locus-tag	class	description
ARZXY2_RS00040	COG0776	regulation of translation
ARZXY2_RS00060	COG0433	COG0433 Predicted ATPase
ARZXY2_RS00075	COG0765	amino acid transport
ARZXY2_RS00080	COG1126	abc transporter atp-binding protein
ARZXY2_RS00090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARZXY2_RS00105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ARZXY2_RS00115	COG1937	Protein conserved in bacteria
ARZXY2_RS00135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARZXY2_RS00145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_RS00165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARZXY2_RS00170	COG3387	PFAM Glycoside hydrolase 15-related
ARZXY2_RS00180	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ARZXY2_RS00195	COG1070	Carbohydrate kinase
ARZXY2_RS00200	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS00200	COG3347	Dehydrogenase
ARZXY2_RS00205	COG4952	isomerase
ARZXY2_RS00210	COG3254	rhamnose metabolic process
ARZXY2_RS00215	COG1609	Transcriptional regulator
ARZXY2_RS00220	COG2017	converts alpha-aldose to the beta-anomer
ARZXY2_RS00225	COG2160	L-arabinose isomerase activity
ARZXY2_RS00240	COG1609	Transcriptional regulator
ARZXY2_RS00245	COG1070	Carbohydrate kinase
ARZXY2_RS00250	COG2115	Belongs to the xylose isomerase family
ARZXY2_RS00275	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS00280	COG1609	Transcriptional regulator
ARZXY2_RS00295	COG0583	DNA-binding transcription factor activity
ARZXY2_RS00335	COG0717	Belongs to the dCTP deaminase family
ARZXY2_RS00345	COG0475	glutathione-regulated potassium exporter activity
ARZXY2_RS00360	COG2111	Na H antiporter
ARZXY2_RS00360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ARZXY2_RS00365	COG1006	Multisubunit Na H antiporter MnhC subunit
ARZXY2_RS00370	COG0651	ATP synthesis coupled electron transport
ARZXY2_RS00380	COG2212	antiporter activity
ARZXY2_RS00385	COG1320	monovalent cation:proton antiporter activity
ARZXY2_RS00400	COG4721	ABC-type cobalt transport system, permease component
ARZXY2_RS00405	COG1122	ATPase activity
ARZXY2_RS00430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ARZXY2_RS00435	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARZXY2_RS00465	COG2986	histidine ammonia-lyase
ARZXY2_RS00475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ARZXY2_RS00480	COG0833	amino acid
ARZXY2_RS00490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ARZXY2_RS00500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARZXY2_RS00505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARZXY2_RS00510	COG0477	Major facilitator Superfamily
ARZXY2_RS00515	COG1957	nucleoside hydrolase
ARZXY2_RS00520	COG1609	Transcriptional regulator
ARZXY2_RS00525	COG1280	lysine exporter protein (LysE YggA)
ARZXY2_RS00540	COG0667	Aldo Keto reductase
ARZXY2_RS00545	COG4941	Belongs to the sigma-70 factor family
ARZXY2_RS00550	COG3795	YCII-related domain
ARZXY2_RS00555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ARZXY2_RS00565	COG2409	Drug exporters of the RND superfamily
ARZXY2_RS00570	COG0492	ferredoxin-NADP+ reductase activity
ARZXY2_RS00575	COG2026	Addiction module toxin, RelE StbE family
ARZXY2_RS00580	COG2161	toxin-antitoxin pair type II binding
ARZXY2_RS00590	COG1280	lysine exporter protein (LysE YggA)
ARZXY2_RS00610	COG1064	alcohol dehydrogenase
ARZXY2_RS00615	COG0436	Aminotransferase
ARZXY2_RS00675	COG3540	Alkaline phosphatase
ARZXY2_RS00685	COG0477	Major facilitator Superfamily
ARZXY2_RS00715	COG3739	integral membrane protein
ARZXY2_RS00720	COG0443	Heat shock 70 kDa protein
ARZXY2_RS00725	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ARZXY2_RS00730	COG0484	heat shock protein binding
ARZXY2_RS00735	COG0789	Transcriptional regulator
ARZXY2_RS00740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARZXY2_RS00745	COG1879	ABC-type sugar transport system periplasmic component
ARZXY2_RS00750	COG1129	ABC transporter
ARZXY2_RS00755	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_RS00760	COG1082	Xylose isomerase domain protein TIM barrel
ARZXY2_RS00770	COG1737	Transcriptional regulator
ARZXY2_RS00775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARZXY2_RS00780	COG2140	Oxalate decarboxylase
ARZXY2_RS00790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ARZXY2_RS00795	COG1063	alcohol dehydrogenase
ARZXY2_RS00800	COG1063	alcohol dehydrogenase
ARZXY2_RS00810	COG0800	Aldolase
ARZXY2_RS00840	COG4221	oxidoreductase activity
ARZXY2_RS00845	COG0477	Major facilitator Superfamily
ARZXY2_RS00860	COG1105	Belongs to the carbohydrate kinase PfkB family
ARZXY2_RS00865	COG3958	Transketolase
ARZXY2_RS00870	COG3959	Transketolase, thiamine diphosphate binding domain
ARZXY2_RS00875	COG1063	alcohol dehydrogenase
ARZXY2_RS00920	COG3177	Filamentation induced by cAMP protein fic
ARZXY2_RS00935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ARZXY2_RS00970	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ARZXY2_RS00975	COG2807	transmembrane transport
ARZXY2_RS00980	COG0477	Major facilitator Superfamily
ARZXY2_RS00985	COG1473	amidohydrolase
ARZXY2_RS00995	COG2813	Specifically methylates the guanine in position
ARZXY2_RS01020	COG2076	Multidrug Resistance protein
ARZXY2_RS01025	COG2076	Multidrug Resistance protein
ARZXY2_RS01035	COG0135	phosphoribosylanthranilate isomerase activity
ARZXY2_RS01045	COG3304	Inner membrane component domain
ARZXY2_RS01065	COG3585	molybdate ion transport
ARZXY2_RS01090	COG0542	response to heat
ARZXY2_RS01125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ARZXY2_RS01150	COG0671	phosphoesterase, PA-phosphatase related
ARZXY2_RS01155	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ARZXY2_RS01175	COG3415	Transposase
ARZXY2_RS01175	COG2801	Transposase and inactivated derivatives
ARZXY2_RS01195	COG1366	Belongs to the anti-sigma-factor antagonist family
ARZXY2_RS01205	COG0745	RESPONSE REGULATOR receiver
ARZXY2_RS01220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ARZXY2_RS01225	COG1929	Belongs to the glycerate kinase type-1 family
ARZXY2_RS01230	COG3960	tartronate-semialdehyde synthase activity
ARZXY2_RS01235	COG2084	Dehydrogenase
ARZXY2_RS01240	COG3622	Belongs to the hyi family
ARZXY2_RS01265	COG1609	Transcriptional regulator
ARZXY2_RS01270	COG1653	transport
ARZXY2_RS01285	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS01295	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS01315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ARZXY2_RS01355	COG0405	Gamma-glutamyltransferase
ARZXY2_RS01440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ARZXY2_RS01445	COG3311	Transcriptional regulator
ARZXY2_RS01465	COG0300	oxidoreductase activity
ARZXY2_RS01475	COG3401	FG-GAP repeat protein
ARZXY2_RS01485	COG0563	adenylate kinase activity
ARZXY2_RS01505	COG0659	secondary active sulfate transmembrane transporter activity
ARZXY2_RS01530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ARZXY2_RS01535	COG4585	Histidine kinase
ARZXY2_RS01540	COG2318	DinB family
ARZXY2_RS01555	COG3257	ureidoglycine aminohydrolase activity
ARZXY2_RS01565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ARZXY2_RS01575	COG1414	Transcriptional regulator
ARZXY2_RS01580	COG2233	PERMEase
ARZXY2_RS01605	COG0590	tRNA wobble adenosine to inosine editing
ARZXY2_RS01610	COG2252	PERMEase
ARZXY2_RS01615	COG3608	succinylglutamate desuccinylase aspartoacylase
ARZXY2_RS01615	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ARZXY2_RS01625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ARZXY2_RS01640	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ARZXY2_RS01645	COG1953	Uracil, thiamine, allantoin
ARZXY2_RS01655	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS01675	COG0151	Belongs to the GarS family
ARZXY2_RS01680	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ARZXY2_RS01700	COG1132	(ABC) transporter
ARZXY2_RS01705	COG1132	(ABC) transporter
ARZXY2_RS01710	COG1408	metallophosphoesterase
ARZXY2_RS01715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ARZXY2_RS01740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ARZXY2_RS01755	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS01760	COG1175	transmembrane transport
ARZXY2_RS01770	COG1609	Transcriptional regulator
ARZXY2_RS01780	COG1136	(ABC) transporter
ARZXY2_RS01780	COG0577	efflux transmembrane transporter activity
ARZXY2_RS01785	COG1349	DNA-binding transcription factor activity
ARZXY2_RS01790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARZXY2_RS01860	COG1111	helicase
ARZXY2_RS01860	COG1205	dead DEAH box helicase
ARZXY2_RS01870	COG1054	Belongs to the UPF0176 family
ARZXY2_RS01885	COG2890	protein-(glutamine-N5) methyltransferase activity
ARZXY2_RS01895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ARZXY2_RS01895	COG1754	DNA topoisomerase type I activity
ARZXY2_RS01905	COG0248	Ppx GppA phosphatase
ARZXY2_RS01910	COG1082	Xylose isomerase domain protein TIM barrel
ARZXY2_RS01915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ARZXY2_RS01920	COG0569	domain protein
ARZXY2_RS01925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ARZXY2_RS01930	COG0123	including yeast histone deacetylase and acetoin utilization protein
ARZXY2_RS01940	COG0640	Transcriptional regulator
ARZXY2_RS01945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ARZXY2_RS01960	COG1609	Transcriptional regulator
ARZXY2_RS01965	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS01975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARZXY2_RS01980	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_RS02010	COG1175	transmembrane transport
ARZXY2_RS02015	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS02035	COG1175	transmembrane transport
ARZXY2_RS02040	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS02050	COG2814	Major facilitator Superfamily
ARZXY2_RS02055	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS02060	COG5578	integral membrane protein
ARZXY2_RS02070	COG1653	transport
ARZXY2_RS02075	COG4209	transmembrane transport
ARZXY2_RS02080	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS02085	COG2755	lipolytic protein G-D-S-L family
ARZXY2_RS02095	COG3458	cephalosporin-C deacetylase activity
ARZXY2_RS02100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ARZXY2_RS02125	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ARZXY2_RS02145	COG0406	alpha-ribazole phosphatase activity
ARZXY2_RS02155	COG0785	Cytochrome C biogenesis protein
ARZXY2_RS02165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ARZXY2_RS02170	COG0443	Heat shock 70 kDa protein
ARZXY2_RS02220	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ARZXY2_RS02230	COG1266	CAAX protease self-immunity
ARZXY2_RS02235	COG0803	Belongs to the bacterial solute-binding protein 9 family
ARZXY2_RS02240	COG1121	(ABC) transporter
ARZXY2_RS02245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ARZXY2_RS02250	COG0488	(ABC) transporter
ARZXY2_RS02275	COG0183	Belongs to the thiolase family
ARZXY2_RS02280	COG1024	Enoyl-CoA hydratase
ARZXY2_RS02285	COG1250	3-hydroxyacyl-CoA dehydrogenase
ARZXY2_RS02300	COG1216	Glycosyl transferase, family 2
ARZXY2_RS02305	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_RS02305	COG2030	dehydratase
ARZXY2_RS02325	COG2050	protein possibly involved in aromatic compounds catabolism
ARZXY2_RS02345	COG5002	protein histidine kinase activity
ARZXY2_RS02365	COG4251	negative regulation of phosphorylation
ARZXY2_RS02365	COG5001	Diguanylate cyclase
ARZXY2_RS02365	COG3706	GGDEF domain
ARZXY2_RS02365	COG2203	Gaf domain
ARZXY2_RS02375	COG1388	LysM domain
ARZXY2_RS02375	COG3942	CHAP domain
ARZXY2_RS02380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARZXY2_RS02385	COG3396	Phenylacetate-CoA oxygenase
ARZXY2_RS02390	COG3460	Phenylacetate-CoA oxygenase
ARZXY2_RS02395	COG3396	Phenylacetate-CoA oxygenase
ARZXY2_RS02400	COG2151	metal-sulfur cluster biosynthetic enzyme
ARZXY2_RS02405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ARZXY2_RS02410	COG1024	Enoyl-CoA hydratase
ARZXY2_RS02415	COG2801	Transposase and inactivated derivatives
ARZXY2_RS02415	COG3415	Transposase
ARZXY2_RS02420	COG1597	lipid kinase activity
ARZXY2_RS02445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ARZXY2_RS02450	COG3979	chitinase
ARZXY2_RS02475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ARZXY2_RS02485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ARZXY2_RS02490	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ARZXY2_RS02510	COG1045	serine acetyltransferase
ARZXY2_RS02520	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ARZXY2_RS02560	COG0489	protein tyrosine kinase activity
ARZXY2_RS02575	COG1316	TRANSCRIPTIONal
ARZXY2_RS02595	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_RS02600	COG1682	transport, permease protein
ARZXY2_RS02605	COG1134	teichoic acid transport
ARZXY2_RS02615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ARZXY2_RS02645	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ARZXY2_RS02670	COG0022	dehydrogenase e1 component
ARZXY2_RS02675	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_RS02700	COG1404	Belongs to the peptidase S8 family
ARZXY2_RS02745	COG1175	transmembrane transport
ARZXY2_RS02750	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS02755	COG1621	beta-fructofuranosidase activity
ARZXY2_RS02760	COG1609	Transcriptional regulator
ARZXY2_RS02775	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_RS02785	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ARZXY2_RS02795	COG0765	amino acid transport
ARZXY2_RS02805	COG1169	isochorismate synthase
ARZXY2_RS02810	COG2226	methyltransferase
ARZXY2_RS02820	COG0142	geranyltranstransferase activity
ARZXY2_RS02835	COG2860	membrane
ARZXY2_RS02845	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ARZXY2_RS02850	COG0175	sulfate reduction
ARZXY2_RS02860	COG2895	sulfate adenylyltransferase (ATP) activity
ARZXY2_RS02865	COG2040	homocysteine
ARZXY2_RS02875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ARZXY2_RS02875	COG1116	anion transmembrane transporter activity
ARZXY2_RS02880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARZXY2_RS02895	COG1733	regulation of RNA biosynthetic process
ARZXY2_RS02905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARZXY2_RS02915	COG1648	precorrin-2 dehydrogenase activity
ARZXY2_RS02915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ARZXY2_RS02925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARZXY2_RS02925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_RS02930	COG2186	Transcriptional regulator
ARZXY2_RS02935	COG2807	transmembrane transport
ARZXY2_RS02940	COG3835	regulator
ARZXY2_RS02945	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_RS02980	COG0531	amino acid
ARZXY2_RS03010	COG0501	Belongs to the peptidase M48B family
ARZXY2_RS03015	COG1666	GTP binding
ARZXY2_RS03030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ARZXY2_RS03050	COG1131	(ABC) transporter
ARZXY2_RS03065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ARZXY2_RS03095	COG1051	belongs to the nudix hydrolase family
ARZXY2_RS03115	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS03120	COG1175	transmembrane transport
ARZXY2_RS03140	COG0754	glutathionylspermidine amidase activity
ARZXY2_RS03175	COG0702	epimerase
ARZXY2_RS03185	COG1940	carbohydrate kinase activity
ARZXY2_RS03195	COG1175	transmembrane transport
ARZXY2_RS03200	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS03205	COG0366	Alpha amylase catalytic
ARZXY2_RS03210	COG4989	oxidoreductase activity
ARZXY2_RS03220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARZXY2_RS03245	COG2030	dehydratase
ARZXY2_RS03255	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ARZXY2_RS03270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ARZXY2_RS03280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ARZXY2_RS03285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ARZXY2_RS03290	COG1725	Transcriptional regulator
ARZXY2_RS03305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ARZXY2_RS03310	COG0456	acetyltransferase
ARZXY2_RS03315	COG0745	RESPONSE REGULATOR receiver
ARZXY2_RS03325	COG3485	protocatechuate 3,4-dioxygenase
ARZXY2_RS03335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ARZXY2_RS03385	COG2197	response regulator
ARZXY2_RS03390	COG0436	Aminotransferase
ARZXY2_RS03400	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ARZXY2_RS03410	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ARZXY2_RS03415	COG0081	regulation of translation
ARZXY2_RS03430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ARZXY2_RS03435	COG0222	ribosome binding
ARZXY2_RS03440	COG0442	prolyl-tRNA aminoacylation
ARZXY2_RS03445	COG0183	Belongs to the thiolase family
ARZXY2_RS03450	COG0085	RNA polymerase activity
ARZXY2_RS03455	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ARZXY2_RS03460	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ARZXY2_RS03465	COG0049	tRNA binding
ARZXY2_RS03470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ARZXY2_RS03475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ARZXY2_RS03485	COG2723	6-phospho-beta-galactosidase activity
ARZXY2_RS03490	COG0051	transcription antitermination factor activity, RNA binding
ARZXY2_RS03495	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ARZXY2_RS03500	COG0088	Forms part of the polypeptide exit tunnel
ARZXY2_RS03505	COG0089	rRNA binding
ARZXY2_RS03510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ARZXY2_RS03515	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ARZXY2_RS03520	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ARZXY2_RS03525	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ARZXY2_RS03530	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ARZXY2_RS03535	COG0255	Belongs to the universal ribosomal protein uL29 family
ARZXY2_RS03540	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ARZXY2_RS03545	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ARZXY2_RS03550	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ARZXY2_RS03555	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ARZXY2_RS03560	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ARZXY2_RS03565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ARZXY2_RS03575	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ARZXY2_RS03580	COG1841	ribosomal large subunit assembly
ARZXY2_RS03585	COG0200	Binds to the 23S rRNA
ARZXY2_RS03595	COG0563	adenylate kinase activity
ARZXY2_RS03600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ARZXY2_RS03605	COG1442	glycosyl transferase family 8
ARZXY2_RS03605	COG1216	Glycosyl transferase, family 2
ARZXY2_RS03615	COG0318	PFAM AMP-dependent synthetase and ligase
ARZXY2_RS03625	COG0024	Methionine aminopeptidase
ARZXY2_RS03645	COG3191	aminopeptidase activity
ARZXY2_RS03650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ARZXY2_RS03655	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ARZXY2_RS03660	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ARZXY2_RS03665	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ARZXY2_RS03670	COG0202	RNA polymerase activity
ARZXY2_RS03675	COG0203	ribosomal protein L17
ARZXY2_RS03680	COG0101	tRNA pseudouridine synthase activity
ARZXY2_RS03700	COG0455	bacterial-type flagellum organization
ARZXY2_RS03730	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ARZXY2_RS03735	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ARZXY2_RS03740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARZXY2_RS03750	COG1072	(Pantothenic acid kinase))
ARZXY2_RS03760	COG0736	holo-[acyl-carrier-protein] synthase activity
ARZXY2_RS03785	COG0667	Aldo Keto reductase
ARZXY2_RS03795	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ARZXY2_RS03800	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_RS03810	COG1486	melibiose metabolic process
ARZXY2_RS03820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ARZXY2_RS03825	COG0802	atpase or kinase
ARZXY2_RS03840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ARZXY2_RS03845	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARZXY2_RS03855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ARZXY2_RS03860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ARZXY2_RS03875	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ARZXY2_RS03880	COG0459	protein refolding
ARZXY2_RS03900	COG1132	(ABC) transporter
ARZXY2_RS03905	COG0516	GMP reductase activity
ARZXY2_RS03925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ARZXY2_RS03945	COG0519	Catalyzes the synthesis of GMP from XMP
ARZXY2_RS03945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ARZXY2_RS03950	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ARZXY2_RS03965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ARZXY2_RS03970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ARZXY2_RS04000	COG1695	Transcriptional regulator
ARZXY2_RS04005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ARZXY2_RS04015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARZXY2_RS04020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARZXY2_RS04025	COG1528	Iron-storage protein
ARZXY2_RS04030	COG0598	Magnesium transport protein CorA
ARZXY2_RS04055	COG3548	integral membrane protein
ARZXY2_RS04070	COG2971	BadF BadG BcrA BcrD
ARZXY2_RS04085	COG1162	GTPase activity
ARZXY2_RS04095	COG1174	glycine betaine transport
ARZXY2_RS04115	COG2326	polyphosphate kinase activity
ARZXY2_RS04120	COG1722	exodeoxyribonuclease VII activity
ARZXY2_RS04125	COG1570	exodeoxyribonuclease VII activity
ARZXY2_RS04135	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ARZXY2_RS04140	COG1322	Protein conserved in bacteria
ARZXY2_RS04145	COG0012	GTP binding
ARZXY2_RS04210	COG0747	negative chemotaxis
ARZXY2_RS04215	COG0601	transmembrane transport
ARZXY2_RS04220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ARZXY2_RS04235	COG1217	gtp-binding protein TYPA
ARZXY2_RS04265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ARZXY2_RS04270	COG3226	Transcriptional regulator
ARZXY2_RS04285	COG2171	N-acyltransferase activity
ARZXY2_RS04290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARZXY2_RS04295	COG0765	amino acid transport
ARZXY2_RS04300	COG0765	amino acid transport
ARZXY2_RS04305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARZXY2_RS04310	COG1126	abc transporter atp-binding protein
ARZXY2_RS04335	COG4122	O-methyltransferase activity
ARZXY2_RS04340	COG1595	DNA-templated transcription, initiation
ARZXY2_RS04350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ARZXY2_RS04365	COG2239	Acts as a magnesium transporter
ARZXY2_RS04375	COG0006	proline dipeptidase activity
ARZXY2_RS04380	COG0613	PHP domain protein
ARZXY2_RS04385	COG2095	MarC family integral membrane protein
ARZXY2_RS04395	COG0513	Belongs to the DEAD box helicase family
ARZXY2_RS04400	COG2801	Transposase and inactivated derivatives
ARZXY2_RS04400	COG3415	Transposase
ARZXY2_RS04415	COG0352	thiamine-phosphate diphosphorylase activity
ARZXY2_RS04420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ARZXY2_RS04420	COG2022	thiamine diphosphate biosynthetic process
ARZXY2_RS04445	COG1309	transcriptional regulator
ARZXY2_RS04455	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ARZXY2_RS04460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ARZXY2_RS04470	COG3253	May function as heme-dependent peroxidase
ARZXY2_RS04475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ARZXY2_RS04480	COG0181	hydroxymethylbilane synthase activity
ARZXY2_RS04490	COG0113	porphobilinogen synthase activity
ARZXY2_RS04500	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ARZXY2_RS04505	COG1472	Belongs to the glycosyl hydrolase 3 family
ARZXY2_RS04515	COG0765	amino acid transport
ARZXY2_RS04520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARZXY2_RS04535	COG1074	ATP-dependent DNA helicase activity
ARZXY2_RS04550	COG2816	NAD+ diphosphatase activity
ARZXY2_RS04570	COG3480	Lon protease (S16) C-terminal proteolytic domain
ARZXY2_RS04575	COG1615	UPF0182 protein
ARZXY2_RS04595	COG1842	Phage shock protein A
ARZXY2_RS04605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ARZXY2_RS04610	COG2086	electron transfer activity
ARZXY2_RS04615	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ARZXY2_RS04620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ARZXY2_RS04625	COG3265	gluconokinase activity
ARZXY2_RS04635	COG1595	DNA-templated transcription, initiation
ARZXY2_RS04640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ARZXY2_RS04645	COG0484	heat shock protein binding
ARZXY2_RS04675	COG0482	sulfurtransferase activity
ARZXY2_RS04695	COG0601	transmembrane transport
ARZXY2_RS04730	COG0714	Associated with various cellular activities
ARZXY2_RS04750	COG0745	RESPONSE REGULATOR receiver
ARZXY2_RS04755	COG5002	protein histidine kinase activity
ARZXY2_RS04755	COG5000	phosphorelay sensor kinase activity
ARZXY2_RS04760	COG5401	PFAM Sporulation and spore germination
ARZXY2_RS04770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ARZXY2_RS04775	COG3214	Protein conserved in bacteria
ARZXY2_RS04780	COG0653	protein targeting
ARZXY2_RS04815	COG2902	Dehydrogenase
ARZXY2_RS04835	COG1674	ftsk spoiiie
ARZXY2_RS04845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ARZXY2_RS04860	COG1216	Glycosyl transferase, family 2
ARZXY2_RS04950	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ARZXY2_RS04955	COG2884	Cell division ATP-binding protein ftsE
ARZXY2_RS04960	COG2177	Part of the ABC transporter FtsEX involved in
ARZXY2_RS04970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ARZXY2_RS05005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ARZXY2_RS05010	COG0483	inositol monophosphate 1-phosphatase activity
ARZXY2_RS05020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ARZXY2_RS05030	COG1595	DNA-templated transcription, initiation
ARZXY2_RS05055	COG0567	Dehydrogenase, E1 component
ARZXY2_RS05055	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_RS05060	COG1253	flavin adenine dinucleotide binding
ARZXY2_RS05070	COG0803	Belongs to the bacterial solute-binding protein 9 family
ARZXY2_RS05075	COG1121	(ABC) transporter
ARZXY2_RS05080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ARZXY2_RS05105	COG1064	alcohol dehydrogenase
ARZXY2_RS05110	COG0537	adenosine 5'-monophosphoramidase activity
ARZXY2_RS05115	COG1643	Atp-dependent helicase
ARZXY2_RS05145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ARZXY2_RS05145	COG1017	nitric oxide dioxygenase activity
ARZXY2_RS05160	COG0018	arginyl-trna synthetase
ARZXY2_RS05165	COG0019	diaminopimelate decarboxylase activity
ARZXY2_RS05170	COG0460	homoserine dehydrogenase
ARZXY2_RS05175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ARZXY2_RS05180	COG0083	homoserine kinase activity
ARZXY2_RS05190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ARZXY2_RS05195	COG2890	protein-(glutamine-N5) methyltransferase activity
ARZXY2_RS05200	COG0009	L-threonylcarbamoyladenylate synthase
ARZXY2_RS05215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ARZXY2_RS05230	COG0356	it plays a direct role in the translocation of protons across the membrane
ARZXY2_RS05235	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ARZXY2_RS05240	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ARZXY2_RS05245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ARZXY2_RS05250	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ARZXY2_RS05255	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ARZXY2_RS05260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ARZXY2_RS05265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ARZXY2_RS05275	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ARZXY2_RS05280	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ARZXY2_RS05290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ARZXY2_RS05295	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ARZXY2_RS05325	COG1902	pentaerythritol trinitrate reductase activity
ARZXY2_RS05340	COG0363	glucosamine-6-phosphate deaminase activity
ARZXY2_RS05355	COG1335	isochorismatase
ARZXY2_RS05365	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ARZXY2_RS05375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ARZXY2_RS05380	COG1234	tRNA 3'-trailer cleavage
ARZXY2_RS05385	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ARZXY2_RS05390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ARZXY2_RS05405	COG1131	(ABC) transporter
ARZXY2_RS05430	COG2149	membrane
ARZXY2_RS05445	COG0420	3'-5' exonuclease activity
ARZXY2_RS05450	COG0419	ATPase involved in DNA repair
ARZXY2_RS05460	COG1414	Transcriptional regulator
ARZXY2_RS05465	COG0477	Major facilitator Superfamily
ARZXY2_RS05485	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_RS05490	COG0022	dehydrogenase e1 component
ARZXY2_RS05500	COG1113	amino acid transport
ARZXY2_RS05505	COG1522	sequence-specific DNA binding
ARZXY2_RS05515	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ARZXY2_RS05520	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ARZXY2_RS05530	COG1104	cysteine desulfurase activity
ARZXY2_RS05545	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ARZXY2_RS05555	COG1305	Transglutaminase-like
ARZXY2_RS05560	COG1846	Transcriptional regulator
ARZXY2_RS05565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARZXY2_RS05570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ARZXY2_RS05575	COG0579	oxidoreductase
ARZXY2_RS05580	COG0747	negative chemotaxis
ARZXY2_RS05610	COG2133	pyrroloquinoline quinone binding
ARZXY2_RS05620	COG0129	dihydroxy-acid dehydratase activity
ARZXY2_RS05630	COG0440	acetolactate synthase activity
ARZXY2_RS05635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ARZXY2_RS05640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARZXY2_RS05650	COG0577	efflux transmembrane transporter activity
ARZXY2_RS05650	COG1136	(ABC) transporter
ARZXY2_RS05665	COG0577	efflux transmembrane transporter activity
ARZXY2_RS05665	COG1136	(ABC) transporter
ARZXY2_RS05670	COG2197	response regulator
ARZXY2_RS05675	COG4585	Histidine kinase
ARZXY2_RS05680	COG0473	3-isopropylmalate dehydrogenase activity
ARZXY2_RS05685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ARZXY2_RS05690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_RS05700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ARZXY2_RS05745	COG1414	Transcriptional regulator
ARZXY2_RS05750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ARZXY2_RS05755	COG0066	3-isopropylmalate dehydratase activity
ARZXY2_RS05760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ARZXY2_RS05770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ARZXY2_RS05775	COG1181	Belongs to the D-alanine--D-alanine ligase family
ARZXY2_RS05790	COG1461	Dihydroxyacetone kinase
ARZXY2_RS05800	COG0742	ribosomal rna small subunit methyltransferase
ARZXY2_RS05815	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ARZXY2_RS05830	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ARZXY2_RS05835	COG0571	ribonuclease III activity
ARZXY2_RS05840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ARZXY2_RS05895	COG2963	transposase activity
ARZXY2_RS05930	COG0210	DNA helicase
ARZXY2_RS06020	COG2132	Multicopper oxidase
ARZXY2_RS06030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ARZXY2_RS06035	COG2226	methyltransferase
ARZXY2_RS06045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ARZXY2_RS06055	COG2132	Multicopper oxidase
ARZXY2_RS06065	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ARZXY2_RS06095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ARZXY2_RS06105	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ARZXY2_RS06150	COG1937	Protein conserved in bacteria
ARZXY2_RS06170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ARZXY2_RS06335	COG0750	zinc metalloprotease
ARZXY2_RS06430	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ARZXY2_RS06505	COG0500	methyltransferase
ARZXY2_RS06515	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS06580	COG0542	response to heat
ARZXY2_RS06590	COG1074	ATP-dependent DNA helicase activity
ARZXY2_RS06665	COG0798	PFAM Bile acid sodium symporter
ARZXY2_RS06675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARZXY2_RS06680	COG0492	ferredoxin-NADP+ reductase activity
ARZXY2_RS06690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARZXY2_RS06695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARZXY2_RS06700	COG0659	secondary active sulfate transmembrane transporter activity
ARZXY2_RS06705	COG0789	Transcriptional regulator
ARZXY2_RS06730	COG1793	dna ligase
ARZXY2_RS06735	COG4974	Belongs to the 'phage' integrase family
ARZXY2_RS06790	COG0085	RNA polymerase activity
ARZXY2_RS06955	COG2814	Major facilitator Superfamily
ARZXY2_RS06970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ARZXY2_RS06995	COG2514	catechol 2,3-dioxygenase activity
ARZXY2_RS07005	COG0228	four-way junction DNA binding
ARZXY2_RS07010	COG1837	Belongs to the UPF0109 family
ARZXY2_RS07015	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ARZXY2_RS07020	COG0336	Belongs to the RNA methyltransferase TrmD family
ARZXY2_RS07025	COG0335	large ribosomal subunit rRNA binding
ARZXY2_RS07030	COG0681	Belongs to the peptidase S26 family
ARZXY2_RS07040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ARZXY2_RS07050	COG0792	nuclease activity
ARZXY2_RS07130	COG1473	amidohydrolase
ARZXY2_RS07140	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ARZXY2_RS07145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ARZXY2_RS07160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ARZXY2_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS07175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ARZXY2_RS07180	COG2124	cytochrome p450
ARZXY2_RS07200	COG0512	Glutamine amidotransferase of anthranilate synthase
ARZXY2_RS07215	COG0686	Belongs to the AlaDH PNT family
ARZXY2_RS07230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ARZXY2_RS07255	COG2149	membrane
ARZXY2_RS07275	COG2814	Major facilitator Superfamily
ARZXY2_RS07285	COG0456	acetyltransferase
ARZXY2_RS07310	COG4974	Belongs to the 'phage' integrase family
ARZXY2_RS07325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ARZXY2_RS07330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ARZXY2_RS07345	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ARZXY2_RS07375	COG3415	Transposase
ARZXY2_RS07375	COG2801	Transposase and inactivated derivatives
ARZXY2_RS07390	COG0477	Major facilitator Superfamily
ARZXY2_RS07400	COG2084	Dehydrogenase
ARZXY2_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS07410	COG1063	alcohol dehydrogenase
ARZXY2_RS07420	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ARZXY2_RS07425	COG1045	serine acetyltransferase
ARZXY2_RS07435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ARZXY2_RS07440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ARZXY2_RS07450	COG3022	response to hydroperoxide
ARZXY2_RS07480	COG0242	peptide deformylase activity
ARZXY2_RS07505	COG0629	single-stranded DNA binding
ARZXY2_RS07525	COG1946	Acyl-CoA thioesterase
ARZXY2_RS07540	COG0668	transmembrane transport
ARZXY2_RS07585	COG0544	peptidyl-prolyl cis-trans isomerase activity
ARZXY2_RS07590	COG0740	serine-type endopeptidase activity
ARZXY2_RS07595	COG0740	serine-type endopeptidase activity
ARZXY2_RS07600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ARZXY2_RS07605	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ARZXY2_RS07610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ARZXY2_RS07615	COG0525	valine-tRNA ligase activity
ARZXY2_RS07635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ARZXY2_RS07640	COG0285	dihydrofolate synthase activity
ARZXY2_RS07650	COG0105	UTP biosynthetic process
ARZXY2_RS07660	COG1530	ribonuclease E activity
ARZXY2_RS07665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ARZXY2_RS07665	COG0352	thiamine-phosphate diphosphorylase activity
ARZXY2_RS07665	COG0351	phosphomethylpyrimidine kinase
ARZXY2_RS07670	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ARZXY2_RS07675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ARZXY2_RS07680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ARZXY2_RS07685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ARZXY2_RS07690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ARZXY2_RS07700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ARZXY2_RS07710	COG0799	negative regulation of ribosome biogenesis
ARZXY2_RS07730	COG2813	Specifically methylates the guanine in position
ARZXY2_RS07745	COG0714	Associated with various cellular activities
ARZXY2_RS07785	COG0583	DNA-binding transcription factor activity
ARZXY2_RS07795	COG1780	Probably involved in ribonucleotide reductase function
ARZXY2_RS07800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ARZXY2_RS07805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ARZXY2_RS07840	COG4804	nuclease activity
ARZXY2_RS07875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_RS07890	COG2135	peptidase activity
ARZXY2_RS07915	COG0587	DNA-directed DNA polymerase activity
ARZXY2_RS07920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ARZXY2_RS07930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ARZXY2_RS07935	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ARZXY2_RS07940	COG0339	signal peptide processing
ARZXY2_RS07960	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ARZXY2_RS07965	COG0217	transcriptional regulatory protein
ARZXY2_RS07970	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ARZXY2_RS07975	COG0632	four-way junction helicase activity
ARZXY2_RS07980	COG2255	four-way junction helicase activity
ARZXY2_RS07990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ARZXY2_RS07995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ARZXY2_RS08000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ARZXY2_RS08010	COG1196	nuclear chromosome segregation
ARZXY2_RS08020	COG0124	histidyl-tRNA synthetase
ARZXY2_RS08025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ARZXY2_RS08045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ARZXY2_RS08060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ARZXY2_RS08075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ARZXY2_RS08080	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ARZXY2_RS08085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ARZXY2_RS08090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ARZXY2_RS08100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ARZXY2_RS08105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ARZXY2_RS08115	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ARZXY2_RS08120	COG0540	Belongs to the ATCase OTCase family
ARZXY2_RS08125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ARZXY2_RS08135	COG0505	Belongs to the CarA family
ARZXY2_RS08140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ARZXY2_RS08145	COG0284	orotidine-5'-phosphate decarboxylase activity
ARZXY2_RS08155	COG0194	GDP metabolic process
ARZXY2_RS08160	COG1758	RNA polymerase activity
ARZXY2_RS08170	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ARZXY2_RS08185	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_RS08195	COG0656	L-ascorbic acid biosynthetic process
ARZXY2_RS08200	COG2390	Transcriptional regulator
ARZXY2_RS08205	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ARZXY2_RS08210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ARZXY2_RS08215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ARZXY2_RS08220	COG0495	leucyl-tRNA aminoacylation
ARZXY2_RS08225	COG1307	EDD domain protein, DegV family
ARZXY2_RS08245	COG0268	Binds directly to 16S ribosomal RNA
ARZXY2_RS08255	COG0481	GTPase activity
ARZXY2_RS08275	COG1420	regulation of RNA biosynthetic process
ARZXY2_RS08280	COG0484	heat shock protein binding
ARZXY2_RS08305	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ARZXY2_RS08315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ARZXY2_RS08320	COG1316	TRANSCRIPTIONal
ARZXY2_RS08325	COG3590	peptidase
ARZXY2_RS08330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ARZXY2_RS08335	COG1381	Involved in DNA repair and RecF pathway recombination
ARZXY2_RS08340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ARZXY2_RS08345	COG2267	carboxylic ester hydrolase activity
ARZXY2_RS08360	COG0167	dihydroorotate dehydrogenase activity
ARZXY2_RS08380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ARZXY2_RS08385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ARZXY2_RS08395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ARZXY2_RS08400	COG2186	Transcriptional regulator
ARZXY2_RS08405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ARZXY2_RS08410	COG0723	plastoquinol--plastocyanin reductase activity
ARZXY2_RS08415	COG2010	Cytochrome c
ARZXY2_RS08420	COG1845	cytochrome c oxidase, subunit III
ARZXY2_RS08425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ARZXY2_RS08480	COG1126	abc transporter atp-binding protein
ARZXY2_RS08490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARZXY2_RS08495	COG2188	Transcriptional regulator
ARZXY2_RS08535	COG0667	Aldo Keto reductase
ARZXY2_RS08545	COG3424	synthase
ARZXY2_RS08550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ARZXY2_RS08565	COG0242	peptide deformylase activity
ARZXY2_RS08570	COG4946	Tricorn protease homolog
ARZXY2_RS08570	COG1506	peptidase
ARZXY2_RS08570	COG0823	Involved in the tonB-independent uptake of proteins
ARZXY2_RS08575	COG2226	methyltransferase
ARZXY2_RS08595	COG1216	Glycosyl transferase, family 2
ARZXY2_RS08600	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ARZXY2_RS08605	COG4581	dead DEAH box helicase
ARZXY2_RS08610	COG0805	protein transport
ARZXY2_RS08615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ARZXY2_RS08635	COG0545	Peptidyl-prolyl cis-trans isomerase
ARZXY2_RS08640	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ARZXY2_RS08645	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ARZXY2_RS08650	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ARZXY2_RS08660	COG4122	O-methyltransferase activity
ARZXY2_RS08665	COG1222	aaa ATPase
ARZXY2_RS08680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARZXY2_RS08690	COG0215	cysteine-tRNA ligase activity
ARZXY2_RS08695	COG1968	undecaprenyl-diphosphatase activity
ARZXY2_RS08700	COG0656	L-ascorbic acid biosynthetic process
ARZXY2_RS08705	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ARZXY2_RS08710	COG1088	dTDP-glucose 4,6-dehydratase activity
ARZXY2_RS08780	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS08785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ARZXY2_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS08825	COG0183	Belongs to the thiolase family
ARZXY2_RS08835	COG1960	acyl-CoA dehydrogenase activity
ARZXY2_RS08840	COG0297	glycogen (starch) synthase activity
ARZXY2_RS08845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ARZXY2_RS08855	COG1305	Transglutaminase-like
ARZXY2_RS08880	COG0254	rRNA binding
ARZXY2_RS08895	COG1119	ATPase activity
ARZXY2_RS08900	COG0560	Phosphoserine phosphatase
ARZXY2_RS08900	COG3830	Belongs to the UPF0237 family
ARZXY2_RS08910	COG1129	ABC transporter
ARZXY2_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS08945	COG0488	(ABC) transporter
ARZXY2_RS08950	COG1268	BioY protein
ARZXY2_RS08955	COG1122	ATPase activity
ARZXY2_RS08970	COG0318	PFAM AMP-dependent synthetase and ligase
ARZXY2_RS08980	COG2151	metal-sulfur cluster biosynthetic enzyme
ARZXY2_RS08985	COG0396	ATPase activity
ARZXY2_RS09010	COG1131	(ABC) transporter
ARZXY2_RS09020	COG1612	heme a metabolic process
ARZXY2_RS09025	COG0109	protoheme IX farnesyltransferase activity
ARZXY2_RS09035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ARZXY2_RS09040	COG0166	Belongs to the GPI family
ARZXY2_RS09055	COG0363	glucosamine-6-phosphate deaminase activity
ARZXY2_RS09060	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ARZXY2_RS09065	COG0149	triose-phosphate isomerase activity
ARZXY2_RS09070	COG0126	phosphoglycerate kinase activity
ARZXY2_RS09075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ARZXY2_RS09080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ARZXY2_RS09085	COG1481	regulation of sporulation
ARZXY2_RS09095	COG1660	Displays ATPase and GTPase activities
ARZXY2_RS09100	COG0322	excinuclease ABC activity
ARZXY2_RS09110	COG0546	phosphoglycolate phosphatase activity
ARZXY2_RS09125	COG4106	trans-aconitate 2-methyltransferase activity
ARZXY2_RS09135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ARZXY2_RS09160	COG0556	nucleotide-excision repair
ARZXY2_RS09165	COG0237	dephospho-CoA kinase activity
ARZXY2_RS09165	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ARZXY2_RS09170	COG1739	Uncharacterized protein family UPF0029
ARZXY2_RS09175	COG0539	negative regulation of cytoplasmic translation
ARZXY2_RS09180	COG4552	Acetyltransferase involved in intracellular survival and related
ARZXY2_RS09190	COG2050	protein possibly involved in aromatic compounds catabolism
ARZXY2_RS09225	COG3483	tryptophan 2,3-dioxygenase activity
ARZXY2_RS09240	COG2971	BadF BadG BcrA BcrD
ARZXY2_RS09260	COG0009	L-threonylcarbamoyladenylate synthase
ARZXY2_RS09290	COG1643	Atp-dependent helicase
ARZXY2_RS09295	COG1064	alcohol dehydrogenase
ARZXY2_RS09310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ARZXY2_RS09335	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ARZXY2_RS09350	COG1793	dna ligase
ARZXY2_RS09350	COG3285	dna ligase
ARZXY2_RS09355	COG0028	Belongs to the TPP enzyme family
ARZXY2_RS09370	COG1802	Transcriptional regulator
ARZXY2_RS09385	COG3971	2-oxopent-4-enoate hydratase activity
ARZXY2_RS09420	COG2814	Major facilitator Superfamily
ARZXY2_RS09445	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARZXY2_RS09450	COG0251	oxidation-reduction process
ARZXY2_RS09470	COG0572	uridine kinase
ARZXY2_RS09520	COG2197	response regulator
ARZXY2_RS09525	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ARZXY2_RS09530	COG1846	Transcriptional regulator
ARZXY2_RS09565	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS09590	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_RS09595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ARZXY2_RS09595	COG3608	succinylglutamate desuccinylase aspartoacylase
ARZXY2_RS09605	COG2080	2 iron, 2 sulfur cluster binding
ARZXY2_RS09615	COG2175	clavaminate synthase activity
ARZXY2_RS09620	COG0477	Major facilitator Superfamily
ARZXY2_RS09640	COG3842	ATPase activity
ARZXY2_RS09650	COG1228	amidohydrolase
ARZXY2_RS09655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ARZXY2_RS09660	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ARZXY2_RS09690	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_RS09695	COG1129	ABC transporter
ARZXY2_RS09705	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS09715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ARZXY2_RS09720	COG0129	dihydroxy-acid dehydratase activity
ARZXY2_RS09725	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS09730	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS09735	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_RS09740	COG3962	Belongs to the TPP enzyme family
ARZXY2_RS09760	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARZXY2_RS09765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ARZXY2_RS09795	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ARZXY2_RS09800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ARZXY2_RS09820	COG0857	belongs to the CobB CobQ family
ARZXY2_RS09820	COG0280	phosphate acetyltransferase
ARZXY2_RS09865	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ARZXY2_RS09890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ARZXY2_RS09895	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_RS09900	COG0022	dehydrogenase e1 component
ARZXY2_RS09900	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_RS09905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ARZXY2_RS09935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ARZXY2_RS09955	COG1937	Protein conserved in bacteria
ARZXY2_RS09970	COG0574	Belongs to the PEP-utilizing enzyme family
ARZXY2_RS09970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ARZXY2_RS09990	COG1131	(ABC) transporter
ARZXY2_RS10005	COG0726	polysaccharide deacetylase
ARZXY2_RS10020	COG1131	(ABC) transporter
ARZXY2_RS10060	COG1349	DNA-binding transcription factor activity
ARZXY2_RS10065	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS10075	COG3684	Belongs to the aldolase LacD family
ARZXY2_RS10085	COG1175	transmembrane transport
ARZXY2_RS10090	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS10110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARZXY2_RS10120	COG2132	Multicopper oxidase
ARZXY2_RS10125	COG2217	Heavy metal translocating P-type atpase
ARZXY2_RS10160	COG2801	Transposase and inactivated derivatives
ARZXY2_RS10160	COG3415	Transposase
ARZXY2_RS10190	COG1349	DNA-binding transcription factor activity
ARZXY2_RS10250	COG0070	glutamate synthase
ARZXY2_RS10250	COG0069	glutamate synthase activity
ARZXY2_RS10250	COG0067	glutamate synthase
ARZXY2_RS10255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ARZXY2_RS10260	COG0159	tryptophan synthase activity
ARZXY2_RS10265	COG0133	tryptophan synthase activity
ARZXY2_RS10270	COG0134	indole-3-glycerol-phosphate synthase activity
ARZXY2_RS10290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ARZXY2_RS10300	COG0107	imidazoleglycerol-phosphate synthase activity
ARZXY2_RS10305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ARZXY2_RS10310	COG0140	phosphoribosyl-ATP diphosphatase activity
ARZXY2_RS10315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ARZXY2_RS10320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARZXY2_RS10325	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARZXY2_RS10325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARZXY2_RS10345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ARZXY2_RS10355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ARZXY2_RS10360	COG0242	peptide deformylase activity
ARZXY2_RS10410	COG0531	amino acid
ARZXY2_RS10420	COG3135	benzoate transporter
ARZXY2_RS10440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ARZXY2_RS10455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ARZXY2_RS10480	COG0183	Belongs to the thiolase family
ARZXY2_RS10485	COG1024	Enoyl-CoA hydratase
ARZXY2_RS10485	COG1250	3-hydroxyacyl-CoA dehydrogenase
ARZXY2_RS10490	COG0667	Aldo Keto reductase
ARZXY2_RS10510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ARZXY2_RS10515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ARZXY2_RS10520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ARZXY2_RS10525	COG0531	amino acid
ARZXY2_RS10530	COG0569	domain protein
ARZXY2_RS10555	COG0756	dUTP diphosphatase activity
ARZXY2_RS10575	COG1435	thymidine kinase activity
ARZXY2_RS10590	COG1042	CoA-binding domain protein
ARZXY2_RS10590	COG0045	succinate-CoA ligase (ADP-forming) activity
ARZXY2_RS10590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ARZXY2_RS10595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ARZXY2_RS10615	COG4988	ABC transporter
ARZXY2_RS10620	COG1294	oxidase, subunit
ARZXY2_RS10625	COG1271	oxidase subunit
ARZXY2_RS10650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ARZXY2_RS10670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ARZXY2_RS10675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ARZXY2_RS10680	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_RS10690	COG1764	response to oxidative stress
ARZXY2_RS10695	COG4946	Tricorn protease homolog
ARZXY2_RS10695	COG0793	Belongs to the peptidase S41A family
ARZXY2_RS10700	COG1090	epimerase
ARZXY2_RS10710	COG0321	lipoyl(octanoyl) transferase activity
ARZXY2_RS10715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ARZXY2_RS10745	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ARZXY2_RS10750	COG0174	glutamine synthetase
ARZXY2_RS10755	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ARZXY2_RS10770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ARZXY2_RS10775	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ARZXY2_RS10790	COG0587	DNA-directed DNA polymerase activity
ARZXY2_RS10800	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ARZXY2_RS10815	COG1799	cell septum assembly
ARZXY2_RS10820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ARZXY2_RS10830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ARZXY2_RS10840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ARZXY2_RS10845	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ARZXY2_RS10855	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ARZXY2_RS10860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ARZXY2_RS10870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ARZXY2_RS10875	COG0768	penicillin binding
ARZXY2_RS10885	COG0275	rRNA processing
ARZXY2_RS10890	COG2001	Belongs to the MraZ family
ARZXY2_RS10900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ARZXY2_RS10910	COG0142	geranyltranstransferase activity
ARZXY2_RS10920	COG3942	CHAP domain
ARZXY2_RS10920	COG1388	LysM domain
ARZXY2_RS10925	COG0515	serine threonine protein kinase
ARZXY2_RS10925	COG2815	serine threonine protein kinase
ARZXY2_RS10930	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ARZXY2_RS10955	COG1940	carbohydrate kinase activity
ARZXY2_RS10965	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ARZXY2_RS10990	COG1716	ATPase activity
ARZXY2_RS10995	COG0509	glycine decarboxylation via glycine cleavage system
ARZXY2_RS11000	COG3415	Transposase
ARZXY2_RS11000	COG2801	Transposase and inactivated derivatives
ARZXY2_RS11005	COG2814	Major facilitator Superfamily
ARZXY2_RS11010	COG1846	Transcriptional regulator
ARZXY2_RS11020	COG1160	GTP binding
ARZXY2_RS11030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ARZXY2_RS11045	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ARZXY2_RS11050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ARZXY2_RS11060	COG1301	dicarboxylic acid transport
ARZXY2_RS11065	COG3290	protein histidine kinase activity
ARZXY2_RS11080	COG2079	MmgE PrpD family protein
ARZXY2_RS11085	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ARZXY2_RS11115	COG0504	CTP synthase activity
ARZXY2_RS11120	COG0497	DNA recombination
ARZXY2_RS11125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ARZXY2_RS11140	COG0647	UMP catabolic process
ARZXY2_RS11170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ARZXY2_RS11180	COG2094	Belongs to the DNA glycosylase MPG family
ARZXY2_RS11195	COG0165	Argininosuccinate lyase
ARZXY2_RS11200	COG0137	argininosuccinate synthase activity
ARZXY2_RS11205	COG1438	arginine binding
ARZXY2_RS11210	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ARZXY2_RS11215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ARZXY2_RS11220	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ARZXY2_RS11225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ARZXY2_RS11230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ARZXY2_RS11245	COG0072	phenylalanine-tRNA ligase activity
ARZXY2_RS11245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ARZXY2_RS11250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ARZXY2_RS11265	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ARZXY2_RS11275	COG2816	NAD+ diphosphatase activity
ARZXY2_RS11280	COG2814	Major facilitator Superfamily
ARZXY2_RS11285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ARZXY2_RS11290	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ARZXY2_RS11295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ARZXY2_RS11300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ARZXY2_RS11320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ARZXY2_RS11325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ARZXY2_RS11330	COG0131	Imidazoleglycerol-phosphate dehydratase
ARZXY2_RS11335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ARZXY2_RS11340	COG1388	LysM domain
ARZXY2_RS11345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ARZXY2_RS11355	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ARZXY2_RS11360	COG2813	Specifically methylates the guanine in position
ARZXY2_RS11365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ARZXY2_RS11370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ARZXY2_RS11375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ARZXY2_RS11380	COG2137	regulation of response to DNA damage stimulus
ARZXY2_RS11385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ARZXY2_RS11400	COG1396	sequence-specific DNA binding
ARZXY2_RS11405	COG1546	Belongs to the CinA family
ARZXY2_RS11405	COG1058	Belongs to the CinA family
ARZXY2_RS11415	COG1674	ftsk spoiiie
ARZXY2_RS11420	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ARZXY2_RS11425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARZXY2_RS11445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ARZXY2_RS11455	COG0521	Mo-molybdopterin cofactor biosynthetic process
ARZXY2_RS11475	COG2205	protein histidine kinase activity
ARZXY2_RS11480	COG0745	RESPONSE REGULATOR receiver
ARZXY2_RS11500	COG0612	Peptidase, M16
ARZXY2_RS11505	COG1185	polyribonucleotide nucleotidyltransferase activity
ARZXY2_RS11510	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ARZXY2_RS11530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ARZXY2_RS11540	COG0590	tRNA wobble adenosine to inosine editing
ARZXY2_RS11545	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ARZXY2_RS11550	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ARZXY2_RS11550	COG0481	GTPase activity
ARZXY2_RS11565	COG0779	Required for maturation of 30S ribosomal subunits
ARZXY2_RS11585	COG0442	prolyl-tRNA aminoacylation
ARZXY2_RS11590	COG1131	(ABC) transporter
ARZXY2_RS11610	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ARZXY2_RS11620	COG0750	zinc metalloprotease
ARZXY2_RS11625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ARZXY2_RS11640	COG1653	transport
ARZXY2_RS11645	COG1175	transmembrane transport
ARZXY2_RS11655	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS11695	COG1960	acyl-CoA dehydrogenase activity
ARZXY2_RS11705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ARZXY2_RS11715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ARZXY2_RS11720	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_RS11725	COG0022	dehydrogenase e1 component
ARZXY2_RS11735	COG1522	sequence-specific DNA binding
ARZXY2_RS11745	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ARZXY2_RS11745	COG1796	DNA polymerase
ARZXY2_RS11750	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ARZXY2_RS11760	COG3275	phosphorelay sensor kinase activity
ARZXY2_RS11775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ARZXY2_RS11790	COG0575	Belongs to the CDS family
ARZXY2_RS11795	COG0233	cytoplasmic translational termination
ARZXY2_RS11800	COG0528	UMP kinase activity
ARZXY2_RS11805	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ARZXY2_RS11810	COG0052	Belongs to the universal ribosomal protein uS2 family
ARZXY2_RS11825	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ARZXY2_RS12120	COG0297	glycogen (starch) synthase activity
ARZXY2_RS12150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ARZXY2_RS12155	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ARZXY2_RS12175	COG0358	DNA primase activity
ARZXY2_RS12200	COG0423	glycine-tRNA ligase activity
ARZXY2_RS12240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ARZXY2_RS12245	COG2873	o-acetylhomoserine
ARZXY2_RS12275	COG1940	carbohydrate kinase activity
ARZXY2_RS12280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ARZXY2_RS12285	COG1228	amidohydrolase
ARZXY2_RS12295	COG0156	8-amino-7-oxononanoate synthase activity
ARZXY2_RS12300	COG1063	alcohol dehydrogenase
ARZXY2_RS12310	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS12335	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS12340	COG4209	transmembrane transport
ARZXY2_RS12345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ARZXY2_RS12350	COG0154	amidase activity
ARZXY2_RS12355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ARZXY2_RS12360	COG2851	Citrate transporter
ARZXY2_RS12370	COG4565	transcriptional regulatory protein
ARZXY2_RS12375	COG0251	oxidation-reduction process
ARZXY2_RS12385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARZXY2_RS12390	COG0483	inositol monophosphate 1-phosphatase activity
ARZXY2_RS12395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ARZXY2_RS12405	COG1674	ftsk spoiiie
ARZXY2_RS12445	COG0714	Associated with various cellular activities
ARZXY2_RS12480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ARZXY2_RS12495	COG1823	symporter activity
ARZXY2_RS12510	COG1309	transcriptional regulator
ARZXY2_RS12515	COG2409	Drug exporters of the RND superfamily
ARZXY2_RS12520	COG0424	maF-like protein
ARZXY2_RS12525	COG4770	biotin carboxylase activity
ARZXY2_RS12530	COG0477	Major facilitator Superfamily
ARZXY2_RS12540	COG0243	molybdopterin cofactor binding
ARZXY2_RS12570	COG1621	beta-fructofuranosidase activity
ARZXY2_RS12575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARZXY2_RS12585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ARZXY2_RS12605	COG0659	secondary active sulfate transmembrane transporter activity
ARZXY2_RS12610	COG2824	Alkylphosphonate utilization operon protein PhnA
ARZXY2_RS12615	COG2814	Major facilitator Superfamily
ARZXY2_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS12665	COG0446	pyridine nucleotide-disulphide oxidoreductase
ARZXY2_RS12670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ARZXY2_RS12685	COG0297	glycogen (starch) synthase activity
ARZXY2_RS12705	COG1988	membrane-bound metal-dependent
ARZXY2_RS12715	COG0702	epimerase
ARZXY2_RS12730	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ARZXY2_RS12735	COG0822	iron-sulfur transferase activity
ARZXY2_RS12760	COG0193	aminoacyl-tRNA hydrolase activity
ARZXY2_RS12765	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ARZXY2_RS12770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ARZXY2_RS12775	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ARZXY2_RS12785	COG1309	transcriptional regulator
ARZXY2_RS12795	COG0488	(ABC) transporter
ARZXY2_RS12800	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ARZXY2_RS12805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ARZXY2_RS12810	COG3583	domain protein
ARZXY2_RS12815	COG0084	hydrolase, TatD family'
ARZXY2_RS12820	COG0714	Associated with various cellular activities
ARZXY2_RS12870	COG1376	ErfK ybiS ycfS ynhG family protein
ARZXY2_RS12875	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ARZXY2_RS12925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ARZXY2_RS12935	COG1482	cell wall glycoprotein biosynthetic process
ARZXY2_RS12945	COG1494	fructose-1,6-bisphosphatase
ARZXY2_RS12955	COG0288	reversible hydration of carbon dioxide
ARZXY2_RS12960	COG0114	fumarate hydratase activity
ARZXY2_RS12980	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ARZXY2_RS12985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ARZXY2_RS12995	COG1331	Highly conserved protein containing a thioredoxin domain
ARZXY2_RS13005	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ARZXY2_RS13015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ARZXY2_RS13025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ARZXY2_RS13035	COG2017	converts alpha-aldose to the beta-anomer
ARZXY2_RS13045	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ARZXY2_RS13050	COG0183	Belongs to the thiolase family
ARZXY2_RS13060	COG0559	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_RS13100	COG1252	NADH dehydrogenase
ARZXY2_RS13125	COG0148	phosphopyruvate hydratase activity
ARZXY2_RS13135	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ARZXY2_RS13140	COG0586	Pfam SNARE associated Golgi protein
ARZXY2_RS13160	COG1079	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_RS13165	COG4603	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_RS13170	COG3845	ABC transporter
ARZXY2_RS13175	COG1744	ABC transporter substrate-binding protein PnrA-like
ARZXY2_RS13180	COG2130	NADP-dependent
ARZXY2_RS13185	COG1764	response to oxidative stress
ARZXY2_RS13190	COG1846	Transcriptional regulator
ARZXY2_RS13195	COG1473	amidohydrolase
ARZXY2_RS13195	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARZXY2_RS13205	COG2009	succinate dehydrogenase
ARZXY2_RS13220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ARZXY2_RS13250	COG0180	Tryptophanyl-tRNA synthetase
ARZXY2_RS13275	COG1131	(ABC) transporter
ARZXY2_RS13280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ARZXY2_RS13285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARZXY2_RS13310	COG0531	amino acid
ARZXY2_RS13315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ARZXY2_RS13330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ARZXY2_RS13340	COG1129	ABC transporter
ARZXY2_RS13345	COG4214	carbohydrate transport
ARZXY2_RS13350	COG4213	ABC transporter substrate-binding protein
ARZXY2_RS13355	COG1136	(ABC) transporter
ARZXY2_RS13355	COG0577	efflux transmembrane transporter activity
ARZXY2_RS13360	COG1136	(ABC) transporter
ARZXY2_RS13360	COG0577	efflux transmembrane transporter activity
ARZXY2_RS13370	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS13385	COG2838	Isocitrate dehydrogenase
ARZXY2_RS13395	COG0138	bifunctional purine biosynthesis protein purh
ARZXY2_RS13405	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ARZXY2_RS13410	COG2271	Major facilitator Superfamily
ARZXY2_RS13440	COG0484	heat shock protein binding
ARZXY2_RS13445	COG0071	Belongs to the small heat shock protein (HSP20) family
ARZXY2_RS13470	COG2801	Transposase and inactivated derivatives
ARZXY2_RS13470	COG3415	Transposase
ARZXY2_RS13485	COG1278	Cold shock
ARZXY2_RS13490	COG4942	peptidase
ARZXY2_RS13520	COG0577	efflux transmembrane transporter activity
ARZXY2_RS13520	COG1136	(ABC) transporter
ARZXY2_RS13530	COG2072	flavoprotein involved in K transport
ARZXY2_RS13600	COG3973	AAA domain
ARZXY2_RS13615	COG0477	Major facilitator Superfamily
ARZXY2_RS13630	COG1609	Transcriptional regulator
ARZXY2_RS13650	COG1472	Belongs to the glycosyl hydrolase 3 family
ARZXY2_RS13670	COG0402	S-adenosylhomocysteine deaminase activity
ARZXY2_RS13680	COG1653	transport
ARZXY2_RS13690	COG4209	transmembrane transport
ARZXY2_RS13700	COG0640	Transcriptional regulator
ARZXY2_RS13705	COG1254	Belongs to the acylphosphatase family
ARZXY2_RS13715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ARZXY2_RS13730	COG3835	regulator
ARZXY2_RS13740	COG0511	ligase activity, forming carbon-carbon bonds
ARZXY2_RS13745	COG0439	Biotin carboxylase
ARZXY2_RS13750	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ARZXY2_RS13755	COG1984	allophanate hydrolase subunit 2
ARZXY2_RS13790	COG0149	triose-phosphate isomerase activity
ARZXY2_RS13795	COG2271	Major facilitator Superfamily
ARZXY2_RS13800	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS13805	COG1250	3-hydroxyacyl-CoA dehydrogenase
ARZXY2_RS13810	COG0698	ribose 5-phosphate isomerase
ARZXY2_RS13815	COG2376	Dihydroxyacetone kinase
ARZXY2_RS13830	COG1902	pentaerythritol trinitrate reductase activity
ARZXY2_RS13835	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ARZXY2_RS13855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ARZXY2_RS13875	COG1396	sequence-specific DNA binding
ARZXY2_RS13890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ARZXY2_RS13895	COG1024	Enoyl-CoA hydratase
ARZXY2_RS13905	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS13910	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_RS13925	COG2205	protein histidine kinase activity
ARZXY2_RS13940	COG1401	restriction endodeoxyribonuclease activity
ARZXY2_RS13950	COG3142	Participates in the control of copper homeostasis
ARZXY2_RS13980	COG0028	Belongs to the TPP enzyme family
ARZXY2_RS13990	COG1396	sequence-specific DNA binding
ARZXY2_RS14030	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS14040	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_RS14050	COG2188	Transcriptional regulator
ARZXY2_RS14055	COG3718	enzyme involved in inositol metabolism
ARZXY2_RS14060	COG1082	Xylose isomerase domain protein TIM barrel
ARZXY2_RS14065	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS14080	COG3962	Belongs to the TPP enzyme family
ARZXY2_RS14090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARZXY2_RS14095	COG1942	4-Oxalocrotonate Tautomerase
ARZXY2_RS14105	COG0045	succinate-CoA ligase (ADP-forming) activity
ARZXY2_RS14120	COG0483	inositol monophosphate 1-phosphatase activity
ARZXY2_RS14155	COG1132	(ABC) transporter
ARZXY2_RS14160	COG0488	(ABC) transporter
ARZXY2_RS14175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARZXY2_RS14180	COG0765	amino acid transport
ARZXY2_RS14185	COG1126	abc transporter atp-binding protein
ARZXY2_RS14205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ARZXY2_RS14215	COG0746	molybdenum cofactor guanylyltransferase activity
ARZXY2_RS14230	COG0791	NLP P60 protein
ARZXY2_RS14230	COG1388	LysM domain
ARZXY2_RS14230	COG3103	Sh3 type 3 domain protein
ARZXY2_RS14235	COG0739	heme binding
ARZXY2_RS14245	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ARZXY2_RS14255	COG1278	Cold shock
ARZXY2_RS14280	COG2132	Multicopper oxidase
ARZXY2_RS14300	COG0745	RESPONSE REGULATOR receiver
ARZXY2_RS14305	COG2205	protein histidine kinase activity
ARZXY2_RS14315	COG0328	RNA-DNA hybrid ribonuclease activity
ARZXY2_RS14320	COG0459	protein refolding
ARZXY2_RS14340	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ARZXY2_RS14365	COG1136	(ABC) transporter
ARZXY2_RS14365	COG0577	efflux transmembrane transporter activity
ARZXY2_RS14380	COG1864	DNA RNA non-specific endonuclease
ARZXY2_RS14380	COG3591	Belongs to the peptidase S1B family
ARZXY2_RS14385	COG1760	l-serine dehydratase
ARZXY2_RS14390	COG0509	glycine decarboxylation via glycine cleavage system
ARZXY2_RS14395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ARZXY2_RS14400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ARZXY2_RS14400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ARZXY2_RS14410	COG0477	Major facilitator Superfamily
ARZXY2_RS14425	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ARZXY2_RS14435	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ARZXY2_RS14440	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ARZXY2_RS14455	COG1338	Plays a role in the flagellum-specific transport system
ARZXY2_RS14475	COG1360	Flagellar Motor Protein
ARZXY2_RS14480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ARZXY2_RS14495	COG3550	peptidyl-serine autophosphorylation
ARZXY2_RS14515	COG0791	NLP P60 protein
ARZXY2_RS14525	COG1157	protein secretion by the type III secretion system
ARZXY2_RS14535	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ARZXY2_RS14540	COG1766	The M ring may be actively involved in energy transduction
ARZXY2_RS14545	COG1677	Flagellar hook-basal body complex protein FliE
ARZXY2_RS14555	COG1815	bacterial-type flagellum-dependent cell motility
ARZXY2_RS14585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ARZXY2_RS14595	COG4786	Flagellar basal body rod
ARZXY2_RS14595	COG1256	bacterial-type flagellum assembly
ARZXY2_RS14605	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ARZXY2_RS14620	COG1609	Transcriptional regulator
ARZXY2_RS14630	COG0492	ferredoxin-NADP+ reductase activity
ARZXY2_RS14645	COG2957	Belongs to the agmatine deiminase family
ARZXY2_RS14670	COG0579	oxidoreductase
ARZXY2_RS14710	COG1252	NADH dehydrogenase
ARZXY2_RS14720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ARZXY2_RS14735	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS14740	COG0475	glutathione-regulated potassium exporter activity
ARZXY2_RS14770	COG3842	ATPase activity
ARZXY2_RS14800	COG0277	FAD linked oxidase domain protein
ARZXY2_RS14830	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ARZXY2_RS14840	COG0366	Alpha amylase catalytic
ARZXY2_RS14880	COG0215	cysteine-tRNA ligase activity
ARZXY2_RS14890	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ARZXY2_RS14895	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ARZXY2_RS14915	COG5002	protein histidine kinase activity
ARZXY2_RS14925	COG0588	phosphoglycerate mutase activity
ARZXY2_RS14945	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ARZXY2_RS14950	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ARZXY2_RS14995	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_RS15010	COG0656	L-ascorbic acid biosynthetic process
ARZXY2_RS15030	COG1966	Carbon starvation protein
ARZXY2_RS15040	COG0604	alcohol dehydrogenase
ARZXY2_RS15040	COG3321	synthase
ARZXY2_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS15055	COG1113	amino acid transport
ARZXY2_RS15065	COG1505	serine-type exopeptidase activity
ARZXY2_RS15080	COG0514	ATP-dependent DNA helicase (RecQ)
ARZXY2_RS15085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARZXY2_RS15100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ARZXY2_RS15100	COG1017	nitric oxide dioxygenase activity
ARZXY2_RS15105	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ARZXY2_RS15135	COG0747	negative chemotaxis
ARZXY2_RS15140	COG0601	transmembrane transport
ARZXY2_RS15145	COG0444	Belongs to the ABC transporter superfamily
ARZXY2_RS15150	COG4608	Belongs to the ABC transporter superfamily
ARZXY2_RS15155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARZXY2_RS15160	COG1940	carbohydrate kinase activity
ARZXY2_RS15165	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ARZXY2_RS15175	COG1129	ABC transporter
ARZXY2_RS15180	COG1511	domain protein
ARZXY2_RS15185	COG1309	transcriptional regulator
ARZXY2_RS15195	COG0697	spore germination
ARZXY2_RS15200	COG0583	DNA-binding transcription factor activity
ARZXY2_RS15205	COG2062	phosphohistidine phosphatase, SixA
ARZXY2_RS15235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ARZXY2_RS15245	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_RS15320	COG1201	RNA secondary structure unwinding
ARZXY2_RS15325	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ARZXY2_RS15330	COG2364	Membrane
ARZXY2_RS15335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ARZXY2_RS15350	COG0564	pseudouridine synthase activity
ARZXY2_RS15360	COG0586	Pfam SNARE associated Golgi protein
ARZXY2_RS15370	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ARZXY2_RS15395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ARZXY2_RS15420	COG1960	acyl-CoA dehydrogenase activity
ARZXY2_RS15445	COG3842	ATPase activity
ARZXY2_RS15460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARZXY2_RS15465	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ARZXY2_RS15470	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_RS15475	COG0028	Belongs to the TPP enzyme family
ARZXY2_RS15480	COG0477	Major facilitator Superfamily
ARZXY2_RS15485	COG2508	Transcriptional regulator
ARZXY2_RS15490	COG0477	Major facilitator Superfamily
ARZXY2_RS15500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ARZXY2_RS15520	COG0343	queuine tRNA-ribosyltransferase activity
ARZXY2_RS15530	COG1309	transcriptional regulator
ARZXY2_RS15535	COG1090	epimerase
ARZXY2_RS15550	COG0477	Major facilitator Superfamily
ARZXY2_RS15555	COG0745	RESPONSE REGULATOR receiver
ARZXY2_RS15560	COG0642	Histidine kinase
ARZXY2_RS15570	COG0351	phosphomethylpyrimidine kinase
ARZXY2_RS15580	COG1309	transcriptional regulator
ARZXY2_RS15585	COG1476	TRANSCRIPTIONal
ARZXY2_RS15595	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ARZXY2_RS15615	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS15620	COG2182	Extracellular solute-binding protein
ARZXY2_RS15630	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS15650	COG2855	membrane
ARZXY2_RS15660	COG4565	transcriptional regulatory protein
ARZXY2_RS15665	COG3290	protein histidine kinase activity
ARZXY2_RS15685	COG0589	response to stress
ARZXY2_RS15700	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_RS15715	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS15720	COG1175	transmembrane transport
ARZXY2_RS15730	COG1609	Transcriptional regulator
ARZXY2_RS15735	COG1309	transcriptional regulator
ARZXY2_RS15765	COG0741	lytic transglycosylase activity
ARZXY2_RS15765	COG0739	heme binding
ARZXY2_RS15765	COG1196	nuclear chromosome segregation
ARZXY2_RS15775	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_RS15790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ARZXY2_RS15805	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ARZXY2_RS15835	COG5416	Lipopolysaccharide assembly protein A domain
ARZXY2_RS15850	COG1846	Transcriptional regulator
ARZXY2_RS15880	COG1404	Belongs to the peptidase S8 family
ARZXY2_RS15890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARZXY2_RS15910	COG0047	phosphoribosylformylglycinamidine synthase activity
ARZXY2_RS15915	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ARZXY2_RS15930	COG3706	GGDEF domain
ARZXY2_RS15945	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS15950	COG1175	transmembrane transport
ARZXY2_RS15955	COG1653	transport
ARZXY2_RS15960	COG2315	Protein conserved in bacteria
ARZXY2_RS15970	COG1832	CoA-binding protein
ARZXY2_RS15990	COG1609	Transcriptional regulator
ARZXY2_RS15995	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS16000	COG1175	transmembrane transport
ARZXY2_RS16015	COG1621	beta-fructofuranosidase activity
ARZXY2_RS16025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ARZXY2_RS16025	COG3321	synthase
ARZXY2_RS16025	COG0604	alcohol dehydrogenase
ARZXY2_RS16025	COG4221	oxidoreductase activity
ARZXY2_RS16030	COG0129	dihydroxy-acid dehydratase activity
ARZXY2_RS16040	COG2271	Major facilitator Superfamily
ARZXY2_RS16065	COG0477	Major facilitator Superfamily
ARZXY2_RS16070	COG1609	Transcriptional regulator
ARZXY2_RS16080	COG0765	amino acid transport
ARZXY2_RS16085	COG1126	abc transporter atp-binding protein
ARZXY2_RS16090	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS16095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ARZXY2_RS16125	COG2814	Major facilitator Superfamily
ARZXY2_RS16135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ARZXY2_RS16160	COG0357	Ribosomal RNA small subunit methyltransferase G
ARZXY2_RS16160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ARZXY2_RS16195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ARZXY2_RS16205	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_RS16215	COG0246	Mannitol dehydrogenase
ARZXY2_RS16220	COG1904	glucuronate isomerase
ARZXY2_RS16225	COG1609	Transcriptional regulator
ARZXY2_RS16230	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS16245	COG0444	Belongs to the ABC transporter superfamily
ARZXY2_RS16255	COG0747	negative chemotaxis
ARZXY2_RS16270	COG1609	Transcriptional regulator
ARZXY2_RS16285	COG0789	Transcriptional regulator
ARZXY2_RS16300	COG3328	transposase activity
ARZXY2_RS16310	COG1960	acyl-CoA dehydrogenase activity
ARZXY2_RS16315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARZXY2_RS16350	COG1024	Enoyl-CoA hydratase
ARZXY2_RS16360	COG0415	Belongs to the DNA photolyase family
ARZXY2_RS16385	COG0583	DNA-binding transcription factor activity
ARZXY2_RS16395	COG1473	amidohydrolase
ARZXY2_RS16405	COG0174	glutamine synthetase
ARZXY2_RS16410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARZXY2_RS16445	COG1802	Transcriptional regulator
ARZXY2_RS16460	COG3404	Formiminotransferase-cyclodeaminase
ARZXY2_RS16465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ARZXY2_RS16475	COG1063	alcohol dehydrogenase
ARZXY2_RS16480	COG0303	'Molybdopterin
ARZXY2_RS16485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ARZXY2_RS16495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ARZXY2_RS16520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ARZXY2_RS16535	COG0666	response to abiotic stimulus
ARZXY2_RS16545	COG4585	Histidine kinase
ARZXY2_RS16550	COG2197	response regulator
ARZXY2_RS16570	COG1609	Transcriptional regulator
ARZXY2_RS16590	COG2182	Extracellular solute-binding protein
ARZXY2_RS16655	COG1285	pathogenesis
ARZXY2_RS16660	COG1175	transmembrane transport
ARZXY2_RS16665	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS16675	COG1802	Transcriptional regulator
ARZXY2_RS16715	COG1609	Transcriptional regulator
ARZXY2_RS16730	COG3848	Pyruvate phosphate dikinase
ARZXY2_RS16730	COG0574	Belongs to the PEP-utilizing enzyme family
ARZXY2_RS16755	COG2252	PERMEase
ARZXY2_RS16760	COG0010	Belongs to the arginase family
ARZXY2_RS16770	COG2902	Dehydrogenase
ARZXY2_RS16790	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ARZXY2_RS16810	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS16830	COG4122	O-methyltransferase activity
ARZXY2_RS16865	COG2733	membrane
ARZXY2_RS16870	COG1984	allophanate hydrolase subunit 2
ARZXY2_RS16875	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ARZXY2_RS16895	COG2828	Protein conserved in bacteria
ARZXY2_RS16905	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS16915	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS16920	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS16930	COG0028	Belongs to the TPP enzyme family
ARZXY2_RS16935	COG0477	Major facilitator Superfamily
ARZXY2_RS16960	COG2301	Belongs to the HpcH HpaI aldolase family
ARZXY2_RS16965	COG4770	biotin carboxylase activity
ARZXY2_RS16975	COG0318	PFAM AMP-dependent synthetase and ligase
ARZXY2_RS16985	COG1902	pentaerythritol trinitrate reductase activity
ARZXY2_RS16990	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS16995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_RS17005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ARZXY2_RS17025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARZXY2_RS17040	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARZXY2_RS17070	COG3971	2-oxopent-4-enoate hydratase activity
ARZXY2_RS17075	COG1414	Transcriptional regulator
ARZXY2_RS17085	COG3384	dioxygenase
ARZXY2_RS17090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARZXY2_RS17100	COG3842	ATPase activity
ARZXY2_RS17115	COG1846	Transcriptional regulator
ARZXY2_RS17120	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ARZXY2_RS17125	COG0142	geranyltranstransferase activity
ARZXY2_RS17150	COG1846	Transcriptional regulator
ARZXY2_RS17175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARZXY2_RS17180	COG1609	Transcriptional regulator
ARZXY2_RS17200	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARZXY2_RS17225	COG1349	DNA-binding transcription factor activity
ARZXY2_RS17235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ARZXY2_RS17235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ARZXY2_RS17235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ARZXY2_RS17280	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ARZXY2_RS17300	COG2890	protein-(glutamine-N5) methyltransferase activity
ARZXY2_RS17305	COG0477	Major facilitator Superfamily
ARZXY2_RS17320	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_RS17330	COG1175	transmembrane transport
ARZXY2_RS17340	COG2186	Transcriptional regulator
ARZXY2_RS17345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ARZXY2_RS17350	COG0697	spore germination
ARZXY2_RS17385	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ARZXY2_RS17440	COG2610	gluconate transmembrane transporter activity
ARZXY2_RS17445	COG2084	Dehydrogenase
ARZXY2_RS17460	COG2186	Transcriptional regulator
ARZXY2_RS17480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ARZXY2_RS17490	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ARZXY2_RS17500	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS17505	COG3360	Dodecin
ARZXY2_RS17520	COG0667	Aldo Keto reductase
ARZXY2_RS17530	COG0656	L-ascorbic acid biosynthetic process
ARZXY2_RS17535	COG2706	6-phosphogluconolactonase activity
ARZXY2_RS17550	COG1595	DNA-templated transcription, initiation
ARZXY2_RS17555	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ARZXY2_RS17560	COG0829	nickel cation binding
ARZXY2_RS17565	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ARZXY2_RS17570	COG0830	nickel cation binding
ARZXY2_RS17575	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ARZXY2_RS17580	COG0804	urea catabolic process
ARZXY2_RS17585	COG0832	Belongs to the urease beta subunit family
ARZXY2_RS17590	COG0831	urea catabolic process
ARZXY2_RS17645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ARZXY2_RS17670	COG0671	phosphoesterase, PA-phosphatase related
ARZXY2_RS17680	COG0492	ferredoxin-NADP+ reductase activity
ARZXY2_RS17685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARZXY2_RS17705	COG1247	-acetyltransferase
ARZXY2_RS17730	COG3559	Exporter of polyketide antibiotics
ARZXY2_RS17735	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ARZXY2_RS17745	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ARZXY2_RS17785	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS17800	COG3237	CsbD-like
ARZXY2_RS17805	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ARZXY2_RS17810	COG1461	Dihydroxyacetone kinase
ARZXY2_RS17815	COG2376	Dihydroxyacetone kinase
ARZXY2_RS17835	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ARZXY2_RS17840	COG1506	peptidase
ARZXY2_RS17840	COG0823	Involved in the tonB-independent uptake of proteins
ARZXY2_RS17860	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ARZXY2_RS17900	COG0477	Major facilitator Superfamily
ARZXY2_RS17925	COG3328	transposase activity
ARZXY2_RS17945	COG2814	Major facilitator Superfamily
ARZXY2_RS17950	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ARZXY2_RS17980	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ARZXY2_RS17990	COG0302	gtp cyclohydrolase
ARZXY2_RS17995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARZXY2_RS18010	COG0037	tRNA processing
ARZXY2_RS18020	COG2027	D-alanyl-D-alanine carboxypeptidase
ARZXY2_RS18075	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ARZXY2_RS18075	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ARZXY2_RS18090	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ARZXY2_RS18090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ARZXY2_RS18095	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ARZXY2_RS18100	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_RS18110	COG0859	PFAM glycosyl transferase family 9
ARZXY2_RS18115	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ARZXY2_RS18120	COG0859	PFAM glycosyl transferase family 9
ARZXY2_RS18125	COG1191	sigma factor activity
ARZXY2_RS18145	COG0561	phosphatase activity
ARZXY2_RS18150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ARZXY2_RS18155	COG1597	lipid kinase activity
ARZXY2_RS18165	COG0077	Prephenate dehydratase
ARZXY2_RS18170	COG0425	Belongs to the sulfur carrier protein TusA family
ARZXY2_RS18170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARZXY2_RS18175	COG3340	Belongs to the peptidase S51 family
ARZXY2_RS18185	COG3104	oligopeptide transport
ARZXY2_RS18200	COG0778	Nitroreductase
ARZXY2_RS18205	COG2801	Transposase and inactivated derivatives
ARZXY2_RS18205	COG3415	Transposase
ARZXY2_RS18210	COG2233	PERMEase
ARZXY2_RS18220	COG3655	Transcriptional regulator
ARZXY2_RS18230	COG0693	protein deglycase activity
ARZXY2_RS18240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ARZXY2_RS18250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_RS18260	COG1929	Belongs to the glycerate kinase type-1 family
ARZXY2_RS18265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARZXY2_RS18270	COG3250	beta-galactosidase activity
ARZXY2_RS18275	COG0584	glycerophosphoryl diester phosphodiesterase
ARZXY2_RS18285	COG0561	phosphatase activity
ARZXY2_RS18290	COG0435	Glutathione S-transferase
ARZXY2_RS18310	COG0659	secondary active sulfate transmembrane transporter activity
ARZXY2_RS18315	COG0277	FAD linked oxidase domain protein
ARZXY2_RS18320	COG4770	biotin carboxylase activity
ARZXY2_RS18325	COG1984	allophanate hydrolase subunit 2
ARZXY2_RS18330	COG0477	Major facilitator Superfamily
ARZXY2_RS18335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ARZXY2_RS18340	COG2186	Transcriptional regulator
ARZXY2_RS18355	COG0346	lactoylglutathione lyase activity
ARZXY2_RS18415	COG1716	ATPase activity
ARZXY2_RS18420	COG1716	ATPase activity
ARZXY2_RS18435	COG0768	penicillin binding
ARZXY2_RS18440	COG0515	serine threonine protein kinase
ARZXY2_RS18445	COG0515	serine threonine protein kinase
ARZXY2_RS18455	COG3764	Sortase (surface protein transpeptidase)
ARZXY2_RS18470	COG1595	DNA-templated transcription, initiation
ARZXY2_RS18475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ARZXY2_RS18475	COG2169	Transcriptional regulator
ARZXY2_RS18485	COG2818	Glycosylase
ARZXY2_RS18495	COG0457	Tetratricopeptide repeat
ARZXY2_RS18495	COG0705	Rhomboid family
ARZXY2_RS18510	COG1215	transferase activity, transferring glycosyl groups
ARZXY2_RS18520	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ARZXY2_RS18520	COG3291	Pkd domain containing protein
ARZXY2_RS18535	COG3266	domain, Protein
ARZXY2_RS18545	COG0187	DNA topoisomerase II activity
ARZXY2_RS18550	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ARZXY2_RS18555	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ARZXY2_RS18560	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ARZXY2_RS18565	COG0592	DNA-directed DNA polymerase activity
ARZXY2_RS18570	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ARZXY2_RS18575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ARZXY2_RS18580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ARZXY2_RS18585	COG0706	membrane insertase activity
ARZXY2_RS18595	COG0357	Ribosomal RNA small subunit methyltransferase G
ARZXY2_RS18600	COG1192	Involved in chromosome partitioning
ARZXY2_RS18610	COG3118	belongs to the thioredoxin family
ARZXY2_RS18615	COG0492	ferredoxin-NADP+ reductase activity
ARZXY2_RS18635	COG0617	tRNA 3'-terminal CCA addition
ARZXY2_RS18640	COG0406	alpha-ribazole phosphatase activity
ARZXY2_RS18655	COG2910	NAD(P)H-binding
ARZXY2_RS18660	COG1733	regulation of RNA biosynthetic process
ARZXY2_RS18665	COG1136	(ABC) transporter
ARZXY2_RS18675	COG4585	Histidine kinase
ARZXY2_RS18680	COG2197	response regulator
ARZXY2_RS18685	COG0768	penicillin binding
ARZXY2_RS18695	COG0488	(ABC) transporter
ARZXY2_RS18700	COG3415	Transposase
ARZXY2_RS18700	COG2801	Transposase and inactivated derivatives
ARZXY2_RS18710	COG0738	Major facilitator superfamily
ARZXY2_RS18720	COG1597	lipid kinase activity
ARZXY2_RS18725	COG1131	(ABC) transporter
ARZXY2_RS18735	COG4585	Histidine kinase
ARZXY2_RS18740	COG2197	response regulator
ARZXY2_RS18745	COG1362	aminopeptidase activity
ARZXY2_RS18750	COG1113	amino acid transport
ARZXY2_RS18775	COG1742	UPF0060 membrane protein
ARZXY2_RS18780	COG0360	Binds together with S18 to 16S ribosomal RNA
ARZXY2_RS18790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ARZXY2_RS18795	COG0359	binds to the 23S rRNA
ARZXY2_RS18850	COG0305	Participates in initiation and elongation during chromosome replication
ARZXY2_RS18865	COG0698	ribose 5-phosphate isomerase
ARZXY2_RS18870	COG2376	Dihydroxyacetone kinase
ARZXY2_RS18875	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS18880	COG1082	Xylose isomerase domain protein TIM barrel
ARZXY2_RS18890	COG3959	Transketolase, thiamine diphosphate binding domain
ARZXY2_RS18895	COG3958	Transketolase
ARZXY2_RS18910	COG1607	acyl-coa hydrolase
ARZXY2_RS18965	COG1937	Protein conserved in bacteria
ARZXY2_RS19025	COG2610	gluconate transmembrane transporter activity
ARZXY2_RS19065	COG0583	DNA-binding transcription factor activity
ARZXY2_RS19075	COG3384	dioxygenase
ARZXY2_RS19085	COG3971	2-oxopent-4-enoate hydratase activity
ARZXY2_RS19100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARZXY2_RS19105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ARZXY2_RS19105	COG1116	anion transmembrane transporter activity
ARZXY2_RS19110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARZXY2_RS19115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARZXY2_RS19120	COG1116	anion transmembrane transporter activity
ARZXY2_RS19125	COG1309	transcriptional regulator
ARZXY2_RS19150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARZXY2_RS19190	COG0800	Aldolase
ARZXY2_RS19195	COG2186	Transcriptional regulator
ARZXY2_RS19205	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_RS19210	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_RS19225	COG2376	Dihydroxyacetone kinase
ARZXY2_RS19230	COG1461	Dihydroxyacetone kinase
ARZXY2_RS19235	COG0693	protein deglycase activity
ARZXY2_RS19250	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_RS19255	COG3386	PFAM SMP-30 Gluconolaconase
ARZXY2_RS19260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ARZXY2_RS19265	COG0693	protein deglycase activity
ARZXY2_RS19280	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ARZXY2_RS19305	COG4974	Belongs to the 'phage' integrase family
ARZXY2_RS19315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ARZXY2_RS19325	COG2252	PERMEase
ARZXY2_RS19345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ARZXY2_RS19495	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ARZXY2_RS19500	COG0686	Belongs to the AlaDH PNT family
ARZXY2_RS19565	COG1802	Transcriptional regulator
ARZXY2_RS19570	COG2271	Major facilitator Superfamily
ARZXY2_RS19575	COG1970	mechanosensitive ion channel activity
ARZXY2_RS19580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ARZXY2_RS19585	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ARZXY2_RS19585	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ARZXY2_RS19590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ARZXY2_RS19595	COG0509	glycine decarboxylation via glycine cleavage system
ARZXY2_RS19600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARZXY2_RS19610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ARZXY2_RS19720	COG1846	Transcriptional regulator
ARZXY2_RS19725	COG0515	serine threonine protein kinase
ARZXY2_RS19730	COG2261	transglycosylase associated protein
ARZXY2_RS19745	COG0243	molybdopterin cofactor binding
ARZXY2_RS19755	COG2814	Major facilitator Superfamily
ARZXY2_RS19770	COG3387	PFAM Glycoside hydrolase 15-related
ARZXY2_RS19800	COG0515	serine threonine protein kinase
ARZXY2_RS19800	COG2815	serine threonine protein kinase
ARZXY2_RS19815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARZXY2_RS19820	COG1621	beta-fructofuranosidase activity
ARZXY2_RS19825	COG1609	Transcriptional regulator
ARZXY2_RS19830	COG0395	ABC-type sugar transport system, permease component
ARZXY2_RS19840	COG1653	transport
ARZXY2_RS19855	COG1621	beta-fructofuranosidase activity
ARZXY2_RS19870	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_RS19880	COG2207	Transcriptional regulator
ARZXY2_RS19880	COG3708	Transcriptional regulator
ARZXY2_RS19890	COG2261	transglycosylase associated protein
ARZXY2_RS19920	COG0436	Aminotransferase
ARZXY2_RS19925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ARZXY2_RS19940	COG0583	DNA-binding transcription factor activity
ARZXY2_RS19945	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ARZXY2_RS19950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ARZXY2_RS19955	COG1984	allophanate hydrolase subunit 2
ARZXY2_RS19960	COG0477	Major facilitator Superfamily
ARZXY2_RS19965	COG4221	oxidoreductase activity
ARZXY2_RS19970	COG1607	acyl-coa hydrolase
ARZXY2_RS19985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ARZXY2_RS20000	COG1950	PFAM Membrane protein of
ARZXY2_RS20005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ARZXY2_RS20015	COG0022	dehydrogenase e1 component
ARZXY2_RS20020	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_RS20060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ARZXY2_RS20090	COG1309	transcriptional regulator
ARZXY2_RS20120	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS20150	COG0686	Belongs to the AlaDH PNT family
ARZXY2_RS20170	COG1793	dna ligase
ARZXY2_RS20180	COG2267	carboxylic ester hydrolase activity
ARZXY2_RS20200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ARZXY2_RS20210	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ARZXY2_RS20210	COG2213	PTS system mannitol-specific
ARZXY2_RS20215	COG0246	Mannitol dehydrogenase
ARZXY2_RS20225	COG1113	amino acid transport
ARZXY2_RS20250	COG1846	Transcriptional regulator
ARZXY2_RS20255	COG2814	Major facilitator Superfamily
ARZXY2_RS20260	COG0477	Major facilitator Superfamily
ARZXY2_RS20265	COG0477	Major facilitator Superfamily
ARZXY2_RS20270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ARZXY2_RS20305	COG1309	transcriptional regulator
ARZXY2_RS20310	COG0281	malic enzyme
ARZXY2_RS20340	COG1760	l-serine dehydratase
ARZXY2_RS20365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARZXY2_RS20375	COG0477	Major facilitator Superfamily
ARZXY2_RS20385	COG1414	Transcriptional regulator
ARZXY2_RS20405	COG1280	lysine exporter protein (LysE YggA)
ARZXY2_RS20410	COG1522	sequence-specific DNA binding
ARZXY2_RS20420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ARZXY2_RS20425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ARZXY2_RS20430	COG4221	oxidoreductase activity
ARZXY2_RS20435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARZXY2_RS20445	COG2186	Transcriptional regulator
ARZXY2_RS20455	COG1027	Aspartate ammonia-lyase
ARZXY2_RS20465	COG2186	Transcriptional regulator
ARZXY2_RS20520	COG0667	Aldo Keto reductase
ARZXY2_RS20535	COG3012	SEC-C Motif Domain Protein
ARZXY2_RS20575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ARZXY2_RS20580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ARZXY2_RS20585	COG1120	ATPase activity
ARZXY2_RS20610	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ARZXY2_RS20615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ARZXY2_RS20620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ARZXY2_RS21040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ARZXY2_RS21040	COG2111	Na H antiporter
ARZXY2_RS21595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ARZXY2_RS21720	COG0542	response to heat
ARZXY2_RS22330	COG0673	inositol 2-dehydrogenase activity
ARZXY2_RS22790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARZXY2_RS22800	COG3387	PFAM Glycoside hydrolase 15-related
ARZXY2_RS22820	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity