locus-tag	class	description
LFT47_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LFT47_RS00010	COG0592	DNA-directed DNA polymerase activity
LFT47_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LFT47_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LFT47_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LFT47_RS00030	COG0187	DNA topoisomerase II activity
LFT47_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LFT47_RS00040	COG3266	domain, Protein
LFT47_RS00065	COG1215	transferase activity, transferring glycosyl groups
LFT47_RS00105	COG0640	Transcriptional regulator
LFT47_RS00110	COG2818	Glycosylase
LFT47_RS00120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LFT47_RS00130	COG3764	Sortase (surface protein transpeptidase)
LFT47_RS00140	COG0515	serine threonine protein kinase
LFT47_RS00140	COG2815	serine threonine protein kinase
LFT47_RS00145	COG0515	serine threonine protein kinase
LFT47_RS00150	COG0768	penicillin binding
LFT47_RS00165	COG1716	ATPase activity
LFT47_RS00190	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_RS00195	COG1984	allophanate hydrolase subunit 2
LFT47_RS00200	COG4770	biotin carboxylase activity
LFT47_RS00235	COG1609	Transcriptional regulator
LFT47_RS00240	COG0659	secondary active sulfate transmembrane transporter activity
LFT47_RS00270	COG0561	phosphatase activity
LFT47_RS00300	COG4941	Belongs to the sigma-70 factor family
LFT47_RS00310	COG1929	Belongs to the glycerate kinase type-1 family
LFT47_RS00320	COG2233	PERMEase
LFT47_RS00325	COG0778	Nitroreductase
LFT47_RS00345	COG3104	oligopeptide transport
LFT47_RS00350	COG0154	amidase activity
LFT47_RS00355	COG3340	Belongs to the peptidase S51 family
LFT47_RS00360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LFT47_RS00360	COG0425	Belongs to the sulfur carrier protein TusA family
LFT47_RS00375	COG1597	lipid kinase activity
LFT47_RS00380	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LFT47_RS00390	COG0561	phosphatase activity
LFT47_RS00410	COG2027	D-alanyl-D-alanine carboxypeptidase
LFT47_RS00420	COG0037	tRNA processing
LFT47_RS00455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LFT47_RS00460	COG0302	gtp cyclohydrolase
LFT47_RS00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LFT47_RS00500	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LFT47_RS00505	COG2814	Major facilitator Superfamily
LFT47_RS00525	COG1802	Transcriptional regulator
LFT47_RS00530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LFT47_RS00535	COG1960	acyl-CoA dehydrogenase activity
LFT47_RS00565	COG0596	Alpha beta hydrolase
LFT47_RS00570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LFT47_RS00590	COG1506	peptidase
LFT47_RS00590	COG0823	Involved in the tonB-independent uptake of proteins
LFT47_RS00595	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LFT47_RS00600	COG2376	Dihydroxyacetone kinase
LFT47_RS00605	COG1461	Dihydroxyacetone kinase
LFT47_RS00620	COG2226	methyltransferase
LFT47_RS00635	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LFT47_RS00640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LFT47_RS00680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LFT47_RS00685	COG0306	phosphate transporter
LFT47_RS00705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LFT47_RS00710	COG0586	Pfam SNARE associated Golgi protein
LFT47_RS00715	COG0831	urea catabolic process
LFT47_RS00720	COG0832	Belongs to the urease beta subunit family
LFT47_RS00725	COG0804	urea catabolic process
LFT47_RS00730	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LFT47_RS00735	COG0830	nickel cation binding
LFT47_RS00740	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LFT47_RS00745	COG0829	nickel cation binding
LFT47_RS00750	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LFT47_RS00755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LFT47_RS00755	COG1796	DNA polymerase
LFT47_RS00770	COG0656	L-ascorbic acid biosynthetic process
LFT47_RS00780	COG0667	Aldo Keto reductase
LFT47_RS00785	COG0656	L-ascorbic acid biosynthetic process
LFT47_RS00805	COG3360	Dodecin
LFT47_RS00810	COG2271	Major facilitator Superfamily
LFT47_RS00815	COG0251	oxidation-reduction process
LFT47_RS00835	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS00840	COG0583	DNA-binding transcription factor activity
LFT47_RS00845	COG2186	Transcriptional regulator
LFT47_RS00860	COG2084	Dehydrogenase
LFT47_RS00865	COG2610	gluconate transmembrane transporter activity
LFT47_RS00945	COG0300	oxidoreductase activity
LFT47_RS00970	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_RS00980	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS00985	COG3962	Belongs to the TPP enzyme family
LFT47_RS00995	COG0673	inositol 2-dehydrogenase activity
LFT47_RS01010	COG0673	inositol 2-dehydrogenase activity
LFT47_RS01050	COG0542	response to heat
LFT47_RS01055	COG0346	lactoylglutathione lyase activity
LFT47_RS01060	COG5002	protein histidine kinase activity
LFT47_RS01065	COG0745	RESPONSE REGULATOR receiver
LFT47_RS01075	COG0477	Major facilitator Superfamily
LFT47_RS01080	COG2890	protein-(glutamine-N5) methyltransferase activity
LFT47_RS01100	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LFT47_RS01115	COG3237	CsbD-like
LFT47_RS01140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LFT47_RS01145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LFT47_RS01145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LFT47_RS01145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT47_RS01155	COG1349	DNA-binding transcription factor activity
LFT47_RS01190	COG1129	ABC transporter
LFT47_RS01195	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_RS01220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT47_RS01235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LFT47_RS01270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_RS01275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_RS01280	COG1984	allophanate hydrolase subunit 2
LFT47_RS01285	COG2733	membrane
LFT47_RS01325	COG4122	O-methyltransferase activity
LFT47_RS01350	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS01355	COG3706	GGDEF domain
LFT47_RS01370	COG1175	transmembrane transport
LFT47_RS01375	COG0395	ABC-type sugar transport system, permease component
LFT47_RS01380	COG1609	Transcriptional regulator
LFT47_RS01415	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LFT47_RS01440	COG0010	Belongs to the arginase family
LFT47_RS01445	COG2252	PERMEase
LFT47_RS01465	COG0574	Belongs to the PEP-utilizing enzyme family
LFT47_RS01465	COG3848	Pyruvate phosphate dikinase
LFT47_RS01475	COG1609	Transcriptional regulator
LFT47_RS01505	COG1302	Protein conserved in bacteria
LFT47_RS01535	COG0366	Alpha amylase catalytic
LFT47_RS01560	COG1609	Transcriptional regulator
LFT47_RS01580	COG2197	response regulator
LFT47_RS01585	COG4585	Histidine kinase
LFT47_RS01595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LFT47_RS01605	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LFT47_RS01620	COG0415	Belongs to the DNA photolyase family
LFT47_RS01640	COG1024	Enoyl-CoA hydratase
LFT47_RS01650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LFT47_RS01660	COG1609	Transcriptional regulator
LFT47_RS01670	COG1175	transmembrane transport
LFT47_RS01675	COG0395	ABC-type sugar transport system, permease component
LFT47_RS01685	COG0673	inositol 2-dehydrogenase activity
LFT47_RS01700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LFT47_RS01720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LFT47_RS01720	COG0357	Ribosomal RNA small subunit methyltransferase G
LFT47_RS01725	COG0191	fructose-bisphosphate aldolase activity
LFT47_RS01745	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LFT47_RS01760	COG1832	CoA-binding protein
LFT47_RS01770	COG2315	Protein conserved in bacteria
LFT47_RS01780	COG1653	transport
LFT47_RS01785	COG1175	transmembrane transport
LFT47_RS01790	COG0395	ABC-type sugar transport system, permease component
LFT47_RS01810	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LFT47_RS01815	COG0047	phosphoribosylformylglycinamidine synthase activity
LFT47_RS01855	COG1846	Transcriptional regulator
LFT47_RS01875	COG1131	(ABC) transporter
LFT47_RS01885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LFT47_RS01900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LFT47_RS01935	COG2135	peptidase activity
LFT47_RS02015	COG0739	heme binding
LFT47_RS02290	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS02310	COG0739	heme binding
LFT47_RS02310	COG0741	lytic transglycosylase activity
LFT47_RS02310	COG1196	nuclear chromosome segregation
LFT47_RS02315	COG0386	Belongs to the glutathione peroxidase family
LFT47_RS02340	COG4166	transmembrane transport
LFT47_RS02350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_RS02355	COG0444	Belongs to the ABC transporter superfamily
LFT47_RS02360	COG4608	Belongs to the ABC transporter superfamily
LFT47_RS02395	COG1309	transcriptional regulator
LFT47_RS02410	COG0477	Major facilitator Superfamily
LFT47_RS02415	COG0823	Involved in the tonB-independent uptake of proteins
LFT47_RS02425	COG0673	inositol 2-dehydrogenase activity
LFT47_RS02430	COG0673	inositol 2-dehydrogenase activity
LFT47_RS02440	COG0395	ABC-type sugar transport system, permease component
LFT47_RS02475	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LFT47_RS02485	COG1476	TRANSCRIPTIONal
LFT47_RS02505	COG1131	(ABC) transporter
LFT47_RS02520	COG0343	queuine tRNA-ribosyltransferase activity
LFT47_RS02565	COG1960	acyl-CoA dehydrogenase activity
LFT47_RS02570	COG3254	rhamnose metabolic process
LFT47_RS02575	COG0477	Major facilitator Superfamily
LFT47_RS02580	COG1609	Transcriptional regulator
LFT47_RS02585	COG0673	inositol 2-dehydrogenase activity
LFT47_RS02610	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LFT47_RS02620	COG0586	Pfam SNARE associated Golgi protein
LFT47_RS02635	COG0564	pseudouridine synthase activity
LFT47_RS02670	COG2364	Membrane
LFT47_RS02675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT47_RS02680	COG1201	RNA secondary structure unwinding
LFT47_RS02705	COG0475	glutathione-regulated potassium exporter activity
LFT47_RS02705	COG0569	domain protein
LFT47_RS02775	COG1846	Transcriptional regulator
LFT47_RS02795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LFT47_RS02825	COG1621	beta-fructofuranosidase activity
LFT47_RS02840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LFT47_RS02880	COG1254	Belongs to the acylphosphatase family
LFT47_RS02905	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LFT47_RS02910	COG1309	transcriptional regulator
LFT47_RS02915	COG0477	Major facilitator Superfamily
LFT47_RS02930	COG1609	Transcriptional regulator
LFT47_RS02940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LFT47_RS02950	COG0363	glucosamine-6-phosphate deaminase activity
LFT47_RS02965	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LFT47_RS02970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LFT47_RS02985	COG2205	protein histidine kinase activity
LFT47_RS02990	COG0745	RESPONSE REGULATOR receiver
LFT47_RS03015	COG0697	spore germination
LFT47_RS03025	COG1309	transcriptional regulator
LFT47_RS03030	COG1511	domain protein
LFT47_RS03045	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LFT47_RS03050	COG1940	carbohydrate kinase activity
LFT47_RS03060	COG4608	Belongs to the ABC transporter superfamily
LFT47_RS03065	COG0444	Belongs to the ABC transporter superfamily
LFT47_RS03075	COG0747	negative chemotaxis
LFT47_RS03080	COG2188	Transcriptional regulator
LFT47_RS03090	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LFT47_RS03095	COG0574	Belongs to the PEP-utilizing enzyme family
LFT47_RS03095	COG3848	Pyruvate phosphate dikinase
LFT47_RS03115	COG0514	ATP-dependent DNA helicase (RecQ)
LFT47_RS03120	COG2814	Major facilitator Superfamily
LFT47_RS03135	COG1505	serine-type exopeptidase activity
LFT47_RS03155	COG1968	undecaprenyl-diphosphatase activity
LFT47_RS03160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LFT47_RS03170	COG0604	alcohol dehydrogenase
LFT47_RS03195	COG0656	L-ascorbic acid biosynthetic process
LFT47_RS03200	COG1609	Transcriptional regulator
LFT47_RS03210	COG1175	transmembrane transport
LFT47_RS03215	COG0395	ABC-type sugar transport system, permease component
LFT47_RS03225	COG0673	inositol 2-dehydrogenase activity
LFT47_RS03250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LFT47_RS03315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LFT47_RS03320	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LFT47_RS03340	COG0588	phosphoglycerate mutase activity
LFT47_RS03370	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LFT47_RS03375	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LFT47_RS03380	COG0215	cysteine-tRNA ligase activity
LFT47_RS03385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LFT47_RS03410	COG0366	Alpha amylase catalytic
LFT47_RS03415	COG0366	Alpha amylase catalytic
LFT47_RS03420	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LFT47_RS03455	COG0277	FAD linked oxidase domain protein
LFT47_RS03465	COG0402	S-adenosylhomocysteine deaminase activity
LFT47_RS03470	COG4608	Belongs to the ABC transporter superfamily
LFT47_RS03475	COG0444	Belongs to the ABC transporter superfamily
LFT47_RS03480	COG0601	transmembrane transport
LFT47_RS03490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_RS03505	COG3842	ATPase activity
LFT47_RS03530	COG2508	Transcriptional regulator
LFT47_RS03575	COG0656	L-ascorbic acid biosynthetic process
LFT47_RS03585	COG1129	ABC transporter
LFT47_RS03590	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_RS03610	COG0698	ribose 5-phosphate isomerase
LFT47_RS03620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT47_RS03625	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS03625	COG3347	Dehydrogenase
LFT47_RS03640	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_RS03645	COG1129	ABC transporter
LFT47_RS03655	COG1070	Carbohydrate kinase
LFT47_RS03660	COG1349	DNA-binding transcription factor activity
LFT47_RS03685	COG1940	carbohydrate kinase activity
LFT47_RS03690	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_RS03695	COG3457	Alanine racemase
LFT47_RS03705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LFT47_RS03710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LFT47_RS03725	COG3511	phospholipase C
LFT47_RS03730	COG0671	phosphoesterase, PA-phosphatase related
LFT47_RS03750	COG0454	-acetyltransferase
LFT47_RS03760	COG5001	Diguanylate cyclase
LFT47_RS03770	COG1846	Transcriptional regulator
LFT47_RS03770	COG1940	carbohydrate kinase activity
LFT47_RS03775	COG0366	Alpha amylase catalytic
LFT47_RS03785	COG1175	transmembrane transport
LFT47_RS03790	COG0395	ABC-type sugar transport system, permease component
LFT47_RS03805	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT47_RS03815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LFT47_RS03825	COG0444	Belongs to the ABC transporter superfamily
LFT47_RS03850	COG4166	transmembrane transport
LFT47_RS03855	COG1335	isochorismatase
LFT47_RS03900	COG0402	S-adenosylhomocysteine deaminase activity
LFT47_RS03910	COG0154	amidase activity
LFT47_RS03915	COG3290	protein histidine kinase activity
LFT47_RS03920	COG4565	transcriptional regulatory protein
LFT47_RS03930	COG3832	glyoxalase III activity
LFT47_RS03935	COG0640	Transcriptional regulator
LFT47_RS03960	COG1177	transmembrane transport
LFT47_RS03965	COG3842	ATPase activity
LFT47_RS03970	COG0483	inositol monophosphate 1-phosphatase activity
LFT47_RS04005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LFT47_RS04020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LFT47_RS04040	COG1815	bacterial-type flagellum-dependent cell motility
LFT47_RS04050	COG1677	Flagellar hook-basal body complex protein FliE
LFT47_RS04055	COG1766	The M ring may be actively involved in energy transduction
LFT47_RS04060	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LFT47_RS04070	COG1157	protein secretion by the type III secretion system
LFT47_RS04090	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LFT47_RS04110	COG0604	alcohol dehydrogenase
LFT47_RS04125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LFT47_RS04130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LFT47_RS04135	COG0531	amino acid
LFT47_RS04140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LFT47_RS04150	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LFT47_RS04170	COG0671	phosphoesterase, PA-phosphatase related
LFT47_RS04185	COG5002	protein histidine kinase activity
LFT47_RS04215	COG3842	ATPase activity
LFT47_RS04235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LFT47_RS04240	COG1360	Flagellar Motor Protein
LFT47_RS04250	COG3585	molybdate ion transport
LFT47_RS04280	COG1338	Plays a role in the flagellum-specific transport system
LFT47_RS04295	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LFT47_RS04300	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LFT47_RS04310	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LFT47_RS04325	COG0477	Major facilitator Superfamily
LFT47_RS04335	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LFT47_RS04335	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LFT47_RS04340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LFT47_RS04345	COG0509	glycine decarboxylation via glycine cleavage system
LFT47_RS04350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LFT47_RS04360	COG1017	nitric oxide dioxygenase activity
LFT47_RS04360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT47_RS04410	COG0459	protein refolding
LFT47_RS04415	COG0328	RNA-DNA hybrid ribonuclease activity
LFT47_RS04425	COG2205	protein histidine kinase activity
LFT47_RS04430	COG0745	RESPONSE REGULATOR receiver
LFT47_RS04465	COG1278	Cold shock
LFT47_RS04475	COG2814	Major facilitator Superfamily
LFT47_RS04490	COG0739	heme binding
LFT47_RS04505	COG0746	molybdenum cofactor guanylyltransferase activity
LFT47_RS04525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LFT47_RS04535	COG1126	abc transporter atp-binding protein
LFT47_RS04540	COG0765	amino acid transport
LFT47_RS04545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT47_RS04560	COG0488	(ABC) transporter
LFT47_RS04565	COG1132	(ABC) transporter
LFT47_RS04630	COG0483	inositol monophosphate 1-phosphatase activity
LFT47_RS04635	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LFT47_RS04690	COG0045	succinate-CoA ligase (ADP-forming) activity
LFT47_RS04700	COG1942	4-Oxalocrotonate Tautomerase
LFT47_RS04715	COG3962	Belongs to the TPP enzyme family
LFT47_RS04730	COG0673	inositol 2-dehydrogenase activity
LFT47_RS04735	COG1082	Xylose isomerase domain protein TIM barrel
LFT47_RS04745	COG0659	secondary active sulfate transmembrane transporter activity
LFT47_RS04765	COG1609	Transcriptional regulator
LFT47_RS04775	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_RS04785	COG0673	inositol 2-dehydrogenase activity
LFT47_RS04790	COG0673	inositol 2-dehydrogenase activity
LFT47_RS04795	COG0673	inositol 2-dehydrogenase activity
LFT47_RS04805	COG0673	inositol 2-dehydrogenase activity
LFT47_RS04810	COG3718	enzyme involved in inositol metabolism
LFT47_RS04815	COG2188	Transcriptional regulator
LFT47_RS04830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LFT47_RS04850	COG0477	Major facilitator Superfamily
LFT47_RS04860	COG4176	ABC-type proline glycine betaine transport system permease component
LFT47_RS04865	COG4175	Glycine betaine
LFT47_RS04865	COG0517	IMP dehydrogenase activity
LFT47_RS04870	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS04890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LFT47_RS04905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT47_RS04925	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LFT47_RS04950	COG1760	l-serine dehydratase
LFT47_RS04970	COG0726	polysaccharide deacetylase
LFT47_RS05000	COG1396	sequence-specific DNA binding
LFT47_RS05030	COG0028	Belongs to the TPP enzyme family
LFT47_RS05040	COG0477	Major facilitator Superfamily
LFT47_RS05060	COG3142	Participates in the control of copper homeostasis
LFT47_RS05070	COG1401	restriction endodeoxyribonuclease activity
LFT47_RS05090	COG5002	protein histidine kinase activity
LFT47_RS05095	COG0745	RESPONSE REGULATOR receiver
LFT47_RS05105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LFT47_RS05125	COG1902	pentaerythritol trinitrate reductase activity
LFT47_RS05140	COG2376	Dihydroxyacetone kinase
LFT47_RS05145	COG0698	ribose 5-phosphate isomerase
LFT47_RS05150	COG1250	3-hydroxyacyl-CoA dehydrogenase
LFT47_RS05155	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS05160	COG2271	Major facilitator Superfamily
LFT47_RS05165	COG0149	triose-phosphate isomerase activity
LFT47_RS05200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LFT47_RS05225	COG0640	Transcriptional regulator
LFT47_RS05255	COG1309	transcriptional regulator
LFT47_RS05265	COG0477	Major facilitator Superfamily
LFT47_RS05285	COG0531	amino acid
LFT47_RS05295	COG1396	sequence-specific DNA binding
LFT47_RS05310	COG4565	transcriptional regulatory protein
LFT47_RS05315	COG1116	anion transmembrane transporter activity
LFT47_RS05320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LFT47_RS05335	COG0667	Aldo Keto reductase
LFT47_RS05380	COG1111	helicase
LFT47_RS05380	COG1205	dead DEAH box helicase
LFT47_RS05390	COG1002	Type II restriction enzyme, methylase subunits
LFT47_RS05395	COG1401	restriction endodeoxyribonuclease activity
LFT47_RS05570	COG1131	(ABC) transporter
LFT47_RS05600	COG1116	anion transmembrane transporter activity
LFT47_RS05630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LFT47_RS05650	COG2268	Band 7 protein
LFT47_RS05655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LFT47_RS05660	COG2814	Major facilitator Superfamily
LFT47_RS05675	COG0179	Fumarylacetoacetate (FAA) hydrolase
LFT47_RS05705	COG2271	Major facilitator Superfamily
LFT47_RS05710	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LFT47_RS05720	COG0138	bifunctional purine biosynthesis protein purh
LFT47_RS05735	COG2838	Isocitrate dehydrogenase
LFT47_RS05740	COG3639	organic phosphonate transmembrane transporter activity
LFT47_RS05755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LFT47_RS05790	COG0673	inositol 2-dehydrogenase activity
LFT47_RS05795	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LFT47_RS05800	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LFT47_RS05805	COG3639	organic phosphonate transmembrane transporter activity
LFT47_RS05810	COG1136	(ABC) transporter
LFT47_RS05815	COG0577	efflux transmembrane transporter activity
LFT47_RS05815	COG1136	(ABC) transporter
LFT47_RS05860	COG1131	(ABC) transporter
LFT47_RS05875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LFT47_RS05880	COG0531	amino acid
LFT47_RS05910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LFT47_RS05915	COG4585	Histidine kinase
LFT47_RS05920	COG2197	response regulator
LFT47_RS05930	COG1131	(ABC) transporter
LFT47_RS05955	COG0180	Tryptophanyl-tRNA synthetase
LFT47_RS05975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LFT47_RS05990	COG2009	succinate dehydrogenase
LFT47_RS06000	COG1473	amidohydrolase
LFT47_RS06000	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT47_RS06005	COG1846	Transcriptional regulator
LFT47_RS06010	COG1764	response to oxidative stress
LFT47_RS06015	COG2130	NADP-dependent
LFT47_RS06020	COG1744	ABC transporter substrate-binding protein PnrA-like
LFT47_RS06025	COG3845	ABC transporter
LFT47_RS06030	COG4603	Belongs to the binding-protein-dependent transport system permease family
LFT47_RS06035	COG1079	Belongs to the binding-protein-dependent transport system permease family
LFT47_RS06050	COG0586	Pfam SNARE associated Golgi protein
LFT47_RS06055	COG0586	Pfam SNARE associated Golgi protein
LFT47_RS06060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LFT47_RS06065	COG3956	TIGRFAM MazG family protein
LFT47_RS06070	COG0148	phosphopyruvate hydratase activity
LFT47_RS06095	COG1252	NADH dehydrogenase
LFT47_RS06125	COG0411	ABC transporter
LFT47_RS06140	COG0183	Belongs to the thiolase family
LFT47_RS06145	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LFT47_RS06155	COG2017	converts alpha-aldose to the beta-anomer
LFT47_RS06165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LFT47_RS06170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LFT47_RS06180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LFT47_RS06190	COG1331	Highly conserved protein containing a thioredoxin domain
LFT47_RS06200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LFT47_RS06205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LFT47_RS06245	COG0114	fumarate hydratase activity
LFT47_RS06250	COG0288	reversible hydration of carbon dioxide
LFT47_RS06260	COG1494	fructose-1,6-bisphosphatase
LFT47_RS06275	COG1482	cell wall glycoprotein biosynthetic process
LFT47_RS06280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LFT47_RS06330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LFT47_RS06340	COG1376	ErfK ybiS ycfS ynhG family protein
LFT47_RS06385	COG0714	Associated with various cellular activities
LFT47_RS06390	COG0084	hydrolase, TatD family'
LFT47_RS06395	COG3583	domain protein
LFT47_RS06400	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LFT47_RS06405	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LFT47_RS06410	COG0488	(ABC) transporter
LFT47_RS06415	COG1309	transcriptional regulator
LFT47_RS06425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LFT47_RS06435	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LFT47_RS06440	COG0193	aminoacyl-tRNA hydrolase activity
LFT47_RS06465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LFT47_RS06475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LFT47_RS06485	COG3979	chitinase
LFT47_RS06495	COG1215	transferase activity, transferring glycosyl groups
LFT47_RS06530	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LFT47_RS06550	COG1988	membrane-bound metal-dependent
LFT47_RS06580	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LFT47_RS06585	COG0446	pyridine nucleotide-disulphide oxidoreductase
LFT47_RS06595	COG2814	Major facilitator Superfamily
LFT47_RS06605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LFT47_RS06605	COG1648	precorrin-2 dehydrogenase activity
LFT47_RS06610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LFT47_RS06610	COG2146	nitrite reductase [NAD(P)H] activity
LFT47_RS06620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LFT47_RS06625	COG1621	beta-fructofuranosidase activity
LFT47_RS06650	COG1136	(ABC) transporter
LFT47_RS06715	COG0243	molybdopterin cofactor binding
LFT47_RS06720	COG2223	nitrite transmembrane transporter activity
LFT47_RS06725	COG0477	Major facilitator Superfamily
LFT47_RS06730	COG4770	biotin carboxylase activity
LFT47_RS06735	COG0424	maF-like protein
LFT47_RS06740	COG2409	Drug exporters of the RND superfamily
LFT47_RS06745	COG1309	transcriptional regulator
LFT47_RS06750	COG0393	Putative heavy-metal-binding
LFT47_RS06755	COG1823	symporter activity
LFT47_RS06770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LFT47_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS06805	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LFT47_RS06810	COG0483	inositol monophosphate 1-phosphatase activity
LFT47_RS06815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_RS06820	COG0456	acetyltransferase
LFT47_RS06825	COG0251	oxidation-reduction process
LFT47_RS06830	COG4565	transcriptional regulatory protein
LFT47_RS06835	COG3290	protein histidine kinase activity
LFT47_RS06840	COG2851	Citrate transporter
LFT47_RS06845	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LFT47_RS06850	COG0154	amidase activity
LFT47_RS06855	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LFT47_RS06865	COG1609	Transcriptional regulator
LFT47_RS06875	COG1175	transmembrane transport
LFT47_RS06880	COG0395	ABC-type sugar transport system, permease component
LFT47_RS06900	COG1063	alcohol dehydrogenase
LFT47_RS06905	COG0156	8-amino-7-oxononanoate synthase activity
LFT47_RS06910	COG1486	melibiose metabolic process
LFT47_RS06925	COG1228	amidohydrolase
LFT47_RS06935	COG1846	Transcriptional regulator
LFT47_RS06935	COG1940	carbohydrate kinase activity
LFT47_RS06955	COG0588	phosphoglycerate mutase activity
LFT47_RS06970	COG2873	o-acetylhomoserine
LFT47_RS06975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LFT47_RS07005	COG0423	glycine-tRNA ligase activity
LFT47_RS07025	COG1131	(ABC) transporter
LFT47_RS07030	COG0842	Transport permease protein
LFT47_RS07035	COG4585	Histidine kinase
LFT47_RS07040	COG2197	response regulator
LFT47_RS07055	COG0358	DNA primase activity
LFT47_RS07070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT47_RS07100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LFT47_RS07110	COG0297	glycogen (starch) synthase activity
LFT47_RS07160	COG0052	Belongs to the universal ribosomal protein uS2 family
LFT47_RS07165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LFT47_RS07170	COG0528	UMP kinase activity
LFT47_RS07175	COG0233	cytoplasmic translational termination
LFT47_RS07180	COG0575	Belongs to the CDS family
LFT47_RS07190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LFT47_RS07205	COG3275	phosphorelay sensor kinase activity
LFT47_RS07215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LFT47_RS07230	COG1522	sequence-specific DNA binding
LFT47_RS07240	COG0022	dehydrogenase e1 component
LFT47_RS07245	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_RS07255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LFT47_RS07265	COG1960	acyl-CoA dehydrogenase activity
LFT47_RS07295	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LFT47_RS07300	COG0750	zinc metalloprotease
LFT47_RS07310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LFT47_RS07320	COG1309	transcriptional regulator
LFT47_RS07330	COG1131	(ABC) transporter
LFT47_RS07335	COG0442	prolyl-tRNA aminoacylation
LFT47_RS07345	COG0076	glutamate decarboxylase activity
LFT47_RS07365	COG0779	Required for maturation of 30S ribosomal subunits
LFT47_RS07370	COG0195	Participates in both transcription termination and antitermination
LFT47_RS07380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LFT47_RS07380	COG0481	GTPase activity
LFT47_RS07385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LFT47_RS07390	COG0590	tRNA wobble adenosine to inosine editing
LFT47_RS07395	COG0436	Aminotransferase
LFT47_RS07400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LFT47_RS07420	COG3483	tryptophan 2,3-dioxygenase activity
LFT47_RS07425	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LFT47_RS07430	COG1185	polyribonucleotide nucleotidyltransferase activity
LFT47_RS07435	COG0612	Peptidase, M16
LFT47_RS07460	COG0745	RESPONSE REGULATOR receiver
LFT47_RS07465	COG5002	protein histidine kinase activity
LFT47_RS07480	COG0315	cyclic pyranopterin monophosphate synthase activity
LFT47_RS07485	COG0521	Mo-molybdopterin cofactor biosynthetic process
LFT47_RS07495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LFT47_RS07515	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LFT47_RS07520	COG1674	ftsk spoiiie
LFT47_RS07530	COG1058	Belongs to the CinA family
LFT47_RS07530	COG1546	Belongs to the CinA family
LFT47_RS07535	COG1396	sequence-specific DNA binding
LFT47_RS07550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LFT47_RS07555	COG2137	regulation of response to DNA damage stimulus
LFT47_RS07565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LFT47_RS07570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LFT47_RS07575	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LFT47_RS07580	COG2813	Specifically methylates the guanine in position
LFT47_RS07585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LFT47_RS07595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LFT47_RS07605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LFT47_RS07610	COG0131	Imidazoleglycerol-phosphate dehydratase
LFT47_RS07615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LFT47_RS07625	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LFT47_RS07645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LFT47_RS07650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LFT47_RS07655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LFT47_RS07660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LFT47_RS07670	COG2814	Major facilitator Superfamily
LFT47_RS07685	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LFT47_RS07695	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LFT47_RS07700	COG0072	phenylalanine-tRNA ligase activity
LFT47_RS07700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LFT47_RS07730	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LFT47_RS07735	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LFT47_RS07740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LFT47_RS07745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LFT47_RS07750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LFT47_RS07755	COG1438	arginine binding
LFT47_RS07760	COG0137	argininosuccinate synthase activity
LFT47_RS07765	COG0165	Argininosuccinate lyase
LFT47_RS07780	COG2094	Belongs to the DNA glycosylase MPG family
LFT47_RS07795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LFT47_RS07825	COG0647	UMP catabolic process
LFT47_RS07840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LFT47_RS07845	COG0497	DNA recombination
LFT47_RS07850	COG0504	CTP synthase activity
LFT47_RS07855	COG0494	nUDIX hydrolase
LFT47_RS07880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LFT47_RS07885	COG2079	MmgE PrpD family protein
LFT47_RS07895	COG4565	transcriptional regulatory protein
LFT47_RS07900	COG3290	protein histidine kinase activity
LFT47_RS07905	COG1301	dicarboxylic acid transport
LFT47_RS07915	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LFT47_RS07920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LFT47_RS07930	COG0287	Prephenate dehydrogenase
LFT47_RS07935	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LFT47_RS07945	COG1160	GTP binding
LFT47_RS07960	COG2824	Alkylphosphonate utilization operon protein PhnA
LFT47_RS07970	COG2814	Major facilitator Superfamily
LFT47_RS07975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT47_RS07980	COG0509	glycine decarboxylation via glycine cleavage system
LFT47_RS07985	COG1716	ATPase activity
LFT47_RS08005	COG1192	Involved in chromosome partitioning
LFT47_RS08010	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LFT47_RS08020	COG1940	carbohydrate kinase activity
LFT47_RS08040	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LFT47_RS08050	COG3942	CHAP domain
LFT47_RS08050	COG1388	LysM domain
LFT47_RS08060	COG0142	geranyltranstransferase activity
LFT47_RS08070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LFT47_RS08080	COG2001	Belongs to the MraZ family
LFT47_RS08085	COG0275	rRNA processing
LFT47_RS08095	COG0768	penicillin binding
LFT47_RS08100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LFT47_RS08110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LFT47_RS08115	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LFT47_RS08120	COG0772	Belongs to the SEDS family
LFT47_RS08125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LFT47_RS08130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LFT47_RS08135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LFT47_RS08140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LFT47_RS08150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LFT47_RS08155	COG1799	cell septum assembly
LFT47_RS08170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LFT47_RS08180	COG0587	DNA-directed DNA polymerase activity
LFT47_RS08195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LFT47_RS08200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LFT47_RS08205	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS08225	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LFT47_RS08230	COG0174	glutamine synthetase
LFT47_RS08235	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LFT47_RS08275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LFT47_RS08280	COG0321	lipoyl(octanoyl) transferase activity
LFT47_RS08285	COG0515	serine threonine protein kinase
LFT47_RS08290	COG1090	epimerase
LFT47_RS08295	COG0793	Belongs to the peptidase S41A family
LFT47_RS08295	COG4946	Tricorn protease homolog
LFT47_RS08300	COG1764	response to oxidative stress
LFT47_RS08310	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_RS08315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LFT47_RS08320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LFT47_RS08340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LFT47_RS08345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LFT47_RS08380	COG1271	oxidase subunit
LFT47_RS08385	COG1294	oxidase, subunit
LFT47_RS08390	COG4988	ABC transporter
LFT47_RS08410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LFT47_RS08430	COG1435	thymidine kinase activity
LFT47_RS08450	COG0756	dUTP diphosphatase activity
LFT47_RS08475	COG0569	domain protein
LFT47_RS08480	COG0531	amino acid
LFT47_RS08485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LFT47_RS08490	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LFT47_RS08495	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LFT47_RS08510	COG0667	Aldo Keto reductase
LFT47_RS08520	COG1024	Enoyl-CoA hydratase
LFT47_RS08520	COG1250	3-hydroxyacyl-CoA dehydrogenase
LFT47_RS08525	COG0183	Belongs to the thiolase family
LFT47_RS08555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LFT47_RS08570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LFT47_RS08590	COG3135	benzoate transporter
LFT47_RS08600	COG0531	amino acid
LFT47_RS08640	COG3706	GGDEF domain
LFT47_RS08650	COG0242	peptide deformylase activity
LFT47_RS08655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LFT47_RS08665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LFT47_RS08685	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LFT47_RS08685	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LFT47_RS08690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LFT47_RS08690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LFT47_RS08695	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LFT47_RS08700	COG0140	phosphoribosyl-ATP diphosphatase activity
LFT47_RS08705	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LFT47_RS08710	COG0107	imidazoleglycerol-phosphate synthase activity
LFT47_RS08720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LFT47_RS08740	COG0134	indole-3-glycerol-phosphate synthase activity
LFT47_RS08745	COG0133	tryptophan synthase activity
LFT47_RS08750	COG0159	tryptophan synthase activity
LFT47_RS08755	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LFT47_RS08760	COG0067	glutamate synthase
LFT47_RS08760	COG0070	glutamate synthase
LFT47_RS08760	COG0069	glutamate synthase activity
LFT47_RS08790	COG2186	Transcriptional regulator
LFT47_RS08820	COG1177	transmembrane transport
LFT47_RS08835	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_RS08840	COG3618	amidohydrolase
LFT47_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS08890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LFT47_RS08900	COG0183	Belongs to the thiolase family
LFT47_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS08930	COG2814	Major facilitator Superfamily
LFT47_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS08960	COG0667	Aldo Keto reductase
LFT47_RS08965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LFT47_RS08970	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LFT47_RS08980	COG2188	Transcriptional regulator
LFT47_RS08985	COG1960	acyl-CoA dehydrogenase activity
LFT47_RS08990	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS09005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LFT47_RS09010	COG0318	PFAM AMP-dependent synthetase and ligase
LFT47_RS09035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LFT47_RS09045	COG2186	Transcriptional regulator
LFT47_RS09085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_RS09090	COG0444	Belongs to the ABC transporter superfamily
LFT47_RS09095	COG4608	Belongs to the ABC transporter superfamily
LFT47_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS09125	COG4166	transmembrane transport
LFT47_RS09175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_RS09180	COG0444	Belongs to the ABC transporter superfamily
LFT47_RS09185	COG4608	Belongs to the ABC transporter superfamily
LFT47_RS09195	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LFT47_RS09200	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LFT47_RS09230	COG2072	flavoprotein involved in K transport
LFT47_RS09235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LFT47_RS09260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LFT47_RS09275	COG1024	Enoyl-CoA hydratase
LFT47_RS09290	COG0183	Belongs to the thiolase family
LFT47_RS09300	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LFT47_RS09310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LFT47_RS09315	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS09325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LFT47_RS09350	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS09360	COG0512	Glutamine amidotransferase of anthranilate synthase
LFT47_RS09360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LFT47_RS09370	COG1609	Transcriptional regulator
LFT47_RS09395	COG0667	Aldo Keto reductase
LFT47_RS09420	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS09425	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LFT47_RS09435	COG1414	Transcriptional regulator
LFT47_RS09450	COG2814	Major facilitator Superfamily
LFT47_RS09470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT47_RS09480	COG4638	Rieske (2fe-2S)
LFT47_RS09550	COG3654	unkown
LFT47_RS09560	COG0583	DNA-binding transcription factor activity
LFT47_RS09565	COG2828	Protein conserved in bacteria
LFT47_RS09570	COG1301	dicarboxylic acid transport
LFT47_RS09595	COG0800	Aldolase
LFT47_RS09605	COG1609	Transcriptional regulator
LFT47_RS09620	COG0673	inositol 2-dehydrogenase activity
LFT47_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS09650	COG1309	transcriptional regulator
LFT47_RS09660	COG3321	synthase
LFT47_RS09660	COG0604	alcohol dehydrogenase
LFT47_RS09670	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_RS09675	COG0154	amidase activity
LFT47_RS09680	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_RS09685	COG1129	ABC transporter
LFT47_RS09705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LFT47_RS09710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT47_RS09725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LFT47_RS09730	COG0251	oxidation-reduction process
LFT47_RS09735	COG0477	Major facilitator Superfamily
LFT47_RS09745	COG0477	Major facilitator Superfamily
LFT47_RS09750	COG0028	Belongs to the TPP enzyme family
LFT47_RS09755	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS09760	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LFT47_RS09765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT47_RS09785	COG0477	Major facilitator Superfamily
LFT47_RS09790	COG1063	alcohol dehydrogenase
LFT47_RS09795	COG0246	Mannitol dehydrogenase
LFT47_RS09800	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_RS09805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LFT47_RS09810	COG1609	Transcriptional regulator
LFT47_RS09870	COG3654	unkown
LFT47_RS09875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LFT47_RS09895	COG1621	beta-fructofuranosidase activity
LFT47_RS09900	COG0395	ABC-type sugar transport system, permease component
LFT47_RS09915	COG1609	Transcriptional regulator
LFT47_RS09935	COG0667	Aldo Keto reductase
LFT47_RS09950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LFT47_RS09960	COG1335	isochorismatase
LFT47_RS09990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LFT47_RS09995	COG0443	Heat shock 70 kDa protein
LFT47_RS10000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LFT47_RS10015	COG0542	response to heat
LFT47_RS10025	COG0288	reversible hydration of carbon dioxide
LFT47_RS10030	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LFT47_RS10040	COG2200	EAL domain
LFT47_RS10050	COG1609	Transcriptional regulator
LFT47_RS10055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT47_RS10060	COG0698	ribose 5-phosphate isomerase
LFT47_RS10065	COG0477	Major facilitator Superfamily
LFT47_RS10070	COG0667	Aldo Keto reductase
LFT47_RS10075	COG0667	Aldo Keto reductase
LFT47_RS10090	COG0515	serine threonine protein kinase
LFT47_RS10110	COG5416	Lipopolysaccharide assembly protein A domain
LFT47_RS10115	COG1295	ribonuclease BN
LFT47_RS10155	COG0484	heat shock protein binding
LFT47_RS10160	COG0071	Belongs to the small heat shock protein (HSP20) family
LFT47_RS10165	COG0789	Transcriptional regulator
LFT47_RS10170	COG1396	sequence-specific DNA binding
LFT47_RS10180	COG0667	Aldo Keto reductase
LFT47_RS10205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LFT47_RS10235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LFT47_RS10245	COG0688	phosphatidylethanolamine metabolic process
LFT47_RS10330	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LFT47_RS10340	COG0543	2 iron, 2 sulfur cluster binding
LFT47_RS10340	COG0633	Ferredoxin
LFT47_RS10345	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LFT47_RS10375	COG3118	belongs to the thioredoxin family
LFT47_RS10380	COG0789	Transcriptional regulator
LFT47_RS10405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LFT47_RS10410	COG0667	Aldo Keto reductase
LFT47_RS10420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LFT47_RS10450	COG1131	(ABC) transporter
LFT47_RS10485	COG3795	YCII-related domain
LFT47_RS10490	COG4941	Belongs to the sigma-70 factor family
LFT47_RS10510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT47_RS10555	COG1309	transcriptional regulator
LFT47_RS10565	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT47_RS10590	COG4632	Exopolysaccharide biosynthesis protein
LFT47_RS10590	COG5434	Belongs to the glycosyl hydrolase 28 family
LFT47_RS10595	COG0598	Magnesium transport protein CorA
LFT47_RS10605	COG0318	PFAM AMP-dependent synthetase and ligase
LFT47_RS10655	COG3387	PFAM Glycoside hydrolase 15-related
LFT47_RS10665	COG1609	Transcriptional regulator
LFT47_RS10680	COG2160	L-arabinose isomerase activity
LFT47_RS10695	COG3534	alpha-L-arabinofuranosidase
LFT47_RS10700	COG0395	ABC-type sugar transport system, permease component
LFT47_RS10740	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS10760	COG3226	Transcriptional regulator
LFT47_RS10770	COG4952	isomerase
LFT47_RS10775	COG3347	Dehydrogenase
LFT47_RS10775	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS10780	COG1070	Carbohydrate kinase
LFT47_RS10790	COG2814	Major facilitator Superfamily
LFT47_RS10835	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS10840	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS10845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LFT47_RS10850	COG1024	Enoyl-CoA hydratase
LFT47_RS10855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LFT47_RS10865	COG1396	sequence-specific DNA binding
LFT47_RS10870	COG0477	Major facilitator Superfamily
LFT47_RS10880	COG3422	double-strand break repair
LFT47_RS10895	COG0515	serine threonine protein kinase
LFT47_RS10900	COG0405	Gamma-glutamyltransferase
LFT47_RS10920	COG3959	Transketolase, thiamine diphosphate binding domain
LFT47_RS10940	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS11005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LFT47_RS11015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LFT47_RS11025	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LFT47_RS11045	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LFT47_RS11050	COG0217	transcriptional regulatory protein
LFT47_RS11055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LFT47_RS11060	COG0632	four-way junction helicase activity
LFT47_RS11065	COG2255	four-way junction helicase activity
LFT47_RS11075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LFT47_RS11080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LFT47_RS11085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LFT47_RS11095	COG1196	nuclear chromosome segregation
LFT47_RS11105	COG0124	histidyl-tRNA synthetase
LFT47_RS11110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LFT47_RS11135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LFT47_RS11150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LFT47_RS11165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFT47_RS11170	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LFT47_RS11175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LFT47_RS11180	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LFT47_RS11190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LFT47_RS11195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LFT47_RS11200	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LFT47_RS11205	COG0540	Belongs to the ATCase OTCase family
LFT47_RS11210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT47_RS11220	COG0505	Belongs to the CarA family
LFT47_RS11225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LFT47_RS11230	COG0284	orotidine-5'-phosphate decarboxylase activity
LFT47_RS11240	COG0194	GDP metabolic process
LFT47_RS11245	COG1758	RNA polymerase activity
LFT47_RS11255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LFT47_RS11265	COG0438	transferase activity, transferring glycosyl groups
LFT47_RS11275	COG0656	L-ascorbic acid biosynthetic process
LFT47_RS11280	COG2390	Transcriptional regulator
LFT47_RS11285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LFT47_RS11290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LFT47_RS11295	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LFT47_RS11300	COG0495	leucyl-tRNA aminoacylation
LFT47_RS11305	COG1307	EDD domain protein, DegV family
LFT47_RS11315	COG1555	photosystem II stabilization
LFT47_RS11400	COG0768	penicillin binding
LFT47_RS11410	COG0166	Belongs to the GPI family
LFT47_RS11460	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LFT47_RS11500	COG0268	Binds directly to 16S ribosomal RNA
LFT47_RS11510	COG0481	GTPase activity
LFT47_RS11515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LFT47_RS11530	COG1420	regulation of RNA biosynthetic process
LFT47_RS11535	COG0484	heat shock protein binding
LFT47_RS11540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LFT47_RS11555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LFT47_RS11565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LFT47_RS11570	COG1316	TRANSCRIPTIONal
LFT47_RS11575	COG3590	peptidase
LFT47_RS11580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LFT47_RS11585	COG1381	Involved in DNA repair and RecF pathway recombination
LFT47_RS11590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LFT47_RS11595	COG2267	carboxylic ester hydrolase activity
LFT47_RS11610	COG0167	dihydroorotate dehydrogenase activity
LFT47_RS11630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LFT47_RS11635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LFT47_RS11645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT47_RS11650	COG2188	Transcriptional regulator
LFT47_RS11655	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LFT47_RS11660	COG0723	plastoquinol--plastocyanin reductase activity
LFT47_RS11665	COG2010	Cytochrome c
LFT47_RS11670	COG1845	cytochrome c oxidase, subunit III
LFT47_RS11675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LFT47_RS11700	COG1316	TRANSCRIPTIONal
LFT47_RS11705	COG1280	lysine exporter protein (LysE YggA)
LFT47_RS11715	COG2197	response regulator
LFT47_RS11725	COG3559	Exporter of polyketide antibiotics
LFT47_RS11730	COG1131	(ABC) transporter
LFT47_RS11735	COG0596	Alpha beta hydrolase
LFT47_RS11750	COG1335	isochorismatase
LFT47_RS11760	COG0384	phenazine biosynthesis protein PhzF
LFT47_RS11770	COG4974	Belongs to the 'phage' integrase family
LFT47_RS11815	COG3424	synthase
LFT47_RS11820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LFT47_RS11830	COG0242	peptide deformylase activity
LFT47_RS11835	COG1506	peptidase
LFT47_RS11835	COG0823	Involved in the tonB-independent uptake of proteins
LFT47_RS11835	COG4946	Tricorn protease homolog
LFT47_RS11860	COG1216	Glycosyl transferase, family 2
LFT47_RS11865	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LFT47_RS11870	COG4581	dead DEAH box helicase
LFT47_RS11875	COG0805	protein transport
LFT47_RS11880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LFT47_RS11900	COG0545	Peptidyl-prolyl cis-trans isomerase
LFT47_RS11905	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LFT47_RS11910	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LFT47_RS11915	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LFT47_RS11925	COG4122	O-methyltransferase activity
LFT47_RS11930	COG1222	aaa ATPase
LFT47_RS11940	COG1994	Peptidase M50
LFT47_RS11940	COG0517	IMP dehydrogenase activity
LFT47_RS11945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LFT47_RS11955	COG0215	cysteine-tRNA ligase activity
LFT47_RS11960	COG1968	undecaprenyl-diphosphatase activity
LFT47_RS11965	COG0656	L-ascorbic acid biosynthetic process
LFT47_RS11985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT47_RS12000	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS12020	COG0297	glycogen (starch) synthase activity
LFT47_RS12025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LFT47_RS12050	COG2855	membrane
LFT47_RS12075	COG0254	rRNA binding
LFT47_RS12090	COG1119	ATPase activity
LFT47_RS12095	COG3830	Belongs to the UPF0237 family
LFT47_RS12095	COG0560	Phosphoserine phosphatase
LFT47_RS12100	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS12105	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS12135	COG0488	(ABC) transporter
LFT47_RS12145	COG1268	BioY protein
LFT47_RS12150	COG1122	ATPase activity
LFT47_RS12165	COG0318	PFAM AMP-dependent synthetase and ligase
LFT47_RS12170	COG2151	metal-sulfur cluster biosynthetic enzyme
LFT47_RS12175	COG0396	ATPase activity
LFT47_RS12200	COG1131	(ABC) transporter
LFT47_RS12210	COG1612	heme a metabolic process
LFT47_RS12215	COG0109	protoheme IX farnesyltransferase activity
LFT47_RS12225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LFT47_RS12230	COG0166	Belongs to the GPI family
LFT47_RS12245	COG0363	glucosamine-6-phosphate deaminase activity
LFT47_RS12255	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LFT47_RS12260	COG0149	triose-phosphate isomerase activity
LFT47_RS12265	COG0126	phosphoglycerate kinase activity
LFT47_RS12270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LFT47_RS12275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LFT47_RS12280	COG1481	regulation of sporulation
LFT47_RS12285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LFT47_RS12290	COG1660	Displays ATPase and GTPase activities
LFT47_RS12295	COG0322	excinuclease ABC activity
LFT47_RS12305	COG0546	phosphoglycolate phosphatase activity
LFT47_RS12330	COG4106	trans-aconitate 2-methyltransferase activity
LFT47_RS12350	COG2814	Major facilitator Superfamily
LFT47_RS12360	COG0556	nucleotide-excision repair
LFT47_RS12370	COG0237	dephospho-CoA kinase activity
LFT47_RS12370	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LFT47_RS12375	COG1739	Uncharacterized protein family UPF0029
LFT47_RS12380	COG0539	negative regulation of cytoplasmic translation
LFT47_RS12390	COG4552	Acetyltransferase involved in intracellular survival and related
LFT47_RS12400	COG2050	protein possibly involved in aromatic compounds catabolism
LFT47_RS12405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LFT47_RS12425	COG3483	tryptophan 2,3-dioxygenase activity
LFT47_RS12460	COG0009	L-threonylcarbamoyladenylate synthase
LFT47_RS12480	COG1643	Atp-dependent helicase
LFT47_RS12515	COG1064	alcohol dehydrogenase
LFT47_RS12520	COG0477	Major facilitator Superfamily
LFT47_RS12525	COG1609	Transcriptional regulator
LFT47_RS12545	COG0492	ferredoxin-NADP+ reductase activity
LFT47_RS12560	COG2814	Major facilitator Superfamily
LFT47_RS12600	COG4804	nuclease activity
LFT47_RS12615	COG0412	Dienelactone hydrolase
LFT47_RS12620	COG1234	tRNA 3'-trailer cleavage
LFT47_RS12665	COG0667	Aldo Keto reductase
LFT47_RS12670	COG1501	Belongs to the glycosyl hydrolase 31 family
LFT47_RS12675	COG3387	PFAM Glycoside hydrolase 15-related
LFT47_RS12685	COG0395	ABC-type sugar transport system, permease component
LFT47_RS12690	COG1175	transmembrane transport
LFT47_RS12695	COG1940	carbohydrate kinase activity
LFT47_RS12695	COG1846	Transcriptional regulator
LFT47_RS12700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LFT47_RS12705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LFT47_RS12710	COG1780	Probably involved in ribonucleotide reductase function
LFT47_RS12720	COG0583	DNA-binding transcription factor activity
LFT47_RS12730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LFT47_RS12735	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LFT47_RS12750	COG1175	transmembrane transport
LFT47_RS12755	COG1653	transport
LFT47_RS12800	COG1309	transcriptional regulator
LFT47_RS12805	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS12815	COG0477	Major facilitator Superfamily
LFT47_RS12820	COG1957	nucleoside hydrolase
LFT47_RS12830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT47_RS12840	COG2957	Belongs to the agmatine deiminase family
LFT47_RS12845	COG0154	amidase activity
LFT47_RS12850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LFT47_RS12870	COG0444	Belongs to the ABC transporter superfamily
LFT47_RS12905	COG0587	DNA-directed DNA polymerase activity
LFT47_RS12915	COG0673	inositol 2-dehydrogenase activity
LFT47_RS12930	COG1609	Transcriptional regulator
LFT47_RS12970	COG0799	negative regulation of ribosome biogenesis
LFT47_RS12980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LFT47_RS12990	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LFT47_RS12995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LFT47_RS13000	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LFT47_RS13005	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LFT47_RS13010	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LFT47_RS13015	COG0351	phosphomethylpyrimidine kinase
LFT47_RS13015	COG0352	thiamine-phosphate diphosphorylase activity
LFT47_RS13015	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LFT47_RS13020	COG1530	ribonuclease E activity
LFT47_RS13030	COG0105	UTP biosynthetic process
LFT47_RS13040	COG0285	dihydrofolate synthase activity
LFT47_RS13045	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LFT47_RS13055	COG0525	valine-tRNA ligase activity
LFT47_RS13060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT47_RS13065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LFT47_RS13070	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LFT47_RS13075	COG0740	serine-type endopeptidase activity
LFT47_RS13080	COG0740	serine-type endopeptidase activity
LFT47_RS13085	COG0544	peptidyl-prolyl cis-trans isomerase activity
LFT47_RS13125	COG0668	transmembrane transport
LFT47_RS13140	COG1946	Acyl-CoA thioesterase
LFT47_RS13170	COG0024	Methionine aminopeptidase
LFT47_RS13210	COG0242	peptide deformylase activity
LFT47_RS13240	COG3022	response to hydroperoxide
LFT47_RS13250	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LFT47_RS13255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LFT47_RS13265	COG1045	serine acetyltransferase
LFT47_RS13270	COG0300	oxidoreductase activity
LFT47_RS13275	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LFT47_RS13285	COG1063	alcohol dehydrogenase
LFT47_RS13290	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS13300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT47_RS13305	COG0477	Major facilitator Superfamily
LFT47_RS13310	COG1414	Transcriptional regulator
LFT47_RS13320	COG2188	Transcriptional regulator
LFT47_RS13340	COG3842	ATPase activity
LFT47_RS13375	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LFT47_RS13390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LFT47_RS13395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LFT47_RS13410	COG4974	Belongs to the 'phage' integrase family
LFT47_RS13425	COG0792	nuclease activity
LFT47_RS13435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LFT47_RS13445	COG0681	Belongs to the peptidase S26 family
LFT47_RS13450	COG0335	large ribosomal subunit rRNA binding
LFT47_RS13455	COG0336	Belongs to the RNA methyltransferase TrmD family
LFT47_RS13460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LFT47_RS13465	COG1837	Belongs to the UPF0109 family
LFT47_RS13470	COG0228	four-way junction DNA binding
LFT47_RS13480	COG2514	catechol 2,3-dioxygenase activity
LFT47_RS13505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LFT47_RS13520	COG2814	Major facilitator Superfamily
LFT47_RS13535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT47_RS13540	COG0571	ribonuclease III activity
LFT47_RS13545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LFT47_RS13555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LFT47_RS13570	COG0742	ribosomal rna small subunit methyltransferase
LFT47_RS13595	COG1181	Belongs to the D-alanine--D-alanine ligase family
LFT47_RS13600	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LFT47_RS13610	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LFT47_RS13615	COG0066	3-isopropylmalate dehydratase activity
LFT47_RS13620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LFT47_RS13625	COG1414	Transcriptional regulator
LFT47_RS13655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LFT47_RS13660	COG0179	Fumarylacetoacetate (FAA) hydrolase
LFT47_RS13665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT47_RS13675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LFT47_RS13680	COG0473	3-isopropylmalate dehydrogenase activity
LFT47_RS13700	COG0577	efflux transmembrane transporter activity
LFT47_RS13700	COG1136	(ABC) transporter
LFT47_RS13710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT47_RS13715	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LFT47_RS13720	COG0440	acetolactate synthase activity
LFT47_RS13730	COG0129	dihydroxy-acid dehydratase activity
LFT47_RS13740	COG2133	pyrroloquinoline quinone binding
LFT47_RS13770	COG0747	negative chemotaxis
LFT47_RS13775	COG0579	oxidoreductase
LFT47_RS13780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LFT47_RS13785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_RS13795	COG1305	Transglutaminase-like
LFT47_RS13820	COG1104	cysteine desulfurase activity
LFT47_RS13830	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LFT47_RS13835	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LFT47_RS13850	COG1113	amino acid transport
LFT47_RS13860	COG0022	dehydrogenase e1 component
LFT47_RS13865	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_RS13895	COG1414	Transcriptional regulator
LFT47_RS13905	COG0419	ATPase involved in DNA repair
LFT47_RS13910	COG0420	3'-5' exonuclease activity
LFT47_RS13915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LFT47_RS13925	COG2149	membrane
LFT47_RS13955	COG0586	Pfam SNARE associated Golgi protein
LFT47_RS13960	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LFT47_RS13965	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LFT47_RS13970	COG1234	tRNA 3'-trailer cleavage
LFT47_RS13975	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LFT47_RS13985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LFT47_RS13995	COG1335	isochorismatase
LFT47_RS14010	COG0363	glucosamine-6-phosphate deaminase activity
LFT47_RS14025	COG1902	pentaerythritol trinitrate reductase activity
LFT47_RS14055	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LFT47_RS14060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LFT47_RS14070	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LFT47_RS14085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LFT47_RS14090	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LFT47_RS14095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LFT47_RS14100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LFT47_RS14105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LFT47_RS14110	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LFT47_RS14115	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LFT47_RS14120	COG0356	it plays a direct role in the translocation of protons across the membrane
LFT47_RS14155	COG2890	protein-(glutamine-N5) methyltransferase activity
LFT47_RS14160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LFT47_RS14170	COG0083	homoserine kinase activity
LFT47_RS14175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LFT47_RS14180	COG0460	homoserine dehydrogenase
LFT47_RS14185	COG0019	diaminopimelate decarboxylase activity
LFT47_RS14190	COG0018	arginyl-trna synthetase
LFT47_RS14240	COG1643	Atp-dependent helicase
LFT47_RS14250	COG1064	alcohol dehydrogenase
LFT47_RS14275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LFT47_RS14280	COG1121	(ABC) transporter
LFT47_RS14295	COG1253	flavin adenine dinucleotide binding
LFT47_RS14300	COG0567	Dehydrogenase, E1 component
LFT47_RS14300	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_RS14325	COG1595	DNA-templated transcription, initiation
LFT47_RS14335	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LFT47_RS14345	COG0483	inositol monophosphate 1-phosphatase activity
LFT47_RS14350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LFT47_RS14390	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS14400	COG1960	acyl-CoA dehydrogenase activity
LFT47_RS14410	COG0477	Major facilitator Superfamily
LFT47_RS14420	COG0701	Predicted permease
LFT47_RS14440	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LFT47_RS14450	COG2177	Part of the ABC transporter FtsEX involved in
LFT47_RS14455	COG2884	Cell division ATP-binding protein ftsE
LFT47_RS14460	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LFT47_RS14595	COG0463	Glycosyl transferase, family 2
LFT47_RS14605	COG0463	Glycosyl transferase, family 2
LFT47_RS14620	COG2755	lipolytic protein G-D-S-L family
LFT47_RS14620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LFT47_RS14645	COG1216	Glycosyl transferase, family 2
LFT47_RS14675	COG2902	Dehydrogenase
LFT47_RS14710	COG0653	protein targeting
LFT47_RS14715	COG3214	Protein conserved in bacteria
LFT47_RS14720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LFT47_RS14730	COG5401	PFAM Sporulation and spore germination
LFT47_RS14735	COG5002	protein histidine kinase activity
LFT47_RS14760	COG0714	Associated with various cellular activities
LFT47_RS14795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_RS14800	COG0601	transmembrane transport
LFT47_RS14810	COG0482	sulfurtransferase activity
LFT47_RS14835	COG0484	heat shock protein binding
LFT47_RS14840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LFT47_RS14850	COG5343	regulation of RNA biosynthetic process
LFT47_RS14865	COG3265	gluconokinase activity
LFT47_RS14875	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LFT47_RS14880	COG2086	electron transfer activity
LFT47_RS14885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LFT47_RS14895	COG1842	Phage shock protein A
LFT47_RS14900	COG1960	acyl-CoA dehydrogenase activity
LFT47_RS14910	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LFT47_RS14960	COG1615	UPF0182 protein
LFT47_RS14965	COG3480	Lon protease (S16) C-terminal proteolytic domain
LFT47_RS14985	COG2816	NAD+ diphosphatase activity
LFT47_RS14995	COG0210	DNA helicase
LFT47_RS15015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT47_RS15020	COG0765	amino acid transport
LFT47_RS15025	COG1126	abc transporter atp-binding protein
LFT47_RS15030	COG1472	Belongs to the glycosyl hydrolase 3 family
LFT47_RS15035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LFT47_RS15045	COG0113	porphobilinogen synthase activity
LFT47_RS15055	COG0181	hydroxymethylbilane synthase activity
LFT47_RS15060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LFT47_RS15065	COG3253	May function as heme-dependent peroxidase
LFT47_RS15075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LFT47_RS15080	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LFT47_RS15110	COG2154	pterin-4-alpha-carbinolamine dehydratase
LFT47_RS15115	COG2022	thiamine diphosphate biosynthetic process
LFT47_RS15125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LFT47_RS15125	COG2022	thiamine diphosphate biosynthetic process
LFT47_RS15130	COG0352	thiamine-phosphate diphosphorylase activity
LFT47_RS15135	COG0557	exoribonuclease II activity
LFT47_RS15140	COG0513	Belongs to the DEAD box helicase family
LFT47_RS15145	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LFT47_RS15150	COG0613	PHP domain protein
LFT47_RS15155	COG0006	proline dipeptidase activity
LFT47_RS15165	COG0577	efflux transmembrane transporter activity
LFT47_RS15165	COG1136	(ABC) transporter
LFT47_RS15175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LFT47_RS15185	COG2239	Acts as a magnesium transporter
LFT47_RS15210	COG1595	DNA-templated transcription, initiation
LFT47_RS15240	COG1126	abc transporter atp-binding protein
LFT47_RS15245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT47_RS15250	COG0765	amino acid transport
LFT47_RS15255	COG0765	amino acid transport
LFT47_RS15260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT47_RS15265	COG2171	N-acyltransferase activity
LFT47_RS15280	COG3226	Transcriptional regulator
LFT47_RS15285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LFT47_RS15330	COG1217	gtp-binding protein TYPA
LFT47_RS15340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_RS15345	COG0601	transmembrane transport
LFT47_RS15350	COG4166	transmembrane transport
LFT47_RS15370	COG0601	transmembrane transport
LFT47_RS15375	COG4166	transmembrane transport
LFT47_RS15390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LFT47_RS15415	COG0012	GTP binding
LFT47_RS15425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LFT47_RS15435	COG1570	exodeoxyribonuclease VII activity
LFT47_RS15440	COG1722	exodeoxyribonuclease VII activity
LFT47_RS15445	COG2326	polyphosphate kinase activity
LFT47_RS15460	COG1174	glycine betaine transport
LFT47_RS15465	COG1174	glycine betaine transport
LFT47_RS15485	COG2971	BadF BadG BcrA BcrD
LFT47_RS15490	COG0583	DNA-binding transcription factor activity
LFT47_RS15495	COG2814	Major facilitator Superfamily
LFT47_RS15500	COG0626	cystathionine gamma-synthase activity
LFT47_RS15535	COG0598	Magnesium transport protein CorA
LFT47_RS15550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LFT47_RS15555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LFT47_RS15560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LFT47_RS15585	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_RS15595	COG0246	Mannitol dehydrogenase
LFT47_RS15600	COG1904	glucuronate isomerase
LFT47_RS15605	COG1609	Transcriptional regulator
LFT47_RS15610	COG0673	inositol 2-dehydrogenase activity
LFT47_RS15645	COG3265	gluconokinase activity
LFT47_RS15695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LFT47_RS15700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LFT47_RS15720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LFT47_RS15720	COG0519	Catalyzes the synthesis of GMP from XMP
LFT47_RS15740	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LFT47_RS15745	COG0516	GMP reductase activity
LFT47_RS15760	COG0459	protein refolding
LFT47_RS15765	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LFT47_RS15780	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFT47_RS15785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LFT47_RS15795	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT47_RS15800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LFT47_RS15815	COG0802	atpase or kinase
LFT47_RS15820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LFT47_RS15835	COG0438	transferase activity, transferring glycosyl groups
LFT47_RS15840	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LFT47_RS15855	COG0667	Aldo Keto reductase
LFT47_RS15885	COG0736	holo-[acyl-carrier-protein] synthase activity
LFT47_RS15895	COG1072	(Pantothenic acid kinase))
LFT47_RS15900	COG1876	peptidase activity
LFT47_RS15905	COG1970	mechanosensitive ion channel activity
LFT47_RS15910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LFT47_RS15915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LFT47_RS15915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LFT47_RS15920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LFT47_RS15925	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LFT47_RS15965	COG2894	cell division
LFT47_RS15985	COG0101	tRNA pseudouridine synthase activity
LFT47_RS15990	COG0203	ribosomal protein L17
LFT47_RS15995	COG0202	RNA polymerase activity
LFT47_RS16000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LFT47_RS16005	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LFT47_RS16010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LFT47_RS16015	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LFT47_RS16020	COG3191	aminopeptidase activity
LFT47_RS16030	COG0747	negative chemotaxis
LFT47_RS16045	COG0601	transmembrane transport
LFT47_RS16050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_RS16060	COG2186	Transcriptional regulator
LFT47_RS16070	COG1175	transmembrane transport
LFT47_RS16085	COG0024	Methionine aminopeptidase
LFT47_RS16090	COG0563	adenylate kinase activity
LFT47_RS16100	COG0200	Binds to the 23S rRNA
LFT47_RS16105	COG1841	ribosomal large subunit assembly
LFT47_RS16110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LFT47_RS16120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LFT47_RS16125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LFT47_RS16130	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LFT47_RS16135	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LFT47_RS16140	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LFT47_RS16145	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LFT47_RS16155	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LFT47_RS16160	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LFT47_RS16165	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LFT47_RS16170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LFT47_RS16175	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LFT47_RS16180	COG0089	rRNA binding
LFT47_RS16185	COG0088	Forms part of the polypeptide exit tunnel
LFT47_RS16190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LFT47_RS16195	COG0051	transcription antitermination factor activity, RNA binding
LFT47_RS16200	COG2723	6-phospho-beta-galactosidase activity
LFT47_RS16210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LFT47_RS16215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LFT47_RS16220	COG0049	tRNA binding
LFT47_RS16225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LFT47_RS16230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LFT47_RS16235	COG0085	RNA polymerase activity
LFT47_RS16240	COG0183	Belongs to the thiolase family
LFT47_RS16245	COG0442	prolyl-tRNA aminoacylation
LFT47_RS16250	COG0222	ribosome binding
LFT47_RS16255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LFT47_RS16270	COG0081	regulation of translation
LFT47_RS16275	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LFT47_RS16295	COG0436	Aminotransferase
LFT47_RS16300	COG2197	response regulator
LFT47_RS16350	COG0354	folic acid binding
LFT47_RS16360	COG3485	protocatechuate 3,4-dioxygenase
LFT47_RS16370	COG0745	RESPONSE REGULATOR receiver
LFT47_RS16375	COG0456	acetyltransferase
LFT47_RS16380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LFT47_RS16390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LFT47_RS16405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LFT47_RS16420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LFT47_RS16425	COG0738	Major facilitator superfamily
LFT47_RS16430	COG2030	dehydratase
LFT47_RS16435	COG2030	dehydratase
LFT47_RS16465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LFT47_RS16475	COG4989	oxidoreductase activity
LFT47_RS16480	COG0366	Alpha amylase catalytic
LFT47_RS16485	COG1940	carbohydrate kinase activity
LFT47_RS16500	COG3942	CHAP domain
LFT47_RS16500	COG1388	LysM domain
LFT47_RS16590	COG0318	PFAM AMP-dependent synthetase and ligase
LFT47_RS16600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LFT47_RS16625	COG1666	GTP binding
LFT47_RS16630	COG0672	)-iron permease
LFT47_RS16640	COG2837	iron assimilation
LFT47_RS16645	COG0501	Belongs to the peptidase M48B family
LFT47_RS16650	COG0531	amino acid
LFT47_RS16670	COG0531	amino acid
LFT47_RS16715	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS16720	COG2508	Transcriptional regulator
LFT47_RS16720	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LFT47_RS16735	COG2807	transmembrane transport
LFT47_RS16740	COG2186	Transcriptional regulator
LFT47_RS16745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT47_RS16745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LFT47_RS16755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LFT47_RS16755	COG1648	precorrin-2 dehydrogenase activity
LFT47_RS16760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_RS16770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LFT47_RS16790	COG0175	sulfate reduction
LFT47_RS16795	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LFT47_RS16805	COG2860	membrane
LFT47_RS16820	COG0142	geranyltranstransferase activity
LFT47_RS16825	COG0644	oxidoreductase
LFT47_RS16830	COG2226	methyltransferase
LFT47_RS16835	COG1169	isochorismate synthase
LFT47_RS16845	COG0765	amino acid transport
LFT47_RS16860	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LFT47_RS16870	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_RS16880	COG1609	Transcriptional regulator
LFT47_RS16890	COG0395	ABC-type sugar transport system, permease component
LFT47_RS16895	COG1175	transmembrane transport
LFT47_RS16950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFT47_RS16960	COG0640	Transcriptional regulator
LFT47_RS16965	COG0702	epimerase
LFT47_RS16975	COG3979	chitinase
LFT47_RS16985	COG0640	Transcriptional regulator
LFT47_RS17000	COG2814	Major facilitator Superfamily
LFT47_RS17030	COG2200	EAL domain
LFT47_RS17030	COG3287	FIST C domain
LFT47_RS17030	COG2199	diguanylate cyclase activity
LFT47_RS17035	COG1309	transcriptional regulator
LFT47_RS17070	COG0745	RESPONSE REGULATOR receiver
LFT47_RS17070	COG2205	protein histidine kinase activity
LFT47_RS17070	COG4191	Histidine kinase
LFT47_RS17095	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_RS17100	COG0022	dehydrogenase e1 component
LFT47_RS17120	COG0489	protein tyrosine kinase activity
LFT47_RS17155	COG0438	transferase activity, transferring glycosyl groups
LFT47_RS17170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LFT47_RS17185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFT47_RS17190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LFT47_RS17210	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LFT47_RS17215	COG1316	TRANSCRIPTIONal
LFT47_RS17225	COG0640	Transcriptional regulator
LFT47_RS17250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT47_RS17255	COG2151	metal-sulfur cluster biosynthetic enzyme
LFT47_RS17260	COG3396	Phenylacetate-CoA oxygenase
LFT47_RS17265	COG3460	Phenylacetate-CoA oxygenase
LFT47_RS17270	COG3396	Phenylacetate-CoA oxygenase
LFT47_RS17285	COG0745	RESPONSE REGULATOR receiver
LFT47_RS17310	COG2894	cell division
LFT47_RS17340	COG0574	Belongs to the PEP-utilizing enzyme family
LFT47_RS17340	COG3848	Pyruvate phosphate dikinase
LFT47_RS17355	COG1316	TRANSCRIPTIONal
LFT47_RS17380	COG5002	protein histidine kinase activity
LFT47_RS17390	COG0745	RESPONSE REGULATOR receiver
LFT47_RS17410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_RS17420	COG0747	negative chemotaxis
LFT47_RS17435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LFT47_RS17445	COG1116	anion transmembrane transporter activity
LFT47_RS17460	COG2050	protein possibly involved in aromatic compounds catabolism
LFT47_RS17485	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS17485	COG2030	dehydratase
LFT47_RS17495	COG1609	Transcriptional regulator
LFT47_RS17500	COG2182	Extracellular solute-binding protein
LFT47_RS17510	COG0395	ABC-type sugar transport system, permease component
LFT47_RS17520	COG0673	inositol 2-dehydrogenase activity
LFT47_RS17525	COG3415	Transposase
LFT47_RS17525	COG2801	Transposase and inactivated derivatives
LFT47_RS17530	COG1280	lysine exporter protein (LysE YggA)
LFT47_RS17535	COG2755	lipolytic protein G-D-S-L family
LFT47_RS17545	COG2801	Transposase and inactivated derivatives
LFT47_RS17545	COG3415	Transposase
LFT47_RS17555	COG1250	3-hydroxyacyl-CoA dehydrogenase
LFT47_RS17560	COG1024	Enoyl-CoA hydratase
LFT47_RS17565	COG0183	Belongs to the thiolase family
LFT47_RS17600	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LFT47_RS17625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LFT47_RS17635	COG0785	Cytochrome C biogenesis protein
LFT47_RS17645	COG0406	alpha-ribazole phosphatase activity
LFT47_RS17665	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LFT47_RS17690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LFT47_RS17695	COG1609	Transcriptional regulator
LFT47_RS17710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LFT47_RS17725	COG0640	Transcriptional regulator
LFT47_RS17730	COG0123	including yeast histone deacetylase and acetoin utilization protein
LFT47_RS17735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LFT47_RS17740	COG0569	domain protein
LFT47_RS17745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LFT47_RS17750	COG1082	Xylose isomerase domain protein TIM barrel
LFT47_RS17755	COG0248	Ppx GppA phosphatase
LFT47_RS17770	COG1754	DNA topoisomerase type I activity
LFT47_RS17770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LFT47_RS17780	COG2890	protein-(glutamine-N5) methyltransferase activity
LFT47_RS17795	COG1054	Belongs to the UPF0176 family
LFT47_RS17805	COG1111	helicase
LFT47_RS17805	COG1205	dead DEAH box helicase
LFT47_RS17875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LFT47_RS17885	COG1175	transmembrane transport
LFT47_RS17890	COG0395	ABC-type sugar transport system, permease component
LFT47_RS17900	COG1349	DNA-binding transcription factor activity
LFT47_RS17905	COG1609	Transcriptional regulator
LFT47_RS17915	COG1175	transmembrane transport
LFT47_RS17920	COG0395	ABC-type sugar transport system, permease component
LFT47_RS17935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LFT47_RS17965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LFT47_RS17970	COG1408	metallophosphoesterase
LFT47_RS17975	COG1132	(ABC) transporter
LFT47_RS17980	COG1132	(ABC) transporter
LFT47_RS18000	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LFT47_RS18005	COG0151	Belongs to the GarS family
LFT47_RS18025	COG1301	dicarboxylic acid transport
LFT47_RS18030	COG2066	Belongs to the glutaminase family
LFT47_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS18045	COG1953	Uracil, thiamine, allantoin
LFT47_RS18050	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LFT47_RS18065	COG3415	Transposase
LFT47_RS18065	COG2801	Transposase and inactivated derivatives
LFT47_RS18070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LFT47_RS18070	COG2080	2 iron, 2 sulfur cluster binding
LFT47_RS18080	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LFT47_RS18080	COG3608	succinylglutamate desuccinylase aspartoacylase
LFT47_RS18085	COG2252	PERMEase
LFT47_RS18090	COG0590	tRNA wobble adenosine to inosine editing
LFT47_RS18115	COG2233	PERMEase
LFT47_RS18125	COG1953	Uracil, thiamine, allantoin
LFT47_RS18130	COG1414	Transcriptional regulator
LFT47_RS18140	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LFT47_RS18150	COG3257	ureidoglycine aminohydrolase activity
LFT47_RS18155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LFT47_RS18160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LFT47_RS18175	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LFT47_RS18180	COG3387	PFAM Glycoside hydrolase 15-related
LFT47_RS18185	COG0563	adenylate kinase activity
LFT47_RS18190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LFT47_RS18200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LFT47_RS18220	COG2084	Dehydrogenase
LFT47_RS18225	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS18230	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_RS18240	COG1732	Glycine betaine
LFT47_RS18245	COG1174	glycine betaine transport
LFT47_RS18250	COG0517	IMP dehydrogenase activity
LFT47_RS18250	COG1125	glycine betaine transport
LFT47_RS18255	COG1174	glycine betaine transport
LFT47_RS18330	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS18355	COG2084	Dehydrogenase
LFT47_RS18360	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LFT47_RS18360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LFT47_RS18365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LFT47_RS18375	COG1609	Transcriptional regulator
LFT47_RS18385	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS18420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LFT47_RS18445	COG3958	Transketolase
LFT47_RS18450	COG3959	Transketolase, thiamine diphosphate binding domain
LFT47_RS18455	COG0477	Major facilitator Superfamily
LFT47_RS18460	COG1082	Xylose isomerase domain protein TIM barrel
LFT47_RS18465	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS18470	COG2376	Dihydroxyacetone kinase
LFT47_RS18475	COG0698	ribose 5-phosphate isomerase
LFT47_RS18485	COG1609	Transcriptional regulator
LFT47_RS18495	COG1175	transmembrane transport
LFT47_RS18500	COG0395	ABC-type sugar transport system, permease component
LFT47_RS18505	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
LFT47_RS18520	COG2971	BadF BadG BcrA BcrD
LFT47_RS18560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LFT47_RS18570	COG1733	regulation of RNA biosynthetic process
LFT47_RS18575	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LFT47_RS18600	COG2267	carboxylic ester hydrolase activity
LFT47_RS18615	COG3842	ATPase activity
LFT47_RS18630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LFT47_RS18635	COG1175	transmembrane transport
LFT47_RS18640	COG0395	ABC-type sugar transport system, permease component
LFT47_RS18645	COG1228	amidohydrolase
LFT47_RS18650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT47_RS18680	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LFT47_RS18685	COG2986	histidine ammonia-lyase
LFT47_RS18760	COG1136	(ABC) transporter
LFT47_RS18770	COG3622	Belongs to the hyi family
LFT47_RS18775	COG2084	Dehydrogenase
LFT47_RS18780	COG3960	tartronate-semialdehyde synthase activity
LFT47_RS18785	COG1929	Belongs to the glycerate kinase type-1 family
LFT47_RS18790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT47_RS18820	COG0765	amino acid transport
LFT47_RS18845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LFT47_RS18850	COG1126	abc transporter atp-binding protein
LFT47_RS18855	COG0765	amino acid transport
LFT47_RS18870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LFT47_RS18890	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_RS18895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LFT47_RS18905	COG2186	Transcriptional regulator
LFT47_RS18925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LFT47_RS18940	COG0640	Transcriptional regulator
LFT47_RS18955	COG0542	response to heat
LFT47_RS19000	COG0028	Belongs to the TPP enzyme family
LFT47_RS19005	COG3304	Inner membrane component domain
LFT47_RS19010	COG1793	dna ligase
LFT47_RS19030	COG0135	phosphoribosylanthranilate isomerase activity
LFT47_RS19050	COG0667	Aldo Keto reductase
LFT47_RS19090	COG1473	amidohydrolase
LFT47_RS19095	COG0477	Major facilitator Superfamily
LFT47_RS19100	COG2807	transmembrane transport
LFT47_RS19105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LFT47_RS19110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LFT47_RS19140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LFT47_RS19160	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_RS19185	COG1113	amino acid transport
LFT47_RS19190	COG0251	oxidation-reduction process
LFT47_RS19225	COG0789	Transcriptional regulator
LFT47_RS19230	COG0484	heat shock protein binding
LFT47_RS19235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LFT47_RS19240	COG0443	Heat shock 70 kDa protein
LFT47_RS19245	COG3739	integral membrane protein
LFT47_RS19265	COG2409	Drug exporters of the RND superfamily
LFT47_RS19285	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LFT47_RS19295	COG2226	methyltransferase
LFT47_RS19300	COG3795	YCII-related domain
LFT47_RS19305	COG4941	Belongs to the sigma-70 factor family
LFT47_RS19325	COG1280	lysine exporter protein (LysE YggA)
LFT47_RS19335	COG1609	Transcriptional regulator
LFT47_RS19340	COG1957	nucleoside hydrolase
LFT47_RS19345	COG0477	Major facilitator Superfamily
LFT47_RS19350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT47_RS19355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFT47_RS19365	COG1953	Uracil, thiamine, allantoin
LFT47_RS19390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LFT47_RS19450	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT47_RS19460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LFT47_RS19470	COG1122	ATPase activity
LFT47_RS19475	COG4721	ABC-type cobalt transport system, permease component
LFT47_RS19490	COG1320	monovalent cation:proton antiporter activity
LFT47_RS19495	COG2212	antiporter activity
LFT47_RS19505	COG0651	ATP synthesis coupled electron transport
LFT47_RS19510	COG1006	Multisubunit Na H antiporter MnhC subunit
LFT47_RS19515	COG2111	Na H antiporter
LFT47_RS19515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LFT47_RS19530	COG1472	Belongs to the glycosyl hydrolase 3 family
LFT47_RS19535	COG0363	glucosamine-6-phosphate deaminase activity
LFT47_RS19540	COG2985	domain, Protein
LFT47_RS19540	COG0490	domain, Protein
LFT47_RS19545	COG0475	glutathione-regulated potassium exporter activity
LFT47_RS19555	COG0717	Belongs to the dCTP deaminase family
LFT47_RS19585	COG0583	DNA-binding transcription factor activity
LFT47_RS19590	COG1309	transcriptional regulator
LFT47_RS19600	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LFT47_RS19610	COG3387	PFAM Glycoside hydrolase 15-related
LFT47_RS19615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_RS19625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT47_RS19630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT47_RS19650	COG3559	Exporter of polyketide antibiotics
LFT47_RS19660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_RS19665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_RS19670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_RS19680	COG1126	abc transporter atp-binding protein
LFT47_RS19685	COG0765	amino acid transport
LFT47_RS19700	COG2318	DinB family
LFT47_RS19710	COG0433	COG0433 Predicted ATPase
LFT47_RS19725	COG3336	cytochrome c oxidase
LFT47_RS19730	COG0776	regulation of translation
LFT47_RS19750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LFT47_RS19755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LFT47_RS19760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LFT47_RS19765	COG1017	nitric oxide dioxygenase activity
LFT47_RS19765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT47_RS19815	COG1120	ATPase activity
LFT47_RS19820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFT47_RS19825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFT47_RS19865	COG3012	SEC-C Motif Domain Protein
LFT47_RS19880	COG0667	Aldo Keto reductase
LFT47_RS19895	COG0438	transferase activity, transferring glycosyl groups
LFT47_RS19910	COG3177	Filamentation induced by cAMP protein fic
LFT47_RS19915	COG2186	Transcriptional regulator
LFT47_RS19925	COG1027	Aspartate ammonia-lyase
LFT47_RS19935	COG2186	Transcriptional regulator
LFT47_RS19950	COG3254	rhamnose metabolic process
LFT47_RS19960	COG0395	ABC-type sugar transport system, permease component
LFT47_RS19965	COG1175	transmembrane transport
LFT47_RS19975	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_RS19985	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS19990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LFT47_RS20030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LFT47_RS20040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LFT47_RS20055	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_RS20075	COG0477	Major facilitator Superfamily
LFT47_RS20095	COG1522	sequence-specific DNA binding
LFT47_RS20100	COG1280	lysine exporter protein (LysE YggA)
LFT47_RS20120	COG2197	response regulator
LFT47_RS20125	COG4585	Histidine kinase
LFT47_RS20130	COG0281	malic enzyme
LFT47_RS20135	COG1309	transcriptional regulator
LFT47_RS20145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LFT47_RS20150	COG0477	Major facilitator Superfamily
LFT47_RS20155	COG0477	Major facilitator Superfamily
LFT47_RS20160	COG2814	Major facilitator Superfamily
LFT47_RS20175	COG1113	amino acid transport
LFT47_RS20185	COG1846	Transcriptional regulator
LFT47_RS20190	COG0246	Mannitol dehydrogenase
LFT47_RS20195	COG2213	PTS system mannitol-specific
LFT47_RS20195	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT47_RS20205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LFT47_RS20210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT47_RS20215	COG1960	acyl-CoA dehydrogenase activity
LFT47_RS20220	COG1309	transcriptional regulator
LFT47_RS20235	COG2072	flavoprotein involved in K transport
LFT47_RS20250	COG0686	Belongs to the AlaDH PNT family
LFT47_RS20270	COG0673	inositol 2-dehydrogenase activity
LFT47_RS20275	COG1309	transcriptional regulator
LFT47_RS20280	COG0431	NADPH-dependent FMN reductase
LFT47_RS20300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LFT47_RS20320	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_RS20325	COG0022	dehydrogenase e1 component
LFT47_RS20335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LFT47_RS20340	COG1950	PFAM Membrane protein of
LFT47_RS20355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LFT47_RS20375	COG1607	acyl-coa hydrolase
LFT47_RS20380	COG4221	oxidoreductase activity
LFT47_RS20385	COG0477	Major facilitator Superfamily
LFT47_RS20390	COG1984	allophanate hydrolase subunit 2
LFT47_RS20395	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_RS20400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_RS20405	COG0583	DNA-binding transcription factor activity
LFT47_RS20415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LFT47_RS20420	COG0436	Aminotransferase
LFT47_RS20440	COG3971	2-oxopent-4-enoate hydratase activity
LFT47_RS20455	COG1802	Transcriptional regulator
LFT47_RS20470	COG0596	Alpha beta hydrolase
LFT47_RS20515	COG4221	oxidoreductase activity
LFT47_RS20530	COG1132	(ABC) transporter
LFT47_RS20545	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LFT47_RS20550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LFT47_RS20555	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LFT47_RS20595	COG1850	ribulose-bisphosphate carboxylase activity
LFT47_RS20600	COG2186	Transcriptional regulator
LFT47_RS20610	COG1653	transport
LFT47_RS20615	COG1175	transmembrane transport
LFT47_RS20625	COG0673	inositol 2-dehydrogenase activity
LFT47_RS20645	COG1940	carbohydrate kinase activity
LFT47_RS20655	COG1070	Carbohydrate kinase
LFT47_RS20660	COG2115	Belongs to the xylose isomerase family
LFT47_RS20665	COG0277	FAD linked oxidase domain protein
LFT47_RS20670	COG1940	carbohydrate kinase activity
LFT47_RS20675	COG2017	converts alpha-aldose to the beta-anomer
LFT47_RS20710	COG1970	mechanosensitive ion channel activity
LFT47_RS20725	COG0506	proline dehydrogenase activity
LFT47_RS20730	COG2271	Major facilitator Superfamily
LFT47_RS20755	COG1278	Cold shock
LFT47_RS20795	COG0251	oxidation-reduction process
LFT47_RS20805	COG0765	amino acid transport
LFT47_RS20825	COG2161	toxin-antitoxin pair type II binding
LFT47_RS20860	COG1414	Transcriptional regulator
LFT47_RS20865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LFT47_RS20875	COG0183	Belongs to the thiolase family
LFT47_RS20880	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LFT47_RS20890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LFT47_RS20900	COG3485	protocatechuate 3,4-dioxygenase
LFT47_RS20905	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LFT47_RS20905	COG1082	Xylose isomerase domain protein TIM barrel
LFT47_RS20910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFT47_RS20915	COG1414	Transcriptional regulator
LFT47_RS20920	COG0477	Major facilitator Superfamily
LFT47_RS20930	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LFT47_RS20945	COG2610	gluconate transmembrane transporter activity
LFT47_RS20955	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LFT47_RS20970	COG1414	Transcriptional regulator
LFT47_RS20980	COG5001	Diguanylate cyclase
LFT47_RS20980	COG4251	negative regulation of phosphorylation
LFT47_RS20980	COG3706	GGDEF domain
LFT47_RS20980	COG2203	Gaf domain
LFT47_RS20990	COG1414	Transcriptional regulator
LFT47_RS20995	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LFT47_RS21000	COG0395	ABC-type sugar transport system, permease component
LFT47_RS21010	COG1653	transport
LFT47_RS21015	COG1937	Protein conserved in bacteria
LFT47_RS21055	COG0534	Mate efflux family protein
LFT47_RS21070	COG1607	acyl-coa hydrolase
LFT47_RS21080	COG0305	Participates in initiation and elongation during chromosome replication
LFT47_RS21105	COG0359	binds to the 23S rRNA
LFT47_RS21110	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LFT47_RS21120	COG0360	Binds together with S18 to 16S ribosomal RNA
LFT47_RS21125	COG1742	UPF0060 membrane protein
LFT47_RS21135	COG1362	aminopeptidase activity
LFT47_RS21145	COG2197	response regulator
LFT47_RS21150	COG4585	Histidine kinase
LFT47_RS21160	COG1131	(ABC) transporter
LFT47_RS21175	COG1136	(ABC) transporter
LFT47_RS21180	COG0577	efflux transmembrane transporter activity
LFT47_RS21180	COG1136	(ABC) transporter
LFT47_RS21190	COG0738	Major facilitator superfamily
LFT47_RS21200	COG0488	(ABC) transporter
LFT47_RS21205	COG1309	transcriptional regulator
LFT47_RS21215	COG0768	penicillin binding
LFT47_RS21220	COG2197	response regulator
LFT47_RS21225	COG4585	Histidine kinase
LFT47_RS21235	COG1136	(ABC) transporter
LFT47_RS21240	COG3415	Transposase
LFT47_RS21240	COG2801	Transposase and inactivated derivatives
LFT47_RS21245	COG1733	regulation of RNA biosynthetic process
LFT47_RS21250	COG2910	NAD(P)H-binding
LFT47_RS21270	COG0406	alpha-ribazole phosphatase activity
LFT47_RS21275	COG0617	tRNA 3'-terminal CCA addition
LFT47_RS21295	COG0492	ferredoxin-NADP+ reductase activity
LFT47_RS21300	COG3118	belongs to the thioredoxin family
LFT47_RS21310	COG1192	Involved in chromosome partitioning
LFT47_RS21315	COG0357	Ribosomal RNA small subunit methyltransferase G
LFT47_RS21325	COG0706	membrane insertase activity
LFT47_RS21330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LFT47_RS21335	COG0594	ribonuclease P activity
LFT47_RS21340	COG0230	Belongs to the bacterial ribosomal protein bL34 family