locus-tag	class	description
LDN90_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LDN90_RS00010	COG0592	DNA-directed DNA polymerase activity
LDN90_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDN90_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LDN90_RS00030	COG0187	DNA topoisomerase II activity
LDN90_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LDN90_RS00040	COG3266	domain, Protein
LDN90_RS00070	COG1215	transferase activity, transferring glycosyl groups
LDN90_RS00085	COG0705	Rhomboid family
LDN90_RS00085	COG0457	Tetratricopeptide repeat
LDN90_RS00095	COG2818	Glycosylase
LDN90_RS00105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LDN90_RS00110	COG1595	DNA-templated transcription, initiation
LDN90_RS00125	COG3764	Sortase (surface protein transpeptidase)
LDN90_RS00135	COG0515	serine threonine protein kinase
LDN90_RS00140	COG0515	serine threonine protein kinase
LDN90_RS00145	COG0768	penicillin binding
LDN90_RS00160	COG1716	ATPase activity
LDN90_RS00165	COG1716	ATPase activity
LDN90_RS00175	COG1609	Transcriptional regulator
LDN90_RS00200	COG0346	lactoylglutathione lyase activity
LDN90_RS00215	COG2186	Transcriptional regulator
LDN90_RS00220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LDN90_RS00225	COG0477	Major facilitator Superfamily
LDN90_RS00230	COG1984	allophanate hydrolase subunit 2
LDN90_RS00235	COG4770	biotin carboxylase activity
LDN90_RS00240	COG0277	FAD linked oxidase domain protein
LDN90_RS00245	COG0385	Bile acid
LDN90_RS00250	COG0659	secondary active sulfate transmembrane transporter activity
LDN90_RS00275	COG0561	phosphatase activity
LDN90_RS00290	COG0584	glycerophosphoryl diester phosphodiesterase
LDN90_RS00295	COG3250	beta-galactosidase activity
LDN90_RS00300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDN90_RS00305	COG1929	Belongs to the glycerate kinase type-1 family
LDN90_RS00325	COG1082	Xylose isomerase domain protein TIM barrel
LDN90_RS00330	COG2271	Major facilitator Superfamily
LDN90_RS00335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LDN90_RS00340	COG0693	protein deglycase activity
LDN90_RS00350	COG3655	Transcriptional regulator
LDN90_RS00355	COG2233	PERMEase
LDN90_RS00360	COG0778	Nitroreductase
LDN90_RS00380	COG3104	oligopeptide transport
LDN90_RS00390	COG3340	Belongs to the peptidase S51 family
LDN90_RS00395	COG0425	Belongs to the sulfur carrier protein TusA family
LDN90_RS00395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDN90_RS00410	COG1597	lipid kinase activity
LDN90_RS00415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LDN90_RS00425	COG0561	phosphatase activity
LDN90_RS00440	COG1191	sigma factor activity
LDN90_RS00450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LDN90_RS00455	COG0859	PFAM glycosyl transferase family 9
LDN90_RS00465	COG0438	transferase activity, transferring glycosyl groups
LDN90_RS00470	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LDN90_RS00475	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LDN90_RS00475	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LDN90_RS00490	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LDN90_RS00490	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LDN90_RS00560	COG0037	tRNA processing
LDN90_RS00570	COG1609	Transcriptional regulator
LDN90_RS00575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LDN90_RS00580	COG0302	gtp cyclohydrolase
LDN90_RS00590	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LDN90_RS00620	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LDN90_RS00625	COG2814	Major facilitator Superfamily
LDN90_RS00680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LDN90_RS00705	COG0823	Involved in the tonB-independent uptake of proteins
LDN90_RS00705	COG1506	peptidase
LDN90_RS00710	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LDN90_RS00725	COG2376	Dihydroxyacetone kinase
LDN90_RS00730	COG1461	Dihydroxyacetone kinase
LDN90_RS00735	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LDN90_RS00740	COG3237	CsbD-like
LDN90_RS00780	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LDN90_RS00790	COG0671	phosphoesterase, PA-phosphatase related
LDN90_RS00800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LDN90_RS00815	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDN90_RS00870	COG1609	Transcriptional regulator
LDN90_RS00885	COG0436	Aminotransferase
LDN90_RS00890	COG0586	Pfam SNARE associated Golgi protein
LDN90_RS00895	COG0831	urea catabolic process
LDN90_RS00900	COG0832	Belongs to the urease beta subunit family
LDN90_RS00905	COG0804	urea catabolic process
LDN90_RS00910	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LDN90_RS00915	COG0830	nickel cation binding
LDN90_RS00920	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LDN90_RS00925	COG0829	nickel cation binding
LDN90_RS00930	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LDN90_RS00965	COG0656	L-ascorbic acid biosynthetic process
LDN90_RS00975	COG0667	Aldo Keto reductase
LDN90_RS00980	COG0656	L-ascorbic acid biosynthetic process
LDN90_RS00990	COG3360	Dodecin
LDN90_RS00995	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS01005	COG2186	Transcriptional regulator
LDN90_RS01010	COG2267	carboxylic ester hydrolase activity
LDN90_RS01020	COG2084	Dehydrogenase
LDN90_RS01025	COG2610	gluconate transmembrane transporter activity
LDN90_RS01080	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LDN90_RS01085	COG0076	glutamate decarboxylase activity
LDN90_RS01120	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS01140	COG0346	lactoylglutathione lyase activity
LDN90_RS01150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDN90_RS01155	COG0477	Major facilitator Superfamily
LDN90_RS01165	COG2890	protein-(glutamine-N5) methyltransferase activity
LDN90_RS01180	COG3285	dna ligase
LDN90_RS01180	COG1793	dna ligase
LDN90_RS01185	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LDN90_RS01190	COG0395	ABC-type sugar transport system, permease component
LDN90_RS01195	COG1175	transmembrane transport
LDN90_RS01210	COG2188	Transcriptional regulator
LDN90_RS01260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDN90_RS01265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDN90_RS01265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDN90_RS01265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDN90_RS01270	COG1105	Belongs to the carbohydrate kinase PfkB family
LDN90_RS01275	COG1349	DNA-binding transcription factor activity
LDN90_RS01295	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LDN90_RS01320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDN90_RS01345	COG1846	Transcriptional regulator
LDN90_RS01370	COG0142	geranyltranstransferase activity
LDN90_RS01375	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LDN90_RS01395	COG0583	DNA-binding transcription factor activity
LDN90_RS01425	COG2186	Transcriptional regulator
LDN90_RS01440	COG0129	dihydroxy-acid dehydratase activity
LDN90_RS01445	COG0028	Belongs to the TPP enzyme family
LDN90_RS01470	COG1802	Transcriptional regulator
LDN90_RS01480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LDN90_RS01490	COG1126	abc transporter atp-binding protein
LDN90_RS01495	COG0765	amino acid transport
LDN90_RS01500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN90_RS01510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDN90_RS01515	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS01520	COG0473	3-isopropylmalate dehydrogenase activity
LDN90_RS01550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN90_RS01555	COG4172	Belongs to the ABC transporter superfamily
LDN90_RS01560	COG0583	DNA-binding transcription factor activity
LDN90_RS01575	COG0673	inositol 2-dehydrogenase activity
LDN90_RS01600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LDN90_RS01605	COG1984	allophanate hydrolase subunit 2
LDN90_RS01610	COG2733	membrane
LDN90_RS01645	COG4122	O-methyltransferase activity
LDN90_RS01650	COG0454	-acetyltransferase
LDN90_RS01650	COG0456	acetyltransferase
LDN90_RS01665	COG0583	DNA-binding transcription factor activity
LDN90_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS01685	COG1131	(ABC) transporter
LDN90_RS01690	COG3559	Exporter of polyketide antibiotics
LDN90_RS01700	COG1733	regulation of RNA biosynthetic process
LDN90_RS01720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LDN90_RS01740	COG2902	Dehydrogenase
LDN90_RS01755	COG2252	PERMEase
LDN90_RS01780	COG0574	Belongs to the PEP-utilizing enzyme family
LDN90_RS01780	COG3848	Pyruvate phosphate dikinase
LDN90_RS01810	COG3655	Transcriptional regulator
LDN90_RS01840	COG3559	Exporter of polyketide antibiotics
LDN90_RS01845	COG1131	(ABC) transporter
LDN90_RS01855	COG0395	ABC-type sugar transport system, permease component
LDN90_RS01860	COG1175	transmembrane transport
LDN90_RS01865	COG1285	pathogenesis
LDN90_RS01890	COG1302	Protein conserved in bacteria
LDN90_RS01930	COG1653	transport
LDN90_RS01935	COG1175	transmembrane transport
LDN90_RS01940	COG0395	ABC-type sugar transport system, permease component
LDN90_RS01945	COG1609	Transcriptional regulator
LDN90_RS01965	COG2197	response regulator
LDN90_RS01970	COG4585	Histidine kinase
LDN90_RS01985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDN90_RS01990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LDN90_RS01995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LDN90_RS02025	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS02030	COG0395	ABC-type sugar transport system, permease component
LDN90_RS02035	COG1175	transmembrane transport
LDN90_RS02045	COG3684	Belongs to the aldolase LacD family
LDN90_RS02055	COG0673	inositol 2-dehydrogenase activity
LDN90_RS02060	COG1349	DNA-binding transcription factor activity
LDN90_RS02095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LDN90_RS02105	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDN90_RS02110	COG0303	'Molybdopterin
LDN90_RS02115	COG1063	alcohol dehydrogenase
LDN90_RS02130	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LDN90_RS02135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDN90_RS02140	COG3404	Formiminotransferase-cyclodeaminase
LDN90_RS02155	COG1802	Transcriptional regulator
LDN90_RS02160	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LDN90_RS02175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDN90_RS02180	COG2197	response regulator
LDN90_RS02205	COG0415	Belongs to the DNA photolyase family
LDN90_RS02235	COG1024	Enoyl-CoA hydratase
LDN90_RS02255	COG1131	(ABC) transporter
LDN90_RS02285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDN90_RS02290	COG1960	acyl-CoA dehydrogenase activity
LDN90_RS02305	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS02330	COG0789	Transcriptional regulator
LDN90_RS02335	COG1695	Transcriptional regulator
LDN90_RS02345	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS02350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LDN90_RS02360	COG0531	amino acid
LDN90_RS02365	COG2186	Transcriptional regulator
LDN90_RS02375	COG1609	Transcriptional regulator
LDN90_RS02390	COG0395	ABC-type sugar transport system, permease component
LDN90_RS02400	COG0673	inositol 2-dehydrogenase activity
LDN90_RS02410	COG1904	glucuronate isomerase
LDN90_RS02415	COG0246	Mannitol dehydrogenase
LDN90_RS02420	COG4948	Mandelate Racemase Muconate Lactonizing
LDN90_RS02425	COG3265	gluconokinase activity
LDN90_RS02430	COG4213	ABC transporter substrate-binding protein
LDN90_RS02435	COG1129	ABC transporter
LDN90_RS02440	COG4214	carbohydrate transport
LDN90_RS02445	COG1609	Transcriptional regulator
LDN90_RS02450	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LDN90_RS02475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDN90_RS02475	COG0357	Ribosomal RNA small subunit methyltransferase G
LDN90_RS02525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LDN90_RS02530	COG0477	Major facilitator Superfamily
LDN90_RS02550	COG3321	synthase
LDN90_RS02550	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS02550	COG0604	alcohol dehydrogenase
LDN90_RS02555	COG0488	(ABC) transporter
LDN90_RS02565	COG1309	transcriptional regulator
LDN90_RS02575	COG2814	Major facilitator Superfamily
LDN90_RS02580	COG2186	Transcriptional regulator
LDN90_RS02600	COG0765	amino acid transport
LDN90_RS02605	COG1126	abc transporter atp-binding protein
LDN90_RS02625	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS02635	COG0477	Major facilitator Superfamily
LDN90_RS02675	COG2197	response regulator
LDN90_RS02710	COG0765	amino acid transport
LDN90_RS02715	COG1126	abc transporter atp-binding protein
LDN90_RS02720	COG0673	inositol 2-dehydrogenase activity
LDN90_RS02740	COG1621	beta-fructofuranosidase activity
LDN90_RS02750	COG0395	ABC-type sugar transport system, permease component
LDN90_RS02755	COG4209	transmembrane transport
LDN90_RS02760	COG1609	Transcriptional regulator
LDN90_RS02775	COG1832	CoA-binding protein
LDN90_RS02790	COG2315	Protein conserved in bacteria
LDN90_RS02800	COG1653	transport
LDN90_RS02805	COG1175	transmembrane transport
LDN90_RS02810	COG0395	ABC-type sugar transport system, permease component
LDN90_RS02885	COG3706	GGDEF domain
LDN90_RS02905	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LDN90_RS02910	COG0047	phosphoribosylformylglycinamidine synthase activity
LDN90_RS02965	COG0024	Methionine aminopeptidase
LDN90_RS02970	COG1846	Transcriptional regulator
LDN90_RS02985	COG5416	Lipopolysaccharide assembly protein A domain
LDN90_RS03015	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS03045	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LDN90_RS03060	COG1876	peptidase activity
LDN90_RS03065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDN90_RS03065	COG3323	Protein of unknown function (DUF1653)
LDN90_RS03080	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS03100	COG0739	heme binding
LDN90_RS03100	COG0741	lytic transglycosylase activity
LDN90_RS03100	COG1196	nuclear chromosome segregation
LDN90_RS03105	COG0386	Belongs to the glutathione peroxidase family
LDN90_RS03110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LDN90_RS03135	COG1309	transcriptional regulator
LDN90_RS03140	COG2271	Major facilitator Superfamily
LDN90_RS03145	COG0494	nUDIX hydrolase
LDN90_RS03150	COG1309	transcriptional regulator
LDN90_RS03170	COG1609	Transcriptional regulator
LDN90_RS03180	COG1175	transmembrane transport
LDN90_RS03185	COG0395	ABC-type sugar transport system, permease component
LDN90_RS03200	COG0438	transferase activity, transferring glycosyl groups
LDN90_RS03215	COG0589	response to stress
LDN90_RS03235	COG3290	protein histidine kinase activity
LDN90_RS03240	COG4565	transcriptional regulatory protein
LDN90_RS03250	COG4702	Belongs to the UPF0303 family
LDN90_RS03260	COG0823	Involved in the tonB-independent uptake of proteins
LDN90_RS03270	COG0673	inositol 2-dehydrogenase activity
LDN90_RS03275	COG0673	inositol 2-dehydrogenase activity
LDN90_RS03285	COG0395	ABC-type sugar transport system, permease component
LDN90_RS03295	COG2182	Extracellular solute-binding protein
LDN90_RS03300	COG0673	inositol 2-dehydrogenase activity
LDN90_RS03310	COG1940	carbohydrate kinase activity
LDN90_RS03310	COG1846	Transcriptional regulator
LDN90_RS03315	COG2807	transmembrane transport
LDN90_RS03320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LDN90_RS03330	COG1476	TRANSCRIPTIONal
LDN90_RS03340	COG1309	transcriptional regulator
LDN90_RS03350	COG0351	phosphomethylpyrimidine kinase
LDN90_RS03360	COG2205	protein histidine kinase activity
LDN90_RS03365	COG0745	RESPONSE REGULATOR receiver
LDN90_RS03370	COG0477	Major facilitator Superfamily
LDN90_RS03385	COG0343	queuine tRNA-ribosyltransferase activity
LDN90_RS03415	COG3842	ATPase activity
LDN90_RS03465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LDN90_RS03490	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LDN90_RS03500	COG0586	Pfam SNARE associated Golgi protein
LDN90_RS03515	COG0564	pseudouridine synthase activity
LDN90_RS03545	COG2364	Membrane
LDN90_RS03550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDN90_RS03555	COG1201	RNA secondary structure unwinding
LDN90_RS03610	COG0438	transferase activity, transferring glycosyl groups
LDN90_RS03625	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LDN90_RS03645	COG0789	Transcriptional regulator
LDN90_RS03655	COG2205	protein histidine kinase activity
LDN90_RS03660	COG0745	RESPONSE REGULATOR receiver
LDN90_RS03670	COG2062	phosphohistidine phosphatase, SixA
LDN90_RS03680	COG0730	response to heat
LDN90_RS03685	COG0402	S-adenosylhomocysteine deaminase activity
LDN90_RS03690	COG2814	Major facilitator Superfamily
LDN90_RS03705	COG0583	DNA-binding transcription factor activity
LDN90_RS03710	COG0697	spore germination
LDN90_RS03720	COG1309	transcriptional regulator
LDN90_RS03725	COG1511	domain protein
LDN90_RS03740	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LDN90_RS03745	COG1940	carbohydrate kinase activity
LDN90_RS03755	COG4608	Belongs to the ABC transporter superfamily
LDN90_RS03760	COG0444	Belongs to the ABC transporter superfamily
LDN90_RS03770	COG0747	negative chemotaxis
LDN90_RS03775	COG2188	Transcriptional regulator
LDN90_RS03785	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LDN90_RS03810	COG0514	ATP-dependent DNA helicase (RecQ)
LDN90_RS03815	COG0477	Major facilitator Superfamily
LDN90_RS03825	COG1505	serine-type exopeptidase activity
LDN90_RS03835	COG1113	amino acid transport
LDN90_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS03855	COG3321	synthase
LDN90_RS03855	COG0604	alcohol dehydrogenase
LDN90_RS03865	COG1966	Carbon starvation protein
LDN90_RS03885	COG0656	L-ascorbic acid biosynthetic process
LDN90_RS03915	COG0492	ferredoxin-NADP+ reductase activity
LDN90_RS03940	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LDN90_RS03945	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LDN90_RS03965	COG0588	phosphoglycerate mutase activity
LDN90_RS03995	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LDN90_RS04000	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LDN90_RS04010	COG0215	cysteine-tRNA ligase activity
LDN90_RS04045	COG0366	Alpha amylase catalytic
LDN90_RS04055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LDN90_RS04090	COG1609	Transcriptional regulator
LDN90_RS04095	COG0366	Alpha amylase catalytic
LDN90_RS04110	COG3833	ABC-type maltose transport systems, permease component
LDN90_RS04115	COG0366	Alpha amylase catalytic
LDN90_RS04120	COG0277	FAD linked oxidase domain protein
LDN90_RS04135	COG0402	S-adenosylhomocysteine deaminase activity
LDN90_RS04140	COG4608	Belongs to the ABC transporter superfamily
LDN90_RS04145	COG0444	Belongs to the ABC transporter superfamily
LDN90_RS04150	COG0601	transmembrane transport
LDN90_RS04160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN90_RS04165	COG0402	S-adenosylhomocysteine deaminase activity
LDN90_RS04185	COG3842	ATPase activity
LDN90_RS04220	COG3118	belongs to the thioredoxin family
LDN90_RS04230	COG0475	glutathione-regulated potassium exporter activity
LDN90_RS04240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LDN90_RS04245	COG0588	phosphoglycerate mutase activity
LDN90_RS04250	COG1252	NADH dehydrogenase
LDN90_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS04290	COG1960	acyl-CoA dehydrogenase activity
LDN90_RS04315	COG0579	oxidoreductase
LDN90_RS04345	COG2957	Belongs to the agmatine deiminase family
LDN90_RS04380	COG0477	Major facilitator Superfamily
LDN90_RS04390	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDN90_RS04390	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDN90_RS04395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDN90_RS04400	COG0509	glycine decarboxylation via glycine cleavage system
LDN90_RS04405	COG1760	l-serine dehydratase
LDN90_RS04410	COG1864	DNA RNA non-specific endonuclease
LDN90_RS04410	COG3591	Belongs to the peptidase S1B family
LDN90_RS04430	COG0577	efflux transmembrane transporter activity
LDN90_RS04430	COG1136	(ABC) transporter
LDN90_RS04455	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LDN90_RS04475	COG0459	protein refolding
LDN90_RS04480	COG0328	RNA-DNA hybrid ribonuclease activity
LDN90_RS04490	COG2205	protein histidine kinase activity
LDN90_RS04495	COG0745	RESPONSE REGULATOR receiver
LDN90_RS04505	COG0583	DNA-binding transcription factor activity
LDN90_RS04515	COG2132	Multicopper oxidase
LDN90_RS04540	COG1278	Cold shock
LDN90_RS04560	COG0739	heme binding
LDN90_RS04565	COG0791	NLP P60 protein
LDN90_RS04565	COG3103	Sh3 type 3 domain protein
LDN90_RS04565	COG1388	LysM domain
LDN90_RS04580	COG0746	molybdenum cofactor guanylyltransferase activity
LDN90_RS04595	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDN90_RS04605	COG1126	abc transporter atp-binding protein
LDN90_RS04610	COG0765	amino acid transport
LDN90_RS04615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN90_RS04630	COG0488	(ABC) transporter
LDN90_RS04635	COG1132	(ABC) transporter
LDN90_RS04640	COG0494	nUDIX hydrolase
LDN90_RS04670	COG0483	inositol monophosphate 1-phosphatase activity
LDN90_RS04685	COG0045	succinate-CoA ligase (ADP-forming) activity
LDN90_RS04695	COG1942	4-Oxalocrotonate Tautomerase
LDN90_RS04700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDN90_RS04710	COG3962	Belongs to the TPP enzyme family
LDN90_RS04725	COG0673	inositol 2-dehydrogenase activity
LDN90_RS04730	COG1082	Xylose isomerase domain protein TIM barrel
LDN90_RS04735	COG3718	enzyme involved in inositol metabolism
LDN90_RS04740	COG2188	Transcriptional regulator
LDN90_RS04750	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDN90_RS04765	COG0673	inositol 2-dehydrogenase activity
LDN90_RS04775	COG0673	inositol 2-dehydrogenase activity
LDN90_RS04785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDN90_RS04785	COG0519	Catalyzes the synthesis of GMP from XMP
LDN90_RS04825	COG1396	sequence-specific DNA binding
LDN90_RS04845	COG0028	Belongs to the TPP enzyme family
LDN90_RS04875	COG3142	Participates in the control of copper homeostasis
LDN90_RS04880	COG1621	beta-fructofuranosidase activity
LDN90_RS04895	COG1653	transport
LDN90_RS04905	COG0395	ABC-type sugar transport system, permease component
LDN90_RS04915	COG1609	Transcriptional regulator
LDN90_RS04920	COG1621	beta-fructofuranosidase activity
LDN90_RS04940	COG0741	lytic transglycosylase activity
LDN90_RS04940	COG0739	heme binding
LDN90_RS04940	COG1196	nuclear chromosome segregation
LDN90_RS04945	COG1401	restriction endodeoxyribonuclease activity
LDN90_RS04960	COG5002	protein histidine kinase activity
LDN90_RS04965	COG0745	RESPONSE REGULATOR receiver
LDN90_RS04970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LDN90_RS04985	COG0604	alcohol dehydrogenase
LDN90_RS04995	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS05000	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS05010	COG1024	Enoyl-CoA hydratase
LDN90_RS05015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDN90_RS05025	COG0477	Major facilitator Superfamily
LDN90_RS05030	COG1396	sequence-specific DNA binding
LDN90_RS05045	COG2124	cytochrome p450
LDN90_RS05050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LDN90_RS05060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDN90_RS05070	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LDN90_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS05100	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LDN90_RS05105	COG1902	pentaerythritol trinitrate reductase activity
LDN90_RS05120	COG2376	Dihydroxyacetone kinase
LDN90_RS05125	COG0698	ribose 5-phosphate isomerase
LDN90_RS05130	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN90_RS05165	COG2183	response to ionizing radiation
LDN90_RS05180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LDN90_RS05190	COG1254	Belongs to the acylphosphatase family
LDN90_RS05195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDN90_RS05200	COG2186	Transcriptional regulator
LDN90_RS05205	COG0477	Major facilitator Superfamily
LDN90_RS05215	COG0640	Transcriptional regulator
LDN90_RS05220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDN90_RS05230	COG4209	transmembrane transport
LDN90_RS05235	COG0395	ABC-type sugar transport system, permease component
LDN90_RS05275	COG1472	Belongs to the glycosyl hydrolase 3 family
LDN90_RS05280	COG0673	inositol 2-dehydrogenase activity
LDN90_RS05295	COG1609	Transcriptional regulator
LDN90_RS05310	COG0477	Major facilitator Superfamily
LDN90_RS05320	COG1937	Protein conserved in bacteria
LDN90_RS05330	COG0730	response to heat
LDN90_RS05340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDN90_RS05345	COG0640	Transcriptional regulator
LDN90_RS05360	COG3973	AAA domain
LDN90_RS05365	COG0604	alcohol dehydrogenase
LDN90_RS05365	COG3321	synthase
LDN90_RS05375	COG1309	transcriptional regulator
LDN90_RS05390	COG2217	Heavy metal translocating P-type atpase
LDN90_RS05415	COG1131	(ABC) transporter
LDN90_RS05425	COG0640	Transcriptional regulator
LDN90_RS05510	COG1401	restriction endodeoxyribonuclease activity
LDN90_RS05580	COG2072	flavoprotein involved in K transport
LDN90_RS05590	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS05605	COG1278	Cold shock
LDN90_RS05625	COG1846	Transcriptional regulator
LDN90_RS05655	COG2755	lipolytic protein G-D-S-L family
LDN90_RS05660	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LDN90_RS05665	COG0438	transferase activity, transferring glycosyl groups
LDN90_RS05665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LDN90_RS05685	COG0789	Transcriptional regulator
LDN90_RS05690	COG0071	Belongs to the small heat shock protein (HSP20) family
LDN90_RS05695	COG0484	heat shock protein binding
LDN90_RS05710	COG2268	Band 7 protein
LDN90_RS05740	COG0477	Major facilitator Superfamily
LDN90_RS05745	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LDN90_RS05755	COG0138	bifunctional purine biosynthesis protein purh
LDN90_RS05765	COG2838	Isocitrate dehydrogenase
LDN90_RS05780	COG0673	inositol 2-dehydrogenase activity
LDN90_RS05795	COG0577	efflux transmembrane transporter activity
LDN90_RS05795	COG1136	(ABC) transporter
LDN90_RS05800	COG0577	efflux transmembrane transporter activity
LDN90_RS05800	COG1136	(ABC) transporter
LDN90_RS05805	COG1136	(ABC) transporter
LDN90_RS05820	COG4213	ABC transporter substrate-binding protein
LDN90_RS05830	COG1129	ABC transporter
LDN90_RS05840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDN90_RS05850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDN90_RS05855	COG0531	amino acid
LDN90_RS05885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDN90_RS05895	COG2197	response regulator
LDN90_RS05905	COG1131	(ABC) transporter
LDN90_RS05925	COG0708	Exodeoxyribonuclease III
LDN90_RS05930	COG0180	Tryptophanyl-tRNA synthetase
LDN90_RS05970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LDN90_RS05985	COG2009	succinate dehydrogenase
LDN90_RS05995	COG1473	amidohydrolase
LDN90_RS05995	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LDN90_RS06000	COG1846	Transcriptional regulator
LDN90_RS06005	COG1764	response to oxidative stress
LDN90_RS06010	COG2130	NADP-dependent
LDN90_RS06015	COG1744	ABC transporter substrate-binding protein PnrA-like
LDN90_RS06020	COG3845	ABC transporter
LDN90_RS06025	COG4603	Belongs to the binding-protein-dependent transport system permease family
LDN90_RS06030	COG1079	Belongs to the binding-protein-dependent transport system permease family
LDN90_RS06050	COG0586	Pfam SNARE associated Golgi protein
LDN90_RS06055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LDN90_RS06065	COG0148	phosphopyruvate hydratase activity
LDN90_RS06090	COG1252	NADH dehydrogenase
LDN90_RS06135	COG0183	Belongs to the thiolase family
LDN90_RS06140	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LDN90_RS06150	COG2017	converts alpha-aldose to the beta-anomer
LDN90_RS06160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LDN90_RS06170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDN90_RS06180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LDN90_RS06205	COG0604	alcohol dehydrogenase
LDN90_RS06215	COG2271	Major facilitator Superfamily
LDN90_RS06235	COG1228	amidohydrolase
LDN90_RS06240	COG1331	Highly conserved protein containing a thioredoxin domain
LDN90_RS06250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LDN90_RS06255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LDN90_RS06285	COG0114	fumarate hydratase activity
LDN90_RS06300	COG1494	fructose-1,6-bisphosphatase
LDN90_RS06370	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LDN90_RS06375	COG1376	ErfK ybiS ycfS ynhG family protein
LDN90_RS06380	COG1357	PFAM Pentapeptide repeats (8 copies)
LDN90_RS06430	COG0714	Associated with various cellular activities
LDN90_RS06435	COG0084	hydrolase, TatD family'
LDN90_RS06445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LDN90_RS06450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LDN90_RS06455	COG0488	(ABC) transporter
LDN90_RS06470	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LDN90_RS06480	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LDN90_RS06485	COG0193	aminoacyl-tRNA hydrolase activity
LDN90_RS06510	COG0822	iron-sulfur transferase activity
LDN90_RS06515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LDN90_RS06530	COG0702	epimerase
LDN90_RS06540	COG1988	membrane-bound metal-dependent
LDN90_RS06550	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LDN90_RS06615	COG2814	Major facilitator Superfamily
LDN90_RS06630	COG0583	DNA-binding transcription factor activity
LDN90_RS06640	COG3395	kinase activity
LDN90_RS06645	COG0235	Class ii aldolase
LDN90_RS06660	COG2146	nitrite reductase [NAD(P)H] activity
LDN90_RS06660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDN90_RS06670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDN90_RS06675	COG1621	beta-fructofuranosidase activity
LDN90_RS06715	COG0243	molybdopterin cofactor binding
LDN90_RS06720	COG2223	nitrite transmembrane transporter activity
LDN90_RS06725	COG0477	Major facilitator Superfamily
LDN90_RS06730	COG4770	biotin carboxylase activity
LDN90_RS06735	COG0424	maF-like protein
LDN90_RS06740	COG2409	Drug exporters of the RND superfamily
LDN90_RS06750	COG0393	Putative heavy-metal-binding
LDN90_RS06755	COG1823	symporter activity
LDN90_RS06770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LDN90_RS06775	COG0300	oxidoreductase activity
LDN90_RS06780	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LDN90_RS06780	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LDN90_RS06805	COG0714	Associated with various cellular activities
LDN90_RS06825	COG0631	protein serine/threonine phosphatase activity
LDN90_RS06845	COG1674	ftsk spoiiie
LDN90_RS06850	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LDN90_RS06855	COG0483	inositol monophosphate 1-phosphatase activity
LDN90_RS06865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN90_RS06875	COG0251	oxidation-reduction process
LDN90_RS06880	COG4565	transcriptional regulatory protein
LDN90_RS06890	COG2851	Citrate transporter
LDN90_RS06895	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LDN90_RS06900	COG0154	amidase activity
LDN90_RS06905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LDN90_RS06920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LDN90_RS06925	COG4209	transmembrane transport
LDN90_RS06930	COG0395	ABC-type sugar transport system, permease component
LDN90_RS06940	COG1609	Transcriptional regulator
LDN90_RS06945	COG0673	inositol 2-dehydrogenase activity
LDN90_RS06955	COG1063	alcohol dehydrogenase
LDN90_RS06960	COG0156	8-amino-7-oxononanoate synthase activity
LDN90_RS06970	COG1228	amidohydrolase
LDN90_RS06995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDN90_RS07000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDN90_RS07005	COG1940	carbohydrate kinase activity
LDN90_RS07025	COG0588	phosphoglycerate mutase activity
LDN90_RS07040	COG2873	o-acetylhomoserine
LDN90_RS07045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDN90_RS07080	COG0423	glycine-tRNA ligase activity
LDN90_RS07110	COG0358	DNA primase activity
LDN90_RS07130	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LDN90_RS07135	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LDN90_RS07145	COG2814	Major facilitator Superfamily
LDN90_RS07155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LDN90_RS07190	COG0052	Belongs to the universal ribosomal protein uS2 family
LDN90_RS07195	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LDN90_RS07200	COG0528	UMP kinase activity
LDN90_RS07205	COG0233	cytoplasmic translational termination
LDN90_RS07210	COG0575	Belongs to the CDS family
LDN90_RS07225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDN90_RS07240	COG3275	phosphorelay sensor kinase activity
LDN90_RS07250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDN90_RS07255	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LDN90_RS07255	COG1796	DNA polymerase
LDN90_RS07275	COG1522	sequence-specific DNA binding
LDN90_RS07285	COG0022	dehydrogenase e1 component
LDN90_RS07290	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN90_RS07295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDN90_RS07310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LDN90_RS07320	COG1960	acyl-CoA dehydrogenase activity
LDN90_RS07345	COG0673	inositol 2-dehydrogenase activity
LDN90_RS07360	COG0673	inositol 2-dehydrogenase activity
LDN90_RS07370	COG1175	transmembrane transport
LDN90_RS07375	COG1653	transport
LDN90_RS07390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LDN90_RS07395	COG0750	zinc metalloprotease
LDN90_RS07405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LDN90_RS07430	COG0442	prolyl-tRNA aminoacylation
LDN90_RS07440	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
LDN90_RS07455	COG0779	Required for maturation of 30S ribosomal subunits
LDN90_RS07460	COG0195	Participates in both transcription termination and antitermination
LDN90_RS07470	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LDN90_RS07470	COG0481	GTPase activity
LDN90_RS07475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LDN90_RS07480	COG0590	tRNA wobble adenosine to inosine editing
LDN90_RS07490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LDN90_RS07510	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LDN90_RS07515	COG1185	polyribonucleotide nucleotidyltransferase activity
LDN90_RS07520	COG0612	Peptidase, M16
LDN90_RS07540	COG0745	RESPONSE REGULATOR receiver
LDN90_RS07545	COG2205	protein histidine kinase activity
LDN90_RS07565	COG0521	Mo-molybdopterin cofactor biosynthetic process
LDN90_RS07575	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LDN90_RS07600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDN90_RS07605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LDN90_RS07610	COG1674	ftsk spoiiie
LDN90_RS07620	COG1058	Belongs to the CinA family
LDN90_RS07620	COG1546	Belongs to the CinA family
LDN90_RS07625	COG1396	sequence-specific DNA binding
LDN90_RS07640	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LDN90_RS07645	COG2137	regulation of response to DNA damage stimulus
LDN90_RS07650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LDN90_RS07655	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LDN90_RS07660	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LDN90_RS07665	COG2813	Specifically methylates the guanine in position
LDN90_RS07670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LDN90_RS07680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LDN90_RS07685	COG1388	LysM domain
LDN90_RS07690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDN90_RS07695	COG0131	Imidazoleglycerol-phosphate dehydratase
LDN90_RS07700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LDN90_RS07710	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LDN90_RS07730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LDN90_RS07735	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LDN90_RS07740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LDN90_RS07745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDN90_RS07755	COG2814	Major facilitator Superfamily
LDN90_RS07790	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LDN90_RS07795	COG0072	phenylalanine-tRNA ligase activity
LDN90_RS07795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDN90_RS07810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LDN90_RS07815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LDN90_RS07820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LDN90_RS07825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LDN90_RS07830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LDN90_RS07835	COG1438	arginine binding
LDN90_RS07840	COG0137	argininosuccinate synthase activity
LDN90_RS07845	COG0165	Argininosuccinate lyase
LDN90_RS07860	COG2094	Belongs to the DNA glycosylase MPG family
LDN90_RS07870	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LDN90_RS07900	COG0647	UMP catabolic process
LDN90_RS07915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LDN90_RS07920	COG0497	DNA recombination
LDN90_RS07925	COG0504	CTP synthase activity
LDN90_RS07955	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LDN90_RS07960	COG2079	MmgE PrpD family protein
LDN90_RS07985	COG3290	protein histidine kinase activity
LDN90_RS07990	COG1301	dicarboxylic acid transport
LDN90_RS08000	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LDN90_RS08005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LDN90_RS08020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LDN90_RS08030	COG1160	GTP binding
LDN90_RS08050	COG2814	Major facilitator Superfamily
LDN90_RS08060	COG0509	glycine decarboxylation via glycine cleavage system
LDN90_RS08065	COG1716	ATPase activity
LDN90_RS08090	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LDN90_RS08100	COG1940	carbohydrate kinase activity
LDN90_RS08125	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LDN90_RS08130	COG0515	serine threonine protein kinase
LDN90_RS08130	COG2815	serine threonine protein kinase
LDN90_RS08135	COG1388	LysM domain
LDN90_RS08135	COG3942	CHAP domain
LDN90_RS08145	COG0142	geranyltranstransferase activity
LDN90_RS08155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LDN90_RS08165	COG2001	Belongs to the MraZ family
LDN90_RS08170	COG0275	rRNA processing
LDN90_RS08180	COG0768	penicillin binding
LDN90_RS08185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LDN90_RS08190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDN90_RS08195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDN90_RS08200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LDN90_RS08210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LDN90_RS08215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LDN90_RS08225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LDN90_RS08230	COG1496	oxidoreductase activity
LDN90_RS08235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LDN90_RS08240	COG1799	cell septum assembly
LDN90_RS08255	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LDN90_RS08280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDN90_RS08285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LDN90_RS08290	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS08310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LDN90_RS08315	COG0174	glutamine synthetase
LDN90_RS08320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LDN90_RS08355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LDN90_RS08360	COG0321	lipoyl(octanoyl) transferase activity
LDN90_RS08375	COG4946	Tricorn protease homolog
LDN90_RS08375	COG0793	Belongs to the peptidase S41A family
LDN90_RS08380	COG1764	response to oxidative stress
LDN90_RS08390	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN90_RS08395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDN90_RS08400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LDN90_RS08420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDN90_RS08430	COG0187	DNA topoisomerase II activity
LDN90_RS08435	COG2814	Major facilitator Superfamily
LDN90_RS08450	COG1271	oxidase subunit
LDN90_RS08455	COG1294	oxidase, subunit
LDN90_RS08460	COG4988	ABC transporter
LDN90_RS08480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LDN90_RS08485	COG0045	succinate-CoA ligase (ADP-forming) activity
LDN90_RS08485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDN90_RS08485	COG1042	CoA-binding domain protein
LDN90_RS08500	COG1435	thymidine kinase activity
LDN90_RS08520	COG0756	dUTP diphosphatase activity
LDN90_RS08545	COG0569	domain protein
LDN90_RS08550	COG0531	amino acid
LDN90_RS08555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDN90_RS08560	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LDN90_RS08565	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LDN90_RS08585	COG0667	Aldo Keto reductase
LDN90_RS08590	COG1024	Enoyl-CoA hydratase
LDN90_RS08590	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN90_RS08595	COG0183	Belongs to the thiolase family
LDN90_RS08625	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDN90_RS08640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LDN90_RS08660	COG3135	benzoate transporter
LDN90_RS08670	COG0531	amino acid
LDN90_RS08735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDN90_RS08735	COG4221	oxidoreductase activity
LDN90_RS08735	COG3321	synthase
LDN90_RS08735	COG0604	alcohol dehydrogenase
LDN90_RS08740	COG0789	Transcriptional regulator
LDN90_RS08745	COG3119	arylsulfatase activity
LDN90_RS08750	COG2271	Major facilitator Superfamily
LDN90_RS08785	COG0242	peptide deformylase activity
LDN90_RS08790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LDN90_RS08800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LDN90_RS08820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDN90_RS08820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDN90_RS08825	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDN90_RS08825	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDN90_RS08830	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LDN90_RS08835	COG0140	phosphoribosyl-ATP diphosphatase activity
LDN90_RS08840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LDN90_RS08845	COG0107	imidazoleglycerol-phosphate synthase activity
LDN90_RS08860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LDN90_RS08880	COG0134	indole-3-glycerol-phosphate synthase activity
LDN90_RS08885	COG0133	tryptophan synthase activity
LDN90_RS08890	COG0159	tryptophan synthase activity
LDN90_RS08895	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LDN90_RS08900	COG0070	glutamate synthase
LDN90_RS08900	COG0069	glutamate synthase activity
LDN90_RS08900	COG0067	glutamate synthase
LDN90_RS08925	COG0582	viral genome integration into host DNA
LDN90_RS09060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LDN90_RS09080	COG2211	Major facilitator Superfamily
LDN90_RS09090	COG1609	Transcriptional regulator
LDN90_RS09095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDN90_RS09125	COG1309	transcriptional regulator
LDN90_RS09130	COG2814	Major facilitator Superfamily
LDN90_RS09135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LDN90_RS09145	COG1609	Transcriptional regulator
LDN90_RS09160	COG4221	oxidoreductase activity
LDN90_RS09170	COG0596	Alpha beta hydrolase
LDN90_RS09180	COG1024	Enoyl-CoA hydratase
LDN90_RS09185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LDN90_RS09200	COG0477	Major facilitator Superfamily
LDN90_RS09210	COG0318	PFAM AMP-dependent synthetase and ligase
LDN90_RS09220	COG0183	Belongs to the thiolase family
LDN90_RS09240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDN90_RS09250	COG1609	Transcriptional regulator
LDN90_RS09255	COG0747	negative chemotaxis
LDN90_RS09260	COG0601	transmembrane transport
LDN90_RS09270	COG4172	Belongs to the ABC transporter superfamily
LDN90_RS09290	COG1609	Transcriptional regulator
LDN90_RS09310	COG1349	DNA-binding transcription factor activity
LDN90_RS09315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LDN90_RS09325	COG0601	transmembrane transport
LDN90_RS09330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN90_RS09335	COG0444	Belongs to the ABC transporter superfamily
LDN90_RS09340	COG4608	Belongs to the ABC transporter superfamily
LDN90_RS09345	COG0667	Aldo Keto reductase
LDN90_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS09390	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS09420	COG0028	Belongs to the TPP enzyme family
LDN90_RS09425	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LDN90_RS09440	COG0318	PFAM AMP-dependent synthetase and ligase
LDN90_RS09455	COG0444	Belongs to the ABC transporter superfamily
LDN90_RS09505	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS09510	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS09520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDN90_RS09575	COG1175	transmembrane transport
LDN90_RS09580	COG0395	ABC-type sugar transport system, permease component
LDN90_RS09585	COG1472	Belongs to the glycosyl hydrolase 3 family
LDN90_RS09590	COG2723	6-phospho-beta-galactosidase activity
LDN90_RS09605	COG0673	inositol 2-dehydrogenase activity
LDN90_RS09610	COG0673	inositol 2-dehydrogenase activity
LDN90_RS09635	COG2124	cytochrome p450
LDN90_RS09645	COG2409	Drug exporters of the RND superfamily
LDN90_RS09650	COG4585	Histidine kinase
LDN90_RS09655	COG2197	response regulator
LDN90_RS09660	COG1472	Belongs to the glycosyl hydrolase 3 family
LDN90_RS09665	COG2723	6-phospho-beta-galactosidase activity
LDN90_RS09670	COG3250	beta-galactosidase activity
LDN90_RS09675	COG1472	Belongs to the glycosyl hydrolase 3 family
LDN90_RS09685	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS09695	COG3250	beta-galactosidase activity
LDN90_RS09700	COG2211	Major facilitator Superfamily
LDN90_RS09705	COG3507	Belongs to the glycosyl hydrolase 43 family
LDN90_RS09735	COG0765	amino acid transport
LDN90_RS09740	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS09745	COG1126	abc transporter atp-binding protein
LDN90_RS09750	COG1126	abc transporter atp-binding protein
LDN90_RS09755	COG1053	succinate dehydrogenase
LDN90_RS09760	COG0477	Major facilitator Superfamily
LDN90_RS09765	COG1234	tRNA 3'-trailer cleavage
LDN90_RS09785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDN90_RS09795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDN90_RS09805	COG1609	Transcriptional regulator
LDN90_RS09815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDN90_RS09820	COG4209	transmembrane transport
LDN90_RS09825	COG0395	ABC-type sugar transport system, permease component
LDN90_RS09840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDN90_RS09860	COG1609	Transcriptional regulator
LDN90_RS09865	COG1609	Transcriptional regulator
LDN90_RS09875	COG0395	ABC-type sugar transport system, permease component
LDN90_RS09880	COG1175	transmembrane transport
LDN90_RS09895	COG1609	Transcriptional regulator
LDN90_RS09965	COG2135	peptidase activity
LDN90_RS09980	COG1063	alcohol dehydrogenase
LDN90_RS10000	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN90_RS10005	COG0318	PFAM AMP-dependent synthetase and ligase
LDN90_RS10010	COG1960	acyl-CoA dehydrogenase activity
LDN90_RS10015	COG1960	acyl-CoA dehydrogenase activity
LDN90_RS10030	COG1024	Enoyl-CoA hydratase
LDN90_RS10030	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN90_RS10035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDN90_RS10065	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LDN90_RS10090	COG1309	transcriptional regulator
LDN90_RS10105	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS10115	COG1053	succinate dehydrogenase
LDN90_RS10125	COG0596	Alpha beta hydrolase
LDN90_RS10130	COG0633	Ferredoxin
LDN90_RS10160	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN90_RS10165	COG1024	Enoyl-CoA hydratase
LDN90_RS10170	COG0183	Belongs to the thiolase family
LDN90_RS10175	COG0702	epimerase
LDN90_RS10185	COG1129	ABC transporter
LDN90_RS10205	COG3384	dioxygenase
LDN90_RS10235	COG3119	arylsulfatase activity
LDN90_RS10250	COG2149	membrane
LDN90_RS10255	COG3265	gluconokinase activity
LDN90_RS10260	COG4948	Mandelate Racemase Muconate Lactonizing
LDN90_RS10265	COG0246	Mannitol dehydrogenase
LDN90_RS10270	COG1904	glucuronate isomerase
LDN90_RS10275	COG1609	Transcriptional regulator
LDN90_RS10280	COG3119	arylsulfatase activity
LDN90_RS10290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN90_RS10300	COG0747	negative chemotaxis
LDN90_RS10305	COG1609	Transcriptional regulator
LDN90_RS10310	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN90_RS10325	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN90_RS10335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LDN90_RS10350	COG3119	arylsulfatase activity
LDN90_RS10360	COG3250	beta-galactosidase activity
LDN90_RS10375	COG0601	transmembrane transport
LDN90_RS10390	COG1414	Transcriptional regulator
LDN90_RS10400	COG2124	cytochrome p450
LDN90_RS10410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDN90_RS10415	COG0251	oxidation-reduction process
LDN90_RS10420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDN90_RS10425	COG0477	Major facilitator Superfamily
LDN90_RS10440	COG1414	Transcriptional regulator
LDN90_RS10470	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDN90_RS10475	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN90_RS10480	COG0145	ligase activity
LDN90_RS10495	COG3962	Belongs to the TPP enzyme family
LDN90_RS10500	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS10505	COG0673	inositol 2-dehydrogenase activity
LDN90_RS10510	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS10515	COG0129	dihydroxy-acid dehydratase activity
LDN90_RS10520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDN90_RS10530	COG0673	inositol 2-dehydrogenase activity
LDN90_RS10535	COG1129	ABC transporter
LDN90_RS10540	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDN90_RS10550	COG0277	FAD linked oxidase domain protein
LDN90_RS10550	COG0247	lactate metabolic process
LDN90_RS10605	COG1609	Transcriptional regulator
LDN90_RS10625	COG2508	Transcriptional regulator
LDN90_RS10630	COG0477	Major facilitator Superfamily
LDN90_RS10635	COG0028	Belongs to the TPP enzyme family
LDN90_RS10640	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS10645	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LDN90_RS10650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDN90_RS10660	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS10675	COG0596	Alpha beta hydrolase
LDN90_RS10705	COG1609	Transcriptional regulator
LDN90_RS10710	COG1082	Xylose isomerase domain protein TIM barrel
LDN90_RS10715	COG2814	Major facilitator Superfamily
LDN90_RS10735	COG0318	PFAM AMP-dependent synthetase and ligase
LDN90_RS10740	COG1960	acyl-CoA dehydrogenase activity
LDN90_RS10745	COG0183	Belongs to the thiolase family
LDN90_RS10750	COG1024	Enoyl-CoA hydratase
LDN90_RS10750	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN90_RS10765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDN90_RS10770	COG2267	carboxylic ester hydrolase activity
LDN90_RS10780	COG1073	alpha beta
LDN90_RS10795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LDN90_RS10815	COG0604	alcohol dehydrogenase
LDN90_RS10820	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS10840	COG0800	Aldolase
LDN90_RS10850	COG1609	Transcriptional regulator
LDN90_RS10890	COG0395	ABC-type sugar transport system, permease component
LDN90_RS10895	COG1175	transmembrane transport
LDN90_RS10905	COG1609	Transcriptional regulator
LDN90_RS10915	COG0747	negative chemotaxis
LDN90_RS10935	COG3250	beta-galactosidase activity
LDN90_RS10940	COG3507	Belongs to the glycosyl hydrolase 43 family
LDN90_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS10980	COG1472	Belongs to the glycosyl hydrolase 3 family
LDN90_RS10995	COG2084	Dehydrogenase
LDN90_RS11000	COG1082	Xylose isomerase domain protein TIM barrel
LDN90_RS11005	COG0149	triose-phosphate isomerase activity
LDN90_RS11010	COG0698	ribose 5-phosphate isomerase
LDN90_RS11015	COG2376	Dihydroxyacetone kinase
LDN90_RS11025	COG2186	Transcriptional regulator
LDN90_RS11050	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LDN90_RS11085	COG0154	amidase activity
LDN90_RS11105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDN90_RS11125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDN90_RS11140	COG0659	secondary active sulfate transmembrane transporter activity
LDN90_RS11170	COG0842	Transport permease protein
LDN90_RS11175	COG1131	(ABC) transporter
LDN90_RS11210	COG1131	(ABC) transporter
LDN90_RS11230	COG0574	Belongs to the PEP-utilizing enzyme family
LDN90_RS11230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDN90_RS11255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LDN90_RS11290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LDN90_RS11320	COG1063	alcohol dehydrogenase
LDN90_RS11325	COG2217	Heavy metal translocating P-type atpase
LDN90_RS11335	COG0280	phosphate acetyltransferase
LDN90_RS11335	COG0857	belongs to the CobB CobQ family
LDN90_RS11345	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LDN90_RS11355	COG0589	response to stress
LDN90_RS11360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LDN90_RS11365	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LDN90_RS11370	COG2132	Multicopper oxidase
LDN90_RS11395	COG2207	Transcriptional regulator
LDN90_RS11400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDN90_RS11435	COG1793	dna ligase
LDN90_RS11445	COG0477	Major facilitator Superfamily
LDN90_RS11450	COG2175	clavaminate synthase activity
LDN90_RS11460	COG2080	2 iron, 2 sulfur cluster binding
LDN90_RS11465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LDN90_RS11475	COG2271	Major facilitator Superfamily
LDN90_RS11480	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS11515	COG0028	Belongs to the TPP enzyme family
LDN90_RS11535	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LDN90_RS11540	COG1846	Transcriptional regulator
LDN90_RS11570	COG2072	flavoprotein involved in K transport
LDN90_RS11575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDN90_RS11595	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS11605	COG0531	amino acid
LDN90_RS11615	COG5016	pyruvate
LDN90_RS11615	COG0511	ligase activity, forming carbon-carbon bonds
LDN90_RS11620	COG0511	ligase activity, forming carbon-carbon bonds
LDN90_RS11625	COG0439	Biotin carboxylase
LDN90_RS11640	COG0183	Belongs to the thiolase family
LDN90_RS11645	COG0318	PFAM AMP-dependent synthetase and ligase
LDN90_RS11650	COG0583	DNA-binding transcription factor activity
LDN90_RS11680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LDN90_RS11690	COG3119	arylsulfatase activity
LDN90_RS11695	COG0747	negative chemotaxis
LDN90_RS11715	COG3119	arylsulfatase activity
LDN90_RS11720	COG3119	arylsulfatase activity
LDN90_RS11730	COG3119	arylsulfatase activity
LDN90_RS11740	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN90_RS11755	COG2814	Major facilitator Superfamily
LDN90_RS11760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDN90_RS11775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDN90_RS11780	COG0464	growth
LDN90_RS11820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDN90_RS11825	COG3619	membrane
LDN90_RS11830	COG2188	Transcriptional regulator
LDN90_RS11835	COG0405	Gamma-glutamyltransferase
LDN90_RS11845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LDN90_RS11855	COG0022	dehydrogenase e1 component
LDN90_RS11860	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN90_RS11870	COG1960	acyl-CoA dehydrogenase activity
LDN90_RS11900	COG2271	Major facilitator Superfamily
LDN90_RS11930	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN90_RS11945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDN90_RS11975	COG1609	Transcriptional regulator
LDN90_RS11980	COG2814	Major facilitator Superfamily
LDN90_RS11995	COG1024	Enoyl-CoA hydratase
LDN90_RS11995	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN90_RS12000	COG0183	Belongs to the thiolase family
LDN90_RS12025	COG1175	transmembrane transport
LDN90_RS12030	COG0395	ABC-type sugar transport system, permease component
LDN90_RS12045	COG1609	Transcriptional regulator
LDN90_RS12060	COG0395	ABC-type sugar transport system, permease component
LDN90_RS12080	COG4176	ABC-type proline glycine betaine transport system permease component
LDN90_RS12085	COG4175	Glycine betaine
LDN90_RS12085	COG0517	IMP dehydrogenase activity
LDN90_RS12090	COG0583	DNA-binding transcription factor activity
LDN90_RS12130	COG2197	response regulator
LDN90_RS12160	COG0028	Belongs to the TPP enzyme family
LDN90_RS12165	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LDN90_RS12175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LDN90_RS12185	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS12205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN90_RS12210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LDN90_RS12320	COG2272	Belongs to the type-B carboxylesterase lipase family
LDN90_RS12360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDN90_RS12365	COG3424	synthase
LDN90_RS12370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDN90_RS12385	COG0242	peptide deformylase activity
LDN90_RS12395	COG2226	methyltransferase
LDN90_RS12415	COG1216	Glycosyl transferase, family 2
LDN90_RS12420	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LDN90_RS12425	COG4581	dead DEAH box helicase
LDN90_RS12430	COG0805	protein transport
LDN90_RS12435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDN90_RS12455	COG0545	Peptidyl-prolyl cis-trans isomerase
LDN90_RS12460	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LDN90_RS12465	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LDN90_RS12470	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LDN90_RS12480	COG4122	O-methyltransferase activity
LDN90_RS12485	COG1222	aaa ATPase
LDN90_RS12495	COG0517	IMP dehydrogenase activity
LDN90_RS12495	COG1994	Peptidase M50
LDN90_RS12500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDN90_RS12510	COG0215	cysteine-tRNA ligase activity
LDN90_RS12515	COG1968	undecaprenyl-diphosphatase activity
LDN90_RS12520	COG0656	L-ascorbic acid biosynthetic process
LDN90_RS12525	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LDN90_RS12530	COG1088	dTDP-glucose 4,6-dehydratase activity
LDN90_RS12590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LDN90_RS12605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDN90_RS12660	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS12665	COG0183	Belongs to the thiolase family
LDN90_RS12680	COG0297	glycogen (starch) synthase activity
LDN90_RS12685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LDN90_RS12710	COG2855	membrane
LDN90_RS12725	COG0254	rRNA binding
LDN90_RS12745	COG0477	Major facilitator Superfamily
LDN90_RS12750	COG1473	amidohydrolase
LDN90_RS12760	COG1522	sequence-specific DNA binding
LDN90_RS12765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LDN90_RS12775	COG1113	amino acid transport
LDN90_RS12785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDN90_RS12795	COG0477	Major facilitator Superfamily
LDN90_RS12800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDN90_RS12840	COG1119	ATPase activity
LDN90_RS12845	COG3830	Belongs to the UPF0237 family
LDN90_RS12845	COG0560	Phosphoserine phosphatase
LDN90_RS12865	COG1129	ABC transporter
LDN90_RS12870	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS12875	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS12900	COG0488	(ABC) transporter
LDN90_RS12905	COG1268	BioY protein
LDN90_RS12910	COG1122	ATPase activity
LDN90_RS12915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LDN90_RS12925	COG0318	PFAM AMP-dependent synthetase and ligase
LDN90_RS12935	COG2151	metal-sulfur cluster biosynthetic enzyme
LDN90_RS12940	COG0396	ATPase activity
LDN90_RS12965	COG1131	(ABC) transporter
LDN90_RS12975	COG1612	heme a metabolic process
LDN90_RS12980	COG0109	protoheme IX farnesyltransferase activity
LDN90_RS12990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LDN90_RS12995	COG0166	Belongs to the GPI family
LDN90_RS13010	COG0363	glucosamine-6-phosphate deaminase activity
LDN90_RS13020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDN90_RS13025	COG0149	triose-phosphate isomerase activity
LDN90_RS13030	COG0126	phosphoglycerate kinase activity
LDN90_RS13035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDN90_RS13040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LDN90_RS13045	COG1481	regulation of sporulation
LDN90_RS13055	COG1660	Displays ATPase and GTPase activities
LDN90_RS13060	COG0322	excinuclease ABC activity
LDN90_RS13070	COG0546	phosphoglycolate phosphatase activity
LDN90_RS13085	COG4106	trans-aconitate 2-methyltransferase activity
LDN90_RS13095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDN90_RS13120	COG0556	nucleotide-excision repair
LDN90_RS13125	COG0237	dephospho-CoA kinase activity
LDN90_RS13125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LDN90_RS13130	COG1739	Uncharacterized protein family UPF0029
LDN90_RS13140	COG0539	negative regulation of cytoplasmic translation
LDN90_RS13150	COG4552	Acetyltransferase involved in intracellular survival and related
LDN90_RS13160	COG2050	protein possibly involved in aromatic compounds catabolism
LDN90_RS13165	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LDN90_RS13195	COG3483	tryptophan 2,3-dioxygenase activity
LDN90_RS13210	COG2188	Transcriptional regulator
LDN90_RS13215	COG2814	Major facilitator Superfamily
LDN90_RS13220	COG2971	BadF BadG BcrA BcrD
LDN90_RS13225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDN90_RS13245	COG0009	L-threonylcarbamoyladenylate synthase
LDN90_RS13290	COG1643	Atp-dependent helicase
LDN90_RS13295	COG1064	alcohol dehydrogenase
LDN90_RS13320	COG3795	YCII-related domain
LDN90_RS13330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDN90_RS13355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LDN90_RS13405	COG0460	homoserine dehydrogenase
LDN90_RS13410	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS13425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDN90_RS13430	COG0028	Belongs to the TPP enzyme family
LDN90_RS13435	COG3285	dna ligase
LDN90_RS13435	COG1793	dna ligase
LDN90_RS13455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LDN90_RS13460	COG1845	cytochrome c oxidase, subunit III
LDN90_RS13465	COG2010	Cytochrome c
LDN90_RS13470	COG0723	plastoquinol--plastocyanin reductase activity
LDN90_RS13475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LDN90_RS13480	COG2188	Transcriptional regulator
LDN90_RS13485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDN90_RS13495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDN90_RS13500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LDN90_RS13520	COG0167	dihydroorotate dehydrogenase activity
LDN90_RS13535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDN90_RS13535	COG0596	Alpha beta hydrolase
LDN90_RS13535	COG2226	methyltransferase
LDN90_RS13540	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LDN90_RS13545	COG1381	Involved in DNA repair and RecF pathway recombination
LDN90_RS13550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDN90_RS13555	COG3590	peptidase
LDN90_RS13560	COG1316	TRANSCRIPTIONal
LDN90_RS13565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LDN90_RS13575	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LDN90_RS13590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LDN90_RS13595	COG0484	heat shock protein binding
LDN90_RS13600	COG1420	regulation of RNA biosynthetic process
LDN90_RS13620	COG0481	GTPase activity
LDN90_RS13630	COG0268	Binds directly to 16S ribosomal RNA
LDN90_RS13655	COG1307	EDD domain protein, DegV family
LDN90_RS13660	COG0495	leucyl-tRNA aminoacylation
LDN90_RS13665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LDN90_RS13670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LDN90_RS13675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDN90_RS13680	COG2390	Transcriptional regulator
LDN90_RS13685	COG0656	L-ascorbic acid biosynthetic process
LDN90_RS13705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LDN90_RS13715	COG1758	RNA polymerase activity
LDN90_RS13720	COG0194	GDP metabolic process
LDN90_RS13730	COG0284	orotidine-5'-phosphate decarboxylase activity
LDN90_RS13735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LDN90_RS13740	COG0505	Belongs to the CarA family
LDN90_RS13750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDN90_RS13755	COG0540	Belongs to the ATCase OTCase family
LDN90_RS13760	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LDN90_RS13770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDN90_RS13775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LDN90_RS13785	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LDN90_RS13790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LDN90_RS13795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LDN90_RS13800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDN90_RS13815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LDN90_RS13830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LDN90_RS13845	COG0456	acetyltransferase
LDN90_RS13850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LDN90_RS13855	COG0124	histidyl-tRNA synthetase
LDN90_RS13865	COG1196	nuclear chromosome segregation
LDN90_RS13875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDN90_RS13880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDN90_RS13885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDN90_RS13895	COG2255	four-way junction helicase activity
LDN90_RS13900	COG0632	four-way junction helicase activity
LDN90_RS13905	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LDN90_RS13910	COG0217	transcriptional regulatory protein
LDN90_RS13915	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LDN90_RS13945	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LDN90_RS13950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LDN90_RS13960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LDN90_RS13965	COG0587	DNA-directed DNA polymerase activity
LDN90_RS13990	COG2135	peptidase activity
LDN90_RS14025	COG0723	plastoquinol--plastocyanin reductase activity
LDN90_RS14035	COG4804	nuclease activity
LDN90_RS14055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDN90_RS14060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDN90_RS14065	COG1780	Probably involved in ribonucleotide reductase function
LDN90_RS14075	COG0583	DNA-binding transcription factor activity
LDN90_RS14115	COG0714	Associated with various cellular activities
LDN90_RS14125	COG3833	ABC-type maltose transport systems, permease component
LDN90_RS14130	COG1175	transmembrane transport
LDN90_RS14145	COG2813	Specifically methylates the guanine in position
LDN90_RS14170	COG0799	negative regulation of ribosome biogenesis
LDN90_RS14180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LDN90_RS14190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LDN90_RS14195	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LDN90_RS14200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LDN90_RS14205	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LDN90_RS14210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LDN90_RS14215	COG0352	thiamine-phosphate diphosphorylase activity
LDN90_RS14215	COG0351	phosphomethylpyrimidine kinase
LDN90_RS14215	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LDN90_RS14220	COG1530	ribonuclease E activity
LDN90_RS14230	COG0105	UTP biosynthetic process
LDN90_RS14240	COG0285	dihydrofolate synthase activity
LDN90_RS14245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LDN90_RS14260	COG0525	valine-tRNA ligase activity
LDN90_RS14265	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDN90_RS14270	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LDN90_RS14275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LDN90_RS14280	COG0740	serine-type endopeptidase activity
LDN90_RS14285	COG0740	serine-type endopeptidase activity
LDN90_RS14290	COG0544	peptidyl-prolyl cis-trans isomerase activity
LDN90_RS14340	COG0668	transmembrane transport
LDN90_RS14355	COG1946	Acyl-CoA thioesterase
LDN90_RS14380	COG0629	single-stranded DNA binding
LDN90_RS14410	COG0242	peptide deformylase activity
LDN90_RS14440	COG3022	response to hydroperoxide
LDN90_RS14450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDN90_RS14455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDN90_RS14465	COG1045	serine acetyltransferase
LDN90_RS14470	COG0300	oxidoreductase activity
LDN90_RS14475	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LDN90_RS14485	COG1063	alcohol dehydrogenase
LDN90_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS14500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDN90_RS14505	COG0477	Major facilitator Superfamily
LDN90_RS14540	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LDN90_RS14555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDN90_RS14560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDN90_RS14575	COG4974	Belongs to the 'phage' integrase family
LDN90_RS14770	COG0085	RNA polymerase activity
LDN90_RS14800	COG1793	dna ligase
LDN90_RS14865	COG1074	ATP-dependent DNA helicase activity
LDN90_RS14875	COG0542	response to heat
LDN90_RS14940	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS14950	COG0500	methyltransferase
LDN90_RS15035	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LDN90_RS15130	COG0750	zinc metalloprotease
LDN90_RS15360	COG0210	DNA helicase
LDN90_RS15380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LDN90_RS15465	COG1595	DNA-templated transcription, initiation
LDN90_RS15500	COG1607	acyl-coa hydrolase
LDN90_RS15505	COG0583	DNA-binding transcription factor activity
LDN90_RS15515	COG1960	acyl-CoA dehydrogenase activity
LDN90_RS15525	COG1024	Enoyl-CoA hydratase
LDN90_RS15530	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN90_RS15550	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS15560	COG0657	acetylesterase activity
LDN90_RS15585	COG0477	Major facilitator Superfamily
LDN90_RS15605	COG2197	response regulator
LDN90_RS15610	COG4585	Histidine kinase
LDN90_RS15630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LDN90_RS15630	COG0517	IMP dehydrogenase activity
LDN90_RS15635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LDN90_RS15645	COG0792	nuclease activity
LDN90_RS15655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LDN90_RS15665	COG0681	Belongs to the peptidase S26 family
LDN90_RS15670	COG0335	large ribosomal subunit rRNA binding
LDN90_RS15675	COG0336	Belongs to the RNA methyltransferase TrmD family
LDN90_RS15680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LDN90_RS15685	COG1837	Belongs to the UPF0109 family
LDN90_RS15690	COG0228	four-way junction DNA binding
LDN90_RS15700	COG2514	catechol 2,3-dioxygenase activity
LDN90_RS15725	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LDN90_RS15740	COG2814	Major facilitator Superfamily
LDN90_RS15780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDN90_RS15785	COG0571	ribonuclease III activity
LDN90_RS15790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LDN90_RS15800	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LDN90_RS15815	COG0742	ribosomal rna small subunit methyltransferase
LDN90_RS15840	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDN90_RS15845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LDN90_RS15855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LDN90_RS15860	COG0066	3-isopropylmalate dehydratase activity
LDN90_RS15865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LDN90_RS15870	COG1414	Transcriptional regulator
LDN90_RS15905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDN90_RS15910	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN90_RS15920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDN90_RS15925	COG0473	3-isopropylmalate dehydrogenase activity
LDN90_RS15930	COG4585	Histidine kinase
LDN90_RS15935	COG2197	response regulator
LDN90_RS15940	COG1136	(ABC) transporter
LDN90_RS15940	COG0577	efflux transmembrane transporter activity
LDN90_RS15945	COG2177	Part of the ABC transporter FtsEX involved in
LDN90_RS15955	COG0577	efflux transmembrane transporter activity
LDN90_RS15955	COG1136	(ABC) transporter
LDN90_RS15965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDN90_RS15970	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LDN90_RS15975	COG0440	acetolactate synthase activity
LDN90_RS15985	COG0129	dihydroxy-acid dehydratase activity
LDN90_RS15990	COG0088	Forms part of the polypeptide exit tunnel
LDN90_RS15995	COG2133	pyrroloquinoline quinone binding
LDN90_RS16030	COG0747	negative chemotaxis
LDN90_RS16035	COG0579	oxidoreductase
LDN90_RS16040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDN90_RS16045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN90_RS16055	COG1305	Transglutaminase-like
LDN90_RS16085	COG1104	cysteine desulfurase activity
LDN90_RS16095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LDN90_RS16100	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LDN90_RS16110	COG1522	sequence-specific DNA binding
LDN90_RS16115	COG1113	amino acid transport
LDN90_RS16125	COG0022	dehydrogenase e1 component
LDN90_RS16130	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN90_RS16150	COG0477	Major facilitator Superfamily
LDN90_RS16180	COG1116	anion transmembrane transporter activity
LDN90_RS16185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDN90_RS16215	COG0419	ATPase involved in DNA repair
LDN90_RS16220	COG0420	3'-5' exonuclease activity
LDN90_RS16235	COG2149	membrane
LDN90_RS16255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LDN90_RS16260	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LDN90_RS16265	COG1234	tRNA 3'-trailer cleavage
LDN90_RS16270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LDN90_RS16280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LDN90_RS16290	COG1335	isochorismatase
LDN90_RS16305	COG0363	glucosamine-6-phosphate deaminase activity
LDN90_RS16320	COG1902	pentaerythritol trinitrate reductase activity
LDN90_RS16335	COG0628	permease
LDN90_RS16350	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LDN90_RS16365	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LDN90_RS16370	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LDN90_RS16380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LDN90_RS16385	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LDN90_RS16390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LDN90_RS16395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LDN90_RS16400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDN90_RS16405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LDN90_RS16410	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDN90_RS16415	COG0356	it plays a direct role in the translocation of protons across the membrane
LDN90_RS16430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDN90_RS16450	COG2890	protein-(glutamine-N5) methyltransferase activity
LDN90_RS16455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LDN90_RS16465	COG0083	homoserine kinase activity
LDN90_RS16470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LDN90_RS16475	COG0460	homoserine dehydrogenase
LDN90_RS16480	COG0019	diaminopimelate decarboxylase activity
LDN90_RS16485	COG0018	arginyl-trna synthetase
LDN90_RS16500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDN90_RS16500	COG1017	nitric oxide dioxygenase activity
LDN90_RS16530	COG1643	Atp-dependent helicase
LDN90_RS16535	COG0537	adenosine 5'-monophosphoramidase activity
LDN90_RS16540	COG1064	alcohol dehydrogenase
LDN90_RS16570	COG1121	(ABC) transporter
LDN90_RS16585	COG1253	flavin adenine dinucleotide binding
LDN90_RS16590	COG0567	Dehydrogenase, E1 component
LDN90_RS16590	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN90_RS16615	COG1595	DNA-templated transcription, initiation
LDN90_RS16625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LDN90_RS16635	COG0483	inositol monophosphate 1-phosphatase activity
LDN90_RS16640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDN90_RS16675	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LDN90_RS16685	COG2177	Part of the ABC transporter FtsEX involved in
LDN90_RS16690	COG2884	Cell division ATP-binding protein ftsE
LDN90_RS16695	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LDN90_RS16785	COG1216	Glycosyl transferase, family 2
LDN90_RS16800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LDN90_RS16830	COG2902	Dehydrogenase
LDN90_RS16865	COG0653	protein targeting
LDN90_RS16870	COG3214	Protein conserved in bacteria
LDN90_RS16875	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LDN90_RS16890	COG5401	PFAM Sporulation and spore germination
LDN90_RS16895	COG5002	protein histidine kinase activity
LDN90_RS16900	COG0745	RESPONSE REGULATOR receiver
LDN90_RS16920	COG0714	Associated with various cellular activities
LDN90_RS16955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN90_RS16960	COG0601	transmembrane transport
LDN90_RS16980	COG0482	sulfurtransferase activity
LDN90_RS17015	COG0484	heat shock protein binding
LDN90_RS17020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LDN90_RS17040	COG3265	gluconokinase activity
LDN90_RS17050	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LDN90_RS17055	COG2086	electron transfer activity
LDN90_RS17060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDN90_RS17070	COG1842	Phage shock protein A
LDN90_RS17075	COG2188	Transcriptional regulator
LDN90_RS17090	COG1615	UPF0182 protein
LDN90_RS17095	COG3480	Lon protease (S16) C-terminal proteolytic domain
LDN90_RS17115	COG2816	NAD+ diphosphatase activity
LDN90_RS17145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN90_RS17150	COG0765	amino acid transport
LDN90_RS17155	COG1126	abc transporter atp-binding protein
LDN90_RS17160	COG1472	Belongs to the glycosyl hydrolase 3 family
LDN90_RS17165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDN90_RS17175	COG0113	porphobilinogen synthase activity
LDN90_RS17185	COG0181	hydroxymethylbilane synthase activity
LDN90_RS17190	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LDN90_RS17195	COG3253	May function as heme-dependent peroxidase
LDN90_RS17200	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LDN90_RS17205	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LDN90_RS17210	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LDN90_RS17225	COG1309	transcriptional regulator
LDN90_RS17255	COG2022	thiamine diphosphate biosynthetic process
LDN90_RS17255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDN90_RS17260	COG0352	thiamine-phosphate diphosphorylase activity
LDN90_RS17275	COG0513	Belongs to the DEAD box helicase family
LDN90_RS17295	COG0006	proline dipeptidase activity
LDN90_RS17305	COG2239	Acts as a magnesium transporter
LDN90_RS17320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDN90_RS17330	COG1595	DNA-templated transcription, initiation
LDN90_RS17360	COG1126	abc transporter atp-binding protein
LDN90_RS17365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN90_RS17370	COG0765	amino acid transport
LDN90_RS17375	COG0765	amino acid transport
LDN90_RS17380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDN90_RS17385	COG2171	N-acyltransferase activity
LDN90_RS17400	COG3226	Transcriptional regulator
LDN90_RS17405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LDN90_RS17435	COG1217	gtp-binding protein TYPA
LDN90_RS17450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN90_RS17455	COG0601	transmembrane transport
LDN90_RS17465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LDN90_RS17490	COG0012	GTP binding
LDN90_RS17495	COG1322	Protein conserved in bacteria
LDN90_RS17500	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LDN90_RS17510	COG1570	exodeoxyribonuclease VII activity
LDN90_RS17515	COG1722	exodeoxyribonuclease VII activity
LDN90_RS17520	COG2326	polyphosphate kinase activity
LDN90_RS17540	COG1174	glycine betaine transport
LDN90_RS17570	COG2971	BadF BadG BcrA BcrD
LDN90_RS17580	COG0583	DNA-binding transcription factor activity
LDN90_RS17585	COG2814	Major facilitator Superfamily
LDN90_RS17590	COG3548	integral membrane protein
LDN90_RS17615	COG0598	Magnesium transport protein CorA
LDN90_RS17625	COG1528	Iron-storage protein
LDN90_RS17630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDN90_RS17635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDN90_RS17645	COG2824	Alkylphosphonate utilization operon protein PhnA
LDN90_RS17650	COG1278	Cold shock
LDN90_RS17685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LDN90_RS17690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LDN90_RS17710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDN90_RS17710	COG0519	Catalyzes the synthesis of GMP from XMP
LDN90_RS17730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDN90_RS17735	COG0516	GMP reductase activity
LDN90_RS17740	COG1132	(ABC) transporter
LDN90_RS17760	COG2072	flavoprotein involved in K transport
LDN90_RS17770	COG2197	response regulator
LDN90_RS17775	COG0459	protein refolding
LDN90_RS17780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LDN90_RS17795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDN90_RS17800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LDN90_RS17810	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LDN90_RS17815	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LDN90_RS17820	COG0456	acetyltransferase
LDN90_RS17830	COG0802	atpase or kinase
LDN90_RS17835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDN90_RS17855	COG0438	transferase activity, transferring glycosyl groups
LDN90_RS17860	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LDN90_RS17870	COG0667	Aldo Keto reductase
LDN90_RS17895	COG0736	holo-[acyl-carrier-protein] synthase activity
LDN90_RS17905	COG1072	(Pantothenic acid kinase))
LDN90_RS17915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDN90_RS17920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LDN90_RS17925	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LDN90_RS17955	COG0455	bacterial-type flagellum organization
LDN90_RS17975	COG0101	tRNA pseudouridine synthase activity
LDN90_RS17980	COG0203	ribosomal protein L17
LDN90_RS17985	COG0202	RNA polymerase activity
LDN90_RS17990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LDN90_RS17995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LDN90_RS18000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LDN90_RS18005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LDN90_RS18010	COG3191	aminopeptidase activity
LDN90_RS18025	COG0318	PFAM AMP-dependent synthetase and ligase
LDN90_RS18030	COG2124	cytochrome p450
LDN90_RS18035	COG1216	Glycosyl transferase, family 2
LDN90_RS18040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDN90_RS18045	COG0563	adenylate kinase activity
LDN90_RS18055	COG0200	Binds to the 23S rRNA
LDN90_RS18060	COG1841	ribosomal large subunit assembly
LDN90_RS18065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LDN90_RS18075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LDN90_RS18080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LDN90_RS18085	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LDN90_RS18090	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LDN90_RS18095	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LDN90_RS18100	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LDN90_RS18110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LDN90_RS18115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LDN90_RS18120	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LDN90_RS18125	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LDN90_RS18130	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LDN90_RS18135	COG0089	rRNA binding
LDN90_RS18140	COG0088	Forms part of the polypeptide exit tunnel
LDN90_RS18145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LDN90_RS18150	COG0051	transcription antitermination factor activity, RNA binding
LDN90_RS18165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDN90_RS18170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LDN90_RS18175	COG0049	tRNA binding
LDN90_RS18180	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LDN90_RS18185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LDN90_RS18190	COG0085	RNA polymerase activity
LDN90_RS18195	COG0183	Belongs to the thiolase family
LDN90_RS18200	COG0442	prolyl-tRNA aminoacylation
LDN90_RS18210	COG0222	ribosome binding
LDN90_RS18215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LDN90_RS18230	COG0081	regulation of translation
LDN90_RS18235	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LDN90_RS18245	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDN90_RS18255	COG0436	Aminotransferase
LDN90_RS18260	COG2197	response regulator
LDN90_RS18305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDN90_RS18315	COG3485	protocatechuate 3,4-dioxygenase
LDN90_RS18325	COG0745	RESPONSE REGULATOR receiver
LDN90_RS18330	COG0456	acetyltransferase
LDN90_RS18335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LDN90_RS18345	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LDN90_RS18350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LDN90_RS18360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDN90_RS18380	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LDN90_RS18385	COG2030	dehydratase
LDN90_RS18390	COG2030	dehydratase
LDN90_RS18425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDN90_RS18435	COG4989	oxidoreductase activity
LDN90_RS18440	COG0366	Alpha amylase catalytic
LDN90_RS18445	COG0395	ABC-type sugar transport system, permease component
LDN90_RS18450	COG1175	transmembrane transport
LDN90_RS18460	COG1940	carbohydrate kinase activity
LDN90_RS18515	COG0754	glutathionylspermidine amidase activity
LDN90_RS18525	COG5650	phosphatidylinositol metabolic process
LDN90_RS18545	COG5650	phosphatidylinositol metabolic process
LDN90_RS18575	COG0318	PFAM AMP-dependent synthetase and ligase
LDN90_RS18585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDN90_RS18595	COG1309	transcriptional regulator
LDN90_RS18600	COG1131	(ABC) transporter
LDN90_RS18620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LDN90_RS18635	COG1666	GTP binding
LDN90_RS18640	COG0672	)-iron permease
LDN90_RS18650	COG2837	iron assimilation
LDN90_RS18655	COG0501	Belongs to the peptidase M48B family
LDN90_RS18685	COG0531	amino acid
LDN90_RS18735	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS18740	COG3835	regulator
LDN90_RS18745	COG2807	transmembrane transport
LDN90_RS18750	COG2186	Transcriptional regulator
LDN90_RS18755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDN90_RS18755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDN90_RS18770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDN90_RS18770	COG1648	precorrin-2 dehydrogenase activity
LDN90_RS18775	COG2066	Belongs to the glutaminase family
LDN90_RS18795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN90_RS18805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDN90_RS18810	COG1116	anion transmembrane transporter activity
LDN90_RS18820	COG2040	homocysteine
LDN90_RS18840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDN90_RS18850	COG2860	membrane
LDN90_RS18865	COG0142	geranyltranstransferase activity
LDN90_RS18875	COG2226	methyltransferase
LDN90_RS18880	COG1169	isochorismate synthase
LDN90_RS18890	COG0765	amino acid transport
LDN90_RS18900	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LDN90_RS18905	COG1609	Transcriptional regulator
LDN90_RS18915	COG1175	transmembrane transport
LDN90_RS18920	COG0395	ABC-type sugar transport system, permease component
LDN90_RS18940	COG4948	Mandelate Racemase Muconate Lactonizing
LDN90_RS18960	COG1609	Transcriptional regulator
LDN90_RS18965	COG1621	beta-fructofuranosidase activity
LDN90_RS18970	COG0395	ABC-type sugar transport system, permease component
LDN90_RS18975	COG1175	transmembrane transport
LDN90_RS18985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDN90_RS19055	COG1404	Belongs to the peptidase S8 family
LDN90_RS19060	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN90_RS19065	COG0022	dehydrogenase e1 component
LDN90_RS19090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LDN90_RS19120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LDN90_RS19130	COG1134	teichoic acid transport
LDN90_RS19140	COG0438	transferase activity, transferring glycosyl groups
LDN90_RS19160	COG1316	TRANSCRIPTIONal
LDN90_RS19195	COG0489	protein tyrosine kinase activity
LDN90_RS19220	COG1216	Glycosyl transferase, family 2
LDN90_RS19220	COG1442	glycosyl transferase family 8
LDN90_RS19235	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LDN90_RS19240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDN90_RS19250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LDN90_RS19270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LDN90_RS19305	COG2828	Protein conserved in bacteria
LDN90_RS19310	COG0583	DNA-binding transcription factor activity
LDN90_RS19315	COG0671	phosphoesterase, PA-phosphatase related
LDN90_RS19330	COG5002	protein histidine kinase activity
LDN90_RS19335	COG0745	RESPONSE REGULATOR receiver
LDN90_RS19360	COG2894	cell division
LDN90_RS19390	COG5002	protein histidine kinase activity
LDN90_RS19400	COG0667	Aldo Keto reductase
LDN90_RS19405	COG1609	Transcriptional regulator
LDN90_RS19425	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LDN90_RS19430	COG1024	Enoyl-CoA hydratase
LDN90_RS19435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDN90_RS19440	COG2151	metal-sulfur cluster biosynthetic enzyme
LDN90_RS19445	COG3396	Phenylacetate-CoA oxygenase
LDN90_RS19450	COG3460	Phenylacetate-CoA oxygenase
LDN90_RS19455	COG3396	Phenylacetate-CoA oxygenase
LDN90_RS19465	COG1388	LysM domain
LDN90_RS19465	COG3942	CHAP domain
LDN90_RS19480	COG2203	Gaf domain
LDN90_RS19480	COG3706	GGDEF domain
LDN90_RS19480	COG4251	negative regulation of phosphorylation
LDN90_RS19480	COG5001	Diguanylate cyclase
LDN90_RS19505	COG4106	trans-aconitate 2-methyltransferase activity
LDN90_RS19515	COG5002	protein histidine kinase activity
LDN90_RS19540	COG2050	protein possibly involved in aromatic compounds catabolism
LDN90_RS19560	COG0477	Major facilitator Superfamily
LDN90_RS19565	COG3119	arylsulfatase activity
LDN90_RS19575	COG1609	Transcriptional regulator
LDN90_RS19580	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS19580	COG2030	dehydratase
LDN90_RS19590	COG1609	Transcriptional regulator
LDN90_RS19605	COG0395	ABC-type sugar transport system, permease component
LDN90_RS19615	COG0673	inositol 2-dehydrogenase activity
LDN90_RS19620	COG0673	inositol 2-dehydrogenase activity
LDN90_RS19640	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN90_RS19645	COG1024	Enoyl-CoA hydratase
LDN90_RS19650	COG0183	Belongs to the thiolase family
LDN90_RS19670	COG2146	nitrite reductase [NAD(P)H] activity
LDN90_RS19675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDN90_RS19685	COG0488	(ABC) transporter
LDN90_RS19690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDN90_RS19695	COG1121	(ABC) transporter
LDN90_RS19700	COG0803	Belongs to the bacterial solute-binding protein 9 family
LDN90_RS19705	COG1266	CAAX protease self-immunity
LDN90_RS19710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LDN90_RS19740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDN90_RS19750	COG0785	Cytochrome C biogenesis protein
LDN90_RS19760	COG0406	alpha-ribazole phosphatase activity
LDN90_RS19780	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LDN90_RS19810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDN90_RS19815	COG3458	cephalosporin-C deacetylase activity
LDN90_RS19825	COG2755	lipolytic protein G-D-S-L family
LDN90_RS19830	COG0395	ABC-type sugar transport system, permease component
LDN90_RS19835	COG4209	transmembrane transport
LDN90_RS19840	COG1653	transport
LDN90_RS19850	COG5578	integral membrane protein
LDN90_RS19860	COG2814	Major facilitator Superfamily
LDN90_RS19870	COG0395	ABC-type sugar transport system, permease component
LDN90_RS19875	COG1175	transmembrane transport
LDN90_RS19895	COG0395	ABC-type sugar transport system, permease component
LDN90_RS19900	COG1175	transmembrane transport
LDN90_RS19925	COG4948	Mandelate Racemase Muconate Lactonizing
LDN90_RS19930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDN90_RS19940	COG0673	inositol 2-dehydrogenase activity
LDN90_RS19945	COG1609	Transcriptional regulator
LDN90_RS19950	COG2186	Transcriptional regulator
LDN90_RS19960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LDN90_RS19965	COG0640	Transcriptional regulator
LDN90_RS19975	COG0123	including yeast histone deacetylase and acetoin utilization protein
LDN90_RS19985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDN90_RS19990	COG0569	domain protein
LDN90_RS19995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDN90_RS20000	COG1082	Xylose isomerase domain protein TIM barrel
LDN90_RS20005	COG0248	Ppx GppA phosphatase
LDN90_RS20015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDN90_RS20015	COG1754	DNA topoisomerase type I activity
LDN90_RS20025	COG2890	protein-(glutamine-N5) methyltransferase activity
LDN90_RS20040	COG1054	Belongs to the UPF0176 family
LDN90_RS20050	COG1111	helicase
LDN90_RS20050	COG1205	dead DEAH box helicase
LDN90_RS20120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDN90_RS20125	COG1349	DNA-binding transcription factor activity
LDN90_RS20130	COG0577	efflux transmembrane transporter activity
LDN90_RS20130	COG1136	(ABC) transporter
LDN90_RS20140	COG1609	Transcriptional regulator
LDN90_RS20150	COG1175	transmembrane transport
LDN90_RS20155	COG0395	ABC-type sugar transport system, permease component
LDN90_RS20200	COG4499	WXG100 protein secretion system (Wss), protein YukC
LDN90_RS20200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDN90_RS20205	COG1408	metallophosphoesterase
LDN90_RS20210	COG1132	(ABC) transporter
LDN90_RS20215	COG1132	(ABC) transporter
LDN90_RS20235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LDN90_RS20240	COG0151	Belongs to the GarS family
LDN90_RS20255	COG1301	dicarboxylic acid transport
LDN90_RS20260	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS20270	COG1953	Uracil, thiamine, allantoin
LDN90_RS20275	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LDN90_RS20290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LDN90_RS20290	COG2080	2 iron, 2 sulfur cluster binding
LDN90_RS20300	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LDN90_RS20300	COG3608	succinylglutamate desuccinylase aspartoacylase
LDN90_RS20305	COG2252	PERMEase
LDN90_RS20310	COG0590	tRNA wobble adenosine to inosine editing
LDN90_RS20335	COG2233	PERMEase
LDN90_RS20345	COG1414	Transcriptional regulator
LDN90_RS20355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LDN90_RS20365	COG3257	ureidoglycine aminohydrolase activity
LDN90_RS20380	COG4585	Histidine kinase
LDN90_RS20385	COG4499	WXG100 protein secretion system (Wss), protein YukC
LDN90_RS20385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDN90_RS20410	COG0659	secondary active sulfate transmembrane transporter activity
LDN90_RS20430	COG0563	adenylate kinase activity
LDN90_RS20445	COG3401	FG-GAP repeat protein
LDN90_RS20510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LDN90_RS20520	COG1733	regulation of RNA biosynthetic process
LDN90_RS20550	COG2267	carboxylic ester hydrolase activity
LDN90_RS20605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDN90_RS20610	COG1024	Enoyl-CoA hydratase
LDN90_RS20625	COG0405	Gamma-glutamyltransferase
LDN90_RS20650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LDN90_RS20670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDN90_RS20695	COG0477	Major facilitator Superfamily
LDN90_RS20700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDN90_RS20710	COG0583	DNA-binding transcription factor activity
LDN90_RS20740	COG0673	inositol 2-dehydrogenase activity
LDN90_RS20755	COG1653	transport
LDN90_RS20760	COG1609	Transcriptional regulator
LDN90_RS20765	COG1132	(ABC) transporter
LDN90_RS20780	COG2022	thiamine diphosphate biosynthetic process
LDN90_RS20780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDN90_RS20785	COG0546	phosphoglycolate phosphatase activity
LDN90_RS20790	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LDN90_RS20800	COG0673	inositol 2-dehydrogenase activity
LDN90_RS20805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LDN90_RS20830	COG3622	Belongs to the hyi family
LDN90_RS20835	COG2084	Dehydrogenase
LDN90_RS20840	COG3960	tartronate-semialdehyde synthase activity
LDN90_RS20845	COG1929	Belongs to the glycerate kinase type-1 family
LDN90_RS20850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDN90_RS20855	COG0745	RESPONSE REGULATOR receiver
LDN90_RS20865	COG0745	RESPONSE REGULATOR receiver
LDN90_RS20870	COG1215	transferase activity, transferring glycosyl groups
LDN90_RS20875	COG1366	Belongs to the anti-sigma-factor antagonist family
LDN90_RS20900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LDN90_RS20905	COG0671	phosphoesterase, PA-phosphatase related
LDN90_RS20930	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LDN90_RS20955	COG0542	response to heat
LDN90_RS20980	COG3585	molybdate ion transport
LDN90_RS21000	COG3304	Inner membrane component domain
LDN90_RS21010	COG0135	phosphoribosylanthranilate isomerase activity
LDN90_RS21025	COG2076	Multidrug Resistance protein
LDN90_RS21030	COG0667	Aldo Keto reductase
LDN90_RS21060	COG0500	methyltransferase
LDN90_RS21070	COG1473	amidohydrolase
LDN90_RS21075	COG0477	Major facilitator Superfamily
LDN90_RS21080	COG2807	transmembrane transport
LDN90_RS21090	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LDN90_RS21165	COG1609	Transcriptional regulator
LDN90_RS21175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDN90_RS21180	COG1653	transport
LDN90_RS21185	COG1175	transmembrane transport
LDN90_RS21190	COG0395	ABC-type sugar transport system, permease component
LDN90_RS21225	COG0789	Transcriptional regulator
LDN90_RS21230	COG0484	heat shock protein binding
LDN90_RS21235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LDN90_RS21240	COG0443	Heat shock 70 kDa protein
LDN90_RS21250	COG3739	integral membrane protein
LDN90_RS21325	COG0436	Aminotransferase
LDN90_RS21350	COG0531	amino acid
LDN90_RS21365	COG3226	Transcriptional regulator
LDN90_RS21370	COG1280	lysine exporter protein (LysE YggA)
LDN90_RS21375	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS21385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDN90_RS21395	COG0492	ferredoxin-NADP+ reductase activity
LDN90_RS21400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDN90_RS21425	COG3848	Pyruvate phosphate dikinase
LDN90_RS21425	COG0574	Belongs to the PEP-utilizing enzyme family
LDN90_RS21430	COG2409	Drug exporters of the RND superfamily
LDN90_RS21445	COG3795	YCII-related domain
LDN90_RS21450	COG4941	Belongs to the sigma-70 factor family
LDN90_RS21455	COG0667	Aldo Keto reductase
LDN90_RS21465	COG1280	lysine exporter protein (LysE YggA)
LDN90_RS21470	COG1609	Transcriptional regulator
LDN90_RS21475	COG1957	nucleoside hydrolase
LDN90_RS21480	COG0477	Major facilitator Superfamily
LDN90_RS21485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDN90_RS21495	COG1309	transcriptional regulator
LDN90_RS21500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDN90_RS21510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDN90_RS21520	COG0833	amino acid
LDN90_RS21525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LDN90_RS21535	COG2986	histidine ammonia-lyase
LDN90_RS21565	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LDN90_RS21570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LDN90_RS21580	COG1122	ATPase activity
LDN90_RS21585	COG4721	ABC-type cobalt transport system, permease component
LDN90_RS21600	COG1320	monovalent cation:proton antiporter activity
LDN90_RS21605	COG2212	antiporter activity
LDN90_RS21610	COG1863	multisubunit Na H antiporter MnhE subunit
LDN90_RS21615	COG0651	ATP synthesis coupled electron transport
LDN90_RS21620	COG1006	Multisubunit Na H antiporter MnhC subunit
LDN90_RS21625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LDN90_RS21625	COG2111	Na H antiporter
LDN90_RS21640	COG0475	glutathione-regulated potassium exporter activity
LDN90_RS21645	COG0717	Belongs to the dCTP deaminase family
LDN90_RS21685	COG0583	DNA-binding transcription factor activity
LDN90_RS21705	COG1609	Transcriptional regulator
LDN90_RS21710	COG0673	inositol 2-dehydrogenase activity
LDN90_RS21735	COG1295	ribonuclease BN
LDN90_RS21745	COG2115	Belongs to the xylose isomerase family
LDN90_RS21750	COG1070	Carbohydrate kinase
LDN90_RS21755	COG1609	Transcriptional regulator
LDN90_RS21770	COG2160	L-arabinose isomerase activity
LDN90_RS21775	COG2017	converts alpha-aldose to the beta-anomer
LDN90_RS21785	COG3254	rhamnose metabolic process
LDN90_RS21795	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS21795	COG3347	Dehydrogenase
LDN90_RS21800	COG1070	Carbohydrate kinase
LDN90_RS21810	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LDN90_RS21845	COG3387	PFAM Glycoside hydrolase 15-related
LDN90_RS21850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN90_RS21855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LDN90_RS21885	COG0433	COG0433 Predicted ATPase
LDN90_RS21910	COG0776	regulation of translation
LDN90_RS21960	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LDN90_RS21965	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LDN90_RS21970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LDN90_RS21975	COG1017	nitric oxide dioxygenase activity
LDN90_RS21975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDN90_RS22015	COG1120	ATPase activity
LDN90_RS22020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDN90_RS22025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDN90_RS22070	COG3012	SEC-C Motif Domain Protein
LDN90_RS22085	COG0667	Aldo Keto reductase
LDN90_RS22135	COG2186	Transcriptional regulator
LDN90_RS22145	COG1027	Aspartate ammonia-lyase
LDN90_RS22160	COG3618	amidohydrolase
LDN90_RS22170	COG3254	rhamnose metabolic process
LDN90_RS22180	COG4948	Mandelate Racemase Muconate Lactonizing
LDN90_RS22190	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS22205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LDN90_RS22240	COG4221	oxidoreductase activity
LDN90_RS22250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LDN90_RS22255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDN90_RS22270	COG1914	H( )-stimulated, divalent metal cation uptake system
LDN90_RS22275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDN90_RS22280	COG1609	Transcriptional regulator
LDN90_RS22335	COG0640	Transcriptional regulator
LDN90_RS22350	COG1414	Transcriptional regulator
LDN90_RS22360	COG0477	Major facilitator Superfamily
LDN90_RS22370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDN90_RS22395	COG1760	l-serine dehydratase
LDN90_RS22415	COG0726	polysaccharide deacetylase
LDN90_RS22425	COG0281	malic enzyme
LDN90_RS22430	COG1309	transcriptional regulator
LDN90_RS22460	COG2211	Major facilitator Superfamily
LDN90_RS22470	COG0477	Major facilitator Superfamily
LDN90_RS22475	COG2986	histidine ammonia-lyase
LDN90_RS22480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LDN90_RS22495	COG1174	glycine betaine transport
LDN90_RS22510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDN90_RS22520	COG0477	Major facilitator Superfamily
LDN90_RS22525	COG2814	Major facilitator Superfamily
LDN90_RS22530	COG1846	Transcriptional regulator
LDN90_RS22575	COG1113	amino acid transport
LDN90_RS22580	COG0246	Mannitol dehydrogenase
LDN90_RS22585	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDN90_RS22585	COG2213	PTS system mannitol-specific
LDN90_RS22595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDN90_RS22600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDN90_RS22615	COG4608	Belongs to the ABC transporter superfamily
LDN90_RS22620	COG0444	Belongs to the ABC transporter superfamily
LDN90_RS22625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN90_RS22630	COG0601	transmembrane transport
LDN90_RS22635	COG0747	negative chemotaxis
LDN90_RS22660	COG0596	Alpha beta hydrolase
LDN90_RS22670	COG1793	dna ligase
LDN90_RS22690	COG0686	Belongs to the AlaDH PNT family
LDN90_RS22720	COG0673	inositol 2-dehydrogenase activity
LDN90_RS22745	COG1309	transcriptional regulator
LDN90_RS22775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDN90_RS22795	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN90_RS22800	COG0022	dehydrogenase e1 component
LDN90_RS22810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDN90_RS22815	COG1950	PFAM Membrane protein of
LDN90_RS22830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LDN90_RS22835	COG0406	alpha-ribazole phosphatase activity
LDN90_RS22845	COG1607	acyl-coa hydrolase
LDN90_RS22860	COG3971	2-oxopent-4-enoate hydratase activity
LDN90_RS22875	COG1802	Transcriptional regulator
LDN90_RS22880	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN90_RS22900	COG2261	transglycosylase associated protein
LDN90_RS22910	COG3708	Transcriptional regulator
LDN90_RS22910	COG2207	Transcriptional regulator
LDN90_RS22920	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS22940	COG0477	Major facilitator Superfamily
LDN90_RS22945	COG1609	Transcriptional regulator
LDN90_RS22960	COG0395	ABC-type sugar transport system, permease component
LDN90_RS22970	COG5492	domain, Protein
LDN90_RS22990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDN90_RS23005	COG0515	serine threonine protein kinase
LDN90_RS23005	COG2815	serine threonine protein kinase
LDN90_RS23055	COG3387	PFAM Glycoside hydrolase 15-related
LDN90_RS23065	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
LDN90_RS23115	COG2814	Major facilitator Superfamily
LDN90_RS23135	COG0243	molybdopterin cofactor binding
LDN90_RS23185	COG0515	serine threonine protein kinase
LDN90_RS23185	COG2815	serine threonine protein kinase
LDN90_RS23190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LDN90_RS23195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LDN90_RS23200	COG1760	l-serine dehydratase
LDN90_RS23205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDN90_RS23210	COG0509	glycine decarboxylation via glycine cleavage system
LDN90_RS23215	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDN90_RS23220	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDN90_RS23220	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDN90_RS23235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LDN90_RS23240	COG1012	belongs to the aldehyde dehydrogenase family
LDN90_RS23250	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS23270	COG1970	mechanosensitive ion channel activity
LDN90_RS23280	COG2271	Major facilitator Superfamily
LDN90_RS23285	COG1802	Transcriptional regulator
LDN90_RS23295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDN90_RS23345	COG0546	phosphoglycolate phosphatase activity
LDN90_RS23350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDN90_RS23370	COG2814	Major facilitator Superfamily
LDN90_RS23395	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN90_RS23400	COG0251	oxidation-reduction process
LDN90_RS23410	COG1414	Transcriptional regulator
LDN90_RS23415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LDN90_RS23425	COG0183	Belongs to the thiolase family
LDN90_RS23430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LDN90_RS23450	COG3485	protocatechuate 3,4-dioxygenase
LDN90_RS23455	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LDN90_RS23455	COG1082	Xylose isomerase domain protein TIM barrel
LDN90_RS23460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDN90_RS23465	COG1414	Transcriptional regulator
LDN90_RS23485	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LDN90_RS23495	COG0646	methionine synthase
LDN90_RS23495	COG1410	methionine synthase
LDN90_RS23500	COG3845	ABC transporter
LDN90_RS23520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LDN90_RS23525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN90_RS23540	COG0251	oxidation-reduction process
LDN90_RS23550	COG1028	Short-chain dehydrogenase reductase Sdr
LDN90_RS23555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDN90_RS23560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN90_RS23595	COG2610	gluconate transmembrane transporter activity
LDN90_RS23605	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LDN90_RS23620	COG1414	Transcriptional regulator
LDN90_RS23685	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LDN90_RS23700	COG0277	FAD linked oxidase domain protein
LDN90_RS23705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDN90_RS23710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LDN90_RS23745	COG0596	Alpha beta hydrolase
LDN90_RS23750	COG1937	Protein conserved in bacteria
LDN90_RS23795	COG0534	Mate efflux family protein
LDN90_RS23805	COG2259	Doxx family
LDN90_RS23820	COG3848	Pyruvate phosphate dikinase
LDN90_RS23820	COG0574	Belongs to the PEP-utilizing enzyme family
LDN90_RS23830	COG1607	acyl-coa hydrolase
LDN90_RS23845	COG0305	Participates in initiation and elongation during chromosome replication
LDN90_RS23885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDN90_RS23890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDN90_RS23910	COG1414	Transcriptional regulator
LDN90_RS23925	COG0359	binds to the 23S rRNA
LDN90_RS23930	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LDN90_RS23940	COG0360	Binds together with S18 to 16S ribosomal RNA
LDN90_RS23960	COG1113	amino acid transport
LDN90_RS23965	COG1362	aminopeptidase activity
LDN90_RS23995	COG0833	amino acid
LDN90_RS24000	COG2197	response regulator
LDN90_RS24005	COG4585	Histidine kinase
LDN90_RS24015	COG1131	(ABC) transporter
LDN90_RS24020	COG1597	lipid kinase activity
LDN90_RS24030	COG0738	Major facilitator superfamily
LDN90_RS24040	COG0488	(ABC) transporter
LDN90_RS24055	COG2197	response regulator
LDN90_RS24060	COG4585	Histidine kinase
LDN90_RS24070	COG1136	(ABC) transporter
LDN90_RS24075	COG1733	regulation of RNA biosynthetic process
LDN90_RS24080	COG2910	NAD(P)H-binding
LDN90_RS24100	COG0406	alpha-ribazole phosphatase activity
LDN90_RS24105	COG0617	tRNA 3'-terminal CCA addition
LDN90_RS24125	COG0492	ferredoxin-NADP+ reductase activity
LDN90_RS24130	COG3118	belongs to the thioredoxin family
LDN90_RS24140	COG1192	Involved in chromosome partitioning
LDN90_RS24145	COG0357	Ribosomal RNA small subunit methyltransferase G
LDN90_RS24155	COG0706	membrane insertase activity
LDN90_RS24160	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LDN90_RS24165	COG0594	ribonuclease P activity
LDN90_RS24170	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LDN90_RS24260	COG2610	gluconate transmembrane transporter activity