locus-tag	class	description
BWQ92_RS00015	COG2161	toxin-antitoxin pair type II binding
BWQ92_RS00080	COG2079	MmgE PrpD family protein
BWQ92_RS00085	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BWQ92_RS00095	COG0563	adenylate kinase activity
BWQ92_RS00105	COG0604	alcohol dehydrogenase
BWQ92_RS00140	COG0583	DNA-binding transcription factor activity
BWQ92_RS00145	COG2161	toxin-antitoxin pair type II binding
BWQ92_RS00150	COG2026	Addiction module toxin, RelE StbE family
BWQ92_RS00160	COG0596	Alpha beta hydrolase
BWQ92_RS00310	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BWQ92_RS00310	COG5479	isomerase activity
BWQ92_RS00480	COG2161	toxin-antitoxin pair type II binding
BWQ92_RS00520	COG0477	Major facilitator Superfamily
BWQ92_RS00525	COG1063	alcohol dehydrogenase
BWQ92_RS00535	COG0596	Alpha beta hydrolase
BWQ92_RS00550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BWQ92_RS00555	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS00560	COG0583	DNA-binding transcription factor activity
BWQ92_RS00580	COG0477	Major facilitator Superfamily
BWQ92_RS00585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWQ92_RS00595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWQ92_RS00615	COG1937	Protein conserved in bacteria
BWQ92_RS00685	COG2132	Multicopper oxidase
BWQ92_RS00745	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BWQ92_RS00750	COG0785	Cytochrome C biogenesis protein
BWQ92_RS00775	COG0640	Transcriptional regulator
BWQ92_RS00790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BWQ92_RS00790	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BWQ92_RS00855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWQ92_RS00900	COG0785	Cytochrome C biogenesis protein
BWQ92_RS00905	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BWQ92_RS00920	COG2124	cytochrome p450
BWQ92_RS00925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWQ92_RS00935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWQ92_RS00945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWQ92_RS00965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BWQ92_RS00980	COG0739	heme binding
BWQ92_RS01035	COG0288	reversible hydration of carbon dioxide
BWQ92_RS01060	COG2801	Transposase and inactivated derivatives
BWQ92_RS01105	COG2217	Heavy metal translocating P-type atpase
BWQ92_RS01120	COG0785	Cytochrome C biogenesis protein
BWQ92_RS01145	COG0501	Belongs to the peptidase M48B family
BWQ92_RS01160	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BWQ92_RS01170	COG2372	response to copper ion
BWQ92_RS01195	COG1937	Protein conserved in bacteria
BWQ92_RS01210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWQ92_RS01220	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWQ92_RS01225	COG3764	Sortase (surface protein transpeptidase)
BWQ92_RS01275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BWQ92_RS01345	COG0484	heat shock protein binding
BWQ92_RS01455	COG0469	pyruvate kinase activity
BWQ92_RS01465	COG0070	glutamate synthase
BWQ92_RS01465	COG0067	glutamate synthase
BWQ92_RS01465	COG0069	glutamate synthase activity
BWQ92_RS01470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BWQ92_RS01475	COG0159	tryptophan synthase activity
BWQ92_RS01480	COG0133	tryptophan synthase activity
BWQ92_RS01485	COG0134	indole-3-glycerol-phosphate synthase activity
BWQ92_RS01505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BWQ92_RS01520	COG0107	imidazoleglycerol-phosphate synthase activity
BWQ92_RS01525	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BWQ92_RS01530	COG0140	phosphoribosyl-ATP diphosphatase activity
BWQ92_RS01535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BWQ92_RS01540	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BWQ92_RS01540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BWQ92_RS01545	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BWQ92_RS01545	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BWQ92_RS01565	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BWQ92_RS01575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BWQ92_RS01580	COG0242	peptide deformylase activity
BWQ92_RS01640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BWQ92_RS01655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWQ92_RS01680	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BWQ92_RS01685	COG2801	Transposase and inactivated derivatives
BWQ92_RS01685	COG3415	Transposase
BWQ92_RS01690	COG1024	Enoyl-CoA hydratase
BWQ92_RS01690	COG1250	3-hydroxyacyl-CoA dehydrogenase
BWQ92_RS01695	COG1122	ATPase activity
BWQ92_RS01715	COG0667	Aldo Keto reductase
BWQ92_RS01735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BWQ92_RS01740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BWQ92_RS01745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BWQ92_RS01750	COG0531	amino acid
BWQ92_RS01755	COG0569	domain protein
BWQ92_RS01780	COG0756	dUTP diphosphatase activity
BWQ92_RS01800	COG1435	thymidine kinase activity
BWQ92_RS01815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWQ92_RS01815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWQ92_RS01820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BWQ92_RS01830	COG0456	acetyltransferase
BWQ92_RS01840	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BWQ92_RS01845	COG4988	ABC transporter
BWQ92_RS01850	COG3415	Transposase
BWQ92_RS01850	COG2801	Transposase and inactivated derivatives
BWQ92_RS01860	COG1294	oxidase, subunit
BWQ92_RS01865	COG1271	oxidase subunit
BWQ92_RS01895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BWQ92_RS01915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BWQ92_RS01920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWQ92_RS01925	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWQ92_RS01935	COG1764	response to oxidative stress
BWQ92_RS01940	COG4946	Tricorn protease homolog
BWQ92_RS01940	COG0793	Belongs to the peptidase S41A family
BWQ92_RS01945	COG1090	epimerase
BWQ92_RS01955	COG0321	lipoyl(octanoyl) transferase activity
BWQ92_RS01960	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BWQ92_RS02025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BWQ92_RS02030	COG0174	glutamine synthetase
BWQ92_RS02035	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BWQ92_RS02050	COG1609	Transcriptional regulator
BWQ92_RS02060	COG0395	ABC-type sugar transport system, permease component
BWQ92_RS02065	COG1175	transmembrane transport
BWQ92_RS02075	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BWQ92_RS02080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BWQ92_RS02095	COG0587	DNA-directed DNA polymerase activity
BWQ92_RS02105	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BWQ92_RS02110	COG3599	regulation of cell shape
BWQ92_RS02120	COG1799	cell septum assembly
BWQ92_RS02125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BWQ92_RS02135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BWQ92_RS02145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BWQ92_RS02150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BWQ92_RS02160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BWQ92_RS02165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BWQ92_RS02170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BWQ92_RS02180	COG0768	penicillin binding
BWQ92_RS02190	COG0275	rRNA processing
BWQ92_RS02195	COG2001	Belongs to the MraZ family
BWQ92_RS02205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BWQ92_RS02215	COG0142	geranyltranstransferase activity
BWQ92_RS02225	COG3942	CHAP domain
BWQ92_RS02225	COG1388	LysM domain
BWQ92_RS02230	COG2815	serine threonine protein kinase
BWQ92_RS02230	COG0515	serine threonine protein kinase
BWQ92_RS02235	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BWQ92_RS02260	COG1940	carbohydrate kinase activity
BWQ92_RS02275	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BWQ92_RS02280	COG1192	Involved in chromosome partitioning
BWQ92_RS02300	COG1716	ATPase activity
BWQ92_RS02305	COG0509	glycine decarboxylation via glycine cleavage system
BWQ92_RS02310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BWQ92_RS02320	COG1160	GTP binding
BWQ92_RS02330	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BWQ92_RS02345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BWQ92_RS02350	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BWQ92_RS02360	COG1301	dicarboxylic acid transport
BWQ92_RS02365	COG3290	protein histidine kinase activity
BWQ92_RS02385	COG2079	MmgE PrpD family protein
BWQ92_RS02390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BWQ92_RS02410	COG0494	nUDIX hydrolase
BWQ92_RS02415	COG0504	CTP synthase activity
BWQ92_RS02420	COG0497	DNA recombination
BWQ92_RS02425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BWQ92_RS02475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BWQ92_RS02485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BWQ92_RS02490	COG2094	Belongs to the DNA glycosylase MPG family
BWQ92_RS02500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BWQ92_RS02500	COG2169	Transcriptional regulator
BWQ92_RS02510	COG0165	Argininosuccinate lyase
BWQ92_RS02515	COG0137	argininosuccinate synthase activity
BWQ92_RS02520	COG1438	arginine binding
BWQ92_RS02525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BWQ92_RS02530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BWQ92_RS02535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BWQ92_RS02540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BWQ92_RS02545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BWQ92_RS02565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWQ92_RS02565	COG0072	phenylalanine-tRNA ligase activity
BWQ92_RS02570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BWQ92_RS02580	COG2968	Membrane
BWQ92_RS02585	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BWQ92_RS02600	COG2814	Major facilitator Superfamily
BWQ92_RS02610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWQ92_RS02615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BWQ92_RS02620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BWQ92_RS02625	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BWQ92_RS02645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BWQ92_RS02650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BWQ92_RS02655	COG0131	Imidazoleglycerol-phosphate dehydratase
BWQ92_RS02660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BWQ92_RS02670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BWQ92_RS02680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BWQ92_RS02685	COG2813	Specifically methylates the guanine in position
BWQ92_RS02690	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BWQ92_RS02700	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BWQ92_RS02705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BWQ92_RS02710	COG2137	regulation of response to DNA damage stimulus
BWQ92_RS02715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BWQ92_RS02730	COG1396	sequence-specific DNA binding
BWQ92_RS02735	COG1058	Belongs to the CinA family
BWQ92_RS02735	COG1546	Belongs to the CinA family
BWQ92_RS02745	COG1674	ftsk spoiiie
BWQ92_RS02750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BWQ92_RS02775	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BWQ92_RS02785	COG0521	Mo-molybdopterin cofactor biosynthetic process
BWQ92_RS02825	COG0612	Peptidase, M16
BWQ92_RS02830	COG1185	polyribonucleotide nucleotidyltransferase activity
BWQ92_RS02835	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BWQ92_RS02845	COG3483	tryptophan 2,3-dioxygenase activity
BWQ92_RS02870	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BWQ92_RS02875	COG0436	Aminotransferase
BWQ92_RS02880	COG0590	tRNA wobble adenosine to inosine editing
BWQ92_RS02905	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BWQ92_RS02910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BWQ92_RS02925	COG0779	Required for maturation of 30S ribosomal subunits
BWQ92_RS02940	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
BWQ92_RS02955	COG0442	prolyl-tRNA aminoacylation
BWQ92_RS02965	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BWQ92_RS02985	COG0750	zinc metalloprotease
BWQ92_RS02990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BWQ92_RS03000	COG0542	response to heat
BWQ92_RS03025	COG1960	acyl-CoA dehydrogenase activity
BWQ92_RS03035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BWQ92_RS03045	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWQ92_RS03050	COG0022	dehydrogenase e1 component
BWQ92_RS03060	COG1522	sequence-specific DNA binding
BWQ92_RS03080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWQ92_RS03090	COG3275	phosphorelay sensor kinase activity
BWQ92_RS03105	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWQ92_RS03120	COG0233	cytoplasmic translational termination
BWQ92_RS03125	COG0528	UMP kinase activity
BWQ92_RS03130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BWQ92_RS03135	COG0052	Belongs to the universal ribosomal protein uS2 family
BWQ92_RS03145	COG1960	acyl-CoA dehydrogenase activity
BWQ92_RS03155	COG0438	transferase activity, transferring glycosyl groups
BWQ92_RS03165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BWQ92_RS03175	COG2814	Major facilitator Superfamily
BWQ92_RS03200	COG0358	DNA primase activity
BWQ92_RS03235	COG0423	glycine-tRNA ligase activity
BWQ92_RS03250	COG0400	carboxylic ester hydrolase activity
BWQ92_RS03295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BWQ92_RS03300	COG2873	o-acetylhomoserine
BWQ92_RS03325	COG1228	amidohydrolase
BWQ92_RS03335	COG0156	8-amino-7-oxononanoate synthase activity
BWQ92_RS03340	COG1063	alcohol dehydrogenase
BWQ92_RS03345	COG0583	DNA-binding transcription factor activity
BWQ92_RS03350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BWQ92_RS03355	COG0154	amidase activity
BWQ92_RS03360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BWQ92_RS03365	COG2851	Citrate transporter
BWQ92_RS03375	COG4565	transcriptional regulatory protein
BWQ92_RS03395	COG0483	inositol monophosphate 1-phosphatase activity
BWQ92_RS03400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BWQ92_RS03410	COG1674	ftsk spoiiie
BWQ92_RS03430	COG0631	protein serine/threonine phosphatase activity
BWQ92_RS03450	COG0714	Associated with various cellular activities
BWQ92_RS03470	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BWQ92_RS03470	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BWQ92_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS03480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BWQ92_RS03495	COG1823	symporter activity
BWQ92_RS03500	COG0596	Alpha beta hydrolase
BWQ92_RS03515	COG2409	Drug exporters of the RND superfamily
BWQ92_RS03520	COG0424	maF-like protein
BWQ92_RS03525	COG4770	biotin carboxylase activity
BWQ92_RS03530	COG0477	Major facilitator Superfamily
BWQ92_RS03535	COG2223	nitrite transmembrane transporter activity
BWQ92_RS03540	COG0243	molybdopterin cofactor binding
BWQ92_RS03575	COG1959	2 iron, 2 sulfur cluster binding
BWQ92_RS03580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWQ92_RS03590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWQ92_RS03610	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BWQ92_RS03620	COG1988	membrane-bound metal-dependent
BWQ92_RS03630	COG0702	epimerase
BWQ92_RS03645	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BWQ92_RS03650	COG0822	iron-sulfur transferase activity
BWQ92_RS03670	COG0193	aminoacyl-tRNA hydrolase activity
BWQ92_RS03675	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BWQ92_RS03680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BWQ92_RS03685	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BWQ92_RS03695	COG1309	transcriptional regulator
BWQ92_RS03700	COG0488	(ABC) transporter
BWQ92_RS03705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BWQ92_RS03710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BWQ92_RS03725	COG3583	domain protein
BWQ92_RS03730	COG0084	hydrolase, TatD family'
BWQ92_RS03735	COG0714	Associated with various cellular activities
BWQ92_RS03750	COG0477	Major facilitator Superfamily
BWQ92_RS03790	COG1376	ErfK ybiS ycfS ynhG family protein
BWQ92_RS03795	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BWQ92_RS03845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BWQ92_RS03855	COG1482	cell wall glycoprotein biosynthetic process
BWQ92_RS03885	COG1494	fructose-1,6-bisphosphatase
BWQ92_RS03895	COG0288	reversible hydration of carbon dioxide
BWQ92_RS03900	COG0114	fumarate hydratase activity
BWQ92_RS03925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BWQ92_RS03930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BWQ92_RS03940	COG1331	Highly conserved protein containing a thioredoxin domain
BWQ92_RS03950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BWQ92_RS03960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWQ92_RS03970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BWQ92_RS03980	COG2017	converts alpha-aldose to the beta-anomer
BWQ92_RS03985	COG1349	DNA-binding transcription factor activity
BWQ92_RS03995	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BWQ92_RS04000	COG0183	Belongs to the thiolase family
BWQ92_RS04045	COG1252	NADH dehydrogenase
BWQ92_RS04070	COG0148	phosphopyruvate hydratase activity
BWQ92_RS04075	COG3956	TIGRFAM MazG family protein
BWQ92_RS04080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BWQ92_RS04085	COG0586	Pfam SNARE associated Golgi protein
BWQ92_RS04105	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BWQ92_RS04105	COG1473	amidohydrolase
BWQ92_RS04115	COG2009	succinate dehydrogenase
BWQ92_RS04130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BWQ92_RS04150	COG0180	Tryptophanyl-tRNA synthetase
BWQ92_RS04175	COG1131	(ABC) transporter
BWQ92_RS04185	COG2197	response regulator
BWQ92_RS04190	COG4585	Histidine kinase
BWQ92_RS04195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BWQ92_RS04200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BWQ92_RS04230	COG0531	amino acid
BWQ92_RS04260	COG4213	ABC transporter substrate-binding protein
BWQ92_RS04270	COG1136	(ABC) transporter
BWQ92_RS04275	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS04290	COG0515	serine threonine protein kinase
BWQ92_RS04310	COG2838	Isocitrate dehydrogenase
BWQ92_RS04320	COG0138	bifunctional purine biosynthesis protein purh
BWQ92_RS04325	COG0477	Major facilitator Superfamily
BWQ92_RS04330	COG1570	exodeoxyribonuclease VII activity
BWQ92_RS04380	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BWQ92_RS04410	COG2268	Band 7 protein
BWQ92_RS04425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BWQ92_RS04460	COG2815	serine threonine protein kinase
BWQ92_RS04460	COG0515	serine threonine protein kinase
BWQ92_RS04510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWQ92_RS04530	COG0473	3-isopropylmalate dehydrogenase activity
BWQ92_RS04535	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS04540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWQ92_RS04555	COG0765	amino acid transport
BWQ92_RS04560	COG1126	abc transporter atp-binding protein
BWQ92_RS04570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BWQ92_RS04580	COG1802	Transcriptional regulator
BWQ92_RS04585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWQ92_RS04590	COG0765	amino acid transport
BWQ92_RS04605	COG0277	FAD linked oxidase domain protein
BWQ92_RS04605	COG0247	lactate metabolic process
BWQ92_RS04630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWQ92_RS04635	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS04645	COG0251	oxidation-reduction process
BWQ92_RS04655	COG2610	gluconate transmembrane transporter activity
BWQ92_RS04660	COG3265	gluconokinase activity
BWQ92_RS04690	COG1278	Cold shock
BWQ92_RS04715	COG3387	PFAM Glycoside hydrolase 15-related
BWQ92_RS04740	COG1063	alcohol dehydrogenase
BWQ92_RS04745	COG0395	ABC-type sugar transport system, permease component
BWQ92_RS04765	COG1070	Carbohydrate kinase
BWQ92_RS04770	COG4942	peptidase
BWQ92_RS04795	COG2337	Toxic component of a toxin-antitoxin (TA) module
BWQ92_RS04805	COG2186	Transcriptional regulator
BWQ92_RS04840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BWQ92_RS04855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWQ92_RS04860	COG1414	Transcriptional regulator
BWQ92_RS04865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWQ92_RS04865	COG1116	anion transmembrane transporter activity
BWQ92_RS04870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWQ92_RS04875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWQ92_RS04895	COG1063	alcohol dehydrogenase
BWQ92_RS04900	COG2072	flavoprotein involved in K transport
BWQ92_RS04905	COG3284	Transcriptional regulator
BWQ92_RS04915	COG0477	Major facilitator Superfamily
BWQ92_RS04920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWQ92_RS04960	COG0210	DNA helicase
BWQ92_RS04965	COG1201	RNA secondary structure unwinding
BWQ92_RS05080	COG0477	Major facilitator Superfamily
BWQ92_RS05115	COG0477	Major facilitator Superfamily
BWQ92_RS05125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWQ92_RS05130	COG0531	amino acid
BWQ92_RS05135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWQ92_RS05170	COG1253	flavin adenine dinucleotide binding
BWQ92_RS05195	COG2197	response regulator
BWQ92_RS05205	COG2072	flavoprotein involved in K transport
BWQ92_RS05210	COG0300	oxidoreductase activity
BWQ92_RS05225	COG2375	cellular response to nickel ion
BWQ92_RS05230	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BWQ92_RS05235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWQ92_RS05240	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWQ92_RS05245	COG1120	ATPase activity
BWQ92_RS05255	COG2828	Protein conserved in bacteria
BWQ92_RS05305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWQ92_RS05375	COG3265	gluconokinase activity
BWQ92_RS05385	COG0477	Major facilitator Superfamily
BWQ92_RS05390	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BWQ92_RS05435	COG1063	alcohol dehydrogenase
BWQ92_RS05440	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS05470	COG0640	Transcriptional regulator
BWQ92_RS05490	COG2353	YceI-like domain
BWQ92_RS05505	COG1063	alcohol dehydrogenase
BWQ92_RS05520	COG1254	Belongs to the acylphosphatase family
BWQ92_RS05535	COG3103	Sh3 type 3 domain protein
BWQ92_RS05535	COG0366	Alpha amylase catalytic
BWQ92_RS05550	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS05555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BWQ92_RS05565	COG3583	domain protein
BWQ92_RS05585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWQ92_RS05610	COG0405	Gamma-glutamyltransferase
BWQ92_RS05635	COG0149	triose-phosphate isomerase activity
BWQ92_RS05640	COG2271	Major facilitator Superfamily
BWQ92_RS05645	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS05650	COG1250	3-hydroxyacyl-CoA dehydrogenase
BWQ92_RS05655	COG0698	ribose 5-phosphate isomerase
BWQ92_RS05660	COG2376	Dihydroxyacetone kinase
BWQ92_RS05695	COG1902	pentaerythritol trinitrate reductase activity
BWQ92_RS05720	COG0745	RESPONSE REGULATOR receiver
BWQ92_RS05725	COG5002	protein histidine kinase activity
BWQ92_RS05730	COG1309	transcriptional regulator
BWQ92_RS05745	COG1401	restriction endodeoxyribonuclease activity
BWQ92_RS05780	COG0028	Belongs to the TPP enzyme family
BWQ92_RS05790	COG1396	sequence-specific DNA binding
BWQ92_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS05830	COG2186	Transcriptional regulator
BWQ92_RS05835	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BWQ92_RS05840	COG2188	Transcriptional regulator
BWQ92_RS05845	COG3718	enzyme involved in inositol metabolism
BWQ92_RS05850	COG2814	Major facilitator Superfamily
BWQ92_RS05855	COG1846	Transcriptional regulator
BWQ92_RS05860	COG2814	Major facilitator Superfamily
BWQ92_RS05865	COG1082	Xylose isomerase domain protein TIM barrel
BWQ92_RS05870	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS05885	COG3962	Belongs to the TPP enzyme family
BWQ92_RS05895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWQ92_RS05900	COG1942	4-Oxalocrotonate Tautomerase
BWQ92_RS05915	COG0045	succinate-CoA ligase (ADP-forming) activity
BWQ92_RS05930	COG0483	inositol monophosphate 1-phosphatase activity
BWQ92_RS05955	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BWQ92_RS05960	COG1132	(ABC) transporter
BWQ92_RS05965	COG0488	(ABC) transporter
BWQ92_RS05990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWQ92_RS05995	COG0765	amino acid transport
BWQ92_RS06000	COG1126	abc transporter atp-binding protein
BWQ92_RS06010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BWQ92_RS06025	COG0746	molybdenum cofactor guanylyltransferase activity
BWQ92_RS06035	COG1388	LysM domain
BWQ92_RS06035	COG0791	NLP P60 protein
BWQ92_RS06035	COG3103	Sh3 type 3 domain protein
BWQ92_RS06045	COG0739	heme binding
BWQ92_RS06065	COG1278	Cold shock
BWQ92_RS06080	COG1061	Type III restriction enzyme res subunit
BWQ92_RS06085	COG0745	RESPONSE REGULATOR receiver
BWQ92_RS06090	COG2205	protein histidine kinase activity
BWQ92_RS06100	COG0328	RNA-DNA hybrid ribonuclease activity
BWQ92_RS06105	COG0459	protein refolding
BWQ92_RS06130	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BWQ92_RS06150	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BWQ92_RS06160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BWQ92_RS06165	COG0509	glycine decarboxylation via glycine cleavage system
BWQ92_RS06170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BWQ92_RS06175	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWQ92_RS06175	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWQ92_RS06185	COG0477	Major facilitator Superfamily
BWQ92_RS06190	COG0783	Belongs to the Dps family
BWQ92_RS06195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWQ92_RS06200	COG2957	Belongs to the agmatine deiminase family
BWQ92_RS06225	COG3949	Membrane
BWQ92_RS06230	COG2271	Major facilitator Superfamily
BWQ92_RS06240	COG2814	Major facilitator Superfamily
BWQ92_RS06250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWQ92_RS06260	COG2271	Major facilitator Superfamily
BWQ92_RS06265	COG1113	amino acid transport
BWQ92_RS06270	COG0583	DNA-binding transcription factor activity
BWQ92_RS06285	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS06290	COG0277	FAD linked oxidase domain protein
BWQ92_RS06380	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS06400	COG0477	Major facilitator Superfamily
BWQ92_RS06405	COG2072	flavoprotein involved in K transport
BWQ92_RS06410	COG0583	DNA-binding transcription factor activity
BWQ92_RS06445	COG0583	DNA-binding transcription factor activity
BWQ92_RS06450	COG1126	abc transporter atp-binding protein
BWQ92_RS06455	COG0765	amino acid transport
BWQ92_RS06460	COG0765	amino acid transport
BWQ92_RS06475	COG0583	DNA-binding transcription factor activity
BWQ92_RS06480	COG2271	Major facilitator Superfamily
BWQ92_RS06485	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS06490	COG2072	flavoprotein involved in K transport
BWQ92_RS06500	COG2814	Major facilitator Superfamily
BWQ92_RS06515	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS06525	COG1172	Belongs to the binding-protein-dependent transport system permease family
BWQ92_RS06550	COG1802	Transcriptional regulator
BWQ92_RS06555	COG2801	Transposase and inactivated derivatives
BWQ92_RS06570	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BWQ92_RS06580	COG0589	response to stress
BWQ92_RS06595	COG1802	Transcriptional regulator
BWQ92_RS06615	COG0698	ribose 5-phosphate isomerase
BWQ92_RS06620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWQ92_RS06625	COG1609	Transcriptional regulator
BWQ92_RS06655	COG3842	ATPase activity
BWQ92_RS06665	COG0277	FAD linked oxidase domain protein
BWQ92_RS06690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BWQ92_RS06700	COG0366	Alpha amylase catalytic
BWQ92_RS06730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWQ92_RS06735	COG0215	cysteine-tRNA ligase activity
BWQ92_RS06745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BWQ92_RS06750	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BWQ92_RS06770	COG5002	protein histidine kinase activity
BWQ92_RS06780	COG0588	phosphoglycerate mutase activity
BWQ92_RS06800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BWQ92_RS06805	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BWQ92_RS06845	COG2261	transglycosylase associated protein
BWQ92_RS06865	COG0656	L-ascorbic acid biosynthetic process
BWQ92_RS06890	COG1966	Carbon starvation protein
BWQ92_RS06900	COG0604	alcohol dehydrogenase
BWQ92_RS06920	COG1505	serine-type exopeptidase activity
BWQ92_RS06935	COG0514	ATP-dependent DNA helicase (RecQ)
BWQ92_RS06940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWQ92_RS06955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWQ92_RS06955	COG1017	nitric oxide dioxygenase activity
BWQ92_RS06960	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BWQ92_RS06990	COG2062	phosphohistidine phosphatase, SixA
BWQ92_RS07000	COG0745	RESPONSE REGULATOR receiver
BWQ92_RS07005	COG2205	protein histidine kinase activity
BWQ92_RS07020	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BWQ92_RS07035	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BWQ92_RS07040	COG0671	phosphoesterase, PA-phosphatase related
BWQ92_RS07055	COG0438	transferase activity, transferring glycosyl groups
BWQ92_RS07080	COG3655	Transcriptional regulator
BWQ92_RS07095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWQ92_RS07105	COG0723	plastoquinol--plastocyanin reductase activity
BWQ92_RS07110	COG1201	RNA secondary structure unwinding
BWQ92_RS07115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BWQ92_RS07120	COG2364	Membrane
BWQ92_RS07125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWQ92_RS07140	COG0564	pseudouridine synthase activity
BWQ92_RS07150	COG0586	Pfam SNARE associated Golgi protein
BWQ92_RS07160	COG2801	Transposase and inactivated derivatives
BWQ92_RS07170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BWQ92_RS07205	COG3842	ATPase activity
BWQ92_RS07210	COG1621	beta-fructofuranosidase activity
BWQ92_RS07240	COG0343	queuine tRNA-ribosyltransferase activity
BWQ92_RS07255	COG0477	Major facilitator Superfamily
BWQ92_RS07260	COG0745	RESPONSE REGULATOR receiver
BWQ92_RS07265	COG2205	protein histidine kinase activity
BWQ92_RS07275	COG0351	phosphomethylpyrimidine kinase
BWQ92_RS07290	COG0028	Belongs to the TPP enzyme family
BWQ92_RS07300	COG1476	TRANSCRIPTIONal
BWQ92_RS07310	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BWQ92_RS07325	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS07330	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BWQ92_RS07345	COG1940	carbohydrate kinase activity
BWQ92_RS07355	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BWQ92_RS07385	COG1846	Transcriptional regulator
BWQ92_RS07385	COG1940	carbohydrate kinase activity
BWQ92_RS07390	COG0142	geranyltranstransferase activity
BWQ92_RS07395	COG1172	Belongs to the binding-protein-dependent transport system permease family
BWQ92_RS07400	COG1129	ABC transporter
BWQ92_RS07405	COG1879	ABC-type sugar transport system periplasmic component
BWQ92_RS07410	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS07425	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS07430	COG0438	transferase activity, transferring glycosyl groups
BWQ92_RS07465	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BWQ92_RS07470	COG0741	lytic transglycosylase activity
BWQ92_RS07470	COG0739	heme binding
BWQ92_RS07470	COG1196	nuclear chromosome segregation
BWQ92_RS07485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BWQ92_RS07500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BWQ92_RS07520	COG1404	Belongs to the peptidase S8 family
BWQ92_RS07555	COG0047	phosphoribosylformylglycinamidine synthase activity
BWQ92_RS07560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BWQ92_RS07585	COG4762	Protein conserved in bacteria
BWQ92_RS07590	COG2315	Protein conserved in bacteria
BWQ92_RS07600	COG1832	CoA-binding protein
BWQ92_RS07605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWQ92_RS07620	COG1832	CoA-binding protein
BWQ92_RS07640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BWQ92_RS07675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BWQ92_RS07685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BWQ92_RS07695	COG1414	Transcriptional regulator
BWQ92_RS07700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BWQ92_RS07710	COG0666	response to abiotic stimulus
BWQ92_RS07720	COG4585	Histidine kinase
BWQ92_RS07725	COG2197	response regulator
BWQ92_RS07740	COG1278	Cold shock
BWQ92_RS07745	COG2318	DinB family
BWQ92_RS07750	COG1960	acyl-CoA dehydrogenase activity
BWQ92_RS07755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWQ92_RS07800	COG1024	Enoyl-CoA hydratase
BWQ92_RS07820	COG1609	Transcriptional regulator
BWQ92_RS07845	COG0366	Alpha amylase catalytic
BWQ92_RS07870	COG1302	Protein conserved in bacteria
BWQ92_RS07900	COG0697	spore germination
BWQ92_RS07935	COG0586	Pfam SNARE associated Golgi protein
BWQ92_RS07940	COG0574	Belongs to the PEP-utilizing enzyme family
BWQ92_RS07940	COG3848	Pyruvate phosphate dikinase
BWQ92_RS07960	COG2252	PERMEase
BWQ92_RS07965	COG0010	Belongs to the arginase family
BWQ92_RS07970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWQ92_RS07995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BWQ92_RS08025	COG1280	lysine exporter protein (LysE YggA)
BWQ92_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS08035	COG0583	DNA-binding transcription factor activity
BWQ92_RS08045	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BWQ92_RS08045	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BWQ92_RS08050	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS08065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BWQ92_RS08065	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BWQ92_RS08070	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BWQ92_RS08075	COG0438	transferase activity, transferring glycosyl groups
BWQ92_RS08085	COG0859	PFAM glycosyl transferase family 9
BWQ92_RS08090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BWQ92_RS08100	COG1191	sigma factor activity
BWQ92_RS08140	COG0783	Belongs to the Dps family
BWQ92_RS08155	COG4122	O-methyltransferase activity
BWQ92_RS08195	COG2733	membrane
BWQ92_RS08200	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BWQ92_RS08225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWQ92_RS08240	COG1349	DNA-binding transcription factor activity
BWQ92_RS08245	COG1105	Belongs to the carbohydrate kinase PfkB family
BWQ92_RS08250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWQ92_RS08250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWQ92_RS08250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWQ92_RS08270	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BWQ92_RS08275	COG3285	dna ligase
BWQ92_RS08275	COG1793	dna ligase
BWQ92_RS08290	COG0477	Major facilitator Superfamily
BWQ92_RS08300	COG0300	oxidoreductase activity
BWQ92_RS08315	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BWQ92_RS08320	COG0076	glutamate decarboxylase activity
BWQ92_RS08350	COG2084	Dehydrogenase
BWQ92_RS08360	COG2186	Transcriptional regulator
BWQ92_RS08365	COG2801	Transposase and inactivated derivatives
BWQ92_RS08370	COG3360	Dodecin
BWQ92_RS08385	COG0656	L-ascorbic acid biosynthetic process
BWQ92_RS08390	COG0667	Aldo Keto reductase
BWQ92_RS08410	COG2261	transglycosylase associated protein
BWQ92_RS08425	COG2890	protein-(glutamine-N5) methyltransferase activity
BWQ92_RS08450	COG1621	beta-fructofuranosidase activity
BWQ92_RS08480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWQ92_RS08490	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BWQ92_RS08495	COG0829	nickel cation binding
BWQ92_RS08500	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BWQ92_RS08505	COG0830	nickel cation binding
BWQ92_RS08510	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BWQ92_RS08515	COG0804	urea catabolic process
BWQ92_RS08520	COG0832	Belongs to the urease beta subunit family
BWQ92_RS08525	COG0831	urea catabolic process
BWQ92_RS08535	COG1609	Transcriptional regulator
BWQ92_RS08540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BWQ92_RS08565	COG0306	phosphate transporter
BWQ92_RS08570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BWQ92_RS08610	COG3226	Transcriptional regulator
BWQ92_RS08620	COG4977	sequence-specific DNA binding
BWQ92_RS08625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BWQ92_RS08650	COG1802	Transcriptional regulator
BWQ92_RS08665	COG3971	2-oxopent-4-enoate hydratase activity
BWQ92_RS08680	COG0477	Major facilitator Superfamily
BWQ92_RS08705	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BWQ92_RS08710	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BWQ92_RS08735	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BWQ92_RS08735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BWQ92_RS08735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWQ92_RS08745	COG2376	Dihydroxyacetone kinase
BWQ92_RS08750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BWQ92_RS08755	COG1506	peptidase
BWQ92_RS08755	COG0823	Involved in the tonB-independent uptake of proteins
BWQ92_RS08775	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BWQ92_RS08790	COG2814	Major facilitator Superfamily
BWQ92_RS08795	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BWQ92_RS08825	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BWQ92_RS08830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BWQ92_RS08835	COG0302	gtp cyclohydrolase
BWQ92_RS08840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWQ92_RS08850	COG0037	tRNA processing
BWQ92_RS08860	COG2027	D-alanyl-D-alanine carboxypeptidase
BWQ92_RS08875	COG0561	phosphatase activity
BWQ92_RS08880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BWQ92_RS08885	COG1597	lipid kinase activity
BWQ92_RS08895	COG0077	Prephenate dehydratase
BWQ92_RS08900	COG0425	Belongs to the sulfur carrier protein TusA family
BWQ92_RS08900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWQ92_RS08905	COG0154	amidase activity
BWQ92_RS08925	COG0778	Nitroreductase
BWQ92_RS08930	COG2233	PERMEase
BWQ92_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS08950	COG1929	Belongs to the glycerate kinase type-1 family
BWQ92_RS08955	COG0028	Belongs to the TPP enzyme family
BWQ92_RS08970	COG0584	glycerophosphoryl diester phosphodiesterase
BWQ92_RS08985	COG5002	protein histidine kinase activity
BWQ92_RS08990	COG1609	Transcriptional regulator
BWQ92_RS08995	COG1653	transport
BWQ92_RS09000	COG1175	transmembrane transport
BWQ92_RS09010	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS09025	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS09035	COG1070	Carbohydrate kinase
BWQ92_RS09040	COG2115	Belongs to the xylose isomerase family
BWQ92_RS09045	COG0277	FAD linked oxidase domain protein
BWQ92_RS09060	COG0129	dihydroxy-acid dehydratase activity
BWQ92_RS09075	COG2814	Major facilitator Superfamily
BWQ92_RS09080	COG0456	acetyltransferase
BWQ92_RS09090	COG0697	spore germination
BWQ92_RS09105	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS09135	COG4213	ABC transporter substrate-binding protein
BWQ92_RS09140	COG1129	ABC transporter
BWQ92_RS09145	COG4214	carbohydrate transport
BWQ92_RS09150	COG1609	Transcriptional regulator
BWQ92_RS09155	COG2017	converts alpha-aldose to the beta-anomer
BWQ92_RS09160	COG2160	L-arabinose isomerase activity
BWQ92_RS09175	COG1609	Transcriptional regulator
BWQ92_RS09205	COG0765	amino acid transport
BWQ92_RS09220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWQ92_RS09230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWQ92_RS09235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWQ92_RS09255	COG1113	amino acid transport
BWQ92_RS09260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWQ92_RS09260	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWQ92_RS09265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BWQ92_RS09270	COG0509	glycine decarboxylation via glycine cleavage system
BWQ92_RS09280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BWQ92_RS09290	COG1250	3-hydroxyacyl-CoA dehydrogenase
BWQ92_RS09295	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS09300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BWQ92_RS09305	COG0477	Major facilitator Superfamily
BWQ92_RS09310	COG1609	Transcriptional regulator
BWQ92_RS09345	COG2188	Transcriptional regulator
BWQ92_RS09350	COG2814	Major facilitator Superfamily
BWQ92_RS09355	COG2971	BadF BadG BcrA BcrD
BWQ92_RS09360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BWQ92_RS09365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BWQ92_RS09385	COG1609	Transcriptional regulator
BWQ92_RS09390	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS09445	COG0659	secondary active sulfate transmembrane transporter activity
BWQ92_RS09455	COG3706	GGDEF domain
BWQ92_RS09460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWQ92_RS09465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWQ92_RS09475	COG1609	Transcriptional regulator
BWQ92_RS09485	COG0531	amino acid
BWQ92_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS09540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWQ92_RS09545	COG0069	glutamate synthase activity
BWQ92_RS09550	COG2218	PFAM glutamate synthase alpha subunit domain protein
BWQ92_RS09555	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BWQ92_RS09575	COG2801	Transposase and inactivated derivatives
BWQ92_RS09590	COG0387	Pfam Sodium calcium exchanger
BWQ92_RS09595	COG1846	Transcriptional regulator
BWQ92_RS09605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BWQ92_RS09645	COG0765	amino acid transport
BWQ92_RS09650	COG1126	abc transporter atp-binding protein
BWQ92_RS09655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWQ92_RS09660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWQ92_RS09665	COG3938	Belongs to the proline racemase family
BWQ92_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS09680	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS09685	COG3938	Belongs to the proline racemase family
BWQ92_RS09700	COG0698	ribose 5-phosphate isomerase
BWQ92_RS09705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BWQ92_RS09710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BWQ92_RS09720	COG2197	response regulator
BWQ92_RS09735	COG0475	glutathione-regulated potassium exporter activity
BWQ92_RS09795	COG0531	amino acid
BWQ92_RS09810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWQ92_RS09840	COG0406	alpha-ribazole phosphatase activity
BWQ92_RS09845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWQ92_RS09845	COG4499	WXG100 protein secretion system (Wss), protein YukC
BWQ92_RS09855	COG1349	DNA-binding transcription factor activity
BWQ92_RS09860	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS09870	COG3836	Belongs to the HpcH HpaI aldolase family
BWQ92_RS09875	COG0667	Aldo Keto reductase
BWQ92_RS09880	COG4608	Belongs to the ABC transporter superfamily
BWQ92_RS09885	COG0444	Belongs to the ABC transporter superfamily
BWQ92_RS09890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWQ92_RS09895	COG0601	transmembrane transport
BWQ92_RS09905	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BWQ92_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS09920	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BWQ92_RS09920	COG1796	DNA polymerase
BWQ92_RS09925	COG0346	lactoylglutathione lyase activity
BWQ92_RS09940	COG0679	Auxin Efflux Carrier
BWQ92_RS09945	COG2124	cytochrome p450
BWQ92_RS09960	COG4948	Mandelate Racemase Muconate Lactonizing
BWQ92_RS09965	COG1802	Transcriptional regulator
BWQ92_RS09970	COG2271	Major facilitator Superfamily
BWQ92_RS10035	COG0179	Fumarylacetoacetate (FAA) hydrolase
BWQ92_RS10040	COG0179	Fumarylacetoacetate (FAA) hydrolase
BWQ92_RS10045	COG2188	Transcriptional regulator
BWQ92_RS10050	COG1024	Enoyl-CoA hydratase
BWQ92_RS10060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWQ92_RS10065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWQ92_RS10090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWQ92_RS10095	COG4670	ketone body catabolic process
BWQ92_RS10105	COG2030	dehydratase
BWQ92_RS10105	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS10110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWQ92_RS10135	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS10140	COG1126	abc transporter atp-binding protein
BWQ92_RS10145	COG0765	amino acid transport
BWQ92_RS10155	COG1609	Transcriptional regulator
BWQ92_RS10165	COG0589	response to stress
BWQ92_RS10185	COG0583	DNA-binding transcription factor activity
BWQ92_RS10190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWQ92_RS10200	COG4948	Mandelate Racemase Muconate Lactonizing
BWQ92_RS10215	COG1609	Transcriptional regulator
BWQ92_RS10240	COG1716	ATPase activity
BWQ92_RS10255	COG0768	penicillin binding
BWQ92_RS10260	COG0515	serine threonine protein kinase
BWQ92_RS10265	COG0515	serine threonine protein kinase
BWQ92_RS10270	COG0024	Methionine aminopeptidase
BWQ92_RS10280	COG3764	Sortase (surface protein transpeptidase)
BWQ92_RS10290	COG2818	Glycosylase
BWQ92_RS10295	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BWQ92_RS10300	COG0705	Rhomboid family
BWQ92_RS10315	COG1215	transferase activity, transferring glycosyl groups
BWQ92_RS10335	COG3266	domain, Protein
BWQ92_RS10345	COG0187	DNA topoisomerase II activity
BWQ92_RS10350	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
BWQ92_RS10355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BWQ92_RS10360	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BWQ92_RS10365	COG0592	DNA-directed DNA polymerase activity
BWQ92_RS10370	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BWQ92_RS10375	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BWQ92_RS10380	COG0594	ribonuclease P activity
BWQ92_RS10385	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BWQ92_RS10390	COG0706	membrane insertase activity
BWQ92_RS10400	COG0357	Ribosomal RNA small subunit methyltransferase G
BWQ92_RS10405	COG1192	Involved in chromosome partitioning
BWQ92_RS10415	COG3118	belongs to the thioredoxin family
BWQ92_RS10420	COG0492	ferredoxin-NADP+ reductase activity
BWQ92_RS10440	COG0617	tRNA 3'-terminal CCA addition
BWQ92_RS10445	COG0406	alpha-ribazole phosphatase activity
BWQ92_RS10470	COG0738	Major facilitator superfamily
BWQ92_RS10480	COG1131	(ABC) transporter
BWQ92_RS10490	COG4585	Histidine kinase
BWQ92_RS10495	COG2197	response regulator
BWQ92_RS10505	COG1362	aminopeptidase activity
BWQ92_RS10510	COG1113	amino acid transport
BWQ92_RS10515	COG1742	UPF0060 membrane protein
BWQ92_RS10525	COG0360	Binds together with S18 to 16S ribosomal RNA
BWQ92_RS10535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BWQ92_RS10540	COG0359	binds to the 23S rRNA
BWQ92_RS10575	COG0305	Participates in initiation and elongation during chromosome replication
BWQ92_RS10585	COG2259	Doxx family
BWQ92_RS10590	COG0534	Mate efflux family protein
BWQ92_RS10610	COG0697	spore germination
BWQ92_RS10635	COG1937	Protein conserved in bacteria
BWQ92_RS10665	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BWQ92_RS10675	COG0179	Fumarylacetoacetate (FAA) hydrolase
BWQ92_RS10680	COG3971	2-oxopent-4-enoate hydratase activity
BWQ92_RS10715	COG0477	Major facilitator Superfamily
BWQ92_RS10740	COG0366	Alpha amylase catalytic
BWQ92_RS10755	COG1793	dna ligase
BWQ92_RS10765	COG1414	Transcriptional regulator
BWQ92_RS10770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BWQ92_RS10780	COG3485	protocatechuate 3,4-dioxygenase
BWQ92_RS10785	COG3485	protocatechuate 3,4-dioxygenase
BWQ92_RS10790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BWQ92_RS10800	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BWQ92_RS10805	COG0183	Belongs to the thiolase family
BWQ92_RS10815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BWQ92_RS10820	COG1414	Transcriptional regulator
BWQ92_RS10835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWQ92_RS10840	COG0477	Major facilitator Superfamily
BWQ92_RS10850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BWQ92_RS10855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWQ92_RS10880	COG3415	Transposase
BWQ92_RS10880	COG2801	Transposase and inactivated derivatives
BWQ92_RS10885	COG0583	DNA-binding transcription factor activity
BWQ92_RS10895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWQ92_RS10900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWQ92_RS10910	COG1597	lipid kinase activity
BWQ92_RS10920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BWQ92_RS10930	COG1802	Transcriptional regulator
BWQ92_RS10935	COG2271	Major facilitator Superfamily
BWQ92_RS10940	COG0667	Aldo Keto reductase
BWQ92_RS10960	COG2814	Major facilitator Superfamily
BWQ92_RS10980	COG1607	acyl-coa hydrolase
BWQ92_RS10990	COG2902	Dehydrogenase
BWQ92_RS10995	COG0406	alpha-ribazole phosphatase activity
BWQ92_RS11000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BWQ92_RS11015	COG1950	PFAM Membrane protein of
BWQ92_RS11020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BWQ92_RS11030	COG0022	dehydrogenase e1 component
BWQ92_RS11035	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWQ92_RS11055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWQ92_RS11070	COG0431	NADPH-dependent FMN reductase
BWQ92_RS11080	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS11085	COG0686	Belongs to the AlaDH PNT family
BWQ92_RS11120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BWQ92_RS11130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWQ92_RS11130	COG2213	PTS system mannitol-specific
BWQ92_RS11135	COG0246	Mannitol dehydrogenase
BWQ92_RS11140	COG0702	epimerase
BWQ92_RS11145	COG1733	regulation of RNA biosynthetic process
BWQ92_RS11150	COG0477	Major facilitator Superfamily
BWQ92_RS11155	COG0477	Major facilitator Superfamily
BWQ92_RS11200	COG1280	lysine exporter protein (LysE YggA)
BWQ92_RS11205	COG1522	sequence-specific DNA binding
BWQ92_RS11220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BWQ92_RS11230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWQ92_RS11240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWQ92_RS11240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWQ92_RS11265	COG2186	Transcriptional regulator
BWQ92_RS11270	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BWQ92_RS11275	COG3093	addiction module antidote protein HigA
BWQ92_RS11285	COG1715	Restriction endonuclease
BWQ92_RS11335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BWQ92_RS11340	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BWQ92_RS11360	COG3958	Transketolase
BWQ92_RS11365	COG3959	Transketolase, thiamine diphosphate binding domain
BWQ92_RS11380	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS11385	COG2376	Dihydroxyacetone kinase
BWQ92_RS11390	COG0698	ribose 5-phosphate isomerase
BWQ92_RS11405	COG0667	Aldo Keto reductase
BWQ92_RS11415	COG3012	SEC-C Motif Domain Protein
BWQ92_RS11470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWQ92_RS11475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWQ92_RS11480	COG1120	ATPase activity
BWQ92_RS11495	COG3415	Transposase
BWQ92_RS11495	COG2801	Transposase and inactivated derivatives
BWQ92_RS11515	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BWQ92_RS11520	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BWQ92_RS11525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BWQ92_RS11600	COG0776	regulation of translation
BWQ92_RS11605	COG3336	cytochrome c oxidase
BWQ92_RS11620	COG0433	COG0433 Predicted ATPase
BWQ92_RS11625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWQ92_RS11630	COG3387	PFAM Glycoside hydrolase 15-related
BWQ92_RS11645	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BWQ92_RS11655	COG0531	amino acid
BWQ92_RS11660	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS11670	COG0583	DNA-binding transcription factor activity
BWQ92_RS11690	COG0717	Belongs to the dCTP deaminase family
BWQ92_RS11695	COG0475	glutathione-regulated potassium exporter activity
BWQ92_RS11710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BWQ92_RS11710	COG2111	Na H antiporter
BWQ92_RS11715	COG1006	Multisubunit Na H antiporter MnhC subunit
BWQ92_RS11720	COG0651	ATP synthesis coupled electron transport
BWQ92_RS11730	COG2212	antiporter activity
BWQ92_RS11735	COG1320	monovalent cation:proton antiporter activity
BWQ92_RS11750	COG4702	Belongs to the UPF0303 family
BWQ92_RS11755	COG4721	ABC-type cobalt transport system, permease component
BWQ92_RS11760	COG1122	ATPase activity
BWQ92_RS11780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BWQ92_RS11785	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BWQ92_RS11795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWQ92_RS11830	COG2986	histidine ammonia-lyase
BWQ92_RS11840	COG2199	diguanylate cyclase activity
BWQ92_RS11840	COG2200	EAL domain
BWQ92_RS11850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWQ92_RS11860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BWQ92_RS11865	COG1280	lysine exporter protein (LysE YggA)
BWQ92_RS11880	COG2409	Drug exporters of the RND superfamily
BWQ92_RS11900	COG0443	Heat shock 70 kDa protein
BWQ92_RS11905	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BWQ92_RS11910	COG0484	heat shock protein binding
BWQ92_RS11915	COG0789	Transcriptional regulator
BWQ92_RS11920	COG3848	Pyruvate phosphate dikinase
BWQ92_RS11920	COG0574	Belongs to the PEP-utilizing enzyme family
BWQ92_RS11935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BWQ92_RS11940	COG0589	response to stress
BWQ92_RS11960	COG3290	protein histidine kinase activity
BWQ92_RS11970	COG0563	adenylate kinase activity
BWQ92_RS11975	COG4941	Belongs to the sigma-70 factor family
BWQ92_RS11995	COG3135	benzoate transporter
BWQ92_RS12010	COG2186	Transcriptional regulator
BWQ92_RS12020	COG2376	Dihydroxyacetone kinase
BWQ92_RS12025	COG0698	ribose 5-phosphate isomerase
BWQ92_RS12030	COG0149	triose-phosphate isomerase activity
BWQ92_RS12035	COG1082	Xylose isomerase domain protein TIM barrel
BWQ92_RS12040	COG2084	Dehydrogenase
BWQ92_RS12045	COG0659	secondary active sulfate transmembrane transporter activity
BWQ92_RS12070	COG0477	Major facilitator Superfamily
BWQ92_RS12075	COG2186	Transcriptional regulator
BWQ92_RS12090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BWQ92_RS12125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BWQ92_RS12140	COG2807	transmembrane transport
BWQ92_RS12145	COG0477	Major facilitator Superfamily
BWQ92_RS12150	COG1473	amidohydrolase
BWQ92_RS12175	COG1113	amino acid transport
BWQ92_RS12190	COG2076	Multidrug Resistance protein
BWQ92_RS12200	COG1528	Iron-storage protein
BWQ92_RS12210	COG0135	phosphoribosylanthranilate isomerase activity
BWQ92_RS12220	COG3304	Inner membrane component domain
BWQ92_RS12275	COG0542	response to heat
BWQ92_RS12295	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BWQ92_RS12315	COG2351	hydroxyisourate hydrolase activity
BWQ92_RS12330	COG5002	protein histidine kinase activity
BWQ92_RS12340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWQ92_RS12355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWQ92_RS12360	COG4948	Mandelate Racemase Muconate Lactonizing
BWQ92_RS12370	COG0129	dihydroxy-acid dehydratase activity
BWQ92_RS12440	COG1253	flavin adenine dinucleotide binding
BWQ92_RS12445	COG1271	oxidase subunit
BWQ92_RS12455	COG3795	YCII-related domain
BWQ92_RS12520	COG0492	ferredoxin-NADP+ reductase activity
BWQ92_RS12530	COG0646	methionine synthase
BWQ92_RS12530	COG1410	methionine synthase
BWQ92_RS12535	COG3845	ABC transporter
BWQ92_RS12550	COG3415	Transposase
BWQ92_RS12550	COG2801	Transposase and inactivated derivatives
BWQ92_RS12570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWQ92_RS12590	COG1414	Transcriptional regulator
BWQ92_RS12600	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BWQ92_RS12605	COG3415	Transposase
BWQ92_RS12605	COG2801	Transposase and inactivated derivatives
BWQ92_RS12625	COG3404	Formiminotransferase-cyclodeaminase
BWQ92_RS12645	COG0477	Major facilitator Superfamily
BWQ92_RS12670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWQ92_RS12705	COG2199	diguanylate cyclase activity
BWQ92_RS12705	COG2200	EAL domain
BWQ92_RS12715	COG2149	membrane
BWQ92_RS12720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BWQ92_RS12725	COG3119	arylsulfatase activity
BWQ92_RS12730	COG2271	Major facilitator Superfamily
BWQ92_RS12750	COG1802	Transcriptional regulator
BWQ92_RS12755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BWQ92_RS12780	COG1760	l-serine dehydratase
BWQ92_RS12800	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BWQ92_RS12805	COG1929	Belongs to the glycerate kinase type-1 family
BWQ92_RS12810	COG3960	tartronate-semialdehyde synthase activity
BWQ92_RS12815	COG2084	Dehydrogenase
BWQ92_RS12820	COG3622	Belongs to the hyi family
BWQ92_RS12840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BWQ92_RS12845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BWQ92_RS12855	COG0384	phenazine biosynthesis protein PhzF
BWQ92_RS12890	COG0833	amino acid
BWQ92_RS12910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWQ92_RS12920	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS12925	COG0596	Alpha beta hydrolase
BWQ92_RS12940	COG1802	Transcriptional regulator
BWQ92_RS12950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWQ92_RS12965	COG0028	Belongs to the TPP enzyme family
BWQ92_RS12970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BWQ92_RS12975	COG1113	amino acid transport
BWQ92_RS12990	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BWQ92_RS13030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BWQ92_RS13065	COG2326	polyphosphate kinase activity
BWQ92_RS13085	COG1175	transmembrane transport
BWQ92_RS13090	COG0395	ABC-type sugar transport system, permease component
BWQ92_RS13105	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS13110	COG1802	Transcriptional regulator
BWQ92_RS13115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BWQ92_RS13130	COG2154	pterin-4-alpha-carbinolamine dehydratase
BWQ92_RS13140	COG1609	Transcriptional regulator
BWQ92_RS13150	COG1175	transmembrane transport
BWQ92_RS13155	COG0395	ABC-type sugar transport system, permease component
BWQ92_RS13170	COG3226	Transcriptional regulator
BWQ92_RS13225	COG3585	molybdate ion transport
BWQ92_RS13270	COG0436	Aminotransferase
BWQ92_RS13275	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BWQ92_RS13295	COG4948	Mandelate Racemase Muconate Lactonizing
BWQ92_RS13305	COG0583	DNA-binding transcription factor activity
BWQ92_RS13310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BWQ92_RS13315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BWQ92_RS13325	COG0477	Major facilitator Superfamily
BWQ92_RS13330	COG4221	oxidoreductase activity
BWQ92_RS13340	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS13350	COG3265	gluconokinase activity
BWQ92_RS13370	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS13380	COG1737	Transcriptional regulator
BWQ92_RS13410	COG0477	Major facilitator Superfamily
BWQ92_RS13415	COG1063	alcohol dehydrogenase
BWQ92_RS13420	COG0246	Mannitol dehydrogenase
BWQ92_RS13425	COG4948	Mandelate Racemase Muconate Lactonizing
BWQ92_RS13430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BWQ92_RS13435	COG1609	Transcriptional regulator
BWQ92_RS13440	COG1053	succinate dehydrogenase
BWQ92_RS13445	COG1063	alcohol dehydrogenase
BWQ92_RS13455	COG0583	DNA-binding transcription factor activity
BWQ92_RS13460	COG0477	Major facilitator Superfamily
BWQ92_RS13465	COG1414	Transcriptional regulator
BWQ92_RS13475	COG0477	Major facilitator Superfamily
BWQ92_RS13480	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS13485	COG1902	pentaerythritol trinitrate reductase activity
BWQ92_RS13485	COG0446	pyridine nucleotide-disulphide oxidoreductase
BWQ92_RS13500	COG1053	succinate dehydrogenase
BWQ92_RS13520	COG4770	biotin carboxylase activity
BWQ92_RS13525	COG1984	allophanate hydrolase subunit 2
BWQ92_RS13530	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BWQ92_RS13535	COG2186	Transcriptional regulator
BWQ92_RS13545	COG4336	lyase activity
BWQ92_RS13585	COG3118	belongs to the thioredoxin family
BWQ92_RS13610	COG1132	(ABC) transporter
BWQ92_RS13650	COG2186	Transcriptional regulator
BWQ92_RS13660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWQ92_RS13660	COG1017	nitric oxide dioxygenase activity
BWQ92_RS13670	COG0598	Magnesium transport protein CorA
BWQ92_RS13685	COG2267	carboxylic ester hydrolase activity
BWQ92_RS13690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWQ92_RS13700	COG1072	(Pantothenic acid kinase))
BWQ92_RS13705	COG2203	Gaf domain
BWQ92_RS13705	COG4585	Histidine kinase
BWQ92_RS13740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWQ92_RS13775	COG0484	heat shock protein binding
BWQ92_RS13785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWQ92_RS13815	COG3387	PFAM Glycoside hydrolase 15-related
BWQ92_RS13825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWQ92_RS13845	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS13855	COG3257	ureidoglycine aminohydrolase activity
BWQ92_RS13865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BWQ92_RS13875	COG1414	Transcriptional regulator
BWQ92_RS13880	COG2233	PERMEase
BWQ92_RS13890	COG1793	dna ligase
BWQ92_RS13890	COG3285	dna ligase
BWQ92_RS13900	COG0590	tRNA wobble adenosine to inosine editing
BWQ92_RS13905	COG2252	PERMEase
BWQ92_RS13910	COG3608	succinylglutamate desuccinylase aspartoacylase
BWQ92_RS13910	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BWQ92_RS13920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BWQ92_RS13925	COG0667	Aldo Keto reductase
BWQ92_RS13950	COG1953	Uracil, thiamine, allantoin
BWQ92_RS13960	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS13970	COG1301	dicarboxylic acid transport
BWQ92_RS13990	COG0151	Belongs to the GarS family
BWQ92_RS13995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BWQ92_RS14020	COG1132	(ABC) transporter
BWQ92_RS14025	COG1132	(ABC) transporter
BWQ92_RS14030	COG1408	metallophosphoesterase
BWQ92_RS14035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWQ92_RS14075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWQ92_RS14090	COG0395	ABC-type sugar transport system, permease component
BWQ92_RS14105	COG1609	Transcriptional regulator
BWQ92_RS14110	COG1349	DNA-binding transcription factor activity
BWQ92_RS14115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWQ92_RS14130	COG1051	belongs to the nudix hydrolase family
BWQ92_RS14180	COG1111	helicase
BWQ92_RS14180	COG1205	dead DEAH box helicase
BWQ92_RS14190	COG1054	Belongs to the UPF0176 family
BWQ92_RS14210	COG2890	protein-(glutamine-N5) methyltransferase activity
BWQ92_RS14225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWQ92_RS14225	COG1754	DNA topoisomerase type I activity
BWQ92_RS14235	COG0248	Ppx GppA phosphatase
BWQ92_RS14240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BWQ92_RS14245	COG0569	domain protein
BWQ92_RS14250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWQ92_RS14255	COG0123	including yeast histone deacetylase and acetoin utilization protein
BWQ92_RS14260	COG0640	Transcriptional regulator
BWQ92_RS14270	COG2186	Transcriptional regulator
BWQ92_RS14280	COG1609	Transcriptional regulator
BWQ92_RS14285	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS14295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWQ92_RS14300	COG4948	Mandelate Racemase Muconate Lactonizing
BWQ92_RS14315	COG1175	transmembrane transport
BWQ92_RS14320	COG0395	ABC-type sugar transport system, permease component
BWQ92_RS14345	COG3254	rhamnose metabolic process
BWQ92_RS14350	COG4952	isomerase
BWQ92_RS14355	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS14355	COG3347	Dehydrogenase
BWQ92_RS14360	COG1070	Carbohydrate kinase
BWQ92_RS14365	COG3458	cephalosporin-C deacetylase activity
BWQ92_RS14370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWQ92_RS14395	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BWQ92_RS14405	COG2353	YceI-like domain
BWQ92_RS14410	COG0406	alpha-ribazole phosphatase activity
BWQ92_RS14415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWQ92_RS14420	COG0785	Cytochrome C biogenesis protein
BWQ92_RS14430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWQ92_RS14460	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BWQ92_RS14470	COG1266	CAAX protease self-immunity
BWQ92_RS14475	COG0803	Belongs to the bacterial solute-binding protein 9 family
BWQ92_RS14480	COG1121	(ABC) transporter
BWQ92_RS14485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BWQ92_RS14490	COG0488	(ABC) transporter
BWQ92_RS14525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BWQ92_RS14530	COG2390	Transcriptional regulator
BWQ92_RS14535	COG1063	alcohol dehydrogenase
BWQ92_RS14540	COG2814	Major facilitator Superfamily
BWQ92_RS14545	COG2376	Dihydroxyacetone kinase
BWQ92_RS14550	COG0698	ribose 5-phosphate isomerase
BWQ92_RS14555	COG0183	Belongs to the thiolase family
BWQ92_RS14560	COG1024	Enoyl-CoA hydratase
BWQ92_RS14565	COG1250	3-hydroxyacyl-CoA dehydrogenase
BWQ92_RS14605	COG0390	transport system, permease component
BWQ92_RS14610	COG2050	protein possibly involved in aromatic compounds catabolism
BWQ92_RS14615	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS14615	COG2030	dehydratase
BWQ92_RS14635	COG2132	Multicopper oxidase
BWQ92_RS14645	COG2050	protein possibly involved in aromatic compounds catabolism
BWQ92_RS14660	COG0857	belongs to the CobB CobQ family
BWQ92_RS14660	COG0280	phosphate acetyltransferase
BWQ92_RS14665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BWQ92_RS14685	COG5002	protein histidine kinase activity
BWQ92_RS14720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BWQ92_RS14755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BWQ92_RS14765	COG1316	TRANSCRIPTIONal
BWQ92_RS14770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BWQ92_RS14845	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BWQ92_RS14870	COG0745	RESPONSE REGULATOR receiver
BWQ92_RS14900	COG2814	Major facilitator Superfamily
BWQ92_RS14905	COG1609	Transcriptional regulator
BWQ92_RS14915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BWQ92_RS14920	COG0492	ferredoxin-NADP+ reductase activity
BWQ92_RS14925	COG1064	alcohol dehydrogenase
BWQ92_RS14960	COG1476	TRANSCRIPTIONal
BWQ92_RS14965	COG3634	alkyl hydroperoxide reductase activity
BWQ92_RS14995	COG2217	Heavy metal translocating P-type atpase
BWQ92_RS15010	COG1914	H( )-stimulated, divalent metal cation uptake system
BWQ92_RS15015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWQ92_RS15020	COG1609	Transcriptional regulator
BWQ92_RS15045	COG2149	membrane
BWQ92_RS15075	COG0277	FAD linked oxidase domain protein
BWQ92_RS15085	COG1846	Transcriptional regulator
BWQ92_RS15090	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BWQ92_RS15135	COG2249	NAD(P)H dehydrogenase (quinone) activity
BWQ92_RS15145	COG1027	Aspartate ammonia-lyase
BWQ92_RS15150	COG0477	Major facilitator Superfamily
BWQ92_RS15160	COG2608	mercury ion transmembrane transporter activity
BWQ92_RS15200	COG2755	lipolytic protein G-D-S-L family
BWQ92_RS15200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BWQ92_RS15205	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BWQ92_RS15210	COG1088	dTDP-glucose 4,6-dehydratase activity
BWQ92_RS15220	COG3396	Phenylacetate-CoA oxygenase
BWQ92_RS15225	COG3460	Phenylacetate-CoA oxygenase
BWQ92_RS15230	COG3396	Phenylacetate-CoA oxygenase
BWQ92_RS15235	COG2151	metal-sulfur cluster biosynthetic enzyme
BWQ92_RS15240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWQ92_RS15245	COG1024	Enoyl-CoA hydratase
BWQ92_RS15255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BWQ92_RS15285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BWQ92_RS15290	COG0489	protein tyrosine kinase activity
BWQ92_RS15325	COG0022	dehydrogenase e1 component
BWQ92_RS15330	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWQ92_RS15365	COG1404	Belongs to the peptidase S8 family
BWQ92_RS15370	COG1953	Uracil, thiamine, allantoin
BWQ92_RS15385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWQ92_RS15395	COG1280	lysine exporter protein (LysE YggA)
BWQ92_RS15405	COG2814	Major facilitator Superfamily
BWQ92_RS15435	COG1053	succinate dehydrogenase
BWQ92_RS15440	COG1802	Transcriptional regulator
BWQ92_RS15450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWQ92_RS15460	COG3655	Transcriptional regulator
BWQ92_RS15470	COG0640	Transcriptional regulator
BWQ92_RS15480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BWQ92_RS15495	COG2124	cytochrome p450
BWQ92_RS15495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BWQ92_RS15500	COG0739	heme binding
BWQ92_RS15500	COG0741	lytic transglycosylase activity
BWQ92_RS15500	COG1196	nuclear chromosome segregation
BWQ92_RS15505	COG4172	Belongs to the ABC transporter superfamily
BWQ92_RS15535	COG0477	Major facilitator Superfamily
BWQ92_RS15560	COG0765	amino acid transport
BWQ92_RS15565	COG0765	amino acid transport
BWQ92_RS15575	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS15580	COG0531	amino acid
BWQ92_RS15630	COG0569	domain protein
BWQ92_RS15635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWQ92_RS15675	COG0601	transmembrane transport
BWQ92_RS15680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWQ92_RS15685	COG4172	Belongs to the ABC transporter superfamily
BWQ92_RS15705	COG0436	Aminotransferase
BWQ92_RS15740	COG5002	protein histidine kinase activity
BWQ92_RS15750	COG4585	Histidine kinase
BWQ92_RS15755	COG4948	Mandelate Racemase Muconate Lactonizing
BWQ92_RS15765	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BWQ92_RS15780	COG0765	amino acid transport
BWQ92_RS15785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWQ92_RS15790	COG1169	isochorismate synthase
BWQ92_RS15795	COG2226	methyltransferase
BWQ92_RS15805	COG0142	geranyltranstransferase activity
BWQ92_RS15820	COG2860	membrane
BWQ92_RS15830	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWQ92_RS15835	COG0175	sulfate reduction
BWQ92_RS15845	COG2895	sulfate adenylyltransferase (ATP) activity
BWQ92_RS15855	COG1690	Belongs to the RtcB family
BWQ92_RS15865	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BWQ92_RS15870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWQ92_RS15875	COG1648	precorrin-2 dehydrogenase activity
BWQ92_RS15875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BWQ92_RS15910	COG2186	Transcriptional regulator
BWQ92_RS15925	COG0574	Belongs to the PEP-utilizing enzyme family
BWQ92_RS15925	COG3848	Pyruvate phosphate dikinase
BWQ92_RS15945	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS16010	COG0531	amino acid
BWQ92_RS16045	COG0501	Belongs to the peptidase M48B family
BWQ92_RS16050	COG0456	acetyltransferase
BWQ92_RS16055	COG1666	GTP binding
BWQ92_RS16070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BWQ92_RS16075	COG1388	LysM domain
BWQ92_RS16075	COG3942	CHAP domain
BWQ92_RS16080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWQ92_RS16090	COG0318	PFAM AMP-dependent synthetase and ligase
BWQ92_RS16115	COG5650	phosphatidylinositol metabolic process
BWQ92_RS16130	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS16140	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS16170	COG0754	glutathionylspermidine amidase activity
BWQ92_RS16215	COG1940	carbohydrate kinase activity
BWQ92_RS16225	COG1175	transmembrane transport
BWQ92_RS16230	COG0395	ABC-type sugar transport system, permease component
BWQ92_RS16235	COG0366	Alpha amylase catalytic
BWQ92_RS16240	COG4989	oxidoreductase activity
BWQ92_RS16270	COG2030	dehydratase
BWQ92_RS16280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BWQ92_RS16290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BWQ92_RS16315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BWQ92_RS16320	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BWQ92_RS16330	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BWQ92_RS16335	COG0456	acetyltransferase
BWQ92_RS16340	COG0745	RESPONSE REGULATOR receiver
BWQ92_RS16350	COG3485	protocatechuate 3,4-dioxygenase
BWQ92_RS16360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BWQ92_RS16405	COG2197	response regulator
BWQ92_RS16410	COG0436	Aminotransferase
BWQ92_RS16420	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWQ92_RS16430	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BWQ92_RS16435	COG0081	regulation of translation
BWQ92_RS16450	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BWQ92_RS16455	COG0222	ribosome binding
BWQ92_RS16460	COG0442	prolyl-tRNA aminoacylation
BWQ92_RS16465	COG0183	Belongs to the thiolase family
BWQ92_RS16470	COG0085	RNA polymerase activity
BWQ92_RS16475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BWQ92_RS16480	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BWQ92_RS16485	COG0049	tRNA binding
BWQ92_RS16490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWQ92_RS16495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BWQ92_RS16505	COG0051	transcription antitermination factor activity, RNA binding
BWQ92_RS16510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BWQ92_RS16515	COG0088	Forms part of the polypeptide exit tunnel
BWQ92_RS16520	COG0089	rRNA binding
BWQ92_RS16525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BWQ92_RS16530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BWQ92_RS16535	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BWQ92_RS16540	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BWQ92_RS16545	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BWQ92_RS16550	COG0255	Belongs to the universal ribosomal protein uL29 family
BWQ92_RS16555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BWQ92_RS16560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BWQ92_RS16565	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BWQ92_RS16570	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BWQ92_RS16575	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BWQ92_RS16580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BWQ92_RS16590	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BWQ92_RS16595	COG1841	ribosomal large subunit assembly
BWQ92_RS16600	COG0200	Binds to the 23S rRNA
BWQ92_RS16610	COG0563	adenylate kinase activity
BWQ92_RS16620	COG3191	aminopeptidase activity
BWQ92_RS16625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BWQ92_RS16630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BWQ92_RS16635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BWQ92_RS16640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BWQ92_RS16645	COG0202	RNA polymerase activity
BWQ92_RS16650	COG0203	ribosomal protein L17
BWQ92_RS16655	COG0101	tRNA pseudouridine synthase activity
BWQ92_RS16660	COG0745	RESPONSE REGULATOR receiver
BWQ92_RS16675	COG5002	protein histidine kinase activity
BWQ92_RS16680	COG0745	RESPONSE REGULATOR receiver
BWQ92_RS16705	COG2894	cell division
BWQ92_RS16745	COG2894	cell division
BWQ92_RS16780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BWQ92_RS16785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BWQ92_RS16790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWQ92_RS16795	COG1970	mechanosensitive ion channel activity
BWQ92_RS16800	COG1876	peptidase activity
BWQ92_RS16805	COG1072	(Pantothenic acid kinase))
BWQ92_RS16820	COG0736	holo-[acyl-carrier-protein] synthase activity
BWQ92_RS16845	COG0667	Aldo Keto reductase
BWQ92_RS16870	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BWQ92_RS16875	COG0438	transferase activity, transferring glycosyl groups
BWQ92_RS16880	COG1486	melibiose metabolic process
BWQ92_RS16890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BWQ92_RS16895	COG0802	atpase or kinase
BWQ92_RS16910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BWQ92_RS16915	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BWQ92_RS16920	COG1472	Belongs to the glycosyl hydrolase 3 family
BWQ92_RS16925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BWQ92_RS16940	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BWQ92_RS16945	COG0459	protein refolding
BWQ92_RS16955	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BWQ92_RS16955	COG2755	lipolytic protein G-D-S-L family
BWQ92_RS16985	COG0516	GMP reductase activity
BWQ92_RS16990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BWQ92_RS17010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BWQ92_RS17010	COG0519	Catalyzes the synthesis of GMP from XMP
BWQ92_RS17035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BWQ92_RS17040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BWQ92_RS17070	COG2354	Protein conserved in bacteria
BWQ92_RS17095	COG0598	Magnesium transport protein CorA
BWQ92_RS17130	COG2814	Major facilitator Superfamily
BWQ92_RS17135	COG0583	DNA-binding transcription factor activity
BWQ92_RS17155	COG2971	BadF BadG BcrA BcrD
BWQ92_RS17165	COG1162	GTPase activity
BWQ92_RS17175	COG1174	glycine betaine transport
BWQ92_RS17195	COG2326	polyphosphate kinase activity
BWQ92_RS17200	COG1722	exodeoxyribonuclease VII activity
BWQ92_RS17205	COG1570	exodeoxyribonuclease VII activity
BWQ92_RS17215	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BWQ92_RS17220	COG1322	Protein conserved in bacteria
BWQ92_RS17225	COG0012	GTP binding
BWQ92_RS17235	COG3383	formate dehydrogenase (NAD+) activity
BWQ92_RS17235	COG0243	molybdopterin cofactor binding
BWQ92_RS17245	COG0437	4 iron, 4 sulfur cluster binding
BWQ92_RS17255	COG0709	Synthesizes selenophosphate from selenide and ATP
BWQ92_RS17275	COG4166	transmembrane transport
BWQ92_RS17285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWQ92_RS17295	COG4172	Belongs to the ABC transporter superfamily
BWQ92_RS17305	COG1217	gtp-binding protein TYPA
BWQ92_RS17345	COG3226	Transcriptional regulator
BWQ92_RS17360	COG2171	N-acyltransferase activity
BWQ92_RS17365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWQ92_RS17370	COG0765	amino acid transport
BWQ92_RS17375	COG0765	amino acid transport
BWQ92_RS17380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWQ92_RS17385	COG1126	abc transporter atp-binding protein
BWQ92_RS17390	COG1611	Belongs to the LOG family
BWQ92_RS17415	COG1595	DNA-templated transcription, initiation
BWQ92_RS17425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BWQ92_RS17440	COG2239	Acts as a magnesium transporter
BWQ92_RS17450	COG0006	proline dipeptidase activity
BWQ92_RS17460	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BWQ92_RS17465	COG0513	Belongs to the DEAD box helicase family
BWQ92_RS17470	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BWQ92_RS17480	COG0352	thiamine-phosphate diphosphorylase activity
BWQ92_RS17485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWQ92_RS17485	COG2022	thiamine diphosphate biosynthetic process
BWQ92_RS17495	COG2022	thiamine diphosphate biosynthetic process
BWQ92_RS17500	COG2154	pterin-4-alpha-carbinolamine dehydratase
BWQ92_RS17530	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BWQ92_RS17535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BWQ92_RS17555	COG3253	May function as heme-dependent peroxidase
BWQ92_RS17560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BWQ92_RS17565	COG0181	hydroxymethylbilane synthase activity
BWQ92_RS17575	COG0113	porphobilinogen synthase activity
BWQ92_RS17580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWQ92_RS17585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BWQ92_RS17590	COG1464	Belongs to the NlpA lipoprotein family
BWQ92_RS17595	COG2011	ABC-type metal ion transport system permease component
BWQ92_RS17630	COG2816	NAD+ diphosphatase activity
BWQ92_RS17655	COG1615	UPF0182 protein
BWQ92_RS17675	COG0415	Belongs to the DNA photolyase family
BWQ92_RS17680	COG1842	Phage shock protein A
BWQ92_RS17690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWQ92_RS17695	COG2086	electron transfer activity
BWQ92_RS17700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BWQ92_RS17705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BWQ92_RS17720	COG1595	DNA-templated transcription, initiation
BWQ92_RS17725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BWQ92_RS17730	COG0484	heat shock protein binding
BWQ92_RS17760	COG0482	sulfurtransferase activity
BWQ92_RS17770	COG0601	transmembrane transport
BWQ92_RS17810	COG0714	Associated with various cellular activities
BWQ92_RS17835	COG5000	phosphorelay sensor kinase activity
BWQ92_RS17835	COG5002	protein histidine kinase activity
BWQ92_RS17840	COG5401	PFAM Sporulation and spore germination
BWQ92_RS17850	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BWQ92_RS17855	COG3214	Protein conserved in bacteria
BWQ92_RS17860	COG0653	protein targeting
BWQ92_RS17895	COG2902	Dehydrogenase
BWQ92_RS17915	COG1674	ftsk spoiiie
BWQ92_RS17925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BWQ92_RS17935	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS17950	COG1216	Glycosyl transferase, family 2
BWQ92_RS17990	COG0438	transferase activity, transferring glycosyl groups
BWQ92_RS18010	COG1132	(ABC) transporter
BWQ92_RS18025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWQ92_RS18155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BWQ92_RS18160	COG2884	Cell division ATP-binding protein ftsE
BWQ92_RS18175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BWQ92_RS18185	COG2801	Transposase and inactivated derivatives
BWQ92_RS18185	COG3415	Transposase
BWQ92_RS18190	COG2801	Transposase and inactivated derivatives
BWQ92_RS18230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BWQ92_RS18245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BWQ92_RS18250	COG0483	inositol monophosphate 1-phosphatase activity
BWQ92_RS18260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BWQ92_RS18270	COG1595	DNA-templated transcription, initiation
BWQ92_RS18295	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWQ92_RS18295	COG0567	Dehydrogenase, E1 component
BWQ92_RS18315	COG1121	(ABC) transporter
BWQ92_RS18335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWQ92_RS18345	COG1064	alcohol dehydrogenase
BWQ92_RS18350	COG0537	adenosine 5'-monophosphoramidase activity
BWQ92_RS18360	COG0477	Major facilitator Superfamily
BWQ92_RS18365	COG1643	Atp-dependent helicase
BWQ92_RS18390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWQ92_RS18405	COG0018	arginyl-trna synthetase
BWQ92_RS18410	COG0019	diaminopimelate decarboxylase activity
BWQ92_RS18415	COG0460	homoserine dehydrogenase
BWQ92_RS18420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BWQ92_RS18425	COG0083	homoserine kinase activity
BWQ92_RS18435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BWQ92_RS18440	COG2890	protein-(glutamine-N5) methyltransferase activity
BWQ92_RS18460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BWQ92_RS18475	COG0356	it plays a direct role in the translocation of protons across the membrane
BWQ92_RS18480	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BWQ92_RS18485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BWQ92_RS18490	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BWQ92_RS18495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BWQ92_RS18500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BWQ92_RS18505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BWQ92_RS18510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BWQ92_RS18525	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BWQ92_RS18540	COG0628	permease
BWQ92_RS18555	COG1902	pentaerythritol trinitrate reductase activity
BWQ92_RS18570	COG0363	glucosamine-6-phosphate deaminase activity
BWQ92_RS18585	COG1335	isochorismatase
BWQ92_RS18595	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BWQ92_RS18605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BWQ92_RS18610	COG1234	tRNA 3'-trailer cleavage
BWQ92_RS18615	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BWQ92_RS18620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BWQ92_RS18645	COG0420	3'-5' exonuclease activity
BWQ92_RS18650	COG0419	ATPase involved in DNA repair
BWQ92_RS18660	COG1414	Transcriptional regulator
BWQ92_RS18690	COG1113	amino acid transport
BWQ92_RS18700	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BWQ92_RS18705	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BWQ92_RS18715	COG1104	cysteine desulfurase activity
BWQ92_RS18735	COG1305	Transglutaminase-like
BWQ92_RS18745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWQ92_RS18755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWQ92_RS18760	COG0579	oxidoreductase
BWQ92_RS18765	COG0747	negative chemotaxis
BWQ92_RS18790	COG1609	Transcriptional regulator
BWQ92_RS18795	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS18810	COG1172	Belongs to the binding-protein-dependent transport system permease family
BWQ92_RS18820	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS18840	COG0228	four-way junction DNA binding
BWQ92_RS18845	COG0129	dihydroxy-acid dehydratase activity
BWQ92_RS18855	COG0440	acetolactate synthase activity
BWQ92_RS18860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BWQ92_RS18875	COG0577	efflux transmembrane transporter activity
BWQ92_RS18875	COG1136	(ABC) transporter
BWQ92_RS18895	COG0473	3-isopropylmalate dehydrogenase activity
BWQ92_RS18900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BWQ92_RS18910	COG0179	Fumarylacetoacetate (FAA) hydrolase
BWQ92_RS18915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BWQ92_RS18955	COG1414	Transcriptional regulator
BWQ92_RS18960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BWQ92_RS18965	COG0066	3-isopropylmalate dehydratase activity
BWQ92_RS18970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BWQ92_RS18980	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BWQ92_RS18985	COG1181	Belongs to the D-alanine--D-alanine ligase family
BWQ92_RS19010	COG0742	ribosomal rna small subunit methyltransferase
BWQ92_RS19025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BWQ92_RS19035	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BWQ92_RS19040	COG0571	ribonuclease III activity
BWQ92_RS19045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BWQ92_RS19050	COG1196	nuclear chromosome segregation
BWQ92_RS19060	COG0477	Major facilitator Superfamily
BWQ92_RS19075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BWQ92_RS19100	COG2514	catechol 2,3-dioxygenase activity
BWQ92_RS19110	COG0228	four-way junction DNA binding
BWQ92_RS19115	COG1837	Belongs to the UPF0109 family
BWQ92_RS19120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BWQ92_RS19125	COG0336	Belongs to the RNA methyltransferase TrmD family
BWQ92_RS19130	COG0335	large ribosomal subunit rRNA binding
BWQ92_RS19135	COG0681	Belongs to the peptidase S26 family
BWQ92_RS19145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BWQ92_RS19155	COG0792	nuclease activity
BWQ92_RS19215	COG0659	secondary active sulfate transmembrane transporter activity
BWQ92_RS19260	COG0785	Cytochrome C biogenesis protein
BWQ92_RS19280	COG2217	Heavy metal translocating P-type atpase
BWQ92_RS19285	COG2217	Heavy metal translocating P-type atpase
BWQ92_RS19300	COG1937	Protein conserved in bacteria
BWQ92_RS19395	COG2372	response to copper ion
BWQ92_RS19405	COG1742	UPF0060 membrane protein
BWQ92_RS19420	COG0640	Transcriptional regulator
BWQ92_RS19430	COG2814	Major facilitator Superfamily
BWQ92_RS19435	COG0477	Major facilitator Superfamily
BWQ92_RS19450	COG2226	methyltransferase
BWQ92_RS19455	COG2826	transposase and inactivated derivatives, IS30 family
BWQ92_RS19505	COG0210	DNA helicase
BWQ92_RS19540	COG4974	Belongs to the 'phage' integrase family
BWQ92_RS19550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BWQ92_RS19555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWQ92_RS19560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWQ92_RS19575	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BWQ92_RS19610	COG0477	Major facilitator Superfamily
BWQ92_RS19615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BWQ92_RS19620	COG2084	Dehydrogenase
BWQ92_RS19625	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS19640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BWQ92_RS19645	COG1045	serine acetyltransferase
BWQ92_RS19655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWQ92_RS19660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BWQ92_RS19670	COG3022	response to hydroperoxide
BWQ92_RS19710	COG0242	peptide deformylase activity
BWQ92_RS19735	COG1609	Transcriptional regulator
BWQ92_RS19740	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS19770	COG0629	single-stranded DNA binding
BWQ92_RS19785	COG1946	Acyl-CoA thioesterase
BWQ92_RS19800	COG0668	transmembrane transport
BWQ92_RS19845	COG0544	peptidyl-prolyl cis-trans isomerase activity
BWQ92_RS19850	COG0740	serine-type endopeptidase activity
BWQ92_RS19855	COG0740	serine-type endopeptidase activity
BWQ92_RS19860	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BWQ92_RS19865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BWQ92_RS19870	COG0525	valine-tRNA ligase activity
BWQ92_RS19875	COG3189	MarR family transcriptional regulator
BWQ92_RS19890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BWQ92_RS19895	COG0285	dihydrofolate synthase activity
BWQ92_RS19905	COG0105	UTP biosynthetic process
BWQ92_RS19915	COG1530	ribonuclease E activity
BWQ92_RS19920	COG0351	phosphomethylpyrimidine kinase
BWQ92_RS19920	COG0352	thiamine-phosphate diphosphorylase activity
BWQ92_RS19920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BWQ92_RS19925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BWQ92_RS19930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BWQ92_RS19935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BWQ92_RS19940	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BWQ92_RS19945	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BWQ92_RS19955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BWQ92_RS19965	COG0799	negative regulation of ribosome biogenesis
BWQ92_RS19990	COG0492	ferredoxin-NADP+ reductase activity
BWQ92_RS19995	COG2813	Specifically methylates the guanine in position
BWQ92_RS20000	COG1846	Transcriptional regulator
BWQ92_RS20000	COG1940	carbohydrate kinase activity
BWQ92_RS20020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BWQ92_RS20030	COG0583	DNA-binding transcription factor activity
BWQ92_RS20040	COG1780	Probably involved in ribonucleotide reductase function
BWQ92_RS20045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWQ92_RS20050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWQ92_RS20070	COG2197	response regulator
BWQ92_RS20085	COG3387	PFAM Glycoside hydrolase 15-related
BWQ92_RS20100	COG0656	L-ascorbic acid biosynthetic process
BWQ92_RS20110	COG0412	Dienelactone hydrolase
BWQ92_RS20130	COG1234	tRNA 3'-trailer cleavage
BWQ92_RS20160	COG3237	CsbD-like
BWQ92_RS20255	COG2135	peptidase activity
BWQ92_RS20265	COG1605	Chorismate mutase
BWQ92_RS20265	COG0077	Prephenate dehydratase
BWQ92_RS20280	COG0587	DNA-directed DNA polymerase activity
BWQ92_RS20285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BWQ92_RS20295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BWQ92_RS20300	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BWQ92_RS20320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BWQ92_RS20325	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BWQ92_RS20330	COG0217	transcriptional regulatory protein
BWQ92_RS20335	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BWQ92_RS20340	COG0632	four-way junction helicase activity
BWQ92_RS20345	COG2255	four-way junction helicase activity
BWQ92_RS20355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWQ92_RS20360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWQ92_RS20365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BWQ92_RS20375	COG1196	nuclear chromosome segregation
BWQ92_RS20385	COG0124	histidyl-tRNA synthetase
BWQ92_RS20395	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BWQ92_RS20405	COG0477	Major facilitator Superfamily
BWQ92_RS20415	COG1053	succinate dehydrogenase
BWQ92_RS20425	COG1414	Transcriptional regulator
BWQ92_RS20445	COG0633	Ferredoxin
BWQ92_RS20460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BWQ92_RS20475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BWQ92_RS20480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BWQ92_RS20490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BWQ92_RS20495	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BWQ92_RS20500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BWQ92_RS20505	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BWQ92_RS20515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BWQ92_RS20520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BWQ92_RS20530	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BWQ92_RS20535	COG0540	Belongs to the ATCase OTCase family
BWQ92_RS20540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BWQ92_RS20550	COG0505	Belongs to the CarA family
BWQ92_RS20555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BWQ92_RS20560	COG0284	orotidine-5'-phosphate decarboxylase activity
BWQ92_RS20565	COG0194	GDP metabolic process
BWQ92_RS20570	COG0194	GDP metabolic process
BWQ92_RS20575	COG1758	RNA polymerase activity
BWQ92_RS20585	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BWQ92_RS20595	COG0438	transferase activity, transferring glycosyl groups
BWQ92_RS20605	COG0656	L-ascorbic acid biosynthetic process
BWQ92_RS20620	COG2390	Transcriptional regulator
BWQ92_RS20625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BWQ92_RS20630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BWQ92_RS20635	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BWQ92_RS20640	COG0495	leucyl-tRNA aminoacylation
BWQ92_RS20645	COG1307	EDD domain protein, DegV family
BWQ92_RS20675	COG0268	Binds directly to 16S ribosomal RNA
BWQ92_RS20685	COG0481	GTPase activity
BWQ92_RS20690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BWQ92_RS20705	COG1420	regulation of RNA biosynthetic process
BWQ92_RS20710	COG0484	heat shock protein binding
BWQ92_RS20730	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BWQ92_RS20740	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BWQ92_RS20745	COG1316	TRANSCRIPTIONal
BWQ92_RS20750	COG3590	peptidase
BWQ92_RS20755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BWQ92_RS20760	COG1381	Involved in DNA repair and RecF pathway recombination
BWQ92_RS20765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BWQ92_RS20775	COG0167	dihydroorotate dehydrogenase activity
BWQ92_RS20795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BWQ92_RS20800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BWQ92_RS20810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWQ92_RS20815	COG2188	Transcriptional regulator
BWQ92_RS20820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BWQ92_RS20825	COG0723	plastoquinol--plastocyanin reductase activity
BWQ92_RS20830	COG2010	Cytochrome c
BWQ92_RS20835	COG1845	cytochrome c oxidase, subunit III
BWQ92_RS20840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BWQ92_RS20880	COG0583	DNA-binding transcription factor activity
BWQ92_RS20895	COG2226	methyltransferase
BWQ92_RS20910	COG0402	S-adenosylhomocysteine deaminase activity
BWQ92_RS20925	COG0402	S-adenosylhomocysteine deaminase activity
BWQ92_RS20945	COG3424	synthase
BWQ92_RS20955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWQ92_RS20960	COG0242	peptide deformylase activity
BWQ92_RS20965	COG0823	Involved in the tonB-independent uptake of proteins
BWQ92_RS20965	COG1506	peptidase
BWQ92_RS20965	COG4946	Tricorn protease homolog
BWQ92_RS20990	COG1216	Glycosyl transferase, family 2
BWQ92_RS20995	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BWQ92_RS21000	COG4581	dead DEAH box helicase
BWQ92_RS21005	COG0805	protein transport
BWQ92_RS21010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BWQ92_RS21030	COG0545	Peptidyl-prolyl cis-trans isomerase
BWQ92_RS21035	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BWQ92_RS21040	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BWQ92_RS21045	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BWQ92_RS21055	COG4122	O-methyltransferase activity
BWQ92_RS21060	COG1222	aaa ATPase
BWQ92_RS21070	COG0517	IMP dehydrogenase activity
BWQ92_RS21070	COG1994	Peptidase M50
BWQ92_RS21075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWQ92_RS21085	COG0215	cysteine-tRNA ligase activity
BWQ92_RS21090	COG1968	undecaprenyl-diphosphatase activity
BWQ92_RS21095	COG0656	L-ascorbic acid biosynthetic process
BWQ92_RS21115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWQ92_RS21175	COG0583	DNA-binding transcription factor activity
BWQ92_RS21185	COG1301	dicarboxylic acid transport
BWQ92_RS21190	COG1929	Belongs to the glycerate kinase type-1 family
BWQ92_RS21210	COG0435	Glutathione S-transferase
BWQ92_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS21230	COG0183	Belongs to the thiolase family
BWQ92_RS21245	COG0297	glycogen (starch) synthase activity
BWQ92_RS21250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWQ92_RS21280	COG2308	Evidence 4 Homologs of previously reported genes of
BWQ92_RS21285	COG2855	membrane
BWQ92_RS21300	COG0254	rRNA binding
BWQ92_RS21310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BWQ92_RS21315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BWQ92_RS21320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWQ92_RS21340	COG1119	ATPase activity
BWQ92_RS21345	COG0640	Transcriptional regulator
BWQ92_RS21360	COG0477	Major facilitator Superfamily
BWQ92_RS21365	COG0671	phosphoesterase, PA-phosphatase related
BWQ92_RS21370	COG3830	Belongs to the UPF0237 family
BWQ92_RS21370	COG0560	Phosphoserine phosphatase
BWQ92_RS21380	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS21385	COG1028	Short-chain dehydrogenase reductase Sdr
BWQ92_RS21420	COG0488	(ABC) transporter
BWQ92_RS21425	COG1268	BioY protein
BWQ92_RS21430	COG1122	ATPase activity
BWQ92_RS21640	COG2313	pseudouridylate synthase activity
BWQ92_RS21645	COG1597	lipid kinase activity
BWQ92_RS21665	COG2318	DinB family
BWQ92_RS21695	COG3848	Pyruvate phosphate dikinase
BWQ92_RS21695	COG0574	Belongs to the PEP-utilizing enzyme family
BWQ92_RS21720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BWQ92_RS21735	COG0183	Belongs to the thiolase family
BWQ92_RS21740	COG0318	PFAM AMP-dependent synthetase and ligase
BWQ92_RS21750	COG2151	metal-sulfur cluster biosynthetic enzyme
BWQ92_RS21755	COG0396	ATPase activity
BWQ92_RS21780	COG1131	(ABC) transporter
BWQ92_RS21790	COG1612	heme a metabolic process
BWQ92_RS21795	COG0109	protoheme IX farnesyltransferase activity
BWQ92_RS21805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BWQ92_RS21810	COG0166	Belongs to the GPI family
BWQ92_RS21825	COG0363	glucosamine-6-phosphate deaminase activity
BWQ92_RS21835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWQ92_RS21840	COG0149	triose-phosphate isomerase activity
BWQ92_RS21845	COG0126	phosphoglycerate kinase activity
BWQ92_RS21850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWQ92_RS21855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BWQ92_RS21860	COG1481	regulation of sporulation
BWQ92_RS21865	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BWQ92_RS21870	COG1660	Displays ATPase and GTPase activities
BWQ92_RS21875	COG0322	excinuclease ABC activity
BWQ92_RS21885	COG0546	phosphoglycolate phosphatase activity
BWQ92_RS21910	COG4106	trans-aconitate 2-methyltransferase activity
BWQ92_RS21950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWQ92_RS21980	COG0556	nucleotide-excision repair
BWQ92_RS21985	COG0237	dephospho-CoA kinase activity
BWQ92_RS21985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BWQ92_RS21990	COG1739	Uncharacterized protein family UPF0029
BWQ92_RS21995	COG0693	protein deglycase activity
BWQ92_RS22000	COG0539	negative regulation of cytoplasmic translation
BWQ92_RS22005	COG4552	Acetyltransferase involved in intracellular survival and related
BWQ92_RS22015	COG2050	protein possibly involved in aromatic compounds catabolism
BWQ92_RS22040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWQ92_RS22045	COG2814	Major facilitator Superfamily
BWQ92_RS22060	COG0179	Fumarylacetoacetate (FAA) hydrolase
BWQ92_RS22070	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BWQ92_RS22090	COG0009	L-threonylcarbamoyladenylate synthase
BWQ92_RS22165	COG1222	aaa ATPase
BWQ92_RS22175	COG2197	response regulator
BWQ92_RS22210	COG1196	nuclear chromosome segregation
BWQ92_RS22210	COG0741	lytic transglycosylase activity
BWQ92_RS22210	COG0739	heme binding
BWQ92_RS22225	COG0438	transferase activity, transferring glycosyl groups
BWQ92_RS22230	COG1643	Atp-dependent helicase
BWQ92_RS22255	COG1752	Esterase of the alpha-beta hydrolase superfamily
BWQ92_RS22275	COG0405	Gamma-glutamyltransferase
BWQ92_RS22290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWQ92_RS22355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BWQ92_RS22365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BWQ92_RS22375	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BWQ92_RS22380	COG2124	cytochrome p450
BWQ92_RS22425	COG3387	PFAM Glycoside hydrolase 15-related
BWQ92_RS22435	COG1012	belongs to the aldehyde dehydrogenase family
BWQ92_RS22450	COG1252	NADH dehydrogenase
BWQ92_RS22465	COG3415	Transposase
BWQ92_RS22465	COG2801	Transposase and inactivated derivatives
BWQ92_RS22510	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BWQ92_RS22510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BWQ92_RS22515	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BWQ92_RS22545	COG0583	DNA-binding transcription factor activity
BWQ92_RS22565	COG1404	Belongs to the peptidase S8 family
BWQ92_RS22590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWQ92_RS22595	COG0318	PFAM AMP-dependent synthetase and ligase
BWQ92_RS22600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWQ92_RS22615	COG2824	Alkylphosphonate utilization operon protein PhnA
BWQ92_RS22625	COG0659	secondary active sulfate transmembrane transporter activity
BWQ92_RS22630	COG1793	dna ligase
BWQ92_RS22635	COG0464	growth
BWQ92_RS22640	COG2814	Major facilitator Superfamily
BWQ92_RS22650	COG0673	inositol 2-dehydrogenase activity
BWQ92_RS22660	COG1609	Transcriptional regulator
BWQ92_RS22680	COG1172	Belongs to the binding-protein-dependent transport system permease family
BWQ92_RS22685	COG1129	ABC transporter
BWQ92_RS22690	COG4213	ABC transporter substrate-binding protein
BWQ92_RS22700	COG2801	Transposase and inactivated derivatives
BWQ92_RS22710	COG1063	alcohol dehydrogenase
BWQ92_RS22725	COG0477	Major facilitator Superfamily
BWQ92_RS22730	COG1802	Transcriptional regulator
BWQ92_RS22740	COG1621	beta-fructofuranosidase activity
BWQ92_RS22745	COG1609	Transcriptional regulator
BWQ92_RS22750	COG0395	ABC-type sugar transport system, permease component
BWQ92_RS22880	COG2610	gluconate transmembrane transporter activity
BWQ92_RS22885	COG0800	Aldolase
BWQ92_RS22890	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BWQ92_RS22905	COG1414	Transcriptional regulator
BWQ92_RS23025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
