locus-tag	class	description
ARTH_RS00015	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ARTH_RS00020	COG0592	DNA-directed DNA polymerase activity
ARTH_RS00025	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ARTH_RS00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ARTH_RS00035	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ARTH_RS00040	COG0187	DNA topoisomerase II activity
ARTH_RS00050	COG3266	domain, Protein
ARTH_RS00085	COG0705	Rhomboid family
ARTH_RS00090	COG2818	Glycosylase
ARTH_RS00105	COG3764	Sortase (surface protein transpeptidase)
ARTH_RS00120	COG2815	serine threonine protein kinase
ARTH_RS00120	COG0515	serine threonine protein kinase
ARTH_RS00125	COG0515	serine threonine protein kinase
ARTH_RS00130	COG0768	penicillin binding
ARTH_RS00145	COG1716	ATPase activity
ARTH_RS00150	COG1716	ATPase activity
ARTH_RS00165	COG1116	anion transmembrane transporter activity
ARTH_RS00175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARTH_RS00180	COG1609	Transcriptional regulator
ARTH_RS00200	COG4948	Mandelate Racemase Muconate Lactonizing
ARTH_RS00210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARTH_RS00215	COG0583	DNA-binding transcription factor activity
ARTH_RS00275	COG0395	ABC-type sugar transport system, permease component
ARTH_RS00285	COG1609	Transcriptional regulator
ARTH_RS00290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARTH_RS00295	COG1621	beta-fructofuranosidase activity
ARTH_RS00340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ARTH_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS00390	COG2755	lipolytic protein G-D-S-L family
ARTH_RS00430	COG0586	Pfam SNARE associated Golgi protein
ARTH_RS00435	COG1609	Transcriptional regulator
ARTH_RS00440	COG1957	nucleoside hydrolase
ARTH_RS00445	COG0477	Major facilitator Superfamily
ARTH_RS00450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARTH_RS00470	COG0673	inositol 2-dehydrogenase activity
ARTH_RS00480	COG1175	transmembrane transport
ARTH_RS00495	COG2186	Transcriptional regulator
ARTH_RS00500	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ARTH_RS00505	COG0477	Major facilitator Superfamily
ARTH_RS00510	COG1984	allophanate hydrolase subunit 2
ARTH_RS00515	COG4770	biotin carboxylase activity
ARTH_RS00535	COG3707	response regulator
ARTH_RS00545	COG0385	Bile acid
ARTH_RS00555	COG0659	secondary active sulfate transmembrane transporter activity
ARTH_RS00570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ARTH_RS00575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARTH_RS00575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARTH_RS00590	COG0561	phosphatase activity
ARTH_RS00595	COG0584	glycerophosphoryl diester phosphodiesterase
ARTH_RS00615	COG5002	protein histidine kinase activity
ARTH_RS00625	COG4106	trans-aconitate 2-methyltransferase activity
ARTH_RS00630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ARTH_RS00645	COG2267	carboxylic ester hydrolase activity
ARTH_RS00650	COG1929	Belongs to the glycerate kinase type-1 family
ARTH_RS00665	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS00675	COG2233	PERMEase
ARTH_RS00680	COG0778	Nitroreductase
ARTH_RS00705	COG3104	oligopeptide transport
ARTH_RS00710	COG0154	amidase activity
ARTH_RS00715	COG3340	Belongs to the peptidase S51 family
ARTH_RS00720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARTH_RS00735	COG1597	lipid kinase activity
ARTH_RS00740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ARTH_RS00745	COG0561	phosphatase activity
ARTH_RS00785	COG0037	tRNA processing
ARTH_RS00795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARTH_RS00800	COG0302	gtp cyclohydrolase
ARTH_RS00805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ARTH_RS00810	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ARTH_RS00840	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ARTH_RS00845	COG2814	Major facilitator Superfamily
ARTH_RS00865	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ARTH_RS00885	COG0823	Involved in the tonB-independent uptake of proteins
ARTH_RS00885	COG1506	peptidase
ARTH_RS00890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ARTH_RS00895	COG2376	Dihydroxyacetone kinase
ARTH_RS00900	COG1461	Dihydroxyacetone kinase
ARTH_RS00935	COG0363	glucosamine-6-phosphate deaminase activity
ARTH_RS00940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ARTH_RS00945	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ARTH_RS00950	COG1940	carbohydrate kinase activity
ARTH_RS00955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARTH_RS00960	COG4608	Belongs to the ABC transporter superfamily
ARTH_RS00965	COG0444	Belongs to the ABC transporter superfamily
ARTH_RS00975	COG0747	negative chemotaxis
ARTH_RS00985	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ARTH_RS00990	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ARTH_RS00995	COG2815	serine threonine protein kinase
ARTH_RS00995	COG0515	serine threonine protein kinase
ARTH_RS01020	COG2217	Heavy metal translocating P-type atpase
ARTH_RS01025	COG2132	Multicopper oxidase
ARTH_RS01060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ARTH_RS01065	COG0306	phosphate transporter
ARTH_RS01100	COG0798	PFAM Bile acid sodium symporter
ARTH_RS01105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARTH_RS01110	COG0492	ferredoxin-NADP+ reductase activity
ARTH_RS01120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARTH_RS01130	COG3384	dioxygenase
ARTH_RS01135	COG1609	Transcriptional regulator
ARTH_RS01160	COG2160	L-arabinose isomerase activity
ARTH_RS01165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ARTH_RS01180	COG1609	Transcriptional regulator
ARTH_RS01195	COG2837	iron assimilation
ARTH_RS01210	COG4948	Mandelate Racemase Muconate Lactonizing
ARTH_RS01215	COG1802	Transcriptional regulator
ARTH_RS01220	COG2271	Major facilitator Superfamily
ARTH_RS01230	COG0586	Pfam SNARE associated Golgi protein
ARTH_RS01245	COG0831	urea catabolic process
ARTH_RS01250	COG0832	Belongs to the urease beta subunit family
ARTH_RS01255	COG0804	urea catabolic process
ARTH_RS01260	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ARTH_RS01265	COG0830	nickel cation binding
ARTH_RS01270	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ARTH_RS01275	COG0829	nickel cation binding
ARTH_RS01280	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ARTH_RS01290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ARTH_RS01290	COG0723	plastoquinol--plastocyanin reductase activity
ARTH_RS01305	COG1228	amidohydrolase
ARTH_RS01315	COG1064	alcohol dehydrogenase
ARTH_RS01325	COG2890	protein-(glutamine-N5) methyltransferase activity
ARTH_RS01330	COG0438	transferase activity, transferring glycosyl groups
ARTH_RS01345	COG2261	transglycosylase associated protein
ARTH_RS01350	COG0656	L-ascorbic acid biosynthetic process
ARTH_RS01360	COG0667	Aldo Keto reductase
ARTH_RS01365	COG0656	L-ascorbic acid biosynthetic process
ARTH_RS01380	COG3360	Dodecin
ARTH_RS01390	COG1937	Protein conserved in bacteria
ARTH_RS01395	COG2186	Transcriptional regulator
ARTH_RS01405	COG2084	Dehydrogenase
ARTH_RS01410	COG2610	gluconate transmembrane transporter activity
ARTH_RS01450	COG1366	Belongs to the anti-sigma-factor antagonist family
ARTH_RS01465	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ARTH_RS01480	COG0300	oxidoreductase activity
ARTH_RS01490	COG0477	Major facilitator Superfamily
ARTH_RS01510	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ARTH_RS01530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ARTH_RS01530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ARTH_RS01530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ARTH_RS01535	COG1105	Belongs to the carbohydrate kinase PfkB family
ARTH_RS01540	COG1349	DNA-binding transcription factor activity
ARTH_RS01555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ARTH_RS01565	COG1609	Transcriptional regulator
ARTH_RS01570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARTH_RS01600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ARTH_RS01610	COG1140	nitrate reductase beta subunit
ARTH_RS01630	COG2733	membrane
ARTH_RS01640	COG3559	Exporter of polyketide antibiotics
ARTH_RS01645	COG1131	(ABC) transporter
ARTH_RS01700	COG4122	O-methyltransferase activity
ARTH_RS01705	COG0783	Belongs to the Dps family
ARTH_RS01725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ARTH_RS01730	COG0574	Belongs to the PEP-utilizing enzyme family
ARTH_RS01730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ARTH_RS01795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ARTH_RS01810	COG0438	transferase activity, transferring glycosyl groups
ARTH_RS01815	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ARTH_RS01820	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ARTH_RS01820	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ARTH_RS01825	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS01840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ARTH_RS01840	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ARTH_RS01865	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS01870	COG1280	lysine exporter protein (LysE YggA)
ARTH_RS01910	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ARTH_RS01940	COG0010	Belongs to the arginase family
ARTH_RS01945	COG2252	PERMEase
ARTH_RS01965	COG0574	Belongs to the PEP-utilizing enzyme family
ARTH_RS01965	COG3848	Pyruvate phosphate dikinase
ARTH_RS02000	COG0697	spore germination
ARTH_RS02010	COG0583	DNA-binding transcription factor activity
ARTH_RS02020	COG1796	DNA polymerase
ARTH_RS02020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ARTH_RS02040	COG0589	response to stress
ARTH_RS02055	COG0601	transmembrane transport
ARTH_RS02060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ARTH_RS02065	COG0444	Belongs to the ABC transporter superfamily
ARTH_RS02070	COG4608	Belongs to the ABC transporter superfamily
ARTH_RS02075	COG1621	beta-fructofuranosidase activity
ARTH_RS02095	COG1302	Protein conserved in bacteria
ARTH_RS02120	COG0366	Alpha amylase catalytic
ARTH_RS02145	COG1609	Transcriptional regulator
ARTH_RS02165	COG1024	Enoyl-CoA hydratase
ARTH_RS02180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARTH_RS02185	COG1621	beta-fructofuranosidase activity
ARTH_RS02195	COG0395	ABC-type sugar transport system, permease component
ARTH_RS02200	COG4209	transmembrane transport
ARTH_RS02205	COG1609	Transcriptional regulator
ARTH_RS02210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ARTH_RS02225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARTH_RS02230	COG1960	acyl-CoA dehydrogenase activity
ARTH_RS02235	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ARTH_RS02270	COG0596	Alpha beta hydrolase
ARTH_RS02405	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ARTH_RS02410	COG1278	Cold shock
ARTH_RS02420	COG0574	Belongs to the PEP-utilizing enzyme family
ARTH_RS02420	COG3848	Pyruvate phosphate dikinase
ARTH_RS02430	COG3706	GGDEF domain
ARTH_RS02445	COG4948	Mandelate Racemase Muconate Lactonizing
ARTH_RS02450	COG0395	ABC-type sugar transport system, permease component
ARTH_RS02455	COG1175	transmembrane transport
ARTH_RS02475	COG2197	response regulator
ARTH_RS02480	COG4585	Histidine kinase
ARTH_RS02495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ARTH_RS02520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ARTH_RS02525	COG1609	Transcriptional regulator
ARTH_RS02535	COG1175	transmembrane transport
ARTH_RS02540	COG0395	ABC-type sugar transport system, permease component
ARTH_RS02550	COG0673	inositol 2-dehydrogenase activity
ARTH_RS02560	COG1904	glucuronate isomerase
ARTH_RS02565	COG0246	Mannitol dehydrogenase
ARTH_RS02570	COG4948	Mandelate Racemase Muconate Lactonizing
ARTH_RS02590	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARTH_RS02595	COG0022	dehydrogenase e1 component
ARTH_RS02595	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARTH_RS02600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ARTH_RS02605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARTH_RS02610	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ARTH_RS02640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ARTH_RS02640	COG0357	Ribosomal RNA small subunit methyltransferase G
ARTH_RS02645	COG0191	fructose-bisphosphate aldolase activity
ARTH_RS02665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ARTH_RS02685	COG1136	(ABC) transporter
ARTH_RS02705	COG1832	CoA-binding protein
ARTH_RS02720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARTH_RS02725	COG1832	CoA-binding protein
ARTH_RS02730	COG2315	Protein conserved in bacteria
ARTH_RS02735	COG4762	Protein conserved in bacteria
ARTH_RS02755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ARTH_RS02760	COG0047	phosphoribosylformylglycinamidine synthase activity
ARTH_RS02780	COG1404	Belongs to the peptidase S8 family
ARTH_RS02805	COG1846	Transcriptional regulator
ARTH_RS02830	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ARTH_RS02840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ARTH_RS02840	COG3323	Protein of unknown function (DUF1653)
ARTH_RS02860	COG0386	Belongs to the glutathione peroxidase family
ARTH_RS02865	COG1063	alcohol dehydrogenase
ARTH_RS02870	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ARTH_RS02895	COG1309	transcriptional regulator
ARTH_RS02915	COG0823	Involved in the tonB-independent uptake of proteins
ARTH_RS02925	COG0673	inositol 2-dehydrogenase activity
ARTH_RS02930	COG0673	inositol 2-dehydrogenase activity
ARTH_RS02940	COG0395	ABC-type sugar transport system, permease component
ARTH_RS02965	COG1846	Transcriptional regulator
ARTH_RS02965	COG1940	carbohydrate kinase activity
ARTH_RS02975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ARTH_RS02985	COG1396	sequence-specific DNA binding
ARTH_RS02995	COG0642	Histidine kinase
ARTH_RS03000	COG0745	RESPONSE REGULATOR receiver
ARTH_RS03005	COG0477	Major facilitator Superfamily
ARTH_RS03015	COG0028	Belongs to the TPP enzyme family
ARTH_RS03030	COG0351	phosphomethylpyrimidine kinase
ARTH_RS03040	COG1090	epimerase
ARTH_RS03065	COG0343	queuine tRNA-ribosyltransferase activity
ARTH_RS03095	COG3842	ATPase activity
ARTH_RS03120	COG1960	acyl-CoA dehydrogenase activity
ARTH_RS03140	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ARTH_RS03155	COG0564	pseudouridine synthase activity
ARTH_RS03175	COG2364	Membrane
ARTH_RS03180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ARTH_RS03185	COG1201	RNA secondary structure unwinding
ARTH_RS03190	COG0723	plastoquinol--plastocyanin reductase activity
ARTH_RS03190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ARTH_RS03225	COG0563	adenylate kinase activity
ARTH_RS03260	COG0596	Alpha beta hydrolase
ARTH_RS03270	COG2226	methyltransferase
ARTH_RS03295	COG0438	transferase activity, transferring glycosyl groups
ARTH_RS03305	COG0671	phosphoesterase, PA-phosphatase related
ARTH_RS03310	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ARTH_RS03345	COG2205	protein histidine kinase activity
ARTH_RS03350	COG0745	RESPONSE REGULATOR receiver
ARTH_RS03370	COG2062	phosphohistidine phosphatase, SixA
ARTH_RS03385	COG1309	transcriptional regulator
ARTH_RS03390	COG1511	domain protein
ARTH_RS03405	COG2186	Transcriptional regulator
ARTH_RS03415	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ARTH_RS03440	COG0514	ATP-dependent DNA helicase (RecQ)
ARTH_RS03460	COG1505	serine-type exopeptidase activity
ARTH_RS03485	COG0604	alcohol dehydrogenase
ARTH_RS03495	COG1966	Carbon starvation protein
ARTH_RS03515	COG0656	L-ascorbic acid biosynthetic process
ARTH_RS03535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ARTH_RS03585	COG1842	Phage shock protein A
ARTH_RS03665	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ARTH_RS03670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ARTH_RS03690	COG0588	phosphoglycerate mutase activity
ARTH_RS03700	COG5002	protein histidine kinase activity
ARTH_RS03720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ARTH_RS03725	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ARTH_RS03735	COG0215	cysteine-tRNA ligase activity
ARTH_RS03770	COG0366	Alpha amylase catalytic
ARTH_RS03775	COG0366	Alpha amylase catalytic
ARTH_RS03780	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ARTH_RS03810	COG1609	Transcriptional regulator
ARTH_RS03815	COG0366	Alpha amylase catalytic
ARTH_RS03825	COG1175	transmembrane transport
ARTH_RS03830	COG3833	ABC-type maltose transport systems, permease component
ARTH_RS03835	COG0366	Alpha amylase catalytic
ARTH_RS03840	COG0277	FAD linked oxidase domain protein
ARTH_RS03850	COG3842	ATPase activity
ARTH_RS03905	COG2957	Belongs to the agmatine deiminase family
ARTH_RS03915	COG0783	Belongs to the Dps family
ARTH_RS03920	COG0477	Major facilitator Superfamily
ARTH_RS03930	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ARTH_RS03930	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ARTH_RS03935	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ARTH_RS03940	COG0509	glycine decarboxylation via glycine cleavage system
ARTH_RS03945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARTH_RS03955	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ARTH_RS03960	COG1864	DNA RNA non-specific endonuclease
ARTH_RS03960	COG3591	Belongs to the peptidase S1B family
ARTH_RS03980	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ARTH_RS03995	COG1278	Cold shock
ARTH_RS04005	COG0459	protein refolding
ARTH_RS04015	COG0328	RNA-DNA hybrid ribonuclease activity
ARTH_RS04025	COG2205	protein histidine kinase activity
ARTH_RS04030	COG0745	RESPONSE REGULATOR receiver
ARTH_RS04060	COG1278	Cold shock
ARTH_RS04085	COG0739	heme binding
ARTH_RS04090	COG0791	NLP P60 protein
ARTH_RS04090	COG3103	Sh3 type 3 domain protein
ARTH_RS04090	COG1388	LysM domain
ARTH_RS04095	COG0791	NLP P60 protein
ARTH_RS04095	COG3103	Sh3 type 3 domain protein
ARTH_RS04095	COG1388	LysM domain
ARTH_RS04105	COG0746	molybdenum cofactor guanylyltransferase activity
ARTH_RS04120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ARTH_RS04140	COG0488	(ABC) transporter
ARTH_RS04145	COG1132	(ABC) transporter
ARTH_RS04150	COG0494	nUDIX hydrolase
ARTH_RS04175	COG0483	inositol monophosphate 1-phosphatase activity
ARTH_RS04190	COG0045	succinate-CoA ligase (ADP-forming) activity
ARTH_RS04205	COG0640	Transcriptional regulator
ARTH_RS04215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARTH_RS04225	COG3962	Belongs to the TPP enzyme family
ARTH_RS04240	COG0673	inositol 2-dehydrogenase activity
ARTH_RS04245	COG1082	Xylose isomerase domain protein TIM barrel
ARTH_RS04250	COG2814	Major facilitator Superfamily
ARTH_RS04260	COG2814	Major facilitator Superfamily
ARTH_RS04270	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARTH_RS04280	COG0673	inositol 2-dehydrogenase activity
ARTH_RS04285	COG0673	inositol 2-dehydrogenase activity
ARTH_RS04290	COG3718	enzyme involved in inositol metabolism
ARTH_RS04295	COG2188	Transcriptional regulator
ARTH_RS04300	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ARTH_RS04310	COG2186	Transcriptional regulator
ARTH_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS04350	COG1396	sequence-specific DNA binding
ARTH_RS04365	COG0347	Belongs to the P(II) protein family
ARTH_RS04375	COG0028	Belongs to the TPP enzyme family
ARTH_RS04425	COG1401	restriction endodeoxyribonuclease activity
ARTH_RS04435	COG1309	transcriptional regulator
ARTH_RS04440	COG5002	protein histidine kinase activity
ARTH_RS04445	COG0745	RESPONSE REGULATOR receiver
ARTH_RS04465	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ARTH_RS04465	COG4124	Belongs to the glycosyl hydrolase 26 family
ARTH_RS04480	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ARTH_RS04500	COG1063	alcohol dehydrogenase
ARTH_RS04505	COG1902	pentaerythritol trinitrate reductase activity
ARTH_RS04520	COG2376	Dihydroxyacetone kinase
ARTH_RS04525	COG0698	ribose 5-phosphate isomerase
ARTH_RS04530	COG1250	3-hydroxyacyl-CoA dehydrogenase
ARTH_RS04535	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS04540	COG2271	Major facilitator Superfamily
ARTH_RS04545	COG0149	triose-phosphate isomerase activity
ARTH_RS04610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ARTH_RS04625	COG3583	domain protein
ARTH_RS04635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ARTH_RS04650	COG0667	Aldo Keto reductase
ARTH_RS04665	COG0366	Alpha amylase catalytic
ARTH_RS04690	COG1254	Belongs to the acylphosphatase family
ARTH_RS04720	COG3655	Transcriptional regulator
ARTH_RS04740	COG0477	Major facilitator Superfamily
ARTH_RS04765	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ARTH_RS04820	COG1846	Transcriptional regulator
ARTH_RS04830	COG1253	flavin adenine dinucleotide binding
ARTH_RS04845	COG0584	glycerophosphoryl diester phosphodiesterase
ARTH_RS04875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ARTH_RS04930	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ARTH_RS04935	COG1597	lipid kinase activity
ARTH_RS04945	COG0028	Belongs to the TPP enzyme family
ARTH_RS04955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ARTH_RS04960	COG1113	amino acid transport
ARTH_RS05010	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ARTH_RS05020	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ARTH_RS05105	COG0456	acetyltransferase
ARTH_RS05110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARTH_RS05115	COG0477	Major facilitator Superfamily
ARTH_RS05130	COG2186	Transcriptional regulator
ARTH_RS05170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARTH_RS05175	COG1349	DNA-binding transcription factor activity
ARTH_RS05200	COG2350	Protein conserved in bacteria
ARTH_RS05225	COG1349	DNA-binding transcription factor activity
ARTH_RS05230	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ARTH_RS05235	COG0747	negative chemotaxis
ARTH_RS05240	COG0601	transmembrane transport
ARTH_RS05245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ARTH_RS05250	COG0444	Belongs to the ABC transporter superfamily
ARTH_RS05255	COG4608	Belongs to the ABC transporter superfamily
ARTH_RS05260	COG0667	Aldo Keto reductase
ARTH_RS05265	COG3836	Belongs to the HpcH HpaI aldolase family
ARTH_RS05275	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS05280	COG3540	Alkaline phosphatase
ARTH_RS05335	COG1278	Cold shock
ARTH_RS05350	COG0673	inositol 2-dehydrogenase activity
ARTH_RS05375	COG2072	flavoprotein involved in K transport
ARTH_RS05390	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS05420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ARTH_RS05440	COG2268	Band 7 protein
ARTH_RS05455	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS05470	COG1024	Enoyl-CoA hydratase
ARTH_RS05475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ARTH_RS05480	COG0446	pyridine nucleotide-disulphide oxidoreductase
ARTH_RS05485	COG0477	Major facilitator Superfamily
ARTH_RS05490	COG1396	sequence-specific DNA binding
ARTH_RS05520	COG2271	Major facilitator Superfamily
ARTH_RS05525	COG0138	bifunctional purine biosynthesis protein purh
ARTH_RS05540	COG2838	Isocitrate dehydrogenase
ARTH_RS05560	COG0515	serine threonine protein kinase
ARTH_RS05560	COG2815	serine threonine protein kinase
ARTH_RS05580	COG1136	(ABC) transporter
ARTH_RS05590	COG4213	ABC transporter substrate-binding protein
ARTH_RS05620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ARTH_RS05625	COG0531	amino acid
ARTH_RS05660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ARTH_RS05665	COG1131	(ABC) transporter
ARTH_RS05685	COG0708	Exodeoxyribonuclease III
ARTH_RS05690	COG0180	Tryptophanyl-tRNA synthetase
ARTH_RS05720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ARTH_RS05735	COG2009	succinate dehydrogenase
ARTH_RS05745	COG1473	amidohydrolase
ARTH_RS05745	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARTH_RS05750	COG1846	Transcriptional regulator
ARTH_RS05755	COG1764	response to oxidative stress
ARTH_RS05760	COG2130	NADP-dependent
ARTH_RS05765	COG1744	ABC transporter substrate-binding protein PnrA-like
ARTH_RS05770	COG3845	ABC transporter
ARTH_RS05775	COG4603	Belongs to the binding-protein-dependent transport system permease family
ARTH_RS05780	COG1079	Belongs to the binding-protein-dependent transport system permease family
ARTH_RS05800	COG0586	Pfam SNARE associated Golgi protein
ARTH_RS05805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ARTH_RS05810	COG3956	TIGRFAM MazG family protein
ARTH_RS05815	COG0148	phosphopyruvate hydratase activity
ARTH_RS05840	COG1252	NADH dehydrogenase
ARTH_RS05885	COG0183	Belongs to the thiolase family
ARTH_RS05890	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ARTH_RS05900	COG2017	converts alpha-aldose to the beta-anomer
ARTH_RS05910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ARTH_RS05920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ARTH_RS05930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ARTH_RS05940	COG1331	Highly conserved protein containing a thioredoxin domain
ARTH_RS05950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ARTH_RS05955	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ARTH_RS05985	COG1309	transcriptional regulator
ARTH_RS05990	COG0114	fumarate hydratase activity
ARTH_RS05995	COG0288	reversible hydration of carbon dioxide
ARTH_RS06005	COG1494	fructose-1,6-bisphosphatase
ARTH_RS06025	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ARTH_RS06075	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ARTH_RS06085	COG1376	ErfK ybiS ycfS ynhG family protein
ARTH_RS06135	COG0714	Associated with various cellular activities
ARTH_RS06140	COG0084	hydrolase, TatD family'
ARTH_RS06145	COG3583	domain protein
ARTH_RS06150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ARTH_RS06155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ARTH_RS06160	COG0488	(ABC) transporter
ARTH_RS06165	COG1309	transcriptional regulator
ARTH_RS06175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ARTH_RS06185	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ARTH_RS06190	COG0193	aminoacyl-tRNA hydrolase activity
ARTH_RS06220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ARTH_RS06225	COG1361	Conserved repeat domain
ARTH_RS06240	COG3979	chitinase
ARTH_RS06255	COG1215	transferase activity, transferring glycosyl groups
ARTH_RS06290	COG1216	Glycosyl transferase, family 2
ARTH_RS06305	COG0702	epimerase
ARTH_RS06325	COG1988	membrane-bound metal-dependent
ARTH_RS06335	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ARTH_RS06340	COG0446	pyridine nucleotide-disulphide oxidoreductase
ARTH_RS06385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ARTH_RS06385	COG1648	precorrin-2 dehydrogenase activity
ARTH_RS06390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ARTH_RS06400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARTH_RS06405	COG1959	2 iron, 2 sulfur cluster binding
ARTH_RS06430	COG0243	molybdopterin cofactor binding
ARTH_RS06435	COG2223	nitrite transmembrane transporter activity
ARTH_RS06440	COG0477	Major facilitator Superfamily
ARTH_RS06450	COG4770	biotin carboxylase activity
ARTH_RS06455	COG0424	maF-like protein
ARTH_RS06465	COG2409	Drug exporters of the RND superfamily
ARTH_RS06480	COG1823	symporter activity
ARTH_RS06495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ARTH_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS06505	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ARTH_RS06505	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ARTH_RS06530	COG0714	Associated with various cellular activities
ARTH_RS06550	COG0631	protein serine/threonine phosphatase activity
ARTH_RS06570	COG1674	ftsk spoiiie
ARTH_RS06580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ARTH_RS06585	COG0483	inositol monophosphate 1-phosphatase activity
ARTH_RS06590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARTH_RS06600	COG0251	oxidation-reduction process
ARTH_RS06605	COG4565	transcriptional regulatory protein
ARTH_RS06610	COG3290	protein histidine kinase activity
ARTH_RS06615	COG2851	Citrate transporter
ARTH_RS06620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ARTH_RS06625	COG0154	amidase activity
ARTH_RS06630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ARTH_RS06635	COG0583	DNA-binding transcription factor activity
ARTH_RS06640	COG1063	alcohol dehydrogenase
ARTH_RS06655	COG1228	amidohydrolase
ARTH_RS06660	COG0588	phosphoglycerate mutase activity
ARTH_RS06675	COG2873	o-acetylhomoserine
ARTH_RS06680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ARTH_RS06690	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ARTH_RS06725	COG0400	carboxylic ester hydrolase activity
ARTH_RS06740	COG0423	glycine-tRNA ligase activity
ARTH_RS06750	COG0204	Acyl-transferase
ARTH_RS06780	COG0358	DNA primase activity
ARTH_RS06805	COG2814	Major facilitator Superfamily
ARTH_RS06815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ARTH_RS06945	COG0052	Belongs to the universal ribosomal protein uS2 family
ARTH_RS06950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ARTH_RS06955	COG0528	UMP kinase activity
ARTH_RS06960	COG0233	cytoplasmic translational termination
ARTH_RS06975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ARTH_RS06990	COG3275	phosphorelay sensor kinase activity
ARTH_RS07000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ARTH_RS07020	COG0022	dehydrogenase e1 component
ARTH_RS07025	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARTH_RS07035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ARTH_RS07045	COG1960	acyl-CoA dehydrogenase activity
ARTH_RS07070	COG0589	response to stress
ARTH_RS07090	COG3290	protein histidine kinase activity
ARTH_RS07105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ARTH_RS07110	COG0750	zinc metalloprotease
ARTH_RS07130	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ARTH_RS07145	COG0442	prolyl-tRNA aminoacylation
ARTH_RS07175	COG0779	Required for maturation of 30S ribosomal subunits
ARTH_RS07190	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ARTH_RS07195	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ARTH_RS07205	COG0590	tRNA wobble adenosine to inosine editing
ARTH_RS07210	COG3118	belongs to the thioredoxin family
ARTH_RS07230	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ARTH_RS07265	COG3483	tryptophan 2,3-dioxygenase activity
ARTH_RS07275	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ARTH_RS07280	COG1185	polyribonucleotide nucleotidyltransferase activity
ARTH_RS07285	COG0612	Peptidase, M16
ARTH_RS07315	COG0745	RESPONSE REGULATOR receiver
ARTH_RS07320	COG5002	protein histidine kinase activity
ARTH_RS07340	COG0521	Mo-molybdopterin cofactor biosynthetic process
ARTH_RS07350	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ARTH_RS07370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARTH_RS07375	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ARTH_RS07380	COG1674	ftsk spoiiie
ARTH_RS07390	COG1058	Belongs to the CinA family
ARTH_RS07390	COG1546	Belongs to the CinA family
ARTH_RS07395	COG1396	sequence-specific DNA binding
ARTH_RS07410	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ARTH_RS07415	COG2137	regulation of response to DNA damage stimulus
ARTH_RS07420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ARTH_RS07425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ARTH_RS07430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ARTH_RS07435	COG2813	Specifically methylates the guanine in position
ARTH_RS07440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ARTH_RS07450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ARTH_RS07460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ARTH_RS07465	COG0131	Imidazoleglycerol-phosphate dehydratase
ARTH_RS07470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ARTH_RS07475	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ARTH_RS07495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ARTH_RS07500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ARTH_RS07505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ARTH_RS07510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ARTH_RS07515	COG2261	transglycosylase associated protein
ARTH_RS07525	COG2814	Major facilitator Superfamily
ARTH_RS07540	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ARTH_RS07555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ARTH_RS07560	COG0072	phenylalanine-tRNA ligase activity
ARTH_RS07560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ARTH_RS07590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ARTH_RS07595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ARTH_RS07600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ARTH_RS07605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ARTH_RS07610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ARTH_RS07615	COG1438	arginine binding
ARTH_RS07620	COG0137	argininosuccinate synthase activity
ARTH_RS07625	COG0165	Argininosuccinate lyase
ARTH_RS07630	COG0259	pyridoxamine-phosphate oxidase activity
ARTH_RS07640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ARTH_RS07640	COG2169	Transcriptional regulator
ARTH_RS07650	COG2094	Belongs to the DNA glycosylase MPG family
ARTH_RS07655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ARTH_RS07660	COG3415	Transposase
ARTH_RS07660	COG2801	Transposase and inactivated derivatives
ARTH_RS07670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ARTH_RS07695	COG0647	UMP catabolic process
ARTH_RS07710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ARTH_RS07715	COG0497	DNA recombination
ARTH_RS07720	COG0504	CTP synthase activity
ARTH_RS07725	COG0494	nUDIX hydrolase
ARTH_RS07745	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ARTH_RS07750	COG2079	MmgE PrpD family protein
ARTH_RS07770	COG3290	protein histidine kinase activity
ARTH_RS07785	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ARTH_RS07790	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ARTH_RS07805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ARTH_RS07815	COG1160	GTP binding
ARTH_RS07825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ARTH_RS07830	COG0509	glycine decarboxylation via glycine cleavage system
ARTH_RS07835	COG1716	ATPase activity
ARTH_RS07855	COG1192	Involved in chromosome partitioning
ARTH_RS07860	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ARTH_RS07870	COG1940	carbohydrate kinase activity
ARTH_RS07895	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ARTH_RS07900	COG0515	serine threonine protein kinase
ARTH_RS07900	COG2815	serine threonine protein kinase
ARTH_RS07905	COG1388	LysM domain
ARTH_RS07905	COG3942	CHAP domain
ARTH_RS07915	COG0142	geranyltranstransferase activity
ARTH_RS07925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ARTH_RS07935	COG2001	Belongs to the MraZ family
ARTH_RS07940	COG0275	rRNA processing
ARTH_RS07950	COG0768	penicillin binding
ARTH_RS07965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ARTH_RS07970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ARTH_RS07975	COG0772	Belongs to the SEDS family
ARTH_RS07980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ARTH_RS07985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ARTH_RS07995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ARTH_RS08010	COG1799	cell septum assembly
ARTH_RS08020	COG3599	regulation of cell shape
ARTH_RS08025	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ARTH_RS08055	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ARTH_RS08060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ARTH_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS08080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ARTH_RS08085	COG0174	glutamine synthetase
ARTH_RS08090	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ARTH_RS08100	COG0765	amino acid transport
ARTH_RS08105	COG1126	abc transporter atp-binding protein
ARTH_RS08145	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ARTH_RS08150	COG0321	lipoyl(octanoyl) transferase activity
ARTH_RS08165	COG4946	Tricorn protease homolog
ARTH_RS08165	COG0793	Belongs to the peptidase S41A family
ARTH_RS08170	COG1764	response to oxidative stress
ARTH_RS08180	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARTH_RS08185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ARTH_RS08190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ARTH_RS08210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ARTH_RS08235	COG1271	oxidase subunit
ARTH_RS08240	COG1294	oxidase, subunit
ARTH_RS08245	COG4988	ABC transporter
ARTH_RS08260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ARTH_RS08265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ARTH_RS08265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ARTH_RS08280	COG1435	thymidine kinase activity
ARTH_RS08305	COG0756	dUTP diphosphatase activity
ARTH_RS08330	COG0569	domain protein
ARTH_RS08335	COG0531	amino acid
ARTH_RS08340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ARTH_RS08345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ARTH_RS08350	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ARTH_RS08370	COG0667	Aldo Keto reductase
ARTH_RS08395	COG1024	Enoyl-CoA hydratase
ARTH_RS08395	COG1250	3-hydroxyacyl-CoA dehydrogenase
ARTH_RS08400	COG0183	Belongs to the thiolase family
ARTH_RS08405	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ARTH_RS08430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ARTH_RS08505	COG0242	peptide deformylase activity
ARTH_RS08510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ARTH_RS08520	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ARTH_RS08535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARTH_RS08535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARTH_RS08540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARTH_RS08540	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARTH_RS08545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ARTH_RS08550	COG0140	phosphoribosyl-ATP diphosphatase activity
ARTH_RS08555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ARTH_RS08560	COG0107	imidazoleglycerol-phosphate synthase activity
ARTH_RS08570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ARTH_RS08590	COG0134	indole-3-glycerol-phosphate synthase activity
ARTH_RS08595	COG0133	tryptophan synthase activity
ARTH_RS08600	COG0159	tryptophan synthase activity
ARTH_RS08605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ARTH_RS08610	COG0067	glutamate synthase
ARTH_RS08610	COG0069	glutamate synthase activity
ARTH_RS08610	COG0070	glutamate synthase
ARTH_RS08645	COG5492	domain, Protein
ARTH_RS08650	COG1609	Transcriptional regulator
ARTH_RS08655	COG3119	arylsulfatase activity
ARTH_RS08660	COG3119	arylsulfatase activity
ARTH_RS08690	COG0395	ABC-type sugar transport system, permease component
ARTH_RS08695	COG3119	arylsulfatase activity
ARTH_RS08700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ARTH_RS08705	COG1940	carbohydrate kinase activity
ARTH_RS08720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ARTH_RS08730	COG3119	arylsulfatase activity
ARTH_RS08755	COG1234	tRNA 3'-trailer cleavage
ARTH_RS08760	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS08780	COG2124	cytochrome p450
ARTH_RS08820	COG0531	amino acid
ARTH_RS08835	COG5416	Lipopolysaccharide assembly protein A domain
ARTH_RS08850	COG0589	response to stress
ARTH_RS08870	COG0686	Belongs to the AlaDH PNT family
ARTH_RS08875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARTH_RS08880	COG0765	amino acid transport
ARTH_RS08885	COG0765	amino acid transport
ARTH_RS08890	COG1126	abc transporter atp-binding protein
ARTH_RS08900	COG3473	Maleate cis-trans isomerase
ARTH_RS08915	COG0477	Major facilitator Superfamily
ARTH_RS08930	COG0247	lactate metabolic process
ARTH_RS08930	COG0277	FAD linked oxidase domain protein
ARTH_RS08935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ARTH_RS08940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARTH_RS08945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARTH_RS08950	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ARTH_RS08960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARTH_RS08965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ARTH_RS08970	COG0006	proline dipeptidase activity
ARTH_RS09015	COG0745	RESPONSE REGULATOR receiver
ARTH_RS09020	COG5002	protein histidine kinase activity
ARTH_RS09025	COG0745	RESPONSE REGULATOR receiver
ARTH_RS09030	COG0789	Transcriptional regulator
ARTH_RS09070	COG3572	ergothioneine biosynthetic process
ARTH_RS09080	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS09085	COG0477	Major facilitator Superfamily
ARTH_RS09090	COG1063	alcohol dehydrogenase
ARTH_RS09100	COG1105	Belongs to the carbohydrate kinase PfkB family
ARTH_RS09105	COG3958	Transketolase
ARTH_RS09110	COG3959	Transketolase, thiamine diphosphate binding domain
ARTH_RS09115	COG1063	alcohol dehydrogenase
ARTH_RS09120	COG1414	Transcriptional regulator
ARTH_RS09130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARTH_RS09135	COG1737	Transcriptional regulator
ARTH_RS09140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARTH_RS09145	COG2140	Oxalate decarboxylase
ARTH_RS09155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ARTH_RS09160	COG1063	alcohol dehydrogenase
ARTH_RS09165	COG1063	alcohol dehydrogenase
ARTH_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS09175	COG0800	Aldolase
ARTH_RS09185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ARTH_RS09195	COG1129	ABC transporter
ARTH_RS09200	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARTH_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS09215	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ARTH_RS09220	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ARTH_RS09225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARTH_RS09230	COG2814	Major facilitator Superfamily
ARTH_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS09250	COG1063	alcohol dehydrogenase
ARTH_RS09260	COG1063	alcohol dehydrogenase
ARTH_RS09265	COG1879	ABC-type sugar transport system periplasmic component
ARTH_RS09270	COG1129	ABC transporter
ARTH_RS09275	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARTH_RS09285	COG3387	PFAM Glycoside hydrolase 15-related
ARTH_RS09300	COG0693	protein deglycase activity
ARTH_RS09305	COG0583	DNA-binding transcription factor activity
ARTH_RS09320	COG1609	Transcriptional regulator
ARTH_RS09335	COG3250	beta-galactosidase activity
ARTH_RS09340	COG1472	Belongs to the glycosyl hydrolase 3 family
ARTH_RS09345	COG3250	beta-galactosidase activity
ARTH_RS09395	COG4702	Belongs to the UPF0303 family
ARTH_RS09405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ARTH_RS09405	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ARTH_RS09410	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ARTH_RS09415	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS09420	COG1024	Enoyl-CoA hydratase
ARTH_RS09430	COG4670	ketone body catabolic process
ARTH_RS09450	COG1175	transmembrane transport
ARTH_RS09455	COG0395	ABC-type sugar transport system, permease component
ARTH_RS09465	COG0800	Aldolase
ARTH_RS09470	COG0464	growth
ARTH_RS09485	COG2354	Protein conserved in bacteria
ARTH_RS09500	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ARTH_RS09505	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ARTH_RS09510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ARTH_RS09565	COG3711	transcriptional antiterminator
ARTH_RS09570	COG2723	6-phospho-beta-galactosidase activity
ARTH_RS09575	COG1263	PTS System
ARTH_RS09575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ARTH_RS09575	COG2190	(PTS) system
ARTH_RS09580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ARTH_RS09590	COG2814	Major facilitator Superfamily
ARTH_RS09610	COG2186	Transcriptional regulator
ARTH_RS09620	COG4948	Mandelate Racemase Muconate Lactonizing
ARTH_RS09675	COG1082	Xylose isomerase domain protein TIM barrel
ARTH_RS09685	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARTH_RS09690	COG1129	ABC transporter
ARTH_RS09705	COG1609	Transcriptional regulator
ARTH_RS09710	COG4213	ABC transporter substrate-binding protein
ARTH_RS09720	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARTH_RS09740	COG1609	Transcriptional regulator
ARTH_RS09770	COG0583	DNA-binding transcription factor activity
ARTH_RS09780	COG4829	muconolactone delta-isomerase
ARTH_RS09785	COG3485	protocatechuate 3,4-dioxygenase
ARTH_RS09790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ARTH_RS09800	COG1454	alcohol dehydrogenase
ARTH_RS09805	COG0501	Belongs to the peptidase M48B family
ARTH_RS09820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARTH_RS09840	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS09845	COG0395	ABC-type sugar transport system, permease component
ARTH_RS09850	COG1175	transmembrane transport
ARTH_RS09860	COG3684	Belongs to the aldolase LacD family
ARTH_RS09870	COG0673	inositol 2-dehydrogenase activity
ARTH_RS09905	COG2226	methyltransferase
ARTH_RS09915	COG0477	Major facilitator Superfamily
ARTH_RS09945	COG1396	sequence-specific DNA binding
ARTH_RS09950	COG0492	ferredoxin-NADP+ reductase activity
ARTH_RS09955	COG2226	methyltransferase
ARTH_RS10005	COG2124	cytochrome p450
ARTH_RS10010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ARTH_RS10015	COG0673	inositol 2-dehydrogenase activity
ARTH_RS10020	COG1126	abc transporter atp-binding protein
ARTH_RS10025	COG0765	amino acid transport
ARTH_RS10045	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ARTH_RS10070	COG0454	-acetyltransferase
ARTH_RS10075	COG0563	adenylate kinase activity
ARTH_RS10080	COG1414	Transcriptional regulator
ARTH_RS10090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ARTH_RS10090	COG0574	Belongs to the PEP-utilizing enzyme family
ARTH_RS10125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ARTH_RS10125	COG2755	lipolytic protein G-D-S-L family
ARTH_RS10140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ARTH_RS10155	COG0405	Gamma-glutamyltransferase
ARTH_RS10165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARTH_RS10180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ARTH_RS10190	COG2186	Transcriptional regulator
ARTH_RS10200	COG0702	epimerase
ARTH_RS10210	COG2828	Protein conserved in bacteria
ARTH_RS10245	COG1643	Atp-dependent helicase
ARTH_RS10275	COG0009	L-threonylcarbamoyladenylate synthase
ARTH_RS10295	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ARTH_RS10305	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ARTH_RS10305	COG3608	succinylglutamate desuccinylase aspartoacylase
ARTH_RS10340	COG2197	response regulator
ARTH_RS10345	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ARTH_RS10360	COG0589	response to stress
ARTH_RS10370	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARTH_RS10385	COG2814	Major facilitator Superfamily
ARTH_RS10390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARTH_RS10425	COG2050	protein possibly involved in aromatic compounds catabolism
ARTH_RS10435	COG4552	Acetyltransferase involved in intracellular survival and related
ARTH_RS10440	COG0539	negative regulation of cytoplasmic translation
ARTH_RS10455	COG1739	Uncharacterized protein family UPF0029
ARTH_RS10460	COG0237	dephospho-CoA kinase activity
ARTH_RS10460	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ARTH_RS10465	COG0556	nucleotide-excision repair
ARTH_RS10490	COG4106	trans-aconitate 2-methyltransferase activity
ARTH_RS10505	COG2188	Transcriptional regulator
ARTH_RS10515	COG0546	phosphoglycolate phosphatase activity
ARTH_RS10525	COG0322	excinuclease ABC activity
ARTH_RS10530	COG1660	Displays ATPase and GTPase activities
ARTH_RS10535	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ARTH_RS10540	COG1481	regulation of sporulation
ARTH_RS10545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ARTH_RS10550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ARTH_RS10555	COG0126	phosphoglycerate kinase activity
ARTH_RS10560	COG0149	triose-phosphate isomerase activity
ARTH_RS10565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ARTH_RS10575	COG0363	glucosamine-6-phosphate deaminase activity
ARTH_RS10590	COG0166	Belongs to the GPI family
ARTH_RS10595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ARTH_RS10605	COG0109	protoheme IX farnesyltransferase activity
ARTH_RS10610	COG1612	heme a metabolic process
ARTH_RS10620	COG1131	(ABC) transporter
ARTH_RS10645	COG0396	ATPase activity
ARTH_RS10650	COG2151	metal-sulfur cluster biosynthetic enzyme
ARTH_RS10660	COG0318	PFAM AMP-dependent synthetase and ligase
ARTH_RS10675	COG1122	ATPase activity
ARTH_RS10680	COG1268	BioY protein
ARTH_RS10685	COG0488	(ABC) transporter
ARTH_RS10710	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS10725	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS10730	COG3830	Belongs to the UPF0237 family
ARTH_RS10730	COG0560	Phosphoserine phosphatase
ARTH_RS10735	COG1119	ATPase activity
ARTH_RS10750	COG0254	rRNA binding
ARTH_RS10765	COG2855	membrane
ARTH_RS10815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ARTH_RS10820	COG0297	glycogen (starch) synthase activity
ARTH_RS10835	COG0183	Belongs to the thiolase family
ARTH_RS10840	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS10860	COG0435	Glutathione S-transferase
ARTH_RS10895	COG0579	oxidoreductase
ARTH_RS10900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ARTH_RS10940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARTH_RS10960	COG0656	L-ascorbic acid biosynthetic process
ARTH_RS10965	COG1968	undecaprenyl-diphosphatase activity
ARTH_RS10970	COG0215	cysteine-tRNA ligase activity
ARTH_RS10980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARTH_RS10995	COG1222	aaa ATPase
ARTH_RS11000	COG4122	O-methyltransferase activity
ARTH_RS11010	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ARTH_RS11015	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ARTH_RS11020	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ARTH_RS11025	COG0545	Peptidyl-prolyl cis-trans isomerase
ARTH_RS11045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ARTH_RS11050	COG0805	protein transport
ARTH_RS11055	COG4581	dead DEAH box helicase
ARTH_RS11060	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ARTH_RS11065	COG1216	Glycosyl transferase, family 2
ARTH_RS11090	COG1506	peptidase
ARTH_RS11090	COG0823	Involved in the tonB-independent uptake of proteins
ARTH_RS11090	COG4946	Tricorn protease homolog
ARTH_RS11095	COG0242	peptide deformylase activity
ARTH_RS11110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARTH_RS11125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ARTH_RS11130	COG4974	Belongs to the 'phage' integrase family
ARTH_RS11170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ARTH_RS11175	COG1845	cytochrome c oxidase, subunit III
ARTH_RS11180	COG2010	Cytochrome c
ARTH_RS11185	COG0723	plastoquinol--plastocyanin reductase activity
ARTH_RS11190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ARTH_RS11200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ARTH_RS11210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ARTH_RS11215	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ARTH_RS11235	COG0167	dihydroorotate dehydrogenase activity
ARTH_RS11250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ARTH_RS11255	COG1381	Involved in DNA repair and RecF pathway recombination
ARTH_RS11260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ARTH_RS11265	COG3590	peptidase
ARTH_RS11270	COG1316	TRANSCRIPTIONal
ARTH_RS11275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ARTH_RS11285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ARTH_RS11300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ARTH_RS11305	COG0484	heat shock protein binding
ARTH_RS11310	COG1420	regulation of RNA biosynthetic process
ARTH_RS11325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ARTH_RS11330	COG0481	GTPase activity
ARTH_RS11340	COG0268	Binds directly to 16S ribosomal RNA
ARTH_RS11355	COG2183	response to ionizing radiation
ARTH_RS11365	COG1307	EDD domain protein, DegV family
ARTH_RS11370	COG0495	leucyl-tRNA aminoacylation
ARTH_RS11375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ARTH_RS11380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ARTH_RS11385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ARTH_RS11395	COG0656	L-ascorbic acid biosynthetic process
ARTH_RS11405	COG0438	transferase activity, transferring glycosyl groups
ARTH_RS11415	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ARTH_RS11425	COG1758	RNA polymerase activity
ARTH_RS11430	COG0194	GDP metabolic process
ARTH_RS11435	COG0194	GDP metabolic process
ARTH_RS11440	COG0284	orotidine-5'-phosphate decarboxylase activity
ARTH_RS11445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ARTH_RS11450	COG0505	Belongs to the CarA family
ARTH_RS11460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ARTH_RS11465	COG0540	Belongs to the ATCase OTCase family
ARTH_RS11470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ARTH_RS11480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ARTH_RS11485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ARTH_RS11495	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ARTH_RS11505	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ARTH_RS11510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ARTH_RS11525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ARTH_RS11540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ARTH_RS11560	COG1414	Transcriptional regulator
ARTH_RS11570	COG1053	succinate dehydrogenase
ARTH_RS11580	COG0477	Major facilitator Superfamily
ARTH_RS11590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ARTH_RS11600	COG0124	histidyl-tRNA synthetase
ARTH_RS11610	COG1196	nuclear chromosome segregation
ARTH_RS11620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ARTH_RS11625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ARTH_RS11630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ARTH_RS11640	COG2255	four-way junction helicase activity
ARTH_RS11645	COG0632	four-way junction helicase activity
ARTH_RS11650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ARTH_RS11655	COG0217	transcriptional regulatory protein
ARTH_RS11660	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ARTH_RS11665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ARTH_RS11680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ARTH_RS11705	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ARTH_RS11710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ARTH_RS11720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ARTH_RS11725	COG0587	DNA-directed DNA polymerase activity
ARTH_RS11750	COG2135	peptidase activity
ARTH_RS11815	COG3103	Sh3 type 3 domain protein
ARTH_RS11815	COG1388	LysM domain
ARTH_RS11815	COG0791	NLP P60 protein
ARTH_RS11840	COG1234	tRNA 3'-trailer cleavage
ARTH_RS11855	COG1126	abc transporter atp-binding protein
ARTH_RS11860	COG0765	amino acid transport
ARTH_RS11865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARTH_RS11910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ARTH_RS11915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ARTH_RS11920	COG1780	Probably involved in ribonucleotide reductase function
ARTH_RS11930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ARTH_RS11935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ARTH_RS11955	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS11965	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ARTH_RS12005	COG0714	Associated with various cellular activities
ARTH_RS12025	COG1653	transport
ARTH_RS12035	COG2813	Specifically methylates the guanine in position
ARTH_RS12040	COG0492	ferredoxin-NADP+ reductase activity
ARTH_RS12045	COG2824	Alkylphosphonate utilization operon protein PhnA
ARTH_RS12070	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ARTH_RS12080	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ARTH_RS12085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ARTH_RS12090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ARTH_RS12095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ARTH_RS12100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ARTH_RS12105	COG0351	phosphomethylpyrimidine kinase
ARTH_RS12105	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ARTH_RS12105	COG0352	thiamine-phosphate diphosphorylase activity
ARTH_RS12110	COG1530	ribonuclease E activity
ARTH_RS12120	COG0105	UTP biosynthetic process
ARTH_RS12130	COG0285	dihydrofolate synthase activity
ARTH_RS12135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ARTH_RS12150	COG0525	valine-tRNA ligase activity
ARTH_RS12155	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ARTH_RS12160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ARTH_RS12165	COG0740	serine-type endopeptidase activity
ARTH_RS12170	COG0740	serine-type endopeptidase activity
ARTH_RS12175	COG0544	peptidyl-prolyl cis-trans isomerase activity
ARTH_RS12220	COG0668	transmembrane transport
ARTH_RS12240	COG1946	Acyl-CoA thioesterase
ARTH_RS12255	COG0629	single-stranded DNA binding
ARTH_RS12285	COG0673	inositol 2-dehydrogenase activity
ARTH_RS12290	COG1609	Transcriptional regulator
ARTH_RS12295	COG0657	acetylesterase activity
ARTH_RS12295	COG2755	lipolytic protein G-D-S-L family
ARTH_RS12305	COG1940	carbohydrate kinase activity
ARTH_RS12310	COG2115	Belongs to the xylose isomerase family
ARTH_RS12315	COG1070	Carbohydrate kinase
ARTH_RS12320	COG2017	converts alpha-aldose to the beta-anomer
ARTH_RS12345	COG0242	peptide deformylase activity
ARTH_RS12380	COG3022	response to hydroperoxide
ARTH_RS12390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ARTH_RS12395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ARTH_RS12405	COG1045	serine acetyltransferase
ARTH_RS12410	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS12415	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ARTH_RS12425	COG1063	alcohol dehydrogenase
ARTH_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS12435	COG2084	Dehydrogenase
ARTH_RS12440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARTH_RS12455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ARTH_RS12460	COG0477	Major facilitator Superfamily
ARTH_RS12495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ARTH_RS12510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ARTH_RS12515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ARTH_RS12520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ARTH_RS12530	COG4974	Belongs to the 'phage' integrase family
ARTH_RS12545	COG0792	nuclease activity
ARTH_RS12555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ARTH_RS12565	COG0681	Belongs to the peptidase S26 family
ARTH_RS12570	COG0335	large ribosomal subunit rRNA binding
ARTH_RS12575	COG0336	Belongs to the RNA methyltransferase TrmD family
ARTH_RS12580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ARTH_RS12585	COG1837	Belongs to the UPF0109 family
ARTH_RS12590	COG0228	four-way junction DNA binding
ARTH_RS12600	COG2514	catechol 2,3-dioxygenase activity
ARTH_RS12625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ARTH_RS12640	COG0477	Major facilitator Superfamily
ARTH_RS12675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ARTH_RS12680	COG0571	ribonuclease III activity
ARTH_RS12685	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ARTH_RS12700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ARTH_RS12720	COG0742	ribosomal rna small subunit methyltransferase
ARTH_RS12745	COG1181	Belongs to the D-alanine--D-alanine ligase family
ARTH_RS12750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ARTH_RS12760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ARTH_RS12765	COG0066	3-isopropylmalate dehydratase activity
ARTH_RS12770	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ARTH_RS12775	COG1414	Transcriptional regulator
ARTH_RS12815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ARTH_RS12820	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARTH_RS12830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ARTH_RS12835	COG0473	3-isopropylmalate dehydrogenase activity
ARTH_RS12855	COG1136	(ABC) transporter
ARTH_RS12855	COG0577	efflux transmembrane transporter activity
ARTH_RS12865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARTH_RS12870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ARTH_RS12875	COG0440	acetolactate synthase activity
ARTH_RS12885	COG0129	dihydroxy-acid dehydratase activity
ARTH_RS12890	COG0583	DNA-binding transcription factor activity
ARTH_RS12900	COG0088	Forms part of the polypeptide exit tunnel
ARTH_RS12940	COG0747	negative chemotaxis
ARTH_RS12945	COG0579	oxidoreductase
ARTH_RS12950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ARTH_RS12955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARTH_RS12965	COG1305	Transglutaminase-like
ARTH_RS12980	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARTH_RS12990	COG1104	cysteine desulfurase activity
ARTH_RS13000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ARTH_RS13005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ARTH_RS13020	COG1113	amino acid transport
ARTH_RS13030	COG0022	dehydrogenase e1 component
ARTH_RS13035	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARTH_RS13045	COG0477	Major facilitator Superfamily
ARTH_RS13070	COG0419	ATPase involved in DNA repair
ARTH_RS13075	COG0420	3'-5' exonuclease activity
ARTH_RS13080	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ARTH_RS13100	COG0586	Pfam SNARE associated Golgi protein
ARTH_RS13105	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ARTH_RS13110	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ARTH_RS13115	COG1234	tRNA 3'-trailer cleavage
ARTH_RS13120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ARTH_RS13130	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ARTH_RS13140	COG1335	isochorismatase
ARTH_RS13155	COG0363	glucosamine-6-phosphate deaminase activity
ARTH_RS13170	COG1902	pentaerythritol trinitrate reductase activity
ARTH_RS13185	COG0628	permease
ARTH_RS13200	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ARTH_RS13210	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ARTH_RS13225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ARTH_RS13230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ARTH_RS13235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ARTH_RS13240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ARTH_RS13245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ARTH_RS13250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ARTH_RS13255	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ARTH_RS13260	COG0356	it plays a direct role in the translocation of protons across the membrane
ARTH_RS13275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ARTH_RS13290	COG0009	L-threonylcarbamoyladenylate synthase
ARTH_RS13295	COG2890	protein-(glutamine-N5) methyltransferase activity
ARTH_RS13300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ARTH_RS13310	COG0083	homoserine kinase activity
ARTH_RS13315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ARTH_RS13320	COG0460	homoserine dehydrogenase
ARTH_RS13325	COG0019	diaminopimelate decarboxylase activity
ARTH_RS13330	COG0018	arginyl-trna synthetase
ARTH_RS13370	COG1643	Atp-dependent helicase
ARTH_RS13375	COG0537	adenosine 5'-monophosphoramidase activity
ARTH_RS13380	COG1064	alcohol dehydrogenase
ARTH_RS13390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ARTH_RS13410	COG1121	(ABC) transporter
ARTH_RS13425	COG1253	flavin adenine dinucleotide binding
ARTH_RS13435	COG0567	Dehydrogenase, E1 component
ARTH_RS13435	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARTH_RS13465	COG1595	DNA-templated transcription, initiation
ARTH_RS13475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ARTH_RS13485	COG0483	inositol monophosphate 1-phosphatase activity
ARTH_RS13490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ARTH_RS13505	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARTH_RS13510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARTH_RS13520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ARTH_RS13535	COG2884	Cell division ATP-binding protein ftsE
ARTH_RS13540	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ARTH_RS13605	COG1088	dTDP-glucose 4,6-dehydratase activity
ARTH_RS13650	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ARTH_RS13675	COG1216	Glycosyl transferase, family 2
ARTH_RS13705	COG2902	Dehydrogenase
ARTH_RS13740	COG0653	protein targeting
ARTH_RS13745	COG3214	Protein conserved in bacteria
ARTH_RS13750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ARTH_RS13760	COG5401	PFAM Sporulation and spore germination
ARTH_RS13765	COG5002	protein histidine kinase activity
ARTH_RS13790	COG0714	Associated with various cellular activities
ARTH_RS13815	COG4172	Belongs to the ABC transporter superfamily
ARTH_RS13825	COG0601	transmembrane transport
ARTH_RS13845	COG0482	sulfurtransferase activity
ARTH_RS13860	COG0697	spore germination
ARTH_RS13880	COG1597	lipid kinase activity
ARTH_RS13885	COG0484	heat shock protein binding
ARTH_RS13890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ARTH_RS13895	COG1595	DNA-templated transcription, initiation
ARTH_RS13915	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ARTH_RS13920	COG2086	electron transfer activity
ARTH_RS13925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ARTH_RS13935	COG1842	Phage shock protein A
ARTH_RS13945	COG0415	Belongs to the DNA photolyase family
ARTH_RS13965	COG1615	UPF0182 protein
ARTH_RS13970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ARTH_RS13990	COG2816	NAD+ diphosphatase activity
ARTH_RS14020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ARTH_RS14025	COG2011	ABC-type metal ion transport system permease component
ARTH_RS14035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ARTH_RS14045	COG0113	porphobilinogen synthase activity
ARTH_RS14055	COG0181	hydroxymethylbilane synthase activity
ARTH_RS14060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ARTH_RS14065	COG3253	May function as heme-dependent peroxidase
ARTH_RS14085	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ARTH_RS14090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ARTH_RS14115	COG2154	pterin-4-alpha-carbinolamine dehydratase
ARTH_RS14120	COG2022	thiamine diphosphate biosynthetic process
ARTH_RS14130	COG2022	thiamine diphosphate biosynthetic process
ARTH_RS14130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ARTH_RS14135	COG0352	thiamine-phosphate diphosphorylase activity
ARTH_RS14145	COG0557	exoribonuclease II activity
ARTH_RS14150	COG0513	Belongs to the DEAD box helicase family
ARTH_RS14155	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ARTH_RS14165	COG0006	proline dipeptidase activity
ARTH_RS14175	COG2239	Acts as a magnesium transporter
ARTH_RS14190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ARTH_RS14200	COG1595	DNA-templated transcription, initiation
ARTH_RS14225	COG1126	abc transporter atp-binding protein
ARTH_RS14230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARTH_RS14235	COG0765	amino acid transport
ARTH_RS14240	COG0765	amino acid transport
ARTH_RS14245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARTH_RS14250	COG2171	N-acyltransferase activity
ARTH_RS14265	COG3226	Transcriptional regulator
ARTH_RS14270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ARTH_RS14305	COG1217	gtp-binding protein TYPA
ARTH_RS14315	COG4172	Belongs to the ABC transporter superfamily
ARTH_RS14320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ARTH_RS14325	COG0601	transmembrane transport
ARTH_RS14330	COG4166	transmembrane transport
ARTH_RS14335	COG4172	Belongs to the ABC transporter superfamily
ARTH_RS14350	COG0601	transmembrane transport
ARTH_RS14355	COG4166	transmembrane transport
ARTH_RS14375	COG0012	GTP binding
ARTH_RS14385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ARTH_RS14395	COG1570	exodeoxyribonuclease VII activity
ARTH_RS14400	COG1722	exodeoxyribonuclease VII activity
ARTH_RS14405	COG2326	polyphosphate kinase activity
ARTH_RS14420	COG1174	glycine betaine transport
ARTH_RS14425	COG1174	glycine betaine transport
ARTH_RS14435	COG1162	GTPase activity
ARTH_RS14445	COG2971	BadF BadG BcrA BcrD
ARTH_RS14455	COG0583	DNA-binding transcription factor activity
ARTH_RS14460	COG2814	Major facilitator Superfamily
ARTH_RS14465	COG0626	cystathionine gamma-synthase activity
ARTH_RS14495	COG0598	Magnesium transport protein CorA
ARTH_RS14505	COG3848	Pyruvate phosphate dikinase
ARTH_RS14505	COG0574	Belongs to the PEP-utilizing enzyme family
ARTH_RS14520	COG0488	(ABC) transporter
ARTH_RS14530	COG1090	epimerase
ARTH_RS14545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ARTH_RS14550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ARTH_RS14570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ARTH_RS14570	COG0519	Catalyzes the synthesis of GMP from XMP
ARTH_RS14590	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ARTH_RS14595	COG0516	GMP reductase activity
ARTH_RS14600	COG1404	Belongs to the peptidase S8 family
ARTH_RS14605	COG1132	(ABC) transporter
ARTH_RS14625	COG2755	lipolytic protein G-D-S-L family
ARTH_RS14625	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ARTH_RS14640	COG2072	flavoprotein involved in K transport
ARTH_RS14655	COG0459	protein refolding
ARTH_RS14660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ARTH_RS14675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ARTH_RS14680	COG1472	Belongs to the glycosyl hydrolase 3 family
ARTH_RS14690	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARTH_RS14695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ARTH_RS14710	COG0802	atpase or kinase
ARTH_RS14715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ARTH_RS14720	COG1105	Belongs to the carbohydrate kinase PfkB family
ARTH_RS14735	COG0438	transferase activity, transferring glycosyl groups
ARTH_RS14740	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ARTH_RS14765	COG0667	Aldo Keto reductase
ARTH_RS14790	COG0736	holo-[acyl-carrier-protein] synthase activity
ARTH_RS14795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ARTH_RS14800	COG1072	(Pantothenic acid kinase))
ARTH_RS14810	COG1970	mechanosensitive ion channel activity
ARTH_RS14815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARTH_RS14820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ARTH_RS14825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ARTH_RS14830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ARTH_RS14855	COG0455	bacterial-type flagellum organization
ARTH_RS14895	COG2894	cell division
ARTH_RS14920	COG0745	RESPONSE REGULATOR receiver
ARTH_RS14925	COG0101	tRNA pseudouridine synthase activity
ARTH_RS14930	COG0203	ribosomal protein L17
ARTH_RS14935	COG0202	RNA polymerase activity
ARTH_RS14940	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ARTH_RS14945	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ARTH_RS14950	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ARTH_RS14955	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ARTH_RS14960	COG3191	aminopeptidase activity
ARTH_RS14975	COG1653	transport
ARTH_RS14990	COG0318	PFAM AMP-dependent synthetase and ligase
ARTH_RS14995	COG2124	cytochrome p450
ARTH_RS15000	COG1216	Glycosyl transferase, family 2
ARTH_RS15000	COG1442	glycosyl transferase family 8
ARTH_RS15005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ARTH_RS15010	COG0563	adenylate kinase activity
ARTH_RS15020	COG0200	Binds to the 23S rRNA
ARTH_RS15025	COG1841	ribosomal large subunit assembly
ARTH_RS15030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ARTH_RS15040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ARTH_RS15045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ARTH_RS15050	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ARTH_RS15055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ARTH_RS15060	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ARTH_RS15065	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ARTH_RS15070	COG0255	Belongs to the universal ribosomal protein uL29 family
ARTH_RS15075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ARTH_RS15080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ARTH_RS15085	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ARTH_RS15090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ARTH_RS15095	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ARTH_RS15100	COG0089	rRNA binding
ARTH_RS15105	COG0088	Forms part of the polypeptide exit tunnel
ARTH_RS15110	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ARTH_RS15115	COG0051	transcription antitermination factor activity, RNA binding
ARTH_RS15130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ARTH_RS15135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ARTH_RS15140	COG0049	tRNA binding
ARTH_RS15145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ARTH_RS15150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ARTH_RS15155	COG0085	RNA polymerase activity
ARTH_RS15165	COG0183	Belongs to the thiolase family
ARTH_RS15170	COG0442	prolyl-tRNA aminoacylation
ARTH_RS15175	COG0737	Belongs to the 5'-nucleotidase family
ARTH_RS15180	COG0222	ribosome binding
ARTH_RS15185	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ARTH_RS15200	COG0081	regulation of translation
ARTH_RS15205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ARTH_RS15225	COG0436	Aminotransferase
ARTH_RS15230	COG2197	response regulator
ARTH_RS15280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ARTH_RS15290	COG3485	protocatechuate 3,4-dioxygenase
ARTH_RS15300	COG0745	RESPONSE REGULATOR receiver
ARTH_RS15305	COG0456	acetyltransferase
ARTH_RS15310	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ARTH_RS15330	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ARTH_RS15345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ARTH_RS15360	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ARTH_RS15365	COG0738	Major facilitator superfamily
ARTH_RS15375	COG2030	dehydratase
ARTH_RS15385	COG0659	secondary active sulfate transmembrane transporter activity
ARTH_RS15415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARTH_RS15425	COG4989	oxidoreductase activity
ARTH_RS15430	COG0366	Alpha amylase catalytic
ARTH_RS15435	COG0395	ABC-type sugar transport system, permease component
ARTH_RS15440	COG1175	transmembrane transport
ARTH_RS15450	COG1940	carbohydrate kinase activity
ARTH_RS15460	COG0702	epimerase
ARTH_RS15470	COG1595	DNA-templated transcription, initiation
ARTH_RS15475	COG0706	membrane insertase activity
ARTH_RS15515	COG0754	glutathionylspermidine amidase activity
ARTH_RS15525	COG1960	acyl-CoA dehydrogenase activity
ARTH_RS15535	COG5650	phosphatidylinositol metabolic process
ARTH_RS15550	COG1051	belongs to the nudix hydrolase family
ARTH_RS15565	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ARTH_RS15580	COG0318	PFAM AMP-dependent synthetase and ligase
ARTH_RS15590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ARTH_RS15600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ARTH_RS15620	COG1666	GTP binding
ARTH_RS15625	COG0501	Belongs to the peptidase M48B family
ARTH_RS15655	COG1116	anion transmembrane transporter activity
ARTH_RS15660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARTH_RS15665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARTH_RS15670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ARTH_RS15680	COG0531	amino acid
ARTH_RS15730	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS15735	COG3835	regulator
ARTH_RS15745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ARTH_RS15745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ARTH_RS15775	COG2186	Transcriptional regulator
ARTH_RS15835	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ARTH_RS15850	COG1690	Belongs to the RtcB family
ARTH_RS15875	COG0175	sulfate reduction
ARTH_RS15880	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ARTH_RS15890	COG2860	membrane
ARTH_RS15905	COG0142	geranyltranstransferase activity
ARTH_RS15915	COG2226	methyltransferase
ARTH_RS15920	COG1169	isochorismate synthase
ARTH_RS15925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARTH_RS15930	COG0765	amino acid transport
ARTH_RS15945	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ARTH_RS15950	COG1609	Transcriptional regulator
ARTH_RS15955	COG1621	beta-fructofuranosidase activity
ARTH_RS15960	COG0395	ABC-type sugar transport system, permease component
ARTH_RS15965	COG1175	transmembrane transport
ARTH_RS15975	COG1609	Transcriptional regulator
ARTH_RS15985	COG1175	transmembrane transport
ARTH_RS15990	COG0395	ABC-type sugar transport system, permease component
ARTH_RS16005	COG0018	arginyl-trna synthetase
ARTH_RS16015	COG4948	Mandelate Racemase Muconate Lactonizing
ARTH_RS16035	COG0436	Aminotransferase
ARTH_RS16055	COG2072	flavoprotein involved in K transport
ARTH_RS16200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ARTH_RS16200	COG2755	lipolytic protein G-D-S-L family
ARTH_RS16210	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARTH_RS16215	COG0022	dehydrogenase e1 component
ARTH_RS16230	COG0489	protein tyrosine kinase activity
ARTH_RS16265	COG0438	transferase activity, transferring glycosyl groups
ARTH_RS16275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ARTH_RS16295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ARTH_RS16305	COG1024	Enoyl-CoA hydratase
ARTH_RS16310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ARTH_RS16315	COG2151	metal-sulfur cluster biosynthetic enzyme
ARTH_RS16320	COG3396	Phenylacetate-CoA oxygenase
ARTH_RS16325	COG3460	Phenylacetate-CoA oxygenase
ARTH_RS16330	COG3396	Phenylacetate-CoA oxygenase
ARTH_RS16345	COG0489	protein tyrosine kinase activity
ARTH_RS16375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARTH_RS16380	COG1316	TRANSCRIPTIONal
ARTH_RS16430	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ARTH_RS16440	COG0280	phosphate acetyltransferase
ARTH_RS16440	COG0857	belongs to the CobB CobQ family
ARTH_RS16450	COG2814	Major facilitator Superfamily
ARTH_RS16470	COG2050	protein possibly involved in aromatic compounds catabolism
ARTH_RS16505	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS16505	COG2030	dehydratase
ARTH_RS16510	COG2050	protein possibly involved in aromatic compounds catabolism
ARTH_RS16520	COG1528	Iron-storage protein
ARTH_RS16525	COG1595	DNA-templated transcription, initiation
ARTH_RS16560	COG1250	3-hydroxyacyl-CoA dehydrogenase
ARTH_RS16565	COG1024	Enoyl-CoA hydratase
ARTH_RS16570	COG0183	Belongs to the thiolase family
ARTH_RS16600	COG2146	nitrite reductase [NAD(P)H] activity
ARTH_RS16605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ARTH_RS16615	COG0488	(ABC) transporter
ARTH_RS16620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ARTH_RS16625	COG1121	(ABC) transporter
ARTH_RS16635	COG1266	CAAX protease self-immunity
ARTH_RS16645	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ARTH_RS16675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ARTH_RS16685	COG0785	Cytochrome C biogenesis protein
ARTH_RS16695	COG0406	alpha-ribazole phosphatase activity
ARTH_RS16700	COG2353	YceI-like domain
ARTH_RS16715	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ARTH_RS16735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ARTH_RS16740	COG3458	cephalosporin-C deacetylase activity
ARTH_RS16745	COG1070	Carbohydrate kinase
ARTH_RS16750	COG3347	Dehydrogenase
ARTH_RS16750	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS16760	COG3254	rhamnose metabolic process
ARTH_RS16765	COG1609	Transcriptional regulator
ARTH_RS16780	COG0667	Aldo Keto reductase
ARTH_RS16790	COG2755	lipolytic protein G-D-S-L family
ARTH_RS16795	COG0395	ABC-type sugar transport system, permease component
ARTH_RS16800	COG4209	transmembrane transport
ARTH_RS16805	COG1653	transport
ARTH_RS16810	COG5578	integral membrane protein
ARTH_RS16825	COG2814	Major facilitator Superfamily
ARTH_RS16835	COG0395	ABC-type sugar transport system, permease component
ARTH_RS16840	COG1175	transmembrane transport
ARTH_RS16860	COG0395	ABC-type sugar transport system, permease component
ARTH_RS16865	COG1175	transmembrane transport
ARTH_RS16890	COG0659	secondary active sulfate transmembrane transporter activity
ARTH_RS16905	COG4948	Mandelate Racemase Muconate Lactonizing
ARTH_RS16910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARTH_RS16920	COG0673	inositol 2-dehydrogenase activity
ARTH_RS16925	COG1609	Transcriptional regulator
ARTH_RS16950	COG0640	Transcriptional regulator
ARTH_RS16960	COG0123	including yeast histone deacetylase and acetoin utilization protein
ARTH_RS16965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ARTH_RS16970	COG0569	domain protein
ARTH_RS16975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ARTH_RS16980	COG4941	Belongs to the sigma-70 factor family
ARTH_RS16990	COG1082	Xylose isomerase domain protein TIM barrel
ARTH_RS16995	COG0248	Ppx GppA phosphatase
ARTH_RS17010	COG1754	DNA topoisomerase type I activity
ARTH_RS17010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ARTH_RS17020	COG2890	protein-(glutamine-N5) methyltransferase activity
ARTH_RS17025	COG1432	Conserved Protein
ARTH_RS17055	COG1054	Belongs to the UPF0176 family
ARTH_RS17065	COG1205	dead DEAH box helicase
ARTH_RS17065	COG1111	helicase
ARTH_RS17115	COG0494	nUDIX hydrolase
ARTH_RS17120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ARTH_RS17130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARTH_RS17145	COG0395	ABC-type sugar transport system, permease component
ARTH_RS17150	COG1349	DNA-binding transcription factor activity
ARTH_RS17155	COG1609	Transcriptional regulator
ARTH_RS17170	COG0395	ABC-type sugar transport system, permease component
ARTH_RS17200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ARTH_RS17230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ARTH_RS17235	COG1408	metallophosphoesterase
ARTH_RS17245	COG1132	(ABC) transporter
ARTH_RS17265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ARTH_RS17270	COG0151	Belongs to the GarS family
ARTH_RS17290	COG1301	dicarboxylic acid transport
ARTH_RS17305	COG1953	Uracil, thiamine, allantoin
ARTH_RS17310	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ARTH_RS17335	COG0667	Aldo Keto reductase
ARTH_RS17340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ARTH_RS17350	COG3608	succinylglutamate desuccinylase aspartoacylase
ARTH_RS17350	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ARTH_RS17355	COG2252	PERMEase
ARTH_RS17360	COG0590	tRNA wobble adenosine to inosine editing
ARTH_RS17370	COG1793	dna ligase
ARTH_RS17370	COG3285	dna ligase
ARTH_RS17385	COG2233	PERMEase
ARTH_RS17395	COG1953	Uracil, thiamine, allantoin
ARTH_RS17400	COG1414	Transcriptional regulator
ARTH_RS17410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ARTH_RS17420	COG3257	ureidoglycine aminohydrolase activity
ARTH_RS17440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARTH_RS17450	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARTH_RS17455	COG3387	PFAM Glycoside hydrolase 15-related
ARTH_RS17480	COG0484	heat shock protein binding
ARTH_RS17500	COG4335	DNA alkylation repair
ARTH_RS17515	COG0667	Aldo Keto reductase
ARTH_RS17520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ARTH_RS17535	COG0589	response to stress
ARTH_RS17555	COG0438	transferase activity, transferring glycosyl groups
ARTH_RS17570	COG1609	Transcriptional regulator
ARTH_RS17575	COG2182	Extracellular solute-binding protein
ARTH_RS17585	COG0395	ABC-type sugar transport system, permease component
ARTH_RS17595	COG0673	inositol 2-dehydrogenase activity
ARTH_RS17605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ARTH_RS17610	COG4152	abc transporter atp-binding protein
ARTH_RS17645	COG1404	Belongs to the peptidase S8 family
ARTH_RS17650	COG1053	succinate dehydrogenase
ARTH_RS17660	COG0446	pyridine nucleotide-disulphide oxidoreductase
ARTH_RS17660	COG1902	pentaerythritol trinitrate reductase activity
ARTH_RS17670	COG0477	Major facilitator Superfamily
ARTH_RS17690	COG0693	protein deglycase activity
ARTH_RS17700	COG2197	response regulator
ARTH_RS17705	COG4585	Histidine kinase
ARTH_RS17725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ARTH_RS17730	COG1414	Transcriptional regulator
ARTH_RS17735	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ARTH_RS17740	COG0477	Major facilitator Superfamily
ARTH_RS17760	COG3226	Transcriptional regulator
ARTH_RS17765	COG4977	sequence-specific DNA binding
ARTH_RS17770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ARTH_RS17800	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS17805	COG0363	glucosamine-6-phosphate deaminase activity
ARTH_RS17810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ARTH_RS17815	COG1263	PTS System
ARTH_RS17820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ARTH_RS17825	COG2190	(PTS) system
ARTH_RS17825	COG1263	PTS System
ARTH_RS17825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ARTH_RS17830	COG2188	Transcriptional regulator
ARTH_RS17850	COG1802	Transcriptional regulator
ARTH_RS17865	COG3971	2-oxopent-4-enoate hydratase activity
ARTH_RS17875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ARTH_RS17885	COG3265	gluconokinase activity
ARTH_RS17890	COG2610	gluconate transmembrane transporter activity
ARTH_RS17950	COG0477	Major facilitator Superfamily
ARTH_RS17965	COG2186	Transcriptional regulator
ARTH_RS17970	COG1027	Aspartate ammonia-lyase
ARTH_RS17975	COG1301	dicarboxylic acid transport
ARTH_RS17985	COG2508	Transcriptional regulator
ARTH_RS17990	COG2066	Belongs to the glutaminase family
ARTH_RS18000	COG0028	Belongs to the TPP enzyme family
ARTH_RS18050	COG0833	amino acid
ARTH_RS18055	COG0460	homoserine dehydrogenase
ARTH_RS18060	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS18090	COG3739	integral membrane protein
ARTH_RS18140	COG4336	lyase activity
ARTH_RS18170	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ARTH_RS18175	COG0318	PFAM AMP-dependent synthetase and ligase
ARTH_RS18210	COG1737	Transcriptional regulator
ARTH_RS18220	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS18245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ARTH_RS18250	COG1228	amidohydrolase
ARTH_RS18260	COG0402	S-adenosylhomocysteine deaminase activity
ARTH_RS18270	COG2084	Dehydrogenase
ARTH_RS18275	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ARTH_RS18275	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ARTH_RS18280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ARTH_RS18285	COG0673	inositol 2-dehydrogenase activity
ARTH_RS18290	COG1609	Transcriptional regulator
ARTH_RS18375	COG3845	ABC transporter
ARTH_RS18380	COG0596	Alpha beta hydrolase
ARTH_RS18385	COG3268	Saccharopine dehydrogenase
ARTH_RS18390	COG0646	methionine synthase
ARTH_RS18390	COG1410	methionine synthase
ARTH_RS18425	COG0833	amino acid
ARTH_RS18465	COG1129	ABC transporter
ARTH_RS18470	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARTH_RS18495	COG1228	amidohydrolase
ARTH_RS18540	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ARTH_RS18545	COG3383	formate dehydrogenase (NAD+) activity
ARTH_RS18585	COG3665	Urea carboxylase-associated protein
ARTH_RS18620	COG1301	dicarboxylic acid transport
ARTH_RS18640	COG3401	FG-GAP repeat protein
ARTH_RS18655	COG0673	inositol 2-dehydrogenase activity
ARTH_RS18665	COG0673	inositol 2-dehydrogenase activity
ARTH_RS18680	COG1653	transport
ARTH_RS18685	COG1609	Transcriptional regulator
ARTH_RS18690	COG3622	Belongs to the hyi family
ARTH_RS18695	COG2084	Dehydrogenase
ARTH_RS18700	COG3960	tartronate-semialdehyde synthase activity
ARTH_RS18705	COG1929	Belongs to the glycerate kinase type-1 family
ARTH_RS18710	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ARTH_RS18715	COG0745	RESPONSE REGULATOR receiver
ARTH_RS18745	COG1760	l-serine dehydratase
ARTH_RS18770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARTH_RS18775	COG1802	Transcriptional regulator
ARTH_RS18810	COG0583	DNA-binding transcription factor activity
ARTH_RS18820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ARTH_RS18820	COG1017	nitric oxide dioxygenase activity
ARTH_RS18825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ARTH_RS18855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARTH_RS18870	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS18875	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ARTH_RS18880	COG0477	Major facilitator Superfamily
ARTH_RS18900	COG2205	protein histidine kinase activity
ARTH_RS18925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ARTH_RS18955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ARTH_RS18965	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS18970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ARTH_RS18990	COG3585	molybdate ion transport
ARTH_RS19015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ARTH_RS19020	COG0598	Magnesium transport protein CorA
ARTH_RS19035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARTH_RS19040	COG0135	phosphoribosylanthranilate isomerase activity
ARTH_RS19090	COG5001	Diguanylate cyclase
ARTH_RS19090	COG3300	MHYT domain
ARTH_RS19095	COG0667	Aldo Keto reductase
ARTH_RS19110	COG1113	amino acid transport
ARTH_RS19125	COG1473	amidohydrolase
ARTH_RS19130	COG0477	Major facilitator Superfamily
ARTH_RS19140	COG0477	Major facilitator Superfamily
ARTH_RS19150	COG2807	transmembrane transport
ARTH_RS19160	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ARTH_RS19185	COG0436	Aminotransferase
ARTH_RS19220	COG2202	Pas domain
ARTH_RS19220	COG2205	protein histidine kinase activity
ARTH_RS19230	COG1621	beta-fructofuranosidase activity
ARTH_RS19240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ARTH_RS19270	COG2267	carboxylic ester hydrolase activity
ARTH_RS19275	COG0789	Transcriptional regulator
ARTH_RS19280	COG0484	heat shock protein binding
ARTH_RS19285	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ARTH_RS19290	COG0443	Heat shock 70 kDa protein
ARTH_RS19310	COG2409	Drug exporters of the RND superfamily
ARTH_RS19325	COG2226	methyltransferase
ARTH_RS19335	COG1280	lysine exporter protein (LysE YggA)
ARTH_RS19340	COG0542	response to heat
ARTH_RS19350	COG0477	Major facilitator Superfamily
ARTH_RS19360	COG1960	acyl-CoA dehydrogenase activity
ARTH_RS19370	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS19385	COG0640	Transcriptional regulator
ARTH_RS19395	COG2814	Major facilitator Superfamily
ARTH_RS19410	COG1937	Protein conserved in bacteria
ARTH_RS19415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARTH_RS19430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARTH_RS19435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ARTH_RS19445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARTH_RS19470	COG0731	radical SAM domain protein
ARTH_RS19485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARTH_RS19495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ARTH_RS19510	COG2318	DinB family
ARTH_RS19520	COG2200	EAL domain
ARTH_RS19520	COG2199	diguanylate cyclase activity
ARTH_RS19530	COG2986	histidine ammonia-lyase
ARTH_RS19560	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARTH_RS19565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ARTH_RS19575	COG1122	ATPase activity
ARTH_RS19580	COG4721	ABC-type cobalt transport system, permease component
ARTH_RS19590	COG1320	monovalent cation:proton antiporter activity
ARTH_RS19595	COG2212	antiporter activity
ARTH_RS19600	COG1863	multisubunit Na H antiporter MnhE subunit
ARTH_RS19605	COG0651	ATP synthesis coupled electron transport
ARTH_RS19610	COG1006	Multisubunit Na H antiporter MnhC subunit
ARTH_RS19615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ARTH_RS19615	COG2111	Na H antiporter
ARTH_RS19630	COG0475	glutathione-regulated potassium exporter activity
ARTH_RS19635	COG0717	Belongs to the dCTP deaminase family
ARTH_RS19665	COG0583	DNA-binding transcription factor activity
ARTH_RS19675	COG1012	belongs to the aldehyde dehydrogenase family
ARTH_RS19680	COG0531	amino acid
ARTH_RS19690	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ARTH_RS19700	COG3387	PFAM Glycoside hydrolase 15-related
ARTH_RS19705	COG0745	RESPONSE REGULATOR receiver
ARTH_RS19715	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ARTH_RS19725	COG1175	transmembrane transport
ARTH_RS19735	COG1609	Transcriptional regulator
ARTH_RS19740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARTH_RS19775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARTH_RS19780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARTH_RS19790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARTH_RS19800	COG1126	abc transporter atp-binding protein
ARTH_RS19805	COG0765	amino acid transport
ARTH_RS19820	COG0433	COG0433 Predicted ATPase
ARTH_RS19835	COG3336	cytochrome c oxidase
ARTH_RS19840	COG0776	regulation of translation
ARTH_RS19870	COG1609	Transcriptional regulator
ARTH_RS19890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ARTH_RS19895	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ARTH_RS19900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ARTH_RS19905	COG1017	nitric oxide dioxygenase activity
ARTH_RS19905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ARTH_RS19925	COG2066	Belongs to the glutaminase family
ARTH_RS19925	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ARTH_RS19955	COG1120	ATPase activity
ARTH_RS19960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ARTH_RS19965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ARTH_RS19980	COG1309	transcriptional regulator
ARTH_RS20025	COG3012	SEC-C Motif Domain Protein
ARTH_RS20035	COG0667	Aldo Keto reductase
ARTH_RS20040	COG0667	Aldo Keto reductase
ARTH_RS20045	COG0702	epimerase
ARTH_RS20055	COG0698	ribose 5-phosphate isomerase
ARTH_RS20060	COG2376	Dihydroxyacetone kinase
ARTH_RS20065	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS20070	COG1082	Xylose isomerase domain protein TIM barrel
ARTH_RS20080	COG3959	Transketolase, thiamine diphosphate binding domain
ARTH_RS20085	COG3958	Transketolase
ARTH_RS20095	COG1028	Short-chain dehydrogenase reductase Sdr
ARTH_RS20145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ARTH_RS20160	COG3550	peptidyl-serine autophosphorylation
ARTH_RS20170	COG2186	Transcriptional regulator
ARTH_RS20180	COG1027	Aspartate ammonia-lyase
ARTH_RS20190	COG0039	L-malate dehydrogenase activity
ARTH_RS20225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ARTH_RS20250	COG1280	lysine exporter protein (LysE YggA)
ARTH_RS20275	COG1309	transcriptional regulator
ARTH_RS20280	COG2814	Major facilitator Superfamily
ARTH_RS20285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ARTH_RS20290	COG0477	Major facilitator Superfamily
ARTH_RS20295	COG0477	Major facilitator Superfamily
ARTH_RS20300	COG2814	Major facilitator Superfamily
ARTH_RS20305	COG1846	Transcriptional regulator
ARTH_RS20315	COG0246	Mannitol dehydrogenase
ARTH_RS20320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ARTH_RS20320	COG2213	PTS system mannitol-specific
ARTH_RS20330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ARTH_RS20350	COG0277	FAD linked oxidase domain protein
ARTH_RS20360	COG0686	Belongs to the AlaDH PNT family
ARTH_RS20365	COG0673	inositol 2-dehydrogenase activity
ARTH_RS20395	COG0431	NADPH-dependent FMN reductase
ARTH_RS20405	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ARTH_RS20410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ARTH_RS20415	COG0589	response to stress
ARTH_RS20420	COG0318	PFAM AMP-dependent synthetase and ligase
ARTH_RS20430	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARTH_RS20435	COG0022	dehydrogenase e1 component
ARTH_RS20445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ARTH_RS20450	COG1950	PFAM Membrane protein of
ARTH_RS20465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ARTH_RS20470	COG0406	alpha-ribazole phosphatase activity
ARTH_RS20495	COG1607	acyl-coa hydrolase
ARTH_RS20500	COG1840	ABC-type Fe3 transport system, periplasmic component
ARTH_RS20510	COG1178	ABC-type Fe3 transport system permease component
ARTH_RS20530	COG2814	Major facilitator Superfamily
ARTH_RS20535	COG0243	molybdopterin cofactor binding
ARTH_RS20550	COG1970	mechanosensitive ion channel activity
ARTH_RS20555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ARTH_RS20590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ARTH_RS20600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ARTH_RS20605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ARTH_RS20615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ARTH_RS20625	COG2271	Major facilitator Superfamily
ARTH_RS20630	COG1802	Transcriptional regulator
ARTH_RS20650	COG1597	lipid kinase activity
ARTH_RS20660	COG1414	Transcriptional regulator
ARTH_RS20665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ARTH_RS20675	COG0183	Belongs to the thiolase family
ARTH_RS20680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ARTH_RS20695	COG3485	protocatechuate 3,4-dioxygenase
ARTH_RS20700	COG3485	protocatechuate 3,4-dioxygenase
ARTH_RS20705	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ARTH_RS20705	COG1082	Xylose isomerase domain protein TIM barrel
ARTH_RS20710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ARTH_RS20715	COG1414	Transcriptional regulator
ARTH_RS20725	COG1793	dna ligase
ARTH_RS20790	COG2814	Major facilitator Superfamily
ARTH_RS20795	COG1937	Protein conserved in bacteria
ARTH_RS20820	COG0697	spore germination
ARTH_RS20845	COG2259	Doxx family
ARTH_RS20855	COG1607	acyl-coa hydrolase
ARTH_RS20860	COG0305	Participates in initiation and elongation during chromosome replication
ARTH_RS20890	COG0359	binds to the 23S rRNA
ARTH_RS20895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ARTH_RS20905	COG0360	Binds together with S18 to 16S ribosomal RNA
ARTH_RS20915	COG0438	transferase activity, transferring glycosyl groups
ARTH_RS20945	COG1362	aminopeptidase activity
ARTH_RS20970	COG1113	amino acid transport
ARTH_RS20975	COG2197	response regulator
ARTH_RS20980	COG4585	Histidine kinase
ARTH_RS20990	COG1131	(ABC) transporter
ARTH_RS21000	COG0738	Major facilitator superfamily
ARTH_RS21015	COG1620	l-lactate permease
ARTH_RS21025	COG0488	(ABC) transporter
ARTH_RS21030	COG3693	PFAM glycoside hydrolase, family 10
ARTH_RS21040	COG2197	response regulator
ARTH_RS21045	COG3851	Histidine kinase
ARTH_RS21055	COG1136	(ABC) transporter
ARTH_RS21060	COG1733	regulation of RNA biosynthetic process
ARTH_RS21085	COG0406	alpha-ribazole phosphatase activity
ARTH_RS21090	COG0617	tRNA 3'-terminal CCA addition
ARTH_RS21110	COG0492	ferredoxin-NADP+ reductase activity
ARTH_RS21115	COG3118	belongs to the thioredoxin family
ARTH_RS21125	COG1192	Involved in chromosome partitioning
ARTH_RS21130	COG0357	Ribosomal RNA small subunit methyltransferase G
ARTH_RS21140	COG0706	membrane insertase activity
ARTH_RS21145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ARTH_RS21150	COG0594	ribonuclease P activity
ARTH_RS21580	COG0477	Major facilitator Superfamily
ARTH_RS21645	COG1984	allophanate hydrolase subunit 2
ARTH_RS21650	COG4770	biotin carboxylase activity
ARTH_RS21800	COG2233	PERMEase
ARTH_RS21940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARTH_RS21960	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ARTH_RS21990	COG0187	DNA topoisomerase II activity
ARTH_RS22210	COG0395	ABC-type sugar transport system, permease component
ARTH_RS22370	COG0673	inositol 2-dehydrogenase activity
ARTH_RS23025	COG0519	Catalyzes the synthesis of GMP from XMP
ARTH_RS23030	COG0739	heme binding
ARTH_RS23030	COG0741	lytic transglycosylase activity
ARTH_RS23030	COG1196	nuclear chromosome segregation
ARTH_RS23055	COG0515	serine threonine protein kinase
ARTH_RS23095	COG3300	MHYT domain
ARTH_RS23095	COG5001	Diguanylate cyclase
ARTH_RS23110	COG1053	succinate dehydrogenase
ARTH_RS23140	COG3287	FIST C domain
ARTH_RS23140	COG2200	EAL domain
ARTH_RS23140	COG2199	diguanylate cyclase activity
ARTH_RS23155	COG5416	Lipopolysaccharide assembly protein A domain
ARTH_RS23210	COG1404	Belongs to the peptidase S8 family
ARTH_RS23215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ARTH_RS23215	COG2755	lipolytic protein G-D-S-L family