locus-tag	class	description
LDN82_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LDN82_RS00010	COG0592	DNA-directed DNA polymerase activity
LDN82_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LDN82_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDN82_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LDN82_RS00030	COG0187	DNA topoisomerase II activity
LDN82_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LDN82_RS00040	COG3266	domain, Protein
LDN82_RS00070	COG1215	transferase activity, transferring glycosyl groups
LDN82_RS00085	COG0457	Tetratricopeptide repeat
LDN82_RS00085	COG0705	Rhomboid family
LDN82_RS00095	COG2818	Glycosylase
LDN82_RS00105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LDN82_RS00105	COG2169	Transcriptional regulator
LDN82_RS00125	COG3764	Sortase (surface protein transpeptidase)
LDN82_RS00135	COG0515	serine threonine protein kinase
LDN82_RS00140	COG0515	serine threonine protein kinase
LDN82_RS00145	COG0768	penicillin binding
LDN82_RS00160	COG1716	ATPase activity
LDN82_RS00165	COG1716	ATPase activity
LDN82_RS00175	COG2188	Transcriptional regulator
LDN82_RS00205	COG0346	lactoylglutathione lyase activity
LDN82_RS00220	COG2186	Transcriptional regulator
LDN82_RS00225	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LDN82_RS00230	COG0477	Major facilitator Superfamily
LDN82_RS00235	COG1984	allophanate hydrolase subunit 2
LDN82_RS00240	COG4770	biotin carboxylase activity
LDN82_RS00245	COG0277	FAD linked oxidase domain protein
LDN82_RS00250	COG0385	Bile acid
LDN82_RS00255	COG0659	secondary active sulfate transmembrane transporter activity
LDN82_RS00280	COG0561	phosphatase activity
LDN82_RS00300	COG0584	glycerophosphoryl diester phosphodiesterase
LDN82_RS00310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDN82_RS00315	COG1929	Belongs to the glycerate kinase type-1 family
LDN82_RS00335	COG1082	Xylose isomerase domain protein TIM barrel
LDN82_RS00340	COG2271	Major facilitator Superfamily
LDN82_RS00345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LDN82_RS00350	COG0693	protein deglycase activity
LDN82_RS00360	COG3655	Transcriptional regulator
LDN82_RS00365	COG2233	PERMEase
LDN82_RS00375	COG0778	Nitroreductase
LDN82_RS00395	COG3104	oligopeptide transport
LDN82_RS00405	COG3340	Belongs to the peptidase S51 family
LDN82_RS00410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDN82_RS00410	COG0425	Belongs to the sulfur carrier protein TusA family
LDN82_RS00425	COG1597	lipid kinase activity
LDN82_RS00430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LDN82_RS00435	COG0561	phosphatase activity
LDN82_RS00450	COG1191	sigma factor activity
LDN82_RS00460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LDN82_RS00465	COG0859	PFAM glycosyl transferase family 9
LDN82_RS00475	COG0438	transferase activity, transferring glycosyl groups
LDN82_RS00480	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LDN82_RS00485	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LDN82_RS00485	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LDN82_RS00500	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LDN82_RS00500	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LDN82_RS00575	COG0037	tRNA processing
LDN82_RS00585	COG1609	Transcriptional regulator
LDN82_RS00590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LDN82_RS00595	COG0302	gtp cyclohydrolase
LDN82_RS00605	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LDN82_RS00635	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LDN82_RS00640	COG2814	Major facilitator Superfamily
LDN82_RS00700	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LDN82_RS00725	COG0823	Involved in the tonB-independent uptake of proteins
LDN82_RS00725	COG1506	peptidase
LDN82_RS00735	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LDN82_RS00745	COG2376	Dihydroxyacetone kinase
LDN82_RS00750	COG1461	Dihydroxyacetone kinase
LDN82_RS00755	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LDN82_RS00760	COG3237	CsbD-like
LDN82_RS00790	COG1301	dicarboxylic acid transport
LDN82_RS00810	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LDN82_RS00830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LDN82_RS00845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDN82_RS00910	COG0436	Aminotransferase
LDN82_RS00915	COG0586	Pfam SNARE associated Golgi protein
LDN82_RS00920	COG0831	urea catabolic process
LDN82_RS00925	COG0832	Belongs to the urease beta subunit family
LDN82_RS00930	COG0804	urea catabolic process
LDN82_RS00935	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LDN82_RS00940	COG0830	nickel cation binding
LDN82_RS00945	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LDN82_RS00950	COG0829	nickel cation binding
LDN82_RS00955	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LDN82_RS00995	COG0656	L-ascorbic acid biosynthetic process
LDN82_RS01005	COG0667	Aldo Keto reductase
LDN82_RS01010	COG0656	L-ascorbic acid biosynthetic process
LDN82_RS01020	COG3360	Dodecin
LDN82_RS01025	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS01035	COG2186	Transcriptional regulator
LDN82_RS01040	COG2267	carboxylic ester hydrolase activity
LDN82_RS01050	COG2084	Dehydrogenase
LDN82_RS01055	COG2610	gluconate transmembrane transporter activity
LDN82_RS01115	COG0076	glutamate decarboxylase activity
LDN82_RS01120	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LDN82_RS01155	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS01165	COG0667	Aldo Keto reductase
LDN82_RS01180	COG0346	lactoylglutathione lyase activity
LDN82_RS01185	COG0697	spore germination
LDN82_RS01190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDN82_RS01195	COG0477	Major facilitator Superfamily
LDN82_RS01200	COG2890	protein-(glutamine-N5) methyltransferase activity
LDN82_RS01215	COG1793	dna ligase
LDN82_RS01215	COG3285	dna ligase
LDN82_RS01220	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LDN82_RS01225	COG0395	ABC-type sugar transport system, permease component
LDN82_RS01230	COG1175	transmembrane transport
LDN82_RS01245	COG2188	Transcriptional regulator
LDN82_RS01285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDN82_RS01290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDN82_RS01290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDN82_RS01290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDN82_RS01295	COG1105	Belongs to the carbohydrate kinase PfkB family
LDN82_RS01300	COG1349	DNA-binding transcription factor activity
LDN82_RS01320	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LDN82_RS01345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDN82_RS01375	COG1846	Transcriptional regulator
LDN82_RS01400	COG0142	geranyltranstransferase activity
LDN82_RS01405	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LDN82_RS01410	COG1846	Transcriptional regulator
LDN82_RS01445	COG2186	Transcriptional regulator
LDN82_RS01460	COG0129	dihydroxy-acid dehydratase activity
LDN82_RS01465	COG0028	Belongs to the TPP enzyme family
LDN82_RS01490	COG1802	Transcriptional regulator
LDN82_RS01500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LDN82_RS01510	COG1126	abc transporter atp-binding protein
LDN82_RS01515	COG0765	amino acid transport
LDN82_RS01520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN82_RS01530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDN82_RS01535	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS01540	COG0473	3-isopropylmalate dehydrogenase activity
LDN82_RS01570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN82_RS01575	COG4172	Belongs to the ABC transporter superfamily
LDN82_RS01585	COG5006	permease, DMT superfamily
LDN82_RS01595	COG0673	inositol 2-dehydrogenase activity
LDN82_RS01620	COG0395	ABC-type sugar transport system, permease component
LDN82_RS01625	COG1063	alcohol dehydrogenase
LDN82_RS01645	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LDN82_RS01660	COG2733	membrane
LDN82_RS01695	COG4122	O-methyltransferase activity
LDN82_RS01715	COG0583	DNA-binding transcription factor activity
LDN82_RS01725	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS01735	COG1131	(ABC) transporter
LDN82_RS01740	COG3559	Exporter of polyketide antibiotics
LDN82_RS01755	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LDN82_RS01775	COG2902	Dehydrogenase
LDN82_RS01790	COG2252	PERMEase
LDN82_RS01795	COG2372	response to copper ion
LDN82_RS01815	COG3848	Pyruvate phosphate dikinase
LDN82_RS01815	COG0574	Belongs to the PEP-utilizing enzyme family
LDN82_RS01845	COG3655	Transcriptional regulator
LDN82_RS01870	COG0395	ABC-type sugar transport system, permease component
LDN82_RS01875	COG1175	transmembrane transport
LDN82_RS01880	COG1285	pathogenesis
LDN82_RS01905	COG1302	Protein conserved in bacteria
LDN82_RS01945	COG1653	transport
LDN82_RS01950	COG1175	transmembrane transport
LDN82_RS01955	COG0395	ABC-type sugar transport system, permease component
LDN82_RS01980	COG2197	response regulator
LDN82_RS01985	COG4585	Histidine kinase
LDN82_RS02000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDN82_RS02045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LDN82_RS02060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDN82_RS02065	COG0303	'Molybdopterin
LDN82_RS02070	COG1063	alcohol dehydrogenase
LDN82_RS02085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LDN82_RS02090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDN82_RS02095	COG3404	Formiminotransferase-cyclodeaminase
LDN82_RS02110	COG1802	Transcriptional regulator
LDN82_RS02115	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LDN82_RS02130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDN82_RS02135	COG2197	response regulator
LDN82_RS02160	COG0415	Belongs to the DNA photolyase family
LDN82_RS02170	COG1024	Enoyl-CoA hydratase
LDN82_RS02220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDN82_RS02225	COG1960	acyl-CoA dehydrogenase activity
LDN82_RS02240	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS02260	COG0789	Transcriptional regulator
LDN82_RS02265	COG1695	Transcriptional regulator
LDN82_RS02275	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS02280	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LDN82_RS02290	COG0531	amino acid
LDN82_RS02295	COG2186	Transcriptional regulator
LDN82_RS02305	COG1609	Transcriptional regulator
LDN82_RS02320	COG0747	negative chemotaxis
LDN82_RS02330	COG0444	Belongs to the ABC transporter superfamily
LDN82_RS02335	COG4172	Belongs to the ABC transporter superfamily
LDN82_RS02345	COG0673	inositol 2-dehydrogenase activity
LDN82_RS02350	COG1609	Transcriptional regulator
LDN82_RS02355	COG1904	glucuronate isomerase
LDN82_RS02360	COG0246	Mannitol dehydrogenase
LDN82_RS02365	COG4948	Mandelate Racemase Muconate Lactonizing
LDN82_RS02375	COG4213	ABC transporter substrate-binding protein
LDN82_RS02380	COG1129	ABC transporter
LDN82_RS02385	COG4214	carbohydrate transport
LDN82_RS02390	COG1609	Transcriptional regulator
LDN82_RS02400	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN82_RS02415	COG2814	Major facilitator Superfamily
LDN82_RS02420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDN82_RS02425	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LDN82_RS02500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LDN82_RS02505	COG0477	Major facilitator Superfamily
LDN82_RS02525	COG0604	alcohol dehydrogenase
LDN82_RS02525	COG3321	synthase
LDN82_RS02550	COG1175	transmembrane transport
LDN82_RS02555	COG0395	ABC-type sugar transport system, permease component
LDN82_RS02560	COG3622	Belongs to the hyi family
LDN82_RS02605	COG5002	protein histidine kinase activity
LDN82_RS02635	COG1940	carbohydrate kinase activity
LDN82_RS02640	COG0673	inositol 2-dehydrogenase activity
LDN82_RS02655	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN82_RS02665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDN82_RS02675	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN82_RS02680	COG0477	Major facilitator Superfamily
LDN82_RS02695	COG2814	Major facilitator Superfamily
LDN82_RS02700	COG2186	Transcriptional regulator
LDN82_RS02715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN82_RS02720	COG0765	amino acid transport
LDN82_RS02725	COG1126	abc transporter atp-binding protein
LDN82_RS02755	COG0477	Major facilitator Superfamily
LDN82_RS02795	COG2197	response regulator
LDN82_RS02825	COG0765	amino acid transport
LDN82_RS02830	COG1126	abc transporter atp-binding protein
LDN82_RS02835	COG0673	inositol 2-dehydrogenase activity
LDN82_RS02865	COG1832	CoA-binding protein
LDN82_RS02875	COG2315	Protein conserved in bacteria
LDN82_RS02885	COG1653	transport
LDN82_RS02890	COG1175	transmembrane transport
LDN82_RS02895	COG0395	ABC-type sugar transport system, permease component
LDN82_RS02910	COG2368	4-hydroxyphenylacetate
LDN82_RS02945	COG3706	GGDEF domain
LDN82_RS02960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LDN82_RS02965	COG0047	phosphoribosylformylglycinamidine synthase activity
LDN82_RS02985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDN82_RS03020	COG0024	Methionine aminopeptidase
LDN82_RS03025	COG1846	Transcriptional regulator
LDN82_RS03040	COG5416	Lipopolysaccharide assembly protein A domain
LDN82_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS03105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LDN82_RS03120	COG1876	peptidase activity
LDN82_RS03130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDN82_RS03145	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS03185	COG0739	heme binding
LDN82_RS03185	COG0741	lytic transglycosylase activity
LDN82_RS03185	COG1196	nuclear chromosome segregation
LDN82_RS03190	COG0386	Belongs to the glutathione peroxidase family
LDN82_RS03195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LDN82_RS03220	COG1309	transcriptional regulator
LDN82_RS03225	COG2271	Major facilitator Superfamily
LDN82_RS03235	COG1609	Transcriptional regulator
LDN82_RS03245	COG1175	transmembrane transport
LDN82_RS03250	COG0395	ABC-type sugar transport system, permease component
LDN82_RS03265	COG0438	transferase activity, transferring glycosyl groups
LDN82_RS03280	COG0589	response to stress
LDN82_RS03300	COG3290	protein histidine kinase activity
LDN82_RS03305	COG4565	transcriptional regulatory protein
LDN82_RS03340	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDN82_RS03345	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN82_RS03350	COG0145	ligase activity
LDN82_RS03365	COG3962	Belongs to the TPP enzyme family
LDN82_RS03370	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS03375	COG0673	inositol 2-dehydrogenase activity
LDN82_RS03380	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS03385	COG0129	dihydroxy-acid dehydratase activity
LDN82_RS03400	COG0673	inositol 2-dehydrogenase activity
LDN82_RS03405	COG1129	ABC transporter
LDN82_RS03410	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDN82_RS03420	COG0247	lactate metabolic process
LDN82_RS03420	COG0277	FAD linked oxidase domain protein
LDN82_RS03450	COG4702	Belongs to the UPF0303 family
LDN82_RS03460	COG0823	Involved in the tonB-independent uptake of proteins
LDN82_RS03470	COG0673	inositol 2-dehydrogenase activity
LDN82_RS03475	COG0673	inositol 2-dehydrogenase activity
LDN82_RS03485	COG0395	ABC-type sugar transport system, permease component
LDN82_RS03495	COG2182	Extracellular solute-binding protein
LDN82_RS03500	COG0673	inositol 2-dehydrogenase activity
LDN82_RS03510	COG1846	Transcriptional regulator
LDN82_RS03510	COG1940	carbohydrate kinase activity
LDN82_RS03515	COG2807	transmembrane transport
LDN82_RS03520	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LDN82_RS03530	COG1476	TRANSCRIPTIONal
LDN82_RS03540	COG1309	transcriptional regulator
LDN82_RS03550	COG0351	phosphomethylpyrimidine kinase
LDN82_RS03560	COG2205	protein histidine kinase activity
LDN82_RS03565	COG0745	RESPONSE REGULATOR receiver
LDN82_RS03570	COG0477	Major facilitator Superfamily
LDN82_RS03585	COG0343	queuine tRNA-ribosyltransferase activity
LDN82_RS03605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDN82_RS03615	COG0477	Major facilitator Superfamily
LDN82_RS03620	COG2508	Transcriptional regulator
LDN82_RS03625	COG0477	Major facilitator Superfamily
LDN82_RS03630	COG0028	Belongs to the TPP enzyme family
LDN82_RS03635	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS03640	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LDN82_RS03645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDN82_RS03665	COG3842	ATPase activity
LDN82_RS03720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LDN82_RS03745	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LDN82_RS03755	COG0586	Pfam SNARE associated Golgi protein
LDN82_RS03770	COG0492	ferredoxin-NADP+ reductase activity
LDN82_RS03780	COG0564	pseudouridine synthase activity
LDN82_RS03805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDN82_RS03810	COG2364	Membrane
LDN82_RS03815	COG0395	ABC-type sugar transport system, permease component
LDN82_RS03820	COG1175	transmembrane transport
LDN82_RS03830	COG1609	Transcriptional regulator
LDN82_RS03835	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDN82_RS03840	COG1201	RNA secondary structure unwinding
LDN82_RS03865	COG2271	Major facilitator Superfamily
LDN82_RS03910	COG0438	transferase activity, transferring glycosyl groups
LDN82_RS03930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LDN82_RS03955	COG0789	Transcriptional regulator
LDN82_RS03965	COG2205	protein histidine kinase activity
LDN82_RS03970	COG0745	RESPONSE REGULATOR receiver
LDN82_RS03980	COG2062	phosphohistidine phosphatase, SixA
LDN82_RS03990	COG0730	response to heat
LDN82_RS03995	COG0402	S-adenosylhomocysteine deaminase activity
LDN82_RS04000	COG2271	Major facilitator Superfamily
LDN82_RS04015	COG0583	DNA-binding transcription factor activity
LDN82_RS04020	COG0697	spore germination
LDN82_RS04030	COG1309	transcriptional regulator
LDN82_RS04035	COG1511	domain protein
LDN82_RS04050	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LDN82_RS04055	COG1940	carbohydrate kinase activity
LDN82_RS04060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDN82_RS04065	COG4608	Belongs to the ABC transporter superfamily
LDN82_RS04070	COG0444	Belongs to the ABC transporter superfamily
LDN82_RS04080	COG0747	negative chemotaxis
LDN82_RS04095	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LDN82_RS04100	COG1017	nitric oxide dioxygenase activity
LDN82_RS04100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDN82_RS04115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDN82_RS04120	COG0514	ATP-dependent DNA helicase (RecQ)
LDN82_RS04125	COG0477	Major facilitator Superfamily
LDN82_RS04135	COG1505	serine-type exopeptidase activity
LDN82_RS04145	COG1113	amino acid transport
LDN82_RS04170	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS04170	COG3321	synthase
LDN82_RS04170	COG0604	alcohol dehydrogenase
LDN82_RS04180	COG1966	Carbon starvation protein
LDN82_RS04200	COG0656	L-ascorbic acid biosynthetic process
LDN82_RS04210	COG0154	amidase activity
LDN82_RS04230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDN82_RS04240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDN82_RS04250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDN82_RS04260	COG0444	Belongs to the ABC transporter superfamily
LDN82_RS04265	COG4608	Belongs to the ABC transporter superfamily
LDN82_RS04290	COG1335	isochorismatase
LDN82_RS04345	COG0154	amidase activity
LDN82_RS04365	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LDN82_RS04370	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LDN82_RS04390	COG0588	phosphoglycerate mutase activity
LDN82_RS04420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LDN82_RS04425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LDN82_RS04435	COG0215	cysteine-tRNA ligase activity
LDN82_RS04440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDN82_RS04470	COG0366	Alpha amylase catalytic
LDN82_RS04480	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LDN82_RS04515	COG1609	Transcriptional regulator
LDN82_RS04520	COG0366	Alpha amylase catalytic
LDN82_RS04535	COG3833	ABC-type maltose transport systems, permease component
LDN82_RS04540	COG0366	Alpha amylase catalytic
LDN82_RS04545	COG0277	FAD linked oxidase domain protein
LDN82_RS04560	COG0402	S-adenosylhomocysteine deaminase activity
LDN82_RS04565	COG4608	Belongs to the ABC transporter superfamily
LDN82_RS04570	COG0444	Belongs to the ABC transporter superfamily
LDN82_RS04575	COG0601	transmembrane transport
LDN82_RS04580	COG0747	negative chemotaxis
LDN82_RS04585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN82_RS04590	COG0402	S-adenosylhomocysteine deaminase activity
LDN82_RS04610	COG3842	ATPase activity
LDN82_RS04635	COG0475	glutathione-regulated potassium exporter activity
LDN82_RS04645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LDN82_RS04650	COG0588	phosphoglycerate mutase activity
LDN82_RS04655	COG1252	NADH dehydrogenase
LDN82_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS04695	COG1960	acyl-CoA dehydrogenase activity
LDN82_RS04705	COG0477	Major facilitator Superfamily
LDN82_RS04720	COG0579	oxidoreductase
LDN82_RS04740	COG2957	Belongs to the agmatine deiminase family
LDN82_RS04765	COG0477	Major facilitator Superfamily
LDN82_RS04775	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDN82_RS04775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDN82_RS04780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDN82_RS04785	COG0509	glycine decarboxylation via glycine cleavage system
LDN82_RS04790	COG1760	l-serine dehydratase
LDN82_RS04795	COG1864	DNA RNA non-specific endonuclease
LDN82_RS04795	COG3591	Belongs to the peptidase S1B family
LDN82_RS04810	COG1136	(ABC) transporter
LDN82_RS04810	COG0577	efflux transmembrane transporter activity
LDN82_RS04835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LDN82_RS04855	COG0459	protein refolding
LDN82_RS04860	COG0328	RNA-DNA hybrid ribonuclease activity
LDN82_RS04870	COG2205	protein histidine kinase activity
LDN82_RS04875	COG0745	RESPONSE REGULATOR receiver
LDN82_RS04885	COG0583	DNA-binding transcription factor activity
LDN82_RS04895	COG2132	Multicopper oxidase
LDN82_RS04920	COG1278	Cold shock
LDN82_RS04940	COG0739	heme binding
LDN82_RS04945	COG0791	NLP P60 protein
LDN82_RS04945	COG1388	LysM domain
LDN82_RS04945	COG3103	Sh3 type 3 domain protein
LDN82_RS04975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDN82_RS04985	COG1126	abc transporter atp-binding protein
LDN82_RS04990	COG0765	amino acid transport
LDN82_RS04995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN82_RS05010	COG0488	(ABC) transporter
LDN82_RS05015	COG1132	(ABC) transporter
LDN82_RS05020	COG0494	nUDIX hydrolase
LDN82_RS05050	COG0483	inositol monophosphate 1-phosphatase activity
LDN82_RS05065	COG0045	succinate-CoA ligase (ADP-forming) activity
LDN82_RS05080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDN82_RS05090	COG3962	Belongs to the TPP enzyme family
LDN82_RS05105	COG0673	inositol 2-dehydrogenase activity
LDN82_RS05110	COG1082	Xylose isomerase domain protein TIM barrel
LDN82_RS05115	COG3718	enzyme involved in inositol metabolism
LDN82_RS05120	COG2188	Transcriptional regulator
LDN82_RS05130	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDN82_RS05155	COG0673	inositol 2-dehydrogenase activity
LDN82_RS05165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDN82_RS05165	COG0519	Catalyzes the synthesis of GMP from XMP
LDN82_RS05205	COG1396	sequence-specific DNA binding
LDN82_RS05220	COG0028	Belongs to the TPP enzyme family
LDN82_RS05255	COG1621	beta-fructofuranosidase activity
LDN82_RS05270	COG1653	transport
LDN82_RS05280	COG0395	ABC-type sugar transport system, permease component
LDN82_RS05290	COG1609	Transcriptional regulator
LDN82_RS05295	COG1621	beta-fructofuranosidase activity
LDN82_RS05315	COG1175	transmembrane transport
LDN82_RS05320	COG0395	ABC-type sugar transport system, permease component
LDN82_RS05325	COG1609	Transcriptional regulator
LDN82_RS05340	COG1175	transmembrane transport
LDN82_RS05345	COG0395	ABC-type sugar transport system, permease component
LDN82_RS05370	COG0741	lytic transglycosylase activity
LDN82_RS05370	COG0739	heme binding
LDN82_RS05370	COG1196	nuclear chromosome segregation
LDN82_RS05375	COG1401	restriction endodeoxyribonuclease activity
LDN82_RS05390	COG5002	protein histidine kinase activity
LDN82_RS05395	COG0745	RESPONSE REGULATOR receiver
LDN82_RS05400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LDN82_RS05425	COG0604	alcohol dehydrogenase
LDN82_RS05435	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS05450	COG1024	Enoyl-CoA hydratase
LDN82_RS05455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDN82_RS05465	COG0477	Major facilitator Superfamily
LDN82_RS05470	COG1396	sequence-specific DNA binding
LDN82_RS05490	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LDN82_RS05500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDN82_RS05505	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LDN82_RS05535	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LDN82_RS05540	COG1902	pentaerythritol trinitrate reductase activity
LDN82_RS05555	COG2376	Dihydroxyacetone kinase
LDN82_RS05560	COG0698	ribose 5-phosphate isomerase
LDN82_RS05565	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN82_RS05570	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS05575	COG2271	Major facilitator Superfamily
LDN82_RS05580	COG0149	triose-phosphate isomerase activity
LDN82_RS05610	COG2183	response to ionizing radiation
LDN82_RS05625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LDN82_RS05635	COG1254	Belongs to the acylphosphatase family
LDN82_RS05650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDN82_RS05655	COG2186	Transcriptional regulator
LDN82_RS05660	COG0477	Major facilitator Superfamily
LDN82_RS05670	COG0640	Transcriptional regulator
LDN82_RS05675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDN82_RS05715	COG3550	peptidyl-serine autophosphorylation
LDN82_RS05730	COG0477	Major facilitator Superfamily
LDN82_RS05735	COG0640	Transcriptional regulator
LDN82_RS05750	COG3973	AAA domain
LDN82_RS05755	COG3321	synthase
LDN82_RS05755	COG0604	alcohol dehydrogenase
LDN82_RS05765	COG1309	transcriptional regulator
LDN82_RS05800	COG1131	(ABC) transporter
LDN82_RS05810	COG0640	Transcriptional regulator
LDN82_RS05875	COG1401	restriction endodeoxyribonuclease activity
LDN82_RS05910	COG0531	amino acid
LDN82_RS05925	COG2801	Transposase and inactivated derivatives
LDN82_RS05995	COG2732	(Barnase) inhibitor
LDN82_RS06025	COG2072	flavoprotein involved in K transport
LDN82_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS06050	COG1278	Cold shock
LDN82_RS06070	COG1846	Transcriptional regulator
LDN82_RS06100	COG2755	lipolytic protein G-D-S-L family
LDN82_RS06105	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LDN82_RS06110	COG0438	transferase activity, transferring glycosyl groups
LDN82_RS06125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDN82_RS06145	COG0789	Transcriptional regulator
LDN82_RS06155	COG0484	heat shock protein binding
LDN82_RS06170	COG2268	Band 7 protein
LDN82_RS06200	COG0477	Major facilitator Superfamily
LDN82_RS06205	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LDN82_RS06215	COG0138	bifunctional purine biosynthesis protein purh
LDN82_RS06225	COG2838	Isocitrate dehydrogenase
LDN82_RS06240	COG0673	inositol 2-dehydrogenase activity
LDN82_RS06250	COG1136	(ABC) transporter
LDN82_RS06250	COG0577	efflux transmembrane transporter activity
LDN82_RS06255	COG0577	efflux transmembrane transporter activity
LDN82_RS06255	COG1136	(ABC) transporter
LDN82_RS06260	COG1136	(ABC) transporter
LDN82_RS06275	COG4213	ABC transporter substrate-binding protein
LDN82_RS06285	COG1129	ABC transporter
LDN82_RS06295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDN82_RS06305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDN82_RS06310	COG0531	amino acid
LDN82_RS06340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDN82_RS06345	COG4585	Histidine kinase
LDN82_RS06350	COG2197	response regulator
LDN82_RS06360	COG1131	(ABC) transporter
LDN82_RS06380	COG0708	Exodeoxyribonuclease III
LDN82_RS06385	COG0180	Tryptophanyl-tRNA synthetase
LDN82_RS06420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LDN82_RS06435	COG2009	succinate dehydrogenase
LDN82_RS06445	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LDN82_RS06445	COG1473	amidohydrolase
LDN82_RS06450	COG1846	Transcriptional regulator
LDN82_RS06455	COG1764	response to oxidative stress
LDN82_RS06460	COG2130	NADP-dependent
LDN82_RS06465	COG1744	ABC transporter substrate-binding protein PnrA-like
LDN82_RS06470	COG3845	ABC transporter
LDN82_RS06475	COG4603	Belongs to the binding-protein-dependent transport system permease family
LDN82_RS06480	COG1079	Belongs to the binding-protein-dependent transport system permease family
LDN82_RS06500	COG0586	Pfam SNARE associated Golgi protein
LDN82_RS06505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LDN82_RS06515	COG0148	phosphopyruvate hydratase activity
LDN82_RS06540	COG1252	NADH dehydrogenase
LDN82_RS06585	COG0183	Belongs to the thiolase family
LDN82_RS06590	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LDN82_RS06600	COG2017	converts alpha-aldose to the beta-anomer
LDN82_RS06610	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LDN82_RS06620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDN82_RS06630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LDN82_RS06640	COG1331	Highly conserved protein containing a thioredoxin domain
LDN82_RS06650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LDN82_RS06655	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LDN82_RS06685	COG0114	fumarate hydratase activity
LDN82_RS06690	COG0288	reversible hydration of carbon dioxide
LDN82_RS06700	COG1494	fructose-1,6-bisphosphatase
LDN82_RS06770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LDN82_RS06775	COG1376	ErfK ybiS ycfS ynhG family protein
LDN82_RS06780	COG1357	PFAM Pentapeptide repeats (8 copies)
LDN82_RS06830	COG0714	Associated with various cellular activities
LDN82_RS06835	COG0084	hydrolase, TatD family'
LDN82_RS06840	COG3583	domain protein
LDN82_RS06845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LDN82_RS06850	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LDN82_RS06855	COG0488	(ABC) transporter
LDN82_RS06865	COG2801	Transposase and inactivated derivatives
LDN82_RS06870	COG1309	transcriptional regulator
LDN82_RS06880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LDN82_RS06890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LDN82_RS06895	COG0193	aminoacyl-tRNA hydrolase activity
LDN82_RS06920	COG0822	iron-sulfur transferase activity
LDN82_RS06925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LDN82_RS06940	COG0702	epimerase
LDN82_RS06950	COG1988	membrane-bound metal-dependent
LDN82_RS06970	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LDN82_RS07030	COG0640	Transcriptional regulator
LDN82_RS07050	COG2814	Major facilitator Superfamily
LDN82_RS07065	COG0583	DNA-binding transcription factor activity
LDN82_RS07075	COG3395	kinase activity
LDN82_RS07080	COG0235	Class ii aldolase
LDN82_RS07085	COG1621	beta-fructofuranosidase activity
LDN82_RS07090	COG0395	ABC-type sugar transport system, permease component
LDN82_RS07095	COG1175	transmembrane transport
LDN82_RS07105	COG1609	Transcriptional regulator
LDN82_RS07120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDN82_RS07120	COG2146	nitrite reductase [NAD(P)H] activity
LDN82_RS07130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDN82_RS07135	COG1621	beta-fructofuranosidase activity
LDN82_RS07175	COG0243	molybdopterin cofactor binding
LDN82_RS07180	COG2223	nitrite transmembrane transporter activity
LDN82_RS07185	COG0477	Major facilitator Superfamily
LDN82_RS07190	COG4770	biotin carboxylase activity
LDN82_RS07195	COG0424	maF-like protein
LDN82_RS07200	COG1011	Hydrolase
LDN82_RS07205	COG2409	Drug exporters of the RND superfamily
LDN82_RS07220	COG0393	Putative heavy-metal-binding
LDN82_RS07225	COG1823	symporter activity
LDN82_RS07240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LDN82_RS07245	COG0300	oxidoreductase activity
LDN82_RS07250	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LDN82_RS07250	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LDN82_RS07270	COG0714	Associated with various cellular activities
LDN82_RS07290	COG0631	protein serine/threonine phosphatase activity
LDN82_RS07310	COG1674	ftsk spoiiie
LDN82_RS07315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LDN82_RS07320	COG0483	inositol monophosphate 1-phosphatase activity
LDN82_RS07330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN82_RS07335	COG1116	anion transmembrane transporter activity
LDN82_RS07340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDN82_RS07360	COG0251	oxidation-reduction process
LDN82_RS07365	COG4565	transcriptional regulatory protein
LDN82_RS07375	COG2851	Citrate transporter
LDN82_RS07380	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LDN82_RS07385	COG0154	amidase activity
LDN82_RS07390	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LDN82_RS07405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LDN82_RS07410	COG4209	transmembrane transport
LDN82_RS07415	COG0395	ABC-type sugar transport system, permease component
LDN82_RS07430	COG0673	inositol 2-dehydrogenase activity
LDN82_RS07440	COG1063	alcohol dehydrogenase
LDN82_RS07445	COG0156	8-amino-7-oxononanoate synthase activity
LDN82_RS07455	COG1228	amidohydrolase
LDN82_RS07490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDN82_RS07495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDN82_RS07500	COG1940	carbohydrate kinase activity
LDN82_RS07520	COG0588	phosphoglycerate mutase activity
LDN82_RS07535	COG2873	o-acetylhomoserine
LDN82_RS07540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDN82_RS07575	COG0423	glycine-tRNA ligase activity
LDN82_RS07605	COG0358	DNA primase activity
LDN82_RS07625	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LDN82_RS07630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LDN82_RS07640	COG2814	Major facilitator Superfamily
LDN82_RS07650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LDN82_RS07685	COG0052	Belongs to the universal ribosomal protein uS2 family
LDN82_RS07690	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LDN82_RS07695	COG0528	UMP kinase activity
LDN82_RS07700	COG0233	cytoplasmic translational termination
LDN82_RS07705	COG0575	Belongs to the CDS family
LDN82_RS07720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDN82_RS07730	COG3279	Response regulator of the LytR AlgR family
LDN82_RS07735	COG3275	phosphorelay sensor kinase activity
LDN82_RS07745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDN82_RS07750	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LDN82_RS07750	COG1796	DNA polymerase
LDN82_RS07770	COG1522	sequence-specific DNA binding
LDN82_RS07780	COG0022	dehydrogenase e1 component
LDN82_RS07785	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN82_RS07790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDN82_RS07805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LDN82_RS07815	COG1960	acyl-CoA dehydrogenase activity
LDN82_RS07840	COG0673	inositol 2-dehydrogenase activity
LDN82_RS07850	COG1082	Xylose isomerase domain protein TIM barrel
LDN82_RS07855	COG0673	inositol 2-dehydrogenase activity
LDN82_RS07865	COG1175	transmembrane transport
LDN82_RS07870	COG1653	transport
LDN82_RS07875	COG1609	Transcriptional regulator
LDN82_RS07885	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LDN82_RS07890	COG0750	zinc metalloprotease
LDN82_RS07900	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LDN82_RS07925	COG0442	prolyl-tRNA aminoacylation
LDN82_RS07935	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
LDN82_RS07950	COG0779	Required for maturation of 30S ribosomal subunits
LDN82_RS07955	COG0195	Participates in both transcription termination and antitermination
LDN82_RS07965	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LDN82_RS07965	COG0481	GTPase activity
LDN82_RS07970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LDN82_RS07975	COG0590	tRNA wobble adenosine to inosine editing
LDN82_RS07985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LDN82_RS08005	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LDN82_RS08010	COG1185	polyribonucleotide nucleotidyltransferase activity
LDN82_RS08015	COG0612	Peptidase, M16
LDN82_RS08035	COG0745	RESPONSE REGULATOR receiver
LDN82_RS08040	COG2205	protein histidine kinase activity
LDN82_RS08060	COG0521	Mo-molybdopterin cofactor biosynthetic process
LDN82_RS08070	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LDN82_RS08095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDN82_RS08100	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LDN82_RS08105	COG1674	ftsk spoiiie
LDN82_RS08115	COG1058	Belongs to the CinA family
LDN82_RS08115	COG1546	Belongs to the CinA family
LDN82_RS08120	COG1396	sequence-specific DNA binding
LDN82_RS08135	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LDN82_RS08140	COG2137	regulation of response to DNA damage stimulus
LDN82_RS08145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LDN82_RS08150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LDN82_RS08155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LDN82_RS08160	COG2813	Specifically methylates the guanine in position
LDN82_RS08165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LDN82_RS08175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LDN82_RS08180	COG1388	LysM domain
LDN82_RS08185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDN82_RS08190	COG0131	Imidazoleglycerol-phosphate dehydratase
LDN82_RS08195	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LDN82_RS08205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LDN82_RS08225	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LDN82_RS08230	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LDN82_RS08235	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LDN82_RS08240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDN82_RS08250	COG2814	Major facilitator Superfamily
LDN82_RS08280	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LDN82_RS08285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDN82_RS08285	COG0072	phenylalanine-tRNA ligase activity
LDN82_RS08320	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LDN82_RS08325	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LDN82_RS08330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LDN82_RS08335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LDN82_RS08340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LDN82_RS08345	COG1438	arginine binding
LDN82_RS08350	COG0137	argininosuccinate synthase activity
LDN82_RS08355	COG0165	Argininosuccinate lyase
LDN82_RS08370	COG2094	Belongs to the DNA glycosylase MPG family
LDN82_RS08380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LDN82_RS08405	COG0647	UMP catabolic process
LDN82_RS08420	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LDN82_RS08425	COG0497	DNA recombination
LDN82_RS08430	COG0504	CTP synthase activity
LDN82_RS08460	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LDN82_RS08465	COG2079	MmgE PrpD family protein
LDN82_RS08490	COG3290	protein histidine kinase activity
LDN82_RS08495	COG1301	dicarboxylic acid transport
LDN82_RS08505	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LDN82_RS08510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LDN82_RS08525	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LDN82_RS08535	COG1160	GTP binding
LDN82_RS08550	COG2814	Major facilitator Superfamily
LDN82_RS08560	COG0509	glycine decarboxylation via glycine cleavage system
LDN82_RS08565	COG1716	ATPase activity
LDN82_RS08590	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LDN82_RS08600	COG1940	carbohydrate kinase activity
LDN82_RS08625	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LDN82_RS08630	COG0515	serine threonine protein kinase
LDN82_RS08630	COG2815	serine threonine protein kinase
LDN82_RS08635	COG1388	LysM domain
LDN82_RS08635	COG3942	CHAP domain
LDN82_RS08645	COG0142	geranyltranstransferase activity
LDN82_RS08655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LDN82_RS08665	COG2001	Belongs to the MraZ family
LDN82_RS08670	COG0275	rRNA processing
LDN82_RS08680	COG0768	penicillin binding
LDN82_RS08685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LDN82_RS08690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDN82_RS08695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDN82_RS08700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LDN82_RS08710	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LDN82_RS08715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LDN82_RS08725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LDN82_RS08740	COG1799	cell septum assembly
LDN82_RS08755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LDN82_RS08765	COG0587	DNA-directed DNA polymerase activity
LDN82_RS08780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDN82_RS08785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LDN82_RS08790	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS08810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LDN82_RS08815	COG0174	glutamine synthetase
LDN82_RS08820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LDN82_RS08860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LDN82_RS08865	COG0321	lipoyl(octanoyl) transferase activity
LDN82_RS08875	COG1090	epimerase
LDN82_RS08880	COG4946	Tricorn protease homolog
LDN82_RS08880	COG0793	Belongs to the peptidase S41A family
LDN82_RS08885	COG1764	response to oxidative stress
LDN82_RS08895	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN82_RS08900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDN82_RS08905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LDN82_RS08925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDN82_RS08960	COG1271	oxidase subunit
LDN82_RS08965	COG1294	oxidase, subunit
LDN82_RS08970	COG4988	ABC transporter
LDN82_RS08990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LDN82_RS08995	COG0045	succinate-CoA ligase (ADP-forming) activity
LDN82_RS08995	COG1042	CoA-binding domain protein
LDN82_RS08995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDN82_RS09010	COG1435	thymidine kinase activity
LDN82_RS09030	COG0756	dUTP diphosphatase activity
LDN82_RS09055	COG0569	domain protein
LDN82_RS09060	COG0531	amino acid
LDN82_RS09065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDN82_RS09070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LDN82_RS09075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LDN82_RS09095	COG0667	Aldo Keto reductase
LDN82_RS09100	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN82_RS09100	COG1024	Enoyl-CoA hydratase
LDN82_RS09105	COG0183	Belongs to the thiolase family
LDN82_RS09135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDN82_RS09150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LDN82_RS09170	COG3135	benzoate transporter
LDN82_RS09180	COG0531	amino acid
LDN82_RS09230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDN82_RS09270	COG0242	peptide deformylase activity
LDN82_RS09275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LDN82_RS09285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LDN82_RS09305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDN82_RS09305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDN82_RS09315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LDN82_RS09320	COG0140	phosphoribosyl-ATP diphosphatase activity
LDN82_RS09325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LDN82_RS09330	COG0107	imidazoleglycerol-phosphate synthase activity
LDN82_RS09340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LDN82_RS09360	COG0134	indole-3-glycerol-phosphate synthase activity
LDN82_RS09365	COG0133	tryptophan synthase activity
LDN82_RS09370	COG0159	tryptophan synthase activity
LDN82_RS09375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LDN82_RS09380	COG0067	glutamate synthase
LDN82_RS09380	COG0070	glutamate synthase
LDN82_RS09380	COG0069	glutamate synthase activity
LDN82_RS09470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN82_RS09485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN82_RS09505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDN82_RS09510	COG0657	acetylesterase activity
LDN82_RS09515	COG0318	PFAM AMP-dependent synthetase and ligase
LDN82_RS09520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LDN82_RS09560	COG1454	alcohol dehydrogenase
LDN82_RS09620	COG0028	Belongs to the TPP enzyme family
LDN82_RS09630	COG1024	Enoyl-CoA hydratase
LDN82_RS09630	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN82_RS09645	COG0318	PFAM AMP-dependent synthetase and ligase
LDN82_RS09655	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS09670	COG1129	ABC transporter
LDN82_RS09680	COG1414	Transcriptional regulator
LDN82_RS09690	COG3415	Transposase
LDN82_RS09690	COG2801	Transposase and inactivated derivatives
LDN82_RS09705	COG0183	Belongs to the thiolase family
LDN82_RS09725	COG1309	transcriptional regulator
LDN82_RS09730	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS09765	COG1454	alcohol dehydrogenase
LDN82_RS09780	COG3415	Transposase
LDN82_RS09780	COG2801	Transposase and inactivated derivatives
LDN82_RS09805	COG2271	Major facilitator Superfamily
LDN82_RS09840	COG3284	Transcriptional regulator
LDN82_RS09855	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS09865	COG2267	carboxylic ester hydrolase activity
LDN82_RS09870	COG2072	flavoprotein involved in K transport
LDN82_RS09875	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LDN82_RS09880	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LDN82_RS09890	COG2072	flavoprotein involved in K transport
LDN82_RS09895	COG0657	acetylesterase activity
LDN82_RS09925	COG0535	radical SAM domain protein
LDN82_RS09980	COG1024	Enoyl-CoA hydratase
LDN82_RS10000	COG1024	Enoyl-CoA hydratase
LDN82_RS10005	COG1024	Enoyl-CoA hydratase
LDN82_RS10035	COG0778	Nitroreductase
LDN82_RS10045	COG1063	alcohol dehydrogenase
LDN82_RS10065	COG1760	l-serine dehydratase
LDN82_RS10085	COG0210	DNA helicase
LDN82_RS10160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LDN82_RS10200	COG0561	phosphatase activity
LDN82_RS10205	COG1105	Belongs to the carbohydrate kinase PfkB family
LDN82_RS10225	COG0028	Belongs to the TPP enzyme family
LDN82_RS10240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDN82_RS10245	COG0583	DNA-binding transcription factor activity
LDN82_RS10260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN82_RS10265	COG0444	Belongs to the ABC transporter superfamily
LDN82_RS10270	COG4608	Belongs to the ABC transporter superfamily
LDN82_RS10300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDN82_RS10305	COG1113	amino acid transport
LDN82_RS10350	COG2084	Dehydrogenase
LDN82_RS10360	COG0583	DNA-binding transcription factor activity
LDN82_RS10365	COG1929	Belongs to the glycerate kinase type-1 family
LDN82_RS10370	COG0436	Aminotransferase
LDN82_RS10395	COG3654	unkown
LDN82_RS10405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDN82_RS10415	COG0436	Aminotransferase
LDN82_RS10420	COG3961	Belongs to the TPP enzyme family
LDN82_RS10430	COG3250	beta-galactosidase activity
LDN82_RS10455	COG1175	transmembrane transport
LDN82_RS10460	COG0395	ABC-type sugar transport system, permease component
LDN82_RS10475	COG0022	dehydrogenase e1 component
LDN82_RS10480	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN82_RS10560	COG3422	double-strand break repair
LDN82_RS10600	COG0745	RESPONSE REGULATOR receiver
LDN82_RS10640	COG1609	Transcriptional regulator
LDN82_RS10660	COG0395	ABC-type sugar transport system, permease component
LDN82_RS10670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDN82_RS10680	COG1482	cell wall glycoprotein biosynthetic process
LDN82_RS10685	COG2971	BadF BadG BcrA BcrD
LDN82_RS10755	COG0076	glutamate decarboxylase activity
LDN82_RS10760	COG1846	Transcriptional regulator
LDN82_RS10775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LDN82_RS10785	COG3119	arylsulfatase activity
LDN82_RS10790	COG0747	negative chemotaxis
LDN82_RS10805	COG4608	Belongs to the ABC transporter superfamily
LDN82_RS10815	COG3119	arylsulfatase activity
LDN82_RS10825	COG3119	arylsulfatase activity
LDN82_RS10855	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN82_RS10865	COG0148	phosphopyruvate hydratase activity
LDN82_RS10870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDN82_RS10900	COG1609	Transcriptional regulator
LDN82_RS10905	COG2814	Major facilitator Superfamily
LDN82_RS10925	COG0183	Belongs to the thiolase family
LDN82_RS10935	COG1073	alpha beta
LDN82_RS10940	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS10950	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS10955	COG2267	carboxylic ester hydrolase activity
LDN82_RS10975	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LDN82_RS10990	COG0800	Aldolase
LDN82_RS11000	COG1609	Transcriptional regulator
LDN82_RS11040	COG0395	ABC-type sugar transport system, permease component
LDN82_RS11055	COG1793	dna ligase
LDN82_RS11090	COG1609	Transcriptional regulator
LDN82_RS11095	COG1609	Transcriptional regulator
LDN82_RS11100	COG0747	negative chemotaxis
LDN82_RS11120	COG3250	beta-galactosidase activity
LDN82_RS11125	COG3507	Belongs to the glycosyl hydrolase 43 family
LDN82_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS11165	COG1472	Belongs to the glycosyl hydrolase 3 family
LDN82_RS11170	COG2084	Dehydrogenase
LDN82_RS11175	COG1082	Xylose isomerase domain protein TIM barrel
LDN82_RS11180	COG0149	triose-phosphate isomerase activity
LDN82_RS11185	COG0698	ribose 5-phosphate isomerase
LDN82_RS11190	COG2376	Dihydroxyacetone kinase
LDN82_RS11200	COG2186	Transcriptional regulator
LDN82_RS11215	COG1733	regulation of RNA biosynthetic process
LDN82_RS11235	COG4176	ABC-type proline glycine betaine transport system permease component
LDN82_RS11240	COG0517	IMP dehydrogenase activity
LDN82_RS11240	COG4175	Glycine betaine
LDN82_RS11245	COG0583	DNA-binding transcription factor activity
LDN82_RS11290	COG2197	response regulator
LDN82_RS11310	COG0028	Belongs to the TPP enzyme family
LDN82_RS11315	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LDN82_RS11320	COG1233	COG1233 Phytoene dehydrogenase and related
LDN82_RS11325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LDN82_RS11335	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS11355	COG1793	dna ligase
LDN82_RS11355	COG3285	dna ligase
LDN82_RS11360	COG0028	Belongs to the TPP enzyme family
LDN82_RS11365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDN82_RS11385	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS11390	COG0460	homoserine dehydrogenase
LDN82_RS11400	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LDN82_RS11435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LDN82_RS11455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDN82_RS11465	COG3795	YCII-related domain
LDN82_RS11470	COG4941	Belongs to the sigma-70 factor family
LDN82_RS11490	COG1064	alcohol dehydrogenase
LDN82_RS11495	COG1643	Atp-dependent helicase
LDN82_RS11540	COG0009	L-threonylcarbamoyladenylate synthase
LDN82_RS11560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDN82_RS11565	COG2971	BadF BadG BcrA BcrD
LDN82_RS11575	COG2188	Transcriptional regulator
LDN82_RS11590	COG3483	tryptophan 2,3-dioxygenase activity
LDN82_RS11625	COG2050	protein possibly involved in aromatic compounds catabolism
LDN82_RS11635	COG4552	Acetyltransferase involved in intracellular survival and related
LDN82_RS11645	COG0539	negative regulation of cytoplasmic translation
LDN82_RS11655	COG1739	Uncharacterized protein family UPF0029
LDN82_RS11660	COG0237	dephospho-CoA kinase activity
LDN82_RS11660	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LDN82_RS11665	COG0556	nucleotide-excision repair
LDN82_RS11675	COG0477	Major facilitator Superfamily
LDN82_RS11690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDN82_RS11700	COG4106	trans-aconitate 2-methyltransferase activity
LDN82_RS11715	COG0546	phosphoglycolate phosphatase activity
LDN82_RS11725	COG0322	excinuclease ABC activity
LDN82_RS11730	COG1660	Displays ATPase and GTPase activities
LDN82_RS11740	COG1481	regulation of sporulation
LDN82_RS11745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LDN82_RS11750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDN82_RS11755	COG0126	phosphoglycerate kinase activity
LDN82_RS11760	COG0149	triose-phosphate isomerase activity
LDN82_RS11765	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDN82_RS11775	COG0363	glucosamine-6-phosphate deaminase activity
LDN82_RS11790	COG0166	Belongs to the GPI family
LDN82_RS11795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LDN82_RS11805	COG0109	protoheme IX farnesyltransferase activity
LDN82_RS11810	COG1612	heme a metabolic process
LDN82_RS11820	COG1131	(ABC) transporter
LDN82_RS11835	COG0719	Fe-S assembly protein
LDN82_RS11845	COG0396	ATPase activity
LDN82_RS11850	COG2151	metal-sulfur cluster biosynthetic enzyme
LDN82_RS11865	COG0318	PFAM AMP-dependent synthetase and ligase
LDN82_RS11870	COG0183	Belongs to the thiolase family
LDN82_RS11880	COG1122	ATPase activity
LDN82_RS11885	COG1268	BioY protein
LDN82_RS11890	COG0488	(ABC) transporter
LDN82_RS11915	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS11920	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS11925	COG1129	ABC transporter
LDN82_RS11945	COG0560	Phosphoserine phosphatase
LDN82_RS11945	COG3830	Belongs to the UPF0237 family
LDN82_RS11950	COG1119	ATPase activity
LDN82_RS11970	COG0254	rRNA binding
LDN82_RS11985	COG2855	membrane
LDN82_RS12010	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LDN82_RS12015	COG0297	glycogen (starch) synthase activity
LDN82_RS12030	COG0183	Belongs to the thiolase family
LDN82_RS12080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDN82_RS12095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LDN82_RS12115	COG0438	transferase activity, transferring glycosyl groups
LDN82_RS12160	COG1088	dTDP-glucose 4,6-dehydratase activity
LDN82_RS12165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LDN82_RS12170	COG0656	L-ascorbic acid biosynthetic process
LDN82_RS12175	COG1968	undecaprenyl-diphosphatase activity
LDN82_RS12180	COG0215	cysteine-tRNA ligase activity
LDN82_RS12190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDN82_RS12195	COG1994	Peptidase M50
LDN82_RS12195	COG0517	IMP dehydrogenase activity
LDN82_RS12205	COG1222	aaa ATPase
LDN82_RS12210	COG4122	O-methyltransferase activity
LDN82_RS12220	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LDN82_RS12225	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LDN82_RS12230	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LDN82_RS12235	COG0545	Peptidyl-prolyl cis-trans isomerase
LDN82_RS12255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDN82_RS12260	COG0805	protein transport
LDN82_RS12265	COG4581	dead DEAH box helicase
LDN82_RS12270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LDN82_RS12275	COG1216	Glycosyl transferase, family 2
LDN82_RS12295	COG2226	methyltransferase
LDN82_RS12305	COG0242	peptide deformylase activity
LDN82_RS12320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDN82_RS12325	COG3424	synthase
LDN82_RS12330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDN82_RS12355	COG4974	Belongs to the 'phage' integrase family
LDN82_RS12395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LDN82_RS12400	COG1845	cytochrome c oxidase, subunit III
LDN82_RS12405	COG2010	Cytochrome c
LDN82_RS12410	COG0723	plastoquinol--plastocyanin reductase activity
LDN82_RS12415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LDN82_RS12420	COG2188	Transcriptional regulator
LDN82_RS12425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDN82_RS12435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDN82_RS12440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LDN82_RS12460	COG0167	dihydroorotate dehydrogenase activity
LDN82_RS12475	COG0596	Alpha beta hydrolase
LDN82_RS12475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDN82_RS12475	COG2226	methyltransferase
LDN82_RS12480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LDN82_RS12485	COG1381	Involved in DNA repair and RecF pathway recombination
LDN82_RS12490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDN82_RS12495	COG3590	peptidase
LDN82_RS12500	COG1316	TRANSCRIPTIONal
LDN82_RS12505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LDN82_RS12515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LDN82_RS12530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LDN82_RS12535	COG0484	heat shock protein binding
LDN82_RS12540	COG1420	regulation of RNA biosynthetic process
LDN82_RS12560	COG0481	GTPase activity
LDN82_RS12570	COG0268	Binds directly to 16S ribosomal RNA
LDN82_RS12590	COG1307	EDD domain protein, DegV family
LDN82_RS12595	COG0495	leucyl-tRNA aminoacylation
LDN82_RS12600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LDN82_RS12605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LDN82_RS12610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDN82_RS12615	COG2390	Transcriptional regulator
LDN82_RS12620	COG0656	L-ascorbic acid biosynthetic process
LDN82_RS12640	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LDN82_RS12650	COG1758	RNA polymerase activity
LDN82_RS12655	COG0194	GDP metabolic process
LDN82_RS12665	COG0284	orotidine-5'-phosphate decarboxylase activity
LDN82_RS12670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LDN82_RS12675	COG0505	Belongs to the CarA family
LDN82_RS12685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDN82_RS12690	COG0540	Belongs to the ATCase OTCase family
LDN82_RS12695	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LDN82_RS12705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDN82_RS12710	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LDN82_RS12720	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LDN82_RS12725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LDN82_RS12730	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LDN82_RS12735	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDN82_RS12750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LDN82_RS12765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LDN82_RS12785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LDN82_RS12790	COG0124	histidyl-tRNA synthetase
LDN82_RS12800	COG1196	nuclear chromosome segregation
LDN82_RS12810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDN82_RS12815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDN82_RS12820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDN82_RS12830	COG2255	four-way junction helicase activity
LDN82_RS12835	COG0632	four-way junction helicase activity
LDN82_RS12840	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LDN82_RS12845	COG0217	transcriptional regulatory protein
LDN82_RS12850	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LDN82_RS12870	COG0339	signal peptide processing
LDN82_RS12875	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LDN82_RS12880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LDN82_RS12890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LDN82_RS12895	COG0587	DNA-directed DNA polymerase activity
LDN82_RS12920	COG2135	peptidase activity
LDN82_RS12955	COG0723	plastoquinol--plastocyanin reductase activity
LDN82_RS12965	COG4804	nuclease activity
LDN82_RS13000	COG0758	DNA mediated transformation
LDN82_RS13025	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDN82_RS13035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDN82_RS13040	COG1780	Probably involved in ribonucleotide reductase function
LDN82_RS13050	COG0583	DNA-binding transcription factor activity
LDN82_RS13060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LDN82_RS13090	COG0714	Associated with various cellular activities
LDN82_RS13105	COG1175	transmembrane transport
LDN82_RS13120	COG2813	Specifically methylates the guanine in position
LDN82_RS13145	COG0799	negative regulation of ribosome biogenesis
LDN82_RS13155	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LDN82_RS13165	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LDN82_RS13170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LDN82_RS13175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LDN82_RS13180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LDN82_RS13185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LDN82_RS13190	COG0351	phosphomethylpyrimidine kinase
LDN82_RS13190	COG0352	thiamine-phosphate diphosphorylase activity
LDN82_RS13190	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LDN82_RS13195	COG1530	ribonuclease E activity
LDN82_RS13205	COG0105	UTP biosynthetic process
LDN82_RS13215	COG0285	dihydrofolate synthase activity
LDN82_RS13220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LDN82_RS13235	COG3189	MarR family transcriptional regulator
LDN82_RS13240	COG0525	valine-tRNA ligase activity
LDN82_RS13245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDN82_RS13250	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LDN82_RS13255	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LDN82_RS13260	COG0740	serine-type endopeptidase activity
LDN82_RS13265	COG0740	serine-type endopeptidase activity
LDN82_RS13270	COG0544	peptidyl-prolyl cis-trans isomerase activity
LDN82_RS13315	COG0668	transmembrane transport
LDN82_RS13330	COG1946	Acyl-CoA thioesterase
LDN82_RS13355	COG0629	single-stranded DNA binding
LDN82_RS13390	COG0242	peptide deformylase activity
LDN82_RS13420	COG3022	response to hydroperoxide
LDN82_RS13430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDN82_RS13435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDN82_RS13445	COG1045	serine acetyltransferase
LDN82_RS13450	COG0300	oxidoreductase activity
LDN82_RS13455	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LDN82_RS13465	COG1063	alcohol dehydrogenase
LDN82_RS13470	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS13475	COG2084	Dehydrogenase
LDN82_RS13485	COG0477	Major facilitator Superfamily
LDN82_RS13520	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LDN82_RS13535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDN82_RS13540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDN82_RS13555	COG4974	Belongs to the 'phage' integrase family
LDN82_RS13570	COG0792	nuclease activity
LDN82_RS13580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LDN82_RS13590	COG0681	Belongs to the peptidase S26 family
LDN82_RS13595	COG0335	large ribosomal subunit rRNA binding
LDN82_RS13600	COG0336	Belongs to the RNA methyltransferase TrmD family
LDN82_RS13605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LDN82_RS13610	COG1837	Belongs to the UPF0109 family
LDN82_RS13615	COG0228	four-way junction DNA binding
LDN82_RS13625	COG2514	catechol 2,3-dioxygenase activity
LDN82_RS13650	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LDN82_RS13665	COG2814	Major facilitator Superfamily
LDN82_RS13705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDN82_RS13710	COG0571	ribonuclease III activity
LDN82_RS13715	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LDN82_RS13725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LDN82_RS13740	COG0742	ribosomal rna small subunit methyltransferase
LDN82_RS13750	COG1461	Dihydroxyacetone kinase
LDN82_RS13765	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDN82_RS13770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LDN82_RS13780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LDN82_RS13785	COG0066	3-isopropylmalate dehydratase activity
LDN82_RS13790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LDN82_RS13795	COG1414	Transcriptional regulator
LDN82_RS13830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDN82_RS13835	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN82_RS13840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDN82_RS13845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDN82_RS13850	COG0473	3-isopropylmalate dehydrogenase activity
LDN82_RS13855	COG4585	Histidine kinase
LDN82_RS13860	COG2197	response regulator
LDN82_RS13865	COG0577	efflux transmembrane transporter activity
LDN82_RS13865	COG1136	(ABC) transporter
LDN82_RS13880	COG0577	efflux transmembrane transporter activity
LDN82_RS13880	COG1136	(ABC) transporter
LDN82_RS13890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDN82_RS13895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LDN82_RS13900	COG0440	acetolactate synthase activity
LDN82_RS13910	COG0129	dihydroxy-acid dehydratase activity
LDN82_RS13915	COG0088	Forms part of the polypeptide exit tunnel
LDN82_RS13920	COG2133	pyrroloquinoline quinone binding
LDN82_RS13950	COG0747	negative chemotaxis
LDN82_RS13955	COG0579	oxidoreductase
LDN82_RS13960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDN82_RS13965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN82_RS13975	COG1305	Transglutaminase-like
LDN82_RS14005	COG1104	cysteine desulfurase activity
LDN82_RS14015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LDN82_RS14020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LDN82_RS14030	COG1522	sequence-specific DNA binding
LDN82_RS14035	COG1113	amino acid transport
LDN82_RS14045	COG0022	dehydrogenase e1 component
LDN82_RS14050	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN82_RS14070	COG0477	Major facilitator Superfamily
LDN82_RS14090	COG2207	Transcriptional regulator
LDN82_RS14100	COG1116	anion transmembrane transporter activity
LDN82_RS14105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDN82_RS14115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LDN82_RS14135	COG0419	ATPase involved in DNA repair
LDN82_RS14140	COG0420	3'-5' exonuclease activity
LDN82_RS14155	COG2149	membrane
LDN82_RS14175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LDN82_RS14180	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LDN82_RS14185	COG1234	tRNA 3'-trailer cleavage
LDN82_RS14190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LDN82_RS14200	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LDN82_RS14210	COG1335	isochorismatase
LDN82_RS14225	COG0363	glucosamine-6-phosphate deaminase activity
LDN82_RS14240	COG1902	pentaerythritol trinitrate reductase activity
LDN82_RS14255	COG0628	permease
LDN82_RS14270	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LDN82_RS14285	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LDN82_RS14290	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LDN82_RS14300	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LDN82_RS14305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LDN82_RS14310	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LDN82_RS14315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LDN82_RS14320	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDN82_RS14325	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LDN82_RS14330	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDN82_RS14335	COG0356	it plays a direct role in the translocation of protons across the membrane
LDN82_RS14350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDN82_RS14370	COG2890	protein-(glutamine-N5) methyltransferase activity
LDN82_RS14375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LDN82_RS14385	COG0083	homoserine kinase activity
LDN82_RS14390	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LDN82_RS14395	COG0460	homoserine dehydrogenase
LDN82_RS14400	COG0019	diaminopimelate decarboxylase activity
LDN82_RS14405	COG0018	arginyl-trna synthetase
LDN82_RS14420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDN82_RS14420	COG1017	nitric oxide dioxygenase activity
LDN82_RS14450	COG1643	Atp-dependent helicase
LDN82_RS14455	COG0537	adenosine 5'-monophosphoramidase activity
LDN82_RS14460	COG1064	alcohol dehydrogenase
LDN82_RS14485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDN82_RS14490	COG1121	(ABC) transporter
LDN82_RS14505	COG1253	flavin adenine dinucleotide binding
LDN82_RS14510	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN82_RS14510	COG0567	Dehydrogenase, E1 component
LDN82_RS14535	COG1595	DNA-templated transcription, initiation
LDN82_RS14545	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LDN82_RS14555	COG0483	inositol monophosphate 1-phosphatase activity
LDN82_RS14560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDN82_RS14585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDN82_RS14595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LDN82_RS14605	COG2177	Part of the ABC transporter FtsEX involved in
LDN82_RS14610	COG2884	Cell division ATP-binding protein ftsE
LDN82_RS14615	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LDN82_RS14700	COG1216	Glycosyl transferase, family 2
LDN82_RS14715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LDN82_RS14745	COG2902	Dehydrogenase
LDN82_RS14780	COG0653	protein targeting
LDN82_RS14785	COG3214	Protein conserved in bacteria
LDN82_RS14790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LDN82_RS14795	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LDN82_RS14800	COG5401	PFAM Sporulation and spore germination
LDN82_RS14805	COG5002	protein histidine kinase activity
LDN82_RS14810	COG0745	RESPONSE REGULATOR receiver
LDN82_RS14830	COG0714	Associated with various cellular activities
LDN82_RS14870	COG0601	transmembrane transport
LDN82_RS14890	COG0482	sulfurtransferase activity
LDN82_RS14925	COG0484	heat shock protein binding
LDN82_RS14930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LDN82_RS14950	COG3265	gluconokinase activity
LDN82_RS14955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LDN82_RS14960	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LDN82_RS14965	COG2086	electron transfer activity
LDN82_RS14970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDN82_RS14980	COG1842	Phage shock protein A
LDN82_RS14985	COG2188	Transcriptional regulator
LDN82_RS15000	COG1615	UPF0182 protein
LDN82_RS15005	COG3480	Lon protease (S16) C-terminal proteolytic domain
LDN82_RS15025	COG2816	NAD+ diphosphatase activity
LDN82_RS15055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN82_RS15060	COG0765	amino acid transport
LDN82_RS15065	COG1126	abc transporter atp-binding protein
LDN82_RS15075	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDN82_RS15085	COG0113	porphobilinogen synthase activity
LDN82_RS15095	COG0181	hydroxymethylbilane synthase activity
LDN82_RS15100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LDN82_RS15105	COG3253	May function as heme-dependent peroxidase
LDN82_RS15110	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LDN82_RS15115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LDN82_RS15120	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LDN82_RS15135	COG1309	transcriptional regulator
LDN82_RS15150	COG2154	pterin-4-alpha-carbinolamine dehydratase
LDN82_RS15165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDN82_RS15165	COG2022	thiamine diphosphate biosynthetic process
LDN82_RS15170	COG0352	thiamine-phosphate diphosphorylase activity
LDN82_RS15185	COG0513	Belongs to the DEAD box helicase family
LDN82_RS15205	COG0006	proline dipeptidase activity
LDN82_RS15215	COG2239	Acts as a magnesium transporter
LDN82_RS15230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDN82_RS15240	COG1595	DNA-templated transcription, initiation
LDN82_RS15270	COG1126	abc transporter atp-binding protein
LDN82_RS15275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN82_RS15280	COG0765	amino acid transport
LDN82_RS15285	COG0765	amino acid transport
LDN82_RS15290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDN82_RS15295	COG2171	N-acyltransferase activity
LDN82_RS15310	COG3226	Transcriptional regulator
LDN82_RS15315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LDN82_RS15345	COG1217	gtp-binding protein TYPA
LDN82_RS15360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN82_RS15365	COG0601	transmembrane transport
LDN82_RS15380	COG0012	GTP binding
LDN82_RS15385	COG1322	Protein conserved in bacteria
LDN82_RS15390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LDN82_RS15400	COG1570	exodeoxyribonuclease VII activity
LDN82_RS15405	COG1722	exodeoxyribonuclease VII activity
LDN82_RS15410	COG2326	polyphosphate kinase activity
LDN82_RS15430	COG1174	glycine betaine transport
LDN82_RS15440	COG1162	GTPase activity
LDN82_RS15460	COG2971	BadF BadG BcrA BcrD
LDN82_RS15470	COG0583	DNA-binding transcription factor activity
LDN82_RS15475	COG2814	Major facilitator Superfamily
LDN82_RS15500	COG0598	Magnesium transport protein CorA
LDN82_RS15510	COG1528	Iron-storage protein
LDN82_RS15515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDN82_RS15520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDN82_RS15530	COG2824	Alkylphosphonate utilization operon protein PhnA
LDN82_RS15535	COG1278	Cold shock
LDN82_RS15560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LDN82_RS15565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LDN82_RS15585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDN82_RS15585	COG0519	Catalyzes the synthesis of GMP from XMP
LDN82_RS15605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDN82_RS15610	COG0516	GMP reductase activity
LDN82_RS15615	COG1132	(ABC) transporter
LDN82_RS15635	COG2072	flavoprotein involved in K transport
LDN82_RS15645	COG2197	response regulator
LDN82_RS15650	COG0459	protein refolding
LDN82_RS15655	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LDN82_RS15670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDN82_RS15675	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LDN82_RS15685	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LDN82_RS15690	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LDN82_RS15695	COG0456	acetyltransferase
LDN82_RS15705	COG0802	atpase or kinase
LDN82_RS15710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDN82_RS15730	COG0438	transferase activity, transferring glycosyl groups
LDN82_RS15735	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LDN82_RS15745	COG0667	Aldo Keto reductase
LDN82_RS15770	COG0736	holo-[acyl-carrier-protein] synthase activity
LDN82_RS15780	COG1072	(Pantothenic acid kinase))
LDN82_RS15790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDN82_RS15795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LDN82_RS15800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LDN82_RS15830	COG0455	bacterial-type flagellum organization
LDN82_RS15850	COG0101	tRNA pseudouridine synthase activity
LDN82_RS15855	COG0203	ribosomal protein L17
LDN82_RS15860	COG0202	RNA polymerase activity
LDN82_RS15865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LDN82_RS15870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LDN82_RS15875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LDN82_RS15880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LDN82_RS15885	COG3191	aminopeptidase activity
LDN82_RS15890	COG0024	Methionine aminopeptidase
LDN82_RS15900	COG0318	PFAM AMP-dependent synthetase and ligase
LDN82_RS15905	COG2124	cytochrome p450
LDN82_RS15915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDN82_RS15920	COG0563	adenylate kinase activity
LDN82_RS15930	COG0200	Binds to the 23S rRNA
LDN82_RS15935	COG1841	ribosomal large subunit assembly
LDN82_RS15940	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LDN82_RS15950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LDN82_RS15955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LDN82_RS15960	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LDN82_RS15965	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LDN82_RS15970	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LDN82_RS15975	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LDN82_RS15985	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LDN82_RS15990	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LDN82_RS15995	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LDN82_RS16000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LDN82_RS16005	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LDN82_RS16010	COG0089	rRNA binding
LDN82_RS16015	COG0088	Forms part of the polypeptide exit tunnel
LDN82_RS16020	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LDN82_RS16025	COG0051	transcription antitermination factor activity, RNA binding
LDN82_RS16040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDN82_RS16045	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LDN82_RS16050	COG0049	tRNA binding
LDN82_RS16055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LDN82_RS16060	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LDN82_RS16065	COG0085	RNA polymerase activity
LDN82_RS16070	COG0183	Belongs to the thiolase family
LDN82_RS16075	COG0442	prolyl-tRNA aminoacylation
LDN82_RS16080	COG0222	ribosome binding
LDN82_RS16085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LDN82_RS16100	COG0081	regulation of translation
LDN82_RS16105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LDN82_RS16115	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDN82_RS16125	COG0436	Aminotransferase
LDN82_RS16130	COG2197	response regulator
LDN82_RS16175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDN82_RS16185	COG3485	protocatechuate 3,4-dioxygenase
LDN82_RS16195	COG0745	RESPONSE REGULATOR receiver
LDN82_RS16200	COG0456	acetyltransferase
LDN82_RS16205	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LDN82_RS16215	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LDN82_RS16220	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LDN82_RS16230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDN82_RS16250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LDN82_RS16255	COG2030	dehydratase
LDN82_RS16260	COG2030	dehydratase
LDN82_RS16295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDN82_RS16305	COG4989	oxidoreductase activity
LDN82_RS16310	COG0366	Alpha amylase catalytic
LDN82_RS16315	COG0395	ABC-type sugar transport system, permease component
LDN82_RS16320	COG1175	transmembrane transport
LDN82_RS16330	COG1846	Transcriptional regulator
LDN82_RS16330	COG1940	carbohydrate kinase activity
LDN82_RS16355	COG1652	LysM domain
LDN82_RS16355	COG2823	Periplasmic or secreted lipoprotein
LDN82_RS16385	COG0754	glutathionylspermidine amidase activity
LDN82_RS16395	COG5650	phosphatidylinositol metabolic process
LDN82_RS16415	COG5650	phosphatidylinositol metabolic process
LDN82_RS16445	COG0318	PFAM AMP-dependent synthetase and ligase
LDN82_RS16455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDN82_RS16465	COG1309	transcriptional regulator
LDN82_RS16470	COG1131	(ABC) transporter
LDN82_RS16490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LDN82_RS16505	COG1666	GTP binding
LDN82_RS16510	COG0672	)-iron permease
LDN82_RS16520	COG2837	iron assimilation
LDN82_RS16530	COG0501	Belongs to the peptidase M48B family
LDN82_RS16560	COG0531	amino acid
LDN82_RS16605	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS16610	COG3835	regulator
LDN82_RS16615	COG2807	transmembrane transport
LDN82_RS16620	COG2186	Transcriptional regulator
LDN82_RS16625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDN82_RS16625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDN82_RS16635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDN82_RS16635	COG1648	precorrin-2 dehydrogenase activity
LDN82_RS16640	COG2066	Belongs to the glutaminase family
LDN82_RS16670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDN82_RS16675	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LDN82_RS16685	COG2040	homocysteine
LDN82_RS16705	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDN82_RS16715	COG2860	membrane
LDN82_RS16725	COG0142	geranyltranstransferase activity
LDN82_RS16735	COG2226	methyltransferase
LDN82_RS16740	COG1169	isochorismate synthase
LDN82_RS16750	COG0765	amino acid transport
LDN82_RS16760	COG2186	Transcriptional regulator
LDN82_RS16765	COG1850	ribulose-bisphosphate carboxylase activity
LDN82_RS16775	COG1063	alcohol dehydrogenase
LDN82_RS16785	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LDN82_RS16790	COG2801	Transposase and inactivated derivatives
LDN82_RS16805	COG4948	Mandelate Racemase Muconate Lactonizing
LDN82_RS16825	COG1609	Transcriptional regulator
LDN82_RS16835	COG0395	ABC-type sugar transport system, permease component
LDN82_RS16840	COG1175	transmembrane transport
LDN82_RS16850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDN82_RS16920	COG1404	Belongs to the peptidase S8 family
LDN82_RS16935	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN82_RS16940	COG0022	dehydrogenase e1 component
LDN82_RS16965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LDN82_RS16995	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LDN82_RS17005	COG1134	teichoic acid transport
LDN82_RS17010	COG1682	transport, permease protein
LDN82_RS17015	COG0438	transferase activity, transferring glycosyl groups
LDN82_RS17035	COG1316	TRANSCRIPTIONal
LDN82_RS17040	COG1045	serine acetyltransferase
LDN82_RS17075	COG0489	protein tyrosine kinase activity
LDN82_RS17080	COG0438	transferase activity, transferring glycosyl groups
LDN82_RS17090	COG0438	transferase activity, transferring glycosyl groups
LDN82_RS17100	COG0438	transferase activity, transferring glycosyl groups
LDN82_RS17110	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LDN82_RS17130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LDN82_RS17170	COG2828	Protein conserved in bacteria
LDN82_RS17175	COG0583	DNA-binding transcription factor activity
LDN82_RS17180	COG0671	phosphoesterase, PA-phosphatase related
LDN82_RS17200	COG5002	protein histidine kinase activity
LDN82_RS17205	COG0745	RESPONSE REGULATOR receiver
LDN82_RS17230	COG2894	cell division
LDN82_RS17260	COG5002	protein histidine kinase activity
LDN82_RS17270	COG2837	iron assimilation
LDN82_RS17285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN82_RS17290	COG0765	amino acid transport
LDN82_RS17315	COG0667	Aldo Keto reductase
LDN82_RS17320	COG1609	Transcriptional regulator
LDN82_RS17345	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LDN82_RS17350	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LDN82_RS17355	COG1846	Transcriptional regulator
LDN82_RS17380	COG0028	Belongs to the TPP enzyme family
LDN82_RS17390	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS17395	COG2267	carboxylic ester hydrolase activity
LDN82_RS17415	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS17430	COG2080	2 iron, 2 sulfur cluster binding
LDN82_RS17440	COG2175	clavaminate synthase activity
LDN82_RS17445	COG0477	Major facilitator Superfamily
LDN82_RS17465	COG3842	ATPase activity
LDN82_RS17475	COG1228	amidohydrolase
LDN82_RS17485	COG1024	Enoyl-CoA hydratase
LDN82_RS17490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDN82_RS17495	COG2151	metal-sulfur cluster biosynthetic enzyme
LDN82_RS17500	COG3396	Phenylacetate-CoA oxygenase
LDN82_RS17505	COG3460	Phenylacetate-CoA oxygenase
LDN82_RS17510	COG3396	Phenylacetate-CoA oxygenase
LDN82_RS17520	COG1388	LysM domain
LDN82_RS17520	COG3942	CHAP domain
LDN82_RS17530	COG0784	Response regulator, receiver
LDN82_RS17530	COG5002	protein histidine kinase activity
LDN82_RS17530	COG2205	protein histidine kinase activity
LDN82_RS17535	COG3706	GGDEF domain
LDN82_RS17535	COG5001	Diguanylate cyclase
LDN82_RS17535	COG2203	Gaf domain
LDN82_RS17535	COG4251	negative regulation of phosphorylation
LDN82_RS17585	COG4106	trans-aconitate 2-methyltransferase activity
LDN82_RS17595	COG5002	protein histidine kinase activity
LDN82_RS17620	COG2050	protein possibly involved in aromatic compounds catabolism
LDN82_RS17635	COG3663	DNA glycosylase
LDN82_RS17650	COG2801	Transposase and inactivated derivatives
LDN82_RS17655	COG0477	Major facilitator Superfamily
LDN82_RS17660	COG3119	arylsulfatase activity
LDN82_RS17670	COG1609	Transcriptional regulator
LDN82_RS17675	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS17675	COG2030	dehydratase
LDN82_RS17685	COG1609	Transcriptional regulator
LDN82_RS17700	COG0395	ABC-type sugar transport system, permease component
LDN82_RS17710	COG0673	inositol 2-dehydrogenase activity
LDN82_RS17715	COG0673	inositol 2-dehydrogenase activity
LDN82_RS17735	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDN82_RS17740	COG1024	Enoyl-CoA hydratase
LDN82_RS17745	COG0183	Belongs to the thiolase family
LDN82_RS17760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDN82_RS17770	COG2146	nitrite reductase [NAD(P)H] activity
LDN82_RS17775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDN82_RS17785	COG0488	(ABC) transporter
LDN82_RS17790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDN82_RS17795	COG1121	(ABC) transporter
LDN82_RS17800	COG0803	Belongs to the bacterial solute-binding protein 9 family
LDN82_RS17805	COG1266	CAAX protease self-immunity
LDN82_RS17810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LDN82_RS17840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDN82_RS17850	COG0785	Cytochrome C biogenesis protein
LDN82_RS17860	COG0406	alpha-ribazole phosphatase activity
LDN82_RS17880	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LDN82_RS17910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDN82_RS17915	COG3458	cephalosporin-C deacetylase activity
LDN82_RS17930	COG0395	ABC-type sugar transport system, permease component
LDN82_RS17935	COG4209	transmembrane transport
LDN82_RS17940	COG1653	transport
LDN82_RS17945	COG5578	integral membrane protein
LDN82_RS17955	COG3415	Transposase
LDN82_RS17955	COG2801	Transposase and inactivated derivatives
LDN82_RS17960	COG2814	Major facilitator Superfamily
LDN82_RS17970	COG0395	ABC-type sugar transport system, permease component
LDN82_RS17975	COG1175	transmembrane transport
LDN82_RS17995	COG0395	ABC-type sugar transport system, permease component
LDN82_RS18000	COG1175	transmembrane transport
LDN82_RS18025	COG4948	Mandelate Racemase Muconate Lactonizing
LDN82_RS18030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDN82_RS18040	COG0673	inositol 2-dehydrogenase activity
LDN82_RS18045	COG1609	Transcriptional regulator
LDN82_RS18060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LDN82_RS18065	COG0640	Transcriptional regulator
LDN82_RS18075	COG0123	including yeast histone deacetylase and acetoin utilization protein
LDN82_RS18085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDN82_RS18090	COG0569	domain protein
LDN82_RS18095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDN82_RS18100	COG1082	Xylose isomerase domain protein TIM barrel
LDN82_RS18105	COG0248	Ppx GppA phosphatase
LDN82_RS18115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDN82_RS18115	COG1754	DNA topoisomerase type I activity
LDN82_RS18125	COG2890	protein-(glutamine-N5) methyltransferase activity
LDN82_RS18140	COG1054	Belongs to the UPF0176 family
LDN82_RS18150	COG1111	helicase
LDN82_RS18150	COG1205	dead DEAH box helicase
LDN82_RS18155	COG3415	Transposase
LDN82_RS18155	COG2801	Transposase and inactivated derivatives
LDN82_RS18225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDN82_RS18230	COG1349	DNA-binding transcription factor activity
LDN82_RS18235	COG0577	efflux transmembrane transporter activity
LDN82_RS18235	COG1136	(ABC) transporter
LDN82_RS18245	COG1609	Transcriptional regulator
LDN82_RS18255	COG1175	transmembrane transport
LDN82_RS18260	COG0395	ABC-type sugar transport system, permease component
LDN82_RS18305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDN82_RS18310	COG1408	metallophosphoesterase
LDN82_RS18315	COG1132	(ABC) transporter
LDN82_RS18320	COG1132	(ABC) transporter
LDN82_RS18340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LDN82_RS18345	COG0151	Belongs to the GarS family
LDN82_RS18360	COG1301	dicarboxylic acid transport
LDN82_RS18365	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS18375	COG1953	Uracil, thiamine, allantoin
LDN82_RS18380	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LDN82_RS18395	COG0454	-acetyltransferase
LDN82_RS18400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LDN82_RS18410	COG3608	succinylglutamate desuccinylase aspartoacylase
LDN82_RS18410	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LDN82_RS18415	COG2252	PERMEase
LDN82_RS18420	COG0590	tRNA wobble adenosine to inosine editing
LDN82_RS18445	COG2233	PERMEase
LDN82_RS18455	COG1414	Transcriptional regulator
LDN82_RS18465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LDN82_RS18475	COG3257	ureidoglycine aminohydrolase activity
LDN82_RS18510	COG2271	Major facilitator Superfamily
LDN82_RS18525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDN82_RS18525	COG4499	WXG100 protein secretion system (Wss), protein YukC
LDN82_RS18555	COG0659	secondary active sulfate transmembrane transporter activity
LDN82_RS18565	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LDN82_RS18575	COG0563	adenylate kinase activity
LDN82_RS18600	COG0477	Major facilitator Superfamily
LDN82_RS18610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDN82_RS18620	COG3401	FG-GAP repeat protein
LDN82_RS18655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDN82_RS18685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LDN82_RS18700	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LDN82_RS18725	COG2267	carboxylic ester hydrolase activity
LDN82_RS18775	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LDN82_RS18780	COG0583	DNA-binding transcription factor activity
LDN82_RS18790	COG1301	dicarboxylic acid transport
LDN82_RS18795	COG1929	Belongs to the glycerate kinase type-1 family
LDN82_RS18805	COG0405	Gamma-glutamyltransferase
LDN82_RS18810	COG0494	nUDIX hydrolase
LDN82_RS18860	COG1454	alcohol dehydrogenase
LDN82_RS18865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDN82_RS18895	COG0477	Major facilitator Superfamily
LDN82_RS18900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDN82_RS18910	COG0583	DNA-binding transcription factor activity
LDN82_RS18940	COG0673	inositol 2-dehydrogenase activity
LDN82_RS18950	COG0673	inositol 2-dehydrogenase activity
LDN82_RS18965	COG1653	transport
LDN82_RS18970	COG1609	Transcriptional regulator
LDN82_RS18995	COG3622	Belongs to the hyi family
LDN82_RS19000	COG2084	Dehydrogenase
LDN82_RS19005	COG3960	tartronate-semialdehyde synthase activity
LDN82_RS19010	COG1929	Belongs to the glycerate kinase type-1 family
LDN82_RS19015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDN82_RS19020	COG0745	RESPONSE REGULATOR receiver
LDN82_RS19030	COG0745	RESPONSE REGULATOR receiver
LDN82_RS19040	COG1366	Belongs to the anti-sigma-factor antagonist family
LDN82_RS19065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LDN82_RS19070	COG0671	phosphoesterase, PA-phosphatase related
LDN82_RS19095	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LDN82_RS19120	COG0542	response to heat
LDN82_RS19145	COG3585	molybdate ion transport
LDN82_RS19165	COG3304	Inner membrane component domain
LDN82_RS19175	COG0135	phosphoribosylanthranilate isomerase activity
LDN82_RS19195	COG0667	Aldo Keto reductase
LDN82_RS19210	COG2814	Major facilitator Superfamily
LDN82_RS19225	COG0500	methyltransferase
LDN82_RS19235	COG1473	amidohydrolase
LDN82_RS19240	COG0477	Major facilitator Superfamily
LDN82_RS19245	COG2807	transmembrane transport
LDN82_RS19250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LDN82_RS19290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LDN82_RS19335	COG0789	Transcriptional regulator
LDN82_RS19340	COG0484	heat shock protein binding
LDN82_RS19345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LDN82_RS19350	COG0443	Heat shock 70 kDa protein
LDN82_RS19360	COG3739	integral membrane protein
LDN82_RS19435	COG0436	Aminotransferase
LDN82_RS19440	COG1063	alcohol dehydrogenase
LDN82_RS19445	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LDN82_RS19460	COG0531	amino acid
LDN82_RS19475	COG3226	Transcriptional regulator
LDN82_RS19480	COG1280	lysine exporter protein (LysE YggA)
LDN82_RS19485	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS19500	COG0492	ferredoxin-NADP+ reductase activity
LDN82_RS19505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDN82_RS19530	COG0574	Belongs to the PEP-utilizing enzyme family
LDN82_RS19530	COG3848	Pyruvate phosphate dikinase
LDN82_RS19535	COG2409	Drug exporters of the RND superfamily
LDN82_RS19545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDN82_RS19550	COG3795	YCII-related domain
LDN82_RS19555	COG4941	Belongs to the sigma-70 factor family
LDN82_RS19560	COG0667	Aldo Keto reductase
LDN82_RS19580	COG1280	lysine exporter protein (LysE YggA)
LDN82_RS19585	COG1609	Transcriptional regulator
LDN82_RS19590	COG1957	nucleoside hydrolase
LDN82_RS19595	COG0477	Major facilitator Superfamily
LDN82_RS19600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDN82_RS19610	COG1309	transcriptional regulator
LDN82_RS19615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDN82_RS19625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDN82_RS19635	COG0833	amino acid
LDN82_RS19640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LDN82_RS19645	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LDN82_RS19665	COG2986	histidine ammonia-lyase
LDN82_RS19695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LDN82_RS19700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LDN82_RS19720	COG1122	ATPase activity
LDN82_RS19725	COG4721	ABC-type cobalt transport system, permease component
LDN82_RS19740	COG1320	monovalent cation:proton antiporter activity
LDN82_RS19745	COG2212	antiporter activity
LDN82_RS19750	COG1863	multisubunit Na H antiporter MnhE subunit
LDN82_RS19755	COG0651	ATP synthesis coupled electron transport
LDN82_RS19760	COG1006	Multisubunit Na H antiporter MnhC subunit
LDN82_RS19765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LDN82_RS19765	COG2111	Na H antiporter
LDN82_RS19780	COG0475	glutathione-regulated potassium exporter activity
LDN82_RS19785	COG0717	Belongs to the dCTP deaminase family
LDN82_RS19830	COG0583	DNA-binding transcription factor activity
LDN82_RS19845	COG0640	Transcriptional regulator
LDN82_RS19855	COG1609	Transcriptional regulator
LDN82_RS19860	COG0673	inositol 2-dehydrogenase activity
LDN82_RS19885	COG1295	ribonuclease BN
LDN82_RS19895	COG2115	Belongs to the xylose isomerase family
LDN82_RS19900	COG1070	Carbohydrate kinase
LDN82_RS19905	COG1609	Transcriptional regulator
LDN82_RS19920	COG2160	L-arabinose isomerase activity
LDN82_RS19925	COG2017	converts alpha-aldose to the beta-anomer
LDN82_RS19935	COG3254	rhamnose metabolic process
LDN82_RS19945	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS19945	COG3347	Dehydrogenase
LDN82_RS19950	COG1070	Carbohydrate kinase
LDN82_RS19960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LDN82_RS19995	COG3387	PFAM Glycoside hydrolase 15-related
LDN82_RS20000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN82_RS20005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN82_RS20010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LDN82_RS20045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDN82_RS20060	COG1126	abc transporter atp-binding protein
LDN82_RS20065	COG0765	amino acid transport
LDN82_RS20080	COG0433	COG0433 Predicted ATPase
LDN82_RS20100	COG0776	regulation of translation
LDN82_RS20150	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LDN82_RS20155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LDN82_RS20160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LDN82_RS20205	COG1120	ATPase activity
LDN82_RS20210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDN82_RS20215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDN82_RS20255	COG3012	SEC-C Motif Domain Protein
LDN82_RS20270	COG0667	Aldo Keto reductase
LDN82_RS20320	COG2186	Transcriptional regulator
LDN82_RS20330	COG1027	Aspartate ammonia-lyase
LDN82_RS20340	COG2186	Transcriptional regulator
LDN82_RS20345	COG3618	amidohydrolase
LDN82_RS20355	COG3254	rhamnose metabolic process
LDN82_RS20370	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDN82_RS20380	COG4948	Mandelate Racemase Muconate Lactonizing
LDN82_RS20390	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS20425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LDN82_RS20450	COG4221	oxidoreductase activity
LDN82_RS20460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LDN82_RS20465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDN82_RS20475	COG1522	sequence-specific DNA binding
LDN82_RS20480	COG1280	lysine exporter protein (LysE YggA)
LDN82_RS20490	COG0640	Transcriptional regulator
LDN82_RS20505	COG1414	Transcriptional regulator
LDN82_RS20515	COG0477	Major facilitator Superfamily
LDN82_RS20530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDN82_RS20555	COG1760	l-serine dehydratase
LDN82_RS20585	COG0281	malic enzyme
LDN82_RS20590	COG1309	transcriptional regulator
LDN82_RS20650	COG0477	Major facilitator Superfamily
LDN82_RS20655	COG2986	histidine ammonia-lyase
LDN82_RS20660	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LDN82_RS20675	COG1174	glycine betaine transport
LDN82_RS20690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDN82_RS20700	COG0477	Major facilitator Superfamily
LDN82_RS20705	COG2814	Major facilitator Superfamily
LDN82_RS20740	COG1113	amino acid transport
LDN82_RS20745	COG0246	Mannitol dehydrogenase
LDN82_RS20750	COG2213	PTS system mannitol-specific
LDN82_RS20750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDN82_RS20760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDN82_RS20765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDN82_RS20780	COG4608	Belongs to the ABC transporter superfamily
LDN82_RS20785	COG0444	Belongs to the ABC transporter superfamily
LDN82_RS20790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDN82_RS20795	COG0601	transmembrane transport
LDN82_RS20800	COG0747	negative chemotaxis
LDN82_RS20825	COG2267	carboxylic ester hydrolase activity
LDN82_RS20835	COG1793	dna ligase
LDN82_RS20860	COG0686	Belongs to the AlaDH PNT family
LDN82_RS20880	COG0673	inositol 2-dehydrogenase activity
LDN82_RS20905	COG1309	transcriptional regulator
LDN82_RS20935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDN82_RS20955	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDN82_RS20960	COG0022	dehydrogenase e1 component
LDN82_RS20970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDN82_RS20975	COG1950	PFAM Membrane protein of
LDN82_RS20990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LDN82_RS20995	COG0406	alpha-ribazole phosphatase activity
LDN82_RS21005	COG1607	acyl-coa hydrolase
LDN82_RS21010	COG4221	oxidoreductase activity
LDN82_RS21015	COG0477	Major facilitator Superfamily
LDN82_RS21020	COG1984	allophanate hydrolase subunit 2
LDN82_RS21025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LDN82_RS21030	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LDN82_RS21035	COG0583	DNA-binding transcription factor activity
LDN82_RS21045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDN82_RS21050	COG0436	Aminotransferase
LDN82_RS21070	COG3971	2-oxopent-4-enoate hydratase activity
LDN82_RS21085	COG1802	Transcriptional regulator
LDN82_RS21090	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDN82_RS21115	COG2261	transglycosylase associated protein
LDN82_RS21130	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS21150	COG1609	Transcriptional regulator
LDN82_RS21155	COG1653	transport
LDN82_RS21165	COG0395	ABC-type sugar transport system, permease component
LDN82_RS21190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDN82_RS21205	COG0515	serine threonine protein kinase
LDN82_RS21240	COG0604	alcohol dehydrogenase
LDN82_RS21250	COG3387	PFAM Glycoside hydrolase 15-related
LDN82_RS21305	COG2814	Major facilitator Superfamily
LDN82_RS21325	COG0243	molybdopterin cofactor binding
LDN82_RS21385	COG0515	serine threonine protein kinase
LDN82_RS21385	COG2815	serine threonine protein kinase
LDN82_RS21390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LDN82_RS21395	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LDN82_RS21400	COG1760	l-serine dehydratase
LDN82_RS21405	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDN82_RS21410	COG0509	glycine decarboxylation via glycine cleavage system
LDN82_RS21415	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDN82_RS21420	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDN82_RS21420	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDN82_RS21435	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LDN82_RS21450	COG1970	mechanosensitive ion channel activity
LDN82_RS21460	COG2271	Major facilitator Superfamily
LDN82_RS21465	COG1802	Transcriptional regulator
LDN82_RS21525	COG0546	phosphoglycolate phosphatase activity
LDN82_RS21550	COG2814	Major facilitator Superfamily
LDN82_RS21580	COG0251	oxidation-reduction process
LDN82_RS21590	COG1414	Transcriptional regulator
LDN82_RS21595	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LDN82_RS21605	COG0183	Belongs to the thiolase family
LDN82_RS21610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LDN82_RS21630	COG3485	protocatechuate 3,4-dioxygenase
LDN82_RS21635	COG1082	Xylose isomerase domain protein TIM barrel
LDN82_RS21635	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LDN82_RS21640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDN82_RS21645	COG1414	Transcriptional regulator
LDN82_RS21665	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LDN82_RS21685	COG0646	methionine synthase
LDN82_RS21685	COG1410	methionine synthase
LDN82_RS21690	COG3845	ABC transporter
LDN82_RS21710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LDN82_RS21715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN82_RS21735	COG0251	oxidation-reduction process
LDN82_RS21745	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS21750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDN82_RS21755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDN82_RS21790	COG2610	gluconate transmembrane transporter activity
LDN82_RS21800	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LDN82_RS21815	COG1414	Transcriptional regulator
LDN82_RS21880	COG1937	Protein conserved in bacteria
LDN82_RS21905	COG0697	spore germination
LDN82_RS21925	COG0534	Mate efflux family protein
LDN82_RS21935	COG2259	Doxx family
LDN82_RS21945	COG1607	acyl-coa hydrolase
LDN82_RS21955	COG1609	Transcriptional regulator
LDN82_RS21975	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDN82_RS21985	COG4213	ABC transporter substrate-binding protein
LDN82_RS21990	COG1609	Transcriptional regulator
LDN82_RS22000	COG0590	tRNA wobble adenosine to inosine editing
LDN82_RS22010	COG4974	Belongs to the 'phage' integrase family
LDN82_RS22040	COG0673	inositol 2-dehydrogenase activity
LDN82_RS22045	COG0673	inositol 2-dehydrogenase activity
LDN82_RS22055	COG2723	6-phospho-beta-galactosidase activity
LDN82_RS22060	COG1472	Belongs to the glycosyl hydrolase 3 family
LDN82_RS22065	COG0395	ABC-type sugar transport system, permease component
LDN82_RS22070	COG1175	transmembrane transport
LDN82_RS22125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDN82_RS22135	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS22140	COG1012	belongs to the aldehyde dehydrogenase family
LDN82_RS22170	COG3958	Transketolase
LDN82_RS22175	COG3959	Transketolase, thiamine diphosphate binding domain
LDN82_RS22190	COG1028	Short-chain dehydrogenase reductase Sdr
LDN82_RS22195	COG2376	Dihydroxyacetone kinase
LDN82_RS22200	COG0698	ribose 5-phosphate isomerase
LDN82_RS22210	COG0305	Participates in initiation and elongation during chromosome replication
LDN82_RS22245	COG2610	gluconate transmembrane transporter activity
LDN82_RS22250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDN82_RS22255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDN82_RS22265	COG1929	Belongs to the glycerate kinase type-1 family
LDN82_RS22290	COG1414	Transcriptional regulator
LDN82_RS22305	COG0359	binds to the 23S rRNA
LDN82_RS22310	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LDN82_RS22320	COG0360	Binds together with S18 to 16S ribosomal RNA
LDN82_RS22325	COG1742	UPF0060 membrane protein
LDN82_RS22345	COG1113	amino acid transport
LDN82_RS22350	COG1362	aminopeptidase activity
LDN82_RS22380	COG0833	amino acid
LDN82_RS22385	COG2197	response regulator
LDN82_RS22390	COG4585	Histidine kinase
LDN82_RS22400	COG1131	(ABC) transporter
LDN82_RS22405	COG1597	lipid kinase activity
LDN82_RS22415	COG0738	Major facilitator superfamily
LDN82_RS22425	COG0488	(ABC) transporter
LDN82_RS22435	COG0768	penicillin binding
LDN82_RS22440	COG1501	Belongs to the glycosyl hydrolase 31 family
LDN82_RS22445	COG2197	response regulator
LDN82_RS22460	COG1136	(ABC) transporter
LDN82_RS22465	COG1733	regulation of RNA biosynthetic process
LDN82_RS22470	COG2910	NAD(P)H-binding
LDN82_RS22490	COG0406	alpha-ribazole phosphatase activity
LDN82_RS22495	COG0617	tRNA 3'-terminal CCA addition
LDN82_RS22515	COG0492	ferredoxin-NADP+ reductase activity
LDN82_RS22520	COG3118	belongs to the thioredoxin family
LDN82_RS22530	COG1192	Involved in chromosome partitioning
LDN82_RS22535	COG0357	Ribosomal RNA small subunit methyltransferase G
LDN82_RS22545	COG0706	membrane insertase activity
LDN82_RS22550	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LDN82_RS22555	COG0594	ribonuclease P activity
LDN82_RS22560	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LDN82_RS22575	COG2814	Major facilitator Superfamily