locus-tag	class	description
CGK93_RS00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CGK93_RS00015	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CGK93_RS00020	COG0592	DNA-directed DNA polymerase activity
CGK93_RS00025	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CGK93_RS00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CGK93_RS00035	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CGK93_RS00040	COG0187	DNA topoisomerase II activity
CGK93_RS00050	COG3266	domain, Protein
CGK93_RS00075	COG1215	transferase activity, transferring glycosyl groups
CGK93_RS00090	COG0705	Rhomboid family
CGK93_RS00100	COG2818	Glycosylase
CGK93_RS00110	COG2169	Transcriptional regulator
CGK93_RS00110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGK93_RS00130	COG3764	Sortase (surface protein transpeptidase)
CGK93_RS00140	COG0515	serine threonine protein kinase
CGK93_RS00145	COG0515	serine threonine protein kinase
CGK93_RS00150	COG0768	penicillin binding
CGK93_RS00165	COG1716	ATPase activity
CGK93_RS00170	COG1716	ATPase activity
CGK93_RS00180	COG2188	Transcriptional regulator
CGK93_RS00190	COG2197	response regulator
CGK93_RS00195	COG4585	Histidine kinase
CGK93_RS00235	COG1505	serine-type exopeptidase activity
CGK93_RS00265	COG1132	(ABC) transporter
CGK93_RS00270	COG1132	(ABC) transporter
CGK93_RS00275	COG1609	Transcriptional regulator
CGK93_RS00290	COG1120	ATPase activity
CGK93_RS00305	COG0346	lactoylglutathione lyase activity
CGK93_RS00320	COG2186	Transcriptional regulator
CGK93_RS00325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CGK93_RS00335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CGK93_RS00340	COG4770	biotin carboxylase activity
CGK93_RS00345	COG0277	FAD linked oxidase domain protein
CGK93_RS00350	COG1609	Transcriptional regulator
CGK93_RS00355	COG0385	Bile acid
CGK93_RS00360	COG0659	secondary active sulfate transmembrane transporter activity
CGK93_RS00380	COG0435	Glutathione S-transferase
CGK93_RS00385	COG0561	phosphatase activity
CGK93_RS00420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_RS00425	COG1929	Belongs to the glycerate kinase type-1 family
CGK93_RS00455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGK93_RS00510	COG0506	proline dehydrogenase activity
CGK93_RS00535	COG1309	transcriptional regulator
CGK93_RS00540	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS00545	COG1309	transcriptional regulator
CGK93_RS00555	COG0693	protein deglycase activity
CGK93_RS00565	COG3655	Transcriptional regulator
CGK93_RS00580	COG2723	6-phospho-beta-galactosidase activity
CGK93_RS00585	COG0395	ABC-type sugar transport system, permease component
CGK93_RS00610	COG1131	(ABC) transporter
CGK93_RS00620	COG2197	response regulator
CGK93_RS00625	COG4585	Histidine kinase
CGK93_RS00630	COG4585	Histidine kinase
CGK93_RS00640	COG2233	PERMEase
CGK93_RS00645	COG0778	Nitroreductase
CGK93_RS00670	COG3104	oligopeptide transport
CGK93_RS00680	COG3340	Belongs to the peptidase S51 family
CGK93_RS00685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGK93_RS00685	COG0425	Belongs to the sulfur carrier protein TusA family
CGK93_RS00690	COG0077	Prephenate dehydratase
CGK93_RS00700	COG1597	lipid kinase activity
CGK93_RS00705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CGK93_RS00725	COG3973	AAA domain
CGK93_RS00730	COG0561	phosphatase activity
CGK93_RS00750	COG1191	sigma factor activity
CGK93_RS00760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CGK93_RS00765	COG0859	PFAM glycosyl transferase family 9
CGK93_RS00775	COG0438	transferase activity, transferring glycosyl groups
CGK93_RS00780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CGK93_RS00785	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CGK93_RS00785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CGK93_RS00790	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS00800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CGK93_RS00800	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CGK93_RS00860	COG2027	D-alanyl-D-alanine carboxypeptidase
CGK93_RS00870	COG0037	tRNA processing
CGK93_RS00885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGK93_RS00890	COG0302	gtp cyclohydrolase
CGK93_RS00900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CGK93_RS00930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CGK93_RS00935	COG2814	Major facilitator Superfamily
CGK93_RS01010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CGK93_RS01030	COG1506	peptidase
CGK93_RS01030	COG0823	Involved in the tonB-independent uptake of proteins
CGK93_RS01040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CGK93_RS01055	COG1609	Transcriptional regulator
CGK93_RS01055	COG2207	Transcriptional regulator
CGK93_RS01060	COG1335	isochorismatase
CGK93_RS01065	COG2376	Dihydroxyacetone kinase
CGK93_RS01070	COG1461	Dihydroxyacetone kinase
CGK93_RS01075	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CGK93_RS01080	COG3237	CsbD-like
CGK93_RS01105	COG1301	dicarboxylic acid transport
CGK93_RS01115	COG1194	a g-specific adenine glycosylase
CGK93_RS01125	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CGK93_RS01140	COG3665	Urea carboxylase-associated protein
CGK93_RS01170	COG0671	phosphoesterase, PA-phosphatase related
CGK93_RS01195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CGK93_RS01260	COG1609	Transcriptional regulator
CGK93_RS01295	COG0831	urea catabolic process
CGK93_RS01300	COG0832	Belongs to the urease beta subunit family
CGK93_RS01305	COG0804	urea catabolic process
CGK93_RS01310	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CGK93_RS01315	COG0830	nickel cation binding
CGK93_RS01320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CGK93_RS01325	COG0829	nickel cation binding
CGK93_RS01330	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CGK93_RS01340	COG1595	DNA-templated transcription, initiation
CGK93_RS01370	COG0656	L-ascorbic acid biosynthetic process
CGK93_RS01380	COG0667	Aldo Keto reductase
CGK93_RS01385	COG0656	L-ascorbic acid biosynthetic process
CGK93_RS01395	COG3360	Dodecin
CGK93_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS01410	COG0028	Belongs to the TPP enzyme family
CGK93_RS01415	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CGK93_RS01420	COG1233	COG1233 Phytoene dehydrogenase and related
CGK93_RS01425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGK93_RS01450	COG2186	Transcriptional regulator
CGK93_RS01455	COG2267	carboxylic ester hydrolase activity
CGK93_RS01465	COG2084	Dehydrogenase
CGK93_RS01470	COG2610	gluconate transmembrane transporter activity
CGK93_RS01525	COG0076	glutamate decarboxylase activity
CGK93_RS01530	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CGK93_RS01550	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS01560	COG1289	transmembrane transporter activity
CGK93_RS01575	COG0346	lactoylglutathione lyase activity
CGK93_RS01590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGK93_RS01595	COG0477	Major facilitator Superfamily
CGK93_RS01600	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CGK93_RS01610	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CGK93_RS01640	COG1793	dna ligase
CGK93_RS01640	COG3285	dna ligase
CGK93_RS01645	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CGK93_RS01680	COG3226	Transcriptional regulator
CGK93_RS01690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGK93_RS01690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGK93_RS01690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGK93_RS01700	COG1349	DNA-binding transcription factor activity
CGK93_RS01720	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGK93_RS01745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGK93_RS01765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_RS01770	COG0765	amino acid transport
CGK93_RS01775	COG1126	abc transporter atp-binding protein
CGK93_RS01840	COG1846	Transcriptional regulator
CGK93_RS01865	COG0142	geranyltranstransferase activity
CGK93_RS01870	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CGK93_RS01900	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_RS01915	COG2814	Major facilitator Superfamily
CGK93_RS01920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGK93_RS01925	COG4335	DNA alkylation repair
CGK93_RS01935	COG0129	dihydroxy-acid dehydratase activity
CGK93_RS01950	COG2197	response regulator
CGK93_RS01965	COG5006	permease, DMT superfamily
CGK93_RS01985	COG2066	Belongs to the glutaminase family
CGK93_RS02005	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CGK93_RS02025	COG2733	membrane
CGK93_RS02065	COG4122	O-methyltransferase activity
CGK93_RS02095	COG1132	(ABC) transporter
CGK93_RS02100	COG1132	(ABC) transporter
CGK93_RS02105	COG2207	Transcriptional regulator
CGK93_RS02120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_RS02130	COG1120	ATPase activity
CGK93_RS02135	COG0583	DNA-binding transcription factor activity
CGK93_RS02145	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS02150	COG1733	regulation of RNA biosynthetic process
CGK93_RS02155	COG0702	epimerase
CGK93_RS02175	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CGK93_RS02205	COG0010	Belongs to the arginase family
CGK93_RS02210	COG2252	PERMEase
CGK93_RS02235	COG0574	Belongs to the PEP-utilizing enzyme family
CGK93_RS02235	COG3848	Pyruvate phosphate dikinase
CGK93_RS02250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGK93_RS02285	COG1302	Protein conserved in bacteria
CGK93_RS02330	COG1653	transport
CGK93_RS02335	COG1175	transmembrane transport
CGK93_RS02340	COG0395	ABC-type sugar transport system, permease component
CGK93_RS02345	COG1609	Transcriptional regulator
CGK93_RS02365	COG2197	response regulator
CGK93_RS02370	COG4585	Histidine kinase
CGK93_RS02385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGK93_RS02395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CGK93_RS02415	COG4585	Histidine kinase
CGK93_RS02435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CGK93_RS02450	COG1063	alcohol dehydrogenase
CGK93_RS02460	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGK93_RS02465	COG3404	Formiminotransferase-cyclodeaminase
CGK93_RS02480	COG1802	Transcriptional regulator
CGK93_RS02485	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CGK93_RS02495	COG0583	DNA-binding transcription factor activity
CGK93_RS02520	COG0415	Belongs to the DNA photolyase family
CGK93_RS02530	COG1024	Enoyl-CoA hydratase
CGK93_RS02595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CGK93_RS02600	COG1960	acyl-CoA dehydrogenase activity
CGK93_RS02635	COG1280	lysine exporter protein (LysE YggA)
CGK93_RS02705	COG1621	beta-fructofuranosidase activity
CGK93_RS02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGK93_RS02720	COG0789	Transcriptional regulator
CGK93_RS02735	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_RS02740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CGK93_RS02750	COG0531	amino acid
CGK93_RS02755	COG2186	Transcriptional regulator
CGK93_RS02760	COG3835	regulator
CGK93_RS02765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_RS02770	COG0765	amino acid transport
CGK93_RS02775	COG1126	abc transporter atp-binding protein
CGK93_RS02785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGK93_RS02790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CGK93_RS02795	COG1609	Transcriptional regulator
CGK93_RS02810	COG0747	negative chemotaxis
CGK93_RS02820	COG0444	Belongs to the ABC transporter superfamily
CGK93_RS02825	COG4172	Belongs to the ABC transporter superfamily
CGK93_RS02835	COG0673	inositol 2-dehydrogenase activity
CGK93_RS02840	COG1609	Transcriptional regulator
CGK93_RS02845	COG1904	glucuronate isomerase
CGK93_RS02850	COG0246	Mannitol dehydrogenase
CGK93_RS02855	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_RS02865	COG4213	ABC transporter substrate-binding protein
CGK93_RS02870	COG1129	ABC transporter
CGK93_RS02875	COG4214	carbohydrate transport
CGK93_RS02880	COG1609	Transcriptional regulator
CGK93_RS02885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CGK93_RS02930	COG1120	ATPase activity
CGK93_RS02935	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_RS02940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_RS02945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGK93_RS02980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CGK93_RS02995	COG2814	Major facilitator Superfamily
CGK93_RS03015	COG1309	transcriptional regulator
CGK93_RS03055	COG0583	DNA-binding transcription factor activity
CGK93_RS03060	COG0039	L-malate dehydrogenase activity
CGK93_RS03065	COG0477	Major facilitator Superfamily
CGK93_RS03070	COG2267	carboxylic ester hydrolase activity
CGK93_RS03080	COG3263	regulation of cellular component size
CGK93_RS03110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CGK93_RS03125	COG0765	amino acid transport
CGK93_RS03130	COG1126	abc transporter atp-binding protein
CGK93_RS03135	COG0673	inositol 2-dehydrogenase activity
CGK93_RS03180	COG1832	CoA-binding protein
CGK93_RS03190	COG2315	Protein conserved in bacteria
CGK93_RS03200	COG1653	transport
CGK93_RS03205	COG1175	transmembrane transport
CGK93_RS03210	COG0395	ABC-type sugar transport system, permease component
CGK93_RS03230	COG2368	4-hydroxyphenylacetate
CGK93_RS03270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CGK93_RS03290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGK93_RS03295	COG0047	phosphoribosylformylglycinamidine synthase activity
CGK93_RS03315	COG3546	catalase activity
CGK93_RS03320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGK93_RS03350	COG1846	Transcriptional regulator
CGK93_RS03365	COG1174	glycine betaine transport
CGK93_RS03370	COG0517	IMP dehydrogenase activity
CGK93_RS03370	COG1125	glycine betaine transport
CGK93_RS03375	COG1174	glycine betaine transport
CGK93_RS03380	COG1732	Glycine betaine
CGK93_RS03390	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_RS03395	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_RS03400	COG2084	Dehydrogenase
CGK93_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS03425	COG5416	Lipopolysaccharide assembly protein A domain
CGK93_RS03440	COG2814	Major facilitator Superfamily
CGK93_RS03470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CGK93_RS03485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CGK93_RS03500	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_RS03525	COG0741	lytic transglycosylase activity
CGK93_RS03525	COG1196	nuclear chromosome segregation
CGK93_RS03525	COG0739	heme binding
CGK93_RS03530	COG0386	Belongs to the glutathione peroxidase family
CGK93_RS03535	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CGK93_RS03580	COG1309	transcriptional regulator
CGK93_RS03585	COG1609	Transcriptional regulator
CGK93_RS03590	COG0673	inositol 2-dehydrogenase activity
CGK93_RS03600	COG1609	Transcriptional regulator
CGK93_RS03610	COG1175	transmembrane transport
CGK93_RS03615	COG0395	ABC-type sugar transport system, permease component
CGK93_RS03630	COG0438	transferase activity, transferring glycosyl groups
CGK93_RS03655	COG1621	beta-fructofuranosidase activity
CGK93_RS03660	COG1609	Transcriptional regulator
CGK93_RS03665	COG0395	ABC-type sugar transport system, permease component
CGK93_RS03690	COG1621	beta-fructofuranosidase activity
CGK93_RS03695	COG0589	response to stress
CGK93_RS03715	COG3290	protein histidine kinase activity
CGK93_RS03735	COG0546	phosphoglycolate phosphatase activity
CGK93_RS03750	COG2076	Multidrug Resistance protein
CGK93_RS03755	COG0590	tRNA wobble adenosine to inosine editing
CGK93_RS03760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CGK93_RS03775	COG4702	Belongs to the UPF0303 family
CGK93_RS03795	COG0673	inositol 2-dehydrogenase activity
CGK93_RS03825	COG1476	TRANSCRIPTIONal
CGK93_RS03835	COG1309	transcriptional regulator
CGK93_RS03845	COG0351	phosphomethylpyrimidine kinase
CGK93_RS03855	COG0642	Histidine kinase
CGK93_RS03860	COG0745	RESPONSE REGULATOR receiver
CGK93_RS03865	COG0477	Major facilitator Superfamily
CGK93_RS03870	COG1090	epimerase
CGK93_RS03885	COG0343	queuine tRNA-ribosyltransferase activity
CGK93_RS03925	COG1960	acyl-CoA dehydrogenase activity
CGK93_RS03955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGK93_RS03980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CGK93_RS03990	COG0586	Pfam SNARE associated Golgi protein
CGK93_RS04000	COG0564	pseudouridine synthase activity
CGK93_RS04030	COG2364	Membrane
CGK93_RS04045	COG1215	transferase activity, transferring glycosyl groups
CGK93_RS04055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGK93_RS04060	COG1201	RNA secondary structure unwinding
CGK93_RS04085	COG0515	serine threonine protein kinase
CGK93_RS04160	COG0438	transferase activity, transferring glycosyl groups
CGK93_RS04175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CGK93_RS04200	COG2205	protein histidine kinase activity
CGK93_RS04205	COG0745	RESPONSE REGULATOR receiver
CGK93_RS04215	COG2062	phosphohistidine phosphatase, SixA
CGK93_RS04225	COG0583	DNA-binding transcription factor activity
CGK93_RS04230	COG0697	spore germination
CGK93_RS04245	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CGK93_RS04255	COG0601	transmembrane transport
CGK93_RS04265	COG4172	Belongs to the ABC transporter superfamily
CGK93_RS04270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGK93_RS04280	COG1309	transcriptional regulator
CGK93_RS04285	COG1511	domain protein
CGK93_RS04305	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CGK93_RS04310	COG1940	carbohydrate kinase activity
CGK93_RS04320	COG4608	Belongs to the ABC transporter superfamily
CGK93_RS04325	COG0444	Belongs to the ABC transporter superfamily
CGK93_RS04335	COG0747	negative chemotaxis
CGK93_RS04355	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CGK93_RS04380	COG0514	ATP-dependent DNA helicase (RecQ)
CGK93_RS04385	COG2814	Major facilitator Superfamily
CGK93_RS04395	COG1505	serine-type exopeptidase activity
CGK93_RS04425	COG0604	alcohol dehydrogenase
CGK93_RS04425	COG3321	synthase
CGK93_RS04425	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS04435	COG1966	Carbon starvation protein
CGK93_RS04455	COG0656	L-ascorbic acid biosynthetic process
CGK93_RS04465	COG0154	amidase activity
CGK93_RS04505	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CGK93_RS04510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CGK93_RS04530	COG0588	phosphoglycerate mutase activity
CGK93_RS04540	COG5002	protein histidine kinase activity
CGK93_RS04560	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CGK93_RS04565	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CGK93_RS04575	COG0215	cysteine-tRNA ligase activity
CGK93_RS04610	COG0366	Alpha amylase catalytic
CGK93_RS04620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CGK93_RS04650	COG1609	Transcriptional regulator
CGK93_RS04670	COG3833	ABC-type maltose transport systems, permease component
CGK93_RS04675	COG0366	Alpha amylase catalytic
CGK93_RS04680	COG0277	FAD linked oxidase domain protein
CGK93_RS04695	COG0402	S-adenosylhomocysteine deaminase activity
CGK93_RS04715	COG3842	ATPase activity
CGK93_RS04740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CGK93_RS04750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_RS04770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CGK93_RS04775	COG2814	Major facilitator Superfamily
CGK93_RS04870	COG3201	nicotinamide mononucleotide transporter
CGK93_RS04885	COG0586	Pfam SNARE associated Golgi protein
CGK93_RS04890	COG1609	Transcriptional regulator
CGK93_RS04895	COG0395	ABC-type sugar transport system, permease component
CGK93_RS04900	COG1175	transmembrane transport
CGK93_RS04915	COG1621	beta-fructofuranosidase activity
CGK93_RS04925	COG0514	ATP-dependent DNA helicase (RecQ)
CGK93_RS04930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CGK93_RS04980	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS04990	COG1960	acyl-CoA dehydrogenase activity
CGK93_RS05015	COG0579	oxidoreductase
CGK93_RS05045	COG2957	Belongs to the agmatine deiminase family
CGK93_RS05055	COG0024	Methionine aminopeptidase
CGK93_RS05070	COG0492	ferredoxin-NADP+ reductase activity
CGK93_RS05090	COG0477	Major facilitator Superfamily
CGK93_RS05100	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGK93_RS05100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGK93_RS05105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGK93_RS05110	COG0509	glycine decarboxylation via glycine cleavage system
CGK93_RS05120	COG3591	Belongs to the peptidase S1B family
CGK93_RS05120	COG1864	DNA RNA non-specific endonuclease
CGK93_RS05150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CGK93_RS05170	COG0459	protein refolding
CGK93_RS05175	COG0328	RNA-DNA hybrid ribonuclease activity
CGK93_RS05185	COG2205	protein histidine kinase activity
CGK93_RS05190	COG0745	RESPONSE REGULATOR receiver
CGK93_RS05200	COG0583	DNA-binding transcription factor activity
CGK93_RS05210	COG2132	Multicopper oxidase
CGK93_RS05235	COG1278	Cold shock
CGK93_RS05245	COG2814	Major facilitator Superfamily
CGK93_RS05260	COG0739	heme binding
CGK93_RS05265	COG3103	Sh3 type 3 domain protein
CGK93_RS05265	COG1388	LysM domain
CGK93_RS05265	COG0791	NLP P60 protein
CGK93_RS05280	COG0746	molybdenum cofactor guanylyltransferase activity
CGK93_RS05295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CGK93_RS05315	COG1126	abc transporter atp-binding protein
CGK93_RS05325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_RS05340	COG0488	(ABC) transporter
CGK93_RS05345	COG1132	(ABC) transporter
CGK93_RS05375	COG0483	inositol monophosphate 1-phosphatase activity
CGK93_RS05400	COG0045	succinate-CoA ligase (ADP-forming) activity
CGK93_RS05415	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CGK93_RS05455	COG1396	sequence-specific DNA binding
CGK93_RS05470	COG0028	Belongs to the TPP enzyme family
CGK93_RS05500	COG3142	Participates in the control of copper homeostasis
CGK93_RS05535	COG1175	transmembrane transport
CGK93_RS05540	COG0395	ABC-type sugar transport system, permease component
CGK93_RS05545	COG1609	Transcriptional regulator
CGK93_RS05560	COG1609	Transcriptional regulator
CGK93_RS05570	COG0395	ABC-type sugar transport system, permease component
CGK93_RS05590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CGK93_RS05620	COG0739	heme binding
CGK93_RS05620	COG0741	lytic transglycosylase activity
CGK93_RS05620	COG1196	nuclear chromosome segregation
CGK93_RS05630	COG1401	restriction endodeoxyribonuclease activity
CGK93_RS05645	COG5002	protein histidine kinase activity
CGK93_RS05650	COG0745	RESPONSE REGULATOR receiver
CGK93_RS05670	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CGK93_RS05685	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS05720	COG1902	pentaerythritol trinitrate reductase activity
CGK93_RS05735	COG2376	Dihydroxyacetone kinase
CGK93_RS05740	COG0698	ribose 5-phosphate isomerase
CGK93_RS05745	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGK93_RS05750	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS05755	COG2271	Major facilitator Superfamily
CGK93_RS05760	COG0149	triose-phosphate isomerase activity
CGK93_RS05815	COG3103	Sh3 type 3 domain protein
CGK93_RS05815	COG0366	Alpha amylase catalytic
CGK93_RS05820	COG1254	Belongs to the acylphosphatase family
CGK93_RS05825	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
CGK93_RS05835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGK93_RS05840	COG2186	Transcriptional regulator
CGK93_RS05845	COG0477	Major facilitator Superfamily
CGK93_RS05855	COG0640	Transcriptional regulator
CGK93_RS05865	COG4209	transmembrane transport
CGK93_RS05870	COG0395	ABC-type sugar transport system, permease component
CGK93_RS05885	COG0402	S-adenosylhomocysteine deaminase activity
CGK93_RS05920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGK93_RS05925	COG1472	Belongs to the glycosyl hydrolase 3 family
CGK93_RS05930	COG0673	inositol 2-dehydrogenase activity
CGK93_RS05945	COG1609	Transcriptional regulator
CGK93_RS05965	COG2365	Tyrosine phosphatase family
CGK93_RS05970	COG3639	organic phosphonate transmembrane transporter activity
CGK93_RS05975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CGK93_RS05985	COG0477	Major facilitator Superfamily
CGK93_RS06000	COG0604	alcohol dehydrogenase
CGK93_RS06010	COG1309	transcriptional regulator
CGK93_RS06080	COG1846	Transcriptional regulator
CGK93_RS06085	COG0697	spore germination
CGK93_RS06125	COG0515	serine threonine protein kinase
CGK93_RS06125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CGK93_RS06140	COG1401	restriction endodeoxyribonuclease activity
CGK93_RS06185	COG0531	amino acid
CGK93_RS06205	COG2072	flavoprotein involved in K transport
CGK93_RS06215	COG1278	Cold shock
CGK93_RS06230	COG0477	Major facilitator Superfamily
CGK93_RS06235	COG0501	Belongs to the peptidase M48B family
CGK93_RS06250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGK93_RS06275	COG0789	Transcriptional regulator
CGK93_RS06285	COG0484	heat shock protein binding
CGK93_RS06315	COG2814	Major facilitator Superfamily
CGK93_RS06320	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CGK93_RS06330	COG0138	bifunctional purine biosynthesis protein purh
CGK93_RS06345	COG2838	Isocitrate dehydrogenase
CGK93_RS06355	COG3639	organic phosphonate transmembrane transporter activity
CGK93_RS06360	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CGK93_RS06375	COG2188	Transcriptional regulator
CGK93_RS06380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGK93_RS06410	COG1136	(ABC) transporter
CGK93_RS06410	COG0577	efflux transmembrane transporter activity
CGK93_RS06415	COG0577	efflux transmembrane transporter activity
CGK93_RS06415	COG1136	(ABC) transporter
CGK93_RS06420	COG1136	(ABC) transporter
CGK93_RS06425	COG0577	efflux transmembrane transporter activity
CGK93_RS06425	COG1136	(ABC) transporter
CGK93_RS06430	COG4213	ABC transporter substrate-binding protein
CGK93_RS06440	COG1129	ABC transporter
CGK93_RS06450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGK93_RS06460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGK93_RS06465	COG0531	amino acid
CGK93_RS06495	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGK93_RS06500	COG1131	(ABC) transporter
CGK93_RS06535	COG0180	Tryptophanyl-tRNA synthetase
CGK93_RS06570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CGK93_RS06585	COG2009	succinate dehydrogenase
CGK93_RS06595	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGK93_RS06595	COG1473	amidohydrolase
CGK93_RS06600	COG1846	Transcriptional regulator
CGK93_RS06605	COG1764	response to oxidative stress
CGK93_RS06610	COG2130	NADP-dependent
CGK93_RS06615	COG1744	ABC transporter substrate-binding protein PnrA-like
CGK93_RS06620	COG3845	ABC transporter
CGK93_RS06625	COG4603	Belongs to the binding-protein-dependent transport system permease family
CGK93_RS06630	COG1079	Belongs to the binding-protein-dependent transport system permease family
CGK93_RS06650	COG0586	Pfam SNARE associated Golgi protein
CGK93_RS06655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CGK93_RS06660	COG3956	TIGRFAM MazG family protein
CGK93_RS06665	COG0148	phosphopyruvate hydratase activity
CGK93_RS06690	COG1252	NADH dehydrogenase
CGK93_RS06730	COG0559	Belongs to the binding-protein-dependent transport system permease family
CGK93_RS06745	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CGK93_RS06755	COG2017	converts alpha-aldose to the beta-anomer
CGK93_RS06765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGK93_RS06775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CGK93_RS06785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGK93_RS06795	COG1331	Highly conserved protein containing a thioredoxin domain
CGK93_RS06805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGK93_RS06810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CGK93_RS06845	COG0114	fumarate hydratase activity
CGK93_RS06850	COG0288	reversible hydration of carbon dioxide
CGK93_RS06860	COG1494	fructose-1,6-bisphosphatase
CGK93_RS06870	COG1482	cell wall glycoprotein biosynthetic process
CGK93_RS06930	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CGK93_RS06935	COG1376	ErfK ybiS ycfS ynhG family protein
CGK93_RS06945	COG1357	PFAM Pentapeptide repeats (8 copies)
CGK93_RS07000	COG0714	Associated with various cellular activities
CGK93_RS07005	COG0084	hydrolase, TatD family'
CGK93_RS07010	COG3583	domain protein
CGK93_RS07015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CGK93_RS07020	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CGK93_RS07025	COG0488	(ABC) transporter
CGK93_RS07035	COG1309	transcriptional regulator
CGK93_RS07045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CGK93_RS07050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CGK93_RS07055	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CGK93_RS07060	COG0193	aminoacyl-tRNA hydrolase activity
CGK93_RS07105	COG0702	epimerase
CGK93_RS07115	COG1988	membrane-bound metal-dependent
CGK93_RS07125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CGK93_RS07175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGK93_RS07195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGK93_RS07200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGK93_RS07210	COG0492	ferredoxin-NADP+ reductase activity
CGK93_RS07215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGK93_RS07235	COG0456	acetyltransferase
CGK93_RS07245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGK93_RS07255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CGK93_RS07255	COG1648	precorrin-2 dehydrogenase activity
CGK93_RS07270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGK93_RS07275	COG1621	beta-fructofuranosidase activity
CGK93_RS07305	COG0243	molybdopterin cofactor binding
CGK93_RS07310	COG2223	nitrite transmembrane transporter activity
CGK93_RS07315	COG0477	Major facilitator Superfamily
CGK93_RS07320	COG4770	biotin carboxylase activity
CGK93_RS07325	COG0424	maF-like protein
CGK93_RS07330	COG2409	Drug exporters of the RND superfamily
CGK93_RS07335	COG1309	transcriptional regulator
CGK93_RS07340	COG0393	Putative heavy-metal-binding
CGK93_RS07345	COG1823	symporter activity
CGK93_RS07390	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS07395	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CGK93_RS07395	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CGK93_RS07420	COG0714	Associated with various cellular activities
CGK93_RS07440	COG0631	protein serine/threonine phosphatase activity
CGK93_RS07460	COG1674	ftsk spoiiie
CGK93_RS07470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CGK93_RS07475	COG0483	inositol monophosphate 1-phosphatase activity
CGK93_RS07485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_RS07495	COG0251	oxidation-reduction process
CGK93_RS07500	COG4565	transcriptional regulatory protein
CGK93_RS07510	COG2851	Citrate transporter
CGK93_RS07515	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGK93_RS07520	COG0154	amidase activity
CGK93_RS07525	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGK93_RS07535	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CGK93_RS07540	COG4209	transmembrane transport
CGK93_RS07545	COG0395	ABC-type sugar transport system, permease component
CGK93_RS07570	COG1063	alcohol dehydrogenase
CGK93_RS07575	COG0156	8-amino-7-oxononanoate synthase activity
CGK93_RS07590	COG1228	amidohydrolase
CGK93_RS07595	COG1470	cell adhesion involved in biofilm formation
CGK93_RS07595	COG0366	Alpha amylase catalytic
CGK93_RS07600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGK93_RS07605	COG1940	carbohydrate kinase activity
CGK93_RS07615	COG0191	fructose-bisphosphate aldolase activity
CGK93_RS07640	COG2873	o-acetylhomoserine
CGK93_RS07645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CGK93_RS07680	COG0423	glycine-tRNA ligase activity
CGK93_RS07705	COG0358	DNA primase activity
CGK93_RS07725	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CGK93_RS07730	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CGK93_RS07740	COG2814	Major facilitator Superfamily
CGK93_RS07750	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGK93_RS07780	COG0052	Belongs to the universal ribosomal protein uS2 family
CGK93_RS07785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CGK93_RS07790	COG0528	UMP kinase activity
CGK93_RS07795	COG0233	cytoplasmic translational termination
CGK93_RS07800	COG0575	Belongs to the CDS family
CGK93_RS07815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGK93_RS07825	COG3279	Response regulator of the LytR AlgR family
CGK93_RS07830	COG3275	phosphorelay sensor kinase activity
CGK93_RS07840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGK93_RS07845	COG1796	DNA polymerase
CGK93_RS07845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CGK93_RS07865	COG1522	sequence-specific DNA binding
CGK93_RS07875	COG0022	dehydrogenase e1 component
CGK93_RS07880	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_RS07885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGK93_RS07900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGK93_RS07910	COG1960	acyl-CoA dehydrogenase activity
CGK93_RS07935	COG0673	inositol 2-dehydrogenase activity
CGK93_RS07945	COG0673	inositol 2-dehydrogenase activity
CGK93_RS07955	COG1175	transmembrane transport
CGK93_RS07960	COG1653	transport
CGK93_RS07965	COG1609	Transcriptional regulator
CGK93_RS07975	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CGK93_RS07980	COG0750	zinc metalloprotease
CGK93_RS07990	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CGK93_RS08005	COG0442	prolyl-tRNA aminoacylation
CGK93_RS08015	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CGK93_RS08020	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
CGK93_RS08035	COG0779	Required for maturation of 30S ribosomal subunits
CGK93_RS08050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CGK93_RS08050	COG0481	GTPase activity
CGK93_RS08055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CGK93_RS08060	COG0590	tRNA wobble adenosine to inosine editing
CGK93_RS08070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CGK93_RS08090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CGK93_RS08095	COG1185	polyribonucleotide nucleotidyltransferase activity
CGK93_RS08100	COG0612	Peptidase, M16
CGK93_RS08120	COG0745	RESPONSE REGULATOR receiver
CGK93_RS08125	COG2205	protein histidine kinase activity
CGK93_RS08145	COG0521	Mo-molybdopterin cofactor biosynthetic process
CGK93_RS08155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CGK93_RS08180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGK93_RS08185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CGK93_RS08190	COG1674	ftsk spoiiie
CGK93_RS08200	COG1058	Belongs to the CinA family
CGK93_RS08200	COG1546	Belongs to the CinA family
CGK93_RS08205	COG1396	sequence-specific DNA binding
CGK93_RS08220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CGK93_RS08225	COG2137	regulation of response to DNA damage stimulus
CGK93_RS08230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CGK93_RS08235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CGK93_RS08240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CGK93_RS08245	COG2813	Specifically methylates the guanine in position
CGK93_RS08250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CGK93_RS08260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CGK93_RS08265	COG1388	LysM domain
CGK93_RS08270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGK93_RS08275	COG0131	Imidazoleglycerol-phosphate dehydratase
CGK93_RS08280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CGK93_RS08285	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CGK93_RS08305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CGK93_RS08310	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CGK93_RS08315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CGK93_RS08320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGK93_RS08325	COG2814	Major facilitator Superfamily
CGK93_RS08340	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CGK93_RS08360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CGK93_RS08365	COG0072	phenylalanine-tRNA ligase activity
CGK93_RS08365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGK93_RS08370	COG3591	Belongs to the peptidase S1B family
CGK93_RS08440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CGK93_RS08445	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CGK93_RS08450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CGK93_RS08455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CGK93_RS08460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CGK93_RS08465	COG1438	arginine binding
CGK93_RS08470	COG0137	argininosuccinate synthase activity
CGK93_RS08475	COG0165	Argininosuccinate lyase
CGK93_RS08490	COG2094	Belongs to the DNA glycosylase MPG family
CGK93_RS08500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CGK93_RS08525	COG0647	UMP catabolic process
CGK93_RS08540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CGK93_RS08545	COG0497	DNA recombination
CGK93_RS08550	COG0504	CTP synthase activity
CGK93_RS08570	COG0494	nUDIX hydrolase
CGK93_RS08580	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CGK93_RS08585	COG2079	MmgE PrpD family protein
CGK93_RS08610	COG3290	protein histidine kinase activity
CGK93_RS08615	COG1301	dicarboxylic acid transport
CGK93_RS08625	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CGK93_RS08630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CGK93_RS08645	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CGK93_RS08655	COG1160	GTP binding
CGK93_RS08665	COG1846	Transcriptional regulator
CGK93_RS08670	COG2814	Major facilitator Superfamily
CGK93_RS08680	COG0509	glycine decarboxylation via glycine cleavage system
CGK93_RS08685	COG1716	ATPase activity
CGK93_RS08710	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CGK93_RS08720	COG1940	carbohydrate kinase activity
CGK93_RS08745	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CGK93_RS08750	COG2815	serine threonine protein kinase
CGK93_RS08750	COG0515	serine threonine protein kinase
CGK93_RS08755	COG1388	LysM domain
CGK93_RS08755	COG3942	CHAP domain
CGK93_RS08765	COG0142	geranyltranstransferase activity
CGK93_RS08775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGK93_RS08785	COG2001	Belongs to the MraZ family
CGK93_RS08790	COG0275	rRNA processing
CGK93_RS08800	COG0768	penicillin binding
CGK93_RS08805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CGK93_RS08815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CGK93_RS08820	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CGK93_RS08830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGK93_RS08835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CGK93_RS08845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CGK93_RS08850	COG1496	oxidoreductase activity
CGK93_RS08855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CGK93_RS08860	COG1799	cell septum assembly
CGK93_RS08875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CGK93_RS08900	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CGK93_RS08905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CGK93_RS08910	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS08935	COG0174	glutamine synthetase
CGK93_RS08940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CGK93_RS08985	COG1045	serine acetyltransferase
CGK93_RS08990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CGK93_RS08995	COG0321	lipoyl(octanoyl) transferase activity
CGK93_RS09005	COG1090	epimerase
CGK93_RS09015	COG1764	response to oxidative stress
CGK93_RS09030	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_RS09035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGK93_RS09040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CGK93_RS09060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGK93_RS09090	COG1271	oxidase subunit
CGK93_RS09095	COG1294	oxidase, subunit
CGK93_RS09100	COG4988	ABC transporter
CGK93_RS09120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CGK93_RS09125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGK93_RS09125	COG1042	CoA-binding domain protein
CGK93_RS09125	COG0045	succinate-CoA ligase (ADP-forming) activity
CGK93_RS09140	COG1435	thymidine kinase activity
CGK93_RS09160	COG0756	dUTP diphosphatase activity
CGK93_RS09185	COG0569	domain protein
CGK93_RS09190	COG0531	amino acid
CGK93_RS09195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CGK93_RS09205	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CGK93_RS09230	COG1024	Enoyl-CoA hydratase
CGK93_RS09230	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGK93_RS09235	COG0183	Belongs to the thiolase family
CGK93_RS09265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGK93_RS09280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CGK93_RS09300	COG3135	benzoate transporter
CGK93_RS09310	COG0531	amino acid
CGK93_RS09400	COG3422	double-strand break repair
CGK93_RS09505	COG0210	DNA helicase
CGK93_RS09555	COG0242	peptide deformylase activity
CGK93_RS09560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CGK93_RS09570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CGK93_RS09590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGK93_RS09590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGK93_RS09600	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CGK93_RS09605	COG0140	phosphoribosyl-ATP diphosphatase activity
CGK93_RS09610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CGK93_RS09615	COG0107	imidazoleglycerol-phosphate synthase activity
CGK93_RS09625	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CGK93_RS09645	COG0134	indole-3-glycerol-phosphate synthase activity
CGK93_RS09650	COG0133	tryptophan synthase activity
CGK93_RS09655	COG0159	tryptophan synthase activity
CGK93_RS09660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CGK93_RS09870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CGK93_RS09885	COG0384	phenazine biosynthesis protein PhzF
CGK93_RS09900	COG2084	Dehydrogenase
CGK93_RS09905	COG1082	Xylose isomerase domain protein TIM barrel
CGK93_RS09910	COG0149	triose-phosphate isomerase activity
CGK93_RS09915	COG0698	ribose 5-phosphate isomerase
CGK93_RS09920	COG2376	Dihydroxyacetone kinase
CGK93_RS09925	COG2186	Transcriptional regulator
CGK93_RS09935	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS09970	COG1414	Transcriptional regulator
CGK93_RS09980	COG1917	Cupin 2, conserved barrel domain protein
CGK93_RS09985	COG0657	acetylesterase activity
CGK93_RS10010	COG2272	Belongs to the type-B carboxylesterase lipase family
CGK93_RS10015	COG3250	beta-galactosidase activity
CGK93_RS10020	COG2723	6-phospho-beta-galactosidase activity
CGK93_RS10025	COG2211	Major facilitator Superfamily
CGK93_RS10040	COG3958	Transketolase
CGK93_RS10045	COG3959	Transketolase, thiamine diphosphate binding domain
CGK93_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS10065	COG2814	Major facilitator Superfamily
CGK93_RS10075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGK93_RS10080	COG1414	Transcriptional regulator
CGK93_RS10095	COG3384	dioxygenase
CGK93_RS10105	COG0066	3-isopropylmalate dehydratase activity
CGK93_RS10115	COG2814	Major facilitator Superfamily
CGK93_RS10125	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS10150	COG3395	kinase activity
CGK93_RS10155	COG0235	Class ii aldolase
CGK93_RS10160	COG2508	Transcriptional regulator
CGK93_RS10210	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS10245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGK93_RS10255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGK93_RS10270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGK93_RS10275	COG0626	cystathionine gamma-synthase activity
CGK93_RS10295	COG0251	oxidation-reduction process
CGK93_RS10300	COG0531	amino acid
CGK93_RS10320	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_RS10325	COG0460	homoserine dehydrogenase
CGK93_RS10330	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CGK93_RS10340	COG0697	spore germination
CGK93_RS10350	COG0583	DNA-binding transcription factor activity
CGK93_RS10365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS10385	COG3250	beta-galactosidase activity
CGK93_RS10405	COG0444	Belongs to the ABC transporter superfamily
CGK93_RS10425	COG1609	Transcriptional regulator
CGK93_RS10430	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS10440	COG3250	beta-galactosidase activity
CGK93_RS10445	COG2814	Major facilitator Superfamily
CGK93_RS10455	COG3507	Belongs to the glycosyl hydrolase 43 family
CGK93_RS10465	COG2072	flavoprotein involved in K transport
CGK93_RS10480	COG4829	muconolactone delta-isomerase
CGK93_RS10490	COG3485	protocatechuate 3,4-dioxygenase
CGK93_RS10495	COG4638	Rieske (2fe-2S)
CGK93_RS10500	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CGK93_RS10520	COG0583	DNA-binding transcription factor activity
CGK93_RS10525	COG2814	Major facilitator Superfamily
CGK93_RS10550	COG3958	Transketolase
CGK93_RS10575	COG0154	amidase activity
CGK93_RS10595	COG1228	amidohydrolase
CGK93_RS10600	COG1228	amidohydrolase
CGK93_RS10610	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS10615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGK93_RS10640	COG0402	S-adenosylhomocysteine deaminase activity
CGK93_RS10650	COG3534	alpha-L-arabinofuranosidase
CGK93_RS10655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_RS10660	COG2186	Transcriptional regulator
CGK93_RS10665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CGK93_RS10680	COG1175	transmembrane transport
CGK93_RS10695	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS10710	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS10735	COG0477	Major facilitator Superfamily
CGK93_RS10740	COG1957	nucleoside hydrolase
CGK93_RS10750	COG1609	Transcriptional regulator
CGK93_RS10760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGK93_RS10770	COG1609	Transcriptional regulator
CGK93_RS10785	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS10790	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_RS10820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CGK93_RS10855	COG0395	ABC-type sugar transport system, permease component
CGK93_RS10860	COG1609	Transcriptional regulator
CGK93_RS10865	COG3534	alpha-L-arabinofuranosidase
CGK93_RS10955	COG1401	restriction endodeoxyribonuclease activity
CGK93_RS10975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGK93_RS10980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGK93_RS11000	COG0667	Aldo Keto reductase
CGK93_RS11030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGK93_RS11035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGK93_RS11045	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS11050	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS11065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGK93_RS11095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGK93_RS11105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGK93_RS11105	COG0446	pyridine nucleotide-disulphide oxidoreductase
CGK93_RS11200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CGK93_RS11205	COG0861	Integral membrane protein TerC family
CGK93_RS11285	COG0628	permease
CGK93_RS11325	COG0395	ABC-type sugar transport system, permease component
CGK93_RS11330	COG1063	alcohol dehydrogenase
CGK93_RS11370	COG0656	L-ascorbic acid biosynthetic process
CGK93_RS11395	COG1063	alcohol dehydrogenase
CGK93_RS11405	COG5002	protein histidine kinase activity
CGK93_RS11420	COG0673	inositol 2-dehydrogenase activity
CGK93_RS11430	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGK93_RS11435	COG1879	ABC-type sugar transport system periplasmic component
CGK93_RS11440	COG1082	Xylose isomerase domain protein TIM barrel
CGK93_RS11445	COG1082	Xylose isomerase domain protein TIM barrel
CGK93_RS11450	COG1129	ABC transporter
CGK93_RS11485	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CGK93_RS11490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CGK93_RS11495	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CGK93_RS11520	COG3842	ATPase activity
CGK93_RS11555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGK93_RS11565	COG0436	Aminotransferase
CGK93_RS11605	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_RS11615	COG0464	growth
CGK93_RS11620	COG2354	Protein conserved in bacteria
CGK93_RS11625	COG1609	Transcriptional regulator
CGK93_RS11630	COG0747	negative chemotaxis
CGK93_RS11635	COG0601	transmembrane transport
CGK93_RS11640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGK93_RS11645	COG0444	Belongs to the ABC transporter superfamily
CGK93_RS11650	COG4608	Belongs to the ABC transporter superfamily
CGK93_RS11670	COG2828	Protein conserved in bacteria
CGK93_RS11690	COG0747	negative chemotaxis
CGK93_RS11705	COG4172	Belongs to the ABC transporter superfamily
CGK93_RS11715	COG0531	amino acid
CGK93_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS11740	COG0475	glutathione-regulated potassium exporter activity
CGK93_RS11755	COG0028	Belongs to the TPP enzyme family
CGK93_RS11775	COG1120	ATPase activity
CGK93_RS11780	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CGK93_RS11800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGK93_RS11825	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_RS11845	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_RS11855	COG2814	Major facilitator Superfamily
CGK93_RS11860	COG0583	DNA-binding transcription factor activity
CGK93_RS11870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGK93_RS11885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGK93_RS11920	COG1643	Atp-dependent helicase
CGK93_RS11925	COG1228	amidohydrolase
CGK93_RS11965	COG0009	L-threonylcarbamoyladenylate synthase
CGK93_RS11975	COG1131	(ABC) transporter
CGK93_RS12025	COG3483	tryptophan 2,3-dioxygenase activity
CGK93_RS12060	COG2050	protein possibly involved in aromatic compounds catabolism
CGK93_RS12070	COG4552	Acetyltransferase involved in intracellular survival and related
CGK93_RS12080	COG0539	negative regulation of cytoplasmic translation
CGK93_RS12085	COG1739	Uncharacterized protein family UPF0029
CGK93_RS12090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CGK93_RS12090	COG0237	dephospho-CoA kinase activity
CGK93_RS12095	COG0556	nucleotide-excision repair
CGK93_RS12105	COG0477	Major facilitator Superfamily
CGK93_RS12120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CGK93_RS12130	COG4106	trans-aconitate 2-methyltransferase activity
CGK93_RS12145	COG0546	phosphoglycolate phosphatase activity
CGK93_RS12155	COG0322	excinuclease ABC activity
CGK93_RS12160	COG1660	Displays ATPase and GTPase activities
CGK93_RS12170	COG1481	regulation of sporulation
CGK93_RS12175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CGK93_RS12180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CGK93_RS12185	COG0126	phosphoglycerate kinase activity
CGK93_RS12190	COG0149	triose-phosphate isomerase activity
CGK93_RS12195	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CGK93_RS12205	COG0363	glucosamine-6-phosphate deaminase activity
CGK93_RS12220	COG0166	Belongs to the GPI family
CGK93_RS12225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGK93_RS12235	COG0109	protoheme IX farnesyltransferase activity
CGK93_RS12260	COG0577	efflux transmembrane transporter activity
CGK93_RS12260	COG1136	(ABC) transporter
CGK93_RS12265	COG1612	heme a metabolic process
CGK93_RS12270	COG0842	Transport permease protein
CGK93_RS12275	COG1131	(ABC) transporter
CGK93_RS12290	COG0719	Fe-S assembly protein
CGK93_RS12300	COG0396	ATPase activity
CGK93_RS12305	COG2151	metal-sulfur cluster biosynthetic enzyme
CGK93_RS12315	COG0318	PFAM AMP-dependent synthetase and ligase
CGK93_RS12330	COG1122	ATPase activity
CGK93_RS12335	COG1268	BioY protein
CGK93_RS12340	COG0488	(ABC) transporter
CGK93_RS12365	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS12370	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS12375	COG1129	ABC transporter
CGK93_RS12385	COG0560	Phosphoserine phosphatase
CGK93_RS12385	COG3830	Belongs to the UPF0237 family
CGK93_RS12390	COG1119	ATPase activity
CGK93_RS12405	COG0254	rRNA binding
CGK93_RS12420	COG2855	membrane
CGK93_RS12445	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CGK93_RS12450	COG0297	glycogen (starch) synthase activity
CGK93_RS12465	COG0183	Belongs to the thiolase family
CGK93_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS12485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGK93_RS12505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CGK93_RS12520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CGK93_RS12530	COG1215	transferase activity, transferring glycosyl groups
CGK93_RS12575	COG1088	dTDP-glucose 4,6-dehydratase activity
CGK93_RS12580	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CGK93_RS12585	COG0667	Aldo Keto reductase
CGK93_RS12590	COG1968	undecaprenyl-diphosphatase activity
CGK93_RS12595	COG0215	cysteine-tRNA ligase activity
CGK93_RS12605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGK93_RS12610	COG0517	IMP dehydrogenase activity
CGK93_RS12610	COG1994	Peptidase M50
CGK93_RS12620	COG1222	aaa ATPase
CGK93_RS12625	COG4122	O-methyltransferase activity
CGK93_RS12635	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CGK93_RS12640	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CGK93_RS12645	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CGK93_RS12650	COG0545	Peptidyl-prolyl cis-trans isomerase
CGK93_RS12670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGK93_RS12675	COG0805	protein transport
CGK93_RS12680	COG4581	dead DEAH box helicase
CGK93_RS12685	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CGK93_RS12690	COG1216	Glycosyl transferase, family 2
CGK93_RS12715	COG4946	Tricorn protease homolog
CGK93_RS12715	COG0823	Involved in the tonB-independent uptake of proteins
CGK93_RS12715	COG1506	peptidase
CGK93_RS12720	COG0242	peptide deformylase activity
CGK93_RS12740	COG3424	synthase
CGK93_RS12745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CGK93_RS12760	COG2188	Transcriptional regulator
CGK93_RS12765	COG3718	enzyme involved in inositol metabolism
CGK93_RS12770	COG0673	inositol 2-dehydrogenase activity
CGK93_RS12775	COG0673	inositol 2-dehydrogenase activity
CGK93_RS12780	COG0673	inositol 2-dehydrogenase activity
CGK93_RS12790	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGK93_RS12820	COG2814	Major facilitator Superfamily
CGK93_RS12825	COG1082	Xylose isomerase domain protein TIM barrel
CGK93_RS12830	COG0673	inositol 2-dehydrogenase activity
CGK93_RS12845	COG3962	Belongs to the TPP enzyme family
CGK93_RS12855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGK93_RS12860	COG1942	4-Oxalocrotonate Tautomerase
CGK93_RS12890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CGK93_RS12895	COG1845	cytochrome c oxidase, subunit III
CGK93_RS12900	COG2010	Cytochrome c
CGK93_RS12905	COG0723	plastoquinol--plastocyanin reductase activity
CGK93_RS12910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CGK93_RS12915	COG2188	Transcriptional regulator
CGK93_RS12920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGK93_RS12930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGK93_RS12935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CGK93_RS12955	COG0167	dihydroorotate dehydrogenase activity
CGK93_RS12970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGK93_RS12975	COG1381	Involved in DNA repair and RecF pathway recombination
CGK93_RS12980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CGK93_RS12985	COG3590	peptidase
CGK93_RS12990	COG1316	TRANSCRIPTIONal
CGK93_RS12995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CGK93_RS13005	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CGK93_RS13020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CGK93_RS13025	COG0484	heat shock protein binding
CGK93_RS13030	COG1420	regulation of RNA biosynthetic process
CGK93_RS13050	COG0481	GTPase activity
CGK93_RS13060	COG0268	Binds directly to 16S ribosomal RNA
CGK93_RS13080	COG1307	EDD domain protein, DegV family
CGK93_RS13085	COG0495	leucyl-tRNA aminoacylation
CGK93_RS13090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CGK93_RS13095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CGK93_RS13100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGK93_RS13105	COG2390	Transcriptional regulator
CGK93_RS13110	COG0656	L-ascorbic acid biosynthetic process
CGK93_RS13120	COG0438	transferase activity, transferring glycosyl groups
CGK93_RS13130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CGK93_RS13140	COG1758	RNA polymerase activity
CGK93_RS13145	COG0194	GDP metabolic process
CGK93_RS13155	COG0284	orotidine-5'-phosphate decarboxylase activity
CGK93_RS13160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CGK93_RS13165	COG0505	Belongs to the CarA family
CGK93_RS13175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CGK93_RS13180	COG0540	Belongs to the ATCase OTCase family
CGK93_RS13185	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CGK93_RS13195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CGK93_RS13200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CGK93_RS13210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CGK93_RS13215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CGK93_RS13220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CGK93_RS13225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGK93_RS13235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CGK93_RS13240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CGK93_RS13255	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CGK93_RS13275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CGK93_RS13280	COG0124	histidyl-tRNA synthetase
CGK93_RS13290	COG1196	nuclear chromosome segregation
CGK93_RS13300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGK93_RS13305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGK93_RS13310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGK93_RS13320	COG2255	four-way junction helicase activity
CGK93_RS13325	COG0632	four-way junction helicase activity
CGK93_RS13330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CGK93_RS13335	COG0217	transcriptional regulatory protein
CGK93_RS13340	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CGK93_RS13360	COG0339	signal peptide processing
CGK93_RS13365	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CGK93_RS13370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGK93_RS13380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CGK93_RS13385	COG0587	DNA-directed DNA polymerase activity
CGK93_RS13410	COG2135	peptidase activity
CGK93_RS13425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGK93_RS13460	COG4804	nuclease activity
CGK93_RS13480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGK93_RS13485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGK93_RS13490	COG1780	Probably involved in ribonucleotide reductase function
CGK93_RS13500	COG0583	DNA-binding transcription factor activity
CGK93_RS13535	COG0714	Associated with various cellular activities
CGK93_RS13555	COG1653	transport
CGK93_RS13565	COG2813	Specifically methylates the guanine in position
CGK93_RS13590	COG0799	negative regulation of ribosome biogenesis
CGK93_RS13600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CGK93_RS13610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CGK93_RS13615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CGK93_RS13620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CGK93_RS13625	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CGK93_RS13630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CGK93_RS13635	COG0351	phosphomethylpyrimidine kinase
CGK93_RS13635	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CGK93_RS13635	COG0352	thiamine-phosphate diphosphorylase activity
CGK93_RS13640	COG1530	ribonuclease E activity
CGK93_RS13650	COG0105	UTP biosynthetic process
CGK93_RS13660	COG0285	dihydrofolate synthase activity
CGK93_RS13665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CGK93_RS13680	COG0525	valine-tRNA ligase activity
CGK93_RS13685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGK93_RS13690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CGK93_RS13695	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CGK93_RS13700	COG0740	serine-type endopeptidase activity
CGK93_RS13705	COG0740	serine-type endopeptidase activity
CGK93_RS13710	COG0544	peptidyl-prolyl cis-trans isomerase activity
CGK93_RS13755	COG0668	transmembrane transport
CGK93_RS13770	COG1946	Acyl-CoA thioesterase
CGK93_RS13795	COG0629	single-stranded DNA binding
CGK93_RS13830	COG0242	peptide deformylase activity
CGK93_RS13860	COG3022	response to hydroperoxide
CGK93_RS13875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGK93_RS13885	COG1045	serine acetyltransferase
CGK93_RS13890	COG0300	oxidoreductase activity
CGK93_RS13895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CGK93_RS13905	COG1063	alcohol dehydrogenase
CGK93_RS13910	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS13920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_RS13930	COG0477	Major facilitator Superfamily
CGK93_RS14055	COG0305	Participates in initiation and elongation during chromosome replication
CGK93_RS14060	COG0305	Participates in initiation and elongation during chromosome replication
CGK93_RS14310	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CGK93_RS14325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGK93_RS14330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGK93_RS14345	COG4974	Belongs to the 'phage' integrase family
CGK93_RS14360	COG0792	nuclease activity
CGK93_RS14370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGK93_RS14380	COG0681	Belongs to the peptidase S26 family
CGK93_RS14385	COG0335	large ribosomal subunit rRNA binding
CGK93_RS14390	COG0336	Belongs to the RNA methyltransferase TrmD family
CGK93_RS14395	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CGK93_RS14400	COG1837	Belongs to the UPF0109 family
CGK93_RS14405	COG0228	four-way junction DNA binding
CGK93_RS14415	COG2514	catechol 2,3-dioxygenase activity
CGK93_RS14425	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CGK93_RS14440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CGK93_RS14455	COG2814	Major facilitator Superfamily
CGK93_RS14490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGK93_RS14495	COG0571	ribonuclease III activity
CGK93_RS14500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CGK93_RS14510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CGK93_RS14525	COG0742	ribosomal rna small subunit methyltransferase
CGK93_RS14550	COG1181	Belongs to the D-alanine--D-alanine ligase family
CGK93_RS14555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CGK93_RS14565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGK93_RS14570	COG0066	3-isopropylmalate dehydratase activity
CGK93_RS14575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CGK93_RS14580	COG1414	Transcriptional regulator
CGK93_RS14620	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_RS14625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGK93_RS14630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGK93_RS14635	COG0473	3-isopropylmalate dehydrogenase activity
CGK93_RS14640	COG4585	Histidine kinase
CGK93_RS14645	COG2197	response regulator
CGK93_RS14650	COG0577	efflux transmembrane transporter activity
CGK93_RS14650	COG1136	(ABC) transporter
CGK93_RS14665	COG0577	efflux transmembrane transporter activity
CGK93_RS14665	COG1136	(ABC) transporter
CGK93_RS14675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_RS14680	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CGK93_RS14685	COG0440	acetolactate synthase activity
CGK93_RS14695	COG0129	dihydroxy-acid dehydratase activity
CGK93_RS14705	COG0088	Forms part of the polypeptide exit tunnel
CGK93_RS14710	COG2133	pyrroloquinoline quinone binding
CGK93_RS14745	COG0579	oxidoreductase
CGK93_RS14750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CGK93_RS14755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_RS14765	COG1305	Transglutaminase-like
CGK93_RS14790	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_RS14800	COG1104	cysteine desulfurase activity
CGK93_RS14815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CGK93_RS14825	COG1522	sequence-specific DNA binding
CGK93_RS14830	COG1113	amino acid transport
CGK93_RS14840	COG0022	dehydrogenase e1 component
CGK93_RS14845	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_RS14865	COG0477	Major facilitator Superfamily
CGK93_RS14870	COG1414	Transcriptional regulator
CGK93_RS14880	COG0531	amino acid
CGK93_RS14895	COG0419	ATPase involved in DNA repair
CGK93_RS14900	COG0420	3'-5' exonuclease activity
CGK93_RS14915	COG2149	membrane
CGK93_RS14940	COG1131	(ABC) transporter
CGK93_RS14955	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CGK93_RS14960	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CGK93_RS14965	COG1234	tRNA 3'-trailer cleavage
CGK93_RS14970	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CGK93_RS14980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CGK93_RS14990	COG1335	isochorismatase
CGK93_RS15005	COG0363	glucosamine-6-phosphate deaminase activity
CGK93_RS15020	COG1902	pentaerythritol trinitrate reductase activity
CGK93_RS15050	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CGK93_RS15055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CGK93_RS15065	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CGK93_RS15070	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CGK93_RS15080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CGK93_RS15085	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CGK93_RS15090	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CGK93_RS15095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CGK93_RS15100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGK93_RS15105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CGK93_RS15110	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGK93_RS15115	COG0356	it plays a direct role in the translocation of protons across the membrane
CGK93_RS15135	COG1216	Glycosyl transferase, family 2
CGK93_RS15150	COG2890	protein-(glutamine-N5) methyltransferase activity
CGK93_RS15155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CGK93_RS15165	COG0083	homoserine kinase activity
CGK93_RS15170	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CGK93_RS15175	COG0460	homoserine dehydrogenase
CGK93_RS15180	COG0019	diaminopimelate decarboxylase activity
CGK93_RS15185	COG0018	arginyl-trna synthetase
CGK93_RS15200	COG0543	2 iron, 2 sulfur cluster binding
CGK93_RS15200	COG0633	Ferredoxin
CGK93_RS15230	COG1643	Atp-dependent helicase
CGK93_RS15235	COG0537	adenosine 5'-monophosphoramidase activity
CGK93_RS15240	COG1064	alcohol dehydrogenase
CGK93_RS15265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CGK93_RS15270	COG1121	(ABC) transporter
CGK93_RS15275	COG0803	Belongs to the bacterial solute-binding protein 9 family
CGK93_RS15285	COG1253	flavin adenine dinucleotide binding
CGK93_RS15290	COG0567	Dehydrogenase, E1 component
CGK93_RS15290	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_RS15320	COG1595	DNA-templated transcription, initiation
CGK93_RS15330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CGK93_RS15340	COG0483	inositol monophosphate 1-phosphatase activity
CGK93_RS15345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CGK93_RS15370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGK93_RS15380	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CGK93_RS15390	COG2177	Part of the ABC transporter FtsEX involved in
CGK93_RS15395	COG2884	Cell division ATP-binding protein ftsE
CGK93_RS15400	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CGK93_RS15510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CGK93_RS15540	COG2902	Dehydrogenase
CGK93_RS15575	COG0653	protein targeting
CGK93_RS15580	COG3214	Protein conserved in bacteria
CGK93_RS15585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CGK93_RS15595	COG5401	PFAM Sporulation and spore germination
CGK93_RS15600	COG5002	protein histidine kinase activity
CGK93_RS15625	COG0714	Associated with various cellular activities
CGK93_RS15660	COG0601	transmembrane transport
CGK93_RS15680	COG0482	sulfurtransferase activity
CGK93_RS15695	COG1597	lipid kinase activity
CGK93_RS15700	COG0484	heat shock protein binding
CGK93_RS15705	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CGK93_RS15725	COG3265	gluconokinase activity
CGK93_RS15730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGK93_RS15735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CGK93_RS15740	COG2086	electron transfer activity
CGK93_RS15755	COG1842	Phage shock protein A
CGK93_RS15760	COG2188	Transcriptional regulator
CGK93_RS15775	COG1615	UPF0182 protein
CGK93_RS15780	COG3480	Lon protease (S16) C-terminal proteolytic domain
CGK93_RS15800	COG2816	NAD+ diphosphatase activity
CGK93_RS15830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_RS15835	COG0765	amino acid transport
CGK93_RS15840	COG1126	abc transporter atp-binding protein
CGK93_RS15845	COG1472	Belongs to the glycosyl hydrolase 3 family
CGK93_RS15850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CGK93_RS15860	COG0113	porphobilinogen synthase activity
CGK93_RS15870	COG0181	hydroxymethylbilane synthase activity
CGK93_RS15875	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CGK93_RS15880	COG3253	May function as heme-dependent peroxidase
CGK93_RS15890	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CGK93_RS15895	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CGK93_RS15905	COG1309	transcriptional regulator
CGK93_RS15920	COG2154	pterin-4-alpha-carbinolamine dehydratase
CGK93_RS15925	COG2022	thiamine diphosphate biosynthetic process
CGK93_RS15935	COG2022	thiamine diphosphate biosynthetic process
CGK93_RS15935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGK93_RS15940	COG0352	thiamine-phosphate diphosphorylase activity
CGK93_RS15950	COG2314	TM2 domain
CGK93_RS15960	COG0513	Belongs to the DEAD box helicase family
CGK93_RS15970	COG2095	MarC family integral membrane protein
CGK93_RS15990	COG2239	Acts as a magnesium transporter
CGK93_RS16005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGK93_RS16015	COG1595	DNA-templated transcription, initiation
CGK93_RS16020	COG4122	O-methyltransferase activity
CGK93_RS16045	COG1126	abc transporter atp-binding protein
CGK93_RS16050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_RS16055	COG0765	amino acid transport
CGK93_RS16060	COG0765	amino acid transport
CGK93_RS16065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGK93_RS16070	COG2171	N-acyltransferase activity
CGK93_RS16085	COG3226	Transcriptional regulator
CGK93_RS16090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CGK93_RS16120	COG1217	gtp-binding protein TYPA
CGK93_RS16135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGK93_RS16140	COG0601	transmembrane transport
CGK93_RS16145	COG0747	negative chemotaxis
CGK93_RS16150	COG0012	GTP binding
CGK93_RS16155	COG1322	Protein conserved in bacteria
CGK93_RS16160	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CGK93_RS16170	COG1570	exodeoxyribonuclease VII activity
CGK93_RS16175	COG1722	exodeoxyribonuclease VII activity
CGK93_RS16180	COG2326	polyphosphate kinase activity
CGK93_RS16210	COG1162	GTPase activity
CGK93_RS16230	COG2971	BadF BadG BcrA BcrD
CGK93_RS16235	COG2070	2-Nitropropane dioxygenase
CGK93_RS16240	COG0583	DNA-binding transcription factor activity
CGK93_RS16245	COG2814	Major facilitator Superfamily
CGK93_RS16250	COG3548	integral membrane protein
CGK93_RS16275	COG0598	Magnesium transport protein CorA
CGK93_RS16285	COG1528	Iron-storage protein
CGK93_RS16290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGK93_RS16295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGK93_RS16305	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CGK93_RS16335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CGK93_RS16340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CGK93_RS16360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CGK93_RS16360	COG0519	Catalyzes the synthesis of GMP from XMP
CGK93_RS16380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGK93_RS16420	COG2072	flavoprotein involved in K transport
CGK93_RS16435	COG0459	protein refolding
CGK93_RS16440	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CGK93_RS16455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGK93_RS16460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CGK93_RS16470	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGK93_RS16475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CGK93_RS16480	COG0456	acetyltransferase
CGK93_RS16490	COG0802	atpase or kinase
CGK93_RS16495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGK93_RS16505	COG1486	melibiose metabolic process
CGK93_RS16515	COG0438	transferase activity, transferring glycosyl groups
CGK93_RS16520	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CGK93_RS16530	COG0667	Aldo Keto reductase
CGK93_RS16555	COG0736	holo-[acyl-carrier-protein] synthase activity
CGK93_RS16560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGK93_RS16575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGK93_RS16580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CGK93_RS16585	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CGK93_RS16615	COG0455	bacterial-type flagellum organization
CGK93_RS16635	COG0101	tRNA pseudouridine synthase activity
CGK93_RS16640	COG0203	ribosomal protein L17
CGK93_RS16645	COG0202	RNA polymerase activity
CGK93_RS16650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CGK93_RS16655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CGK93_RS16660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CGK93_RS16665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CGK93_RS16700	COG0318	PFAM AMP-dependent synthetase and ligase
CGK93_RS16705	COG2124	cytochrome p450
CGK93_RS16710	COG1215	transferase activity, transferring glycosyl groups
CGK93_RS16715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGK93_RS16720	COG0563	adenylate kinase activity
CGK93_RS16730	COG0200	Binds to the 23S rRNA
CGK93_RS16735	COG1841	ribosomal large subunit assembly
CGK93_RS16740	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CGK93_RS16750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CGK93_RS16755	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CGK93_RS16760	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CGK93_RS16765	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CGK93_RS16770	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CGK93_RS16775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CGK93_RS16780	COG0255	Belongs to the universal ribosomal protein uL29 family
CGK93_RS16785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CGK93_RS16790	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CGK93_RS16795	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CGK93_RS16800	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CGK93_RS16805	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CGK93_RS16810	COG0089	rRNA binding
CGK93_RS16815	COG0088	Forms part of the polypeptide exit tunnel
CGK93_RS16820	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CGK93_RS16825	COG0051	transcription antitermination factor activity, RNA binding
CGK93_RS16840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CGK93_RS16845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CGK93_RS16850	COG0049	tRNA binding
CGK93_RS16855	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CGK93_RS16860	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGK93_RS16865	COG0085	RNA polymerase activity
CGK93_RS16870	COG0183	Belongs to the thiolase family
CGK93_RS16875	COG0442	prolyl-tRNA aminoacylation
CGK93_RS16880	COG0222	ribosome binding
CGK93_RS16885	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CGK93_RS16900	COG0081	regulation of translation
CGK93_RS16905	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CGK93_RS16915	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CGK93_RS16925	COG0436	Aminotransferase
CGK93_RS16930	COG2197	response regulator
CGK93_RS16980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGK93_RS16990	COG3485	protocatechuate 3,4-dioxygenase
CGK93_RS17000	COG0745	RESPONSE REGULATOR receiver
CGK93_RS17005	COG0456	acetyltransferase
CGK93_RS17010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CGK93_RS17030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CGK93_RS17035	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGK93_RS17045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CGK93_RS17075	COG2030	dehydratase
CGK93_RS17105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CGK93_RS17115	COG4989	oxidoreductase activity
CGK93_RS17120	COG0366	Alpha amylase catalytic
CGK93_RS17130	COG1175	transmembrane transport
CGK93_RS17140	COG1940	carbohydrate kinase activity
CGK93_RS17165	COG1376	ErfK ybiS ycfS ynhG family protein
CGK93_RS17195	COG0754	glutathionylspermidine amidase activity
CGK93_RS17205	COG5650	phosphatidylinositol metabolic process
CGK93_RS17220	COG1653	transport
CGK93_RS17260	COG5650	phosphatidylinositol metabolic process
CGK93_RS17295	COG0318	PFAM AMP-dependent synthetase and ligase
CGK93_RS17305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGK93_RS17310	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CGK93_RS17310	COG5479	isomerase activity
CGK93_RS17315	COG1309	transcriptional regulator
CGK93_RS17320	COG1131	(ABC) transporter
CGK93_RS17340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CGK93_RS17355	COG1666	GTP binding
CGK93_RS17360	COG0501	Belongs to the peptidase M48B family
CGK93_RS17390	COG0531	amino acid
CGK93_RS17435	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_RS17440	COG2508	Transcriptional regulator
CGK93_RS17445	COG2807	transmembrane transport
CGK93_RS17450	COG2186	Transcriptional regulator
CGK93_RS17455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGK93_RS17455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGK93_RS17475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CGK93_RS17475	COG1648	precorrin-2 dehydrogenase activity
CGK93_RS17485	COG2066	Belongs to the glutaminase family
CGK93_RS17505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_RS17540	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGK93_RS17555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CGK93_RS17560	COG1116	anion transmembrane transporter activity
CGK93_RS17570	COG2040	homocysteine
CGK93_RS17590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGK93_RS17600	COG2860	membrane
CGK93_RS17615	COG0142	geranyltranstransferase activity
CGK93_RS17625	COG2226	methyltransferase
CGK93_RS17630	COG1169	isochorismate synthase
CGK93_RS17635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_RS17640	COG0765	amino acid transport
CGK93_RS17655	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CGK93_RS17665	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_RS17685	COG1621	beta-fructofuranosidase activity
CGK93_RS17690	COG0395	ABC-type sugar transport system, permease component
CGK93_RS17695	COG1175	transmembrane transport
CGK93_RS17750	COG1404	Belongs to the peptidase S8 family
CGK93_RS17760	COG0662	Cupin 2, conserved barrel domain protein
CGK93_RS17780	COG1733	regulation of RNA biosynthetic process
CGK93_RS17795	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_RS17800	COG0022	dehydrogenase e1 component
CGK93_RS17825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CGK93_RS17850	COG1215	transferase activity, transferring glycosyl groups
CGK93_RS17860	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CGK93_RS17870	COG1134	teichoic acid transport
CGK93_RS17880	COG0438	transferase activity, transferring glycosyl groups
CGK93_RS17900	COG1316	TRANSCRIPTIONal
CGK93_RS17925	COG0596	Alpha beta hydrolase
CGK93_RS17935	COG4585	Histidine kinase
CGK93_RS17965	COG3655	Transcriptional regulator
CGK93_RS17995	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CGK93_RS18005	COG1597	lipid kinase activity
CGK93_RS18010	COG1024	Enoyl-CoA hydratase
CGK93_RS18015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGK93_RS18020	COG2151	metal-sulfur cluster biosynthetic enzyme
CGK93_RS18025	COG3396	Phenylacetate-CoA oxygenase
CGK93_RS18030	COG3460	Phenylacetate-CoA oxygenase
CGK93_RS18035	COG3396	Phenylacetate-CoA oxygenase
CGK93_RS18045	COG1316	TRANSCRIPTIONal
CGK93_RS18050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CGK93_RS18105	COG0489	protein tyrosine kinase activity
CGK93_RS18110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGK93_RS18120	COG5002	protein histidine kinase activity
CGK93_RS18120	COG0784	Response regulator, receiver
CGK93_RS18120	COG2205	protein histidine kinase activity
CGK93_RS18125	COG3706	GGDEF domain
CGK93_RS18165	COG0438	transferase activity, transferring glycosyl groups
CGK93_RS18180	COG2226	methyltransferase
CGK93_RS18190	COG5002	protein histidine kinase activity
CGK93_RS18210	COG2050	protein possibly involved in aromatic compounds catabolism
CGK93_RS18215	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CGK93_RS18225	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_RS18225	COG2030	dehydratase
CGK93_RS18230	COG1216	Glycosyl transferase, family 2
CGK93_RS18240	COG2755	lipolytic protein G-D-S-L family
CGK93_RS18250	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGK93_RS18255	COG1024	Enoyl-CoA hydratase
CGK93_RS18260	COG0183	Belongs to the thiolase family
CGK93_RS18280	COG1022	Amp-dependent synthetase and ligase
CGK93_RS18305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGK93_RS18315	COG0488	(ABC) transporter
CGK93_RS18330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CGK93_RS18335	COG1121	(ABC) transporter
CGK93_RS18340	COG0803	Belongs to the bacterial solute-binding protein 9 family
CGK93_RS18345	COG1266	CAAX protease self-immunity
CGK93_RS18355	COG0395	ABC-type sugar transport system, permease component
CGK93_RS18360	COG1175	transmembrane transport
CGK93_RS18375	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CGK93_RS18425	COG0443	Heat shock 70 kDa protein
CGK93_RS18430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CGK93_RS18435	COG1333	cytochrome c biogenesis protein
CGK93_RS18440	COG0785	Cytochrome C biogenesis protein
CGK93_RS18450	COG0406	alpha-ribazole phosphatase activity
CGK93_RS18475	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CGK93_RS18505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CGK93_RS18510	COG3458	cephalosporin-C deacetylase activity
CGK93_RS18520	COG2755	lipolytic protein G-D-S-L family
CGK93_RS18525	COG0395	ABC-type sugar transport system, permease component
CGK93_RS18530	COG4209	transmembrane transport
CGK93_RS18535	COG1653	transport
CGK93_RS18540	COG5578	integral membrane protein
CGK93_RS18560	COG2814	Major facilitator Superfamily
CGK93_RS18570	COG0395	ABC-type sugar transport system, permease component
CGK93_RS18575	COG1175	transmembrane transport
CGK93_RS18595	COG0395	ABC-type sugar transport system, permease component
CGK93_RS18600	COG1175	transmembrane transport
CGK93_RS18625	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_RS18630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGK93_RS18640	COG0673	inositol 2-dehydrogenase activity
CGK93_RS18650	COG1802	Transcriptional regulator
CGK93_RS18660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CGK93_RS18665	COG0640	Transcriptional regulator
CGK93_RS18670	COG0123	including yeast histone deacetylase and acetoin utilization protein
CGK93_RS18675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CGK93_RS18680	COG0569	domain protein
CGK93_RS18685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGK93_RS18690	COG1082	Xylose isomerase domain protein TIM barrel
CGK93_RS18695	COG0248	Ppx GppA phosphatase
CGK93_RS18705	COG1754	DNA topoisomerase type I activity
CGK93_RS18705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGK93_RS18730	COG1054	Belongs to the UPF0176 family
CGK93_RS18740	COG1205	dead DEAH box helicase
CGK93_RS18740	COG1111	helicase
CGK93_RS18845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CGK93_RS18850	COG1349	DNA-binding transcription factor activity
CGK93_RS18865	COG1609	Transcriptional regulator
CGK93_RS18875	COG1175	transmembrane transport
CGK93_RS18880	COG0395	ABC-type sugar transport system, permease component
CGK93_RS18895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CGK93_RS18925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGK93_RS18930	COG1408	metallophosphoesterase
CGK93_RS18935	COG1132	(ABC) transporter
CGK93_RS18940	COG1132	(ABC) transporter
CGK93_RS18960	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CGK93_RS18965	COG0151	Belongs to the GarS family
CGK93_RS18980	COG1301	dicarboxylic acid transport
CGK93_RS18990	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS19000	COG1953	Uracil, thiamine, allantoin
CGK93_RS19005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CGK93_RS19025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CGK93_RS19035	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CGK93_RS19035	COG3608	succinylglutamate desuccinylase aspartoacylase
CGK93_RS19040	COG2252	PERMEase
CGK93_RS19045	COG0590	tRNA wobble adenosine to inosine editing
CGK93_RS19080	COG2233	PERMEase
CGK93_RS19090	COG1414	Transcriptional regulator
CGK93_RS19100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CGK93_RS19110	COG3257	ureidoglycine aminohydrolase activity
CGK93_RS19130	COG2318	DinB family
CGK93_RS19140	COG4499	WXG100 protein secretion system (Wss), protein YukC
CGK93_RS19140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGK93_RS19145	COG1053	succinate dehydrogenase
CGK93_RS19155	COG0446	pyridine nucleotide-disulphide oxidoreductase
CGK93_RS19155	COG1902	pentaerythritol trinitrate reductase activity
CGK93_RS19160	COG0673	inositol 2-dehydrogenase activity
CGK93_RS19165	COG0477	Major facilitator Superfamily
CGK93_RS19170	COG1414	Transcriptional regulator
CGK93_RS19175	COG0583	DNA-binding transcription factor activity
CGK93_RS19185	COG1063	alcohol dehydrogenase
CGK93_RS19190	COG1053	succinate dehydrogenase
CGK93_RS19220	COG0659	secondary active sulfate transmembrane transporter activity
CGK93_RS19250	COG0563	adenylate kinase activity
CGK93_RS19275	COG0477	Major facilitator Superfamily
CGK93_RS19285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CGK93_RS19295	COG3401	FG-GAP repeat protein
CGK93_RS19360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CGK93_RS19365	COG1733	regulation of RNA biosynthetic process
CGK93_RS19370	COG2267	carboxylic ester hydrolase activity
CGK93_RS19410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CGK93_RS19415	COG1024	Enoyl-CoA hydratase
CGK93_RS19420	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CGK93_RS19475	COG1942	4-Oxalocrotonate Tautomerase
CGK93_RS19540	COG0405	Gamma-glutamyltransferase
CGK93_RS19585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CGK93_RS19635	COG0673	inositol 2-dehydrogenase activity
CGK93_RS19650	COG1653	transport
CGK93_RS19655	COG1609	Transcriptional regulator
CGK93_RS19690	COG3093	addiction module antidote protein HigA
CGK93_RS19715	COG3622	Belongs to the hyi family
CGK93_RS19720	COG2084	Dehydrogenase
CGK93_RS19725	COG3960	tartronate-semialdehyde synthase activity
CGK93_RS19730	COG1929	Belongs to the glycerate kinase type-1 family
CGK93_RS19735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CGK93_RS19740	COG0745	RESPONSE REGULATOR receiver
CGK93_RS19750	COG0745	RESPONSE REGULATOR receiver
CGK93_RS19760	COG1366	Belongs to the anti-sigma-factor antagonist family
CGK93_RS19785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CGK93_RS19790	COG2814	Major facilitator Superfamily
CGK93_RS19800	COG0671	phosphoesterase, PA-phosphatase related
CGK93_RS19825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CGK93_RS19850	COG0542	response to heat
CGK93_RS19895	COG3304	Inner membrane component domain
CGK93_RS19905	COG0135	phosphoribosylanthranilate isomerase activity
CGK93_RS19925	COG0667	Aldo Keto reductase
CGK93_RS19965	COG1473	amidohydrolase
CGK93_RS19970	COG0477	Major facilitator Superfamily
CGK93_RS19975	COG2807	transmembrane transport
CGK93_RS19980	COG0259	pyridoxamine-phosphate oxidase activity
CGK93_RS19985	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CGK93_RS20025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGK93_RS20035	COG2188	Transcriptional regulator
CGK93_RS20055	COG1609	Transcriptional regulator
CGK93_RS20065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGK93_RS20070	COG1653	transport
CGK93_RS20075	COG1175	transmembrane transport
CGK93_RS20080	COG0395	ABC-type sugar transport system, permease component
CGK93_RS20100	COG0154	amidase activity
CGK93_RS20105	COG2957	Belongs to the agmatine deiminase family
CGK93_RS20135	COG0789	Transcriptional regulator
CGK93_RS20140	COG0484	heat shock protein binding
CGK93_RS20145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CGK93_RS20150	COG0443	Heat shock 70 kDa protein
CGK93_RS20155	COG3739	integral membrane protein
CGK93_RS20200	COG3119	arylsulfatase activity
CGK93_RS20210	COG1175	transmembrane transport
CGK93_RS20215	COG0395	ABC-type sugar transport system, permease component
CGK93_RS20225	COG1940	carbohydrate kinase activity
CGK93_RS20250	COG1609	Transcriptional regulator
CGK93_RS20260	COG1653	transport
CGK93_RS20275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGK93_RS20290	COG3540	Alkaline phosphatase
CGK93_RS20330	COG3226	Transcriptional regulator
CGK93_RS20335	COG1280	lysine exporter protein (LysE YggA)
CGK93_RS20365	COG2409	Drug exporters of the RND superfamily
CGK93_RS20375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CGK93_RS20380	COG3795	YCII-related domain
CGK93_RS20385	COG4941	Belongs to the sigma-70 factor family
CGK93_RS20390	COG0667	Aldo Keto reductase
CGK93_RS20400	COG1280	lysine exporter protein (LysE YggA)
CGK93_RS20410	COG1609	Transcriptional regulator
CGK93_RS20415	COG1957	nucleoside hydrolase
CGK93_RS20420	COG0477	Major facilitator Superfamily
CGK93_RS20425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGK93_RS20435	COG1309	transcriptional regulator
CGK93_RS20440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGK93_RS20450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGK93_RS20460	COG0833	amino acid
CGK93_RS20465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGK93_RS20475	COG2986	histidine ammonia-lyase
CGK93_RS20510	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGK93_RS20515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGK93_RS20550	COG1122	ATPase activity
CGK93_RS20555	COG4721	ABC-type cobalt transport system, permease component
CGK93_RS20570	COG1320	monovalent cation:proton antiporter activity
CGK93_RS20575	COG2212	antiporter activity
CGK93_RS20585	COG0651	ATP synthesis coupled electron transport
CGK93_RS20590	COG1006	Multisubunit Na H antiporter MnhC subunit
CGK93_RS20595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CGK93_RS20595	COG2111	Na H antiporter
CGK93_RS20610	COG0475	glutathione-regulated potassium exporter activity
CGK93_RS20620	COG0717	Belongs to the dCTP deaminase family
CGK93_RS20650	COG0686	Belongs to the AlaDH PNT family
CGK93_RS20660	COG0583	DNA-binding transcription factor activity
CGK93_RS20675	COG2755	lipolytic protein G-D-S-L family
CGK93_RS20675	COG0657	acetylesterase activity
CGK93_RS20680	COG1609	Transcriptional regulator
CGK93_RS20685	COG0673	inositol 2-dehydrogenase activity
CGK93_RS20730	COG2115	Belongs to the xylose isomerase family
CGK93_RS20735	COG1070	Carbohydrate kinase
CGK93_RS20740	COG1609	Transcriptional regulator
CGK93_RS20755	COG2160	L-arabinose isomerase activity
CGK93_RS20760	COG2017	converts alpha-aldose to the beta-anomer
CGK93_RS20785	COG3347	Dehydrogenase
CGK93_RS20785	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS20790	COG1070	Carbohydrate kinase
CGK93_RS20795	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CGK93_RS20830	COG3387	PFAM Glycoside hydrolase 15-related
CGK93_RS20835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_RS20840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_RS20845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGK93_RS20865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_RS20875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_RS20885	COG1126	abc transporter atp-binding protein
CGK93_RS20890	COG0765	amino acid transport
CGK93_RS20905	COG0433	COG0433 Predicted ATPase
CGK93_RS20920	COG3336	cytochrome c oxidase
CGK93_RS20925	COG0776	regulation of translation
CGK93_RS20980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CGK93_RS20985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CGK93_RS20990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CGK93_RS21025	COG1120	ATPase activity
CGK93_RS21030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_RS21035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_RS21075	COG3012	SEC-C Motif Domain Protein
CGK93_RS21090	COG0667	Aldo Keto reductase
CGK93_RS21130	COG2186	Transcriptional regulator
CGK93_RS21140	COG1027	Aspartate ammonia-lyase
CGK93_RS21150	COG2186	Transcriptional regulator
CGK93_RS21155	COG3618	amidohydrolase
CGK93_RS21165	COG3254	rhamnose metabolic process
CGK93_RS21175	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_RS21185	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS21190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGK93_RS21205	COG4221	oxidoreductase activity
CGK93_RS21215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CGK93_RS21220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CGK93_RS21245	COG0640	Transcriptional regulator
CGK93_RS21260	COG2197	response regulator
CGK93_RS21265	COG4585	Histidine kinase
CGK93_RS21275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGK93_RS21300	COG1760	l-serine dehydratase
CGK93_RS21315	COG0281	malic enzyme
CGK93_RS21320	COG1309	transcriptional regulator
CGK93_RS21360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CGK93_RS21365	COG0477	Major facilitator Superfamily
CGK93_RS21370	COG2986	histidine ammonia-lyase
CGK93_RS21375	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CGK93_RS21405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGK93_RS21415	COG0477	Major facilitator Superfamily
CGK93_RS21420	COG2814	Major facilitator Superfamily
CGK93_RS21425	COG1846	Transcriptional regulator
CGK93_RS21460	COG1113	amino acid transport
CGK93_RS21465	COG4604	ABC transporter, ATP-binding protein
CGK93_RS21470	COG4605	iron ion homeostasis
CGK93_RS21475	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_RS21485	COG0246	Mannitol dehydrogenase
CGK93_RS21490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGK93_RS21490	COG2213	PTS system mannitol-specific
CGK93_RS21500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGK93_RS21505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGK93_RS21535	COG1793	dna ligase
CGK93_RS21550	COG0686	Belongs to the AlaDH PNT family
CGK93_RS21565	COG0673	inositol 2-dehydrogenase activity
CGK93_RS21575	COG2161	toxin-antitoxin pair type II binding
CGK93_RS21600	COG1309	transcriptional regulator
CGK93_RS21635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGK93_RS21650	COG0531	amino acid
CGK93_RS21665	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_RS21670	COG0022	dehydrogenase e1 component
CGK93_RS21680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGK93_RS21685	COG1950	PFAM Membrane protein of
CGK93_RS21700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CGK93_RS21715	COG1607	acyl-coa hydrolase
CGK93_RS21735	COG3971	2-oxopent-4-enoate hydratase activity
CGK93_RS21750	COG1802	Transcriptional regulator
CGK93_RS21755	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_RS21775	COG2261	transglycosylase associated protein
CGK93_RS21785	COG3708	Transcriptional regulator
CGK93_RS21785	COG2207	Transcriptional regulator
CGK93_RS21790	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS21855	COG1609	Transcriptional regulator
CGK93_RS21870	COG0395	ABC-type sugar transport system, permease component
CGK93_RS21875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_RS21920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CGK93_RS21970	COG2207	Transcriptional regulator
CGK93_RS21975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CGK93_RS21985	COG4209	transmembrane transport
CGK93_RS21990	COG0395	ABC-type sugar transport system, permease component
CGK93_RS22025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGK93_RS22030	COG0395	ABC-type sugar transport system, permease component
CGK93_RS22035	COG1175	transmembrane transport
CGK93_RS22060	COG2188	Transcriptional regulator
CGK93_RS22065	COG0673	inositol 2-dehydrogenase activity
CGK93_RS22090	COG0492	ferredoxin-NADP+ reductase activity
CGK93_RS22130	COG0800	Aldolase
CGK93_RS22135	COG1940	carbohydrate kinase activity
CGK93_RS22140	COG2188	Transcriptional regulator
CGK93_RS22150	COG4214	carbohydrate transport
CGK93_RS22155	COG4213	ABC transporter substrate-binding protein
CGK93_RS22160	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS22170	COG2186	Transcriptional regulator
CGK93_RS22175	COG0673	inositol 2-dehydrogenase activity
CGK93_RS22190	COG0673	inositol 2-dehydrogenase activity
CGK93_RS22215	COG0395	ABC-type sugar transport system, permease component
CGK93_RS22220	COG4209	transmembrane transport
CGK93_RS22240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGK93_RS22270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGK93_RS22290	COG1396	sequence-specific DNA binding
CGK93_RS22300	COG0604	alcohol dehydrogenase
CGK93_RS22310	COG3387	PFAM Glycoside hydrolase 15-related
CGK93_RS22320	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CGK93_RS22325	COG0477	Major facilitator Superfamily
CGK93_RS22330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_RS22335	COG1063	alcohol dehydrogenase
CGK93_RS22340	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_RS22345	COG0800	Aldolase
CGK93_RS22355	COG1414	Transcriptional regulator
CGK93_RS22375	COG1414	Transcriptional regulator
CGK93_RS22380	COG2814	Major facilitator Superfamily
CGK93_RS22415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGK93_RS22425	COG2909	trisaccharide binding
CGK93_RS22430	COG0490	domain, Protein
CGK93_RS22430	COG0471	metal ion transport
CGK93_RS22435	COG0477	Major facilitator Superfamily
CGK93_RS22440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CGK93_RS22445	COG2261	transglycosylase associated protein
CGK93_RS22450	COG0515	serine threonine protein kinase
CGK93_RS22460	COG1846	Transcriptional regulator
CGK93_RS22490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CGK93_RS22495	COG1760	l-serine dehydratase
CGK93_RS22500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGK93_RS22505	COG0509	glycine decarboxylation via glycine cleavage system
CGK93_RS22510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGK93_RS22515	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGK93_RS22515	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGK93_RS22520	COG1970	mechanosensitive ion channel activity
CGK93_RS22570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGK93_RS22600	COG2814	Major facilitator Superfamily
CGK93_RS22625	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_RS22630	COG0251	oxidation-reduction process
CGK93_RS22640	COG1414	Transcriptional regulator
CGK93_RS22645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CGK93_RS22655	COG0183	Belongs to the thiolase family
CGK93_RS22660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGK93_RS22680	COG3485	protocatechuate 3,4-dioxygenase
CGK93_RS22690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGK93_RS22695	COG1414	Transcriptional regulator
CGK93_RS22700	COG0477	Major facilitator Superfamily
CGK93_RS22715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CGK93_RS22725	COG3706	GGDEF domain
CGK93_RS22735	COG0583	DNA-binding transcription factor activity
CGK93_RS22770	COG0463	Glycosyl transferase, family 2
CGK93_RS22795	COG0366	Alpha amylase catalytic
CGK93_RS22810	COG2326	polyphosphate kinase activity
CGK93_RS22830	COG1737	Transcriptional regulator
CGK93_RS22835	COG3876	Protein conserved in bacteria
CGK93_RS22840	COG1472	Belongs to the glycosyl hydrolase 3 family
CGK93_RS22880	COG1937	Protein conserved in bacteria
CGK93_RS22950	COG2259	Doxx family
CGK93_RS22960	COG3848	Pyruvate phosphate dikinase
CGK93_RS22960	COG0574	Belongs to the PEP-utilizing enzyme family
CGK93_RS22970	COG1607	acyl-coa hydrolase
CGK93_RS22980	COG0745	RESPONSE REGULATOR receiver
CGK93_RS22985	COG3850	Histidine kinase
CGK93_RS22985	COG0642	Histidine kinase
CGK93_RS23000	COG0305	Participates in initiation and elongation during chromosome replication
CGK93_RS23045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CGK93_RS23050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CGK93_RS23090	COG1414	Transcriptional regulator
CGK93_RS23095	COG1131	(ABC) transporter
CGK93_RS23105	COG0384	phenazine biosynthesis protein PhzF
CGK93_RS23115	COG0359	binds to the 23S rRNA
CGK93_RS23120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CGK93_RS23130	COG0360	Binds together with S18 to 16S ribosomal RNA
CGK93_RS23135	COG1742	UPF0060 membrane protein
CGK93_RS23150	COG1113	amino acid transport
CGK93_RS23155	COG1362	aminopeptidase activity
CGK93_RS23175	COG1414	Transcriptional regulator
CGK93_RS23190	COG0833	amino acid
CGK93_RS23200	COG2197	response regulator
CGK93_RS23205	COG4585	Histidine kinase
CGK93_RS23215	COG1131	(ABC) transporter
CGK93_RS23220	COG1597	lipid kinase activity
CGK93_RS23230	COG0738	Major facilitator superfamily
CGK93_RS23250	COG0768	penicillin binding
CGK93_RS23255	COG1501	Belongs to the glycosyl hydrolase 31 family
CGK93_RS23260	COG2197	response regulator
CGK93_RS23265	COG4585	Histidine kinase
CGK93_RS23275	COG1136	(ABC) transporter
CGK93_RS23280	COG1733	regulation of RNA biosynthetic process
CGK93_RS23285	COG2910	NAD(P)H-binding
CGK93_RS23300	COG0406	alpha-ribazole phosphatase activity
CGK93_RS23305	COG0617	tRNA 3'-terminal CCA addition
CGK93_RS23325	COG0492	ferredoxin-NADP+ reductase activity
CGK93_RS23330	COG3118	belongs to the thioredoxin family
CGK93_RS23345	COG1192	Involved in chromosome partitioning
CGK93_RS23350	COG0357	Ribosomal RNA small subunit methyltransferase G
CGK93_RS23360	COG0706	membrane insertase activity
CGK93_RS23365	COG0759	Could be involved in insertion of integral membrane proteins into the membrane