AOC05_RS05715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOC05_RS05720	COG1121	(ABC) transporter
AOC05_RS05760	COG0542	response to heat
AOC05_RS05775	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOC05_RS05780	COG0022	dehydrogenase e1 component
AOC05_RS05785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOC05_RS05795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AOC05_RS05800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOC05_RS05805	COG1053	succinate dehydrogenase
AOC05_RS05870	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AOC05_RS05890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOC05_RS05905	COG3285	dna ligase
AOC05_RS05905	COG1793	dna ligase
AOC05_RS05915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOC05_RS05915	COG0574	Belongs to the PEP-utilizing enzyme family
AOC05_RS05925	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AOC05_RS05955	COG1063	alcohol dehydrogenase
AOC05_RS05970	COG2205	protein histidine kinase activity
AOC05_RS05990	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AOC05_RS06010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOC05_RS06015	COG0589	response to stress
AOC05_RS06020	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AOC05_RS06030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOC05_RS06050	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOC05_RS06060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOC05_RS06095	COG0804	urea catabolic process
AOC05_RS06100	COG1902	pentaerythritol trinitrate reductase activity
AOC05_RS06115	COG2130	NADP-dependent
AOC05_RS06135	COG2226	methyltransferase
AOC05_RS06155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOC05_RS06160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOC05_RS06170	COG2814	Major facilitator Superfamily
AOC05_RS06175	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS06180	COG3119	arylsulfatase activity
AOC05_RS06200	COG1940	carbohydrate kinase activity
AOC05_RS06200	COG1846	Transcriptional regulator
AOC05_RS06215	COG2268	Band 7 protein
AOC05_RS06250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AOC05_RS06265	COG1902	pentaerythritol trinitrate reductase activity
AOC05_RS06315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOC05_RS06320	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AOC05_RS06325	COG1643	Atp-dependent helicase
AOC05_RS06330	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS06335	COG0783	Belongs to the Dps family
AOC05_RS06340	COG0009	L-threonylcarbamoyladenylate synthase
AOC05_RS06345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOC05_RS06370	COG0477	Major facilitator Superfamily
AOC05_RS06395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOC05_RS06410	COG0673	inositol 2-dehydrogenase activity
AOC05_RS06430	COG0436	Aminotransferase
AOC05_RS06435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOC05_RS06455	COG2050	protein possibly involved in aromatic compounds catabolism
AOC05_RS06480	COG0539	negative regulation of cytoplasmic translation
AOC05_RS06485	COG3152	Membrane
AOC05_RS06490	COG1739	Uncharacterized protein family UPF0029
AOC05_RS06495	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOC05_RS06495	COG0237	dephospho-CoA kinase activity
AOC05_RS06505	COG0556	nucleotide-excision repair
AOC05_RS06525	COG4106	trans-aconitate 2-methyltransferase activity
AOC05_RS06535	COG3550	peptidyl-serine autophosphorylation
AOC05_RS06555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOC05_RS06565	COG0546	phosphoglycolate phosphatase activity
AOC05_RS06575	COG0322	excinuclease ABC activity
AOC05_RS06580	COG1660	Displays ATPase and GTPase activities
AOC05_RS06590	COG1481	regulation of sporulation
AOC05_RS06600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOC05_RS06605	COG0126	phosphoglycerate kinase activity
AOC05_RS06610	COG0149	triose-phosphate isomerase activity
AOC05_RS06615	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOC05_RS06620	COG0363	glucosamine-6-phosphate deaminase activity
AOC05_RS06635	COG0166	Belongs to the GPI family
AOC05_RS06640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOC05_RS06650	COG0109	protoheme IX farnesyltransferase activity
AOC05_RS06665	COG1131	(ABC) transporter
AOC05_RS06690	COG0396	ATPase activity
AOC05_RS06695	COG2151	metal-sulfur cluster biosynthetic enzyme
AOC05_RS06700	COG0318	PFAM AMP-dependent synthetase and ligase
AOC05_RS06705	COG0183	Belongs to the thiolase family
AOC05_RS06715	COG1122	ATPase activity
AOC05_RS06720	COG1268	BioY protein
AOC05_RS06725	COG0488	(ABC) transporter
AOC05_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS06755	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS06760	COG3830	Belongs to the UPF0237 family
AOC05_RS06760	COG0560	Phosphoserine phosphatase
AOC05_RS06765	COG1119	ATPase activity
AOC05_RS06770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOC05_RS06780	COG0254	rRNA binding
AOC05_RS06800	COG2855	membrane
AOC05_RS06810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOC05_RS06815	COG0297	glycogen (starch) synthase activity
AOC05_RS06820	COG1403	HNH endonuclease
AOC05_RS06850	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS06860	COG0477	Major facilitator Superfamily
AOC05_RS06870	COG0577	efflux transmembrane transporter activity
AOC05_RS06870	COG1136	(ABC) transporter
AOC05_RS06930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOC05_RS06950	COG0656	L-ascorbic acid biosynthetic process
AOC05_RS06955	COG1968	undecaprenyl-diphosphatase activity
AOC05_RS06960	COG0215	cysteine-tRNA ligase activity
AOC05_RS06970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOC05_RS06985	COG1222	aaa ATPase
AOC05_RS06990	COG4122	O-methyltransferase activity
AOC05_RS07000	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AOC05_RS07005	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AOC05_RS07010	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AOC05_RS07035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOC05_RS07040	COG0805	protein transport
AOC05_RS07045	COG4581	dead DEAH box helicase
AOC05_RS07055	COG1216	Glycosyl transferase, family 2
AOC05_RS07080	COG2364	Membrane
AOC05_RS07085	COG2226	methyltransferase
AOC05_RS07090	COG0242	peptide deformylase activity
AOC05_RS07095	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOC05_RS07100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOC05_RS07105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOC05_RS07145	COG0494	nUDIX hydrolase
AOC05_RS07175	COG4644	lycopene metabolic process
AOC05_RS07180	COG1129	ABC transporter
AOC05_RS07200	COG1522	sequence-specific DNA binding
AOC05_RS07205	COG3142	Participates in the control of copper homeostasis
AOC05_RS07210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOC05_RS07215	COG1845	cytochrome c oxidase, subunit III
AOC05_RS07220	COG2010	Cytochrome c
AOC05_RS07225	COG0723	plastoquinol--plastocyanin reductase activity
AOC05_RS07230	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOC05_RS07235	COG2188	Transcriptional regulator
AOC05_RS07250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOC05_RS07255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOC05_RS07275	COG0667	Aldo Keto reductase
AOC05_RS07280	COG0167	dihydroorotate dehydrogenase activity
AOC05_RS07300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOC05_RS07305	COG1381	Involved in DNA repair and RecF pathway recombination
AOC05_RS07310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOC05_RS07315	COG3590	peptidase
AOC05_RS07325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOC05_RS07335	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AOC05_RS07350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOC05_RS07355	COG0484	heat shock protein binding
AOC05_RS07360	COG1420	regulation of RNA biosynthetic process
AOC05_RS07375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOC05_RS07380	COG0481	GTPase activity
AOC05_RS07390	COG0268	Binds directly to 16S ribosomal RNA
AOC05_RS07410	COG1307	EDD domain protein, DegV family
AOC05_RS07415	COG0495	leucyl-tRNA aminoacylation
AOC05_RS07420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOC05_RS07425	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AOC05_RS07430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOC05_RS07435	COG2390	Transcriptional regulator
AOC05_RS07440	COG0656	L-ascorbic acid biosynthetic process
AOC05_RS07480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOC05_RS07485	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AOC05_RS07495	COG1758	RNA polymerase activity
AOC05_RS07500	COG0194	GDP metabolic process
AOC05_RS07505	COG0194	GDP metabolic process
AOC05_RS07510	COG0284	orotidine-5'-phosphate decarboxylase activity
AOC05_RS07515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AOC05_RS07520	COG0505	Belongs to the CarA family
AOC05_RS07530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AOC05_RS07535	COG0540	Belongs to the ATCase OTCase family
AOC05_RS07540	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AOC05_RS07550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOC05_RS07555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AOC05_RS07565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AOC05_RS07570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AOC05_RS07575	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AOC05_RS07580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOC05_RS07585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOC05_RS07590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AOC05_RS07595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOC05_RS07610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AOC05_RS07640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AOC05_RS07645	COG0124	histidyl-tRNA synthetase
AOC05_RS07655	COG1196	nuclear chromosome segregation
AOC05_RS07665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOC05_RS07670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOC05_RS07675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOC05_RS07685	COG2255	four-way junction helicase activity
AOC05_RS07690	COG0632	four-way junction helicase activity
AOC05_RS07695	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AOC05_RS07700	COG0217	transcriptional regulatory protein
AOC05_RS07705	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AOC05_RS07710	COG0367	asparagine synthase
AOC05_RS07730	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AOC05_RS07735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOC05_RS07745	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOC05_RS07750	COG0587	DNA-directed DNA polymerase activity
AOC05_RS07760	COG0456	acetyltransferase
AOC05_RS07765	COG1316	TRANSCRIPTIONal
AOC05_RS07775	COG2135	peptidase activity
AOC05_RS07810	COG0318	PFAM AMP-dependent synthetase and ligase
AOC05_RS07825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOC05_RS07830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOC05_RS07835	COG1780	Probably involved in ribonucleotide reductase function
AOC05_RS07850	COG0583	DNA-binding transcription factor activity
AOC05_RS07860	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS07905	COG0714	Associated with various cellular activities
AOC05_RS07930	COG3012	SEC-C Motif Domain Protein
AOC05_RS07955	COG0799	negative regulation of ribosome biogenesis
AOC05_RS07965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AOC05_RS07975	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AOC05_RS07980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOC05_RS07985	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AOC05_RS07995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AOC05_RS08000	COG0352	thiamine-phosphate diphosphorylase activity
AOC05_RS08000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOC05_RS08000	COG0351	phosphomethylpyrimidine kinase
AOC05_RS08005	COG1530	ribonuclease E activity
AOC05_RS08015	COG0105	UTP biosynthetic process
AOC05_RS08025	COG0285	dihydrofolate synthase activity
AOC05_RS08030	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOC05_RS08040	COG3189	MarR family transcriptional regulator
AOC05_RS08050	COG0525	valine-tRNA ligase activity
AOC05_RS08065	COG0477	Major facilitator Superfamily
AOC05_RS08070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOC05_RS08075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AOC05_RS08080	COG0740	serine-type endopeptidase activity
AOC05_RS08085	COG0740	serine-type endopeptidase activity
AOC05_RS08090	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOC05_RS08110	COG0698	ribose 5-phosphate isomerase
AOC05_RS08135	COG0668	transmembrane transport
AOC05_RS08155	COG1946	Acyl-CoA thioesterase
AOC05_RS08185	COG2985	domain, Protein
AOC05_RS08190	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOC05_RS08200	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AOC05_RS08205	COG0549	Belongs to the carbamate kinase family
AOC05_RS08215	COG0477	Major facilitator Superfamily
AOC05_RS08270	COG2226	methyltransferase
AOC05_RS08330	COG3328	transposase activity
AOC05_RS08355	COG0477	Major facilitator Superfamily
AOC05_RS08360	COG0583	DNA-binding transcription factor activity
AOC05_RS08380	COG0702	epimerase
AOC05_RS08395	COG0415	Belongs to the DNA photolyase family
AOC05_RS08400	COG0415	Belongs to the DNA photolyase family
AOC05_RS08435	COG1022	Amp-dependent synthetase and ligase
AOC05_RS08445	COG0667	Aldo Keto reductase
AOC05_RS08470	COG5433	transposase activity
AOC05_RS08495	COG2217	Heavy metal translocating P-type atpase
AOC05_RS08525	COG3237	CsbD-like
AOC05_RS08535	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AOC05_RS08545	COG2826	transposase and inactivated derivatives, IS30 family
AOC05_RS08605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOC05_RS08615	COG3547	Transposase (IS116 IS110 IS902 family)
AOC05_RS08625	COG2197	response regulator
AOC05_RS08640	COG1191	sigma factor activity
AOC05_RS08655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOC05_RS08705	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS08710	COG0473	3-isopropylmalate dehydrogenase activity
AOC05_RS08715	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOC05_RS08725	COG0531	amino acid
AOC05_RS08735	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS08765	COG1764	response to oxidative stress
AOC05_RS08770	COG1846	Transcriptional regulator
AOC05_RS08780	COG1064	alcohol dehydrogenase
AOC05_RS08795	COG5492	domain, Protein
AOC05_RS08795	COG4932	domain protein
AOC05_RS08800	COG2132	Multicopper oxidase
AOC05_RS08800	COG2132	Multicopper oxidase
AOC05_RS08810	COG5002	protein histidine kinase activity
AOC05_RS08815	COG0745	RESPONSE REGULATOR receiver
AOC05_RS08820	COG2801	Transposase and inactivated derivatives
AOC05_RS08825	COG1937	Protein conserved in bacteria
AOC05_RS08845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOC05_RS08855	COG0659	secondary active sulfate transmembrane transporter activity
AOC05_RS08860	COG0789	Transcriptional regulator
AOC05_RS08900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOC05_RS08905	COG1854	S-ribosylhomocysteine lyase activity
AOC05_RS08950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOC05_RS08955	COG0798	PFAM Bile acid sodium symporter
AOC05_RS08970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOC05_RS08990	COG0076	glutamate decarboxylase activity
AOC05_RS08995	COG2890	protein-(glutamine-N5) methyltransferase activity
AOC05_RS09050	COG0242	peptide deformylase activity
AOC05_RS09055	COG0477	Major facilitator Superfamily
AOC05_RS09065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AOC05_RS09100	COG2197	response regulator
AOC05_RS09105	COG4585	Histidine kinase
AOC05_RS09135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOC05_RS09140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOC05_RS09150	COG1045	serine acetyltransferase
AOC05_RS09155	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOC05_RS09165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOC05_RS09180	COG2176	DNA-directed DNA polymerase activity
AOC05_RS09205	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AOC05_RS09220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOC05_RS09225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOC05_RS09230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOC05_RS09240	COG4974	Belongs to the 'phage' integrase family
AOC05_RS09250	COG0659	secondary active sulfate transmembrane transporter activity
AOC05_RS09260	COG0758	DNA mediated transformation
AOC05_RS09260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOC05_RS09270	COG0792	nuclease activity
AOC05_RS09280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AOC05_RS09290	COG0681	Belongs to the peptidase S26 family
AOC05_RS09295	COG0335	large ribosomal subunit rRNA binding
AOC05_RS09300	COG0336	Belongs to the RNA methyltransferase TrmD family
AOC05_RS09305	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOC05_RS09310	COG1837	Belongs to the UPF0109 family
AOC05_RS09315	COG0228	four-way junction DNA binding
AOC05_RS09325	COG2514	catechol 2,3-dioxygenase activity
AOC05_RS09345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AOC05_RS09370	COG0477	Major facilitator Superfamily
AOC05_RS09380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOC05_RS09385	COG0318	PFAM AMP-dependent synthetase and ligase
AOC05_RS09390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOC05_RS09415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOC05_RS09420	COG0571	ribonuclease III activity
AOC05_RS09425	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AOC05_RS09435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOC05_RS09445	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AOC05_RS09450	COG0300	oxidoreductase activity
AOC05_RS09470	COG2268	Band 7 protein
AOC05_RS09475	COG0742	ribosomal rna small subunit methyltransferase
AOC05_RS09485	COG1461	Dihydroxyacetone kinase
AOC05_RS09505	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AOC05_RS09510	COG1316	TRANSCRIPTIONal
AOC05_RS09520	COG2813	Specifically methylates the guanine in position
AOC05_RS09525	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOC05_RS09530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AOC05_RS09540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AOC05_RS09550	COG0066	3-isopropylmalate dehydratase activity
AOC05_RS09555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AOC05_RS09560	COG1414	Transcriptional regulator
AOC05_RS09595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOC05_RS09610	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOC05_RS09615	COG2116	formate transmembrane transporter activity
AOC05_RS09630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOC05_RS09635	COG0473	3-isopropylmalate dehydrogenase activity
AOC05_RS09640	COG0415	Belongs to the DNA photolyase family
AOC05_RS09665	COG1562	ergosterol biosynthetic process
AOC05_RS09685	COG4585	Histidine kinase
AOC05_RS09690	COG2197	response regulator
AOC05_RS09700	COG1175	transmembrane transport
AOC05_RS09705	COG1653	transport
AOC05_RS09725	COG1136	(ABC) transporter
AOC05_RS09750	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AOC05_RS09755	COG0440	acetolactate synthase activity
AOC05_RS09760	COG0028	Belongs to the TPP enzyme family
AOC05_RS09765	COG0129	dihydroxy-acid dehydratase activity
AOC05_RS09790	COG0747	negative chemotaxis
AOC05_RS09795	COG0579	oxidoreductase
AOC05_RS09800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOC05_RS09810	COG2814	Major facilitator Superfamily
AOC05_RS09815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOC05_RS09845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOC05_RS09860	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AOC05_RS09865	COG3639	organic phosphonate transmembrane transporter activity
AOC05_RS09870	COG3639	organic phosphonate transmembrane transporter activity
AOC05_RS09885	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOC05_RS09915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOC05_RS09920	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOC05_RS09930	COG1113	amino acid transport
AOC05_RS09965	COG0419	ATPase involved in DNA repair
AOC05_RS09970	COG0420	3'-5' exonuclease activity
AOC05_RS09975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AOC05_RS09985	COG2149	membrane
AOC05_RS10010	COG1122	ATPase activity
AOC05_RS10020	COG0586	Pfam SNARE associated Golgi protein
AOC05_RS10025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AOC05_RS10030	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AOC05_RS10045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOC05_RS10055	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOC05_RS10060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AOC05_RS10065	COG1335	isochorismatase
AOC05_RS10080	COG0363	glucosamine-6-phosphate deaminase activity
AOC05_RS10095	COG3118	belongs to the thioredoxin family
AOC05_RS10105	COG0628	permease
AOC05_RS10120	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AOC05_RS10125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AOC05_RS10135	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AOC05_RS10140	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOC05_RS10150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AOC05_RS10155	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AOC05_RS10160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AOC05_RS10165	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AOC05_RS10170	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOC05_RS10175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOC05_RS10180	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOC05_RS10185	COG0356	it plays a direct role in the translocation of protons across the membrane
AOC05_RS10230	COG2890	protein-(glutamine-N5) methyltransferase activity
AOC05_RS10235	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AOC05_RS10245	COG0083	homoserine kinase activity
AOC05_RS10250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOC05_RS10255	COG0460	homoserine dehydrogenase
AOC05_RS10260	COG0019	diaminopimelate decarboxylase activity
AOC05_RS10265	COG0018	arginyl-trna synthetase
AOC05_RS10280	COG2723	6-phospho-beta-galactosidase activity
AOC05_RS10300	COG2813	Specifically methylates the guanine in position
AOC05_RS10320	COG1643	Atp-dependent helicase
AOC05_RS10335	COG0318	PFAM AMP-dependent synthetase and ligase
AOC05_RS10340	COG0537	adenosine 5'-monophosphoramidase activity
AOC05_RS10345	COG1064	alcohol dehydrogenase
AOC05_RS10355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOC05_RS10360	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AOC05_RS10380	COG1120	ATPase activity
AOC05_RS10410	COG3265	gluconokinase activity
AOC05_RS10415	COG3265	gluconokinase activity
AOC05_RS10420	COG4948	Mandelate Racemase Muconate Lactonizing
AOC05_RS10425	COG0246	Mannitol dehydrogenase
AOC05_RS10430	COG1904	glucuronate isomerase
AOC05_RS10435	COG1609	Transcriptional regulator
AOC05_RS10440	COG0673	inositol 2-dehydrogenase activity
AOC05_RS10450	COG0673	inositol 2-dehydrogenase activity
AOC05_RS10460	COG1609	Transcriptional regulator
AOC05_RS10470	COG1175	transmembrane transport
AOC05_RS10475	COG0395	ABC-type sugar transport system, permease component
AOC05_RS10485	COG0567	Dehydrogenase, E1 component
AOC05_RS10485	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOC05_RS10525	COG1595	DNA-templated transcription, initiation
AOC05_RS10535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOC05_RS10545	COG0483	inositol monophosphate 1-phosphatase activity
AOC05_RS10610	COG1472	Belongs to the glycosyl hydrolase 3 family
AOC05_RS10625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AOC05_RS10640	COG2177	Part of the ABC transporter FtsEX involved in
AOC05_RS10645	COG2884	Cell division ATP-binding protein ftsE
AOC05_RS10650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AOC05_RS10690	COG0438	transferase activity, transferring glycosyl groups
AOC05_RS10735	COG0673	inositol 2-dehydrogenase activity
AOC05_RS10755	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AOC05_RS10765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOC05_RS10790	COG0579	oxidoreductase
AOC05_RS10805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOC05_RS10810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOC05_RS10820	COG0463	Glycosyl transferase, family 2
AOC05_RS10855	COG1216	Glycosyl transferase, family 2
AOC05_RS10865	COG1674	ftsk spoiiie
AOC05_RS10885	COG2902	Dehydrogenase
AOC05_RS10920	COG0653	protein targeting
AOC05_RS10925	COG3214	Protein conserved in bacteria
AOC05_RS10930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AOC05_RS10940	COG5401	PFAM Sporulation and spore germination
AOC05_RS10945	COG5000	phosphorelay sensor kinase activity
AOC05_RS10945	COG5002	protein histidine kinase activity
AOC05_RS10950	COG0745	RESPONSE REGULATOR receiver
AOC05_RS10970	COG0714	Associated with various cellular activities
AOC05_RS11000	COG4172	Belongs to the ABC transporter superfamily
AOC05_RS11005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOC05_RS11010	COG0601	transmembrane transport
AOC05_RS11025	COG0482	sulfurtransferase activity
AOC05_RS11040	COG0302	gtp cyclohydrolase
AOC05_RS11050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOC05_RS11075	COG0484	heat shock protein binding
AOC05_RS11080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOC05_RS11090	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOC05_RS11095	COG2086	electron transfer activity
AOC05_RS11100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOC05_RS11110	COG1842	Phage shock protein A
AOC05_RS11115	COG0656	L-ascorbic acid biosynthetic process
AOC05_RS11125	COG0667	Aldo Keto reductase
AOC05_RS11135	COG3585	molybdate ion transport
AOC05_RS11180	COG0251	oxidation-reduction process
AOC05_RS11230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOC05_RS11240	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AOC05_RS11245	COG0028	Belongs to the TPP enzyme family
AOC05_RS11260	COG1024	Enoyl-CoA hydratase
AOC05_RS11270	COG1024	Enoyl-CoA hydratase
AOC05_RS11285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOC05_RS11305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOC05_RS11310	COG0318	PFAM AMP-dependent synthetase and ligase
AOC05_RS11315	COG1024	Enoyl-CoA hydratase
AOC05_RS11320	COG1024	Enoyl-CoA hydratase
AOC05_RS11320	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOC05_RS11325	COG0183	Belongs to the thiolase family
AOC05_RS11330	COG1960	acyl-CoA dehydrogenase activity
AOC05_RS11335	COG1024	Enoyl-CoA hydratase
AOC05_RS11345	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS11350	COG0318	PFAM AMP-dependent synthetase and ligase
AOC05_RS11355	COG1024	Enoyl-CoA hydratase
AOC05_RS11370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOC05_RS11400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOC05_RS11410	COG1615	UPF0182 protein
AOC05_RS11415	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AOC05_RS11460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOC05_RS11500	COG0210	DNA helicase
AOC05_RS11520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOC05_RS11525	COG0765	amino acid transport
AOC05_RS11550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AOC05_RS11565	COG0181	hydroxymethylbilane synthase activity
AOC05_RS11570	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOC05_RS11575	COG3253	May function as heme-dependent peroxidase
AOC05_RS11585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AOC05_RS11590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AOC05_RS11620	COG2154	pterin-4-alpha-carbinolamine dehydratase
AOC05_RS11625	COG2022	thiamine diphosphate biosynthetic process
AOC05_RS11635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOC05_RS11640	COG0352	thiamine-phosphate diphosphorylase activity
AOC05_RS11665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AOC05_RS11675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOC05_RS11680	COG2072	flavoprotein involved in K transport
AOC05_RS11710	COG0842	Transport permease protein
AOC05_RS11710	COG1129	ABC transporter
AOC05_RS11745	COG2755	lipolytic protein G-D-S-L family
AOC05_RS11745	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AOC05_RS11755	COG0006	proline dipeptidase activity
AOC05_RS11765	COG2239	Acts as a magnesium transporter
AOC05_RS11785	COG1595	DNA-templated transcription, initiation
AOC05_RS11790	COG4122	O-methyltransferase activity
AOC05_RS11800	COG0519	Catalyzes the synthesis of GMP from XMP
AOC05_RS11815	COG1126	abc transporter atp-binding protein
AOC05_RS11820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOC05_RS11825	COG0765	amino acid transport
AOC05_RS11830	COG0765	amino acid transport
AOC05_RS11835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOC05_RS11860	COG2171	N-acyltransferase activity
AOC05_RS11890	COG3226	Transcriptional regulator
AOC05_RS11930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOC05_RS11940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOC05_RS11945	COG0601	transmembrane transport
AOC05_RS11955	COG1217	gtp-binding protein TYPA
AOC05_RS11960	COG4166	transmembrane transport
AOC05_RS12010	COG4221	oxidoreductase activity
AOC05_RS12045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOC05_RS12050	COG0012	GTP binding
AOC05_RS12055	COG1322	Protein conserved in bacteria
AOC05_RS12060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AOC05_RS12070	COG1570	exodeoxyribonuclease VII activity
AOC05_RS12075	COG1722	exodeoxyribonuclease VII activity
AOC05_RS12080	COG2326	polyphosphate kinase activity
AOC05_RS12100	COG1609	Transcriptional regulator
AOC05_RS12105	COG2971	BadF BadG BcrA BcrD
AOC05_RS12115	COG2814	Major facilitator Superfamily
AOC05_RS12120	COG0626	cystathionine gamma-synthase activity
AOC05_RS12140	COG0598	Magnesium transport protein CorA
AOC05_RS12150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AOC05_RS12160	COG0156	8-amino-7-oxononanoate synthase activity
AOC05_RS12165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOC05_RS12170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AOC05_RS12185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOC05_RS12190	COG0477	Major facilitator Superfamily
AOC05_RS12195	COG0778	Nitroreductase
AOC05_RS12210	COG0039	L-malate dehydrogenase activity
AOC05_RS12220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOC05_RS12225	COG1309	transcriptional regulator
AOC05_RS12230	COG1131	(ABC) transporter
AOC05_RS12235	COG3559	Exporter of polyketide antibiotics
AOC05_RS12245	COG0412	Dienelactone hydrolase
AOC05_RS12260	COG0488	(ABC) transporter
AOC05_RS12280	COG2217	Heavy metal translocating P-type atpase
AOC05_RS12285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOC05_RS12305	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOC05_RS12315	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOC05_RS12320	COG0509	glycine decarboxylation via glycine cleavage system
AOC05_RS12325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AOC05_RS12330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOC05_RS12330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOC05_RS12335	COG1113	amino acid transport
AOC05_RS12360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOC05_RS12385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOC05_RS12395	COG3711	transcriptional antiterminator
AOC05_RS12400	COG2190	(PTS) system
AOC05_RS12400	COG1263	PTS System
AOC05_RS12400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOC05_RS12405	COG1263	PTS System
AOC05_RS12405	COG2190	(PTS) system
AOC05_RS12405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOC05_RS12410	COG0135	phosphoribosylanthranilate isomerase activity
AOC05_RS12440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOC05_RS12445	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOC05_RS12470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOC05_RS12470	COG0519	Catalyzes the synthesis of GMP from XMP
AOC05_RS12490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOC05_RS12495	COG0516	GMP reductase activity
AOC05_RS12515	COG2217	Heavy metal translocating P-type atpase
AOC05_RS12520	COG0459	protein refolding
AOC05_RS12525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AOC05_RS12530	COG1131	(ABC) transporter
AOC05_RS12540	COG4604	ABC transporter, ATP-binding protein
AOC05_RS12545	COG4605	iron ion homeostasis
AOC05_RS12550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOC05_RS12555	COG4607	ABC-type enterochelin transport system periplasmic component
AOC05_RS12565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOC05_RS12570	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOC05_RS12575	COG0671	phosphoesterase, PA-phosphatase related
AOC05_RS12580	COG0586	Pfam SNARE associated Golgi protein
AOC05_RS12590	COG5002	protein histidine kinase activity
AOC05_RS12595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AOC05_RS12610	COG0802	atpase or kinase
AOC05_RS12615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOC05_RS12620	COG0438	transferase activity, transferring glycosyl groups
AOC05_RS12630	COG0366	Alpha amylase catalytic
AOC05_RS12640	COG1260	myo-inositol-1-phosphate synthase
AOC05_RS12645	COG0667	Aldo Keto reductase
AOC05_RS12660	COG0736	holo-[acyl-carrier-protein] synthase activity
AOC05_RS12665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOC05_RS12670	COG1072	(Pantothenic acid kinase))
AOC05_RS12680	COG1970	mechanosensitive ion channel activity
AOC05_RS12685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOC05_RS12690	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOC05_RS12695	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AOC05_RS12700	COG0101	tRNA pseudouridine synthase activity
AOC05_RS12705	COG0203	ribosomal protein L17
AOC05_RS12710	COG0202	RNA polymerase activity
AOC05_RS12715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AOC05_RS12720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AOC05_RS12725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AOC05_RS12730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOC05_RS12735	COG3191	aminopeptidase activity
AOC05_RS12750	COG1175	transmembrane transport
AOC05_RS12755	COG0584	glycerophosphoryl diester phosphodiesterase
AOC05_RS12760	COG0024	Methionine aminopeptidase
AOC05_RS12765	COG0563	adenylate kinase activity
AOC05_RS12775	COG0200	Binds to the 23S rRNA
AOC05_RS12780	COG1841	ribosomal large subunit assembly
AOC05_RS12785	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AOC05_RS12795	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AOC05_RS12800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AOC05_RS12805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AOC05_RS12810	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AOC05_RS12815	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AOC05_RS12820	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AOC05_RS12825	COG0255	Belongs to the universal ribosomal protein uL29 family
AOC05_RS12830	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AOC05_RS12835	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AOC05_RS12840	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AOC05_RS12845	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AOC05_RS12850	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AOC05_RS12855	COG0089	rRNA binding
AOC05_RS12860	COG0088	Forms part of the polypeptide exit tunnel
AOC05_RS12865	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AOC05_RS12870	COG0051	transcription antitermination factor activity, RNA binding
AOC05_RS12895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AOC05_RS12900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOC05_RS12905	COG0049	tRNA binding
AOC05_RS12910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AOC05_RS12915	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOC05_RS12920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOC05_RS12925	COG0085	RNA polymerase activity
AOC05_RS12930	COG0183	Belongs to the thiolase family
AOC05_RS12935	COG0222	ribosome binding
AOC05_RS12940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AOC05_RS12955	COG0081	regulation of translation
AOC05_RS12960	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOC05_RS12965	COG0250	Participates in transcription elongation, termination and antitermination
AOC05_RS12980	COG0436	Aminotransferase
AOC05_RS12985	COG2197	response regulator
AOC05_RS13025	COG0354	folic acid binding
AOC05_RS13030	COG3485	protocatechuate 3,4-dioxygenase
AOC05_RS13040	COG0745	RESPONSE REGULATOR receiver
AOC05_RS13045	COG0456	acetyltransferase
AOC05_RS13050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AOC05_RS13070	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AOC05_RS13075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AOC05_RS13095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AOC05_RS13110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOC05_RS13115	COG0738	Major facilitator superfamily
AOC05_RS13120	COG2030	dehydratase
AOC05_RS13125	COG2030	dehydratase
AOC05_RS13135	COG0477	Major facilitator Superfamily
AOC05_RS13150	COG2301	Belongs to the HpcH HpaI aldolase family
AOC05_RS13165	COG0025	NhaP-type Na H and K H
AOC05_RS13195	COG0477	Major facilitator Superfamily
AOC05_RS13215	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AOC05_RS13220	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AOC05_RS13225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AOC05_RS13235	COG0402	S-adenosylhomocysteine deaminase activity
AOC05_RS13240	COG2801	Transposase and inactivated derivatives
AOC05_RS13250	COG1652	LysM domain
AOC05_RS13265	COG4977	sequence-specific DNA binding
AOC05_RS13295	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS13305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AOC05_RS13320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOC05_RS13325	COG2814	Major facilitator Superfamily
AOC05_RS13335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOC05_RS13360	COG1666	GTP binding
AOC05_RS13370	COG2197	response regulator
AOC05_RS13375	COG4585	Histidine kinase
AOC05_RS13380	COG0406	alpha-ribazole phosphatase activity
AOC05_RS13385	COG0501	Belongs to the peptidase M48B family
AOC05_RS13400	COG0753	catalase activity
AOC05_RS13430	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AOC05_RS13435	COG0531	amino acid
AOC05_RS13460	COG0673	inositol 2-dehydrogenase activity
AOC05_RS13475	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS13495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOC05_RS13495	COG1648	precorrin-2 dehydrogenase activity
AOC05_RS13500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOC05_RS13505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AOC05_RS13560	COG0175	sulfate reduction
AOC05_RS13565	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOC05_RS13585	COG4152	abc transporter atp-binding protein
AOC05_RS13590	COG2860	membrane
AOC05_RS13615	COG0142	geranyltranstransferase activity
AOC05_RS13625	COG2226	methyltransferase
AOC05_RS13630	COG1169	isochorismate synthase
AOC05_RS13640	COG0765	amino acid transport
AOC05_RS13645	COG1126	abc transporter atp-binding protein
AOC05_RS13650	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AOC05_RS13655	COG4948	Mandelate Racemase Muconate Lactonizing
AOC05_RS13670	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOC05_RS13690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOC05_RS13705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOC05_RS13710	COG2151	metal-sulfur cluster biosynthetic enzyme
AOC05_RS13715	COG3396	Phenylacetate-CoA oxygenase
AOC05_RS13720	COG3460	Phenylacetate-CoA oxygenase
AOC05_RS13725	COG3396	Phenylacetate-CoA oxygenase
AOC05_RS13730	COG2050	protein possibly involved in aromatic compounds catabolism
AOC05_RS13760	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS13760	COG2030	dehydratase
AOC05_RS13765	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOC05_RS13770	COG1024	Enoyl-CoA hydratase
AOC05_RS13790	COG2211	Major facilitator Superfamily
AOC05_RS13795	COG0076	glutamate decarboxylase activity
AOC05_RS13800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOC05_RS13805	COG0857	belongs to the CobB CobQ family
AOC05_RS13805	COG0280	phosphate acetyltransferase
AOC05_RS13850	COG0653	protein targeting
AOC05_RS13865	COG2365	Tyrosine phosphatase family
AOC05_RS13875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AOC05_RS13910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOC05_RS13915	COG1333	cytochrome c biogenesis protein
AOC05_RS13920	COG0785	Cytochrome C biogenesis protein
AOC05_RS13925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOC05_RS13930	COG0406	alpha-ribazole phosphatase activity
AOC05_RS13945	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AOC05_RS13965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOC05_RS13970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOC05_RS13975	COG1070	Carbohydrate kinase
AOC05_RS13980	COG3347	Dehydrogenase
AOC05_RS13980	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS13990	COG3254	rhamnose metabolic process
AOC05_RS14000	COG1879	ABC-type sugar transport system periplasmic component
AOC05_RS14010	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOC05_RS14015	COG1129	ABC transporter
AOC05_RS14020	COG1609	Transcriptional regulator
AOC05_RS14025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOC05_RS14030	COG0640	Transcriptional regulator
AOC05_RS14035	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOC05_RS14040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOC05_RS14045	COG0569	domain protein
AOC05_RS14050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOC05_RS14055	COG1595	DNA-templated transcription, initiation
AOC05_RS14060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOC05_RS14060	COG2169	Transcriptional regulator
AOC05_RS14065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOC05_RS14070	COG1082	Xylose isomerase domain protein TIM barrel
AOC05_RS14075	COG0248	Ppx GppA phosphatase
AOC05_RS14080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOC05_RS14080	COG1754	DNA topoisomerase type I activity
AOC05_RS14090	COG2890	protein-(glutamine-N5) methyltransferase activity
AOC05_RS14095	COG1054	Belongs to the UPF0176 family
AOC05_RS14105	COG1111	helicase
AOC05_RS14105	COG1205	dead DEAH box helicase
AOC05_RS14170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOC05_RS14175	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AOC05_RS14200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOC05_RS14205	COG1408	metallophosphoesterase
AOC05_RS14210	COG1132	(ABC) transporter
AOC05_RS14215	COG1132	(ABC) transporter
AOC05_RS14225	COG2824	Alkylphosphonate utilization operon protein PhnA
AOC05_RS14240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AOC05_RS14245	COG0151	Belongs to the GarS family
AOC05_RS14275	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AOC05_RS14290	COG0542	response to heat
AOC05_RS14295	COG1063	alcohol dehydrogenase
AOC05_RS14305	COG2226	methyltransferase
AOC05_RS14340	COG3304	Inner membrane component domain
AOC05_RS14370	COG2197	response regulator
AOC05_RS14385	COG0475	glutathione-regulated potassium exporter activity
AOC05_RS14385	COG0569	domain protein
AOC05_RS14395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOC05_RS14405	COG1140	nitrate reductase beta subunit
AOC05_RS14425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOC05_RS14430	COG0789	Transcriptional regulator
AOC05_RS14435	COG0484	heat shock protein binding
AOC05_RS14440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOC05_RS14445	COG0443	Heat shock 70 kDa protein
AOC05_RS14460	COG1280	lysine exporter protein (LysE YggA)
AOC05_RS14465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOC05_RS14475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOC05_RS14490	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOC05_RS14495	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AOC05_RS14525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AOC05_RS14535	COG1122	ATPase activity
AOC05_RS14540	COG4721	ABC-type cobalt transport system, permease component
AOC05_RS14550	COG1320	monovalent cation:proton antiporter activity
AOC05_RS14555	COG2212	antiporter activity
AOC05_RS14565	COG0651	ATP synthesis coupled electron transport
AOC05_RS14570	COG1006	Multisubunit Na H antiporter MnhC subunit
AOC05_RS14575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOC05_RS14575	COG2111	Na H antiporter
AOC05_RS14585	COG0717	Belongs to the dCTP deaminase family
AOC05_RS14595	COG0475	glutathione-regulated potassium exporter activity
AOC05_RS14630	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AOC05_RS14650	COG0433	COG0433 Predicted ATPase
AOC05_RS14665	COG1276	copper resistance
AOC05_RS14665	COG2372	response to copper ion
AOC05_RS14670	COG0776	regulation of translation
AOC05_RS14675	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AOC05_RS14680	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AOC05_RS14685	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AOC05_RS14705	COG1132	(ABC) transporter
AOC05_RS14715	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AOC05_RS14720	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AOC05_RS14730	COG1120	ATPase activity
AOC05_RS14735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOC05_RS14740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOC05_RS14750	COG0435	Glutathione S-transferase
AOC05_RS14755	COG0517	IMP dehydrogenase activity
AOC05_RS14755	COG1125	glycine betaine transport
AOC05_RS14760	COG1174	glycine betaine transport
AOC05_RS14830	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS14910	COG0745	RESPONSE REGULATOR receiver
AOC05_RS14935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOC05_RS14940	COG1120	ATPase activity
AOC05_RS14960	COG0673	inositol 2-dehydrogenase activity
AOC05_RS14980	COG0686	Belongs to the AlaDH PNT family
AOC05_RS14995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOC05_RS15015	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOC05_RS15020	COG0022	dehydrogenase e1 component
AOC05_RS15030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOC05_RS15035	COG1950	PFAM Membrane protein of
AOC05_RS15050	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOC05_RS15065	COG1607	acyl-coa hydrolase
AOC05_RS15070	COG0436	Aminotransferase
AOC05_RS15090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AOC05_RS15100	COG0028	Belongs to the TPP enzyme family
AOC05_RS15110	COG2213	PTS system mannitol-specific
AOC05_RS15120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOC05_RS15130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AOC05_RS15140	COG1937	Protein conserved in bacteria
AOC05_RS15165	COG0395	ABC-type sugar transport system, permease component
AOC05_RS15170	COG1175	transmembrane transport
AOC05_RS15175	COG1653	transport
AOC05_RS15180	COG4821	SIS domain
AOC05_RS15225	COG0359	binds to the 23S rRNA
AOC05_RS15230	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AOC05_RS15240	COG0360	Binds together with S18 to 16S ribosomal RNA
AOC05_RS15250	COG1362	aminopeptidase activity
AOC05_RS15255	COG2197	response regulator
AOC05_RS15260	COG4585	Histidine kinase
AOC05_RS15280	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOC05_RS15290	COG0738	Major facilitator superfamily
AOC05_RS15295	COG0488	(ABC) transporter
AOC05_RS15310	COG2197	response regulator
AOC05_RS15315	COG3883	PFAM NLP P60 protein
AOC05_RS15315	COG0791	NLP P60 protein
AOC05_RS15330	COG0577	efflux transmembrane transporter activity
AOC05_RS15360	COG0406	alpha-ribazole phosphatase activity
AOC05_RS15385	COG0492	ferredoxin-NADP+ reductase activity
AOC05_RS15390	COG3118	belongs to the thioredoxin family
AOC05_RS15405	COG3547	Transposase (IS116 IS110 IS902 family)
AOC05_RS15410	COG3547	Transposase (IS116 IS110 IS902 family)
AOC05_RS15415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOC05_RS15440	COG1192	Involved in chromosome partitioning
AOC05_RS15445	COG0357	Ribosomal RNA small subunit methyltransferase G
AOC05_RS15455	COG0706	membrane insertase activity
AOC05_RS15460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AOC05_RS15465	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AOC05_RS15470	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AOC05_RS15480	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AOC05_RS15485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AOC05_RS15490	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AOC05_RS15495	COG0187	DNA topoisomerase II activity
AOC05_RS15500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOC05_RS15505	COG3266	domain, Protein
AOC05_RS15535	COG0705	Rhomboid family
AOC05_RS15570	COG0596	Alpha beta hydrolase
AOC05_RS15580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOC05_RS15595	COG3764	Sortase (surface protein transpeptidase)
AOC05_RS15605	COG0515	serine threonine protein kinase
AOC05_RS15610	COG0515	serine threonine protein kinase
AOC05_RS15615	COG0768	penicillin binding
AOC05_RS15630	COG1716	ATPase activity
AOC05_RS15635	COG1716	ATPase activity
AOC05_RS15645	COG2826	transposase and inactivated derivatives, IS30 family
AOC05_RS15685	COG2801	Transposase and inactivated derivatives
AOC05_RS15790	COG3853	Toxic anion resistance protein (TelA)
AOC05_RS15825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOC05_RS15835	COG1522	sequence-specific DNA binding
AOC05_RS15840	COG0247	lactate metabolic process
AOC05_RS15845	COG1139	Iron-sulfur cluster binding protein
AOC05_RS15850	COG1556	Lactate utilization protein
AOC05_RS15870	COG1063	alcohol dehydrogenase
AOC05_RS15875	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AOC05_RS15885	COG4786	Flagellar basal body rod
AOC05_RS15885	COG1256	bacterial-type flagellum assembly
AOC05_RS15900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOC05_RS15920	COG1815	bacterial-type flagellum-dependent cell motility
AOC05_RS15930	COG1677	Flagellar hook-basal body complex protein FliE
AOC05_RS15950	COG1157	protein secretion by the type III secretion system
AOC05_RS15965	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AOC05_RS16005	COG1338	Plays a role in the flagellum-specific transport system
AOC05_RS16020	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AOC05_RS16025	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AOC05_RS16035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AOC05_RS16095	COG2409	Drug exporters of the RND superfamily
AOC05_RS16100	COG0006	proline dipeptidase activity
AOC05_RS16130	COG3938	Belongs to the proline racemase family
AOC05_RS16145	COG2197	response regulator
AOC05_RS16160	COG3938	Belongs to the proline racemase family
AOC05_RS16180	COG1802	Transcriptional regulator
AOC05_RS16220	COG0561	phosphatase activity
AOC05_RS16230	COG1929	Belongs to the glycerate kinase type-1 family
AOC05_RS16235	COG2233	PERMEase
AOC05_RS16265	COG3104	oligopeptide transport
AOC05_RS16270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOC05_RS16280	COG1597	lipid kinase activity
AOC05_RS16285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AOC05_RS16290	COG0561	phosphatase activity
AOC05_RS16325	COG2027	D-alanyl-D-alanine carboxypeptidase
AOC05_RS16335	COG0037	tRNA processing
AOC05_RS16345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOC05_RS16350	COG0302	gtp cyclohydrolase
AOC05_RS16360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOC05_RS16390	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AOC05_RS16395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOC05_RS16400	COG0477	Major facilitator Superfamily
AOC05_RS16410	COG1609	Transcriptional regulator
AOC05_RS16415	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOC05_RS16430	COG3548	integral membrane protein
AOC05_RS16440	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AOC05_RS16445	COG2376	Dihydroxyacetone kinase
AOC05_RS16450	COG1461	Dihydroxyacetone kinase
AOC05_RS16455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOC05_RS16455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOC05_RS16455	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AOC05_RS16470	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AOC05_RS16490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOC05_RS16505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOC05_RS16540	COG1335	isochorismatase
AOC05_RS16545	COG0351	phosphomethylpyrimidine kinase
AOC05_RS16555	COG4221	oxidoreductase activity
AOC05_RS16565	COG0477	Major facilitator Superfamily
AOC05_RS16570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOC05_RS16570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOC05_RS16570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOC05_RS16580	COG1349	DNA-binding transcription factor activity
AOC05_RS16600	COG2733	membrane
AOC05_RS16605	COG0584	glycerophosphoryl diester phosphodiesterase
AOC05_RS16610	COG3387	PFAM Glycoside hydrolase 15-related
AOC05_RS16640	COG4122	O-methyltransferase activity
AOC05_RS16690	COG0010	Belongs to the arginase family
AOC05_RS16695	COG2252	PERMEase
AOC05_RS16700	COG2372	response to copper ion
AOC05_RS16725	COG3883	PFAM NLP P60 protein
AOC05_RS16725	COG0791	NLP P60 protein
AOC05_RS16820	COG0517	IMP dehydrogenase activity
AOC05_RS16820	COG4175	Glycine betaine
AOC05_RS16825	COG4176	ABC-type proline glycine betaine transport system permease component
AOC05_RS16840	COG2801	Transposase and inactivated derivatives
AOC05_RS16845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOC05_RS16850	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOC05_RS16865	COG1175	transmembrane transport
AOC05_RS16870	COG0395	ABC-type sugar transport system, permease component
AOC05_RS16875	COG4948	Mandelate Racemase Muconate Lactonizing
AOC05_RS16890	COG4948	Mandelate Racemase Muconate Lactonizing
AOC05_RS16895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AOC05_RS16900	COG1435	thymidine kinase activity
AOC05_RS16920	COG0191	fructose-bisphosphate aldolase activity
AOC05_RS16950	COG0477	Major facilitator Superfamily
AOC05_RS16965	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS16970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AOC05_RS16975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOC05_RS16985	COG1832	CoA-binding protein
AOC05_RS17010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOC05_RS17015	COG0047	phosphoribosylformylglycinamidine synthase activity
AOC05_RS17020	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOC05_RS17030	COG1846	Transcriptional regulator
AOC05_RS17055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOC05_RS17060	COG2076	Multidrug Resistance protein
AOC05_RS17070	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS17085	COG4555	ABC transporter
AOC05_RS17095	COG0129	dihydroxy-acid dehydratase activity
AOC05_RS17105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOC05_RS17130	COG0386	Belongs to the glutathione peroxidase family
AOC05_RS17150	COG1309	transcriptional regulator
AOC05_RS17200	COG4942	peptidase
AOC05_RS17205	COG4565	transcriptional regulatory protein
AOC05_RS17210	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOC05_RS17230	COG0488	(ABC) transporter
AOC05_RS17250	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AOC05_RS17265	COG1132	(ABC) transporter
AOC05_RS17270	COG1132	(ABC) transporter
AOC05_RS17275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOC05_RS17290	COG0673	inositol 2-dehydrogenase activity
AOC05_RS17295	COG0673	inositol 2-dehydrogenase activity
AOC05_RS17310	COG1609	Transcriptional regulator
AOC05_RS17320	COG1175	transmembrane transport
AOC05_RS17325	COG0395	ABC-type sugar transport system, permease component
AOC05_RS17345	COG3118	belongs to the thioredoxin family
AOC05_RS17345	COG0492	ferredoxin-NADP+ reductase activity
AOC05_RS17360	COG1136	(ABC) transporter
AOC05_RS17375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOC05_RS17385	COG1192	Involved in chromosome partitioning
AOC05_RS17430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOC05_RS17465	COG0477	Major facilitator Superfamily
AOC05_RS17470	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS17480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOC05_RS17485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOC05_RS17500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOC05_RS17510	COG1476	TRANSCRIPTIONal
AOC05_RS17525	COG1960	acyl-CoA dehydrogenase activity
AOC05_RS17560	COG3971	2-oxopent-4-enoate hydratase activity
AOC05_RS17570	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS17575	COG1802	Transcriptional regulator
AOC05_RS17585	COG1522	sequence-specific DNA binding
AOC05_RS17590	COG0028	Belongs to the TPP enzyme family
AOC05_RS17615	COG3226	Transcriptional regulator
AOC05_RS17630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AOC05_RS17660	COG3483	tryptophan 2,3-dioxygenase activity
AOC05_RS17675	COG1473	amidohydrolase
AOC05_RS17675	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOC05_RS17680	COG1737	Transcriptional regulator
AOC05_RS17700	COG0343	queuine tRNA-ribosyltransferase activity
AOC05_RS17730	COG0601	transmembrane transport
AOC05_RS17735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOC05_RS17740	COG4172	Belongs to the ABC transporter superfamily
AOC05_RS17750	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS17755	COG1012	belongs to the aldehyde dehydrogenase family
AOC05_RS17760	COG0473	3-isopropylmalate dehydrogenase activity
AOC05_RS17795	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AOC05_RS17805	COG1302	Protein conserved in bacteria
AOC05_RS17845	COG0564	pseudouridine synthase activity
AOC05_RS17865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOC05_RS17870	COG1201	RNA secondary structure unwinding
AOC05_RS17895	COG2205	protein histidine kinase activity
AOC05_RS17900	COG0745	RESPONSE REGULATOR receiver
AOC05_RS17955	COG3177	Filamentation induced by cAMP protein fic
AOC05_RS17975	COG3177	Filamentation induced by cAMP protein fic
AOC05_RS18000	COG2184	nucleotidyltransferase activity
AOC05_RS18015	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AOC05_RS18020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOC05_RS18110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOC05_RS18205	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS18215	COG0783	Belongs to the Dps family
AOC05_RS18295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AOC05_RS18320	COG2062	phosphohistidine phosphatase, SixA
AOC05_RS18325	COG1511	domain protein
AOC05_RS18340	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AOC05_RS18345	COG1940	carbohydrate kinase activity
AOC05_RS18355	COG4608	Belongs to the ABC transporter superfamily
AOC05_RS18360	COG0444	Belongs to the ABC transporter superfamily
AOC05_RS18375	COG2186	Transcriptional regulator
AOC05_RS18390	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AOC05_RS18400	COG1959	2 iron, 2 sulfur cluster binding
AOC05_RS18415	COG0514	ATP-dependent DNA helicase (RecQ)
AOC05_RS18420	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS18430	COG4948	Mandelate Racemase Muconate Lactonizing
AOC05_RS18460	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOC05_RS18465	COG1879	ABC-type sugar transport system periplasmic component
AOC05_RS18470	COG2186	Transcriptional regulator
AOC05_RS18480	COG1505	serine-type exopeptidase activity
AOC05_RS18495	COG1028	Short-chain dehydrogenase reductase Sdr
AOC05_RS18495	COG3321	synthase
AOC05_RS18495	COG0604	alcohol dehydrogenase
AOC05_RS18500	COG1966	Carbon starvation protein
AOC05_RS18530	COG3842	ATPase activity
AOC05_RS18550	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOC05_RS18555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AOC05_RS18560	COG0626	cystathionine gamma-synthase activity